proton myo-inositol cotransporter
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025913 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A13 (solute carrier family 2 member 13 [Source:HGNC Symbol;Acc:HGNC:15956]) HSP 1 Score: 250.366 bits (638), Expect = 1.184e-74 Identity = 164/545 (30.09%), Postives = 263/545 (48.26%), Query Frame = 3
Query: 120 TNQFIHYIT-FPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKR---------NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTNKGNYSI------YNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +GGF+FGY TG V ++ +V++ G A +S+L G L FGR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +I+A+ L + R QN C+ + C++C L+ C +C ID N T + C N+ + YNF C +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+ N++ +L F +Y F++Y F G+ IY PET LE++
Sbjct: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL-SAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNF---CPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIE 606
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A13 (solute carrier family 2 member 13 [Source:HGNC Symbol;Acc:HGNC:15956]) HSP 1 Score: 122.479 bits (306), Expect = 4.355e-30 Identity = 83/281 (29.54%), Postives = 140/281 (49.82%), Query Frame = 3
Query: 120 TNQFIHYIT-FPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMY 863
T F++ + F +GGF+FGY TG V ++ +V++ G A +S+L G L FGR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ N T ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MY
Sbjct: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYL-----QKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMR----GNQT--IDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMY 346
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A12 (solute carrier family 2 member 12 [Source:HGNC Symbol;Acc:HGNC:18067]) HSP 1 Score: 117.087 bits (292), Expect = 4.332e-27 Identity = 128/551 (23.23%), Postives = 246/551 (44.65%), Query Frame = 3
Query: 129 FIHYITFPIIG---GFMFGYVTGTVPDVYGIFHM------FMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIA--VNLQL-FDVRYLKRNQN---------------NNCSNFLACDDCLNNICEYCQ---------ID---ENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI-FYAIFW---IYCAFTICGIALIYKYFPET-----NQIDLE--KMNYV 1565
F+ +T + G G+ G ++G + + + + +V+++ GALL+SL G L DR+GR+ IILS R IG+ + +SS +YIAEI P+ RG ++++ ++ + G+ LS+ ++ NYA L+ P + I M +P S R+L+ K + A +V+ +L+ + ++ E +I+ L+++ + + L R R +++G +L Q+ G +++YA+++ + + + + + + +IS+ A L+D +G + I + + S++ VNL + + ++ R+ N N +N D I + + +D E + + +N+G + T Y I ++ W+ L +++YV +F+IG+GP+PW+V SEI+P R MAL++ W NL+ +L F + + W IY ++ + + + PET QI +E K+NYV
Sbjct: 41 FLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGI-LSAYIS---NYAFANVFHGWKYMFGLVIPL--GVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTT---------EELTVIKSSLKDEYQYSFWDLFR--SKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIG-SSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTE---YQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYV 570
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A14 (solute carrier family 2 member 14 [Source:HGNC Symbol;Acc:HGNC:18301]) HSP 1 Score: 110.923 bits (276), Expect = 2.259e-25 Identity = 115/533 (21.58%), Postives = 217/533 (40.71%), Query Frame = 3
Query: 120 TNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFM------------------------VATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYA---IFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T I IT IG F FGY TG + I F+ VA + G ++ S G +RFGR+ ++++ R +IG+ G+ + P+YI EI+P +RG T+ Q+ + G+ ++ + L GS+ P++L +PA+ + PES R+LL ++ + + A ++++L ++++ ++ + + + + ++ Q + L R+ R+ +++ LQ+ QL GIN + YY+ +F+ ++ ++ T +N I + ++ L+++ GRR L +I L G+ CS ++ V+L L +N N S + C+ + ++++V F IG GPIPW + +E++ R MA++ + W N + L+F S +Y +F I+ F I +A + PET E +
Sbjct: 8 TPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLEL-----ILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGT--QDVSQDIQEMKDESARMSQEKQVTVLE----LFRV---SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA---GVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL-------LLKNHYNGMS-----------------------FVCIGA------------------------------ILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 463
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Match: SLC2A14 (solute carrier family 2 member 14 [Source:HGNC Symbol;Acc:HGNC:18301]) HSP 1 Score: 110.923 bits (276), Expect = 2.259e-25 Identity = 115/533 (21.58%), Postives = 217/533 (40.71%), Query Frame = 3
Query: 120 TNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFM------------------------VATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYA---IFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T I IT IG F FGY TG + I F+ VA + G ++ S G +RFGR+ ++++ R +IG+ G+ + P+YI EI+P +RG T+ Q+ + G+ ++ + L GS+ P++L +PA+ + PES R+LL ++ + + A ++++L ++++ ++ + + + + ++ Q + L R+ R+ +++ LQ+ QL GIN + YY+ +F+ ++ ++ T +N I + ++ L+++ GRR L +I L G+ CS ++ V+L L +N N S + C+ + ++++V F IG GPIPW + +E++ R MA++ + W N + L+F S +Y +F I+ F I +A + PET E +
Sbjct: 8 TPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLEL-----ILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGT--QDVSQDIQEMKDESARMSQEKQVTVLE----LFRV---SSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDA---GVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSL-------LLKNHYNGMS-----------------------FVCIGA------------------------------ILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 463
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.3 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q21455]) HSP 1 Score: 202.601 bits (514), Expect = 1.289e-57 Identity = 154/555 (27.75%), Postives = 260/555 (46.85%), Query Frame = 3
Query: 120 TNQFIHYITF-PIIGGFMFGYVTGTV-------PDVYGI------FHMFMVATIAGGALLSSLPTGYLADRFGRKKTII-LS*RFLIG---------------------IGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVE---NILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVN--------LQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGY------------------------TCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS----QIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +IGGF+FGY TG V P+ GI + +V+ G A + SL +G +D GRKK II S F IG + +G +S P+Y++E +P IRG+++T +Q+ +T GL +++++ +Y P ++ AVPA+ + L +PES RWL R EA EV+ ++ + TE+V+ N + + E + + + RIL RK +++G LQM QL GIN +MYY ++ + + +W + + IN + +F+ L++++GRR L L+S+ G+ + + V+ L+ FD + N N + + C N C++C DEN G+ T + +N TN G + D C + ++ M+ Y++SF+ G P+PWV+ +E YP W RST +++ST W+ NLI +L F S Y F+IYC T+ + ++ + PET ++++
Sbjct: 24 TGWFVYMLAFSAVIGGFLFGYDTGIVSAAMLYVPNASGIKPLDSVWQEIIVSITPGVAAIGSLCSGPGSDFLGRKKIIIGASVTFTIGAIICAAAWTKIILLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDP---DQVGWRLMFAFAAVPAIIQFVCFLFLPESPRWLYEHGRTVEAREVLTRIY----NGHTEWVDYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSN--CDFCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWE-DTYCHTKFTVLPIIIMVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEVE 568
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.3 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q21455]) HSP 1 Score: 202.601 bits (514), Expect = 1.289e-57 Identity = 154/555 (27.75%), Postives = 260/555 (46.85%), Query Frame = 3
Query: 120 TNQFIHYITF-PIIGGFMFGYVTGTV-------PDVYGI------FHMFMVATIAGGALLSSLPTGYLADRFGRKKTII-LS*RFLIG---------------------IGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVE---NILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVN--------LQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGY------------------------TCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS----QIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +IGGF+FGY TG V P+ GI + +V+ G A + SL +G +D GRKK II S F IG + +G +S P+Y++E +P IRG+++T +Q+ +T GL +++++ +Y P ++ AVPA+ + L +PES RWL R EA EV+ ++ + TE+V+ N + + E + + + RIL RK +++G LQM QL GIN +MYY ++ + + +W + + IN + +F+ L++++GRR L L+S+ G+ + + V+ L+ FD + N N + + C N C++C DEN G+ T + +N TN G + D C + ++ M+ Y++SF+ G P+PWV+ +E YP W RST +++ST W+ NLI +L F S Y F+IYC T+ + ++ + PET ++++
Sbjct: 24 TGWFVYMLAFSAVIGGFLFGYDTGIVSAAMLYVPNASGIKPLDSVWQEIIVSITPGVAAIGSLCSGPGSDFLGRKKIIIGASVTFTIGAIICAAAWTKIILLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYVDP---DQVGWRLMFAFAAVPAIIQFVCFLFLPESPRWLYEHGRTVEAREVLTRIY----NGHTEWVDYEINEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMYYTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVSFLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSN--CDFCVTDENCGFCESKVAKKGYCLPFPSDDSSDYSATGICEFSNLTNNGTDFEWE-DTYCHTKFTVLPIIIMVFYLLSFSAGYAPLPWVLNAEFYPLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYSIDEVE 568
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.1 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q9XXR3]) HSP 1 Score: 175.252 bits (443), Expect = 1.029e-47 Identity = 147/552 (26.63%), Postives = 242/552 (43.84%), Query Frame = 3
Query: 153 IIGGFMFGYVTGTV-------PDVYG------IFHMFMVATIAGGALLSSLPTGYLADRFGRKKTII----------------------LS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKL----KQIPESNITE---FVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNN---------------------NCSNFLACDDCLN-NICEYCQIDENS--GYTCVNSG----------ANCTNKGNYSIYNFDNP---CTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS--QIF--YAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
+IGGF+FGY T V PD G ++ +V+ G A + SL +G +D GR+K I+ L R L+GI +G +S P+Y+ E P +RG ++ + + ++FG ++++ +Y P + ++ AVP++ + + +PE+ RWL E EV+ K+ K+ E + E F E+ + N E+ ++ RIL K +G LQ QL GIN ++YY + + +N +W + LL+ N I FV LI+K+GRR + L FSC +++ ++L V +L N ++ C + CD C+ + C +C D N+ GY C+ +G +CTN NF C + ++ +Y+++F+ G +PWV+ SE YP W RST +A+ST + W+ NLI L + S Q+ Y FW+Y T+ I PET +E++
Sbjct: 33 VIGGFLFGYDTSVVSAAMLYMPDAPGLKPMDTVWQEVLVSISPGMAAVGSLMSGTSSDYIGRRKVILGASAIFTIGALVCAASVNKIMLLVGRVLLGIAIGFASMIVPVYLGETAPTHVRGMLVAAFALMISFGQVVANITGGAFSYIDPY---NVGWRLMFAFAAVPSIIQFVCFMFLPETPRWLYENGFETETREVLEKVYNGDKEWVEYEMAEIIAFNEDQAKEN--------EKAHASGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSSGISNNHTTIWISVLLSLCNFIGPFVPMSLIEKVGRRIIFL------FSCGLVV-LSLVFIGVAFLLVNHDSAATLPANQYGSNFNSSYPDAKGCMAYSNCDYCVTTDACGFCH-DANTKQGY-CLPAGFDNPEVYSSTGSCTNSNGSIANNFKWEKYYCDTKYTLLPIIACGVYLLTFSSGFTSLPWVLNSEFYPMWARSTCVAISTTSNWVFNLIIALTYLSLTQVIGKYGAFWLYAGLTVIAFIFILFLVPETKGYSIEEVE 564
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Match: hmit-1.2 (H(+) MyoInositol coTransporter [Source:UniProtKB/TrEMBL;Acc:Q9XXQ9]) HSP 1 Score: 175.252 bits (443), Expect = 1.286e-47 Identity = 147/547 (26.87%), Postives = 246/547 (44.97%), Query Frame = 3
Query: 153 IIGGFMFGYVTGTV-------PDVYGIFHM------FMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASP-TYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENIL---EANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQL--------FDVR-------YLKRNQNNNCSNFLACDDCL-NNICEYCQIDENSGYTCVNSGAN----------CTNKGNYSIYNFDNP---------CTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIF----YAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
IIGGF+FGY T V P+ G+ M +V+ G A + + +G +DR+GRK K ++L R +G+G+G +S P+Y+ E +P +RG +++ + + ++FG +++++ +Y P T G ++ +PAL + + +PE+ RWL ++A +V+ K+ TE++E L + + E++++ ++ RIL K +G LQ QL GIN ++YY + + N +W + +L+ NLI F I+K+GRRKL L S G+ V+I V+ L FD Y + +C CD C+ + C +C+ E C+ N CTN + S +F N CT + ++ M +Y+++F+ G +PWV+ SE YP W RST +++ST + W+ NLI L + S Y FW+Y FTI IY PET ++++
Sbjct: 34 IIGGFLFGYDTSVVSAAMLYVPEAPGLKPMGTVWKEVIVSITPGMAAVGAWFSGAGSDRYGRKPIIIGSTLIFVCGAVICAVAWTKIVMLIGRIFLGVGIGFASMVVPVYLGEASPTHVRGTLVSAFAMMISFGQVVANIMGGVFSYWEPYTIGWR----LMFAFAGIPALIQFVCFIFLPETPRWLYENGHTEQAEQVLEKIY----GGNTEWIEYELAEIKTYAEERQKQMEEEKKSGPVIWRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSAGIENYHTIIWISVILSICNLIGPFAPMFFIEKLGRRKLFLFSCAGVVVSLVLIGVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESCLMLSNCDSCVTSEHCGFCEDSETRTGFCLPVDHNDVTLYSSTGLCTNGLDKSNSSFPNATSYVWQKHHCTTSYTILPIVMMGVYLLTFSCGFTSLPWVLNSEFYPMWARSTCVSISTLSNWVFNLIIALTYLSLTHAITKYGAFWLYAIFTIIAFIFIYFLVPETTGYSIDEVE 572
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Match: R09B5.11 (Facilitated glucose transporter homolog [Source:UniProtKB/Swiss-Prot;Acc:O44616]) HSP 1 Score: 98.5969 bits (244), Expect = 1.015e-21 Identity = 101/434 (23.27%), Postives = 185/434 (42.63%), Query Frame = 3
Query: 228 VATIAGGALLSSLPTGYLADRFGRKKTI-------------------------ILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSK-NRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLID--KIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF 1442
V+ + G + S +G+LAD+FGRK T+ I+ RFL+G+ GI+S P+++ E+ P +RG+ + +Q+ ++ + LS + +G+ P I A+P L + ES ++L+SK N +EA ++ KL+ + + E +E++++ ++ E L + F GD + +++ + Q GI+ + +Y+ +F++ ++ N +Y T I LI++F LID K GR++L + L G+ S++I + L L N+GY +Y+N + +L +V++FA G GPIPW TSE++ + R A+S + W+ N + L F
Sbjct: 104 VSMFSVGGMFGSFCSGFLADKFGRKSTLLYNNILALLAAVCLSTSKLFNFYPMIVFGRFLVGLNCGITSGLVPMFLTELAPANLRGKCGSFHQLNISVAIVLSQALG-----LPQIFGTQVGWPYIFACVAIPTFLQLATIPFCVESPKYLISKLNDREEARRILEKLRG--HTKVDEELEHMVQETMVTVEPLHQPGYVSLF-----KGDN--QWPMIVSILMMFSQQFSGISAVTFYSTLIFKRNGLSGNEPMYA--TVGFGCIKLIATFGCLFLIDHPKFGRKRLHIAGLSGMCISSILIVITLTL----------------------------------SNAGYHWA----------------------SYMNVLFILS---FVVTFAFGPGPIPWFFTSELFDSATRGRAAAVSATSNWVANWMVGLTF 462
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333499) HSP 1 Score: 120.553 bits (301), Expect = 5.608e-29 Identity = 116/466 (24.89%), Postives = 198/466 (42.49%), Query Frame = 3
Query: 276 YLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLI--------------FTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
++A+RFGRK ++L+ RF+IG+ G++++ P+YI+EI P +RG + T+ Q+ +T GL LS V+ G++ PI+L PA+ LI + PES R+LL + +E E + L+++ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+F S+ I + +FL I E GY ++++++ ++ + +V+ FA+G G IPW++T+E++ R + MA++ W+ N + +T + FS +F AIFWI+ YK PET E++
Sbjct: 86 WMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLG-----IEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEE--EARKALRRLRASGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITI-------------------SFL--------------IKEFFGYV--------------------QEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFS-VFLAIFWIFT----------YKKVPETKNKTFEEI 473
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333500) HSP 1 Score: 120.553 bits (301), Expect = 1.061e-28 Identity = 118/467 (25.27%), Postives = 200/467 (42.83%), Query Frame = 3
Query: 276 YLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLI--------------FTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
++A+RFGRK ++L+ RF+IG+ G++++ P+YI+EI P +RG + T+ Q+ +T GL LS V+ G++ PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+F S+ I + +FL I E GY ++++++ ++ + +V+ FA+G G IPW++T+E++ R + MA++ W+ N + +T + FS +F AIFWI+ YK PET E++
Sbjct: 142 WMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLG-----IEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITI-------------------SFL--------------IKEFFGYV--------------------QEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFS-VFLAIFWIFT----------YKKVPETKNKTFEEI 529
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Match: Glut1 (gene:FBgn0264574 transcript:FBtr0333494) HSP 1 Score: 119.783 bits (299), Expect = 2.365e-28 Identity = 118/467 (25.27%), Postives = 200/467 (42.83%), Query Frame = 3
Query: 276 YLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLI--------------FTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
++A+RFGRK ++L+ RF+IG+ G++++ P+YI+EI P +RG + T+ Q+ +T GL LS V+ G++ PI+L PA+ LI + PES R+LL +K +EA + +R+L+ S E E+I E E ++C R L++G +Q+ Q GIN + YY+ SLF + + T + I ++ + V+ L+D+ GRR L L L G+F S+ I + +FL I E GY ++++++ ++ + +V+ FA+G G IPW++T+E++ R + MA++ W+ N + +T + FS +F AIFWI+ YK PET E++
Sbjct: 173 WMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLG-----IEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLITKQWEEEARKALRRLRA---SGSVE--EDIEEMRAEERAQQSESHISTMELIC----SPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTE-ESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITI-------------------SFL--------------IKEFFGYV--------------------QEMIDWMSYLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFS-VFLAIFWIFT----------YKKVPETKNKTFEEI 560
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Match: CG10960 (gene:FBgn0036316 transcript:FBtr0075943) HSP 1 Score: 96.6709 bits (239), Expect = 4.870e-21 Identity = 103/470 (21.91%), Postives = 184/470 (39.15%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIIL----------------------S*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIP---ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFF----SQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
GA +P G+L + GRK T++ + RF++GI G P+Y EI K IRG + + +Q+ +T G+ V A + + +I +P +F I +PES +L+SK+R + AI+ ++ L+ E + E E E K + L + RK L + L Q+ GIN +++YA+ +F + N W T L+ + ++++FV+ ++DK+GRR L L S + +A++ V + + Q+ A + G W+ + + L++I F+IG GP+PW++ E++ + +L+ + WL + T F FW++ T+ G+ +Y PET L ++ L
Sbjct: 69 GAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFW----------LSIICGILPLIFGAI-FFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKA------------NKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLE--ANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLAS-------GISMAISTTAIGVYFFLQKQD---------------------------------AAQVVSLG----------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQEL 457
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Match: CG10960 (gene:FBgn0036316 transcript:FBtr0075941) HSP 1 Score: 96.6709 bits (239), Expect = 4.870e-21 Identity = 103/470 (21.91%), Postives = 184/470 (39.15%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIIL----------------------S*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIP---ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFF----SQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
GA +P G+L + GRK T++ + RF++GI G P+Y EI K IRG + + +Q+ +T G+ V A + + +I +P +F I +PES +L+SK+R + AI+ ++ L+ E + E E E K + L + RK L + L Q+ GIN +++YA+ +F + N W T L+ + ++++FV+ ++DK+GRR L L S + +A++ V + + Q+ A + G W+ + + L++I F+IG GP+PW++ E++ + +L+ + WL + T F FW++ T+ G+ +Y PET L ++ L
Sbjct: 69 GAACVCIPIGFLINMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRGTLGSFFQLMITIGILFVYAVGAGVKIFW----------LSIICGILPLIFGAI-FFFMPESPTYLVSKDRSENAIKSIQWLRGKEYDYEPELAELRETDRETKA------------NKVNVWAALNRPVTRKALAISMGLMFFQQVCGINAVIFYASRIFLE--ANTGIEAEWATILIGIMQVVATFVSTLVVDKLGRRILLLAS-------GISMAISTTAIGVYFFLQKQD---------------------------------AAQVVSLG----------------WLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGTSNWLLAFVVTKTFVNLNDGLGIGGTFWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQEL 457
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a13b (solute carrier family 2 member 13b [Source:ZFIN;Acc:ZDB-GENE-090812-1]) HSP 1 Score: 249.98 bits (637), Expect = 3.508e-75 Identity = 164/538 (30.48%), Postives = 264/538 (49.07%), Query Frame = 3
Query: 147 FPIIGGFMFGYVTGTV----------PDVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLF-----DVRYLKRN---QNNNCSNFLACDDC-LNNICEYC--------------QID-ENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF*RI 1580
F +GGF+FGY TG V + ++ +V+ G A +S+L G+L RFGR+ K +L R +G+GLGI+S P+YIAE++P +RG+++T+ + +T G F++SVV+ +Y P G +L VPA +G L +PES RWLL K A+ V+R+++ + ++ E E+I +++ +L R+L AR+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W F N + + V L++++GRR+L + SL G +++A L V + N N+ C N+ C+ C L+ C +C +D N+ + N T K + S++ N C +W++LLG+ILY+ FA GMGP+PW V SEIYP W RST A S G W+CN++ +L F +Y F++Y A + G + PET + LE++ + R+
Sbjct: 41 FSALGGFLFGYDTGVVSGAMLLLKREKKLSSVWQELLVSITVGAAAVSALAGGFLNGRFGRRVCILLASFIFCAGGIILSVARNKEALLCGRLTVGLGLGIASMTVPVYIAEVSPPDLRGQLVTVNTLFITGGQFIASVVDGAFSYL-PHDGWR----FMLGLSVVPAALQFLGFLFLPESPRWLLQKGFTQNALLVLRQIRG--DVDVEEEFESIR-----CSIQEEQRDVAGGPVLWRMLASPPARRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVQDDQMAIWLAAGTAFTNFLFTLVGVWLVERVGRRRLTMASLLGTAVSLMVLAAGFLLSAQASPPVTFHPSNPSIHNSTCGNYGFCESCMLDPDCGFCYGLNATAVVQSSCVPVDPANTETAALGRCFNGTQKAS-SVFWAYNYCPTPYSWVVLLGLILYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAQYLTYYGAFFLYAALALLGFVFVSGCLPETKGLRLEEIESLFSRRL 565
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: SLC2A13 (proton myo-inositol cotransporter-like [Source:NCBI gene;Acc:101882338]) HSP 1 Score: 147.517 bits (371), Expect = 1.696e-39 Identity = 101/306 (33.01%), Postives = 150/306 (49.02%), Query Frame = 3
Query: 768 RILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFG------------IFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDC-LNNICEYCQIDENS----GYTCVNSGANCTNKGNYS--------------IYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF*RI 1580
R+L AR+ L++GC LQM QL GIN +MYY+ ++ Q + K+ +W + F N + + + L++++GRRKL L S+FG + S V L L D N++C+ L+C+ C L+ C YC ENS +CV T + + YNF C +W++LLG++LY+ SFA GMGP+PW V SEIYP W RST A S G W N++ +L F +Y +F++Y + G IY PET LE++ + R+
Sbjct: 2 RMLTFPPARRALIVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDKLAIWLVTVTAFTNFLFTLLGVWLVERVGRRKLTLGSIFGTVLSLCVLSVGFLLSAQHSPPVTLHLSD----PTTPNSSCAAHLSCEPCMLDPGCGYC-YQENSTAVFASSCVPVNPASTERAAWGKCSNSTHLPDSGIWAYNF---CPTSYSWVVLLGLVLYLASFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWTFNVLVSLTFLHMAQYLTYYGVFFLYTSLAFTGFFFIYGCLPETKGRRLEEIESLFENRL 299
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a8 (solute carrier family 2 member 8 [Source:ZFIN;Acc:ZDB-GENE-030829-25]) HSP 1 Score: 108.612 bits (270), Expect = 8.686e-25 Identity = 112/506 (22.13%), Postives = 211/506 (41.70%), Query Frame = 3
Query: 150 PIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPT----------GYLADRFGRK--------------KTIILS*--------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI----FYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
P+ GF+ GY + +P++ I + + ++ + S+ T G++ +R GRK TII + R L G+ G++S PLYI+E+ + +RG + + Q+ + G+ + V L++ + + ++P +L+ M +PE+ R+LL + + EA + +R L+ P++ I +A + E++ F L L D K L +G + +L Q GIN +M+YA ++F++ + + T ++ ++ + +A ++DK GR+ L ++S V++ ++ +F V + N S+ + + + E D P + + W+ + M ++ FAIG GP PW+V SEI+P R AL W C I T F + + FW++ A + + PET LE++
Sbjct: 47 PLSFGFVLGYSSPAIPELRRIQDLRLQLSVEEASWFGSVVTIGAALGGLLGGWIVERIGRKLSLMFCAIPFIFGFTTIIAAQNHWMFYVGRVLTGLASGVTSLVVPLYISEMAHERVRGTLGSCVQLMVVIGIMGAYVTGLFLDWR-----------WLAVASSIPPTLMLLSMCFMPETPRFLLCQGKRREAEDALRFLRG-PDAPAEWECARIEDA---------YKNEEQSFSLGD-LKDPGVYKPLGIGVMMMLLQQFTGINAIMFYAETIFEQAHFKSSDVA---TVIVAATQVVFTAIAALIMDKAGRKVLLILS-------GVVMCISEAVFGVYFKLTVMKPNNSSLTSVLTDTHGLLE------------------------------DQPSAD-LAWLAVGSMGFFIAGFAIGWGPTPWLVMSEIFPTRVRGLGSALCVLTNWTCAFIVTKTFQNLMDALSSAGTFWMFSALCASNVVFTAFFVPETKGKTLEEIQ 489
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a3b (solute carrier family 2 member 3b [Source:ZFIN;Acc:ZDB-GENE-121031-5]) HSP 1 Score: 103.219 bits (256), Expect = 6.205e-23 Identity = 108/468 (23.08%), Postives = 204/468 (43.59%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF---FSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
G ++ SL G L ++ G +K+++LS R +IG+ G+S+ P+Y+ EI P +RG T++Q+ + G+ ++ ++ GS T P++L A+PA+ I ++ ES R+LL S N+ DEA + + L+ E +I E + ++ ++ +K+ + + + R+ +++ LQ+ QL GIN +MYY+ +F+ I ++ T + +N + + V+ L+++ GRR L LI L G+ C +++ ++L+L D K N + ID S +++ + + +L + +V SF +G GPIPW + +E++ R MA++ W + + L+F +I +F I+ + I Y PET E +
Sbjct: 79 GGMIGSLSVGALVNKLGGRKSMLLSNILALIGGGLMGLSSICSSYELLIVGRLVIGVFCGLSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILG-----LESLLGSQTLWPLLLALTALPAVIQSIMLIFCLESPRYLLISLNKEDEARQALTSLRGHSDVEDDIREMKDEAMKMSM-----------EKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNA---GITEPVFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAI---------------IDSASPSEGIST----------------------VKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGLLFPILSKKIGAYVFIIFLILLVVFIVFTYFRVPETKGRTFEDI 490
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Match: slc2a3b (solute carrier family 2 member 3b [Source:ZFIN;Acc:ZDB-GENE-121031-5]) HSP 1 Score: 103.219 bits (256), Expect = 6.205e-23 Identity = 108/468 (23.08%), Postives = 204/468 (43.59%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIP--ESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF---FSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
G ++ SL G L ++ G +K+++LS R +IG+ G+S+ P+Y+ EI P +RG T++Q+ + G+ ++ ++ GS T P++L A+PA+ I ++ ES R+LL S N+ DEA + + L+ E +I E + ++ ++ +K+ + + + R+ +++ LQ+ QL GIN +MYY+ +F+ I ++ T + +N + + V+ L+++ GRR L LI L G+ C +++ ++L+L D K N + ID S +++ + + +L + +V SF +G GPIPW + +E++ R MA++ W + + L+F +I +F I+ + I Y PET E +
Sbjct: 79 GGMIGSLSVGALVNKLGGRKSMLLSNILALIGGGLMGLSSICSSYELLIVGRLVIGVFCGLSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILG-----LESLLGSQTLWPLLLALTALPAVIQSIMLIFCLESPRYLLISLNKEDEARQALTSLRGHSDVEDDIREMKDEAMKMSM-----------EKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNA---GITEPVFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAI---------------IDSASPSEGIST----------------------VKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGLLFPILSKKIGAYVFIIFLILLVVFIVFTYFRVPETKGRTFEDI 490
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: phf21b (PHD finger protein 21B [Source:Xenbase;Acc:XB-GENE-969993]) HSP 1 Score: 225.328 bits (573), Expect = 1.146e-65 Identity = 163/560 (29.11%), Postives = 257/560 (45.89%), Query Frame = 3
Query: 96 AGNIEVLYTNQFIHYIT---------FPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSS--------------LPTGYLADR------------------FGRKKTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFG------------IFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDC-LNNICEYCQIDENSG---YTCVNSGANCTNKGNY-------------SIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEK 1553
AG++E QF +T F +GGF+FGY TG V + M + LL S + G L R R K +L R ++G+G+GI+S P+YIAE P +RGR++TI + +T G F ++VV+ +Y + +L AVPA+ +G L +PES RWL+ K + +A V+ +++ I E ++I + ++ +++ I+ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q ++ ++ +W + F N + + L++K+GRRKL L SL G + S V V D N+ C+ + C+ C L+ C +C S +C+ + T++ + SI+ + N C +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+CN++ +L F +Y F++Y G+ IY PET LE+
Sbjct: 59 AGDLERAARKQFQQDVTPAFVYVVSVFSALGGFLFGYDTGVVSGAMLLLKREMNLSALWQELLVSSTVGAAALSALAGGVLNGVLGRRPCILMASLLFTAGAVILAAARDKETLLGGRVVVGLGIGIASMTVPVYIAEAAPPHLRGRLVTINTLFITGGQFSAAVVDGAFSYLA-----RDGWRYMLGLSAVPAVLQFLGFLFLPESPRWLIQKGQTQKARRVLSQIRG--NQTIDEEYDSIKNS----IDEEEKEGATGGPIIYRMLIYPPTRRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVDDDRLAIWLAAVTAFTNFSFTLLGVWLVEKLGRRKLTLGSLTGTTVALFVLALGFLLSAQVSPPVTFTPGD----PSGPNSTCTQYSYCNKCMLDPNCGFCYKKNGSSIVDSSCIPVNTDSTDRAAWGRCMNETKSKAGGSIWAY-NYCPTSYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGVNWICNVLISLTFLHTAEYLTYYGAFFLYAGLACVGLIFIYGCLPETKGKKLEE 602
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: phf21b (PHD finger protein 21B [Source:Xenbase;Acc:XB-GENE-969993]) HSP 1 Score: 211.846 bits (538), Expect = 1.656e-60 Identity = 157/547 (28.70%), Postives = 250/547 (45.70%), Query Frame = 3
Query: 96 AGNIEVLYTNQFIHYIT---------FPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSS--------------LPTGYLADR------------------FGRKKTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFG------------IFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDC-LNNICEYCQIDENSG---YTCVNSGANCTNKGNY-------------SIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFT---ICGIA 1505
AG++E QF +T F +GGF+FGY TG V + M + LL S + G L R R K +L R ++G+G+GI+S P+YIAE P +RGR++TI + +T G F ++VV+ +Y + +L AVPA+ +G L +PES RWL+ K + +A V+ +++ I E ++I + ++ +++ I+ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q ++ ++ +W + F N + + L++K+GRRKL L SL G + S V V D N+ C+ + C+ C L+ C +C S +C+ + T++ + SI+ + N C +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+CN++ +L F +Y F++Y CG +
Sbjct: 59 AGDLERAARKQFQQDVTPAFVYVVSVFSALGGFLFGYDTGVVSGAMLLLKREMNLSALWQELLVSSTVGAAALSALAGGVLNGVLGRRPCILMASLLFTAGAVILAAARDKETLLGGRVVVGLGIGIASMTVPVYIAEAAPPHLRGRLVTINTLFITGGQFSAAVVDGAFSYLA-----RDGWRYMLGLSAVPAVLQFLGFLFLPESPRWLIQKGQTQKARRVLSQIRG--NQTIDEEYDSIKNS----IDEEEKEGATGGPIIYRMLIYPPTRRALIVGCGLQMFQQLAGINTVMYYSATILQMSGVDDDRLAIWLAAVTAFTNFSFTLLGVWLVEKLGRRKLTLGSLTGTTVALFVLALGFLLSAQVSPPVTFTPGD----PSGPNSTCTQYSYCNKCMLDPNCGFCYKKNGSSIVDSSCIPVNTDSTDRAAWGRCMNETKSKAGGSIWAY-NYCPTSYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGVNWICNVLISLTFLHTAEYLTYYGAFFLYAGLARLCTCGAS 589
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 122.865 bits (307), Expect = 3.086e-29 Identity = 133/532 (25.00%), Postives = 223/532 (41.92%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVYGIFHMF----------MVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWL--LSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLAL-------ISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCV-----NSGANCTNKGNYSIYNFDNPC--------TNY--INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFY-AIFWIYCAFTICG---IALIYKYFPETNQIDLEKMN 1559
T ++GG +FGY G + + +V+ + GALL+SL G + DR+GR+ I+ S R IG + ISS C +Y++EI RG ++++Y+ +T G+ +S +N L+ G + + + VPA F I +L +P L ++ D IE L++ E+ EF + + F+ D + +TL +G L + Q G ++YYA+++FQ + + + L + + S+ +A DK GRR L L I++ GI S + ++ RN ++ SN ++ +NS + S AN + + + + ++ +NY +NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A W NL+ TL F I + W + + + G IA IY + PET LE+++
Sbjct: 13 TVSLLGGIVFGYELGIISGALLVLKTVYQLTCFEQEALVSAVLFGALLASLIGGIIIDRWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYVSEIVRPHQRGMLVSLYETGITVGILISYAMNYFLS------GVNESWKYMFGLAIVPAAFQFISILFLPSKPHKLNFWEQDTDDGFIE----LEETGEAG--EFKPDTYDRQ-------------YTFLDLFRSKDNMRTRTL-LGLGLVLFQQFTGQPNVLYYASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKAGRRILLLAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQLLGIVHAETSTINTLDNSVHQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEID 518
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 122.865 bits (307), Expect = 3.211e-29 Identity = 133/532 (25.00%), Postives = 223/532 (41.92%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVYGIFHMF----------MVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWL--LSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLAL-------ISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCV-----NSGANCTNKGNYSIYNFDNPC--------TNY--INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFY-AIFWIYCAFTICG---IALIYKYFPETNQIDLEKMN 1559
T ++GG +FGY G + + +V+ + GALL+SL G + DR+GR+ I+ S R IG + ISS C +Y++EI RG ++++Y+ +T G+ +S +N L+ G + + + VPA F I +L +P L ++ D IE L++ E+ EF + + F+ D + +TL +G L + Q G ++YYA+++FQ + + + L + + S+ +A DK GRR L L I++ GI S + ++ RN ++ SN ++ +NS + S AN + + + + ++ +NY +NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A W NL+ TL F I + W + + + G IA IY + PET LE+++
Sbjct: 13 TVSLLGGIVFGYELGIISGALLVLKTVYQLTCFEQEALVSAVLFGALLASLIGGIIIDRWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYVSEIVRPHQRGMLVSLYETGITVGILISYAMNYFLS------GVNESWKYMFGLAIVPAAFQFISILFLPSKPHKLNFWEQDTDDGFIE----LEETGEAG--EFKPDTYDRQ-------------YTFLDLFRSKDNMRTRTL-LGLGLVLFQQFTGQPNVLYYASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKAGRRILLLAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQLLGIVHAETSTINTLDNSVHQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEID 518
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Match: slc2a10 (solute carrier family 2 (facilitated glucose transporter), member 10 [Source:NCBI gene;Acc:780388]) HSP 1 Score: 122.479 bits (306), Expect = 3.911e-29 Identity = 133/532 (25.00%), Postives = 223/532 (41.92%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVYGIFHMF----------MVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWL--LSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLAL-------ISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCV-----NSGANCTNKGNYSIYNFDNPC--------TNY--INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFY-AIFWIYCAFTICG---IALIYKYFPETNQIDLEKMN 1559
T ++GG +FGY G + + +V+ + GALL+SL G + DR+GR+ I+ S R IG + ISS C +Y++EI RG ++++Y+ +T G+ +S +N L+ G + + + VPA F I +L +P L ++ D IE L++ E+ EF + + F+ D + +TL +G L + Q G ++YYA+++FQ + + + L + + S+ +A DK GRR L L I++ GI S + ++ RN ++ SN ++ +NS + S AN + + + + ++ +NY +NWI LL M+ +V +F+IG GP+ W+V SEIYPA R A W NL+ TL F I + W + + + G IA IY + PET LE+++
Sbjct: 23 TVSLLGGIVFGYELGIISGALLVLKTVYQLTCFEQEALVSAVLFGALLASLIGGIIIDRWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYVSEIVRPHQRGMLVSLYETGITVGILISYAMNYFLS------GVNESWKYMFGLAIVPAAFQFISILFLPSKPHKLNFWEQDTDDGFIE----LEETGEAG--EFKPDTYDRQ-------------YTFLDLFRSKDNMRTRTL-LGLGLVLFQQFTGQPNVLYYASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKAGRRILLLAGCIVMTIAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQLLGIVHAETSTINTLDNSVHQLAMAIRSPSLANSASSNHKDLISQNSTVLPASPELPSNYTILNWITLLSMMAFVSAFSIGFGPMTWIVLSEIYPADIRGRAFAFCNSFNWAANLLITLTFLDVIASIGLSWTFLLYGVVGLLAIAFIYFFIPETKGQSLEEID 528
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a13 (solute carrier family 2 (facilitated glucose transporter), member 13 [Source:MGI Symbol;Acc:MGI:2146030]) HSP 1 Score: 231.876 bits (590), Expect = 6.482e-68 Identity = 161/536 (30.04%), Postives = 257/536 (47.95%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKR---------NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTN------KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
F +GGF+FGY TG V ++ +V+ G A +++L G L GR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ LV+GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +I+A+ L + R +QN C+ + C++C L+ C +C ID N T + C N +G + Y+F C +W L+G++LY++ FA GMGP+PW V SEIYP W RST A S G W+ N++ +L F +Y F++Y F G+ +Y PET LE++
Sbjct: 75 AFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEATAAGP----IICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGF-LLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSF---CPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIE 595
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a12 (solute carrier family 2 (facilitated glucose transporter), member 12 [Source:MGI Symbol;Acc:MGI:3052471]) HSP 1 Score: 111.694 bits (278), Expect = 1.485e-25 Identity = 129/557 (23.16%), Postives = 234/557 (42.01%), Query Frame = 3
Query: 129 FIHYITFPIIG---GFMFGYVTGTVPDVYGIFHM------FMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICE--------------------YCQIDENSGYTCVNSGANCTNKGNY----SIYNFDNPCTNY------------INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS-QIFYAIFW---IYCAFTICGIALIYKYFPETN-------QIDLEKMNYV 1565
F+ +T I G G+ G ++G + + + + +V+++ GA L+SL G L DR+GR+ IILS R IG+ + +SS +YIAEI P+ RG ++++ ++ + G+ + + NYA + L+ P + I M +P S R+L+ K + + A +V+RKL+ I ++ E LI+ L+++ + + L R R +++G +L Q G +++YA+++ + + + + + + ++S+ A L+D IG + F C ++ L + + N N N +N LN E + +I S + + G KG S+ N T + W+ L +++YV +F+IG+GP+PW+V SEI+P R MAL++ W NL+ +L F + + W IY ++ +A + + PET ++L K NYV
Sbjct: 45 FLTSVTAAISGLLVGYELGLISGALLQIRTLLALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYIS----NYAFANISNGWKYMFGLVIPL--GVLQAIAMYFLPPSPRFLVMKGQEESAGKVLRKLRVISDTT---------EELTLIKSSLKDEYQYSFWDLFR--SKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGSKT---------FLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQISVELAKANYV 575
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a2 (solute carrier family 2 (facilitated glucose transporter), member 2 [Source:MGI Symbol;Acc:MGI:1095438]) HSP 1 Score: 101.293 bits (251), Expect = 2.937e-22 Identity = 88/312 (28.21%), Postives = 153/312 (49.04%), Query Frame = 3
Query: 228 VATIAGGALLSSLPTGYLADRFGRKKT-------------------------IILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPES-----NITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFD 1073
V++ A G +++S G+L D+ GR K +I++ R + G+ G+ S P+YI EI P +RG + T++Q+ L G+ +S + A L++ G+ I+L AVPAL + +L PES R+L K ++E + + LK++ + +I E + EA+ ++K + ++ D R+ +++ L M Q GING+ YY+ S+FQ T I ++ T + IN+I + V+ L++K GRR L L + G+F C++ ++V L L D
Sbjct: 100 VSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLSLTGALLMGCSKFGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTTLRGALGTLHQLALVTGILISQI--AGLSF---ILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYIK--LEEEVRAKKSLKRLRGTEDVTKDINEMKKEKEEAST-----------EQKVSVIQLFTDANYRQPILVALMLHMAQQFSGINGIFYYSTSIFQ---TAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMFFCTIFMSVGLVLLD 390 HSP 2 Score: 54.299 bits (129), Expect = 2.722e-7 Identity = 30/103 (29.13%), Postives = 51/103 (49.51%), Query Frame = 3
Query: 1263 YINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICGIALIYKYF-----PETNQIDLEKM 1556
+++++ + + L+V F IG GPIPW + +E + R T +AL+ + W+CN + L F Q Y F G+ L++ F PET E++
Sbjct: 394 WMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFVIALCF--QYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEI 494
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a3 (solute carrier family 2 (facilitated glucose transporter), member 3 [Source:MGI Symbol;Acc:MGI:95757]) HSP 1 Score: 98.9821 bits (245), Expect = 1.404e-21 Identity = 118/532 (22.18%), Postives = 214/532 (40.23%), Query Frame = 3
Query: 120 TNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFM------------------------VATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYA---IFWIYCAFTICGIALIYKYFPETNQIDLEKM 1556
T + +T IG F FGY TG + I F+ VA + G ++ S G +RFGR+ +++L R LIGI G+ + P+YI E++P +RG T+ Q+ + G+ ++ + L++ GS+ P +L +PA+ + PES R+LL +K D+A E++++L S++ + ++ + + +V + ++ Q + + + L++ LQ+ QL GIN + YY+ +F+ ++ ++ T +N I + V+ L+++ GRR L +I L G +AV CS F+ L K +Y +F + ++ +++YV F IG GPIPW + +E++ R +A++ W N + ++F S Y +F I+ AF I + + PET E +
Sbjct: 7 TPSLVFAVTVATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFG--LDF---ILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINKKEEDQATEILQRLWGT--SDVVQEIQEMKDESVRMSQEKQVT-------VLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKD---AGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGG-------MAV-----------------CSVFMTISLLL--------------------------KDDYEAMSF----------VCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDI 461
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Match: Slc2a1 (solute carrier family 2 (facilitated glucose transporter), member 1 [Source:MGI Symbol;Acc:MGI:95755]) HSP 1 Score: 95.1301 bits (235), Expect = 2.695e-20 Identity = 72/308 (23.38%), Postives = 148/308 (48.05%), Query Frame = 3
Query: 228 VATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLL-SKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFD 1073
VA + G ++ S G +RFGR+ ++++ RF+IG+ G+++ P+Y+ E++P +RG + T++Q+ + G+ ++ V G+ P++L +PAL I + PES R+LL ++N + A V++KL+ +++T ++ + E + + + + + R+ +++ LQ+ QL GIN + YY+ S+F+K ++ ++ T +N + V+ ++++ GRR L LI L G+ C+V++ + L L +
Sbjct: 69 VAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVAAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFG-----LDSIMGNADLWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGT--ADVTRDLQEMKEEGRQMMREKKVT-------ILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK---AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLE 359
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q96QE2|MYCT_HUMAN (Proton myo-inositol cotransporter OS=Homo sapiens OX=9606 GN=SLC2A13 PE=1 SV=3) HSP 1 Score: 250.366 bits (638), Expect = 5.687e-74 Identity = 164/545 (30.09%), Postives = 263/545 (48.26%), Query Frame = 3
Query: 120 TNQFIHYIT-FPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKR---------NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTNKGNYSI------YNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +GGF+FGY TG V ++ +V++ G A +S+L G L FGR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L AVPA+ G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +I+A+ L + R QN C+ + C++C L+ C +C ID N T + C N+ + YNF C +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+ N++ +L F +Y F++Y F G+ IY PET LE++
Sbjct: 77 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVL-SAQVSPRITFKPIAPSGQNATCTRYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKFKTEDIFWAYNF---CPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIE 606
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q3UHK1|MYCT_MOUSE (Proton myo-inositol cotransporter OS=Mus musculus OX=10090 GN=Slc2a13 PE=1 SV=2) HSP 1 Score: 231.876 bits (590), Expect = 4.534e-67 Identity = 161/536 (30.04%), Postives = 257/536 (47.95%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKR---------NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTN------KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
F +GGF+FGY TG V ++ +V+ G A +++L G L GR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ LV+GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +I+A+ L + R +QN C+ + C++C L+ C +C ID N T + C N +G + Y+F C +W L+G++LY++ FA GMGP+PW V SEIYP W RST A S G W+ N++ +L F +Y F++Y F G+ +Y PET LE++
Sbjct: 75 AFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEATAAGP----IICRMLSYPPTRRALVVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGF-LLSAQVSPRVTFRPTTPSDQNTTCTGYSYCNECMLDPDCGFCYKINGSAVIDSSCVPVNKASTTEAAWGRCDNETKFKAEGAHWAYSF---CPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIE 595
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q921A2|MYCT_RAT (Proton myo-inositol cotransporter OS=Rattus norvegicus OX=10116 GN=Slc2a13 PE=1 SV=2) HSP 1 Score: 226.483 bits (576), Expect = 4.199e-65 Identity = 159/536 (29.66%), Postives = 253/536 (47.20%), Query Frame = 3
Query: 144 TFPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKR---------NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTNKGNYSI------YNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
F +GGF+FGY TG V ++ +V+ G A +++L G L GR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L A+PA+ +G L +PES RWL+ K + +A ++ +++ I E ++I + E++ I+CR+L R+ L +GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G I+A+ L + R QN C+ + C++C L+ C +C ID N T + C N+ + Y+F C +W L+G++LY++ FA GMGP+PW V SEIYP W RST A S G W+ N++ +L F +Y F++Y F G+ +Y PET LE++
Sbjct: 75 AFSALGGFLFGYDTGVVSGAMLLLRRQMRLGAMWQELLVSGAVGAAAVAALAGGALNGALGRRSAILLASALCTVGSAVLAAAANKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAIPAVIQFLGFLFLPESPRWLIQKGQTQKARRILSQMRG--NQTIDEEYDSIRNSIEEEEKEASAAGP----IICRMLSYPPTRRALAVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASITAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALTILALGF-LLSAQVSPRVTFRPTAPSGQNATCTEYSYCNECMLDPDCGFCYKINSSAVIDSSCVPVNKASTNEAAWGRCENETKFKAEDVHWAYSF---CPTPYSWTALVGLVLYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFVYGCLPETKGKKLEEIE 595
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|Q9ZQP6|INT3_ARATH (Probable inositol transporter 3 OS=Arabidopsis thaliana OX=3702 GN=INT3 PE=2 SV=1) HSP 1 Score: 182.185 bits (461), Expect = 3.233e-49 Identity = 140/547 (25.59%), Postives = 247/547 (45.16%), Query Frame = 3
Query: 156 IGGFMFGYVTGTVP-------------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDK--------IARKTLVMGCSLQMLAQLIGINGLMYYANSLFQ--KYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAV-------NLQLFDVRYLKRN--QNNNCSNFLA------------CDDCLNNICEYCQ--IDENSGYTCVNSGAN----CTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI----FYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
IGG +FGY TG + D +V+ GA++ + G+ D+FGR+ +++++ R L+G G+G++S PLYI+E++P IRG +++ + +T G FLS ++N + T+ +L A+PA+ MLT+PES RWL +R E+ +++ ++ + ++EA + ++ + + I+ DK + R L G ++Q+ Q +GIN +MYY+ ++ Q Y +N + L + + +N + S V+ +D+ GRRKL +IS+FGI +C VI+A + D R RN +N C F C CL C +C E + C+ A+ C +KG F + C + ++ ++ + LY+I +A GMG +PW+V SEIYP R ++ + W+ NL+ + F + F ++ + G+ I+ PET + E++ +L
Sbjct: 35 IGGLLFGYNTGVIAGALLYIKEEFGEVDNKTWLQEIIVSMTVAGAIVGAAIGGWYNDKFGRRMSVLIADVLFLLGALVMVIAHAPWVIILGRLLVGFGVGMASMTSPLYISEMSPARIRGALVSTNGLLITGGQFLSYLINLAFVHTPGTW------RWMLGVSAIPAIIQFCLMLTLPESPRWLYRNDRKAESRDILERI----------YPAEMVEAEIAALKESVRAETADEDIIGHTFSDKLRGALSNPVVRHGLAAGITVQVAQQFVGINTVMYYSPTILQFAGYASNKTAMALAL--ITSGLNAVGSVVSMMFVDRYGRRKLMIISMFGIITCLVILAAVFNEASNHAPKIDKRD-SRNFAKNATCPAFAPFTASRSPPSNWNCMKCLQYDCGFCSNGAQEYAPGACIVQSADMKALCHSKGRTF---FKDGCPSKFGYLAIVFLGLYIIVYAPGMGTVPWIVNSEIYPLRYRGLAGGIAAVSNWMSNLVVSETFLTLTNAVGSSGTFLLFAGSSAVGLFFIWLLVPETKGLQFEEVEKLL 559
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Match: sp|O23492|INT4_ARATH (Inositol transporter 4 OS=Arabidopsis thaliana OX=3702 GN=INT4 PE=1 SV=1) HSP 1 Score: 178.718 bits (452), Expect = 6.167e-48 Identity = 139/538 (25.84%), Postives = 248/538 (46.10%), Query Frame = 3
Query: 156 IGGFMFGYVTGTVP-------------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSL--FQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAV----------NLQLFDVRYLKRNQNNNCSNFLA----------CDDCLNNICEYCQ--IDENSGYTCV----NSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFY----AIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
IGG +FGY TG + D +V+ GA++ + G++ D+FGR+ +I+++ R +G G+G++S PLYI+E +P IRG +++ + +T G F S ++N + T+ +L VPA+ + ML++PES RWL K+RI E+ ++ ++ P + +E + + + D + L G+ + R+ L G ++Q+ Q +GIN +MYY+ S+ F Y +N + L + + + +N + S V+ +D+ GRRKL +IS+FGI +C +I+A + F+ R N + LA C CL + C +C + + CV + A C+++G F + C + ++ ++ + LY++ +A GMG +PW+V SEIYP R ++ + W+ NLI + F S F ++ F+ G+ I+ PET + E++ +L
Sbjct: 36 IGGLLFGYDTGVISGALLFIKEDFDEVDKKTWLQSTIVSMAVAGAIVGAAVGGWINDKFGRRMSILIADVLFLIGAIVMAFAPAPWVIIVGRIFVGFGVGMASMTSPLYISEASPARIRGALVSTNGLLITGGQFFSYLINLAFVHTPGTW------RWMLGVAGVPAIVQFVLMLSLPESPRWLYRKDRIAESRAILERI--YPADEVEAEMEALKLSVEAEKADEAIIGDSFSAKLKGAFGNPVVRRGLAAGITVQVAQQFVGINTVMYYSPSIVQFAGYASNKTAMAL--SLITSGLNALGSIVSMMFVDRYGRRKLMIISMFGIIACLIILATVFSQAAIHAPKIDAFESRTFAPNATCSAYAPLAAENAPPSRWNCMKCLRSECGFCASGVQPYAPGACVVLSDDMKATCSSRGRT---FFKDGCPSKFGFLAIVFLGLYIVVYAPGMGTVPWIVNSEIYPLRYRGLGGGIAAVSNWVSNLIVSESFLSLTHALGSSGTFLLFAGFSTIGLFFIWLLVPETKGLQFEEVEKLL 560
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Match: A0A0H3YJX4 (Slc2a-9 (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc2a-9 PE=2 SV=1) HSP 1 Score: 931.398 bits (2406), Expect = 0.000e+0 Identity = 483/539 (89.61%), Postives = 494/539 (91.65%), Query Frame = 3
Query: 12 EFIVILNFIFICSFILMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*--------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
EFIVILNFIFICSF LMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFL+SVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIEEDLQEQKEQKKFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGI S SVIIAVNLQL DVRYLKRNQNNNC NFL+CDDC+NNICEYCQIDENSGYTCVN GANCTNKGNY IYNFDN CTN INWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALST A WLCNL T+ F++ Y FWIY AFTICGIALIYK FPE NQ ++E++ +VL
Sbjct: 1 EFIVILNFIFICSFNLMNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILSCLFYIVGSLISFNYRVVIAVGRFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIEEDLQEQKEQKKFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIISSSVIIAVNLQLVDVRYLKRNQNNNCRNFLSCDDCINNICEYCQIDENSGYTCVNYGANCTNKGNYPIYNFDNHCTNNINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTAKWLCNLTVTMTVFTRRLYETFWIYSAFTICGIALIYKNFPEMNQANMEEILHVL 539
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Match: A0A0H3YIU7 (Slc2a-10 OS=Schmidtea mediterranea OX=79327 GN=slc2a-10 PE=2 SV=1) HSP 1 Score: 377.481 bits (968), Expect = 2.453e-121 Identity = 217/561 (38.68%), Postives = 326/561 (58.11%), Query Frame = 3
Query: 60 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPD----VYGIFHMFMVAT---IAG---GALLSSLPTGYLADRFGRKKT----------------------IILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRN--QNNNCSNFLACDDCL-NNICEYCQIDE---------------NSGYTCVNSGANCTNKGNY----SIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
MN + S ++L + N ++ + FI I FPIIGGFMFGY TG + + FH+ ++ ++G A LSSL TG+L+D GRKKT +++ R +G G+GIS+ CCP+YIAE++P IRGR+I IYQI +T G+F +++V+A+ Y +L A+P+ IGMLTVPESYRWLLSKN++DEA ++ Q+PE ITE+++ I+ AN I+ ++E + + ++ +I + +AR++L++GC LQML Q+IGIN +MYY + + +I LW + L+ F N I SF+ + LIDKIGRRKL++ SL + + IA+ Q+ + K NN C + C++C+ ++ C +C I + ++ +S C+ + +I+N+D C + +W++++G+ILY+ISF+IGMGPIPW +TSEIYP WCRSTNMALST W+ NLI +L F S Y FW+Y +F GI IYK+ PETNQ LE++N +L
Sbjct: 1 MNSDSSSENLLISENFKIRNSRSFIWQIIFPIIGGFMFGYDTGVISGALLLIRDHFHLSTISQEIVVSGTVLSAALSSLITGWLSDWIGRKKTIIISCICFIIGSIIMGISQNFIMLVFGRIFVGFGVGISAACCPVYIAEVSPHQIRGRLIVIYQISITGGMFFAALVDASFFYLG-----KEGWRYMLGGAAIPSFIEFIGMLTVPESYRWLLSKNKVDEARTIIVNQGQVPEERITEYIDEIVRANQQIQMQVKEHEGNSRSLIFQIFRNDVARRSLLIGCGLQMLQQIIGINTIMYYTALVIRMSGVKDISTILWLSALVAFFNFIPSFIGFILIDKIGRRKLSISSLCCVLLSLITIAITFQVLVSQSEKVTYPSNNYCGKKINCEECVTSSACGFCYIPNAINKSIVLNTSCLATQTHFSKYSSSGWCSQNATHFVSNAIWNYDF-CVSKYSWVIIVGLILYLISFSIGMGPIPWAITSEIYPLWCRSTNMALSTSTNWVFNLIVSLTFLSLTEAITKYGTFWLYSSFAFFGILFIYKFVPETNQRSLEEINDLL 555
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Match: A0A4X2JYT1 (MFS domain-containing protein OS=Vombatus ursinus OX=29139 GN=SLC2A13 PE=3 SV=1) HSP 1 Score: 255.373 bits (651), Expect = 2.614e-73 Identity = 173/563 (30.73%), Postives = 275/563 (48.85%), Query Frame = 3
Query: 87 LFDAGNIEVLYTNQFIHYIT---------FPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIA--------VNLQLFDVRYLKRNQNNNCSNFLACDDC-LNNICEYCQIDENSG---YTCV---NSGAN------CTNKGNYSI------YNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
L D+G++E QF T F +GGF+FGY TG V ++ +V+ G A +S+L G L FGR+ K +LS R ++G+G+GI+S P+YIAE++P +RGR++T+ + +T G F +SVV+ +Y P G +L A+PA+ +G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + + L++K+GRRKL L SL G +I+A V+ Q+ NQN++C+ + +CD C L+ C +C S +CV + AN CTN+ + YNF C W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+ N++ +L F +Y F++Y F G+ IY PET LE++
Sbjct: 65 LGDSGDLERAARRQFQQNETPSFVYVLSVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDMLWQELLVSGTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSVVLSVAQNKETLLSGRVVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTVNTLFITGGQFFASVVDGVFSYL-PKDGWR----YMLGLSAIPAIIQFLGFLFLPESPRWLIQKGQTQKARRILSQIRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVISRMLTYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLIGVWLVEKVGRRKLTLGSLAGTSVALIILALGFLLSAQVSPQISLKPTAPSNQNSSCTKYSSCDGCMLDPGCGFCYKMNKSDVVDSSCVPVNKASANEAAWGRCTNETKFKAEELFWAYNF---CPTPYAWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAGLGLIFIYGCLPETKGRKLEEIE 613
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Match: A0A3Q3WRM5 (Solute carrier family 2 member 13b OS=Mola mola OX=94237 PE=3 SV=1) HSP 1 Score: 254.218 bits (648), Expect = 3.167e-73 Identity = 163/541 (30.13%), Postives = 269/541 (49.72%), Query Frame = 3
Query: 120 TNQFIHYITF-PIIGGFMFGYVTGTVP----------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLK--QIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVR------YLKRNQNNNCSNFLACDDC-LNNICEYCQIDE------------NSGYTCVNSGANCTNK---GNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T FI+ + F +GGF+FGY TG V ++ ++ +V++ G A +SSL GYL GR+ K ++L+ R ++G+G+GI+S P+YIAE++P RG+++TI + +T G F++SV++ ++ S + +L VPAL +G +PES RWLL K R EA V+ +++ Q ++ +I E ++ ++ RIL R+ L++GC LQM QL GIN +MYY+ ++ Q + K +W + + N + + V L+D++GRRKL L SL G ++AV + + + +QN+ CS + +CD C L+ +C +C + + G T + C+N+ + I+ + N C +W++L+G+ILY+ FA GMG +PW V SEIYP W RST A S+G W+ N++ +L F +Y F++Y F + G+ I PET + LE++
Sbjct: 49 TPGFIYLLAFFSALGGFLFGYDTGVVSGAMLLLKKEMNLSSLWQELLVSSTVGAAAVSSLSGGYLNGWLGRRICILLASFIFTIGGIVLSVAPDKEVLLAGRLVVGLGIGIASMTVPVYIAEVSPHHQRGQLVTINSLFITGGQFIASVIDGAFSFLS-----HDSWRYMLGLSIVPALVQFVGFFFLPESPRWLLQKGRSQEARRVLSRIRGGQGVDAEYETIRASIEEEE--------KEAGGDGLVIVRILRYGPTRRALIVGCGLQMFQQLAGINTVMYYSATILQMAGVRDDKQAIWLSAATSATNFVFTLVGVWLVDRVGRRKLTLGSLLGTGVSLSLLAVGFLMSALHSPPVTLHPAGSQNSTCSLYGSCDPCMLDPVCGFCYRENGTRVYDSTCVPVDQGSTSHAAWGRCSNRTEAADSPIWAY-NYCPTSYSWLVLMGLILYLAFFAPGMGTMPWTVNSEIYPLWARSTGNACSSGVNWIFNVLVSLTFLHVAEFLTYYGAFFMYSGFVVLGLLFILGCLPETQGLQLEEIE 575
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Match: F1SHN8 (Solute carrier family 2 member 13 OS=Sus scrofa OX=9823 GN=SLC2A13 PE=3 SV=3) HSP 1 Score: 253.447 bits (646), Expect = 1.376e-72 Identity = 165/544 (30.33%), Postives = 264/544 (48.53%), Query Frame = 3
Query: 120 TNQFIHYIT-FPIIGGFMFGYVTGTVPDVY----------GIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNL----QLFDVRYLKR----NQNNNCSNFLACDDC-LNNICEYCQ-------IDE-----NSGYTCVNSGANCTNKGNYSI------YNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +GGF+FGY TG V ++ +V++ G A +S+L G L FGR+ K +L+ R ++G+G+GI+S P+YIAE++P +RGR++TI + +T G F +SVV+ +Y +L A+PA+ G L +PES RWL+ K + +A ++ +++ + ++ ++ E+ +++ ++CR+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W + F N I + V L++K+GRRKL SL G +I+A+ Q+ LK QN C+ + CD+C L+ C +C ID N T + C N+ + YNF C +W LLG+ILY++ FA GMGP+PW V SEIYP W RST A S+G W+ N++ +L F +Y F++Y F G+ IY PET LE++
Sbjct: 78 TPAFVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGAFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQ-----KDGWRYMLGLAAIPAVIQFFGFLFLPESPRWLIQKGQTQKARRILSQMRG------NQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTLVGVWLVEKVGRRKLTFGSLAGTTVALIILALGFLLSAQVSPPITLKPVAPLGQNTTCTRYSYCDECMLDPDCGFCYKMNKSAIIDSSCVPVNKASTNEAAWGRCENETKFKTEEIFWAYNF---CPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAMGLLFIYGCLPETKGKKLEEIE 607
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a13b (solute carrier family 2 member 13b [Source:ZFIN;Acc:ZDB-GENE-090812-1]) HSP 1 Score: 216.853 bits (551), Expect = 2.070e-63 Identity = 148/464 (31.90%), Postives = 232/464 (50.00%), Query Frame = 3
Query: 243 GGALLSSLPTGYLADRFGRKKTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEA--NVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLF-----DVRYLKRNQNNNCSNFLACDDC-LNNICEYCQIDENSGYTCVNSGANCTNKGNYS-------------IYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS----QIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
GG +LS P K ++L R ++G+G+GI+S P+YIAE++P +RG+++TI + +T G F++SVV+ +Y S +L AVPA+ IG L +PES RWLL K R +A EV+ ++ EN+ E N+ + +E++ +L RIL AR+ LV+GC LQM QL GIN +MYY+ ++ Q + K+ +W + F N + + V L++ + KL L+ G ++AV L V + N CS++ C++C L+ C +C +G T ++S + + N YN+ C +WI++LG++LY+ FA GMGP+PW V SEIYP W RST A S G W+CN++ +L F +Y F++Y + G + PET + LE +
Sbjct: 56 GGVVLSLSP----------NKEVLLVGRLIVGLGIGIASMTVPVYIAEVSPSHLRGQLVTINTLFITGGQFIASVVDGAFSYLS-----HGGWRYMLGLSAVPAVLQFIGFLFLPESPRWLLQKGRSQQAREVLTHIRA---------TENVDEEFNNIKNIIEEEEKESGGGLVLWRILTSAPARRALVVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKMAIWLSAATAFTNFLFTLVGVWLVEH--KTKLYLLLSSGTTVSLSVLAVGFLLSAQASPPVTIHPTSLNTTCSHYGFCENCMLDPACGFCY--RENGSTILSSSCDPVDPANTDEACKFIIHALCIWAYNY---CPTPYSWIVMLGLLLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWICNVLVSLTFLHVAEYLTYYGAFFLYSGLALLGFFFVLGCLPETKGLMLEDIE 488
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:103031966]) HSP 1 Score: 207.608 bits (527), Expect = 6.851e-59 Identity = 140/446 (31.39%), Postives = 229/446 (51.35%), Query Frame = 3
Query: 351 ISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQ---------------NNNCSNFLACDDC-LNNICEYCQIDENS----GYTCV------------NSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS----QIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF*RI 1580
ISS P+YIAE +P +RG+++T+ + +T G F++S+++ +Y +G +L AVPAL G L +PES RWL+ K +A V+ +++ NI E E+I + E+ ++ IL R+L AR+ L++GC LQM QL GIN +MYY+ ++ Q + K+ +W + L N + + + L++K+GRR+L+L S+ G +V+L L +L Q N++C+ +L+C+ C L+ C +C +NS +CV +N T ++S++ + N C +W++LLG+ILY+ FA G+GP+PW V SEIYP W RST A S G W N++ +L F +Y F++Y + ++ G IY PET LE++ + R+
Sbjct: 199 ISSMTVPVYIAEASPPHLRGQLVTVNTLFITAGQFVASLIDGAFSYVQ--HGG---WRYMLGLSAVPALVQFFGFLFLPESPRWLIQKGLTQKARRVLSQIRG--NQNIDEEYESIKSS----IEEEEKDCGGDGPILWRMLTYPPARRALIVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDKLAIWLSSLTALTNFLFTLLGVWLVEKVGRRRLSLGSIIGT-------SVSLCLLAFGFLLSAQHSPPVTIHPTDPSLANSSCTRYLSCEPCMLDPSCGFC-YQQNSTAVFAASCVPVNQASTERAAWGRCSNSTQSADHSLWAY-NFCPTSYSWVVLLGLILYLAFFAPGLGPMPWTVNSEIYPLWARSTGNACSAGVNWTFNVLVSLTFLHLAQYLTYYGAFFLYSSLSLLGFFFIYGCLPETKGRRLEEIESLFESRL 624
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a10 (solute carrier family 2 member 10 [Source:NCBI gene;Acc:103042379]) HSP 1 Score: 129.413 bits (324), Expect = 9.105e-32 Identity = 124/511 (24.27%), Postives = 224/511 (43.84%), Query Frame = 3
Query: 156 IGGFMFGY----VTGTVPDVYGIFHMF------MVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPES-NITEFVENILEANVLIXXXXXXXXXXXXFILCRIL--GDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFD-NPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI----FYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
+GG +FGY ++G + + FH+ +V+ + GA+ +SL G+L DR GR+ +I++S R +G + ISS C ++++E+ P RG ++T+Y+ +T G+ ++ VN L G + P L L+ + +P + L+ + +P+S N+++ E +N ++++ + F + + D + +TL+ G L + Q G +++YA+++FQ N + + L + ++++FVA DK GRR L I CSV+ L L + +L RN + + + + C NN Q+ +N + +N T D P NW++L+ M+ V +F++ GP+ W++ SEI+PA R A + W+ NLI + F S I F+IY + +A IY PET L+ ++ L
Sbjct: 15 LGGLVFGYELGIISGALMQLKAQFHLTCVQQETVVSALLIGAVFASLVGGWLIDRHGRRTSILVSNLLLLCGSLILSSSNSFLMLVVGRLSVGFAICISSMSCCIFVSEMVPSHRRGLMVTLYEAGVTVGILVAYAVNYVLA------GVLEGWRYMFGLAVAPCLAQLVSVWVLPSQNQGLV---------------QLVPDSQNMSDCPEEEPSSNQVLKDHKR-------FTIFHLFQRKDNLRSRTLI-GLGLVLFQQFTGQPNVLFYASTIFQSMGFKNNASAILASLGLGIVKVVATFVAMLCADKAGRRPLL------IGGCSVMA---LGLILIGFLSRNSLLDATRHCSSEPCFNNTM---QVHKNPMELDLMKISNHTTDAGL----LDMPPAMGSYNWLILICMMSVVAAFSVSFGPMTWLILSEIFPAELRGRAFAFTNFFNWVANLIVSFSFLSVIDAIGLSGTFFIYGVIAVAAVAFIYFLLPETKGKSLQDIDQEL 480
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a3b (solute carrier family 2, facilitated glucose transporter member 3-like [Source:NCBI gene;Acc:103028878]) HSP 1 Score: 114.39 bits (285), Expect = 1.400e-26 Identity = 101/435 (23.22%), Postives = 199/435 (45.75%), Query Frame = 3
Query: 222 FMVATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEA---IEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF 1442
F VA + G ++SS+ G L ++FGR K+++LS R +IG+ G+ + P+Y+ E+ P RG T++Q+ + G+ ++ ++ + GS+ P++L A+PA+ + ++ ES R+LL + +E I V+ + ++ E +I E E EA+ L +++K + + + I R+ +++ + + Q GIN + YY+ +F+ ++ + ++ T IN + + V+ L+++ GRR L + L G+ C++++ + LQL V Q + C+ + C+ G V S A+ T I+++ +L + +V SF IG GPIPW + +E++ R +A+ + W+ N + + F
Sbjct: 72 FAVAVFSAGGMVSSVFVGALVNKFGRTKSMLLSNTLALIGGALMGLASACRSYEMVILGRLVIGLFCGLYTGLTPMYVGELAPTAQRGAFGTLHQLAIVIGILIAQILGLEV-----LLGSEYLWPLLLGLTALPAVLQSVMLIFCSESPRYLLINLKQEEEARRILVLLRGQEDVEDDIREMKE---EADKL--------NQEQKVSIPELFRNPIYRQPIIIAIVMNVSQQFSGINAVFYYSTQIFK---SSGVSEPIYATIGTGIINTVFTVVSLFLVERAGRRTLQMFGLGGMAICALVMTIVLQL--VLDPCAPQEDLCAAPVVCN----------------GTVAVTSDASSK--------------TPVISYVAILAVFGFVASFEIGPGPIPWFIATELFAQDARPAAVAVGGCSNWISNFLVAMFF 455
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Match: slc2a3b (solute carrier family 2, facilitated glucose transporter member 3-like [Source:NCBI gene;Acc:103028878]) HSP 1 Score: 102.834 bits (255), Expect = 5.494e-23 Identity = 98/413 (23.73%), Postives = 192/413 (46.49%), Query Frame = 3
Query: 219 MFMVATIA--GGALLSSLPTGYLADRFGRKKTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEA---IEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF 1442
M + T+A GGAL+ LA + +IL R +IG+ G+ + P+Y+ E+ P RG T++Q+ + G+ ++ ++ + GS+ P++L A+PA+ + ++ ES R+LL + +E I V+ + ++ E +I E E EA+ L +++K + + + I R+ +++ + + Q GIN + YY+ +F+ ++ + ++ T IN + + V+ L+++ GRR L + L G+ C++++ + LQL V Q + C+ + C+ G V S A+ T I+++ +L + +V SF IG GPIPW + +E++ R +A+ + W+ N + + F
Sbjct: 49 MLLSNTLALIGGALMG------LASACRSYEMVILG-RLVIGLFCGLYTGLTPMYVGELAPTAQRGAFGTLHQLAIVIGILIAQILGLEV-----LLGSEYLWPLLLGLTALPAVLQSVMLIFCSESPRYLLINLKQEEEARRILVLLRGQEDVEDDIREMKE---EADKL--------NQEQKVSIPELFRNPIYRQPIIIAIVMNVSQQFSGINAVFYYSTQIFK---SSGVSEPIYATIGTGIINTVFTVVSLFLVERAGRRTLQMFGLGGMAICALVMTIVLQL--VLDPCAPQEDLCAAPVVCN----------------GTVAVTSDASSK--------------TPVISYVAILAVFGFVASFEIGPGPIPWFIATELFAQDARPAAVAVGGCSNWISNFLVAMFF 403
BLAST of proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002434.1 (pep scaffold:Pmarinus_7.0:GL479978:1522:11010:-1 gene:ENSPMAG00000002223.1 transcript:ENSPMAT00000002434.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 76.6406 bits (187), Expect = 1.388e-16 Identity = 50/184 (27.17%), Postives = 84/184 (45.65%), Query Frame = 3
Query: 756 FILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNN-----------ICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINW 1274
++L +++ R+ LV+GC LQM QL GIN +MYY+ ++ Q + +W F N I S + L++++GRR+L+LIS+ G V+L L +L +Q + D + N +CE C +D G+ C + +K + + DN T+ W
Sbjct: 2 WVLWKMIKHPPTRRALVVGCGLQMFQQLAGINTVMYYSATILQMAGVADDSTAIWLASATAFTNFIFSALGVWLVERVGRRQLSLISMAGAI-------VSLALLGCAFLLASQTSPPVILHPHDPAVTNSSCMAYSVGRSVCETCMLDPYCGF-CFGMNGSHVDKSSCLPADPDN--TDQATW 175
BLAST of proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: SLC2A9 (solute carrier family 2 member 9 [Source:HGNC Symbol;Acc:HGNC:13446]) HSP 1 Score: 79.7221 bits (195), Expect = 3.551e-16 Identity = 79/317 (24.92%), Postives = 145/317 (45.74%), Query Frame = 3
Query: 222 FMVATIAGGALLSSLPTGYLADRFGRKKT-------------------------IILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRW-LLSKNRIDEAIEVVRKL--KQIPESNITEF-VENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLF-QKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKL------ALISLFGIFSCSVIIAVNLQ 1064
F +A ++ G L+ +L ++ RFGRK T ++ RF++GI GIS + P+Y+AEI+PK +RG + I + G+F V+N G ++ I+ VP L L + +PES R+ LL + + A + +++L +Q + + E E I +A++ + L +L ++ R ++ QL G+N + +YA+S+F Q + I Y+ + T ++++ ++ I+K+GRR L A+ +FG+ + +A+NLQ
Sbjct: 29 FTIAIMSIGGLVGALIMRFMVQRFGRKGTLLLNNALAILAALLMSLCFLAGSWEMLFLGRFVVGIDAGISLSVLPMYLAEISPKNLRGSTGQVSAIFICLGVFTGQVLN-----LKEVLGQESHWSILFGILVVPPLVQLATLPFMPESPRYLLLERQDVKAAEKALQRLLGRQDVQREMVEIQAEGIAQAHISVMS------------LWGLLRERAVRWQVITVAITMACYQLCGVNAIWFYASSIFRQAGIDPAITPYIIISTGGT--EVLAALLSGLAIEKLGRRSLLIVGFGAMAVIFGVLT----VALNLQ 322
BLAST of proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: svopl (SVOP-like [Source:NCBI gene;Acc:492766]) HSP 1 Score: 58.151 bits (139), Expect = 2.385e-9 Identity = 49/169 (28.99%), Postives = 82/169 (48.52%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYA-SPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITE 683
G +LSS P G+LADR+GR K ++L RFL+G G+G S L ++E P RGR++ + Q+ G S++ L Y PT G +I I+ +P+ LLI +PES R+ +S + D+A+ + K+ ++ ++ + +
Sbjct: 96 GFMLSSGPCGFLADRYGRWKVLLLVTIWSSYWSGISSFSPTYGWFVFLRFLMGCGIGGQSQGFVL-MSEFMPSTARGRVLPMSQVFWVLG----SLLEVVLAYLILPTLGWAW---LIRIS-TIPSFVLLIAFKFIPESARYQVSAAKPDKALLTLAKIAKMNKTTLPQ 255
BLAST of proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006105.1 (pep scaffold:Pmarinus_7.0:GL483550:10411:12132:-1 gene:ENSPMAG00000005515.1 transcript:ENSPMAT00000006105.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 48.521 bits (114), Expect = 5.220e-7 Identity = 28/108 (25.93%), Postives = 45/108 (41.67%), Query Frame = 3
Query: 1257 TNYINWILLL---GMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI----FYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T + W+ L G+ F++G GPIPW+V SE++P R + W+ + T + + F FW + + G L PET LE++
Sbjct: 51 TGSLGWLALASMAGLHRRCGRFSLGWGPIPWIVMSEVFPVRWRGVASGVCVAVNWISAFVVTKPTSAAVEWLGFPGAFWFFASVCAAGFVLTIVALPETKGRSLEQIQ 158
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Match: ITR2 (Myo-inositol transporter; member of the sugar transporter superfamily; expressed constitutively; ITR2 has a paralog, ITR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005463]) HSP 1 Score: 108.997 bits (271), Expect = 1.402e-25 Identity = 126/538 (23.42%), Postives = 218/538 (40.52%), Query Frame = 3
Query: 129 FIHYITF-PIIGGFMFGYVTGTVPDV--------------YGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYG---SDTTTPIIL------ITPAVPALFLLIGMLTVPE---SYRWLLSKNR-IDEAIEVVRKLKQ-IPESN-ITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINW--ILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIF----YAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
FI +TF I GFMFGY TG + YG + AT + GAL++S+ G AD FGR+ ++ S R ++G G+GI S PL+I+EI PK+IRGR+ I + LT G ++ A LN+ + + P +L P P +++ G L + ++ +++ ID+ +E + L Q IP N IT+F + E + + + L++GC LQ + Q G N LMY++ ++F+ T K + +++ N + + +A+ IDKIGRR + LI L G+ VI A+ +++ N +A D + +W ++++ +I+Y +A+G+G +PW SE++P R + +T W +L+ F + + F + Y +PE + ++LE++ +L
Sbjct: 108 FIITLTFVASISGFMFGYDTGYISSALISINRDLDNKVLTYGEKELITAAT-SLGALITSVGAGTAADVFGRRPCLMFSNLMFLIGAILQITAHKFWQMAAGRLIMGFGVGIGSLISPLFISEIAPKMIRGRLTVINSLWLTGGQLIAYGCGAGLNHVKNGWRILVGLSLIPTVLQFSFFCFLPDTPRYYVMKGDLKRAKMVLKRSYVNTEDEIIDQKVEELSSLNQSIPGKNPITKFWNMVKELHTVPSNF----------------------RALIIGCGLQAIQQFTGWNSLMYFSGTIFE---TVGFKNSSAVSIIVSGTNFVFTLIAFFCIDKIGRRYILLIGLPGMTVALVICAIAFHFLGIKF------NGADAVVASD-------------------------------------------GFSSWGIVIIVFIIVYAAFYALGIGTVPW-QQSELFPQNVRGVGTSYATATNWAGSLVIASTFLTMLQNITPTGTFSFFAGVACLSTIFCYFCYPELSGLELEEVQTIL 569
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Match: ITR1 (Myo-inositol transporter; member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p; relative distribution to the vacuole increases upon DNA replication stress; ITR1 has a paralog, ITR2, that arose from the whole genome duplication [Source:SGD;Acc:S000002905]) HSP 1 Score: 108.227 bits (269), Expect = 1.893e-25 Identity = 106/379 (27.97%), Postives = 170/379 (44.85%), Query Frame = 3
Query: 75 SIDSLFDAGNIEVLYT-NQ----FIHYITF-PIIGGFMFGYVTGTVPDV--------------YGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVV-RKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRY 1082
I + D + V+ T NQ FI +TF I GFMFGY TG + YG + AT + GAL++S+ G AD FGRK+ ++ S R ++G G+GI S PL+I+EI PK+IRGR+ I + LT G ++ A LNY + + I++ +P + +P++ R+ + K + A EV+ R E I VE ++ N I +K + + + L++GC LQ + Q G N LMY++ ++F+ T K + +++ N I + VA+ IDKIGRR + LI L G+ V+ ++ +++
Sbjct: 62 QIKPVNDEDDTSVMITFNQSLSPFIITLTFVASISGFMFGYDTGYISSALISIGTDLDHKVLTYGEKEIVTAAT-SLGALITSIFAGTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMAVGRLIMGFGVGIGSLIAPLFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGW------RILVGLSLIPTAVQFTCLCFLPDTPRYYVMKGDLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNTIKELHTVPSNL--RALIIGCGLQAIQQFTGWNSLMYFSGTIFE---TVGFKNSSAVSIIVSGTNFIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKF 428
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT13 (Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by non-fermentable carbon sources; induced in low glucose, repressed in high glucose; HXT13 has a paralog, HXT17, that arose from a segmental duplication [Source:SGD;Acc:S000000795]) HSP 1 Score: 106.686 bits (265), Expect = 6.325e-25 Identity = 103/420 (24.52%), Postives = 185/420 (44.05%), Query Frame = 3
Query: 324 RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLS--SVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQI-PESNITEFVENILEANVLIXXXXXXXXXXXXF-ILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLI---FTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
+ + G+G G S CP+ ++EI P +RG ++++YQ+ +TFG+FL SV Y + Y + + L + AL ++IGML VPES R+L+ R +EA + K+ ++ PE + + A VL + +L E ++ F + ++L + L+ G +Q QL G N +Y ++F+ +T+ + + +L +N S+ +A ++DKIGRRK L G+ +C VI A V+ CL Y G + GN +++ Y+ FA P+ ++V +E +P+ +S M++ST WL + FT I + +++ + ++ + PET + LE++
Sbjct: 167 KIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSV------YGTRKYDNTAQWRVPLGLCFLWALIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVL------QRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSI----VLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFAS----IGVK------------------CL--------------YPHGQDGPSSKGAGN----------------AMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQ 518
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT17 (Putative transmembrane polyol transporter; supports growth on and uptake of mannitol and sorbitol with moderate affinity when overexpressed in a strain deleted for hexose family members; minor hexose transport activity when overexpressed in a similar strain; induced by raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose; HXT17 has a paralog, HXT13, that arose from a segmental duplication [Source:SGD;Acc:S000005355]) HSP 1 Score: 104.375 bits (259), Expect = 3.499e-24 Identity = 102/420 (24.29%), Postives = 184/420 (43.81%), Query Frame = 3
Query: 324 RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLS--SVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQI-PESNITEFVENILEANVLIXXXXXXXXXXXXF-ILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKY-VTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLI---FTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
+ + G+G G S CP+ ++EI P +RG ++++YQ+ +TFG+FL SV Y + Y + + L + L ++IGML VPES R+L+ R +EA + K+ ++ PE + + A VL + +L E ++ F + ++L + L+ G +Q QL G N +Y ++F+ +T+ + + +L +N S+ +A ++DKIGRRK L G+ +C VI A V+ CL Y G + GN +++ Y+ FA P+ ++V +E +P+ +S M++ST WL + FT I + +++ + ++ + PET + LE++
Sbjct: 167 KIIYGLGAGGCSVLCPMLLSEIAPTDLRGGLVSLYQLNMTFGIFLGYCSV------YGTRKYDNTAQWRVPLGLCFLWTLIIIIGMLLVPESPRYLIECERHEEARASIAKINKVSPEDPWVLKQADEINAGVLAQRELGEASWKELFSVKTKVL------QRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLTDGFETSI----VLGTVNFFSTIIAVMVVDKIGRRKCLLFGAAGMMACMVIFAS----IGVK------------------CL--------------YPHGQDGPSSKGAGN----------------AMIVFTCFYIFCFATTWAPVAYIVVAESFPSKVKSRAMSISTACNWLWQFLIGFFTPFITGSIHFYYGYVFVGCLVAMFLYVFFFLPETIGLSLEEIQ 518
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Match: HXT3 (Low affinity glucose transporter of the major facilitator superfamily; expression is induced in low or high glucose conditions; HXT3 has a paralog, HXT5, that arose from the whole genome duplication [Source:SGD;Acc:S000002753]) HSP 1 Score: 104.375 bits (259), Expect = 3.540e-24 Identity = 122/519 (23.51%), Postives = 197/519 (37.96%), Query Frame = 3
Query: 159 GGFMFGYVTGTVPDVYG---IFHMFMVATIAGGALLSSLPTG------------------YLADRFGRKKTIILS-----------------------*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQI-PESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTF--INLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICG-----IALIYKYFPETNQIDLEKMN 1559
GGF+FG+ TGT+ F + G LS + TG L D +GRK +I+ R + G+G+G + P+ I+E+ PK +RG +++ YQ+ +T G+FL N+ + Y + + L ALF++ GM VPES R+L+ +IDEA + K+ ++ P+ + ++EA+V + F G K +MG +Q L QL G N YY ++F N + + F + F +N S+ + +D+ GRR L G+ C V+ A V L N N S+ NC +++ Y+ FA PI +VV SE +P +S M+++T A WL F + FF+ Y + G ++ + PET + LE++N
Sbjct: 72 GGFVFGWDTGTISGFVAQTDFLRRFGMKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCT----NFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFT-----GKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVF-----NAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYAS----VGVTRLWPNGEGNGSS--------------------------KGAGNC----------------------MIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWG--FLIGFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVN 522
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO46902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNS4]) HSP 1 Score: 226.868 bits (577), Expect = 1.370e-67 Identity = 164/532 (30.83%), Postives = 261/532 (49.06%), Query Frame = 3
Query: 147 FPIIGGFMFGYVTGTVP-------DVYGI---FHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQN-------------NNCSNFLACDDCLN-NICEYCQIDENSGY----TCVNSGANCTN------KGNYSIYNFDN-PCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFY----AIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
F IGGF+FGY TG V +V+ + +H +V+ G A++ ++ G L D GRK K ++L R +IG+G+G +S P+Y+AE P +RG+++T+ + +T G F++SVV+ Y +L AVP++ + G + +PES RWL+SK + EA + K++ + V+ LEA + E+KE+ +L RIL R+ L++GC LQ + QL GIN +MYY+ ++ N K +W + F N + + V L+++IGRRKL L SL G VI+++ L L YL N +C+N C DC+N C YC ++ G +CV + + T S Y++ C + W+ LG+++Y+ +FA GMGP+PW + SE+YP W RST A ST W+CNL+ ++ F S + + FW+Y + G + + PET LE+++
Sbjct: 11 FAAIGGFLFGYDTGVVSGAMILISEVFHLSDFWHELIVSGTIGTAIVGAVLGGILNDSLGRKPVLVLCSGVFTAGAVVMGVAGTKHVLLVGRLVIGLGIGGASMTVPIYVAEAAPSSMRGKLVTLNNLFITGGQFIASVVDGIF-----AYDRQNGWRFMLGLAAVPSIIMFFGCVILPESPRWLISKCKYAEARAALCKIRGRTD------VDRELEA--VRRTCKVERKERSGQVLIRILRFPNTRRALLVGCMLQAIQQLCGINTVMYYSATIILMSGIGNSKTSIWLAAAIAFGNTLFTIVGIFLVERIGRRKLLLGSLAG-----VILSLFL-LGGAFYLAMQHNPKVSTAETINPVFTHCTNQTTCMDCVNVRNCGYCYSTDSDGSILQGSCVYANTSTTKAWYGRCHTQSSQYSWRYIACPSKYAWMAFLGLVIYIATFAPGMGPMPWTLNSEMYPLWARSTGNACSTAVNWICNLVISMTFLSLMGWITRPGAFWLYGCIAVAGWVFFFVFVPETKGKTLEELD 523
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO32615 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUJ6]) HSP 1 Score: 109.383 bits (272), Expect = 9.503e-26 Identity = 107/443 (24.15%), Postives = 192/443 (43.34%), Query Frame = 3
Query: 252 LLSSLP--TGYLADRFGRKKTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYA-SPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQI----FYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
+L+S+P +G+L FG+ ++ + RF+ G+G+G++S P+YI+E RG + +I Q+ +T G+ +S + ++ S GS PA L++ M +PE+ RWL++K + A + + L+ P+ +I + + I +A++ + ++F L + R L+ SL Q GIN M+Y ++FQK K L+ + ++S ++ LID+ GRR L +++ G+ ++C C Y I N G T V+ I W+ + + +Y++ FA+G GP W++ SEI+P R T ++T W C+ + T F + I F + AF + +Y + PET LE++
Sbjct: 74 ILTSVPFCSGWLLIGFGKNAAMLNAGRFMSGLGVGMASLNVPVYISETASFSNRGAMGSINQLGITAGILISYAIGYAFDWRWSAVAGS------------FPAALLVVLMAFMPETARWLIAKKKETRARKTLLWLRG-PDYDIDKELCEI-KASI--------DTQNQRFSLKEFKNPSLLRPFLI-SMSLHFFQQFSGINAFMFYCATIFQK---AGFKDPTGVPILIGAVQFVASAISLALIDRGGRRFLLIVAGVGMS-----------------------------ISCFTC----AVYFFITVNFGMTEVD-----------------------IAWLSVTSVAVYIVGFALGWGPCTWLIMSEIFPVRARGTATGIATFFNWFCSFVVTKTFSALIDGLTEAGTFCFFGAFVFASVLFVYFFVPETKGKTLEEIQ 434
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO42861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0E6]) HSP 1 Score: 101.293 bits (251), Expect = 5.321e-23 Identity = 105/506 (20.75%), Postives = 198/506 (39.13%), Query Frame = 3
Query: 150 PIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPT----------GYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFF----SQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
P+ GF GY + + D+ + T++ G+ SSL T G+ + FGRK TI+ RF+ G+ +G+ S P+YIAEI+ +RG + ++ Q+ +T GL L+ + L + + + A+ L++ M VPE+ RW LS R +A++ + + PE+++ E I EA + + + + C K L + +L Q GIN +++ + S+F + + K + ++ + + + +A ++DK GR+ L + G+ + + +L Y+ Q + ++I I+W+ + ++++ + FA+ GP+PW+V SEI+P R ++ST W T F + +W Y + G + + PET LE++
Sbjct: 12 PLSFGFCLGYSSSALEDLIAESKESVKLTVSQGSWFSSLVTLGAILGAPLGGWTLEYFGRKGTIMACAVPFEVGWMLIAYANSHYMLYIGRFITGLAVGMVSLTVPVYIAEISSPSLRGMLGSVNQLAVTMGLLLAYSMGVVLKWR-----------WLACSGAIFPALLVVLMFFVPETPRWSLSHKRRRDALDAMMWFRG-PEADVEEECYRI-EATM----------DNTQSMSCAEFCRPAIMKPLFISIALMFFQQFCGINAILFNSASIFHQAGFQDSKA---VSVIIGAVQFVGTGIACLVVDKAGRKLLLWTTALGMTVSLIALGFYFEL----YIPTTQEQPTPTPALLESIHHSI-----------------------------------PAGKISWLAITSIVVFNLVFALAWGPVPWLVMSEIFPLQARGIASSISTLCNWSLAFAVTKTFVNIEDAITIQGTYWFYGGLSFLGFLFVLMFVPETKGKTLEQIE 452
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO42862 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0E7]) HSP 1 Score: 98.9821 bits (245), Expect = 3.730e-22 Identity = 103/415 (24.82%), Postives = 187/415 (45.06%), Query Frame = 3
Query: 246 GALLSSLPTGYLADRFGRKKTIILS*----------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITE---FVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWL 1415
GAL SS G++ DRFGRK T++LS RF+ G+G+G+ + P YIAEI+ +RG + +++Q+ +T GL L+ + + + I L +P + +++ M VPE+ RW L N A++ + + P +I + +E L+ + +K L I R L++G L + QL G +++ S+F+ +N K + LL ++ +A ++DKIGRR L L+S+ + C I + F++ + N + L+N + V+SG I++ ++YI+W+ + +I++ ++F++ GP+PW+V SEI+P R +++T A W+
Sbjct: 93 GALASSPLGGFIVDRFGRKATLMLSAVPSELGWLLIAFAQNHAMMYAGRFIAGLGIGLIAVAVPTYIAEISSAKLRGALGSVHQLSITAGLLLAYIFGVFFKWRA----------IALAGAIIPGVLVVL-MFCVPETPRWFLGHNERGAALKSLEWFRG-PNGDIEQECFEIECTLDTH-------------EKLTFSEFLRPAI-RNPLIVGVGLMVFQQLCGAIVVVFNCASIFKSAGFDNSKAV---SILLGASQFGANIIACLIMDKIGRRIL-LMSM-ALLMCISHIGLG-TYFELIIIPSNSS------------LHN-------------STVHSGL---------IHSIP---SSYISWLAITCIIVFNVAFSLAWGPVPWLVMSEIFPLRARGVAGSIATSAAWV 438
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Match: EDO35120 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMF8]) HSP 1 Score: 90.5077 bits (223), Expect = 2.309e-19 Identity = 72/293 (24.57%), Postives = 141/293 (48.12%), Query Frame = 3
Query: 228 VATIAGGALLSSLPTGYLADRFGRKKTIILS*-------------------------RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIF 1031
VA A G ++ +L A+RFGRK++++ + RF+IGI G+++ P+Y++E+ P +RG + T+ Q + GL + + G+ +L +PA+F L+ + P S R+LL + +D+ ++ V L+++ ++ + E+I E + + + + + R + + L++GC + M QL GIN ++YY+ S+F+K ++ T + + L+ + +A +L++ +GRR L LI L G+F
Sbjct: 79 VAIFAIGGMIGALAGPLFANRFGRKRSLLANNGLAIVGALLMFLSYFAKTSPLLTVGRFVIGINCGMNTAIAPIYLSELAPIHLRGSLGTLNQFGIVSGLLVGFIFG-----LKQVLGTSKGWQYLLGFSILPAVFQLVTLPWCPNSPRYLLIE--LDQELQAVEALRKLRATD--DVTEDINEMKIERDREATTEHVSVLQLFVR----RDLQMPLLIGCVMMMAQQLGGINAVLYYSTSIFEKVGVPESRVA---TTGIGVVALVFTAIAVRLVEVLGRRTLMLIGLGGMF 355
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a13b (proton myo-inositol cotransporter [Source:NCBI gene;Acc:101158939]) HSP 1 Score: 232.261 bits (591), Expect = 1.788e-68 Identity = 160/546 (29.30%), Postives = 266/546 (48.72%), Query Frame = 3
Query: 120 TNQFIHYITF-PIIGGFMFGYVTGTVP----------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDD-----CLNNICEYCQIDENSGYTCVNSG---------------------ANCTNKGN---YSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +GGF+FGY TG V ++ ++ +V++ G A +S+L G+L GR+ K ++L R ++G+G+GI+S P+YIAE++P +RG+++T+ + +T G F++S+V+ +Y S + +L +PA+ +G + +PES RWLL K + EA++V+R ++ + N+ E ++I +AN+ E+ +++ +L R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + K +W + N + + V L++++GRRKL L SL G ++L L V +L Q++ D L CE C +D + G+ +G C NK I+ + N C +WI+L+G+ LY+ FA GMGP+PW V SEIYP W RST A S G W+ N++ +L F +Y F++Y G+ + PET + LE M
Sbjct: 31 TTGFVYVLAFFSALGGFLFGYDTGVVSGAMLLLKKRMNLSALWQELLVSSTVGAAAVSALAGGFLNGWLGRRICILLASLIFSVGGVMLALAPDKVVLLVGRIIVGLGIGIASMTVPVYIAEVSPPHLRGQLVTVNALFITGGQFIASMVDGAFSYLS-----EDGWRYMLGLSVLPAVLQFLGFIFLPESPRWLLQKGQNQEALQVLRWIRG--DQNVEEEYDSI-KANI---EEEEKEVGAGGVVLLRMLSHGPTRRALIVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKEAIWLAAATSATNFVFTLVGVWLVERVGRRKLTLGSLLGT-------GLSLALLAVGFLLSAQSSPPVTLHPVDPNNSTYRLYGSCEPCMLDPDCGFCFRENGTKVFESSCVPVHQASIDHAAWGRCYNKTEDIKSPIWAY-NYCPTSYSWIVLMGLFLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWIFNVLVSLTFLHVAEYLTYYGAFFLYTGLVFLGLLFVLGCLPETRGLQLEDME 557
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a13b (proton myo-inositol cotransporter [Source:NCBI gene;Acc:101158939]) HSP 1 Score: 231.876 bits (590), Expect = 1.989e-68 Identity = 160/546 (29.30%), Postives = 266/546 (48.72%), Query Frame = 3
Query: 120 TNQFIHYITF-PIIGGFMFGYVTGTVP----------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDD-----CLNNICEYCQIDENSGYTCVNSG---------------------ANCTNKGN---YSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQ----IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
T F++ + F +GGF+FGY TG V ++ ++ +V++ G A +S+L G+L GR+ K ++L R ++G+G+GI+S P+YIAE++P +RG+++T+ + +T G F++S+V+ +Y S + +L +PA+ +G + +PES RWLL K + EA++V+R ++ + N+ E ++I +AN+ E+ +++ +L R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + K +W + N + + V L++++GRRKL L SL G ++L L V +L Q++ D L CE C +D + G+ +G C NK I+ + N C +WI+L+G+ LY+ FA GMGP+PW V SEIYP W RST A S G W+ N++ +L F +Y F++Y G+ + PET + LE M
Sbjct: 31 TTGFVYVLAFFSALGGFLFGYDTGVVSGAMLLLKKRMNLSALWQELLVSSTVGAAAVSALAGGFLNGWLGRRICILLASLIFSVGGVMLALAPDKVVLLVGRIIVGLGIGIASMTVPVYIAEVSPPHLRGQLVTVNALFITGGQFIASMVDGAFSYLS-----EDGWRYMLGLSVLPAVLQFLGFIFLPESPRWLLQKGQNQEALQVLRWIRG--DQNVEEEYDSI-KANI---EEEEKEVGAGGVVLLRMLSHGPTRRALIVGCGLQMFQQLSGINTVMYYSATILQMAGVRDDKEAIWLAAATSATNFVFTLVGVWLVERVGRRKLTLGSLLGT-------GLSLALLAVGFLLSAQSSPPVTLHPVDPNNSTYRLYGSCEPCMLDPDCGFCFRENGTKVFESSCVPVHQASIDHAAWGRCYNKTEDIKSPIWAY-NYCPTSYSWIVLMGLFLYLAFFAPGMGPMPWTVNSEIYPLWARSTGNACSAGVNWIFNVLVSLTFLHVAEYLTYYGAFFLYTGLVFLGLLFVLGCLPETRGLQLEDME 557
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:101157657]) HSP 1 Score: 192.971 bits (489), Expect = 9.691e-54 Identity = 142/526 (27.00%), Postives = 246/526 (46.77%), Query Frame = 3
Query: 99 GNIEVLYTNQFIHYIT---------FPIIGGFMFGYVTGTVP----------DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRK----------------------KTIILS*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLK---------RNQNNNCSNFLACDDC-LNNICEYCQIDENSGY---TCVN---------SGANCTN-----KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFW 1472
G +E QF +T F +GGF++GY TG + + ++ ++++ A LS+L G+L FGR+ K +L+ R ++G+GLGI + P+YIAE +P +RG+++T+ + +T G F +S+++ +Y +L +PA+ +G L +PES RWL+ + +A V+ +++ NI E ++I + E+ ++ ++ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W L T N + + + L++K+GRRKL L S+ G ++AV L ++ N+ CS + C+ C L+ C +C +S +CV + C+N Y YN+ C W++LLG+++Y +FA GMGP+PW + SEIYP W RST A + G W N++ ++ F Y ++
Sbjct: 65 GELERAARKQFQQDVTPGFVYVLAAFSALGGFLYGYDTGVISGAMLLLKRELQLSALWQELLISSTVAAAALSALLGGFLNGLFGRRVCVLLASFCFTVGGIVLSAAPGKEALLAGRIIVGVGLGIVTMTVPVYIAEASPPHLRGQLVTVNTLFITGGQFTASLIDGAFSYLQ-----HDGWRYMLGLSVIPAVLQFLGFLFLPESPRWLIQRGLTQKARRVLSQIRG--NQNIDEEYDSIKNS----IEEEEKDSGGDGPVVWRMLTYPPTRRALLVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDRLAIWLAGLATLTNFLFTLLGVWLVEKVGRRKLTLGSILGTTLSLSLLAVGF-LMSAQHSPPVTFRPLDPAMANSTCSKYRLCEPCMLDPSCGFCYRRNSSALLATSCVAVNKASTEHAAWGRCSNSTLMKDQTYWAYNY---CPTSYFWLVLLGLVMYFAAFAPGMGPMPWTINSEIYPLWARSTGNACAAGVNWTFNILVSVTFLHLAQYLTYY 575
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Match: SLC2A13 (solute carrier family 2 member 13 [Source:NCBI gene;Acc:101157657]) HSP 1 Score: 185.652 bits (470), Expect = 2.192e-52 Identity = 122/427 (28.57%), Postives = 210/427 (49.18%), Query Frame = 3
Query: 369 PLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQL-------FDVRYLKRN-QNNNCSNFLACDDC-LNNICEYCQIDENSGY---TCVN---------SGANCTN-----KGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS----QIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMN 1559
P+YIAE +P +RG+++T+ + +T G F +S+++ +Y +L +PA+ +G L +PES RWL+ + +A V+ +++ NI E ++I + E+ ++ ++ R+L R+ L++GC LQM QL GIN +MYY+ ++ Q + ++ +W L T N + + + L++K+GRRKL L S+ G ++AV + R L N+ CS + C+ C L+ C +C +S +CV + C+N Y YN+ C W++LLG+++Y +FA GMGP+PW + SEIYP W RST A + G W N++ ++ F +Y +F++Y + + G +Y PET LE++
Sbjct: 4 PVYIAEASPPHLRGQLVTVNTLFITGGQFTASLIDGAFSYLQ-----HDGWRYMLGLSVIPAVLQFLGFLFLPESPRWLIQRGLTQKARRVLSQIRG--NQNIDEEYDSIKNS----IEEEEKDSGGDGPVVWRMLTYPPTRRALLVGCGLQMFQQLSGINTVMYYSATILQMSGVRDDRLAIWLAGLATLTNFLFTLLGVWLVEKVGRRKLTLGSILGTTLSLSLLAVGFLMSAQHSPPVTFRPLDPAMANSTCSKYRLCEPCMLDPSCGFCYRRNSSALLATSCVAVNKASTEHAAWGRCSNSTLMKDQTYWAYNY---CPTSYFWLVLLGLVMYFAAFAPGMGPMPWTINSEIYPLWARSTGNACAAGVNWTFNILVSVTFLHLAQYLTYYGVFFLYSSLALLGFVFVYGCLPETKARRLEEIE 416
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Match: slc2a8 (solute carrier family 2, facilitated glucose transporter member 8 [Source:NCBI gene;Acc:101171341]) HSP 1 Score: 105.145 bits (261), Expect = 9.273e-24 Identity = 94/418 (22.49%), Postives = 174/418 (41.63%), Query Frame = 3
Query: 324 RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIF----FSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYV 1565
R L G+ G++S PLYI+E+ + +RG + + Q+ + G+ L + +++ + I +VP +++ M +PE+ R+LLS+ + EA E +R L+ P++ T F + L+ D K L++G L + Q+ GIN +M+YA ++F++ + + ++ I ++ + VA ++DK GR+ L +IS + +V + V L G+ T+ + + D ++W+ L M +++ FAIG GPIPW++ SEI+PA R A+ + W + T F S FW++ + + I + PET LE++ +
Sbjct: 124 RVLTGMASGVTSLVVPLYISEMAHEKVRGTLGSCVQLMVVLGILLVYFLGLFMDWR-----------WLAICCSVPPTLMMVLMCFMPETPRFLLSQGKRREAEEALRFLRG-PDAPGTSFHISDLK-------------------------DPGVYKPLIIGVMLMVFQQMTGINAIMFYAENIFEQAHFEESDLA---SVIVGLIQVVFTAVAALIMDKAGRKILLIISGVAMTISTVALGVYFHLMS----------------------------------------KLGSAVTDSTSVTAEQPD------LSWLALASMAVFISGFAIGWGPIPWLIMSEIFPAKARGFASAMVVLSNWGMAFVVTKTFQDMLMSLTSAGTFWLFSSTCVVNILFTVFFIPETKGKTLEQIEAI 455
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056331.1 (SMESG000056331.1) HSP 1 Score: 657.136 bits (1694), Expect = 0.000e+0 Identity = 349/527 (66.22%), Postives = 412/527 (78.18%), Query Frame = 3
Query: 60 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVP--DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*RF---------------------LIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF 1571
MNF+ S+DSL+D IEV +T Q+IH+I FP+IGGFMFG+VTG+V +F + + GAL +SL TG L DRFGRKK II+S F L+GIG+G+ TCCPLYIAE+TPK+IRGR+IT+YQ+ +TFG+ L+S+V A++ +Y I+L TP +PA+ +LIGMLTV ESYRWLL+KNR DEA EV+RKLKQ+ ES+I EFV+ ILEAN++IEE+ +++ F+L RIL +KIARK+L+ GC +Q++ Q+ GIN ++Y + LFQ + + + LWF L+ F N I SFVAYKLIDKIGRRKLALISLFGI VIIAVNLQL VR L NQNNNCSNFL+CDDC+NN CEYCQIDE+SGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS+IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF
Sbjct: 1 MNFDISLDSLYDINKIEVYFTRQYIHHIIFPMIGGFMFGHVTGSVSINKTNDLFFYLNLPILILGALFASLLTGSLVDRFGRKKMIIISCVFCIIGSLITLSPGIAPKYITNVLVGIGIGVICTCCPLYIAEMTPKLIRGRVITLYQVSITFGILLASIVKASICRKDESY------IIVLTTPLIPAIIVLIGMLTVSESYRWLLTKNRKDEAKEVIRKLKQLQESSIEEFVKIILEANIVIEEENSQKR----FMLFRILRNKIARKSLLFGCYIQIIGQIAGINAILYNSPLLFQYFNNMSYERALWFGSLIYFFNFIPSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVYVRRL--NQNNNCSNFLSCDDCINNYCEYCQIDESSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSRIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF 515
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056331.1 (SMESG000056331.1) HSP 1 Score: 616.305 bits (1588), Expect = 0.000e+0 Identity = 331/496 (66.73%), Postives = 388/496 (78.23%), Query Frame = 3
Query: 153 IIGGFMFGYVTGTVP--DVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS*RF---------------------LIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILITPAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIXXXXXXXXXXXXFILCRILGDKIARKTLVMGCSLQMLAQLIGINGLMYYANSLFQKYVTNNIKIYLWFTPLLTFINLISSFVAYKLIDKIGRRKLALISLFGIFSCSVIIAVNLQLFDVRYLKRNQNNNCSNFLACDDCLNNICEYCQIDENSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF 1571
+IGGFMFG+VTG+V +F + + GAL +SL TG L DRFGRKK II+S F L+GIG+G+ TCCPLYIAE+TPK+IRGR+IT+YQ+ +TFG+ L+S+V A++ +Y I+L TP +PA+ +LIGMLTV ESYRWLL+KNR DEA EV+RKLKQ+ ES+I EFV+ ILEAN++IEE+ +++ F+L RIL +KIARK+L+ GC +Q++ Q+ GIN ++Y + LFQ + + + LWF L+ F N I SFVAYKLIDKIGRRKLALISLFGI VIIAVNLQL VR L NQNNNCSNFL+CDDC+NN CEYCQIDE+SGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFS+IFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF
Sbjct: 1 MIGGFMFGHVTGSVSINKTNDLFFYLNLPILILGALFASLLTGSLVDRFGRKKMIIISCVFCIIGSLITLSPGIAPKYITNVLVGIGIGVICTCCPLYIAEMTPKLIRGRVITLYQVSITFGILLASIVKASICRKDESY------IIVLTTPLIPAIIVLIGMLTVSESYRWLLTKNRKDEAKEVIRKLKQLQESSIEEFVKIILEANIVIEEENSQKR----FMLFRILRNKIARKSLLFGCYIQIIGQIAGINAILYNSPLLFQYFNNMSYERALWFGSLIYFFNFIPSFVAYKLIDKIGRRKLALISLFGIIFSLVIIAVNLQLVYVRRL--NQNNNCSNFLSCDDCINNYCEYCQIDESSGYTCVNSGANCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSRIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVLF 484
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056326.1 (SMESG000056326.1) HSP 1 Score: 266.929 bits (681), Expect = 3.037e-87 Identity = 136/167 (81.44%), Postives = 141/167 (84.43%), Query Frame = 3
Query: 60 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTVPDVYGIFHMFMVATIAGGALLSSLPTGYLADRFGRKKTIILS--------------------*RFLIGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLSSVVNATLNYASPT 500
MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGT+PDV G HM +VAT+ GGALLSSLPTGYLADRFGRKKTIILS RFL+GIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFL+SVVNATLNYASPT
Sbjct: 1 MNFEYSIDSLFDAGNIEVLYTNQFIHYITFPIIGGFMFGYVTGTIPDVNGTSHMLIVATVVGGALLSSLPTGYLADRFGRKKTIILSCLFYIVGSLLSFNYLVEIAVGRFLVGIGLGISSTCCPLYIAEITPKVIRGRIITIYQICLTFGLFLASVVNATLNYASPT 167
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056325.1 (SMESG000056325.1) HSP 1 Score: 190.66 bits (483), Expect = 1.084e-56 Identity = 89/121 (73.55%), Postives = 98/121 (80.99%), Query Frame = 3
Query: 1206 NCTNKGNYSIYNFDNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTGAMWLCNLIFTLIFFSQIFYAIFWIYCAFTICGIALIYKYFPETNQIDLEKMNYVL 1568
N KGNYSIYNF NPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALST A W N T+ F+ Y FWIY AFT+CGIALIY+ FPE NQ ++E++ +VL
Sbjct: 135 NVLEKGNYSIYNFHNPCTNYINWILLLGMILYVISFAIGMGPIPWVVTSEIYPAWCRSTNMALSTTANWFFNFSVTMTVFAIGLYETFWIYSAFTLCGIALIYRNFPEMNQANMEEILHVL 255 HSP 2 Score: 100.138 bits (248), Expect = 1.912e-23 Identity = 49/49 (100.00%), Postives = 49/49 (100.00%), Query Frame = 3
Query: 573 MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 719
MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI
Sbjct: 1 MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 49
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Match: SMESG000056221.1 (SMESG000056221.1) HSP 1 Score: 95.9005 bits (237), Expect = 3.659e-21 Identity = 70/220 (31.82%), Postives = 104/220 (47.27%), Query Frame = 3
Query: 168 MFGYVTGTVPD----VYGIFHMFMVAT---IAG---GALLSSLPTGYLADRFGRKKT----------------------IILS*RFLIGIGLGISSTCCPLYIAEITPKVIR---GRIITIYQICLTFGLFLSSVVNATLNYASPTYGSDTTTPIILIT-PAVPALFLLIGMLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLI 719
MFGY TG + + FH+ ++ ++G A LSSL TG+L+D GRKKT +++ R +G G +AE+T IR + T+ Q ++ S +N + DT I ++ A+P+ IGMLTVPESYRWLLSKN++DEA ++ Q+PE ITE+++ I+ AN I
Sbjct: 1 MFGYDTGVISGALLLIRDHFHLSTISQEIVVSGTVLSAALSSLITGWLSDWIGRKKTIIISCICFIIGSIIMGISQNFIMLVFGRIFVGFG-----------VAEVTGVRIRDIWSVLETVNQERVSSDSEEDSKINEDSQITKEMFTDDTILHIYMLGGAAIPSFIEFIGMLTVPESYRWLLSKNKVDEARTIIVNQGQVPEERITEYIDEIVRANQQI 209 The following BLAST results are available for this feature:
BLAST of proton myo-inositol cotransporter vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of proton myo-inositol cotransporter vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of proton myo-inositol cotransporter vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025913 ID=SMED30025913|Name=proton myo-inositol cotransporter|organism=Schmidtea mediterranea sexual|type=transcript|length=1606bpback to top protein sequence of SMED30025913-orf-1 >SMED30025913-orf-1 ID=SMED30025913-orf-1|Name=SMED30025913-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=334bp MLTVPESYRWLLSKNRIDEAIEVVRKLKQIPESNITEFVENILEANVLIEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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