Magnesium transporter NIPA2

Overview
NameMagnesium transporter NIPA2
Smed IDSMED30025679
Length (bp)1330
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Magnesium transporter NIPA2 (SMED30025679) t-SNE clustered cells

Violin plots show distribution of expression levels for Magnesium transporter NIPA2 (SMED30025679) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Magnesium transporter NIPA2 (SMED30025679) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Magnesium transporter NIPA2 (SMED30025679) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025679

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30025679SMESG000071002.1 dd_Smed_v4_8174_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30025679SMESG000071002.1 dd_Smed_v4_8174_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025679SMESG000071002.1 dd_Smed_v4_8174_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Match: NIPAL4 (NIPA like domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28018])

HSP 1 Score: 220.705 bits (561), Expect = 2.956e-66
Identity = 144/270 (53.33%), Postives = 197/270 (72.96%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             FYIGLGLA LS F++G S I+KK  L RL++ G  RA DGG+GYLKD MWW G L MAAGE+ N  AY FAPA++VTPLGALSVL++A LSS  L E LNLLGK+GC+IC+ GST++V+HAP+E+ V +I+E++ +   TGFI+F  L L+   IL+  + PRYG++N LIYI+I S IG+ SV +VKG+G+ +K   +G  V  + + Y++ + L L L  QVN+LN+ALD+FNT+++ P+ YV FT  V+ +S IL +EW  +S VD
Sbjct:  117 GFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVD 386
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Match: NIPA2 (NIPA magnesium transporter 2 [Source:HGNC Symbol;Acc:HGNC:17044])

HSP 1 Score: 206.453 bits (524), Expect = 5.621e-62
Identity = 136/270 (50.37%), Postives = 194/270 (71.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F  L +++  IL+  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE   G  V  + + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Match: NIPA2 (NIPA magnesium transporter 2 [Source:HGNC Symbol;Acc:HGNC:17044])

HSP 1 Score: 206.453 bits (524), Expect = 5.621e-62
Identity = 136/270 (50.37%), Postives = 194/270 (71.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F  L +++  IL+  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE   G  V  + + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Match: NIPA2 (NIPA magnesium transporter 2 [Source:HGNC Symbol;Acc:HGNC:17044])

HSP 1 Score: 206.453 bits (524), Expect = 5.621e-62
Identity = 136/270 (50.37%), Postives = 194/270 (71.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F  L +++  IL+  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE   G  V  + + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Match: NIPAL4 (NIPA like domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28018])

HSP 1 Score: 197.978 bits (502), Expect = 8.403e-58
Identity = 128/270 (47.41%), Postives = 180/270 (66.67%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             FYIGLGLA LS F++G S I+KK  L RL++ G  RA   G                   E+ N  AY FAPA++VTPLGALSVL++A LSS  L E LNLLGK+GC+IC+ GST++V+HAP+E+ V +I+E++ +   TGFI+F  L L+   IL+  + PRYG++N LIYI+I S IG+ SV +VKG+G+ +K   +G  V  + + Y++ + L L L  QVN+LN+ALD+FNT+++ P+ YV FT  V+ +S IL +EW  +S VD
Sbjct:  117 GFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVAAG-------------------EVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVD 367
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Celegans
Match: nipa-1 (NIPA1 (NonImprinted gene in Prader-Willi/Angelman syndrome region 1) homolog [Source:UniProtKB/TrEMBL;Acc:A3KFD2])

HSP 1 Score: 231.876 bits (590), Expect = 6.699e-72
Identity = 146/281 (51.96%), Postives = 205/281 (72.95%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLIS--RGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            T+ + H   T+FYIGLGLA+ S   +G S+I+KK +L +L S    +RA +GGYGYL++WMWW+G++ M  GE  N  AY FAPASLVTPLGALSV+VTA LSS++L+E LNLLG IGC +CL GST+IV+H+PKE+ V S+ +L+ +    GF+I+V L +L    +++++ PRYG  N L+YI + S IGSLSV+SVKG+G+ +KE + G   +T W+ Y  + S+ + + +Q+ YLNKALD+FNT+++TP+ YV FT FVI+ASSIL +EW  L   D
Sbjct:   26 TMDEVHYASTDFYIGLGLAVSSSLFIGSSFIIKKKALLKLASGDTSQRASEGGYGYLREWMWWMGVITMGIGEACNFAAYAFAPASLVTPLGALSVIVTAILSSRMLNERLNLLGSIGCALCLLGSTVIVIHSPKEEEVGSMADLALKMKDAGFLIYVILIILATGFIVVYVAPRYGHSNILVYISVCSLIGSLSVLSVKGLGLAIKETLAGNQQFTNWLTYFWLASVAMCVSVQLIYLNKALDIFNTSMVTPIYYVFFTTFVILASSILYKEWSCLGASD 306
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Celegans
Match: nipa-1 (NIPA1 (NonImprinted gene in Prader-Willi/Angelman syndrome region 1) homolog [Source:UniProtKB/TrEMBL;Acc:A3KFD2])

HSP 1 Score: 231.491 bits (589), Expect = 1.214e-71
Identity = 146/281 (51.96%), Postives = 205/281 (72.95%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLIS--RGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            T+ + H   T+FYIGLGLA+ S   +G S+I+KK +L +L S    +RA +GGYGYL++WMWW+G++ M  GE  N  AY FAPASLVTPLGALSV+VTA LSS++L+E LNLLG IGC +CL GST+IV+H+PKE+ V S+ +L+ +    GF+I+V L +L    +++++ PRYG  N L+YI + S IGSLSV+SVKG+G+ +KE + G   +T W+ Y  + S+ + + +Q+ YLNKALD+FNT+++TP+ YV FT FVI+ASSIL +EW  L   D
Sbjct:   45 TMDEVHYASTDFYIGLGLAVSSSLFIGSSFIIKKKALLKLASGDTSQRASEGGYGYLREWMWWMGVITMGIGEACNFAAYAFAPASLVTPLGALSVIVTAILSSRMLNERLNLLGSIGCALCLLGSTVIVIHSPKEEEVGSMADLALKMKDAGFLIYVILIILATGFIVVYVAPRYGHSNILVYISVCSLIGSLSVLSVKGLGLAIKETLAGNQQFTNWLTYFWLASVAMCVSVQLIYLNKALDIFNTSMVTPIYYVFFTTFVILASSILYKEWSCLGASD 325
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Fly
Match: spict (gene:FBgn0032451 transcript:FBtr0080397)

HSP 1 Score: 197.978 bits (502), Expect = 8.165e-59
Identity = 151/335 (45.07%), Postives = 227/335 (67.76%), Query Frame = 2 
Query:  155 EHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAI-KGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYK----DQSMLLLNNSNER 1141
            E  + T+FYIG+GLAI SCF +G S+I+KK +L RL   G+ RA  GG+GYL++W+WW GLL M  GE  N  AY FAPASLVTPLGALSV+++A ++S+ L+E LNLLGKIGC +C+ GSTIIV+H+PKE+ +  +  L +  +   FI++V   +     +  F+ PR+G  N ++YI + S IGSL+VMS K +G+ +++ +  G +V+  W+ + +I+  +  + IQ+NYLNKALD+FNT+I+TP+ YV FT  VI AS+IL +E+  + F D  G + GF+++I   FLL  F+D D++ N ++      M +    D+ +L+ +N+ ER
Sbjct:   38 ETVSNTDFYIGVGLAISSCFFIGSSFIIKKKALIRLSRYGEVRASAGGFGYLREWIWWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIISAVMASRFLNEKLNLLGKIGCFLCILGSTIIVIHSPKEKEIEDLQLLFDMLLDPVFILYVICIVGSTVFVACFIAPRHGHTNVVVYIFLCSGIGSLTVMSCKALGLAIRQTLNNGGNVFLTWMPWFLILVTVTFIAIQMNYLNKALDIFNTSIVTPVYYVMFTTLVIAASAILFKEFTHMRFDDILGDVCGFLIVITAVFLLNAFRDIDISLNDVRGLMRPKMQRVSQFDEEVLVTSNTKER 372
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Fly
Match: spict (gene:FBgn0032451 transcript:FBtr0329924)

HSP 1 Score: 197.978 bits (502), Expect = 1.112e-58
Identity = 151/335 (45.07%), Postives = 227/335 (67.76%), Query Frame = 2 
Query:  155 EHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAI-KGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYK----DQSMLLLNNSNER 1141
            E  + T+FYIG+GLAI SCF +G S+I+KK +L RL   G+ RA  GG+GYL++W+WW GLL M  GE  N  AY FAPASLVTPLGALSV+++A ++S+ L+E LNLLGKIGC +C+ GSTIIV+H+PKE+ +  +  L +  +   FI++V   +     +  F+ PR+G  N ++YI + S IGSL+VMS K +G+ +++ +  G +V+  W+ + +I+  +  + IQ+NYLNKALD+FNT+I+TP+ YV FT  VI AS+IL +E+  + F D  G + GF+++I   FLL  F+D D++ N ++      M +    D+ +L+ +N+ ER
Sbjct:   38 ETVSNTDFYIGVGLAISSCFFIGSSFIIKKKALIRLSRYGEVRASAGGFGYLREWIWWAGLLTMGVGEAANFAAYAFAPASLVTPLGALSVIISAVMASRFLNEKLNLLGKIGCFLCILGSTIIVIHSPKEKEIEDLQLLFDMLLDPVFILYVICIVGSTVFVACFIAPRHGHTNVVVYIFLCSGIGSLTVMSCKALGLAIRQTLNNGGNVFLTWMPWFLILVTVTFIAIQMNYLNKALDIFNTSIVTPVYYVMFTTLVIAASAILFKEFTHMRFDDILGDVCGFLIVITAVFLLNAFRDIDISLNDVRGLMRPKMQRVSQFDEEVLVTSNTKER 372
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Match: nipal4 (NIPA like domain containing 4 [Source:ZFIN;Acc:ZDB-GENE-040718-412])

HSP 1 Score: 202.216 bits (513), Expect = 4.760e-60
Identity = 143/313 (45.69%), Postives = 218/313 (69.65%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYKDQ 1108
            NF+ GL LA+LS F++G S I+KK +L RL + G+ RA +GG+GYLKDW+WW GLL M  GE  N  AY FAPA++VTPLGALSVL++A LSS +  E +NLLGK+GCM+ + GST++V+HAP+E+ V ++ E++E+ +  GF++F  + L+   IL+ ++ PR+G+ N L+YI I S +GS +V SVKG+G+ ++     T V    + ++++++LI  ++IQVNYLNK+LD FNT ++ P+ YV FT  V+  S IL +EW  +S VD  G I  F++I++G  +L  FKD +V +  L+S+    + ++ 
Sbjct:   68 NFWTGLTLAVLSAFLIGGSVILKKKALLRLANTGETRAAEGGHGYLKDWLWWGGLLTMGGGEAANFAAYMFAPATVVTPLGALSVLISAVLSSHLFRETMNLLGKLGCMLSVLGSTLMVIHAPEEEEVTTLKEMAEKLLDPGFLVFASILLVTCLILIFYVSPRFGQSNILVYISICSLLGSFTVSSVKGLGIAIRTMFTDTSVVRNPLMWILLLTLIGSIIIQVNYLNKSLDTFNTLLVYPIYYVFFTTVVLSTSVILFKEWGAMSGVDVVGTIGAFLVIVIGVSMLNIFKDLNVCFEDLRSNLCQPLSQES 380
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Match: zgc:101583 (zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75])

HSP 1 Score: 199.904 bits (507), Expect = 1.240e-59
Identity = 143/270 (52.96%), Postives = 197/270 (72.96%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N ++FYIGL LA+ S   +G S+I+KK  L RL S+G  RAG GGY YLK+W+WW GL+ M  GE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LN+ GKIGC++C+ GST++VLHAP+E+ V S+  ++E+    GFI F    ++   +L++F+ PRYG+KN L+YILI S IGSLSV  VKG+G+ +KE   GT V    +F+ ++I L++ + IQ++YLNKALD+FNT+I+TP+ YV FT  V+  S+IL +EW+++S
Sbjct:    5 NRSDFYIGLALAVSSTIFIGGSFILKKKGLLRLASKGSTRAGQGGYAYLKEWLWWAGLISMGIGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLSERLNIHGKIGCLLCIFGSTVMVLHAPQEEEVASLSAMAEKLKDPGFIAFAVCIVVSSLVLIIFVAPRYGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFGGTAVLKDPLFWALLICLVVCISIQISYLNKALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMS 274
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Match: zgc:101583 (zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75])

HSP 1 Score: 199.904 bits (507), Expect = 1.240e-59
Identity = 143/270 (52.96%), Postives = 197/270 (72.96%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N ++FYIGL LA+ S   +G S+I+KK  L RL S+G  RAG GGY YLK+W+WW GL+ M  GE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LN+ GKIGC++C+ GST++VLHAP+E+ V S+  ++E+    GFI F    ++   +L++F+ PRYG+KN L+YILI S IGSLSV  VKG+G+ +KE   GT V    +F+ ++I L++ + IQ++YLNKALD+FNT+I+TP+ YV FT  V+  S+IL +EW+++S
Sbjct:    5 NRSDFYIGLALAVSSTIFIGGSFILKKKGLLRLASKGSTRAGQGGYAYLKEWLWWAGLISMGIGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLSERLNIHGKIGCLLCIFGSTVMVLHAPQEEEVASLSAMAEKLKDPGFIAFAVCIVVSSLVLIIFVAPRYGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFGGTAVLKDPLFWALLICLVVCISIQISYLNKALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMS 274
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Match: zgc:101583 (zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75])

HSP 1 Score: 198.749 bits (504), Expect = 2.925e-59
Identity = 142/270 (52.59%), Postives = 197/270 (72.96%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N ++FYIGL LA+ S   +G S+I+KK  L RL ++G  RAG GGY YLK+W+WW GL+ M  GE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LN+ GKIGC++C+ GST++VLHAP+E+ V S+  ++E+    GFI F    ++   +L++F+ PRYG+KN L+YILI S IGSLSV  VKG+G+ +KE   GT V    +F+ ++I L++ + IQ++YLNKALD+FNT+I+TP+ YV FT  V+  S+IL +EW+++S
Sbjct:    5 NRSDFYIGLALAVSSTIFIGGSFILKKKGLLRLATKGSTRAGQGGYAYLKEWLWWAGLISMGIGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLSERLNIHGKIGCLLCIFGSTVMVLHAPQEEEVASLSAMAEKLKDPGFIAFAVCIVVSSLVLIIFVAPRYGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFGGTAVLKDPLFWALLICLVVCISIQISYLNKALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMS 274
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Match: nipa2 (NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2134])

HSP 1 Score: 182.185 bits (461), Expect = 7.156e-53
Identity = 162/350 (46.29%), Postives = 231/350 (66.00%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKL----KSDFFNNMYKDQSMLLLNNSNERTEINEITVNSGFVDIDEDVIPF 1207
            +FYIGL LAI S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LNL GK+GC++ + GST +V+HAP+E+ ++S+ +++++ +  GF++F    +++  I +  LGPR+G+ N L+YI I S IG+LSV  VKG+G+ +KEAI G  V    + +++++SLI  +  Q+NYLNKALD+FNT+++TP+ YV FT  V+  S+IL +EW  +   D  G + GF+ II+G FLL+ FKD  ++   L    + D  N    +  M   N+SN     NE+T +  F D  E  +PF
Sbjct:    9 DFYIGLALAISSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLTERLNLHGKLGCLLSILGSTTMVIHAPQEEEIDSLKDMAKKLVDPGFVVFATAVIIIALIFIFVLGPRHGQTNILVYITICSVIGALSVSCVKGLGIAIKEAIAGKPVLRNPLAWLLLLSLIACVSTQINYLNKALDIFNTSLVTPIYYVFFTTSVLSCSAILFKEWEHMGVDDIIGTLSGFVTIIVGIFLLHAFKDVSISLATLAVSIRKDERNGPVSN-GMAAHNHSNYELLRNEVTED--FED-REPGLPF 354
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Match: dcbld1 (discoidin, CUB and LCCL domain containing 1 [Source:Xenbase;Acc:XB-GENE-5944208])

HSP 1 Score: 194.512 bits (493), Expect = 1.697e-57
Identity = 135/270 (50.00%), Postives = 190/270 (70.37%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGL LAI S   +G S+I+KK  L RL   G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAP+E+ + S+ E+S +    GF++F    ++   IL+  +GPR+G+ N L+YI I S IG+LSV  VKG+G+ +K    G  V    + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  ++  D
Sbjct:    9 DFYIGLVLAISSSLFIGGSFILKKKGLLRLARSGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNEKLNLHGKIGCLLSILGSTVMVIHAPQEEEIGSLNEMSIKLADPGFLLFATGVVIASLILIFVVGPRHGQSNILVYISICSVIGALSVSCVKGLGIAIKGLFSGEPVLRNPLSWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQHMAVND 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Match: tomm40 (translocase of outer mitochondrial membrane 40 homolog [Source:Xenbase;Acc:XB-GENE-995150])

HSP 1 Score: 182.185 bits (461), Expect = 1.458e-51
Identity = 152/328 (46.34%), Postives = 219/328 (66.77%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFN---------NMYKDQSMLLLN 1126
            N YIGL LA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE  N  AY FAPA+LVTPLGALSVLV A LSS  L+E LN+ GK+GC++C+ GST++V+HAP+E+ V S+ ++  +  + GFI F  L +++  +L+ F+ P  G  N L+YI I S IG+ SV SVKG+G+ + + I+   V+   +FY++++ L++ +  Q+NYLNKALD+FNT+I+TP+ YV FT  V+  S IL +EW  +   D  G + GF+ II+G FLL+ FK++++TW+++ S             N  +DQ  LL N
Sbjct:  126 NLYIGLILAVSSSLFIGSSFIMKKKGLLRLAEKGSTRAGQGGFSYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLVCAVLSSHFLNEKLNMHGKLGCLLCILGSTMMVIHAPQEEEVTSLHDMEMKLRNPGFITFATLVVVVALLLIFFVAPSKGPSNILVYISICSVIGAFSVSSVKGLGIAIHDFIESKPVYKDPLFYILLVVLVVSVGTQINYLNKALDVFNTSIVTPIYYVFFTTMVVTCSVILFKEWNSMDASDMIGTLSGFLTIIIGIFLLHAFKNTNITWSQITSSVQKEKLSQANEANGQEDQHSLLGN 453
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Match: nipal4 (NIPA-like domain containing 4 [Source:NCBI gene;Acc:448461])

HSP 1 Score: 170.629 bits (431), Expect = 5.186e-48
Identity = 141/280 (50.36%), Postives = 194/280 (69.29%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRG-KRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            TVT  +    +F IGL LA+LS  ++G S I+KK  L RL   G  RAG GG+GYLKDWMWW GLL M  GE  N  AY FAPA++VTPLGALSVL++A LSS +L E LNLLGK+GC + + GST++V+HAP+EQ V ++ +++ +    GFI ++ L L+   +L+  L PRYG  N LIY+ I S +G+ SV SVKG+G+ +K  I G  V T+ + +++I  LIL ++ QVNYLNK+LD+FNT+++ P+ YV FT  VI  S IL +EW+ +S +D
Sbjct:   51 TVTQNY----DFLIGLLLAVLSSLLIGSSVILKKKGLLRLCRHGGTRAGAGGHGYLKDWMWWAGLLTMGGGEAANFAAYAFAPATIVTPLGALSVLISAVLSSYLLGERLNLLGKLGCTLSVLGSTVMVIHAPEEQAVTTLADMTLKLQDPGFIAYISLMLVCCLVLIFLLSPRYGHTNILIYLAICSLLGAFSVSSVKGLGIAVKGLIIGQPVITHPLPWILIPILILSVITQVNYLNKSLDVFNTSLVFPIYYVLFTSVVIATSLILFKEWVSMSALD 326
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Match: nipal4 (NIPA-like domain containing 4 [Source:NCBI gene;Acc:448461])

HSP 1 Score: 170.629 bits (431), Expect = 8.193e-48
Identity = 141/280 (50.36%), Postives = 194/280 (69.29%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRG-KRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            TVT  +    +F IGL LA+LS  ++G S I+KK  L RL   G  RAG GG+GYLKDWMWW GLL M  GE  N  AY FAPA++VTPLGALSVL++A LSS +L E LNLLGK+GC + + GST++V+HAP+EQ V ++ +++ +    GFI ++ L L+   +L+  L PRYG  N LIY+ I S +G+ SV SVKG+G+ +K  I G  V T+ + +++I  LIL ++ QVNYLNK+LD+FNT+++ P+ YV FT  VI  S IL +EW+ +S +D
Sbjct:   73 TVTQNY----DFLIGLLLAVLSSLLIGSSVILKKKGLLRLCRHGGTRAGAGGHGYLKDWMWWAGLLTMGGGEAANFAAYAFAPATIVTPLGALSVLISAVLSSYLLGERLNLLGKLGCTLSVLGSTVMVIHAPEEQAVTTLADMTLKLQDPGFIAYISLMLVCCLVLIFLLSPRYGHTNILIYLAICSLLGAFSVSSVKGLGIAVKGLIIGQPVITHPLPWILIPILILSVITQVNYLNKSLDVFNTSLVFPIYYVLFTSVVIATSLILFKEWVSMSALD 348
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Match: MGC108429 (MGC108429 protein [Source:NCBI gene;Acc:595009])

HSP 1 Score: 155.992 bits (393), Expect = 4.129e-43
Identity = 127/270 (47.04%), Postives = 182/270 (67.41%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N  +FYIGL LA+ S   +G S+I+KK  L +L SRG+ RAG GG+ YLK+W+WW GLL M  GE  N  AY FAPA+LVTPLG LSVLV+A LSS  L+E+L    K GC + + GSTI+VLHAP+E+ V+++ ++  +    GF+ FV   LL  F+L L   PR+G    L+Y+LI S +GSLSV  VKG+G+ ++    G  V+   + +V+++ L + + +Q++YLN+ALD+F  +++TP+ YV FT  V+  S+IL +EW  LS
Sbjct:    6 NRYDFYIGLALALSSSIFIGSSFILKKKGLLKLCSRGQLRAGHGGHAYLKEWLWWAGLLSMGLGEAANFAAYIFAPATLVTPLGGLSVLVSAVLSSYFLNEYLTSPAKTGCALSILGSTIMVLHAPQEEEVSTLSDMEVKLKQPGFLAFVSCVLLFSFLLALLAAPRWGHSYVLVYVLICSLVGSLSVACVKGLGIAIRGLFSGLPVFKDPLGWVLLLCLCICISVQIHYLNRALDVFTASLVTPIYYVLFTSSVLACSAILFQEWQHLS 275
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Match: Nipal4 (NIPA-like domain containing 4 [Source:MGI Symbol;Acc:MGI:2444671])

HSP 1 Score: 222.631 bits (566), Expect = 7.279e-68
Identity = 140/270 (51.85%), Postives = 198/270 (73.33%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             FYIG+GLA LSCF++G S I+KK  L RL++ G  RA +GGYGYLKD MWW G+  M+AGE+ N  AY FAPA++VTPLGALSVL++A  SS  L E LNLLGK+GC+IC+ GST++V+HAPKE+ V ++ E++ +   TGFI+F  L ++   IL+  + PRYG++N LIYI+I S IGS SV +VKG+GV ++   +G  V  + + Y++ + L L ++IQVN+LN+ALD+FNT+++ P+ YV FT  V+ +S +L +EW  +S VD
Sbjct:   57 GFYIGVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVANFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPKEEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRNFFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYVFFTTVVVASSIVLFKEWYTMSAVD 326
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Match: Nipa2 (non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) [Source:MGI Symbol;Acc:MGI:1913918])

HSP 1 Score: 207.223 bits (526), Expect = 1.902e-62
Identity = 133/270 (49.26%), Postives = 192/270 (71.11%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F    +++  I +  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE + G  V  + + ++++ SL++ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Match: Nipa2 (non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) [Source:MGI Symbol;Acc:MGI:1913918])

HSP 1 Score: 207.223 bits (526), Expect = 1.902e-62
Identity = 133/270 (49.26%), Postives = 192/270 (71.11%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F    +++  I +  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE + G  V  + + ++++ SL++ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Match: Nipa2 (non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) [Source:MGI Symbol;Acc:MGI:1913918])

HSP 1 Score: 207.223 bits (526), Expect = 1.902e-62
Identity = 133/270 (49.26%), Postives = 192/270 (71.11%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F    +++  I +  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE + G  V  + + ++++ SL++ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Match: Nipa2 (non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) [Source:MGI Symbol;Acc:MGI:1913918])

HSP 1 Score: 207.223 bits (526), Expect = 1.902e-62
Identity = 133/270 (49.26%), Postives = 192/270 (71.11%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F    +++  I +  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE + G  V  + + ++++ SL++ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Match: sp|Q8BZF2|NIPA4_MOUSE (Magnesium transporter NIPA4 OS=Mus musculus OX=10090 GN=Nipal4 PE=1 SV=1)

HSP 1 Score: 222.631 bits (566), Expect = 5.092e-67
Identity = 140/270 (51.85%), Postives = 198/270 (73.33%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             FYIG+GLA LSCF++G S I+KK  L RL++ G  RA +GGYGYLKD MWW G+  M+AGE+ N  AY FAPA++VTPLGALSVL++A  SS  L E LNLLGK+GC+IC+ GST++V+HAPKE+ V ++ E++ +   TGFI+F  L ++   IL+  + PRYG++N LIYI+I S IGS SV +VKG+GV ++   +G  V  + + Y++ + L L ++IQVN+LN+ALD+FNT+++ P+ YV FT  V+ +S +L +EW  +S VD
Sbjct:   57 GFYIGVGLAFLSCFLIGTSVILKKKGLIRLVATGATRAVNGGYGYLKDPMWWAGMATMSAGEVANFGAYAFAPATVVTPLGALSVLISAIFSSYCLGESLNLLGKLGCVICMAGSTVMVIHAPKEEKVTTVAEMASKMKDTGFIVFAVLLVVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRNFFQGLPVVRHPLPYILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYVFFTTVVVASSIVLFKEWYTMSAVD 326
[Close]
BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Match: sp|Q0D2K0|NIPA4_HUMAN (Magnesium transporter NIPA4 OS=Homo sapiens OX=9606 GN=NIPAL4 PE=1 SV=3)

HSP 1 Score: 220.705 bits (561), Expect = 1.420e-65
Identity = 144/270 (53.33%), Postives = 197/270 (72.96%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             FYIGLGLA LS F++G S I+KK  L RL++ G  RA DGG+GYLKD MWW G L MAAGE+ N  AY FAPA++VTPLGALSVL++A LSS  L E LNLLGK+GC+IC+ GST++V+HAP+E+ V +I+E++ +   TGFI+F  L L+   IL+  + PRYG++N LIYI+I S IG+ SV +VKG+G+ +K   +G  V  + + Y++ + L L L  QVN+LN+ALD+FNT+++ P+ YV FT  V+ +S IL +EW  +S VD
Sbjct:  117 GFYIGLGLAFLSSFLIGSSVILKKKGLLRLVATGATRAVDGGFGYLKDAMWWAGFLTMAAGEVANFGAYAFAPATVVTPLGALSVLISAILSSYFLRESLNLLGKLGCVICVAGSTVMVIHAPEEEKVTTIMEMASKMKDTGFIVFAVLLLVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLPYILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVD 386
[Close]
BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Match: sp|Q9JJC8|NIPA2_MOUSE (Magnesium transporter NIPA2 OS=Mus musculus OX=10090 GN=Nipa2 PE=1 SV=1)

HSP 1 Score: 207.223 bits (526), Expect = 1.331e-61
Identity = 133/270 (49.26%), Postives = 192/270 (71.11%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F    +++  I +  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE + G  V  + + ++++ SL++ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLAWILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Match: sp|Q5R7Q3|NIPA2_PONAB (Magnesium transporter NIPA2 OS=Pongo abelii OX=9601 GN=NIPA2 PE=2 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 2.700e-61
Identity = 136/270 (50.37%), Postives = 194/270 (71.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F  L +++  IL+  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE   G  V  + + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Match: sp|Q8N8Q9|NIPA2_HUMAN (Magnesium transporter NIPA2 OS=Homo sapiens OX=9606 GN=NIPA2 PE=2 SV=1)

HSP 1 Score: 206.453 bits (524), Expect = 2.700e-61
Identity = 136/270 (50.37%), Postives = 194/270 (71.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +FYIGLGLA+ S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GKIGC++ + GST++V+HAPKE+ + ++ E+S +    GF++F  L +++  IL+  +GPR+G+ N L+YI I S IG+ SV  VKG+G+ +KE   G  V  + + +++++SLI+ +  Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW  +   D
Sbjct:    9 DFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
[Close]
BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Match: A0A0X3NX63 (Magnesium transporter NIPA2 OS=Schistocephalus solidus OX=70667 GN=NIPA2 PE=4 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 2.087e-72
Identity = 148/272 (54.41%), Postives = 200/272 (73.53%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKG--THVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDY 982
            NFYIGL LA+LS   +G S+IVKK++L RL + G RAGDGG  YL DW+WW GL+LM  GE  N   Y FAPASLVTP+G LSVLV+A LSS  L E LN  GKIGC++CLCGST++VLHAPKEQ V ++ EL E+ +  GF+I+    ++   I +  + PR+G++NPL+++ IS SIGSLSVM+ KGIG+ +KEA++     V T WIF+  ++ L   L +Q+NYLN+ALD+FNT+++TPL+YV FT FV++AS+IL +E   L+ +DY
Sbjct:   10 NFYIGLSLALLSTLFIGCSFIVKKIALRRLAANGTRAGDGGLQYLCDWVWWFGLILMGIGEGANFAGYAFAPASLVTPMGGLSVLVSAVLSSHFLGEDLNFPGKIGCIVCLCGSTMVVLHAPKEQEVQTLRELGEKVLDPGFLIYASFIIVAAIISIFLIAPRFGQRNPLVFVFISGSIGSLSVMACKGIGLGIKEAVENGILTVCTQWIFWFFLLGLAFCLSVQLNYLNRALDIFNTSVVTPLLYVFFTAFVLIASAILFKEGSTLTVLDY 281
[Close]
BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Match: A0A3P6I4V2 (Uncharacterized protein OS=Mesocestoides corti OX=53468 GN=MCOS_LOCUS8932 PE=4 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 4.214e-72
Identity = 166/318 (52.20%), Postives = 222/318 (69.81%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIK--GTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFN 1090
            TV +   + ++FYIGL LA+ S   +G S+IVKK++L RL + G RAGDGGY YL DW+WWLGL+LM  GE+ N   Y FAPASLVTP+G LSVLV+A LSS  L E LN  GKIGC++CLCGST++VLHAPKEQ V S+ ELS + +  GF+ +     +   + +  + P++G +NPL+++ IS SIGSLSVM+ KGIG+ +KEAI+     +   WIF+  ++ L   L +Q+NYLN+ALD+FNT+I+TPL+YV FT FV++AS+IL +E   LS  DY G  VG I I+ G  LL  FKD +V+ N L  DF N
Sbjct:   21 TVENMTQSDSHFYIGLALAVSSTVFIGCSFIVKKVALRRLAATGTRAGDGGYQYLCDWVWWLGLILMGLGEVANFAGYAFAPASLVTPMGGLSVLVSAVLSSHFLGERLNFTGKIGCVVCLCGSTMVVLHAPKEQEVQSLHELSTKVLDPGFLTYAIAITIAGIVSIFVVAPKFGSRNPLVFVFISGSIGSLSVMACKGIGLGIKEAIEYGVLALLQQWIFWFFLVGLTFCLTVQLNYLNRALDVFNTSIVTPLLYVFFTAFVLIASTILFKEGSSLSPTDYIGNAVGLICIVSGIVLLTLFKDLNVSLNDLVKDFAN 338
[Close]
BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Match: A0A5K3FBX1 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 4.516e-72
Identity = 167/318 (52.52%), Postives = 220/318 (69.18%), Query Frame = 2 
Query:  143 TVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIK--GTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFN 1090
            T +D H     FYIGL LA+ S   +G S+IVKK++L RL + G RAGDGGY YL DW+WWLGL+LM  GE+ N   Y FAPASLVTP+G LSVLV+A LSS  L E LN  GKIGC++CLCGST++VLHAPKEQ V S+ ELS + +  GF+ +     +   + +  + P++G +NPL+++ IS SIGSLSVM+ KGIG+ +KEAI+     +   WIF+  ++ L   L +Q+NYLN+ALD+FNT+I+TPL+YV FT FV++AS+IL +E   LS  DY G  VG I I+ G  LL  FKD +V+ N L  DF N
Sbjct:    2 TQSDSH-----FYIGLALAVSSTVFIGCSFIVKKVALRRLAATGTRAGDGGYQYLCDWVWWLGLILMGLGEVANFAGYAFAPASLVTPMGGLSVLVSAVLSSHFLGERLNFTGKIGCVVCLCGSTMVVLHAPKEQEVQSLHELSTKVLDPGFLTYAIAITIAGIVSIFVVAPKFGSRNPLVFVFISGSIGSLSVMACKGIGLGIKEAIEYGVLALLQQWIFWFFLVGLTFCLTVQLNYLNRALDVFNTSIVTPLLYVFFTAFVLIASTILFKEGSSLSPTDYIGNAVGLICIVSGIVLLTLFKDLNVSLNDLVKDFAN 314
[Close]
BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Match: A0A0X3NX99 (Magnesium transporter NIPA2 OS=Schistocephalus solidus OX=70667 GN=NIPA2 PE=4 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 9.825e-72
Identity = 148/272 (54.41%), Postives = 200/272 (73.53%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGT--HVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDY 982
            NFYIGL LA+LS   +G S+IVKK++L RL + G RAGDGG  YL DW+WW GL+LM  GE  N   Y FAPASLVTP+G LSVLV+A LSS  L E LN  GKIGC++CLCGST++VLHAPKEQ V ++ EL E+ +  GF+I+    ++   I +  + PR+G++NPL+++ IS SIGSLSVM+ KGIG+ +KEA++     V T WIF+  ++ L   L +Q+NYLN+ALD+FNT+++TPL+YV FT FV++AS+IL +E   L+ +DY
Sbjct:   10 NFYIGLSLALLSTLFIGCSFIVKKIALRRLAANGTRAGDGGLQYLCDWVWWFGLILMGIGEGANFAGYAFAPASLVTPMGGLSVLVSAVLSSHFLGEDLNFPGKIGCIVCLCGSTMVVLHAPKEQEVQTLRELGEKVLDPGFLIYASFIIVAAIISIFLIAPRFGQRNPLVFVFISGSIGSLSVMACKGIGLGIKEAVENGILTVCTQWIFWFFLLGLAFCLSVQLNYLNRALDIFNTSVVTPLLYVFFTAFVLIASAILFKEGSTLTVLDY 281
[Close]
BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Match: A0A267EJX4 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009478g1 PE=4 SV=1)

HSP 1 Score: 240.35 bits (612), Expect = 2.154e-71
Identity = 151/283 (53.36%), Postives = 204/283 (72.08%), Query Frame = 2 
Query:  131 TSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            T+   V+       +FYIGL LA+ S   +G S+I+KK +L RL +RG RAG+GGYGYL+D +WW G L+MAAGE  N  AY FAPASLVTPLGALSVLV+A L+SK L+E LNLLGKIGC++CL GST+IV+HAPKEQ V ++ EL  +    GFI +V + L    +L+ +  PRYG+ NPL+YI IS S+GSLSVM  KG GV +K+   G +V+   + +++I S+   + +Q+NYLNKALD+FNT++++P++YV FT FVI+ASSIL +EW  +   D
Sbjct:   17 TNASMVSSASNGRFDFYIGLFLAMSSSLFIGTSFILKKKALIRLSNRGIRAGEGGYGYLRDVVWWSGFLMMAAGEGANFAAYAFAPASLVTPLGALSVLVSAMLASKFLNERLNLLGKIGCLVCLLGSTMIVIHAPKEQEVTTMQELVLKLKDFGFISYVAIVLAASAVLIFYFAPRYGRTNPLVYITISGSLGSLSVMGCKGTGVAIKQTFAGDNVFVLPVTWLLIASVSFFVTVQMNYLNKALDIFNTSVVSPILYVFFTTFVIIASSILYKEWFNMKPED 299
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Match: nipal4 (magnesium transporter NIPA2-like [Source:NCBI gene;Acc:103031803])

HSP 1 Score: 204.912 bits (520), Expect = 3.588e-61
Identity = 148/314 (47.13%), Postives = 222/314 (70.70%), Query Frame = 2 
Query:  170 TNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYKDQ 1108
            +NF+IGL LA+LS F++G S I+KK +L RL + G  RAG+GG+GYLKDW+WW GLL M  GE  N  AY FAPA++VTPLGALSVL +A LSS +  E +NLLGK+GCM+ L GSTI+V+HAP+E+ V ++ E+S + +  GF++F  + L+   +L+ +  PR+G+ N LIYI I S +G+ +V SVKG+G+ ++ AI    V+ + + ++++++L+  ++IQ+NYLNK+LD FNT ++ P+ YV FT  V+  S IL +EW  +S VD  G + GF++I+LG  +L+ FKD +V+   L+    NN+ + Q
Sbjct:   62 SNFWIGLSLAVLSAFLIGGSVILKKKALLRLATNGHTRAGEGGHGYLKDWLWWGGLLTMGGGEAANFAAYMFAPATVVTPLGALSVLFSAVLSSHLFGETMNLLGKLGCMLSLLGSTIMVIHAPEEEAVTTLKEMSSKLLDPGFLVFASILLVTCLVLIFYCSPRFGQTNILIYISICSLLGAFTVSSVKGLGIAIRTAISDPLVFRHPLTWILLLTLVSSIIIQINYLNKSLDTFNTLLVYPIYYVFFTTVVLTTSIILFKEWETMSGVDVVGTVGGFLVIVLGVSMLHIFKDLEVSLQGLR----NNLCQPQ 371
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Match: nipa2 (NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2134])

HSP 1 Score: 181.8 bits (460), Expect = 3.569e-53
Identity = 132/263 (50.19%), Postives = 190/263 (72.24%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEW 958
            +FYIGL LAI S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LNL GK+GC++ + GST +V+HAP+E+ ++S+ +++++ +  GF++F    +++  I +  +GPR+G+ N L+YI I S IG+LSV  VKG+G+ +KEAI G  V    + +++++SL+  +  Q+NYLNKALD+FNT+++TP+ YV FT  V+  S+IL +EW
Sbjct:    9 DFYIGLALAISSSIFIGGSFILKKKGLLRLARKGSTRAGQGGHAYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLTERLNLHGKLGCLLSILGSTTMVIHAPQEEEIDSLKDMAKKLVDPGFVVFATFVIIIALIFIFVVGPRHGQTNILVYITICSVIGALSVSCVKGLGIAIKEAIAGQPVLRNPLAWLLLLSLVACVSTQINYLNKALDIFNTSLVTPIYYVFFTTSVLTCSAILFKEW 271
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Match: nipa1 (NIPA magnesium transporter 1 [Source:NCBI gene;Acc:103040322])

HSP 1 Score: 147.902 bits (372), Expect = 1.385e-40
Identity = 112/270 (41.48%), Postives = 175/270 (64.81%), Query Frame = 2 
Query:  182 IGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWT----YWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +G+G+AI+S F+ G +++++K    + I R +R+G     YL D +WW G L M  G+I N +A+  APA LVTPLGAL VL  A L+S +L EHLN+LGK+GC++C CGS ++++H+PK + V S VE  ER +   F+ +  L +L++ IL+ +L P YGK N ++Y+ I S +G  +V S KG+G+  K+A  G    T     ++F  ++  L++ +LIQ  ++NKAL+ F++N+   + YV FT  VI+AS+IL +EW  L  +D
Sbjct:    9 VGVGIAIVSSFINGSTFVLQK----KGILRARRSGRS---YLSDCVWWCGTLAMIVGQIGNFLAHNAAPAVLVTPLGALGVLFGAILASLLLQEHLNMLGKLGCVLCCCGSFVLIIHSPKSEGVASSVEFEERLLDPVFLSYTALVVLLLIILIGWLSPAYGKSNIMVYVGICSLLGCFTVPSCKGLGLAAKDAFGGDAFTTDNRALYLFLCLLAVLLVSILIQFTFINKALENFSSNMFEAVYYVVFTSSVILASAILFKEWEALGILD 271
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Match: zgc:101583 (zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75])

HSP 1 Score: 80.8777 bits (198), Expect = 1.964e-17
Identity = 72/152 (47.37%), Postives = 104/152 (68.42%), Query Frame = 2 
Query:  656 PRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYKDQS 1111
            PRYG+KN L+YILI S IGSLSV  VKG+G+ +KE   G  V    +F+ ++I L++ + IQ++YLNKALD+FNT+I+TP+ YV FT  V+  S+IL +EW+++S     G + GF+ IILG FLL+ FKD+  +W+ L  ++      D S
Sbjct:   12 PRYGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFSGQAVLKDPLFWALLICLVICVSIQISYLNKALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMSTDGVVGTVSGFLTIILGIFLLHAFKDATFSWDSLP-EYLRGALSDSS 162
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Match: NIPAL2 (NIPA like domain containing 2 [Source:NCBI gene;Acc:103038905])

HSP 1 Score: 74.3294 bits (181), Expect = 3.459e-14
Identity = 69/211 (32.70%), Postives = 120/211 (56.87%), Query Frame = 2 
Query:  353 EIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKE--QIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVW-TYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFV 976
            E+ N  AYGFAPASL+ PLG +SV+ +A +S   L E L     +G  + L G+ ++V  AP     +  ++VE     IS  F+ +  + +++  ILL     R    + +I +L+ + + S++V+SVK +   L E I+G+H+  TY +FYV+ + +++    Q+ +LN+A+ +F+   I P+ YV FT   ++A  +  EE+  LS +
Sbjct:   57 ELGNFAAYGFAPASLIAPLGCVSVIASAVISVVFLKETLRASDLLGGALALTGTYLLVTFAPHSAPHVTANMVE--RCLISWQFLAYFFIEVVLFCILLFLYKCR-NVNHIVIVMLLVALLASVTVISVKAVSGMLTETIRGSHLQLTYPVFYVMFVVMVISCAFQIKFLNEAMKMFDATEIVPINYVFFTASAVIAGILFYEEFYGLSII 264
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Sea Lamprey
Match: nipa2 (NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2134])

HSP 1 Score: 209.149 bits (531), Expect = 5.690e-64
Identity = 162/328 (49.39%), Postives = 225/328 (68.60%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYKDQSMLLLNNSNERTEIN 1153
             FY+GLGLAI S   +G SYI+KK  L +L   G  RAG GG+ YLK+W+WW GLL M AGE  N  AY FAPA+LVTPLGALSVLV+A LSS  L+E LNL GK+GCM+CL GST++V+HAP+E+ V S+  ++ +    GFI+F  + ++   +L+  + PRYG+ N L+YI I S IG+LSV SVKG+G+ +KEAI G  ++   + +++++SL+  +  Q+NYLNKALD+FNT+I+TP+ YV FT  V+V S+IL +EW  +S  D  G I GF+ IILG FLL+ FKD ++T   L + F     +  SM     S+ ++ +N
Sbjct:   10 GFYVGLGLAISSSLFIGGSYILKKKGLLKLAKTGSTRAGQGGHAYLKEWLWWAGLLSMGAGEGANFAAYAFAPATLVTPLGALSVLVSAVLSSYYLNEKLNLHGKLGCMLCLLGSTVMVIHAPQEEEVESLEVMAVKLQDPGFIVFATVVVISSLVLVFAVAPRYGQTNVLVYISICSVIGALSVSSVKGLGIAIKEAIGGRPMFKEPLTWILLMSLVACVATQINYLNKALDIFNTSIVTPIYYVFFTTSVMVCSAILFKEWYHMSAADIIGTISGFLTIILGIFLLHAFKDINLTLGSLPT-FMRRFDRAPSMTNGGTSDRQSLLN 336
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Sea Lamprey
Match: zgc:101583 (zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75])

HSP 1 Score: 164.851 bits (416), Expect = 2.049e-47
Identity = 127/272 (46.69%), Postives = 190/272 (69.85%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRG-KRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKG--THVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            NFYIGL LA+ S   +G S+I+KK  L +L ++G  RAG+G + YLK+W+WW GL+ MA GE  N  AY FAPA+LVTPLGALSV++++ LSS  L E LNLLGK+GC +CL GSTI+V+HAP+ Q V+S+ E++ R    GF+ F  + +    +L++   PR+G  N L+Y+ I S +G+L+V  VKG+G+ ++E + G    V T  + YV++  ++  L++Q+NYLN++LD+F+T ++TP+ YVCFT  V++ S++L  EW  +S  D
Sbjct:   33 NFYIGLALAVASSIFIGGSFILKKRGLLQLQAKGVSRAGEGSHAYLKEWIWWAGLISMALGEGANFAAYAFAPAALVTPLGALSVIISSTLSSCFLGERLNLLGKVGCALCLLGSTIMVIHAPEAQEVSSLYEMARRVQEPGFVAFAVVAVAASLVLVVVFVPRWGDSNVLVYVGICSVVGALTVACVKGLGIAVRELVAGRWRTVLTDPLAYVLLFGMVGCLVVQLNYLNRSLDVFSTALVTPVYYVCFTSAVLLCSAVLF-EWEGMSGHD 303
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010214.1 (pep scaffold:Pmarinus_7.0:GL484904:7619:12052:-1 gene:ENSPMAG00000009245.1 transcript:ENSPMAT00000010214.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.872 bits (320), Expect = 4.806e-34
Identity = 87/196 (44.39%), Postives = 131/196 (66.84%), Query Frame = 2 
Query:  392 SLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            SLVTPLGALS+LVTA L+  +L E L  LG++GC++ + G+ ++V+HAP++  V S+ E+        FI +  L + +   L +   PR+G  N L+Y+LI S++GSLSV SVKG+ + LKE   G  V+T  + + ++ISLI  +  Q+NYLNKALD F+T+++TP+ YV FT  V++ S+IL +EW  +  VD
Sbjct:   21 SLVTPLGALSILVTAVLAWCVLGERLEHLGRLGCLLSVLGAVVMVVHAPQDVEVASLNEMLIHLQDPAFITYAVLVVCVAVALAVIAVPRFGNSNVLVYVLICSTVGSLSVASVKGLSLVLKELFMGKSVFTQPLTWGLLISLIACITTQINYLNKALDTFSTHVVTPVYYVAFTSCVVICSAILFQEWRGVGAVD 216
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Sea Lamprey
Match: nipa1 (NIPA magnesium transporter 1 [Source:ZFIN;Acc:ZDB-GENE-041010-164])

HSP 1 Score: 90.1225 bits (222), Expect = 9.627e-21
Identity = 74/203 (36.45%), Postives = 106/203 (52.22%), Query Frame = 2 
Query:  362 NSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKE----AIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEW 958
            N VAY  APA+LVTPLGA  +   A L+S +L E L+ LGK+GC++C  G   I++H PK   V  + EL +R     F  +V L LL++  L+L      G  + L+ I I S  GS +V S KG+G+ + E    A   +      +       L + L  Q+ YL  AL   ++  + P+ Y  FT+ V  ASS+L  EW
Sbjct:   24 NFVAYNLAPATLVTPLGAFGIPFGAVLASWLLGERLSPLGKLGCVLCCVGCIEIIIHTPKASEVQRLAELEDRLTDPVFWAYVALVLLVLLTLVLRAASPAGSSDALVPIAICSLFGSFTVPSAKGLGLAVSELLPSAAPPSTPHAPQLALAAAAVLTVSLPAQLRYLTCALAASSSATVVPVYYAGFTVSVTAASSVLFREW 226
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Nematostella
Match: EDO31653 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXC3])

HSP 1 Score: 210.305 bits (534), Expect = 5.759e-64
Identity = 134/263 (50.95%), Postives = 187/263 (71.10%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISR-GKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEW 958
            +FY GLGLAI S   +G S+IVKK  L R+  R G RAG GGY YLK+W+WW+G++ M  GEI N  AY FAPA LVTPLGALSVLV+A L+S  L E  NL GK+GC++ + GST++V+HAP+E+ V++I +L  + I  GFII+  + +L+ F+L+    P+YGK N L+YI I S IGSLSVM  KG+G+ LK+ +KG       + + ++ +++     Q+NYLNKALD+FNT+++TP+ YV FT+  I+AS+IL +EW
Sbjct:   31 DFYTGLGLAISSSVFIGSSFIVKKKGLLRVAQRSGVRAGQGGYAYLKEWLWWIGMISMIFGEIANFSAYAFAPAILVTPLGALSVLVSAVLASYFLDEKQNLHGKVGCILSIIGSTVLVIHAPQEEAVDTIEQLESKLIEPGFIIYAVMVVLLAFVLIWRYAPKYGKTNILVYIAICSLIGSLSVMGCKGVGIVLKQTLKGDSQVGNPVSWALLFTVLTCATTQINYLNKALDIFNTSLVTPIYYVMFTLLTIIASAILFKEW 293
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Nematostella
Match: EDO30141 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1M4])

HSP 1 Score: 69.3218 bits (168), Expect = 3.405e-13
Identity = 59/209 (28.23%), Postives = 118/209 (56.46%), Query Frame = 2 
Query:  353 EIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            E+ N  AYGFAPASLV PLG  +V+  A ++   L E +      G ++ + G+ +++  + K+    +  EL+       F +F  +  ++ F +LL++  RY  +N ++++L+ + +GSL+V+S K +   +   + G +   Y + Y+++I ++   + QV +LN+A+  F+  ++ P  +V FTI  I++  +L  E+  L+F++
Sbjct:   54 EVGNFSAYGFAPASLVAPLGTTTVIANAVIAVVFLKEKIRYQDVFGVLLAIVGAFLLITFSTKDYAELTGQELAFYMKQWPF-LFYLVIEIVTFCVLLYVQMRYNLENVVVFLLLVALLGSLTVISAKAVSSMINITLGGDNQLGYPLLYIMLIVMVTTAIAQVKFLNRAMKSFDATVVVPTNFVLFTISAIISGIVLYREFYGLTFLE 261
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Nematostella
Match: EDO45127 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTQ2])

HSP 1 Score: 68.9366 bits (167), Expect = 3.736e-13
Identity = 59/209 (28.23%), Postives = 118/209 (56.46%), Query Frame = 2 
Query:  353 EIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            E+ N  AYGFAPASLV PLG  +V+  A ++   L E +      G ++ + G+ +++  + K+    +  EL+       F +F  +  ++ F +LL++  RY  +N ++++L+ + +GSL+V+S K +   +   + G +   Y + Y+++I ++   + QV +LN+A+  F+  ++ P  +V FTI  I++  +L  E+  L+F++
Sbjct:   54 EVGNFSAYGFAPASLVAPLGTTTVIANAVIAVVFLKEKIRYQDVFGVLLAIVGAFLLITFSTKDYAELTGQELAFYMKQWPF-LFYLVIEIVAFCVLLYVQMRYNLENVVVFLLLVALLGSLTVISAKAVSSMINITLGGDNQLGYPLLYIMLIVMVTTAIAQVKFLNRAMKSFDATVVVPTNFVLFTISAIISGIVLYREFYGLTFLE 261
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Match: nipal4 (magnesium transporter NIPA2 [Source:NCBI gene;Acc:101159483])

HSP 1 Score: 201.445 bits (511), Expect = 1.002e-59
Identity = 134/286 (46.85%), Postives = 201/286 (70.28%), Query Frame = 2 
Query:  125 VNTSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            +N S  T   +   + N ++GL LA+LS F++G S I+KK +L RL   G+ RAG+GG+GYLKDW+WW GLL M AGE+ N  AY FAPA+LVTPLGALSVL++A LSS +L E LN++GK+GC +C+ GS ++VLHAP+EQ V S+ +++ + +  GF+++ GL L++  +L+L+  PR G+ N L+YI I S +G+ +V SVKG+ + +   +K   V +  + ++++ +LI  ++ QVNYLNK+LD FNT ++ P+ YV FT  V+  S IL +EW ++S VD
Sbjct:   40 LNGSLQTTGQQTYTVYNMWLGLVLALLSAFLIGGSVILKKKALLRLARNGQTRAGEGGHGYLKDWLWWGGLLTMGAGELCNFAAYMFAPATLVTPLGALSVLISAVLSSYVLGEMLNIVGKLGCFLCVLGSVLLVLHAPQEQEVTSLQDMTNKLLKPGFLVYAGLVLVLCAVLILYFCPRSGRSNILVYISICSLLGAFTVSSVKGLAIAINTVLKDLSVLSNPLTWILLFTLITSIVTQVNYLNKSLDTFNTLLVYPIYYVLFTSVVLSTSIILFQEWSRMSIVD 325
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Match: zgc:101583 (magnesium transporter NIPA2 [Source:NCBI gene;Acc:101155856])

HSP 1 Score: 197.978 bits (502), Expect = 5.455e-59
Identity = 136/270 (50.37%), Postives = 195/270 (72.22%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N  NFYIGL LA+ S   +G S+I+KK  L RL S+G  RAG GG+ YLK+W+WW GL+ M  GE  N  AY FAPA+LVTPLGALSVLV+A LS+  L+E LN+ GK+GC++C+ GST++V+HAP+E+ V S+  ++E+    GFI+F    +    +L+  + PR+G+KN L+YILI S IGSLSV  VKG+G+ +KE   GT V    +F+ ++I L++ + +Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW++++
Sbjct:    4 NRVNFYIGLSLAVSSSAFIGASFILKKKGLLRLASKGSMRAGQGGHAYLKEWLWWAGLISMGVGEAANFAAYAFAPATLVTPLGALSVLVSAVLSTYFLNEQLNIHGKVGCLLCILGSTVMVIHAPQEEEVGSLTAMAEKLKDPGFIVFAVCVVGSSLVLIFAVAPRFGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFSGTAVLKEPLFWSLVICLVICVSVQINYLNRALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMT 273
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Match: zgc:101583 (magnesium transporter NIPA2 [Source:NCBI gene;Acc:101155856])

HSP 1 Score: 197.978 bits (502), Expect = 5.455e-59
Identity = 136/270 (50.37%), Postives = 195/270 (72.22%), Query Frame = 2 
Query:  164 NMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            N  NFYIGL LA+ S   +G S+I+KK  L RL S+G  RAG GG+ YLK+W+WW GL+ M  GE  N  AY FAPA+LVTPLGALSVLV+A LS+  L+E LN+ GK+GC++C+ GST++V+HAP+E+ V S+  ++E+    GFI+F    +    +L+  + PR+G+KN L+YILI S IGSLSV  VKG+G+ +KE   GT V    +F+ ++I L++ + +Q+NYLN+ALD+FNT+I+TP+ YV FT  V+  S+IL +EW++++
Sbjct:    4 NRVNFYIGLSLAVSSSAFIGASFILKKKGLLRLASKGSMRAGQGGHAYLKEWLWWAGLISMGVGEAANFAAYAFAPATLVTPLGALSVLVSAVLSTYFLNEQLNIHGKVGCLLCILGSTVMVIHAPQEEEVGSLTAMAEKLKDPGFIVFAVCVVGSSLVLIFAVAPRFGQKNVLVYILICSVIGSLSVSCVKGLGIGIKELFSGTAVLKEPLFWSLVICLVICVSVQINYLNRALDIFNTSIVTPIYYVFFTTSVMACSAILFKEWLRMT 273
[Close]
BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Match: nipa2 (NIPA magnesium transporter 2 [Source:NCBI gene;Acc:101168859])

HSP 1 Score: 193.741 bits (491), Expect = 2.400e-57
Identity = 139/263 (52.85%), Postives = 192/263 (73.00%), Query Frame = 2 
Query:  173 NFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGK-RAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEW 958
            +FYIGLGLAI S   +G S+I+KK  L RL  +G  RAG GG+ YLK+W+WW GLL M AGE  N  AY FAPA+LVTPLGALSVLV+A LSS  L E LNL GK+GCM+ + GST +V+HAPKE+ ++S+  +S++ +  GF++F  L +++  I +  +GPR+G+ N L+YI I S IG+LSV  VKG+G+ +KEAI GT+V    + +V++ SL+  +  Q+NYLNKALD+FNT+++TP+ YV FT  V+  S+IL +EW
Sbjct:    9 DFYIGLGLAISSSIFIGGSFILKKKGLLRLAKKGSTRAGQGGHAYLKEWLWWAGLLSMGAGEAANFAAYAFAPATLVTPLGALSVLVSAVLSSYFLTERLNLHGKLGCMLSILGSTTMVIHAPKEEEISSLEHMSKKLVDPGFVVFATLVVIVALIFIFVVGPRHGQTNILVYITICSVIGALSVSCVKGLGIAIKEAIAGTNVVKNPLAWVLLFSLVGCVSTQINYLNKALDIFNTSLVTPIYYVFFTTSVLTCSAILFKEW 271
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Match: nipa1 (NIPA magnesium transporter 1 [Source:NCBI gene;Acc:101168614])

HSP 1 Score: 132.109 bits (331), Expect = 1.174e-34
Identity = 104/278 (37.41%), Postives = 167/278 (60.07%), Query Frame = 2 
Query:  152 DEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKG--THVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
             E P  ++   G+ +A+LS FV G +++++K  + R  SR K     G  Y+ D +WW G L M  G+I N +AY  AP  +VTPLGAL VL  A L+S IL EHLN+LGK+GC++C CGS ++++H+PK +   S  E  ER     F+ ++ L ++++ +L++++ P +G  N L+Y+ I S +G+ +V   KG+G+   +A  G         +   ++ +L + +L Q  ++NKAL+ F++NI   + YV FT  VI AS+IL +EW  L+  D
Sbjct:    5 SELPVASSETAGIVIAVLSSFVNGCTFVLQKKGILR--SREK-----GVSYVTDLVWWSGTLCMIIGQIGNFLAYNVAPVVIVTPLGALGVLFGAVLASWILEEHLNILGKLGCLLCCCGSIVLIIHSPKAE-ATSRAEFEERLFDPVFVTYILLVVVLLIVLIVWIVPAHGTSNILVYVSICSLLGNFTVPCSKGLGLVAPDAFGGGAASGEALALLLGLLGTLAVSILTQFYFINKALECFSSNIFDAIYYVAFTSSVIFASAILFKEWTALAVTD 274
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BLAST of Magnesium transporter NIPA2 vs. Planmine SMEST
Match: SMESG000071002.1 (SMESG000071002.1)

HSP 1 Score: 576.244 bits (1484), Expect = 0.000e+0
Identity = 370/372 (99.46%), Postives = 371/372 (99.73%), Query Frame = 2 
Query:  119 MVVNTSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYXXXXXXXXXXXXXXXXXXXXKDSDVTWNKLKSDFFNNMYKDQSMLLLNNSNERTEINEITVNSGFVDIDEDVIPFLGRSDVKNC 1234
            M VNTSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDWMWWLGLLLMAAGEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHE+LNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFVGLTLLMVFILLLFLGPRYGKKNPLIYILISSSIGSLSVMSVKGIGVCLKEAIKGTHVWTYWIFYVVIISLILGLLIQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYFGIIVGFILIILGFFLLYFFKDSDVTWNKLKSDFFNNMYKDQSMLLLNNSNERTEINEITVNSGFVDIDEDVIPFLGRSDVKNC
Sbjct:    1 MFVNTSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDWMWWLGLLLMAAGEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEYLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFVGLTLLMVFILLLFLGPRYGKKNPLIYILISSSIGSLSVMSVKGIGVCLKEAIKGTHVWTYWIFYVVIISLILGLLIQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYFGIIVGFILIILGFFLLYFFKDSDVTWNKLKSDFFNNMYKDQSMLLLNNSNERTEINEITVNSGFVDIDEDVIPFLGRSDVKNC 372
[Close]
BLAST of Magnesium transporter NIPA2 vs. Planmine SMEST
Match: SMESG000070745.1 (SMESG000070745.1)

HSP 1 Score: 197.978 bits (502), Expect = 1.412e-59
Identity = 130/271 (47.97%), Postives = 196/271 (72.32%), Query Frame = 2 
Query:  167 MTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLISRGKRAGDGGYGYLKDXXXXXXXXXXXXXEIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVD 979
            M +F IGL LA++S F++G S++ KK  L  +   G RAG+GG+GYLK+W+WW+G+ LMA GE +N  AY FAPASLVTPLGALSVLVTA  S+ +L E LN++GK+GC++C+ GS +I+LH P+EQ + S  +L  + +   F+I+ G+ LL+V  L+ F   ++GK +PL+Y++I+ SIGS++V+S KGIGV + E      +++Y  F+V++I++++ +  Q+ +LN+ALD+FN ++ITP++YV FT FV+ ASSI   E    SF D
Sbjct:    1 MDSFLIGLCLALISTFLIGISFVFKKKGLIIISENGTRAGNGGFGYLKEWIWWIGMTLMALGEFLNFAAYSFAPASLVTPLGALSVLVTAIASNHMLSEKLNVIGKLGCVLCITGSIVIILHVPQEQSLKSFEDLEAKLLRKEFLIYCGIILLLVGYLIFFGVRKWGKSSPLVYVIITGSIGSVTVISCKGIGVAVHELFNSKVIFSYPFFWVLLITMLICVFCQLTFLNRALDVFNISVITPILYVVFTSFVLTASSIAFSELAHQSFTD 271
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BLAST of Magnesium transporter NIPA2 vs. Planmine SMEST
Match: SMESG000039144.1 (SMESG000039144.1)

HSP 1 Score: 66.6254 bits (161), Expect = 8.858e-12
Identity = 60/206 (29.13%), Postives = 106/206 (51.46%), Query Frame = 2 
Query:  353 EIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            E+ N VA+G APAS+V PLG  +V+    ++   L E L      G  + L G+ +IV  + + Q + +   L+E  +   F+I+  + ++++  LL+ L  R+   + L+ + I S   S++V++ KG+   L     G +   Y I Y+  + L +   +QV YLN A+ L+ + ++ P  +V FTI  I A      E+  L+
Sbjct:   86 ELGNFVAFGLAPASMVAPLGTTTVIANMVIAVIFLKEKLRPEDIFGTTLALIGACLIVNFSARMQYIMTSSYLTELIVRKPFLIYFSIEMIILVGLLVLLY-RFKVDHILVLLGIGSIFASITVITAKGVSALLTLTFNGQNQMIYPIIYIYTLLLFVTAALQVIYLNMAMQLYYSTVVVPTNFVLFTISAITAGISYYREFANLN 290
[Close]
BLAST of Magnesium transporter NIPA2 vs. Planmine SMEST
Match: SMESG000039144.1 (SMESG000039144.1)

HSP 1 Score: 66.6254 bits (161), Expect = 9.338e-12
Identity = 60/206 (29.13%), Postives = 106/206 (51.46%), Query Frame = 2 
Query:  353 EIINSVAYGFAPASLVTPLGALSVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVELSERFISTGFIIFXXXXXXXXXXXXXXXXPRYGKKNPXXXXXXXXXXXXXXVMSVKGIGVCLKEAIKGTHVWTYWIFYVVXXXXXXXXXXQVNYLNKALDLFNTNIITPLIYVCFTIFVIVASSILLEEWIKLS 970
            E+ N VA+G APAS+V PLG  +V+    ++   L E L      G  + L G+ +IV  + + Q + +   L+E  +   F+I+  + ++++  LL+ L  R+   + L+ + I S   S++V++ KG+   L     G +   Y I Y+  + L +   +QV YLN A+ L+ + ++ P  +V FTI  I A      E+  L+
Sbjct:   84 ELGNFVAFGLAPASMVAPLGTTTVIANMVIAVIFLKEKLRPEDIFGTTLALIGACLIVNFSARMQYIMTSSYLTELIVRKPFLIYFSIEMIILVGLLVLLY-RFKVDHILVLLGIGSIFASITVITAKGVSALLTLTFNGQNQMIYPIIYIYTLLLFVTAALQVIYLNMAMQLYYSTVVVPTNFVLFTISAITAGISYYREFANLN 288
The following BLAST results are available for this feature:
BLAST of Magnesium transporter NIPA2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NIPAL42.956e-6653.33NIPA like domain containing 4 [Source:HGNC Symbol;... [more]
NIPA25.621e-6250.37NIPA magnesium transporter 2 [Source:HGNC Symbol;A... [more]
NIPA25.621e-6250.37NIPA magnesium transporter 2 [Source:HGNC Symbol;A... [more]
NIPA25.621e-6250.37NIPA magnesium transporter 2 [Source:HGNC Symbol;A... [more]
NIPAL48.403e-5847.41NIPA like domain containing 4 [Source:HGNC Symbol;... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nipa-16.699e-7251.96NIPA1 (NonImprinted gene in Prader-Willi/Angelman ... [more]
nipa-11.214e-7151.96NIPA1 (NonImprinted gene in Prader-Willi/Angelman ... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
spict8.165e-5945.07gene:FBgn0032451 transcript:FBtr0080397[more]
spict1.112e-5845.07gene:FBgn0032451 transcript:FBtr0329924[more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nipal44.760e-6045.69NIPA like domain containing 4 [Source:ZFIN;Acc:ZDB... [more]
zgc:1015831.240e-5952.96zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75][more]
zgc:1015831.240e-5952.96zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75][more]
zgc:1015832.925e-5952.59zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75][more]
nipa27.156e-5346.29NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dcbld11.697e-5750.00discoidin, CUB and LCCL domain containing 1 [Sourc... [more]
tomm401.458e-5146.34translocase of outer mitochondrial membrane 40 hom... [more]
nipal45.186e-4850.36NIPA-like domain containing 4 [Source:NCBI gene;Ac... [more]
nipal48.193e-4850.36NIPA-like domain containing 4 [Source:NCBI gene;Ac... [more]
MGC1084294.129e-4347.04MGC108429 protein [Source:NCBI gene;Acc:595009][more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Nipal47.279e-6851.85NIPA-like domain containing 4 [Source:MGI Symbol;A... [more]
Nipa21.902e-6249.26non imprinted in Prader-Willi/Angelman syndrome 2 ... [more]
Nipa21.902e-6249.26non imprinted in Prader-Willi/Angelman syndrome 2 ... [more]
Nipa21.902e-6249.26non imprinted in Prader-Willi/Angelman syndrome 2 ... [more]
Nipa21.902e-6249.26non imprinted in Prader-Willi/Angelman syndrome 2 ... [more]
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BLAST of Magnesium transporter NIPA2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8BZF2|NIPA4_MOUSE5.092e-6751.85Magnesium transporter NIPA4 OS=Mus musculus OX=100... [more]
sp|Q0D2K0|NIPA4_HUMAN1.420e-6553.33Magnesium transporter NIPA4 OS=Homo sapiens OX=960... [more]
sp|Q9JJC8|NIPA2_MOUSE1.331e-6149.26Magnesium transporter NIPA2 OS=Mus musculus OX=100... [more]
sp|Q5R7Q3|NIPA2_PONAB2.700e-6150.37Magnesium transporter NIPA2 OS=Pongo abelii OX=960... [more]
sp|Q8N8Q9|NIPA2_HUMAN2.700e-6150.37Magnesium transporter NIPA2 OS=Homo sapiens OX=960... [more]
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BLAST of Magnesium transporter NIPA2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NX632.087e-7254.41Magnesium transporter NIPA2 OS=Schistocephalus sol... [more]
A0A3P6I4V24.214e-7252.20Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5K3FBX14.516e-7252.52Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A0X3NX999.825e-7254.41Magnesium transporter NIPA2 OS=Schistocephalus sol... [more]
A0A267EJX42.154e-7153.36Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nipal43.588e-6147.13magnesium transporter NIPA2-like [Source:NCBI gene... [more]
nipa23.569e-5350.19NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-... [more]
nipa11.385e-4041.48NIPA magnesium transporter 1 [Source:NCBI gene;Acc... [more]
zgc:1015831.964e-1747.37zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75][more]
NIPAL23.459e-1432.70NIPA like domain containing 2 [Source:NCBI gene;Ac... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
nipa25.690e-6449.39NIPA magnesium transporter 2 [Source:ZFIN;Acc:ZDB-... [more]
zgc:1015832.049e-4746.69zgc:101583 [Source:ZFIN;Acc:ZDB-GENE-041212-75][more]
ENSPMAT00000010214.14.806e-3444.39pep scaffold:Pmarinus_7.0:GL484904:7619:12052:-1 g... [more]
nipa19.627e-2136.45NIPA magnesium transporter 1 [Source:ZFIN;Acc:ZDB-... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO316535.759e-6450.95Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO301413.405e-1328.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO451273.736e-1328.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Magnesium transporter NIPA2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nipal41.002e-5946.85magnesium transporter NIPA2 [Source:NCBI gene;Acc:... [more]
zgc:1015835.455e-5950.37magnesium transporter NIPA2 [Source:NCBI gene;Acc:... [more]
zgc:1015835.455e-5950.37magnesium transporter NIPA2 [Source:NCBI gene;Acc:... [more]
nipa22.400e-5752.85NIPA magnesium transporter 2 [Source:NCBI gene;Acc... [more]
nipa11.174e-3437.41NIPA magnesium transporter 1 [Source:NCBI gene;Acc... [more]
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BLAST of Magnesium transporter NIPA2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000071002.10.000e+099.46SMESG000071002.1[more]
SMESG000070745.11.412e-5947.97SMESG000070745.1[more]
SMESG000039144.18.858e-1229.13SMESG000039144.1[more]
SMESG000039144.19.338e-1229.13SMESG000039144.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025679 ID=SMED30025679|Name=Magnesium transporter NIPA2|organism=Schmidtea mediterranea sexual|type=transcript|length=1330bp
TAGAAATCATGATCTTCAAATAATGAAATTAATTTCTTTAATTTGTGAAA
GAATAGTTTTTAATTTAAAAAATCATTAATCATTTAGATAATTATCTATT
AGTAAAGTTAAAATTAAAATGGTTGTGAATACGTCCTGTTGTACAGTTAC
CGATGAACATCCAAACATGACCAATTTTTATATTGGATTAGGATTAGCGA
TCTTATCATGTTTTGTAATGGGTTGGAGTTATATAGTGAAAAAATTATCT
CTTAATCGATTGATTTCACGCGGGAAAAGAGCAGGAGATGGCGGTTATGG
ATATTTGAAAGATTGGATGTGGTGGTTAGGATTACTATTAATGGCAGCTG
GTGAAATAATTAATTCCGTGGCATATGGATTTGCACCAGCTTCTTTAGTT
ACTCCTCTTGGAGCATTGAGTGTGTTGGTTACTGCATATTTAAGTTCAAA
AATACTGCATGAACATTTGAATTTACTGGGGAAAATCGGTTGTATGATTT
GCTTGTGTGGATCTACAATAATTGTGTTGCACGCACCGAAAGAACAAATT
GTTAATTCAATCGTCGAACTTAGTGAAAGATTTATTAGCACAGGTTTTAT
TATTTTTGTCGGTCTAACATTGCTGATGGTTTTCATTTTACTACTTTTTC
TTGGTCCTAGATATGGAAAGAAAAATCCACTAATTTATATATTAATCAGC
TCAAGTATCGGTTCTCTTTCAGTAATGAGTGTCAAAGGAATCGGCGTGTG
CTTAAAAGAAGCAATTAAAGGAACTCATGTTTGGACATATTGGATTTTCT
ATGTTGTAATTATTAGTCTTATTTTGGGATTACTTATTCAAGTCAATTAT
TTAAATAAAGCACTGGATTTATTCAACACAAATATTATCACTCCGCTTAT
TTACGTTTGTTTCACCATATTTGTTATTGTTGCCAGCTCCATTTTGCTTG
AAGAGTGGATAAAATTATCATTTGTGGATTATTTCGGAATAATTGTCGGA
TTCATCCTCATCATTTTAGGATTTTTCCTTTTATATTTTTTCAAAGATTC
AGATGTTACTTGGAATAAATTGAAATCAGATTTCTTCAACAATATGTACA
AAGATCAAAGTATGTTATTGTTGAATAATTCTAACGAAAGAACAGAAATC
AATGAAATAACTGTGAATTCTGGATTTGTTGATATTGATGAAGATGTTAT
ACCCTTTCTTGGACGATCAGATGTAAAGAATTGCTAGATTATTTCAGACA
CGTCAATATTGTAAAAAAACTTGTACATAGAAAACTATATTTTCTGTGTG
TGATATTTTCAAAGAAATTAAAAGCCATTC
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protein sequence of SMED30025679-orf-1

>SMED30025679-orf-1 ID=SMED30025679-orf-1|Name=SMED30025679-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=373bp
MVVNTSCCTVTDEHPNMTNFYIGLGLAILSCFVMGWSYIVKKLSLNRLIS
RGKRAGDGGYGYLKDWMWWLGLLLMAAGEIINSVAYGFAPASLVTPLGAL
SVLVTAYLSSKILHEHLNLLGKIGCMICLCGSTIIVLHAPKEQIVNSIVE
LSERFISTGFIIFVGLTLLMVFILLLFLGPRYGKKNPLIYILISSSIGSL
SVMSVKGIGVCLKEAIKGTHVWTYWIFYVVIISLILGLLIQVNYLNKALD
LFNTNIITPLIYVCFTIFVIVASSILLEEWIKLSFVDYFGIIVGFILIIL
GFFLLYFFKDSDVTWNKLKSDFFNNMYKDQSMLLLNNSNERTEINEITVN
SGFVDIDEDVIPFLGRSDVKNC*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002032epidermal cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR008521Mg_trans_NIPA
IPR003133T_Ag_DNA-bd
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: molecular function
TermDefinition
GO:0015095magnesium ion transmembrane transporter activity
GO:0003688DNA replication origin binding
Vocabulary: biological process
TermDefinition
GO:0015693magnesium ion transport
GO:0006260DNA replication
GO:1903830magnesium ion transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008521Magnesium transporter NIPAPFAMPF05653Mg_trans_NIPAcoord: 19..310
e-value: 5.1E-102
score: 341.0
IPR008521Magnesium transporter NIPAPANTHERPTHR12570UNCHARACTERIZEDcoord: 7..327
NoneNo IPR availablePANTHERPTHR12570:SF7MAGNESIUM TRANSPORTER NIPA4coord: 7..327
NoneNo IPR availableSUPERFAMILYSSF103481Multidrug resistance efflux transporter EmrEcoord: 65..139
NoneNo IPR availableTMHMMTMhelixcoord: 93..110
NoneNo IPR availableTMHMMTMhelixcoord: 254..276
NoneNo IPR availableTMHMMTMhelixcoord: 20..39
NoneNo IPR availableTMHMMTMhelixcoord: 154..176
NoneNo IPR availableTMHMMTMhelixcoord: 286..308
NoneNo IPR availableTMHMMTMhelixcoord: 220..242
NoneNo IPR availableTMHMMTMhelixcoord: 188..210
NoneNo IPR availableTMHMMTMhelixcoord: 66..88
NoneNo IPR availableTMHMMTMhelixcoord: 117..139