SOXB1-1

Overview
NameSOXB1-1
Smed IDSMED30025778
Length (bp)1738
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of SOXB1-1 (SMED30025778) t-SNE clustered cells

Violin plots show distribution of expression levels for SOXB1-1 (SMED30025778) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of SOXB1-1 (SMED30025778) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for SOXB1-1 (SMED30025778) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30025778

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30025778SMESG000011244.1 SmedASXL_010283SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
X1 cellSMED30025778SMESG000011244.1 SmedASXL_010283SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30025778SMESG000011244.1 SmedASXL_010283SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015
FACS sorted cell population asexual adult RNA-sequencing evidence
head regionSMED30025778SMESG000011244.1 dd_Smed_v6_13215_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30025778SMESG000011244.1 Smed-soxBsmed_ncbi_20200123PMID:22884275
Lapan et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
eyeSMED30025778SMESG000011244.1 SMED30025778smed_20140614PMID:25254346
Scimone et al., 2014
whole organism asexual adult colorimetric in situ hybridization evidence
central nervous systemSMED30025778SMESG000011244.1 SMED30025778smed_20140614PMID:25254346
Scimone et al., 2014
whole organism asexual adult colorimetric in situ hybridization evidence
sigma neoblastSMED30025778SMESG000011244.1 SMED30025778smed_20140614PMID:25017721
van Wolfswinkel et al., 2014
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gamma neoblastSMED30025778SMESG000011244.1 SMED30025778smed_20140614PMID:25017721
van Wolfswinkel et al., 2014
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX2 (SRY-box transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:11195])

HSP 1 Score: 151.754 bits (382), Expect = 9.386e-41
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   39 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 125          
BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX14 (SRY-box transcription factor 14 [Source:HGNC Symbol;Acc:HGNC:11193])

HSP 1 Score: 149.058 bits (375), Expect = 1.382e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93          
BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX21 (SRY-box transcription factor 21 [Source:HGNC Symbol;Acc:HGNC:11197])

HSP 1 Score: 148.673 bits (374), Expect = 4.667e-40
Identity = 73/109 (66.97%), Postives = 82/109 (75.23%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF-------LGSAAMANVTAL 1142
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF       LG  A A   AL
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGGVADAEHPAL 111          
BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX1 (SRY-box transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:11189])

HSP 1 Score: 143.665 bits (361), Expect = 3.805e-37
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK +SE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 124          
BLAST of SOXB1-1 vs. Ensembl Human
Match: SOX15 (SRY-box transcription factor 15 [Source:HGNC Symbol;Acc:HGNC:11196])

HSP 1 Score: 134.806 bits (338), Expect = 3.896e-36
Identity = 59/80 (73.75%), Postives = 69/80 (86.25%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA 1085
            ++VKRPMNAFMVWS  QRR+MAQ NPKMHNSEISKRLG  WK L E++K+PF++EAKRLRA H+  YPDYKYRPRRK K+
Sbjct:   47 EKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRLRARHLRDYPDYKYRPRRKAKS 126          
BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-3 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q20201])

HSP 1 Score: 150.214 bits (378), Expect = 6.961e-42
Identity = 68/96 (70.83%), Postives = 81/96 (84.38%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV 1133
            D VKRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+ + +++   + AM  +
Sbjct:   46 DHVKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKQLSEQEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKSSNLKQQPRLNIAMPTI 141          
BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-2 (Transcription factor sox-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21305])

HSP 1 Score: 151.754 bits (382), Expect = 1.286e-41
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141          
BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-2 (Transcription factor sox-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21305])

HSP 1 Score: 151.754 bits (382), Expect = 1.286e-41
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141          
BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-2 (Transcription factor sox-2 [Source:UniProtKB/Swiss-Prot;Acc:Q21305])

HSP 1 Score: 151.754 bits (382), Expect = 1.286e-41
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141          
BLAST of SOXB1-1 vs. Ensembl Celegans
Match: sox-4 (SOX (Mammalian SRY box) family [Source:UniProtKB/TrEMBL;Acc:Q17922])

HSP 1 Score: 103.219 bits (256), Expect = 1.573e-24
Identity = 41/82 (50.00%), Postives = 59/82 (71.95%), Query Frame = 3
Query:  840 KDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA 1085
            ++ R+KRPMNAFMVWS+ +R+++A    K HNS+ISK LG  W+ + E +K PF++ AK+LR  H   +PDY YRPRR+ + 
Sbjct:  117 REPRIKRPMNAFMVWSQQRRQQIAATGQKFHNSDISKMLGAEWRKMEEHEKVPFVERAKQLREEHFNAHPDYVYRPRRRKRV 198          
BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21a (gene:FBgn0036411 transcript:FBtr0330178)

HSP 1 Score: 149.058 bits (375), Expect = 2.588e-39
Identity = 65/83 (78.31%), Postives = 73/83 (87.95%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            D +KRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK L+E  K+PFIDEAKRLRA HM ++PDYKYRPRRK K ++K
Sbjct:  119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNK 201          
BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21a (gene:FBgn0036411 transcript:FBtr0075748)

HSP 1 Score: 148.673 bits (374), Expect = 2.730e-39
Identity = 65/83 (78.31%), Postives = 73/83 (87.95%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            D +KRPMNAFMVWSRGQRR+MAQDNPKMHNSEISKRLG  WK L+E  K+PFIDEAKRLRA HM ++PDYKYRPRRK K ++K
Sbjct:  119 DHIKRPMNAFMVWSRGQRRKMAQDNPKMHNSEISKRLGAEWKLLTEGQKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLNK 201          
BLAST of SOXB1-1 vs. Ensembl Fly
Match: SoxN (gene:FBgn0029123 transcript:FBtr0079733)

HSP 1 Score: 149.828 bits (377), Expect = 1.941e-38
Identity = 64/76 (84.21%), Postives = 70/76 (92.11%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MA DNPKMHNSEISKRLG  WK+LSE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:  177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRR 252          
BLAST of SOXB1-1 vs. Ensembl Fly
Match: SoxN (gene:FBgn0029123 transcript:FBtr0330210)

HSP 1 Score: 150.599 bits (379), Expect = 3.986e-38
Identity = 64/76 (84.21%), Postives = 70/76 (92.11%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MA DNPKMHNSEISKRLG  WK+LSE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:  177 DRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDYKYRPRR 252          
BLAST of SOXB1-1 vs. Ensembl Fly
Match: Sox21b (gene:FBgn0042630 transcript:FBtr0075747)

HSP 1 Score: 146.747 bits (369), Expect = 2.204e-37
Identity = 63/84 (75.00%), Postives = 75/84 (89.29%), Query Frame = 3
Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDK 1094
            ++ +KRPMNAFMVWSR QRR++AQDNPKMHNSEISKRLG  WK L+EE+K+PFIDEAKRLRA HM ++PDYKYRPRRK KA+ +
Sbjct:  245 EEHIKRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRLGAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRR 328          
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 151.369 bits (381), Expect = 7.105e-41
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DR+KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   36 DRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 122          
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox14 (SRY-box transcription factor 14 [Source:NCBI gene;Acc:557661])

HSP 1 Score: 148.288 bits (373), Expect = 1.328e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPADHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93          
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox21b (SRY-box transcription factor 21b [Source:NCBI gene;Acc:406246])

HSP 1 Score: 147.902 bits (372), Expect = 2.162e-40
Identity = 67/90 (74.44%), Postives = 76/90 (84.44%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPMDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLMKKDKF 92          
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox19b (SRY-box transcription factor 19b [Source:NCBI gene;Acc:64812])

HSP 1 Score: 149.058 bits (375), Expect = 3.118e-40
Identity = 69/108 (63.89%), Postives = 85/108 (78.70%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMG 1169
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L++ +K+PFIDEAKRLRA HM +YPDYKY+PRRK KA+ K+   +G   +A    L+  + +  G
Sbjct:   51 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDVEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKALMKKDNPVGKYPLAAGNLLASAVAQGQG 158          
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Match: sox21a (SRY-box transcription factor 21a [Source:NCBI gene;Acc:30543])

HSP 1 Score: 144.05 bits (362), Expect = 5.946e-39
Identity = 66/90 (73.33%), Postives = 76/90 (84.44%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MA DNPKMHNSEISKRLGG WK LS+ +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ ++
Sbjct:    3 KPMDHVKRPMNAFMVWSRVQRRKMALDNPKMHNSEISKRLGGEWKLLSDSEKRPFIDEAKRLRAVHMKEHPDYKYRPRRKPKNLIKKDRY 92          
BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox2 (SRY-box 2 [Source:NCBI gene;Acc:407873])

HSP 1 Score: 153.295 bits (386), Expect = 1.932e-41
Identity = 76/138 (55.07%), Postives = 94/138 (68.12%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMGY-----FNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G         ++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGASLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172          
BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: spag16 (sperm associated antigen 16 [Source:Xenbase;Acc:XB-GENE-949128])

HSP 1 Score: 147.902 bits (372), Expect = 2.982e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPVDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93          
BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: gsr (glutathione reductase [Source:Xenbase;Acc:XB-GENE-997099])

HSP 1 Score: 145.976 bits (367), Expect = 3.585e-39
Identity = 67/90 (74.44%), Postives = 76/90 (84.44%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKF 92          
BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox3 (SRY-box 3 [Source:NCBI gene;Acc:493228])

HSP 1 Score: 144.436 bits (363), Expect = 2.797e-38
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LS+ +K+PFIDEAKRLRA HM +YPDYKYRPRR
Sbjct:   38 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSEKRPFIDEAKRLRAVHMKEYPDYKYRPRR 113          
BLAST of SOXB1-1 vs. Ensembl Xenopus
Match: sox17b.3 (SRY-box 17 alpha [Source:NCBI gene;Acc:395066])

HSP 1 Score: 124.79 bits (312), Expect = 1.209e-30
Identity = 51/94 (54.26%), Postives = 72/94 (76.60%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSA 1118
            K + R++RPMNAFMVW++ +R+R+AQ NP +HN+E+SK LG  WK+L+   K+PF+ EA+RLR  H+  YPDYKYRPRRK +   +++ FL SA
Sbjct:   56 KAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLASKRPFVKEAERLRVQHIQDYPDYKYRPRRKKQVKREEEGFLPSA 149          
BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox2 (SRY (sex determining region Y)-box 2 [Source:MGI Symbol;Acc:MGI:98364])

HSP 1 Score: 152.14 bits (383), Expect = 5.638e-41
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   41 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 127          
BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox21 (SRY (sex determining region Y)-box 21 [Source:MGI Symbol;Acc:MGI:2654070])

HSP 1 Score: 150.214 bits (378), Expect = 8.756e-41
Identity = 74/109 (67.89%), Postives = 83/109 (76.15%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF-------LGSAAMANVTAL 1142
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF       LGS A A   AL
Sbjct:    3 KPVDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFAFPVPYGLGSVADAEHPAL 111          
BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox14 (SRY (sex determining region Y)-box 14 [Source:MGI Symbol;Acc:MGI:98362])

HSP 1 Score: 149.058 bits (375), Expect = 9.204e-41
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPSDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93          
BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox14 (SRY (sex determining region Y)-box 14 [Source:MGI Symbol;Acc:MGI:98362])

HSP 1 Score: 139.813 bits (351), Expect = 2.912e-38
Identity = 71/123 (57.72%), Postives = 87/123 (70.73%), Query Frame = 3
Query:  861 PMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLA 1229
            PMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+     S+A+  +  + H L      +   AS  GY    + SL+
Sbjct:    2 PMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKD---SSSAIQKMGEVPHTLATSALPY---ASTLGYQNGAFGSLS 118          
BLAST of SOXB1-1 vs. Ensembl Mouse
Match: Sox1 (SRY (sex determining region Y)-box 1 [Source:MGI Symbol;Acc:MGI:98357])

HSP 1 Score: 143.665 bits (361), Expect = 2.462e-37
Identity = 63/76 (82.89%), Postives = 70/76 (92.11%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK +SE +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   49 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 124          
BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|O42569|SOX2_XENLA (Transcription factor Sox-2 OS=Xenopus laevis OX=8355 GN=sox2 PE=1 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 2.105e-41
Identity = 77/138 (55.80%), Postives = 95/138 (68.84%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMG-----YFNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G        A++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANAMTSGVGGSLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172          
BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|P48430|SOX2_CHICK (Transcription factor SOX-2 OS=Gallus gallus OX=9031 GN=SOX2 PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 3.668e-41
Identity = 78/140 (55.71%), Postives = 94/140 (67.14%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--------GSAAMANVTALSHQLGREMG-YFNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+         G+  M     +   LG  +    +S A  NG+   GY  +   +
Sbjct:   37 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGTNTMTTGVGVGATLGAGVNQRMDSYAHMNGWTNGGYGMMQEQL 176          
BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|Q6NVN0|SOX2_XENTR (Transcription factor Sox-2 OS=Xenopus tropicalis OX=8364 GN=sox2 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.024e-40
Identity = 76/138 (55.07%), Postives = 94/138 (68.12%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL--GSAAMANVTALSHQLGREMGY-----FNSGASGNGYLASGYASLAHSI 1238
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+   G         ++  +G  +G       ++ A  NG+   GY  +   +
Sbjct:   35 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGANPMTSGVGASLGAGVNQRMDTYAHMNGWTNGGYGMMQEQL 172          
BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|Q21305|SOX2_CAEEL (Transcription factor sox-2 OS=Caenorhabditis elegans OX=6239 GN=sox-2 PE=1 SV=2)

HSP 1 Score: 151.754 bits (382), Expect = 1.636e-40
Identity = 67/87 (77.01%), Postives = 79/87 (90.80%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K DDRVKRPMNAFMVWSRGQR++MA +NPKMHNSEISKRLG  WK LSE++K+PFIDEAKRLRA HM ++PDYKYRPRRK K+++K+
Sbjct:   55 KNDDRVKRPMNAFMVWSRGQRKKMALENPKMHNSEISKRLGTEWKMLSEQEKRPFIDEAKRLRAIHMKEHPDYKYRPRRKTKSINKK 141          
BLAST of SOXB1-1 vs. UniProt/SwissProt
Match: sp|P48432|SOX2_MOUSE (Transcription factor SOX-2 OS=Mus musculus OX=10090 GN=Sox2 PE=1 SV=2)

HSP 1 Score: 152.14 bits (383), Expect = 3.601e-40
Identity = 68/87 (78.16%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   41 DRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 127          
BLAST of SOXB1-1 vs. TrEMBL
Match: A0A0A7M699 (SOXB1-1 (Fragment) OS=Schmidtea polychroa OX=50054 GN=soxb1-1 PE=2 SV=1)

HSP 1 Score: 957.977 bits (2475), Expect = 0.000e+0
Identity = 548/553 (99.10%), Postives = 549/553 (99.28%), Query Frame = 3
Query:   42 VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVE NHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITS+SQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF GSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHS YPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEG QPL
Sbjct:    1 VFIDQYLSLLNSILMMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVETNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSNSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFXGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSXYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGAQPL 553          
BLAST of SOXB1-1 vs. TrEMBL
Match: J7FQ58 (SoxB OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 941.799 bits (2433), Expect = 0.000e+0
Identity = 538/539 (99.81%), Postives = 539/539 (100.00%), Query Frame = 3
Query:   84 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSS+SSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSTSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 539          
BLAST of SOXB1-1 vs. TrEMBL
Match: A0A2H1CRL6 (HMG box OS=Fasciola hepatica OX=6192 GN=D915_02355 PE=4 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 1.207e-46
Identity = 92/142 (64.79%), Postives = 105/142 (73.94%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLASGYASLAHSIDSTPYSS 1259
            KK+DRVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L E +KKPFIDEAKRLRANHM QYPDYKYRPRRKHK +D+QKK  G     N T + + +G  + G    G +G G LA G  ++    D+   SS
Sbjct:   30 KKEDRVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGSMWKGLGETEKKPFIDEAKRLRANHMAQYPDYKYRPRRKHKPLDRQKKTTG----LNATVMGNYMGSSLAGSGLVGRAGVG-LAPGSRTMTSLFDALGSSS 166          
BLAST of SOXB1-1 vs. TrEMBL
Match: A0A183SQT9 (HMG box domain-containing protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS6587 PE=4 SV=1)

HSP 1 Score: 175.252 bits (443), Expect = 6.211e-46
Identity = 80/102 (78.43%), Postives = 92/102 (90.20%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTAL 1142
            K+D+RVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L+E DKKPFIDEAKRLRANHM+QYPDYKYRPRR+H+ ++KQKK + + A A V+ L
Sbjct:    5 KRDERVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGTMWKALNESDKKPFIDEAKRLRANHMSQYPDYKYRPRRRHRPLEKQKKAVAAMAAATVSGL 106          
BLAST of SOXB1-1 vs. TrEMBL
Match: A0A504YLM5 (Transcription factor SOX-2 OS=Fasciola gigantica OX=46835 GN=FGIG_02653 PE=4 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 7.827e-46
Identity = 92/142 (64.79%), Postives = 105/142 (73.94%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLASGYASLAHSIDSTPYSS 1259
            KK+DRVKRPMNAFMVWSRGQRRRMAQ+NPKMHNSEISKRLG MWK L E +KKPFIDEAKRLRANHM QYPDYKYRPRRKHK +D+QKK  G     N T + + +G  + G    G +G G LA G  ++    D+   SS
Sbjct:  410 KKEDRVKRPMNAFMVWSRGQRRRMAQENPKMHNSEISKRLGSMWKGLGETEKKPFIDEAKRLRANHMAQYPDYKYRPRRKHKPLDRQKKTTG----LNATVMGNYMGSSLAGTGLVGRAGVG-LAPGSRTMTSLFDALGSSS 546          
BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox19b (transcription factor Sox-19b [Source:NCBI gene;Acc:103045346])

HSP 1 Score: 150.214 bits (378), Expect = 7.682e-41
Identity = 84/151 (55.63%), Postives = 97/151 (64.24%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREM-GYFNSGASGNGYLAS-----GYASLAHSID--STPYSSHMYYN 1274
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L++ +K+PFIDEAKRLRA HM +YPDYKY+PRRK K + K+    G   +   TA    L   M GY    A G GY A      GY    H  D     Y +H Y N
Sbjct:   52 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTDAEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKPLLKKDAPPGKYPL--TTAQGQALSPRMDGY--GWAPGGGYTAMQSDALGYTQQLHRYDLSGLQYPTHTYMN 198          
BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 149.058 bits (375), Expect = 1.082e-40
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   37 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 123          
BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: ENSAMXT00000004288.2 (pep primary_assembly:Astyanax_mexicanus-2.0:13:15067225:15068019:-1 gene:ENSAMXG00000004192.2 transcript:ENSAMXT00000004288.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.517 bits (371), Expect = 1.697e-40
Identity = 64/91 (70.33%), Postives = 79/91 (86.81%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+++++
Sbjct:    3 KPVDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKERYV 93          
BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: sox21b (SRY-box transcription factor 21b [Source:NCBI gene;Acc:406246])

HSP 1 Score: 147.132 bits (370), Expect = 2.344e-40
Identity = 78/143 (54.55%), Postives = 96/143 (67.13%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQK---KFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYS 1256
            K  + VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K++    F     +A   A + ++G  +G F S A    +L         SI + PYS
Sbjct:    3 KSGEHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRALHMKEHPDYKYRPRRKPKTLLKKEGKFAFPVPYGLAEHEA-ALKVGAGLGSFPSAALSEVFLNP-------SIPAHPYS 137          
BLAST of SOXB1-1 vs. Ensembl Cavefish
Match: ENSAMXT00000026650.2 (transcription factor Sox-14-like [Source:NCBI gene;Acc:103039590])

HSP 1 Score: 144.821 bits (364), Expect = 1.314e-39
Identity = 65/90 (72.22%), Postives = 74/90 (82.22%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSRGQRRRMA +NPKMHNSEISKRLG  WK LSE  K+P+IDEAKRLRA HM ++P+YKYRPRRK K + +  +F
Sbjct:    3 KSVDHVKRPMNAFMVWSRGQRRRMAMENPKMHNSEISKRLGAEWKLLSEAQKRPYIDEAKRLRAQHMKEHPNYKYRPRRKSKGLLRNDRF 92          
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox1b (SRY-box transcription factor 1b [Source:NCBI gene;Acc:562710])

HSP 1 Score: 149.443 bits (376), Expect = 5.328e-40
Identity = 63/77 (81.82%), Postives = 71/77 (92.21%), Query Frame = 3
Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            +DRVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK L+E +K+PFIDEAKRLRA HM ++PDYKYRPRR
Sbjct:   56 NDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLTEAEKRPFIDEAKRLRALHMKEHPDYKYRPRR 132          
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox4b (SRY-box transcription factor 4b [Source:ZFIN;Acc:ZDB-GENE-040426-1274])

HSP 1 Score: 117.857 bits (294), Expect = 4.768e-29
Identity = 53/88 (60.23%), Postives = 67/88 (76.14%), Query Frame = 3
Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGS 1115
            +KRPMNAFMVWS+ +RR++ + +P MHN+EISKRLG  WK L E +K PFI EA+RLR  HM  YPDYKYRPR+K K   +Q++  GS
Sbjct:   62 IKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGRRWKQLKESEKVPFIREAERLRLKHMADYPDYKYRPRKKAKLAQQQQQQQGS 149          
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox12 (SRY-box transcription factor 12 [Source:ZFIN;Acc:ZDB-GENE-040724-33])

HSP 1 Score: 112.079 bits (279), Expect = 4.385e-27
Identity = 47/77 (61.04%), Postives = 61/77 (79.22%), Query Frame = 3
Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHK 1082
            +KRPMNAFMVWS+ +RR++  ++P +HN+EISKRLG  WK L + +K PF+ EA+RLR  HM  YPDYKYRPR+K K
Sbjct:   60 IKRPMNAFMVWSQIERRKIMMESPDVHNAEISKRLGRRWKQLKDCEKVPFMREAERLRLKHMADYPDYKYRPRKKAK 136          
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010223.1 (pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 gene:ENSPMAG00000009255.1 transcript:ENSPMAT00000010223.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 103.219 bits (256), Expect = 8.198e-27
Identity = 43/80 (53.75%), Postives = 65/80 (81.25%), Query Frame = 3
Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHK 1082
            + R+ RPMNAFMVW++ +RRR+A+ NP +HN+E+SK LG  W+ L+ E ++P ++EA+RLR  H++++PDYKYRPRRK +
Sbjct:    3 EPRIPRPMNAFMVWAKDERRRLAKQNPDLHNAELSKMLGKSWRALTPESRRPCVEEAERLRLLHLSEHPDYKYRPRRKKQ 82          
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Match: sox10 (SRY-box transcription factor 10 [Source:ZFIN;Acc:ZDB-GENE-011207-1])

HSP 1 Score: 105.145 bits (261), Expect = 3.714e-25
Identity = 41/75 (54.67%), Postives = 61/75 (81.33%), Query Frame = 3
Query:  852 VKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRK 1076
            VKRPMNAFMVW++  RR+++   P++HN+E+SK LG +W+ L+E +K+PF++EA+RLR  H   +PDYKY+PRR+
Sbjct:  112 VKRPMNAFMVWAQAARRKLSDQYPQLHNAELSKTLGKLWRLLNEGEKRPFVEEAERLRMQHKKDHPDYKYQPRRR 186          
BLAST of SOXB1-1 vs. Ensembl Yeast
Match: ROX1 (Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269])

HSP 1 Score: 58.151 bits (139), Expect = 1.319e-9
Identity = 30/80 (37.50%), Postives = 46/80 (57.50%), Query Frame = 3
Query:  849 RVKRPMNAFMVWSRGQRRRM-----AQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRR 1073
            ++ RP NAF+++ +   R +     AQ     HNS ISK +G  WK L  EDK  + + A++ +  H  +YP+YKY+P R
Sbjct:    9 KIPRPKNAFILFRQHYHRILIDEWTAQGVEIPHNSNISKIIGTKWKGLQPEDKAHWENLAEKEKLEHERKYPEYKYKPVR 88          
BLAST of SOXB1-1 vs. Ensembl Yeast
Match: ABF2 (Mitochondrial DNA-binding protein; involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation; ABF2 has a paralog, IXR1, that arose from the whole genome duplication; human homolog TFAM can complement yeast abf2 mutant, rescuing the loss-of-mitochondrial DNA phenotype in a yeast abf2 strain [Source:SGD;Acc:S000004676])

HSP 1 Score: 45.4394 bits (106), Expect = 4.545e-6
Identity = 20/56 (35.71%), Postives = 35/56 (62.50%), Query Frame = 3
Query:  855 KRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRL 1022
            KRP +A+ ++ +  R +  ++NP +  +EISK  G  W+NL  + K+ +I E K+L
Sbjct:   44 KRPTSAYFLYLQDHRSQFVKENPTLRPAEISKIAGEKWQNLEADIKEKYISERKKL 99          
BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO40934 (Predicted protein; Sox family protein B1 [Source:UniProtKB/TrEMBL;Acc:Q3S381])

HSP 1 Score: 147.132 bits (370), Expect = 1.801e-39
Identity = 64/84 (76.19%), Postives = 75/84 (89.29%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            DRVKRPMNAFMVWSR +RR+MAQDNPKMHNSEISKRLG  WK LSE++K+P+IDEA+RLRA HM ++PDYKYRPRRK K + K+
Sbjct:   31 DRVKRPMNAFMVWSRERRRKMAQDNPKMHNSEISKRLGSEWKLLSEQEKRPYIDEARRLRAVHMKEHPDYKYRPRRKSKTLLKK 114          
BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO32666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUF3])

HSP 1 Score: 139.043 bits (349), Expect = 1.095e-37
Identity = 60/87 (68.97%), Postives = 76/87 (87.36%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K  + VKRPMNAFMVWSR +RR++AQ+NPKMHNSEISKRLG  WK L+++DKKPF++EAK+LRA HM ++PDYKYRPRRK K++ K+
Sbjct:    5 KPVEHVKRPMNAFMVWSREERRKIAQENPKMHNSEISKRLGSEWKQLADDDKKPFVEEAKKLRAQHMKEHPDYKYRPRRKPKSLLKK 91          
BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO44142 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWK8])

HSP 1 Score: 123.635 bits (309), Expect = 4.618e-31
Identity = 60/120 (50.00%), Postives = 83/120 (69.17%), Query Frame = 3
Query:  837 KKDD---RVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV--TALSHQLGRE-MGYFN 1178
            +KDD   R+KRPMNAFMVW++ +RRR+A  NP++HN+E+SK LG  W+ L+   K+PF+DEA+RLR  HM  YP+YKYRPRR+  +    K+  G+AA + V  TA     G+E +  FN
Sbjct:   65 EKDDETERIKRPMNAFMVWAQVERRRLADANPELHNAELSKMLGLTWRALNSTQKRPFVDEAERLRLQHMQDYPNYKYRPRRRKHSKRAAKRSTGAAAGSKVNGTACQKSSGQETVSRFN 184          
BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO47688 (Predicted protein; Sox family protein 2 [Source:UniProtKB/TrEMBL;Acc:Q3S383])

HSP 1 Score: 112.464 bits (280), Expect = 2.779e-28
Identity = 50/88 (56.82%), Postives = 68/88 (77.27%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQK 1100
            K  D +KRPMNA+MVWSR +RRR+A++ P+M NSEISKRLG  W +L+ ++K+P+++EAKRLR  H   +PDYKY+P+RK K   K K
Sbjct:    3 KPGDHIKRPMNAYMVWSRKERRRIAEECPRMLNSEISKRLGLEWNSLTLDEKQPYVEEAKRLRELHKKDHPDYKYQPKRKPKTSPKLK 90          
BLAST of SOXB1-1 vs. Ensembl Nematostella
Match: EDO39449 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9V3])

HSP 1 Score: 107.071 bits (266), Expect = 4.212e-28
Identity = 48/78 (61.54%), Postives = 58/78 (74.36%), Query Frame = 3
Query:  843 DDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRK 1076
            D  +KRPMNAFMVWSR +RR++A   P M N EISK LG  W  LSEE+K+PF+ EAKRLR  H  +YPDY Y+PRR+
Sbjct:    6 DQHIKRPMNAFMVWSRTERRKLALKYPNMLNCEISKLLGAEWSRLSEEEKRPFVTEAKRLRTIHNQKYPDYSYKPRRR 83          
BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox14 (SRY-box transcription factor 14 [Source:NCBI gene;Acc:100304454])

HSP 1 Score: 148.288 bits (373), Expect = 1.119e-40
Identity = 65/91 (71.43%), Postives = 78/91 (85.71%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFL 1109
            K  D +KRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+P+IDEAKRLRA HM ++PDYKYRPRRK K + K+ +++
Sbjct:    3 KPADHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPYIDEAKRLRAQHMKEHPDYKYRPRRKPKNLLKKDRYV 93          
BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox2 (SRY-box transcription factor 2 [Source:NCBI gene;Acc:378723])

HSP 1 Score: 148.673 bits (374), Expect = 1.125e-40
Identity = 67/87 (77.01%), Postives = 77/87 (88.51%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            +RVKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ K+
Sbjct:   38 ERVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKY 124          
BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox21 (SRY-box transcription factor 21 [Source:NCBI gene;Acc:100304456])

HSP 1 Score: 147.902 bits (372), Expect = 2.001e-40
Identity = 68/90 (75.56%), Postives = 76/90 (84.44%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K  D VKRPMNAFMVWSR QRR+MAQ+NPKMHNSEISKRLG  WK LSE +K+PFIDEAKRLRA HM ++PDYKYRPRRK K + K+ KF
Sbjct:    3 KPMDHVKRPMNAFMVWSRAQRRKMAQENPKMHNSEISKRLGAEWKLLSESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLMKKDKF 92          
BLAST of SOXB1-1 vs. Ensembl Medaka
Match: sox19b (transcription factor Sox-19a [Source:NCBI gene;Acc:110017107])

HSP 1 Score: 147.132 bits (370), Expect = 1.771e-39
Identity = 65/84 (77.38%), Postives = 75/84 (89.29%), Query Frame = 3
Query:  846 DRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            D+VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK LS+ +K+PFIDEAKRLRA HM +YPDYKY+PRRK K + K+
Sbjct:   53 DKVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSDAEKRPFIDEAKRLRAVHMKEYPDYKYKPRRKTKPLLKK 136          
BLAST of SOXB1-1 vs. Ensembl Medaka
Match: ENSORLT00000029054.1 (transcription factor Sox-14-like [Source:NCBI gene;Acc:111949029])

HSP 1 Score: 144.05 bits (362), Expect = 2.993e-39
Identity = 62/87 (71.26%), Postives = 76/87 (87.36%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQ 1097
            K  + +KRPMNAFMVWSRGQRR+MA++NPKMHNSEISKRLG  WK LS+ DK+PFIDEAKRLRA H+ ++PDYKYRPRRK +A+ ++
Sbjct:    3 KPVEHIKRPMNAFMVWSRGQRRKMARENPKMHNSEISKRLGAEWKTLSDSDKRPFIDEAKRLRAQHLREHPDYKYRPRRKPRALLRR 89          
BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 939.102 bits (2426), Expect = 0.000e+0
Identity = 539/539 (100.00%), Postives = 539/539 (100.00%), Query Frame = 3
Query:   84 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 539          
BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000011244.1 (SMESG000011244.1)

HSP 1 Score: 937.562 bits (2422), Expect = 0.000e+0
Identity = 538/538 (100.00%), Postives = 538/538 (100.00%), Query Frame = 3
Query:   87 MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTXXXXXXXXXXXXXQTNNFDCLKQFSQIDTNTLQTVQTIAAXXXXXXXXXXXXIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDXXXXXXXXXXXXXXXXXXXXXXKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNXXXXXXMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQXXXXXXXXXXXXXXXXXXXXXXXXLTASYNEGTQPL 1700
            MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL
Sbjct:    1 MSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYYLSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKNPYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAALHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQQRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSSQKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANVTALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNSSAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAGVPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL 538          
BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000067682.1 (SMESG000067682.1)

HSP 1 Score: 153.68 bits (387), Expect = 7.839e-40
Identity = 91/181 (50.28%), Postives = 109/181 (60.22%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA-----------MDKQ-KKFLG--SAAMANVTALSHQLGREMGYFN-SGASGNGYL------ASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQ 1316
            KK+ R++RPMNAFMVWSRGQRR+M+ +NPKMHNSEISKRLG MWK+LSE DKKPFIDEAKRLRANH  ++PDYKYRPRRK K             DK  KK++   S    N    S  L  +  +      S N YL       +GY++    +D  P    MYY     +YP  QGP Q
Sbjct:  218 KKEARIRRPMNAFMVWSRGQRRKMSVENPKMHNSEISKRLGSMWKSLSEIDKKPFIDEAKRLRANHQKEHPDYKYRPRRKSKIAANSHPPTNMPQDKHGKKYVNPTSGHHNNQNIASTSLSSDFHFQQLQQDSANIYLGQQTGQGTGYSNYPVCLD--PNYGTMYYTPNGVIYP--QGPLQ 394          
BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000060099.1 (SMESG000060099.1)

HSP 1 Score: 153.68 bits (387), Expect = 7.839e-40
Identity = 91/181 (50.28%), Postives = 109/181 (60.22%), Query Frame = 3
Query:  837 KKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKA-----------MDKQ-KKFLG--SAAMANVTALSHQLGREMGYFN-SGASGNGYL------ASGYASLAHSIDSTPYSSHMYYNMRHSLYPNNQGPFQ 1316
            KK+ R++RPMNAFMVWSRGQRR+M+ +NPKMHNSEISKRLG MWK+LSE DKKPFIDEAKRLRANH  ++PDYKYRPRRK K             DK  KK++   S    N    S  L  +  +      S N YL       +GY++    +D  P    MYY     +YP  QGP Q
Sbjct:  218 KKEARIRRPMNAFMVWSRGQRRKMSVENPKMHNSEISKRLGSMWKSLSEIDKKPFIDEAKRLRANHQKEHPDYKYRPRRKSKIAANSHPPTNMPQDKHGKKYVNPTSGHHNNQNIASTSLSSDFHFQQLQQDSANIYLGQQTGQGTGYSNYPVCLD--PNYGTMYYTPNGVIYP--QGPLQ 394          
BLAST of SOXB1-1 vs. Planmine SMEST
Match: SMESG000077970.1 (SMESG000077970.1)

HSP 1 Score: 148.673 bits (374), Expect = 1.176e-39
Identity = 66/89 (74.16%), Postives = 78/89 (87.64%), Query Frame = 3
Query:  840 KDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSEEDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKF 1106
            K+D VKRPMNAFMVWSRGQRR+MAQ+NPKMHNSEISKRLG  WK+L+E  K+PFIDEAKRLRA HM  +PDYKYRPRRK K++ ++ K+
Sbjct:   65 KEDHVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKHLTELQKRPFIDEAKRLRAIHMKDHPDYKYRPRRKPKSIFRKDKY 153          
The following BLAST results are available for this feature:
BLAST of SOXB1-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SOX29.386e-4178.16SRY-box transcription factor 2 [Source:HGNC Symbol... [more]
SOX141.382e-4071.43SRY-box transcription factor 14 [Source:HGNC Symbo... [more]
SOX214.667e-4066.97SRY-box transcription factor 21 [Source:HGNC Symbo... [more]
SOX13.805e-3782.89SRY-box transcription factor 1 [Source:HGNC Symbol... [more]
SOX153.896e-3673.75SRY-box transcription factor 15 [Source:HGNC Symbo... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox-36.961e-4270.83SOX (Mammalian SRY box) family [Source:UniProtKB/... [more]
sox-21.286e-4177.01Transcription factor sox-2 [Source:UniProtKB/Swis... [more]
sox-21.286e-4177.01Transcription factor sox-2 [Source:UniProtKB/Swis... [more]
sox-21.286e-4177.01Transcription factor sox-2 [Source:UniProtKB/Swis... [more]
sox-41.573e-2450.00SOX (Mammalian SRY box) family [Source:UniProtKB/... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sox21a2.588e-3978.31gene:FBgn0036411 transcript:FBtr0330178[more]
Sox21a2.730e-3978.31gene:FBgn0036411 transcript:FBtr0075748[more]
SoxN1.941e-3884.21gene:FBgn0029123 transcript:FBtr0079733[more]
SoxN3.986e-3884.21gene:FBgn0029123 transcript:FBtr0330210[more]
Sox21b2.204e-3775.00gene:FBgn0042630 transcript:FBtr0075747[more]
back to top
BLAST of SOXB1-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox27.105e-4177.01SRY-box transcription factor 2 [Source:NCBI gene;A... [more]
sox141.328e-4071.43SRY-box transcription factor 14 [Source:NCBI gene;... [more]
sox21b2.162e-4074.44SRY-box transcription factor 21b [Source:NCBI gene... [more]
sox19b3.118e-4063.89SRY-box transcription factor 19b [Source:NCBI gene... [more]
sox21a5.946e-3973.33SRY-box transcription factor 21a [Source:NCBI gene... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox21.932e-4155.07SRY-box 2 [Source:NCBI gene;Acc:407873][more]
spag162.982e-4071.43sperm associated antigen 16 [Source:Xenbase;Acc:XB... [more]
gsr3.585e-3974.44glutathione reductase [Source:Xenbase;Acc:XB-GENE-... [more]
sox32.797e-3882.89SRY-box 3 [Source:NCBI gene;Acc:493228][more]
sox17b.31.209e-3054.26SRY-box 17 alpha [Source:NCBI gene;Acc:395066][more]
back to top
BLAST of SOXB1-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Sox25.638e-4178.16SRY (sex determining region Y)-box 2 [Source:MGI S... [more]
Sox218.756e-4167.89SRY (sex determining region Y)-box 21 [Source:MGI ... [more]
Sox149.204e-4171.43SRY (sex determining region Y)-box 14 [Source:MGI ... [more]
Sox142.912e-3857.72SRY (sex determining region Y)-box 14 [Source:MGI ... [more]
Sox12.462e-3782.89SRY (sex determining region Y)-box 1 [Source:MGI S... [more]
back to top
BLAST of SOXB1-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|O42569|SOX2_XENLA2.105e-4155.80Transcription factor Sox-2 OS=Xenopus laevis OX=83... [more]
sp|P48430|SOX2_CHICK3.668e-4155.71Transcription factor SOX-2 OS=Gallus gallus OX=903... [more]
sp|Q6NVN0|SOX2_XENTR1.024e-4055.07Transcription factor Sox-2 OS=Xenopus tropicalis O... [more]
sp|Q21305|SOX2_CAEEL1.636e-4077.01Transcription factor sox-2 OS=Caenorhabditis elega... [more]
sp|P48432|SOX2_MOUSE3.601e-4078.16Transcription factor SOX-2 OS=Mus musculus OX=1009... [more]
back to top
BLAST of SOXB1-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0A7M6990.000e+099.10SOXB1-1 (Fragment) OS=Schmidtea polychroa OX=50054... [more]
J7FQ580.000e+099.81SoxB OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
A0A2H1CRL61.207e-4664.79HMG box OS=Fasciola hepatica OX=6192 GN=D915_02355... [more]
A0A183SQT96.211e-4678.43HMG box domain-containing protein OS=Schistocephal... [more]
A0A504YLM57.827e-4664.79Transcription factor SOX-2 OS=Fasciola gigantica O... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox19b7.682e-4155.63transcription factor Sox-19b [Source:NCBI gene;Acc... [more]
sox21.082e-4077.01SRY-box transcription factor 2 [Source:NCBI gene;A... [more]
ENSAMXT00000004288.21.697e-4070.33pep primary_assembly:Astyanax_mexicanus-2.0:13:150... [more]
sox21b2.344e-4054.55SRY-box transcription factor 21b [Source:NCBI gene... [more]
ENSAMXT00000026650.21.314e-3972.22transcription factor Sox-14-like [Source:NCBI gene... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox1b5.328e-4081.82SRY-box transcription factor 1b [Source:NCBI gene;... [more]
sox4b4.768e-2960.23SRY-box transcription factor 4b [Source:ZFIN;Acc:Z... [more]
sox124.385e-2761.04SRY-box transcription factor 12 [Source:ZFIN;Acc:Z... [more]
ENSPMAT00000010223.18.198e-2753.75pep scaffold:Pmarinus_7.0:GL478813:2555:9375:-1 ge... [more]
sox103.714e-2554.67SRY-box transcription factor 10 [Source:ZFIN;Acc:Z... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
ROX11.319e-937.50Heme-dependent repressor of hypoxic genes; mediate... [more]
ABF24.545e-635.71Mitochondrial DNA-binding protein; involved in mit... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO409341.801e-3976.19Predicted protein; Sox family protein B1 [Source:... [more]
EDO326661.095e-3768.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO441424.618e-3150.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO476882.779e-2856.82Predicted protein; Sox family protein 2 [Source:U... [more]
EDO394494.212e-2861.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of SOXB1-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
sox141.119e-4071.43SRY-box transcription factor 14 [Source:NCBI gene;... [more]
sox21.125e-4077.01SRY-box transcription factor 2 [Source:NCBI gene;A... [more]
sox212.001e-4075.56SRY-box transcription factor 21 [Source:NCBI gene;... [more]
sox19b1.771e-3977.38transcription factor Sox-19a [Source:NCBI gene;Acc... [more]
ENSORLT00000029054.12.993e-3971.26transcription factor Sox-14-like [Source:NCBI gene... [more]
back to top
BLAST of SOXB1-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000011244.10.000e+0100.00SMESG000011244.1[more]
SMESG000011244.10.000e+0100.00SMESG000011244.1[more]
SMESG000067682.17.839e-4050.28SMESG000067682.1[more]
SMESG000060099.17.839e-4050.28SMESG000060099.1[more]
SMESG000077970.11.176e-3974.16SMESG000077970.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025778 ID=SMED30025778|Name=SOXB1-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1738bp
GCCTGATTTAAGAAATTAATCAATTTCAATATAACCGATTTGTTTTTATT
GATCAATATTTATCATTATTAAATTCAATACTAATGATGTCAGCAACAGA
TTATACAAAAATCAATTCGAAATTTCATTTGAGCACAGATATAAGAGGAA
TCAGTACTCAATCTCCCAAGTCGCATTTATTTCCACAAGATTCAATTACT
CCTTATAGTTACAGCGGTCCAGAAAGCTATTACCTTTCATTTCTCGAGCA
TAATGATCCAGCAAACTACTCATCCGCCCTTTCATCCTACTATCAGAAAT
TAAGAAATACCTCTGTAAATTTTGATGTTCCAAACGATGTTTATGACAAC
ATTTATTCCAACTCTCTCCAATCGGAAAAGAATCCCTATGGCTCATACTT
TTCCAGTCCGACTCTCGATTCGAAATCTTTTGACGATTCGAAACTATCGA
GTCAAACAAATAATTTCGATTGTTTAAAACAGTTTTCTCAAATTGACACA
AACACCTTGCAAACAGTTCAAACGATTGCTGCTTTGCATTCTCGGCATCA
TTTGAGCTCAAGTTCTAGTATTGATGGTAATAACGTTGAACCCAATCACA
AATCCGATTCGTCACCCAATCCACCAACGACTCAGTGTCAAGGTGCTCAC
AGTTTTCCCACTTTAAACAATTCATCTTGTCAACAGAGGCCTGGATTACG
TACTCCGAAGTCCGAAGACATTGATCGGAATCAAAACGATTATTTTGACG
ACTGCGAATTTTCAAAGGATCAAACGCAAAACGTTACCACGGCAAACTCT
CAAACGTCTCAGTCCAATATCACGAGCAGTTCTCAAAAGAAAGATGATCG
AGTCAAACGTCCTATGAATGCTTTCATGGTTTGGTCGAGAGGTCAGCGTC
GAAGAATGGCTCAGGATAATCCGAAAATGCACAACAGTGAAATCAGTAAA
CGACTCGGTGGAATGTGGAAAAATCTCAGTGAAGAAGACAAAAAACCATT
TATAGATGAAGCCAAACGATTGCGCGCCAATCATATGACTCAGTATCCAG
ACTACAAATACCGACCCAGACGAAAACATAAGGCAATGGATAAACAGAAA
AAATTTCTTGGCAGTGCAGCAATGGCCAATGTAACTGCTCTCTCACACCA
GCTTGGCAGAGAGATGGGTTATTTCAATTCCGGAGCATCTGGAAACGGGT
ATCTGGCGTCCGGTTATGCTTCATTGGCTCATTCGATAGATTCAACTCCT
TATTCCAGTCACATGTATTACAACATGAGACATTCACTATATCCTAATAA
TCAAGGCCCATTTCAATCTCATCTATCTTCAACCCCAAATGCCGTCAGTA
ACTATATGAGCGGTCTTGTAAGTCCCCATTCCGCAAGTGACTATTCGTTA
CCCCCATACGGATCAAATTATATCTCAAATTCCTCTGCAGCATCAGCTAT
GACACAAAACGGTCTCAAAATGAACTGTTCATCAGATCCTATTGATTTTG
ATATGACCCAATCACTTTATATGCAAATGCCACCGTCTGCCGCTATGTAC
GATTTACCGGATATGAGTGGAATGCTGGCTGGCGTTCCGCAATCAATTTA
TCATCCTTCTTATCATCATCATTCTTCTTCATCATCATCGGCGGCGTCAG
GAAAACCTCATTCGTTAACTGCATCATATAATGAAGGGACACAGCCTTTA
TGATGTGACATATAATGTGTACATTGATTGAGTATCGA
back to top

protein sequence of SMED30025778-orf-1

>SMED30025778-orf-1 ID=SMED30025778-orf-1|Name=SMED30025778-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=540bp
MMSATDYTKINSKFHLSTDIRGISTQSPKSHLFPQDSITPYSYSGPESYY
LSFLEHNDPANYSSALSSYYQKLRNTSVNFDVPNDVYDNIYSNSLQSEKN
PYGSYFSSPTLDSKSFDDSKLSSQTNNFDCLKQFSQIDTNTLQTVQTIAA
LHSRHHLSSSSSIDGNNVEPNHKSDSSPNPPTTQCQGAHSFPTLNNSSCQ
QRPGLRTPKSEDIDRNQNDYFDDCEFSKDQTQNVTTANSQTSQSNITSSS
QKKDDRVKRPMNAFMVWSRGQRRRMAQDNPKMHNSEISKRLGGMWKNLSE
EDKKPFIDEAKRLRANHMTQYPDYKYRPRRKHKAMDKQKKFLGSAAMANV
TALSHQLGREMGYFNSGASGNGYLASGYASLAHSIDSTPYSSHMYYNMRH
SLYPNNQGPFQSHLSSTPNAVSNYMSGLVSPHSASDYSLPPYGSNYISNS
SAASAMTQNGLKMNCSSDPIDFDMTQSLYMQMPPSAAMYDLPDMSGMLAG
VPQSIYHPSYHHHSSSSSSAASGKPHSLTASYNEGTQPL*
back to top
Aliases
The feature 'SOXB1-1' has the following synonyms
Synonym
soxB
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000009sigma neoblast
PLANA:0000017photoreceptor neuron
PLANA:0000036eye
PLANA:0000039gamma neoblast
PLANA:0000103central nervous system
PLANA:0000418head
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR036910HMG_box_dom_sf
IPR009071HMG_box_dom
IPR022097SOX_fam
Vocabulary: biological process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009071High mobility group box domainSMARTSM00398hmgende2coord: 256..326
e-value: 4.4E-29
score: 112.6
IPR009071High mobility group box domainPFAMPF00505HMG_boxcoord: 257..325
e-value: 5.1E-27
score: 94.1
IPR009071High mobility group box domainPROSITEPS50118HMG_BOX_2coord: 257..325
score: 22.635
IPR036910High mobility group box domain superfamilyGENE3DG3DSA:1.10.30.10coord: 254..333
e-value: 4.1E-31
score: 109.3
IPR036910High mobility group box domain superfamilySUPERFAMILYSSF47095HMG-boxcoord: 243..329
IPR022097Transcription factor SOXPFAMPF12336SOXpcoord: 326..400
e-value: 1.3E-4
score: 23.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 509..539
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 155..205
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 155..215
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 232..258
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 232..250
NoneNo IPR availablePANTHERPTHR10270:SF161SOX DOMAIN-CONTAINING PROTEIN DICHAETE-RELATEDcoord: 161..526
NoneNo IPR availablePANTHERPTHR10270SOX TRANSCRIPTION FACTORcoord: 161..526
NoneNo IPR availableCDDcd01388SOX-TCF_HMG-boxcoord: 256..327
e-value: 4.75958E-37
score: 129.34