SOXB1-1

Overview


Name	SOXB1-1
Smed ID	SMED30025778
Length (bp)	1738

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of SOXB1-1 (SMED30025778) t-SNE clustered cells

Violin plots show distribution of expression levels for SOXB1-1 (SMED30025778) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SOXB1-1 (SMED30025778) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SOXB1-1 (SMED30025778) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025778

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30025778	SMESG000011244.1	SmedASXL_010283	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
X1 cell	SMED30025778	SMESG000011244.1	SmedASXL_010283	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30025778	SMESG000011244.1	SmedASXL_010283	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
head region	SMED30025778	SMESG000011244.1	dd_Smed_v6_13215_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30025778	SMESG000011244.1	Smed-soxB	smed_ncbi_20200123	PMID:22884275 Lapan et al., 2012
eye	SMED30025778	SMESG000011244.1	SMED30025778	smed_20140614	PMID:25254346 Scimone et al., 2014
central nervous system	SMED30025778	SMESG000011244.1	SMED30025778	smed_20140614	PMID:25254346 Scimone et al., 2014
gamma neoblast	SMED30025778	SMESG000011244.1	SMED30025778	smed_20140614	PMID:25017721 van Wolfswinkel et al., 2014
sigma neoblast	SMED30025778	SMESG000011244.1	SMED30025778	smed_20140614	PMID:25017721 van Wolfswinkel et al., 2014

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX2 (SRY-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11195])

HSP 1 Score: 151.754 bits (382), Expect = 9.386e-41
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   39 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 125

[Close]

BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX14 (SRY-box transcription factor 14 [Source:HGNC Symbol;Acc:HGNC:11193])

HSP 1 Score: 149.058 bits (375), Expect = 1.382e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX21 (SRY-box transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11197])

HSP 1 Score: 148.673 bits (374), Expect = 4.667e-40
Identity = 73/109 (66.97%), Postives = 82/109 (75.23%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF-------LGSAAMANVTAL 1142
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF       LG  A A   AL
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPAL 111

[Close]

BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX1 (SRY-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11189])

HSP 1 Score: 143.665 bits (361), Expect = 3.805e-37
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK +SE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 124

[Close]

BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX15 (SRY-box transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11196])

HSP 1 Score: 134.806 bits (338), Expect = 3.896e-36
Identity = 59/80 (73.75%), Postives = 69/80 (86.25%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA 1085
            ++VKRPMNAFMVWS  QRR+MAQ NPKMHNSEISKRLG  WK L E++K+PF++EAKRLRA H+  YPDYKYRPRRK K+
Sbjct:   47 EKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS 126

[Close]

BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-3 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q20201])

HSP 1 Score: 150.214 bits (378), Expect = 6.961e-42
Identity = 68/96 (70.83%), Postives = 81/96 (84.38%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV 1133
            D VKRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+ + +++   + AM  +
Sbjct:   46 DHVKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKQLSEQEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKSSNLKQQPRLNIAMPTI 141

[Close]

BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-2 (Transcription factor sox-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21305])

HSP 1 Score: 151.754 bits (382), Expect = 1.286e-41
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141

[Close]

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141

[Close]

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141

[Close]

BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-4 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q17922])

HSP 1 Score: 103.219 bits (256), Expect = 1.573e-24
Identity = 41/82 (50.00%), Postives = 59/82 (71.95%), Query Frame = 3

Query:  840 KDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA 1085
            ++ R+KRPMNAFMVWS+ +R+++A    K HNS+ISK LG  W+ + E +K PF++ AK+LR  H   +PDY YRPRR+ + 
Sbjct:  117 REPRIKRPMNAFMVWSQQRRQQIAATGQKFHNSDISKMLGAEWRKMEEHEKVPFVERAKQLREEHFNAHPDYVYRPRRRKRV 198

[Close]

BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21a (gene:FBgn0036411 transcript:FBtr0330178)

HSP 1 Score: 149.058 bits (375), Expect = 2.588e-39
Identity = 65/83 (78.31%), Postives = 73/83 (87.95%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            D +KRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK L+E  K+PFIDEAKRLRA HM ++PDYKYRPRRK K ++K
Sbjct:  119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNK 201

[Close]

BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21a (gene:FBgn0036411 transcript:FBtr0075748)

HSP 1 Score: 148.673 bits (374), Expect = 2.730e-39
Identity = 65/83 (78.31%), Postives = 73/83 (87.95%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            D +KRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK L+E  K+PFIDEAKRLRA HM ++PDYKYRPRRK K ++K
Sbjct:  119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNK 201

[Close]

BLAST of SOXB1-1 vs. Ensembl Fly
Match: SoxN (gene:FBgn0029123 transcript:FBtr0079733)

HSP 1 Score: 149.828 bits (377), Expect = 1.941e-38
Identity = 64/76 (84.21%), Postives = 70/76 (92.11%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MA DNPKMHNSEISKRLG  WK+LSE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:  177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRR 252

[Close]

BLAST of SOXB1-1 vs. Ensembl Fly
Match: SoxN (gene:FBgn0029123 transcript:FBtr0330210)

HSP 1 Score: 150.599 bits (379), Expect = 3.986e-38
Identity = 64/76 (84.21%), Postives = 70/76 (92.11%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MA DNPKMHNSEISKRLG  WK+LSE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:  177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRR 252

[Close]

BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21b (gene:FBgn0042630 transcript:FBtr0075747)

HSP 1 Score: 146.747 bits (369), Expect = 2.204e-37
Identity = 63/84 (75.00%), Postives = 75/84 (89.29%), Query Frame = 3

Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            ++ +KRPMNAFMVWSR QRR++AQDNPKMHNSEISKRLG  WK L+EE+K+PFIDEAKRLRA HM ++PDYKYRPRRK KA+ +
Sbjct:  245 EEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRR 328

[Close]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 151.369 bits (381), Expect = 7.105e-41
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DR+KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   36 DRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 122

[Close]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox14 (SRY-box transcription factor 14 [Source:NCBI gene;Acc:557661])

HSP 1 Score: 148.288 bits (373), Expect = 1.328e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPADHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox21b (SRY-box transcription factor 21b [Source:NCBI gene;Acc:406246])

HSP 1 Score: 147.902 bits (372), Expect = 2.162e-40
Identity = 67/90 (74.44%), Postives = 76/90 (84.44%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPMDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLMKKDKF 92

[Close]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox19b (SRY-box transcription factor 19b [Source:NCBI gene;Acc:64812])

HSP 1 Score: 149.058 bits (375), Expect = 3.118e-40
Identity = 69/108 (63.89%), Postives = 85/108 (78.70%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMG 1169
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L++ +K+PFIDEAKRLRA HM +YPDYKY+PRRK KA+ K+   +G   +A    L+  + +  G
Sbjct:   51 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNPVGKYPLAAGNLLASAVAQGQG 158

[Close]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox21a (SRY-box transcription factor 21a [Source:NCBI gene;Acc:30543])

HSP 1 Score: 144.05 bits (362), Expect = 5.946e-39
Identity = 66/90 (73.33%), Postives = 76/90 (84.44%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MA DNPKMHNSEISKRLGG WK LS+ +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ ++
Sbjct:    3 KPMDHVKRPMNAFMVWSRVQRRKMALDNPKMHNSEISKRLGGEWKLLSDSEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKPKNLIKKDRY 92

[Close]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox2 (SRY-box 2 [Source:NCBI gene;Acc:407873])

HSP 1 Score: 153.295 bits (386), Expect = 1.932e-41
Identity = 76/138 (55.07%), Postives = 94/138 (68.12%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMGY-----FNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G         ++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGASLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172

[Close]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: spag16 (sperm associated antigen 16 [Source:Xenbase;Acc:XB-GENE-949128])

HSP 1 Score: 147.902 bits (372), Expect = 2.982e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPVDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: gsr (glutathione reductase [Source:Xenbase;Acc:XB-GENE-997099])

HSP 1 Score: 145.976 bits (367), Expect = 3.585e-39
Identity = 67/90 (74.44%), Postives = 76/90 (84.44%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKF 92

[Close]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox3 (SRY-box 3 [Source:NCBI gene;Acc:493228])

HSP 1 Score: 144.436 bits (363), Expect = 2.797e-38
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LS+ +K+PFIDEAKRLRA HM +YPDYKYRPRR
Sbjct:   38 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVHMKEYPDYKYRPRR 113

[Close]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox17b.3 (SRY-box 17 alpha [Source:NCBI gene;Acc:395066])

HSP 1 Score: 124.79 bits (312), Expect = 1.209e-30
Identity = 51/94 (54.26%), Postives = 72/94 (76.60%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSA 1118
            K + R++RPMNAFMVW++ +R+R+AQ NP +HN+E+SK LG  WK+L+   K+PF+ EA+RLR  H+  YPDYKYRPRRK +   +++ FL SA
Sbjct:   56 KAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLASKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVKREEEGFLPSA 149

[Close]

BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox2 (SRY (sex determining region Y)-box 2 [Source:MGI Symbol;Acc:MGI:98364])

HSP 1 Score: 152.14 bits (383), Expect = 5.638e-41
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   41 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 127

[Close]

BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox21 (SRY (sex determining region Y)-box 21 [Source:MGI Symbol;Acc:MGI:2654070])

HSP 1 Score: 150.214 bits (378), Expect = 8.756e-41
Identity = 74/109 (67.89%), Postives = 83/109 (76.15%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF-------LGSAAMANVTAL 1142
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF       LGS A A   AL
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGSVADAEHPAL 111

[Close]

BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox14 (SRY (sex determining region Y)-box 14 [Source:MGI Symbol;Acc:MGI:98362])

HSP 1 Score: 149.058 bits (375), Expect = 9.204e-41
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox14 (SRY (sex determining region Y)-box 14 [Source:MGI Symbol;Acc:MGI:98362])

HSP 1 Score: 139.813 bits (351), Expect = 2.912e-38
Identity = 71/123 (57.72%), Postives = 87/123 (70.73%), Query Frame = 3

Query:  861 PMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLA 1229
            PMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+     S+A+  +  + H L      +   AS  GY    + SL+
Sbjct:    2 PMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKD---SSSAIQKMGEVPHTLATSALPY---ASTLGYQNGAFGSLS 118

[Close]

BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox1 (SRY (sex determining region Y)-box 1 [Source:MGI Symbol;Acc:MGI:98357])

HSP 1 Score: 143.665 bits (361), Expect = 2.462e-37
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK +SE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 124

[Close]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|O42569|SOX2_XENLA (Transcription factor Sox-2 OS=Xenopus laevis OX=8355 GN=sox2 PE=1 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 2.105e-41
Identity = 77/138 (55.80%), Postives = 95/138 (68.84%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMG-----YFNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G        A++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANAMTSGVGGSLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172

[Close]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|P48430|SOX2_CHICK (Transcription factor SOX-2 OS=Gallus gallus OX=9031 GN=SOX2 PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 3.668e-41
Identity = 78/140 (55.71%), Postives = 94/140 (67.14%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--------GSAAMANVTALSHQLGREMG-YFNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+         G+  M     +   LG  +    +S A  NG+   GY  +   +
Sbjct:   37 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGTNTMTTGVGVGATLGAGVNQRMDSYAHMNGWTNGGYGMMQEQL 176

[Close]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|Q6NVN0|SOX2_XENTR (Transcription factor Sox-2 OS=Xenopus tropicalis OX=8364 GN=sox2 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.024e-40
Identity = 76/138 (55.07%), Postives = 94/138 (68.12%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMGY-----FNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G         ++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGASLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172

[Close]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|Q21305|SOX2_CAEEL (Transcription factor sox-2 OS=Caenorhabditis elegans OX=6239 GN=sox-2 PE=1 SV=2)

HSP 1 Score: 151.754 bits (382), Expect = 1.636e-40
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141

[Close]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|P48432|SOX2_MOUSE (Transcription factor SOX-2 OS=Mus musculus OX=10090 GN=Sox2 PE=1 SV=2)

HSP 1 Score: 152.14 bits (383), Expect = 3.601e-40
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   41 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 127

[Close]

BLAST of SOXB1-1 vs. TrEMBL
Match: A0A0A7M699 (SOXB1-1 (Fragment) OS=Schmidtea polychroa OX=50054 GN=soxb1-1 PE=2 SV=1)

HSP 1 Score: 957.977 bits (2475), Expect = 0.000e+0
Identity = 548/553 (99.10%), Postives = 549/553 (99.28%), Query Frame = 3

Query:   42 VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVE NHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITS+SQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF GSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHS YPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEG QPL
Sbjct:    1 VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVETNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSNSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFXGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSXYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGAQPL 553

[Close]

BLAST of SOXB1-1 vs. TrEMBL
Match: J7FQ58 (SoxB OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 941.799 bits (2433), Expect = 0.000e+0
Identity = 538/539 (99.81%), Postives = 539/539 (100.00%), Query Frame = 3

Query:   84 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSS+SSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSTSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 539

[Close]

BLAST of SOXB1-1 vs. TrEMBL
Match: A0A2H1CRL6 (HMG box OS=Fasciola hepatica OX=6192 GN=D915_02355 PE=4 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 1.207e-46
Identity = 92/142 (64.79%), Postives = 105/142 (73.94%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLASGYASLAHSIDSTPYSS 1259
            KK+DRVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L E +KKPFIDEAKRLRANHM QYPDYKYRPRRKHK +D+QKK  G     N T + + +G  + G    G +G G LA G  ++    D+   SS
Sbjct:   30 KKEDRVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGSMWKGLGETEKKPFIDEAKRLRANHMAQYPDYKYRPRRKHKPLDRQKKTTG----LNATVMGNYMGSSLAGSGLVGRAGVG-LAPGSRTMTSLFDALGSSS 166

[Close]

BLAST of SOXB1-1 vs. TrEMBL
Match: A0A183SQT9 (HMG box domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6587 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 6.211e-46
Identity = 80/102 (78.43%), Postives = 92/102 (90.20%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTAL 1142
            K+D+RVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L+E DKKPFIDEAKRLRANHM+QYPDYKYRPRR+H+ ++KQKK + + A A V+ L
Sbjct:    5 KRDERVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGTMWKALNESDKKPFIDEAKRLRANHMSQYPDYKYRPRRRHRPLEKQKKAVAAMAAATVSGL 106

[Close]

BLAST of SOXB1-1 vs. TrEMBL
Match: A0A504YLM5 (Transcription factor SOX-2 OS=Fasciola gigantica OX=46835 GN=FGIG_02653 PE=4 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 7.827e-46
Identity = 92/142 (64.79%), Postives = 105/142 (73.94%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLASGYASLAHSIDSTPYSS 1259
            KK+DRVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L E +KKPFIDEAKRLRANHM QYPDYKYRPRRKHK +D+QKK  G     N T + + +G  + G    G +G G LA G  ++    D+   SS
Sbjct:  410 KKEDRVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGSMWKGLGETEKKPFIDEAKRLRANHMAQYPDYKYRPRRKHKPLDRQKKTTG----LNATVMGNYMGSSLAGTGLVGRAGVG-LAPGSRTMTSLFDALGSSS 546

[Close]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox19b (transcription factor Sox-19b [Source:NCBI gene;Acc:103045346])

HSP 1 Score: 150.214 bits (378), Expect = 7.682e-41
Identity = 84/151 (55.63%), Postives = 97/151 (64.24%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLAS-----GYASLAHSID--STPYSSHMYYN 1274
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L++ +K+PFIDEAKRLRA HM +YPDYKY+PRRK K + K+    G   +   TA    L   M GY    A G GY A      GY    H  D     Y +H Y N
Sbjct:   52 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKPLLKKDAPPGKYPL--TTAQGQALSPRMDGY--GWAPGGGYTAMQSDALGYTQQLHRYDLSGLQYPTHTYMN 198

[Close]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 149.058 bits (375), Expect = 1.082e-40
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   37 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 123

[Close]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: ENSAMXT00000004288.2 (pep primary_assembly:Astyanax_mexicanus-2.0:13:15067225:15068019:-1 gene:ENSAMXG00000004192.2 transcript:ENSAMXT00000004288.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.517 bits (371), Expect = 1.697e-40
Identity = 64/91 (70.33%), Postives = 79/91 (86.81%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+++++
Sbjct:    3 KPVDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKERYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox21b (SRY-box transcription factor 21b [Source:NCBI gene;Acc:406246])

HSP 1 Score: 147.132 bits (370), Expect = 2.344e-40
Identity = 78/143 (54.55%), Postives = 96/143 (67.13%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQK---KFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYS 1256
            K  + VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K++    F     +A   A + ++G  +G F S A    +L         SI + PYS
Sbjct:    3 KSGEHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLLKKEGKFAFPVPYGLAEHEA-ALKVGAGLGSFPSAALSEVFLNP-------SIPAHPYS 137

[Close]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: ENSAMXT00000026650.2 (transcription factor Sox-14-like [Source:NCBI gene;Acc:103039590])

HSP 1 Score: 144.821 bits (364), Expect = 1.314e-39
Identity = 65/90 (72.22%), Postives = 74/90 (82.22%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSRGQRRRMA +NPKMHNSEISKRLG  WK LSE  K+P+IDEAKRLRA HM ++P+YKYRPRRK K + +  +F
Sbjct:    3 KSVDHVKRPMNAFMVWSRGQRRRMAMENPKMHNSEISKRLGAEWKLLSEAQKRPYIDEAKRLRAQHMKEHPNYKYRPRRKSKGLLRNDRF 92

[Close]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox1b (SRY-box transcription factor 1b [Source:NCBI gene;Acc:562710])

HSP 1 Score: 149.443 bits (376), Expect = 5.328e-40
Identity = 63/77 (81.82%), Postives = 71/77 (92.21%), Query Frame = 3

Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            +DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   56 NDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 132

[Close]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 117.857 bits (294), Expect = 4.768e-29
Identity = 53/88 (60.23%), Postives = 67/88 (76.14%), Query Frame = 3

Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGS 1115
            +KRPMNAFMVWS+ +RR++ + +P MHN+EISKRLG  WK L E +K PFI EA+RLR  HM  YPDYKYRPR+K K   +Q++  GS
Sbjct:   62 IKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGRRWKQLKESEKVPFIREAERLRLKHMADYPDYKYRPRKKAKLAQQQQQQQGS 149

[Close]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox12 (SRY-box transcription factor 12 [Source:ZFIN;Acc:ZDB-GENE-040724-33])

HSP 1 Score: 112.079 bits (279), Expect = 4.385e-27
Identity = 47/77 (61.04%), Postives = 61/77 (79.22%), Query Frame = 3

Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHK 1082
            +KRPMNAFMVWS+ +RR++  ++P +HN+EISKRLG  WK L + +K PF+ EA+RLR  HM  YPDYKYRPR+K K
Sbjct:   60 IKRPMNAFMVWSQIERRKIMMESPDVHNAEISKRLGRRWKQLKDCEKVPFMREAERLRLKHMADYPDYKYRPRKKAK 136

[Close]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010223.1 (pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 gene:ENSPMAG00000009255.1 transcript:ENSPMAT00000010223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 8.198e-27
Identity = 43/80 (53.75%), Postives = 65/80 (81.25%), Query Frame = 3

Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHK 1082
            + R+ RPMNAFMVW++ +RRR+A+ NP +HN+E+SK LG  W+ L+ E ++P ++EA+RLR  H++++PDYKYRPRRK +
Sbjct:    3 EPRIPRPMNAFMVWAKDERRRLAKQNPDLHNAELSKMLGKSWRALTPESRRPCVEEAERLRLLHLSEHPDYKYRPRRKKQ 82

[Close]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox10 (SRY-box transcription factor 10 [Source:ZFIN;Acc:ZDB-GENE-011207-1])

HSP 1 Score: 105.145 bits (261), Expect = 3.714e-25
Identity = 41/75 (54.67%), Postives = 61/75 (81.33%), Query Frame = 3

Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRK 1076
            VKRPMNAFMVW++  RR+++   P++HN+E+SK LG +W+ L+E +K+PF++EA+RLR  H   +PDYKY+PRR+
Sbjct:  112 VKRPMNAFMVWAQAARRKLSDQYPQLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRMQHKKDHPDYKYQPRRR 186

[Close]

BLAST of SOXB1-1 vs. Ensembl Yeast
Match: ROX1 (Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269])

HSP 1 Score: 58.151 bits (139), Expect = 1.319e-9
Identity = 30/80 (37.50%), Postives = 46/80 (57.50%), Query Frame = 3

Query:  849 RVKRPMNAFMVWSRGQRRRM-----AQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            ++ RP NAF+++ +   R +     AQ     HNS ISK +G  WK L  EDK  + + A++ +  H  +YP+YKY+P R
Sbjct:    9 KIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVR 88

[Close]

BLAST of SOXB1-1 vs. Ensembl Yeast
Match: ABF2 (Mitochondrial DNA-binding protein; involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation; ABF2 has a paralog, IXR1, that arose from the whole genome duplication; human homolog TFAM can complement yeast abf2 mutant, rescuing the loss-of-mitochondrial DNA phenotype in a yeast abf2 strain [Source:SGD;Acc:S000004676])

HSP 1 Score: 45.4394 bits (106), Expect = 4.545e-6
Identity = 20/56 (35.71%), Postives = 35/56 (62.50%), Query Frame = 3

Query:  855 KRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRL 1022
            KRP +A+ ++ +  R +  ++NP +  +EISK  G  W+NL  + K+ +I E K+L
Sbjct:   44 KRPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKL 99

[Close]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO40934 (Predicted protein; Sox family protein B1 [Source:UniProtKB/TrEMBL;Acc:Q3S381])

HSP 1 Score: 147.132 bits (370), Expect = 1.801e-39
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            DRVKRPMNAFMVWSR +RR+MAQDNPKMHNSEISKRLG  WK LSE++K+P+IDEA+RLRA HM ++PDYKYRPRRK K + K+
Sbjct:   31 DRVKRPMNAFMVWSRERRRKMAQDNPKMHNSEISKRLGSEWKLLSEQEKRPYIDEARRLRAVHMKEHPDYKYRPRRKSKTLLKK 114

[Close]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO32666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUF3])

HSP 1 Score: 139.043 bits (349), Expect = 1.095e-37
Identity = 60/87 (68.97%), Postives = 76/87 (87.36%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K  + VKRPMNAFMVWSR +RR++AQ+NPKMHNSEISKRLG  WK L+++DKKPF++EAK+LRA HM ++PDYKYRPRRK K++ K+
Sbjct:    5 KPVEHVKRPMNAFMVWSREERRKIAQENPKMHNSEISKRLGSEWKQLADDDKKPFVEEAKKLRAQHMKEHPDYKYRPRRKPKSLLKK 91

[Close]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO44142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWK8])

HSP 1 Score: 123.635 bits (309), Expect = 4.618e-31
Identity = 60/120 (50.00%), Postives = 83/120 (69.17%), Query Frame = 3

Query:  837 KKDD---RVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV--TALSHQLGRE-MGYFN 1178
            +KDD   R+KRPMNAFMVW++ +RRR+A  NP++HN+E+SK LG  W+ L+   K+PF+DEA+RLR  HM  YP+YKYRPRR+  +    K+  G+AA + V  TA     G+E +  FN
Sbjct:   65 EKDDETERIKRPMNAFMVWAQVERRRLADANPELHNAELSKMLGLTWRALNSTQKRPFVDEAERLRLQHMQDYPNYKYRPRRRKHSKRAAKRSTGAAAGSKVNGTACQKSSGQETVSRFN 184

[Close]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO47688 (Predicted protein; Sox family protein 2 [Source:UniProtKB/TrEMBL;Acc:Q3S383])

HSP 1 Score: 112.464 bits (280), Expect = 2.779e-28
Identity = 50/88 (56.82%), Postives = 68/88 (77.27%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQK 1100
            K  D +KRPMNA+MVWSR +RRR+A++ P+M NSEISKRLG  W +L+ ++K+P+++EAKRLR  H   +PDYKY+P+RK K   K K
Sbjct:    3 KPGDHIKRPMNAYMVWSRKERRRIAEECPRMLNSEISKRLGLEWNSLTLDEKQPYVEEAKRLRELHKKDHPDYKYQPKRKPKTSPKLK 90

[Close]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO39449 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9V3])

HSP 1 Score: 107.071 bits (266), Expect = 4.212e-28
Identity = 48/78 (61.54%), Postives = 58/78 (74.36%), Query Frame = 3

Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRK 1076
            D  +KRPMNAFMVWSR +RR++A   P M N EISK LG  W  LSEE+K+PF+ EAKRLR  H  +YPDY Y+PRR+
Sbjct:    6 DQHIKRPMNAFMVWSRTERRKLALKYPNMLNCEISKLLGAEWSRLSEEEKRPFVTEAKRLRTIHNQKYPDYSYKPRRR 83

[Close]

BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox14 (SRY-box transcription factor 14 [Source:NCBI gene;Acc:100304454])

HSP 1 Score: 148.288 bits (373), Expect = 1.119e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPADHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93

[Close]

BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 148.673 bits (374), Expect = 1.125e-40
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   38 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 124

[Close]

BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox21 (SRY-box transcription factor 21 [Source:NCBI gene;Acc:100304456])

HSP 1 Score: 147.902 bits (372), Expect = 2.001e-40
Identity = 68/90 (75.56%), Postives = 76/90 (84.44%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPMDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLMKKDKF 92

[Close]

BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox19b (transcription factor Sox-19a [Source:NCBI gene;Acc:110017107])

HSP 1 Score: 147.132 bits (370), Expect = 1.771e-39
Identity = 65/84 (77.38%), Postives = 75/84 (89.29%), Query Frame = 3

Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LS+ +K+PFIDEAKRLRA HM +YPDYKY+PRRK K + K+
Sbjct:   53 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSDAEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKPLLKK 136

[Close]

BLAST of SOXB1-1 vs. Ensembl Medaka
Match: ENSORLT00000029054.1 (transcription factor Sox-14-like [Source:NCBI gene;Acc:111949029])

HSP 1 Score: 144.05 bits (362), Expect = 2.993e-39
Identity = 62/87 (71.26%), Postives = 76/87 (87.36%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K  + +KRPMNAFMVWSRGQRR+MA++NPKMHNSEISKRLG  WK LS+ DK+PFIDEAKRLRA H+ ++PDYKYRPRRK +A+ ++
Sbjct:    3 KPVEHIKRPMNAFMVWSRGQRRKMARENPKMHNSEISKRLGAEWKTLSDSDKRPFIDEAKRLRAQHLREHPDYKYRPRRKPRALLRR 89

[Close]

BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 939.102 bits (2426), Expect = 0.000e+0
Identity = 539/539 (100.00%), Postives = 539/539 (100.00%), Query Frame = 3

Query:   84 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 539

[Close]

BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 937.562 bits (2422), Expect = 0.000e+0
Identity = 538/538 (100.00%), Postives = 538/538 (100.00%), Query Frame = 3

Query:   87 MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 538

[Close]

BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000067682.1 (SMESG000067682.1)

HSP 1 Score: 153.68 bits (387), Expect = 7.839e-40
Identity = 91/181 (50.28%), Postives = 109/181 (60.22%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA-----------MDKQ-KKFLG--SAAMANVTALSHQLGREMGYFN-SGASGNGYL------ASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQ 1316
            KK+ R++RPMNAFMVWSRGQRR+M+ +NPKMHNSEISKRLG MWK+LSE DKKPFIDEAKRLRANH  ++PDYKYRPRRK K             DK  KK++   S    N    S  L  +  +      S N YL       +GY++    +D  P    MYY     +YP  QGP Q
Sbjct:  218 KKEARIRRPMNAFMVWSRGQRRKMSVENPKMHNSEISKRLGSMWKSLSEIDKKPFIDEAKRLRANHQKEHPDYKYRPRRKSKIAANSHPPTNMPQDKHGKKYVNPTSGHHNNQNIASTSLSSDFHFQQLQQDSANIYLGQQTGQGTGYSNYPVCLD--PNYGTMYYTPNGVIYP--QGPLQ 394

[Close]

BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000060099.1 (SMESG000060099.1)

HSP 1 Score: 153.68 bits (387), Expect = 7.839e-40
Identity = 91/181 (50.28%), Postives = 109/181 (60.22%), Query Frame = 3

Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA-----------MDKQ-KKFLG--SAAMANVTALSHQLGREMGYFN-SGASGNGYL------ASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQ 1316
            KK+ R++RPMNAFMVWSRGQRR+M+ +NPKMHNSEISKRLG MWK+LSE DKKPFIDEAKRLRANH  ++PDYKYRPRRK K             DK  KK++   S    N    S  L  +  +      S N YL       +GY++    +D  P    MYY     +YP  QGP Q
Sbjct:  218 KKEARIRRPMNAFMVWSRGQRRKMSVENPKMHNSEISKRLGSMWKSLSEIDKKPFIDEAKRLRANHQKEHPDYKYRPRRKSKIAANSHPPTNMPQDKHGKKYVNPTSGHHNNQNIASTSLSSDFHFQQLQQDSANIYLGQQTGQGTGYSNYPVCLD--PNYGTMYYTPNGVIYP--QGPLQ 394

[Close]

BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000077970.1 (SMESG000077970.1)

HSP 1 Score: 148.673 bits (374), Expect = 1.176e-39
Identity = 66/89 (74.16%), Postives = 78/89 (87.64%), Query Frame = 3

Query:  840 KDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K+D VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK+L+E  K+PFIDEAKRLRA HM  +PDYKYRPRRK K++ ++ K+
Sbjct:   65 KEDHVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKHLTELQKRPFIDEAKRLRAIHMKDHPDYKYRPRRKPKSIFRKDKY 153

The following BLAST results are available for this feature:

BLAST of SOXB1-1 vs. Ensembl Human
BLAST of SOXB1-1 vs. Ensembl Celegans
BLAST of SOXB1-1 vs. Ensembl Fly
BLAST of SOXB1-1 vs. Ensembl Zebrafish
BLAST of SOXB1-1 vs. Ensembl Xenopus
BLAST of SOXB1-1 vs. Ensembl Mouse
BLAST of SOXB1-1 vs. UniProt/SwissProt
BLAST of SOXB1-1 vs. TrEMBL
BLAST of SOXB1-1 vs. Ensembl Cavefish
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
BLAST of SOXB1-1 vs. Ensembl Yeast
BLAST of SOXB1-1 vs. Ensembl Nematostella
BLAST of SOXB1-1 vs. Ensembl Medaka
BLAST of SOXB1-1 vs. Planmine SMEST

BLAST of SOXB1-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SOX2	9.386e-41	78.16	SRY-box transcription factor 2 [Source:HGNC Symbol...	[more]
SOX14	1.382e-40	71.43	SRY-box transcription factor 14 [Source:HGNC Symbo...	[more]
SOX21	4.667e-40	66.97	SRY-box transcription factor 21 [Source:HGNC Symbo...	[more]
SOX1	3.805e-37	82.89	SRY-box transcription factor 1 [Source:HGNC Symbol...	[more]
SOX15	3.896e-36	73.75	SRY-box transcription factor 15 [Source:HGNC Symbo...	[more]

BLAST of SOXB1-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox-3	6.961e-42	70.83	SOX (Mammalian SRY box) family [Source:UniProtKB/...	[more]
sox-2	1.286e-41	77.01	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sox-2	1.286e-41	77.01	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sox-2	1.286e-41	77.01	Transcription factor sox-2 [Source:UniProtKB/Swis...	[more]
sox-4	1.573e-24	50.00	SOX (Mammalian SRY box) family [Source:UniProtKB/...	[more]

BLAST of SOXB1-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sox21a	2.588e-39	78.31	gene:FBgn0036411 transcript:FBtr0330178	[more]
Sox21a	2.730e-39	78.31	gene:FBgn0036411 transcript:FBtr0075748	[more]
SoxN	1.941e-38	84.21	gene:FBgn0029123 transcript:FBtr0079733	[more]
SoxN	3.986e-38	84.21	gene:FBgn0029123 transcript:FBtr0330210	[more]
Sox21b	2.204e-37	75.00	gene:FBgn0042630 transcript:FBtr0075747	[more]

BLAST of SOXB1-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox2	7.105e-41	77.01	SRY-box transcription factor 2 [Source:NCBI gene;A...	[more]
sox14	1.328e-40	71.43	SRY-box transcription factor 14 [Source:NCBI gene;...	[more]
sox21b	2.162e-40	74.44	SRY-box transcription factor 21b [Source:NCBI gene...	[more]
sox19b	3.118e-40	63.89	SRY-box transcription factor 19b [Source:NCBI gene...	[more]
sox21a	5.946e-39	73.33	SRY-box transcription factor 21a [Source:NCBI gene...	[more]

BLAST of SOXB1-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox2	1.932e-41	55.07	SRY-box 2 [Source:NCBI gene;Acc:407873]	[more]
spag16	2.982e-40	71.43	sperm associated antigen 16 [Source:Xenbase;Acc:XB...	[more]
gsr	3.585e-39	74.44	glutathione reductase [Source:Xenbase;Acc:XB-GENE-...	[more]
sox3	2.797e-38	82.89	SRY-box 3 [Source:NCBI gene;Acc:493228]	[more]
sox17b.3	1.209e-30	54.26	SRY-box 17 alpha [Source:NCBI gene;Acc:395066]	[more]

BLAST of SOXB1-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Sox2	5.638e-41	78.16	SRY (sex determining region Y)-box 2 [Source:MGI S...	[more]
Sox21	8.756e-41	67.89	SRY (sex determining region Y)-box 21 [Source:MGI ...	[more]
Sox14	9.204e-41	71.43	SRY (sex determining region Y)-box 14 [Source:MGI ...	[more]
Sox14	2.912e-38	57.72	SRY (sex determining region Y)-box 14 [Source:MGI ...	[more]
Sox1	2.462e-37	82.89	SRY (sex determining region Y)-box 1 [Source:MGI S...	[more]

BLAST of SOXB1-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O42569\|SOX2_XENLA	2.105e-41	55.80	Transcription factor Sox-2 OS=Xenopus laevis OX=83...	[more]
sp\|P48430\|SOX2_CHICK	3.668e-41	55.71	Transcription factor SOX-2 OS=Gallus gallus OX=903...	[more]
sp\|Q6NVN0\|SOX2_XENTR	1.024e-40	55.07	Transcription factor Sox-2 OS=Xenopus tropicalis O...	[more]
sp\|Q21305\|SOX2_CAEEL	1.636e-40	77.01	Transcription factor sox-2 OS=Caenorhabditis elega...	[more]
sp\|P48432\|SOX2_MOUSE	3.601e-40	78.16	Transcription factor SOX-2 OS=Mus musculus OX=1009...	[more]

BLAST of SOXB1-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0A7M699	0.000e+0	99.10	SOXB1-1 (Fragment) OS=Schmidtea polychroa OX=50054...	[more]
J7FQ58	0.000e+0	99.81	SoxB OS=Schmidtea mediterranea OX=79327 PE=2 SV=1	[more]
A0A2H1CRL6	1.207e-46	64.79	HMG box OS=Fasciola hepatica OX=6192 GN=D915_02355...	[more]
A0A183SQT9	6.211e-46	78.43	HMG box domain-containing protein OS=Schistocephal...	[more]
A0A504YLM5	7.827e-46	64.79	Transcription factor SOX-2 OS=Fasciola gigantica O...	[more]

BLAST of SOXB1-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox19b	7.682e-41	55.63	transcription factor Sox-19b [Source:NCBI gene;Acc...	[more]
sox2	1.082e-40	77.01	SRY-box transcription factor 2 [Source:NCBI gene;A...	[more]
ENSAMXT00000004288.2	1.697e-40	70.33	pep primary_assembly:Astyanax_mexicanus-2.0:13:150...	[more]
sox21b	2.344e-40	54.55	SRY-box transcription factor 21b [Source:NCBI gene...	[more]
ENSAMXT00000026650.2	1.314e-39	72.22	transcription factor Sox-14-like [Source:NCBI gene...	[more]

BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox1b	5.328e-40	81.82	SRY-box transcription factor 1b [Source:NCBI gene;...	[more]
sox4b	4.768e-29	60.23	SRY-box transcription factor 4b [Source:ZFIN;Acc:Z...	[more]
sox12	4.385e-27	61.04	SRY-box transcription factor 12 [Source:ZFIN;Acc:Z...	[more]
ENSPMAT00000010223.1	8.198e-27	53.75	pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 ge...	[more]
sox10	3.714e-25	54.67	SRY-box transcription factor 10 [Source:ZFIN;Acc:Z...	[more]

BLAST of SOXB1-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
ROX1	1.319e-9	37.50	Heme-dependent repressor of hypoxic genes; mediate...	[more]
ABF2	4.545e-6	35.71	Mitochondrial DNA-binding protein; involved in mit...	[more]

BLAST of SOXB1-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40934	1.801e-39	76.19	Predicted protein; Sox family protein B1 [Source:...	[more]
EDO32666	1.095e-37	68.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44142	4.618e-31	50.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47688	2.779e-28	56.82	Predicted protein; Sox family protein 2 [Source:U...	[more]
EDO39449	4.212e-28	61.54	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of SOXB1-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sox14	1.119e-40	71.43	SRY-box transcription factor 14 [Source:NCBI gene;...	[more]
sox2	1.125e-40	77.01	SRY-box transcription factor 2 [Source:NCBI gene;A...	[more]
sox21	2.001e-40	75.56	SRY-box transcription factor 21 [Source:NCBI gene;...	[more]
sox19b	1.771e-39	77.38	transcription factor Sox-19a [Source:NCBI gene;Acc...	[more]
ENSORLT00000029054.1	2.993e-39	71.26	transcription factor Sox-14-like [Source:NCBI gene...	[more]

BLAST of SOXB1-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000011244.1	0.000e+0	100.00	SMESG000011244.1	[more]
SMESG000011244.1	0.000e+0	100.00	SMESG000011244.1	[more]
SMESG000067682.1	7.839e-40	50.28	SMESG000067682.1	[more]
SMESG000060099.1	7.839e-40	50.28	SMESG000060099.1	[more]
SMESG000077970.1	1.176e-39	74.16	SMESG000077970.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025778 ID=SMED30025778|Name=SOXB1-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1738bp
GCCTGATTTAAGAAATTAATCAATTTCAATATAACCGATTTGTTTTTATT
GATCAATATTTATCATTATTAAATTCAATACTAATGATGTCAGCAACAGA
TTATACAAAAATCAATTCGAAATTTCATTTGAGCACAGATATAAGAGGAA
TCAGTACTCAATCTCCCAAGTCGCATTTATTTCCACAAGATTCAATTACT
CCTTATAGTTACAGCGGTCCAGAAAGCTATTACCTTTCATTTCTCGAGCA
TAATGATCCAGCAAACTACTCATCCGCCCTTTCATCCTACTATCAGAAAT
TAAGAAATACCTCTGTAAATTTTGATGTTCCAAACGATGTTTATGACAAC
ATTTATTCCAACTCTCTCCAATCGGAAAAGAATCCCTATGGCTCATACTT
TTCCAGTCCGACTCTCGATTCGAAATCTTTTGACGATTCGAAACTATCGA
GTCAAACAAATAATTTCGATTGTTTAAAACAGTTTTCTCAAATTGACACA
AACACCTTGCAAACAGTTCAAACGATTGCTGCTTTGCATTCTCGGCATCA
TTTGAGCTCAAGTTCTAGTATTGATGGTAATAACGTTGAACCCAATCACA
AATCCGATTCGTCACCCAATCCACCAACGACTCAGTGTCAAGGTGCTCAC
AGTTTTCCCACTTTAAACAATTCATCTTGTCAACAGAGGCCTGGATTACG
TACTCCGAAGTCCGAAGACATTGATCGGAATCAAAACGATTATTTTGACG
ACTGCGAATTTTCAAAGGATCAAACGCAAAACGTTACCACGGCAAACTCT
CAAACGTCTCAGTCCAATATCACGAGCAGTTCTCAAAAGAAAGATGATCG
AGTCAAACGTCCTATGAATGCTTTCATGGTTTGGTCGAGAGGTCAGCGTC
GAAGAATGGCTCAGGATAATCCGAAAATGCACAACAGTGAAATCAGTAAA
CGACTCGGTGGAATGTGGAAAAATCTCAGTGAAGAAGACAAAAAACCATT
TATAGATGAAGCCAAACGATTGCGCGCCAATCATATGACTCAGTATCCAG
ACTACAAATACCGACCCAGACGAAAACATAAGGCAATGGATAAACAGAAA
AAATTTCTTGGCAGTGCAGCAATGGCCAATGTAACTGCTCTCTCACACCA
GCTTGGCAGAGAGATGGGTTATTTCAATTCCGGAGCATCTGGAAACGGGT
ATCTGGCGTCCGGTTATGCTTCATTGGCTCATTCGATAGATTCAACTCCT
TATTCCAGTCACATGTATTACAACATGAGACATTCACTATATCCTAATAA
TCAAGGCCCATTTCAATCTCATCTATCTTCAACCCCAAATGCCGTCAGTA
ACTATATGAGCGGTCTTGTAAGTCCCCATTCCGCAAGTGACTATTCGTTA
CCCCCATACGGATCAAATTATATCTCAAATTCCTCTGCAGCATCAGCTAT
GACACAAAACGGTCTCAAAATGAACTGTTCATCAGATCCTATTGATTTTG
ATATGACCCAATCACTTTATATGCAAATGCCACCGTCTGCCGCTATGTAC
GATTTACCGGATATGAGTGGAATGCTGGCTGGCGTTCCGCAATCAATTTA
TCATCCTTCTTATCATCATCATTCTTCTTCATCATCATCGGCGGCGTCAG
GAAAACCTCATTCGTTAACTGCATCATATAATGAAGGGACACAGCCTTTA
TGATGTGACATATAATGTGTACATTGATTGAGTATCGA

protein sequence of SMED30025778-orf-1

>SMED30025778-orf-1 ID=SMED30025778-orf-1|Name=SMED30025778-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=540bp
MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYY
LSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKN
PYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAA
LHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQ
QRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSS
QKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSE
EDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV
TALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRH
SLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNS
SAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAG
VPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL*

Aliases

The feature 'SOXB1-1' has the following synonyms


Synonym
soxB

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000009	sigma neoblast
PLANA:0000017	photoreceptor neuron
PLANA:0000036	eye
PLANA:0000039	gamma neoblast
PLANA:0000103	central nervous system
PLANA:0000418	head
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036910	HMG_box_dom_sf
IPR009071	HMG_box_dom
IPR022097	SOX_fam

Vocabulary: **biological process**
Term	Definition
GO:0006355	regulation of transcription, DNA-templated

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR009071	High mobility group box domain	SMART	SM00398	hmgende2	coord: 256..326 e-value: 4.4E-29 score: 112.6
IPR009071	High mobility group box domain	PFAM	PF00505	HMG_box	coord: 257..325 e-value: 5.1E-27 score: 94.1
IPR009071	High mobility group box domain	PROSITE	PS50118	HMG_BOX_2	coord: 257..325 score: 22.635
IPR036910	High mobility group box domain superfamily	GENE3D	G3DSA:1.10.30.10		coord: 254..333 e-value: 4.1E-31 score: 109.3
IPR036910	High mobility group box domain superfamily	SUPERFAMILY	SSF47095	HMG-box	coord: 243..329
IPR022097	Transcription factor SOX	PFAM	PF12336	SOXp	coord: 326..400 e-value: 1.3E-4 score: 23.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 509..539
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 155..205
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 155..215
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 232..258
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 232..250
None	No IPR available	PANTHER	PTHR10270:SF161	SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATED	coord: 161..526
None	No IPR available	PANTHER	PTHR10270	SOX TRANSCRIPTION FACTOR	coord: 161..526
None	No IPR available	CDD	cd01388	SOX-TCF_HMG-box	coord: 256..327 e-value: 4.75958E-37 score: 129.34