SH3 domain-containing kinase-binding protein 1
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025713 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 4
Homology
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Match: SH3D21 (SH3 domain containing 21 [Source:HGNC Symbol;Acc:HGNC:26236]) HSP 1 Score: 106.301 bits (264), Expect = 4.478e-24 Identity = 56/163 (34.36%), Postives = 84/163 (51.53%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQP 602
C + YS ADEL L+ G+I++ + E GW G NG+ G FP NFV+++ + + N + P+V KL + + D + SH P + +F Y+ E PDE+ + GD++KVL+K D GWW+G + G G+FP NFV P
Sbjct: 88 CKVNFSYSPEQADELKLQAGEIVEMIKEIEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPD---MPSVSPGPQRPPKLSSLAYDSPPDYLQTVSH-------PEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEG-ECQGRRGVFPDNFVLP 239
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Match: SH3KBP1 (SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867]) HSP 1 Score: 104.76 bits (260), Expect = 1.639e-23 Identity = 67/200 (33.50%), Postives = 107/200 (53.50%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENS 704
+++ I E+DY A H DEL++ G+II ++ + GW +G +NG+ G+FPDNFV+ IK + K K+ TN E L+ + S + T ++ + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS K SL E +
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMK----KDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRR-----CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLS-----KSSLRETT 179 HSP 2 Score: 63.1586 bits (152), Expect = 4.169e-10 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ DF+ N+
Sbjct: 272 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNR 336 HSP 3 Score: 63.1586 bits (152), Expect = 4.206e-10 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 275 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 324
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Match: SH3KBP1 (SH3 domain containing kinase binding protein 1 [Source:HGNC Symbol;Acc:HGNC:13867]) HSP 1 Score: 102.064 bits (253), Expect = 9.034e-23 Identity = 58/168 (34.52%), Postives = 97/168 (57.74%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFS 608
+++ I E+DY A H DEL++ G+II ++ + GW +G +NG+ G+FPDNFV+ IK + K K+ TN E L+ + S + T ++ + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMK----KDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRR-----RCQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELS 156 HSP 2 Score: 62.3882 bits (150), Expect = 8.187e-10 Identity = 27/54 (50.00%), Postives = 40/54 (74.07%), Query Frame = 3
Query: 438 VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+ IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 316 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 368 HSP 3 Score: 61.6178 bits (148), Expect = 1.218e-9 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ DF+ N+
Sbjct: 316 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNR 380
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Match: CD2AP (CD2 associated protein [Source:HGNC Symbol;Acc:HGNC:14258]) HSP 1 Score: 99.3673 bits (246), Expect = 8.265e-22 Identity = 62/176 (35.23%), Postives = 100/176 (56.82%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVI-FFETGWKKGWLNGKEGVFPDNFVKVIK--TDFKNTS----NKENGTNPNVEDNLNT----KTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++D I EYDY A H DEL+++ G+II++V E GW +G LNG+ G+FPDNFVK IK T+FK+ S + +G ++ ++T ++ H + K +K + +F Y +N DE+ ++VGDII + + +++GWW G ++G+FPSNFV+
Sbjct: 1 MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQ----------CKVLFEYIPQNEDELELKVGDIIDINEE--VEEGWWSGT-LNNKLGLFPSNFVK 163 HSP 2 Score: 71.2478 bits (173), Expect = 1.130e-12 Identity = 63/214 (29.44%), Postives = 92/214 (42.99%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK-TDFKNTSNKEN--------GTNP-----NVEDNLNTKT--------------------KLKTHSSDQKTKTTK-EKSHINNSLNEPL------------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
C ++Y + DEL LK GDII E GW G LN K G+FP NFVK ++ TD T ++ T+P NV + + KL+T +S +T+ K EK I SL +F+Y+ N DE+T + G+II +++K + GWW+G + G+ G+FP NF
Sbjct: 113 CKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRG-ELNGKEGVFPDNFA 325
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Match: SH3D21 (SH3 domain containing 21 [Source:HGNC Symbol;Acc:HGNC:26236]) HSP 1 Score: 84.3445 bits (207), Expect = 8.193e-17 Identity = 46/135 (34.07%), Postives = 68/135 (50.37%), Query Frame = 3
Query: 198 FETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQP 602
E GW G NG+ G FP NFV+++ + + N + P+V KL + + D + SH P + +F Y+ E PDE+ + GD++KVL+K D GWW+G + G G+FP NFV P
Sbjct: 5 IEDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDM---PSVSPGPQRPPKLSSLAYDSPPDYLQTVSH-------PEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEG-ECQGRRGVFPDNFVLP 128 HSP 2 Score: 53.5286 bits (127), Expect = 4.948e-7 Identity = 22/48 (45.83%), Postives = 31/48 (64.58%), Query Frame = 3
Query: 126 YDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFV 263
+DY DEL+L++GD++K S + GW +G G+ GVFPDNFV
Sbjct: 79 FDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFV 126
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Match: sem-5 (Sex muscle abnormal protein 5 [Source:UniProtKB/Swiss-Prot;Acc:P29355]) HSP 1 Score: 65.4698 bits (158), Expect = 5.598e-12 Identity = 57/219 (26.03%), Postives = 95/219 (43.38%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFE-TGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTN-----PNVEDNL-----------NTKTKLKTHSSDQKTKTTKE---KSHI----NNSLNEPL------------------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGS 620
M+ +AE+D+ A DELS K+G+ +K + E W K L+G EG P N++++ + ++ N P V D ++ S Q K ++ K ++ NSLNE + V+A+F + + E+ + GD+I ++NK+ D WW+G + GIFPSN+V P++ N S
Sbjct: 1 MEAVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNWYLGKITRNDAEVLLKKPTVRDGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKYYLWAVKFNSLNELVAYHRTASVSRTHTILLSDMNVETKFVQALFDFNPQESGELAFKRGDVITLINKD--DPNWWEG-QLNNRRGIFPSNYVCPYNSNKS 216
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 64.6994 bits (156), Expect = 6.103e-11 Identity = 50/174 (28.74%), Postives = 78/174 (44.83%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIF----FETGWKKGWLNGKEGVFPDNFVKVIKT------DFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVE---AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
C A + + A DELS + GD+I ++F E GW+ G L K G FP+ FV+ I D + N T + D + K K + T +++ ++ A F ++A N ++++ GD I+VL K + WKG GEIG FP ++V
Sbjct: 668 CRALFAFEARSEDELSFEPGDVI--IVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMK---WKGRNPAGEIGWFPKSYV 836 HSP 2 Score: 63.5438 bits (153), Expect = 1.747e-10 Identity = 46/162 (28.40%), Postives = 75/162 (46.30%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
CIA++ + A + ++LS KGD I+ + E WK G+ G FP ++VK + TS +P+ + T + S + + + I+ ++A ++ + VGD I VL KN D WWKG + G GIFP+N+V+
Sbjct: 787 CIAQFQWRARNEEDLSFAKGDTIEVLEKQEMKWKGRNPAGEIGWFPKSYVKEVGA---TTSTTTPIVSPSKASAGAPGAAAGAQYDVVPSDVTLQASE---TAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKN---DEWWKG-RCNGREGIFPANYVE 938
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 64.6994 bits (156), Expect = 6.318e-11 Identity = 50/175 (28.57%), Postives = 79/175 (45.14%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIF----FETGWKKGWLNGKEGVFPDNFVKVIKT------DFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVE---AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
C A + + A DELS + GD+I ++F E GW+ G L K G FP+ FV+ I D + N T + D + K K + T +++ ++ A F ++A N ++++ GD I+VL K + WKG GEIG FP ++V+
Sbjct: 666 CRALFAFEARSEDELSFEPGDVI--IVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMK---WKGRNPAGEIGWFPKSYVK 835 HSP 2 Score: 63.5438 bits (153), Expect = 1.825e-10 Identity = 46/162 (28.40%), Postives = 75/162 (46.30%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
CIA++ + A + ++LS KGD I+ + E WK G+ G FP ++VK + TS +P+ + T + S + + + I+ ++A ++ + VGD I VL KN D WWKG + G GIFP+N+V+
Sbjct: 785 CIAQFQWRARNEEDLSFAKGDTIEVLEKQEMKWKGRNPAGEIGWFPKSYVKEVGA---TTSTTTPIVSPSKASAGAPGAAAGAQYDVVPSDVTLQASE---TAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKN---DEWWKG-RCNGREGIFPANYVE 936
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 64.6994 bits (156), Expect = 7.260e-11 Identity = 52/182 (28.57%), Postives = 80/182 (43.96%), Query Frame = 3
Query: 90 FLIFFLMDCIAEYDYSATHADELSLKKGDIIKSVIF----FETGWKKGWLNGKEGVFPDNFVKVIKT------DFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVE---AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
F I C A + + A DELS + GD+I ++F E GW+ G L K G FP+ FV+ I D + N T + D + K K + T +++ ++ A F ++A N ++++ GD I+VL K + WKG GEIG FP ++V
Sbjct: 398 FNIHDTYKCRALFAFEARSEDELSFEPGDVI--IVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMK---WKGRNPAGEIGWFPKSYV 574 HSP 2 Score: 63.1586 bits (152), Expect = 1.993e-10 Identity = 47/166 (28.31%), Postives = 79/166 (47.59%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKS-HINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+ CIA++ + A + ++LS KGD I+ + E WK G+ G FP ++VK + TS T P V + + + Q + + + + + + I+ ++A ++ + VGD I VL KN D WWKG + G GIFP+N+V+
Sbjct: 522 ISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMKWKGRNPAGEIGWFPKSYVKEVGA---TTST----TTPIVSPSKASAGAPGAAAGAQYDVVPSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKN---DEWWKG-RCNGREGIFPANYVE 676
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Match: itsn-1 (ITSN (Intersectin) family [Source:UniProtKB/TrEMBL;Acc:E6N0W1]) HSP 1 Score: 64.6994 bits (156), Expect = 7.266e-11 Identity = 52/182 (28.57%), Postives = 80/182 (43.96%), Query Frame = 3
Query: 90 FLIFFLMDCIAEYDYSATHADELSLKKGDIIKSVIF----FETGWKKGWLNGKEGVFPDNFVKVIKT------DFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVE---AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
F I C A + + A DELS + GD+I ++F E GW+ G L K G FP+ FV+ I D + N T + D + K K + T +++ ++ A F ++A N ++++ GD I+VL K + WKG GEIG FP ++V
Sbjct: 400 FNIHDTYKCRALFAFEARSEDELSFEPGDVI--IVFQSHAAEPGWRAGQLREKVGWFPEAFVEAIAAVPTPGGDPPIQNMPPNMTPSSSVDQIGVKAARKAEIAAAMGLTEGGAPPASSAPAAAAVISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMK---WKGRNPAGEIGWFPKSYV 576 HSP 2 Score: 63.1586 bits (152), Expect = 2.048e-10 Identity = 47/166 (28.31%), Postives = 79/166 (47.59%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKS-HINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+ CIA++ + A + ++LS KGD I+ + E WK G+ G FP ++VK + TS T P V + + + Q + + + + + + I+ ++A ++ + VGD I VL KN D WWKG + G GIFP+N+V+
Sbjct: 524 ISQCIAQFQWRARNEEDLSFAKGDTIEVLEKQEMKWKGRNPAGEIGWFPKSYVKEVGA---TTST----TTPIVSPSKASAGAPGAAAGAQYDVVPSDVTLQASETAPQQQLYTVIYDFEAVETTDLALHVGDTILVLEKN---DEWWKG-RCNGREGIFPANYVE 678
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Match: cindr (gene:FBgn0027598 transcript:FBtr0085704) HSP 1 Score: 109.383 bits (272), Expect = 2.289e-25 Identity = 57/164 (34.76%), Postives = 93/164 (56.71%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWL--NGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
I EY+Y+A DEL L+KG II + GW +G L +G G+FPDNFV+V+++ + N G+ ++E + + K+ +S+++ K I+SY N DE+T+ VGD+I+ L + +++GWW+G R+ ++G+FPSNFVQ
Sbjct: 7 AIVEYEYAAKEPDELDLQKGAIIHRIKQMPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSNGNGTTGSGDHIEVGTAVQLRDKSATSNRRCKV-------------------IYSYTQVNDDELTLAVGDVIEFLGE--VEEGWWRGRLRS-KVGVFPSNFVQ 148 HSP 2 Score: 58.5362 bits (140), Expect = 7.535e-9 Identity = 25/50 (50.00%), Postives = 35/50 (70.00%), Query Frame = 3
Query: 450 FSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
F Y +N DE+ ++V DII V++ L D GWWKG R G++G+FP NFV+
Sbjct: 262 FPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIR-GKVGVFPDNFVK 310 HSP 3 Score: 54.6842 bits (130), Expect = 1.135e-7 Identity = 29/56 (51.79%), Postives = 36/56 (64.29%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFET---GWKKGWLNGKEGVFPDNFVKVI 272
C E+ Y+ + DEL LK DII +VI E GW KG + GK GVFPDNFVK++
Sbjct: 258 CRVEFPYAPQNDDELELKVDDII-AVISTELPDKGWWKGEIRGKVGVFPDNFVKML 312 HSP 4 Score: 52.373 bits (124), Expect = 5.931e-7 Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK 275
C Y Y+ + DEL+L GD+I+ + E GW +G L K GVFP NFV+ I+
Sbjct: 98 CKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIE 151
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Match: cindr (gene:FBgn0027598 transcript:FBtr0310424) HSP 1 Score: 109.383 bits (272), Expect = 2.411e-25 Identity = 57/164 (34.76%), Postives = 93/164 (56.71%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWL--NGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
I EY+Y+A DEL L+KG II + GW +G L +G G+FPDNFV+V+++ + N G+ ++E + + K+ +S+++ K I+SY N DE+T+ VGD+I+ L + +++GWW+G R+ ++G+FPSNFVQ
Sbjct: 7 AIVEYEYAAKEPDELDLQKGAIIHRIKQMPGGWWQGTLKASGVTGMFPDNFVRVLESGVSSNGNGTTGSGDHIEVGTAVQLRDKSATSNRRCKV-------------------IYSYTQVNDDELTLAVGDVIEFLGE--VEEGWWRGRLRS-KVGVFPSNFVQ 148 HSP 2 Score: 58.5362 bits (140), Expect = 7.957e-9 Identity = 25/50 (50.00%), Postives = 35/50 (70.00%), Query Frame = 3
Query: 450 FSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
F Y +N DE+ ++V DII V++ L D GWWKG R G++G+FP NFV+
Sbjct: 262 FPYAPQNDDELELKVDDIIAVISTELPDKGWWKGEIR-GKVGVFPDNFVK 310 HSP 3 Score: 54.6842 bits (130), Expect = 1.283e-7 Identity = 29/56 (51.79%), Postives = 36/56 (64.29%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFET---GWKKGWLNGKEGVFPDNFVKVI 272
C E+ Y+ + DEL LK DII +VI E GW KG + GK GVFPDNFVK++
Sbjct: 258 CRVEFPYAPQNDDELELKVDDII-AVISTELPDKGWWKGEIRGKVGVFPDNFVKML 312 HSP 4 Score: 52.373 bits (124), Expect = 6.410e-7 Identity = 24/54 (44.44%), Postives = 33/54 (61.11%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK 275
C Y Y+ + DEL+L GD+I+ + E GW +G L K GVFP NFV+ I+
Sbjct: 98 CKVIYSYTQVNDDELTLAVGDVIEFLGEVEEGWWRGRLRSKVGVFPSNFVQHIE 151
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Match: CAP (gene:FBgn0033504 transcript:FBtr0088346) HSP 1 Score: 83.5741 bits (205), Expect = 1.233e-17 Identity = 54/183 (29.51%), Postives = 93/183 (50.82%), Query Frame = 3
Query: 120 AEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVI----------KTDFKNTSNKENGTNPNVE---DNLNTKTKLKTHSSDQ---------KTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
A+Y++ A ELSL KG+++ + W +G + ++G+FP ++V+V+ +T TS PN++ N+N + T + Q +T + H++ S +EPL A++ Y+ +N DE+ + GD++ VL K DDGW+ G +RTG G FP N+V+
Sbjct: 132 AKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTS-SEPLAYRALYKYRPQNSDELELLEGDVVHVLEK--CDDGWFVGTSQRTGCFGTFPGNYVE 311
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Match: CAP (gene:FBgn0033504 transcript:FBtr0299828) HSP 1 Score: 83.5741 bits (205), Expect = 1.233e-17 Identity = 54/183 (29.51%), Postives = 93/183 (50.82%), Query Frame = 3
Query: 120 AEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVI----------KTDFKNTSNKENGTNPNVE---DNLNTKTKLKTHSSDQ---------KTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
A+Y++ A ELSL KG+++ + W +G + ++G+FP ++V+V+ +T TS PN++ N+N + T + Q +T + H++ S +EPL A++ Y+ +N DE+ + GD++ VL K DDGW+ G +RTG G FP N+V+
Sbjct: 132 AKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTS-SEPLAYRALYKYRPQNSDELELLEGDVVHVLEK--CDDGWFVGTSQRTGCFGTFPGNYVE 311
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Match: CAP (gene:FBgn0033504 transcript:FBtr0088338) HSP 1 Score: 84.3445 bits (207), Expect = 3.255e-17 Identity = 54/183 (29.51%), Postives = 93/183 (50.82%), Query Frame = 3
Query: 120 AEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVI----------KTDFKNTSNKENGTNPNVE---DNLNTKTKLKTHSSDQ---------KTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
A+Y++ A ELSL KG+++ + W +G + ++G+FP ++V+V+ +T TS PN++ N+N + T + Q +T + H++ S +EPL A++ Y+ +N DE+ + GD++ VL K DDGW+ G +RTG G FP N+V+
Sbjct: 458 AKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTS-SEPLAYRALYKYRPQNSDELELLEGDVVHVLEK--CDDGWFVGTSQRTGCFGTFPGNYVE 637
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Match: sh3kbp1 (SH3-domain kinase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-091204-186]) HSP 1 Score: 102.834 bits (255), Expect = 4.270e-23 Identity = 57/165 (34.55%), Postives = 99/165 (60.00%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+++ I E+DY + H DEL++ GDII ++ E GW +G L+G+ G+FPDNFV+ IK + K KE+ +K+ L S+ +++ + + + + +A FSY +N DE+ +++GD+I VL + +++GWW+G+ R G+ G+FPSNF +
Sbjct: 1 MVEAIVEFDYQSQHDDELTIAVGDIISNIRKDEGGWWEGELDGRRGLFPDNFVREIKKESKKEVKKESSL-------AGSKSDLSNGSASPRSEPSLRPAKKGEMIRK-RRCKAAFSYTPQNEDELELKIGDVIDVLGE--VEEGWWEGVLR-GKTGMFPSNFTK 154 HSP 2 Score: 61.2326 bits (147), Expect = 1.284e-9 Identity = 26/53 (49.06%), Postives = 39/53 (73.58%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPF 605
IF Y+A+N DE++I+ GDI+ ++NK+ D GWW G + G+ G+FP NFV+ F
Sbjct: 307 IFPYEAQNEDELSIKEGDIVTIINKDCADAGWWLG-ELNGKKGVFPDNFVKLF 358 HSP 3 Score: 56.225 bits (134), Expect = 4.512e-8 Identity = 28/56 (50.00%), Postives = 38/56 (67.86%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVI---FFETGWKKGWLNGKEGVFPDNFVKVI 272
C + Y A + DELS+K+GDI+ ++I + GW G LNGK+GVFPDNFVK+
Sbjct: 304 CKVIFPYEAQNEDELSIKEGDIV-TIINKDCADAGWWLGELNGKKGVFPDNFVKLF 358 HSP 4 Score: 54.299 bits (129), Expect = 1.675e-7 Identity = 24/65 (36.92%), Postives = 39/65 (60.00%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKEN 308
C A + Y+ + DEL LK GD+I + E GW +G L GK G+FP NF K + + ++ + +++
Sbjct: 104 CKAAFSYTPQNEDELELKIGDVIDVLGEVEEGWWEGVLRGKTGMFPSNFTKEVLAEVEDLTPQDD 168
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Match: sh3kbp1 (SH3-domain kinase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-091204-186]) HSP 1 Score: 101.679 bits (252), Expect = 9.818e-23 Identity = 57/164 (34.76%), Postives = 98/164 (59.76%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++ I E+DY + H DEL++ GDII ++ E GW +G L+G+ G+FPDNFV+ IK + K KE+ +K+ L S+ +++ + + + + +A FSY +N DE+ +++GD+I VL + +++GWW+G+ R G+ G+FPSNF +
Sbjct: 1 VEAIVEFDYQSQHDDELTIAVGDIISNIRKDEGGWWEGELDGRRGLFPDNFVREIKKESKKEVKKESSL-------AGSKSDLSNGSASPRSEPSLRPAKKGEMIRK-RRCKAAFSYTPQNEDELELKIGDVIDVLGE--VEEGWWEGVLR-GKTGMFPSNFTK 153 HSP 2 Score: 61.2326 bits (147), Expect = 1.250e-9 Identity = 26/53 (49.06%), Postives = 39/53 (73.58%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPF 605
IF Y+A+N DE++I+ GDI+ ++NK+ D GWW G + G+ G+FP NFV+ F
Sbjct: 306 IFPYEAQNEDELSIKEGDIVTIINKDCADAGWWLG-ELNGKKGVFPDNFVKLF 357 HSP 3 Score: 56.225 bits (134), Expect = 4.392e-8 Identity = 28/56 (50.00%), Postives = 38/56 (67.86%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVI---FFETGWKKGWLNGKEGVFPDNFVKVI 272
C + Y A + DELS+K+GDI+ ++I + GW G LNGK+GVFPDNFVK+
Sbjct: 303 CKVIFPYEAQNEDELSIKEGDIV-TIINKDCADAGWWLGELNGKKGVFPDNFVKLF 357 HSP 4 Score: 54.6842 bits (130), Expect = 1.616e-7 Identity = 24/65 (36.92%), Postives = 39/65 (60.00%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKEN 308
C A + Y+ + DEL LK GD+I + E GW +G L GK G+FP NF K + + ++ + +++
Sbjct: 103 CKAAFSYTPQNEDELELKIGDVIDVLGEVEEGWWEGVLRGKTGMFPSNFTKEVLAEVEDLTPQDD 167
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Match: sh3d21 (SH3 domain containing 21 [Source:ZFIN;Acc:ZDB-GENE-051120-57]) HSP 1 Score: 86.2705 bits (212), Expect = 6.255e-18 Identity = 57/165 (34.55%), Postives = 83/165 (50.30%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFF-ETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
M+ + + AT DEL++ GDI+K+V E GW +G L GK G+FP NFVK + SN+E S +KTK T ++ E +F Y + DE+ + VG+ I++L + I+DGWW G K+ +IG FPSNFV+
Sbjct: 1 MEVLVLLGFEATMPDELTVHVGDIVKNVSKAKEEGWLEGDLRGKRGMFPGNFVKEVPVYLIGDSNRE-------------------PRSIRKTKKTTVQTR---------KCEVVFPYVPTHEDELQLLVGETIEILRE--IEDGWWMG-KKNNQIGAFPSNFVK 134 HSP 2 Score: 84.3445 bits (207), Expect = 2.910e-17 Identity = 54/161 (33.54%), Postives = 75/161 (46.58%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
C + Y TH DEL L G+ I+ + E GW G N + G FP NFVK I K D+ + KL ++ K + S + N + +F Y A DE+ ++ GD+I V+NK+ DDGWW+G + G G FP NFV
Sbjct: 84 CEVVFPYVPTHEDELQLLVGETIEILREIEDGWWMGKKNNQIGAFPSNFVKEIFVPSK--------------DDAKARPKLSGSVFGKEGKLQQRPSLRKKTSNVKECCQVMFDYAAVAEDELNLKKGDVITVINKSTEDDGWWEG-EVNGRRGFFPDNFV 229 HSP 3 Score: 62.7734 bits (151), Expect = 2.900e-10 Identity = 41/99 (41.41%), Postives = 56/99 (56.57%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFET---GWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNP----NVEDNLNTKTKLKTHSSDQKTKT 389
C +DY+A DEL+LKKGD+I +VI T GW +G +NG+ G FPDNFV +I + T N G P + +D+ N + +SSD K KT
Sbjct: 178 CQVMFDYAAVAEDELNLKKGDVI-TVINKSTEDDGWWEGEVNGRRGFFPDNFVMLIPAETLQTGNA--GQAPVRSGSKKDSENQMPVMDQNSSDTKPKT 273
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Match: BX537102.1 (pep chromosome:GRCz11:CHR_ALT_CTG14_1_23:29792466:29823458:-1 gene:ENSDARG00000113693.1 transcript:ENSDART00000192695.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX537102.1) HSP 1 Score: 79.7221 bits (195), Expect = 8.716e-16 Identity = 52/171 (30.41%), Postives = 91/171 (53.22%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNG--KEGVFPDNFVKVIK-TDFKNTSNKENGTNPNV--EDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
+ + +A Y+++A ELSL+KG+ + V + W +G + G K+G+FP ++V VIK T +NT + P D LN++++ + ++ D EP +A+++Y N DE+ ++ GD++ V+ K DDGW+ G +RT G FP N+V+
Sbjct: 293 IGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPL-----------QGGGEPF--QALYNYMPRNEDELELKEGDVVDVMEK--CDDGWFVGTSRRTKFFGTFPGNYVK 448
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Match: BX537102.1 (pep chromosome:GRCz11:CHR_ALT_CTG14_1_23:29792466:29823458:-1 gene:ENSDARG00000113693.1 transcript:ENSDART00000188060.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX537102.1) HSP 1 Score: 79.7221 bits (195), Expect = 9.359e-16 Identity = 52/171 (30.41%), Postives = 91/171 (53.22%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNG--KEGVFPDNFVKVIK-TDFKNTSNKENGTNPNV--EDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
+ + +A Y+++A ELSL+KG+ + V + W +G + G K+G+FP ++V VIK T +NT + P D LN++++ + ++ D EP +A+++Y N DE+ ++ GD++ V+ K DDGW+ G +RT G FP N+V+
Sbjct: 279 IGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPL-----------QGGGEPF--QALYNYMPRNEDELELKEGDVVDVMEK--CDDGWFVGTSRRTKFFGTFPGNYVK 434
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Match: tmprss9 (transmembrane serine protease 9 [Source:Xenbase;Acc:XB-GENE-993973]) HSP 1 Score: 102.834 bits (255), Expect = 6.009e-23 Identity = 56/163 (34.36%), Postives = 90/163 (55.21%), Query Frame = 3
Query: 111 DCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
D I E+DY A H DEL++ GDII + + GW +G L G+ G+FPDNFV+ +K D K N + P T+ ++ + + +S + FSY +N DE+ ++VG+II+VL + +++GWW+G+ G+ G+FPSNF++
Sbjct: 39 DAIVEFDYKAQHEDELTITAGDIITKIKKEDGGWWEGELKGRRGLFPDNFVRELKKDTKKEQNSKPPDRP---------TQGISNGNALLSSEAVIRSAGRGERTRRRRCQVAFSYLPQNEDELELKVGEIIEVLGE--VEEGWWEGV-LNGKTGMFPSNFIR 189 HSP 2 Score: 94.7449 bits (234), Expect = 3.094e-20 Identity = 68/216 (31.48%), Postives = 100/216 (46.30%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVK-------------VIKTDFKNTSNKEN--------GTNPNVEDNLNTKT---------------KLKTHSSDQKT------KTTKEKSHINNSLNEPLIVE------------AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
C + Y + DEL LK G+II+ + E GW +G LNGK G+FP NF++ IKT FK+T+ E+ GTN +K KL+ S + ++ K +K + EP+ +E +F Y+A N DE+TI GDI+ VL+K +D GWW+G + G+ G+FP NFV+
Sbjct: 139 CQVAFSYLPQNEDELELKVGEIIEVLGEVEEGWWEGVLNGKTGMFPSNFIREIVTETEIGNFEQQIKTAFKDTTGSESDGGDSKLEGTNGTSGGETQSKRIRGFGFGDIFKDKPIKLRPRSIEMESEIVPIEKAMGKKMPPTVTSQEPMKIETESKTKRKEYCKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEG-ELNGKKGVFPDNFVK 353 HSP 3 Score: 61.6178 bits (148), Expect = 1.321e-9 Identity = 28/60 (46.67%), Postives = 41/60 (68.33%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFK 287
C + Y A + DEL+++ GDI+ S + GW +G LNGK+GVFPDNFVK++ +DF+
Sbjct: 301 CKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEGELNGKKGVFPDNFVKLLPSDFE 360
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Match: tmprss9 (transmembrane serine protease 9 [Source:Xenbase;Acc:XB-GENE-993973]) HSP 1 Score: 97.0561 bits (240), Expect = 4.042e-21 Identity = 53/158 (33.54%), Postives = 87/158 (55.06%), Query Frame = 3
Query: 126 YDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+DY A H DEL++ GDII + + GW +G L G+ G+FPDNFV+ +K D K N + P T+ ++ + + +S + FSY +N DE+ ++VG+II+VL + +++GWW+G+ G+ G+FPSNF++
Sbjct: 10 FDYKAQHEDELTITAGDIITKIKKEDGGWWEGELKGRRGLFPDNFVRELKKDTKKEQNSKPPDRP---------TQGISNGNALLSSEAVIRSAGRGERTRRRRCQVAFSYLPQNEDELELKVGEIIEVLGE--VEEGWWEGV-LNGKTGMFPSNFIR 155 HSP 2 Score: 86.2705 bits (212), Expect = 1.626e-17 Identity = 64/223 (28.70%), Postives = 99/223 (44.39%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVK--VIKTDFKN-------------------TSNKENGTNPNVEDNLNT----------------------KTKLKTHSSDQKT------KTTKEKSHINNSLNEPLIVE------------AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
C + Y + DEL LK G+II+ + E GW +G LNGK G+FP NF++ V +T+ N T ++ +G + +E T KL+ S + ++ K +K + EP+ +E +F Y+A N DE+TI GDI+ VL+K +D GWW+G + G+ G+FP NFV+
Sbjct: 105 CQVAFSYLPQNEDELELKVGEIIEVLGEVEEGWWEGVLNGKTGMFPSNFIREIVTETEIGNFDLSSFLELSLIFHLQNDTTGSESDGGDSKLEGTNGTSGGETQSKRIRGFGFGDIFKDKPIKLRPRSIEMESEIVPIEKAMGKKMPPTVTSQEPMKIETESKTKRKEYCKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEG-ELNGKKGVFPDNFVK 326 HSP 3 Score: 62.003 bits (149), Expect = 9.148e-10 Identity = 28/60 (46.67%), Postives = 41/60 (68.33%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFK 287
C + Y A + DEL+++ GDI+ S + GW +G LNGK+GVFPDNFVK++ +DF+
Sbjct: 274 CKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEGELNGKKGVFPDNFVKLLPSDFE 333
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Match: tmprss9 (transmembrane serine protease 9 [Source:Xenbase;Acc:XB-GENE-993973]) HSP 1 Score: 97.4413 bits (241), Expect = 4.191e-21 Identity = 55/169 (32.54%), Postives = 92/169 (54.44%), Query Frame = 3
Query: 93 LIFFLMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+I F + + +DY A H DEL++ GDII + + GW +G L G+ G+FPDNFV+ +K D K N + P T+ ++ + + +S + FSY +N DE+ ++VG+II+VL + +++GWW+G+ G+ G+FPSNF++
Sbjct: 1 MIRFQL--LENFDYKAQHEDELTITAGDIITKIKKEDGGWWEGELKGRRGLFPDNFVRELKKDTKKEQNSKPPDRP---------TQGISNGNALLSSEAVIRSAGRGERTRRRRCQVAFSYLPQNEDELELKVGEIIEVLGE--VEEGWWEGV-LNGKTGMFPSNFIR 155 HSP 2 Score: 62.003 bits (149), Expect = 1.091e-9 Identity = 28/60 (46.67%), Postives = 41/60 (68.33%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFK 287
C + Y A + DEL+++ GDI+ S + GW +G LNGK+GVFPDNFVK++ +DF+
Sbjct: 307 CKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEGELNGKKGVFPDNFVKLLPSDFE 366 HSP 3 Score: 61.2326 bits (147), Expect = 2.000e-9 Identity = 26/54 (48.15%), Postives = 38/54 (70.37%), Query Frame = 3
Query: 438 VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+ +F Y+A N DE+TI GDI+ VL+K +D GWW+G + G+ G+FP NFV+
Sbjct: 307 CKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEG-ELNGKKGVFPDNFVK 359 HSP 4 Score: 55.0694 bits (131), Expect = 1.697e-7 Identity = 25/56 (44.64%), Postives = 35/56 (62.50%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTD 281
C + Y + DEL LK G+II+ + E GW +G LNGK G+FP NF++ I T+
Sbjct: 105 CQVAFSYLPQNEDELELKVGEIIEVLGEVEEGWWEGVLNGKTGMFPSNFIREIVTE 160
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Match: tmprss9 (transmembrane serine protease 9 [Source:Xenbase;Acc:XB-GENE-993973]) HSP 1 Score: 95.5153 bits (236), Expect = 1.519e-20 Identity = 68/216 (31.48%), Postives = 100/216 (46.30%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVK-------------VIKTDFKNTSNKEN--------GTNPNVEDNLNTKT---------------KLKTHSSDQKT------KTTKEKSHINNSLNEPLIVE------------AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
C + Y + DEL LK G+II+ + E GW +G LNGK G+FP NF++ IKT FK+T+ E+ GTN +K KL+ S + ++ K +K + EP+ +E +F Y+A N DE+TI GDI+ VL+K +D GWW+G + G+ G+FP NFV+
Sbjct: 41 CQVAFSYLPQNEDELELKVGEIIEVLGEVEEGWWEGVLNGKTGMFPSNFIREIVTETEIGNFEQQIKTAFKDTTGSESDGGDSKLEGTNGTSGGETQSKRIRGFGFGDIFKDKPIKLRPRSIEMESEIVPIEKAMGKKMPPTVTSQEPMKIETESKTKRKEYCKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEG-ELNGKKGVFPDNFVK 255 HSP 2 Score: 62.003 bits (149), Expect = 8.591e-10 Identity = 28/60 (46.67%), Postives = 41/60 (68.33%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFK 287
C + Y A + DEL+++ GDI+ S + GW +G LNGK+GVFPDNFVK++ +DF+
Sbjct: 203 CKVLFPYEAMNEDELTIRDGDIVTVLSKECVDAGWWEGELNGKKGVFPDNFVKLLPSDFE 262
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Match: lrrc10 (leucine rich repeat containing 10 [Source:Xenbase;Acc:XB-GENE-5959561]) HSP 1 Score: 91.6633 bits (226), Expect = 1.029e-19 Identity = 62/197 (31.47%), Postives = 106/197 (53.81%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSV-IFFETGWKKGWLNGKEGVFPDNFVKVIK-------TDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQP--FSENGSPLSFKKKSSNDSDLSI 668
++ I EYDY A + DEL+++ GD+IK+V E GW +G +NGK G FPDNFVK IK N NK G V + L+ + + + ++S + ++ Y +N DE+ ++VG+++ ++ + +++GWW G +G+ G+FPSNFV+ S++G ++S+ DS+ S+
Sbjct: 1 VEYIVEYDYDAVNEDELTIRVGDVIKNVNKLEEDGWLEGEVNGKRGAFPDNFVKEIKEHPGPKAAKVSNCRNKSGGCTELV--ACIKRYLLRATNPPRLPRPLNKESKKRQ-------CKVLYEYIPQNEDELELKVGEVLDIIEE--VEEGWWSG-SNSGKSGLFPSNFVKEIDLSDDGE----SQESTEDSEPSV 181 HSP 2 Score: 61.2326 bits (147), Expect = 1.116e-9 Identity = 31/56 (55.36%), Postives = 39/56 (69.64%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIK 275
C A ++Y + + DELS K+GDII S + GW KG LNGKEGVFPDNFV +I+
Sbjct: 278 CKALFNYESVNEDELSFKEGDIIHLTSKETGDPGWWKGELNGKEGVFPDNFVAIIQ 333 HSP 3 Score: 55.0694 bits (131), Expect = 9.970e-8 Identity = 31/81 (38.27%), Postives = 46/81 (56.79%), Query Frame = 3
Query: 354 LKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
L++ SSD T K I +A+F+Y++ N DE++ + GDII + +K D GWWKG + G+ G+FP NFV
Sbjct: 256 LRSTSSDASRTETDSKPKAKE------ICKALFNYESVNEDELSFKEGDIIHLTSKETGDPGWWKG-ELNGKEGVFPDNFV 329
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Match: Sh3kbp1 (SH3-domain kinase binding protein 1 [Source:MGI Symbol;Acc:MGI:1889583]) HSP 1 Score: 105.145 bits (261), Expect = 8.646e-24 Identity = 69/211 (32.70%), Postives = 115/211 (54.50%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKN--TSNK--ENGTNPNVEDN--LNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPS 719
+++ I E+DY A H DEL++ G++I ++ + GW +G +NG+ G+FPDNFV+ IK D K SNK E + N L+++T L+T+ ++ + + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS E + L + +P P+
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRR---------------CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLSKSRPEGF-LPASLLPFPA 188 HSP 2 Score: 63.1586 bits (152), Expect = 2.928e-10 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 368 HSP 3 Score: 63.1586 bits (152), Expect = 3.648e-10 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ +DF N+
Sbjct: 316 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGNR 380
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Match: Sh3kbp1 (SH3-domain kinase binding protein 1 [Source:MGI Symbol;Acc:MGI:1889583]) HSP 1 Score: 103.99 bits (258), Expect = 1.764e-23 Identity = 65/206 (31.55%), Postives = 108/206 (52.43%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDN------LNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENS 704
+++ I E+DY A H DEL++ G++I ++ + GW +G +NG+ G+FPDNFV+ IK D K + D L+++T L+T+ ++ + + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS K SL E +
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRR---------------CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLS-----KSSLRETT 179 HSP 2 Score: 63.5438 bits (153), Expect = 2.575e-10 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 275 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 324 HSP 3 Score: 63.5438 bits (153), Expect = 2.691e-10 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ +DF N+
Sbjct: 272 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGNR 336
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Match: Sh3d21 (SH3 domain containing 21 [Source:MGI Symbol;Acc:MGI:1914188]) HSP 1 Score: 101.679 bits (252), Expect = 1.125e-22 Identity = 54/163 (33.13%), Postives = 85/163 (52.15%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQP 602
C ++YS ADEL+L+ G+I++ + E GW G NG+ G FP NFV+++ + + N + P + N KL + D + +++ P +F Y+ E PDE+ ++ GD++KVL K D GWW+G + G G+FP NFV P
Sbjct: 88 CRVNFNYSPEQADELTLQTGEILEVIKEIEDGWWLGEKNGQLGAFPSNFVELLDSGPPSLGNTD---IPPITPNSQRPPKLSNLTYDSPPDYLR-------TVSCPETCRVLFDYQPEAPDELALQKGDLVKVLRKTTEDKGWWEG-ECQGRRGVFPDNFVIP 239 HSP 2 Score: 81.6481 bits (200), Expect = 4.383e-16 Identity = 50/173 (28.90%), Postives = 78/173 (45.09%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFET-GWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSP 623
M+ + Y A DELSL GD+I+ V GW G L G+ G FP V+ I + + + + H NS + F+Y E DE+T++ G+I++V+ + I+DGWW G ++ G++G FPSNFV+ ++G P
Sbjct: 1 MEVLVLARYRAQTEDELSLAPGDVIRQVCAGPARGWLLGELRGRRGRFPKRLVQEIPEALRGVTESRP------------------------RFPRRSRRHPINSRDPQRWCRVNFNYSPEQADELTLQTGEILEVIKE--IEDGWWLG-EKNGQLGAFPSNFVE-LLDSGPP 145
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Match: Cd2ap (CD2-associated protein [Source:MGI Symbol;Acc:MGI:1330281]) HSP 1 Score: 99.3673 bits (246), Expect = 5.306e-22 Identity = 58/169 (34.32%), Postives = 94/169 (55.62%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVI-FFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKT---KLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++D I EYDY A H DEL+++ G+II++V E GW +G LNG+ G+FPDNFVK IK + T K++ E N + ++ T+ ++ + + +F Y +N DE+ + VGD+I V+ + +++GWW G ++G+FPSNFV+
Sbjct: 1 MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIK---RETEPKDDNLPIKRERQGNVASLVQRISTYGLPAGGIQPHPQTKAIKKKTKKRQCKVLFDYSPQNEDELELIVGDVIDVIEE--VEEGWWSGT-LNNKLGLFPSNFVK 163 HSP 2 Score: 77.7962 bits (190), Expect = 6.644e-15 Identity = 66/219 (30.14%), Postives = 93/219 (42.47%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK-TDFKNTSNKE------------------NGTNPNVEDNLNTK---------------TKLKTHSSDQKTKTTK-EKSHI---------NNSLNEPLI---------VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSE 611
C +DYS + DEL L GD+I + E GW G LN K G+FP NFVK ++ T+ T N + NG+ P K KL+T +S +T+ K EK I N + +P + +F Y N DE+T G+II +++K + GWWKG + G+ G+FP NF SE
Sbjct: 113 CKVLFDYSPQNEDELELIVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTEDGETHNAQEESEVPLTGPTSPLPSPGNGSEPAPGSVAQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKTEKPLILQPLGSRTQNVEVTKPDVDGKIKAKEYCRTLFPYTGTNEDELTFREGEIIHLISKETGEAGWWKG-ELNGKEGVFPDNFAVQISE 330
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Match: Grb2 (growth factor receptor bound protein 2 [Source:MGI Symbol;Acc:MGI:95805]) HSP 1 Score: 78.5666 bits (192), Expect = 9.158e-17 Identity = 54/179 (30.17%), Postives = 86/179 (48.04%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSV-IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK----ENGTNPNVE-----DNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSEN 614
M+ IA+YD+ AT DELS K+GDI+K + + W K LNGK+G P N++++ F N +G ++LN +S + + + I +P V+A+F + + E+ GD I V++ + D WWKG G+ G+FP N+V P + N
Sbjct: 1 MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRD-IEQMPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNS--DPNWWKGACH-GQTGMFPRNYVTPVNRN 175
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q8R550|SH3K1_MOUSE (SH3 domain-containing kinase-binding protein 1 OS=Mus musculus OX=10090 GN=Sh3kbp1 PE=1 SV=1) HSP 1 Score: 105.145 bits (261), Expect = 6.048e-23 Identity = 69/211 (32.70%), Postives = 115/211 (54.50%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKN--TSNK--ENGTNPNVEDN--LNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPS 719
+++ I E+DY A H DEL++ G++I ++ + GW +G +NG+ G+FPDNFV+ IK D K SNK E + N L+++T L+T+ ++ + + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS E + L + +P P+
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDMKKDLLSNKAPEKPMHDVSSGNALLSSETILRTNKRGERRRRR---------------CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLSKSRPEGF-LPASLLPFPA 188 HSP 2 Score: 63.1586 bits (152), Expect = 2.048e-9 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 368 HSP 3 Score: 63.1586 bits (152), Expect = 2.552e-9 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ +DF N+
Sbjct: 316 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGNR 380
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q925Q9|SH3K1_RAT (SH3 domain-containing kinase-binding protein 1 OS=Rattus norvegicus OX=10116 GN=Sh3kbp1 PE=1 SV=2) HSP 1 Score: 105.145 bits (261), Expect = 6.390e-23 Identity = 66/205 (32.20%), Postives = 108/205 (52.68%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPS 719
+++ I E+DY A H DEL++ G++I ++ + GW +G +NG+ G+FPDNFV+ IK D K + D + + L SS+ +T K + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS E + L + +P P+
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKDVKKDLLSNKAPEKPMHDVSSGNSLL---SSETILRTNKRGERRRRR------CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLSKSRPEGF-LPASLLPFPA 188 HSP 2 Score: 63.5438 bits (153), Expect = 1.995e-9 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 368 HSP 3 Score: 63.1586 bits (152), Expect = 2.575e-9 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ +DF N+
Sbjct: 316 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPSDFDKEGNR 380
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q96B97|SH3K1_HUMAN (SH3 domain-containing kinase-binding protein 1 OS=Homo sapiens OX=9606 GN=SH3KBP1 PE=1 SV=2) HSP 1 Score: 104.76 bits (260), Expect = 7.869e-23 Identity = 67/200 (33.50%), Postives = 107/200 (53.50%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENS 704
+++ I E+DY A H DEL++ G+II ++ + GW +G +NG+ G+FPDNFV+ IK + K K+ TN E L+ + S + T ++ + FSY +N DE+ ++VGDII+V+ + +++GWW+G+ G+ G+FPSNF++ S L S D LS K SL E +
Sbjct: 1 MVEAIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIKKEMK----KDPLTNKAPEKPLHEVPSGNSLLSSETILRTNKRGERRRRR-----CQVAFSYLPQNDDELELKVGDIIEVVGE--VEEGWWEGV-LNGKTGMFPSNFIKELSGESDELGI----SQDEQLS-----KSSLRETT 179 HSP 2 Score: 63.1586 bits (152), Expect = 2.002e-9 Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSV--IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C + Y A + DEL++K+GDI+ + + GW +G LNG+ GVFPDNFVK++ DF+ N+
Sbjct: 272 CKVIFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKLLPPDFEKEGNR 336 HSP 3 Score: 63.1586 bits (152), Expect = 2.020e-9 Identity = 27/51 (52.94%), Postives = 39/51 (76.47%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
IF Y+A+N DE+TI+ GDI+ ++NK+ ID GWW+G + G G+FP NFV+
Sbjct: 275 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEG-ELNGRRGVFPDNFVK 324
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Match: sp|F1LRS8|CD2AP_RAT (CD2-associated protein OS=Rattus norvegicus OX=10116 GN=Cd2ap PE=1 SV=2) HSP 1 Score: 100.138 bits (248), Expect = 2.504e-21 Identity = 58/169 (34.32%), Postives = 94/169 (55.62%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVI-FFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKT---KLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++D I EYDY A H DEL+++ G+II++V E GW +G LNG+ G+FPDNFVK IK + T K++ E N + ++ T+ ++ + + +F Y +N DE+ + VGD+I V+ + +++GWW G ++G+FPSNFV+
Sbjct: 1 MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIK---RETEPKDDNLPIKRERPGNVASLVQRISTYGLPAGGIQPHPQTKAMKKKTKKRQCKVLFEYSPQNEDELELTVGDVIDVIEE--VEEGWWSGT-LNNKLGLFPSNFVK 163 HSP 2 Score: 77.0258 bits (188), Expect = 9.330e-14 Identity = 66/219 (30.14%), Postives = 94/219 (42.92%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKT-------DFKNTS------------NKENGTNPNVEDNLNTK---------------TKLKTHSSDQKTKTTK-EKSHINNSLN---------EPLI---------VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSE 611
C ++YS + DEL L GD+I + E GW G LN K G+FP NFVK +++ D + S + NG+ P K KL+T +S +T+ K EK I SL +P I + +F Y N DE+T G+II +++K + GWWKG + G+ G+FP NF SE
Sbjct: 113 CKVLFEYSPQNEDELELTVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTDDGEMHDAQEESEVSLTGPTSPMPSPGNGSEPAPGSVTQPKKIRGVGFGDIFKEGSVKLRTRTSSSETEEKKSEKPLILQSLGSRTQNVEVTKPDIDGKIKAKEYCKTVFPYTGTNEDELTFREGEIIHLISKETGEAGWWKG-ELNGKEGVFPDNFAVQISE 330
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Match: sp|Q9JLQ0|CD2AP_MOUSE (CD2-associated protein OS=Mus musculus OX=10090 GN=Cd2ap PE=1 SV=3) HSP 1 Score: 99.3673 bits (246), Expect = 3.711e-21 Identity = 58/169 (34.32%), Postives = 94/169 (55.62%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVI-FFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKT---KLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++D I EYDY A H DEL+++ G+II++V E GW +G LNG+ G+FPDNFVK IK + T K++ E N + ++ T+ ++ + + +F Y +N DE+ + VGD+I V+ + +++GWW G ++G+FPSNFV+
Sbjct: 1 MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIK---RETEPKDDNLPIKRERQGNVASLVQRISTYGLPAGGIQPHPQTKAIKKKTKKRQCKVLFDYSPQNEDELELIVGDVIDVIEE--VEEGWWSGT-LNNKLGLFPSNFVK 163 HSP 2 Score: 77.7962 bits (190), Expect = 4.647e-14 Identity = 66/219 (30.14%), Postives = 93/219 (42.47%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK-TDFKNTSNKE------------------NGTNPNVEDNLNTK---------------TKLKTHSSDQKTKTTK-EKSHI---------NNSLNEPLI---------VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSE 611
C +DYS + DEL L GD+I + E GW G LN K G+FP NFVK ++ T+ T N + NG+ P K KL+T +S +T+ K EK I N + +P + +F Y N DE+T G+II +++K + GWWKG + G+ G+FP NF SE
Sbjct: 113 CKVLFDYSPQNEDELELIVGDVIDVIEEVEEGWWSGTLNNKLGLFPSNFVKELESTEDGETHNAQEESEVPLTGPTSPLPSPGNGSEPAPGSVAQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKTEKPLILQPLGSRTQNVEVTKPDVDGKIKAKEYCRTLFPYTGTNEDELTFREGEIIHLISKETGEAGWWKG-ELNGKEGVFPDNFAVQISE 330
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Match: A0A0R3SVD8 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS9530 PE=4 SV=1) HSP 1 Score: 125.561 bits (314), Expect = 2.944e-28 Identity = 83/241 (34.44%), Postives = 130/241 (53.94%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQK-TKTTKEKSHINNSLNEPL--------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIK-RTGEIGIFPSNFVQPFSENGSPLSFKK-----KSSNDSDLSIKNVEKYSLN-----ENSIPSPSVS-FNDLSNGK 749
M+ EYDY+A DEL+LK+GDI+ +V FE GW G NG+EGVFPDNFV++IK+ + ++ + +++ + T + + SS + +T + + N + P V+A + Y E PDE+ +EV D I+VL+++L +DGWW G RT + G FP+NFV+ ++ P FK+ K+ S S + + SL+ +N+ SP S + DLS GK
Sbjct: 1 MEVEVEYDYTAEERDELTLKRGDIVTNVSQFEEGWYIGTFNGREGVFPDNFVRIIKSAPGKANQPKSSEKLDSQNDRSRSTPVSSPSSALRGNRTDRVVENGKNQVASPTPTTPATSISTKASDYVKADYPYTQEQPDELELEVNDFIRVLSRDLPEDGWWHGTNLRTNKTGFFPNNFVK-MADANDP-DFKRIIANLKAKAASSPSPQRTQNGSLSTAKTPQNNPASPHGSRYYDLSGGK 239
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Match: A0A5K4F7S5 (Uncharacterized protein OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 127.872 bits (320), Expect = 2.992e-28 Identity = 83/208 (39.90%), Postives = 115/208 (55.29%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIK-RTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPSVSF 728
M+ I EYDY+A DEL++KKGDII+ V FE GW G LNG+ GVFPDNFVKV S + G+N +V + +K+ ++ N N+ V A + Y + DE+ + + DII+VL++NL DDGWW+G RT IGIFP NFV P NG+ K ++S L +YS N +++P+ SVS
Sbjct: 1 MEVIVEYDYTAEENDELTIKKGDIIRDVSQFEEGWYIGCLNGRIGVFPDNFVKV------KASVQSKGSNVSVPERAIGNSKILDDTAS------------NYPTNQ---VRARYEYIPKQADELELHIDDIIQVLDRNLPDDGWWRGRNMRTNLIGIFPDNFVAPI--NGT-----NKELDESKL------QYSRNLSNVPNKSVSV 174
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Match: A0A068Y967 (Cbl interacting protein of 85 kDa OS=Echinococcus multilocularis OX=6211 PE=4 SV=1) HSP 1 Score: 126.716 bits (317), Expect = 3.963e-28 Identity = 69/178 (38.76%), Postives = 104/178 (58.43%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIK-RTGEIGIFPSNFVQPFSENGSPLSFKK 638
M+ EYDY+A DEL+LK+GDI+ +V FE GW G NG+EGVFPDNFV++IK P + + KT++ +S +T I+N ++ V+ + Y E DE+ +EV D I+VL+++L +DGWW+GI RT + G+FP NFV+ + + + L FK+
Sbjct: 1 MEVQVEYDYTAEERDELTLKQGDIVTNVSQFEEGWYIGTFNGREGVFPDNFVRIIKPT----------PAPGSQPQESHKTQVPPGASSPLPMSTS----ISNKASD--YVKVAYRYNPEQSDELQLEVKDFIRVLSRDLPEDGWWRGINLRTNKTGVFPDNFVR--TADANDLDFKR 160
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Match: W6V7B0 (SH3 domain-containing kinase-binding protein OS=Echinococcus granulosus OX=6210 GN=EGR_02797 PE=4 SV=1) HSP 1 Score: 125.561 bits (314), Expect = 6.602e-28 Identity = 69/178 (38.76%), Postives = 101/178 (56.74%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIK-RTGEIGIFPSNFVQPFSENGSPLSFKK 638
M+ EYDY+A DEL+LK+GDI+ +V FE GW G NG+EGVFPDNFV++IK P + + KT++ S +T I+N ++ V+ + Y E DE+ +EV D I+VL+++L +DGWW+G+ RT + G+FP NFV+ N L FK+
Sbjct: 1 MEVQVEYDYTAEERDELTLKQGDIVTNVSQFEEGWYIGTFNGREGVFPDNFVRIIKP----------APAPGSQPQESHKTQVPLGVSSPLPMSTS----ISNKASD--YVKVAYRYNPEQSDELQLEVKDFIRVLSRDLPEDGWWRGVNLRTNKTGVFPDNFVRTADAND--LDFKR 160
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Match: A0A564Y6C3 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS3522 PE=4 SV=1) HSP 1 Score: 125.561 bits (314), Expect = 8.492e-28 Identity = 83/241 (34.44%), Postives = 130/241 (53.94%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQK-TKTTKEKSHINNSLNEPL--------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIK-RTGEIGIFPSNFVQPFSENGSPLSFKK-----KSSNDSDLSIKNVEKYSLN-----ENSIPSPSVS-FNDLSNGK 749
M+ EYDY+A DEL+LK+GDI+ +V FE GW G NG+EGVFPDNFV++IK+ + ++ + +++ + T + + SS + +T + + N + P V+A + Y E PDE+ +EV D I+VL+++L +DGWW G RT + G FP+NFV+ ++ P FK+ K+ S S + + SL+ +N+ SP S + DLS GK
Sbjct: 1 MEVEVEYDYTAEERDELTLKRGDIVTNVSQFEEGWYIGTFNGREGVFPDNFVRIIKSAPGKANQPKSSEKLDSQNDRSRSTPVSSPSSALRGNRTDRVVENGKNQVASPTPTTPATSISTKASDYVKADYPYTQEQPDELELEVNDFIRVLSRDLPEDGWWHGTNLRTNKTGFFPNNFVK-MADANDP-DFKRIIANLKAKAASSPSPQRTQNGSLSTAKTPQNNPASPHGSRYYDLSGGK 239
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Match: sh3kbp1 (SH3-domain kinase binding protein 1 [Source:ZFIN;Acc:ZDB-GENE-091204-186]) HSP 1 Score: 106.686 bits (265), Expect = 1.971e-24 Identity = 59/172 (34.30%), Postives = 98/172 (56.98%), Query Frame = 3
Query: 84 FPFLIFFLMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
F + F ++ I E+DY A H DEL++ G+II ++ E GW +G ++G+ G+FPDNFV+ IK + K ++ + T D N T + SD + K+ I +A FSY +N DE+ +++GD+I +L + +++GWW+G +G+ G+FPSNF +
Sbjct: 11 FSISLSFSVEAIVEFDYQAQHDDELTISVGEIISNIRKDEGGWWEGEVDGRRGLFPDNFVREIKKEVKKEASLASQTAGPKSDLSNGST---SPGSDSCLRPAKKGDAIRKRR-----CKAAFSYIPQNEDELELKIGDVIDILGE--VEEGWWEG-SLSGKTGMFPSNFTK 171 HSP 2 Score: 57.3806 bits (137), Expect = 1.497e-8 Identity = 26/69 (37.68%), Postives = 42/69 (60.87%), Query Frame = 3
Query: 399 KSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPF 605
K+ +N + +F Y A+N DE++I+ G+I+ ++NK D GWW G + G+ G+FP NFV+ F
Sbjct: 273 KTEPDNKARAKEFCKVLFPYDAQNEDELSIKEGEIVTIINKECADAGWWLG-ELNGKQGVFPDNFVKLF 340 HSP 3 Score: 55.0694 bits (131), Expect = 8.933e-8 Identity = 27/55 (49.09%), Postives = 38/55 (69.09%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVI---FFETGWKKGWLNGKEGVFPDNFVKV 269
C + Y A + DELS+K+G+I+ ++I + GW G LNGK+GVFPDNFVK+
Sbjct: 286 CKVLFPYDAQNEDELSIKEGEIV-TIINKECADAGWWLGELNGKQGVFPDNFVKL 339
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Match: sh3d21 (SH3 domain containing 21 [Source:NCBI gene;Acc:103034682]) HSP 1 Score: 90.1225 bits (222), Expect = 3.970e-19 Identity = 53/165 (32.12%), Postives = 82/165 (49.70%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSV-IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
M+ + D+ T DELS++ GD++K+V E GW +G L GK G+FP NFVK + S +E + ++T K K E ++Y +N DE+ + VG+ +++L + I+DGWW G K+ +IG FPSNFV+
Sbjct: 1 MEVLVLIDFEGTLGDELSVQAGDVVKNVKAASEDGWLEGELRGKRGIFPSNFVKEVPVHLMGDSKREPRS-------------MRTSKMPLKDLCRK--------------CEVTYTYMPQNEDELDLAVGETVEILRE--IEDGWWMG-KKNNKIGAFPSNFVK 135 HSP 2 Score: 88.5817 bits (218), Expect = 1.205e-18 Identity = 55/161 (34.16%), Postives = 79/161 (49.07%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
C Y Y + DEL L G+ ++ + E GW G N K G FP NFVK I K+ E+ + P + D+L TK + +S +K KE + +F Y A DE+ ++ GDI+ +++K DDGWW+G + G G FP NFV
Sbjct: 85 CEVTYTYMPQNEDELDLAVGETVEILREIEDGWWMGKKNNKIGAFPSNFVKEIFP--KDGLQHESKSRPKLSDSLFTKEAPQQRASIRKKTNVKE------------CCQVMFDYTAVAEDELNLKKGDIVTIISKASEDDGWWEG-ELNGRRGFFPDNFV 230 HSP 3 Score: 62.003 bits (149), Expect = 4.903e-10 Identity = 30/58 (51.72%), Postives = 37/58 (63.79%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVIKTD 281
C +DY+A DEL+LKKGDI+ S + GW +G LNG+ G FPDNFV VI D
Sbjct: 179 CQVMFDYTAVAEDELNLKKGDIVTIISKASEDDGWWEGELNGRRGFFPDNFVMVIPMD 236
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Match: cd2ap (CD2 associated protein [Source:NCBI gene;Acc:103029908]) HSP 1 Score: 82.0333 bits (201), Expect = 2.009e-16 Identity = 65/224 (29.02%), Postives = 106/224 (47.32%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK-------------TDFKNTSNKENGTNPN------------------VEDNLNTKTKLKTHSSDQKTK------TTKEKSHINNSLNEPL------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSE-NGSPLSFK 635
C ++Y + DEL LK GDII+ E GW G +NGK G+FP NFVK ++ D K+ + +P D++ K +L + + D+K K + + ++++ S + L +A F+Y+A N DE+ I+ GD+I +L+K+ + GWW+G + +G+ G+FP NFV SE + PL+ K
Sbjct: 136 CKVVFEYVPQNEDELELKVGDIIEITEEVEEGWWSGSMNGKSGLFPSNFVKEVEMNEEEEISDVPDDPDSKDEAMSPTSPHPGNGVIAQPKKVKGVGFGDIFRDSVKLKVRLPSETEDKKEKPIPSLPSAAKPTNLSTSDAQKLEKDGESKGKVKEYCKATFAYEATNQDELDIKEGDVIHLLSKDTGEPGWWRG-ELSGKQGVFPDNFVVLLSESDKEPLASK 358 HSP 2 Score: 71.2478 bits (173), Expect = 7.543e-13 Identity = 54/178 (30.34%), Postives = 86/178 (48.31%), Query Frame = 3
Query: 138 ATHADELSLKKGDIIKSVIFFET-GWKKGWLNGKEGVFPDNFVK-----VIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINN------------------SLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
A H DEL+L++GDIIK+V E GW +G LNG+ G+FPDNFVK +K + K + + ++K ++ Q+ S + + + +F Y +N DE+ ++VGDII++ + ++GWW G G+ G+FPSNFV+
Sbjct: 12 AAHEDELTLRQGDIIKNVRRIEEEGWMEGDLNGRRGLFPDNFVKEVRKEPVKEEVKEAKEVKEAKETKEVKEVKEVKEVKENAQPQRRSAGNVASLVQRISTYGIPTGGLGFQPRSSKKKKKRQCKVVFEYVPQNEDELELKVGDIIEITEEV--EEGWWSG-SMNGKSGLFPSNFVK 186
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Match: cd2ap (CD2 associated protein [Source:NCBI gene;Acc:103029908]) HSP 1 Score: 82.0333 bits (201), Expect = 2.494e-16 Identity = 62/216 (28.70%), Postives = 102/216 (47.22%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK-------------TDFKNTSNKENGTNPN------------------VEDNLNTKTKLKTHSSDQKTK------TTKEKSHINNSLNEPL------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSEN 614
C ++Y + DEL LK GDII+ E GW G +NGK G+FP NFVK ++ D K+ + +P D++ K +L + + D+K K + + ++++ S + L +A F+Y+A N DE+ I+ GD+I +L+K+ + GWW+G + +G+ G+FP NFV SE+
Sbjct: 100 CKVVFEYVPQNEDELELKVGDIIEITEEVEEGWWSGSMNGKSGLFPSNFVKEVEMNEEEEISDVPDDPDSKDEAMSPTSPHPGNGVIAQPKKVKGVGFGDIFRDSVKLKVRLPSETEDKKEKPIPSLPSAAKPTNLSTSDAQKLEKDGESKGKVKEYCKATFAYEATNQDELDIKEGDVIHLLSKDTGEPGWWRG-ELSGKQGVFPDNFVVLLSES 314 HSP 2 Score: 75.485 bits (184), Expect = 3.077e-14 Identity = 55/155 (35.48%), Postives = 85/155 (54.84%), Query Frame = 3
Query: 138 ATHADELSLKKGDIIKSVIFF-ETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
A H DEL+L++GDIIK+V E GW +G LNG+ G+FPDNFVK + KE + NV + ++ T+ + +S + + +F Y +N DE+ ++VGDII++ + ++GWW G G+ G+FPSNFV+
Sbjct: 12 AAHEDELTLRQGDIIKNVRRIEEEGWMEGDLNGRRGLFPDNFVKTKEV-------KERRSAGNVASLVQ---RISTYGIPTGGLGFQPRSSKKKKKRQ---CKVVFEYVPQNEDELELKVGDIIEITEEV--EEGWWSG-SMNGKSGLFPSNFVK 150
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Match: sorbs2a (sorbin and SH3 domain-containing protein 2-like [Source:NCBI gene;Acc:103043954]) HSP 1 Score: 81.2629 bits (199), Expect = 4.572e-16 Identity = 54/174 (31.03%), Postives = 89/174 (51.15%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNG--KEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSD----QKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEI-GIFPSNFVQPF 605
+ + +A Y+++A ELSL+KG+ + + + W +G + G K+G+FP ++V VIK + +K TH D QK K + S ++ EP +A+++Y N DE+ + VGDII+V+ K DDGW+ G R ++ G FP N+V+P
Sbjct: 734 MGEAVARYNFNADTNVELSLRKGERVILLRKVDQNWFEGRIPGSSKQGIFPVSYVDVIK---------------------GSPSKSPTHHGDTHRGQKVKRMMQDS--SHGSGEPF--QAVYNYVPRNEDELELRVGDIIEVMEK--CDDGWFVGTSRRSKMFGTFPGNYVKPL 880
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Match: dnmbp (dynamin binding protein [Source:NCBI gene;Acc:100005174]) HSP 1 Score: 60.4622 bits (145), Expect = 4.475e-10 Identity = 70/237 (29.54%), Postives = 107/237 (45.15%), Query Frame = 3
Query: 135 SATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKE---KSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPSVSFNDLSNGKMKHFSTNSYLINNSKVLKATKNINVSSTS 836
+A EL ++GDII E GW G ++G+ G FP+ FV+++K K NV+D+ + L SDQ T E S N NE V A++ +KA E+ G+ I ++ + ++D W +G R GIFP FV+ GSP+S + +SD ++ +K EN+ S SF+ K +N L NN + + NI +S S
Sbjct: 160 AAQMEGELDFREGDIITITGIPEEGWYDGEIDGRRGTFPEGFVELLKPLKKM----------NVKDHCQDEEIL---DSDQSTLCGSEYGPHSQHNVDANEMYAV-ALYDFKAIEAGELDFRKGERITIIQE--LEDDWLEGEVRDCR-GIFPIRFVK-LETKGSPVS-DLVQTMESDPNLNRSKK----ENTSFKQSKSFDVYQ----KELPSN-LLENNEDLSCNSSNIEISVVS 368
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008112.1 (pep scaffold:Pmarinus_7.0:GL482163:8897:24902:-1 gene:ENSPMAG00000007333.1 transcript:ENSPMAT00000008112.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 57.3806 bits (137), Expect = 8.848e-10 Identity = 27/65 (41.54%), Postives = 42/65 (64.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVI--FFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNK 302
C A + Y A + DELSLK+G++++ + + GW +G +NGK GVFPDNFVK++ + + K
Sbjct: 5 CKALFSYEAQNNDELSLKEGELVEIIAKDCGDAGWWEGEVNGKRGVFPDNFVKLLPAEVEKEYEK 69 HSP 2 Score: 55.8398 bits (133), Expect = 2.730e-9 Identity = 22/52 (42.31%), Postives = 41/52 (78.85%), Query Frame = 3
Query: 444 AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
A+FSY+A+N DE++++ G++++++ K+ D GWW+G + G+ G+FP NFV+
Sbjct: 7 ALFSYEAQNNDELSLKEGELVEIIAKDCGDAGWWEG-EVNGKRGVFPDNFVK 57
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Match: nebl (nebulette [Source:ZFIN;Acc:ZDB-GENE-050320-151]) HSP 1 Score: 53.9138 bits (128), Expect = 1.617e-8 Identity = 22/55 (40.00%), Postives = 37/55 (67.27%), Query Frame = 3
Query: 444 AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKG-IKRTGEIGIFPSNFVQPF 605
A++ Y A + DE++ GD+I+ N ID+GW G ++RTG+ G+ P+N++QP
Sbjct: 200 AVYDYAAADDDEVSFLDGDVIE--NVKQIDEGWMYGTVQRTGQTGMLPANYLQPL 252
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Match: DBNL (drebrin like [Source:HGNC Symbol;Acc:HGNC:2696]) HSP 1 Score: 54.299 bits (129), Expect = 1.933e-8 Identity = 27/74 (36.49%), Postives = 42/74 (56.76%), Query Frame = 3
Query: 384 KTTKEKSHINNSLNEPL--IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+ +E H N+ +E L A++ Y+A + EI+ + GD+I N IDDGWW G G G+FP+N+V+
Sbjct: 282 REEEEPDHGGNAKSEGLGQCARALYDYQAADDTEISFDPGDLIS--NIEQIDDGWWNGSGPDGSRGMFPANYVE 353
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Match: sorbs1 (sorbin and SH3 domain containing 1 [Source:ZFIN;Acc:ZDB-GENE-090313-168]) HSP 1 Score: 53.9138 bits (128), Expect = 4.229e-8 Identity = 24/54 (44.44%), Postives = 38/54 (70.37%), Query Frame = 3
Query: 441 EAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGI-KRTGEIGIFPSNFVQ 599
+AI++YK +N DE+ + VGD+++V+ K DDGW+ G +RT G FP N+V+
Sbjct: 587 QAIYNYKPQNEDELELLVGDVVEVMEK--CDDGWFVGTSRRTRLFGTFPGNYVK 638
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Yeast
Match: LSB1 (Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication [Source:SGD;Acc:S000003368]) HSP 1 Score: 52.373 bits (124), Expect = 2.699e-8 Identity = 32/95 (33.68%), Postives = 57/95 (60.00%), Query Frame = 3
Query: 438 VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQP-FSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPS 719
VEA++ ++A+ +++++ GD I+VL K I W++G K +IGIFP+N+V+P F+ + SP S + SS+ +++ S+P PS
Sbjct: 58 VEALYDFEAQQDGDLSLKTGDKIQVLEK--ISPDWYRG-KSNNKIGIFPANYVKPAFTRSASPKSAEAASSS------------TVSRPSVPPPS 137
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Yeast
Match: HSE1 (Subunit of the endosomal Vps27p-Hse1p complex; complex is required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes [Source:SGD;Acc:S000000994]) HSP 1 Score: 51.9878 bits (123), Expect = 8.801e-8 Identity = 24/56 (42.86%), Postives = 32/56 (57.14%), Query Frame = 3
Query: 438 VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPF 605
V A++ PDE++ GD+I VL + D WWKG R G +GIFP N+V P
Sbjct: 222 VRALYDLTTNEPDELSFRKGDVITVLEQVYRD--WWKGALR-GNMGIFPLNYVTPI 274 HSP 2 Score: 47.3654 bits (111), Expect = 3.008e-6 Identity = 22/51 (43.14%), Postives = 28/51 (54.90%), Query Frame = 3
Query: 120 AEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVI 272
A YD + DELS +KGD+I + W KG L G G+FP N+V I
Sbjct: 224 ALYDLTTNEPDELSFRKGDVITVLEQVYRDWWKGALRGNMGIFPLNYVTPI 274
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Yeast
Match: BZZ1 (SH3 domain protein implicated in regulating actin polymerization; able to recruit actin polymerization machinery through its SH3 domains; colocalizes with cortical actin patches and Las17p; interacts with type I myosins [Source:SGD;Acc:S000001156]) HSP 1 Score: 47.3654 bits (111), Expect = 2.728e-6 Identity = 41/165 (24.85%), Postives = 72/165 (43.64%), Query Frame = 3
Query: 126 YDYSATHADELSLKKGDIIKSVIFFETGWKKGWL------NGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDG-WWKGIKRTGEIGIFPSNFVQ 599
Y Y DE+++ GD I S++ +TG GW G+ G+ P ++++ + + G P V + ++T +EAI++Y+A+ DEI+I+ GDII V+ DDG W + G G+FP+++ +
Sbjct: 502 YAYVQKDDDEITITPGDKI-SLVARDTG--SGWTKINNDTTGETGLVPTTYIRI--SSAATVKANDRGPAPEVPPPRRSTLPVRT-------------------------MEAIYAYEAQGDDEISIDPGDIITVIRG---DDGSGWTYGECDGLKGLFPTSYCK 633
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Yeast
Match: YSC84 (Actin-binding protein; involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p; YSC84 has a paralog, LSB3, that arose from the whole genome duplication [Source:SGD;Acc:S000001058]) HSP 1 Score: 46.595 bits (109), Expect = 4.394e-6 Identity = 18/52 (34.62%), Postives = 34/52 (65.38%), Query Frame = 3
Query: 444 AIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
A++++ E P ++ + GD+I +L K+ + WW G + G+ GIFP+N+V+
Sbjct: 416 ALYNFAGEQPGDLAFKKGDVITILKKSDSQNDWWTG-RTNGKEGIFPANYVR 466
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Match: EDO38710 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SC74]) HSP 1 Score: 77.7962 bits (190), Expect = 1.113e-16 Identity = 52/163 (31.90%), Postives = 78/163 (47.85%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLI-VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
C+ +DY A +ADELSL G I + E GW +G ++G++GVFP NFVK+ D T TK K Q EP++ + + Y+ +N DE+ ++VGDII ++ K + D W + G+ G+FP NFV+
Sbjct: 83 CVL-FDYEAENADELSLVTGIEINVIREVEDGWWEGTVDGRKGVFPSNFVKLKPID-------------------ETPTKTKRQPEKQPPA------------EEPVLRAKVTYDYEQQNEDELELKVGDIITIVKKEVFDTPGWMEGELDGKTGLFPDNFVE 213 HSP 2 Score: 72.4034 bits (176), Expect = 9.655e-15 Identity = 54/160 (33.75%), Postives = 82/160 (51.25%), Query Frame = 3
Query: 126 YDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK--TDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
++Y A DELSL+ DII+ ++ + GW +G LNGK+G+FP NFV I+ + ++ K + K KL + SS K +F Y+AEN DE+++ G I V+ + ++DGWW+G G G+FPSNFV+
Sbjct: 1 FEYEAAEPDELSLQIDDIIEDIVDEDVGWARGDLNGKKGLFPVNFVDFIENNAELAKSAGK-----------ASYKRKLLSFSSTDSIAGRK--------------ACVLFDYEAENADELSLVTGIEINVIRE--VEDGWWEGT-VDGRKGVFPSNFVK 132 HSP 3 Score: 55.4546 bits (132), Expect = 5.353e-9 Identity = 27/52 (51.92%), Postives = 35/52 (67.31%), Query Frame = 3
Query: 126 YDYSATHADELSLKKGDIIKSV---IFFETGWKKGWLNGKEGVFPDNFVKVI 272
YDY + DEL LK GDII V +F GW +G L+GK G+FPDNFV+++
Sbjct: 164 YDYEQQNEDELELKVGDIITIVKKEVFDTPGWMEGELDGKTGLFPDNFVEIL 215
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Match: EDO29744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2S0]) HSP 1 Score: 67.3958 bits (163), Expect = 1.372e-12 Identity = 52/175 (29.71%), Postives = 79/175 (45.14%), Query Frame = 3
Query: 96 IFFLMDCIAEY--DYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGK-----EGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+F L IA Y+A AD+LSL G +I+ +GW +G L + G+FP N VK++ K ++G+ T T+ +Q V A+F Y A+ DE+T G + V++K D WWKG + G++G+FPSN+VQ
Sbjct: 65 LFCLFSEIATVVSPYTAIAADQLSLAPGQLIRVTRKDPSGWWEGELQARGKKRQSGIFPANHVKILA---KGPGGSQSGSC--------TSTQQPPEGGNQ--------------------VLAMFPYTAQKGDELTFYKGSVFNVMSK---DGEWWKG-ELNGQVGMFPSNYVQ 204
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Match: EDO38076 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SE08]) HSP 1 Score: 63.1586 bits (152), Expect = 9.710e-12 Identity = 52/195 (26.67%), Postives = 92/195 (47.18%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSV-IFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKT---TKEKSHINN----SLNEPL---------------------IVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKG-IKRTGEIGIFPSNFVQP 602
M+ A++++ AT D+L KG I+ + + + W K +G+EG P ++++ D E G N V L + ++ Q K T K ++ N SLN+ + V+A+F ++A+ E++ + GD I+V++ + D WW+G + TGEIG+FPSN+V+
Sbjct: 1 MEARAKHEFKATQEDDLGFAKGSILNVLDMDQDKNWYKAEQDGREGWIPKTYIEMKPHDV-----GEEGGNHQVVQCLGRGDHQRFNNQVQHFKVFRDTDRKYYLWNTKFLSLNKLVDHHREASVSRSQHIVLKDMMEAVQALFDFEAQEEGEVSFKRGDCIEVIDNS--DVNWWRGKVLTTGEIGMFPSNYVKA 188
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Match: EDO44980 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUA3]) HSP 1 Score: 60.8474 bits (146), Expect = 6.240e-10 Identity = 53/212 (25.00%), Postives = 91/212 (42.92%), Query Frame = 3
Query: 117 IAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV----------------QPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENS 704
+A YSA E+SLKKGD +K + W +G +NG G+FP FV+ + +E +N +NL+ EA++ ++A N DE++ +G I V+ K+ +D+ W++G G+ G+FP ++V +P++ + P + NDS+L+ K E L E +
Sbjct: 115 VAIQSYSAQRPGEISLKKGDFVKVLEEIGNNWLRGDINGTIGIFPCVFVEDCSKPEDSKDGEELYSNFGFYENLDIT-----------------------------FAEALYGFEARNKDELSFPMGAEI-VVTKD-VDNDWYEGTFE-GDTGLFPKSYVRIMDPPVEQSMSDDNKRPYARSIYPFV----AENDSELTFKEGEIIQLRERA 290
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Match: EDO43872 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXM7]) HSP 1 Score: 58.5362 bits (140), Expect = 2.017e-9 Identity = 25/56 (44.64%), Postives = 36/56 (64.29%), Query Frame = 3
Query: 105 LMDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVI 272
L C A YDY AT +DEL++ GDII + GW +G LN ++G+FP ++V+ I
Sbjct: 436 LCQCKAIYDYQATQSDELTIHPGDIITVTARLDNGWWQGDLNNQQGIFPASYVEEI 491 HSP 2 Score: 51.6026 bits (122), Expect = 3.596e-7 Identity = 23/54 (42.59%), Postives = 36/54 (66.67%), Query Frame = 3
Query: 438 VEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
+AI+ Y+A DE+TI GDII V + +D+GWW+G + GIFP+++V+
Sbjct: 439 CKAIYDYQATQSDELTIHPGDIITVTAR--LDNGWWQG-DLNNQQGIFPASYVE 489
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Match: cd2ap (CD2 associated protein [Source:NCBI gene;Acc:101154913]) HSP 1 Score: 104.375 bits (259), Expect = 1.055e-23 Identity = 63/175 (36.00%), Postives = 98/175 (56.00%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFET-GWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSD--QKTKTTKEKSHINNSLNEPLIV--------EAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQ 599
M+ + E+DY A H DEL+L+ GD+I++V + E GW +G LNGK GVFPDNFVK IK + + KE P E ++ K + H ++ Q+ T P V + +F Y+ +N DE+ ++ GD+I++ + +++GWW G G+ G+FPSNFV+
Sbjct: 1 MEVLVEFDYEALHDDELTLRPGDVIRNVRYIEEDGWMEGDLNGKRGVFPDNFVKEIKKEKEPKEVKETKHEPKEETSVPQKREKSAHVANLVQRMSTI---GFPTGGFQPPTTVKKPKKRHCKVLFDYQPQNEDELELKKGDLIEITEE--VEEGWWSG-SLNGKSGLFPSNFVK 169 HSP 2 Score: 62.003 bits (149), Expect = 5.266e-10 Identity = 29/55 (52.73%), Postives = 37/55 (67.27%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIK--SVIFFETGWKKGWLNGKEGVFPDNFVKVI 272
C + + TH DELSLK+GDI++ S ETGW +G + G+ GVFPDNFV VI
Sbjct: 276 CRVMFAFEGTHEDELSLKEGDIVQILSKDTGETGWWRGEIGGERGVFPDNFVVVI 330 HSP 3 Score: 55.0694 bits (131), Expect = 9.708e-8 Identity = 31/99 (31.31%), Postives = 55/99 (55.56%), Query Frame = 3
Query: 447 IFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKK---KSSNDSDLSIKNVEKYSLNENSIPSPSVSFND 734
+F+++ + DE++++ GDI+++L+K+ + GWW+G + GE G+FP NFV SE + KSS +L K + + + P P + F D
Sbjct: 279 MFAFEGTHEDELSLKEGDIVQILSKDTGETGWWRG-EIGGERGVFPDNFVVVISETERESLMSRGSIKSSPKQELDPKRKKPPPPTKATGPRPDIPFTD 376
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Match: sh3d21 (SH3 domain containing 21 [Source:NCBI gene;Acc:101167234]) HSP 1 Score: 81.2629 bits (199), Expect = 2.791e-16 Identity = 53/161 (32.92%), Postives = 76/161 (47.20%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
C + Y + DEL L G+ I+ + E GW G N K G FP NFV I K+ E + P + D + TK + S KT E + +F YKA++ DE+ ++ GD++ +L K D+GWW+G + G G FP NFV
Sbjct: 83 CEVIFPYCPQNDDELELVVGETIEIIREIEDGWWMGVRNAKVGAFPSNFVTEIIFPPKDLKQIEGKSRPKLSDAMFTKEISRKPSVRSHAKTNVEYCQV------------MFDYKAQSEDELDLKKGDVVVLLRKETEDEGWWEG-ELNGRCGFFPDNFV 230 HSP 2 Score: 78.1814 bits (191), Expect = 2.554e-15 Identity = 55/164 (33.54%), Postives = 79/164 (48.17%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFF-ETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
M+ + D+ T DEL++K GD++K+V E GW G L GK G+FP NFVK I S +E S +K K K+ E IF Y +N DE+ + VG+ I+++ + +DGWW G+ R ++G FPSNFV
Sbjct: 1 MEVLVLMDFEGTAGDELTVKTGDVLKNVTKANEEGWLHGELRGKWGIFPVNFVKEIPVYLIGDSKREP-------------------RSIRKPKKVKQVRK----------CEVIFPYCPQNDDELELVVGETIEIIREI--EDGWWMGV-RNAKVGAFPSNFV 132
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Match: ENSORLT00000035709.1 (SH3 domain-containing protein 19 [Source:NCBI gene;Acc:101175352]) HSP 1 Score: 71.633 bits (174), Expect = 6.339e-13 Identity = 47/181 (25.97%), Postives = 88/181 (48.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK--TDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNF--VQPFSENGSPLSFKKKS 644
C+A +DY DEL+ +GD+I W +G ++GK G+FP NF +V++ +S E+G K L+ T++++ +S E +V A+F + + ++++ + G +I+V + +D W +G + G G+FP++F QP + SP+ K+
Sbjct: 708 CVARFDYEGEEDDELTFSRGDVIALQEVMGDEWGRGQIHGKSGIFPLNFTEVLEPLPPAVTSSPGESG-----------KVTLEETPDSALTESSQ------DSEGEEWVV-ALFDFPGQTAEDLSFQKGALIRVTER--VDAEWLRG-RLDGREGLFPASFAQAQPIPDQQSPVGRAAKA 867
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Match: ENSORLT00000027778.1 (SH3 domain-containing protein 19 [Source:NCBI gene;Acc:101175352]) HSP 1 Score: 71.2478 bits (173), Expect = 7.645e-13 Identity = 47/181 (25.97%), Postives = 88/181 (48.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK--TDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNF--VQPFSENGSPLSFKKKS 644
C+A +DY DEL+ +GD+I W +G ++GK G+FP NF +V++ +S E+G K L+ T++++ +S E +V A+F + + ++++ + G +I+V + +D W +G + G G+FP++F QP + SP+ K+
Sbjct: 734 CVARFDYEGEEDDELTFSRGDVIALQEVMGDEWGRGQIHGKSGIFPLNFTEVLEPLPPAVTSSPGESG-----------KVTLEETPDSALTESSQ------DSEGEEWVV-ALFDFPGQTAEDLSFQKGALIRVTER--VDAEWLRG-RLDGREGLFPASFAQAQPIPDQQSPVGRAAKA 893
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Match: ENSORLT00000041735.1 (SH3 domain-containing protein 19 [Source:NCBI gene;Acc:101175352]) HSP 1 Score: 71.2478 bits (173), Expect = 9.144e-13 Identity = 47/181 (25.97%), Postives = 88/181 (48.62%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIK--TDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNF--VQPFSENGSPLSFKKKS 644
C+A +DY DEL+ +GD+I W +G ++GK G+FP NF +V++ +S E+G K L+ T++++ +S E +V A+F + + ++++ + G +I+V + +D W +G + G G+FP++F QP + SP+ K+
Sbjct: 764 CVARFDYEGEEDDELTFSRGDVIALQEVMGDEWGRGQIHGKSGIFPLNFTEVLEPLPPAVTSSPGESG-----------KVTLEETPDSALTESSQ------DSEGEEWVV-ALFDFPGQTAEDLSFQKGALIRVTER--VDAEWLRG-RLDGREGLFPASFAQAQPIPDQQSPVGRAAKA 923
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Match: SMESG000001129.1 (SMESG000001129.1) HSP 1 Score: 705.286 bits (1819), Expect = 0.000e+0 Identity = 350/350 (100.00%), Postives = 350/350 (100.00%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPSVSFNDLSNGKMKHFSTNSYLINNSKVLKATKNINVSSTSIDSGKDLKVVQCFQDCSKEDKSTNKSKDQQQDVTQKPGNDIPITKSEFLAFKKEVEQNIGKLSLRILTLIDEIDEEKKQRAASEIELVRIRRVVHMLDAQILNGFNH 1157
MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPSVSFNDLSNGKMKHFSTNSYLINNSKVLKATKNINVSSTSIDSGKDLKVVQCFQDCSKEDKSTNKSKDQQQDVTQKPGNDIPITKSEFLAFKKEVEQNIGKLSLRILTLIDEIDEEKKQRAASEIELVRIRRVVHMLDAQILNGFNH
Sbjct: 1 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPLSFKKKSSNDSDLSIKNVEKYSLNENSIPSPSVSFNDLSNGKMKHFSTNSYLINNSKVLKATKNINVSSTSIDSGKDLKVVQCFQDCSKEDKSTNKSKDQQQDVTQKPGNDIPITKSEFLAFKKEVEQNIGKLSLRILTLIDEIDEEKKQRAASEIELVRIRRVVHMLDAQILNGFNH 350
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Match: SMESG000001129.1 (SMESG000001129.1) HSP 1 Score: 218.779 bits (556), Expect = 1.190e-70 Identity = 106/111 (95.50%), Postives = 109/111 (98.20%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIV 440
MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLN +++
Sbjct: 1 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNGKILM 111
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Match: SMESG000079662.1 (SMESG000079662.1) HSP 1 Score: 132.109 bits (331), Expect = 1.255e-33 Identity = 85/205 (41.46%), Postives = 105/205 (51.22%), Query Frame = 3
Query: 108 MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNFVKVIKTDFKNTSNKENGTNPNVED-NLNTK----------------------------TKLKTHSSDQKTKTTKE--KSHI------NNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSE 611
MD + E+DY A ADEL++ KGDII SV E GW G L GKEGVFP NF K +K D + S ++N P E+ N NTK KLKT + D K K E K I + +V I SY AEN DE+T+E+GDII V NK D+GWW+G K G+ G+FP NFV+P E
Sbjct: 1 MDYLIEFDYDADEADELTIHKGDIINSVRPHEDGWMYGILRGKEGVFPSNFGKPVKED-RRKSQEDNLIIPQAEERNNNTKENDVVIEQTPPPKKVTGVGFGNIFSGGEIKLKTTNKDNKPKVISEEVKPEILQEKKPKETTRTKDVVRVIHSYTAENSDELTLEIGDIITVTNKEDEDEGWWRGRKSNGQSGVFPDNFVEPIKE 204
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Match: SMESG000074623.1 (SMESG000074623.1) HSP 1 Score: 79.337 bits (194), Expect = 1.274e-15 Identity = 51/194 (26.29%), Postives = 89/194 (45.88%), Query Frame = 3
Query: 114 CIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNG-----KEGVFPDNFVKVIKTDFKNT-------------------SNKENGTNPNVEDNLNTKTKLKTHSSDQKTK-TTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGS 620
C+A++ YS DEL+L +GD IK + GW +G L G FP N+V + + N S++ + + P+V ++T + H D K T K H SL V ++ + P+E++ + +I++VL++ + D WW+ G+IG+ P N+V+ + +GS
Sbjct: 273 CVAKFSYSPCQPDELALSRGDRIKVLEKSSDGWWRGELINNTSMLSAGWFPSNYVTLERPQHNNAFRSNTDSLGRQRTGPGMPVSSQLHSSMPSVTSGVDTTCLINNHHGDSAEKWTGPNKLH---SLQRFSTVLTLYPFSKNQPEEMSFDANEILEVLDRPIDDPDWWRCRNVNGDIGLVPRNYVKQLTSSGS 463 HSP 2 Score: 50.447 bits (119), Expect = 1.755e-6 Identity = 29/64 (45.31%), Postives = 36/64 (56.25%), Query Frame = 3
Query: 417 SLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKG--IKRTGEI--GIFPSNFV 596
SL + A FSY PDE+ + GD IKVL K+ DGWW+G I T + G FPSN+V
Sbjct: 266 SLGPVSVCVAKFSYSPCQPDELALSRGDRIKVLEKS--SDGWWRGELINNTSMLSAGWFPSNYV 327
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Match: SMESG000073128.1 (SMESG000073128.1) HSP 1 Score: 78.1814 bits (191), Expect = 2.676e-15 Identity = 56/169 (33.14%), Postives = 84/169 (49.70%), Query Frame = 3
Query: 120 AEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWL----NGKEGVFPDNFVKVIKTDFK----NTSN--KENGTNPNVEDNLNTKTKLKTHSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFV 596
A ++Y +DE+ + G+II + + GW W+ +GK G+FP N+V++I T+ + N N N NP+ EDN EKS L V A++SY A DEI+ E G+ + N N ID+GWW+G + G+ G+FPSN+V
Sbjct: 561 AVFEYECQDSDEIDFEVGEIITDIEEIDEGW---WIGCNKSGKRGMFPSNYVELIATNDEPIDINDENYSPANQQNPD-EDNA-------------------EKS---------LTVVAVYSYHALQDDEISFEEGE--HIYNVNQIDEGWWQGETKDGDKGMFPSNYV 695 HSP 2 Score: 66.6254 bits (161), Expect = 1.360e-11 Identity = 34/88 (38.64%), Postives = 52/88 (59.09%), Query Frame = 3
Query: 363 HSSDQKTKTTKEKSHINNSLNEPLIVEAIFSYKAENPDEITIEVGDIIKVLNKNLIDDGWWKGIKRTGEIGIFPSNFVQPFSENGSPL 626
H +Q TKT K KS +A+F Y+ ++ DEI EVG+II + + ID+GWW G ++G+ G+FPSN+V+ + N P+
Sbjct: 545 HLENQDTKTPKTKS-----------AKAVFEYECQDSDEIDFEVGEIITDIEE--IDEGWWIGCNKSGKRGMFPSNYVELIATNDEPI 619 The following BLAST results are available for this feature:
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 4
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of SH3 domain-containing kinase-binding protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025713 ID=SMED30025713|Name=SH3 domain-containing kinase-binding protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1261bpback to top protein sequence of SMED30025713-orf-1 >SMED30025713-orf-1 ID=SMED30025713-orf-1|Name=SMED30025713-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=351bp MDCIAEYDYSATHADELSLKKGDIIKSVIFFETGWKKGWLNGKEGVFPDNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
