Metabotropic glutamate receptor

Overview
NameMetabotropic glutamate receptor
Smed IDSMED30025806
Length (bp)3388
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Metabotropic glutamate receptor (SMED30025806) t-SNE clustered cells

Violin plots show distribution of expression levels for Metabotropic glutamate receptor (SMED30025806) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Metabotropic glutamate receptor (SMED30025806) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Metabotropic glutamate receptor (SMED30025806) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30025806

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30025806h1SMcG0006658 SmedASXL_014586SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30025806h1SMcG0006658 dd_Smed_v4_15419_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025806h1SMcG0006658 dd_Smed_v4_15419_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30025806h1SMcG0006658 dd_Smed_v6_15419_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
head regionSMED30025806h1SMcG0006658 OX_Smed_1.0.10343ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Match: GRM3 (glutamate metabotropic receptor 3 [Source:HGNC Symbol;Acc:HGNC:4595])

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 369/859 (42.96%), Postives = 519/859 (60.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG------NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV 2728
            GD++LGGLFP+++  + TE C +IN DRGIQRLEAMLF I EIN    +LP + +G  ILDTCS+DTYAL+QSL+F+++SL+  ++A +Y C D S  ++       I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  + +     ++++ L Q+    RVVVLF R D ++ L+ A    N S  F W+ASDGWG +   +  + +VA GAIT E+ +  ++ F  YF  L    N  NPWF ++WE+ F C               SL                 NK+N    HR              ++C   + +    N++QESKI  V +AVYA+A+ L + Q  LC P   + C  A+  +DG   YKD L+  +FT  +       ++V FD+ GD +G+YN++N+      GKY Y  +G +        + + W      +P S CS+ C   +++       CCW C  C+  EY+ +   C  C  G+WP  + TGCY L   Y++     AI P+ ++ LG   T  V+ VF  + NTP+V+ASGREL +++L G  + Y ++F F+ KP+P  CA++R+ LG  FA+ Y++LLTKTN IARIF+  +  A+RP  ISP SQ+ IC  LI VQ++  ++WL    PG R     +K E  +LKC ++  + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L CLF PK+HII  QP+KNV
Sbjct:   37 GDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEA-EYMCPDGSYAIQENIPLL-IAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PNARVVVLFMRSDDSRELIAAASRANAS--FTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC---------------SLQ----------------NKRN----HR--------------RVCDK-HLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLC-PNTTKLC-DAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNF--QNVGGKYSYLKVGHWAETLSLDVNSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNV 834          
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Match: GRM2 (glutamate metabotropic receptor 2 [Source:HGNC Symbol;Acc:HGNC:4594])

HSP 1 Score: 664.455 bits (1713), Expect = 0.000e+0
Identity = 378/879 (43.00%), Postives = 506/879 (57.57%), Query Frame = 2
Query:  182 NGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSG 2782
             GD++LGGLFPVH      E C  +N  RGIQRLEAMLF +  IN  P +LP + +GA ILD+CSKDT+AL+Q+LDF+++SLS   D S + C D S    H  A   I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF  E++   +C+A  E +      +    +V+ L Q+ S  RV VLFTR +  + LL A + +N S  F W+ASDGWG     V  +   A GAIT E+ +  I +F +YF  L    NS NPWF E+WE         Q+ R S                         +Q   + H                       S +   F+QESKI  V +AVYA+A+ L      LC P     C  A+  ++G   YKD + N   D+        N V FD  GD +G+YNI+ Y+R   +G+Y Y+ +G +  +GL L+ S + W       +P S CSE C   +++       CCW C  C+  EY ++   C  C  G WP  + TGC+ L   Y++     A+ P+ ++ LG   T  V+GVF  +  TP+V+ASGREL +++L G  +CY ++F+F+ KP+   C ++R+ LG  F+V Y++LLTKTNRIARIF  A++ A+RP  ISP SQ+ IC  LIS QLL    WL    PG   +   ++ E   L+C     + L SL YN+LLI++CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ +SVSLS  V L CLF PKLHII  QP+KNV        ++R PT+  G
Sbjct:   29 EGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYAT-HGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPS-ARVAVLFTRSEDARELLAASQRLNAS--FTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWE---------QRFRCS------------------------FRQRDCAAH-----------------------SLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALC-PNTTRLC-DAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLR-AGSGRYRYQKVG-YWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNV-------VSHRAPTSRFG 836          
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Match: GRM8 (glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 363/887 (40.92%), Postives = 503/887 (56.71%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVHDSETE--LCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKK-----PEFP--VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C ++  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L      LC P  +  C + ++ IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y I NK T    YK IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC L+ +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +R+ LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP I  D  +     PE    VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC-PGYIGLCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKST---EYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Match: GRM8 (glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 363/887 (40.92%), Postives = 503/887 (56.71%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVHDSETE--LCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKK-----PEFP--VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C ++  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L      LC P  +  C + ++ IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y I NK T    YK IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC L+ +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +R+ LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP I  D  +     PE    VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC-PGYIGLCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKST---EYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Match: GRM8 (glutamate metabotropic receptor 8 [Source:HGNC Symbol;Acc:HGNC:4600])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 363/887 (40.92%), Postives = 503/887 (56.71%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKK-----PEFP--VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C ++  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L      LC P  +  C + ++ IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y I NK T    YK IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC L+ +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +R+ LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP I  D  +     PE    VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC-PGYIGLCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKST---EYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 340/926 (36.72%), Postives = 502/926 (54.21%), Query Frame = 2
Query:  185 GDIILGGLFPVHDSE---TELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEV-LRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFS-KTRVVVLFTRLDHTKLLL----NAVKIMNYSN-YFLWIASDGWGQENGPVTNNSN--VANGAITFEVKTVEIKNFTTYFHQLTYNRNS--NNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-----------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNY----------IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGW---LAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL---TMSSTTYRKPTNSSGSF-ANHREMNSEYTPL 2827
            GDI++GG+FPVH       E C +I   RG+ R+EAML+ + +IN++ D L    +GA ILD+CS   YAL QSLDF++  +  +++ASDY C D S+  L+     + +  VVGGSYSSVS+ +ANLLRLF I Q+S AST+A LS+K     FART+PSD  QA AM E+   F W+YVS V S+ +YG+ G DAF KE++K G+CIA +E I  K       +  +V+ L  E +    VVVLF   ++   +L      +K+ + +    +W+AS+ W + N   T   N   A GAI   + + ++ +F  YF  L     +   N W  E W+  + C                                            ++  P   S  SR +     +     + F  + K+Q V DAVYA+A+ L   +  +C    +E           +   A+ NIDG  FY++ L+  +FTD  G    F   GD    Y I  Y          + + ++    Y  IG +  + L +  +  W  +    P S+CS  C +G  +   K+ +CCW CS C+  EY++N T C  C +G WP ++R GC+ L++  +K   W    +++P IL+  G   T  V+ V+  Y  TP+V+ASGRELS+++L   ++CY ++FV L KP+   CAI+R  +G  F+ +Y+++  KTNRI RIF +  ++A+RP  ISP SQ+++ A+L  VQL+ + IWL   PPG R+     +  VL C +    FL SL Y+  LI +CT YA+KTRK+PENFNE+KFIGF+MYTTCV+WL++I  +FGT   F++Q S+L IS+S+SA V L C+F PKL II  +  KNVRK    +M + + R   N S    AN  +  ++YT L
Sbjct:   51 GDILIGGVFPVHSKSLNGDEPCGEIAETRGVHRVEAMLYALDQINSQNDFLRGYKLGALILDSCSNPAYALNQSLDFVRDMIG-SSEASDYVCLDGSDPNLKKQSQKKNVAAVVGGSYSSVSVQLANLLRLFRIAQVSPASTNADLSDKNRFEYFARTVPSDDYQAMAMVEIAVKFKWSYVSLVYSADEYGELGADAFKKEARKKGICIALEERIQNKKESFTESINNLVQKLQPEKNVGATVVVLFVGTEYIPDILRYTAERMKLTSGAKKRIIWLASESWDRNNDKYTAGDNRLAAQGAIVLMLASQKVPSFEEYFMSLHPGTEAFERNKWLRELWQVKYKC--------------------------------------------EFDTP-PGSTASRCE-----DIKQSTEGFNADDKVQFVIDAVYAIAHGLQSMKQAICPDDAIENHWISRYSKQPEICHAMQNIDGSDFYQNYLLKVNFTDIVGKRFRFSPQGDGPASYTILTYKPKSMDKKRRMTDDESSPSDYVEIGHWSENNLTIYEKNLW-WDPDHTPVSVCSLPCKIGFRKQLIKDEQCCWACSKCEDYEYLINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFST--RSAQRPRFISPISQVVMTAMLAGVQLIGSLIWLSVVPPGWRHHYPTRDQVVLTCNVPDHHFLYSLAYDGFLIVLCTTYAVKTRKVPENFNETKFIGFSMYTTCVVWLSWIFFFFGTGSDFQIQTSSLCISISMSANVALACIFSPKLWIILFEKHKNVRKQEGESMLNKSSRSLGNCSSRLCANSIDEPNQYTAL 922          
BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0
Identity = 340/926 (36.72%), Postives = 502/926 (54.21%), Query Frame = 2
Query:  185 GDIILGGLFPVHDSE---TELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEV-LRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFS-KTRVVVLFTRLDHTKLLL----NAVKIMNYSN-YFLWIASDGWGQENGPVTNNSN--VANGAITFEVKTVEIKNFTTYFHQLTYNRNS--NNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-----------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNY----------IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGW---LAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL---TMSSTTYRKPTNSSGSF-ANHREMNSEYTPL 2827
            GDI++GG+FPVH       E C +I   RG+ R+EAML+ + +IN++ D L    +GA ILD+CS   YAL QSLDF++  +  +++ASDY C D S+  L+     + +  VVGGSYSSVS+ +ANLLRLF I Q+S AST+A LS+K     FART+PSD  QA AM E+   F W+YVS V S+ +YG+ G DAF KE++K G+CIA +E I  K       +  +V+ L  E +    VVVLF   ++   +L      +K+ + +    +W+AS+ W + N   T   N   A GAI   + + ++ +F  YF  L     +   N W  E W+  + C                                            ++  P   S  SR +     +     + F  + K+Q V DAVYA+A+ L   +  +C    +E           +   A+ NIDG  FY++ L+  +FTD  G    F   GD    Y I  Y          + + ++    Y  IG +  + L +  +  W  +    P S+CS  C +G  +   K+ +CCW CS C+  EY++N T C  C +G WP ++R GC+ L++  +K   W    +++P IL+  G   T  V+ V+  Y  TP+V+ASGRELS+++L   ++CY ++FV L KP+   CAI+R  +G  F+ +Y+++  KTNRI RIF +  ++A+RP  ISP SQ+++ A+L  VQL+ + IWL   PPG R+     +  VL C +    FL SL Y+  LI +CT YA+KTRK+PENFNE+KFIGF+MYTTCV+WL++I  +FGT   F++Q S+L IS+S+SA V L C+F PKL II  +  KNVRK    +M + + R   N S    AN  +  ++YT L
Sbjct:   40 GDILIGGVFPVHSKSLNGDEPCGEIAETRGVHRVEAMLYALDQINSQNDFLRGYKLGALILDSCSNPAYALNQSLDFVRDMIG-SSEASDYVCLDGSDPNLKKQSQKKNVAAVVGGSYSSVSVQLANLLRLFRIAQVSPASTNADLSDKNRFEYFARTVPSDDYQAMAMVEIAVKFKWSYVSLVYSADEYGELGADAFKKEARKKGICIALEERIQNKKESFTESINNLVQKLQPEKNVGATVVVLFVGTEYIPDILRYTAERMKLTSGAKKRIIWLASESWDRNNDKYTAGDNRLAAQGAIVLMLASQKVPSFEEYFMSLHPGTEAFERNKWLRELWQVKYKC--------------------------------------------EFDTP-PGSTASRCE-----DIKQSTEGFNADDKVQFVIDAVYAIAHGLQSMKQAICPDDAIENHWISRYSKQPEICHAMQNIDGSDFYQNYLLKVNFTDIVGKRFRFSPQGDGPASYTILTYKPKSMDKKRRMTDDESSPSDYVEIGHWSENNLTIYEKNLW-WDPDHTPVSVCSLPCKIGFRKQLIKDEQCCWACSKCEDYEYLINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFST--RSAQRPRFISPISQVVMTAMLAGVQLIGSLIWLSVVPPGWRHHYPTRDQVVLTCNVPDHHFLYSLAYDGFLIVLCTTYAVKTRKVPENFNETKFIGFSMYTTCVVWLSWIFFFFGTGSDFQIQTSSLCISISMSANVALACIFSPKLWIILFEKHKNVRKQEGESMLNKSSRSLGNCSSRLCANSIDEPNQYTAL 911          
BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 340/926 (36.72%), Postives = 501/926 (54.10%), Query Frame = 2
Query:  185 GDIILGGLFPVHDSE---TELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEV-LRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFS-KTRVVVLFTRLDHTKLLL----NAVKIMNYSN-YFLWIASDGWGQENGPVTNNSN--VANGAITFEVKTVEIKNFTTYFHQLTYNRNS--NNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-----------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNY----------IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGW---LAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL---TMSSTTYRKPTNSSGSF-ANHREMNSEYTPL 2827
            GDI++GG+FPVH       E C +I   RG+ R+EAML+ + +IN++ D L    +GA ILD+CS   YAL QSLDF++  +  +++ASDY C D S+  L+     + +  VVGGSYSSVS+ +ANLLRLF I Q+S AST+A LS+K     FART+PSD  QA AM E+   F W+YVS V S+ +YG+ G DAF KE++K G+CIA +E I  K       +  +V+ L  E +    VVVLF   ++   +L      +K+ + +    +W+AS+ W + N   T   N   A GAI   + + ++ +F  YF  L     +   N W  E W                                            Q  +  ++  P   S  SR +     +     + F  + K+Q V DAVYA+A+ L   +  +C    +E           +   A+ NIDG  FY++ L+  +FTD  G    F   GD    Y I  Y          + + ++    Y  IG +  + L +  +  W  +    P S+CS  C +G  +   K+ +CCW CS C+  EY++N T C  C +G WP ++R GC+ L++  +K   W    +++P IL+  G   T  V+ V+  Y  TP+V+ASGRELS+++L   ++CY ++FV L KP+   CAI+R  +G  F+ +Y+++  KTNRI RIF +  ++A+RP  ISP SQ+++ A+L  VQL+ + IWL   PPG R+     +  VL C +    FL SL Y+  LI +CT YA+KTRK+PENFNE+KFIGF+MYTTCV+WL++I  +FGT   F++Q S+L IS+S+SA V L C+F PKL II  +  KNVRK    +M + + R   N S    AN  +  ++YT L
Sbjct:   54 GDILIGGVFPVHSKSLNGDEPCGEIAETRGVHRVEAMLYALDQINSQNDFLRGYKLGALILDSCSNPAYALNQSLDFVRDMIG-SSEASDYVCLDGSDPNLKKQSQKKNVAAVVGGSYSSVSVQLANLLRLFRIAQVSPASTNADLSDKNRFEYFARTVPSDDYQAMAMVEIAVKFKWSYVSLVYSADEYGELGADAFKKEARKKGICIALEERIQNKKESFTESINNLVQKLQPEKNVGATVVVLFVGTEYIPDILRYTAERMKLTSGAKKRIIWLASESWDRNNDKYTAGDNRLAAQGAIVLMLASQKVPSFEEYFMSLHPGTEAFERNKWLRELW--------------------------------------------QVKYKCEFDTP-PGSTASRCE-----DIKQSTEGFNADDKVQFVIDAVYAIAHGLQSMKQAICPDDAIENHWISRYSKQPEICHAMQNIDGSDFYQNYLLKVNFTDIVGKRFRFSPQGDGPASYTILTYKPKSMDKKRRMTDDESSPSDYVEIGHWSENNLTIYEKNLW-WDPDHTPVSVCSLPCKIGFRKQLIKDEQCCWACSKCEDYEYLINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFST--RSAQRPRFISPISQVVMTAMLAGVQLIGSLIWLSVVPPGWRHHYPTRDQVVLTCNVPDHHFLYSLAYDGFLIVLCTTYAVKTRKVPENFNETKFIGFSMYTTCVVWLSWIFFFFGTGSDFQIQTSSLCISISMSANVALACIFSPKLWIILFEKHKNVRKQEGESMLNKSSRSLGNCSSRLCANSIDEPNQYTAL 925          
BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 531.946 bits (1369), Expect = 2.992e-173
Identity = 323/890 (36.29%), Postives = 478/890 (53.71%), Query Frame = 2
Query:  284 MLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEV-LRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFS-KTRVVVLFTRLDHTKLLL----NAVKIMNYSN-YFLWIASDGWGQENGPVTNNSN--VANGAITFEVKTVEIKNFTTYFHQLTYNRNS--NNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-----------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNY----------IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGW---LAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL---TMSSTTYRKPTNSSGSF-ANHREMNSEYTPL 2827
            ML+ + +IN++ D L    +GA ILD+CS   YAL QSLDF++  +  +++ASDY C D S+  L+     + +  VVGGSYSSVS+ +ANLLRLF I Q+S AST+A LS+K     FART+PSD  QA AM E+   F W+YVS V S+ +YG+ G DAF KE++K G+CIA +E I  K       +  +V+ L  E +    VVVLF   ++   +L      +K+ + +    +W+AS+ W + N   T   N   A GAI   + + ++ +F  YF  L     +   N W  E W                                            Q  +  ++  P   S  SR +     +     + F  + K+Q V DAVYA+A+ L   +  +C    +E           +   A+ NIDG  FY++ L+  +FTD  G    F   GD    Y I  Y          + + ++    Y  IG +  + L +  +  W  +    P S+CS  C +G  +   K+ +CCW CS C+  EY++N T C  C +G WP ++R GC+ L++  +K   W    +++P IL+  G   T  V+ V+  Y  TP+V+ASGRELS+++L   ++CY ++FV L KP+   CAI+R  +G  F+ +Y+++  KTNRI RIF +  ++A+RP  ISP SQ+++ A+L  VQL+ + IWL   PPG R+     +  VL C +    FL SL Y+  LI +CT YA+KTRK+PENFNE+KFIGF+MYTTCV+WL++I  +FGT   F++Q S+L IS+S+SA V L C+F PKL II  +  KNVRK    +M + + R   N S    AN  +  ++YT L
Sbjct:    1 MLYALDQINSQNDFLRGYKLGALILDSCSNPAYALNQSLDFVRDMIG-SSEASDYVCLDGSDPNLKKQSQKKNVAAVVGGSYSSVSVQLANLLRLFRIAQVSPASTNADLSDKNRFEYFARTVPSDDYQAMAMVEIAVKFKWSYVSLVYSADEYGELGADAFKKEARKKGICIALEERIQNKKESFTESINNLVQKLQPEKNVGATVVVLFVGTEYIPDILRYTAERMKLTSGAKKRIIWLASESWDRNNDKYTAGDNRLAAQGAIVLMLASQKVPSFEEYFMSLHPGTEAFERNKWLRELW--------------------------------------------QVKYKCEFDTP-PGSTASRCE-----DIKQSTEGFNADDKVQFVIDAVYAIAHGLQSMKQAICPDDAIENHWISRYSKQPEICHAMQNIDGSDFYQNYLLKVNFTDIVGKRFRFSPQGDGPASYTILTYKPKSMDKKRRMTDDESSPSDYVEIGHWSENNLTIYEKNLW-WDPDHTPVSVCSLPCKIGFRKQLIKDEQCCWACSKCEDYEYLINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFST--RSAQRPRFISPISQVVMTAMLAGVQLIGSLIWLSVVPPGWRHHYPTRDQVVLTCNVPDHHFLYSLAYDGFLIVLCTTYAVKTRKVPENFNETKFIGFSMYTTCVVWLSWIFFFFGTGSDFQIQTSSLCISISMSANVALACIFSPKLWIILFEKHKNVRKQEGESMLNKSSRSLGNCSSRLCANSIDEPNQYTAL 836          
BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Match: mgl-1 (Probable metabotropic glutamate receptor mgl-1 [Source:UniProtKB/Swiss-Prot;Acc:Q09630])

HSP 1 Score: 531.946 bits (1369), Expect = 2.992e-173
Identity = 323/890 (36.29%), Postives = 478/890 (53.71%), Query Frame = 2
Query:  284 MLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEV-LRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFS-KTRVVVLFTRLDHTKLLL----NAVKIMNYSN-YFLWIASDGWGQENGPVTNNSN--VANGAITFEVKTVEIKNFTTYFHQLTYNRNS--NNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-----------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNY----------IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGW---LAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL---TMSSTTYRKPTNSSGSF-ANHREMNSEYTPL 2827
            ML+ + +IN++ D L    +GA ILD+CS   YAL QSLDF++  +  +++ASDY C D S+  L+     + +  VVGGSYSSVS+ +ANLLRLF I Q+S AST+A LS+K     FART+PSD  QA AM E+   F W+YVS V S+ +YG+ G DAF KE++K G+CIA +E I  K       +  +V+ L  E +    VVVLF   ++   +L      +K+ + +    +W+AS+ W + N   T   N   A GAI   + + ++ +F  YF  L     +   N W  E W                                            Q  +  ++  P   S  SR +     +     + F  + K+Q V DAVYA+A+ L   +  +C    +E           +   A+ NIDG  FY++ L+  +FTD  G    F   GD    Y I  Y          + + ++    Y  IG +  + L +  +  W  +    P S+CS  C +G  +   K+ +CCW CS C+  EY++N T C  C +G WP ++R GC+ L++  +K   W    +++P IL+  G   T  V+ V+  Y  TP+V+ASGRELS+++L   ++CY ++FV L KP+   CAI+R  +G  F+ +Y+++  KTNRI RIF +  ++A+RP  ISP SQ+++ A+L  VQL+ + IWL   PPG R+     +  VL C +    FL SL Y+  LI +CT YA+KTRK+PENFNE+KFIGF+MYTTCV+WL++I  +FGT   F++Q S+L IS+S+SA V L C+F PKL II  +  KNVRK    +M + + R   N S    AN  +  ++YT L
Sbjct:    1 MLYALDQINSQNDFLRGYKLGALILDSCSNPAYALNQSLDFVRDMIG-SSEASDYVCLDGSDPNLKKQSQKKNVAAVVGGSYSSVSVQLANLLRLFRIAQVSPASTNADLSDKNRFEYFARTVPSDDYQAMAMVEIAVKFKWSYVSLVYSADEYGELGADAFKKEARKKGICIALEERIQNKKESFTESINNLVQKLQPEKNVGATVVVLFVGTEYIPDILRYTAERMKLTSGAKKRIIWLASESWDRNNDKYTAGDNRLAAQGAIVLMLASQKVPSFEEYFMSLHPGTEAFERNKWLRELW--------------------------------------------QVKYKCEFDTP-PGSTASRCE-----DIKQSTEGFNADDKVQFVIDAVYAIAHGLQSMKQAICPDDAIENHWISRYSKQPEICHAMQNIDGSDFYQNYLLKVNFTDIVGKRFRFSPQGDGPASYTILTYKPKSMDKKRRMTDDESSPSDYVEIGHWSENNLTIYEKNLW-WDPDHTPVSVCSLPCKIGFRKQLIKDEQCCWACSKCEDYEYLINETHCVGCEQGWWPTKDRKGCFDLSLSQLKYMRWRSMYSLVPTILAVFGIIATLFVIVVYVIYNETPVVKASGRELSYILLISMIMCYCMTFVLLSKPSAIVCAIKRTGIGFAFSCLYSAMFVKTNRIFRIFST--RSAQRPRFISPISQVVMTAMLAGVQLIGSLIWLSVVPPGWRHHYPTRDQVVLTCNVPDHHFLYSLAYDGFLIVLCTTYAVKTRKVPENFNETKFIGFSMYTTCVVWLSWIFFFFGTGSDFQIQTSSLCISISMSANVALACIFSPKLWIILFEKHKNVRKQEGESMLNKSSRSLGNCSSRLCANSIDEPNQYTAL 836          
BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Match: mGluR (gene:FBgn0019985 transcript:FBtr0089184)

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 421/939 (44.83%), Postives = 569/939 (60.60%), Query Frame = 2
Query:  185 GDIILGGLFPVHD-SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSE-VLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC-----------KPFVLE-------------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY---DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMNSEYTPLPPPFNSQSHHLVVVSIQSHS--PSINEP 2905
            GDIILGGLFPVH+  E   C     +RG+QRLEAML+ I  +NN P+ILP I IG  ILDTCS+DTYAL QSL F+++SL +N D S Y C D S   LR   ++  +  V+GGSYSSVS+ VANLLRLF IPQ+S AST+  LS+K    +FART+P D  Q+ A+ +++ +FNW+YVST+ S G YG+ GI+A  KE+ +  VCIA  E + P+     +   + +  Q+    R VVLFTR +  + +L A K  N S  F WIASDGWG++   +    ++A GAIT E+++  I +F  Y  QLT   N  NPWF EYWE+ F+C+       ++  SVK   S          N TD NK                 VK++ +    +  S K+  ++QESK Q V DAVYA AY L    +  C           K    E             +    + N DG  FY + L+N SF D  G+ V FD  GD + +Y+I NY R + +  Y YK IG++  +GL LNSE     +E E P S CS  C VG I+    ++ CCW C  C+S EYV +   C+ C  G WPY ++  CY L + YMK +   A+IPM ++  G A T+ V+ +F    +TP+VRASGRELS+ +L G LVCY  +F  + KPT  SC +QR  +G+GF+++Y++LLTKTNRI+RIF SA K+A+R   ISP+SQ++I   LI++Q+L   IW+   PPG R+   DR++    +LKCKI+  +FL S +YNM+LI++CT YAIKTRKIPENFNESKFIGFTMYTTC+IWLAF+ IYFGT +S+EVQ +TL IS+SLSA V L+CL+ PK++I+   P+KNVRKLTM+ST YR+   S+ + A     +S Y+    P  S      V +  S S  P+ N P
Sbjct:   43 GDIILGGLFPVHEKGEGAPCGPKVYNRGVQRLEAMLYAIDRVNNDPNILPGITIGVHILDTCSRDTYALNQSLQFVRASL-NNLDTSGYECADGSSPQLRKNASSGPVFGVIGGSYSSVSLQVANLLRLFHIPQVSPASTAKTLSDKTRFDLFARTVPPDTFQSVALVDILKNFNWSYVSTIHSEGSYGEYGIEALHKEATERNVCIAVAEKV-PSAADDKVFDSIISKLQKKPNARGVVLFTRAEDARRILQAAKRANLSQPFHWIASDGWGKQQKLLEGLEDIAEGAITVELQSEIIADFDRYMMQLTPETNQRNPWFAEYWEDTFNCV-------LTSLSVKPDTSNS-------ANSTD-NKIG---------------VKAKTECDDSYRLSEKV-GYEQESKTQFVVDAVYAFAYALHNLHNDRCNTQSDQTTETRKHLQSESVWYRKISTDTKSQACPDMANYDGKEFYNNYLLNVSFIDLAGSEVKFDRQGDGLARYDILNYQRQENSSGYQYKVIGKW-FNGLQLNSETVVWNKETEQPTSACSLPCEVGMIKKQQGDT-CCWICDSCESFEYVYDEFTCKDCGPGLWPYADKLSCYALDIQYMKWNSLFALIPMAIAIFGIALTSIVIVLFAKNHDTPLVRASGRELSYTLLFGILVCYCNTFALIAKPTIGSCVLQRFGIGVGFSIIYSALLTKTNRISRIFHSASKSAQRLKYISPQSQVVITTSLIAIQVLITMIWMVVEPPGTRFYYPDRRE---VILKCKIQDMSFLFSQLYNMILITICTIYAIKTRKIPENFNESKFIGFTMYTTCIIWLAFVPIYFGTGNSYEVQTTTLCISISLSASVALVCLYSPKVYILVFHPDKNVRKLTMNSTVYRR---SAAAVAQGAPTSSGYSRTHAPGTSALTGGAVGTNASSSTLPTQNSP 940          
BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Match: mGluR (gene:FBgn0019985 transcript:FBtr0332858)

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 421/939 (44.83%), Postives = 569/939 (60.60%), Query Frame = 2
Query:  185 GDIILGGLFPVHD-SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSE-VLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC-----------KPFVLE-------------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY---DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMNSEYTPLPPPFNSQSHHLVVVSIQSHS--PSINEP 2905
            GDIILGGLFPVH+  E   C     +RG+QRLEAML+ I  +NN P+ILP I IG  ILDTCS+DTYAL QSL F+++SL +N D S Y C D S   LR   ++  +  V+GGSYSSVS+ VANLLRLF IPQ+S AST+  LS+K    +FART+P D  Q+ A+ +++ +FNW+YVST+ S G YG+ GI+A  KE+ +  VCIA  E + P+     +   + +  Q+    R VVLFTR +  + +L A K  N S  F WIASDGWG++   +    ++A GAIT E+++  I +F  Y  QLT   N  NPWF EYWE+ F+C+       ++  SVK   S          N TD NK                 VK++ +    +  S K+  ++QESK Q V DAVYA AY L    +  C           K    E             +    + N DG  FY + L+N SF D  G+ V FD  GD + +Y+I NY R + +  Y YK IG++  +GL LNSE     +E E P S CS  C VG I+    ++ CCW C  C+S EYV +   C+ C  G WPY ++  CY L + YMK +   A+IPM ++  G A T+ V+ +F    +TP+VRASGRELS+ +L G LVCY  +F  + KPT  SC +QR  +G+GF+++Y++LLTKTNRI+RIF SA K+A+R   ISP+SQ++I   LI++Q+L   IW+   PPG R+   DR++    +LKCKI+  +FL S +YNM+LI++CT YAIKTRKIPENFNESKFIGFTMYTTC+IWLAF+ IYFGT +S+EVQ +TL IS+SLSA V L+CL+ PK++I+   P+KNVRKLTM+ST YR+   S+ + A     +S Y+    P  S      V +  S S  P+ N P
Sbjct:   43 GDIILGGLFPVHEKGEGAPCGPKVYNRGVQRLEAMLYAIDRVNNDPNILPGITIGVHILDTCSRDTYALNQSLQFVRASL-NNLDTSGYECADGSSPQLRKNASSGPVFGVIGGSYSSVSLQVANLLRLFHIPQVSPASTAKTLSDKTRFDLFARTVPPDTFQSVALVDILKNFNWSYVSTIHSEGSYGEYGIEALHKEATERNVCIAVAEKV-PSAADDKVFDSIISKLQKKPNARGVVLFTRAEDARRILQAAKRANLSQPFHWIASDGWGKQQKLLEGLEDIAEGAITVELQSEIIADFDRYMMQLTPETNQRNPWFAEYWEDTFNCV-------LTSLSVKPDTSNS-------ANSTD-NKIG---------------VKAKTECDDSYRLSEKV-GYEQESKTQFVVDAVYAFAYALHNLHNDRCNTQSDQTTETRKHLQSESVWYRKISTDTKSQACPDMANYDGKEFYNNYLLNVSFIDLAGSEVKFDRQGDGLARYDILNYQRQENSSGYQYKVIGKW-FNGLQLNSETVVWNKETEQPTSACSLPCEVGMIKKQQGDT-CCWICDSCESFEYVYDEFTCKDCGPGLWPYADKLSCYALDIQYMKWNSLFALIPMAIAIFGIALTSIVIVLFAKNHDTPLVRASGRELSYTLLFGILVCYCNTFALIAKPTIGSCVLQRFGIGVGFSIIYSALLTKTNRISRIFHSASKSAQRLKYISPQSQVVITTSLIAIQVLITMIWMVVEPPGTRFYYPDRRE---VILKCKIQDMSFLFSQLYNMILITICTIYAIKTRKIPENFNESKFIGFTMYTTCIIWLAFVPIYFGTGNSYEVQTTTLCISISLSASVALVCLYSPKVYILVFHPDKNVRKLTMNSTVYRR---SAAAVAQGAPTSSGYSRTHAPGTSALTGGAVGTNASSSTLPTQNSP 940          
BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Match: mtt (gene:FBgn0050361 transcript:FBtr0330608)

HSP 1 Score: 591.267 bits (1523), Expect = 0.000e+0
Identity = 343/873 (39.29%), Postives = 482/873 (55.21%), Query Frame = 2
Query:  167 QSAIYNGDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKE-MIKPNPLHSDLL--AIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSR---KQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCK--PFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNE--YVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCK--IETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTM 2743
            + AI  GD+ILGGL  VH  E  + C  I P  GIQ LEAMLFTI  IN R  +LPNI +GA ILD C KD+Y L+ ++DFIK S+S+ +DA +Y+C         T+  + I  VVG + S  SI VANLLRLF IPQ+SY STS  LS K+    F+RT+PSD  Q KAM E+V    W+YVS +    +YG    +   +   +  +CIA KE ++K + +  D+    IV+ L  +  + R  ++F      + ++ AV+  N +  F WI SDGW   N    +      G ++ + +   ++ F  YF  LT   N  NPWF E+WE+ F C                                              R+P S S       KQ  T    S +  +F  E ++Q V DAV A AY L      LC   P + E    A+    G    K L    F    G+   FD NGD   +YNI ++ +  + G+Y++  +GE+    L LN +EV +     + P S+CS  C VGQ + Y +   CCW C  C + +  +  + T C++C  G  P  ++  C  +   Y++     AI  M  S  G   T  VMGVF  + +TPIVRASGRELS+++L+G  +CY V+F  +LKPT   CAIQR  +G  F V+YA+LLTKTNRIARIF++ +++AKRP  ISPKSQL+ICA L+SVQ+L N +W+  +P    +     E  +L C   I+  +++++  Y + LI +CT YA+ TRKIPE FNESK IGFTMYTTCVIWLAF+ +YFGT +   ++I+++ +++SLSA VT+ CLF PKL+II ++PE+NVR+  M
Sbjct:  387 REAIVEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLFTIDRIN-REQLLPNITLGAHILDDCDKDSYGLEMAVDFIKGSISNIDDA-EYHCNK-------TQVRKVISGVVGAASSVTSIQVANLLRLFRIPQVSYFSTSPELSNKQRFEYFSRTIPSDHYQVKAMVEIVKRMGWSYVSIIYEESNYGIKAFEELEELLARHNICIAIKEKLVKDSGVAEDIAYDNIVQKLLTK-PRARGAIIFGSDQEVRQVMRAVRRANATGSFSWIGSDGWSARNLVSDDYEPEVEGTLSVQPQANPVRGFEEYFLSLTVENNQRNPWFVEFWEDHFQC----------------------------------------------RYPGSTSTPYNNYTKQCTTKERLSRQNTDF--EDQLQFVSDAVMAFAYALRDMHRDLCGGGPSLCE----AMKPTKGADLLKYLRKVEFEGLSGDEFRFDGNGDGPARYNIIHF-KQSQAGQYHWVKVGEYTEGELRLNMTEVKFKRLSPKPPESVCSLPCLVGQAKKYVEGESCCWHCFNCTTYQIRHPDDETHCKLCKLGTLPDAHKQYCRPIPEIYLRPESAWAIGAMAFSATGILVTLFVMGVFVRHNDTPIVRASGRELSYILLAGIFMCYGVTFALVLKPTNIVCAIQRFGVGFCFTVVYAALLTKTNRIARIFKAGKQSAKRPSFISPKSQLVICACLVSVQILINGVWMVIAPSHAMHHYPTREDNLLVCDSYIDA-SYMIAFSYPIFLIVICTVYAVLTRKIPEAFNESKHIGFTMYTTCVIWLAFVPLYFGTANHVPLRITSMSVTISLSASVTIACLFSPKLYIILIRPERNVRQSMM 1195          

HSP 2 Score: 93.2041 bits (230), Expect = 9.156e-19
Identity = 52/126 (41.27%), Postives = 75/126 (59.52%), Query Frame = 2
Query:  167 QSAIYNGDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSI 541
             +A+  GD+ILGGL  VH  E  + C  I P  GIQ LEAML+T+ ++N +  +LPN+ +GA +LD C KDTY L+ ++DFIK+ +  N   S+Y       +   T+A  K++T    S  SV I
Sbjct:   67 HAAVLEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLYTLDQVNKQ-QLLPNVTLGAHLLDDCDKDTYGLEMAVDFIKAHIQIN---SEY-------ITVKTEAKAKMKTFCDESKWSVQI 181          
BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Match: mtt (gene:FBgn0050361 transcript:FBtr0273325)

HSP 1 Score: 590.497 bits (1521), Expect = 0.000e+0
Identity = 343/873 (39.29%), Postives = 482/873 (55.21%), Query Frame = 2
Query:  167 QSAIYNGDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKE-MIKPNPLHSDLL--AIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSR---KQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCK--PFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNE--YVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCK--IETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTM 2743
            + AI  GD+ILGGL  VH  E  + C  I P  GIQ LEAMLFTI  IN R  +LPNI +GA ILD C KD+Y L+ ++DFIK S+S+ +DA +Y+C         T+  + I  VVG + S  SI VANLLRLF IPQ+SY STS  LS K+    F+RT+PSD  Q KAM E+V    W+YVS +    +YG    +   +   +  +CIA KE ++K + +  D+    IV+ L  +  + R  ++F      + ++ AV+  N +  F WI SDGW   N    +      G ++ + +   ++ F  YF  LT   N  NPWF E+WE+ F C                                              R+P S S       KQ  T    S +  +F  E ++Q V DAV A AY L      LC   P + E    A+    G    K L    F    G+   FD NGD   +YNI ++ +  + G+Y++  +GE+    L LN +EV +     + P S+CS  C VGQ + Y +   CCW C  C + +  +  + T C++C  G  P  ++  C  +   Y++     AI  M  S  G   T  VMGVF  + +TPIVRASGRELS+++L+G  +CY V+F  +LKPT   CAIQR  +G  F V+YA+LLTKTNRIARIF++ +++AKRP  ISPKSQL+ICA L+SVQ+L N +W+  +P    +     E  +L C   I+  +++++  Y + LI +CT YA+ TRKIPE FNESK IGFTMYTTCVIWLAF+ +YFGT +   ++I+++ +++SLSA VT+ CLF PKL+II ++PE+NVR+  M
Sbjct:  387 REAIVEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLFTIDRIN-REQLLPNITLGAHILDDCDKDSYGLEMAVDFIKGSISNIDDA-EYHCNK-------TQVRKVISGVVGAASSVTSIQVANLLRLFRIPQVSYFSTSPELSNKQRFEYFSRTIPSDHYQVKAMVEIVKRMGWSYVSIIYEESNYGIKAFEELEELLARHNICIAIKEKLVKDSGVAEDIAYDNIVQKLLTK-PRARGAIIFGSDQEVRQVMRAVRRANATGSFSWIGSDGWSARNLVSDDYEPEVEGTLSVQPQANPVRGFEEYFLSLTVENNQRNPWFVEFWEDHFQC----------------------------------------------RYPGSTSTPYNNYTKQCTTKERLSRQNTDF--EDQLQFVSDAVMAFAYALRDMHRDLCGGGPSLCE----AMKPTKGADLLKYLRKVEFEGLSGDEFRFDGNGDGPARYNIIHF-KQSQAGQYHWVKVGEYTEGELRLNMTEVKFKRLSPKPPESVCSLPCLVGQAKKYVEGESCCWHCFNCTTYQIRHPDDETHCKLCKLGTLPDAHKQYCRPIPEIYLRPESAWAIGAMAFSATGILVTLFVMGVFVRHNDTPIVRASGRELSYILLAGIFMCYGVTFALVLKPTNIVCAIQRFGVGFCFTVVYAALLTKTNRIARIFKAGKQSAKRPSFISPKSQLVICACLVSVQILINGVWMVIAPSHAMHHYPTREDNLLVCDSYIDA-SYMIAFSYPIFLIVICTVYAVLTRKIPEAFNESKHIGFTMYTTCVIWLAFVPLYFGTANHVPLRITSMSVTISLSASVTIACLFSPKLYIILIRPERNVRQSMM 1195          

HSP 2 Score: 93.2041 bits (230), Expect = 9.331e-19
Identity = 52/126 (41.27%), Postives = 75/126 (59.52%), Query Frame = 2
Query:  167 QSAIYNGDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSI 541
             +A+  GD+ILGGL  VH  E  + C  I P  GIQ LEAML+T+ ++N +  +LPN+ +GA +LD C KDTY L+ ++DFIK+ +  N   S+Y       +   T+A  K++T    S  SV I
Sbjct:   67 HAAVLEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLYTLDQVNKQ-QLLPNVTLGAHLLDDCDKDTYGLEMAVDFIKAHIQIN---SEY-------ITVKTEAKAKMKTFCDESKWSVQI 181          
BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Match: mtt (gene:FBgn0050361 transcript:FBtr0273327)

HSP 1 Score: 590.112 bits (1520), Expect = 0.000e+0
Identity = 343/873 (39.29%), Postives = 482/873 (55.21%), Query Frame = 2
Query:  167 QSAIYNGDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKE-MIKPNPLHSDLL--AIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSR---KQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCK--PFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNE--YVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCK--IETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTM 2743
            + AI  GD+ILGGL  VH  E  + C  I P  GIQ LEAMLFTI  IN R  +LPNI +GA ILD C KD+Y L+ ++DFIK S+S+ +DA +Y+C         T+  + I  VVG + S  SI VANLLRLF IPQ+SY STS  LS K+    F+RT+PSD  Q KAM E+V    W+YVS +    +YG    +   +   +  +CIA KE ++K + +  D+    IV+ L  +  + R  ++F      + ++ AV+  N +  F WI SDGW   N    +      G ++ + +   ++ F  YF  LT   N  NPWF E+WE+ F C                                              R+P S S       KQ  T    S +  +F  E ++Q V DAV A AY L      LC   P + E    A+    G    K L    F    G+   FD NGD   +YNI ++ +  + G+Y++  +GE+    L LN +EV +     + P S+CS  C VGQ + Y +   CCW C  C + +  +  + T C++C  G  P  ++  C  +   Y++     AI  M  S  G   T  VMGVF  + +TPIVRASGRELS+++L+G  +CY V+F  +LKPT   CAIQR  +G  F V+YA+LLTKTNRIARIF++ +++AKRP  ISPKSQL+ICA L+SVQ+L N +W+  +P    +     E  +L C   I+  +++++  Y + LI +CT YA+ TRKIPE FNESK IGFTMYTTCVIWLAF+ +YFGT +   ++I+++ +++SLSA VT+ CLF PKL+II ++PE+NVR+  M
Sbjct:  220 REAIVEGDVILGGLMMVHSREDSITCGPIMPQGGIQALEAMLFTIDRIN-REQLLPNITLGAHILDDCDKDSYGLEMAVDFIKGSISNIDDA-EYHCNK-------TQVRKVISGVVGAASSVTSIQVANLLRLFRIPQVSYFSTSPELSNKQRFEYFSRTIPSDHYQVKAMVEIVKRMGWSYVSIIYEESNYGIKAFEELEELLARHNICIAIKEKLVKDSGVAEDIAYDNIVQKLLTK-PRARGAIIFGSDQEVRQVMRAVRRANATGSFSWIGSDGWSARNLVSDDYEPEVEGTLSVQPQANPVRGFEEYFLSLTVENNQRNPWFVEFWEDHFQC----------------------------------------------RYPGSTSTPYNNYTKQCTTKERLSRQNTDF--EDQLQFVSDAVMAFAYALRDMHRDLCGGGPSLCE----AMKPTKGADLLKYLRKVEFEGLSGDEFRFDGNGDGPARYNIIHF-KQSQAGQYHWVKVGEYTEGELRLNMTEVKFKRLSPKPPESVCSLPCLVGQAKKYVEGESCCWHCFNCTTYQIRHPDDETHCKLCKLGTLPDAHKQYCRPIPEIYLRPESAWAIGAMAFSATGILVTLFVMGVFVRHNDTPIVRASGRELSYILLAGIFMCYGVTFALVLKPTNIVCAIQRFGVGFCFTVVYAALLTKTNRIARIFKAGKQSAKRPSFISPKSQLVICACLVSVQILINGVWMVIAPSHAMHHYPTREDNLLVCDSYIDA-SYMIAFSYPIFLIVICTVYAVLTRKIPEAFNESKHIGFTMYTTCVIWLAFVPLYFGTANHVPLRITSMSVTISLSASVTIACLFSPKLYIILIRPERNVRQSMM 1028          
BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Match: grm2a (glutamate receptor, metabotropic 2a [Source:ZFIN;Acc:ZDB-GENE-030131-8097])

HSP 1 Score: 688.723 bits (1776), Expect = 0.000e+0
Identity = 385/895 (43.02%), Postives = 530/895 (59.22%), Query Frame = 2
Query:  155 DNKYQSAIYNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMN 2809
            D   +  + +GD+++GGLFPVH      + C +IN  RGIQRLEAML  + +IN    ILP + +GA ILDTCSKDTYAL+QSL+F+++SL+  +D S+Y C D S  + H      I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++ L +CIA    +  +        ++++L Q+ S  +VV+LFTR +  + LL A K MN S  F+W+ASDGWG +   V  + +VA+GA T E+ +  I  F  YF  L    N+ NPWF E+WE  F C            S+  +  GK S                    RD +F                         +QESKI  V +AVYA+A  L   +  LC      K   A+  ++G   YKD I  +  D+        N++ FD+ GDS+G+YNI++Y  +K+  +Y Y+ +G +  D L LN+ +  P E + +P S CS+ C   +I+       CCW C  C+  +Y+++   C  C+ G+WP  N TGCY L   Y+      AI P+ ++ LG   T  V+G+F     TP+V+ASGRELS+++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ ICA LIS QLL   +WL    PG+R +   ++ +   LKC  +  + L+SL YN +LI +CT+YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L +++T +   T    SF+     N
Sbjct:   48 DTSKKEIVMDGDLVIGGLFPVHHKGEGAQDCGRINTQRGIQRLEAMLLALDKINQDDQILPGVTLGAHILDTCSKDTYALEQSLEFVRASLTKVDD-SEYTCPDGSYAI-HDDVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIDAFQQEARALQICIATSAKVSRSMDQYSYDGVIRSLLQK-SNAKVVILFTRSEDARELLVAAKRMNVS--FIWVASDGWGAQEVVVRGSESVADGAFTIELASYTIPEFAAYFTNLNPYNNTRNPWFREFWENKFQC------------SLHDITCGKHSL-------------------RDGKF-------------------------EQESKIMFVVNAVYAMANALHHMRQALCANST--KLCSAMKPVNGKRLYKDYILKTKFDAPFRPADTDNIIHFDAYGDSLGRYNIFHY--HKENDEYVYRKVGYWAQD-LTLNTTLI-PWESQAVPTSQCSDPCRKNEIKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPLDNLTGCYDLPEEYIHWEDAWAIGPVSIACLGMLCTLFVIGLFLKNNETPVVKASGRELSYILLLGVLLCYFMTFIYISKPSAVVCTLRRLGLGTSFAVCYSALLTKTNRIARIFNGVKDGAQRPRFISPASQVAICAALISCQLLVVVVWLLVEAPGVRKEVSPERRDVVTLKCNSKDSSMLMSLTYNCVLIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTTLRVATTRFSVTTGPGSSFSQASASN 875          
BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Match: grm2a (glutamate receptor, metabotropic 2a [Source:ZFIN;Acc:ZDB-GENE-030131-8097])

HSP 1 Score: 688.337 bits (1775), Expect = 0.000e+0
Identity = 385/895 (43.02%), Postives = 530/895 (59.22%), Query Frame = 2
Query:  155 DNKYQSAIYNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMN 2809
            D   +  + +GD+++GGLFPVH      + C +IN  RGIQRLEAML  + +IN    ILP + +GA ILDTCSKDTYAL+QSL+F+++SL+  +D S+Y C D S  + H      I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++ L +CIA    +  +        ++++L Q+ S  +VV+LFTR +  + LL A K MN S  F+W+ASDGWG +   V  + +VA+GA T E+ +  I  F  YF  L    N+ NPWF E+WE  F C            S+  +  GK S                    RD +F                         +QESKI  V +AVYA+A  L   +  LC      K   A+  ++G   YKD I  +  D+        N++ FD+ GDS+G+YNI++Y  +K+  +Y Y+ +G +  D L LN+ +  P E + +P S CS+ C   +I+       CCW C  C+  +Y+++   C  C+ G+WP  N TGCY L   Y+      AI P+ ++ LG   T  V+G+F     TP+V+ASGRELS+++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ ICA LIS QLL   +WL    PG+R +   ++ +   LKC  +  + L+SL YN +LI +CT+YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L +++T +   T    SF+     N
Sbjct:   41 DTSKKEIVMDGDLVIGGLFPVHHKGEGAQDCGRINTQRGIQRLEAMLLALDKINQDDQILPGVTLGAHILDTCSKDTYALEQSLEFVRASLTKVDD-SEYTCPDGSYAI-HDDVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIDAFQQEARALQICIATSAKVSRSMDQYSYDGVIRSLLQK-SNAKVVILFTRSEDARELLVAAKRMNVS--FIWVASDGWGAQEVVVRGSESVADGAFTIELASYTIPEFAAYFTNLNPYNNTRNPWFREFWENKFQC------------SLHDITCGKHSL-------------------RDGKF-------------------------EQESKIMFVVNAVYAMANALHHMRQALCANST--KLCSAMKPVNGKRLYKDYILKTKFDAPFRPADTDNIIHFDAYGDSLGRYNIFHY--HKENDEYVYRKVGYWAQD-LTLNTTLI-PWESQAVPTSQCSDPCRKNEIKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPLDNLTGCYDLPEEYIHWEDAWAIGPVSIACLGMLCTLFVIGLFLKNNETPVVKASGRELSYILLLGVLLCYFMTFIYISKPSAVVCTLRRLGLGTSFAVCYSALLTKTNRIARIFNGVKDGAQRPRFISPASQVAICAALISCQLLVVVVWLLVEAPGVRKEVSPERRDVVTLKCNSKDSSMLMSLTYNCVLIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTTLRVATTRFSVTTGPGSSFSQASASN 868          
BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Match: grm3 (glutamate receptor, metabotropic 3 [Source:ZFIN;Acc:ZDB-GENE-061009-13])

HSP 1 Score: 664.07 bits (1712), Expect = 0.000e+0
Identity = 378/907 (41.68%), Postives = 536/907 (59.10%), Query Frame = 2
Query:  146 SEIDNKYQSAIYNGDIILGGLFPVHDSETEL--CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV--RKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            S  D+  +    +GD++LGGLFP+H+    +  C +IN DRGIQRLEAMLF I +IN    +LP + +G  ILDTCS+DTYAL+Q+L+F+++SL+  +D +++ C D S  L+   +   I  V+GGS+SSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++ +FNWTYVSTV S GDYG++GI+AF ++++   +CIA  E + + +   S   A+V+ L Q+    RV VLF R D  + L+ A   +N S  FLW+ASDGWG +   V  N   A+GAIT E+    I +F  YF  LT   N  NPWF ++WE         QK + S     +  +G                                   + K  C       K  NF+ ESKI  V +AVYA+A+ L R Q  LC      +   A+ ++DG   Y+D L++ +F   +      + V FD+ GD VG+YNI+NY     + K+ Y  +GE+          + WP    ++P S CS+ C   +++       CCW C+ C+  EY+ +   C  CA G+WP  + TGCY L   Y+      AI P+ ++ +G   T  V  VF  + +TP+V+ASGREL +++L G  + Y+++F+F+ KP+P  C ++R+ LG  FAV Y++LLTKTNRIARIF   ++  A+RP  ISP SQ+ IC  LISVQLL  ++WL    PG R     +K +  +LKC +   + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV   +L M+  +   P     S+A+H  +++ Y P
Sbjct:   18 SRGDSPRKEIKIDGDLVLGGLFPIHEKGMGMDECGRINEDRGIQRLEAMLFAIDQINQDVALLPGVVLGVHILDTCSRDTYALEQALEFVRASLTKVDD-TEFICPDGSYALQE-DSPLAIAGVIGGSFSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRAFNWTYVSTVASEGDYGETGIEAFEQQARLRNICIATSEKVGRSSAKRSSYEAVVRQLLQK-PTARVAVLFLRSDDARELIAAAARLNAS--FLWVASDGWGAQESIVKGNEFTADGAITLELAAHPIPDFNRYFQTLTPQINHRNPWFKDFWE---------QKFQCSLGGTSATGAG-----------------------------------TPKPPCDQELVIDK-SNFEPESKIMFVVNAVYAMAHALHRMQRTLCAN--TTRLCDAMRSLDGRKLYRDFLLHVNFRAPFSPAGLESQVKFDAYGDGVGRYNIFNYQSVPGSDKFAYVQVGEWAESLSLNEGLIGWP-RGADVPTSQCSDPCAPNEMKKMQAGEYCCWICTPCEPYEYLPDEFTCMPCAPGQWPRPDLTGCYDLPEDYIMWEDAWAIGPISIACVGFICTLMVFIVFIRHNDTPLVKASGRELCYILLLGVFMSYVMTFIFIAKPSPIVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKEGGAQRPRFISPSSQVFICLSLISVQLLLVSVWLLVEVPGTRRFTTPEKRQTVILKCNVRDSSMLMSLSYDVVLVVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNMNRFSVSGPAT---SYASHASVSAHYVP 868          
BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Match: grm3 (glutamate receptor, metabotropic 3 [Source:ZFIN;Acc:ZDB-GENE-061009-13])

HSP 1 Score: 664.07 bits (1712), Expect = 0.000e+0
Identity = 378/907 (41.68%), Postives = 536/907 (59.10%), Query Frame = 2
Query:  146 SEIDNKYQSAIYNGDIILGGLFPVHDSETEL--CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV--RKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            S  D+  +    +GD++LGGLFP+H+    +  C +IN DRGIQRLEAMLF I +IN    +LP + +G  ILDTCS+DTYAL+Q+L+F+++SL+  +D +++ C D S  L+   +   I  V+GGS+SSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++ +FNWTYVSTV S GDYG++GI+AF ++++   +CIA  E + + +   S   A+V+ L Q+    RV VLF R D  + L+ A   +N S  FLW+ASDGWG +   V  N   A+GAIT E+    I +F  YF  LT   N  NPWF ++WE         QK + S     +  +G                                   + K  C       K  NF+ ESKI  V +AVYA+A+ L R Q  LC      +   A+ ++DG   Y+D L++ +F   +      + V FD+ GD VG+YNI+NY     + K+ Y  +GE+          + WP    ++P S CS+ C   +++       CCW C+ C+  EY+ +   C  CA G+WP  + TGCY L   Y+      AI P+ ++ +G   T  V  VF  + +TP+V+ASGREL +++L G  + Y+++F+F+ KP+P  C ++R+ LG  FAV Y++LLTKTNRIARIF   ++  A+RP  ISP SQ+ IC  LISVQLL  ++WL    PG R     +K +  +LKC +   + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV   +L M+  +   P     S+A+H  +++ Y P
Sbjct:   18 SRGDSPRKEIKIDGDLVLGGLFPIHEKGMGMDECGRINEDRGIQRLEAMLFAIDQINQDVALLPGVVLGVHILDTCSRDTYALEQALEFVRASLTKVDD-TEFICPDGSYALQE-DSPLAIAGVIGGSFSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRAFNWTYVSTVASEGDYGETGIEAFEQQARLRNICIATSEKVGRSSAKRSSYEAVVRQLLQK-PTARVAVLFLRSDDARELIAAAARLNAS--FLWVASDGWGAQESIVKGNEFTADGAITLELAAHPIPDFNRYFQTLTPQINHRNPWFKDFWE---------QKFQCSLGGTSATGAG-----------------------------------TPKPPCDQELVIDK-SNFEPESKIMFVVNAVYAMAHALHRMQRTLCAN--TTRLCDAMRSLDGRKLYRDFLLHVNFRAPFSPAGLESQVKFDAYGDGVGRYNIFNYQSVPGSDKFAYVQVGEWAESLSLNEGLIGWP-RGADVPTSQCSDPCAPNEMKKMQAGEYCCWICTPCEPYEYLPDEFTCMPCAPGQWPRPDLTGCYDLPEDYIMWEDAWAIGPISIACVGFICTLMVFIVFIRHNDTPLVKASGRELCYILLLGVFMSYVMTFIFIAKPSPIVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKEGGAQRPRFISPSSQVFICLSLISVQLLLVSVWLLVEVPGTRRFTTPEKRQTVILKCNVRDSSMLMSLSYDVVLVVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNMNRFSVSGPAT---SYASHASVSAHYVP 868          
BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Match: grm3 (glutamate receptor, metabotropic 3 [Source:ZFIN;Acc:ZDB-GENE-061009-13])

HSP 1 Score: 664.07 bits (1712), Expect = 0.000e+0
Identity = 378/907 (41.68%), Postives = 536/907 (59.10%), Query Frame = 2
Query:  146 SEIDNKYQSAIYNGDIILGGLFPVHDSETEL--CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV--RKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            S  D+  +    +GD++LGGLFP+H+    +  C +IN DRGIQRLEAMLF I +IN    +LP + +G  ILDTCS+DTYAL+Q+L+F+++SL+  +D +++ C D S  L+   +   I  V+GGS+SSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++ +FNWTYVSTV S GDYG++GI+AF ++++   +CIA  E + + +   S   A+V+ L Q+    RV VLF R D  + L+ A   +N S  FLW+ASDGWG +   V  N   A+GAIT E+    I +F  YF  LT   N  NPWF ++WE         QK + S     +  +G                                   + K  C       K  NF+ ESKI  V +AVYA+A+ L R Q  LC      +   A+ ++DG   Y+D L++ +F   +      + V FD+ GD VG+YNI+NY     + K+ Y  +GE+          + WP    ++P S CS+ C   +++       CCW C+ C+  EY+ +   C  CA G+WP  + TGCY L   Y+      AI P+ ++ +G   T  V  VF  + +TP+V+ASGREL +++L G  + Y+++F+F+ KP+P  C ++R+ LG  FAV Y++LLTKTNRIARIF   ++  A+RP  ISP SQ+ IC  LISVQLL  ++WL    PG R     +K +  +LKC +   + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV   +L M+  +   P     S+A+H  +++ Y P
Sbjct:   18 SRGDSPRKEIKIDGDLVLGGLFPIHEKGMGMDECGRINEDRGIQRLEAMLFAIDQINQDVALLPGVVLGVHILDTCSRDTYALEQALEFVRASLTKVDD-TEFICPDGSYALQE-DSPLAIAGVIGGSFSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRAFNWTYVSTVASEGDYGETGIEAFEQQARLRNICIATSEKVGRSSAKRSSYEAVVRQLLQK-PTARVAVLFLRSDDARELIAAAARLNAS--FLWVASDGWGAQESIVKGNEFTADGAITLELAAHPIPDFNRYFQTLTPQINHRNPWFKDFWE---------QKFQCSLGGTSATGAG-----------------------------------TPKPPCDQELVIDK-SNFEPESKIMFVVNAVYAMAHALHRMQRTLCAN--TTRLCDAMRSLDGRKLYRDFLLHVNFRAPFSPAGLESQVKFDAYGDGVGRYNIFNYQSVPGSDKFAYVQVGEWAESLSLNEGLIGWP-RGADVPTSQCSDPCAPNEMKKMQAGEYCCWICTPCEPYEYLPDEFTCMPCAPGQWPRPDLTGCYDLPEDYIMWEDAWAIGPISIACVGFICTLMVFIVFIRHNDTPLVKASGRELCYILLLGVFMSYVMTFIFIAKPSPIVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKEGGAQRPRFISPSSQVFICLSLISVQLLLVSVWLLVEVPGTRRFTTPEKRQTVILKCNVRDSSMLMSLSYDVVLVVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNMNRFSVSGPAT---SYASHASVSAHYVP 868          
BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Match: GRM8 (glutamate receptor, metabotropic 8 [Source:NCBI gene;Acc:100497088])

HSP 1 Score: 637.876 bits (1644), Expect = 0.000e+0
Identity = 363/896 (40.51%), Postives = 508/896 (56.70%), Query Frame = 2
Query:   98 PIVIYYSFFV--TVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFP-------VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            P +++ + ++    +++ +    +Y  +I   GDIILGGLFPVH        C  +  ++GI RLEAM++ I +IN   D+LPNI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  ++R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA    I   P   +   I++ L  E    R +++F   D  + +L A K  N + +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   +   N  N WF E+WEE F C              K    GK                            R+N  K     CT      +  +F+QE K+Q V DAVY++A+ L+     LC P  +  C + +  IDG      +   +F  S G  V+F+ NGD+ G+Y+IY Y    KT +Y  K IG++ +  L LN E + W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC L+ +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P  + C+++RI LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQL+   IW    PP I  D  +   P       VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL IS+SLSA V+L  L+ PK++II L PE+NV+K
Sbjct:   19 PCILFLTMYILGISSMMQTTNGQEYAHSIRVEGDIILGGLFPVHARGERGVPCGDLKKEKGIHRLEAMMYAIDQINKDSDLLPNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVRCANGDPPI-FTKP-DKIVGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNSRYDFYSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQLSREIGGVCIAQSLKIPREPKVGEFDKIIRRLL-ETPNARAIIIFANEDDIRRILEAAKRNNQTGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRSLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNNHFKK----CTGLERIGRHSSFEQEGKVQFVIDAVYSMAHALNNMHKDLC-PGYIGLCPR-MKTIDGKELLSYIRAVNFNGSAGTPVTFNENGDAPGRYDIYQYQMTNKTAEY--KVIGQWTNQ-LHLNVEDMQWTSREHTQPTSVCSLPCKPGERKKTVKGVPCCWHCERCEGYHYQVDELTCELCPLDQKPNANRTGCQLIPIIKLEWHSPWAVVPVFIAILGIVATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYAITFLMIGTPDMFVCSLRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLIGVFIWFVVDPPHIIIDYGEQRTPDPINARGVLKCDISELSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAERMYIQTTTLTISMSLSASVSLGMLYMPKVYIIILHPEQNVQK 858          
BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Match: GRM8 (glutamate receptor, metabotropic 8 [Source:NCBI gene;Acc:100497088])

HSP 1 Score: 637.491 bits (1643), Expect = 0.000e+0
Identity = 363/896 (40.51%), Postives = 508/896 (56.70%), Query Frame = 2
Query:   98 PIVIYYSFFV--TVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFP-------VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            P +++ + ++    +++ +    +Y  +I   GDIILGGLFPVH        C  +  ++GI RLEAM++ I +IN   D+LPNI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  ++R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA    I   P   +   I++ L  E    R +++F   D  + +L A K  N + +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   +   N  N WF E+WEE F C              K    GK                            R+N  K     CT      +  +F+QE K+Q V DAVY++A+ L+     LC P  +  C + +  IDG      +   +F  S G  V+F+ NGD+ G+Y+IY Y    KT +Y  K IG++ +  L LN E + W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC L+ +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P  + C+++RI LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQL+   IW    PP I  D  +   P       VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL IS+SLSA V+L  L+ PK++II L PE+NV+K
Sbjct:   17 PCILFLTMYILGISSMMQTTNGQEYAHSIRVEGDIILGGLFPVHARGERGVPCGDLKKEKGIHRLEAMMYAIDQINKDSDLLPNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVRCANGDPPI-FTKP-DKIVGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNSRYDFYSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQLSREIGGVCIAQSLKIPREPKVGEFDKIIRRLL-ETPNARAIIIFANEDDIRRILEAAKRNNQTGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRSLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNNHFKK----CTGLERIGRHSSFEQEGKVQFVIDAVYSMAHALNNMHKDLC-PGYIGLCPR-MKTIDGKELLSYIRAVNFNGSAGTPVTFNENGDAPGRYDIYQYQMTNKTAEY--KVIGQWTNQ-LHLNVEDMQWTSREHTQPTSVCSLPCKPGERKKTVKGVPCCWHCERCEGYHYQVDELTCELCPLDQKPNANRTGCQLIPIIKLEWHSPWAVVPVFIAILGIVATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYAITFLMIGTPDMFVCSLRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLIGVFIWFVVDPPHIIIDYGEQRTPDPINARGVLKCDISELSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAERMYIQTTTLTISMSLSASVSLGMLYMPKVYIIILHPEQNVQK 856          
BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Match: GRM2 (glutamate receptor, metabotropic 2 [Source:NCBI gene;Acc:100380092])

HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0
Identity = 377/892 (42.26%), Postives = 512/892 (57.40%), Query Frame = 2
Query:  182 NGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQN-------QNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSY-----GNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRK--KPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTN---SSGSFANH 2797
            +GD ++GGLFPVH+  +    C ++N  RG+QRLEAMLF +  INN P +LP + +GA ILDTCSKDTYAL+Q+L+ ++ SL+   D   + C D S  + H ++   I  V+GGSYS VSI VANLLRLF I QISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  +        ++K L Q+ S  RVVVLFT+++  + LL A + +N S  F W+ASDGWG     V  +  VA GAI     T+E+ ++                                            LM   E   YF +   D N +N       +N F      P   S  S +Q+            F+QESKI  V +AVYA+A+ L   Q  +C           +N  +G  FY+D ++N  F   +      + V FD  GD +G+YNI+N+      G+Y+Y+ +G +  + L LN+ +  P  +  +P S CS+ C   +++       CCW C  C+  E++V+   C+ C  G WP  + TGCY L   Y++     A+ P+ LS LG  +T  V+GVF    NTPIV+ASGREL +++L G L+CY ++F+F+ KP+   C ++R+ LG  FA+ Y++LLTKTNRIARIF  A+   +RP  ISP SQ+ IC VLIS QLL   IWL F PPG R D    K     LKC     + L+SL YN+LL+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ IY+ T   + VQ +TL +SVSLS  V L CLF PKLHII  QP+KNV       T++R  TN   ++G    H
Sbjct:   30 DGDFVIGGLFPVHEKGAPGAECGRMNEHRGLQRLEAMLFALDAINNDPHLLPGLQLGAHILDTCSKDTYALEQALELVRGSLT-RTDGPQHLCPDGSYAI-HGESPTAISGVIGGSYSDVSIQVANLLRLFQIAQISYASTSAKLSDKSRYDFFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIEAFEQEARARNICIATSEKVGRSMNKKTFAGVIKALQQKPS-ARVVVLFTKIEDARELLAAAQELNVS--FTWVASDGWGALESVVLGSEQVAEGAI-----TIELASY-------------------------------------------PLMEFSE---YFQSLHPDNNTRNPWFREFWENKFQCSLTSP-GCSEHSLRQV-----------KFEQESKIMFVVNAVYAMAHALHNMQHAVC--LNSTYLCPNMNPPNGKRFYRDYILNVKFNAPFPPPDTKSTVRFDKYGDGIGRYNIFNF--QNTGGRYHYQKVGYWAEE-LTLNTSLI-PWAKSAVPVSQCSDPCKKNEVKSMQPGDVCCWICISCQPYEFLVDEFTCKDCGLGYWPNLDLTGCYELPQEYIRWGDAWAVGPVCLSCLGLLSTLFVIGVFVQNNNTPIVKASGRELCYILLCGVLLCYAMTFIFISKPSTSVCTLRRLGLGTSFAICYSALLTKTNRIARIFSGARDGVQRPRFISPASQVGICLVLISCQLLVVLIWLLFEPPGTRKDTAPDKRYIVTLKCNSGDGSMLISLSYNVLLVLLCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIYYVTSSDYRVQTTTLCVSVSLSGSVVLGCLFTPKLHIIIFQPQKNV-------TSHRIATNRFSATGPGGTH 840          
BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Match: xylt1 (xylosyltransferase I [Source:Xenbase;Acc:XB-GENE-949399])

HSP 1 Score: 627.091 bits (1616), Expect = 0.000e+0
Identity = 370/889 (41.62%), Postives = 504/889 (56.69%), Query Frame = 2
Query:  185 GDIILGGLFPVHDSETE--LCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFT-RLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKK----PEFP--VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK-----------LTMSSTTYRKPTN 2773
            GDI LGGLFPVH        C  I  + GI RLEAML+ + +IN+ PDILPN+ +GARILDTCS+DTYAL+QSL F+++ +    D SD  C +    +      +K+  V+G S SSVSI+VAN+LRLF IPQISY ST+  LS+ + +  F+R +P D  QA+AM ++V +  W YVST+ S G YG+ G+++F + S++ G VCIA    I      SD   I+K L  E S  R VVLF    D  + +L+AVK  +   +F W+ SD WG + GP+  N +VA GAIT   K   I+ F  YF   T   N  N WF E+WEE F+C     K+ ++ S        KE         TD     Q    +D                           ++Q+ ++Q V DAVYA+A+ L      LC P     C + + +  G    K + N SF  S G  V F+ NGD++G+Y+++ Y I N  T  Y  + IG++  D L LN E + W    +EIP S+CS  C +G+ +   K   CCW C LC   +Y+ +   C +C     P +NRTGC  + +  ++     A+IP+ L+ LG   T  VM  F  Y +TPIVRASGRELS+++L+G  +CY+++F+ + KP    C+ +RI LGLG  + YA+LLTKTNRI RIFE  +K+   P  ISP SQL I + LISVQLL   IW   +PP I  D  +    PE    VLKC I     + SL Y++LL+  CT YAIKTR +PENFNE+K IGFTMYTTC++WLAFI I+FGT  S E   +Q +TL IS++LSA V L  L+ PK++II   PE NV+K            TMS+    KP++
Sbjct:   43 GDITLGGLFPVHSRGLPGMPCGDIRKENGIHRLEAMLYALDQINSDPDILPNVTLGARILDTCSRDTYALEQSLTFVQALI--QKDTSDVRCTNGDPPV--FVKPEKVVGVIGASESSVSIMVANILRLFQIPQISYGSTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKAMGWNYVSTLASEGSYGEKGVESFMQISREAGGVCIAQSLKIPYERTTSDFDKIIKQLL-ETSSARAVVLFAVDDDDIRQVLSAVKRADKVGHFHWVGSDTWGAKVGPIIQNEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEFWEENFNC-----KLTITGSK-------KED--------TDRKCTGQERIGQD-------------------------SLYEQDERVQFVVDAVYAMAHALHNMNKDLC-PGSTGICPE-MEHAGGKKLLKYIRNVSFNGSAGTPVMFNKNGDALGRYDLFQYQITNGSTQGY--RLIGQWT-DELQLNIEDMQWAKGPREIPPSVCSLPCMMGERKKMVKGMPCCWNCELCDGYKYLRDEFTCNLCDYNMRPNKNRTGCDSIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVLIWFGVTPPSIIIDYGQHTVTPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSTRLSHKPSD 876          
BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Match: xylt1 (xylosyltransferase I [Source:Xenbase;Acc:XB-GENE-949399])

HSP 1 Score: 627.091 bits (1616), Expect = 0.000e+0
Identity = 370/890 (41.57%), Postives = 504/890 (56.63%), Query Frame = 2
Query:  182 NGDIILGGLFPVHDSETE--LCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFT-RLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKK----PEFP--VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK-----------LTMSSTTYRKPTN 2773
             GDI LGGLFPVH        C  I  + GI RLEAML+ + +IN+ PDILPN+ +GARILDTCS+DTYAL+QSL F+++ +    D SD  C +    +      +K+  V+G S SSVSI+VAN+LRLF IPQISY ST+  LS+ + +  F+R +P D  QA+AM ++V +  W YVST+ S G YG+ G+++F + S++ G VCIA    I      SD   I+K L  E S  R VVLF    D  + +L+AVK  +   +F W+ SD WG + GP+  N +VA GAIT   K   I+ F  YF   T   N  N WF E+WEE F+C     K+ ++ S        KE         TD     Q    +D                           ++Q+ ++Q V DAVYA+A+ L      LC P     C + + +  G    K + N SF  S G  V F+ NGD++G+Y+++ Y I N  T  Y  + IG++  D L LN E + W    +EIP S+CS  C +G+ +   K   CCW C LC   +Y+ +   C +C     P +NRTGC  + +  ++     A+IP+ L+ LG   T  VM  F  Y +TPIVRASGRELS+++L+G  +CY+++F+ + KP    C+ +RI LGLG  + YA+LLTKTNRI RIFE  +K+   P  ISP SQL I + LISVQLL   IW   +PP I  D  +    PE    VLKC I     + SL Y++LL+  CT YAIKTR +PENFNE+K IGFTMYTTC++WLAFI I+FGT  S E   +Q +TL IS++LSA V L  L+ PK++II   PE NV+K            TMS+    KP++
Sbjct:   42 EGDITLGGLFPVHSRGLPGMPCGDIRKENGIHRLEAMLYALDQINSDPDILPNVTLGARILDTCSRDTYALEQSLTFVQALI--QKDTSDVRCTNGDPPV--FVKPEKVVGVIGASESSVSIMVANILRLFQIPQISYGSTAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKAMGWNYVSTLASEGSYGEKGVESFMQISREAGGVCIAQSLKIPYERTTSDFDKIIKQLL-ETSSARAVVLFAVDDDDIRQVLSAVKRADKVGHFHWVGSDTWGAKVGPIIQNEDVAEGAITILPKRATIEGFDAYFTSRTLENNRRNVWFAEFWEENFNC-----KLTITGSK-------KED--------TDRKCTGQERIGQD-------------------------SLYEQDERVQFVVDAVYAMAHALHNMNKDLC-PGSTGICPE-MEHAGGKKLLKYIRNVSFNGSAGTPVMFNKNGDALGRYDLFQYQITNGSTQGY--RLIGQWT-DELQLNIEDMQWAKGPREIPPSVCSLPCMMGERKKMVKGMPCCWNCELCDGYKYLRDEFTCNLCDYNMRPNKNRTGCDSIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRIFLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVLIWFGVTPPSIIIDYGQHTVTPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSTRLSHKPSD 876          
BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Match: Grm3 (glutamate receptor, metabotropic 3 [Source:MGI Symbol;Acc:MGI:1351340])

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 379/897 (42.25%), Postives = 542/897 (60.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG------NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVR---------KLTMSSTTYRKPTNSS--GSFANHREM 2806
            GD++LGGLFP+++  + TE C +IN DRGIQRLEAMLF I EIN    +LP + +G  ILDTCS+DTYAL+QSL+F+++SL+  ++A +Y C D S  ++       I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  + +     ++++ L Q+    RVVVLF R D ++ L+ A   +N S  F W+ASDGWG +   V  + +VA GAIT E+ +  ++ F  YF  L    N  NPWF ++WE+ F C               SL                 NK+N    HR              Q+C   + +    N++QESKI  V +AVYA+A+ L + Q  LC P   + C  A+  +DG   YKD L+  +FT  +       ++V FD+ GD +G+YN++N+      GKY Y  +G +  + L+L+ + + W      +P S CS+ C   +++       CCW C  C+  EY+V+   C  C  G+WP  + +GCY L   Y++     AI P+ ++ LG   T  V+ VF  + NTP+V+ASGREL +++L G  + Y ++F F+ KP+P  CA++R+ LG  FA+ Y++LLTKTN IARIF+  +  A+RP  ISP SQ+ IC  LI VQ++  ++WL    PG R     +K E  +LKC ++  + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L CLF PK+HI+  QP+KNV           ++ ++TTY + + S+   +  N RE+
Sbjct:   37 GDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEA-EYMCPDGSYAIQENIPLL-IAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PNARVVVLFMRSDDSRELIAAASRVNAS--FTWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC---------------SLQ----------------NKRN----HR--------------QICDK-HLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLC-PNTTKLC-DAMKILDGKKLYKDYLLKINFTAPFNPNKGADSIVKFDTYGDGMGRYNVFNF--QHIGGKYSYLKVGHWA-ETLYLDVDSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPTADLSGCYNLPEDYIRWEDAWAIGPVTIACLGFMCTCIVITVFIKHNNTPLVKASGRELCYILLFGVSLSYCMTFFFIAKPSPVICALRRLGLGTSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILETPGTRRYTLPEKRETVILKCNVKDSSMLISLTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIVLFQPQKNVVTHRLHLNRFSVSGTATTYSQSSASTYVPTVCNGREV 871          
BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Match: Grm2 (glutamate receptor, metabotropic 2 [Source:MGI Symbol;Acc:MGI:1351339])

HSP 1 Score: 668.307 bits (1723), Expect = 0.000e+0
Identity = 380/888 (42.79%), Postives = 509/888 (57.32%), Query Frame = 2
Query:  182 NGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVT-WPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMN 2809
             GD++LGGLFPVH      E C  +N  RGIQRLEAMLF +  IN  P +LP + +GA ILD+CSKDT+AL+Q+LDF+++SLS   D S + C D S     + A   I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF  E++   +C+A  E +      +    +V+ L Q+ S  RV VLFTR +  + LL A + +N S  F W+ASDGWG     V  +   A GAIT E+ +  I +F +YF  L    NS NPWF E+WEE                              F  +F    +Q   + H     P                       F+QESKI  V +AVYA+A+ L      LC P     C  A+  ++G   YKD + N   D+        + V FD  GD +G+YNI+ Y+R    G+Y Y+ +G +  +GL L++ +  W       +P S CSE C   +++       CCW C  C+  EY ++   C  C  G WP  + TGC+ L   Y++     A+ P+ ++ LG   T  V+GVF  +  TP+V+ASGREL +++L G  +CY ++F+F+ KP+   C ++R+ LG  F+V Y++LLTKTNRIARIF  A++ A+RP  ISP SQ+ IC  LIS QLL  A WL    PGI  +   ++ E   L+C     + L SL YN+LLI++CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ +SVSLS  V L CLF PKLHII  QP+KNV        ++R PT+  GS A     N
Sbjct:   29 EGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYAT-LSDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPS-ARVAVLFTRSEDARELLAATQRLNAS--FTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQNLDPWNNSRNPWFREFWEE-----------------------------RFRCSF----RQRDCAAHSLRAVP-----------------------FEQESKIMFVVNAVYAMAHALHNMHRALC-PNTTRLC-DAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLR-AGNGRYRYQKVG-YWAEGLTLDTSIIPWASPSAGTLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGIGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNV-------VSHRAPTSRFGSAAPRASAN 845          
BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Match: Grm8 (glutamate receptor, metabotropic 8 [Source:MGI Symbol;Acc:MGI:1351345])

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 360/886 (40.63%), Postives = 501/886 (56.55%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPG--IRYDRKKPEFP-----VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C  +  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L     +LC P  +  C + +  IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y  N K+ +Y  K IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC  + +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +RI LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP   I Y  ++   P     VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRLDGDIILGGLFPVHAKGERGVPCGDLKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKELC-PGYIGLCPRMVT-IDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEY--KIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Match: Grm8 (glutamate receptor, metabotropic 8 [Source:MGI Symbol;Acc:MGI:1351345])

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 360/886 (40.63%), Postives = 501/886 (56.55%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPG--IRYDRKKPEFP-----VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C  +  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L     +LC P  +  C + +  IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y  N K+ +Y  K IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC  + +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +RI LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP   I Y  ++   P     VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRLDGDIILGGLFPVHAKGERGVPCGDLKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKELC-PGYIGLCPRMVT-IDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEY--KIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Match: Grm8 (glutamate receptor, metabotropic 8 [Source:MGI Symbol;Acc:MGI:1351345])

HSP 1 Score: 634.41 bits (1635), Expect = 0.000e+0
Identity = 360/886 (40.63%), Postives = 501/886 (56.55%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAI-YNGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPG--IRYDRKKPEFP-----VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE---VQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            F+  + ++      +Y  +I  +GDIILGGLFPVH        C  +  ++GI RLEAML+ I +IN  PD+L NI +G RILDTCS+DTYAL+QSL F+++ +    DASD  C +    +  TK   KI  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM ++V +  W YVST+ S G+YG+SG++AF + S+++G VCIA  + I   P   +   I+K L  E    R V++F   D  + +L A K +N S +FLWI SD WG +  PV     +A GA+T   K   I  F  YF   T   N  N WF E+WEE F C              K    GK                            R++ +K     CT     ++  +++QE K+Q V DAVY++AY L     +LC P  +  C + +  IDG      +   +F  S G  V+F+ NGD+ G+Y+I+ Y  N K+ +Y  K IG + +       ++ W   E   P S+CS  C  G+ +   K   CCW C  C+   Y V+   CE+C   + P  NRTGC  + +  ++     A++P+ ++ LG   TT V+  F  Y +TPIVRASGRELS+++L+G  +CY ++F+ +  P    C+ +RI LGLG    YA+LLTKTNRI RIFE  +K+   P  ISP SQL+I   LISVQLL   +W    PP   I Y  ++   P     VLKC I   + + SL Y++LL+  CT YAIKTR +PE FNE+K IGFTMYTTC+IWLAFI I+FGT  S E   +Q +TL +S+SLSA V+L  L+ PK++II   PE+NV+K
Sbjct:   21 FYWILTMMQRTHSQEYAHSIRLDGDIILGGLFPVHAKGERGVPCGDLKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI--EKDASDVKCANGDPPI-FTKP-DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-ETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGC--------------KLGSHGK----------------------------RNSHIKK----CTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKELC-PGYIGLCPRMVT-IDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINNKSTEY--KIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHTIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQK 851          
BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Match: sp|P91685|GRM_DROME (Metabotropic glutamate receptor OS=Drosophila melanogaster OX=7227 GN=mGluR PE=1 SV=2)

HSP 1 Score: 746.117 bits (1925), Expect = 0.000e+0
Identity = 421/939 (44.83%), Postives = 569/939 (60.60%), Query Frame = 2
Query:  185 GDIILGGLFPVHD-SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSE-VLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC-----------KPFVLE-------------KCVKALNNIDGMVFYKD-LINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY---DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMNSEYTPLPPPFNSQSHHLVVVSIQSHS--PSINEP 2905
            GDIILGGLFPVH+  E   C     +RG+QRLEAML+ I  +NN P+ILP I IG  ILDTCS+DTYAL QSL F+++SL +N D S Y C D S   LR   ++  +  V+GGSYSSVS+ VANLLRLF IPQ+S AST+  LS+K    +FART+P D  Q+ A+ +++ +FNW+YVST+ S G YG+ GI+A  KE+ +  VCIA  E + P+     +   + +  Q+    R VVLFTR +  + +L A K  N S  F WIASDGWG++   +    ++A GAIT E+++  I +F  Y  QLT   N  NPWF EYWE+ F+C+       ++  SVK   S          N TD NK                 VK++ +    +  S K+  ++QESK Q V DAVYA AY L    +  C           K    E             +    + N DG  FY + L+N SF D  G+ V FD  GD + +Y+I NY R + +  Y YK IG++  +GL LNSE     +E E P S CS  C VG I+    ++ CCW C  C+S EYV +   C+ C  G WPY ++  CY L + YMK +   A+IPM ++  G A T+ V+ +F    +TP+VRASGRELS+ +L G LVCY  +F  + KPT  SC +QR  +G+GF+++Y++LLTKTNRI+RIF SA K+A+R   ISP+SQ++I   LI++Q+L   IW+   PPG R+   DR++    +LKCKI+  +FL S +YNM+LI++CT YAIKTRKIPENFNESKFIGFTMYTTC+IWLAF+ IYFGT +S+EVQ +TL IS+SLSA V L+CL+ PK++I+   P+KNVRKLTM+ST YR+   S+ + A     +S Y+    P  S      V +  S S  P+ N P
Sbjct:   43 GDIILGGLFPVHEKGEGAPCGPKVYNRGVQRLEAMLYAIDRVNNDPNILPGITIGVHILDTCSRDTYALNQSLQFVRASL-NNLDTSGYECADGSSPQLRKNASSGPVFGVIGGSYSSVSLQVANLLRLFHIPQVSPASTAKTLSDKTRFDLFARTVPPDTFQSVALVDILKNFNWSYVSTIHSEGSYGEYGIEALHKEATERNVCIAVAEKV-PSAADDKVFDSIISKLQKKPNARGVVLFTRAEDARRILQAAKRANLSQPFHWIASDGWGKQQKLLEGLEDIAEGAITVELQSEIIADFDRYMMQLTPETNQRNPWFAEYWEDTFNCV-------LTSLSVKPDTSNS-------ANSTD-NKIG---------------VKAKTECDDSYRLSEKV-GYEQESKTQFVVDAVYAFAYALHNLHNDRCNTQSDQTTETRKHLQSESVWYRKISTDTKSQACPDMANYDGKEFYNNYLLNVSFIDLAGSEVKFDRQGDGLARYDILNYQRQENSSGYQYKVIGKW-FNGLQLNSETVVWNKETEQPTSACSLPCEVGMIKKQQGDT-CCWICDSCESFEYVYDEFTCKDCGPGLWPYADKLSCYALDIQYMKWNSLFALIPMAIAIFGIALTSIVIVLFAKNHDTPLVRASGRELSYTLLFGILVCYCNTFALIAKPTIGSCVLQRFGIGVGFSIIYSALLTKTNRISRIFHSASKSAQRLKYISPQSQVVITTSLIAIQVLITMIWMVVEPPGTRFYYPDRRE---VILKCKIQDMSFLFSQLYNMILITICTIYAIKTRKIPENFNESKFIGFTMYTTCIIWLAFVPIYFGTGNSYEVQTTTLCISISLSASVALVCLYSPKVYILVFHPDKNVRKLTMNSTVYRR---SAAAVAQGAPTSSGYSRTHAPGTSALTGGAVGTNASSSTLPTQNSP 940          
BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Match: sp|P31421|GRM2_RAT (Metabotropic glutamate receptor 2 OS=Rattus norvegicus OX=10116 GN=Grm2 PE=1 SV=1)

HSP 1 Score: 674.855 bits (1740), Expect = 0.000e+0
Identity = 381/888 (42.91%), Postives = 511/888 (57.55%), Query Frame = 2
Query:  182 NGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEK-EIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMN 2809
             GD++LGGLFPVH      E C  +N  RGIQRLEAMLF +  IN  P +LP + +GA ILD+CSKDT+AL+Q+LDF+++SLS   D S + C D S    H+ A   +  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF  E++   +C+A  E +      +    +V+ L Q+ S  RV VLFTR +  + LL A + +N S  F W+ASDGWG     V  +   A GAIT E+ +  I +F +YF  L    NS NPWF E+WEE                              FH +F    +Q   + H     P                       F+QESKI  V +AVYA+A+ L      LC P     C  A+  ++G   YKD + N   D+        + V FD  GD +G+YNI+ Y+R   +G+Y Y+ +G +  +GL L++  + W       +P S CSE C   +++       CCW C  C+  EY ++   C  C  G WP  + TGC+ L   Y++     A+ P+ ++ LG   T  V+GVF  +  TP+V+ASGREL +++L G  +CY ++FVF+ KP+   C ++R+ LG  F+V Y++LLTKTNRIARIF  A++ A+RP  ISP SQ+ IC  LIS QLL  A WL    PG   +   ++ E   L+C     + L SL YN+LLI++CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ +SVSLS  V L CLF PKLHII  QP+KNV        ++R PT+  GS A     N
Sbjct:   29 EGDLVLGGLFPVHQKGGPAEECGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYAT-HSDAPTAVTGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPS-ARVAVLFTRSEDARELLAATQRLNAS--FTWVASDGWGALESVVAGSERAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEE-----------------------------RFHCSF----RQRDCAAHSLRAVP-----------------------FEQESKIMFVVNAVYAMAHALHNMHRALC-PNTTHLC-DAMRPVNGRRLYKDFVLNVKFDAPFRPADTDDEVRFDRFGDGIGRYNIFTYLR-AGSGRYRYQKVG-YWAEGLTLDTSFIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFVFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVAAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNV-------VSHRAPTSRFGSAAPRASAN 845          
BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Match: sp|Q9QYS2|GRM3_MOUSE (Metabotropic glutamate receptor 3 OS=Mus musculus OX=10090 GN=Grm3 PE=1 SV=1)

HSP 1 Score: 671.389 bits (1731), Expect = 0.000e+0
Identity = 379/897 (42.25%), Postives = 542/897 (60.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG------NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVR---------KLTMSSTTYRKPTNSS--GSFANHREM 2806
            GD++LGGLFP+++  + TE C +IN DRGIQRLEAMLF I EIN    +LP + +G  ILDTCS+DTYAL+QSL+F+++SL+  ++A +Y C D S  ++       I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  + +     ++++ L Q+    RVVVLF R D ++ L+ A   +N S  F W+ASDGWG +   V  + +VA GAIT E+ +  ++ F  YF  L    N  NPWF ++WE+ F C               SL                 NK+N    HR              Q+C   + +    N++QESKI  V +AVYA+A+ L + Q  LC P   + C  A+  +DG   YKD L+  +FT  +       ++V FD+ GD +G+YN++N+      GKY Y  +G +  + L+L+ + + W      +P S CS+ C   +++       CCW C  C+  EY+V+   C  C  G+WP  + +GCY L   Y++     AI P+ ++ LG   T  V+ VF  + NTP+V+ASGREL +++L G  + Y ++F F+ KP+P  CA++R+ LG  FA+ Y++LLTKTN IARIF+  +  A+RP  ISP SQ+ IC  LI VQ++  ++WL    PG R     +K E  +LKC ++  + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L CLF PK+HI+  QP+KNV           ++ ++TTY + + S+   +  N RE+
Sbjct:   37 GDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEA-EYMCPDGSYAIQENIPLL-IAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PNARVVVLFMRSDDSRELIAAASRVNAS--FTWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC---------------SLQ----------------NKRN----HR--------------QICDK-HLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLC-PNTTKLC-DAMKILDGKKLYKDYLLKINFTAPFNPNKGADSIVKFDTYGDGMGRYNVFNF--QHIGGKYSYLKVGHWA-ETLYLDVDSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPTADLSGCYNLPEDYIRWEDAWAIGPVTIACLGFMCTCIVITVFIKHNNTPLVKASGRELCYILLFGVSLSYCMTFFFIAKPSPVICALRRLGLGTSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILETPGTRRYTLPEKRETVILKCNVKDSSMLISLTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIVLFQPQKNVVTHRLHLNRFSVSGTATTYSQSSASTYVPTVCNGREV 871          
BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Match: sp|Q1ZZH1|GRM3_MACFA (Metabotropic glutamate receptor 3 OS=Macaca fascicularis OX=9541 GN=GRM3 PE=2 SV=1)

HSP 1 Score: 669.848 bits (1727), Expect = 0.000e+0
Identity = 370/859 (43.07%), Postives = 519/859 (60.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG------NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV 2728
            GD++LGGLFP+ +  + TE C +IN DRGIQRLEAMLF I EIN    +LP + +G  ILDTCS+DTYAL+QSL+F+++SL+  ++A +Y C D S  ++       I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  + +     ++++ L Q+    RVVVLF R D ++ L+ A    N S  F W+ASDGWG +   +  + +VA GAIT E+ +  ++ F  YF  L    N  NPWF ++WE+ F C               SL                 NK+N    HR              ++C   + +    N++QESKI  V +AVYA+A+ L + Q  LC P   + C  A+  +DG   YKD L+  +FT  +       ++V FD+ GD +G+YN++N+      GKY Y  +G +        + + W      +P S CS+ C   +++       CCW C  C+S EY+ +   C  C  G+WP  + TGCY L   Y++     AI P+ ++ LG   T  V+ VF  + NTP+V+ASGREL +++L G  + Y ++F F+ KP+P  CA++R+ LG  FA+ Y++LLTKTN IARIF+  +  A+RP  ISP SQ+ IC  LI VQ++  ++WL    PG R     +K E  +LKC ++  + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L CLF PK+HII  QP+KNV
Sbjct:   37 GDLVLGGLFPIKEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEA-EYMCPDGSYAIQENIPLL-IAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PNARVVVLFMRSDDSRELIAAASRANAS--FTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC---------------SLQ----------------NKRN----HR--------------RVCDK-HLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLC-PNTTKLC-DAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNF--QNVGGKYSYLKVGHWAETLSLDVNSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCESYEYLADEFTCMDCGPGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVITVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNV 834          
BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Match: sp|Q14832|GRM3_HUMAN (Metabotropic glutamate receptor 3 OS=Homo sapiens OX=9606 GN=GRM3 PE=1 SV=2)

HSP 1 Score: 669.078 bits (1725), Expect = 0.000e+0
Identity = 369/859 (42.96%), Postives = 519/859 (60.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG------NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY--DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV 2728
            GD++LGGLFP+++  + TE C +IN DRGIQRLEAMLF I EIN    +LP + +G  ILDTCS+DTYAL+QSL+F+++SL+  ++A +Y C D S  ++       I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  + +     ++++ L Q+    RVVVLF R D ++ L+ A    N S  F W+ASDGWG +   +  + +VA GAIT E+ +  ++ F  YF  L    N  NPWF ++WE+ F C               SL                 NK+N    HR              ++C   + +    N++QESKI  V +AVYA+A+ L + Q  LC P   + C  A+  +DG   YKD L+  +FT  +       ++V FD+ GD +G+YN++N+      GKY Y  +G +        + + W      +P S CS+ C   +++       CCW C  C+  EY+ +   C  C  G+WP  + TGCY L   Y++     AI P+ ++ LG   T  V+ VF  + NTP+V+ASGREL +++L G  + Y ++F F+ KP+P  CA++R+ LG  FA+ Y++LLTKTN IARIF+  +  A+RP  ISP SQ+ IC  LI VQ++  ++WL    PG R     +K E  +LKC ++  + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L CLF PK+HII  QP+KNV
Sbjct:   37 GDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKVDEA-EYMCPDGSYAIQENIPLL-IAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATAEKVGRSNIRKSYDSVIRELLQK-PNARVVVLFMRSDDSRELIAAASRANAS--FTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQC---------------SLQ----------------NKRN----HR--------------RVCDK-HLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLC-PNTTKLC-DAMKILDGKKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNF--QNVGGKYSYLKVGHWAETLSLDVNSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLADEFTCMDCGSGQWPTADLTGCYDLPEDYIRWEDAWAIGPVTIACLGFMCTCMVVTVFIKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSALLTKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILEAPGTRRYTLAEKRETVILKCNVKDSSMLISLTYDVILVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIILFQPQKNV 834          
BLAST of Metabotropic glutamate receptor vs. TrEMBL
Match: A0A0X3PCU6 (Metabotropic glutamate receptor OS=Schistocephalus solidus OX=70667 GN=GRM PE=3 SV=1)

HSP 1 Score: 919.072 bits (2374), Expect = 0.000e+0
Identity = 468/890 (52.58%), Postives = 606/890 (68.09%), Query Frame = 2
Query:  173 AIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSD-------NNDASDYYCKDK----SEVLRHTKATQK------IRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLK-NFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPF-------VLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRK 2764
            A   GDIILGGLFPVH S    C+ +NP+RGIQR+EAMLFT+ EINN P++LP + +GA I DTCS   +AL+QSLDF+K++++D        + ++D  C       S  +  T A         +R VVGGSYS+VSILVANL RLF +PQISYASTSA+LS+K+ +P+FART+PSD +QA+AMA+LVA+ NWTYVSTVRS+GDYGDSG+DAFWKE+ K GVCIAA+E+I+ +    DL  +VK L   FSK RVVVLFTR+DHTKLLLNAV+  N +++F+WIASDGWG+EN PV NNS VANGA+T E+   EI  F+ Y+  L  + N+ NPWF +YWE LF C                        Y   +N  + +  + N      R P   S    +          KL   FKQE+KIQ VYDA+YA A+ L + Q  LC PF         ++C++ L +  G  FY  +I  SF D+YGNLV+FD NGD VGQY IYNY R+  TG+Y Y+ +G+++   L + S   WPG + + +P S CSE+CP G +R YSK+ +CCW C  C++N+ ++N+T CE C +  WP  NRT C  L +HY+K + W AIIPMIL+ +G   T  V+     Y  TPIVRA+GREL++L+LSGCL+CYL S + L++P P +C IQR+ +GLGFA+MYASLLTKTNR+ARIF++A++TAKRP  ISP+SQL I   LI +Q   +AIWL F PP  R D  +  F VL+C I+  + + SL Y MLLI VCT YA+KTR IPENFNESKFIGF MYTTC+IWLAF+ IYF T+ +FE+Q+STL ++VSLSA VTL+CLF PKL+II+ QPEKNVRKLTM+S T  K
Sbjct:   44 ATVPGDIILGGLFPVHSSGALKCQSLNPERGIQRVEAMLFTLDEINNNPNLLPGLRLGANIRDTCSLGNHALEQSLDFVKTTVTDVTSRPQETHTSTDCPCASSQLSASNRMTATHARPASWSQNIVRGVVGGSYSTVSILVANLYRLFQLPQISYASTSAVLSDKRTYPLFARTVPSDVEQARAMADLVAAHNWTYVSTVRSAGDYGDSGMDAFWKEADKRGVCIAAREVIRGSSTKRDLDEVVKVLRYGFSKARVVVLFTRMDHTKLLLNAVRRANLTDHFVWIASDGWGRENVPVENNSRVANGALTIEILAEEIGQFSVYYKNLRSD-NTRNPWFSKYWESLFGCT-----------------------YDNSSNTAESDGNSSNDGDSKNRMPSCLSNPKNR-------LGDKLPLPFKQEAKIQFVYDAIYAFAWGLHKLQQSLC-PFNPDPAKWDKDECIRKLLSHKGKDFYDLIIKTSFKDNYGNLVAFDENGDGVGQYLIYNYARDPYTGEYNYRLVGDYQKSKLSMRSRPIWPGGQSRLVPSSQCSEECPFGSVRQYSKKQQCCWTCEECQANQIIINLTTCETCPDQYWPTANRTICERLKLHYIKPNSWFAIIPMILNCIGILATIGVIVTLALYSETPIVRATGRELTYLLLSGCLLCYLSSLLLLIEPNPAACGIQRVGIGLGFAIMYASLLTKTNRLARIFDAAKRTAKRPAFISPRSQLAIAGGLIGLQFALSAIWLGFDPPATRIDPIQSNFLVLRCAIKDSSLMTSLAYIMLLIVVCTIYAVKTRCIPENFNESKFIGFAMYTTCIIWLAFVPIYFATMSNFEIQVSTLSVAVSLSATVTLVCLFAPKLYIIYFQPEKNVRKLTMNSGTGNK 901          
BLAST of Metabotropic glutamate receptor vs. TrEMBL
Match: A0A5K4F494 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 903.279 bits (2333), Expect = 0.000e+0
Identity = 452/899 (50.28%), Postives = 618/899 (68.74%), Query Frame = 2
Query:   95 LPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDC--IPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCK------PFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRK 2764
            L I++++     +N +  + D    ++I  GDI+LGGLFPVH S    C+ INP+RGIQR+EAMLFT+ EINN   +LP + +G  I DTCS   +AL+Q+L F+++S   ++  +     + SE L         R VVG SYSSV+ILVANL RLFS+PQISYAST+A+LS+K+  P+FART+PSD  QA+AMA LV++ NWTYVSTVRS+GDYGDSG+DAFWKE+ KLGVCIAA+E+I+ N    DL  IV  L ++F+K RVVVLFT +DHTKLLL+AV+     N+F+WIASDGWG+EN PV+NNS  ANGA+T E++   IK FT Y+  L    N  NPWF EYW++L  C     K++ R S SS +  MS         TN  + ++ +  S         S ++K R  L           +FKQE+KIQ VYDAVYA A  L   Q KLC        +    C++ + +  G  FY+ +IN SFTD+YGN V+FD NGD  GQY+IYNY R+  TG+Y+Y+ +G+F+   L + +   WPG E K+ P S CSE+C  G++R   K+ +CCW C  C  ++ VVN+T CE C    WP +++  C LL +HY+ +S W AI+P+  S LG   T  V+  + +Y +TP++RA+GREL+++ L+GCLVCY  +F+ + +P+ ++C++QRIL+GLGFA+MYASLLTKTNRIARIF++A++T KRP  ISP+SQL I   LI++QL  +AIW  F  P  R D  +P + VL+C ++ K+FL+SL YNM+LI VCT YA+KTR+IPENFNESKFIGFTMYTTC+IWLAF+ +Y+ T+ + ++QI+TL IS++LSA V L CLFFPKL+II+L+PEKNVR+LTM++ T ++
Sbjct:   10 LMIILWFHLVTIINCLQRKYDKNTVASI-PGDIMLGGLFPVHTSGVTTCESINPERGIQRVEAMLFTLDEINNNSKLLPGLTLGTTIRDTCSDTNHALEQALKFVQASTGSSSQLNKM--NEHSENL-------NTRGVVGSSYSSVTILVANLFRLFSLPQISYASTTAILSDKRAFPLFARTVPSDVVQAQAMATLVSAHNWTYVSTVRSAGDYGDSGMDAFWKEADKLGVCIAAREVIRGNTGPEDLDNIVNVLSKDFAKARVVVLFTGMDHTKLLLDAVRRAGLVNHFVWIASDGWGRENVPVSNNSREANGALTIEIQAEPIKAFTDYYLSLG-RENHRNPWFREYWQDLLQCRESSTKRRERKSTSSRRYFMSKLSKN---ETNLENSHEISTESSSLPSSCSDSPNLKLRDILG---------PDFKQEAKIQFVYDAVYAFASGLHILQKKLCPGNPHHPKWNKRSCLEKMLSYPGTAFYQLIINTSFTDNYGNYVAFDENGDGYGQYSIYNYARDPYTGQYHYRLVGDFQGGKLTMRARPIWPGGESKKFPVSQCSEECGFGEVRRLDKKQQCCWSCETCGVDQRVVNLTHCETCPFQHWPSKDKRTCELLELHYIDISTWFAIVPITFSSLGILITGGVILTWVFYSDTPLIRATGRELAYVQLAGCLVCYSCAFILIARPSIFTCSLQRILIGLGFAMMYASLLTKTNRIARIFDAAKRTTKRPVYISPRSQLAISGSLIALQLSLSAIWFGFDSPDTRIDEIRPGYLVLRCAMKDKSFLISLAYNMILIIVCTAYAVKTRQIPENFNESKFIGFTMYTTCIIWLAFLPMYYATISNHQIQIATLCISINLSASVMLCCLFFPKLYIIYLRPEKNVRRLTMNNMTAKQ 885          
BLAST of Metabotropic glutamate receptor vs. TrEMBL
Match: A0A5K4F3Y9 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 903.279 bits (2333), Expect = 0.000e+0
Identity = 452/899 (50.28%), Postives = 618/899 (68.74%), Query Frame = 2
Query:   95 LPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDC--IPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCK------PFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRK 2764
            L I++++     +N +  + D    ++I  GDI+LGGLFPVH S    C+ INP+RGIQR+EAMLFT+ EINN   +LP + +G  I DTCS   +AL+Q+L F+++S   ++  +     + SE L         R VVG SYSSV+ILVANL RLFS+PQISYAST+A+LS+K+  P+FART+PSD  QA+AMA LV++ NWTYVSTVRS+GDYGDSG+DAFWKE+ KLGVCIAA+E+I+ N    DL  IV  L ++F+K RVVVLFT +DHTKLLL+AV+     N+F+WIASDGWG+EN PV+NNS  ANGA+T E++   IK FT Y+  L    N  NPWF EYW++L  C     K++ R S SS +  MS         TN  + ++ +  S         S ++K R  L           +FKQE+KIQ VYDAVYA A  L   Q KLC        +    C++ + +  G  FY+ +IN SFTD+YGN V+FD NGD  GQY+IYNY R+  TG+Y+Y+ +G+F+   L + +   WPG E K+ P S CSE+C  G++R   K+ +CCW C  C  ++ VVN+T CE C    WP +++  C LL +HY+ +S W AI+P+  S LG   T  V+  + +Y +TP++RA+GREL+++ L+GCLVCY  +F+ + +P+ ++C++QRIL+GLGFA+MYASLLTKTNRIARIF++A++T KRP  ISP+SQL I   LI++QL  +AIW  F  P  R D  +P + VL+C ++ K+FL+SL YNM+LI VCT YA+KTR+IPENFNESKFIGFTMYTTC+IWLAF+ +Y+ T+ + ++QI+TL IS++LSA V L CLFFPKL+II+L+PEKNVR+LTM++ T ++
Sbjct:   10 LMIILWFHLVTIINCLQRKYDKNTVASI-PGDIMLGGLFPVHTSGVTTCESINPERGIQRVEAMLFTLDEINNNSKLLPGLTLGTTIRDTCSDTNHALEQALKFVQASTGSSSQLNKM--NEHSENL-------NTRGVVGSSYSSVTILVANLFRLFSLPQISYASTTAILSDKRAFPLFARTVPSDVVQAQAMATLVSAHNWTYVSTVRSAGDYGDSGMDAFWKEADKLGVCIAAREVIRGNTGPEDLDNIVNVLSKDFAKARVVVLFTGMDHTKLLLDAVRRAGLVNHFVWIASDGWGRENVPVSNNSREANGALTIEIQAEPIKAFTDYYLSLG-RENHRNPWFREYWQDLLQCRESSTKRRERKSTSSRRYFMSKLSKN---ETNLENSHEISTESSSLPSSCSDSPNLKLRDILG---------PDFKQEAKIQFVYDAVYAFASGLHILQKKLCPGNPHHPKWNKRSCLEKMLSYPGTAFYQLIINTSFTDNYGNYVAFDENGDGYGQYSIYNYARDPYTGQYHYRLVGDFQGGKLTMRARPIWPGGESKKFPVSQCSEECGFGEVRRLDKKQQCCWSCETCGVDQRVVNLTHCETCPFQHWPSKDKRTCELLELHYIDISTWFAIVPITFSSLGILITGGVILTWVFYSDTPLIRATGRELAYVQLAGCLVCYSCAFILIARPSIFTCSLQRILIGLGFAMMYASLLTKTNRIARIFDAAKRTTKRPVYISPRSQLAISGSLIALQLSLSAIWFGFDSPDTRIDEIRPGYLVLRCAMKDKSFLISLAYNMILIIVCTAYAVKTRQIPENFNESKFIGFTMYTTCIIWLAFLPMYYATISNHQIQIATLCISINLSASVMLCCLFFPKLYIIYLRPEKNVRRLTMNNMTAKQ 885          
BLAST of Metabotropic glutamate receptor vs. TrEMBL
Match: A0A158RER6 (G_PROTEIN_RECEP_F3_4 domain-containing protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS7877 PE=3 SV=1)

HSP 1 Score: 893.649 bits (2308), Expect = 0.000e+0
Identity = 459/890 (51.57%), Postives = 603/890 (67.75%), Query Frame = 2
Query:  173 AIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSD-NNDASDY--------------YC-----KDKSEVLRH-TKATQKI-RTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKL-KNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLE-------KCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSS 2749
            A   GDIILGGLFPVH S    C  +NP+RGIQRLE MLFT+ EINN   +LP + +GA + DTCS   +AL+QSLDF+K+++ D  N+  +               YC     +  S  + H T  +Q I R VVGGSY++VSILVANL RLF +PQISYASTSA+LS+K+ +P+FART+PSD +QA+ MA LVA+ NWTYVSTVRS+GDYGDSG+DAFWKE+ K  VCIAA+E+++ +   SDL  +V+ L   FSK RVVVLFTR+DHTKLLL+AV+  N++++F++I SDGWG+EN PV NNS VANGA+T E+   EI+ F+TY+  L  + N+ NPWF +YW+ LF C                              F + + Q QN  H +        V   K+L        KL + FKQE+KIQ VYDAVYA+A+ L   Q KLC PF  +       +C++ L    G  FYK +I+ +F D+Y NLV+FD NGD VGQY IYNY R+  +G+Y Y+ +G++++  L +     WPG + K +P S CSE+CP G +R YSK+ +CCW C  C+ N+ + N+T C+ CA+  WP  +R  C LL +HY+K+S W AI PM+L+F+G   T  V+     Y  TPIVRA+GREL++L+LSGCL+CYL S + L+ P P +CAIQR+ +GLGFA+MYASLLTKTNR+ARIF++A++T KRP  ISP+SQL I   L+ +Q   + IWL F PP  R D  +P F VL+C I+  + + SL Y MLLI VCT YA+KTR IPENFNES+FIGF MYTTC+IWLAF+ IYF T+ SFE+QISTL +SVSLSA VTL+CLF PK++II+  PEKN+RKLTM+S
Sbjct:   48 ATVPGDIILGGLFPVHSSGAVKCMSLNPERGIQRLEGMLFTLDEINNNSALLPGLRLGANLRDTCSLGNHALEQSLDFVKTTVDDVMNEPKEQDKMCVCPCAPGGIPYCPGGGQRMSSSTMPHPTSWSQDIVRGVVGGSYTTVSILVANLYRLFKLPQISYASTSAVLSDKRTYPLFARTVPSDVEQARVMAALVAAHNWTYVSTVRSAGDYGDSGMDAFWKEADKRDVCIAAREVVRGSSSSSDLDEVVRVLRYGFSKARVVVLFTRMDHTKLLLDAVRRANHTDHFVFIGSDGWGRENMPVLNNSRVANGALTIEILATEIEKFSTYYKNLRLD-NTRNPWFAKYWQSLFGC-----------------------------TFDNSSTQ-QNVPHCE--------VTKNKRL------GDKLPEPFKQEAKIQFVYDAVYALAHGLHNLQQKLC-PFDPDPAKWDKNECIRKLLAYPGDEFYKIIISTTFKDNYNNLVAFDENGDGVGQYLIYNYARDLYSGEYQYRLVGDYKNSKLSMRYRPIWPGGQSKLVPSSQCSEECPFGSVRKYSKKQQCCWTCEECQPNQIIANLTHCQTCADQYWPTLDRRTCELLELHYIKVSSWFAIFPMVLNFIGIVATVGVIVTLALYSETPIVRATGRELTYLLLSGCLLCYLSSLILLVPPNPAACAIQRVGIGLGFAIMYASLLTKTNRLARIFDAAKRTTKRPAFISPRSQLAIAGGLVGLQFALSVIWLGFDPPSTRVDPLQPNFLVLRCAIKDSSMVTSLAYIMLLIVVCTIYAVKTRSIPENFNESRFIGFAMYTTCIIWLAFVPIYFATMSSFEIQISTLSVSVSLSATVTLVCLFAPKVYIIYFHPEKNIRKLTMNS 891          
BLAST of Metabotropic glutamate receptor vs. TrEMBL
Match: A0A4E0RXQ7 (Metabotropic glutamate receptor OS=Fasciola hepatica OX=6192 GN=D915_002413 PE=3 SV=1)

HSP 1 Score: 886.33 bits (2289), Expect = 0.000e+0
Identity = 452/905 (49.94%), Postives = 597/905 (65.97%), Query Frame = 2
Query:  119 FFVTVNLIASEIDNKYQSAIYN------GDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKS-SLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC--KPFVLE----KCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPG-EEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTV----------------HYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTM 2743
            FF+ + L   E+    +SA         GDI+LGGLFPVH S   +C  INP+RGIQR+EAMLFTI EINN+ ++LP I +GA I DTCS   + L+Q+L F++S S  DN + +    +  S V+         R VVG SYSSV+ILVANL RLFSIPQISYASTSA+LS+K+  P+FART+PSD  QA+AMA LV++ NWTYVSTVRS+GDYGDSG+DAFWKE+ KLGVCIAA+E+I+PN    +L AIV  L  +F+K RVVVLFT +DHTKLLL+AV+    +++F+WIASDGWG+EN PV+NNS VANGA+T E+++  +  FT ++  L Y+ N  NPWF EYWE+LF C      +R  R++   +           T     +K  +    RD   P                      +FKQE+KIQ VYDAVYA A  L   Q +LC   P         CV  L N  G+ FYK +I  +FT ++GN+V+FD NGD  GQY+IYNY R+  TG Y Y+ +G+++   L + +   WPG +   +P S CSE+C   +IR   K+ +CCW C  C  ++ VVN+T CE CA   WP  NRT C LL V                HY+ LS W  I+PM +S +G   T  ++  +  Y  TP+VRA+GREL+++ LSGCLVCY   FV L  P+ ++C++QRIL+GLGFA+MYASLLTKTNRIARIFE+A++T +RP  ISP+SQL+I   LI++QL  +AIW  F PP  R D   P + VL+C ++ K+ L+SL YNM+LI VCT +A+KTR IPENFNESKFIGF MYTTC+IWLAF+ +++ T+++ ++QI+TL IS++LSA V L CLF PKL+II++ PEKNVR+LTM
Sbjct:   23 FFLIMCLTRLELSKGSKSAGKQLIAEVPGDIMLGGLFPVHTSGATMCNAINPERGIQRVEAMLFTIDEINNKSELLPGIRLGATIRDTCSASNFGLEQALQFVQSGSKCDNVNWAQQPQQPSSNVV--------TRGVVGSSYSSVTILVANLFRLFSIPQISYASTSAVLSDKRAFPLFARTVPSDVVQARAMASLVSAHNWTYVSTVRSAGDYGDSGMDAFWKEADKLGVCIAAREVIRPNYGTDELDAIVHVLRYDFAKARVVVLFTGMDHTKLLLDAVRRAGLTDHFVWIASDGWGRENLPVSNNSRVANGALTIEIQSKPVAAFTDHYLNLGYD-NPRNPWFKEYWEDLFGCT-FGNSVRRKRATTDKVK--------MVTALVPCSKDPKLRL-RDKIGP----------------------DFKQEAKIQFVYDAVYAFASGLHMLQRQLCLGSPHSPNWDKYGCVAKLLNYSGVDFYKLMIKANFTPTHGNMVAFDDNGDGNGQYSIYNYARDPYTGHYDYRLVGDYQGGKLTMRARPIWPGGQSSRLPVSQCSEECGFAEIRRLDKKQQCCWSCEACGPDQRVVNLTHCETCAFQHWPSANRTTCELLEVRAALLSFLFILLITHLHYIDLSTWFGIVPMTISSVGIVLTIGIIVTWLVYSETPVVRATGRELAYVQLSGCLVCYACPFVLLSTPSVFTCSLQRILIGLGFAMMYASLLTKTNRIARIFEAAKRTTRRPVYISPRSQLVITGSLITLQLAVSAIWFGFDPPDTRIDPVGPSYLVLRCAMKDKSLLISLAYNMILIVVCTAHAVKTRHIPENFNESKFIGFAMYTTCIIWLAFLPMFYATMNNHQIQITTLCISIALSASVMLSCLFLPKLYIIYIHPEKNVRRLTM 886          
BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Match: grm2a (metabotropic glutamate receptor 2 [Source:NCBI gene;Acc:103035135])

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 382/896 (42.63%), Postives = 525/896 (58.59%), Query Frame = 2
Query:  155 DNKYQSAIYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMN 2809
            D+  +     GD+++GGLFPVH      E C +IN  RGIQRLEAML  + +IN    ILP + +GA ILDTCSKDTYAL+QSL+F+++SL+  +D ++Y C D S  + H      I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKA+AE++  FNWTYVSTV S GDYG++GIDAF +E++ L +CIA    + +   LHS    ++++L Q+ S  +VV+LFTR +  + LL A K MN S  F+W+ASDGWG +   V  + +VA+GA T E+ +  I  F  YF  L    N+ NPWF E+WE  F C            S+  +  GK S                    RD +F                         + ESKI  V +AVYA+A+ +   +  +C      K   A+   +G  FYKD I     D+        N V FD+ GDS+G+YNI++Y  +K+   Y Y+ +G +        S + W   ++ +P S CS+ C   +I+       CCW C  C+  +Y+++   C  C+ G+WP  N TGCY L   Y+      AI P+ ++ LG   T  V+G+F     TP+V+ASGRELS+++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ ICA LIS QLL   +WL    PG+R +   ++ +   LKC  +  + L+SL YN +LI +CT+YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L +++T +   T    SF+     N
Sbjct:   41 DSTKKEIAIEGDLVIGGLFPVHQKGEGVEDCGRINAQRGIQRLEAMLLALDKINEDDSILPGVTLGAHILDTCSKDTYALEQSLEFVRASLTKVDD-NEYTCPDGSYAI-HDDTPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAIAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARALQICIATSAKVSRSMDLHS-YDQVIRSLLQK-SNAKVVILFTRSEDARELLVAAKRMNVS--FIWVASDGWGAQESVVRGSESVADGAFTIELASYPIPEFADYFLGLNPYNNTRNPWFREFWENHFQC------------SLHDIHCGKHSL-------------------RDGKF-------------------------EPESKIMFVVNAVYAMAHAMHNMRQAVC--LNTTKICSAMKPPNGKKFYKDYILKLKFDAPFRPADTENTVHFDAYGDSLGRYNIFHY--HKEDDGYVYRKVGYWAQTLDLNTSLIPW---DQMVPTSQCSDPCRKNEIKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPNANLTGCYNLPEEYIHWEDAWAIGPVTIACLGILCTLFVIGLFLKNNETPVVKASGRELSYILLLGVLLCYCITFIYITKPSAVVCTLRRLGLGTSFAVCYSALLTKTNRIARIFNGVKDGAQRPRFISPASQVAICAALISFQLLVVVVWLLVEAPGVRKEVSPERRDIVRLKCNSKDSSMLMSLTYNCILIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTTLRVATTRFSVTTGPGSSFSQASAAN 867          
BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Match: grm3 (metabotropic glutamate receptor 3 [Source:NCBI gene;Acc:103035018])

HSP 1 Score: 667.922 bits (1722), Expect = 0.000e+0
Identity = 380/908 (41.85%), Postives = 541/908 (59.58%), Query Frame = 2
Query:  146 SEIDNKYQSAIYNGDIILGGLFPVHDSETEL--CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNS-EVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV--RKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            S  D+  +    +GD++LGGLFP+H+    +  C +IN DRGIQRLEAMLF I +IN    +LP + +G  ILDTCS+DTYAL+Q+L+F+++SL+  +D +++ C D S   +   +   I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++ +FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E + + N   S   A+V+ L Q+    RVVVLF R D  + LL A   +N S  FLW+ASDGWG +   V  +   A+GAIT E+    I +F  YF  L    N  NPW+ ++WE+ F C            S+   +S                               S  + + K  C     +    NF+ ESKI  V +AV+A+A+ L R Q  LC      +   A+ ++DG   Y+D L++ +F   +      N+V FD  GD +G+YNI+NY R   + K+ Y  +GE+  + L LN   + WP     +P S CS+ C   +++       CCW C+ C+  EY+ +   C  CA G+WP  + +GCY L   Y+      AI P+ ++ +G   T+ V  VF  + +TP+V+ASGREL +++L G L+ Y ++F+F+ KP+P  CA++R+ LG  FAV Y++LLTKTNRIARIF   +   A+RP  ISP SQ+ IC   ISVQLL  ++WL    PG R     +K +  +LKC +   + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV   +L ++  +   P     ++A+H  +++ Y P
Sbjct:   20 SSGDSPRREIKIDGDLVLGGLFPIHEKGLGMDECGRINEDRGIQRLEAMLFAIDQINRDVSLLPGVVLGVHILDTCSRDTYALEQALEFVRASLTKVDD-TEFICPDGSYAFQE-DSPLAIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRAFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATSEKVGRSNAKRSSYEAVVRQLLQK-PTARVVVLFLRSDDARELLGAATRLNAS--FLWVASDGWGAQESIVKGSEFAADGAITLELAAHPIPDFNQYFQSLNPRNNHRNPWYRDFWEQKFQC------------SLGGTLS-------------------------------STGMGTPKPPCDQ-GLAVDDSNFEPESKIMFVVNAVFAMAHALHRMQRALCAN--TTRLCDAMRSLDGRRLYRDFLLHINFRAPFSPPGSENVVKFDQYGDGLGRYNIFNYQRLPGSDKFTYIQVGEW-AETLSLNEFLIGWP-RGGGLPTSQCSDPCAPNEMKKMQAGEYCCWICTACEPYEYLPDEFTCAPCALGQWPRDDLSGCYDLPEDYIMWEDAWAIGPISIACVGFVCTSLVFTVFIRHNDTPLVKASGRELCYILLLGVLMSYSMTFIFIAKPSPAVCALRRLGLGTSFAVCYSALLTKTNRIARIFSGVKDGGAQRPRFISPSSQVFICLSFISVQLLLVSVWLLLEVPGTRRFTLPEKRQTVILKCNVRDSSMLLSLSYDVVLVVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNLNRFSVSGPAT---TYASHASVSAHYVP 871          
BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Match: grm2b (metabotropic glutamate receptor 2-like [Source:NCBI gene;Acc:103030591])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 385/902 (42.68%), Postives = 532/902 (58.98%), Query Frame = 2
Query:  176 IYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL-----------TMSSTTYRKPTNSSG---SFANHREM 2806
            + +GD+++GGLFPVH+    T+ C KIN  RGIQRLEAML  + EIN    ILP   +GA ILDTCSKDTYAL+QSL+F+++SL+  +    + C D S  +   +A   I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +    +   ++++L Q+ +  +VV+LFTR +  + LL A   MN +  F+W+ASDGWG +   V  +   ANGA T E+ +  I+ F  YF +LT   N+ NPWF E+WE  F C     ++     +  SL                                R  S K   ++  + N               +VY   +A    L   +  +C P     C +A+   +G  FY++ I  +  D+        N+V F S GDS+G+YNI++Y   ++ G+Y YK +G +   GL LN+  V WPG    IP S CS+ C   + +       CCW C  C++++++++   CE C  GEWP  N TGCY L   Y+  S   A+ P+ ++ LG   T +V GVF    +TP+V+ASGRELS+++L G L+CY ++F+++ KP+   CA++R+ LG  FAV Y++LLTKTNRIARIF  A+ +A+RP  ISP SQ+ ICAVLIS QLL   +WL    PG+R +   ++ +   LKC     + LVSL YN +LI +CT+YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L           T  S+TY + T+S+    +  N RE+
Sbjct:   24 VMDGDLVIGGLFPVHEKGEGTQDCGKINEQRGIQRLEAMLLALDEINQDNRILPGFRLGAHILDTCSKDTYALEQSLEFVRASLTKVHQPG-FICPDGSNPVPD-EAPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARVRQICIATSVKVSRSMNRVNYETVIRSLQQK-ANAKVVILFTRSEDARELLVAAARMNVT--FIWVASDGWGAQESVVHGSEKAANGAFTIELASYSIREFEDYFTKLTPELNTRNPWFREFWEHKFGC-----RLHEPGCASHSL--------------------------------RDGSFKQESKIMFVMN---------------AVYAMAHA----LHNMRQAVC-PNTTRVC-EAMKPGNGKRFYREFILKTKFDAPFRPAETENVVRFTSLGDSLGRYNIFHY--GQENGRYVYKKVG-YWSQGLVLNTSLVPWPG--GAIPTSQCSDPCQPNEAKSMQPGDVCCWICIPCQAHQFLLDEFTCEDCGFGEWPLTNLTGCYELPEEYIHWSDAWAVGPVTIACLGMLCTMAVAGVFLRNNDTPVVKASGRELSYILLFGVLLCYAMTFIYIAKPSAVVCALRRLGLGTSFAVCYSALLTKTNRIARIFGGARDSAQRPRFISPASQMAICAVLISAQLLVALVWLLVEAPGVRKELSPERRDVVTLKCNSLDSSMLVSLTYNCILIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTSLRKNDNRFSTAITAPSSTYSQGTSSATVVPTVCNGREV 857          
BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Match: grm2b (metabotropic glutamate receptor 2-like [Source:NCBI gene;Acc:103030591])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 392/939 (41.75%), Postives = 546/939 (58.15%), Query Frame = 2
Query:   86 CNQLPIVIYYSFFVTVNLIASEIDNKYQSA--------IYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDS------YGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKL-----------TMSSTTYRKPTNSS--GSFANHREM 2806
            C  LP+V     F+ + L  ++   +Y  A        + +GD+++GGLFPVH+    T+ C KIN  RGIQRLEAML  + EIN    ILP   +GA ILDTCSKDTYAL+QSL+F+++SL+  +    + C D S  +   +A   I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +    +   ++++L Q+ +  +VV+LFTR +  + LL A   MN +  F+W+ASDGWG +   V  +   ANGA T E+ +  I+ F  YF +LT   N+ NPWF E+WE  F C     ++     +  SL                                R  S K   ++  + N               +VY   +A    L   +  +C P     C +A+   +G  FY++ I  +  D+        N+V F S GDS+G+YNI++Y   ++ G+Y YK +G +   GL LN S V WPG    IP S CS+ C   + +       CCW C  C++++++++   CE C  GEWP  N TGCY L   Y+  S   A+ P+ ++ LG   T +V GVF    +TP+V+ASGRELS+++L G L+CY ++F+++ KP+   CA++R+ LG  FAV Y++LLTKTNRIARIF  A+ +A+RP  ISP SQ+ ICAVLIS QLL   +WL    PG+R +   ++ +   LKC     + LVSL YN +LI +CT+YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L           T  S+TY + ++++   +  N RE+
Sbjct:   15 CPWLPLVA----FLLLMLPQAQTSPRYLPALPGTKREIVMDGDLVIGGLFPVHEKGEGTQDCGKINEQRGIQRLEAMLLALDEINQDNRILPGFRLGAHILDTCSKDTYALEQSLEFVRASLTKVHQPG-FICPDGSNPVPD-EAPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARVRQICIATSVKVSRSMNRVNYETVIRSLQQK-ANAKVVILFTRSEDARELLVAAARMNVT--FIWVASDGWGAQESVVHGSEKAANGAFTIELASYSIREFEDYFTKLTPELNTRNPWFREFWEHKFGC-----RLHEPGCASHSL--------------------------------RDGSFKQESKIMFVMN---------------AVYAMAHA----LHNMRQAVC-PNTTRVC-EAMKPGNGKRFYREFILKTKFDAPFRPAETENVVRFTSLGDSLGRYNIFHY--GQENGRYVYKKVG-YWSQGLVLNTSLVPWPG--GAIPTSQCSDPCQPNEAKSMQPGDVCCWICIPCQAHQFLLDEFTCEDCGFGEWPLTNLTGCYELPEEYIHWSDAWAVGPVTIACLGMLCTMAVAGVFLRNNDTPVVKASGRELSYILLFGVLLCYAMTFIYIAKPSAVVCALRRLGLGTSFAVCYSALLTKTNRIARIFGGARDSAQRPRFISPASQMAICAVLISAQLLVALVWLLVEAPGVRKELSPERRDVVTLKCNSLDSSMLVSLTYNCILIILCTFYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVTSLRKNDNRFSTAITAPSSTYSQASSATVVPTVCNGREV 881          
BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Match: grm3 (metabotropic glutamate receptor 3 [Source:NCBI gene;Acc:103035018])

HSP 1 Score: 639.032 bits (1647), Expect = 0.000e+0
Identity = 373/908 (41.08%), Postives = 538/908 (59.25%), Query Frame = 2
Query:  146 SEIDNKYQSAIYNGDIILGGLFPVHDSETEL--CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI-KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNS-EVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNV--RKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            S  D+  +    +GD++LGGLFP+H+    +  C +IN DRGIQRLEAMLF I +IN    +LP + +G  ILDTCS+DTYAL+Q+L+F+++SL+  +D +++ C D S   +   +   I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++ +FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E + + N   S   A+V+ L Q+    RVVVLF R D  + LL A   +N S  FLW+ASDGWG +   V  +   A+GAIT E+    I                  P F++Y++ L                                   +    ++N ++RD+          +K  C++ + S    NF+ ESKI  V +AV+A+A+ L R Q  LC      +   A+ ++DG   Y+D L++ +F   +      N+V FD  GD +G+YNI+NY R   + K+ Y  +GE+  + L LN   + WP     +P S CS+ C   +++       CCW C+ C+  EY+ +   C  CA G+WP  + +GCY L   Y+      AI P+ ++ +G   T+ V  VF  + +TP+V+ASGREL +++L G L+ Y ++F+F+ KP+P  CA++R+ LG  FAV Y++LLTKTNRIARIF   +   A+RP  ISP SQ+ IC   ISVQLL  ++WL    PG R     +K +  +LKC +   + L+SL Y+++L+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV   +L ++  +   P     ++A+H  +++ Y P
Sbjct:   20 SSGDSPRREIKIDGDLVLGGLFPIHEKGLGMDECGRINEDRGIQRLEAMLFAIDQINRDVSLLPGVVLGVHILDTCSRDTYALEQALEFVRASLTKVDD-TEFICPDGSYAFQE-DSPLAIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMAEILRAFNWTYVSTVASEGDYGETGIEAFEQEARLRNICIATSEKVGRSNAKRSSYEAVVRQLLQK-PTARVVVLFLRSDDARELLGAATRLNAS--FLWVASDGWGAQESIVKGSEFAADGAITLELAAHPI------------------PDFNQYFQSL-----------------------------------NPRNNHRNPWYRDF--------WEQKFQCSLVDDS----NFEPESKIMFVVNAVFAMAHALHRMQRALCAN--TTRLCDAMRSLDGRRLYRDFLLHINFRAPFSPPGSENVVKFDQYGDGLGRYNIFNYQRLPGSDKFTYIQVGEW-AETLSLNEFLIGWP-RGGGLPTSQCSDPCAPNEMKKMQAGEYCCWICTACEPYEYLPDEFTCAPCALGQWPRDDLSGCYDLPEDYIMWEDAWAIGPISIACVGFVCTSLVFTVFIRHNDTPLVKASGRELCYILLLGVLMSYSMTFIFIAKPSPAVCALRRLGLGTSFAVCYSALLTKTNRIARIFSGVKDGGAQRPRFISPSSQVFICLSFISVQLLLVSVWLLLEVPGTRRFTLPEKRQTVILKCNVRDSSMLLSLSYDVVLVVLCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNLNRFSVSGPAT---TYASHASVSAHYVP 850          
BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Match: grm3 (glutamate receptor, metabotropic 3 [Source:ZFIN;Acc:ZDB-GENE-061009-13])

HSP 1 Score: 648.662 bits (1672), Expect = 0.000e+0
Identity = 375/907 (41.35%), Postives = 525/907 (57.88%), Query Frame = 2
Query:  131 VNLIASEIDNKYQSAIYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLI-NNSFTDSYGN---LVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK-TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
            V L  +E  +  +    +GD++LGGLFPVH+  S  E C KIN DRGIQRLEAMLF + +IN    +LP I +GA ILDTCS+DTYAL+QSL+F++SSL    D ++Y C D S  +++   T  I  V+GGSYSSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  F WTYVSTV S  DYG++G++AF  E +   +CIA  E +  +        ++K L Q+    +VVVLFTR D  K LL A ++++ S  F W+ASDGWG     +    +VA+GA+T E+ +  +K F  YF  L   +N  NPWF E+W++ F C        +SR              + H N  + +                               S +  ++KQE+KI  V DAV+A+A+ L     +LC P   + C  A   I+G+  YK+ I N SF   +G+   +V FDS+GD + +YNI+  I  K  GKY Y  +G +    +   +E+ W   +  IP S CS+ C   +++   +   CCW C  C+  EY+ +   C  C  G WP  +   CY L   Y+K     A++P+ +S +G   T +V+  F  + NTPIV+ASGREL + +L+G  +CY  +F F+ K T   CA++R++L   F V Y++LLTKTNRI+R+F SA++  + RP  +SP +Q++IC  LI +QL   AIWL    PG+R      K E  +LKC ++    L+SLV N+ L+ VCT YA K RK  ++FNE+KFI FTMYTTC+IWLAF+ I++ T   + VQ +T+ +SVSLS  V L CLF PK++II  QP KNV +     TT      ++ SF+     N+ Y P
Sbjct:   16 VALTQNEGGSGKREVRMDGDLVLGGLFPVHEKGSGPEDCGKINEDRGIQRLEAMLFALGQINRDSSLLPGIKLGAHILDTCSRDTYALEQSLEFVRSSLL-KVDETEYMCPDGSYAIQNQGPT-AIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDFFARTVPPDFYQAKAMAEILRFFKWTYVSTVASDDDYGEAGMEAFEHEVRSRNICIAVSEKVGRSANKKTYDGVIKALMQK-PNAKVVVLFTRSDDAKELLAAARMLHAS--FYWVASDGWGALESVIKGQEDVADGALTIELNSQRVKEFDDYFQSLLPAKNKRNPWFTEFWQQRFQCT-------LSRG-------------HRHGNVCNAS------------------------------MSLRRGSYKQETKIMFVIDAVFALAHALHNMHKELC-PNTTKLCA-AFTPINGVKLYKEFILNVSFQAPFGDHDRIVKFDSSGDGLAKYNIF--IFQKSNGKYSYTKVGHWSQGLVLQANEIHW--AKSSIPVSQCSDPCAPNEMKSTQRGDSCCWVCISCQPYEYLYDEFTCMDCGPGRWPSADLRDCYDLPEEYIKWEDAWALVPIAISCIGLICTVTVLITFIVHGNTPIVKASGRELCYALLAGVSMCYSTTFAFVAKATVLVCALRRLVLAASFVVCYSALLTKTNRISRMFNSAREGGSSRPKFVSPLAQMVICLTLILIQLSVVAIWLIVENPGLRRFTIPDKREVVILKCSVQDSNMLISLVCNVCLVMVCTVYAFKNRKCHDSFNEAKFIAFTMYTTCIIWLAFVPIFYVTSGDYRVQTTTICVSVSLSGSVVLGCLFAPKVNIILFQPHKNVER-PPKPTTISLAAGTATSFS-LPSANAPYVP 859          
BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007590.1 (pep scaffold:Pmarinus_7.0:GL478498:6932:63706:-1 gene:ENSPMAG00000006812.1 transcript:ENSPMAT00000007590.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0
Identity = 324/827 (39.18%), Postives = 459/827 (55.50%), Query Frame = 2
Query:  182 NGDIILGGLFPVH--DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLG-----VCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNY-IRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPG--IRYDRKKPEFP-----VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFE 2617
            +GDI LG LFPVH       +C  +  ++GI RLEAML+ +  IN  P ILPN+ +GAR+LDTCS+DTYAL+QSL F+++ +    D +D  C + ++ +      +K+  V+G + SSVSI+VAN+LRLF IPQISYAST+  LS+   +  F+R +P D  QA+AM E+V++  W YVSTV ++ +YG+SGI+ F + ++  G     VCIA    I   P  SD   I+  L  E    R ++LF   D  K LL A +  N + +FLW+ASD WG +  P+ N  + A GAIT   K   +  F  YF   T   N  N WF E+WEE F C       R+SR   +  +  K+                                      CT      +   ++QE K+Q V DAVYA+A+ L     K C P +   CV  +  +      +++ + SF  S G  V F+ +GD+ G+Y+I+ Y + N  T  Y    IGE+ +      S + W    +E+P SICS  C  G+ +   K   CCW C  C+   + ++   C +C     P  NRTGC  + +  ++     A++P+ L+ LG  TT  V+  F  Y +TPIVRASGRELS+++L+G  +CY  +F+ + +P+   C+ +RI LGLG  V YA+LLTKTNRI RIFE  +++   P  ISP SQL+I   LI+VQLL   IW   +PP   I Y+ ++ +       +LKC I     + SL Y++LL+  CT YAIKTR +PENFNE+K IGFTMYTTC++WLAFI I+FGT  S E
Sbjct:   42 DGDITLGALFPVHARGDRGAMCGALKMEKGIHRLEAMLYALDTINADPRILPNVTLGARVLDTCSRDTYALEQSLTFVQALI--EKDTADVRCTNNAQPI--FAKPEKVVGVIGAAGSSVSIMVANILRLFKIPQISYASTAPELSDNTRYDYFSRVVPPDSYQAQAMVEIVSALGWNYVSTVAANDNYGESGIEYFSRFARDTGKPPGGVCIAQSLKIPHEPKPSDFDKIIHRLL-ETPSARAIILFANEDDIKRLLEATRRANQTGHFLWVASDSWGSKIAPIRNQEDEAEGAITILPKRASVAEFDKYFTSRTLENNRRNVWFAEFWEENFKC-------RLSRHGARQTVHAKK--------------------------------------CTGQERVGRDSQYEQEGKVQFVIDAVYAMAHALHNLYQKRC-PRLSGLCVD-MEPVPTKDLLEEIRSVSFNGSAGTPVMFNKDGDAPGRYDIFQYHLHNTSTPGY--NVIGEWVNHLQLNISALQWTAGRRELPYSICSMPCASGERKKKVKGVPCCWNCERCEGYYFQLDEFNCHLCPYNMRPNVNRTGCDAIPIVKLEWHSPFAVVPVFLAILGLLTTAFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYATTFLMIAEPSLAVCSFRRIFLGLGMCVSYAALLTKTNRIYRIFEQGKRSVTAPRLISPASQLVITFSLIAVQLLGVCIWFGLTPPHTVIDYEEQRSQEAELARGMLKCDISDLALICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAE 814          
BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005888.1 (pep scaffold:Pmarinus_7.0:GL487952:898:2919:-1 gene:ENSPMAG00000005329.1 transcript:ENSPMAT00000005888.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 323.939 bits (829), Expect = 1.797e-100
Identity = 194/456 (42.54%), Postives = 249/456 (54.61%), Query Frame = 2
Query:  188 DIILGGLFPVHDSE--TELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDC-IPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLI 1546
            ++++GGLFPVH+    ++ C  IN  RGIQR+EAMLF +  IN  P +LP + +GAR+LDTC KDTYAL+Q+L+F++SSL    D +D+ C D +  + H    Q I  V+GGS SSVSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMA+++  FNWTYVSTV S GDYG++GI+AF  E++   +CIA  E +           IV  L Q+    RVVVLF R D  K LL A    N S  FLW+ASDGWG     V  N   A GAIT E+ +  ++ F+ YF  L    N  NPWF EYW+  F C +P    +    S  +SL                    N  +F ++                               SKI  V +AVYA+A+ L   Q  LC P     C  A+  IDG   YK+ I
Sbjct:    9 ELLVGGLFPVHEKGDGSKDCGPINEARGIQRMEAMLFALDRINEDPRLLPGVRLGARVLDTCLKDTYALEQALEFVRSSLQ-KVDGTDFMCPDGTYAI-HGGNAQPIAGVIGGSDSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFYQAKAMADILRFFNWTYVSTVASEGDYGETGIEAFENEARSRNICIATSEKVGRLTGPDSYKGIVHNLMQK-PNARVVVLFMRSDDAKNLLAAATSNNTS--FLWVASDGWGALENVVKGNEKAALGAITIELSSFPVQEFSEYFKSLRPTANERNPWFREYWQHKFQCTLPELPHVENECSQQRSL--------------------NDKNFEQE-------------------------------SKIMFVVNAVYAMAHALHNMQRSLC-PNTTGLC-DAMKPIDGKRLYKEFI 406          
BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Match: casr (calcium-sensing receptor [Source:ZFIN;Acc:ZDB-GENE-050119-8])

HSP 1 Score: 333.569 bits (854), Expect = 5.024e-99
Identity = 267/904 (29.54%), Postives = 425/904 (47.01%), Query Frame = 2
Query:  182 NGDIILGGLFPVH-------DS-----ETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFI-KSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIK----PNPLH--SDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNS-NVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCT-MFNFSSKLKNFKQESKIQ---SVYDAVYAVAYTLD------RFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDG--------LFLNSEVTWPGEEKEIPRSICSEDCPVGQIR-IYSKESKCCWGCSLCKSNEY--VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFES---AQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRK-KPEFPVLKCKIETKTFLVSLV-YNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTT 2755
            +GD+ LGGLFP+H       DS     E   C + N  RG++ + AM F ++EIN    +LP + +G ++ DTC+  + AL+ +L F+ ++ L          C                 +VVG + S VS  VANLL LF IPQ+SYAS+S +LS K+ +  F RT+ SD+QQA A+AELV  F WT+V  + S  DYG  GI+ F +E+++  +C+   E +     P  +H  +D++A         +  RV+V+F        L+  V   N +    WI S+ W   +        +V    + F  +   I  F  Y  ++   R+ NN +  + WE  F+C  +K +   S +  +S+ S ++          +  K   N+       PR          CT   N S+    F   + ++   +VY AVYA+A+ L       R  + L   F   KC   +  ++     + L    F ++ G  V FD  GD  G Y++ N+ ++ K G      +G +  DG        L   S+    G  +EIP S+C++ C  G  + I   E  CC+ C  C   EY    +   C  C E  WP  N T C      Y+       +    +  LG   T SV  VF  ++ T IV+A+  ELS+L+      C+L S  F+ KP+  +C +++   G+ F +  + +L KT+R+ ++FES    +   ++   +    QL++  +   VQ++  A+WL+ +PP    D   K +   L C   ++  L  ++ Y  LL  VC  +A + RK+PENFNE+KFI F+M    ++WL+FI  Y  +   F   +  + I V  S++  L C+FF K +II L+PE+N  +    ST 
Sbjct:    4 DGDLNLGGLFPIHFGVLSRADSLTVRPEAVECVRFN-FRGLRWMLAMAFAVEEINADNLLLPGLRLGYKMADTCNTVSKALEATLGFVARNKLGALGMGGVCNCTPAPRA--------NTVSVVGATSSGVSTAVANLLSLFRIPQVSYASSSRVLSNKQQYRSFMRTILSDEQQATALAELVREFGWTWVGLIASDDDYGRPGIERFREENEEEVICVEFSETVSLYDPPERIHELADMIA--------NATARVIVVFASGTDLDPLMREVARRNLTGR-TWIGSEAWVSSSLIARPEIFHVVGSTLGFVQRPGHIPGFREYLQKVHPQRHPNNVFVRQLWEATFNCT-LKAEAASSDNCTQSVQSHEQ-------GINECVKGAANA-------PRP--------FCTGRENISAVKTPFLDYTDLRITYNVYLAVYAIAHALHDMLFGCREGAGL---FEGGKCTN-IQQLEPWQLLRYLQVVRFRNNKGEEVQFDEKGDPRGGYSLVNWQQSPKDGSVQLVEVGSY--DGRKPSGQRLLCNGSKQISKGYSREIPTSVCTQPCAPGTRKGILEGEQVCCFECISCAEGEYNNESDANSCLGCPEDSWPSANHTMCVPKREEYLSWREPFGVCLAFVGCLGAVLTLSVAAVFVKHRGTAIVKATNVELSYLLFFSLFCCFLSSLFFIGKPSTVACKLRQPTFGISFVLCVSCVLVKTHRVLQVFESQIPGRGGVRKL--LGLDHQLLLVFLFTLVQVVICAVWLYTAPPTFEEDDTFKNDVIYLSCDEGSQLALGFVIGYTCLLAGVCFLFAFRARKLPENFNEAKFITFSMLVFFIVWLSFIPAYVSSQGKFVAAVEVIAILV--SSFGLLSCIFFHKCYIILLKPERNTPEEVRCSTA 856          
BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008333.1 (pep scaffold:Pmarinus_7.0:GL477638:94752:105207:1 gene:ENSPMAG00000007531.1 transcript:ENSPMAT00000008333.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 304.294 bits (778), Expect = 6.042e-89
Identity = 248/891 (27.83%), Postives = 417/891 (46.80%), Query Frame = 2
Query:  182 NGDIILGGLFPVHDSETEL------------CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVV-GGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAV---KIMNYSNYFLWIASDGWGQENGPVTNN---SNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQS--KLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFR----------HDGLFLNSEVT-WPGEEKEIPRSICSEDCPVGQIRIY-SKESKCCWGCSLCKSNEY--VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVC-YLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGI-RYDRKKPEFPVLKCKIETK---TFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
             GD+ILGG+FP+H+S   L            C  +N +R + RL  ML+TI+EINNR D+LPN+ +G R++D+C+    A++ S +F   SLS                     +TQK   VV G +YS ++I  A  L L  IP ISY++++  LS+K   P F RT+PSD  Q+KA+AELV  F WT++  + S  DYG  G+  F  ++ + GVC   +  +       D+ +IV  +  + S  +V++ F      + ++  +   +I+  +    +IAS+ W   + PV +    ++V  G I F++ + ++   + +         ++NP+  E W+E F C P                        + +   D             R P  +  +S      + + +S   N  + +   +VY AVYAVA+ L    +       F    C   L++I      + L    F D+ G  + FD+NGD V  Y +  + R K         +G +              L +N E+  W G++ + P S+C   CP G  + Y + +  CC+ C  C   E+    +   C  C    W     T C++  V Y+K      +I  I + +G   T  V+ +FY Y+ TPIV+AS  ++S ++L  CL C +L  +VF+  P P+ C  ++   G+ F+   + +L KT  +   F+ +            ++++ I AV+I +++    +W F + P + R +  K +   L+C   +     F+++ +Y + LI  C   +   RK+P NFNE KF+ F+  T  ++W++FI  Y   + S E ++    IS+ LS +  LI LFF K +II  QP+KN ++
Sbjct:   33 GGDVILGGMFPLHNSVINLPLEFNAVPTSADCVMLN-ERALTRLYTMLYTIEEINNRSDLLPNMKLGYRVIDSCTDVMKAVEASYEF---SLSG--------------------STQKPPLVVIGDAYSFLTIPAAYTLGLKHIPMISYSASAPSLSDKTRFPTFMRTIPSDTFQSKALAELVGHFGWTWIGILGSDDDYGRQGLGKFQSDAHEYGVCTDFQIWVPKKIAIKDINSIVNVI--QNSTVKVIIAFVIDAELEPIIKEMARRQIVGKT----FIASESW--ISSPVIHKPQYADVLEGTIGFDMISADMNKLSDFLRN--SKPTTDNPFMTELWQETFHCTP------------------------YPSGLVDAA-----------RLPACSGDES------LGSVTSSFFNPSEMTVPYAVYLAVYAVAHALHELTACTTWTSVFAGGHCAN-LSDIQPWQVMRYLKKVDFKDN-GYNIRFDANGDPVAYYILKQWQR-KDDENMKMVAVGSYTNLNNNTNSTNKGHLIINDELLLWMGKQLKAPDSLCVAACPEGSKKEYEAGQPSCCYRCVQCSDGEFSKTKDANNCMRCPPDSWSTGTHTDCFVKPVQYLKWDSVEGLILHIAAIIGIFLTIDVLFIFYKYRETPIVKASNFKISLMLLI-CLFCNFLCIYVFVGIPKPWMCITRQPFFGVSFSSCLSCILVKTISMIITFKPSLTRNNTFHRQMTRAEIPIVAVVIVIEVALCVVWYFLASPSVFRNENIKADTIFLQCDEGSPLNFAFIIAYLYVLALI--CLMLSFMVRKLPNNFNEGKFVMFSALTFFIVWISFIPAY---ILSNEHRVVVEVISIILSGYGILIFLFFHKCYIILFQPQKNTKE 839          
BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Match: EDO31767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWZ2])

HSP 1 Score: 508.449 bits (1308), Expect = 2.053e-164
Identity = 319/871 (36.62%), Postives = 460/871 (52.81%), Query Frame = 2
Query:  152 IDN-KYQSAIYNGDIILGGLFPVHDSETE--LCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMI--KPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKT--VEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC--KPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVT-WPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVR 2731
            IDN  + S   +GD+I+GGLF VH +  +   C  +N   GI RLEAML+ I  +N    +LPNI++GA I D C      L+QSL+ ++  L +NN      C  +  +      T     VVG SYSS++  VA+LLRLF +PQISYA+TS  LS+      F RT+P D  QA A+ +++ + NW+ V  + S G YG+ GI +F K ++K  VCI     +  K NP+  +   I++   +E S+TRVVVLF   +    +L +   +N + YF+W+ASD WG +N P+    +VANGA+T E++T   E+  F  YF QL    NS NPWF EYWE  F C      + V   S     SG    +Y                                                 + K+  V +AV + A+ L    S +C  +P +     +A    D ++ Y  L N +F  + G  + FDSNGD+ G+Y++  Y R+ +    Y + +G +    L LN SE+T W   +     S C + C  G IR  +K +KCCW C  C    +V N T C  C EG  P  +   C LL V Y+  + W A++      +G   T  V+GVF  +K+TP++ A+GRE+S L+ +G ++CY ++FV ++ P    C I+R   G+ F ++Y SLL KTNRIARIF       K P  ISPKSQL I  ++IS  L    +  +F PP I+Y   + ++ +L C  +    +  L YN+LLI +CTYYA +TRK P NFNE+KFIGF MYTTCVIW+AF+ +YFG    FE     +  S   SA   L+ +F PK++I+  +PEKN++
Sbjct:   45 IDNPSFASGQVSGDVIIGGLFSVHSAGGDKFRCGPLNEQVGIHRLEAMLYAIDLVNADHTLLPNISLGADIRDDCENINRGLEQSLNLLQGMLGNNNRN----CPARDWIKERGPITAG---VVGPSYSSLATQVASLLRLFKVPQISYAATSTELSDTHRFDYFMRTVPPDLFQALAIVDIIRAMNWSAVFAINSRGSYGEGGIQSFQKMARKANVCIVDVAQVDDKMNPV--EYTEILERFTKE-SRTRVVVLFCNTEDIHSILASASRLNLTRYFMWLASDFWGSKNEPLFGVEDVANGAMTIELQTNQRELNKFYDYFKQLRPETNSRNPWFREYWEWHFKCKLENNSLSVFNRSCSDNQSGTHHLHY-------------------------------------------------DGKVMFVVNAVLSFAHALHNLHSDICSGEPGMCYAMRQATR--DSLISY--LRNVTFNGTTGR-IQFDSNGDTSGKYDVLQYRRDGEDDGRYVR-VGSWIEGELKLNTSEITEWYVSDSNAIESHCGKPCKPGYIRRMTK-AKCCWSCEWCSLGSFVYNNT-CIRCKEGYQPDTSYQDCTLLPVKYLD-TPWKAVVATAAG-VGVVVTMFVIGVFIKFKDTPLIMAAGREVSTLLFTGMIMCYALAFVMVVPPNTTLCGIRRFGTGISFCLLYTSLLVKTNRIARIFSGT----KSPSFISPKSQLFITLLIISPVLTITLLEFYFHPPKIKYTHLE-KYNLLSCSNKEIAVITKLCYNVLLILLCTYYAFRTRKTPLNFNEAKFIGFCMYTTCVIWIAFLPLYFGAGGGFEGL--AVCFSAVFSATTILVFIFAPKVYIVIFKPEKNLK 839          
BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Match: EDO35253 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM25])

HSP 1 Score: 493.041 bits (1268), Expect = 1.821e-159
Identity = 300/866 (34.64%), Postives = 454/866 (52.42%), Query Frame = 2
Query:  185 GDIILGGLFPVHDS-ET---ELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLT-YNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEE---------KEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFP-----VLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKN 2725
             DI+LGGLFPVH   ET   + C +++ +RG+QRLEAM+F I+E+N    +LPN+ +GA I DTC  DT  L+++L+FI  SLS  N  +   C    E    T     +  V+G + SSVSI VANLLRLF +PQISYASTS  LS K  +  F RT+PSD  QA+ + +++ + NW+ V TV S G+YG+ GI+ F   +K+  +C+     I+ +        +++   +E +  R VVLF   +  + LLNA + +     F WIASD WG  +G V    ++A GAIT  ++++    +  YF  LT  N +  NPWF+E+WE+ F                K  ++G  S    +T+ +                                      K    ++K+  V DAV A A  LD      C P     C   +   +G      L N SF    G  V FDS GD+ G Y+++ +  N+    Y Y  +  +     F++  +   G +             +S C E C  G  R   ++  CCW C  C  +EYV ++T C  C E E P   RTGC LL + Y+  S W +I+    + +G      V  +F  +  TP+V+ASGREL+  +L G  +CY+   + +L+P+ + C +QR  +G    V YA+LL KTNRIARIF  ++++ K P  I+P SQL+I A ++ V+++   + L +  P     ++  +FP     +  C I+    +V++ YN+LLI +CT YA +TRK P NFNE+++IGF MYTTCVIWLAF+ +  G ++  + +  TL I+V+L+A   L+C+F PK++I+  +P +N
Sbjct:    4 ADIVLGGLFPVHSRLETAVGQTCGELSSERGVQRLEAMIFAIKEVNKNTTLLPNLTLGALIHDTCGTDTIGLEETLEFIMDSLSRQNLPTQQ-CSGVDENFNKTL----LAGVIGAASSSVSIQVANLLRLFKMPQISYASTSPDLSNKHRYDFFMRTVPSDAFQARVIRDVIRALNWSAVFTVNSKGNYGERGIEEFHMLAKEANICVVEAVTIEHSFTAEAFDDVIRRFMRE-TGMRGVVLFCTDNDIRKLLNAAERVQAEGRFSWIASDYWGTRHGLVKGRESLAKGAITITLRSIPHTEYREYFTSLTPTNYSKANPWFEEFWEKNF----------------KCKLTGNSSTCPANTSLS--------------------------------------KEMYIDNKVPFVIDAVRAFATGLDVLYRNKC-PNTDGLCEDLMRQNNGEELMSILQNISFQGVSGE-VKFDSQGDATGMYDVFTF--NQTESGYNYIKVATWDGGLHFVDPALQAGGLDLGGEGVLLNPSGVQSSCGEPCARGYYRKLRRDKACCWTCLPCGKDEYVKDLTGCGRCTELERPDPTRTGCVLLPLRYLSDS-W-SIMVTCFATVGIICVLGVSVIFIMFSETPLVKASGRELTATLLIGLFLCYVEGIMLILRPSVFVCGLQRFGVGFAPCVCYAALLIKTNRIARIFAKSERSTKPPDFINPASQLLILAAVVGVEVVLAGVGLGYWSP-----KQTEKFPTKSDILSTCNIQDYDLVVAMSYNVLLILLCTIYAFRTRKTPANFNEARYIGFAMYTTCVIWLAFLPVQIG-VNDKDYKTLTLSINVTLNATTLLLCVFGPKVYIVLFRPTRN 797          
BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Match: EDO41315 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4N3])

HSP 1 Score: 452.21 bits (1162), Expect = 9.024e-144
Identity = 306/868 (35.25%), Postives = 450/868 (51.84%), Query Frame = 2
Query:  185 GDIILGGLFPVHDSETEL-CKKINPDRGIQRLEAMLFTIQEINNRPDILPN-INIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIR--IYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQ--NRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPT 2770
            GDI+LGGL PVH    +L C ++    GIQRLEA+L+ + +IN     L N I +G ++ DTCS +T AL +SL+FI S L             KSE       + ++  ++G +YSSVSI +A L RLF IPQISY STS  LS+KK    F+RT+P D  QAKA+ +++  FNWTYVS V S   YG  G+DA    + + G+C+A+   ++ +   S  L +V ++  E    R V++F ++   + LL+AV++ N ++   ++ SD WG     + +  +VA   IT   K+V +K F  YF  L+   NS NPWF EYWE  F+C                  S  E+   + T   D  K +                               L N   + +I S  DAVYA A+ L+   + LC+ + +  C  A+ NI G      + N SF  + G  V FD+NGD  G Y++  +   K +G Y    IG ++ D L + +E      + EI +S CS++C   ++   +  KE+ CCW C  CK N YV+N T C  C  G WP    +R  C  + + Y   +   A+  M  +  G   T  V+ +   +  TPIV+A GREL++L+L   L+C+  +F+ +L+PT   C  +  L  LGF + YA++  KTNRI+RIF   +  AKRP  + P SQL++   ++ VQ L   +      P  R+     +   L C      F +S VYN +LI +CT YA KTRKIP NFNE+K I F MY++CVIWLAF+ +YF    S   +   L IS+SL A+V L  L+ PK++I+  +P +N  K    +  + +P 
Sbjct:    3 GDILLGGLVPVHSKNVDLQCGELQERLGIQRLEALLYALDKINAANSTLLNGITLGLQLYDTCSSETMALDKSLNFIYSQL-------------KSE-----STSSRVVGIIGAAYSSVSIQIARLSRLFEIPQISYDSTSFELSDKKRFGFFSRTVPHDNFQAKALVDVLKYFNWTYVSVVYSDDSYGILGVDALRSAATRAGICMASSHKVRSSGHESTYLLVVDSILSE-PLARTVIVFAQVHQIRGLLHAVQVRNAADQLQFVGSDAWGNVVW-LKDLQSVALNTITVSPKSVRLKGFEEYFTSLSPINNSRNPWFQEYWEHHFNC------------------SLNETLGKYPTKCNDSLKLS-------------------------------LGNSDIDMRIASAIDAVYAFAHALEAMHADLCR-YTVGVC-PAMENISGSELLGYIRNASFVGATGEKVHFDANGDVEGIYDVMRF--EKSSGTYRNVIIGTWK-DKLRMRNE-----HKFEIVKSSCSDECSSDEVMLPVRGKEA-CCWSCEPCKGNSYVINRTTCLTCPLGSWPNHSADRKQCLQIELQYFGKNLMYAVPAMGFAGTGIFITIFVVYLLAKHDKTPIVKACGRELAYLLLVSILLCFSDTFIVVLRPTRIICIARFFLSSLGFTISYAAIFIKTNRISRIFNR-RNVAKRPILVLPSSQLVLVLGVVCVQALFLVLLTLLRTPTARHFYPTVDTVYLSCSTSDLDFGLSQVYNFILIIMCTVYAFKTRKIPSNFNEAKLIAFAMYSSCVIWLAFLAVYF-MQRSLVERPLILSISISLIAYVLLGSLYGPKVYILIFRPHRNKTKTETRTIAFSRPA 788          
BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Match: EDO48665 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIA2])

HSP 1 Score: 449.129 bits (1154), Expect = 2.629e-141
Identity = 288/859 (33.53%), Postives = 420/859 (48.89%), Query Frame = 2
Query:  185 GDIILGGLFPVH----DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQ-EFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTD-SYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEF---------RHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIR-IYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQI-STLGISVSLSAWVTLICLFFPKLHIIF 2707
            GD+I+GGLFPVH     SE   C  I+   G Q L AMLF ++ INN   +L NI +GA I DTC   T     + D IK SL  NN                    + ++ VVG   S VSI    LLR+F +PQ+S+ STS  LS K  +  F RT+P D  QA+A+ +++    W Y+ T+ S+G+YG++G+ A  K ++K  +CIAA   + P    +    I++ + Q  F    ++V+FT    +  LL+A   +  +  F W+ S+GW         N  VANG+IT      ++  F  +F  +    N N PW DE+WE  F C                L  GK ++Y    N T+           D   P+                        + + ++ V +AVYA A+ LD  Q  LC P  +  C   + +  G      L N +F D SYG  V F+ N +  G Y+I N+    + GK+ Y+N+G +         R + L L S+ ++W   +   P SICS  C   QIR       KCCW CS C  ++ VVN   C+ C  G  PY N + C  L V +  L   + I   + S LG   T ++   F   +   +V+A+GREL  +IL G ++CY   F  L++P   +C ++R    + +   YA LL KTNRI RIF  A+K A RP   SP SQ+++ A LI+VQLL   +W   SP  I    ++    V+ C+       ++L YN+LL+ +CT +A KTR  P NFNE+K+IG  MY TC  W+ ++  Y  T H    Q+    G+SV++ A +TL  +F PK+H+I 
Sbjct:   99 GDVIIGGLFPVHLKNQKSENS-CGPISTQPGFQYLAAMLFALELINNSSTLLRNITLGASIYDTCQSQTIGADHAKDIIKESLLTNN--------------------KLLKGVVGPLVSDVSIATVQLLRVFGLPQVSFGSTSPDLSNKDLYGSFFRTVPPDSFQAEALVDILEHHGWNYIITINSAGNYGENGMSAIIKITEKRDICIAATFTVPPLSTDAHYERIIREIAQARFDAVNIIVVFTTQTDSAGLLSAAARLG-ATRFTWLGSNGWSNRMTVTIGNEMVANGSITVNHMDGQVAGFEEFFSSMNPINNQNIPWIDEFWENWFKC---------------DLPGGKPTFY---KNCTE-----------DLVLPK-----------------------MEVAPVRVVINAVYAFAHALDDMQRALC-PGKVGLCEAMIADSSGKTLIDFLRNVTFPDASYGWPVRFNKNQEMDGNYSIMNF--QYQNGKWIYENVGSWSWGDESDNVRMEHLILESQKISWGKGKLSPPHSICSAPCQFPQIRNQLPVNPKCCWECSFCDEHQIVVN-DSCQSCLPGHRPYTNHSMCVKLPVVHPSLGEAMGITFAVWSCLGMLVTLAICVFFVKSREHEVVKAAGRELCAIILLGIMLCYASIFTNLVEPDAITCTVERFFSSVCYTTCYAPLLMKTNRIYRIFSRARKAASRPHLTSPTSQVLVTAGLIAVQLLLTTVWTISSPSHIHITYERLTRTVISCESHGGMLALNLSYNILLMLICTLFAFKTRNFPRNFNEAKYIGVMMYLTCAAWIIYLPSYLNT-HDVWAQVYLNCGVSVTI-ATITLAGIFAPKVHVII 877          
BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Match: EDO47627 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLL8])

HSP 1 Score: 441.039 bits (1133), Expect = 4.866e-138
Identity = 300/962 (31.19%), Postives = 458/962 (47.61%), Query Frame = 2
Query:   95 LPIVIYYSFFVTVNL--IASEIDNKYQSAIYNGDIILGGLFPVHDSETEL---CKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSK----TRVVVLF-TRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNL-VSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEF----------RHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYS-KESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMK-LSGWLA-IIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGI---RYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTL-GISVSLSAWVTLICLFFPKLHIIF----LQPEKNVRKLTMSSTTYRKPTNSSGSFANHR------EMNSEYTPLPPPFNSQSHHLVV 2866
            L   + ++ F+  N     SEI++     +  GD+ILGGLF VH   T     C  I+ + G Q   A +F I EIN  P+ILP + +GARI DTC   T     +++ IK +L D                  T +T  +  V+G   S V++ VANLL +F+IPQ+S+ +T+  LS K+ +  F RT+P +  Q +A+ ++V  F W+YV TV S GDYG+ G+D     + K GVCIA    + P P   D  A +K+L     K      VVV+F  + D+T L+  A K++N +N F+++AS+ WG+ +    NN     GA+T       +K F  +   LT   + N+ WF E+W+   +C                    K S+  +  N T   + N+         PR   +                      + ++   +AVYA A+ L    + LC P     C     N+    + K L N +F D+  N+ V F+ NG+  G Y+I N+   K  GKY Y  +G +            D     S ++W       P S CS  C + QI   +     CCW C  CK  +Y+ N T C  C +G  P  N T CY L V Y    +G  A I+  ++  LG+ +T      F   K+  +++ASGRELS ++    L CYL +  ++ +PT + C ++R    +     YA +L +TNRI RIF +AQK+  RP   SP SQ+M C  +I+VQ+L   +W    PP      YD +     +L+C +   +  ++L YN+ L+ V T YA KTR  P NFNE+K+IG TMY +C +W+ F+  Y    +S  +  ST+  +++   A VTL+ L  P+++++     + PE     ++ +S  +   +N SGS    R      E   +    P P  +  HH VV
Sbjct:   44 LSCAVVFAVFIVANSGEFVSEIEDNRGPIVLEGDVILGGLFNVHSRSTTTENGCGSIDLNPGFQYYAAAVFAIDEINKNPNILPGVKLGARIYDTCRSQTIGGDDAMEIIKYTLLD-----------------RTNSTPPLAGVIGPFRSDVAVAVANLLGVFNIPQVSFGATTTKLSNKQIYKYFFRTVPPNSFQGRALVDVVRYFKWSYVMTVHSHGDYGEPGMDEVKSAAAKHGVCIAGDYKLPPFPKEEDFEATIKSLLDLSKKHSDTVHVVVMFCIQRDNTGLVRAAKKLLNENNRFIFVASNSWGERHPVTNNNEEGGEGALTLNFIDGNVKRFKDHLLSLT-PLDDNSTWFHEFWQISMNC--------------------KLSFAKWQFNTTKECRLNE-------MLPRDFGI----------------------APVRVSINAVYAAAHALHNMYTNLC-PKQSGMC-DEFRNLKRENYLKFLRNVTFPDAASNVTVRFNRNGEVDGNYSIVNF--RKVDGKYTYLKVGSWGGVLKPDDSIEGDATIDESRISWKPRWNIAPDSYCSSPCSIRQITAPAIANPTCCWQCVDCKHKQYISNDT-CLSCPDGHTPDANLTSCYKLPVVYATPFNGNTAQIVTFVVVLLGSISTICTGVFFLKNKDNRVIKASGRELSAILFIATLCCYLSAISYMTRPTDFLCGMRRFSGSVSLTACYAPVLLRTNRIHRIFTAAQKSVTRPSFTSPMSQVMFCLGIIAVQVLITCVWFLSDPPRAVMSYYDERT----LLECGMSDTSVAMNLCYNIFLMLVATVYAFKTRNFPRNFNEAKYIGITMYISCAVWIIFLPCYLNAANS--IWKSTMKAVALVAIATVTLLGLLVPRMYLVIHGATVGPETLTMTMSQNSKGHELHSNLSGSGRAGRYQTQAEEGTVKEEVSPRPRANSIHHQVV 927          
BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Match: grm2a (glutamate metabotropic receptor 2 [Source:NCBI gene;Acc:101169193])

HSP 1 Score: 679.093 bits (1751), Expect = 0.000e+0
Identity = 383/868 (44.12%), Postives = 518/868 (59.68%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSY-----GNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTY 2758
            GD+++GGLFPVH      E C KIN  RGIQRLEAML  + EIN    ILP I +GA ILDTCSKDTYAL+QSL+F+++SL+  +D S+Y C D S  + H      I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +        ++++L Q+ S  RVV+LFTR +  + LL A   MN +  F W+ASDGWG +   V  +  VA+GA T E+ + EI  F  YF  L    NS NPWF E+WE  F C            S+  L  GK                                            FS +   F+ ESKI  V +AVYA+A  L   +  LC P   + C  AL   +G  FY+D ++   F   +      N+V FD+ GDS+G+YNI++Y  +K+ G+Y Y+ +G +   GL LN+ +  P  ++ +P S CS+ C   +++       CCW C  C+  +Y+++   C  C+ G+WP  N TGCY L   Y++     AI P+ +S LG  +T  V+G+F  +  TP+V+ASGRELS+++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ IC  LIS QL+   +WL    PG+R +   ++ +   LKC     + L+SL YN +LI +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L  ++T +
Sbjct:   26 GDLMIGGLFPVHQKGEGAEDCGKINAQRGIQRLEAMLLALDEINKNERILPGIKLGAHILDTCSKDTYALEQSLEFVRASLTKVDD-SEYTCPDGSYAI-HDDVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKTRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARARQICIATSAKVSRSMSRWSYENVIRSLQQK-SNARVVILFTRSEDARELLVAANRMNVT--FTWVASDGWGAQESVVRGSEAVADGAFTIELASYEIPQFNEYFTGLHPYNNSRNPWFREFWENQFQC------------SLHDLGCGK--------------------------------------------FSLRDVPFQPESKIMFVVNAVYAMAAALHNMRQALC-PNSTKVC-DALKPGNGRKFYRDYILKVKFEAPFRPPDTENVVRFDAFGDSLGRYNIFHY--HKENGRYVYRKVG-YWAQGLILNTSLI-PWADQAVPNSQCSDPCRKNEVKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPLANLTGCYDLPEEYIRWEDAWAIGPVTISCLGMMSTLFVIGLFLKHNETPVVKASGRELSYILLLGVLMCYCMTFIYIAKPSTAVCTLRRLGLGTSFAVCYSALLTKTNRIARIFGGVKDGAQRPRFISPASQVAICGALISCQLVVVVVWLLLEAPGVRKEVSPERRDVVTLKCNNRDSSMLLSLTYNCILIILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVCTLRAATTRF 826          
BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Match: grm2a (glutamate metabotropic receptor 2 [Source:NCBI gene;Acc:101169193])

HSP 1 Score: 678.322 bits (1749), Expect = 0.000e+0
Identity = 383/868 (44.12%), Postives = 518/868 (59.68%), Query Frame = 2
Query:  185 GDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSY-----GNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYD--RKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTY 2758
            GD+++GGLFPVH      E C KIN  RGIQRLEAML  + EIN    ILP I +GA ILDTCSKDTYAL+QSL+F+++SL+  +D S+Y C D S  + H      I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +        ++++L Q+ S  RVV+LFTR +  + LL A   MN +  F W+ASDGWG +   V  +  VA+GA T E+ + EI  F  YF  L    NS NPWF E+WE  F C            S+  L  GK                                            FS +   F+ ESKI  V +AVYA+A  L   +  LC P   + C  AL   +G  FY+D ++   F   +      N+V FD+ GDS+G+YNI++Y  +K+ G+Y Y+ +G +   GL LN+ +  P  ++ +P S CS+ C   +++       CCW C  C+  +Y+++   C  C+ G+WP  N TGCY L   Y++     AI P+ +S LG  +T  V+G+F  +  TP+V+ASGRELS+++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ IC  LIS QL+   +WL    PG+R +   ++ +   LKC     + L+SL YN +LI +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L  ++T +
Sbjct:   57 GDLMIGGLFPVHQKGEGAEDCGKINAQRGIQRLEAMLLALDEINKNERILPGIKLGAHILDTCSKDTYALEQSLEFVRASLTKVDD-SEYTCPDGSYAI-HDDVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKTRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARARQICIATSAKVSRSMSRWSYENVIRSLQQK-SNARVVILFTRSEDARELLVAANRMNVT--FTWVASDGWGAQESVVRGSEAVADGAFTIELASYEIPQFNEYFTGLHPYNNSRNPWFREFWENQFQC------------SLHDLGCGK--------------------------------------------FSLRDVPFQPESKIMFVVNAVYAMAAALHNMRQALC-PNSTKVC-DALKPGNGRKFYRDYILKVKFEAPFRPPDTENVVRFDAFGDSLGRYNIFHY--HKENGRYVYRKVG-YWAQGLILNTSLI-PWADQAVPNSQCSDPCRKNEVKSMQPGDVCCWICIPCQPYQYLLDEFTCADCSFGQWPLANLTGCYDLPEEYIRWEDAWAIGPVTISCLGMMSTLFVIGLFLKHNETPVVKASGRELSYILLLGVLMCYCMTFIYIAKPSTAVCTLRRLGLGTSFAVCYSALLTKTNRIARIFGGVKDGAQRPRFISPASQVAICGALISCQLVVVVVWLLLEAPGVRKEVSPERRDVVTLKCNNRDSSMLLSLTYNCILIILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKIHIILFQPQKNVCTLRAATTRF 857          
BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Match: grm2b (metabotropic glutamate receptor 2-like [Source:NCBI gene;Acc:101174659])

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 375/876 (42.81%), Postives = 511/876 (58.33%), Query Frame = 2
Query:  176 IYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLI---------NNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY----DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTY 2758
            I +GD+++GGLFPVH+     E C KIN +RGIQRLEAML  + EIN+   ILP + +GA ILDTCSKDTYAL+QSLDF+++SL+  +D   + C D S  ++  +    I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +        ++++L Q+ S  +VV+LFTR +  + LL A   MN S  F W+ASDGWG +   V  +   A+GA T E+ +  I+ F  YF +L    N+ NPWF E+WE  F C     ++     S +SL  G                                                    F+QESKI  V +AVYA+A+ L   +  +C      K   A+   +G  FYK+ I           + TDS   +V FDS GD + +YNI++Y  +K+ GK+ Y+ +G +        S + W G     P S CS+ C   +++       CCW C  C+  +Y+ +   C  C+ G+WP  N TGCY L   Y++     AI P+ +S LG   T +V+G+F  +  TP+V+ASGREL++++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ IC  LIS QLL   IWL    PG+R     DR+      LKC     + L+SL YN +LI +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L +++  +
Sbjct:   22 IMDGDLVIGGLFPVHEKGDGMEDCGKINEERGIQRLEAMLLALDEINSSDRILPGLQLGAHILDTCSKDTYALEQSLDFVRASLTKVHDPG-FICPDGSRPVQK-EVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKTRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARTRQICIATSAKVSRSMNRQGYENVIRSLQQK-SNAKVVILFTRSEDARELLVAAARMNAS--FTWVASDGWGAQESVVRGSETGADGAFTIELASYPIREFEDYFTKLNPYTNTRNPWFREFWEHKFGC-----RLEEHGCSDRSLRDG---------------------------------------------------TFEQESKIMFVVNAVYAMAFALHNMRQAVCSN--TSKVCDAMKPGNGRRFYKEFILKTKFEAPFRPADTDS---MVRFDSFGDGISRYNIFHY--HKEDGKFTYRKVGYWDQILTLNTSLIPWRGLVP--PTSQCSDPCRKNEVKSMQPGDVCCWICIPCQPYQYLQDEFTCADCSFGQWPLANLTGCYELPEEYIRWEDAWAIGPVAISCLGIMCTLTVVGLFLKHNETPVVKASGRELTYILLLGVLMCYSITFIYIAKPSTTVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKDGAQRPRFISPASQVAICGALISCQLLVAVIWLLVEVPGVRKEVTPDRRN--VVTLKCNSRDTSMLMSLTYNCILIILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKVHIILFQPQKNVATLRVTANRF 825          
BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Match: grm3 (metabotropic glutamate receptor 3 [Source:NCBI gene;Acc:101166047])

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 376/894 (42.06%), Postives = 534/894 (59.73%), Query Frame = 2
Query:  182 NGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKD-LINNSFTDSYG-----NLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE-VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAK--RPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDR--KKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHREMNSEYTP 2824
             GD++LGGLFPVH+  +  E C ++N DRGIQRLEAMLF I  IN    +LP + +G  ILDTCSKDTYAL+Q+L+F+++SL+  +D +++ C D S  L+   +   I  V+GGS+SSVSI VANLLRLF IPQISYASTSA LS+K  +  F+RT+P D  QAKAMAE++  FNWTYVSTV S GDYG++GI+AF +E++   +CIA  E +  +       A+++ L Q+    RV VLF R D  + LL A   +N S  F+W+ASDGWG +   V  N   A GAIT E+    +  F  YF  L   RN  NPW+ E+WE+ F C                 + G       H   + +   +QN                          S    +F+ ESKI  V +AVYA+A+ L   Q  LC  F   K    +  +DG   Y+D ++N SF   +       +V FD+ GD +G+YNI++Y R+ +  +Y Y  +GE+  + L LNS+ + WP E   +P S CS+ C   +++       CCW C+ C+++EY+ +   C  CA G+WP  + T CY L   Y+      AI P+ ++ +G   T  V+ VF  + NTP+V+ASGREL +++LSG  + Y ++F+FL KP+P  CA++R+ LG  FAV Y++LLTKTNRIARIF   ++ A   RP  ISP SQ+ IC  LISVQL+   +WL    PG R     ++ +  +LKC +   + L+SL Y++LL+ +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF+ I++ T   + VQ +T+ ISVSLS +V L C+F PK+HII  QP+KNV    ++   +   + ++ ++A+H  +++ + P
Sbjct:   32 EGDLVLGGLFPVHEKGAGMEECGRVNEDRGIQRLEAMLFAIDRINTDNSLLPGVTLGVHILDTCSKDTYALEQALEFVRASLTKVDD-TEFICPDGSYALQE-DSPLAIAGVIGGSFSSVSIQVANLLRLFQIPQISYASTSAKLSDKTRYDYFSRTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARMRNICIATSEKVGRSNAKKSYEAVIRQLLQK-PNARVAVLFLRSDDARELLAAAARLNTS--FIWVASDGWGAQESIVKGNEVTAEGAITLELVANPLPEFNRYFLSLNPVRNHRNPWYKEFWEQRFQCS----------------LGGSSG----HGETSHMPPCDQN-------------------------LSIDKNHFEPESKIMFVVNAVYAMAHALHNMQRSLC--FNTSKLCDGMKPLDGRKLYRDYILNVSFPAPFSPSGSETVVKFDTQGDGMGRYNIFSYQRSSE--RYGYVPVGEW-AETLTLNSDLIHWPREV--VPTSQCSDPCERNEMKKMQAGEYCCWICTACEAHEYLADEFTCAPCAPGQWPTDDLTSCYDLPEDYIMWEDAWAIGPITIACVGFMCTGLVIWVFIRHNNTPLVKASGRELCYILLSGVFMSYAMTFLFLAKPSPAICALRRLGLGTSFAVCYSALLTKTNRIARIFNGVKEGAGAVRPRFISPFSQVFICLSLISVQLVMVTVWLLLEVPGTRRFTLPERRQTVILKCNVRDSSMLLSLGYDVLLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCMFAPKVHIIMFQPQKNVTSHRLNLNRFSV-SGAAATYASHASVSAHFVP 867          
BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Match: grm2b (metabotropic glutamate receptor 2-like [Source:NCBI gene;Acc:101174659])

HSP 1 Score: 671.774 bits (1732), Expect = 0.000e+0
Identity = 375/876 (42.81%), Postives = 511/876 (58.33%), Query Frame = 2
Query:  176 IYNGDIILGGLFPVHD--SETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLI---------NNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRY----DRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTY 2758
            I +GD+++GGLFPVH+     E C KIN +RGIQRLEAML  + EIN+   ILP + +GA ILDTCSKDTYAL+QSLDF+++SL+  +D   + C D S  ++  +    I  V+GGSYS VSI VANLLRLF IPQISYASTSA LS+K  +  FART+P D  QAKAMAE++  FNWTYVSTV S GDYG++GIDAF +E++   +CIA    +  +        ++++L Q+ S  +VV+LFTR +  + LL A   MN S  F W+ASDGWG +   V  +   A+GA T E+ +  I+ F  YF +L    N+ NPWF E+WE  F C     ++     S +SL  G                                                    F+QESKI  V +AVYA+A+ L   +  +C      K   A+   +G  FYK+ I           + TDS   +V FDS GD + +YNI++Y  +K+ GK+ Y+ +G +        S + W G     P S CS+ C   +++       CCW C  C+  +Y+ +   C  C+ G+WP  N TGCY L   Y++     AI P+ +S LG   T +V+G+F  +  TP+V+ASGREL++++L G L+CY ++F+++ KP+   C ++R+ LG  FAV Y++LLTKTNRIARIF   +  A+RP  ISP SQ+ IC  LIS QLL   IWL    PG+R     DR+      LKC     + L+SL YN +LI +CT YA KTRK PENFNE+KFIGFTMYTTC+IWLAF  I++ T   + VQ +T+ ISVSLS  V L CLF PK+HII  QP+KNV  L +++  +
Sbjct:   45 IMDGDLVIGGLFPVHEKGDGMEDCGKINEERGIQRLEAMLLALDEINSSDRILPGLQLGAHILDTCSKDTYALEQSLDFVRASLTKVHDPG-FICPDGSRPVQK-EVPLAISGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKTRYDYFARTVPPDFYQAKAMAEILRYFNWTYVSTVASEGDYGETGIDAFQQEARTRQICIATSAKVSRSMNRQGYENVIRSLQQK-SNAKVVILFTRSEDARELLVAAARMNAS--FTWVASDGWGAQESVVRGSETGADGAFTIELASYPIREFEDYFTKLNPYTNTRNPWFREFWEHKFGC-----RLEEHGCSDRSLRDG---------------------------------------------------TFEQESKIMFVVNAVYAMAFALHNMRQAVCSN--TSKVCDAMKPGNGRRFYKEFILKTKFEAPFRPADTDS---MVRFDSFGDGISRYNIFHY--HKEDGKFTYRKVGYWDQILTLNTSLIPWRGLVP--PTSQCSDPCRKNEVKSMQPGDVCCWICIPCQPYQYLQDEFTCADCSFGQWPLANLTGCYELPEEYIRWEDAWAIGPVAISCLGIMCTLTVVGLFLKHNETPVVKASGRELTYILLLGVLMCYSITFIYIAKPSTTVCTLRRLGLGTSFAVCYSALLTKTNRIARIFSGVKDGAQRPRFISPASQVAICGALISCQLLVAVIWLLVEVPGVRKEVTPDRRN--VVTLKCNSRDTSMLMSLTYNCILIILCTVYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFQPIFYVTASDYRVQTTTMCISVSLSGSVVLGCLFAPKVHIILFQPQKNVATLRVTANRF 848          
BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Match: SMESG000033752.1 (SMESG000033752.1)

HSP 1 Score: 1823.14 bits (4721), Expect = 0.000e+0
Identity = 885/913 (96.93%), Postives = 893/913 (97.81%), Query Frame = 2
Query:   65 MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHRE 2803
            MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMS K++     T FT ++            FPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQ+KLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNE+VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSF+FLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHR+
Sbjct:    1 MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSEKKAI----TTFTQISPI----------FPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQAKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEFVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFIFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHRK 899          
BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Match: SMESG000033752.1 (SMESG000033752.1)

HSP 1 Score: 1813.51 bits (4696), Expect = 0.000e+0
Identity = 880/913 (96.39%), Postives = 884/913 (96.82%), Query Frame = 2
Query:   65 MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHRE 2803
            MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVK                             DYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQ+KLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNE+VVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSF+FLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHR+
Sbjct:    1 MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFPVHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVK-----------------------------DYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQAKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEFVVNMTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFIFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRKPTNSSGSFANHRK 884          
BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Match: SMESG000022915.1 (SMESG000022915.1)

HSP 1 Score: 458.759 bits (1179), Expect = 7.244e-144
Identity = 300/883 (33.98%), Postives = 445/883 (50.40%), Query Frame = 2
Query:  161 KYQSAIYNGDIILGGLFPVH-DSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDTCSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVVGGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEMIKPNPLHSDLLAI---------VKTLYQEFSKTRV--VVLFTRLDHTKLLLNAVKIMNYSNYFLWIASDGWGQENGPV------TNNSNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLCKPFVLEK-CVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDS-NGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLN-SEVTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVN-MTKCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAVLISVQLLSNAIWLFF--SPPGIRYDRKKPEFPVLKCK-IETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRK 2734
            K Q A+ +GDI LGGL  VH  SE  +C  I  + GIQ LE M++TI  +N    IL +I +GA I D C +DTY L+Q++DFIK S       S    K      +     + I  V+G S S  SI VA+LL+LF IPQIS+ STS  LS K   P F RT+PSD  Q + M E++    W YVS +    +YG     A  +  K   +CIA  E++   P  S L ++         +K   + F       V++F         + A+K  N ++ F W+ SDGW             T+      GAI  E  +  +  F  YF  LT + N +NPWF+E+WE+ F+C                L +  ++ Y    NFTD+  +N        +  + N   S                   E+++Q V DAV A A  L   ++++C P + +  C+  L N  G    + L    FT   G  + F     D + +Y I N+I+    G Y +  IG + +  L ++ +++ + G+   IP S C+  C   Q +        CW C  C+  E   N  T CE C  G++P QNRT C  L   Y+  +  L+I  MI S +      +   +F +Y  TPIV+AS RELSF++L G ++C++VS V    PT   C+ Q+  +G  F++ Y++LL K NRI RIF   +K  ++   IS +SQ+ ICA ++S+Q++     L+F  S P   +  +  E+  L C  I   + ++ +++ M+LI +CT YA  TR IPE FNESK IGFTMY+TCV+WL FI  Y  T     ++++TL +S+++SA V L CLF PK++ I  +P++NVRK
Sbjct:   40 KNQVALIDGDIFLGGLMMVHLRSEEMVCGVIAAEGGIQALEVMVYTINRVNEM-KILGDIKLGAYIKDDCDRDTYGLEQAVDFIKQS-------SKLQTKSNCNEAKIDSNLRTITGVIGASSSVTSIHVASLLKLFDIPQISFFSTSPALSNKNRFPFFLRTIPSDAHQVQVMLEIIKQLQWKYVSIIYEDSNYGREAFKALQEVFKDNRICIATSEIL---PRDSKLASVKEYKDKVLRLKKHLKTFDGVGATGVIIFGSDQEVGDFMMAIKEHNLTHSFNWLGSDGWSGRRVAYKKGLFETSKEQEIEGAIGIEPLSKTVFGFENYFLNLTPSTNKHNPWFNEFWEDFFEC---------------KLPNSSDTPY---NNFTDICDEN-------LKLSKDNPKHSF------------------ENQLQFVSDAVMAFAMALKEMKNQMCAPNISKNACISMLQN-KGETLLRILQKIKFTSLSGLEMEFTPITFDGLPRYRILNFIK-AANGIYSWVEIGNYTNQKLRIDYTKLKFRGDSSVIPISSCTPKCSDDQRKKLHPGICTCWICIKCQEYEIFKNSRTICEACPLGQYPDQNRTLCLRLQQIYLNQTHPLSIGLMIFSGICLIIALTCFFIFVFYFKTPIVKASSRELSFILLVGIILCFVVSLVLCTTPTKLMCSFQKFGIGFSFSLCYSALLVKLNRIERIFRKGRKQPQKLRLISQQSQIFICAFIVSIQIIILGTLLYFVNSDPVTHHPSRNEEY--LICDYIIGNSLVIIVLHPMILILICTVYAFLTRNIPEAFNESKHIGFTMYSTCVVWLGFIPCYLATAIMVHLRVATLCVSINVSALVALSCLFGPKVYTILFKPKQNVRK 864          
BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Match: SMESG000064049.1 (SMESG000064049.1)

HSP 1 Score: 360.533 bits (924), Expect = 2.689e-108
Identity = 230/735 (31.29%), Postives = 372/735 (50.61%), Query Frame = 2
Query:  641 RTLPSDQQQAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKL-GVCIAAKEMIKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDH-TKLLLNAVKIMNYSNYFLWIASDGWGQEN---GPVTNN----SNVANGAITFEVKTVEIKNFTTYFHQLTYNRNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFTDVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSVYDAVYAVAYTLDRFQSKLC--KPFVLEKCVKALNNIDGMVFYKDLINNSFTDSYGNLVSFDSNGDSVGQYNI--YNYIRNKKTGK--YYYKNIGEFRHDGLFLNSE-VTWP-GEEKEIP-----RSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMT----KCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSVMGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQRILLGLGFAVMYASLLTKTNRIARIFESAQK--TAKRPPCISPKSQLMICAVLISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNMLLISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSFEVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYR 2761
            R +PSD  Q KA+  L+  F W+Y+S + S G YG+ GI    +  K    +C      I          A+   L+++  K +V++ F + D  TKLL +  K+      +L I +DGW       G + N     S  A G+IT  + +  I +F  YF   T +    NPWF E+WE+ F+C                           H N T  +K           +P++ + K      ++FN       + Q+SK+  V  +V  +A+ L     K+C  K F LE C   +   +G +   ++I+  F+      V FDS GD  G+Y+I  Y Y  N+KT +  Y+Y+ IG ++ + L +    + WP  EE E       +S CS+ C   QIRI+ +  KCCW C  C  NE + N T     C  C +G  P  +R+ C  +   ++K S    I+ +I S +G   T  ++G+F  Y NTP+V++  REL ++IL G  + YL +F  + KPT +SC + RI+ GL F++++ SL+TKTNRI RI   ++K    ++   ++  +Q++I  +L  V+++  ++ ++ + P  + D        L C  E++   +S+ ++ +L+  CT+YA KTR +PENFNE+KFIGFTMYTTC+IW+  + IY  T     ++  +L  ++  +A + ++ LF PKL+II  +PE+N R    ++T  R
Sbjct:    2 RVVPSDILQVKALINLLTYFKWSYISLLNSKGSYGEEGIKELQEHLKNTTDICTDEGLEIDNKEEAHKFDALALKLFKK-GKPKVILCFCQGDTVTKLLRSMTKLNMTKKGYLIIGTDGWADRTDILGTIENGRMELSEAALGSITIRLHSKPIPDFDDYFRTKTSSSTPGNPWFQEFWEKKFNC---------------------------HINKTKSDK-----------YPKTCTRKE-----SLFNMP-----YVQDSKLGFVVKSVMTIAWGLHNIYQKVCIVKNFTLEGCANFILR-NGKLLLDEMIDLKFSAYDNETVRFDSKGDPPGRYDIMNYQYGYNEKTNRTEYHYERIGSWKENHLVIEDHLIQWPKSEENERNNQTSIKSHCSDPCKFDQIRIFRERKKCCWTCKDCSENE-ITNKTFHNESCSSCKKGFRPNSDRSNCSEIPAIFLKWSDASVIVAIIFSIVGLIITVIIVGIFAKYNNTPVVKSCTRELMYVILVGVALSYLTTFPLVWKPTTFSCLLSRIMPGLSFSLIFGSLVTKTNRICRILSISKKKIIRRKGRFLTTTAQIVIVFLLNVVEIIIISVMIWHNFPKSKSDYSVAATVRLICNTESQDLFISMGFDAVLVCFCTWYAFKTRNLPENFNEAKFIGFTMYTTCIIWIGLVVIYLST----NLKEISLCFAMHFTATICIVFLFLPKLYIILFKPERNERSAFTTTTEIR 681          
BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Match: SMESG000033749.1 (SMESG000033749.1)

HSP 1 Score: 273.092 bits (697), Expect = 3.446e-85
Identity = 158/158 (100.00%), Postives = 158/158 (100.00%), Query Frame = 2
Query: 2804 MNSEYTPLPPPFNSQSHHLVVVSIQSHSPSINEPSTGGSVISNVHLXXXXXXXXXXXXLILKDSNFNEIIQSPFKTEXXXXXXXXXXNLMYLEDEFCVQRRSDCSDYFSSIKDIQEHLNSQIYVSENGHDSPFSQRRVKFPEKKTVILDFNQQNITSL 3277
            MNSEYTPLPPPFNSQSHHLVVVSIQSHSPSINEPSTGGSVISNVHLNNSFNKSQSQSKLILKDSNFNEIIQSPFKTEPSSLSSIPSPNLMYLEDEFCVQRRSDCSDYFSSIKDIQEHLNSQIYVSENGHDSPFSQRRVKFPEKKTVILDFNQQNITSL
Sbjct:    1 MNSEYTPLPPPFNSQSHHLVVVSIQSHSPSINEPSTGGSVISNVHLNNSFNKSQSQSKLILKDSNFNEIIQSPFKTEPSSLSSIPSPNLMYLEDEFCVQRRSDCSDYFSSIKDIQEHLNSQIYVSENGHDSPFSQRRVKFPEKKTVILDFNQQNITSL 158          
The following BLAST results are available for this feature:
BLAST of Metabotropic glutamate receptor vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRM30.000e+042.96glutamate metabotropic receptor 3 [Source:HGNC Sym... [more]
GRM20.000e+043.00glutamate metabotropic receptor 2 [Source:HGNC Sym... [more]
GRM80.000e+040.92glutamate metabotropic receptor 8 [Source:HGNC Sym... [more]
GRM80.000e+040.92glutamate metabotropic receptor 8 [Source:HGNC Sym... [more]
GRM80.000e+040.92glutamate metabotropic receptor 8 [Source:HGNC Sym... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mgl-10.000e+036.72Probable metabotropic glutamate receptor mgl-1 [S... [more]
mgl-10.000e+036.72Probable metabotropic glutamate receptor mgl-1 [S... [more]
mgl-10.000e+036.72Probable metabotropic glutamate receptor mgl-1 [S... [more]
mgl-12.992e-17336.29Probable metabotropic glutamate receptor mgl-1 [S... [more]
mgl-12.992e-17336.29Probable metabotropic glutamate receptor mgl-1 [S... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mGluR0.000e+044.83gene:FBgn0019985 transcript:FBtr0089184[more]
mGluR0.000e+044.83gene:FBgn0019985 transcript:FBtr0332858[more]
mtt9.156e-1939.29gene:FBgn0050361 transcript:FBtr0330608[more]
mtt9.331e-1939.29gene:FBgn0050361 transcript:FBtr0273325[more]
mtt0.000e+039.29gene:FBgn0050361 transcript:FBtr0273327[more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grm2a0.000e+043.02glutamate receptor, metabotropic 2a [Source:ZFIN;A... [more]
grm2a0.000e+043.02glutamate receptor, metabotropic 2a [Source:ZFIN;A... [more]
grm30.000e+041.68glutamate receptor, metabotropic 3 [Source:ZFIN;Ac... [more]
grm30.000e+041.68glutamate receptor, metabotropic 3 [Source:ZFIN;Ac... [more]
grm30.000e+041.68glutamate receptor, metabotropic 3 [Source:ZFIN;Ac... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRM80.000e+040.51glutamate receptor, metabotropic 8 [Source:NCBI ge... [more]
GRM80.000e+040.51glutamate receptor, metabotropic 8 [Source:NCBI ge... [more]
GRM20.000e+042.26glutamate receptor, metabotropic 2 [Source:NCBI ge... [more]
xylt10.000e+041.62xylosyltransferase I [Source:Xenbase;Acc:XB-GENE-9... [more]
xylt10.000e+041.57xylosyltransferase I [Source:Xenbase;Acc:XB-GENE-9... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Grm30.000e+042.25glutamate receptor, metabotropic 3 [Source:MGI Sym... [more]
Grm20.000e+042.79glutamate receptor, metabotropic 2 [Source:MGI Sym... [more]
Grm80.000e+040.63glutamate receptor, metabotropic 8 [Source:MGI Sym... [more]
Grm80.000e+040.63glutamate receptor, metabotropic 8 [Source:MGI Sym... [more]
Grm80.000e+040.63glutamate receptor, metabotropic 8 [Source:MGI Sym... [more]
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BLAST of Metabotropic glutamate receptor vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P91685|GRM_DROME0.000e+044.83Metabotropic glutamate receptor OS=Drosophila mela... [more]
sp|P31421|GRM2_RAT0.000e+042.91Metabotropic glutamate receptor 2 OS=Rattus norveg... [more]
sp|Q9QYS2|GRM3_MOUSE0.000e+042.25Metabotropic glutamate receptor 3 OS=Mus musculus ... [more]
sp|Q1ZZH1|GRM3_MACFA0.000e+043.07Metabotropic glutamate receptor 3 OS=Macaca fascic... [more]
sp|Q14832|GRM3_HUMAN0.000e+042.96Metabotropic glutamate receptor 3 OS=Homo sapiens ... [more]
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BLAST of Metabotropic glutamate receptor vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3PCU60.000e+052.58Metabotropic glutamate receptor OS=Schistocephalus... [more]
A0A5K4F4940.000e+050.28Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A5K4F3Y90.000e+050.28Uncharacterized protein OS=Schistosoma mansoni OX=... [more]
A0A158RER60.000e+051.57G_PROTEIN_RECEP_F3_4 domain-containing protein OS=... [more]
A0A4E0RXQ70.000e+049.94Metabotropic glutamate receptor OS=Fasciola hepati... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grm2a0.000e+042.63metabotropic glutamate receptor 2 [Source:NCBI gen... [more]
grm30.000e+041.85metabotropic glutamate receptor 3 [Source:NCBI gen... [more]
grm2b0.000e+042.68metabotropic glutamate receptor 2-like [Source:NCB... [more]
grm2b0.000e+041.75metabotropic glutamate receptor 2-like [Source:NCB... [more]
grm30.000e+041.08metabotropic glutamate receptor 3 [Source:NCBI gen... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grm30.000e+041.35glutamate receptor, metabotropic 3 [Source:ZFIN;Ac... [more]
ENSPMAT00000007590.10.000e+039.18pep scaffold:Pmarinus_7.0:GL478498:6932:63706:-1 g... [more]
ENSPMAT00000005888.11.797e-10042.54pep scaffold:Pmarinus_7.0:GL487952:898:2919:-1 gen... [more]
casr5.024e-9929.54calcium-sensing receptor [Source:ZFIN;Acc:ZDB-GENE... [more]
ENSPMAT00000008333.16.042e-8927.83pep scaffold:Pmarinus_7.0:GL477638:94752:105207:1 ... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Metabotropic glutamate receptor vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO317672.053e-16436.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352531.821e-15934.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO413159.024e-14435.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO486652.629e-14133.53Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476274.866e-13831.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Metabotropic glutamate receptor vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grm2a0.000e+044.12glutamate metabotropic receptor 2 [Source:NCBI gen... [more]
grm2a0.000e+044.12glutamate metabotropic receptor 2 [Source:NCBI gen... [more]
grm2b0.000e+042.81metabotropic glutamate receptor 2-like [Source:NCB... [more]
grm30.000e+042.06metabotropic glutamate receptor 3 [Source:NCBI gen... [more]
grm2b0.000e+042.81metabotropic glutamate receptor 2-like [Source:NCB... [more]
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BLAST of Metabotropic glutamate receptor vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000033752.10.000e+096.93SMESG000033752.1[more]
SMESG000033752.10.000e+096.39SMESG000033752.1[more]
SMESG000022915.17.244e-14433.98SMESG000022915.1[more]
SMESG000064049.12.689e-10831.29SMESG000064049.1[more]
SMESG000033749.13.446e-85100.00SMESG000033749.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025806 ID=SMED30025806|Name=Metabotropic glutamate receptor|organism=Schmidtea mediterranea sexual|type=transcript|length=3388bp
TTCATATCAAGATAGGAAACAGTATTTACTCGCCAATTGCATTTAATAGA
TTTCAAATTTTTTAATGTATTTTCGGATTTCTGGATGTAATCAGTTACCT
ATTGTTATTTATTATTCATTTTTTGTCACTGTGAATCTAATCGCTTCTGA
AATCGACAACAAATATCAGTCTGCAATCTACAATGGGGACATTATTCTCG
GCGGACTATTTCCAGTTCATGATTCCGAAACCGAGCTCTGCAAAAAAATC
AACCCCGACCGAGGAATCCAAAGATTGGAAGCTATGTTGTTCACGATTCA
GGAAATTAACAATCGGCCGGATATTTTACCAAATATTAACATTGGTGCTA
GAATTTTGGACACGTGCTCAAAAGACACTTATGCTCTTCAACAATCTCTA
GATTTTATCAAATCTTCATTGTCTGACAATAATGACGCTTCGGATTATTA
TTGTAAGGATAAAAGTGAAGTATTGAGACATACAAAAGCCACACAAAAAA
TTCGAACCGTCGTCGGAGGCTCATACTCTTCAGTTTCAATATTAGTTGCG
AATCTGTTGCGACTTTTCAGTATTCCACAAATCAGTTACGCATCAACAAG
TGCTCTGTTAAGTGAGAAAAAAAATCATCCCATTTTCGCAAGAACTCTTC
CGTCGGATCAGCAACAGGCTAAAGCCATGGCAGAATTGGTAGCTTCATTC
AATTGGACCTATGTTTCTACAGTTCGCAGCAGTGGAGATTATGGAGACAG
CGGAATTGATGCGTTTTGGAAAGAAAGTAAAAAACTTGGAGTTTGTATTG
CTGCAAAAGAAATGATAAAACCGAATCCTTTGCACTCGGATTTATTAGCT
ATTGTCAAAACTCTTTATCAGGAATTCAGTAAAACAAGAGTAGTCGTTTT
ATTTACTAGACTAGATCACACAAAGCTTTTATTAAACGCTGTGAAAATAA
TGAATTATTCTAATTACTTTTTATGGATAGCCAGTGATGGTTGGGGCCAA
GAAAATGGGCCCGTAACAAACAACAGTAACGTAGCAAATGGAGCGATTAC
ATTCGAAGTGAAAACCGTGGAAATCAAAAACTTCACCACGTATTTTCATC
AGCTTACATACAACAGAAATTCCAACAATCCGTGGTTTGATGAATATTGG
GAGGAGTTGTTTGACTGCATTCCAATTAAACAAAAAATGCGCGTTTCTCG
ATCATCTGTTAAGTCATTGATGAGTGGAAAAGAAAGCTATTACTACTTTC
ACACAAATTTCACCGATGTGAACAAACAAAACCAAAACTCATTTCACAGA
GATTACAGATTTCCACGGTCGAATTCCGTGAAATCGAGAAAACAGTTGTG
CACAATGTTTAATTTCTCAAGCAAACTGAAGAACTTCAAACAGGAATCTA
AAATCCAGTCGGTCTATGATGCCGTATACGCAGTAGCCTATACTTTGGAT
AGGTTTCAATCCAAACTATGCAAGCCTTTTGTATTGGAAAAATGCGTGAA
AGCTTTAAATAATATTGATGGAATGGTATTTTATAAAGATCTTATTAACA
ATAGTTTTACGGACTCATATGGAAACCTTGTATCGTTTGATAGCAATGGT
GACAGCGTTGGACAGTACAACATTTACAATTATATACGAAACAAAAAAAC
TGGAAAATATTACTATAAAAATATAGGTGAATTTCGACATGATGGGCTTT
TCTTAAATTCGGAGGTAACTTGGCCAGGCGAAGAAAAAGAAATACCGCGA
TCCATATGCAGTGAAGATTGCCCTGTCGGACAAATTCGAATTTACAGCAA
AGAAAGCAAATGCTGCTGGGGGTGCAGTTTATGTAAGAGTAATGAATACG
TTGTGAACATGACAAAATGCGAAATGTGCGCTGAAGGAGAATGGCCTTAC
CAGAATAGAACTGGTTGCTATCTTTTAACTGTTCACTACATGAAACTCAG
TGGTTGGTTAGCTATTATACCTATGATTCTCAGTTTTCTCGGCACTGCAA
CTACAACATCTGTAATGGGTGTTTTCTATTATTATAAAAATACTCCAATT
GTTAGAGCTTCGGGGCGTGAGCTGTCGTTTTTAATTCTCTCAGGATGCTT
AGTTTGTTATTTGGTGTCATTTGTTTTTCTCCTCAAACCGACTCCTTATT
CGTGTGCCATTCAAAGGATTTTACTGGGACTTGGCTTTGCAGTTATGTAT
GCTTCACTGTTAACTAAAACTAATAGAATAGCCAGAATATTTGAATCTGC
TCAAAAAACCGCTAAGAGACCTCCGTGCATTTCTCCAAAATCTCAATTGA
TGATCTGTGCAGTTTTAATTAGTGTTCAGCTCCTCTCAAATGCAATCTGG
CTGTTCTTTTCTCCGCCGGGAATTCGCTACGATCGCAAAAAACCCGAATT
CCCAGTGTTGAAATGTAAAATTGAAACAAAAACGTTTTTAGTTTCCCTTG
TGTACAATATGTTACTCATCTCAGTTTGCACGTATTATGCAATTAAAACA
AGAAAAATCCCAGAAAATTTCAACGAATCAAAGTTTATTGGTTTTACCAT
GTATACAACGTGCGTTATATGGTTAGCATTTATTACAATATACTTTGGAA
CTCTCCATTCCTTTGAGGTGCAAATTTCCACTCTTGGAATTTCTGTCAGT
CTCAGTGCTTGGGTCACATTAATTTGTCTATTTTTTCCAAAATTGCACAT
AATATTTTTACAGCCGGAGAAGAATGTTAGAAAACTAACCATGAGCAGTA
CAACCTACAGAAAACCAACCAACTCTTCAGGTTCATTTGCTAATCATCGT
GAAATGAATTCAGAATACACTCCATTGCCTCCACCGTTTAACTCACAGTC
GCATCACTTGGTTGTCGTATCAATACAGTCACATTCCCCATCAATCAACG
AGCCTTCGACTGGTGGCTCAGTAATCAGTAACGTCCATCTCAACAATTCA
TTTAATAAATCACAATCTCAAAGCAAATTAATCCTCAAAGACTCCAATTT
TAATGAAATTATTCAAAGTCCTTTTAAAACCGAACCTTCCTCACTCTCAT
CTATTCCTAGTCCAAATTTAATGTATTTAGAAGATGAATTTTGTGTCCAA
AGACGCAGTGATTGTTCAGATTATTTTTCATCAATCAAAGACATTCAAGA
ACATCTCAATTCACAGATTTACGTGAGCGAAAATGGACATGACTCTCCGT
TTAGTCAACGACGCGTCAAATTCCCAGAGAAAAAGACAGTTATTTTAGAT
TTCAATCAGCAAAATATTACATCATTATAAAAAAGACTTTTTTTATATAA
ATATTGTTAAATCTGAGCAAGATTTGTTCATGGTTTTAGAATGCTCATTT
AAATTGTAAATGGTTATCAATGATAAACTTTAAAAAAT
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protein sequence of SMED30025806-orf-1

>SMED30025806-orf-1 ID=SMED30025806-orf-1|Name=SMED30025806-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1072bp
MYFRISGCNQLPIVIYYSFFVTVNLIASEIDNKYQSAIYNGDIILGGLFP
VHDSETELCKKINPDRGIQRLEAMLFTIQEINNRPDILPNINIGARILDT
CSKDTYALQQSLDFIKSSLSDNNDASDYYCKDKSEVLRHTKATQKIRTVV
GGSYSSVSILVANLLRLFSIPQISYASTSALLSEKKNHPIFARTLPSDQQ
QAKAMAELVASFNWTYVSTVRSSGDYGDSGIDAFWKESKKLGVCIAAKEM
IKPNPLHSDLLAIVKTLYQEFSKTRVVVLFTRLDHTKLLLNAVKIMNYSN
YFLWIASDGWGQENGPVTNNSNVANGAITFEVKTVEIKNFTTYFHQLTYN
RNSNNPWFDEYWEELFDCIPIKQKMRVSRSSVKSLMSGKESYYYFHTNFT
DVNKQNQNSFHRDYRFPRSNSVKSRKQLCTMFNFSSKLKNFKQESKIQSV
YDAVYAVAYTLDRFQSKLCKPFVLEKCVKALNNIDGMVFYKDLINNSFTD
SYGNLVSFDSNGDSVGQYNIYNYIRNKKTGKYYYKNIGEFRHDGLFLNSE
VTWPGEEKEIPRSICSEDCPVGQIRIYSKESKCCWGCSLCKSNEYVVNMT
KCEMCAEGEWPYQNRTGCYLLTVHYMKLSGWLAIIPMILSFLGTATTTSV
MGVFYYYKNTPIVRASGRELSFLILSGCLVCYLVSFVFLLKPTPYSCAIQ
RILLGLGFAVMYASLLTKTNRIARIFESAQKTAKRPPCISPKSQLMICAV
LISVQLLSNAIWLFFSPPGIRYDRKKPEFPVLKCKIETKTFLVSLVYNML
LISVCTYYAIKTRKIPENFNESKFIGFTMYTTCVIWLAFITIYFGTLHSF
EVQISTLGISVSLSAWVTLICLFFPKLHIIFLQPEKNVRKLTMSSTTYRK
PTNSSGSFANHREMNSEYTPLPPPFNSQSHHLVVVSIQSHSPSINEPSTG
GSVISNVHLNNSFNKSQSQSKLILKDSNFNEIIQSPFKTEPSSLSSIPSP
NLMYLEDEFCVQRRSDCSDYFSSIKDIQEHLNSQIYVSENGHDSPFSQRR
VKFPEKKTVILDFNQQNITSL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR038550GPCR_3_9-Cys_sf
IPR000162GPCR_3_mtglu_rcpt
IPR000337GPCR_3
IPR001828ANF_lig-bd_rcpt
IPR017978GPCR_3_C
IPR011500GPCR_3_9-Cys_dom
IPR017979GPCR_3_CS
IPR028082Peripla_BP_I
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005886plasma membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007165signal transduction
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004871signal transducer activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000162GPCR, family 3, metabotropic glutamate receptorPRINTSPR00593MTABOTROPICRcoord: 271..285
score: 51.23
coord: 12..23
score: 55.26
coord: 426..440
score: 59.3
IPR001828Receptor, ligand binding regionPFAMPF01094ANF_receptorcoord: 9..96
e-value: 1.9E-10
score: 40.4
IPR038550GPCR, family 3, nine cysteines domain superfamilyGENE3DG3DSA:2.10.50.30coord: 129..203
e-value: 4.2E-20
score: 73.3
NoneNo IPR availableGENE3DG3DSA:3.40.50.2300coord: 89..110
e-value: 1.0E-18
score: 69.2
NoneNo IPR availableGENE3DG3DSA:3.40.50.2300coord: 6..88
e-value: 1.0E-18
score: 69.2
NoneNo IPR availablePANTHERPTHR24060:SF155MANGETOUT, ISOFORM Gcoord: 9..469
NoneNo IPR availablePANTHERPTHR24060METABOTROPIC GLUTAMATE RECEPTORcoord: 9..469
NoneNo IPR availableCDDcd159347tmC_mGluRs_group2_3coord: 201..452
e-value: 3.74139E-139
score: 404.302
NoneNo IPR availableTMHMMTMhelixcoord: 395..417
NoneNo IPR availableTMHMMTMhelixcoord: 269..286
NoneNo IPR availableTMHMMTMhelixcoord: 361..380
NoneNo IPR availableTMHMMTMhelixcoord: 429..451
NoneNo IPR availableTMHMMTMhelixcoord: 240..259
NoneNo IPR availableTMHMMTMhelixcoord: 205..227
IPR017978GPCR family 3, C-terminalPFAMPF000037tm_3coord: 216..449
e-value: 6.8E-64
score: 215.8
IPR017978GPCR family 3, C-terminalPROSITEPS50259G_PROTEIN_RECEP_F3_4coord: 202..466
score: 64.209
IPR011500GPCR, family 3, nine cysteines domainPFAMPF07562NCD3Gcoord: 131..181
e-value: 9.4E-14
score: 51.1
IPR017979GPCR, family 3, conserved sitePROSITEPS00981G_PROTEIN_RECEP_F3_3coord: 389..399
IPR028082Periplasmic binding protein-like ISUPERFAMILYSSF53822Periplasmic binding protein-like Icoord: 10..125