KRAB-A domain-containing protein

Overview


Name	KRAB-A domain-containing protein
Smed ID	SMED30025997
Length (bp)	1255

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of KRAB-A domain-containing protein (SMED30025997) t-SNE clustered cells

Violin plots show distribution of expression levels for KRAB-A domain-containing protein (SMED30025997) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025997

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Published Transcript	Transcriptome	Publication
epidermis	SMED30025997	dd_Smed_v4_18600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30025997	dd_Smed_v4_18600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30025997	dd_Smed_v4_18600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30025997	dd_Smed_v4_18600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30025997	dd_Smed_v4_18600_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Xenopus
Match: anxa6 (annexin A6 [Source:Xenbase;Acc:XB-GENE-989741])

HSP 1 Score: 58.9214 bits (141), Expect = 1.043e-8
Identity = 35/119 (29.41%), Postives = 66/119 (55.46%), Query Frame = 1

Query:  904 IKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGEL-INITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            + +  +L++I+ +   +F A+    GRTH  +HK+ T  +L I    YR    +  +++  I  +   G I   +SP+ +P++ V +K+    R C+D+R+LN V  + A+ MP +DE+
Sbjct:  299 LSQQDQLRKILRSYSPMFSANP---GRTHWAEHKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGS-TRFCVDYRRLNDVTTTDAYPMPRVDEL 413

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000023941.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV463742.1:21:4282:-1 gene:ENSXETG00000015734.1 transcript:ENSXETT00000023941.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 1.370e-7
Identity = 35/114 (30.70%), Postives = 64/114 (56.14%), Query Frame = 1

Query:  919 KLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGEL-INITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            +L++I+ +   +F A+    GRTH  +HK+ T  +L I    YR    +  +++  I  +   G I   +SP+ +P++ V +K+    R C+D+R+LN V  + A+ MP +DE+
Sbjct: 1037 QLRKILRSYSPMFSANP---GRTHWAEHKVDTGTQLPIRSPAYRVAEAVRPEMKSQIDEMLAFGVITPSHSPWASPVVLVPKKDGS-TRFCVDYRRLNDVTTTDAYPMPRVDEL 1146

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Xenopus
Match: alkbh5 (alkB homolog 5, RNA demethylase [Source:Xenbase;Acc:XB-GENE-987580])

HSP 1 Score: 54.6842 bits (130), Expect = 1.663e-7
Identity = 39/126 (30.95%), Postives = 70/126 (55.56%), Query Frame = 1

Query:  883 GERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVT-RGELINITLYRQPLNLETKIEEAIHNLYK-NGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
             E LT   K++  ++E +  +R +F +D+ G+  T ++KH I+T  G  +N+  YR P      +   I  + + + I + +S +++P++ V  K    IR C DFR+LN V +  A+ MP +DE+
Sbjct:  192 AETLTNSQKQE--MREFLIRNRQIF-SDQPGL--TEMIKHDIITGPGVKVNVRPYRIPEARRQAVAGEIKRMLELDVIEESHSEWSSPIVLV-PKPDGSIRFCNDFRKLNEVSKFDAYPMPRVDEL 311

[Close]

BLAST of KRAB-A domain-containing protein vs. UniProt/SwissProt
Match: sp|P04323|POL3_DROME (Retrovirus-related Pol polyprotein from transposon 17.6 OS=Drosophila melanogaster OX=7227 GN=pol PE=4 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 1.982e-6
Identity = 31/95 (32.63%), Postives = 52/95 (54.74%), Query Frame = 1

Query:  985 THLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNGI-RKCNSPFNTPLICVWEKE----KKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            T+  KH I T+  L   + Y  P   E ++E  I ++   GI R  NSP+N+P+  V +K+    K+  R+ +D+R+LN +       +PN+DE+
Sbjct:  194 TNQTKHTINTKHNLPLYSKYSYPQAYEQEVESQIQDMLNQGIIRTSNSPYNSPIWVVPKKQDASGKQKFRIVIDYRKLNEITVGDRHPIPNMDEI 288

[Close]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Match: A0A5J4NQX1 (Uncharacterized protein OS=Paragonimus westermani OX=34504 GN=DEA37_0008956 PE=4 SV=1)

HSP 1 Score: 84.7297 bits (208), Expect = 1.196e-13
Identity = 66/276 (23.91%), Postives = 127/276 (46.01%), Query Frame = 1

Query:  523 PNVTVKINWEIFECLLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEK---------------ERYQS*DKG*NYICNIEAKFGRQTNDGE----------------RLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVT-RGELINITLYRQPLNLETKIEEAIHNLYKNGI-RKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            P +  K+    FECLLD+G+  +++  + +   +   +    +++   NG  L  +   +  V IG  +  + F VV K+   ++ G  ++I                 ER+            +E + G+    GE                 L   + +  +++++I   R +F  +    GRTH V+H+I T     I     R P++L+ ++E+ + ++ + GI R   SP+ +P++ V +K+   +RLC+D+RQLNAV +  +F +P ID+
Sbjct:  285 PVLKAKVGGRDFECLLDSGSVCSLLDKETYTICQFDAIAGPGSQVLAVNGQPLHILACVRGTVQIGKWTCTLNFFVVPKLPFHVVLGSNYLITMQCILDLPNLAVQVYGERFPLEPVYKTLAGVVEVRTGQHVTKGEVHAEFEWQKFRSTIISHLPAHLAQ--RVRDVIEKHRAIFWWEGQPPGRTHFVRHRIDTGEAHPIRQAARRLPVHLQGQVEQLLTDMLEKGIIRPSTSPWASPVVLV-KKKDGSLRLCVDYRQLNAVTKKDSFPLPRIDD 557

[Close]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Match: A0A0C2MRZ6 (Retrovirus-related Pol polyprotein from transposon 17.6 OS=Thelohanellus kitauei OX=669202 GN=RF11_14197 PE=4 SV=1)

HSP 1 Score: 81.2629 bits (199), Expect = 1.238e-12
Identity = 60/233 (25.75%), Postives = 122/233 (52.36%), Query Frame = 1

Query:  565 LLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRY-ANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEKERYQS*DKG*NYICNIEAKFGRQTNDGERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINIT-LYRQPLNLETKIEEAIHN-LYKNGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            L+DTG  ++++ S+    L    LV+ +  + Y   G  + T+G+  ++V  GD++ E+ F+VV+++  ++I G +++++ +           + + +  + +  N+  +L         L +II++  +VF +     G T L+KH+I+T+      +  YR P +++  I+  I   L K  IR   SP+  P++ V +K+    RLC+DFR+LN V +   + +P  D++
Sbjct:  320 LVDTGACVSLVDSRI---LEHNHLVKPSPLVLYNVTGQLMPTLGQCSLRVAYGDIATEMDFIVVKEINHQVILGRDFIVQNQLVID-------LSSPQLLYKKSNNETLKLCNSFDNTTTLDDIISSFNDVFASSNDDFGFTTLIKHRIITQECTPCCSRPYRVPNHIQLDIQNQISTMLEKKIIRPSKSPWCAPVV-VAKKKDGCNRLCVDFRKLNLVTKRDQYSLPLRDDI 541

[Close]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Match: A0A5S6QD89 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 80.1073 bits (196), Expect = 1.268e-12
Identity = 74/278 (26.62%), Postives = 129/278 (46.40%), Query Frame = 1

Query:  529 VTVKINWEIFECLLDTGTRINVMSSKCFNKLRGQ-KLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEKERYQS*DKG*NYICNIEAKF-------GRQTNDG-------------ERLT*KIKEDC----------KLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIE-----EAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            V V++       L+DTG    ++ S  F ++RGQ KL   N +L  A G+ L+ +G   + + +GD + ++  +VV  +    + G++++  K+     D     + + + K        GR + +G             +R+  ++ E            KL  +++  RN F A ++ +GRT ++KH IVT     NI   R PL     +E     + I  L  N  I   NSP+   ++ V +K+   +RLC+D+R+LN V    A+ +P IDE
Sbjct:   18 VPVQVRNRCIRMLVDTGAGRTLLRSDEFARIRGQWKLSPCNVRLLSAEGTALDVMGSVSLPLQVGDRTFDMEVIVVNALQFAGLLGIDFL--KQHGFVVDLARGTLNSPKQKLRIPLQSAGRTSGNGAWSVSVGKPVSLSKRMLQQLVETTGVPLTASQQKKLHGMLSKFRNAFAASEFDIGRTSVLKHDIVTD----NIRPVRHPLRRLAPVERKEVSQLIQRLLDNKIIEPSNSPWAAGIVPVRKKDGS-LRLCVDYRKLNEVSRRDAYPIPRIDE 288

[Close]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Match: A0A0C2I9X8 (Retrovirus-related Pol polyprotein OS=Thelohanellus kitauei OX=669202 GN=RF11_07929 PE=4 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 1.450e-12
Identity = 60/233 (25.75%), Postives = 122/233 (52.36%), Query Frame = 1

Query:  565 LLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRY-ANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEKERYQS*DKG*NYICNIEAKFGRQTNDGERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINIT-LYRQPLNLETKIEEAIHN-LYKNGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            L+DTG  ++++ S+    L    LV+ +  + Y   G  + T+G+  ++V  GD++ E+ F+VV+++  ++I G +++++ +           + + +  + +  N+  +L         L +II++  +VF +     G T L+KH+I+T+      +  YR P +++  I+  I   L K  IR   SP+  P++ V +K+    RLC+DFR+LN V +   + +P  D++
Sbjct:  319 LVDTGACVSLVDSRI---LEHNHLVKPSPLVLYNVTGQLMPTLGQCSLRVAYGDITSEMDFIVVKEINHQVILGRDFIVQNKLVID-------LSSPQLLYKKSNNETLKLCNSFDNTTTLDDIISSFNDVFASSNDDFGFTTLIKHRIITQECTPCCSRPYRVPNHIQLDIQNQISTMLEKKIIRPSKSPWCAPVV-VAKKKDGCNRLCVDFRKLNLVTKRDQYSLPLRDDI 540

[Close]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Match: A0A5S6Q4F0 (Uncharacterized protein OS=Trichuris muris OX=70415 PE=4 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 8.858e-12
Identity = 74/278 (26.62%), Postives = 129/278 (46.40%), Query Frame = 1

Query:  529 VTVKINWEIFECLLDTGTRINVMSSKCFNKLRGQ-KLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEKERYQS*DKG*NYICNIEAKF-------GRQTNDG-------------ERLT*KIKEDC----------KLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIE-----EAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            V V++       L+DTG    ++ S  F ++RGQ KL   N +L  A G+ L+ +G   + + +GD + ++  +VV  +    + G++++  K+     D     + + + K        GR + +G             +R+  ++ E            KL  +++  RN F A ++ +GRT ++KH IVT     NI   R PL     +E     + I  L  N  I   NSP+   ++ V +K+   +RLC+D+R+LN V    A+ +P IDE
Sbjct:  356 VPVQVRNRCIRMLVDTGAGRTLLRSDEFARIRGQWKLSPCNVRLLSAEGTALDVMGSVSLPLQVGDRTFDMEVIVVNALQFAGLLGIDFL--KQHGFVVDLARGTLNSPKQKLRIPLQSAGRTSGNGAWSVSVGKPVSLSKRMLQQLVETTGVPLTASQRKKLHGMLSKFRNAFAASEFDIGRTSVLKHDIVTD----NIRPVRHPLRRLAPVERKEVSQLIQRLLDNKIIEPSNSPWAAGIVPVRKKDGS-LRLCVDYRKLNEVSRRDAYPIPRIDE 626

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000054058.1 (pep primary_assembly:Astyanax_mexicanus-2.0:19:20158532:20160786:-1 gene:ENSAMXG00000037637.1 transcript:ENSAMXT00000054058.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.7734 bits (151), Expect = 3.514e-10
Identity = 38/117 (32.48%), Postives = 64/117 (54.70%), Query Frame = 1

Query:  907 KEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGEL-INITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            KE  +L+ ++    +VF      +G T  VKH+IV   +  +N+   R P N   ++++ I  L + G I++  S + +P++ V  K    IRLC+D+R+LN   +  AF +P IDE
Sbjct:  239 KEQAELRALLGKYSDVFAVGDDELGYTEKVKHEIVLVDDTPVNLPYRRIPPNQYKEVKDHISQLLRKGVIQESTSSYASPVVVV-RKSDGSIRLCVDYRKLNLKTKRDAFPLPRIDE 354

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000055509.1 (pep primary_assembly:Astyanax_mexicanus-2.0:21:13332550:13338191:1 gene:ENSAMXG00000030987.1 transcript:ENSAMXT00000055509.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 1.492e-9
Identity = 38/126 (30.16%), Postives = 69/126 (54.76%), Query Frame = 1

Query:  883 GERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTR-GELINITLYRQPLNLETKIEEAIHNLYK-NGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            GE LT   +++  LKE +A  R+VF       GRT ++ H+I T  G+++    YR P      +EE +  + +   I    SP+++P++ V + +  + R C DFR+LN++    ++ MP +D++
Sbjct:  889 GEDLTPAQRQE--LKECLARHRSVFSESP---GRTQVIHHRIPTEPGKIVRQRPYRLPEARRKAVEEEVRKMLQLQVIEPSASPWSSPIVLVPKPDGSW-RFCNDFRRLNSISRFDSYPMPRVDDL 1008

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041682.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002320.1:24977:29035:1 gene:ENSAMXG00000038531.1 transcript:ENSAMXT00000041682.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.6102 bits (135), Expect = 3.512e-8
Identity = 37/115 (32.17%), Postives = 64/115 (55.65%), Query Frame = 1

Query:  925 KEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQ-----PLNLETKIEEAIHNLY-KNGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            K+++    +VF  D+  +G THL++H+I     LI+ T  +Q     P +    ++  I  L  +  IR   SP+++P++ V +K    IRLC+D+RQLN+     A+ +P I+E
Sbjct:  290 KDLLQRYSSVFSQDEGELGCTHLIEHEI----PLIDDTPVKQRYRRLPPSQYDLVKGHIQELLDRKVIRASCSPYSSPVVVV-QKRDGTIRLCVDYRQLNSKTRKDAYPLPRIEE 399

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000044431.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000182.1:892613:897532:1 gene:ENSAMXG00000038169.1 transcript:ENSAMXT00000044431.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.225 bits (134), Expect = 5.029e-8
Identity = 38/126 (30.16%), Postives = 70/126 (55.56%), Query Frame = 1

Query:  883 GERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTR-GELINITLYRQPLNLETKIEEAIHNLYKNGI-RKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            G+ LT + K++  L+E++ +   VF +     G+THLV+H I T  G ++    YR P      +E  +  + + GI    +SP+++P++ V + +  + R C DFR+LN V    ++ +P ID++
Sbjct:  726 GQDLTPRQKQE--LRELVDHYTKVFSSLP---GQTHLVQHDIKTPPGFVVRQRPYRLPQARREAVETEVQKMLEMGIIEPSDSPWSSPIVLVPKPDGSW-RFCNDFRRLNKVSAFDSYPIPRIDDL 845

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000041754.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001938.1:55959:59870:1 gene:ENSAMXG00000043385.1 transcript:ENSAMXT00000041754.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.8398 bits (133), Expect = 5.579e-8
Identity = 33/103 (32.04%), Postives = 60/103 (58.25%), Query Frame = 1

Query:  949 NVFMADKWGVGRTHLVKHKIVTRGELINITLYRQ-PLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            N+F   +  +G T L+ H+I    E+     YR+ P +  + ++  I  L  +  IR+ +SPF++P++ V +K+   +RLC+D+RQLNA     ++ +P I+E
Sbjct:  281 NIFAKSEGDLGCTSLISHEIPLLDEVPVRQPYRRIPPSQYSTVKAHIQQLLDSRVIRESSSPFSSPIVLVTKKDGS-LRLCVDYRQLNAKTRRDSYPLPRIEE 382

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000045600.1 (pep primary_assembly:ASM223467v1:4:26167161:26171153:-1 gene:ENSORLG00000023514.1 transcript:ENSORLT00000045600.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 1.236e-9
Identity = 39/117 (33.33%), Postives = 64/117 (54.70%), Query Frame = 1

Query:  919 KLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLN-LETKIEEAIHN-----LYKNGIRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDE 1251
            ++K +++    VF  D   VG T+L+ H+I     L++ T  RQP   +     E  H+     L    IR+ +SP+ +P++ V +K+   +R+C+D+RQLNA     AF +P IDE
Sbjct:  304 RVKALLSKYNRVFAKDDLDVGCTNLMTHEI----PLLDETPVRQPYRRIPPSQYELAHSHIQQLLQSQVIRESSSPYASPIVLV-QKKDGGLRMCVDYRQLNARTRKDAFPLPRIDE 415

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000030651.1 (pep primary_assembly:ASM223467v1:5:21308959:21315033:-1 gene:ENSORLG00000024220.1 transcript:ENSORLT00000030651.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 61.2326 bits (147), Expect = 1.404e-9
Identity = 37/118 (31.36%), Postives = 67/118 (56.78%), Query Frame = 1

Query:  907 KEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKI-VTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            ++  K+ ++   + ++F A     GRT L+ H I +  G  I    YR P  L  ++ + +  + + G I   NS +++P++ V +K+   +R+C+DFR+LNAV E  A+ MP ID++
Sbjct: 1038 EQTTKIMDLFRETPSLFSAQP---GRTTLISHSIRLKDGRPIRQRPYRVPQKLVGRLNDEVRKMLELGVIEPSNSEWSSPVVIVPKKDDS-LRICIDFRKLNAVSEFDAYPMPRIDDL 1151

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000040552.1 (pep primary_assembly:ASM223467v1:6:4563337:4567860:1 gene:ENSORLG00000025739.1 transcript:ENSORLT00000040552.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 2.249e-9
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1

Query:  979 GRTHLVKHKI-VTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            GRT L+ H I +  G  I    YR P  L  ++ + +  + + G I   NS +++P++ V +K+   +R+C+DFR+LNAV E  A+ MP ID++
Sbjct: 1060 GRTTLISHSIRLKDGRPIRQRPYRVPQKLVGRLNDEVRKMLELGVIEPSNSEWSSPVVIVPKKDDS-LRICIDFRKLNAVSEFDAYPMPRIDDL 1152

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000046096.1 (pep primary_assembly:ASM223467v1:13:26491328:26497904:1 gene:ENSORLG00000027568.1 transcript:ENSORLT00000046096.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 2.433e-9
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1

Query:  979 GRTHLVKHKI-VTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            GRT L+ H I +  G  I    YR P  L  ++ + +  + + G I   NS +++P++ V +K+   +R+C+DFR+LNAV E  A+ MP ID++
Sbjct: 1060 GRTTLISHSIRLKDGRPIRQRPYRVPQKLVGRLNDEVRRMLELGVIEPSNSEWSSPVVIVPKKDDS-LRICIDFRKLNAVSEFDAYPMPRIDDL 1152

[Close]

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000038047.1 (pep primary_assembly:ASM223467v1:5:20995901:21001966:-1 gene:ENSORLG00000030265.1 transcript:ENSORLT00000038047.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 2.609e-9
Identity = 37/118 (31.36%), Postives = 67/118 (56.78%), Query Frame = 1

Query:  907 KEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKI-VTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            ++  K+ ++   + ++F A     GRT L+ H I +  G  I    YR P  L  ++ + +  + + G I   NS +++P++ V +K+   +R+C+DFR+LNAV E  A+ MP ID++
Sbjct: 1039 EQTTKIMDLFRETPSLFSAQP---GRTTLISHSIRLKDGRPIRQRPYRVPQKLVGRLNDEVGRMLELGVIEPSNSEWSSPVVIVPKKDDS-LRICIDFRKLNAVSEFDAYPMPRIDDL 1152

[Close]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Match: SMESG000029259.1 (SMESG000029259.1)

HSP 1 Score: 248.054 bits (632), Expect = 1.687e-72
Identity = 131/278 (47.12%), Postives = 184/278 (66.19%), Query Frame = 1

Query:  469 TIDMGQAVEITYSKLQGWPNVTVKINWEIFECLLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEW----------VIEKERYQS*DKG*NYICNIEAKFGRQTNDGERL-----T*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM 1254
            +++  ++  ITY+ +QG P+ T+ I     +CLLDTG RINVM+    ++L   +++ +   LR AN S LET+G+  + V +G M + + F++V+ + PE+I GVE           ++E+   +S     ++IC IEA+FGR   D ERL       K+  + +L EI   ++NVFMADKW +G T+L+KHKI+T+GE I I   RQP+NLE KIEEAI NL  NG IRKCNSP+NTPL+CVW+KEKK IRLCLDFRQLN + E +AF MPN+DE+
Sbjct: 2532 SVEEQKSPAITYNIMQGRPSTTLDIQGRKVDCLLDTGARINVMAKSVIDRLENIEILETRESLRCANNSRLETMGKLNINVKMGSMERNVTFIIVKNLIPEIIGGVELQRLFGIELKCILEEHEKRS-----DFICEIEARFGRIITDEERLRHAIDVLKVTGNKRLLEIFQANKNVFMADKWDIGCTNLIKHKIITKGEPIMIKPRRQPINLEDKIEEAIKNLENNGIIRKCNSPWNTPLVCVWKKEKKDIRLCLDFRQLNKITERQAFPMPNVDEI 2804

[Close]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Match: SMESG000029320.1 (SMESG000029320.1)

HSP 1 Score: 103.99 bits (258), Expect = 1.164e-23
Identity = 76/230 (33.04%), Postives = 119/230 (51.74%), Query Frame = 1

Query:  535 VKINWEIFECLLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRYANGSTLE-TIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEW--VIEKERYQS*DKG*NYICNIEAKF-GRQTNDGERL-----T*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNGIRKCNSPFNTPLICVWEKEKKYIRLCLDFR 1197
            ++IN    E L D+G  I VMS KC+      +L+ S  +L        E  +G  K+        +E+  ++V K+ P+ I GV    +   E  +        + NIE+    ++  D +RL     T K  ++ KL  +I+   N+FMA ++ +G T ++ H+I T G  I     RQP++LE K+EE + NL ++ +RKC SP+NTPL+ V  K    IR+CLDFR
Sbjct:  278 MEINGFHVEMLWDSGASIRVMSEKCW------RLIDSRERLSGVFSKEDEKPLGSVKIFAKWNKKFRELNVIIVRKIHPDFIGGVYTMKIFGMELKE--------VNNIESSLVNKRVTDSDRLKNTLLTLKFDKNSKLGTLISQFSNIFMASRFDLGHTKVITHEIKTSGPPILQNPRRQPMHLEGKVEELVQNLLEDVVRKCQSPWNTPLVIVG-KPDGSIRMCLDFR 492

[Close]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Match: SMESG000081257.1 (SMESG000081257.1)

HSP 1 Score: 102.449 bits (254), Expect = 4.304e-23
Identity = 77/248 (31.05%), Postives = 131/248 (52.82%), Query Frame = 1

Query:  535 VKINWEIFECLLDTGTRINVMSSKCFNKLRGQKLVRSNNKLR--YANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEW--VIEKERYQS*DKG*NYICNIEAKF-GRQTNDGERLT*KI-----KEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNG-IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNI 1245
            ++IN    E L ++G  I+VMS KC+  +    L+ S   L   ++N    + +G  K+        +E+  ++V K+ P  I GV+   +   E  +        + NIE+    ++  D +RL   +      ++ +L  +I+   N+FMA ++ +G T ++ H++ T G  I      QP++LE K+EE + NL + G +RKC SP+NTPL+ V  K    +R+CLDFR LN+V E  +F MP++
Sbjct:  288 MEINGFHVEMLWNSGASISVMSEKCWRLIGSPILMDSRILLSEVFSNEDK-KPLGSVKIVAKWNKKFRELNVIIVRKIHPNFIGGVDTMKIFGMELKE--------VNNIESSLVNKRFTDSDRLKNTLLTLKLDKNSELGTLISQFSNIFMASRFDLGHTKVITHELKTSGPPILQNPRGQPMHLEAKVEELVQNLLEAGVVRKCQSPWNTPLVIVG-KPDGSVRICLDFRLLNSVTEKFSFPMPDM 525

[Close]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Match: SMESG000016546.1 (SMESG000016546.1)

HSP 1 Score: 100.523 bits (249), Expect = 1.161e-22
Identity = 56/96 (58.33%), Postives = 67/96 (69.79%), Query Frame = 1

Query:  841 ICNIEAKFGRQTNDGERLT*KIKE----DCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNGIRK 1116
            +CNI+AKFG+     ER     KE       L EII N++NVFMA+KW +G T L+KHKIVTRG LINI   RQP++LE KIEEAI NL+KNGI K
Sbjct:  113 MCNIDAKFGKLITGTERFDRARKELKVNYTVLAEIIKNNQNVFMANKWEIGCTALLKHKIVTRGSLINIKPRRQPIHLEPKIEEAIQNLFKNGIIK 208

[Close]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Match: SMESG000053025.1 (SMESG000053025.1)

HSP 1 Score: 96.2857 bits (238), Expect = 1.742e-22
Identity = 65/187 (34.76%), Postives = 87/187 (46.52%), Query Frame = 1

Query:  556 FECLLDTGTRINVMSSKCFNKLRGQKLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELIRGVEWVIEKERYQS*DKG*NYICNIEAKFGRQTNDGERLT*KIKEDCKLKEIIANSRNVFMADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNGIRK 1116
             ECLLDTG ++NVMS   F  L+  +L+ + + LR AN   LET  +  ++V I      + F +V  + PE+I                             G+Q                          VFM DKWG+G T L+KHKI T+G+ INI  YRQP+NLE KI+EAI  L+ N I K
Sbjct:    1 MECLLDTGAKVNVMSWSKFENLKDIELIATTDILRCANNFVLETKCKATLEVEINSRKGRVKFPIVAYMTPEVI-----------------------------GKQM-------------------------VFMVDKWGIGCTKLLKHKIETQGKPINIRPYRQPVNLEDKIDEAIKYLWDNDIIK 133

The following BLAST results are available for this feature:

BLAST of KRAB-A domain-containing protein vs. Ensembl Human
BLAST of KRAB-A domain-containing protein vs. Ensembl Celegans
BLAST of KRAB-A domain-containing protein vs. Ensembl Fly
BLAST of KRAB-A domain-containing protein vs. Ensembl Zebrafish
BLAST of KRAB-A domain-containing protein vs. Ensembl Xenopus
BLAST of KRAB-A domain-containing protein vs. Ensembl Mouse
BLAST of KRAB-A domain-containing protein vs. UniProt/SwissProt
BLAST of KRAB-A domain-containing protein vs. TrEMBL
BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
BLAST of KRAB-A domain-containing protein vs. Ensembl Sea Lamprey
BLAST of KRAB-A domain-containing protein vs. Ensembl Yeast
BLAST of KRAB-A domain-containing protein vs. Ensembl Nematostella
BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
BLAST of KRAB-A domain-containing protein vs. Planmine SMEST

BLAST of KRAB-A domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
anxa6	1.043e-8	29.41	annexin A6 [Source:Xenbase;Acc:XB-GENE-989741]	[more]
ENSXETT00000023941.1	1.370e-7	30.70	pep primary_assembly:Xenopus_tropicalis_v9.1:KV463...	[more]
alkbh5	1.663e-7	30.95	alkB homolog 5, RNA demethylase [Source:Xenbase;Ac...	[more]

BLAST of KRAB-A domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1


Match Name	E-value	Identity	Description
sp\|P04323\|POL3_DROME	1.982e-6	32.63	Retrovirus-related Pol polyprotein from transposon...	[more]

BLAST of KRAB-A domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5J4NQX1	1.196e-13	23.91	Uncharacterized protein OS=Paragonimus westermani ...	[more]
A0A0C2MRZ6	1.238e-12	25.75	Retrovirus-related Pol polyprotein from transposon...	[more]
A0A5S6QD89	1.268e-12	26.62	Uncharacterized protein OS=Trichuris muris OX=7041...	[more]
A0A0C2I9X8	1.450e-12	25.75	Retrovirus-related Pol polyprotein OS=Thelohanellu...	[more]
A0A5S6Q4F0	8.858e-12	26.62	Uncharacterized protein OS=Trichuris muris OX=7041...	[more]

BLAST of KRAB-A domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000054058.1	3.514e-10	32.48	pep primary_assembly:Astyanax_mexicanus-2.0:19:201...	[more]
ENSAMXT00000055509.1	1.492e-9	30.16	pep primary_assembly:Astyanax_mexicanus-2.0:21:133...	[more]
ENSAMXT00000041682.1	3.512e-8	32.17	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000044431.1	5.029e-8	30.16	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000041754.1	5.579e-8	32.04	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of KRAB-A domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of KRAB-A domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000045600.1	1.236e-9	33.33	pep primary_assembly:ASM223467v1:4:26167161:261711...	[more]
ENSORLT00000030651.1	1.404e-9	31.36	pep primary_assembly:ASM223467v1:5:21308959:213150...	[more]
ENSORLT00000040552.1	2.249e-9	36.17	pep primary_assembly:ASM223467v1:6:4563337:4567860...	[more]
ENSORLT00000046096.1	2.433e-9	36.17	pep primary_assembly:ASM223467v1:13:26491328:26497...	[more]
ENSORLT00000038047.1	2.609e-9	31.36	pep primary_assembly:ASM223467v1:5:20995901:210019...	[more]

BLAST of KRAB-A domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000029259.1	1.687e-72	47.12	SMESG000029259.1	[more]
SMESG000029320.1	1.164e-23	33.04	SMESG000029320.1	[more]
SMESG000081257.1	4.304e-23	31.05	SMESG000081257.1	[more]
SMESG000016546.1	1.161e-22	58.33	SMESG000016546.1	[more]
SMESG000053025.1	1.742e-22	34.76	SMESG000053025.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30025997 ID=SMED30025997|Name=KRAB-A domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1255bp
CTTTTTTATTGGCGGCTCCTTATATATATTTATTAAACTCATGAAAATCG
GTCATAAGATTTTCTTAATTAGTTTTCAAATTTATTCGTTTTTCTAGGCT
TTCAATTTTTAATTAATACTTTAAAATGCATCAAGTTTGGATTTAATATA
TATTAACACTAGGAAGACCAAAAGATTTAAACACTATAAATACCAGGTAA
AAAAGCGCCAAAATGTTTTGGTTGTGGGAAAAGGGCATATAAGAAGGTTA
TGCCAGGAAATTAGGTGTAAAAATGCAACAGAAATGGTAATAGAGCAGAA
GAATTTTATACAAGGTTGAGTCACAGAGGAACAATAGAGGAGTTGGTTGG
AGACGTATATTACCACAGGAGTTGATGAGATATCCTCAGGGGGCCGAAAA
GTGGGATAATGTAGGAAAGGTAAGCGAGAAAGTGTACAAATTCCTAAGGA
GAGATAGAAAGATTTGAAACGATTGATATGGGACAGGCTGTAGAAATTAC
GTATAGCAAGCTGCAAGGATGGCCGAATGTAACAGTAAAAATAAATTGGG
AAATTTTCGAGTGTCTATTAGACACAGGGACAAGAATCAATGTGATGAGT
TCGAAGTGTTTTAACAAATTGAGAGGACAAAAATTGGTGAGAAGCAATAA
CAAGTTACGTTACGCAAACGGGAGTACGTTGGAGACAATCGGGAGAACCA
AAGTACAAGTAACCATTGGAGATATGTCTAAGGAAATTATATTTGTTGTG
GTAGAAAAAGTGGCACCAGAATTGATTAGAGGAGTGGAATGGGTTATCGA
AAAGGAAAGATATCAAAGTTAGGACAAAGGATAGAACTATATCTGTAATA
TTGAAGCAAAATTTGGCAGACAGACAAATGATGGTGAACGGTTGACATAA
AAGATAAAGGAAGATTGCAAGTTAAAAGAAATTATTGCGAACAGTAGAAA
CGTGTTTATGGCCGATAAATGGGGAGTGGGGCGCACGCATCTGGTAAAAC
ATAAAATTGTGACAAGAGGAGAACTGATTAACATTACACTATATCGTCAA
CCATTAAACTTGGAAACAAAAATAGAAGAAGCAATACATAATTTATACAA
AAATGGCATACGAAAATGCAACTCCCCGTTTAACACACCACTAATATGCG
TATGGGAAAAAGAGAAAAAATACATAAGACTTTGTCTGGATTTTAGACAG
TTGAACGCAGTAATGGAGAGCCGGGCATTTCTAATGCCAAACATAGACGA
GATGT

protein sequence of SMED30025997-orf-1

>SMED30025997-orf-1 ID=SMED30025997-orf-1|Name=SMED30025997-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=115bp
MGQAVEITYSKLQGWPNVTVKINWEIFECLLDTGTRINVMSSKCFNKLRG
QKLVRSNNKLRYANGSTLETIGRTKVQVTIGDMSKEIIFVVVEKVAPELI
RGVEWVIEKERYQS*

protein sequence of SMED30025997-orf-2

>SMED30025997-orf-2 ID=SMED30025997-orf-2|Name=SMED30025997-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=99bp
MADKWGVGRTHLVKHKIVTRGELINITLYRQPLNLETKIEEAIHNLYKNG
IRKCNSPFNTPLICVWEKEKKYIRLCLDFRQLNAVMESRAFLMPNIDEM

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0015074	DNA integration
GO:0006508	proteolysis

Vocabulary: **INTERPRO**
Term	Definition
IPR021109	Peptidase_aspartic_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0003676	nucleic acid binding
GO:0004190	aspartic-type endopeptidase activity
GO:0008270	zinc ion binding

Main menu

KRAB-A domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Owlery

blazegraph-runner