Fzd-5/8-2

Overview
NameFzd-5/8-2
Smed IDSMED30025972
Length (bp)2144
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Fzd-5/8-2 (SMED30025972) t-SNE clustered cells

Violin plots show distribution of expression levels for Fzd-5/8-2 (SMED30025972) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Fzd-5/8-2 (SMED30025972) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Fzd-5/8-2 (SMED30025972) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025972

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 12

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30025972SMESG000053774.1 SmedASXL_008196SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30025972SMESG000053774.1 SmedASXL_060150SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30025972SMESG000053774.1 dd_Smed_v4_17168_1_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30025972SMESG000053774.1 dd_Smed_v6_17168_1_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
pharynxSMED30025972SMESG000053774.1 Contig52925newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
pharynxSMED30025972SMESG000053774.1 Contig52925uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30025972SMESG000053774.1 Contig52925newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
neuronSMED30025972SMESG000053774.1 Contig52925uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30025972SMESG000053774.1 Contig52925newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30025972SMESG000053774.1 Contig52925uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
protonephridiaSMED30025972SMESG000053774.1 Contig28401newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
head regionSMED30025972SMESG000053774.1 OX_Smed_1.0.09619ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Human
Match: FZD8 (frizzled class receptor 8 [Source:HGNC Symbol;Acc:HGNC:4046])

HSP 1 Score: 175.252 bits (443), Expect = 1.059e-45
Identity = 122/407 (29.98%), Postives = 193/407 (47.42%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVC------------------------------FQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ + S  HP YN+V TG +ANCA PC +PF   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+++RLVAGH +  C                                        ++   +R++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN +  +L  F+LAPL ++   G  FL  GF+S+ R                 R++       +    L KL          G   ++ ++P  +    + YE   R  WE    C CL  +Q +     P   +++LKY     +GI  G W+W  +T  SW
Sbjct:  231 GCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID-MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRI----------------RSVIKQQDGPTKTHKLEKLMIR------LGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQ-ARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW 613
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Human
Match: FZD5 (frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043])

HSP 1 Score: 169.088 bits (427), Expect = 5.012e-44
Identity = 120/376 (31.91%), Postives = 182/376 (48.40%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            CKCR P + I    HP YNKV TG + NCA PC  P    +       W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+GF++RLV GH    C +  +          + ++ + P++C+I FL  YFF  AS +WW +L LTWF   G+ W +  I  Y+Q +H  AW  P + S+ AL +S+VDGDPV G+C VGN N   L  F+L PL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   L+ ++P  +     +YE  +R  WE A TC C     +      P   + +LKY     +GI  G WIW  +T  SW
Sbjct:  190 CKCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSADERTFATFWIGLWSVLCFISTSTTVATFLID-MERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNH---------IHYETTGPALCTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGH-DTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESW 530
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Human
Match: FZD2 (frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040])

HSP 1 Score: 97.4413 bits (241), Expect = 1.818e-20
Identity = 113/394 (28.68%), Postives = 171/394 (43.40%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCR------SPFIENNRYNLIPLW-LSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLNQIQSNSYIP--TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDT 1595
            P Y      G  +CA PC       S F          LW L+ SV    +CC S+  T     V++   + P R + ++  C   +SV +I   V    R VC +  S+    +++     Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P + ++  L M  +DGD ++G+C VG  +   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L +L          G   ++ ++P  +      YE  +R HWE   ++  C  L       Y P  +P   +Y++KY     +GI  G WIW  +T +SW     RL    T +R+ +T
Sbjct:  208 PSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSV----LCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQE-RVVCNERFSEDGYRTVV-----QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLERLMVR------IGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL----TNSRHGET 563
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Human
Match: FZD1 (frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038])

HSP 1 Score: 92.8189 bits (229), Expect = 7.803e-19
Identity = 110/386 (28.50%), Postives = 164/386 (42.49%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFV----CCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLN----QIQSNSYIP-----TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            P Y   H  G  +C  PC    +    Y   P  L  S   I +    CC S+L T +   V++     P R + ++  C   ++V +I   +    R VC   + K  +D    +   Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P I ++  L +  VDGD ++G+C VG  N   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R  WE   +A +C         +Q+    P     +P   ++++KY     +GI  G WIW  +T NSW     RL
Sbjct:  283 PSYLNYHFLGEKDCGAPCEPTKVYGLMY-FGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLL-EDRVVC---NDKFAEDGARTVA--QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGVFSVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 637
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Human
Match: FZD3 (frizzled class receptor 3 [Source:HGNC Symbol;Acc:HGNC:4041])

HSP 1 Score: 88.9669 bits (219), Expect = 1.153e-17
Identity = 105/416 (25.24%), Postives = 176/416 (42.31%), Query Frame = 3 
Query:  333 IDFDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISS----LLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFF--YGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCT-----CLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            +D +    PT      +     FWC  +     +KID      Y+ +H   + +C+ PC + +      +    +    +GLI + C+S+     LTF+++ V   + P R + +   C + +S+ F I  +    R  C        + S +     Q S    C++ F+  YFF  A  +WW +L +TWF      W S  I+K + L+H  AW  PG  +++ L M+ ++GD ++G+C VG  +   L  F+LAPLC++   G   L  G +        S NR ++ IP                  L K     + KF    G   ++  +PL +  G   YE  +R  WE   +   C      C  Q+   S    P ++L+++KY     +GI    W+   +T   W
Sbjct:  141 VDLNLAGEPTEGAPVAVQRDYGFWCPRE-----LKIDP--DLGYSFLH---VRDCSPPCPNMYFRREELSFARYF----IGLISIICLSATLFTFLTFLID-VTRFRYPERPIIFYAVCYMMVSLIFFIGFLLED-RVACNASIPAQYKASTVT----QGSHNKACTMLFMILYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVDALRYFVLAPLCLYVVVGVSLLLAGII--------SLNRVRIEIP------------------LEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGIWETTWIQERCREYHIPCPYQVTQMS---RPDLILFLMKYLMALIVGIPSVFWVGSKKTCFEW 507
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Match: cfz-2 (Frizzled-2 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ2])

HSP 1 Score: 111.694 bits (278), Expect = 2.288e-25
Identity = 123/424 (29.01%), Postives = 192/424 (45.28%), Query Frame = 3 
Query:  405 CNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFV--LNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQ------QLYNTN 1652
            C C C  P   + S       K   G + NCA+ C SP +  + ++L+  W++        CC+ +  TF+  L   +  Q P R +  +  CQ+ ++VGF+IR   GH    C   DS  I+ +        +++ S+C + FL TYFF  A+ +WW +L LTW  +    WS   I  +S  +H + W  P I ++L +  +A+DGDP+TG+C VGN + Q    F+L PL V+   G  FL  GF     C+  S         +         S+ESA        T  ++K   G   L+ +IP  L    + YE   RS WE +  C+C         I   S+++ ++K      +G   G W+   +T +SW  +I     C   +R   +  K +P  I  A+      Q YNT+
Sbjct:  193 CQCTCNQPFQFVAS------EKSKVGNVTNCAYSCHSPALAES-HSLVSNWMAF---WSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIAC---DSMRIKGA-------DDNSGSLCFVVFLLTYFFGMAASVWWVILSLTWVLSAASKWSPEAISSFSFHFHVVGWCLPAIQTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGF-----CNLWS---------IRNEVQKQHPSLESAHK-----ITQLMSKI--GIFSLLYTIPSLLIICVLFYEQNHRSLWEQSQLCSC----SPKQTIGDSSLIISLIKTCCMCILGWTSGFWVCSTKTLSSWKNAIC----CLGSSR---SLPKYQPADILYAKSDMSSSQFYNTS 564
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9970037:1 gene:WBGene00003397.1 transcript:T23D8.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5)

HSP 1 Score: 73.559 bits (179), Expect = 2.529e-13
Identity = 93/374 (24.87%), Postives = 152/374 (40.64%), Query Frame = 3 
Query:  477 TGGLANCAWPCRS----PFIENNRYN-LIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEM----RWRSHW-----------ELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            +G L  C+  C +    P + + R   ++ +W +      FVC + +L+TF+++      P  R + Y+  C + +S  ++I +V G     C    S P        L  Q      CS   +  YFFF +S  WW +LCL WF    L W +  I   S  +H + W  P + S+  L  ++VDGD  TG+C VGN+N   L+ F   P+ V               ++ C   S  R +  I +          VE   S L KL          G   ++ S+P  +    + Y+      W   W           EL      ++    +  +  P I++++LKY     +GI C  W+   +T +S+
Sbjct:  201 SGRLPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPV-RPILYLAFCYLAISTVYMIGVV-GEDGFACGTYGSTPTT------LVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVV--------SLALGAVLLVCGIWSMIRIRSYIKLQ------HADVERNISKLEKLMLR------IGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGWLHHRCVRLQDRELFGFTYPVDDCPMDPKVAAPEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSY 546
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9969413:1 gene:WBGene00003397.1 transcript:T23D8.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5)

HSP 1 Score: 73.559 bits (179), Expect = 2.654e-13
Identity = 93/374 (24.87%), Postives = 152/374 (40.64%), Query Frame = 3 
Query:  477 TGGLANCAWPCRS----PFIENNRYN-LIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEM----RWRSHW-----------ELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            +G L  C+  C +    P + + R   ++ +W +      FVC + +L+TF+++      P  R + Y+  C + +S  ++I +V G     C    S P        L  Q      CS   +  YFFF +S  WW +LCL WF    L W +  I   S  +H + W  P + S+  L  ++VDGD  TG+C VGN+N   L+ F   P+ V               ++ C   S  R +  I +          VE   S L KL          G   ++ S+P  +    + Y+      W   W           EL      ++    +  +  P I++++LKY     +GI C  W+   +T +S+
Sbjct:  199 SGRLPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPV-RPILYLAFCYLAISTVYMIGVV-GEDGFACGTYGSTPTT------LVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVV--------SLALGAVLLVCGIWSMIRIRSYIKLQ------HADVERNISKLEKLMLR------IGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGWLHHRCVRLQDRELFGFTYPVDDCPMDPKVAAPEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSY 544
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Match: lin-17 (Transmembrane receptor LIN-17 [Source:UniProtKB/TrEMBL;Acc:G5EDV1])

HSP 1 Score: 52.373 bits (124), Expect = 9.712e-7
Identity = 95/380 (25.00%), Postives = 152/380 (40.00%), Query Frame = 3 
Query:  417 CRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFI---ENNRY-NLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAP--LCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            C S ++ +D    P+  K H      CA+ C+S  +   +N R      +W + +   +    + S LTF ++R +  + P R V Y+  C    S+ ++  L        C    +     S L +  F NS    C  SFL  YFF  A+ LWW +   T + + G  W    I+  S   HF+AW    + +++ L  + VD   +T LC VGN+N   L+ F++ P  +C+   + F   G           +S  R ++S     RT  TDT      S L KL          GF   +  +P  +      Y+    + W    T  C  Q  +      P   +Y+       A G  C  W+   +T ++W
Sbjct:  170 CPSDLVDVD----PHDPKSH------CAFACQSNVMFSTDNKRMVRSWSIWFAAANAGV---ALFSFLTFAIDR-KRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNG---RSYLSIGTFDNS---YCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGF----------ASMCRERISF----RTRGTDT------SKLEKLMVK------MGFFCALFILPNVIELVCQCYKFMILTQWT-RMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAW 502
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Match: lin-17 (Transmembrane receptor LIN-17 [Source:UniProtKB/TrEMBL;Acc:G5EDV1])

HSP 1 Score: 52.373 bits (124), Expect = 9.712e-7
Identity = 95/380 (25.00%), Postives = 152/380 (40.00%), Query Frame = 3 
Query:  417 CRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFI---ENNRY-NLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAP--LCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            C S ++ +D    P+  K H      CA+ C+S  +   +N R      +W + +   +    + S LTF ++R +  + P R V Y+  C    S+ ++  L        C    +     S L +  F NS    C  SFL  YFF  A+ LWW +   T + + G  W    I+  S   HF+AW    + +++ L  + VD   +T LC VGN+N   L+ F++ P  +C+   + F   G           +S  R ++S     RT  TDT      S L KL          GF   +  +P  +      Y+    + W    T  C  Q  +      P   +Y+       A G  C  W+   +T ++W
Sbjct:  170 CPSDLVDVD----PHDPKSH------CAFACQSNVMFSTDNKRMVRSWSIWFAAANAGV---ALFSFLTFAIDR-KRFRFPERCVFYLSLCIFISSLPYLTPLFIDAPIRSCHALGNG---RSYLSIGTFDNS---YCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGF----------ASMCRERISF----RTRGTDT------SKLEKLMVK------MGFFCALFILPNVIELVCQCYKFMILTQWT-RMTIDCKQQSGACHRPTPPQAEIYMTAVISSLATGFSCLMWVLSAKTVHAW 502
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0112890)

HSP 1 Score: 169.088 bits (427), Expect = 8.036e-44
Identity = 135/421 (32.07%), Postives = 199/421 (47.27%), Query Frame = 3 
Query:  405 CNCKCRSPMI------------KIDSVHHPYY-----NKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPP 1616
            C+C CRSP+I            ++  +HHP++           G+ NC  PC+ PF  N+  +   LW+++  GL F   + +L TF+++  E  + P R + ++  C   ++VG++ R    +    C         D LLL  R  ++ P  C++ FL TYFF  AS +WW +L  TWF   GL W +  I K+SQ +H  AW  P + S+  L +SAVDGDP+ G+C VGN+N  HL TF+LAPL V+   G  FL  GF+S+ R       +  +   V              A  L KL          G   ++ ++P  +  G  +YE  +   W  A  C C  Q++     P  S+L+  LKY    A+GI  G WIW  +T  SW     RLL    +T       K +PP
Sbjct:  253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIID-TERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC---------DGLLL--RESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK-------------ADKLEKLMIR------IGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPC-AQVKGPGKKPLYSVLM--LKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPP 639
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0075029)

HSP 1 Score: 169.088 bits (427), Expect = 8.036e-44
Identity = 135/421 (32.07%), Postives = 199/421 (47.27%), Query Frame = 3 
Query:  405 CNCKCRSPMI------------KIDSVHHPYY-----NKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPP 1616
            C+C CRSP+I            ++  +HHP++           G+ NC  PC+ PF  N+  +   LW+++  GL F   + +L TF+++  E  + P R + ++  C   ++VG++ R    +    C         D LLL  R  ++ P  C++ FL TYFF  AS +WW +L  TWF   GL W +  I K+SQ +H  AW  P + S+  L +SAVDGDP+ G+C VGN+N  HL TF+LAPL V+   G  FL  GF+S+ R       +  +   V              A  L KL          G   ++ ++P  +  G  +YE  +   W  A  C C  Q++     P  S+L+  LKY    A+GI  G WIW  +T  SW     RLL    +T       K +PP
Sbjct:  253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIID-TERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC---------DGLLL--RESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK-------------ADKLEKLMIR------IGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPC-AQVKGPGKKPLYSVLM--LKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPP 639
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0332735)

HSP 1 Score: 169.088 bits (427), Expect = 8.036e-44
Identity = 135/421 (32.07%), Postives = 199/421 (47.27%), Query Frame = 3 
Query:  405 CNCKCRSPMI------------KIDSVHHPYY-----NKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPP 1616
            C+C CRSP+I            ++  +HHP++           G+ NC  PC+ PF  N+  +   LW+++  GL F   + +L TF+++  E  + P R + ++  C   ++VG++ R    +    C         D LLL  R  ++ P  C++ FL TYFF  AS +WW +L  TWF   GL W +  I K+SQ +H  AW  P + S+  L +SAVDGDP+ G+C VGN+N  HL TF+LAPL V+   G  FL  GF+S+ R       +  +   V              A  L KL          G   ++ ++P  +  G  +YE  +   W  A  C C  Q++     P  S+L+  LKY    A+GI  G WIW  +T  SW     RLL    +T       K +PP
Sbjct:  253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIID-TERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC---------DGLLL--RESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK-------------ADKLEKLMIR------IGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPC-AQVKGPGKKPLYSVLM--LKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPP 639
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0330194)

HSP 1 Score: 169.088 bits (427), Expect = 8.036e-44
Identity = 135/421 (32.07%), Postives = 199/421 (47.27%), Query Frame = 3 
Query:  405 CNCKCRSPMI------------KIDSVHHPYY-----NKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPP 1616
            C+C CRSP+I            ++  +HHP++           G+ NC  PC+ PF  N+  +   LW+++  GL F   + +L TF+++  E  + P R + ++  C   ++VG++ R    +    C         D LLL  R  ++ P  C++ FL TYFF  AS +WW +L  TWF   GL W +  I K+SQ +H  AW  P + S+  L +SAVDGDP+ G+C VGN+N  HL TF+LAPL V+   G  FL  GF+S+ R       +  +   V              A  L KL          G   ++ ++P  +  G  +YE  +   W  A  C C  Q++     P  S+L+  LKY    A+GI  G WIW  +T  SW     RLL    +T       K +PP
Sbjct:  253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIID-TERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC---------DGLLL--RESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK-------------ADKLEKLMIR------IGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPC-AQVKGPGKKPLYSVLM--LKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPP 639
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0075028)

HSP 1 Score: 169.088 bits (427), Expect = 8.036e-44
Identity = 135/421 (32.07%), Postives = 199/421 (47.27%), Query Frame = 3 
Query:  405 CNCKCRSPMI------------KIDSVHHPYY-----NKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPP 1616
            C+C CRSP+I            ++  +HHP++           G+ NC  PC+ PF  N+  +   LW+++  GL F   + +L TF+++  E  + P R + ++  C   ++VG++ R    +    C         D LLL  R  ++ P  C++ FL TYFF  AS +WW +L  TWF   GL W +  I K+SQ +H  AW  P + S+  L +SAVDGDP+ G+C VGN+N  HL TF+LAPL V+   G  FL  GF+S+ R       +  +   V              A  L KL          G   ++ ++P  +  G  +YE  +   W  A  C C  Q++     P  S+L+  LKY    A+GI  G WIW  +T  SW     RLL    +T       K +PP
Sbjct:  253 CSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIID-TERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIAC---------DGLLL--RESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVK-------------ADKLEKLMIR------IGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPC-AQVKGPGKKPLYSVLM--LKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPP 639
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Match: fzd8b (frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GENE-000328-4])

HSP 1 Score: 188.734 bits (478), Expect = 2.679e-51
Identity = 123/393 (31.30%), Postives = 197/393 (50.13%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRN 1586
             C CR+PM+ + S HHP YN+V TG + NCA PC +P++          W+ I   L F+   ++++TF+++ +E  + P R + ++  C + +S+G+IIRL+AGH R  C Q       +  +  + ++ + P++C++ FL  YFF  AS +WW +L  TWF   GL W +  I +YSQ +H  AW  P + S+  L +S+VDGD + G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    +     G   ++ ++   +     VYE   R  WE+A  C C     S+   P P   +++LKY     +GI  G W W  +T +SW     R   C+  T+ 
Sbjct:  185 ECYCRAPMVPVHSDHHPLYNRVKTGQIPNCAMPCHNPYLSQEERTFATFWIGIWSVLCFLSTFATVITFLID-IERFKYPERPIIFLSACYMFVSLGYIIRLIAGHERVACNQ-------NHEVDHIHYETTGPALCTLVFLLIYFFGMASAIWWVILSFTWFLAAGLKWGNEAIARYSQYFHMAAWLIPSVKSITVLALSSVDGDSIAGICYVGNQNLDNLRGFVLAPLVIYLFIGTIFLFAGFVSMFR---------------------IRSVIKQGGTKTDKLERLMVR---IGVFTVLYTVVAIMIVACYVYEHHNREAWEIAHACNC----SSDKKAPKPDYAVFMLKYFMCLLIGITSGAWTWSSKTLDSWRALCTRCCCCRWATKG 541
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Match: fzd8b (frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GENE-000328-4])

HSP 1 Score: 187.578 bits (475), Expect = 7.683e-51
Identity = 123/393 (31.30%), Postives = 196/393 (49.87%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRN 1586
             C CR+PM+ + S HHP YN+V TG + NCA PC +P++          W+ I   L F+   +++ TF+++ +E  + P R + ++  C + +S+G+IIRL+AGH R  C Q       +  +  + ++ + P++C++ FL  YFF  AS +WW +L  TWF   GL W +  I +YSQ +H  AW  P + S+  L +S+VDGD + G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    +     G   ++ ++   +     VYE   R  WE+A  C C     S+   P P   +++LKY     +GI  G W W  +T +SW     R   C+  T+ 
Sbjct:  185 ECYCRAPMVPVHSDHHPLYNRVKTGQIPNCAMPCHNPYLSQEERTFATFWIGIWSVLCFLSTFATVATFLID-IERFKYPERPIIFLSACYMFVSLGYIIRLIAGHERVACNQ-------NHEVDHIHYETTGPALCTLVFLLIYFFGMASAIWWVILSFTWFLAAGLKWGNEAIARYSQYFHMAAWLIPSVKSITVLALSSVDGDSIAGICYVGNQNLDNLRGFVLAPLVIYLFIGTIFLFAGFVSMFR---------------------IRSVIKQGGTKTDKLERLMVR---IGVFTVLYTVVAIMIVACYVYEHHNREAWEIAHACNC----SSDKKAPKPDYAVFMLKYFMCLLIGITSGAWTWSSKTLDSWRALCTRCCCCRWATKG 541
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Match: fzd5 (frizzled class receptor 5 [Source:ZFIN;Acc:ZDB-GENE-990415-218])

HSP 1 Score: 187.578 bits (475), Expect = 1.100e-50
Identity = 132/421 (31.35%), Postives = 208/421 (49.41%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTS 1670
             C CR P++ I    HP +N+V+TG L NCA PC  P+   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +S+G+I+RL+AGH R  C   +    Q  +L    +  + P++C++ FL  YFF  AS +WW +L  TWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN + + L  F+LAPL V+  +G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +    +VYE  +R  WE A  C+C ++ Q       P   +++LKY     +GI  G WIW  +T  SW   I R + C+T+          KPP    A  +Y+   T  T+
Sbjct:  199 ECHCRGPLVPIKKEAHPLHNRVNTGSLPNCALPCHQPYFSQDERTFTTFWIGLWSVLCFVSTFTTVATFLID-MERFKYPERPIIFLAACYLFVSLGYIVRLLAGHERVAC---EGTGDQQHIL----YDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLEGLRGFVLAPLVVYLFTGSLFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGLFTVLYTVPATIVVACLVYEQHYRPSWERALACSCPSERQRLGM--GPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRRFIARYVPCRTR----------KPP--VSASSMYSEASTALTA 573
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 178.333 bits (451), Expect = 1.409e-47
Identity = 117/377 (31.03%), Postives = 193/377 (51.19%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ ++S  HP YN+V TG + NCA PC +P+   +       W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+G+I+RL+AGH +  C +       +  +  + ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE+   C+CL + +    I  P   +++LKY     +GI  G W W  +T  SW
Sbjct:  192 GCQCRAPMVPVNSDRHPLYNRVKTGQIPNCAMPCHNPYFTQDERTFTAFWIGLWSVLCFISTFATVATFLID-MERFKYPERPIIFLSACYMFVSIGYIVRLIAGHEKVACNR-------EYDVEHIHYETTGPALCTVVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLIPSMKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTVLYTVPATIIVACYFYEQHNRQSWEITHNCSCLLEQE----IKRPDYAVFMLKYFMCLLVGITSGVWTWSGKTLESW 532
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223])

HSP 1 Score: 94.7449 bits (234), Expect = 8.981e-20
Identity = 106/384 (27.60%), Postives = 162/384 (42.19%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSP------FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHY---RTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQ----SNSYIP-TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            P Y K H  G  +C  PC         +          LW+ I      +CC+S+L T +   V++   + P R + ++  C   ++V +     AG +   + VC    S     ++      Q +    C+I F+  YFF  AS +WW +L LTWF + G+ W    I+  SQ +H  AW  P + ++  L M  VDGD +TG+C VG  N   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R  WE         +       N++ P +P   ++++KY     +GI  G WIW  +T  SW     RL
Sbjct:  202 PTYLKYHFMGEKDCGAPCEPTRPNGLMYFREEEVKFGRLWVGI---WSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAY----AAGFFLEDKVVCIDKFSDDGYKTVA-----QGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDMLTGVCYVGIYNVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHMQTCKRFAVPCPVNNFAPMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL 549
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Match: zdhhc9 (zinc finger DHHC-type containing 9 [Source:Xenbase;Acc:XB-GENE-1016830])

HSP 1 Score: 177.948 bits (450), Expect = 1.835e-47
Identity = 116/376 (30.85%), Postives = 185/376 (49.20%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            CKCR P + I    HP YN++ TG + NCA PC  P+   +       W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+G+I+RL+ GH    C +             + ++ + P++C++ FL  YFF  AS +WW +L  TWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL V+  +G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +     +YE  +R HWE A  C+C    +       P   +++LKY     +GI  G WIW  +T  SW
Sbjct:  177 CKCREPFLSITRESHPLYNRIKTGQVPNCAMPCFQPYFTQDEKTFATFWIGLWSILCFISTFTTVATFLID-MERFRYPERPIIFLSACYLFVSIGYIVRLIVGHENVACNKDH-----------IHYETTGPALCTVVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVVYLFTGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFSVLYTVPATIVVACYIYEQHYREHWEKAHNCSCPGDKKRYR----PDYAVFMLKYFMCLVVGITSGVWIWSGKTLESW 512
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Match: fzd8 (frizzled class receptor 8 [Source:NCBI gene;Acc:100038274])

HSP 1 Score: 173.326 bits (438), Expect = 1.153e-45
Identity = 120/384 (31.25%), Postives = 190/384 (49.48%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIP-TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVR 1556
             C+CR+PM+ + +  HP YN+V TG + NCA PC +P+           W+ +   L F    +++ TF+++ +E  + P R + ++  C + +S G+++RL+AGH +  C + +       L  ++ ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P I S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE+A  C   N  Q     P  P   +++LKY     +GI  G WIW  +T  SW     R
Sbjct:  189 GCQCRAPMVPVTNERHPLYNRVRTGQIPNCAMPCHNPYFSPEERTFTEFWIGLWSVLCFASTFATVSTFLID-MERFKYPERPIIFLSACYLLVSAGYLVRLIAGHEKVACSRGEL-----DLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNC---NSCQPEVAQPRRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTR 539
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Match: ntrk1 (neurotrophic receptor tyrosine kinase 1 [Source:Xenbase;Acc:XB-GENE-923001])

HSP 1 Score: 99.7525 bits (247), Expect = 2.916e-21
Identity = 109/381 (28.61%), Postives = 164/381 (43.04%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSP------FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLNQIQSNSYIP--TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            P Y      G  +CA PC         F   +      +W+ I   L   CC S+  T     V++   + P R + ++  C   +SV +I   V G  + VC +  S+    +++     Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P + ++  L M  +DGD ++G+C VG  N   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L +L          G   ++ ++P  +      YE  +R HWE   ++  C  L       Y P  TP   +Y++KY     +GI  G WIW  +T +SW     RL
Sbjct:  196 PSYLNYRFLGEKDCAAPCEPSKNDGFMFFSQDEIRFARVWILIWSVL---CCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLGD-KVVCNENFSEDGYKTVV-----QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNNIDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLERLMVR------IGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQNCKSLAIPCPLQYTPRMTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 543
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Match: drg1 (developmentally regulated GTP binding protein 1 [Source:Xenbase;Acc:XB-GENE-980752])

HSP 1 Score: 86.6557 bits (213), Expect = 5.919e-17
Identity = 101/418 (24.16%), Postives = 175/418 (41.87%), Query Frame = 3 
Query:  333 IDFDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKID-SVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISS----LLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFF--YGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIP---------TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            +D       T E    +     FWC  +     +KID  + + +       G+ +C+ PC   +      +    +    +G+I + C+S+     LTF+++ V   + P R + +   C + +S+ F I  +    +  C   +    + + +     Q S    C++ F+  YFF  A  +WW +L +TWF      W S  I+K + L+H  AW  PG  +++ L M+ ++GD ++G+C VG  + Q L  F+LAPLC+    G   L  G +        S NR ++ IP                  L K     + KF    G   ++  +PL +  G   YE  +R  WE     T + +     +IP          P ++L+++KY     +GI    W+   +T   W
Sbjct:  140 VDISLSGDVTEETPLAVQRDYGFWCPRE-----LKIDPDLGYSFL------GVRDCSPPCPHMYFRREELSFARYF----IGVISIVCLSATLFTFLTFLID-VTRFRYPERPIIFYAVCYMMVSLIFFIGFLLED-KVACNGANPSQYKAATVT----QGSHNKACTMLFMVLYFFTMAGSVWWVILTITWFLAAVPKWGSEAIEKKALLFHASAWGIPGTLTIILLAMNKIEGDNISGVCFVGLYDVQALRYFVLAPLCLDVVVGVSLLLAGII--------SLNRVRIEIP------------------LEKENQDKLVKFMIRIGVFSILYLVPLLVVIGCYFYEQAYRGVWE----TTWVQERCKEYHIPCPYKVTQTSRPDLILFLMKYLMALVVGIPSVFWVGSKKTCFEW 506
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Match: FZD4 (frizzled class receptor 4 [Source:NCBI gene;Acc:100497693])

HSP 1 Score: 85.5001 bits (210), Expect = 9.871e-17
Identity = 97/355 (27.32%), Postives = 160/355 (45.07%), Query Frame = 3 
Query:  552 LWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVC-FQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLL-LCKTKTRNR-DTFSKP 1607
            +W+++   L F+    ++LTF+++      P  R + ++  C    S+ +I+RL  G  R  C F+  ++P+    L+    +N+    C+I FL  YFF  AS +WW +L LTWF   GL W    I+ +S  +H  AW  P + +++ L M  VD D +TGLC VGN N   L  F++APL  +   G  F+  G +++ +       RS L            T  +     + K+          G   ++ ++P         YE+   S+W +           SN  +   +I + +L       +GI  G WIW  +T ++W     RL+   K K + R D + KP
Sbjct:  207 IWMAVWASLCFISTAFTVLTFLIDSSRFCYP-ERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPV----LIQEGLKNTG---CAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNIDALTGFVVAPLFTYLVIGTLFIAAGLVALFKI------RSNLQ--------KDGTKTDKLERLMVKI----------GVFSVLYTVPATCVIACYFYEI---SNWNVFR----YTADDSNMAVEMLNIFMSLL-------VGITSGMWIWSAKTLHTWQKCTNRLVNSGKVKRKKRVDGWVKP 515
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Match: Fzd8 (frizzled class receptor 8 [Source:MGI Symbol;Acc:MGI:108460])

HSP 1 Score: 174.866 bits (442), Expect = 1.076e-45
Identity = 122/408 (29.90%), Postives = 193/408 (47.30%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQ-------------------------------DSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ + S  HP YN+V TG +ANCA PC +PF   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+++RLVAGH +  C                                         ++   +R++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN +  +L  F+LAPL ++   G  FL  GF+S+ R                 R++       +    L KL          G   ++ ++P  +    + YE   R  WE    C CL  +Q +     P   +++LKY     +GI  G W+W  +T  SW
Sbjct:  228 GCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID-MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRI----------------RSVIKQQGGPTKTHKLEKLMIR------LGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQ-ARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW 611
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Match: Fzd5 (frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571])

HSP 1 Score: 166.392 bits (420), Expect = 2.363e-43
Identity = 119/376 (31.65%), Postives = 181/376 (48.14%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            C CR P + I    HP YNKV TG + NCA PC  P    +       W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+GF++RLV GH    C +  S          + ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  Y+Q +H  AW  P + S+ AL +S+VDGDPV G+C VGN N   L  F+L PL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   L+ ++P  +     +YE  +R  WE A TC C     +      P   + +LKY     +GI  G WIW  +T  SW
Sbjct:  190 CTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLID-MERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSH---------IHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGP-DAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESW 530
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Match: Fzd5 (frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571])

HSP 1 Score: 166.392 bits (420), Expect = 2.363e-43
Identity = 119/376 (31.65%), Postives = 181/376 (48.14%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            C CR P + I    HP YNKV TG + NCA PC  P    +       W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+GF++RLV GH    C +  S          + ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  Y+Q +H  AW  P + S+ AL +S+VDGDPV G+C VGN N   L  F+L PL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   L+ ++P  +     +YE  +R  WE A TC C     +      P   + +LKY     +GI  G WIW  +T  SW
Sbjct:  190 CTCREPFVPILKESHPLYNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLID-MERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSH---------IHYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGP-DAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESW 530
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Match: Fzd2 (frizzled class receptor 2 [Source:MGI Symbol;Acc:MGI:1888513])

HSP 1 Score: 97.4413 bits (241), Expect = 1.240e-20
Identity = 113/394 (28.68%), Postives = 171/394 (43.40%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCR------SPFIENNRYNLIPLW-LSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLNQIQSNSYIP--TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDT 1595
            P Y      G  +CA PC       S F          LW L+ SV    +CC S+  T     V++   + P R + ++  C   +SV +I   V    R VC +  S+    +++     Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P + ++  L M  +DGD ++G+C VG  +   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L +L          G   ++ ++P  +      YE  +R HWE   ++  C  L       Y P  +P   +Y++KY     +GI  G WIW  +T +SW     RL    T +R+ +T
Sbjct:  213 PSYLSYKFLGERDCAAPCEPARPDGSMFFSQEETRFARLWILTWSV----LCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQE-RVVCNERFSEDGYRTVV-----QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLERLMVR------IGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL----TNSRHGET 568
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Match: Fzd10 (frizzled class receptor 10 [Source:MGI Symbol;Acc:MGI:2136761])

HSP 1 Score: 91.6633 bits (226), Expect = 1.022e-18
Identity = 100/361 (27.70%), Postives = 161/361 (44.60%), Query Frame = 3 
Query:  525 ENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELAST---CTCLNQIQSNSYIPT---PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNR 1589
            ++ R+ ++  WL+I   L F     ++LTF+++     + P R + ++  C    SVG+IIRL AG     C        +DS  L +  +    + C++ FL  Y+F  AS LWW +L LTWF   G  W    I+  S  +H  AW  P + ++L L M  V GD +TG+C VG+++   L  F+L PL  +   G  F+             S   +   I    +T   +T        L KL          G   L+ ++P         YE     +W++ +T   C   NQ ++   + T   P++ ++++K S    +GI  G W+W  +T  SW     R L  K K+R +
Sbjct:  223 DDKRFAVV--WLAIWSVLCFFSSAFTVLTFLIDPSRF-RYPERPIIFLSMCYCVYSVGYIIRLFAGAESIAC-------DRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLVPLACYLVIGTSFIL------------SGFVALFHIRRVMKTGGENT------DKLEKLMVR------IGVFSLLYTVPATCVIACYFYERLNMDYWKMLATQHKCKMNNQTKTPDCLMTTSIPAVEVFMVKVSMLLVVGITSGVWVWTSKTLQSWQHVCSRGL--KRKSRRK 547
[Close]
BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Match: sp|P58421|FZD5_XENLA (Frizzled-5 OS=Xenopus laevis OX=8355 GN=fzd5 PE=2 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 9.080e-47
Identity = 117/376 (31.12%), Postives = 185/376 (49.20%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            CKCR P + I    HP YN++ TG + NCA PC  P+   +    +  W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +S+G+++RL+ GH    C +             + ++ + P++C+I FL  YFF  AS +WW +L  TWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL V+  SG  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +     +YE  +R HWE    C+C    Q       P   +++LKY     +GI  G WIW  +T  SW
Sbjct:  177 CKCREPFVSITRESHPLYNRIKTGQVPNCAMPCFQPYFTQDEKMFVTFWIGLWSILCFISTFTTVATFLID-MERFRYPERPIIFLSACYLFVSIGYVVRLIVGHENVACNKDH-----------IHYETTGPALCTIVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVVYLFSGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFSVLYTVPATIVVACYIYEQHYREHWEKTHNCSCPGDKQRYR----PDYAVFMLKYLMCLVVGITSGVWIWSGKTLESW 512
[Close]
BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Match: sp|O93274|FZD8_XENLA (Frizzled-8 OS=Xenopus laevis OX=8355 GN=fzd8 PE=1 SV=1)

HSP 1 Score: 176.792 bits (447), Expect = 4.073e-46
Identity = 122/384 (31.77%), Postives = 191/384 (49.74%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIP-TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVR 1556
             C+CR+PM+++ +  HP YN+V TG + NCA PC +PF           W+ +   L F    +++ TF+++ +E  + P R + ++  C + +S G++IRL+AGH +  C + +       L  ++ ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P I S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE+A  C   N  Q     P  P   +++LKY     +GI  G WIW  +T  SW     R
Sbjct:  190 GCQCRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTFATVSTFLID-MERFKYPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGEL-----DLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNC---NSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTR 540
[Close]
BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Match: sp|Q9H461|FZD8_HUMAN (Frizzled-8 OS=Homo sapiens OX=9606 GN=FZD8 PE=1 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 5.084e-45
Identity = 122/407 (29.98%), Postives = 193/407 (47.42%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVC------------------------------FQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ + S  HP YN+V TG +ANCA PC +PF   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+++RLVAGH +  C                                        ++   +R++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN +  +L  F+LAPL ++   G  FL  GF+S+ R                 R++       +    L KL          G   ++ ++P  +    + YE   R  WE    C CL  +Q +     P   +++LKY     +GI  G W+W  +T  SW
Sbjct:  231 GCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID-MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGAGAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRI----------------RSVIKQQDGPTKTHKLEKLMIR------LGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQ-ARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW 613
[Close]
BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Match: sp|Q61091|FZD8_MOUSE (Frizzled-8 OS=Mus musculus OX=10090 GN=Fzd8 PE=1 SV=2)

HSP 1 Score: 174.866 bits (442), Expect = 7.528e-45
Identity = 122/408 (29.90%), Postives = 193/408 (47.30%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQ-------------------------------DSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ + S  HP YN+V TG +ANCA PC +PF   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+++RLVAGH +  C                                         ++   +R++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN +  +L  F+LAPL ++   G  FL  GF+S+ R                 R++       +    L KL          G   ++ ++P  +    + YE   R  WE    C CL  +Q +     P   +++LKY     +GI  G W+W  +T  SW
Sbjct:  228 GCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID-MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRI----------------RSVIKQQGGPTKTHKLEKLMIR------LGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQ-ARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW 611
[Close]
BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Match: sp|Q498S8|FZD8_RAT (Frizzled-8 OS=Rattus norvegicus OX=10116 GN=Fzd8 PE=2 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 1.132e-43
Identity = 122/408 (29.90%), Postives = 193/408 (47.30%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQ-------------------------------DSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+CR+PM+ + S  HP YN+V TG +ANCA PC +PF   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+++RLVAGH +  C                                         ++   +R++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN +  +L  F+LAPL ++   G  FL  GF+S+ R                 R++       +    L KL          G   ++ ++P  +    + YE   R  WE    C CL  +Q +     P   +++LKY     +GI  G W+W  +T  SW
Sbjct:  227 GCQCRAPMVSVSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFLID-MERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAATAGAGAAGAGASSPGARGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRI----------------RSVIKQQGGPTKTHKLEKLMIR------LGLFTVLYTVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQ-ARRPDYAVFMLKYFMCLVVGITSGVWVWSGKTLESW 610
[Close]
BLAST of Fzd-5/8-2 vs. TrEMBL
Match: T1E1C5 (Fzd-5/8-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1021.15 bits (2639), Expect = 0.000e+0
Identity = 537/541 (99.26%), Postives = 538/541 (99.45%), Query Frame = 3 
Query:  336 DFDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 1958
            DFDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGL NCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPL LTTGSIVYEMRWRSHWELASTCTCLNQI+SNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSC TSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS
Sbjct:   11 DFDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLVNCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLCLTTGSIVYEMRWRSHWELASTCTCLNQIESNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCQTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 551
[Close]
BLAST of Fzd-5/8-2 vs. TrEMBL
Match: A0A1S6KMG8 (G_PROTEIN_RECEP_F2_4 domain-containing protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 953.74 bits (2464), Expect = 0.000e+0
Identity = 506/510 (99.22%), Postives = 507/510 (99.41%), Query Frame = 3 
Query:  429 MIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 1958
            MIKIDSVHHPYYNKVHTGGL NCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPL LTTGSIVYEMRWRSHWELASTCTCLNQI+SNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSC TSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS
Sbjct:    1 MIKIDSVHHPYYNKVHTGGLVNCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLCLTTGSIVYEMRWRSHWELASTCTCLNQIESNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCQTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 510
[Close]
BLAST of Fzd-5/8-2 vs. TrEMBL
Match: Q589S5 (Frizzled receptor OS=Dugesia japonica OX=6161 GN=DjfzA PE=2 SV=1)

HSP 1 Score: 824.313 bits (2128), Expect = 0.000e+0
Identity = 436/541 (80.59%), Postives = 482/541 (89.09%), Query Frame = 3 
Query:  336 DFDFKSPPTIENHFPINNHS-NFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFH 1955
            + + K    +E   P NN S N  CNCKCRSPMIKIDSVHH YYNKV+TGG+ NCAWPCRSPFIENNRY LI LWLSISVGLIF+CCISSLLTF LNR+ELIQPPHRFVAYICCCQIGMS+GFIIRLVAGHY+TVCFQPD KPI +SLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFF+DGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSG FFL CGFLS+ +CD+SS++RSKLS+PVSPRTISTDTSVESAASSLPK+TTS+ITK FYGFLGLICSIPL LTTGSIVYEMRWRSHWE+ +TC+CLN+++SNSY+ TPSILLY+LKYSGFFA+GIICGPWIWPMQT+N+WL  I+ L LCK+   NRDTF KPKP HICQAQ L NT+YTIT    T+C RQ+CLL+P   NDSL+MSSL P+ KCQHRFP SRLHEI ++H+IAPDAESYASYQSLSNY+ N  K+P   YEFYKK++ MS NWP+FH
Sbjct:  187 ELETKPLQRVEKIIPTNNRSSNVRCNCKCRSPMIKIDSVHHAYYNKVYTGGIINCAWPCRSPFIENNRYYLISLWLSISVGLIFICCISSLLTFFLNRLELIQPPHRFVAYICCCQIGMSIGFIIRLVAGHYKTVCFQPDYKPIHESLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFSDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGLFFLACGFLSVTKCDQSSSHRSKLSVPVSPRTISTDTSVESAASSLPKITTSSITKCFYGFLGLICSIPLCLTTGSIVYEMRWRSHWEVLTTCSCLNEMESNSYLSTPSILLYILKYSGFFAIGIICGPWIWPMQTFNTWLEPIIHLFLCKSNQGNRDTFCKPKPTHICQAQPLCNTSYTIT----TTCHRQDCLLEPSNTNDSLLMSSLKPLPKCQHRFPTSRLHEISVDHTIAPDAESYASYQSLSNYNPNHLKHPHEFYEFYKKNN-MSKNWPVFH 722
[Close]
BLAST of Fzd-5/8-2 vs. TrEMBL
Match: T1DBM9 (Fzd-5/8-2 (Fragment) OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 508.449 bits (1308), Expect = 2.022e-171
Identity = 290/463 (62.63%), Postives = 358/463 (77.32%), Query Frame = 3 
Query:  570 VGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDT-SVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFH 1955
            VGLI + C++S+LTFVLNR EL + PHRF+ Y+CCCQIGMS+G IIRLVAGHY+TVC+QPD+KPI+ SLLL+LRFQNSAPSVCSISFLFTYFFF ASVLWWW+LC+TWF  +GLGW+++MIDKYSQLYHFI+WF PGI SMLALTMSAVDGDPVTGLCLVGNINR+HLITFLLAPLCV TCSGFFFL CGF ++ + D+S+ NR+KLSI  S R +S +T +  + +SSL KLT S ++++FYG LG ICS+PL +T GSI+YEMRWR+ WEL +TC CLN+I  NSY+PTP+I LY+LKY GFFA+GIICGPWIWP   + SWLG I   L C +  + +      KP H  Q QQ YNT YTIT    TS  R + LL+P   NDSL+MSS+ P  KCQHRFP +   ++ ++ +++PD +SYASYQ+LS++      N Q + E YK     + NWP FH
Sbjct:    1 VGLILLSCLTSILTFVLNRSELKKAPHRFIVYMCCCQIGMSIGVIIRLVAGHYKTVCYQPDNKPIEQSLLLLLRFQNSAPSVCSISFLFTYFFFLASVLWWWVLCVTWFLREGLGWTTTMIDKYSQLYHFISWFIPGILSMLALTMSAVDGDPVTGLCLVGNINREHLITFLLAPLCVCTCSGFFFLACGFFTLNQTDQSTVNRTKLSITASTRPLSRNTSAESAESSSLAKLTKSKVSRYFYGILGFICSVPLCITMGSIIYEMRWRNQWELITTCPCLNKISPNSYMPTPTISLYLLKYFGFFAIGIICGPWIWPNYAFESWLGPIFYTLCCYSNPQEKCL----KPKH--QPQQFYNTTYTIT----TSSHRHDRLLEPSNTNDSLVMSSIRPQPKCQHRFPPNIPVDVTMDGNLSPDTDSYASYQTLSHFSQTPIPNNQGIIECYKGIS-HTNNWPQFH 452
[Close]
BLAST of Fzd-5/8-2 vs. TrEMBL
Match: T1DF42 (Fzd-5/8-3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 203.371 bits (516), Expect = 5.685e-52
Identity = 143/405 (35.31%), Postives = 212/405 (52.35%), Query Frame = 3 
Query:  390 HSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNR-YNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLL--CKTKTRNRDT 1595
            +S  +C C CR P+I I  ++  ++N+V T G+ NCA  C+SPF  +      I  WL +   +  +   S + TF ++     + P R + ++  C   +S+GF+IR+V GH    C    +K    S L +LR+  S P+ C+I FL  Y+F  A+ LWW LL +TWF   GL W S  I KYSQ+YHF+AWF PGI S++ALTMSAVDGDPV+G+C VGN +  +LI F+L+PL V+   G   L  GF S+ R       RS + +    +T             L KL          G   ++ + P  +    I+YE++ R+ W    +C C +  +    +P PS  +++ KY  F  +G+  G WIW  +T  SW     RL +  C  + RN+ T
Sbjct:  206 NSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRY-RYPERPIIFMSICYFMVSLGFLIRIVMGHEDLACDLIKAK--DGSSLSLLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRI------RSIIKLQTGGKT-----------EKLEKLMIR------IGVFSVLYTAPAAVIVACIIYELQNRAEWYQNLSCDCFDSNRHQLNLPRPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSWKMVCYRLGINSCHVEERNKHT 584
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BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Match: ENSAMXT00000026985.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:27065879:27070162:-1 gene:ENSAMXG00000026259.2 transcript:ENSAMXT00000026985.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 188.348 bits (477), Expect = 3.624e-51
Identity = 131/421 (31.12%), Postives = 206/421 (48.93%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTS 1670
             C+CR P++ I    HP YN+V TG L NCA PC  P+   +       W+ +   L FV  ++++ TF+++ +E  + P R + ++  C + +S+G+I+RL+AGH +  C        Q  +L    +  + P++C++ FL  YFF  AS +WW +L  TWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN + + L  F+LAPL V+  SG  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +    +VYE  +R  WE A  C+C ++ Q       P   +++LKY     +GI  G WIW  +T  SW   + R   C+ +          KPP    A  +Y+   T  T+
Sbjct:  191 ECRCREPLVPIKKESHPLYNRVQTGSLPNCALPCHQPYFSQDERAFTTFWIGLWSVLCFVSTLTTVATFLID-MERFKYPERPIIFLAACYLFVSLGYIVRLLAGHEKVAC---GGSGDQRHIL----YDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLESLRGFVLAPLVVYLFSGSLFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGLFTVLYTVPATIVVACLVYEQHYRPEWEQALGCSCASERQQQGL--GPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRRFVARCFPCRAR----------KPP--ASASSMYSEASTALTA 565
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BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 182.956 bits (463), Expect = 1.791e-49
Identity = 119/383 (31.07%), Postives = 198/383 (51.70%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVR 1556
             C+CR+PM++++S  HP YN+V TG + NCA PC +P+   +       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +S+G+I+RL+AGH +  C        ++  +  + ++ + P++C++ FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGDPV G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE +  C+CL + +    +  P   +++LKY    ++GI  G WIW  +T +SW     R
Sbjct:  164 GCQCRAPMVRVNSERHPLYNRVKTGQMPNCAMPCHNPYFTQDERTFTAFWIGLWSVLCFVSTFATVATFLID-MERFKYPERPIIFLSACYMFVSIGYIVRLIAGHEKVAC-------SREYDVEHVHYETTGPALCTVVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYSQYFHLAAWLIPSMKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTVLYTVPATIIVACYFYEQHNRQSWETSHNCSCLMEHE----LRRPDYAVFMLKYFMCLSVGITSGVWIWSGKTLDSWRALCTR 510
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BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Match: fzd4 (frizzled class receptor 4 [Source:NCBI gene;Acc:103039803])

HSP 1 Score: 89.7373 bits (221), Expect = 2.237e-18
Identity = 114/450 (25.33%), Postives = 190/450 (42.22%), Query Frame = 3 
Query:  336 DFDFKSPPTIE-NHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNK-----------VHTGGLANCAWPCRSP------FIENNRYN-----LIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTR---NRDTFSKP 1607
            +F F  P  +  + FP  N  N  C      P    D + HP  NK           +  GG    AW  RS         E+  Y         +W+++   L F+    ++LTF+L+       P R + ++  C    SV F++RL AG  R  C       + ++ + +L  +    + C++ FL  YFF  AS +WW +L LTWF   GL W    I+ +S  +H  AW  P + +++ L M  VD D +TGLC VGN N   L  F++APL  +   G  F+  G +++ +       RS L            T  +     + K+          G   ++ ++P         Y++   S+W         +Q   +SY+    + +++        +GI CG W+W  +T ++W    +RLL  +  +R   + + ++KP
Sbjct:  121 EFGFVWPELLNCSLFPPTNDQNHMC---MEGP--AEDDLFHP--NKPVAPHEEECVTMGGGGPEQYAWAKRSGSCVLQCGYESGLYRRQAKMFTDVWMAVWAVLCFISTSFTVLTFLLDSARF-SYPERPIMFLSMCYNVYSVAFLVRLTAGRERISC------DLDEAAVPVLAQEGLKNTGCAVVFLLAYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADDLTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKI------RSNLQ--------KDGTKTDKLERLMVKI----------GVFSVLYTVPATCVIACYFYQI---SNW------ADFHQTARDSYMAAEMLRIFM-----SLLVGITCGMWVWSAKTLHTWQRCSLRLLHSRRSSRAHQSGEGWAKP 518
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229])

HSP 1 Score: 90.1225 bits (222), Expect = 2.310e-18
Identity = 103/388 (26.55%), Postives = 164/388 (42.27%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSP------FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELA---STCTCLN-QIQSNSYIP-TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKT 1580
            P Y      G  +C  PC         +          LW+ I      +CC+S+L T +   V++   + P R + ++  C   ++V ++   +    + VC     +    ++      Q +    C+I F+  YFF  AS +WW +L LTWF + G+ W    I+  SQ +H  AW  P + ++  L +  VDGD +TG+C VG  N   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R  WE      TC        S+++ P +P   ++++KY     +GI  G WIW  +T  SW     RL   + +T
Sbjct:  205 PSYLNYKFLGAKDCGAPCEHSQPHGLMYFREEEMKFGRLWVGIWA---ILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYVTGFLLED-KVVCIDKFREDAYRTVA-----QGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILALGQVDGDLLTGVCFVGIYNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHMQTCKRFAVPCPSSNFAPMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRSFYKRLGNAQGET 559
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BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Match: fzd9a (frizzled class receptor 9a [Source:ZFIN;Acc:ZDB-GENE-060531-77])

HSP 1 Score: 87.4261 bits (215), Expect = 1.664e-17
Identity = 94/350 (26.86%), Postives = 155/350 (44.29%), Query Frame = 3 
Query:  552 LWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWEL-ASTCTCLNQIQSNSYIPT-----PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTR 1583
            +W+ +   L FV    ++LTF+L+  +  Q P R + ++  C    SV FIIR VAG     C + + +       L +  +    + C+I FL  Y+F  AS +WW +L LTWF   G  W    I+ +S  +H +AW  P + +++ LTM  V GD +TGLC VG+++   L  F++ PL  +   G  F+             +   +   I    +T  T+T        L KL          G   ++ ++P         YE     +W+  AS   C++     +   T     P++ +++LK      +GI  G W+W  +T  +W G   R L  +T  +
Sbjct:  243 IWMVVWSTLCFVSTAFTVLTFLLDP-QRFQYPERPIIFLSMCYNVYSVAFIIRSVAGAENIACDRENGQ-------LYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMVAWGIPAMKTIVILTMRKVAGDELTGLCYVGSMDTNALTGFIIIPLSCYLIIGTSFIL------------TGFVALFHIRKIMKTGGTNT------EKLEKLMVK------IGVFSILYTVPATCVIICYFYERLNMDYWKFRASESKCVSFPGRRTEDCTLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCARKLAMRTTRK 560
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 161.384 bits (407), Expect = 8.282e-44
Identity = 125/402 (31.09%), Postives = 190/402 (47.26%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPT--PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPK 1610
            C CR+P+++I +  H  Y++V TG + NCA PC SPF+   +      W+ +   L F    +++ TF+++ +E  + P R + ++  C +  S+G+I+R+VAGH    C    S      L     + +S P++C+  FL TYFF  A  +WW +L LTWF   GL W S  I  YSQ YH  AW  P I ++ AL M+AVDGDPV G+C VGN +  +L  F+LAPL  +   G  FL  G +++ R           +I  +P    T+         L +L          G   ++ ++P  +     +YE + R  WE    C        +   P   P   +++LKY      GI  G WIW  +T  SW     R    +   R+R      +
Sbjct:    5 CGCRAPLVRISNPRHVLYDRVRTGQVRNCATPCHSPFLGREQRTFASFWIGLWSSLCFAATFATVSTFLID-MERFKYPERPIIFLSLCCMLASLGYIVRMVAGHEAVAC----SADWHHVL-----YASSGPALCTAVFLLTYFFGMAGCVWWVILSLTWFMAAGLKWGSEAIAGYSQYYHLAAWLLPSIKAIAALAMNAVDGDPVAGICSVGNQSLDNLRGFVLAPLVAYLLVGTAFLLAGLVALFRIRN--------AISANPGGAKTE--------KLERLMVR------IGVFAVLYTVPAAVAVVCHLYEQQHRDSWERTLVCGACGPGPGHLPEPGARPDFAVFMLKYFVCLVGGITSGAWIWSGKTAGSWKRFYKRCRAWRAGKRHRSPIGAGR 374
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011009.1 (pep scaffold:Pmarinus_7.0:GL485859:2701:4509:1 gene:ENSPMAG00000009982.1 transcript:ENSPMAT00000011009.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 165.236 bits (417), Expect = 1.117e-43
Identity = 121/383 (31.59%), Postives = 185/383 (48.30%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFY--GFLGLICSIPLFLTTGSIVYEMRWRSHWELASTC-TCLNQIQSNSYIPT---PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C CR+PM+ I S  HP YN+V TG + NCA PC  P+   +       W+ +   L FV   ++++TF+++ +E  + P R + ++  C   +S+G+I+RLV GH   +C Q             + ++ + P++C++ FL TYFF  AS +WW +L LTWF   G+ WSS  I  YSQ YH  AW  P + S+  L  S+VD DP+ G+C VG  + ++L  F+L PL V+ C G  FL  GF S++R                         + +A        T  + K     G   ++ ++P         YE R R  W  A  C +C    +  S       P   +++LKY     +GI  G WIW  +T ++W
Sbjct:  174 GCACRAPMVAIGSDRHPLYNRVRTGSVLNCAMPCHDPYFTQDERTFASFWIGLWSILCFVSTFTTVVTFLID-MERFKYPERPIIFLSACYAFVSMGYIVRLVVGHDGVICNQEHRH---------VHYETTGPALCTVVFLLTYFFGMASSIWWVILSLTWFMAAGMKWSSEAIAGYSQYYHLAAWLLPSVQSVAVLATSSVDADPLAGICSVGAQSLENLRGFVLVPLTVYLCVGAVFLLAGFTSLVR-------------------------IRNAIKQQGGTKTDKLEKLMVRIGIFSMLYTVPAIAVVACYFYEERSRDGWARALICPSCQGDEEPGSQQQQQQRPDYGIFMLKYFMCLVVGITSGVWIWSGKTVDTW 521
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223])

HSP 1 Score: 94.3597 bits (233), Expect = 2.333e-20
Identity = 111/379 (29.29%), Postives = 168/379 (44.33%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSPFIENN--RYNLIPLWLS-ISVGL-IFVCCISSLLTFV--LNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLNQIQSNSYIPT--PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            P Y      G   C  PC  P   N    ++   LW + + VG+   +CC S+L T +  L  +E  + P R + ++  C   +S+ +I+       + VC    +K  +DS   ++  Q +    C+I F+  YFF  AS +WW +L LTWF + G+ W    I+  SQ +H  AW  P I ++  L M  VDGD +TG+C VG  +   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R+ WE   +A TC          + P   P   ++++KY     +GI  G WIW  +T  SW     RL
Sbjct:  239 PSYLNYQFLGKKECGSPCE-PSKSNGLMYFDADELWFARMWVGVWSILCCASTLFTVLTYLVDMERFRYPERPIIFLSGCYAVVSIAYIVGFFFEE-KIVC----NKFFEDSYSTVV--QGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGLNSIDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGIFSVLYTVPATIVIACYFYEQAFRAQWEKSWVAHTCKSFAVQCPQGHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLQSWRNFYSRL 585
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224])

HSP 1 Score: 87.4261 bits (215), Expect = 2.948e-18
Identity = 100/362 (27.62%), Postives = 159/362 (43.92%), Query Frame = 3 
Query:  492 NCAWPC--RSP----FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLNQIQSNSYIPT--PSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            NCA PC  + P    +          LW+ I   L   CC S+L T     V++   + P R + ++  C   ++V ++   +    + VC +  S+ I  ++      Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P + ++  L M  VDGD ++G+C VG  +   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R  WE   ++ +C         ++ P   P   ++++KY     +GI  G WIW  +T +SW
Sbjct:  196 NCAAPCEPKKPNGLMYFSEEELRFSRLWVGIWSVL---CCASTLFTVTTYLVDMQRFRYPERPIIFLSGCYFMVAVAYVAGFLLDD-KVVCNEQFSEDIYRTVT-----QGTKKEGCTILFMLIYFFSMASSIWWVVLALTWFLAAGMKWGHEAIEANSQYFHLAAWAIPAVKTITILAMGLVDGDMLSGVCFVGISSVAALRGFVLAPLFVYLFLGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGIFSVLYTVPATIVIACYFYEQAFREQWEKTWVSQSCKGFAIPCPLNHYPNMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLHSW 524
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Match: fzd3b (frizzled class receptor 3b [Source:ZFIN;Acc:ZDB-GENE-070122-1])

HSP 1 Score: 63.1586 bits (152), Expect = 1.153e-10
Identity = 87/360 (24.17%), Postives = 149/360 (41.39%), Query Frame = 3 
Query:  483 GLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFY--GFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLN---QIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            G+ +C+ PC + +  +    L    + +   +  V    + LTF+L+R +  + P R + +   C + +S+ F++  +       C  P   P     +      N A   C+  F+  YF   A  LWW +L +TWF   GL W    I+K +  +H +AW  P   ++  L ++ V+GD ++G+C  G  +   L  F+LAPL     +G   L  G +        S NR +L +    R                    + + KF    G   ++  +P       +VYE   R+ WE   L   CT        Q+N     P+++L+++KY     +GI    W+   +T   W
Sbjct:   26 GVPDCSPPCPNMYFSSGELELTRYLVGVMSVVCLVATTFTFLTFLLDR-KRFRYPERPIIFYATCYVAVSLSFLVGFLLDDSAAACNAPGLAPGAAGTVTQGSRNNKA---CTAVFMLLYFSAMAGALWWVVLTITWFLAAGLKWGREAIEKRAAAFHALAWGPPAALTVALLALNKVEGDNLSGVCYAGLYDVTTLRYFVLAPLGACAAAGLSLLLAGIV--------SLNRVRLEMRHDGR------------------NQTKLVKFMVRIGVFSVLYLVPQLALVACLVYEQASRAAWEATWLRDRCTEYRIPCPYQANQPKQRPALVLFLVKYFTTLVVGIPPAFWVGSRKTCLGW 355
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Nematostella
Match: EDO42932 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S003])

HSP 1 Score: 138.658 bits (348), Expect = 1.279e-34
Identity = 121/383 (31.59%), Postives = 183/383 (47.78%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            C CR P + I   +      +  GG+  CA  C   +  +++ +    W+ +   L F+  + + LTF+++ +   + P R + ++  C + +SVG+IIRL+AGH +  C         DS  LM R+  S P+ C+I FL  YFF  AS +WW +L  TWF + G+ WSS  I  YSQ +H +AW  P I ++  L MS +DGDPV+G+C VGN N Q L+ F++ PL V+   G  FL  GF S++R       R  L    S +T             L KL          G   ++ ++P  +      YE+  R  WE    C+     +       P   ++++KY     +GI  G WIW  +T  SW     RL
Sbjct:  175 CSCRPPFVSIAGKNIKPTRAISVGGVPQCAMACNRTYFTHDQDSFASFWIGLWAILCFISTLVTTLTFLVD-MHRFKYPERPIIFLSGCYLMVSVGYIIRLIAGHKQIAC---------DSNGLM-RYDTSGPASCTIVFLLVYFFGMASSVWWVILAFTWFLSAGMKWSSEAITNYSQYFHAVAWLVPAIQAIAVLAMSTIDGDPVSGICYVGNHNLQSLVVFVIVPLVVYLVFGTSFLMAGFYSLVRI------RKLLRQHGSTKT-----------DKLEKLMIR------IGVFSVLYTVPATIVVACYYYELVNRETWERTINCSGCGVTRVK-----PDHSVFIIKYFMALVVGITSGFWIWSGKTIESWRNFCARL 518
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Nematostella
Match: EDO38567 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCF4])

HSP 1 Score: 119.013 bits (297), Expect = 6.105e-28
Identity = 110/402 (27.36%), Postives = 186/402 (46.27%), Query Frame = 3 
Query:  351 SPPTIENHFPINNHSNFWCNCKCRSPMIK-IDSVHHPYYNKVHTGGLANCAWPCRSPFI-ENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELAS---TCTCL-NQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            + P I+   P+N  S+ W N +   P  K I++     Y   +      C   C+S  +  +N      +W+S+   L F+    ++LTFV++     + P R + ++  C    S+G+I+R+ AG    +C + +S  I+  + +      +  + CS+ FL  Y+F  AS +WW +L   WF   G  W    I++ +  +H +AW  P I +++AL M  VD D +TGLC VGN++ ++L  ++L PLC++   G FFL  GF+S+ R      N+                  E+    L KL          G   ++ +IP+        YE      W++ +   T  C  +Q    +Y   PSI ++++KY     +GI    WIW  +T+ SW
Sbjct:  153 AAPNIKQTAPLN-ESDIWSNFESLGPEFKKINNTGPLRYKYTYVEKYDQCVPQCKSDLMFSSNNKRFANVWISVWSVLCFISTAVTVLTFVIDTSRF-KYPERPIIFLSLCYNLYSLGYIVRVTAGRNEVICDETESFVIRAGMNI------ADHACCSVVFLLLYYFGMASAVWWVVLTFAWFLAAGRKWGQEAIERKATYFHAVAWTVPAIQTIMALIMRKVDADELTGLCYVGNMDYENLANYVLTPLCLYLLVGTFFLLAGFVSLFRIRTVLKNK------------------ETNTDKLEKLIVR------IGVFSVLYTIPVSAVIACSFYEYNNMDVWKVRAPFNTYICRGDQACLENY--GPSIEVFIVKYFMLLIIGITSNMWIWSTKTFKSW 520
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Nematostella
Match: EDO35751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKM6])

HSP 1 Score: 110.153 bits (274), Expect = 2.385e-25
Identity = 106/377 (28.12%), Postives = 168/377 (44.56%), Query Frame = 3 
Query:  483 GLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEM--------RWRSHWELASTCTCLN-QIQSNSYIP-------TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLL 1565
            G   CA  CR+ F       +  +W  I   L  V  + ++LTF+++ +   + P R + ++  C   +S+ FI   VAG  +  C +P  K    +L+     Q +    C++ F+  YFF  AS +WW +L +TWF   GL W    I+  SQ +H  AW  P + ++  L M+ VDGD ++G+C VG  +   L  ++LAPL V+   G  FL  GF+S+ R       RS L    S R              + KL          G   ++ ++P  +  G + YE          W   W+    CT +  +++     P        P  +++++KY  F  +GI  G WIW  +T NSW     R +L
Sbjct:  187 GEKRCAATCRNVFFTKREREIARMWTGIWAILCAVSTLFTILTFLID-MRRFRYPERPIIFLSGCYFMVSIAFITGYVAGD-KIACNEPIKKGFPKTLV-----QGTKHEGCTVIFMMLYFFSMASSIWWVILTVTWFLAAGLKWGQEAIEANSQFFHLAAWAIPAVKTIAILLMTKVDGDELSGVCYVGLSDVSALRGYVLAPLFVYFIIGATFLLAGFISLFRV------RSVLKDDYSKR------------EKIEKLMIR------IGVFSILYTVPALVVIGCLYYEQSNRELWDNSWIEGWKRQKKCTEVETKLKGEVSCPPYPVPLQKPDFMVFMVKYLMFLIVGITSGFWIWSSKTLNSWRRFYRRFIL 532
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Nematostella
Match: EDO30865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZJ6])

HSP 1 Score: 85.5001 bits (210), Expect = 1.934e-17
Identity = 94/345 (27.25%), Postives = 142/345 (41.16%), Query Frame = 3 
Query:  645 PHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKP-------IQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYT 1658
            P R + ++  C    S+ +IIRL AG     C   D+ P       IQD L      +N+    C+I FL  YFF  A+ +WW +L LTWF   G+ W    I  Y++L+H IAW  P I ++  L    VDGD +TGLC VGN +   L  F+L P   +   G  FL  GF+++ R                       T+V+    +        I +   G   ++ ++P         YE   + +W            Q +  +  P+  +++LK       G+I G WIW  +T N+W     ++             S  +PP   +     NTN T
Sbjct:  221 PERSIIWLALCYNFYSLSYIIRLGAGRQAISC---DTDPTTHVKFHIQDGL------RNTG---CAIVFLIQYFFCMAATIWWVVLALTWFLAAGMKWGCEAIGSYAKLFHIIAWILPCIKTIFILITRKVDGDELTGLCFVGNQDLIALAAFVLGPQFTYLIIGTLFLIAGFVALFR---------------------IRTTVQRGGQAKTDKLERLIVRI--GIFSVLSTVPATAVIACYFYEYANKEYWYYG---------QRDGAVAEPNFSIFMLKVFMSLFTGVITGMWIWSHKTMNTWRAFYYKV-------------SGKRPPRKLERNGNGNTNET 508
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BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Match: ENSORLT00000013002.2 (pep primary_assembly:ASM223467v1:21:5638676:5644296:-1 gene:ENSORLG00000010376.2 transcript:ENSORLT00000013002.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 183.341 bits (464), Expect = 1.839e-49
Identity = 129/407 (31.70%), Postives = 203/407 (49.88%), Query Frame = 3 
Query:  348 KSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLC 1568
            KS P +    P  +  +    C+CR P+I I    H  + +V TG L NCA PC  P+   +       W+ +   L F+  ++++ TF+++ +E  + P R + ++  C + +S+G+IIRLVAGH R  C    +  +       + +  + P++C++ FL  YFF  AS +WW +L  TWF   G+ W S  I  YSQ +H  AW  P + S+L L +S+VDGDPV G+C VGN + ++L  F+LAPL V+  +G  FL  GF+S+ R                 R+I     ++   +   KL    I     G   ++ ++P  +    +VYE  +R  WE A  C+C   ++    I  P   +++LKY     +GI  G WIW  +T  SW   + R   C
Sbjct:  153 KSTPKVRTRPPSPSQCDR--ECRCRDPLIPIKRESHALFGRVQTGPLPNCALPCHLPYFSADERAFTSFWVGLWSVLCFISTLTTVATFLID-MERFKYPERPIIFLAACYLFVSLGYIIRLVAGHERVACGAGGTSQLH------ILYDATGPALCTLVFLLVYFFGMASSIWWVVLSFTWFLAAGMKWGSEAIAGYSQYFHLAAWLIPSVKSILVLALSSVDGDPVAGICYVGNQSLENLRGFVLAPLVVYLFTGTLFLLAGFVSLFRI----------------RSI-----IKQGGTKTDKLERLMIR---IGLFTVLYTVPATIVVACLVYEQHYRPSWERALACSC--PLERQRSIRGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRSFVARCCPC 524
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3])

HSP 1 Score: 169.088 bits (427), Expect = 1.803e-44
Identity = 117/378 (30.95%), Postives = 191/378 (50.53%), Query Frame = 3 
Query:  408 NCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTC-TCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
             C+C  PM+ + +  HP YN+V TG + NCA PC +P+  ++       W+ +   L FV   +++ TF+++ +E  + P R + ++  C + +SVG+I+RL+AGH +  C +       D  +  + ++ + P++C+I FL  YFF  AS +WW +L LTWF   G+ W +  I  Y+Q +H  AW  P + S+  L +S+VDGD V G+C VGN N  +L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE+   C +CL  ++       P   +++LKY     +GI  G WIW  +T +SW
Sbjct:  183 GCRCLEPMVAVTTERHPLYNRVKTGQVTNCAMPCHNPYFTHDERAFTAFWIGLWSVLCFVSTFATVATFLID-MERFKYPERPIIFLSACYMFVSVGYIVRLIAGHEKVACNR-------DFDVEHIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYAQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLEKLMIR---IGIFTVLYTVPATVIVACYFYEQHNRQDWEMTHNCSSCL--MERERARSGPDYAVFMLKYFMCLLVGITSGVWIWSGKTLDSW 526
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Match: ENSORLT00000002667.2 (pep primary_assembly:ASM223467v1:17:316235:318512:1 gene:ENSORLG00000002147.2 transcript:ENSORLT00000002667.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 168.703 bits (426), Expect = 2.931e-44
Identity = 117/376 (31.12%), Postives = 185/376 (49.20%), Query Frame = 3 
Query:  411 CKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSW 1538
            C CR+PM+ + S  HP +N+V TG + NCA PC +P+           W+ +   L F+   +++ TF+++ +E  + P R + ++  C + +SVG+I+RLVAGH    C   +           + ++ + P++C+I FL  YFF  AS +WW +L LTWF   G+ W +  I  YSQ +H  AW  P + S+  L +S+VDGD V G+C VGN N   L  F+LAPL ++   G  FL  GF+S+ R                       + ++   +   KL    I     G   ++ ++P  +      YE   R  WE+   CTC  +         P+  +++LKY     +GI  G WIW  +T ++W
Sbjct:  188 CSCRAPMVPVSSEGHPLHNRVRTGQIVNCAVPCYNPYFTQEERTFTSFWIGLWSILCFISTFTTVATFLID-MERFKYPERPIIFLSACYMFVSVGYIVRLVAGHEEVACNMWNGAG-------YIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIGSYSQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGVCYVGNQNLDSLRGFVLAPLVIYLVIGTMFLLAGFVSLFR---------------------IRSVIKQGGTKTDKLERLIIR---IGVFTVLYTVPATVIVACYFYEQHNRQAWEITHNCTCATEPSKQR----PNYAVFMLKYFMCLLVGITSGAWIWSGKTLDTW 527
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224])

HSP 1 Score: 93.9745 bits (232), Expect = 1.183e-19
Identity = 109/397 (27.46%), Postives = 167/397 (42.07%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSP------FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVC---FQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWE---LASTCTCLN---QIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDT 1595
            P Y   H     +C  PC SP      F  +   +   +W+ I   L   CC S+  T     +++   + P R + ++  C   +S+ FI     G  +  C   F PD              Q +    C+I F+  YFF  AS +WW +L LTWF   G+ W    I+  SQ +H  AW  P + ++  L M  ++GD ++G+C V   N   L  F+LAPL ++   G  FL  GF+S+ R                 RTI      ++    L +L          G   ++ ++P  +      YE  +R HWE   ++  C  L      QS  ++ TP   +Y++KY     +GI  G WIW  +T +SW     RL    T  +N +T
Sbjct:  190 PPYLNYHFLEEKDCGAPCESPRNGGNMFFSDKEIHFARMWVLIWSVL---CCTSTFFTVTTYLIDMQRFRYPERPIIFLSGCYTMVSIAFIAGYFLGD-KVACNDSFNPDGYKTV--------VQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTISILAMGQIEGDVLSGVCFVSLSNLDPLRGFVLAPLFIYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEQLMVR------IGVFSVLYTVPATIVIACFFYEQAFRPHWERSWVSRNCRSLAIPCPAQSRPHM-TPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL----TSGKNGET 545
[Close]
BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229])

HSP 1 Score: 92.4337 bits (228), Expect = 3.800e-19
Identity = 106/390 (27.18%), Postives = 166/390 (42.56%), Query Frame = 3 
Query:  456 PYYNKVHTGGLANCAWPCRSP------FIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVEL--IQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRF---------QNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELA---STCTCLN-QIQSNSYIP-TPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL 1559
            P Y      G+ +C  PC         +   +      LW+ I      +CC+S+L T +   V++   + P R + ++  C   ++V +     AG +           ++D ++ + +F         Q +    C+I F+  YFF  AS +WW +L LTWF + G+ W    I+  SQ +H  AW  P I ++  L M  VDGD +TG+C VG  N   L  F+LAPL V+   G  FL  GF+S+ R                 RTI      ++    L KL          G   ++ ++P  +      YE  +R HWE      TC         +++ P TP   ++++KY     +GI  G W+W  +T  SW     RL
Sbjct:  193 PSYLGYRFMGVKDCGAPCEPTKPSGIMYFREDEVKFGRLWVGI---WSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAY----AAGFF-----------LEDKVVCVDKFKGEGFRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGIFNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRI----------------RTIMKHDGTKT--EKLEKLMVR------IGVFSVLYTVPATIVIACYFYEQAFREHWERTWHMQTCKRFAVPCPVHNFAPMTPDFTVFMIKYLMTMIVGITSGFWVWSGKTLQSWRRFYKRL 540
[Close]
BLAST of Fzd-5/8-2 vs. Planmine SMEST
Match: SMESG000053774.1 (SMESG000053774.1)

HSP 1 Score: 1027.31 bits (2655), Expect = 0.000e+0
Identity = 540/540 (100.00%), Postives = 540/540 (100.00%), Query Frame = 3 
Query:  339 FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 1958
            FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS
Sbjct:  187 FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 726
[Close]
BLAST of Fzd-5/8-2 vs. Planmine SMEST
Match: SMESG000053774.1 (SMESG000053774.1)

HSP 1 Score: 1027.31 bits (2655), Expect = 0.000e+0
Identity = 540/540 (100.00%), Postives = 540/540 (100.00%), Query Frame = 3 
Query:  339 FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 1958
            FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS
Sbjct:  183 FDFKSPPTIENHFPINNHSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWLLCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDVMSPNWPIFHS 722
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BLAST of Fzd-5/8-2 vs. Planmine SMEST
Match: SMESG000035834.1 (SMESG000035834.1)

HSP 1 Score: 204.142 bits (518), Expect = 3.462e-56
Identity = 145/406 (35.71%), Postives = 214/406 (52.71%), Query Frame = 3 
Query:  390 HSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNR-YNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQD-SLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLL--CKTKTRNRDT 1595
            +S  +C C CR P+I I  ++  ++N+V T G+ NCA  C+SPF  +      I  WL +   +  +   S + TF ++     + P R + ++  C   +S+GF+IR+V GH    C   DS   +D S L +LR+  S P+ C+I FL  Y+F  A+ LWW LL +TWF   GL W S  I KYSQ+YHF+AWF PGI S++ALTMSAVDGDPV+G+C VGN +  +LI F+L+PL V+   G   L  GF S+ R       RS + +    +T             L KL          G   ++ + P  +    I+YE++ R+ W    +C C +  +    +P PS  +++ KY  F  +G+  G WIW  +T  SW     RL +  C  + RN+ T
Sbjct:  149 NSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRY-RYPERPIIFMSICYFMVSLGFLIRIVMGHEDLAC---DSIKAKDGSSLSLLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRI------RSIIKLQTGGKT-----------EKLEKLMIR------IGVFSVLYTAPAAVIVACIIYELQNRAEWYQNLSCDCFDSNRHQLNLPRPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSWKMVCYRLGINSCHVEERNKHT 527
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BLAST of Fzd-5/8-2 vs. Planmine SMEST
Match: SMESG000035834.1 (SMESG000035834.1)

HSP 1 Score: 204.527 bits (519), Expect = 5.799e-56
Identity = 145/406 (35.71%), Postives = 214/406 (52.71%), Query Frame = 3 
Query:  390 HSNFWCNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNR-YNLIPLWLSISVGLIFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQD-SLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRLLL--CKTKTRNRDT 1595
            +S  +C C CR P+I I  ++  ++N+V T G+ NCA  C+SPF  +      I  WL +   +  +   S + TF ++     + P R + ++  C   +S+GF+IR+V GH    C   DS   +D S L +LR+  S P+ C+I FL  Y+F  A+ LWW LL +TWF   GL W S  I KYSQ+YHF+AWF PGI S++ALTMSAVDGDPV+G+C VGN +  +LI F+L+PL V+   G   L  GF S+ R       RS + +    +T             L KL          G   ++ + P  +    I+YE++ R+ W    +C C +  +    +P PS  +++ KY  F  +G+  G WIW  +T  SW     RL +  C  + RN+ T
Sbjct:  206 NSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRY-RYPERPIIFMSICYFMVSLGFLIRIVMGHEDLAC---DSIKAKDGSSLSLLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRI------RSIIKLQTGGKT-----------EKLEKLMIR------IGVFSVLYTAPAAVIVACIIYELQNRAEWYQNLSCDCFDSNRHQLNLPRPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSWKMVCYRLGINSCHVEERNKHT 584
[Close]
BLAST of Fzd-5/8-2 vs. Planmine SMEST
Match: SMESG000005043.1 (SMESG000005043.1)

HSP 1 Score: 194.897 bits (494), Expect = 2.695e-53
Identity = 154/477 (32.29%), Postives = 228/477 (47.80%), Query Frame = 3 
Query:  405 CNCKCRSPMIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGLIFVCCISS---LLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHYRTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISXXXXXXXXXASVXXXXXXXXXXFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDPVTGLCLVGNINRQHLITFLLAPLCVFTXXXXXXXXXXXXXXXRCDESSANRSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPLFLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGFFAMGIICGPWIWPMQTYNSWLGSIVRL--LLCKTKTRNRDTF-SKPKPPHICQAQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRFPISRLHEIPINHS 1817
            C CKCRSP I  +    P +N V TGG+ANC   C S    +   + +  WL +   L   CC+SS   +LTF+L+R    + P R + ++  C + +S+G+IIR+  GH    C   D           LR+  + P+ CSI FL  YFF  A+ +WW +L +TWF + GL W S  I KYS+++HF+AWF  G+ S+LALT+ A+DGDPV G+C +GN N  +L  FL+ PL V+            L I  C   S   + +SI  + R        ES    L KL          G  GL+ S+P  +  G  +YE++ R  WE ++ C C   I+S      P   +++LKY     +GI  G WIW  +T +SW  +  RL   +C    ++   F    +   +CQ      TN      C  +   Q  L++P T   +L        N   H    +  H + ++ +
Sbjct:  184 CECKCRSPYIYDNK---PQFNSVITGGVANCFQSCHSANFVSIDKSFVTFWLGLWAVL---CCLSSTATVLTFLLDRSRF-KYPERPIVFLSGCYMMVSIGYIIRVAVGHELIAC---DGDK--------LRYGTTGPARCSIVFLLIYFFGMAASVWWVILTITWFLSAGLKWGSEAISKYSEIFHFLAWFLSGVKSILALTLVAIDGDPVGGICYIGNTNSLNLKLFLIVPLTVY------------LLIGSCFLLSGFIALISIRKTIRAKG-----ESKTDKLEKLMMR------IGIFGLLYSVPAAVVIGCHLYEVKNREFWEKSNNCYCNRNIKSQENFSKPEYSVFMLKYFMCLVVGITSGFWIWTSKTLDSWHNAFRRLSQSICGQSDKHTKQFPGNEQETPLCQINSNQITNGKPIEQCLVN---QTALINPATHTGNLYTQHPMDSNALTHHIAGNVQHHLFVHKA 616
The following BLAST results are available for this feature:
BLAST of Fzd-5/8-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FZD81.059e-4529.98frizzled class receptor 8 [Source:HGNC Symbol;Acc:... [more]
FZD55.012e-4431.91frizzled class receptor 5 [Source:HGNC Symbol;Acc:... [more]
FZD21.818e-2028.68frizzled class receptor 2 [Source:HGNC Symbol;Acc:... [more]
FZD17.803e-1928.50frizzled class receptor 1 [Source:HGNC Symbol;Acc:... [more]
FZD31.153e-1725.24frizzled class receptor 3 [Source:HGNC Symbol;Acc:... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cfz-22.288e-2529.01Frizzled-2 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ... [more]
mom-52.529e-1324.87pep chromosome:WBcel235:I:9965580:9970037:1 gene:W... [more]
mom-52.654e-1324.87pep chromosome:WBcel235:I:9965580:9969413:1 gene:W... [more]
lin-179.712e-725.00Transmembrane receptor LIN-17 [Source:UniProtKB/T... [more]
lin-179.712e-725.00Transmembrane receptor LIN-17 [Source:UniProtKB/T... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fz28.036e-4432.07gene:FBgn0016797 transcript:FBtr0112890[more]
fz28.036e-4432.07gene:FBgn0016797 transcript:FBtr0075029[more]
fz28.036e-4432.07gene:FBgn0016797 transcript:FBtr0332735[more]
fz28.036e-4432.07gene:FBgn0016797 transcript:FBtr0330194[more]
fz28.036e-4432.07gene:FBgn0016797 transcript:FBtr0075028[more]
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BLAST of Fzd-5/8-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fzd8b2.679e-5131.30frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GE... [more]
fzd8b7.683e-5131.30frizzled class receptor 8b [Source:ZFIN;Acc:ZDB-GE... [more]
fzd51.100e-5031.35frizzled class receptor 5 [Source:ZFIN;Acc:ZDB-GEN... [more]
fzd8a1.409e-4731.03frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE... [more]
fzd7a8.981e-2027.60frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
zdhhc91.835e-4730.85zinc finger DHHC-type containing 9 [Source:Xenbase... [more]
fzd81.153e-4531.25frizzled class receptor 8 [Source:NCBI gene;Acc:10... [more]
ntrk12.916e-2128.61neurotrophic receptor tyrosine kinase 1 [Source:Xe... [more]
drg15.919e-1724.16developmentally regulated GTP binding protein 1 [S... [more]
FZD49.871e-1727.32frizzled class receptor 4 [Source:NCBI gene;Acc:10... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fzd81.076e-4529.90frizzled class receptor 8 [Source:MGI Symbol;Acc:M... [more]
Fzd52.363e-4331.65frizzled class receptor 5 [Source:MGI Symbol;Acc:M... [more]
Fzd52.363e-4331.65frizzled class receptor 5 [Source:MGI Symbol;Acc:M... [more]
Fzd21.240e-2028.68frizzled class receptor 2 [Source:MGI Symbol;Acc:M... [more]
Fzd101.022e-1827.70frizzled class receptor 10 [Source:MGI Symbol;Acc:... [more]
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BLAST of Fzd-5/8-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P58421|FZD5_XENLA9.080e-4731.12Frizzled-5 OS=Xenopus laevis OX=8355 GN=fzd5 PE=2 ... [more]
sp|O93274|FZD8_XENLA4.073e-4631.77Frizzled-8 OS=Xenopus laevis OX=8355 GN=fzd8 PE=1 ... [more]
sp|Q9H461|FZD8_HUMAN5.084e-4529.98Frizzled-8 OS=Homo sapiens OX=9606 GN=FZD8 PE=1 SV... [more]
sp|Q61091|FZD8_MOUSE7.528e-4529.90Frizzled-8 OS=Mus musculus OX=10090 GN=Fzd8 PE=1 S... [more]
sp|Q498S8|FZD8_RAT1.132e-4329.90Frizzled-8 OS=Rattus norvegicus OX=10116 GN=Fzd8 P... [more]
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BLAST of Fzd-5/8-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1E1C50.000e+099.26Fzd-5/8-2 (Fragment) OS=Schmidtea mediterranea OX=... [more]
A0A1S6KMG80.000e+099.22G_PROTEIN_RECEP_F2_4 domain-containing protein OS=... [more]
Q589S50.000e+080.59Frizzled receptor OS=Dugesia japonica OX=6161 GN=D... [more]
T1DBM92.022e-17162.63Fzd-5/8-2 (Fragment) OS=Dendrocoelum lacteum OX=27... [more]
T1DF425.685e-5235.31Fzd-5/8-3 OS=Schmidtea mediterranea OX=79327 PE=2 ... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000026985.23.624e-5131.12pep primary_assembly:Astyanax_mexicanus-2.0:19:270... [more]
fzd8a1.791e-4931.07frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE... [more]
fzd42.237e-1825.33frizzled class receptor 4 [Source:NCBI gene;Acc:10... [more]
fzd7b2.310e-1826.55frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GE... [more]
fzd9a1.664e-1726.86frizzled class receptor 9a [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fzd8a8.282e-4431.09frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000011009.11.117e-4331.59pep scaffold:Pmarinus_7.0:GL485859:2701:4509:1 gen... [more]
fzd7a2.333e-2029.29frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GE... [more]
fzd22.948e-1827.62frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
fzd3b1.153e-1024.17frizzled class receptor 3b [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Fzd-5/8-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO429321.279e-3431.59Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO385676.105e-2827.36Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO357512.385e-2528.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308651.934e-1727.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Fzd-5/8-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000013002.21.839e-4931.70pep primary_assembly:ASM223467v1:21:5638676:564429... [more]
fzd8a1.803e-4430.95frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GE... [more]
ENSORLT00000002667.22.931e-4431.12pep primary_assembly:ASM223467v1:17:316235:318512:... [more]
fzd21.183e-1927.46frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GEN... [more]
fzd7b3.800e-1927.18frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Fzd-5/8-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053774.10.000e+0100.00SMESG000053774.1[more]
SMESG000053774.10.000e+0100.00SMESG000053774.1[more]
SMESG000035834.13.462e-5635.71SMESG000035834.1[more]
SMESG000035834.15.799e-5635.71SMESG000035834.1[more]
SMESG000005043.12.695e-5332.29SMESG000005043.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025972 ID=SMED30025972|Name=Fzd-5/8-2|organism=Schmidtea mediterranea sexual|type=transcript|length=2144bp
TCGCTCATGGGTATACAGTGGTAATGTCAAAATTGTGGGGCGTCTGGGAG
AGAAACCCTAGAAAAGCAAGAGTGATTAAAGAAAAAGAGTTAACAAATGC
GCATCGATTAAAACAAAATTAATTCTACCCAGTGCGCCAGCACTTATTGT
ATAACAACTCCATAATAACGATAATAAGATTAATATTATAATGATGGTAA
CCGAAATAACAAACCACGGTATGAGATTAATAATAACGATAATCATAATA
ATAATGATGATAACCCAAATGATCAGATCAAGGTGATAATAATAATCACA
ATACTAATAATAATAATAATATTAACAACAATATTGATTTTGATTTCAAA
TCCCCACCGACAATTGAAAATCATTTCCCAATCAATAATCACTCAAATTT
TTGGTGCAATTGTAAGTGCAGATCTCCAATGATAAAAATCGATTCGGTTC
ATCATCCATATTATAATAAGGTTCACACGGGAGGACTTGCCAACTGTGCT
TGGCCTTGTCGGTCGCCGTTTATTGAGAACAATCGTTACAATCTCATTCC
GTTATGGTTAAGCATTTCTGTGGGTCTCATATTTGTCTGTTGCATTTCAA
GCCTGTTGACATTCGTTTTGAATCGAGTTGAACTCATTCAGCCTCCCCAT
AGATTCGTAGCGTATATTTGCTGTTGTCAAATCGGTATGAGCGTCGGTTT
CATTATCCGATTGGTTGCCGGTCACTATCGCACAGTTTGTTTTCAGCCTG
ACTCCAAACCAATACAAGACTCATTGCTTTTGATGCTGAGATTTCAGAAT
TCTGCACCTTCAGTTTGCAGTATCAGTTTTCTGTTCACCTACTTTTTTTT
CTTTGCGTCTGTGTTATGGTGGTGGTTGCTTTGTCTCACTTGGTTTTTTA
ATGATGGATTGGGATGGTCAAGTTCCATGATCGACAAATATTCACAGCTT
TATCATTTCATCGCTTGGTTTTTCCCTGGAATATTCAGCATGCTAGCGCT
GACAATGAGTGCTGTCGACGGAGATCCGGTAACTGGGCTTTGCCTCGTTG
GAAATATCAACCGACAACATTTGATCACATTTTTACTTGCTCCTCTCTGT
GTGTTTACTTGTTCCGGTTTCTTTTTTCTTGGATGTGGATTTCTCAGTAT
AATACGATGTGATGAGTCTTCAGCAAACCGATCAAAATTGTCGATTCCCG
TTTCACCAAGAACAATTTCAACCGATACCTCAGTCGAATCCGCAGCTTCG
TCGCTGCCAAAGCTAACTACCTCTAATATCACAAAATTCTTTTATGGTTT
CCTTGGGTTGATTTGTTCAATACCCCTTTTTTTGACAACAGGGAGTATTG
TTTATGAAATGCGATGGCGATCTCATTGGGAATTAGCCTCAACTTGTACT
TGTTTAAATCAAATCCAATCCAATTCATACATACCAACTCCAAGCATTTT
GTTATACGTATTAAAATACTCTGGTTTTTTTGCCATGGGCATAATTTGTG
GCCCTTGGATTTGGCCTATGCAAACTTATAATTCTTGGCTGGGTTCAATT
GTTCGTTTGTTATTATGTAAAACTAAAACAAGAAACAGAGATACTTTTAG
TAAACCAAAGCCTCCTCATATTTGCCAAGCGCAACAGCTGTACAATACAA
ACTATACGATAACAACTTCATGTCCAACCTCCTGCCAAAGACAGGAATGC
TTATTAGATCCGCCAACCATAAACGACTCTTTAATTATGTCCAGTTTAAA
TCCTATGAATAAATGCCAGCATAGATTTCCTATCTCAAGGCTACATGAAA
TTCCTATCAATCATTCGATAGCTCCAGATGCAGAGTCTTATGCATCATAT
CAATCCCTTTCAAATTATCATCTCAATCAGTTCAAAAACCCTCAAAACCT
TTATGAATTTTACAAAAAGGACGATGTCATGTCGCCAAATTGGCCAATTT
TTCATTCGTAATATCTCAGCTTTCTATTAACATATCAGCATATTTAAACT
CTTCACTAAAACAACTCACAGGGTCTGTACAATGTACACTGTACATATAT
TCAAACGGGCATAGCGTCTAGGTTTGTCTTTTCTCTCTTATATAAAATGT
ATCATAAACTATTATTTTTATTCAAGATTTTGAGGCTTTTTTAC
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protein sequence of SMED30025972-orf-1

>SMED30025972-orf-1 ID=SMED30025972-orf-1|Name=SMED30025972-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=511bp
MIKIDSVHHPYYNKVHTGGLANCAWPCRSPFIENNRYNLIPLWLSISVGL
IFVCCISSLLTFVLNRVELIQPPHRFVAYICCCQIGMSVGFIIRLVAGHY
RTVCFQPDSKPIQDSLLLMLRFQNSAPSVCSISFLFTYFFFFASVLWWWL
LCLTWFFNDGLGWSSSMIDKYSQLYHFIAWFFPGIFSMLALTMSAVDGDP
VTGLCLVGNINRQHLITFLLAPLCVFTCSGFFFLGCGFLSIIRCDESSAN
RSKLSIPVSPRTISTDTSVESAASSLPKLTTSNITKFFYGFLGLICSIPL
FLTTGSIVYEMRWRSHWELASTCTCLNQIQSNSYIPTPSILLYVLKYSGF
FAMGIICGPWIWPMQTYNSWLGSIVRLLLCKTKTRNRDTFSKPKPPHICQ
AQQLYNTNYTITTSCPTSCQRQECLLDPPTINDSLIMSSLNPMNKCQHRF
PISRLHEIPINHSIAPDAESYASYQSLSNYHLNQFKNPQNLYEFYKKDDV
MSPNWPIFHS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR015526Frizzled/SFRP
IPR000539Frizzled/Smoothened_TM
IPR017981GPCR_2-like
Vocabulary: biological process
TermDefinition
GO:0007166cell surface receptor signaling pathway
GO:0016055Wnt signaling pathway
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO:0042813Wnt-activated receptor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000539Frizzled/Smoothened, transmembrane domainPRINTSPR00489FRIZZLEDcoord: 220..242
score: 39.83
coord: 72..94
score: 24.87
coord: 43..65
score: 20.17
coord: 132..156
score: 49.76
coord: 175..198
score: 35.67
coord: 342..362
score: 32.38
IPR000539Frizzled/Smoothened, transmembrane domainSMARTSM01330Frizzled_2coord: 30..380
e-value: 3.6E-49
score: 179.3
IPR000539Frizzled/Smoothened, transmembrane domainPFAMPF01534Frizzledcoord: 34..372
e-value: 1.2E-61
score: 208.6
NoneNo IPR availableGENE3DG3DSA:1.20.1070.10coord: 4..378
e-value: 8.2E-77
score: 260.3
NoneNo IPR availablePANTHERPTHR11309:SF90FRIZZLED-8coord: 291..377
NoneNo IPR availablePANTHERPTHR11309:SF90FRIZZLED-8coord: 1..244
NoneNo IPR availableCDDcd139517tmF_Frizzled_SMOcoord: 30..370
e-value: 2.68096E-83
score: 258.788
NoneNo IPR availableTMHMMTMhelixcoord: 174..196
NoneNo IPR availableTMHMMTMhelixcoord: 287..309
NoneNo IPR availableTMHMMTMhelixcoord: 76..98
NoneNo IPR availableTMHMMTMhelixcoord: 131..153
NoneNo IPR availableTMHMMTMhelixcoord: 216..238
NoneNo IPR availableTMHMMTMhelixcoord: 42..64
NoneNo IPR availableTMHMMTMhelixcoord: 340..362
IPR015526Frizzled/secreted frizzled-related proteinPANTHERPTHR11309FRIZZLEDcoord: 291..377
IPR015526Frizzled/secreted frizzled-related proteinPANTHERPTHR11309FRIZZLEDcoord: 1..244
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 40..243
score: 23.36