TNF receptor-associated factor
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025971 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 121.324 bits (303), Expect = 2.565e-28 Identity = 103/413 (24.94%), Postives = 190/413 (46.00%), Query Frame = 3
Query: 294 LKTYLNRSEKFCPGDSDYCKR--VLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNY-ATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQ--KSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
LK +L+ S +F YCK+ V+IN N+ + + CP C ++ +++EH+ +C + CPF + GC + N++QH S + H L+++ N + +I S++ + ++I+++ E I + + ++ F K FL VF ++ + ++ + +++ ++N+ + V+ + KI N+QR+ E + + H + KA++ +NE W + ++ K+ A G IFS F + GY+L +A NG G+ +LS+Y +M+G D+ L WPF+ VT +++Q K N++ T+ PNS + RP NI G P F++ LE + I D+ + LK V L
Sbjct: 153 LKEHLSASCQFRKEKCLYCKKDVVVINLQNH------EENLCPEYPVFCPNNCAKIILK-TEVDEHLAVCPEAEQDCPFKHYGCAVTD-KRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHIN-IHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIME-----TFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551 HSP 2 Score: 86.2705 bits (212), Expect = 5.799e-17 Identity = 43/151 (28.48%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS-MNPGLIVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + IFS+ FY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ + ++ F D P+ + RP E ++ G +F++ L I DD + +V ++
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPD--PNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 121.324 bits (303), Expect = 2.565e-28 Identity = 103/413 (24.94%), Postives = 190/413 (46.00%), Query Frame = 3
Query: 294 LKTYLNRSEKFCPGDSDYCKR--VLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNY-ATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQ--KSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
LK +L+ S +F YCK+ V+IN N+ + + CP C ++ +++EH+ +C + CPF + GC + N++QH S + H L+++ N + +I S++ + ++I+++ E I + + ++ F K FL VF ++ + ++ + +++ ++N+ + V+ + KI N+QR+ E + + H + KA++ +NE W + ++ K+ A G IFS F + GY+L +A NG G+ +LS+Y +M+G D+ L WPF+ VT +++Q K N++ T+ PNS + RP NI G P F++ LE + I D+ + LK V L
Sbjct: 153 LKEHLSASCQFRKEKCLYCKKDVVVINLQNH------EENLCPEYPVFCPNNCAKIILK-TEVDEHLAVCPEAEQDCPFKHYGCAVTD-KRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHIN-IHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIME-----TFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551 HSP 2 Score: 86.2705 bits (212), Expect = 5.799e-17 Identity = 43/151 (28.48%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS-MNPGLIVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + IFS+ FY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ + ++ F D P+ + RP E ++ G +F++ L I DD + +V ++
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPD--PNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF5 (TNF receptor associated factor 5 [Source:HGNC Symbol;Acc:HGNC:12035]) HSP 1 Score: 121.324 bits (303), Expect = 2.565e-28 Identity = 103/413 (24.94%), Postives = 190/413 (46.00%), Query Frame = 3
Query: 294 LKTYLNRSEKFCPGDSDYCKR--VLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNY-ATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQ--KSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
LK +L+ S +F YCK+ V+IN N+ + + CP C ++ +++EH+ +C + CPF + GC + N++QH S + H L+++ N + +I S++ + ++I+++ E I + + ++ F K FL VF ++ + ++ + +++ ++N+ + V+ + KI N+QR+ E + + H + KA++ +NE W + ++ K+ A G IFS F + GY+L +A NG G+ +LS+Y +M+G D+ L WPF+ VT +++Q K N++ T+ PNS + RP NI G P F++ LE + I D+ + LK V L
Sbjct: 153 LKEHLSASCQFRKEKCLYCKKDVVVINLQNH------EENLCPEYPVFCPNNCAKIILK-TEVDEHLAVCPEAEQDCPFKHYGCAVTD-KRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHIN-IHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIME-----TFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551 HSP 2 Score: 86.2705 bits (212), Expect = 5.799e-17 Identity = 43/151 (28.48%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS-MNPGLIVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + IFS+ FY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ + ++ F D P+ + RP E ++ G +F++ L I DD + +V ++
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPD--PNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF2 (TNF receptor associated factor 2 [Source:HGNC Symbol;Acc:HGNC:12032]) HSP 1 Score: 105.145 bits (261), Expect = 3.940e-23 Identity = 84/356 (23.60%), Postives = 151/356 (42.42%), Query Frame = 3
Query: 390 DQPTNHRIA-RLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYAT-KIPIIRTILHNEE--NQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
D +H + + L C + CG I + ++H++ C R C F IGC E + ++H + + H ++L+ K + + +E+ + E + + + F + +LN ++ + + +Q I +KV+++ I + + LEQ++ E A + F W I +F+ KR+ A +G++ IFS F + GY++ + NG G +LS++ +MKG ND L WPF VT +++Q +N H D+ S + RP NI G P F ++E + + D+ I +K V L G
Sbjct: 174 DVKAHHEVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLET-VEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKT------------------ATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIG---LKDLAMADLEQKVLEME---ASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDV--TSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG 500 HSP 2 Score: 93.2041 bits (230), Expect = 2.545e-19 Identity = 47/147 (31.97%), Postives = 77/147 (52.38%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +F + R++A +G+ IFS FY+ R GYKM L +Y NG TG +S++F ++KGP+D L WP+ V L+DQ+ N V++ F D+ + RP + ++ G F K+ + DD I + ++
Sbjct: 355 IWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDVTSS--SFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. Ensembl Human
Match: TRAF6 (TNF receptor associated factor 6 [Source:HGNC Symbol;Acc:HGNC:12036]) HSP 1 Score: 92.0485 bits (227), Expect = 6.603e-19 Identity = 101/459 (22.00%), Postives = 184/459 (40.09%), Query Frame = 3
Query: 171 LRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCP---------FINI----GCQENNLVVLNMKQHL-LSEIEVHS--------------SLLMQWNENTKNEIDSIKNQVN---EIKEIKEKINRNS-RRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNE----FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPN-GSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNI-GVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
++ Y+ E + + +C IC + A +PCG RFC C+ + + CP D++ I +N +F D I L +KCP +EL +E+H C CP INI C + N + + E+H ++L++ ++D + EK+ RN R L M+ L + + Y +++ + +H E ++ + + + E+ K+ Q + E L++ I T E AE+ + + W I NF + + K I S F + + GY+L + + Y+S+++ M+G D++L WPF+ + +I++Q V D P + RPT RN G G+ +F+ + L +T I D+ ++++C+V
Sbjct: 53 IQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNE------ILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQ--IRELTAKMETQSMYVSE---LKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRT-FIKDDTLLVRCEV 499 HSP 2 Score: 57.3806 bits (137), Expect = 5.683e-8 Identity = 46/188 (24.47%), Postives = 86/188 (45.74%), Query Frame = 3
Query: 1374 ELETQTGLIVDNRIILKCKVHLDGKLANTLHENGNKI-IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELY---PNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNR---NRPFTEKSL-GFGFEKFISFEKLSMNPGLIVDDKIAFRV 1913
++ETQ+ + + + ++ L+ K+A + N I IW + NF K + K + I S FY+ + GYK+ + L+ P +S++ ++G +D L WP++ + ++DQ A V + ++++ P RP ++ GFG+ F+ E L I DD + R
Sbjct: 319 KMETQSMYVSELKRTIR---TLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCA--NYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSE---APVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQR-TFIKDDTLLVRC 497
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586]) HSP 1 Score: 81.6481 bits (200), Expect = 1.407e-16 Identity = 57/186 (30.65%), Postives = 92/186 (49.46%), Query Frame = 3
Query: 888 IVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVY-EIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEW-NRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHL 1439
I KIN Q+ + Y + + ++ E + ++ T+ I A K + I+S PF SH GY++M A P G G Y S+++C+MKG D+ L WPF+ +VTFSI++ + +K + +M P +E+ RP RN GF +F+ ++ T D I ++ KV L
Sbjct: 124 IRTKINIQQSAYVDKYVGMLQYMSIAESAFEKYGSQHTFRIPKIGLTVVKATKNKSHRSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKELLTKTIYVNEM-PEIQEFLERPEGLRNGTFGFQNFLPLAKV---TEFAADGDIFIQIKVLL 305 HSP 2 Score: 64.3142 bits (155), Expect = 7.395e-11 Identity = 32/107 (29.91%), Postives = 54/107 (50.47%), Query Frame = 3
Query: 1548 IFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS 1868
I+S+PFYSH GYKM+ P G E S++ ++KG DD LEWP++ +V F ++ + +++ RP ++ FGF+ F+ K++
Sbjct: 183 IYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILSDDKKELLTKTIYVNEMPEIQEFLERPEGLRNGTFGFQNFLPLAKVT 289
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80]) HSP 1 Score: 78.5666 bits (192), Expect = 3.951e-15 Identity = 50/153 (32.68%), Postives = 73/153 (47.71%), Query Frame = 3
Query: 942 EQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRL-LTYDMLP-----NSKEWNRPTQFRNIGVGFPSFISFKELE 1382
+ I ++ +T EM + W I + AKSG IFS PF+SH GY++M A G G+ +S+Y+ ++KG D L WPF + S+++Q N R+ +TY + P N K RP RN G SF S L+
Sbjct: 247 QTRILSAAETCTEMFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQ--NPRPEDRVNITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCSLAILQ 397 HSP 2 Score: 77.411 bits (189), Expect = 9.325e-15 Identity = 49/155 (31.61%), Postives = 75/155 (48.39%), Query Frame = 3
Query: 1473 GNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRN-----RPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTE 1922
G ++IW + Q +A+SG IFS PF SHR GYKM+ G + + +S+Y ++KG D LEWP+ + L+DQ+ VN T + P N RP E++ FG + F S L++ + DDKI ++ +
Sbjct: 262 GPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLDQNPRPEDRVN-ITYVIDPRKLKANEKFLARPRGERNAAFGSQSFCS---LAILQNYVKDDKIYVQIDVD 412
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0077429) HSP 1 Score: 88.5817 bits (218), Expect = 4.011e-18 Identity = 49/153 (32.03%), Postives = 78/153 (50.98%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQ--HTNYPAVVNKFTDDLLPDHPNRNRPFTEKS-LGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQK 1931
++W + +++ +A+ L++ S PFY+ + GYK+ ++ NG G N VS+Y +++ G +D L+WP+ ++ F L +Q + V F D P N RP E LGFGF +FIS E L P I D + RV + K
Sbjct: 333 LLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPD--PTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVDPSK 482 HSP 2 Score: 75.485 bits (184), Expect = 5.309e-14 Identity = 44/145 (30.34%), Postives = 75/145 (51.72%), Query Frame = 3
Query: 1002 WTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPT-QFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
W I ++S K A+ E+ S PF + + GY+L NG+G EN ++S+YI ++ G D L WPF ++TF++ Q + ++ P + + RP+ + +G GFP FIS + L ++ I + + L+ KV
Sbjct: 335 WKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKV 478
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf4 (gene:FBgn0026319 transcript:FBtr0334401) HSP 1 Score: 88.1965 bits (217), Expect = 4.914e-18 Identity = 49/153 (32.03%), Postives = 78/153 (50.98%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQ--HTNYPAVVNKFTDDLLPDHPNRNRPFTEKS-LGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQK 1931
++W + +++ +A+ L++ S PFY+ + GYK+ ++ NG G N VS+Y +++ G +D L+WP+ ++ F L +Q + V F D P N RP E LGFGF +FIS E L P I D + RV + K
Sbjct: 324 LLWKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPD--PTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKVDPSK 473 HSP 2 Score: 76.2554 bits (186), Expect = 2.929e-14 Identity = 44/145 (30.34%), Postives = 75/145 (51.72%), Query Frame = 3
Query: 1002 WTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPT-QFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
W I ++S K A+ E+ S PF + + GY+L NG+G EN ++S+YI ++ G D L WPF ++TF++ Q + ++ P + + RP+ + +G GFP FIS + L ++ I + + L+ KV
Sbjct: 326 WKITDWSAKMAEARGKDGLELVSPPFYTSQYGYKLQASMFLNGNGPGENTHVSVYIKVLPGEYDALLKWPFSHSITFTLFEQGAQSGQGGVAESFVPDPTWENFQRPSNEPDQLGFGFPRFISHELLHSRP-FIKGDTVFLRVKV 469
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Match: Traf6 (gene:FBgn0265464 transcript:FBtr0071188) HSP 1 Score: 51.2174 bits (121), Expect = 2.627e-6 Identity = 68/347 (19.60%), Postives = 131/347 (37.75%), Query Frame = 3
Query: 219 KCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQME--EHIRICNNQRR------FCPFINIGCQENNLVVLN-MKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTF 1232
+C IC + + CG RFC CL ++ ++ + CP D+ KR ++ ++++F D T I +L+ CP + + + +E H+ C +R+ CPF I C N +++HL +++ H L++Q + T ++ + Y + +V T Y I+ + T L N + Q+ + + V+ R +N W I ++ +++S + +GY+ F A N ++ LS+++ +M+ ND +L WPFK +
Sbjct: 103 ECAICIDWLNEPVLTSCGHRFCRSCLTAWMQKNNQCCPMDN---KR--LSAEHDIFPDNYTRREIEQLKRDCPNSSLGCSVVASPIELHRHLPSCPYRRQQEPQEEKCPFAKIKCDFVGRPETNQLEEHLKADMPHHMQLMLQAFQQTAIATWQPHKPSTSGAAVENGHGQQQLPPPPQY----ANGVDEQIVQTMYQRIVVLEQRTREQETRLENMQKQLRLARQQAPVDP--------RYSN----------------------GTIVWRIEQLGALVARLRANANNQVYSHECYTSPHGYK--FCARLNIQPRKPHV-LSLHVHLMQSENDYHLDWPFKGRIKL 407
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 100.523 bits (249), Expect = 5.581e-22 Identity = 59/164 (35.98%), Postives = 89/164 (54.27%), Query Frame = 3
Query: 984 HQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
H W + ++S K + AK +E FS PF +H GY+L A NG+G+ E +LSIYI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P RN +G G+P FIS +E++ + I DN I LK + + K+
Sbjct: 306 HDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRN-YIRDNSIFLKASIEIPQKI 468 HSP 2 Score: 90.1225 bits (222), Expect = 1.426e-18 Identity = 49/159 (30.82%), Postives = 85/159 (53.46%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +SIY +++ G +D+ LEWP+ V F ++DQ + T+ PD P +R E +LGFG+ KFIS E++ I D+ I + + E+ +K
Sbjct: 310 LIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKR-NYIRDNSIFLKASIEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf4a (tnf receptor-associated factor 4a [Source:ZFIN;Acc:ZDB-GENE-040308-1]) HSP 1 Score: 100.523 bits (249), Expect = 5.581e-22 Identity = 59/164 (35.98%), Postives = 89/164 (54.27%), Query Frame = 3
Query: 984 HQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
H W + ++S K + AK +E FS PF +H GY+L A NG+G+ E +LSIYI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P RN +G G+P FIS +E++ + I DN I LK + + K+
Sbjct: 306 HDGVLIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKRN-YIRDNSIFLKASIEIPQKI 468 HSP 2 Score: 90.1225 bits (222), Expect = 1.426e-18 Identity = 49/159 (30.82%), Postives = 85/159 (53.46%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +SIY +++ G +D+ LEWP+ V F ++DQ + T+ PD P +R E +LGFG+ KFIS E++ I D+ I + + E+ +K
Sbjct: 310 LIWKLTDYSRKLQEAKLRNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSSRNSLDESTLGFGYPKFISHEEIKKR-NYIRDNSIFLKASIEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: unm_sa808 (un-named sa808 [Source:ZFIN;Acc:ZDB-GENE-120727-21]) HSP 1 Score: 95.1301 bits (235), Expect = 3.354e-21 Identity = 60/201 (29.85%), Postives = 94/201 (46.77%), Query Frame = 3
Query: 876 KVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMH-----------QNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
K+E + NK+ QLE+++ + T AEM F W I +F+ KR++A +G+ +FS F + + GY++ + NG G +LS++ +M+G +D L WPF VT +++Q SN H D+ S + RP NI G P F +LE + I D+ I +K V L G
Sbjct: 93 KIEALSNKVR----------QLERQVGVKDLTVAEMEGRLREMSATTFDGVFIWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQ-SNREHIIDAFRPDI--TSSSFQRPVSEMNIASGCPLFCPLAKLEGKNSYIRDDTIFIKAIVDLTG 280 HSP 2 Score: 93.2041 bits (230), Expect = 1.369e-20 Identity = 48/147 (32.65%), Postives = 79/147 (53.74%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +FT+ R+DA +G+A +FS FY+ + GYKM L +Y NG TG +S++F +++G D L+WP+ V L+DQ +N +++ F D+ + RP +E ++ G F KL I DD I + ++
Sbjct: 135 IWRISDFTKKRQDAIAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGMSDALLKWPFNQKVTLMLLDQ-SNREHIIDAFRPDITSS--SFQRPVSEMNIASGCPLFCPLAKLEGKNSYIRDDTIFIKAIVDL 278
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 98.5969 bits (244), Expect = 3.728e-21 Identity = 49/147 (33.33%), Postives = 80/147 (54.42%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + F++ R+DA +G+A +FS FYS + GYKM L LY NG TG +S++F ++KG +D L+WP+ V L+DQ+ N +++ F D+ + RP +E ++ G F KL+ + DD I + ++
Sbjct: 386 IWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDV--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDL 529 HSP 2 Score: 97.8265 bits (242), Expect = 6.590e-21 Identity = 86/346 (24.86%), Postives = 141/346 (40.75%), Query Frame = 3
Query: 444 CGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQ--HLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQM---------KFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINN-QRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
CG I + +EH + C + C F IGC+ VV N KQ H + I H L++ + S++ + E +E + R P K + +LN + R+ L E + K+E + NK+ +R QL + + + + + F W I FS +R++A +G+ +FS F S + GY++ + NG G +LS++ +MKG D L WPF VT +++Q +N H D+ +S + RP NI G P F +L ++ + D+ I +K V L G
Sbjct: 203 CGKKKIPREKFQEHTKSCAKSKSACQFREIGCRA---VVDNCKQQEHEQTSIMEHLRLMLAL-------LSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVE----RSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDV--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTG 531
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Match: traf2b (Tnf receptor-associated factor 2b [Source:ZFIN;Acc:ZDB-GENE-030131-5345]) HSP 1 Score: 98.5969 bits (244), Expect = 3.728e-21 Identity = 49/147 (33.33%), Postives = 80/147 (54.42%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + F++ R+DA +G+A +FS FYS + GYKM L LY NG TG +S++F ++KG +D L+WP+ V L+DQ+ N +++ F D+ + RP +E ++ G F KL+ + DD I + ++
Sbjct: 386 IWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDV--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDL 529 HSP 2 Score: 97.8265 bits (242), Expect = 6.590e-21 Identity = 86/346 (24.86%), Postives = 141/346 (40.75%), Query Frame = 3
Query: 444 CGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQ--HLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQM---------KFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINN-QRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
CG I + +EH + C + C F IGC+ VV N KQ H + I H L++ + S++ + E +E + R P K + +LN + R+ L E + K+E + NK+ +R QL + + + + + F W I FS +R++A +G+ +FS F S + GY++ + NG G +LS++ +MKG D L WPF VT +++Q +N H D+ +S + RP NI G P F +L ++ + D+ I +K V L G
Sbjct: 203 CGKKKIPREKFQEHTKSCAKSKSACQFREIGCRA---VVDNCKQQEHEQTSIMEHLRLMLAL-------LSSMRLRAEGAGEWQEDVGLGLYRGPEDAPPAGAHNVGRGGGPGVQKKVTTLENIVCVLNKEVE----RSALTMEAISRQHRLDQEKIENLSNKVRQLERTLTTRDLQLAESEQSLRELQFCTYDGVFIWKIAEFSRRRQDAVAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMKGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDV--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTG 531
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: sytl2 (synaptotagmin like 2 [Source:Xenbase;Acc:XB-GENE-945155]) HSP 1 Score: 100.138 bits (248), Expect = 1.249e-21 Identity = 57/158 (36.08%), Postives = 89/158 (56.33%), Query Frame = 3
Query: 1002 WTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
W I ++S K + AK +E FS PF +H+ GY+L A NG+G+ E YLS+YI ++ G DN L WPF VTFS+++Q + + + T++ PN K + +PT RN +G G+P FIS +++ + + DN I L+ V + K+
Sbjct: 312 WKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIRKRN-YVRDNAIFLRASVEIPQKI 468 HSP 2 Score: 91.6633 bits (226), Expect = 5.807e-19 Identity = 48/159 (30.19%), Postives = 84/159 (52.83%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+H+ GYK+ + + NG +G +S+Y +++ G +D+ LEWP+ V F L+DQ + T+ PD P +R E +LGFG+ KFIS E + + D+ I R + E+ +K
Sbjct: 310 LIWKISDYSRKVQEAKVRGNFESFSPPFYTHKYGYKLQVSAFLNGNGSGEGSYLSVYIRVLPGEYDNLLEWPFSYRVTFSLLDQSDPSLSKPQHITETFNPDPNWKNFQKPTGSRNSLDESTLGFGYPKFISHEDIRKR-NYVRDNAIFLRASVEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 98.5969 bits (244), Expect = 5.003e-21 Identity = 83/324 (25.62%), Postives = 143/324 (44.14%), Query Frame = 3
Query: 471 QMEEHIRICNNQRRFCPFINIGCQENNLVVL--NMKQHLL---SEIEVHSSLLMQWNENTKNE-----IDSIKNQVNEIKEIKEKINRN-----SRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKI---PIIRTILHNEENQISIYEFKTKVEEIVNKINNQRI--NNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE 1382
Q+++H+ C C F N GC N++VL ++ H L + V L +Q N + K D++K E + + N S + L SY K M +L L+ +++ PI+ T+ ++ ++ +K +++ + + + +N++ Q+ + + + W I ++ K+ A G+ IFS F + GY+L +A NG G+ + +LS+Y +MKG D+ LLWPFK VT +++Q H + D PNS + RP NI G P F S +LE
Sbjct: 199 QLDKHLCECPEAELQCTFSNYGC---NVMVLYHSLSVHFLYLCTFTSVSQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSM-----WLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHK-MQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLE 511 HSP 2 Score: 91.2781 bits (225), Expect = 1.087e-18 Identity = 45/152 (29.61%), Postives = 80/152 (52.63%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS--MNPGLIVDDKIAFRVTTEV 1925
K+IW + ++ + +++A G+A+ IFS+ FY+ GY++ Y NG +G +S+YF ++KG D L WP+K V L+DQ + + F D P+ + RP +E ++ G +F S +L N I DD + ++ ++
Sbjct: 383 GKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVDL 532
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 96.2857 bits (238), Expect = 2.099e-20 Identity = 83/347 (23.92%), Postives = 147/347 (42.36%), Query Frame = 3
Query: 432 CPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVN------EIKEIKEKI-------------------NRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKI---PIIRTILHNEENQISIYEFKTKVEEIVNKINNQRI--NNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE 1382
CP TC ++++H+ C C F N GC N++V K + + +L N N K E + Q N +I+++ + + + +S + L SY K M +L L+ +++ PI+ T+ ++ ++ +K +++ + + + +N++ Q+ + + + W I ++ K+ A G+ IFS F + GY+L +A NG G+ + +LS+Y +MKG D+ LLWPFK VT +++Q H + D PNS + RP NI G P F S +LE
Sbjct: 131 CPVTC-----PRAELDKHLCECPEAELQCTFSNYGC---NVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLGLQQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSM-----WLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHK-MQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLE 461 HSP 2 Score: 90.5077 bits (223), Expect = 1.477e-18 Identity = 45/152 (29.61%), Postives = 80/152 (52.63%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS--MNPGLIVDDKIAFRVTTEV 1925
K+IW + ++ + +++A G+A+ IFS+ FY+ GY++ Y NG +G +S+YF ++KG D L WP+K V L+DQ + + F D P+ + RP +E ++ G +F S +L N I DD + ++ ++
Sbjct: 333 GKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVDL 482
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: slc12a1 (solute carrier family 12 member 1 [Source:Xenbase;Acc:XB-GENE-479925]) HSP 1 Score: 96.2857 bits (238), Expect = 2.623e-20 Identity = 107/481 (22.25%), Postives = 184/481 (38.25%), Query Frame = 3
Query: 219 KCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEK-FCPGD-----------SDYCKRVLINF----DNNVFCD---------QPTNHRIARLRLKCPETCGDDFI--ELN------------------------------------QMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNE---------IDSIKNQVNEIKEIKEKINR----------------NSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKI---PIIRTILHNEENQISIYEFKTKVEEIVNKINNQRI--NNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE 1382
KC C ++ N + CG RFC C+ + SE CP D + CKR ++N N+ CD + + + L + C D I EL Q+++H+ C C F N GC N++V K + + +L N N K E +D ++Q+ ++ + + + +S + L SY K M +L L+ +++ PI+ T+ ++ ++ +K +++ + + + +N++ Q+ + + + W I ++ K+ A G+ IFS F + GY+L +A NG G+ + +LS+Y +MKG D+ LLWPFK VT +++Q H + D PNS + RP NI G P F S +LE
Sbjct: 43 KCASCHLVLHNPHQTGCGHRFCEKCISNLIELSETPQCPIDMENIKSHEIFKDNCCKREVLNLLVYCKNSPACDVKVMLGRYQEHLGQCLYEMTLCSNDGCHDQMIRKELKGHLESECKLRQEACIYCKQTMSFNHENNYKKIFFSFQLDKHLCECPEAELQCTFSNYGC---NVMVKRGKVKEHEDTFLRDHMLYVLNRNMKLEEQVLSVLQNLDLKEHQIQQLSDTVKWCEKECHQFGQFTGSNGNSLSSTKTLASYIDKSM-----WLEEQVIQLVSKEHSRLDLRPILDTLESTKQRLSTLEAYKDRIDNLDGQFKKHDVLLSNHK-MQMTSNEERFRLVEGTSYNGKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLE 512 HSP 2 Score: 90.8929 bits (224), Expect = 1.624e-18 Identity = 45/152 (29.61%), Postives = 80/152 (52.63%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS--MNPGLIVDDKIAFRVTTEV 1925
K+IW + ++ + +++A G+A+ IFS+ FY+ GY++ Y NG +G +S+YF ++KG D L WP+K V L+DQ + + F D P+ + RP +E ++ G +F S +L N I DD + ++ ++
Sbjct: 384 GKLIWKITDYERKKREAMEGRAVSIFSQHFYTSWCGYRLCARAYLNGDGSGKGSFLSLYFVVMKGEFDSILLWPFKQKVTLMLLDQSGKKNHITDVFRAD--PNSSSFKRPDSEMNIASGCPRFASHAQLENPKNGCYIKDDTLFIKIVVDL 533
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Match: TRAF2 (TNF receptor associated factor 2 [Source:NCBI gene;Acc:100494415]) HSP 1 Score: 95.5153 bits (236), Expect = 3.610e-20 Identity = 50/147 (34.01%), Postives = 80/147 (54.42%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + F + R+DA +G+ +FS PFY+++ GYKM L +Y NG TG N +S++F ++KG +D L WP+ V L+DQ+ N V++ F D+ + RP +E ++ G F KL + DD I +V ++
Sbjct: 308 IWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDV--SSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVDL 451 HSP 2 Score: 93.5893 bits (231), Expect = 1.459e-19 Identity = 55/170 (32.35%), Postives = 87/170 (51.18%), Query Frame = 3
Query: 936 QLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
+LE + SE + + F W I F KR++A +G+ +FS PF +++ GY++ + NG G N +LS++ +MKG+ND L WPF VT +++Q +N H D+ +S + RP NI G P F +LE + + D+ I +K V L G
Sbjct: 290 ELETRMQESELS---TYDGVFIWKISEFGKKRQDAINGRCPAMFSPPFYTNKYGYKMCLRIYLNGDGTGRNTHLSLFFVVMKGNNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDV--SSSSFQRPISEMNIASGCPLFCQVSKLEGKNSYVRDDTIFVKVIVDLTG 453
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 110.153 bits (274), Expect = 8.887e-25 Identity = 82/365 (22.47%), Postives = 162/365 (44.38%), Query Frame = 3
Query: 426 LKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATK-------IPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
+ CP C I ++ EH+ +C + CPF + GC N+ +H + ++ H L+++ N + ++++ + ++ K + + + M + F + + ++ K + + I++ + +++ + V+ + +I ++QR+ EG + + H + KA++++NE W + ++ K+ A G +FS PF + GY+L +A NG G+ + +LS+Y +M+G D+ L WPF+ VT +++Q H + T+ PNS + RP NI G P F+S LE ++ I D+ + LK V L
Sbjct: 193 VSCPNRCVQT-IPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRG-NLLEHERAALQDHMLLVLEKNYQLEQRVNAL------LSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIH-KAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHI--VETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 546 HSP 2 Score: 92.8189 bits (229), Expect = 3.227e-19 Identity = 45/152 (29.61%), Postives = 79/152 (51.97%), Query Frame = 3
Query: 1473 GNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGL-IVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + +FS+PFY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ +V F D P+ + RP E ++ G +F+S L + I DD + +V ++
Sbjct: 397 SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKAD--PNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 546
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 110.153 bits (274), Expect = 8.887e-25 Identity = 82/365 (22.47%), Postives = 162/365 (44.38%), Query Frame = 3
Query: 426 LKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATK-------IPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
+ CP C I ++ EH+ +C + CPF + GC N+ +H + ++ H L+++ N + ++++ + ++ K + + + M + F + + ++ K + + I++ + +++ + V+ + +I ++QR+ EG + + H + KA++++NE W + ++ K+ A G +FS PF + GY+L +A NG G+ + +LS+Y +M+G D+ L WPF+ VT +++Q H + T+ PNS + RP NI G P F+S LE ++ I D+ + LK V L
Sbjct: 193 VSCPNRCVQT-IPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRG-NLLEHERAALQDHMLLVLEKNYQLEQRVNAL------LSSLERKKKMAAADSAIQHATNPMSRFQDIFSFLYRKALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIH-KAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHI--VETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 546 HSP 2 Score: 92.8189 bits (229), Expect = 3.227e-19 Identity = 45/152 (29.61%), Postives = 79/152 (51.97%), Query Frame = 3
Query: 1473 GNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGL-IVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + +FS+PFY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ +V F D P+ + RP E ++ G +F+S L + I DD + +V ++
Sbjct: 397 SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKAD--PNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 546
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 108.997 bits (271), Expect = 1.397e-24 Identity = 96/401 (23.94%), Postives = 160/401 (39.90%), Query Frame = 3
Query: 315 SEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLK-CP------ETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLM------QWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQ-----------NEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
+E+ CP S C+ C P +H + + CP + CG I ++H+R C+ R C F +GC E + N++ H L + H +LL+ Q + T N++ Q +I E K F + +LN + + + ++++ + K+E + NK+ QLE+ I + A++ Q F W I +F+ KR+ A +G+ IFS F + GY++ + NG G +LS++ +MKG ND L WPF VT +++ +N H D+ S + RP NI G P F ++E + + D+ I +K V L G
Sbjct: 152 TEQECPKRSLSCQH----------CRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQK------------------------IATFENIVCVLNREVERVAVTAEACSRQHRLD----QDKIEALSNKVQ----------QLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDV--TSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG 500 HSP 2 Score: 98.2117 bits (243), Expect = 4.997e-21 Identity = 48/147 (32.65%), Postives = 79/147 (53.74%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +FT+ R++A +G+ IFS FY+ R GYKM L +Y NG TG +S++F ++KGP+D L+WP+ V L+D H N V++ F D+ + RP ++ ++ G F K+ + DD I + ++
Sbjct: 355 IWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD-HNNREHVIDAFRPDVTSS--SFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf2 (TNF receptor-associated factor 2 [Source:MGI Symbol;Acc:MGI:101835]) HSP 1 Score: 108.227 bits (269), Expect = 2.335e-24 Identity = 96/401 (23.94%), Postives = 160/401 (39.90%), Query Frame = 3
Query: 315 SEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLK-CP------ETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLM------QWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQ-----------NEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
+E+ CP S C+ C P +H + + CP + CG I ++H+R C+ R C F +GC E + N++ H L + H +LL+ Q + T N++ Q +I E K F + +LN + + + ++++ + K+E + NK+ QLE+ I + A++ Q F W I +F+ KR+ A +G+ IFS F + GY++ + NG G +LS++ +MKG ND L WPF VT +++ +N H D+ S + RP NI G P F ++E + + D+ I +K V L G
Sbjct: 159 TEQECPKRSLSCQH----------CRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQK------------------------IATFENIVCVLNREVERVAVTAEACSRQHRLD----QDKIEALSNKVQ----------QLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDV--TSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG 507 HSP 2 Score: 98.2117 bits (243), Expect = 5.345e-21 Identity = 48/147 (32.65%), Postives = 79/147 (53.74%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +FT+ R++A +G+ IFS FY+ R GYKM L +Y NG TG +S++F ++KGP+D L+WP+ V L+D H N V++ F D+ + RP ++ ++ G F K+ + DD I + ++
Sbjct: 362 IWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD-HNNREHVIDAFRPDVTSS--SFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 505
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Match: Traf5 (TNF receptor-associated factor 5 [Source:MGI Symbol;Acc:MGI:107548]) HSP 1 Score: 92.8189 bits (229), Expect = 1.267e-20 Identity = 61/224 (27.23%), Postives = 108/224 (48.21%), Query Frame = 3
Query: 828 ILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
I++ + +++ + V+ + +I ++QR+ EG + + H + KA++++NE W + ++ K+ A G +FS PF + GY+L +A NG G+ + +LS+Y +M+G D+ L WPF+ VT +++Q H + T+ PNS + RP NI G P F+S LE ++ I D+ + LK V L
Sbjct: 24 IVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHINIH-KAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHI--VETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 244 HSP 2 Score: 90.5077 bits (223), Expect = 8.707e-20 Identity = 45/151 (29.80%), Postives = 79/151 (52.32%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGL-IVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + +FS+PFY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ +V F D P+ + RP E ++ G +F+S L + I DD + +V ++
Sbjct: 96 GKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKAD--PNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 244
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|O00463|TRAF5_HUMAN (TNF receptor-associated factor 5 OS=Homo sapiens OX=9606 GN=TRAF5 PE=1 SV=2) HSP 1 Score: 121.324 bits (303), Expect = 1.232e-27 Identity = 103/413 (24.94%), Postives = 190/413 (46.00%), Query Frame = 3
Query: 294 LKTYLNRSEKFCPGDSDYCKR--VLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNY-ATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQ--KSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
LK +L+ S +F YCK+ V+IN N+ + + CP C ++ +++EH+ +C + CPF + GC + N++QH S + H L+++ N + +I S++ + ++I+++ E I + + ++ F K FL VF ++ + ++ + +++ ++N+ + V+ + KI N+QR+ E + + H + KA++ +NE W + ++ K+ A G IFS F + GY+L +A NG G+ +LS+Y +M+G D+ L WPF+ VT +++Q K N++ T+ PNS + RP NI G P F++ LE + I D+ + LK V L
Sbjct: 153 LKEHLSASCQFRKEKCLYCKKDVVVINLQNH------EENLCPEYPVFCPNNCAKIILK-TEVDEHLAVCPEAEQDCPFKHYGCAVTD-KRRNLQQHEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFGKNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLENNDQRLAVLEEETNKHDTHIN-IHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNIME-----TFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551 HSP 2 Score: 86.2705 bits (212), Expect = 2.785e-16 Identity = 43/151 (28.48%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLS-MNPGLIVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + IFS+ FY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ + ++ F D P+ + RP E ++ G +F++ L I DD + +V ++
Sbjct: 404 GKLIWKVTDYKMKKREAVDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQ-SGKKNIMETFKPD--PNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKDDTLFLKVAVDL 551
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P70191|TRAF5_MOUSE (TNF receptor-associated factor 5 OS=Mus musculus OX=10090 GN=Traf5 PE=1 SV=1) HSP 1 Score: 113.62 bits (283), Expect = 4.232e-25 Identity = 86/365 (23.56%), Postives = 168/365 (46.03%), Query Frame = 3
Query: 426 LKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNY-ATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI-----NNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELE-TQTGLIVDNRIILKCKVHL 1439
+ CP C I ++ EH+ +C + CPF + GC N+ +H + ++ H L+++ N + I S++ + ++I+++ E + + + ++ F + FL T + + ++ + I++ + +++ + V+ + +I ++QR+ EG + + H + KA++++NE W + ++ K+ A G +FS PF + GY+L +A NG G+ + +LS+Y +M+G D+ L WPF+ VT +++Q H + T+ PNS + RP NI G P F+S LE ++ I D+ + LK V L
Sbjct: 193 VSCPNRCVQT-IPRARVNEHLTVCPEAEQDCPFKHYGCTVKGKRG-NLLEHERAALQDHMLLVLEKNYQLEQRISDLYQSLEQKESKIQQLAETVKKFEKELKQFTQMFGRNGTFLSNVQALTSHTDKSAWLEAQVRQLLQIVNQQPSRLDLRSLVDAVDSVKQRITQLEASDQRLVLLEGETSKHDAHIN-IHKAQLNKNEERFKQLEGACYSGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHI--VETFKADPNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 552 HSP 2 Score: 92.8189 bits (229), Expect = 2.075e-18 Identity = 45/152 (29.61%), Postives = 79/152 (51.97%), Query Frame = 3
Query: 1473 GNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGL-IVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + +FS+PFY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ +V F D P+ + RP E ++ G +F+S L + I DD + +V ++
Sbjct: 403 SGKLIWKVTDYRVKKREAVEGHTVSVFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKAD--PNSSSFKRPDGEMNIASGCPRFVSHSTLENSKNTYIKDDTLFLKVAVDL 552
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|P39429|TRAF2_MOUSE (TNF receptor-associated factor 2 OS=Mus musculus OX=10090 GN=Traf2 PE=1 SV=1) HSP 1 Score: 108.997 bits (271), Expect = 9.772e-24 Identity = 96/401 (23.94%), Postives = 160/401 (39.90%), Query Frame = 3
Query: 315 SEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLK-CP------ETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLM------QWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQ-----------NEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
+E+ CP S C+ C P +H + + CP + CG I ++H+R C+ R C F +GC E + N++ H L + H +LL+ Q + T N++ Q +I E K F + +LN + + + ++++ + K+E + NK+ QLE+ I + A++ Q F W I +F+ KR+ A +G+ IFS F + GY++ + NG G +LS++ +MKG ND L WPF VT +++ +N H D+ S + RP NI G P F ++E + + D+ I +K V L G
Sbjct: 152 TEQECPKRSLSCQH----------CRAPCSHVDLEVHYEVCPKFPLTCDGCGKKKIPRETFQDHVRACSKCRVLCRFHTVGCSEM-VETENLQDHELQRLREHLALLLSSFLEAQASPGTLNQVGPELLQRCQILEQK------------------------IATFENIVCVLNREVERVAVTAEACSRQHRLD----QDKIEALSNKVQ----------QLERSIGLKDLAMADLEQKVSELEVSTYDGVFIWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLDH-NNREHVIDAFRPDV--TSSSFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG 500 HSP 2 Score: 98.2117 bits (243), Expect = 3.495e-20 Identity = 48/147 (32.65%), Postives = 79/147 (53.74%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +FT+ R++A +G+ IFS FY+ R GYKM L +Y NG TG +S++F ++KGP+D L+WP+ V L+D H N V++ F D+ + RP ++ ++ G F K+ + DD I + ++
Sbjct: 355 IWKISDFTRKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRVYLNGDGTGRGTHLSLFFVVMKGPNDALLQWPFNQKVTLMLLD-HNNREHVIDAFRPDVTSS--SFQRPVSDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q12933|TRAF2_HUMAN (TNF receptor-associated factor 2 OS=Homo sapiens OX=9606 GN=TRAF2 PE=1 SV=2) HSP 1 Score: 105.145 bits (261), Expect = 1.892e-22 Identity = 84/356 (23.60%), Postives = 151/356 (42.42%), Query Frame = 3
Query: 390 DQPTNHRIA-RLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYAT-KIPIIRTILHNEE--NQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
D +H + + L C + CG I + ++H++ C R C F IGC E + ++H + + H ++L+ K + + +E+ + E + + + F + +LN ++ + + +Q I +KV+++ I + + LEQ++ E A + F W I +F+ KR+ A +G++ IFS F + GY++ + NG G +LS++ +MKG ND L WPF VT +++Q +N H D+ S + RP NI G P F ++E + + D+ I +K V L G
Sbjct: 174 DVKAHHEVCPKFPLTC-DGCGKKKIPREKFQDHVKTCGKCRVPCRFHAIGCLET-VEGEKQQEHEVQWLREHLAMLLSSVLEAKPLLGDQSHAGSELLQRCESLEKKT------------------ATFENIVCVLNREVERVAMTAEACSRQHRLDQDKIEALSSKVQQLERSIG---LKDLAMADLEQKVLEME---ASTYDGVFIWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQ-NNREHVIDAFRPDV--TSSSFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTG 500 HSP 2 Score: 93.2041 bits (230), Expect = 1.222e-18 Identity = 47/147 (31.97%), Postives = 77/147 (52.38%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +F + R++A +G+ IFS FY+ R GYKM L +Y NG TG +S++F ++KGP+D L WP+ V L+DQ+ N V++ F D+ + RP + ++ G F K+ + DD I + ++
Sbjct: 355 IWKISDFARKRQEAVAGRIPAIFSPAFYTSRYGYKMCLRIYLNGDGTGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQN-NREHVIDAFRPDVTSS--SFQRPVNDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDL 498
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Match: sp|Q6IWL4|TRAF6_DANRE (TNF receptor-associated factor 6 OS=Danio rerio OX=7955 GN=traf6 PE=1 SV=2) HSP 1 Score: 98.2117 bits (243), Expect = 3.588e-20 Identity = 102/485 (21.03%), Postives = 211/485 (43.51%), Query Frame = 3
Query: 174 RNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVL---NMKQHLLSEI----EVHSSLLMQWNENTKN------------EIDSIKNQV------NEIKE----------IKEKINRNSRRKLLSYFPK-QMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQIS------------IYEFKTKVEEIVNKI--NNQRINNY---------EGYQLEQEIHTSEKT----KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQAD-PNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNI-GVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
+ Y+ E + + +C IC + +A +PCG RFC C++ + + + CP D++ + + +F D I L +KC + +EL Q+E+H+ C CP CQE+ + + QH L I + S + +N + E++ I++Q+ + +K +EK+ RN + + F + M+++ FL LN T +P L +++ S + + V E+ ++ +Q+I + +L +++ + E++ +A+ +Q + W + NFS+ N ++G+ + S PF + GY+L + S + ++S+++ M+G D+ L WP + + ++++Q H + + T P+ + + RPT RN G G+ +F+ + L Q G + ++ ++++C+V
Sbjct: 55 QGYDVEFDPPLESKYECPICLMGLRSAVQTPCGHRFCDSCIRKSIRDTGQKCPVDNE------VLLEEQLFPDNFAKREILSLTVKCSNFGCSEKMELRQLEKHLSQCRFATAPCP----QCQESVPISHLDEHKSQHCLQRIMTCPDCAGSFVYAVKQNHEQFCPFANTVCEYCEMELIRDQLALHCDTDCLKAPVACTFSTFGCREKMTRNELAQHMQEFTQMHMRYMAEFL----RSQTLNNCT-MPSAAAHLSSDDRGASARSPDSCQCKQELLNLRETVLELEGRLVRQDQQIRELCIHNDTQKNQVTELRRKLVSLEESTRELEAQQYQGIYVWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETK---PDLQAFQRPTVMRNPKGFGYVTFLHLQALR-QRGFVKEDVLLVRCEV 520 HSP 2 Score: 62.3882 bits (150), Expect = 7.567e-9 Identity = 36/145 (24.83%), Postives = 70/145 (48.28%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTG-INEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSL-GFGFEKFISFEKLSMNPGLIVDDKIAFRV 1913
+W V+NF+ ++ ++G+ + + S PFY+ R GYK+ L L+ + + +S++ ++G D +L WP + + ++DQ + T PD RP ++ GFG+ F+ + L G + +D + R
Sbjct: 378 VWRVENFSHHLRNQEAGQPIVLHSPPFYTGRPGYKLCLRLHLQTPSAPRCSNFISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQVEGQHHIEVMETK---PDLQAFQRPTVMRNPKGFGYVTFLHLQALRQR-GFVKEDVLLVRC 518
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: T1E101 (TRAF-6 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 170.244 bits (430), Expect = 1.567e-42 Identity = 134/473 (28.33%), Postives = 228/473 (48.20%), Query Frame = 3
Query: 147 RFENVWRILRNYNFE-VNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEI----DSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIR----TILHNEENQI-----SIYEFKTKVE------EIVNK--INNQRIN-NYEGYQLEQEIHTSEKTKAEMHQN-------------EFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLY-----LSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLP-NSKEWNRPTQFRN-IGVGFPSFISFKELETQTGLIVDNRIILKCKVH 1436
+ +NV +L YN + V+ ++ DL C +C K+M +AC S CGC +C C++ YL+++ +CPGD CK +N + +VF + + RI+R+ +KCP + EL +++EH+ C + CP + IGC+E L+ M +HL ++ H+ L+M + K+EI ++ K ++ +KE+ ++ L QM+FL L M IL + I ++ T+L ++E+++ I F+ ++E E+V I NQ + E + ++ I ++ + + N +F W I +S KR V +++SD F SH + L NLY L ++ IMKG D+ L WP + VT SII Q S H + YD N K ++RP RN +G S + + ++ ++V++ II+ C VH
Sbjct: 5 KLDNVQELLSKYNVKRVDESVNNDLLCILCNKLMRDACESACGCHYCYTCIRIYLSQNHNYCPGDKTECKEDYLNLEGDVFRNIRLSTRISRIVVKCPNIRCNYTSELLRLKEHLDKCTPESVECPCVTIGCEEEPLLKDEMAKHLTDQVLRHTQLIMSFCNELKSEINHNNETTKEDISHLKEV-----LRVQKALNDEKTAQMEFLIEELRNKDNM-ILVLSQDIQEVKNEMITLLTSKESELKKLKSDIQIFRQEIEFMKNDLEVVGSTDIKNQVKDLKKEIFGIKMNIDSNNEERERKMNNLIRLNKLCPNVDMDFMWRIEEYSKKRRT-----VTDVYSDSFQSHNYKFCL-------------NLYIYGDNLGLWCVIMKGEKDDFLEWPMRRTVTLSIIEQDSLKTHKTTVFQYDTYQRNKKAFDRPKDERNDYCIGTDSLVRYSYIKETPMILVNDSIIVACVVH 453
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A2B4SJ65 (TNF receptor-associated factor 4 OS=Stylophora pistillata OX=50429 GN=Traf4 PE=4 SV=1) HSP 1 Score: 143.28 bits (360), Expect = 2.282e-33 Identity = 111/433 (25.64%), Postives = 191/433 (44.11%), Query Frame = 3
Query: 177 NYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTI------LHNEENQISIYEFKTKVEEIV-------NKINNQRINNY----EGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWN--RPTQFRNIGVGFPSFISFKELETQTGLIVDNRII 1418
Y+++ SEI D C IC + NA + CG RFC DCL + R+ CP D R ++ D +VF D+ + RI +KCP+ C Q +R ++ CP++ + C +N M ++L+ E H+++ QW + Q + K +PK + + F + N ++ + H E+ S F K ++ NK +++++ E L+ E K++M F W + F + AK G+ E+ SDPF + + GY+L +PNG G+ N +LS ++ +M+G +D L WPF VTF++++Q+ ++ + ++ + N+K N RPT N G G+ F+S ++L T+ L+ D I
Sbjct: 13 GYDYDFVSEIDEDFICQICHLPLRNAVLTRCGHRFCVDCLNEHFRRNSPNCPLD-----REKLDKDKDVFPDKASQRRILSYLIKCPDKC--------QWVGELRDVEGHKKKCPYVIVQCPNHN-CHERMARNLVEE---HAAVTCQWR--------MVSCQFCQKK-----------------YPKAEEHIHCETCHMFPLNCSNGCEQVVPREQVERRNLETHIHEDTTSHLGFACKKLAVLQQEFNKENKTLKKQLDDVKKENENLLLKASAQEKEMQKSKMETPTFVWKVTGFDDILRQAKHGRNNEMDSDPFYTGKYGYKLKLSVNPNGDGSGRNTHLSAFVIVMRGEHDGILPWPFNHKVTFTLVDQQESLDERENVVMH-FRANTKLENFARPTAEENPGRGYARFVSHEKLRTRRYLVDDTLFI 402 HSP 2 Score: 85.5001 bits (210), Expect = 6.115e-14 Identity = 48/146 (32.88%), Postives = 79/146 (54.11%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPA---VVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRV 1913
+W V F + + A+ G+ ++ S+PFY+ + GYK+ L + PNG +G N +S + +++G HD L WP+ V F L+DQ + VV F + + N RP E++ G G+ +F+S EKL +VDD + +V
Sbjct: 262 VWKVTGFDDILRQAKHGRNNEMDSDPFYTGKYGYKLKLSVNPNGDGSGRNTHLSAFVIVMRGEHDGILPWPFNHKVTFTLVDQQESLDERENVVMHFRANTKLE--NFARPTAEENPGRGYARFVSHEKLRTR-RYLVDDTLFIQV 404
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: I1ZID8 (TNF receptor associated factor-2 (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 135.191 bits (339), Expect = 1.310e-32 Identity = 64/177 (36.16%), Postives = 105/177 (59.32%), Query Frame = 3
Query: 153 ENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKE 683
E + R+L YNFEV + +LKC +CK +++NAC S CGCRFCS C+ Y++R +CPG + CK + +N+ D N +IA++R+KCPE + EL +EEH+R+C + + CPF +GC + +V+ ++ HL + HS L++ N +N+ + + E++E
Sbjct: 4 EKINRLLITYNFEVEGGVPDNLKCDLCKNLLVNACQSRCGCRFCSKCIMEYVSRGNLYCPGGTSECKEENLTICSNIHTDYRVNRKIAKMRVKCPEETCKVYCELVDIEEHLRLCTMKSQNCPFFVLGCNQPKMVIQDLTNHLQNGTFQHSKLIIDIISNMRNDFFGLTTKEVELRE 180
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A3M6TEQ9 (Uncharacterized protein (Fragment) OS=Pocillopora damicornis OX=46731 GN=pdam_00013439 PE=4 SV=1) HSP 1 Score: 138.658 bits (348), Expect = 1.935e-31 Identity = 118/441 (26.76%), Postives = 205/441 (46.49%), Query Frame = 3
Query: 177 NYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKF-CPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWN--------ENTKNEIDSIKNQVNEIKEIK-----EKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVN-------KINNQRINNY--EGYQLEQEIHTSEKT--KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWN--RPTQFRNIGVGFPSFISFKELETQTGLIVDNRII 1418
Y+++ +E+ D C IC+ + NA + CG RFC DCL + R + CP D R ++ D ++F D+ + RI +KCP C Q E +R N ++ CP+ + C +N V + ++L IE H ++ QW E + I N+ + + E++ R ++L + + + T + F+ L N + + T H E+ + F K ++ K +++++ E L ++ EK K++M F W I F + AK G+ +I SDPF + + GY+L +PNG G+ N +LS ++ +M+G +D L WPF VTF++I+Q+ ++ ++ +T N+K N RPT N G G+ F+S ++L+T+ L+ D I
Sbjct: 21 GYDYDFVTELDEDFVCQICQLPLRNAVLTRCGHRFCHDCLNEHFKRIQHPNCPLD-----RTRLDKDKDIFPDKASERRILSYFVKCPNRC--------QWEGELRDVENHQQICPYEVVQCPSSNCRVF-LARNL---IEEHVAVSCQWRIVSCQFCPEKYPKAEEDIHNETCPMFPLNCSNGCEQVV--PREQMLKHLETECRL--TPVSCPFHDLGCNMKVERRNLET--HVREDTTTHLSFACKKLALLQQEFDEEKKTLKKQLDDLKKENNNLLLKVSAQEKEMHKSQMETPMFVWKITGFGDILHQAKVGRNNKIDSDPFYTGKYGYKLKLSVNPNGDGSGRNTHLSAFVIVMRGEHDAILPWPFNQKVTFTLIDQQESL-DERQNVTMLFRANTKLENFARPTAEENPGRGYARFMSHEKLKTRRYLVDDTLFI 437 HSP 2 Score: 81.2629 bits (199), Expect = 1.787e-12 Identity = 47/146 (32.19%), Postives = 77/146 (52.74%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPA---VVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRV 1913
+W + F + A+ G+ +I S+PFY+ + GYK+ L + PNG +G N +S + +++G HD L WP+ V F L+DQ + V F + + N RP E++ G G+ +F+S EKL +VDD + +V
Sbjct: 297 VWKITGFGDILHQAKVGRNNKIDSDPFYTGKYGYKLKLSVNPNGDGSGRNTHLSAFVIVMRGEHDAILPWPFNQKVTFTLIDQQESLDERQNVTMLFRANTKLE--NFARPTAEENPGRGYARFMSHEKLKTR-RYLVDDTLFIQV 439
BLAST of TNF receptor-associated factor vs. TrEMBL
Match: A0A485MBY1 (TNF receptor-associated factor OS=Lynx pardinus OX=191816 GN=LYPA_23C013043 PE=3 SV=1) HSP 1 Score: 134.806 bits (338), Expect = 7.634e-30 Identity = 118/463 (25.49%), Postives = 212/463 (45.79%), Query Frame = 3
Query: 219 KCTICKKIMINACNSPCGCRFCSDCLKTY--LNRSEKFCPGDSDY-----------CKRVLINFDNNVFC-DQPT-NHRIARLRLK------CPE---TCGDDFIEL---NQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEID----SIKNQVNEIKEIKEKINRNSR--RKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEI--------VNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNE--------------FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELET-QTGLIVDNRIILKCKVHL 1439
KC C ++ N + CG RFC C+ + LN + CP D + CKR ++N V+C + P+ N +I R + CPE +C + +++ ++++EH+ +C + CPF + GC + N+ +H S + H L+++ N + +I S++ + ++I+++ E + + + ++ K FL + LI A +R +L Q + ++ + VE I + + N+QR+ EG + + H + KA++++NE W + ++ K+ A G IFS PF + GY+L +A NG G+ + +LS+Y +M+G D+ L WPF+ VT +++Q H + T+ PNS + RP NI G P F++ LE+ + I D+ + LK V L
Sbjct: 44 KCAFCHSVLHNPHQTGCGHRFCQHCILSLRELN-AVPLCPVDKEVIKSQEVFKDNCCKREVLNL--YVYCKNAPSCNAKIILGRYQNHEENLCPEYPVSCPNKCLQMIPRSEVDEHLAVCPEAEQDCPFKHYGCTVKDKRG-NLLEHEHSALRDHMLLVLEKNFQLEEQISDLYKSLEQKESKIQQLAETVKKFEKEFKQFAQLLGKNGSFLSN--IQALASLIDKSAWLEAQVRQLLQVANQQQNKFDLRPLVEAIDTVKQKITLLETNDQRLVVLEGETNKHDAHIN-IHKAQLNKNEERFKLLEGACYNGKLIWKVTDYKTKKREALDGHTVSIFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHI--METFKADPNSSSFKRPDGEMNIASGCPRFVAHSTLESAKNTYIKDDTVFLKVAVDL 497 HSP 2 Score: 93.2041 bits (230), Expect = 4.000e-16 Identity = 45/151 (29.80%), Postives = 79/151 (52.32%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKL-SMNPGLIVDDKIAFRVTTEV 1925
K+IW V ++ +++A G + IFS+PFY+ R GY++ Y NG +G +S+YF +++G D L+WP++ V L+DQ ++ F D P+ + RP E ++ G +F++ L S I DD + +V ++
Sbjct: 349 GKLIWKVTDYKTKKREALDGHTVSIFSQPFYTSRCGYRLCARAYLNGDGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIMETFKAD--PNSSSFKRPDGEMNIASGCPRFVAHSTLESAKNTYIKDDTVFLKVAVDL 497
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf5 (TNF receptor-associated factor 5 [Source:NCBI gene;Acc:103031120]) HSP 1 Score: 104.375 bits (259), Expect = 4.710e-23 Identity = 82/367 (22.34%), Postives = 166/367 (45.23%), Query Frame = 3
Query: 426 LKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKN----QVNEIKE-------IKEKINR------------NSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKI--NNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELET--QTGLIVDNRIILKCKVHLDG 1445
++CP C ++ +++++H C Q C + GC N +K H +E H LL++ N ++D ++ Q E+KE +K ++++ +R+L+S +++K L+ L ++ +R L + Q+++ + + + + ++ R+ + QL+ ++ ++ + + W +H++ K+E + + S PF + +GY+L + G G +LS+Y+ +M+G D+ L WPF+ NVT ++++Q N H T D+ N+ + RPT N +GFP FI+ +LE + D+ + +K KV G
Sbjct: 195 VQCPNKC-IHLVKRHKLKDHADECPEQETDCIYKKYGCTVRNKRG-QVKVHEQTEFNHHVLLLLESNSKLIKQVDQLQQDFAAQQGELKERNLLVSNLKREVSKCDTTVSAMQRSVEEQRELVSSVKRELKDLRDVLEADLT------KEELVSLRASLDSLREQVAMTQSLREHLGALGQTCQSHTRLLDIHVQQLQCSEQRFQQLESTSYDGKLIWKVHDYHRKKEAGTA-----LNSPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVSLSFTPDLASNN--FRRPTSETNAALGFPRFITHADLEAPRNAAYVRDDTLFIKVKVDTTG 546 HSP 2 Score: 84.7297 bits (208), Expect = 9.507e-17 Identity = 47/152 (30.92%), Postives = 75/152 (49.34%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSM--NPGLIVDDKIAFRVTTEV 1925
K+IW V ++ + ++G AL S PFY+ +GYK+ +Y G T +S+Y +++G D L WP++ NV ++DQ N V FT DL + N RP +E + GF +FI+ L N + DD + +V +
Sbjct: 400 GKLIWKVHDY---HRKKEAGTALN--SPPFYTSHSGYKLSARVYLGGEGTARGTHLSLYVMLMRGDFDSLLPWPFRQNVTLAVLDQSGNRNHVSLSFTPDLASN--NFRRPTSETNAALGFPRFITHADLEAPRNAAYVRDDTLFIKVKVDT 544
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf2b (TNF receptor associated factor 2 [Source:NCBI gene;Acc:103028261]) HSP 1 Score: 102.834 bits (255), Expect = 1.190e-22 Identity = 93/394 (23.60%), Postives = 160/394 (40.61%), Query Frame = 3
Query: 318 EKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIA-RLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQH----------------LLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINN-QRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
E+ C + CK + F F D + I + ++C + CG I + EH + C + C F IGC+ VV N KQH +LS + V S +W E++ + + E ++M L+ + +LN + ++R + Q+ + K+E + NK+ +R QL + + + + F W I +FS +R++A +G+ +FS F S + GY++ + NG G +LS++ +M+G D L WPF VT +++Q +N H D+ +S + RP NI G P F +L ++ + D+ I +K V L G
Sbjct: 161 ERECEARTLNCKYCKVTFS---FKDIKAHDEICQKFPMQCKD-CGKKKIPREKFAEHSKSCAKSKSACQFSEIGCRA---VVDNGKQHEHEQSSIIEHLRLMLAVLSTVRVRSDGPGEWQEDSGLGL----YRGPEDAAPPGAHAAAHNAAGGPGVQQKMTALENIVC------VLNREVERTVLRLEALTRQQQLD----QEKIENLSNKVRQLERTLTMRDLQLAESEQALRELQFCTYDGVFVWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQ-NNREHIIDAFRPDI--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDLTG 530 HSP 2 Score: 98.2117 bits (243), Expect = 3.724e-21 Identity = 47/147 (31.97%), Postives = 81/147 (55.10%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
+W + +F++ R+DA +G+A +FS FYS + GYKM L LY NG TG +S++F +++G +D L+WP+ V L+DQ+ N +++ F D+ + RP +E ++ G F KL+ + DD I + ++
Sbjct: 385 VWKISDFSRRRQDALAGRAPAMFSPAFYSSKYGYKMCLRLYLNGDGTGRGSHLSLFFVVMRGKYDALLKWPFSQKVTLMLLDQN-NREHIIDAFRPDI--SSTSFQRPISEMNIASGCPLFCPLAKLAGKSSYLRDDTIFIKAIVDL 528
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:103024022]) HSP 1 Score: 101.293 bits (251), Expect = 3.236e-22 Identity = 59/164 (35.98%), Postives = 89/164 (54.27%), Query Frame = 3
Query: 984 HQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
H W ++++S K + AK +E FS PF +H GY+L A NG+G+ E +LSIYI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P+ RN +G G+P FIS E+ + I DN I LK + + K+
Sbjct: 306 HDGVLIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKRN-YIRDNAIFLKASIEIPQKI 468 HSP 2 Score: 89.3521 bits (220), Expect = 2.363e-18 Identity = 48/159 (30.19%), Postives = 86/159 (54.09%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +SIY +++ G +D+ LEWP+ V F ++DQ + T+ PD P+ +R E +LGFG+ KFIS +++ I D+ I + + E+ +K
Sbjct: 310 LIWKLNDYSRKLQEAKLHNNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSIYIRVLPGEYDNLLEWPFAYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPSSSRNSLDESTLGFGYPKFISHDEIRKR-NYIRDNAIFLKASIEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 94.7449 bits (234), Expect = 4.374e-20 Identity = 100/460 (21.74%), Postives = 202/460 (43.91%), Query Frame = 3
Query: 174 RNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNEN---------TKNEIDSIKNQVN---EIKEIKEKINRNSRRKLLSYFPK-QMKFLKTFLV-FTFYMLILNY------------ATKIPIIRTILHNEENQI--SIYEFKTKVEEIVNKINNQRINN----YEGYQLEQEIHTSEKT----KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQ---ADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNI-GVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
+ Y+ + + + +C IC + +A +PCG RFC+ C++ + + + CP D++ + ++ +F D I L ++C + +EL +E HI C CP CQE+ + +++H+ E EN + + D +K V I +EK+ RN + F + M+++ L T LI ++ A+ P + E Q+ ++ E ++++ +K+ I N + +L +++ + E++ +A+ +Q + W + FS N ++G + S PF + GY+L + PN Y+S+++ M+G D+ L WP + + ++++Q H + + T P+ + + RPT RN G G+ +F+ + L Q G + D+ ++++C+V
Sbjct: 54 QGYDVDFDPPLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNE------VLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCP----QCQES-VWKSELEEHINQECSHRLITCPDCAENIIYAEKQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSN--YISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETK---PDLQAFQRPTVQRNPKGFGYVTFMQLQALH-QRGFVRDDVLMVRCEV 496 HSP 2 Score: 63.929 bits (154), Expect = 2.733e-10 Identity = 37/144 (25.69%), Postives = 69/144 (47.92%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTG-INEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSL-GFGFEKFISFEKLSMNPGLIVDDKIAFR 1910
+W ++ F+ ++ ++G + + S PFY+ R GYK+ L L+ N + +S++ ++G D +L WP + + ++DQ V T PD RP +++ GFG+ F+ + L G + DD + R
Sbjct: 354 VWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETK---PDLQAFQRPTVQRNPKGFGYVTFMQLQALHQR-GFVRDDVLMVR 493
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Match: traf6 (TNF receptor associated factor 6 [Source:NCBI gene;Acc:103021325]) HSP 1 Score: 93.9745 bits (232), Expect = 9.637e-20 Identity = 102/479 (21.29%), Postives = 208/479 (43.42%), Query Frame = 3
Query: 174 RNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCP-------------FINIGCQENNLVVLNMKQHLL-SEIEVHSSLLMQWN--------ENTKNEI------DSIKNQVN---EIKEIKEKINRNSRRKLLSYFPK-QMKFLKTFLV-FTFYMLILNY------------ATKIPIIRTILHNEENQI--SIYEFKTKVEEIVNKINNQRINN----YEGYQLEQEIHTSEKT----KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQ---ADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNI-GVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
+ Y+ + + + +C IC + +A +PCG RFC+ C++ + + + CP D++ + ++ +F D I L ++C + +EL +E HI C CP IN C + + ++++ +E + H L + N E +N++ D +K V I +EK+ RN + F + M+++ L T LI ++ A+ P + E Q+ ++ E ++++ +K+ I N + +L +++ + E++ +A+ +Q + W + FS N ++G + S PF + GY+L + PN Y+S+++ M+G D+ L WP + + ++++Q H + + T P+ + + RPT RN G G+ +F+ + L Q G + D+ ++++C+V
Sbjct: 54 QGYDVDFDPPLESKYECPICLMGLRSAVQTPCGHRFCNCCIRKSIRDTGQKCPVDNE------VLTEDQLFPDNFAKREILSLTVRCRNVGCMEKMELRHLENHIPHCKFATVPCPQCQESVWKSELEEHINQECSHRLITCPDCAENIIYAEKQFHEQLCLFANTVCEYCNMELIRNQLASHCDTDCLKAPVACTFSIFGCREKMLRNDLALHMQEFTQMHMRYMADVLRNQTINGLISSHSASAASPTDSRGASSRPEGACQCNQELQQMRETVLELESRLVRQDHKLRELSIRNETQSTQMTELRKKLASLEESMRELQAQQYQGVYVWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSN--YISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETK---PDLQAFQRPTVQRNPKGFGYVTFMQLQALH-QRGFVRDDVLMVRCEV 520 HSP 2 Score: 64.3142 bits (155), Expect = 2.065e-10 Identity = 37/145 (25.52%), Postives = 69/145 (47.59%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTG-INEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSL-GFGFEKFISFEKLSMNPGLIVDDKIAFRV 1913
+W ++ F+ ++ ++G + + S PFY+ R GYK+ L L+ N + +S++ ++G D +L WP + + ++DQ V T PD RP +++ GFG+ F+ + L G + DD + R
Sbjct: 378 VWRLEGFSTHIRNQEAGHPVVLHSPPFYTGRPGYKLCLRLHLQTPNAPRCSNYISLFVHTMQGEFDSQLSWPLQGTIRLAVLDQAEGQHHVEVMETK---PDLQAFQRPTVQRNPKGFGYVTFMQLQALHQR-GFVRDDVLMVRC 518
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 114.775 bits (286), Expect = 1.319e-27 Identity = 86/395 (21.77%), Postives = 168/395 (42.53%), Query Frame = 3
Query: 300 TYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRR--KLLSYFPKQMKFLKTFLVFTFYMLI--------LNYATKIP-------IIRTILHNEENQISIYEFK----TKVEEIVNKINNQRINNYEGYQLEQEIHTSEKT----KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDN 1409
T L CP +++CK ++ ++ A+ L CP C + I ++ +H+ C + C F +GC ++++H S + H +L++ N + + ++ + + + E + + + + LS++ T L T ML L+ A + P +R + ++ E EE + ++ QR+ ++G + T+E+ + + + W I +++ +++ A SG+ ++S PF + GY++ +A NG G +LS++ +M+G D L WPF+ VT S+++Q + H T D P S + RP N+ G P F+S LE + L+ D
Sbjct: 20 TRLAAHRASCPHRAEFCKYCSAAVTCSLL-ERHHKEECAQYPLPCPNNCEEHGIPRAELSQHMSACAMSTKLCGFHMLGCTFKQGTSESVREHEESAVRSHFTLVISRNSELELQCARLQCSIEDHTNMSEMLTQRVAQLEQDLSHWSTLTGSNNTRLGSTLEMLTQHNEQLQSLHVAQRAPQRDADTAALRRDMATLRERLRALEAALGNPGPCEERCH-MHEQRLTMHDGL-----LDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPD--PASGSFRRPDGDMNVASGCPLFVSHVALEGSSYLVDDT 405 HSP 2 Score: 97.0561 bits (240), Expect = 9.007e-22 Identity = 45/149 (30.20%), Postives = 80/149 (53.69%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTE 1922
K++W ++++ + +++A SG+ L ++S+PFY+ GYKM Y NG G +S++F +++G +D LEWP++ V L+DQ + + FT D P + RP + ++ G F+S L +VDD + RV +
Sbjct: 268 GKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLDQGAARRHLSDTFTPD--PASGSFRRPDGDMNVASGCPLFVSHVALE-GSSYLVDDTVFVRVVVD 413
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 102.834 bits (255), Expect = 2.120e-23 Identity = 84/377 (22.28%), Postives = 165/377 (43.77%), Query Frame = 3
Query: 408 RIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSR---RKLLSYFPKQMK-------FLKTFLVFTFYMLILNYATKIPIIRTILHN------EENQISIYEFKTKVEEI-------VNKINNQRINNYEGY--QLEQEIHTSEKTKAEM-----------HQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILK 1424
R R + CP C + I ++ H+ IC ++ C F GC+ + +K+H + H SL+ + N + ++ +++Q+ E + + R ++L+S K + V T +L L + + R H+ + +++E T+V I + R+ + + + ++ + AEM + + W I +++ ++++A SG+ ++S PF + GY++ +A NG G +LS++ +M+G D L WPF+ VT ++++Q + ++R L T+ P S + RPT NI G P F+S LE+ + + D+ I +K
Sbjct: 97 RCPRYPIPCPNKCEEQSIAREELVSHLGICPYKQAECFFSQFGCKYKG-TLQGLKEHESGATQQHLSLVTARSANLELKVSMLQSQLAERANSADLLGTRVRELEKELISVGQTASKNESVLCVVQRMLAVQTERLLRLQESMQ-GTTRRADHDALRGDLDGTAATLHELGTRVAAIEESGGSVTHSSTPTRLAALDSALSRHDTQLFAHDTRLAEMDLRFQVLETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGA----ARRQLSDTFKPDPASSSFRRPTSDMNIASGCPLFVSHVALESAS-YLQDDTIFIK 466 HSP 2 Score: 92.0485 bits (227), Expect = 6.389e-20 Identity = 42/150 (28.00%), Postives = 79/150 (52.67%), Query Frame = 3
Query: 1476 NKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
K++W ++++ + ++DA SG+ L ++S+PFY+ GY+M Y NG G +S++F +++G +D L WP++ V L+DQ + + F D P + RP ++ ++ G F+S L + + DD I +V +
Sbjct: 325 GKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNGDGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLDQGAARRQLSDTFKPD--PASSSFRRPTSDMNIASGCPLFVSHVALE-SASYLQDDTIFIKVVVDT 471
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Match: traf6 (TNF receptor-associated factor 6 [Source:NCBI gene;Acc:554561]) HSP 1 Score: 60.4622 bits (145), Expect = 8.483e-10 Identity = 72/362 (19.89%), Postives = 152/362 (41.99%), Query Frame = 3
Query: 444 CGDDFIELNQMEEHIRI-CNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKF-LKTFLVF----TFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTS-EKTKAEMHQNEFTWTIHNFSNKRENA-KSGKVYE---------IFSDPFLSHENGYQLMFQAD-------PNGSGNYENL------YLSIYICIMKGSNDNNLLWPFKLNVTFSIINQ-KSNMVHSKRLLTYDMLPNSKEWNRPTQFRNI-GVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
C + I Q+ H+ + C + C F +GC E +V + H+ +VH LL N + ++ QV + + ++ LS+ ++T + + A ++ +R I E ++ + + + E+ K +NQ+ E +L + + ++++ + FTW + FS SG + + S F + GY+L + P G+ + L +L++++ +++G D+ L WPFK + S+++Q + + VH ++ D P + RP+ RN G G+ +F+ L ++ + D+ ++++C+V
Sbjct: 215 CQQELIR-EQLGPHLEVDCQQAQVPCTFSPLGC-EAQMVRSLLAAHMHEHTQVHMRLL-------ANGLKILRIQVGQGAQPSSAAGSSAPPNSLSWLSSTSGGDVQTAGASRSQGSRDRAACDCAQELDRLREITRTLEERVVLQLHQ--IRELSAKTDNQQGLLAEATRLVRSLEARVAESESRLCAGIFTWRVERFSRLLPGGLASGFASDGMHPDAPAVMHSSGFYTGVPGYRLCLRLQVLSGREVPAGAASPSVLLAGRQPHLALFVHLLQGDYDHRLPWPFKGRIRISVVDQCERDSVHVTEMMDAD--PQLSAFQRPSVHRNPKGFGYMNFMDINTLHHRS-YLRDDCLVVRCEV 562
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27]) HSP 1 Score: 112.849 bits (281), Expect = 2.334e-26 Identity = 107/421 (25.42%), Postives = 179/421 (42.52%), Query Frame = 3
Query: 327 CPGDSDYCKRVLINFD--------------NNVFC--DQPTNHRIARLR------LKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVN------------------EIKEIKEKIN-RNSRRKLLSYFPKQMK--FLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTK------------AEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILK 1424
C SD C +++ F V+C D P I L+ ++CP CG IE ++ H R C N C F +GC + + +++H + H LL + + + ++NQ+ E ++KE+ N +N+R ++ K + ++ F L+ + + + + + N+ + ++E + N N QLE I T KTK A + F W I F+ + AKSG I+S PF +H GY+L + PNG G+ + YLSI+I +M+G D+ L WPF+ +T ++I+Q + M S+ T+D P S + RPT+ N+ G P F S L T+ G + +N + +K
Sbjct: 106 CIHASDGCGEIMLRFQLAKHVEKECPFRLITCVYCQNDVPERTLIEHLKKCPAFPIECPNECGVKRIERKKLSAHTRECPNALTDCRFSPLGCT-YKVKKIALREHQNKHVIKHMILLGRTTGEPQPNLLELENQLERFDGENTSFKTELERHKYEFAQMKERFNDQNARLGIVEKTVANQKGDIAEIWMRFDQENLVGEVRMRDKLKKFKVKTKANKECLLSLMKRLEVQDDSQTNPNKLNRRLSQLESSI-TIHKTKLFQEDLRIQIQQAISYDGTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNGMNISE---TFDPDPCSISFQRPTRNINVASGCPRFCSQTVLRTR-GYMNENCVFVK 520 HSP 2 Score: 81.6481 bits (200), Expect = 2.833e-16 Identity = 40/123 (32.52%), Postives = 66/123 (53.66%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFIS 1853
+W + FT+ +A+SG A I+S PFY+HR GYK+ L+PNG + + +SI+ +++G +D L WP++ + L+DQ N + F D P + RP ++ G +F S
Sbjct: 383 LWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQ-DNGMNISETFDPD--PCSISFQRPTRNINVASGCPRFCS 502
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO41243 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4Z7]) HSP 1 Score: 99.3673 bits (246), Expect = 4.982e-22 Identity = 112/473 (23.68%), Postives = 200/473 (42.28%), Query Frame = 3
Query: 177 NYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNR-SEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLIL-----------------NYATKIPII----------RTILHN---EENQISIY-----EFKTKVEEIVNKINNQRINNYEGYQLEQ---EIHTSEKTKAEMHQ--------NE-----FTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNS--KEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
Y+ E ++ + C IC + + CG RFC +CL R S CP D R ++ +VF D+ I +KCP EL +E H R C+ + C N C L +++ +HLL E + + + + + Q + K+ S + P+ M + LV + LI+ N K P++ R L + EE Q ++ +F +V EI N++ +Q ++ L ++ S + A+ H+ NE F W I +F++ AK G + S+PF + +NGY+L PNG+ + +N ++S ++ I +G D L WPF + ++++QK N++ +R + ++PN + ++RP N G G +F+S ++L T+ +VD + ++ +V
Sbjct: 10 GYDSEFVIAVAEEYTCRICHLPLRVPVQTKCGHRFCKECLDEASRRKSRAECPMD-----REPLDLKKDVFLDKAAERTILSFLVKCPCKGCKWEAELRDLEAHARNCDYELVTCS--NPMCSA-QLPRMDVDEHLLVECDWRLIVCEYCGDESPYCL-----QKAHARNCDYKLVTCSNPMCSAQLPR-MDVDEHLLVECDWRLIVCEYCGDESPYCLQKDHSNQCDKFPVLCPNDCGTQITREKLRDHQSEECQFAVVPCAFRDFGCEV-EIQNRLMDQHLDTNIQSHLNMTCNQLLLSRDSGAQFHELQQGLGRVNELLKMRFVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQKENVLQ-RRNVEKTIIPNPSLENFHRPKTVSNNGRGSATFVSHEKLWTEN-YVVDGTLFMQVEV 465 HSP 2 Score: 79.337 bits (194), Expect = 1.098e-15 Identity = 43/131 (32.82%), Postives = 70/131 (53.44%), Query Frame = 3
Query: 1479 KIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHP--NRNRPFTEKSLGFGFEKFISFEKL 1865
+ +W + +F + A+ G +++ SEPF++ +NGYK+ LYPNG +G N +S + I +G +D L WP+ + L+DQ N N ++P+ N +RP T + G G F+S EKL
Sbjct: 319 RFVWRIPDFADSLRQAKLGLKVRLDSEPFFTEKNGYKLRATLYPNGTMSGKNTHISAFVSINRGEYDGILAWPFTRVIKITLLDQKENVLQRRN-VEKTIIPNPSLENFHRPKTVSNNGRGSATFVSHEKL 448
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36]) HSP 1 Score: 94.7449 bits (234), Expect = 2.100e-20 Identity = 92/411 (22.38%), Postives = 171/411 (41.61%), Query Frame = 3
Query: 294 LKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEH-IRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRN--SRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINN-----------------QRINNYEGYQLE-QEIHTSEKT------KAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
L+ +L R E F P D YC + + H + CP CG + I +++ H IC C F GC ++ H + VH +LL+ +N + + +++++++ + K +R+ L+ + ++ + L + ++ ++ + +E + +I E ++ I N+ + +R + +QL +I +E +A + + W I ++ + + SGK I+S PF GY+ + PNG G + +LS++ +M+G D L WPF+ VTF +++Q + VH T+ P S + RPT NI G P FIS L+T+ + D+ + +K V G
Sbjct: 128 LEAHLERCE-FKPSDCQYCLQRIPAASMEDHLQTCEKHPVV-----CPH-CGAEGICRDELLHHQTNICEQAELPCSFAKHGCHFKG-TREALETHFRDQASVHVNLLLTATQNEEKARSEMAAKLSQMEKERAKQQEQMYEQREALAVANQNLRTYQGKL-NVIERSVAEQRRELAELKERIQLQEVEAAIREQDRRLGMIENEASRGAAPSSGPGSMGGTMALERRQDRNEHQLALHDIQLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQ--DRVHDIG-DTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTRA-YVRDDTMFIKIAVDTTG 525 HSP 2 Score: 84.3445 bits (207), Expect = 4.041e-17 Identity = 45/149 (30.20%), Postives = 73/149 (48.99%), Query Frame = 3
Query: 1485 IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRN--RPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
IW + +T+ ++ SGK I+S PFY R GYK +YPNG G +S++F +++G D L WP++ V F+L+DQ V+ D PD + + RP + ++ G FIS L + DD + ++ +
Sbjct: 381 IWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLDQDR-----VHDIGDTFRPDPTSSSFKRPTSNMNIASGCPLFISHTNLQTR-AYVRDDTMFIKIAVDT 523
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4]) HSP 1 Score: 94.3597 bits (233), Expect = 2.243e-20 Identity = 106/466 (22.75%), Postives = 189/466 (40.56%), Query Frame = 3
Query: 231 CKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKC---PETCGDDFIELNQMEEHIRICNNQRRFCPFINIG---------------CQ---------ENNLVVLNMKQHL-----------------LSEIEVHSSLL-----MQWNENTKNEIDSIKNQVNEIKEIKEK-------------INRNSRRKLLSYFPKQMKFLKT------FLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILK 1424
C+ I+ +A + CG R+CS C+ L+R P D C + + F D+ + I L + C P C + EL + H C C G CQ E +VV MK+H L +EVHS+ ++ +N ++ +++ + IK+++++ I+ N + + +++ ++ LV + + ++ + L ++ I E + ++ + + N I + LE+ ++T + T + + W I N +NKR A SG+V +S F + +GY++ + NG G N ++S++ IM+G D L WPF+ VT +++Q N+ H D P+S + RP NI G P F S ++L TQ I D+ + LK
Sbjct: 27 CRLIVKDAVQTACGHRYCSPCISPLLSRG----PIQCDVCGSTITKPET--FRDKFADREILELHVHCVNQPHGCPWEG-ELRHRQNHHTKCEFNPISCVHPECGKKLSVAKLPEHLQNECQYREETCSYCEQPVVVARMKEHHEKTCPSYPVNCPKCSKELIRVEVHSTPFTREPRLEKGRGCENTLEVLEDHESRIKKLEQRGGGIGVNGLQSMRISENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLAIAD-----LEERLNTLQGTTFD---SVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQ-DNVEHVIDAFRPD--PSSSSFQRPRAEMNIASGCPLFCSHEQL-TQHAYIRDDTMFLK 473 HSP 2 Score: 85.5001 bits (210), Expect = 1.259e-17 Identity = 46/147 (31.29%), Postives = 75/147 (51.02%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTE 1922
++W + N R +A SG+ +S F++ +GYKM +Y NG G N VS++F I++G D L WP++ V L+DQ N V++ F D P + RP E ++ G F S E+L+ + I DD + ++ +
Sbjct: 335 LLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQ-DNVEHVIDAFRPD--PSSSSFQRPRAEMNIASGCPLFCSHEQLTQH-AYIRDDTMFLKIIVD 477
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91]) HSP 1 Score: 93.5893 bits (231), Expect = 3.838e-20 Identity = 108/465 (23.23%), Postives = 197/465 (42.37%), Query Frame = 3
Query: 126 PSSMESI-RFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCP--------------FINIGCQENNLVVLNMKQHL-LSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKI-NRN---------SRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDML--PNSKEWNRPTQFRN-IGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
P+S+ I ++ R+ Y+ + + +C IC + + +PCG RFC +C++ + + CP D+ + DN F + I RLK C L ++EEH++ C CP C ++ + K + +S+IE H + N NE ++ + K E NR+ S ++ S+ P++ + L N ++ ++ + +E Q Y + KVE+ V +++RI + E E + + F W + NF RE + +G I S PF + GY++ + + NG ++S++I +M+G D L WPF +T SI++Q S+ + S+R ++ ++ PN + RPT RN G G+ F +L T+ I +N I+++ ++
Sbjct: 25 PASLPFINQYGGPQRLEEGYDEFFDPPLESKYECPICLLGLRDPVQTPCGHRFCFNCIRRSIRDAGPKCPVDNTPLSERELYRDN--FAKREMMSFIVWCRLKKERGCTWKGA-LKELEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKVTISKIEEHLKGCPCMDTNCPNECGAVMQRKEVDKHCAEACPNRSVPCDHCKMKSSKEQASHGPQEHTPHEAELRREALFQSANMQREVDMLGS-RGDEYRQFLAY-LERKVED-VKTSSDRRIAELTHKLMRLETREIE-LEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQ-SDQIDSRRPISETLVAKPNLLAFQRPTSPRNHKGYGYVEFCPIDQL-TEGQYIKNNSILVRIQI 480 HSP 2 Score: 78.9518 bits (193), Expect = 1.626e-15 Identity = 43/151 (28.48%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1428 KVHLDGKLANTLHENGNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNR---NRPFTEKS-LGFGFEKFISFEKLS 1868
++ L+G++ N IW + NF Q R+ + +G I S PFY+ GYKM L + NG++ G+ E VS++ +++G D LEWP+ + ++DQ + + + L PN RP + ++ G+G+ +F ++L+
Sbjct: 322 EIELEGRVCN------GTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILDQSDQIDS--RRPISETLVAKPNLLAFQRPTSPRNHKGYGYVEFCPIDQLT 464
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf3 (TNF receptor associated factor 3 [Source:NCBI gene;Acc:101161601]) HSP 1 Score: 103.219 bits (256), Expect = 5.760e-23 Identity = 96/418 (22.97%), Postives = 177/418 (42.34%), Query Frame = 3
Query: 222 CTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKC-PETCG-DDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRN-----SRRKLLSYFPKQMKFL-----KTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYE--FKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
C C+ ++ + CG RFC C+ L+ CP D + F + +F D + I L++ C E G + + L Q+ +H+ +C PF + C M++ EI H + ++ E+T E K + E+++ KE + S P+ K + K + + ++ +R L ++S E + +E +N+ ++ ++ +E + ++ A + W I ++ ++++A +GK ++S PF + GY++ + NG G + +LS++ +M+G D L WPFK VT +++Q + H D P+S + RP NI G P F+S LE+ T I D+ I +K V
Sbjct: 48 CEACRLVLCQPRQTECGHRFCYSCINDILSCPNPVCPADME------PLFKDKIFRDVCCHREIMALKVYCRSEANGCQEQMSLQQIPDHVNVC-------PFFEVPCPLGKCKERMMRK----EIPEHLAWKCKYREST-CEFCKNKMPLTELQKHKETVCPAFPVSCPNHCTSSSLPRSEKLMSSHTEKLLELELELRSLRQLRDEMESLRGTLDTVRTRLSALEQGGRASLETQLNR-HDDMLSVHEIRLADMDLRFQVLETAS-YNGTLIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPD--PSSSSFRRPVAEMNIASGCPLFVSQSVLESGT-YIKDDTIFIKVTV 442 HSP 2 Score: 95.1301 bits (235), Expect = 2.502e-20 Identity = 51/160 (31.87%), Postives = 84/160 (52.50%), Query Frame = 3
Query: 1446 KLANTLHENGNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
++ T NG +IW ++++ + ++DA +GK L ++S+PFY+ GYKM +Y NG G +S++F +++G +D L WP+K V LMDQ + + + F D P + RP E ++ G F+S L I DD I +VT +
Sbjct: 289 QVLETASYNGT-LIWKIRDYKRRKQDAVAGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLPWPFKQKVTLMLMDQGPSRKHLGDAFKPD--PSSSSFRRPVAEMNIASGCPLFVSQSVLESG-TYIKDDTIFIKVTVDT 444
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 100.908 bits (250), Expect = 3.183e-22 Identity = 64/202 (31.68%), Postives = 105/202 (51.98%), Query Frame = 3
Query: 870 KTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
K+ + + N ++ QR E + +E+ S H W ++++S K + AK +E FS PF +H GY+L A NG+G+ E +LS+YI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P RN +G G+P FIS +E++ + I DN I +K + + K+
Sbjct: 268 KSHLTMMCNLVSRQRQEILELRREMEELSVS-------HDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRN-YIRDNCIFIKASIEIPQKI 461 HSP 2 Score: 88.5817 bits (218), Expect = 3.493e-18 Identity = 50/161 (31.06%), Postives = 86/161 (53.42%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPN----------RNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +S+Y +++ G +D+ LEWP+ V F ++DQ + T+ PD PN RN E +LGFG+ KFIS E++ I D+ I + + E+ +K
Sbjct: 303 LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPD-PNWKNFQKPCSTRNS-LDESTLGFGYPKFISHEEIKKR-NYIRDNCIFIKASIEIPQK 460
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 101.293 bits (251), Expect = 3.187e-22 Identity = 64/202 (31.68%), Postives = 105/202 (51.98%), Query Frame = 3
Query: 870 KTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKL 1451
K+ + + N ++ QR E + +E+ S H W ++++S K + AK +E FS PF +H GY+L A NG+G+ E +LS+YI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P RN +G G+P FIS +E++ + I DN I +K + + K+
Sbjct: 275 KSHLTMMCNLVSRQRQEILELRREMEELSVS-------HDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRN-YIRDNCIFIKASIEIPQKI 468 HSP 2 Score: 88.5817 bits (218), Expect = 3.541e-18 Identity = 48/159 (30.19%), Postives = 84/159 (52.83%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +S+Y +++ G +D+ LEWP+ V F ++DQ + T+ PD P R E +LGFG+ KFIS E++ I D+ I + + E+ +K
Sbjct: 310 LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKR-NYIRDNCIFIKASIEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: traf4a (TNF receptor associated factor 4 [Source:NCBI gene;Acc:101161428]) HSP 1 Score: 101.293 bits (251), Expect = 3.382e-22 Identity = 65/206 (31.55%), Postives = 106/206 (51.46%), Query Frame = 3
Query: 870 KTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLL--TYDMLPNSKEWNRPTQFRN------IGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKLANTL 1463
K+ + + N ++ QR E + +E+ S H W ++++S K + AK +E FS PF +H GY+L A NG+G+ E +LS+YI ++ G DN L WPF VTFSI++Q + + + T++ PN K + +P RN +G G+P FIS +E++ + I DN I +K + + K+ L
Sbjct: 275 KSHLTMMCNLVSRQRQEILELRREMEELSVS-------HDGVLIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKRN-YIRDNCIFIKASIEIPQKIMVIL 472 HSP 2 Score: 88.5817 bits (218), Expect = 4.199e-18 Identity = 48/159 (30.19%), Postives = 84/159 (52.83%), Query Frame = 3
Query: 1482 IIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPD-------HPNRNR-PFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
+IW + ++++ ++A+ + FS PFY+HR GYK+ + + NG +G +S+Y +++ G +D+ LEWP+ V F ++DQ + T+ PD P R E +LGFG+ KFIS E++ I D+ I + + E+ +K
Sbjct: 310 LIWKLNDYSRKLQEAKLRSNHEFFSPPFYTHRYGYKLQVSAFLNGNGSGEGSHLSVYIRVLPGEYDNLLEWPFSYKVTFSILDQSDPSLSKPQHITETFNPDPNWKNFQKPCSTRNSLDESTLGFGYPKFISHEEIKKR-NYIRDNCIFIKASIEIPQK 467
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Match: ENSORLT00000020861.2 (TNF receptor-associated factor 2 [Source:NCBI gene;Acc:101167626]) HSP 1 Score: 95.5153 bits (236), Expect = 3.977e-20 Identity = 50/166 (30.12%), Postives = 88/166 (53.01%), Query Frame = 3
Query: 1431 VHLDGKLANTLHENGNKI-IWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
V ++GK+ + + I IW + +FT+ R+DA +G+A +FS FY+ + GYKM L +Y NG TG +S++F +++G D L+WP+ V L+DQ+ N +++ F D+ + RP ++ ++ G F KL I D+ I + ++
Sbjct: 404 VEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQN-NREHIIDAFRPDI--SSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVDL 566 HSP 2 Score: 89.7373 bits (221), Expect = 2.497e-18 Identity = 83/384 (21.61%), Postives = 155/384 (40.36%), Query Frame = 3
Query: 438 ETCGDDFIELNQMEEHIRICNNQRRFCPFINIGC-------------QENNLVVLNMKQHLLSEIEVH-SSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKF----LKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGY-------------------QLEQEIHTSEKTKAEM-----------HQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDG 1445
E C I + +HI+ C+ + C F +GC ++ + LN+ H + I+V SL Q E ++ + + +++ ++ R+ L + L + + + + + TK+ + E ++S +E + I+N+ + E Y QLE+ + + + EM + F W I +F+ KR++A +G+ +FS F + + GY++ + NG G +LS++ +M+G +D L WPF VT +++Q +N H D+ +S + RP NI G P F +L+++ I D I +K V L G
Sbjct: 191 EGCAKKKIPREKYVDHIKFCSKFKAPCRFHVVGCDTSVEKEKIHDHERQCSYEHLNLLLHFIMGIKVSLESLQPQRLEVASQKLHELHQSLRDLELRMSQLGRSGTAPLQGVCAATLATSFTPLHSAMGAALELQLQSEKTKVAELSRRCQELELKVSTFE---NIVCILNRELERSCATMEAYNRQHRLDQDKIEILSNKVRQLERTVSLRDLSIVEMEGKMKDMSAATYDGIFIWKISDFTKKRQDAMAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQ-NNREHIIDAFRPDI--SSSSFQRPVSDMNIASGCPLFCPLSKLDSKNSYIRDETIFIKAIVDLSG 568
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000039062.1 (SMESG000039062.1) HSP 1 Score: 1226.08 bits (3171), Expect = 0.000e+0 Identity = 593/600 (98.83%), Postives = 597/600 (99.50%), Query Frame = 3
Query: 135 MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKINNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLDGKLANTLHENGNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 1934
MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQ+NEIKEIKEKINRN RRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNK+NNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNL WPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFIS KELETQTGLIVDN+IILKCKVHLDGKLANTLHENGNKIIWTVKNFTQLRKDAQSGKA+QIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK
Sbjct: 1 MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQINEIKEIKEKINRNPRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEIVNKMNNQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLPWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISLKELETQTGLIVDNKIILKCKVHLDGKLANTLHENGNKIIWTVKNFTQLRKDAQSGKAVQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEVQKK 600
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000020135.1 (SMESG000020135.1) HSP 1 Score: 277.33 bits (708), Expect = 4.706e-86 Identity = 164/463 (35.42%), Postives = 251/463 (54.21%), Query Frame = 3
Query: 135 MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEI----KEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEI--------------VNKINNQRINNYEGYQLEQEIHTSEK---TK-AEMHQN-------EFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVH 1436
M +FEN+W+I+ NY+F E+ D+ C +C K+MIN+ N+PCGCRFC DC+ YLN E CPG+ D CK LI+ + N+ D+P N++I+RL +KCPE D EL ++E HI CN+Q CP+I IGC E+++ + M HL ++I H+ LLM ID++ N++NEIK I K + ++N+ + SY + L+ +I +++ +HN EN + K K E + ++ +N N + +I + K TK A+M N EF W + F++K + AK GK IFSD F +H+ GY++ Q PNG+ Y N YLS+++C+MK D+ L WPF+ + TFS+INQ++ + HS+ TYD K ++P RN+G G+ F+ KEL +++I +K KVH
Sbjct: 1 MAKFKFENIWKIMENYDFS-GVEVDSDMICGLCGKVMINSHNAPCGCRFCLDCISNYLNGRENLCPGNKDDCKLELISLEENIAIDRPMNNKISRLIIKCPENSCDYVDELRKIELHISQCNSQTIICPYIKIGCNESDVSLGKMPDHLRNDIHNHTKLLMDC-------IDNLNNEMNEIKIIVGNFKGQFDKNTNDQ--SYLAEIESKLQQ------------QTMEIDLLKQRVHNLENLDFVDRPKLKAESLNNIISDNFRNYPNRLDTLNRNSTNPINLTAVSNKIDDAMKFGLTKLADMEINLKRMKSFEFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFIKFKVH 441 HSP 2 Score: 98.5969 bits (244), Expect = 1.299e-21 Identity = 50/151 (33.11%), Postives = 84/151 (55.63%), Query Frame = 3
Query: 1479 KIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDK--IAFRVTTEV 1925
+ +W V F K A+ GK L IFS+ FY+H+ GYKM L+L+PNG N +S++ ++K DD LEWP++ + F L++Q T P + T D ++P E+++G+G+ F+ ++L N +D+ I F+V + +
Sbjct: 294 EFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFIKFKVHSSL 444
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000025794.1 (SMESG000025794.1) HSP 1 Score: 268.085 bits (684), Expect = 1.489e-82 Identity = 150/457 (32.82%), Postives = 258/457 (56.46%), Query Frame = 3
Query: 135 MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKE-------KINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEF--KTKVEEIVNKI----NNQRINNYE-GYQLEQEIHTSEKTKAEMHQN-------EFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVHLD 1442
M + ENVW+I+R+YN+E +EI D+ C +CKK+++NA +PCGCRFC C+ +L+ EK CPGD++ CK+ +++ + N+ D P N +I++L++KC E EL +ME+H R C + CP+ NIGC + N+ + HL SEI H+ LLM + N NE++ +K N + + E ++ + R+ + Q K + +LN IP +R + N +++ + + +E+++KI N Q+++ E ++++ ++ EM N EF W + F++K +AK+G I+S+ FL+H+NG+++ + DP+G+G + +LS++ +MKG D L WPF+ +VTF++INQ++ + H + + PN K +PT RN G+GFP F+S +EL + L+ +N+I +KC V +D
Sbjct: 1 MSGSKLENVWQIMRDYNYESVTEIQNDMLCFLCKKLLVNARCAPCGCRFCFTCISDFLDHKEKICPGDTEECKQEMLHLNENICVDYPMNIKISKLQVKCKEMSCVYVDELRKMEDHSRTCKYRSVACPYSNIGCDKCNISQDKVTDHLQSEIFAHTKLLMDFVVNFNNEMEMLKANNNGLSAVNELLRNEINELKLDGERRRVEIADLQRKCADQ----AEEIELLN--EDIPALRNVDRNVSDRLDGLQLIIEGNQKELIDKIGQMENKQKVDLTEMSNKIDKLSGNVDRKLLEMAANQNQRINGEFMWKLDKFTDKMADAKNGINTRIYSESFLTHKNGFKMCLRVDPDGNGGGKGTHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKTVKCANYPNDKALIQPTD-RNAGLGFPKFVSHEELSSNPDLMRNNQIFIKCSVDID 450 HSP 2 Score: 107.842 bits (268), Expect = 1.428e-24 Identity = 53/158 (33.54%), Postives = 90/158 (56.96%), Query Frame = 3
Query: 1452 ANTLHENGNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTTEV 1925
AN + +W + FT DA++G +I+SE F +H+NG+KM L + P+G G +S++F ++KG D LEWP++ +V F L++Q T P V P+ +P T+++ G GF KF+S E+LS NP L+ +++I + + ++
Sbjct: 293 ANQNQRINGEFMWKLDKFTDKMADAKNGINTRIYSESFLTHKNGFKMCLRVDPDGNGGGKGTHLSVFFHLMKGEFDGILEWPFRHSVTFALINQRTRLPHVSKTVKCANYPNDKALIQP-TDRNAGLGFPKFVSHEELSSNPDLMRNNQIFIKCSVDI 449
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000020135.1 (SMESG000020135.1) HSP 1 Score: 260.381 bits (664), Expect = 8.433e-80 Identity = 158/451 (35.03%), Postives = 242/451 (53.66%), Query Frame = 3
Query: 171 LRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEI----KEKINRNSRRKLLSYFPKQMKFLKTFLVFTFYMLILNYATKIPIIRTILHNEENQISIYEFKTKVEEI--------------VNKINNQRINNYEGYQLEQEIHTSEK---TK-AEMHQN-------EFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKEWNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKVH 1436
+ NY+F E+ D+ C +C K+MIN+ N+PCGCRFC DC+ YLN E CPG+ D CK LI+ + N+ D+P N++I+RL +KCPE D EL ++E HI CN+Q CP+I IGC E+++ + M HL ++I H+ LLM ID++ N++NEIK I K + ++N+ + SY + L+ +I +++ +HN EN + K K E + ++ +N N + +I + K TK A+M N EF W + F++K + AK GK IFSD F +H+ GY++ Q PNG+ Y N YLS+++C+MK D+ L WPF+ + TFS+INQ++ + HS+ TYD K ++P RN+G G+ F+ KEL +++I +K KVH
Sbjct: 1 MENYDFS-GVEVDSDMICGLCGKVMINSHNAPCGCRFCLDCISNYLNGRENLCPGNKDDCKLELISLEENIAIDRPMNNKISRLIIKCPENSCDYVDELRKIELHISQCNSQTIICPYIKIGCNESDVSLGKMPDHLRNDIHNHTKLLMDC-------IDNLNNEMNEIKIIVGNFKGQFDKNTNDQ--SYLAEIESKLQQ------------QTMEIDLLKQRVHNLENLDFVDRPKLKAESLNNIISDNFRNYPNRLDTLNRNSTNPINLTAVSNKIDDAMKFGLTKLADMEINLKRMKSFEFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFIKFKVH 429 HSP 2 Score: 98.5969 bits (244), Expect = 1.280e-21 Identity = 50/151 (33.11%), Postives = 84/151 (55.63%), Query Frame = 3
Query: 1479 KIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNRNRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDK--IAFRVTTEV 1925
+ +W V F K A+ GK L IFS+ FY+H+ GYKM L+L+PNG N +S++ ++K DD LEWP++ + F L++Q T P + T D ++P E+++G+G+ F+ ++L N +D+ I F+V + +
Sbjct: 282 EFVWKVDKFNDKMKAAKKGKTLSIFSDSFYTHQYGYKMCLQLFPNGNAEYANNYLSVFLCLMKSDLDDILEWPFRNHFTFSLINQRTRLPHSRSTTTYDNFQMEKCLDKPILERNVGYGYLDFMDLKELFNNDDWTRNDQIFIKFKVHSSL 432
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Match: SMESG000014923.1 (SMESG000014923.1) HSP 1 Score: 259.225 bits (661), Expect = 3.627e-79 Identity = 152/443 (34.31%), Postives = 242/443 (54.63%), Query Frame = 3
Query: 135 MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCSDCLKTYLNRSEKFCPGDSDYCKRVLINFDNNVFCDQPTNHRIARLRLKCPETCGDDFIELNQMEEHIRICNNQRRFCPFINIGCQENNLVVLNMKQHLLSEIEVHSSLLMQWNENTKNEIDSIKNQVNEIKEIKEKINRNSRRKLLSYFPKQMKFLKTFLVFT-----FYMLILNYATKIPIIRTILHNEENQI--SIYEFKTKVEEIVNKIN-NQRINNYEGYQLEQEIHTSEKTKAEMHQNEFTWTIHNFSNKRENAKSGKVYEIFSDPFLSHENGYQLMFQADPNGSGNYENLYLSIYICIMKGSNDNNLLWPFKLNVTFSIINQKSNMVHSKRLLTYDMLPNSKE--WNRPTQFRNIGVGFPSFISFKELETQTGLIVDNRIILKCKV 1433
M ++R+EN+WRIL Y +EIS DL C ICK ++ NACN PCGCR+C +C+++YL + EKFCP + D CK L+N D N+ D N RI+R+ +KCPE + EL ++ +HI C+ + CP+ +IGC E + + HL+ + H+ L+ +N KNE+ +K E+K+IK++ ++ + L K +F + F+ + + + K+ +R L ++N + E + E++ K + NQR + +LE E + H W I NF+ KR+ A+SG + +I+S+PF SH+NGY++ Q P+G + LS++ IM+G ND L WP KL VT IINQ+S +H+ YD + + +++P N+G G+ FI EL L+ ++RI+LKC V
Sbjct: 1 MSNLRYENIWRILSEYRVNSMTEISSDLICVICKNLLKNACNGPCGCRYCFECIQSYLGQVEKFCPQNFDECKEELLNIDRNILLDNAANSRISRIIVKCPEPSCEFHDELRKIGDHINACDKKIVKCPYFDIGCSEGKVASERINDHLIVDNYTHAKTLVNCIQNLKNEMALMKECFEELKKIKDE-SQKKQSLLYDLQDKISEFKRKFIQKSDENIHLKLKLQQTEHKLEDLRHQLDMKQNATENQMIELLLENEKLKYKSDENQRFSEILHGKLES--LERETLSMKQHFGSIQWKIDNFTKKRKEAQSGIIADIYSEPFYSHKNGYKMCLQLHPDGFKAGKGTNLSVFFFIMRGENDVILQWPMKLEVTIGIINQESGDIHTSYKFNYDPVLDKYRHLFDKPKTDINVGYGY-DFIKLDELIKNNKLLKNDRIVLKCVV 439 HSP 2 Score: 111.309 bits (277), Expect = 7.527e-26 Identity = 59/169 (34.91%), Postives = 99/169 (58.58%), Query Frame = 3
Query: 1437 LDGKLAN------TLHENGNKIIWTVKNFTQLRKDAQSGKALQIFSEPFYSHRNGYKMILELYPNGINTGINEMVSIYFQIIKGPHDDKLEWPYKVNVVFELMDQHTNYPAVVNKFTDDLLPDHPNR--NRPFTEKSLGFGFEKFISFEKLSMNPGLIVDDKIAFRVTT 1919
L GKL + ++ ++ I W + NFT+ RK+AQSG I+SEPFYSH+NGYKM L+L+P+G G +S++F I++G +D L+WP K+ V +++Q + KF D + D ++P T+ ++G+G++ FI ++L N L+ +D+I +
Sbjct: 272 LHGKLESLERETLSMKQHFGSIQWKIDNFTKKRKEAQSGIIADIYSEPFYSHKNGYKMCLQLHPDGFKAGKGTNLSVFFFIMRGENDVILQWPMKLEVTIGIINQESGDIHTSYKFNYDPVLDKYRHLFDKPKTDINVGYGYD-FIKLDELIKNNKLLKNDRIVLKCVV 439 The following BLAST results are available for this feature:
BLAST of TNF receptor-associated factor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of TNF receptor-associated factor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of TNF receptor-associated factor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of TNF receptor-associated factor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of TNF receptor-associated factor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of TNF receptor-associated factor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of TNF receptor-associated factor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of TNF receptor-associated factor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025971 ID=SMED30025971|Name=TNF receptor-associated factor|organism=Schmidtea mediterranea sexual|type=transcript|length=1989bpback to top protein sequence of SMED30025971-orf-1 >SMED30025971-orf-1 ID=SMED30025971-orf-1|Name=SMED30025971-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=601bp MESIRFENVWRILRNYNFEVNSEISCDLKCTICKKIMINACNSPCGCRFCback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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