Leukotriene A(4) hydrolase

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     +DF R+ + G+  L +++       L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I+KF QKV I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ S+  +GE H F +LV  L + DPD ++S VPYEKG  LLF+LE + G  ++ L +LK Y E + YKS+TTD+WK F Y Y  DK ++    L+ VDW  W Y     P+         +A   L+ +WI    +     + +D KDL         HQ   FL      + A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V+ + +++ +MHP+TA
Sbjct:    9 SLASPASVCR-----TKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGE-RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRK----IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV----LNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDL-------SSHQLNEFLA--QTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKASMHPVTA 601          

Query:  218 LQLKNLTKKQ--------------ADLK-LDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWI-----NLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            L  +NL+K+Q              A LK LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I+KF QKV I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ S+  +GE H F +LV  L + DPD ++S VPYEKG  LLF+LE + G  ++ L +LK Y E + YKS+TTD+WK F Y Y  DK ++    L+ VDW  W Y     P+         +A   L+ +WI     +LN   + +D KDL         HQ   FL      + A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V+ + +++ +MHP+TA
Sbjct:    2 LPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGE-RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRK----IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV----LNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLN-SFNATDLKDL-------SSHQLNEFLA--QTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKASMHPVTA 577          

Query:  218 LQLKNLTKKQ--------------ADLK-LDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWI-----NLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHS 1657
            L  +NL+K+Q              A LK LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I+KF QKV I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ S+  +GE H F +LV  L + DPD ++S VPYEKG  LLF+LE + G  ++ L +LK Y E + YKS+TTD+WK F Y Y  DK ++    L+ VDW  W Y     P+         +A   L+ +WI     +LN   + +D KDL         HQ   FL        A LHS
Sbjct:    2 LPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGE-RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRK----IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV----LNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLN-SFNATDLKDL-------SSHQLNEFLAQTLQRMAAALHS 493          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFD-------RKLIEGSVNLQLKNL-TKKQADLKLDT-KYLDIKKVSVK----GTE------TRFDIVDCKIEALGSCLKIPIGI-SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKI------PVDHVLKRDHGDASERLADKWINLNPEISDSDQKDL-LLEYESFLPHQKYYFLQVLND-FKEAKLHSKVIETMGNLY-QYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMH 1909
            D  S +N   +   HL  D   +F         + + G+  L L+ L  +  A+L+LD+   L++   +++    G+E        F            C+  P    + E+  V + Y        + WL PE T GKK P++++Q QA+  R+ FPC D+P VK  YSA ++ P+ F  +MSA   E   K G +    F+    I SYL+A+  G+L   ++  RS VW+EP +++ A  E+    E  L+  E + G YVWG YDLL +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI+HSW GNLVTN  W +FWLNEG T Y +R I    + +     L  + G A L++ ++  GE +  N+L V +    DPDD+++  PYEKG   + +L ++ G +DQ   +LK Y   +K++S+  D++  F+ +Y  + +      +   ++ +W     W        P D ++K      +E LA  W         +++ D+  +E  +  P + Y  +  L+   +++ L    ++ +G+ Y   + + N+E+   W  + ++++H     ++ +FL++QG+ KYT P+Y  +    ++  + L  + F    + +H
Sbjct:   24 DVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTY-RVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWE---KRGPNKFF-FQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT-CLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMK-----PAEELAQLWA--------AEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGG-SEVAQTLAKETFASTASQLH 634          

Query:  416 TTANCTALQ----------WLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYM 1384
            T  +CT+L           WL PE T GKK P++++Q QA+  R+ FPC D+P VK  YSA ++ P+ F  +MSA   E   K G +    F+    I SYL+A+  G+L   ++  RS VW+EP +++ A  E+    E  L+  E + G YVWG YDLL +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI+HSW GNLVTN  W +FWLNEG T Y +R I    + +     L  + G A L++ ++  GE +  N+L V +    DPDD+++  PYEKG   + +L ++ G +DQ   +LK Y   +K++S+  D++  F+ +Y 
Sbjct:    2 TCCSCTSLSALLDFWAEVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWE---KRGPNKFF-FQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT-CLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYF 332          

Query:  113 NDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEK----FSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE--LQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLE-YESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
             DP S AN  +   EH    W + F  K+I G   L+ + LT     L LD + L I+ VS+ G +  F I        GS + + +    +K      V + Y T+ + TALQW+  E T  K+ PYLFSQCQAIHARS+ PC D+P VKSTY A+V  P     LMSAI  +    + +     ++Q V I SYL+AIV G L  + +S+R  VW+EP +V+KA  EFA+TE++L+ AE I G+Y+WG YD++ LPPSFP+GGMENPCLTF+TPTL+ GD+SLV V+AHEI HSW+GNLVTN +WE FWLNEG T +IER I  +   SE  R  +   G     +      +   H+F +L+      DPD +FS VPYEKGS LLF+LE   G  ++   +LK Y + + ++++ + +WK   YKY  D++ +    LD V++  WF G    P      +   +A E L  KW+  +    +S   D+  E Y +  P Q+   L  L        H K ++ +  LY+   S NSE+L  W+ LCI+S     I +  DF+NSQGRLK+ +PIYR+LA WP  + K   V  +LK  + MHPITA+ I
Sbjct:   11 RDPCSAANINEITVEHTAIKWTVSFQLKMIIGQATLRCRCLTDA-TKLVLDVRDLSIRSVSINGVDCDFRIAPNVYTFFGSKMSVYLPPQFQKAGTILQVTVAYGTSPDATALQWMKKEQTADKRMPYLFSQCQAIHARSIVPCMDTPSVKSTYEAEVTVPTGMTCLMSAI-GQGSKGDDDTTTFFYKQPVAIPSYLIAIVVGCLEKRDISDRCAVWAEPSVVDKAHWEFAETEDILASAEEIAGKYIWGRYDMVCLPPSFPFGGMENPCLTFLTPTLIAGDRSLVSVIAHEIAHSWSGNLVTNSSWEHFWLNEGFTMFIERKICGRLV-SEDYRQFMAFNGWTNSLIPAVYEQFTPTHQFTKLIQDHTNVDPDVAFSCVPYEKGSALLFYLEQKLGGSEIFEAYLKDYLKTFAHQAIDSWQWKDHLYKYFADQKEV----LDTVNFDLWFNGVGMPPEKPNYGQSMVEACEVLLKKWLAAD----ESTVGDITSEDYYAMQPLQQIELLSQLWQHDPPIEHYK-LDALNKLYKLNDSQNSELLLNWLRLCIKSKWEECIPKALDFVNSQGRLKFCRPIYRDLAQWPIANKKARDV--YLKGRSQMHPITAEMI 610          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVK--GTETRFDIVDCKIEALGSCLKIPIGI--SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI-KNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE-LQESLN-AYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAK-LHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            DP + AN E     H    W +DF++K I G V++ L ++ +    + LDT+ L ++ V++   G   +        +ALG  L I      S ++  + I+Y ++ N  ALQ+L  E T  +  PYLFSQCQAI+ARS+ PC D+P VKSTY A+V  P     LMSAI +   P++ G   I  F+Q V+I SYL+AIV G+L  K++S R  VW+EP   E + +EFA+TE +L +AE + G YVWG YDL+VLP +FP+GGMENPCLTF+TPTLL GD+SLV V+AHEI+HSWTGNLVTN +WE FWLNEG T ++ER I  K Y  EL R      G  E L  ++N  +G  H++ +LV  L   DPDD+FS VPYEKGS LLF +E   G +    ++L+ Y + Y YK+++T+EWK + Y    DK+ I    LDN+DW  W + +  +P           A + LA KW     E           + E F        L VL+  +  K +    +  +   Y+   + N+E+ F W+ML + +  +P +D    F  + GR+KY KPIYR+L  W     +   +  F  N   MHPIT K+I+
Sbjct:    8 DPSTAANYEQVTVSHYALKWKVDFEKKHIAGDVSITL-DVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQTTDRVAPYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETEKILKVAEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFITPTLLAGDRSLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMY-GELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVI----LDNIDWNLWLH-KAGLPPKPKYDSTPMQACKDLAAKWTTEGSEAP--------TDGEVFAKMSNSQKLAVLDAVRVNKTMFGDRMPALTATYKLDQAKNAELKFSWLMLGLETKWSPIVDASLAFALAVGRMKYCKPIYRSLFGW--SATRDRAISQFKANIPNMHPITVKAIQ 605          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVK--GTETRFDIVDCKIEALGSCLKIPIGI--SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI-KNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE-LQESLN-AYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAK-LHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            DP + AN E     H    W +DF++K I G V++ L ++ +    + LDT+ L ++ V++   G   +        +ALG  L I      S ++  + I+Y ++ N  ALQ+L  E T  +  PYLFSQCQAI+ARS+ PC D+P VKSTY A+V  P     LMSAI +   P++ G   I  F+Q V+I SYL+AIV G+L  K++S R  VW+EP   E + +EFA+TE +L +AE + G YVWG YDL+VLP +FP+GGMENPCLTF+TPTLL GD+SLV V+AHEI+HSWTGNLVTN +WE FWLNEG T ++ER I  K Y  EL R      G  E L  ++N  +G  H++ +LV  L   DPDD+FS VPYEKGS LLF +E   G +    ++L+ Y + Y YK+++T+EWK + Y    DK+ I    LDN+DW  W + +  +P           A + LA KW     E           + E F        L VL+  +  K +    +  +   Y+   + N+E+ F W+ML + +  +P +D    F  + GR+KY KPIYR+L  W     +   +  F  N   MHPIT K+I+
Sbjct:    8 DPSTAANYEQVTVSHYALKWKVDFEKKHIAGDVSITL-DVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQTTDRVAPYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETEKILKVAEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFITPTLLAGDRSLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMY-GELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVI----LDNIDWNLWLH-KAGLPPKPKYDSTPMQACKDLAAKWTTEGSEAP--------TDGEVFAKMSNSQKLAVLDAVRVNKTMFGDRMPALTATYKLDQAKNAELKFSWLMLGLETKWSPIVDASLAFALAVGRMKYCKPIYRSLFGW--SATRDRAISQFKANIPNMHPITVKAIQ 605          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVK--GTETRFDIVDCKIEALGSCLKIPIGI--SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI-KNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE-LQESLN-AYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAK-LHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            DP + AN E     H    W +DF++K I G V++ L ++ +    + LDT+ L ++ V++   G   +        +ALG  L I      S ++  + I+Y ++ N  ALQ+L  E T  +  PYLFSQCQAI+ARS+ PC D+P VKSTY A+V  P     LMSAI +   P++ G   I  F+Q V+I SYL+AIV G+L  K++S R  VW+EP   E + +EFA+TE +L +AE + G YVWG YDL+VLP +FP+GGMENPCLTF+TPTLL GD+SLV V+AHEI+HSWTGNLVTN +WE FWLNEG T ++ER I  K Y  EL R      G  E L  ++N  +G  H++ +LV  L   DPDD+FS VPYEKGS LLF +E   G +    ++L+ Y + Y YK+++T+EWK + Y    DK+ I    LDN+DW  W + +  +P           A + LA KW     E           + E F        L VL+  +  K +    +  +   Y+   + N+E+ F W+ML + +  +P +D    F  + GR+KY KPIYR+L  W     +   +  F  N   MHPIT K+I+
Sbjct:    8 DPSTAANYEQVTVSHYALKWKVDFEKKHIAGDVSITL-DVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQTTDRA-PYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETEKILKVAEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFITPTLLAGDRSLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMY-GELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVI----LDNIDWNLWLH-KAGLPPKPKYDSTPMQACKDLAAKWTTEGSEAP--------TDGEVFAKMSNSQKLAVLDAVRVNKTMFGDRMPALTATYKLDQAKNAELKFSWLMLGLETKWSPIVDASLAFALAVGRMKYCKPIYRSLFGW--SATRDRAISQFKANIPNMHPITVKAIQ 604          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVK--GTETRFDIVDCKIEALGSCLKIPIGI--SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI-KNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE-LQESLN-AYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAK-LHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            DP + AN E     H    W +DF++K I G V++ L ++ +    + LDT+ L ++ V++   G   +        +ALG  L I      S ++  + I+Y ++ N  ALQ+L  E T  +  PYLFSQCQAI+ARS+ PC D+P VKSTY A+V  P     LMSAI +   P++ G   I  F+Q V+I SYL+AIV G+L  K++S R  VW+EP   E + +EFA+TE +L +AE + G YVWG YDL+VLP +FP+GGMENPCLTF+TPTLL GD+SLV V+AHEI+HSWTGNLVTN +WE FWLNEG T ++ER I  K Y  EL R      G  E L  ++N  +G  H++ +LV  L   DPDD+FS VPYEKGS LLF +E   G +    ++L+ Y + Y YK+++T+EWK + Y    DK+ I    LDN+DW  W + +  +P           A + LA KW     E           + E F        L VL+  +  K +    +  +   Y+   + N+E+ F W+ML + +  +P +D    F  + GR+KY KPIYR+L  W     +   +  F  N   MHPIT K+I+
Sbjct:    8 DPSTAANYEQVTVSHYALKWKVDFEKKHIAGDVSITL-DVKQDTERIVLDTRDLSVQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQFLTAEQTTDRA-PYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMSAIGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETEKILKVAEDVAGPYVWGRYDLVVLPATFPFGGMENPCLTFITPTLLAGDRSLVNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMY-GELERQFESESGYEEALVRTVNDVFGPDHEYTKLVQNLGNADPDDAFSSVPYEKGSALLFTIEQALGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVI----LDNIDWNLWLH-KAGLPPKPKYDSTPMQACKDLAAKWTTEGSEAP--------TDGEVFAKMSNSQKLAVLDAVRVNKTMFGDRMPALTATYKLDQAKNAELKFSWLMLGLETKWSPIVDASLAFALAVGRMKYCKPIYRSLFGW--SATRDRAISQFKANIPNMHPITVKAIQ 604          

Query:  104 LSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDI---VDCKIEALGS--CLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNA-YGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLN-PEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKE-AKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            L + DP SY+  +   TEH   +W IDF    I+GSV  + K LT     + LD + +++   ++    +   I   +   ++ +G    L++P G +    +V I Y T+++ + LQWL P  T+GK+HPY+FSQCQAIHARS+ PCQD+P VK TY A V+ P++   LMSA+   D  + G  L   F+Q+V I +YLVAI  G L  + L   S+VW+E  +V+  A EF++T  +L  A  +CG YVW  YDLLV+PPSFP+GGMENPCLTFVTPTLL GDKSL  VVAHEI HSWTGNLVTNK +E FWLNEG T ++E  I+ +   ++ +   ++S  + +LQE +     +  +  +LV  L  C PDD+FS VPY KGS  L +LE++ G   +   +L+ Y + Y YKS+ T ++++  Y Y ID +   K KL  VDW  W       PV         + ++ LA  W + +  E++DS +    +       HQ   FL  L + K+   L+   I  + + Y   +S N+E+ F    L IR+     +D+I +F NS  R+K+ +PIYR+LA WP    K   ++NF+  ++ M  + + +I
Sbjct:    4 LGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALI--DKKEPGKTL---FKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLS-NLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDK--KDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISI-----HQLIDFLGKLIESKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWP--EAKPAAIRNFVNVKDQMMAVCSHTI 606          

Query:  104 LSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDI---VDCKIEALGS--CLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNA-YGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLN-PEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKE-AKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            L + DP SY+  +   TEH   +W IDF    I+GSV  + K LT     + LD + +++   ++    +   I   +   ++ +G    L++P G +    +V I Y T+++ + LQWL P  T+GK+HPY+FSQCQAIHARS+ PCQD+P VK TY A V+ P++   LMSA+   D  + G  L   F+Q+V I +YLVAI  G L  + L   S+VW+E  +V+  A EF++T  +L  A  +CG YVW  YDLLV+PPSFP+GGMENPCLTFVTPTLL GDKSL  VVAHEI HSWTGNLVTNK +E FWLNEG T ++E  I+ +   ++ +   ++S  + +LQE +     +  +  +LV  L  C PDD+FS VPY KGS  L +LE++ G   +   +L+ Y + Y YKS+ T ++++  Y Y ID +   K KL  VDW  W       PV         + ++ LA  W + +  E++DS +    +       HQ   FL  L + K+   L+   I  + + Y   +S N+E+ F    L IR+     +D+I +F NS  R+K+ +PIYR+LA WP    K   ++NF+  ++ M  + + +I
Sbjct:    4 LGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALI--DKKEPGKTL---FKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLS-NLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDK--KDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISI-----HQLIDFLGKLIESKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWP--EAKPAAIRNFVNVKDQMMAVCSHTI 606          

Query:  104 LSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDI---VDCKIEALGS--CLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNA-YGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLN-PEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKE-AKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            L + DP SY+  +   TEH   +W IDF    I+GSV  + K LT     + LD + +++   ++    +   I   +   ++ +G    L++P G +    +V I Y T+++ + LQWL P  T+GK+HPY+FSQCQAIHARS+ PCQD+P VK TY A V+ P++   LMSA+   D  + G  L   F+Q+V I +YLVAI  G L  + L   S+VW+E  +V+  A EF++T  +L  A  +CG YVW  YDLLV+PPSFP+GGMENPCLTFVTPTLL GDKSL  VVAHEI HSWTGNLVTNK +E FWLNEG T ++E  I+ +   ++ +   ++S  + +LQE +     +  +  +LV  L  C PDD+FS VPY KGS  L +LE++ G   +   +L+ Y + Y YKS+ T ++++  Y Y ID +   K KL  VDW  W       PV         + ++ LA  W + +  E++DS +    +       HQ   FL  L + K+   L+   I  + + Y   +S N+E+ F    L IR+     +D+I +F NS  R+K+ +PIYR+LA WP    K   ++NF+  ++ M  + + +I
Sbjct:   75 LGVVDPSSYSQPDLITTEHSALNWKIDFAATKIQGSVLHRFKVLTANLDKILLDVRDINVTNATLLAGGSELPINFFISDAVDDIGQKLTLELPSGTAKGSLNVRIDYETSSSASGLQWLNPTQTLGKEHPYMFSQCQAIHARSVIPCQDTPAVKFTYDATVEHPSELTALMSALI--DKKEPGKTL---FKQEVPIPAYLVAIAIGKLVSRPLGENSSVWAEEAIVDACAEEFSETATMLKTATELCGPYVWKQYDLLVMPPSFPFGGMENPCLTFVTPTLLAGDKSLADVVAHEIAHSWTGNLVTNKNFEHFWLNEGFTVFVESKIVGRMQGAKELDFKMLS-NLTDLQECIRTQLNKTPELTKLVVDLSNCGPDDAFSSVPYIKGSTFLRYLEDLFGGPTVFEPFLRDYLKKYAYKSIETKDFQSALYDYFIDTDK--KDKLSAVDWDLWLKSEGMPPVIPNFDESLANVTKELASLWSSKSVAELADSAEIKTTISI-----HQLIDFLGKLIESKDIVDLNEGKINLLESTYNLKSSKNAEVRFRLNRLIIRARLIKRLDEILEFANSNFRMKFCRPIYRDLAGWP--EAKPAAIRNFVNVKDQMMAVCSHTI 677          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKE--GNHLIHKFEQKVNISSYLVAIVCGNLAGK--KLSNRS--TVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMENPCLT-------FVTPT--LLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLV-------PVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKS 1342
            +Q +   AR  FPC D P  K+++   +    QFN L +    E    E   N++  +F++ V +S+YLVA    + + K   L N +    W+ P  +++  +       +L   E   G  Y     D + +P  F  G MEN  L          +PT   L   + L  V+AHE+ H W GNLVT K W D WLNEG   Y+  L +++ Y     R           + SL A     + + LV       P+ +  + ++SF  + Y+KGS +L  +    G++     L+ Y + Y YK+
Sbjct:  162 TQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVP-DFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRD----------KGSLTALMTAFRLDSLVSSHPISRPIQMVTEIEESFDAISYQKGSAVLRMMHLFMGEESFRTGLREYLKLYAYKN 457          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKE--GNHLIHKFEQKVNISSYLVAIVCGNLAGK--KLSNRS--TVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMENPCLT-------FVTPT--LLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLV-------PVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKS 1342
            +Q +   AR  FPC D P  K+++   +    QFN L +    E    E   N++  +F++ V +S+YLVA    + + K   L N +    W+ P  +++  +       +L   E   G  Y     D + +P  F  G MEN  L          +PT   L   + L  V+AHE+ H W GNLVT K W D WLNEG   Y+  L +++ Y     R           + SL A     + + LV       P+ +  + ++SF  + Y+KGS +L  +    G++     L+ Y + Y YK+
Sbjct:  162 TQFEPSSARKAFPCFDEPGFKASFVVTLGYHKQFNALSNMPVREIRPHESLANYIWCEFQESVPMSTYLVAYSVNDFSFKPSTLPNGALFRTWARPNAIDQCDYAAEFGPKVLQYYEEFFGIRYPLPKIDQMAVP-DFSAGAMENWGLVKYRESTLLYSPTHSSLADKQDLANVIAHELAHQWFGNLVTMKWWTDLWLNEGFATYVAGLGVQEIYPEWHSRD----------KGSLTALMTAFRLDSLVSSHPISRPIQMVTEIEESFDAISYQKGSAVLRMMHLFMGEESFRTGLREYLKLYAYKN 457          

Query:  152 TEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGISDEKFSVC-IQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN---EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLN----PEISDSDQKDL----LLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            T+HL+  + +DFDR +++G V L ++ L  K + L LD+K L I KVS  G   +F++   K +  GS L+I  P  +S  +  +  I+Y T+   TALQWL P+ T GKKHPYLFSQCQA H R++ PCQD+P VK TY A+V  P +   LMSA+++    DP+ + + +I++F Q V + SYL+AIV G L  +++  RS VWSE E V++AA+EFA+TE +L  AES+ G YVWG YD+LVLPPSFPYGGMENPCLTFVTPT+L GD+SL  V+AHEI+HSWTGNLVTN+TWE FWLNEGHT YIER+I  +  + E +R      G  EL ES+  +G  +    LVP L E D D++FS VPYEKG  LL+HLE + G  ++ + ++K Y + + Y S+TT+EWK + + Y  DK +I    L+ VDW  W +     PV         DA   L  KW+          +++D K L    L+E+ + L              +E  L    ++ MG +Y+     N+E+ F W+ +C+++    A+         QGR+K+T+P+++ + N+         VK F +N  ++HP+TA
Sbjct:   18 TKHLNLIYHVDFDRHVLKGKVALTVEVLEDKFSSLTLDSKDLKISKVSANGQAAKFEL-GAKHKFKGSPLEITLPFELSRGQHVIVEIEYETSPTATALQWLTPKQTAGKKHPYLFSQCQATHCRTMVPCQDTPSVKHTYYAQVSVPRELVALMSALRDGQEPDPS-DSSRVIYRFRQPVPMPSYLIAIVVGALESREIGPRSRVWSEKEYVDEAAYEFAETETMLKTAESLAGPYVWGQYDVLVLPPSFPYGGMENPCLTFVTPTVLAGDRSLAGVIAHEISHSWTGNLVTNRTWEHFWLNEGHTVYIERMIA-RCMEGEQLRQFKGIGGWKELHESVKQFGANNVLTNLVPNLHEVDTDEAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYGSVTTEEWKNYLFTYFKDKVDI----LNKVDWNAWMHTPGMAPVRPQYDTTMADACTSLCQKWVKAKEADLASFTEADVKQLNSPQLIEFMALL-------------LQEDPLPLSHVKKMGEVYKLNNIKNAEVRFRWLRICVKAQWEEAVPLALKMATEQGRMKFTRPLFKEVYNF--SKYSDEAVKTFKENRGSLHPVTA 600          

Query:  152 TEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGISDEKFSVC-IQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN---EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLN----PEISDSDQKDL----LLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            T+HL+  + +DFDR +++G V L ++ L  K + L LD+K L I KVS  G   +F++   K +  GS L+I  P  +S  +  +  I+Y T+   TALQWL P+ T GKKHPYLFSQCQA H R++ PCQD+P VK TY A+V  P +   LMSA+++    DP+ + + +I++F Q V + SYL+AIV G L  +++  RS VWSE E V++AA+EFA+TE +L  AES+ G YVWG YD+LVLPPSFPYGGMENPCLTFVTPT+L GD+SL  V+AHEI+HSWTGNLVTN+TWE FWLNEGHT YIER+I  +  + E +R      G  EL ES+  +G  +    LVP L E D D++FS VPYEKG  LL+HLE + G  ++ + ++K Y + + Y S+TT+EWK + + Y  DK +I    L+ VDW  W +     PV         DA   L  KW+          +++D K L    L+E+ + L              +E  L    ++ MG +Y+     N+E+ F W+ +C+++    A+         QGR+K+T+P+++ + N+         VK F +   ++HP+TA
Sbjct:   18 TKHLNLIYHVDFDRHVLKGKVALTVEVLEDKFSSLTLDSKDLKISKVSANGQAAKFEL-GAKHKFKGSPLEITLPFELSRGQHVIVEIEYETSPTATALQWLTPKQTAGKKHPYLFSQCQATHCRTMVPCQDTPSVKHTYYAQVSVPRELVALMSALRDGQEPDPS-DSSRVIYRFRQPVPMPSYLIAIVVGALESREIGPRSRVWSEKEYVDEAAYEFAETETMLKTAESLAGPYVWGQYDVLVLPPSFPYGGMENPCLTFVTPTVLAGDRSLAGVIAHEISHSWTGNLVTNRTWEHFWLNEGHTVYIERMIA-RCMEGEQLRQFKGIGGWKELHESVKQFGANNVLTNLVPNLHEVDTDEAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLFAYGSVTTEEWKNYLFTYFKDKVDI----LNKVDWNAWMHTPGMAPVRPQYDTTMADACTSLCQKWVKAKEADLASFTEADVKQLNSPQLIEFMALL-------------LQEDPLPLSHVKKMGEVYKLNNIKNAEVRFRWLRICVKAQWEEAVPLALKMATEQGRMKFTRPLFKEVYNF--SKYSDEAVKTFKEIRGSLHPVTA 600          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDT-KYLDIKKVSVKGTE---TRFDIVDCKIEALGSCL--KIPIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKIPV-DHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLY-QYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMH 1909
            D  + ++   +  EH   D  +DF +K I G+  ++L+ +   Q++L+LD    L + ++++       TR + +     + G+ L  K P   S D+K  + I+Y  T +   + WL PE T GK  PY+F+Q QA+  RS FPC D+P VKSTYSA V+ P+ F  +MSA K E    +G  L   F  +  I +YLVA+  G+L   ++  R+ VW+EP +++ A  E+ +  E+ LS+ E + G YVWG YD+L +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI HSW GNLVTN TW DFWLNEG T Y +R +  + Y  E    L  + G A L++ ++  GE H  N+L V +    DPDD+++  PYEKG   + +L ++ G + +   +LK Y E +K++S+  ++   F+ +Y  + +  +  K++ +D+  W     W   V D    +     +E LA+KW++ N ++    + DL    +S+  +Q  YFL  +   +++ L    ++ +   Y Q   S+N+E+   W  +  ++ ++P    I DFL+SQG+ KYT P+YR L N  ++  K L ++ F      +H
Sbjct:   16 DVATSSSFRQFKIEHFHLDLKVDFLQKSISGTETIELQCIQDSQSELQLDIHPSLSVHEITLSQNARDWTRTEFLTQDFTSYGTTLLVKFPTAFSSDDKLQLAIRYTAT-DGPGVCWLEPEQTAGKLKPYVFTQGQAVLNRSCFPCFDTPAVKSTYSAAVQVPDGFTAVMSANKWEQRKADGAFL---FTMEHPIPAYLVALAVGDLQSAEVGPRTRVWTEPCLLQAAKQEYDNVIEDFLSVGEKLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIVHEICHSWFGNLVTNATWGDFWLNEGFTMYAQRRVCRELY-GEAYTCLEAATGKALLRQHMDNTGEDHPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLTGDQSRFDTFLKAYVEKFKFRSVLAEDALEFYLEYFPELKERNVHKIEGLDFDSWLNVPGWPPYVPDLSAGQTLMKPAELLAEKWLSHNLDLESICKTDL----KSWKTYQTVYFLDRI--LEKSPLPDGNLKKLEECYSQIIKSNNAELKVRWAQIVAKNQYSPGFQHIRDFLSSQGKQKYTLPVYRALWN-GSEETKALAIEMFSATSGQLH 614          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDT-KYLDIKKVSVKGTE---TRFDIVDCKIEALGSCL--KIPIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKIPV-DHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLY-QYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMH 1909
            D  + ++   +  EH   D  +DF +K I G+  ++L+ +   Q++L+LD    L + ++++       TR + +     + G+ L  K P   S D+K  + I+Y  T +   + WL PE T GK  PY+F+Q QA+  RS FPC D+P VKSTYSA V+ P+ F  +MSA K E    +G  L   F  +  I +YLVA+  G+L   ++  R+ VW+EP +++ A  E+ +  E+ LS+ E + G YVWG YD+L +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI HSW GNLVTN TW DFWLNEG T Y +R +  + Y  E    L  + G A L++ ++  GE H  N+L V +    DPDD+++  PYEKG   + +L ++ G + +   +LK Y E +K++S+  ++   F+ +Y  + +  +  K++ +D+  W     W   V D    +     +E LA+KW++ N ++    + DL    +S+  +Q  YFL  +   +++ L    ++ +   Y Q   S+N+E+   W  +  ++ ++P    I DFL+SQG+ KYT P+YR L N  ++  K L ++ F      +H
Sbjct:   16 DVATSSSFRQFKIEHFHLDLKVDFLQKSISGTETIELQCIQDSQSELQLDIHPSLSVHEITLSQNARDWTRTEFLTQDFTSYGTTLLVKFPTAFSSDDKLQLAIRYTAT-DGPGVCWLEPEQTAGKLKPYVFTQGQAVLNRSCFPCFDTPAVKSTYSAAVQVPDGFTAVMSANKWEQRKADGAFL---FTMEHPIPAYLVALAVGDLQSAEVGPRTRVWTEPCLLQAAKQEYDNVIEDFLSVGEKLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIVHEICHSWFGNLVTNATWGDFWLNEGFTMYAQRRVCRELY-GEAYTCLEAATGKALLRQHMDNTGEDHPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLTGDQSRFDTFLKAYVEKFKFRSVLAEDALEFYLEYFPELKERNVHKIEGLDFDSWLNVPGWPPYVPDLSAGQTLMKPAELLAEKWLSHNLDLESICKTDL----KSWKTYQTVYFLDRI--LEKSPLPDGNLKKLEECYSQIIKSNNAELKVRWAQIVAKNQYSPGFQHIRDFLSSQGKQKYTLPVYRALWN-GSEETKALAIEMFSATSGQLH 614          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTK------YLDIKKVSVKGTETRFDIVDCKIEAL---GSCLKIPIGIS----DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVL-VECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPV---DHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSS-NSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            L D  S +N   +   H   D  ++F  K I G   L+L  +      L LDT        +D K     G    F  +  ++E     GS L I +  +       F V ++Y TT +  A+ WL  E T G+  P +F+Q  ++  RS FPC D+P VKSTYSA V+ P    VLMSA ++    ++    + +F  +  + +YLVA+V G+L    +  RS VW+EP ++  A  +   + E  L++AE + G YVWG YDL+ LPPSFP   MENPCLTF+  ++L   + L+  V HEI H W GN VTN TWE+ WL+EG   Y +R I  + Y  E    L     +  L   +   G+ +  ++L        +P    +   YEKG   + +L  +CG  +    +L+ Y E +++ S+   +   FF  +  + +    A+ + +++++W  G    P+   D    R      + L D W N  P+       DL     S+   Q   FL  L D   + L  +V+  + + Y       N+E+   W+ + +R++  P + ++  FL+      YT P+Y +L       +K   V+ F + +  +HP   ++++
Sbjct:   34 LVDIASASNFHCFKLRHFHLDLHLNFAVKRITGWQVLELTPVQPGVQSLILDTHPSLLIHSVDCKVPGASGAPDVFLSLTYRVEPFTDYGSSLNITLPAAVIRPHRAFRVTVRYTTT-DGPAIWWLDAELTCGQTRPLVFTQGHSVCNRSFFPCFDTPAVKSTYSATVRVPEGVTVLMSASRSAYSKQDR---VFQFSMEYPVPAYLVALVAGDLQHADIGPRSRVWAEPCILTCAVSKLGGSVERWLNVAEGLFGPYVWGRYDLVFLPPSFPIVAMENPCLTFIISSILESQEFLLIDVIHEIAHGWFGNAVTNATWEEMWLSEGLATYAQRRITTEAY-GEAFTCLETVFRLDALHRQMRLLGDNNPVSKLQAKFEPGVNPSSLMNLFTYEKGFCFVSYLSQLCGDIKRFDSFLRAYIEKFRFSSVIAQDLLDFFLGFFPELKEGCVAQREGLEFERWLNG-CGPPLCEPDLSAGRTLTGPVQHLCDLWGNDAPDTQVISTFDL----SSWSTFQTVLFLDRLLD--RSPLSQEVMSLLSSCYAALLDDMNAEVQIRWLQIVVRNSFYPDLPRVRSFLHKHTSRMYTVPLYEDLC---GGVMKCFAVEVFYQTQARLHPNLRRTLQ 646          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGN--HLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPIT 1918
            + DP S+A+ E +  +H++    +DF   +I  S +L +++L    A L LDTK L IKKV+V G + +F +        G+ L+I +  S    ++  V I   T+   +ALQWL  E T GK HPYLFSQCQA H RS+ PCQD+P VK TY ++V  P +   LMSA+++ +  ++ +    I+ F Q V I SYL+A+V G L G+K   R+T+W+E E++E + +EF++TE +L  AE + G YVWG YDLL+LPPSFPYGGMENPCLTFVTPT+L GD+SL  V+AHEI+HSWTGNLVTN+TWE+FWLNEGHT Y+ER I +     E  R      G  ELQ S+N +G  +    LVP L E D D +FS VPYEKG  LLF+LE + G  ++ L +LK Y + + YKS+TT++WK F Y Y  DK +I    LD VDWK W +     PV         +A   L+ KW+        S   D + +  S   HQ    L +L    EA L    ++ M  +Y      NSEI F W+ LCIR+     I         QGR+K+T+P+YR+L N+  +  +  TV  FLKN + MHP+T
Sbjct:    1 MADPSSFASPEKFNIKHMNLKLHVDFASCVITASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDAKFAL-GTSHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLTAEQTAGKVHPYLFSQCQATHCRSIIPCQDTPSVKFTYCSQVSVPKELVALMSALRDGELVEQNDCSRKIYCFMQNVPIPSYLIALVVGALEGRKGGPRTTIWTEKELLEPSVYEFSETEKMLKYAEDLVGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLAGVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRI-DGLLHGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEIDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAYKSVTTEQWKNFLYSYFKDKVDI----LDKVDWKGWMHTPGMPPVQPKYDMTLANACIALSQKWVKAKESDLSSFNADDVKDLSS---HQLIEVLTIL--LLEAPLTVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAKCEDVIPLALKMATEQGRMKFTRPLYRDLYNF--EKAREETVNTFLKNRSCMHPVT 596          

Query:  101 ALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPIT 1918
            A  + DP S+A+ E +  +H++    +DF   +I  S +L +++L    A L LDTK L IKKV+V G + +F +        G+ L+I +  S    ++  V I   T+   +ALQWL  E T GK HPYLFSQCQA H RS+ PCQD+P VK TY ++V  P +   LMSA+++ +                     LV  + G         R+T+W+E E++E + +EF++TE +L  AE + G YVWG YDLL+LPPSFPYGGMENPCLTFVTPT+LV    L+ V+AHEI+HSWTGNLVTN+TWE+FWLNEGHT Y+ER I +     E  R      G  ELQ S+N +G  +    LVP L E D D +FS VPYEKG  LLF+LE + G  ++ L +LK Y + + YKS+TT++WK F Y Y  DK +I    LD VDWK W +     PV         +A   L+ KW+        S   D + +  S   HQ    L +L    EA L    ++ M  +Y      NSEI F W+ LCIR+     I         QGR+K+T+P+YR+L N+  +  +  TV  FLKN + MHP+T
Sbjct:    1 AADMADPSSFASPEKFNIKHMNLKLHVDFASCVITASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDAKFAL-GTSHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLTAEQTAGKVHPYLFSQCQATHCRSIIPCQDTPSVKFTYCSQVSVPKELVALMSALRDGE---------------------LVDCIHGG-------PRTTIWTEKELLEPSVYEFSETEKMLKYAEDLVGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLVWSFFLLIVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRI-DGLLHGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEIDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAYKSVTTEQWKNFLYSYFKDKVDI----LDKVDWKGWMHTPGMPPVQPKYDMTLANACIALSQKWVKAKESDLSSFNADDVKDLSS---HQLIEVLTIL--LLEAPLTVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAKCEDVIPLALKMATEQGRMKFTRPLYRDLYNF--EKAREETVNTFLKNRSCMHPVT 569          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPIT 1918
            L DP S+A+ E +  +H++    +DF   +I  S +L +++L    A L LDTK L IKKV+V G + +F +        G+ L+I +  S    ++  V I   T+   +ALQWL  E T GK HPYLFSQCQA H RS+ PCQD+P VK TY ++V  P +   LMSA+++ +                     LV  + G         R+T+W+E E++E + +EF++TE +L  AE + G YVWG YDLL+LPPSFPYGGMENPCLTFVTPT+LV    L+ V+AHEI+HSWTGNLVTN+TWE+FWLNEGHT Y+ER I +     E  R      G  ELQ S+N +G  +    LVP L E D D +FS VPYEKG  LLF+LE + G  ++ L +LK Y + + YKS+TT++WK F Y Y  DK +I    LD VDWK W +     PV   +K  HG  S+       + N +    D KDL         HQ    L +L    EA L    ++ M  +Y      NSEI F W+ LCIR+     I         QGR+K+T+P+YR+L N+  +  +  TV  FLKN + MHP+T
Sbjct:    5 LRDPSSFASPEKFNIKHMNLKLHVDFASCVITASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDAKFAL-GTSHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLTAEQTAGKVHPYLFSQCQATHCRSIIPCQDTPSVKFTYCSQVSVPKELVALMSALRDGE---------------------LVDCIHGG-------PRTTIWTEKELLEPSVYEFSETEKMLKYAEDLVGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLVWSFFLLIVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRI-DGLLHGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEIDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAYKSVTTEQWKNFLYSYFKDKVDI----LDKVDWKGWMHTPGMPPVQPNVKILHGIFSQAKESDLSSFNAD----DVKDL-------SSHQLIEVLTIL--LLEAPLTVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAKCEDVIPLALKMATEQGRMKFTRPLYRDLYNF--EKAREETVNTFLKNRSCMHPVT 562          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPIT 1918
            + DP S+A+ E +  +H++    +DF   +I  S +L +++L    A L LDTK L IKKV+V G + +F +        G+ L+I +  S    ++  V I   T+   +ALQWL  E T GK HPYLFSQCQA H RS+ PCQD+P VK TY ++V  P +   LMSA+++ +                        +V  N   +K+      W   +M+ K    F  TE +L  AE + G YVWG YDLL+LPPSFPYGGMENPCLTFVTPT+LV    L+ V+AHEI+HSWTGNLVTN+TWE+FWLNEGHT Y+ER I +     E  R      G  ELQ S+N +G  +    LVP L E D D +FS VPYEKG  LLF+LE + G  ++ L +LK Y + + YKS+TT++WK F Y Y  DK +I    LD VDWK W +     PV   +K  HG  S+       + N +    D KDL         HQ    L +L    EA L    ++ M  +Y      NSEI F W+ LCIR+     I         QGR+K+T+P+YR+L N+  +  +  TV  FLKN + MHP+T
Sbjct:    1 MADPSSFASPEKFNIKHMNLKLHVDFASCVITASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDAKFAL-GTSHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLTAEQTAGKVHPYLFSQCQATHCRSIIPCQDTPSVKFTYCSQVSVPKELVALMSALRDGE------------------------LVEQNDCSRKIYCFMQNW---QMLGKGFFSF--TEKMLKYAEDLVGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLVWSFFLLIVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRI-DGLLHGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEIDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAYKSVTTEQWKNFLYSYFKDKVDI----LDKVDWKGWMHTPGMPPVQPNVKILHGIFSQAKESDLSSFNAD----DVKDL-------SSHQLIEVLTIL--LLEAPLTVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAKCEDVIPLALKMATEQGRMKFTRPLYRDLYNF--EKAREETVNTFLKNRSCMHPVT 557          

Query:  260 LDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPIT 1918
            LDTK L IKKV+V G + +F +        G+ L+I +  S    ++  V I   T+   +ALQWL  E T GK HPYLFSQCQA H RS+ PCQD+P VK TY ++V  P +   LMSA+++ +   E N    K             I C    G     R+T+W+E E++E + +EF++TE +L  AE + G YVWG YDLL+LPPSFPYGGMENPCLTFVTPT+LV    L+ V+AHEI+HSWTGNLVTN+TWE+FWLNEGHT Y+ER I +     E  R      G  ELQ S+N +G  +    LVP L E D D +FS VPYEKG  LLF+LE + G  ++ L +LK Y + + YKS+TT++WK F Y Y  DK +I    LD VDWK W +     PV   +K  HG  S+       + N +    D KDL         HQ    L +L    EA L    ++ M  +Y      NSEI F W+ LCIR+     I         QGR+K+T+P+YR+L N+  +  +  TV  FLKN + MHP+T
Sbjct:   30 LDTKDLTIKKVAVNGKDAKFAL-GTSHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLTAEQTAGKVHPYLFSQCQATHCRSIIPCQDTPSVKFTYCSQVSVPKELVALMSALRDGELV-EQNDCSRK-------------IYCFMQNG---GPRTTIWTEKELLEPSVYEFSETEKMLKYAEDLVGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLVWSFFLLIVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRI-DGLLHGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEIDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAYKSVTTEQWKNFLYSYFKDKVDI----LDKVDWKGWMHTPGMPPVQPNVKILHGIFSQAKESDLSSFNAD----DVKDL-------SSHQLIEVLTIL--LLEAPLTVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAKCEDVIPLALKMATEQGRMKFTRPLYRDLYNF--EKAREETVNTFLKNRSCMHPVT 548          

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFL-QVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     +DF R+ + G+  L +++  +    L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I++F Q+V I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ ++  +GE H F +LV  L + DPD ++S +PYEKG  LLF+LE + G  ++ L +LK Y + + Y+S+TTD+WK+F Y +  DK ++    L+ VDW  W Y     PV         +A   L+ +W+    E     S +D KDL         HQ   FL QVL   ++A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V  + +++ +MHP+TA
Sbjct:    9 SLASPASVCR-----TQHLHLRCSVDFARRTLTGTAALTVQSQEENLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYK-GSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRK----IYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDDWKSFLYSHFKDKVDL----LNQVDWNTWLYAPGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLSSFSIADLKDL-------SSHQLNEFLAQVL---QKAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVHTYQEHKASMHPVTA 601          

Query:  341 EALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKI------PVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLY-QYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMH 1909
            +AL    + P G +D +F + + Y        + WL PE T GKK P++++Q QA+  R+ FPC D+P VK TYSA ++ P+ F  +MSA   E   K G +    F+    I SYL+A+  G+LA  ++  RS VW+EP ++E A  E++   E  L+  E + G YVWG YDLL +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI+HSW GNLVTN  W +FWLNEG T Y +R I    + +     L  + G A L++ +N  GE +  N+L V +    DPDD+++  PYEKG   + +L ++ G +DQ  ++LK Y + +K++S+  +++  F+ +Y  + +      +   ++ +W     W        P D ++K      +E LA+ W+   P++    Q    +   ++  +Q  YFL  +   +++ L    ++ +G  Y + + + N+E+   W  + +++++     ++ DFL SQG+ KYT P+Y  +    ++  + L    F    + +H
Sbjct:  120 QALCVAFRQPCGAAD-RFELELTY-RVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWE---KRGPNKFF-FQMSHPIPSYLIALAIGDLASAEVGPRSRVWAEPCLIEAAKEEYSGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT-CLEAATGRALLRQHMNVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDSLMK-----PAEELAELWVTSEPDM----QAIEAVAISTWKTYQLVYFLDKI--LQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTLPLYHAMMGG-SEMARTLAKDTFAATASQLH 634          

Query:  341 EALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICG-KDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKI------PVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLY-QYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMH 1909
            +AL    + P G +D +F + + Y        + WL PE T GKK P++++Q QA+  R+ FPC D+P VK TYSA ++ P+ F  +MSA   E   K G +    F+    I SYL+A+  G+LA  ++  R                                      YDLL +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI+HSW GNLVTN  W +FWLNEG T Y +R I    + +     L  + G A L++ +N  GE +  N+L V +    DPDD+++  PYEKG   + +L ++ G +DQ  ++LK Y + +K++S+  +++  F+ +Y  + +      +   ++ +W     W        P D ++K      +E LA+ W+   P++    Q    +   ++  +Q  YFL  +   +++ L    ++ +G  Y + + + N+E+   W  + +++++     ++ DFL SQG+ KYT P+Y  +    ++  + L    F    + +H
Sbjct:  120 QALCVAFRQPCGAAD-RFELELTY-RVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKCTYSALIEVPDGFTAVMSADTWE---KRGPNKFF-FQMSHPIPSYLIALAIGDLASAEVGPR--------------------------------------YDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT-CLEAATGRALLRQHMNVSGEENPLNKLRVKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQDQFDKFLKAYVDEFKFQSILAEDFLEFYLEYFPELKKKGVDSIPGFEFDRWLNTPGWPPYLPDLSPGDSLMK-----PAEELAELWVTSEPDM----QAIEAVAISTWKTYQLVYFLDKI--LQKSPLPPGNVKKLGETYPKISNAQNAELRLRWGQIILKNDYQEEFQKVKDFLQSQGKQKYTLPLYHAMMGG-SEMARTLAKDTFAATASQLH 595          

Query:  386 EKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINL--NPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSS-NSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSIR 1933
            + F V ++Y +T +  A+ WL PE T G   P++F+Q  ++  RS FPC D+P VK TYSA VKAP    VLMSA ++    +EG   ++ F  +  + +YLVA+V G+L    +  RS VW+EP ++  A  + +   E  LS AE + G Y+WG YD++ LPPSFP   MENPCLTF+  ++L  D+ LV  V HE+ HSW GN VTN TWE+ WL+EG   Y +R I  + Y +     L  +  +  L   +   GE    ++L V +    +P    +   YEKG   +++L  +CG  Q    +L+ Y E YK+ S+   +    F  +  + +  S      +++++W         +  L +  G +  R  +    L     +  +      ++   +   Q   FL  L D   + L  +V+ ++   Y     S N+EI   W+ + +R+++ P + ++  FL SQ    YT P+Y +L       +K   ++ F + +  +HP   ++I+
Sbjct:  156 QPFQVILRYTST-DAPAIWWLDPELTYGNAKPFVFTQGHSVCNRSFFPCFDTPAVKCTYSAVVKAPLGVQVLMSATQSVYVEEEG---LYHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGPYMWGRYDIVFLPPSFPIVAMENPCLTFIISSILESDEFLVIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFT-CLETAFRLDALHRQMRLLGEDSPVSKLQVKLEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGGPQRFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEFERWLNATGPPLAEPDLSQ--GSSLTRPVEALFQLWTAEPLEQAAASASAIDISKWRTFQTALFLDRLLD--GSPLPQEVVMSLSKCYSSLLDSMNAEIRIRWLQIVVRNDYYPDLHRVRRFLESQMSRMYTIPLYEDLC---TGALKSFALEVFYQTQGRLHPNLRRTIQ 665          

Query:  206 GSVNLQLKNLTKKQADLKLDTKYLDIKKVS----VKGTETRFDIVDCKI-EALGSCLKIPIGISDEKFSVCIQYATTANCT--ALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI--KNEDPTKEGNHLIH-KFEQKVNISSYLVAIVCG---NLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLL-------VGDKSLVF-VVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRH--LLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAF 1369
            GSV + L+ L   + D+ L +   +I +V+    V   E + +I++    E +      P+ ++   +++ I+Y+   + +      +       +K  +  +Q + + ARS FPC D P  K+T+  K+   N+ +  +S +  K+  P +EG  LI  +F + V +S+YLVA + G   NL+        +V++ PE + +  H    T  LL   ++    +Y     DL+ +P  F  G MEN   LTF   TLL       V D+ LV  ++AHE+ H W GNLVT + W D WLNEG   ++E   +EK +  EL  +   L +      ++SLN+    H  +  V    +   ++ F  + Y KG++LL  L++   +D     +  Y  ++ Y ++ +D+ W +F
Sbjct:  192 GSVTISLQALQDTR-DIILHSTGHNISRVTFMSAVSSQEKQVEILEYPYHEQIAVVAPEPL-LTGHNYTLKIEYSANISNSYYGFYGITYTDKSNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKI-TRNEHHTALSNMPKKSSVPAEEG--LIQDEFSESVKMSTYLVAFIVGEMRNLSQDVNGTLVSVYAVPEKIGQVHHALDTTIKLLEFYQTYFEIQYPLKKLDLVAIP-DFEAGAMENWGLLTFREETLLYDNATSSVADRKLVTKIIAHELAHQWFGNLVTMQWWNDLWLNEGFATFMEYFSVEKIF-KELNSYEDFLDARFKTMRKDSLNS---SHPISSSVQSSEQI--EEMFDSLSYFKGASLLLMLKSYLSEDVFRHAVILYLHNHSYAAIQSDDLWDSF 593          

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGIS---DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN-EDPTKEG-NHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWI-----NLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     IDF R+++ G+  L +++       L LDTK L I+KV + G E ++ + + +    GS ++I + I+   +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TYSA+V  P +   LMSAI++ E P  E  N  I++F QKV I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G Y+WG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ S+  +GE H F +LV  L   DPD ++S VPYEKG  LLF+LE + G  ++ L +LK Y E + YKS+TTD WK F Y +  DK +I    L+ VDW  W Y     PV         +A   L+ +WI     +LN   S +D KD       F  HQ   FL  +   + A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   ++ + +++ +MHP+TA
Sbjct:    9 SLASPASVCQ-----TKHLHLRCSIDFTRRVLSGTAALTIQSQEDNLRSLILDTKDLTIEKVVINGQEVKYTLGE-RQSYKGSPIEISLPIALCKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYSAEVSVPKELVALMSAIRDGEAPDPEDPNRKIYRFSQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYIWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFHALGGWGELQNSIKTFGETHPFTKLVVDLTNTDPDVAYSSVPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYKSITTDNWKDFLYSHFKDKVDI----LNQVDWNTWLYSPGLPPVKPNYDMTLTNACISLSQRWITAKDDDLN-SFSSADLKD-------FSSHQVNEFLAQM--LQNAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AIRTYKEHKASMHPVTA 601          

Query:  152 TEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFL-QVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            T+HL     +DF  + + G   L +++       L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSA+++      EDP+++    I+KF QKV I  YL+A+V G L  +K+  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ ++  +GE H F +LV  L + DPD ++S VPYEKG  LLFHLE + G  ++ L +LK Y E + YKS+TTD+WK F Y +  DK +I    L+ VDW  W Y     PV         +A   L+ +WI    E     + +D KDL         HQ   FL QVL   ++A L    ++ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   ++ +  ++ +MHP+TA
Sbjct:   19 TKHLHLRCSVDFSSRALTGIAALTIQSQEDNLRSLVLDTKALTIEKVVINGQEVKYALGE-RQSYKGSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAVLPCQDTPSVKLTYTAEVSVPKELVALMSAVRDGETPDPEDPSRK----IYKFNQKVPIPCYLIALVVGALESRKIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFHALGGWGELQNTIKTFGETHPFTKLVVDLTDVDPDVAYSSVPYEKGFALLFHLEQLLGGPEVFLGFLKAYVERFSYKSITTDDWKNFLYSHFKDKVDI----LNQVDWNAWLYSPGLPPVKPNYDMTLTNACIALSQRWITAKEEDLNTFNATDLKDLST-------HQVNEFLAQVL---QQAPLPLGHVKRMQEVYNFNAVNNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AIRTYQAHKASMHPVTA 601          

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     +DF R+ + G+  L +++       L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I+KF QKV I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ S+  +GE H F +LV  L + DPD ++S VPYEKG  LLF+LE + G  ++ L +LK Y E + YKS+TTD+WK F Y Y  DK ++    L+ VDW  W Y     P+         +A   L+ +WI    +     + +D KDL         HQ   FL      + A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V+ + +++ +MHP+TA
Sbjct:    9 SLASPASVCR-----TKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGE-RQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRK----IYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDV----LNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAKEDDLNSFNATDLKDL-------SSHQLNEFLA--QTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKASMHPVTA 601          

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFL-QVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     +DF R+ + G+  L +++  +    L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQCQAIH R++ PCQD+P VK TY+A+V  P +   LMSAI++      EDP+++    I++F Q+V I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ ++  +GE H F +LV  L + DPD ++S +PYEKG  LLF+LE + G  ++ L +LK Y + + Y+S+TTD+WK+F Y +  DK ++    L+ VDW  W Y     PV         +A   L+ +W+    E     S +D KDL         HQ   FL QVL   ++A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V  + +++ +MHP+TA
Sbjct:    9 SLASPASVCR-----TQHLHLRCSVDFARRTLTGTAALTVQSQEENLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYK-GSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRK----IYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSANEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVKKFSYQSVTTDDWKSFLYSHFKDKVDL----LNQVDWNTWLYAPGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLSSFSIADLKDL-------SSHQLNEFLAQVL---QKAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVHTYQEHKASMHPVTA 601          

Query:  107 SLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFL-QVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            SL  P S        T+HL     +DF R+ + G+  L +++       L LDTK L I+KV + G E ++ + + +    GS ++I  PI +S +++  + I + T+   +ALQWL PE T GK+HPYLFSQ +AIH R++ PCQD+  VK TY+A+V  P +   LMSAI++      EDP+++    I++F Q+V I  YL+A+V G L  +++  R+ VWSE E VEK+A+EF++TE++L IAE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GDKSL  V+AHEI+HSWTGNLVTNKTW+ FWLNEGHT Y+ER I  + +  E  RH     G  ELQ ++  +GE H F +LV  L + DPD ++S +PYEKG  LLF+LE + G  ++ L +LK Y E + Y+S+TTD+WK+F Y +  DK ++    L+ VDW  W Y     PV         +A   L+ +W+    E     S  D KDL         HQ   FL QVL   + A L    I+ M  +Y +   +NSEI F W+ LCI+S    AI         QGR+K+T+P++++LA +   H +   V+ + +++  MHP+TA
Sbjct:    9 SLASPASVCR-----TQHLHLRCSVDFARRALTGTAALTVQSQEDNLRTLTLDTKDLTIEKVVINGQEVKYTLGESQGYK-GSPMEISLPIALSKNQEVVIEISFETSPKSSALQWLTPEQTSGKQHPYLFSQWEAIHCRAILPCQDT-SVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDPSRK----IYRFNQRVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLF-GEKFRHFHALGGWGELQNTIKTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLLGGPEVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKDKVDL----LNQVDWNAWLYAPGLPPVKPNYDVTLTNACIALSQRWVTAKEEDLNSFSIEDLKDL-------SSHQLNEFLAQVL---QRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRLCIQSKWEEAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKACMHPVTA 600          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNL---TKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTK--EGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLE-YESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            DP S +N E ++T H++FDW IDF+ K I G V  ++      T     L  D K L+I KV +  TET++ + D     LGSCLKI +      F++ I Y T+    ALQWL    T  K+ P+LF+QCQAIHARSLFPCQD+P VK TY+A V+A     VLMSA    D T+     + +H FEQ + + SYLVA+VCG+L   ++  RS VW+EP +VE+AA EF + + ++S AE ICG Y WG YD+LVLPPSFP+GGMENPCLTFVTPTLL GD+SL+  +AHE +HSWTGNLVTN +WE+FWLNEGHT+Y+E L++E  Y  +  R L I +G  ELQ  L  + +GH F +LVP L   DPDD FS +PY+KGS LL+ LE   GK  ML+WL+ Y +H++  SL+T  W  F  K       +    L  V+W  WFY    IP      R      + +    I     I+D +    +   YES +P Q+   LQ L   +   +H   +  +  + Q + S NSE+ + W ++C+RS + P +    +FLNSQGR+K+T+PIY+ L +     I    + NF      MHP TAK +
Sbjct:   19 DPSSNSNPEYFLTRHVNFDWTIDFNTKTISGCVAYEMVAFDLSTAPDQMLVFDVKDLEISKVCINETETKWLVTDGPHPQLGSCLKIHLPEQTASFTLHIGYQTSPQSPALQWLDAAITADKQKPFLFTQCQAIHARSLFPCQDTPRVKFTYTATVRADPCMTVLMSAKYCADSTECPSSGNPVHNFEQPIPVPSYLVALVCGDLRSAQIGPRSKVWAEPSVVERAAFEFGEVDQVISAAERICGPYQWGNYDILVLPPSFPFGGMENPCLTFVTPTLLAGDRSLICTIAHEASHSWTGNLVTNASWENFWLNEGHTKYLEGLVLEAMYGVD-YRELHIELGYEELQACLADFKQGHPFTKLVPCLDGVDPDDCFSIIPYQKGSLLLYFLEQKYGKPAMLKWLRAYLDHFRGLSLSTRSWLDFLSK------QLGPNVLTEVNWNDWFYKTGAIPWVPKFTRKLSTVCDSVVSA-ITKEVLINDPNVASFVRSTYESLMPLQRQLVLQRL--LERVPIHHDNLRVLDQMLQISQSKNSELRYRWSLICLRSQYLPGLHSALEFLNSQGRMKFTRPIYKALMS--CQSIAEQAINNFKAQRQNMHPTTAKLV 617          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNL---TKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLL-EYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            ++DP S +N E ++T+H+DFDW +DFD K++ G V L L  +      +  L+LD K +++ ++ +      F +       LG+ L I +G+   +F V I+Y T    +ALQWL  + T  KK P+LF+QCQAIHARSLFPCQD+P VK T+SA V AP +  VLM A ++      ++P K     IH F Q + I SYLVA+ CG L   ++  RS VW+EP ++  A  EF   ++++++AES+CG+Y WG+YD+LVLPPSFPYGGMENPCLTFVTP LL GDKSL  V+AHEI HSWTGNLVTN +WE FWLNEGHT+Y+E LI+E+ Y ++  R L I +G  EL   L  + EGH   ++VP L     DD+FS VPY+KGS  L+ LEN  GK  +L WLK Y  H++  SL+T  W  F   ++       K  L  +DW  W Y    IP      R      +++A++ I   P  SD++    +  +YE+ LP Q+    + L   K   L    +  + N+   +TS N+EI F W ++ + S + P +D   +FLNSQGR+KYT+PIY+ L  WP+  IK+  + N+  N+  MHP TAK +
Sbjct:   17 IDDPSSESNPELFLTQHVDFDWKVDFDAKVVSGCVKLHLMPMDFFASCRDTLRLDIKDINVSRIHINNEPVEFTVDAGSYPNLGNVLSIKVGLQTSRFVVVIEYCTMPQSSALQWLDAQMTADKKQPFLFTQCQAIHARSLFPCQDTPRVKFTFSASVLAPPEVTVLMGAHRSTPSGHCDEPEKPS---IHYFHQDIPIPSYLVALACGELDHARIGQRSFVWAEPSVLPWAKAEFEGVDDMIAVAESLCGDYEWGVYDILVLPPSFPYGGMENPCLTFVTPCLLAGDKSLTSVIAHEIAHSWTGNLVTNASWEHFWLNEGHTKYVEGLILERLYGTDY-RELFIDLGYEELLVCLEEFKEGHPLAKMVPCLKGIHTDDAFSIVPYQKGSLFLYFLENKYGKAAVLSWLKSYISHFRRHSLSTRVWIEFLAAHL------GKNILQEIDWNTWLYHAGSIPWVPKTNRKLSSVVDKVAER-IKNTPLGSDAESAAYVRGQYETMLPLQRQLLWRRL--LKCVPLSHDNLLVLNNMLAVSTSKNAEIRFLWSLIVLYSQYLPGVDGALEFLNSQGRMKYTRPIYKALVAWPS--IKQQAINNYKANKQYMHPTTAKLV 618          

Query:  113 NDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNL---TKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTK--EGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLE-YESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
             DP S +N E ++T H++FDW IDF+ K I G V  ++      T     L  D K L+I KV +  TET++ + D     LGSCLKI +      F++ I Y T+    ALQWL    T  K+ P+LF+QCQAIHARSLFPCQD+P VK TY+A V+A     VLMSA    D T+     + +H FEQ + + SYLVA+VCG+L   ++  RS VW+EP +VE+AA EF + + ++S AE ICG Y WG YD+LVLPPSFP+GGMENPCLTFVTPTLL GD+SL+  +AHE +HSWTGNLVTN +WE+FWLNEGHT+Y+E L++E  Y  +  R L I +G  ELQ  L  + +GH F +LVP L   DPDD FS +PY+KGS LL+ LE   GK  ML+WL+ Y +H++  SL+T  W  F  K       +    L  V+W  WFY    IP      R      + +    I      SD++  D +   YE  +  Q+   LQ L   +        +  +  ++Q + + NSEI + W ++C+RS + P +    +FLNSQGR+K+T+PIY+ L +WP+  +    + NF      MHP TAK +
Sbjct:   18 RDPSSNSNPEYFLTRHVNFDWTIDFNTKTISGCVAYEMVAFDLSTAPDQMLVFDVKDLEISKVCINETETKWLVTDGPHPQLGSCLKIHLPEQTASFTLHIGYQTSPQSPALQWLDAAITADKQKPFLFTQCQAIHARSLFPCQDTPRVKFTYTATVRADPCMTVLMSAKYCADSTECPSSGNPVHNFEQPIPVPSYLVALVCGDLRSAQIGPRSKVWAEPSVVERAAFEFGEVDQVISAAERICGPYQWGNYDILVLPPSFPFGGMENPCLTFVTPTLLAGDRSLICTIAHEASHSWTGNLVTNASWENFWLNEGHTKYLEGLVLEAMYGVDY-RELHIELGYEELQACLADFKQGHPFTKLVPCLDGVDPDDCFSIIPYQKGSLLLYFLEQKYGKPAMLKWLRAYLDHFRGLSLSTRSWLDFLSK------QLGPNVLTEVNWDDWFYKTDAIPWVPNFTRKLSTVCDSVVSA-ITKEDLRSDANVADSVRSTYEGLVSLQRQLVLQRL--LERVPFPHDNLRVLDQMFQISQAKNSEIRYRWSLICLRSQYLPGLHSALEFLNSQGRMKFTRPIYKALMSWPS--VAEQAISNFKAQRQNMHPTTAKLV 617          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNL---TKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN------EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLL-EYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            ++DP S +N E ++T+H+DFDW +DFD K++ G V L L  +      +  L+LD K +++ ++ +      F +       LG+ L I +G+   +F V I+Y T    +ALQWL  + T  KK P+LF+QCQAIHARSLFPCQD+P VK T+SA V AP +  VLM A ++      ++P K     IH F Q + I SYLVA+ CG L   ++  RS VW+EP ++  A  EF   ++++++AES+CG+Y WG+YD+LVLPPSFPYGGMENPCLTFVTP LL GDKSL  V+AHEI HSWTGNLVTN +WE FWLNEGHT+Y+E LI+E+ Y ++  R L I +G  EL   L  + EGH   ++VP L     DD+FS VPY+KGS  L+ LEN  GK  +L WLK Y  H++  SL+T  W  F   ++       K  L  +DW  W Y    IP      R      +++A++ I   P  SD++    +  +YE+ LP Q+    + L   K   L    +  + N+   +TS N+EI F W ++ + S + P +D   +FLNSQGR+KYT+PIY+ L  WP+  IK+  + N+  N+  MHP TAK +
Sbjct:   30 IDDPSSESNPELFLTQHVDFDWKVDFDAKVVSGCVKLHLMPMDFFASCRDTLRLDIKDINVSRIHINNEPVEFTVDAGSYPNLGNVLSIKVGLQTSRFVVVIEYCTMPQSSALQWLDAQMTADKKQPFLFTQCQAIHARSLFPCQDTPRVKFTFSASVLAPPEVTVLMGAHRSTPSGHCDEPEKPS---IHYFHQDIPIPSYLVALACGELDHARIGQRSFVWAEPSVLPWAKAEFEGVDDMIAVAESLCGDYEWGVYDILVLPPSFPYGGMENPCLTFVTPCLLAGDKSLTSVIAHEIAHSWTGNLVTNASWEHFWLNEGHTKYVEGLILERLYGTDY-RELFIDLGYEELLVCLEEFKEGHPLAKMVPCLKGIHTDDAFSIVPYQKGSLFLYFLENKYGKAAVLSWLKSYISHFRRHSLSTRVWIEFLAAHL------GKNILQEIDWNTWLYHAGSIPWVPKTNRKLSSVVDKVAER-IKNTPLGSDAESAAYVRGQYETMLPLQRQLLWRRL--LKCVPLSHDNLLVLNNMLAVSTSKNAEIRFLWSLIVLYSQYLPGVDGALEFLNSQGRMKYTRPIYKALVAWPS--IKQQAINNYKANKQYMHPTTAKLV 631          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQAD---LKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPT---KEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLL-LEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            + DP S +N E +VT+H+DFDW +DF+ +++ G V L +  L    AD   LKLD K +++  V++      F I +     LG+ L + +G     F+V I+Y TT   +ALQWL  + T  KK P+LF+QCQAIHARSLFPCQD+P VK TY+A V AP    VLMSA +   P    +  +  +H F Q + I SYLVA+ CG L   ++ +RS VW+EP ++ +A  EF + + L++ AES+CGEY WGIYD+LVLPPSFPYGGMENPCLTFVTPTLL GD+SL  V+AHEI+HSWTGNLVTN +WE FWLNEGHT+Y+E L++E  Y ++  R L I +G  ELQ  L  + EGH   ++VP L     DD+FS +PY+KGS LL++LE   GK  +L WLK Y  H++  SL+T  W  F   ++       +  L  V+W +W YG   IP      R      +++ ++ I   P  SD+D    +  +YE  +P Q+    Q L   K   L    +  + ++   + S N+EI + W ++ + S + P +D   +FLNSQGR+K+T+PIY+ L  WP   I++  + NF  +   +HP TAK +
Sbjct:   17 VQDPSSQSNPELFVTQHVDFDWKVDFNARVLSGKVTLHMTPLDLYSADSVALKLDIKDINVLCVNINEKPAEFTIQNGSHPNLGNVLCVDVGYQRSGFTVVIEYDTTPQSSALQWLDAQMTADKKCPFLFTQCQAIHARSLFPCQDTPRVKFTYTACVIAPPGVTVLMSAQRPTSPRHCDEPESPSMHFFTQDIPIPSYLVALACGELVSARIGSRSLVWAEPSVLPRAQLEFNEVDTLIAAAESLCGEYEWGIYDILVLPPSFPYGGMENPCLTFVTPTLLAGDRSLTSVIAHEISHSWTGNLVTNASWEHFWLNEGHTKYVEGLVLELLYGTDY-RELFIELGYEELQICLGEFKEGHPLAKMVPCLTGVHTDDAFSVIPYQKGSLLLYYLEQTYGKAAILSWLKSYISHFRRHSLSTRTWMDFLAAHL------GQTVLQEVNWNEWLYGSGPIPWVPKSDRKLSSVVDQVVER-IRSTPLGSDTDSAAYVRCQYELMIPLQRQLLWQRL--LKYIPLSHDNLRVLDSMLAVSRSQNAEIRYRWSLIVLYSQYLPGVDCALEFLNSQGRMKFTRPIYKALMAWPT--IRQQAINNFKSHRPFLHPTTAKLV 618          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN---EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPV---DHVLKRDHGDASERLADKWINL-NPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYR--NLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            + D  S+++    +T HL+     DF  +++ G V L ++ L  K + L LDTK L I KVS  G   +F++   +    GS L I  P  +S +   V ++Y T+ + +ALQWL P  T GKKHPYLFSQCQA H R++ PCQD+P VK TY A+V  P +   +MSA+++    DPT + + +I++F Q V + SYL+A+V G L  +++  RS VWSE E V++ A EF +TE +L  AES+ G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL GD+SL  V+AHEI+HSWTGNLVTNKTWE F                                       ++ +G  +    LV  L   +PD+ FS VPYEKG  LL+HLE + G    + ++K Y + + Y S+TT++WK + + Y  DK +I    L+ VDW  W Y     P    D  L     DA   LA +W    + ++S   + D+    +    HQ   FL +L    +  L +  ++ M  +Y++ + +NSEI   W+ LC++S    A+         QGR+K+T+P++   N A + ++      VK F ++ N MH +TA
Sbjct:    4 VTDHCSFSSFSKCLTRHLNLSLQADFSSRVLRGRVALTVEVLEDKFSSLTLDTKDLKIFKVSANGQAAKFEL-GAQHGFKGSPLDITLPFELSGQHVIVEVEYETSPSASALQWLSPAQTAGKKHPYLFSQCQATHCRTMVPCQDTPSVKHTYYAQVSVPKELIAVMSAVRDGQEADPT-DSSRVIYRFRQPVPMPSYLIALVVGALESREIGPRSRVWSEKEHVDQGAFEFTETETMLKTAESLAGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDRSLSNVIAHEISHSWTGNLVTNKTWEHF---------------------------------------VHQFGANNAATNLVVNLEGVNPDECFSCVPYEKGFALLYHLEELMGGPVFMGFVKSYIQMFAYSSVTTEQWKDYLFTYFKDKVDI----LNKVDWNGWMYTPGMPPFKPYDTTL----ADACNALAQRWTKAKDADLSGFSEADI----KQLSSHQLIEFLALLL--LQDPLPTSHVKRMQEVYKFNSINNSEIR-CWLRLCVKSEWEDAVPLALKMATEQGRMKFTRPLFDVYNFAKFRDE-----AVKVFKEHRNEMHSVTA 557          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGISDEKFSVC-IQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINL-NPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            + D  S+++    +T HL+     DF  +++ G V L ++ L  K + L LDTK L I KVS  G   +F++   +    GS L I  P  +S  +  +  ++Y T+ + +ALQWL P  T GKKHPYLFSQCQA H R++ P                   Q ++ +   +  DPT + + +I++F Q V + SYL+A+V G L  +++  RS VWSE E V++ A EF +TE +L  AES+ G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLLV   +   V+AHEI+HSWTGNLVTNKTWE FWLNEGHT Y+ER+I                         ++ +G  +    LV  L   +PD+ FS VPYEKG  LL+HLE + G  ++ + ++K Y + + Y S+TT++WK + + Y  DK +I    L+ VDW  W Y     P          DA   LA +W    + ++S   + D+    +    HQ   FL +L   +   L +  ++ M  +Y++ + +NSEI   W+ LC++S    A+         QGR+K+T+P++R++ N+     +   VK F ++ N MH +TA
Sbjct:    4 VTDHCSFSSFSKCLTRHLNLSLQADFSSRVLRGRVALTVEVLEDKFSSLTLDTKDLKIFKVSANGQAAKFEL-GAQHGFKGSPLDITLPFELSRGQHVIVEVEYETSPSASALQWLSPAQTAGKKHPYLFSQCQATHCRTMVP---------------NLLTQTHIAVRDGQEADPT-DSSRVIYRFRQPVPMPSYLIALVVGALESREIGPRSRVWSEKEHVDQGAFEFTETETMLKTAESLAGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLVSTCNSPGVIAHEISHSWTGNLVTNKTWEHFWLNEGHTVYLERMIGR-----------------------VHQFGANNAATNLVVNLEGVNPDECFSCVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQMFAYSSVTTEQWKDYLFTYFKDKVDI----LNKVDWNGWMYTPGMPPFKPQYDTTLADACNALAQRWTKAKDADLSGFSEADI----KQLSSHQLIEFLALLLL-QVDPLPTSHVKRMQEVYKFNSINNSEIRCRWLRLCVKSEWEDAVPLALKMATEQGRMKFTRPLFRDVYNFAK--FRDEAVKVFKEHRNEMHSVTA 561          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIP---------IGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINL-NPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            + D  S+++    +T HL+     DF  +++ G V L ++ L  K + L LDTK L I KVS  G   +F++   +    GS L I          I IS +   V ++Y T+ + +ALQWL P  T GKKHPYLFSQCQA H R++ P                   Q ++ +   +  DPT + + +I++F Q V + SYL+A+V G L  +++  RS VWSE E V++ A EF +TE +L  AES+ G YVWG YDLLVLPPSFPYGGMENPCLTFVTPTLL        V+AHEI+HSWTGNLVTNKTWE FWLNEGHT Y+ER+I                         ++ +G  +    LV  L   +PD+ FS VPYEKG  LL+HLE + G  ++ + ++K Y + + Y S+TT++WK + + Y  DK +I    L+ VDW  W Y     P          DA   LA +W    + ++S   + D+    +    HQ   FL +L   +   L +  ++ M  +Y++ + +NSEI   W+ LC++S    A+         QGR+K+T+P++R++ N+     +   VK F ++ N MH +TA
Sbjct:    4 VTDHCSFSSFSKCLTRHLNLSLQADFSSRVLRGRVALTVEVLEDKFSSLTLDTKDLKIFKVSANGQAAKFEL-GAQHGFKGSPLDITLPFELSRLCIFISGQHVIVEVEYETSPSASALQWLSPAQTAGKKHPYLFSQCQATHCRTMVP---------------NLLTQTHIAVRDGQEADPT-DSSRVIYRFRQPVPMPSYLIALVVGALESREIGPRSRVWSEKEHVDQGAFEFTETETMLKTAESLAGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLL--------VIAHEISHSWTGNLVTNKTWEHFWLNEGHTVYLERMIGR-----------------------VHQFGANNAATNLVVNLEGVNPDECFSCVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQMFAYSSVTTEQWKDYLFTYFKDKVDI----LNKVDWNGWMYTPGMPPFKPQYDTTLADACNALAQRWTKAKDADLSGFSEADI----KQLSSHQLIEFLALLLL-QVDPLPTSHVKRMQEVYKFNSINNSEIRCRWLRLCVKSEWEDAVPLALKMATEQGRMKFTRPLFRDVYNFAK--FRDEAVKVFKEHRNEMHSVTA 559          

Query:  101 ALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDT-KYLDIKKVSVKGTE---TRFDIVDCKIEALGSCLKIPIGI---SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKIPV-DHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTT-SSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPN-DHIKRLTVKNFLKNENTMH 1909
            A +  D  + ++   +  EH   D  +DFD++ + G+ +L+++      A+L LD+   L++ +VS    E   T          + GS L +       S ++F + I+Y T      + WL PE T GK  PY+F+Q QA+  RS FPC D+P VKSTY+A +K P+ F  +MSA K E   K  N  +   EQ   I +YLVA+  G+L   ++  RS VW+EP ++E A  E+    E  L + E + G YVWG YD+L +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI HSW GNLVTN  W DFWLNEG T Y +R I ++ Y  E    L  + G A L++ ++  GE H  N+L V +    DPDD+++  PYEKG   + +L ++ G  +    +LK Y + +K++S+  ++   FF ++  D +  S  K++ +++  W     W + + D    +     +++LAD W   + +I+   +    +  E++  +Q  YFL  +   +++ L       +   Y +   S+N+E+   W  +  ++ H P    +  FL+ QG+ KYT P+YR L  W   + +K L  + F    + +H
Sbjct:   10 ADTAEDVATSSSFRRFRIEHFHLDLQVDFDQRSLSGTESLRVRCALGSAAELLLDSHPSLELHEVSFSRDERDWTAAQFHSRDFTSYGSTLVVQFPTAWSSGDQFHLSIKY-TAHQGPGVCWLDPEQTAGKLRPYVFTQGQAVLNRSFFPCFDTPAVKSTYTAAIKVPDGFTAVMSATKWEH-RKADNTFLFSMEQP--IPAYLVALAVGDLVSAEVGPRSRVWTEPCLLEAAKKEYDGVIEEFLLVGERLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEICHSWFGNLVTNANWGDFWLNEGFTMYAQRRICKELY-GEAYTCLEAATGRALLRQHMDNTGEDHPLNKLRVKIKPGVDPDDTYNETPYEKGFCFVSYLAHLRGDQKRFDAFLKAYVDRFKFRSVIAEDALEFFLEFFPDLKKNSVHKIEGLEFDSWLNVSGWPLYLPDLSAGQSLMKPADQLADLWGADSVDIAAISK----INTEAWKTYQTVYFLDKI--IEKSPLPDGNTRMLEEQYPHMVKSNNAELRLRWAQIVAKNQHKPGYPHVRSFLSCQGKQKYTLPVYRAL--WSGTEEMKALATEIFSATSHQLH 613          

Query:  101 ALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDT-KYLDIKKVSVKGTE---TRFDIVDCKIEALGSCLKIPIGI---SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADT-ENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQL-VPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQML-RWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF-YGRWKIPV-DHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTT-SSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYT 1816
            A +  D  + ++   +  EH   D  +DFD++ + G+ +L+++      A+L LD+   L++ +VS    E   T          + GS L +       S ++F + I+Y T      + WL PE T GK  PY+F+Q QA+  RS FPC D+P VKSTY+A +K P+ F  +MSA K E   K  N  +   EQ   I +YLVA+  G+L   ++  RS VW+EP ++E A  E+    E  L + E + G YVWG YD+L +PPSFP+GGMENPCLTFVTP LL GD+SL  V+ HEI HSW GNLVTN  W DFWLNEG T Y +R I ++ Y  E    L  + G A L++ ++  GE H  N+L V +    DPDD+++  PYEKG   + +L ++ G  +    +LK Y + +K++S+  ++   FF ++  D +  S  K++ +++  W     W + + D    +     +++LAD W   + +I+   +    +  E++  +Q  YFL  +   +++ L       +   Y +   S+N+E+   W  +  ++ H P    +  FL+ Q R  ++
Sbjct:   10 ADTAEDVATSSSFRRFRIEHFHLDLQVDFDQRSLSGTESLRVRCALGSAAELLLDSHPSLELHEVSFSRDERDWTAAQFHSRDFTSYGSTLVVQFPTAWSSGDQFHLSIKY-TAHQGPGVCWLDPEQTAGKLRPYVFTQGQAVLNRSFFPCFDTPAVKSTYTAAIKVPDGFTAVMSATKWEH-RKADNTFLFSMEQP--IPAYLVALAVGDLVSAEVGPRSRVWTEPCLLEAAKKEYDGVIEEFLLVGERLFGPYVWGRYDVLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEICHSWFGNLVTNANWGDFWLNEGFTMYAQRRICKELY-GEAYTCLEAATGRALLRQHMDNTGEDHPLNKLRVKIKPGVDPDDTYNETPYEKGFCFVSYLAHLRGDQKRFDAFLKAYVDRFKFRSVIAEDALEFFLEFFPDLKKNSVHKIEGLEFDSWLNVSGWPLYLPDLSAGQSLMKPADQLADLWGADSVDIAAISK----INTEAWKTYQTVYFLDKI--IEKSPLPDGNTRMLEEQYPHMVKSNNAELRLRWAQIVAKNQHKPGYPHVRSFLSCQVRRHFS 583          

Query:  500 QAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAI---KNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFW 1033
            QAIH RS+ PCQD+P +K TY AKV  P     LMSA+      DPT  G   +HKF+Q V I SYL+A+V G L  +++  R+ VWSE E VE+AA EF++TE +L+ AE + G YVWG YDLLVLPPSFPYGGMENPCLTFVTPT+L GDKSL  VVAHEI+HSWTGNLVTNKTWE FW
Sbjct:    1 QAIHCRSMVPCQDTPSLKFTYDAKVSVPKSLVALMSALCDGSEPDPTN-GEFTVHKFKQPVQIPSYLIALVVGALKSREIGPRTKVWSEKEFVEQAASEFSETETMLTTAEELVGPYVWGRYDLLVLPPSFPYGGMENPCLTFVTPTVLAGDKSLAGVVAHEISHSWTGNLVTNKTWEHFW 180          

Query: 1148 LNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLEN-ICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILF 1723
            ++ +G  H F +LVPVL   DPDDSFS VPYEKG  LL+HLE  + G D  + ++K Y E + Y + TT+EWKA+ ++Y  DK ++ +A    VDWK W Y     PV         D    LA +W         S   D L ++ S   +QK  FL +L       + S  ++ M  +Y+  +  NSEI F
Sbjct:    1 VDTFGPEHGFTKLVPVLDGVDPDDSFSTVPYEKGFALLYHLEQALGGPDVFIGFVKAYIEKFAYSTATTEEWKAYLFEYFKDKADVLQA----VDWKAWIYSPGMPPVKLQYDTTLADDCSALATRWSQAKDADLASFSADDLKDFSS---NQKVEFLALLLLQPALPVKS--LQRMEEVYKLNSVKNSEIRF 184          

Query:  467 GKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRS------TVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLLVGDKS--------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAE--LQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAF 1369
            G   P   +Q +   AR  FPC D P  K+++   +        L +   NE  T++   L   F+  V +S+YLVA +  +   K +SN++      ++++ P   ++ +    +    L   E +    Y     DL+ +P  F  G MEN   +T+    LL+G K+        +  V+AHE+ H W GNLVT   W D WLNEG   ++E +         L+  + ++  + E   Q+SL +    H  +      ++    + F  V Y KG+++L  L         +  ++ Y   + Y +  TD+ W++ 
Sbjct:  324 GSDRPLAVTQFEPTSARESFPCFDEPDFKASFDISIVRDAAHTTLSNMPLNETVTRKDGLLEDTFKGSVVMSTYLVAFIVSDF--KSISNKTKHGTNVSIYTSPGKEQQGSFALENAIKFLDFYEELFNISYPLPKQDLVAIP-DFAAGAMENWGLVTYRETALLLGPKASGVRDTLWVAQVIAHELAHQWFGNLVTMNWWNDLWLNEGFATFMEFVATGSLKPDWLMMDVFLTEVVMEALTQDSLPS---SHAISSAAVGTMQI--GEMFDSVSYNKGASVLNMLRTFLTPAVFVDGIRDYLLVHSYGNAHTDDLWESL 635          

Query:  458 ATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAP------NQFNVLMSAIKNEDPTKEGNHLIH-KFEQKVNISSYLVAIVCG--NLAGKKLSNRSTVWSEPEMVEKAAHEFA---DTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLLVGDKS--------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTT-DEWKAFFYKYMIDKENISKAKLDNV--DWKKWFYGRWKIPVDHVLKRDHGDA 1501
            A  G+      +Q +A  AR  FPC D P +K+T+   +  P      +  NVL       DP      L+  ++ +   +S+YL+A V G  +    + S+   V     + +    +FA    T+ L    +     Y     DL+ +   F  G MEN   +T+    LLV  K+        +  VV HE+ H W GNLVT + W   WLNEG   +IE L ++  +    I    +S   A   E L+A    H     VPV    + D+ F  + Y KG++++  L +  G +   + +  Y   +++K+  T D W++         E  S   +  V   W K    +   PV HV     G++
Sbjct:  122 AACGEARYAAVTQFEATDARRAFPCWDEPGIKATFDVTLIVPQDRVALSNMNVLERKPHEADP-----ELVEVRYARTPIMSTYLLAFVVGEFDFVEARSSDGVLVRVYTPLGKSEQGKFALEVATKTLPFYKDYFNVPYPLPKIDLIAIA-DFAAGAMENWGLVTYRETALLVDPKNSSSASKQWVALVVGHELAHQWFGNLVTMEWWTHLWLNEGFASWIEYLCVDHCFPEFDIWTQFVSTDYAPALE-LDALDNSHPIE--VPVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDEDFKKGMNMYLTKFQHKNAATEDLWESL--------EQASGKPVAAVMSSWTK----QMGFPVLHVYSEHQGES 472          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKV--KAPNQFNVLMSAIKNEDPTKEGNHLIH-KFEQKVNISSYLVAIVCGNLAG-KKLSNRS--TVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDL-LVLP-------PSFPYGGMENPCLTFVTPTLLV--------GDK-SLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVP---VLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKY-KSLTTDEWKAFFYKYMIDKENIS--KAKLDNVDWKKWFYGRWKI----PVDHVLKRDHGDASERLADKWINLNP 1540
            SQ +   AR  FPC D P +K+T+   +  KA +     M  +     T      +H KF   V + +YL+A +  +    + ++N++   +W++   +     E+A     L+I   I   +    YD+  VLP       P F  G MEN  L     T L+        G+K S+  +V HE+ H W GNLVT + W + WLNEG   Y+E +   +   S  I+ L+I   + +LQ +++           VP   V+     +  F  + Y KG+ +L    +   +   +  LK Y +  ++  ++  D W+    ++ +D   ++   A  D +D       RW I    PV HV       +S +L      LNP
Sbjct:  210 SQMEPTDARKTFPCFDEPDMKATFDITLIHKAEHVALSNMPVVYMSTATSIEEDWVHTKFNTSVVMPTYLLAFIISDFEKVEAVANKTLIRIWAKKTEIAAGNAEYA-----LNITGKILN-FFEEYYDVPYVLPKSDQIAIPDFAAGAMENWGLVTYRETALLYNPDVSSNGNKESVATIVTHELAHQWFGNLVTMRWWSELWLNEGFASYLEYIGTHEVEPSWNIKALII---LNDLQRAMSVDALASSRPLSVPHSEVMTPAQANSMFDTISYSKGACILSMTSSFLTEPVFVAGLKSYLKEMQFGNAVHQDLWRHL--QWAVDNHTVTLPVAVKDILD-------RWTIQMGYPVVHV-----NTSSGKLTQSHFLLNP 569          

Query:  116 DPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTK---KQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFA-DTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVE-CDPDDSFSRVPYEKGSNLLFHLENIC-GKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYES-----FLPHQKYYFLQVLN----------DFKEAKLHSKVIETMGNLYQ--YTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPI 1915
            D  + +N +D+   H D +  + F++  I GSV  QLK L +   K  +L LDT YLD+++V + G++  F I   K E LGS L I     ++ F++ IQ+ TT  CTALQWL  + T G K PY+FSQ +AIHARSLFPC D+P VKST++A +++P    V+ S I+ ED +K+ N  I++FEQKV I +YL+ I  G+L+   +  RSTV++EP  ++    EF  D E  +  AE I  EY WG YD+LV   S+PYGGME+P +TF TPTL+  D+S + V+AHE+ HSW+GNLVTN +W  FWLNEG T Y+ER I+   +  E  RH    IG ++LQ S+++  +  +F+ LV  L +  DPDD+FS VPYEKG NLLFHLE I  GK +   +++ YF+ +  KSL T ++    Y++  +K+ I    LD+VDW+ W Y     P  H +     D   +LADKW+ +   +  ++  D   E+ +     F  +Q   FL+ L           DF  AK        + ++YQ     S N+E++F      I +        + D+L + GR+K+ +P YR L    N   +RL +  F K ++T HPI
Sbjct:   57 DQSTLSNYKDFAVLHTDLNLSVSFEKSAISGSVTFQLKKLHEGKNKSDELHLDTSYLDVQEVHIDGSKADFQIEQRK-EPLGSRLVINNASCNDNFTLNIQFRTTDKCTALQWLNSKQTKGGK-PYVFSQLEAIHARSLFPCFDTPSVKSTFTASIESP--LPVVFSGIRIEDTSKDTN--IYRFEQKVPIPAYLIGIASGDLSSAPIGPRSTVYTEPFRLKDCQWEFENDVEKFIQTAEKIIFEYEWGTYDILVNVDSYPYGGMESPNMTFATPTLIAHDRSNIDVIAHELAHSWSGNLVTNCSWNHFWLNEGWTVYLERRIIGAIH-GEPTRHFSALIGWSDLQNSIDSMKDPERFSTLVQNLNDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEFDPFIRHYFKKFAKKSLDTFQFLDTLYEFYPEKKEI----LDSVDWETWLYKPGMPPRPHFITA-LADNVYQLADKWVEMAQHLKTTE--DFRSEFNAIDIKDFNSNQLVLFLETLTQNGHSNKKPKDFDWAKF-PVASRALLDIYQDNIVKSQNAEVVFKMFKFQIFAKLQEEYKHLADWLGTVGRMKFVRPGYRLL----NSVDRRLALATFDKFKDTYHPI 660          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRST---VWSEP--EMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLL--VGDKSL------VFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYI----------ERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTT-DEWKAF 1369
            +Q +A  AR  FPC D P +K+T++  + + +    L +     +  KEG      F     +S+YLVA +  +L   + +N      V+S P  E   + A   A    L    ++   EY     D++ +   F  G MEN   +T+    LL  + + SL        V+ HE+ H W GNLVT   WE  WLNEG   ++          E  + E+Y    L R L           +L++    H     VPV    + +  F  + Y KGS+LL  +    G++  ++ +  Y   +KY +  T D W A 
Sbjct:  129 TQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGKKYT-TFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLA-ARTLRFFEDTFNIEYPLPKMDMVAVH-EFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRAL-----------NLDSLRSSHPIE--VPVNNADEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDAL 430          

Query:  140 EDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIG-ISDEKFSVCIQYATTA----NCTALQWLIPEATVGKKHPYLFS-QCQAIHARSLFPCQDSPCVKSTYSAK-VKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLA---GKKLSNRSTVWSEPEMVEKAAHEFAD-TENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMENPCLTF--VTPTLLVGDKS-------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYI----------ERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTT-DEWKAF 1369
            ++ V  H D     DF     EGSV ++LK        + L+T   DI    + G  T  +I+  + E   +    P G +S  K +  +    T     N         E  +  +  Y+ + Q +   AR  FPC D P +K++++   V  P+  ++    +KNE   K+G   +  F     +S+YLVA +   L     K       V++ P   EK     AD T   L+  E   G +Y     D + +   F  G MEN  L    V   LL  D S       +  VV HE+ H W GNLVT   WE  WLNEG   ++          E  + E+Y  ++ ++H L          SL++    H     VPV    + +  F  + Y KG++LL  +    G++  ++ +  Y   +KY +  T D W A 
Sbjct:  104 DNVVPLHYDLTVEPDFKTFKFEGSVKIELKINNPAIDTVTLNTVDTDIHSAKI-GDVTSSEII-SEEEQQVTTFAFPKGTMSSFKGNAFLDIKFTGILNDNMAGFYRAKYEDKLTGETKYMATTQMEPTDARRAFPCFDEPNLKASFAITLVSDPSLTHLSNMDVKNE-YVKDGKK-VTLFNTTPKMSTYLVAFIVAELKYVESKNFRIPVRVYATPGN-EKHGQFAADLTAKTLAFFEKTFGIQYPLPKMDNVAVH-EFSAGAMENWGLVTYRVVDLLLDKDNSTLDRIQRVAEVVQHELAHQWFGNLVTMDWWEGLWLNEGFATWMSWYSCNEFQPEWKVWEQYV-TDTLQHAL----------SLDSLRSSHPIE--VPVKKADEINQIFDAISYSKGASLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTEDLWDAL 526          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQF----NVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNL----AGKKLSNRSTVWSE---PEMVEKAAHEFADTENLLSIAESICGEYVWGIYDL----LVLPPSFPYGGMEN-PCLTFVTPTLLVGDKSLV---------FVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEK------YYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYK 1333
            + CQ   A ++FPC D P  KST+   +    Q+    N  +  ++  D +++  HL+ KF +   +++ +     G+L       KL    T+      P  +  AA      +  L + ES    Y    Y L     VL P      MEN   +T     LL+   +L           ++ HE+ H W GN ++  +WE  W NE    ++   I+E+      Y+ SE   +LL  +     +++ +  G            ++    D F    Y KG  +L  L+   G+  + + L+  FE  K
Sbjct:  152 THCQPFSASNIFPCIDEPSNKSTFQLNIATDAQYKAVSNTPVEMVEALDSSQK--HLV-KFAKTPLMTTSVFGFSIGDLEFLKTEIKLEGDRTIPVSIYAPWDIANAAFTLDTVQKYLPLLES----YFKCPYPLPKLDFVLLPYLSDMAMENFGMITIQLNHLLIPPNALANETVREQAQQLIVHELVHQWMGNYISFDSWESLWFNESFATWLACHILEQNGDLSHYWTSE--PYLLQQVEPTMCRDAADVNGRSIFQIAQRNTGIDSQTSDIFDPEAYTKGIIMLRSLQLATGESHLQKGLESVFEDTK 454          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDI-VDCKIEALGSCLKI--PIGI-SDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIK--NEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDH--GDASERLADKWINLN-PEISDSDQKDLLLEYESFLPHQKYYFL-QVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            ++DP S++  E+ +  ++ ++  +DF  K++   V L         A L LDT+ L+++ V+V+ +  +    +  K +A G+ L+I  P G+ S  + S+ I Y T+ + +ALQWL PE T GKKHPY+F+QCQAIHARS+ PCQDSP VK+TYSAKV  P     LMSA +  +E   ++ + + ++FEQKV I SYL+A+V G L G+++  RS VW+E EMVE+ A+EFA+ E ++S AES+ GEYVWG YDLL+LPPSFPYGGMENPCLTFVTPTLL GD+SL  V+AHEI+HSWTGNLVTN TWE FWLNEG T ++ER I+ +    E +R      G   L ++++ + +     +LV  L + DPDD+FS VPYEKGS  L +LE + G  ++   + + Y + YKYK+ TTDEWK F + Y  DK NI    L+ VDW+ W       PV+ + + D    DA   L  KWIN +  E++    +D+     SF   QK  FL Q+L     + L    ++ M N YQ+ +  NSEI F W+ LC+RS    A     DFL SQGR+K+T+P+Y  L  +  +  K L V  F K+    HPI +  +
Sbjct:    1 MSDPCSFSRPEECLCTNITWNVSVDFASKVLVCDVELDFLVKKDNVASLVLDTRDLNVQSVAVRPSNDQLTFSLGSKHKAFGTPLEISLPPGLKSGARLSIAISYRTSPDASALQWLTPEQTSGKKHPYMFTQCQAIHARSIIPCQDSPGVKATYSAKVSVPKDLVALMSAARTGSELDHQKQDLMTYQFEQKVAIPSYLIALVVGALKGRQVGPRSHVWTEQEMVEECAYEFAEMEQMISAAESLVGEYVWGPYDLLILPPSFPYGGMENPCLTFVTPTLLAGDRSLTGVIAHEISHSWTGNLVTNSTWEHFWLNEGFTVFLERKIIGR-MKGEQMRQFGFIGGWKTLMDAVSKFADNMSLTKLVVSLKDTDPDDAFSSVPYEKGSCFLVYLEQLLGGPEVFEPFFRKYIDTYKYKTCTTDEWKTFLFDYFKDKTNI----LETVDWEAWLRKPGMPPVNMIERYDSSLADACISLCQKWINASEKELNSFSSQDI----ASFTSPQKVEFLAQLLAKTSSSPLSVAHLQAMQNAYQFNSYKNSEIKFRWLRLCVRSGWADAFQPTVDFLLSQGRMKFTRPLYEEL--FKCEKSKDLAVTTFKKHRAFYHPICSAMV 607          

Query:  398 VCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSA-----IKNEDPTKEGNHLIHKFEQKVNISSYLV---------AIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFAD-TENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYD----------------SELIRHLLISIGIAELQESLNAYGEGHKFN---QLVPVLVECDP---DDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDK-ENISKAKLDNVDWKKWFYGRW----KIPVDHVLKRDHGDASERLA---------DKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFL 1789
            V I+Y T+    +L W    AT     P +FS    I+ RSL PCQ+ P   ST+ A +  P+    LMS            T +G +         +  +  V         + +C    G        + + P ++++A+ E        +  +  + G Y +   DLL+LP  F   G++NP L F++ ++L GD S+   VAHEI+H+W G L+  K W + WL+EG + YIE  I  +                    +L+R+  +S  + E  E+L         +   +  P  V  +       +++V Y KG  LL H+  + G +   R+L  Y +HY+ + +T+++    F++Y + K  N+S++  D       F+  W     +P     K+ +   +  +A          K  N+N      + K         L H +   L +    +   L    +  +   Y ++T  N EI   W  L +++  TP +D +  FL
Sbjct:   19 VVIKYHTSPEGQSLSW----ATDQDGRPCVFSPGAYINNRSLMPCQEPPIAMSTWQAAIHVPHGCMALMSGNPVTMETTATDTDKGRYCTMDVPLPCSTLAMAVGYFESMEGRSAICPTKDGPAEPVECRMIAVPSIIDRASDELLSYVPGFIEASCELLGPYPFSRLDLLILPKCFACMGLKNPNLVFLSQSVLAGDGSIRVRVAHEISHAWFGLLIGAKDWTEEWLSEGFSTYIEERIQARAEKVNPGCAKKKNNSLRELRQLLRYRALSAEMDETDENLQCLRSRASLSPNEEAKPFTVVKNGQICSKKWTQVHYLKGYFLLHHMAAMVGLENFERFLYEYVQHYQGQLVTSED----FFQYFVCKFPNVSQSVKDE------FFLEWLESPGLPKCLRSKKFNVKENALIAAALKQFEFWRKQDNINKRNKTMNIKRRKQPEAEPLEHSEQIVLMLEKLVERDALMHTTLRQLNRCYNFST-RNCEIRHRWCELVVKNKFTPFLDDVKHFL 518          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKL----SNRSTVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLL-------VGDKS-LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYY-DSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAF 1369
            +Q ++  AR+ FPC D P  K+ +   +        + +  +++    +  +++ +F+Q V +S+YLVA +  +    +       +  VW++ E ++      +  +N+LS  E      Y     DL+ +P  F  G MEN   +TF    LL         DK  +  VV+HE+ H W GNLVT K W D WLNEG   Y+E +  + +  D +++   +       LQ  +++    H  +  VPV       + F  + Y KGS+++  L N  G     + L+ Y + + Y +   D+ W+A 
Sbjct:  133 TQFESTDARAAFPCFDEPEFKAVFVISMIHEKGMRAISNMPQSKRVQMDDGNVLTRFKQSVKMSTYLVAFIVSDFESTEAETPNGTKVRVWAQKEALDSTKLALSVAKNVLSYYEKFFNIPYPLPKIDLVAVP-DFAAGAMENWGLMTFREHYLLSNPLSASAADKQDVAIVVSHELAHQWFGNLVTMKWWNDLWLNEGFANYVEYMGTDHFAKDWKVLDQFVSETHQVALQ--VDSMANTHPIS--VPVTNPSQITEIFDAISYNKGSSVIRMLRNFLGDKAFQKGLEHYLKKHAYGNAEADDLWQAL 436          

Query: 1148 LNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR-WLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDH--GDASERLADKWINLN-PEISDSDQKDLLLEYESFLPHQKYYFLQVL 1627
            ++ + +     +LV  L + DPDD+FS VPYEKGS  L +LE + G  ++   + + Y + YKYK+ TTDEWK F + Y  DK NI    L+ VDW+ W       PV+ + + D    DA   L  KWIN +  E++    +D+     SF   QK  FL  L
Sbjct:    1 MSKFADNMSLTKLVVSLKDTDPDDAFSSVPYEKGSCFLVYLEQLLGGPEVFEPFFRKYIDTYKYKTCTTDEWKTFLFDYFKDKTNI----LETVDWEAWLRKPGMPPVNMIERYDSSLADACISLCQKWINASEKELNSFSSQDI----ASFTSPQKVEFLAQL 156          

Query:  512 ARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVA-IVCGNLAGKKLSNRST---VWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSL---------VFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERL-IMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAF 1369
            AR+ FPC D P +K+ ++  +    +   L +    E    E   +I  FE  V +S+YLVA +VC   + +  + R T   VW+  + +++  +  ++   +LS  E      Y     DL+ +P  F  G MEN  L     T L+ D  +           VVAHE+ H W GNLVT K W D WLNEG   ++E + +     +  ++   L+     +L  +L+     H  + +V    E   +  F  + Y+KG+ ++  L++  G D   + L+ Y   +K+ +  T++ W AF
Sbjct:  144 ARAAFPCFDEPALKAVFNMVIYRKAEHVSLSNMPIKE---TESGQVIDVFEPSVKMSTYLVAFVVCDFKSKEATTKRGTLVRVWAPEDNIDEGDYALSEAVKILSYYEKFFAVRYPLPKQDLIAIP-DFAAGAMENWGLITYRLTSLLYDPEVSSDSNKQWVAVVVAHELAHQWFGNLVTMKWWNDLWLNEGFASFVENIGVNHTTPEWRMMEQFLLD--KTQLSMNLDQLSNSHPISVVVKDPAEI--NSLFDTISYDKGAAIIRMLKSFLGDDVFQKGLQKYLNKHKFGNAETNQLWDAF 437          

Query:  110 LNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKI--PIGIS-DEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKN---EDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQM-LRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE----ISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITA 1921
            ++DP S+++    VT+HL+    +DF R++I G+V L ++ L    + L LDT+ L++  VS      RF +   K    G+ L I  P  +S  +   V + Y T+ + +ALQWL PE T GKK PYLFSQCQA H RS+ PCQD+P VK TY A+V  P     +MSA+++   EDP ++ + ++++F Q V + SYL+AIV G L  +++  RS VWSE E V+KAA EF++TE +L  AE + G YVWG YD+LVLPPSFPYGGMENPCLTF TPTLL GDKSL  V+AHEI+HSWTGNLVTNKTWE FWLNEGHT Y+ER+I  + Y  E  R      G  +LQ+S+N +G  +    LVP L + DPDD+FS VPYEKG  LL+HLE + G  ++ + ++K Y + Y Y S+TTD+WK + + Y  D+       L+ VDW  W +     PV         DA   L+ +W     +     S+SD K L         HQ   FL +L    E  L    ++ M  +Y   T +NSEI F W+ LC+RS    A+         QGR+K+T+P++R + N+  +  +   V+ F  +   MHP+TA
Sbjct:    1 MSDPCSFSSPSRCVTKHLNLHLRVDFRRRVIAGTVELTVEALEDNFSLLTLDTRDLNVVSVSANQQPARFTLAS-KHSFKGTQLDITLPFHLSRGQHVIVQVVYETSPSASALQWLTPEQTAGKKQPYLFSQCQAHHCRSMVPCQDTPSVKHTYYAQVSVPKDLVAVMSAVRDGQEEDP-EDSSRIVYRFRQPVPMPSYLIAIVVGALESREIGPRSRVWSEKEFVDKAAFEFSETETMLKTAEDLAGPYVWGQYDILVLPPSFPYGGMENPCLTFATPTLLAGDKSLSTVIAHEISHSWTGNLVTNKTWEHFWLNEGHTVYLERMIGRQMY-GEQFRQFKAMGGWKDLQDSVNTFGPNNPLTNLVPSLQDVDPDDAFSSVPYEKGFALLYHLEELMGGPEVFMGFVKSYIQLYAYGSVTTDDWKNYLFTYFKDQAE----ALNRVDWNAWMFTPGMPPVKPQYDTTLADACIALSQRWTKAGDQDLDGFSESDVKTL-------SSHQLIEFLSLL--LHENPLPLTHVKKMQEVYGLNTCTNSEIRFRWLKLCVRSKWEEAVPLALKMATEQGRMKFTRPLFREVFNF--NKYRDEAVQVFAAHRTAMHPVTA 597          

Query:  467 GKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQ-KVNISSYLVAIVCGNLAGKKLSNRST---VWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLLVGDKS-------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR 1303
            G KH    +Q + + AR  FPC D P  K+T+  K+     +  L +  ++E           +FE+  VN+S+YLVA V  N +  + +   T   V+S PE  E   +       LL    +    +Y     DL+ +P  F  G MEN   +TF   TLLVG  S       +  VVAHE+ H W GNLVT + W D WLNEG   Y++ L +++ +       L +S+    + +  +A    H  +    V+     ++ F  V YEKG+++L  L      +Q  R
Sbjct:  293 GTKHILAATQFEPLSARKAFPCFDEPAFKATFLIKINRKQNYTTLSNMPQSESRLLPSGLFQDEFERTSVNMSTYLVAFVVANFSAVRKNVSETLVSVYSVPEKTEHTRYALEAASKLLEFYNTFFDIDYPLKKLDLVAIP-DFLAGAMENWGLITFRETTLLVGKDSSPLEKQVVASVVAHELAHQWFGNLVTMRWWNDLWLNEGFATYMQYLSLQRVFPELQAEILFLSVRFRVMDK--DALISSHPVS--TAVVTPDQVEEMFDSVSYEKGASILLMLNAYLPGEQQFR 579          

Query:  467 GKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQ-KVNISSYLVAIVCGNLAGKKLSNRST---VWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLLVGDKS-------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLR 1303
            G KH    +Q + + AR  FPC D P  K+T+  K+     +  L +  ++E           +FE+  VN+S+YLVA V  N +  + +   T   V+S PE  E   +       LL    +    +Y     DL+ +P  F  G MEN   +TF   TLLVG  S       +  VVAHE+ H W GNLVT + W D WLNEG   Y++ L +++ +       L +S+    + +  +A    H  +    V+     ++ F  V YEKG+++L  L      +Q  R
Sbjct:  292 GTKHILAATQFEPLSARKAFPCFDEPAFKATFLIKINRKQNYTTLSNMPQSESRLLPSGLFQDEFERTSVNMSTYLVAFVVANFSAVRKNVSETLVSVYSVPEKTEHTRYALEAASKLLEFYNTFFDIDYPLKKLDLVAIP-DFLAGAMENWGLITFRETTLLVGKDSSPLEKQVVASVVAHELAHQWFGNLVTMRWWNDLWLNEGFATYMQYLSLQRVFPELQAEILFLSVRFRVMDK--DALISSHPVS--TAVVTPDQVEEMFDSVSYEKGASILLMLNAYLPGEQQFR 578          

Query:  512 ARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDP-TKEGNHLIHKFEQKVNISSYLVAIVCGNLA-GKKLSNRST---VWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLP----PSFPYGGMEN-PCLTFVTPTLLVGDKS--------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSL-TTDEWKAF 1369
            AR  FPC D P  K+TY+  +     +  L +  +   P    GN L   F++ V +S+YLV          +K+S R     ++++P  +  A  EFA   N   +      EY    Y +  L     P F  G MEN   +T+    LL  D+         +  V+AHE+ H W GN+VT   W+D WLNEG   + E + +EK   S  +R ++I   +  +  + +A    H    +V V    +    F  + Y KG+++L  LE+  G+D      + Y + + +K+  T D W + 
Sbjct:  228 ARKSFPCFDEPNKKATYNISITHHKDYRALSNMPQEGQPEVLPGNKLKTSFQKSVPMSTYLVCFAVHQFEFVEKISKRGIPLRIYAQPSQLGTA--EFA--ANTTKVIFDYFEEYFDMFYSISKLDQIAIPDFGTGAMENWGLVTYRETNLLYDDRESSSSNKQRVASVIAHELVHQWFGNIVTMDWWDDLWLNEGFASFFEYIGVEKAEPSWGMRDIMIISDVLPVMVN-DALLSSHPI--IVDVSTPAEITSVFDAISYSKGASVLRMLEDWMGRDAFRDGCRKYLKDFYFKNAKTADFWASL 525          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMS-AIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTV----WSEPEMVEKAAHEFA--DTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMENPCLT-FVTPTLLVGDK--------SLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERL---IMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPE---ISDSDQKDLLLEYE 1585
            +Q   IHAR  FPC D P  K+T+S  ++   Q+  L +  ++    + E   + ++F +   +S+Y +A    N   ++    S V    ++ P+ +   A ++A   T+ LL   E     +Y     DLL +P   PY  MEN  L+ FV   +L+  +         L  VV HEI H W G+LVT   WED WL EG   + E +    +   ++ E  R L   +    L + L++    H  +Q   V    D D  F  + Y+KG+ L+  L N+ G+    + L  Y   + Y +   D+ W         +  +I+  ++ +         RW + + + +     + SE+    +I +N +     +  +K+L L+++
Sbjct:  246 TQFSPIHARKAFPCFDEPIYKATFSLTLRHDPQYISLSNMPVEASSLSDEDGWVTNRFARTPRMSTYYLAWAVCNFTYRETQTDSGVTIRLYARPDAISSGAGDYALHITKRLLGFYEDYFKVQYSLPKLDLLAVP-KHPYAAMENWGLSVFVEQKILLDAEVSSSSYQMELTMVVVHEICHQWFGDLVTPVWWEDVWLKEGFAHFFEYVGTDFLFPKWNMEKQRFLTDVLHEVMLLDGLSS---SHPISQ--EVERATDIDRVFDWIAYKKGAALIRMLANVMGQPLFQKGLNDYLLSHMYSNAARDDLWSKLSQAMHSEGRDINIGEMMD---------RWTLQMGYPVVTISKNQSEQRPTHYITINQKHFLYGEEARKNLSLQWQ 619          

Query:   98 MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQV 1624
            MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKD                                              WKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQV
Sbjct:    1 MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKD----------------------------------------------WKKWFYGRWKIPVDHVLKRDHGDASERLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQV 463          

Query:   98 MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWF 1444
            MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKK F
Sbjct:    1 MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPIGISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKGF 449          

Query:   98 MALSLNDPVSYANSEDYVTEHLDFDWIIDFDRKLIEGSVNLQLKNLTKKQADLKLDTKYLDIKKVSVKGTETRFDIVDCKIEALGSCLKIPI--GISDEKFSVCIQYATTANCTALQWLIPEATVGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESICGEYVWGIYDLLVLPPSFPYGGMENPCLTFVTPTLLVGDKSLVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNA----YGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDEWKAFFYKYMIDKENISKAKLDNVDWKKWFYGRWKIPVDHVLKRDHGDASE--RLADKWINLNPEISDSDQKDLLLEYESFLPHQKYYFLQVLNDFKEAKLHSKVIETMGNLYQYTTSSNSEILFGWVMLCIRSNHTPAIDQIFDFLNSQGRLKYTKPIYRNLANWPNDHIKRLTVKNFLKNENTMHPITAKSI 1930
            M  S ND  SYANSED++ +   F+W +DF+ + I GSV   +K L     +L LD + L+IK++ +   +  F  V+ K   LG  L IP+  G    KF V I+Y TT + TALQW+ PE T+GKKH +L+SQ QAI+ARSL+PCQD+P VK+TYSA ++AP+   V+MSA++ +  T   +   HKFEQK+ I SYLV+I CG+L G K+  RSTV+SEPE+ EKA  EF D E +L IAE +CG Y W I DLL+LPPSFPYGGMENPC+ F+TP LL GDKS +  +AHEI+HSWTGNLVTN TW+ FW+NEGHT Y+ERLI+EK   SE  RHL I +GI+EL+  LN     YG  H+F +LVP L   DPDDSFSRVPYEKGS LLF+LE + GKD+MLRWLK Y   ++ KS++TDEWK FF+KYMI+KE +  +KL+ + W  WFY    IP++H    D     E   L   WI  +     S + +LL  +   LP Q+YYF QVLN+ +  +L    ++ MGN+Y  T ++NSE+L GW +LC+RS++ PA+DQ+F+FLNSQGRLKY K +Y++L +W  D  K  TV+NF   +  MHPIT   I
Sbjct:    1 MEFSQNDKTSYANSEDFIVDKSHFNWKLDFENEQISGSVVHNVKVLNSASKELILDVRNLEIKRIVIDNEDVLFQYVNGK---LGGKLVIPLSLGTKRSKFQVIIEYNTTNDSTALQWMKPEMTMGKKHSFLYSQSQAINARSLYPCQDTPFVKTTYSATIEAPSDLEVVMSAVR-KSSTLSNDVRQHKFEQKIPIPSYLVSIACGHLVGSKIGPRSTVYSEPELNEKARLEFEDIEKILVIAEELCGPYEWEICDLLILPPSFPYGGMENPCIIFLTPCLLTGDKSQLNYIAHEISHSWTGNLVTNSTWDHFWVNEGHTNYLERLILEKLQSSEPYRHLHIYLGISELEGDLNMYQIIYGPDHEFTKLVPNLHGKDPDDSFSRVPYEKGSLLLFYLETLIGKDKMLRWLKTYIAAFRLKSVSTDEWKTFFFKYMIEKEKVEPSKLEGIKWDDWFYKPGPIPIEHHSLLDDSMIQECNELVKAWIGFHQ--FPSSENELLNRFSRMLPDQRYYFFQVLNEIQGVQLPESSLKVMGNIYGLTNTTNSELLHGWSLLCLRSHYMPAVDQVFEFLNSQGRLKYNKVLYKHLYDW--DDTKSRTVENFHIQKFAMHPITRGEI 611          

Query:  464 VGKKHPYLFSQCQAIHARSLFPCQDSPCVKSTYSAK-VKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCG-----NLAGKKLSNRS--TVWSEPEMVEKAAHEFADTENLLSIAESICG-EYVWGIYDLLVLPPSFPYGGMEN-PCLTFVTPTLLVGDKS--------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSE--LIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYKSLTTDE-WKAF 1369
             G +   + +  +   AR  FPC D P  K+ +S + V+  +  ++    +++ +    G +    +E  V +S+YLVA +       +L G    N++   +++  +  +  +      + +L   E++ G +Y     D++ +P  F  G MEN   +T+   TLL+  KS        +  +++HEI H W GN+VT   W D WLNEG   Y E L  + Y + E  +I H  +   +  L  + ++    H     VPV    + +  F ++ Y KG++L+  LE + G + +   LK Y + Y+Y++  +D  W AF
Sbjct:  217 TGVEKTLITTHMEPTFARQAFPCFDEPYFKANFSLRMVRDKDHHSLFNMPLRSTEKLANGLY-CDSYETSVKMSTYLVAYMLLPLDYISLDGYASLNKTKIRIYAPKDQKDYTSFALEIAQKVLPFFENLFGIDYPLPKLDMIAIP-DFSAGAMENWGLITYKFFTLLLNPKSPKIQHKTSIAKIISHEIAHQWFGNIVTMDWWNDLWLNEGFATYSEYLAGD-YINREWGMIGHFYLEQFVDAL--NFDSLLNSHPIQ--VPVKDPQEIESIFDQISYGKGASLVRMLEGVLGLETLKVGLKIYLQRYRYQTAVSDNLWTAF 532          

Query:  491 SQCQAIHARSLFPCQDSPCVKSTYSAKVKAPNQFNVLMSAIKNEDPTKEGNHLIHKFEQKVNISSYLVAIVCGNLAGKKLSNRSTVWSEPEMVEKAAHEFADTENLLSIAESIC-------GEYVWGIYDL----LVLPPSFPYGGMENPCLTFVTPTLLVGDKS---------LVFVVAHEITHSWTGNLVTNKTWEDFWLNEGHTRYIERLIMEKYYDSELIRHLLISIGIAELQESLNAYGEGHKFNQLVPVLVECDPDDSFSRVPYEKGSNLLFHLENICGKDQMLRWLKCYFEHYKYK-SLTTDEWKAF 1369
            +Q +A  AR  FPC D P +K+T+   +  P     L +  +       G+ +  ++E+   +S+YL+A V G L   +  + + V           +   D  N    A  +C         Y   +Y L    LV  P F  G MEN  L     T+L+ D+          +  VV HE  H W GNLVT   W D WLNEG   +IE L ++  Y    I     S   A    +L+A    H     V V    + D+ F  + Y KG+ ++  L +    ++  + L  Y + ++Y+ ++T D W A 
Sbjct:  126 TQFEASDARRAFPCWDEPNIKATFDITLVVPKTKTALSNMPEKCRTEVSGSLVKIEYEKSPIMSTYLLAFVIGELDYVESHDSNGV-------RVRVYTAKDKSNRGRFALDVCCRTLPFYATYFDIVYPLPKMDLVAIPDFAAGAMENWGLVTYRETMLLVDEHESSSLSKQIVALVVGHECAHMWFGNLVTMDWWTDLWLNEGFATWIEYLCVDYCYPEFDIWTNFSSDEYARAL-NLDALRSSHPIQ--VTVHKPSEIDEIFDAISYSKGACVIRMLNDYLTNEKFKKGLSIYLKRHRYQNAVTADLWAAL 429