pim-1

Overview
Namepim-1 (AFJ24828.1)
Smed IDSMED30025671
Length (bp)1548
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of pim-1 (SMED30025671) t-SNE clustered cells

Violin plots show distribution of expression levels for pim-1 (SMED30025671) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of pim-1 (SMED30025671) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for pim-1 (SMED30025671) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025671

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X2 cellSMED30025671SMESG000017137.1 SmedASXL_019309SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
nervous systemSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025671SMESG000017137.1 dd_Smed_v4_4012_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of pim-1 vs. Ensembl Human
Match: PIM1 (Pim-1 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8986])

HSP 1 Score: 245.743 bits (626), Expect = 6.649e-77
Identity = 129/277 (46.57%), Postives = 172/277 (62.09%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R+SD L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L EE A  FF Q++E ++ CH   VLHRDIKDENIL+D N   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI  CL   PS R    EI NHPW+Q
Sbjct:   18 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQ 291
[Close]
BLAST of pim-1 vs. Ensembl Human
Match: PIM2 (Pim-2 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8987])

HSP 1 Score: 241.121 bits (614), Expect = 4.184e-75
Identity = 123/265 (46.42%), Postives = 165/265 (62.26%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPV---KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            E F + Y+    +G+GGFGTVF G RL+DRL+V IK I   ++   +   + ++  PLEVALL K        GVI +L ++++  ++G+ L++ R     DLFDYI+    L E  +  FF Q++  ++ CH + V+HRDIKDENIL+D       LIDFGSGA L  + Y +FDGTRVYSPPEWI  H Y+     VWSLG+LL+DMVCGDIPF  D +IL  +L +   VS DC  LI +CL   PS R +L EI   PW+Q
Sbjct:   26 EAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLG-WSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFET--QEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQ 287
[Close]
BLAST of pim-1 vs. Ensembl Human
Match: PIM3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:19310])

HSP 1 Score: 233.032 bits (593), Expect = 9.691e-72
Identity = 124/266 (46.62%), Postives = 171/266 (64.29%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKCRPV---KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            +E F   YQ    +G GGFGTV+ G+R++D L V +K +  +++T+   W +   A +PLEV LL K       +GVI +L +++     G+ L++ R     DLFD+I+    L E  A  FF Q++  ++ CH   V+HRDIKDEN+LVD  +  + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLGVLL+DMVCGDIPF  D++IL G+L +R  VS +C+ LI  CL   PS R +L++I+ HPW+
Sbjct:   33 KESFEKAYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTE---WGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFER--PDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWM 293
[Close]
BLAST of pim-1 vs. Ensembl Human
Match: PIM2 (Pim-2 proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:8987])

HSP 1 Score: 159.073 bits (401), Expect = 5.943e-46
Identity = 74/143 (51.75%), Postives = 93/143 (65.03%), Query Frame = 1 
Query:  562 LIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVS 990
            L++ R     DLFDYI+    L E  +  FF Q++  ++ CH + V+HRDIKDENIL+D       LIDFGSGA L  + Y +FDGTRVYSPPEWI  H Y+     VWSLG+LL+DMVCGDIPF  D +IL  +L +   VS
Sbjct:    2 LVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVS 144
[Close]
BLAST of pim-1 vs. Ensembl Human
Match: NUAK2 (NUAK family kinase 2 [Source:HGNC Symbol;Acc:HGNC:29558])

HSP 1 Score: 133.65 bits (335), Expect = 1.070e-32
Identity = 94/271 (34.69%), Postives = 141/271 (52.03%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG------SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD------QILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
             R  Y+  E +G+G +G V K    S RL V IK I   KI D        + I  E+ +++       +I +   +++  K    +I+   A   DL+DYIS  + LSE +A  FFRQI+  +  CHQ +V+HRD+K ENIL+D N + + + DFG       G FL+T     F G+ +Y+ PE +    Y G +++ WSLGVLL+ +V G +PF+  D      QI NG  +     S  C  LI   L  +P+ R  L ++++H WV
Sbjct:   49 LRHRYEFLETLGKGTYGKVKKARESSGRL-VAIKSIRKDKIKDEQDL----MHIRREIEIMSSLN-HPHIIAIHEVFENSSK---IVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGN-IKIADFGLSNLYHQGKFLQT-----FCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTRRATLEDVASHWWV 303
[Close]
BLAST of pim-1 vs. Ensembl Celegans
Match: prk-2 (Serine/threonine-protein kinase prk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q20443])

HSP 1 Score: 220.705 bits (561), Expect = 4.129e-66
Identity = 114/292 (39.04%), Postives = 168/292 (57.53%), Query Frame = 1 
Query:  268 LNKIEFFN-----------GEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQI----LNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            L  ++FFN           G   F+ +Y+   E+G+GGFG V++  R  D   V +KFI    + +  +   +   +P+E+ +LAKC  V+GVI +L +Y     +G+ ++M R    +D+FD+I     +SE+ A F FRQI   + +C Q +VLHRD+KDENI++D  T    LIDFG+   L+   Y +F GTR+Y PPEW  +  Y G +  VWSLGVLL++ + G +PF  +  I    L G L +   VSA+ +DLI KCL  DP  R +L  I NHPWV++  L+
Sbjct:    4 LASLQFFNLKLLLNGESSRGFSKFKKNYKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQ--VPMEICMLAKCSKVRGVIRLLDWYSIP--EGFLIVMERPYPCIDMFDFIKGQGKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQYSDFQGTRLYCPPEWFLHSLYLGREAAVWSLGVLLYNSLNGRLPFRNEKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWVKQQTLS 291
[Close]
BLAST of pim-1 vs. Ensembl Celegans
Match: prk-2 (Serine/threonine-protein kinase prk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q20443])

HSP 1 Score: 220.705 bits (561), Expect = 4.129e-66
Identity = 114/292 (39.04%), Postives = 168/292 (57.53%), Query Frame = 1 
Query:  268 LNKIEFFN-----------GEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQI----LNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            L  ++FFN           G   F+ +Y+   E+G+GGFG V++  R  D   V +KFI    + +  +   +   +P+E+ +LAKC  V+GVI +L +Y     +G+ ++M R    +D+FD+I     +SE+ A F FRQI   + +C Q +VLHRD+KDENI++D  T    LIDFG+   L+   Y +F GTR+Y PPEW  +  Y G +  VWSLGVLL++ + G +PF  +  I    L G L +   VSA+ +DLI KCL  DP  R +L  I NHPWV++  L+
Sbjct:    4 LASLQFFNLKLLLNGESSRGFSKFKKNYKLKAELGRGGFGVVYRAVRTCDNALVAVKFIERSNVKEWARINGEQ--VPMEICMLAKCSKVRGVIRLLDWYSIP--EGFLIVMERPYPCIDMFDFIKGQGKISEDMARFLFRQIAVTVHECVQNRVLHRDLKDENIVIDLVTGSTKLIDFGAATVLRRSQYSDFQGTRLYCPPEWFLHSLYLGREAAVWSLGVLLYNSLNGRLPFRNEKDICTAHLLGPLPFFVPVSAEVKDLISKCLTFDPFQRCSLEAILNHPWVKQQTLS 291
[Close]
BLAST of pim-1 vs. Ensembl Celegans
Match: prk-1 (Pim (Mammalian oncogene) Related Kinase [Source:UniProtKB/TrEMBL;Acc:K8ESD7])

HSP 1 Score: 183.726 bits (465), Expect = 8.739e-53
Identity = 97/262 (37.02%), Postives = 154/262 (58.78%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLE-VIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIE-ILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            F+  Y+  +EIG+GGFG V++ T   D  + V +KF+ +K +  ++    + L IP EV  L  C  + GVI +L ++ +   KG+ ++M R A  +DLFD +S    L+E+   F F+Q+I  +     +  +LHRDIKDEN++V+ NT  V L+DFG+ A+ +    + F GTR Y PPEW ++  Y   +   WSLGVLLF ++ G +PF  + QI  G +K+   +S +   L++ CL    S R +L +I+ HPW++
Sbjct:   30 FKRKYEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVR-SWTMTCRQL-IPSEVCHLETCEDIPGVIKILDWFAN--SKGFLIVMERPANCMDLFDMVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGVLLFILLTGKLPFRNEIQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWME 287
[Close]
BLAST of pim-1 vs. Ensembl Celegans
Match: prk-1 (Pim (Mammalian oncogene) Related Kinase [Source:UniProtKB/TrEMBL;Acc:K8ESD7])

HSP 1 Score: 187.193 bits (474), Expect = 2.232e-52
Identity = 97/262 (37.02%), Postives = 154/262 (58.78%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSD-RLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIE-ILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            F+  Y+  +EIG+GGFG V++ T   D +  V +KF+ +K +  ++    + L IP EV  L  C  + GVI +L ++ +   KG+ ++M R A  +DLFD +S    L+E+   F F+Q+I  +     +  +LHRDIKDEN++V+ NT  V L+DFG+ A+ +    + F GTR Y PPEW ++  Y   +   WSLGVLLF ++ G +PF  + QI  G +K+   +S +   L++ CL    S R +L +I+ HPW++
Sbjct:   30 FKRKYEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVR-SWTMTCRQL-IPSEVCHLETCEDIPGVIKILDWFAN--SKGFLIVMERPANCMDLFDMVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGVLLFILLTGKLPFRNEIQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWME 287
[Close]
BLAST of pim-1 vs. Ensembl Celegans
Match: prk-1 (Pim (Mammalian oncogene) Related Kinase [Source:UniProtKB/TrEMBL;Acc:K8ESD7])

HSP 1 Score: 186.808 bits (473), Expect = 4.641e-52
Identity = 97/262 (37.02%), Postives = 154/262 (58.78%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSD-RLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIE-ILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            F+  Y+  +EIG+GGFG V++ T   D +  V +KF+ +K +  ++    + L IP EV  L  C  + GVI +L ++ +   KG+ ++M R A  +DLFD +S    L+E+   F F+Q+I  +     +  +LHRDIKDEN++V+ NT  V L+DFG+ A+ +    + F GTR Y PPEW ++  Y   +   WSLGVLLF ++ G +PF  + QI  G +K+   +S +   L++ CL    S R +L +I+ HPW++
Sbjct:   53 FKRKYEVLDEIGRGGFGIVYEATTRQDGQQPVAVKFVQHKHVR-SWTMTCRQL-IPSEVCHLETCEDIPGVIKILDWFAN--SKGFLIVMERPANCMDLFDMVSVHGPLNEDMGKFIFKQVITTVFNMYSKHGLLHRDIKDENLIVNMNTGEVKLVDFGATAYAEKATKKEFQGTRSYCPPEWFRDQLYLPLEATSWSLGVLLFILLTGKLPFRNEIQICLGNVKFPPDLSKEVCQLVKSCLTTSTSARASLAQIAAHPWME 310
[Close]
BLAST of pim-1 vs. Ensembl Fly
Match: Pask (gene:FBgn0034950 transcript:FBtr0072160)

HSP 1 Score: 155.606 bits (392), Expect = 5.827e-40
Identity = 89/276 (32.25%), Postives = 155/276 (56.16%), Query Frame = 1 
Query:  280 EFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNP 1101
            E + G+  +  +Y    +IG+G +G V    R SDRL VI KFI  +K+   +  K+++   +P+E+ LL      K ++ +L  +++D    + L+M +    +DL+ +I R   + E+  ++ FRQ+ + +   H+QK+LHRDIKDENI++D+N   + LIDFGS  F++    +  F GT  Y  PE +  + Y G +LE+W+LGV L+ ++  + PF   ++ L  +++    VS     L+   L  DP YR  ++++   PW+ +  +NP
Sbjct:  566 ELYLGD--YSKYYTSIRQIGRGAYGYVNMAFRNSDRLLVITKFILKEKLCSQFMVKSRDCKEVPIEIHLLQTLNH-KNIVSVLDVFEND--LFYQLVMEKHGSGMDLWTFIERRPLMDEKLGSYIFRQVADAVNYLHEQKILHRDIKDENIIIDQNFT-IKLIDFGSATFMEEGKFFSTFYGTTEYCSPEVLAGNRYVGPELEIWALGVTLYVLMFFENPFIDVEETLKAEIQIPKAVSEQLSRLLSSMLNKDPKYRCTMHQLITDPWLTQ-EVNP 834
[Close]
BLAST of pim-1 vs. Ensembl Fly
Match: sff (gene:FBgn0036544 transcript:FBtr0334071)

HSP 1 Score: 134.035 bits (336), Expect = 6.631e-33
Identity = 86/271 (31.73%), Postives = 144/271 (53.14%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG------SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            F   Y+  + +G+G  G V  G       +V IK I+ +K++++   K +      E+A++ K      V+ +   Y  + KK  YLI+  ++   +LFDY+ +   L+ ++A  FFRQII  L  CH   + HRD+K EN+L+DE  + + + DFG      +G+ L+T       G+  Y+ PE I+   Y+G K +VWS GV+L+ ++ G +PF+ D      +++  G     H V  DC+ L+   ++ +P  R+ L EI+ HPWV
Sbjct:   14 FVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVER-----EIAIM-KLIDHPHVLGLSDVY--ENKKYLYLILEHVSGG-ELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETS-----CGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV 269
[Close]
BLAST of pim-1 vs. Ensembl Fly
Match: sff (gene:FBgn0036544 transcript:FBtr0089527)

HSP 1 Score: 134.035 bits (336), Expect = 6.960e-33
Identity = 86/271 (31.73%), Postives = 144/271 (53.14%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG------SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            F   Y+  + +G+G  G V  G       +V IK I+ +K++++   K +      E+A++ K      V+ +   Y  + KK  YLI+  ++   +LFDY+ +   L+ ++A  FFRQII  L  CH   + HRD+K EN+L+DE  + + + DFG      +G+ L+T       G+  Y+ PE I+   Y+G K +VWS GV+L+ ++ G +PF+ D      +++  G     H V  DC+ L+   ++ +P  R+ L EI+ HPWV
Sbjct:   14 FVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVER-----EIAIM-KLIDHPHVLGLSDVY--ENKKYLYLILEHVSGG-ELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETS-----CGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV 269
[Close]
BLAST of pim-1 vs. Ensembl Fly
Match: sff (gene:FBgn0036544 transcript:FBtr0334070)

HSP 1 Score: 134.035 bits (336), Expect = 7.018e-33
Identity = 86/271 (31.73%), Postives = 144/271 (53.14%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG------SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            F   Y+  + +G+G  G V  G       +V IK I+ +K++++   K +      E+A++ K      V+ +   Y  + KK  YLI+  ++   +LFDY+ +   L+ ++A  FFRQII  L  CH   + HRD+K EN+L+DE  + + + DFG      +G+ L+T       G+  Y+ PE I+   Y+G K +VWS GV+L+ ++ G +PF+ D      +++  G     H V  DC+ L+   ++ +P  R+ L EI+ HPWV
Sbjct:   14 FVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSESVLMKVER-----EIAIM-KLIDHPHVLGLSDVY--ENKKYLYLILEHVSGG-ELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETS-----CGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDNLRQLLEKVKRGVFHIPHFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV 269
[Close]
BLAST of pim-1 vs. Ensembl Fly
Match: CG8485 (gene:FBgn0033915 transcript:FBtr0087572)

HSP 1 Score: 132.88 bits (333), Expect = 1.660e-32
Identity = 94/287 (32.75%), Postives = 140/287 (48.78%), Query Frame = 1 
Query:  316 YQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVI--DMLAFYKS-DGKKGWYLIMNRIAKFVDLFDYISRAKY-LSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPF------NTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANY-PL 1140
            Y   E +G G F  V     +    +V +K +   K+ D  K             L  + R +K V   +++  Y+  D +   YL++  +    DL+DYI +    LSEE A  +FRQI+  +  CHQ  V+HRD+K EN++  E    V L DFG S  FL       F G+  YS PE +    Y+   +++WSLGV+L+ +VCG  PF       T   I++ K      VS DCRDLI   L  DP  R  + EI++  W++   ++   STT T+ ++ PL
Sbjct:   20 YDLEETLGSGHFAVVKLARHVFTGAKVAVKVVDKTKLDDVSK-----------AHLFQEVRCMKLVQHPNVVRLYEVIDTQTKLYLVL-ELGDGGDLYDYIMKHDSGLSEELARKYFRQILRAITYCHQLHVVHRDLKPENVVFFEKLGLVKLTDFGFSNKFLPGQKLETFCGSLAYSAPEILLGDSYDAPAVDIWSLGVILYMLVCGQAPFEKANDSETLTMIMDCKYTVPSHVSTDCRDLIASMLVRDPKKRATVEEIASSAWLKP--IDEPDSTTSTSEHFLPL 292
[Close]
BLAST of pim-1 vs. Ensembl Zebrafish
Match: pim1 (Pim-1 proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-061013-139])

HSP 1 Score: 240.35 bits (612), Expect = 6.381e-75
Identity = 121/264 (45.83%), Postives = 168/264 (63.64%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            +E F   YQ    +G GGFGTV+ G R++D   V IK ++  ++T+ +        +P+E+ LL K     +GVI ML +Y+      + ++M R     DLFD+I+    L EE A  FFRQ++E ++ CH   V+HRDIKDENIL+D  T  + LIDFGSGA LK   Y +FDGTRVYSPPEWIK H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  +S +C+ LI+ CL   P+ R +  +I NH W+Q
Sbjct:   28 KEPFDKVYQVGTVLGSGGFGTVYAGLRIADGAPVAIKHVAKDRVTE-WGELPNGARVPMEIVLLKKVGTGFRGVIKMLDWYER--PDSFIIVMERPEVVKDLFDFITEKGALPEELARNFFRQVLEAVRHCHNSGVVHRDIKDENILIDLRTGDLKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIKFHRYHGRSATVWSLGILLYDMVCGDIPFEQDEEIVRGQVLFRRRISTECQQLIKWCLALRPADRPSFEDIINHDWMQ 288
[Close]
BLAST of pim-1 vs. Ensembl Zebrafish
Match: pim3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-050809-111])

HSP 1 Score: 238.424 bits (607), Expect = 3.451e-74
Identity = 134/289 (46.37%), Postives = 179/289 (61.94%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKCRPV-KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSN 1158
            E F   Y     +G GGFGTV+ GTR+SD L V IK ++ +++T+   W   N + IPLE+ LL K     +GVI ++ +Y+     GW +IM R     DLFDYI+    L E+ A  FFRQ++E ++ C+   V+HRDIKDEN+LVD  T  + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLGVLL+DMVCGDIPF  D++IL G+L +R  VS  C+ LI+ CL   PS R  L +I  H W++    NP  + ++    + +S    N
Sbjct:   35 EPFEKVYHVGSVLGSGGFGTVYAGTRISDALPVAIKHVAKERVTE---WGTINGSLIPLEIVLLKKVGSTFQGVIKLIDWYER--PDGWLIIMERPEMVKDLFDYITEKGALDEDTARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGDLKLIDFGSGAILKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEHDEEILRGRLFFRRRVSPVCQQLIKWCLCLRPSDRPTLEQIFEHQWMRTEE-NPKTAESVNITLHTISTEAGN 317
[Close]
BLAST of pim-1 vs. Ensembl Zebrafish
Match: pim2 (Pim-2 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:58054])

HSP 1 Score: 231.106 bits (588), Expect = 2.030e-71
Identity = 121/286 (42.31%), Postives = 169/286 (59.09%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALL-------AKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            D L  ++  NG+E F   Y     +G GGFG+V+ G R+SD  +V IK IS  +I    K   +   +P E+ALL             +G+I ML +++  G++ + ++  +     DLFD+I+    L E  A  F +Q+IE ++ CH + ++HRDIKDENILVD  T  + +IDFGSGA LK   Y +F+GTRVYSPPEWI  H Y+   L VWSLGVLL+DMVCGDIPF  D  I+  K  +   +S DCR LI  CL  +P  R +L +I  HPW+ +  ++
Sbjct:   12 DQLEILKAKNGKEHFEKQYTMGNLLGSGGFGSVYSGHRISDGQKVAIKQISRDRIQQWSKMPGEVNPVPNEIALLQSLGGGSGSVPGHRGIIRMLDWFEIPGQE-YLIVFEKPQHCQDLFDFITERGALDESLARRFLKQVIEAVQFCHSKGIVHRDIKDENILVDTRTGDIKVIDFGSGATLKDSMYTDFEGTRVYSPPEWILYHKYHALPLTVWSLGVLLYDMVCGDIPFEQDTDIVKAKPSFNKRISNDCRSLICSCLSFNPGDRPSLEQILQHPWMMESSVD 296
[Close]
BLAST of pim-1 vs. Ensembl Zebrafish
Match: pimr54 (Pim proto-oncogene, serine/threonine kinase, related 54 [Source:ZFIN;Acc:ZDB-GENE-070912-425])

HSP 1 Score: 184.111 bits (466), Expect = 2.866e-53
Identity = 100/263 (38.02%), Postives = 150/263 (57.03%), Query Frame = 1 
Query:  307 RSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCR--PV-KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILN-GKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            R  Y     +G+GGFG+VF G R SD L V IK++S K+ TDT         +PLEVAL+ +    PV   V+ +L ++  D ++ + LI+ R A   DL  +      L E  A     Q+I  LK C  ++VLHRD+K EN+L+  ++  + L+DFG G  +K   YR F GT  ++PPEW ++H Y+   L VWS+GV L++++C   PF    ++ +  +L +   +S +CR LI  CL   P+ R +L+EI  HPW+Q
Sbjct:   75 RDQYAKGPLLGRGGFGSVFAGIRRSDGLPVAIKYVS-KEPTDTRLKVDGQGRLPLEVALMTRVSSAPVCPSVLQLLDWF--DHRRRYVLILERPAPCQDLQSFCEENGCLDEPLAKKVLVQLIAALKHCESRRVLHRDVKPENLLISTDSHDIKLLDFGCGDLMKDSAYRYFAGTPAFAPPEWFRHHRYHASPLTVWSIGVTLYNILCDCFPFRGAQRVTSKSRLHFPRKLSTECRQLIRWCLSAAPADRPSLDEIERHPWLQ 334
[Close]
BLAST of pim-1 vs. Ensembl Zebrafish
Match: pimr49 (Pim proto-oncogene, serine/threonine kinase, related 49 [Source:ZFIN;Acc:ZDB-GENE-070912-459])

HSP 1 Score: 182.956 bits (463), Expect = 9.735e-53
Identity = 99/263 (37.64%), Postives = 150/263 (57.03%), Query Frame = 1 
Query:  307 RSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCR--PV-KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILN-GKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            R  Y     +G+GGFG+VF G R SD L V IK++S K+ TDT         +PLEVAL+ +    PV   V+ +L ++  D ++ + LI+ R A   DL  +      L E  A     Q+I  LK C  ++VLHRD+K EN+L+  ++  + L+DFG G  +K   YR F GT  ++PPEW ++H Y+   L VWS+GV L++++C   PF    ++ +  +L +   +S +CR LI  CL   P+ R +L++I  HPW+Q
Sbjct:   75 RDQYAKGPLLGRGGFGSVFAGIRRSDGLPVAIKYVS-KEPTDTRLKVDGQGRLPLEVALMTRVSSAPVCPSVLQLLDWF--DHRRRYVLILERPAPCQDLQSFCEENGCLDEPLAKKVLVQLIAALKHCESRRVLHRDVKPENLLISTDSHDIKLLDFGCGDLMKDSAYRYFAGTPAFAPPEWFRHHRYHASPLTVWSIGVTLYNILCDCFPFRGAQRVTSKSRLHFPRKLSTECRQLIRWCLSAAPADRPSLDDIERHPWLQ 334
[Close]
BLAST of pim-1 vs. Ensembl Xenopus
Match: ncbp1 (nuclear cap binding protein subunit 1 [Source:Xenbase;Acc:XB-GENE-5841194])

HSP 1 Score: 256.529 bits (654), Expect = 8.069e-81
Identity = 133/265 (50.19%), Postives = 172/265 (64.91%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQK 1086
            +E F + YQ    IG GGFGTV+ G R+SD+L V IK +S  +I +          +PLE+ LL K     +GVI +L +Y+     G+ +IM R     DLFD+I+    L EE A  FFRQ++E ++ CH   V+HRDIKDENILVD  T  + LIDFGSGA L+   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  DD+IL GK++YR  VS +C+ LIE CL   PS R +L +I  HPW+ +
Sbjct:   49 KEPFENCYQVGPVIGTGGFGTVYSGVRISDKLPVAIKHVSRDRIGEMKHMNGT--LVPLEIYLLKKVSNGCRGVIRLLDWYER--PDGFIIIMERPEPVQDLFDFITERGALGEELATNFFRQVVEAVRHCHSCDVVHRDIKDENILVDLRTAELKLIDFGSGALLRDAVYTDFDGTRVYSPPEWIRFHKYHGRSATVWSLGILLYDMVCGDIPFEHDDEILKGKIQYRCRVSRECQHLIEWCLSKRPSDRPSLEQILAHPWMSQ 309
[Close]
BLAST of pim-1 vs. Ensembl Xenopus
Match: ncbp1 (nuclear cap binding protein subunit 1 [Source:Xenbase;Acc:XB-GENE-5841194])

HSP 1 Score: 255.758 bits (652), Expect = 1.214e-80
Identity = 136/277 (49.10%), Postives = 177/277 (63.90%), Query Frame = 1 
Query:  259 EDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQK 1086
            +DDL  ++     E F + YQ    IG GGFGTV+ G R+SD+L V IK +S  +I +          +PLE+ LL K     +GVI +L +Y+     G+ +IM R     DLFD+I+    L EE A  FFRQ++E ++ CH   V+HRDIKDENILVD  T  + LIDFGSGA L+   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  DD+IL GK++YR  VS +C+ LIE CL   PS R +L +I  HPW+ +
Sbjct:   23 KDDLPAVK-----EPFENCYQVGPVIGTGGFGTVYSGVRISDKLPVAIKHVSRDRIGEMKHMNGT--LVPLEIYLLKKVSNGCRGVIRLLDWYER--PDGFIIIMERPEPVQDLFDFITERGALGEELATNFFRQVVEAVRHCHSCDVVHRDIKDENILVDLRTAELKLIDFGSGALLRDAVYTDFDGTRVYSPPEWIRFHKYHGRSATVWSLGILLYDMVCGDIPFEHDDEILKGKIQYRCRVSRECQHLIEWCLSKRPSDRPSLEQILAHPWMSQ 290
[Close]
BLAST of pim-1 vs. Ensembl Xenopus
Match: PIM3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:100497723])

HSP 1 Score: 244.973 bits (624), Expect = 1.541e-76
Identity = 125/269 (46.47%), Postives = 174/269 (64.68%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKN-LAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHL 1095
            +E F   YQ    +G GGFGTV+ G+R++D L V +K ++ +++TD   W   N + +PLE+ LL K     +GVI +L +Y+     G+ ++M R     DLFDYI+    L E+ A  FFRQ++E ++ C+   V+HRDIKDEN+LVD     + LIDFGSGA LK   Y +FDGTRVYSPPEW++ H Y+G    VWSLGVLL+DMVCGDIPF  D++I+  +L +R  +S +C+ LI+ CL   PS R  L +I +HPW+ K  L
Sbjct:   33 KEPFEKVYQVGSVLGSGGFGTVYSGSRIADGLPVAVKHVAKERVTD---WGTLNGVMVPLEIVLLKKVGTGFRGVIKLLDWYER--ADGFLIVMERPEPVKDLFDYITEKGALDEDTARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRNGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWVRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEIVRVRLYFRRRISTECQQLIKWCLSLRPSDRPTLEQIFDHPWMCKCDL 296
[Close]
BLAST of pim-1 vs. Ensembl Xenopus
Match: PASK (PAS domain containing serine/threonine kinase [Source:NCBI gene;Acc:100488299])

HSP 1 Score: 148.673 bits (374), Expect = 2.940e-38
Identity = 95/278 (34.17%), Postives = 150/278 (53.96%), Query Frame = 1 
Query:  265 DLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGT-RLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDF-VYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQK 1086
            DL  +   NG+   +  YQ    +G+G FG V+    R S + EV++KFI   ++ D    +   L  +  E+A+L++ +    +I ++  +++D    + L+M      +DLFD+I     L E  A++ FRQ++  +   H Q +LHRDIKDENI++    DF + L+DFGS A L     +  F GT  Y  PE +  + Y G +LE+WSLGV L+ ++ G+ PF   D+IL  +L     VS   + LI   L+ DP  R+ L+E+   PWV +
Sbjct:  223 DLQIVGACNGQYALK--YQTVSPLGKGAFGFVWSACGRDSAKEEVVVKFIRKDRVLDDCWVQDPELGKVTQEIAILSRVQ-HPNIIRVVDVFEND--TFFQLVMELHGDGLDLFDFIDSQPSLDEPLASYIFRQLVSAVGYLHNQHILHRDIKDENIII--APDFSIKLVDFGSAAHLHQGTLFSTFCGTTEYCAPEVLLGNPYPGPELEMWSLGVTLYTLIFGENPFCEVDEILEAELNPPFNVSQKLQVLISGLLQRDPEIRMTLDELLRDPWVTQ 493
[Close]
BLAST of pim-1 vs. Ensembl Xenopus
Match: PASK (PAS domain containing serine/threonine kinase [Source:NCBI gene;Acc:100488299])

HSP 1 Score: 150.984 bits (380), Expect = 4.015e-38
Identity = 95/278 (34.17%), Postives = 150/278 (53.96%), Query Frame = 1 
Query:  265 DLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGT-RLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDF-VYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQK 1086
            DL  +   NG+   +  YQ    +G+G FG V+    R S + EV++KFI   ++ D    +   L  +  E+A+L++ +    +I ++  +++D    + L+M      +DLFD+I     L E  A++ FRQ++  +   H Q +LHRDIKDENI++    DF + L+DFGS A L     +  F GT  Y  PE +  + Y G +LE+WSLGV L+ ++ G+ PF   D+IL  +L     VS   + LI   L+ DP  R+ L+E+   PWV +
Sbjct:  874 DLQIVGACNGQYALK--YQTVSPLGKGAFGFVWSACGRDSAKEEVVVKFIRKDRVLDDCWVQDPELGKVTQEIAILSRVQ-HPNIIRVVDVFEND--TFFQLVMELHGDGLDLFDFIDSQPSLDEPLASYIFRQLVSAVGYLHNQHILHRDIKDENIIIAP--DFSIKLVDFGSAAHLHQGTLFSTFCGTTEYCAPEVLLGNPYPGPELEMWSLGVTLYTLIFGENPFCEVDEILEAELNPPFNVSQKLQVLISGLLQRDPEIRMTLDELLRDPWVTQ 1144
[Close]
BLAST of pim-1 vs. Ensembl Mouse
Match: Pim1 (proviral integration site 1 [Source:MGI Symbol;Acc:MGI:97584])

HSP 1 Score: 244.588 bits (623), Expect = 1.450e-76
Identity = 129/286 (45.10%), Postives = 177/286 (61.89%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMAS 1110
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R++D L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L E+ A  FF Q++E ++ CH   VLHRDIKDENIL+D +   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI+ CL   PS R +  EI NHPW+Q   L   AS
Sbjct:   18 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWMQGDLLPQAAS 300
[Close]
BLAST of pim-1 vs. Ensembl Mouse
Match: Pim2 (proviral integration site 2 [Source:MGI Symbol;Acc:MGI:97587])

HSP 1 Score: 240.35 bits (612), Expect = 3.115e-74
Identity = 121/263 (46.01%), Postives = 163/263 (61.98%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPV---KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            F + Y+    +G+GGFGTVF G R++DR +V IK IS  ++   +   + ++  PLEVALL K        GVI +L ++++   +G+ L++ R     DLFDYI+    L E  +  FF Q++  ++ CH + V+HRDIKDENIL+D     + LIDFGSGA L  + Y +FDGTRVYSPPEWI  H Y+     VWSLGVLL+DMVCGDIPF  D +IL  +L +   VS DC  LI +CL   P  R +L EI   PW+Q
Sbjct:   87 FEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLG-WSTVSDSVTCPLEVALLWKVGEGNGHPGVIRLLDWFET--PEGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSIKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGVLLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPCSRPSLEEILLDPWMQ 346
[Close]
BLAST of pim-1 vs. Ensembl Mouse
Match: Pim2 (proviral integration site 2 [Source:MGI Symbol;Acc:MGI:97587])

HSP 1 Score: 240.35 bits (612), Expect = 3.785e-74
Identity = 121/263 (46.01%), Postives = 163/263 (61.98%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPV---KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            F + Y+    +G+GGFGTVF G R++DR +V IK IS  ++   +   + ++  PLEVALL K        GVI +L ++++   +G+ L++ R     DLFDYI+    L E  +  FF Q++  ++ CH + V+HRDIKDENIL+D     + LIDFGSGA L  + Y +FDGTRVYSPPEWI  H Y+     VWSLGVLL+DMVCGDIPF  D +IL  +L +   VS DC  LI +CL   P  R +L EI   PW+Q
Sbjct:   93 FEAEYRLGPLLGKGGFGTVFAGHRVTDRRQVAIKVISRNRVLG-WSTVSDSVTCPLEVALLWKVGEGNGHPGVIRLLDWFET--PEGFMLVLERPMPAQDLFDYITEKGPLGESCSRSFFTQVVAAVQHCHARGVVHRDIKDENILIDLCRGSIKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGVLLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPCSRPSLEEILLDPWMQ 352
[Close]
BLAST of pim-1 vs. Ensembl Mouse
Match: Pim3 (proviral integration site 3 [Source:MGI Symbol;Acc:MGI:1355297])

HSP 1 Score: 235.343 bits (599), Expect = 6.791e-73
Identity = 125/266 (46.99%), Postives = 173/266 (65.04%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKA-KNLAIPLEVALLAKCRPV---KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            +E F   YQ    +G GGFGTV+ G+R++D L V +K +  +++T+   W +   +A+PLEV LL K       +GVI +L +++     G+ L++ R     DLFD+I+    L E  A  FF Q++  ++ CH   V+HRDIKDEN+LVD  +  + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLGVLL+DMVCGDIPF  D++IL G+L +R  VS +C+ LIE CL   PS R +L++I+ HPW+
Sbjct:   33 KESFEKVYQVGAVLGSGGFGTVYAGSRIADGLPVAVKHVVKERVTE---WGSLGGVAVPLEVVLLRKVGAAGGARGVIRLLDWFER--PDGFLLVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHNCGVVHRDIKDENLLVDLRSGELKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGRLFFRRRVSPECQQLIEWCLSLRPSERPSLDQIAAHPWM 293
[Close]
BLAST of pim-1 vs. Ensembl Mouse
Match: Pim1 (proviral integration site 1 [Source:MGI Symbol;Acc:MGI:97584])

HSP 1 Score: 142.124 bits (357), Expect = 3.777e-39
Identity = 82/202 (40.59%), Postives = 111/202 (54.95%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEE--FFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNH 858
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R++D L                        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L E+ A  FF Q++E ++ CH   VLHRDIKDENIL+D +   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H
Sbjct:   14 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNL------------------PPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYH 195
[Close]
BLAST of pim-1 vs. UniProt/SwissProt
Match: sp|P26794|PIM1_RAT (Serine/threonine-protein kinase pim-1 OS=Rattus norvegicus OX=10116 GN=Pim1 PE=1 SV=1)

HSP 1 Score: 246.128 bits (627), Expect = 2.869e-76
Identity = 127/272 (46.69%), Postives = 170/272 (62.50%), Query Frame = 1 
Query:  271 NKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            NK+     +E   S YQ    +G GGFG+V+ G R++D L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L EE A  FF Q++E ++ CH   VLHRDIKDENIL+D N   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI  CL   PS R +  EI NHPW+Q
Sbjct:   23 NKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIVKGQVYFRQRVSSECQHLIRWCLSLRPSDRPSFEEIQNHPWMQ 291
[Close]
BLAST of pim-1 vs. UniProt/SwissProt
Match: sp|P11309|PIM1_HUMAN (Serine/threonine-protein kinase pim-1 OS=Homo sapiens OX=9606 GN=PIM1 PE=1 SV=4)

HSP 1 Score: 245.743 bits (626), Expect = 3.193e-76
Identity = 129/277 (46.57%), Postives = 172/277 (62.09%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R+SD L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L EE A  FF Q++E ++ CH   VLHRDIKDENIL+D N   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI  CL   PS R    EI NHPW+Q
Sbjct:   18 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQ 291
[Close]
BLAST of pim-1 vs. UniProt/SwissProt
Match: sp|Q95LJ0|PIM1_FELCA (Serine/threonine-protein kinase pim-1 OS=Felis catus OX=9685 GN=PIM1 PE=2 SV=1)

HSP 1 Score: 244.973 bits (624), Expect = 6.333e-76
Identity = 128/277 (46.21%), Postives = 173/277 (62.45%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R++D L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L EE A  FF Q++E ++ CH   VLHRDIKDENIL+D N   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI  CL   PS R +  EI NHPW+Q
Sbjct:   18 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPSFEEIQNHPWMQ 291
[Close]
BLAST of pim-1 vs. UniProt/SwissProt
Match: sp|P06803|PIM1_MOUSE (Serine/threonine-protein kinase pim-1 OS=Mus musculus OX=10090 GN=Pim1 PE=1 SV=3)

HSP 1 Score: 244.588 bits (623), Expect = 1.014e-75
Identity = 129/286 (45.10%), Postives = 177/286 (61.89%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMAS 1110
            +DL+  +   G+E     S YQ    +G GGFG+V+ G R++D L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L E+ A  FF Q++E ++ CH   VLHRDIKDENIL+D +   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI+ CL   PS R +  EI NHPW+Q   L   AS
Sbjct:   18 NDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSDFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEDLARGFFWQVLEAVRHCHNCGVLHRDIKDENILIDLSRGEIKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIKGQVFFRQTVSSECQHLIKWCLSLRPSDRPSFEEIRNHPWMQGDLLPQAAS 300
[Close]
BLAST of pim-1 vs. UniProt/SwissProt
Match: sp|Q9N0P9|PIM1_BOVIN (Serine/threonine-protein kinase pim-1 OS=Bos taurus OX=9913 GN=PIM1 PE=2 SV=1)

HSP 1 Score: 244.202 bits (622), Expect = 1.311e-75
Identity = 128/276 (46.38%), Postives = 171/276 (61.96%), Query Frame = 1 
Query:  265 DLNKIEFFNGEEF--FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            DL+  +   G+E     S YQ    +G GGFG+V+ G R++D L V IK +   +I+D +        +P+EV LL K      GVI +L +++      + LI+ R     DLFD+I+    L EE A  FF Q++E ++ CH   VLHRDIKDENIL+D N   + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  VS++C+ LI  CL   PS R    EI NHPW+Q
Sbjct:   19 DLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVADNLPVAIKHVEKDRISD-WGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER--PDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHDCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIVRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQ 291
[Close]
BLAST of pim-1 vs. TrEMBL
Match: I1ZIH4 (Pim-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 441.425 bits (1134), Expect = 1.920e-150
Identity = 210/211 (99.53%), Postives = 210/211 (99.53%), Query Frame = 1 
Query:  835 PPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIDQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 1467
            PPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEI QLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ
Sbjct:   87 PPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIVQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 297

HSP 2 Score: 177.178 bits (448), Expect = 1.081e-47
Identity = 83/84 (98.81%), Postives = 84/84 (100.00%), Query Frame = 1 
Query:  271 NKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDM 522
            NKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVID+
Sbjct:    3 NKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDI 86
[Close]
BLAST of pim-1 vs. TrEMBL
Match: T1DBL3 (Pim-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 439.113 bits (1128), Expect = 3.965e-148
Identity = 217/379 (57.26%), Postives = 273/379 (72.03%), Query Frame = 1 
Query:  223 MNFDMEQYE----YDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYF-SKPRETPKFYISENEDED 1344
            MN + EQ E     + E  L+ I+FF GE+ FR+ YQC+EE+GQGGFG+V+K  R  D+ +V++KFISNKK T+ Y WK+ +L +PLEV LLA+C+ VKGVI +LAFY++    GWYL+MNR+ +F+DLFDYIS  KYLSEE AAFF +Q++ IL  CHQ  VLHRDIKDENILVD +T  +YLIDFGSGAF K DDY  +DGTRVYSPPEWI++H YNG KLE WSLG+LLFDMVCGDIPF+ D QIL+G L++RH VS  C+DLI  CL HDP  R+ L EI+ HPW+ K    P+   +L    Y    + S+          S  S  YSPAET+SSSSGD+S + +YSQ IP  F SK + TPKFYIS+ E++D
Sbjct:    1 MNCESEQSELRKKMEEEQRLSDIDFFCGEDTFRNDYQCYEEVGQGGFGSVYKAVRREDQKKVVVKFISNKKNTEKYYWKSHDLEVPLEVVLLAQCKHVKGVITLLAFYQTTQADGWYLVMNRVERFMDLFDYISCKKYLSEEIAAFFLQQLVTILIGCHQSGVLHRDIKDENILVDLDTHDIYLIDFGSGAFFKDDDYTQYDGTRVYSPPEWIRDHRYNGSKLESWSLGILLFDMVCGDIPFSNDQQILSGHLRFRHVVSGQCKDLIHSCLTHDPCDRVTLFEIARHPWILKQG-QPLNKQSLVCTEYT-HLVRSH----------SQDSCEYSPAETVSSSSGDDSAEYQYSQVIPPCFSSKAKGTPKFYISDTEEDD 367
[Close]
BLAST of pim-1 vs. TrEMBL
Match: T1D128 (Pim-3 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1)

HSP 1 Score: 279.641 bits (714), Expect = 6.685e-86
Identity = 152/343 (44.31%), Postives = 214/343 (62.39%), Query Frame = 1 
Query:  256 VEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPW-VQKHHL--------NPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVD 1257
            +  D+ KI      E F + Y+C + IG+GGFG V    +LSD+ +V IKF+S+KKIT  Y  + +   IP+E++L+ +CR V GVI ++ +++    KGWY+IM R  +FVDLFDYI+   +L E+ A  F  Q++ I+K CH+  V HRDIKDENI+++ +T  +YLIDFG+G F     Y++FDGTRVYSPPEWI+   Y    LEVWSLG+LL+DMVCG++PF+ D+ I+NG   YR  V+  C+DLI+KCL++DP  RIN+ EI +HPW  Q  H+        NP     L++  + LS     P +  +    S   SL +   T   SSG E  D
Sbjct:    7 LSQDIEKIPHSESFEEFEAEYKCLQVIGEGGFGKVRSAIQLSDQRDVAIKFVSDKKITSWYYCQNQQKYIPMEISLMCRCREVAGVIKIIKYFQIKEHKGWYIIMERFERFVDLFDYITNQNHLKEKLAVDFMAQLMTIVKDCHRLGVCHRDIKDENIVINLDTMKIYLIDFGAGGFFHGGIYKDFDGTRVYSPPEWIQFKEYKVSSLEVWSLGILLYDMVCGNLPFDNDESIVNGIFHYRRPVTPSCQDLIQKCLQYDPCKRINMTEIIHHPWFTQYSHMNTIERVKRNPHLPCQLSSNLHNLS-----PASTTTSEDNSRRISLETSPFTTPQSSGLEDSD 344
[Close]
BLAST of pim-1 vs. TrEMBL
Match: A0A267FCC9 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027017g1 PE=3 SV=1)

HSP 1 Score: 279.641 bits (714), Expect = 1.642e-85
Identity = 134/262 (51.15%), Postives = 178/262 (67.94%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWK--AKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPW 1077
            E FR  YQ  +E+G GGFG VF+G R+ D LE  +K I   K++  + W        +P+E+ LL KC+ ++G++  +A+Y  +G   W ++M +I K +DLFDYIS  K+L+E +A  F +Q++E L  CH+  +LHRDIKDEN+LV+     ++LIDFGSGAFLK  DY +FDGTRVYSPPEWI+ H YNG K EVWSLG+LLFDMVCGDIPF  DDQI N +  +R  VS  CRDLI  CL+ D + R  + +I  HPW
Sbjct:   39 EEFRRDYQLGKELGSGGFGKVFEGLRVRDNLETAVKVIQKDKMSQ-FCWHRLPNGQKLPVEIVLLQKCQHIRGIVQPIAYY--EGPNEWVIVMKKIKKCMDLFDYISNKKFLAEVEAKSFMKQLLETLLACHEAGILHRDIKDENLLVNLCDGSIHLIDFGSGAFLKDTDYTDFDGTRVYSPPEWIRWHRYNGKKAEVWSLGILLFDMVCGDIPFERDDQICNSEPYFRRYVSPACRDLIMSCLQLDAARRPTIEQILRHPW 297
[Close]
BLAST of pim-1 vs. TrEMBL
Match: A0A267F9N8 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig027017g2 PE=3 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 1.990e-84
Identity = 132/262 (50.38%), Postives = 178/262 (67.94%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWK--AKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPW 1077
            E FR  Y+  +E+G GGFG VF+G R+ D LE  +K I   K++  + W        +P+E+ LL KC+ ++G++  +A+Y  +G   W ++M +I K +DLFDYIS  ++L+E +A  F +Q++E L  CH+  +LHRDIKDEN+LV+     ++LIDFGSGAFLK  DY +FDGTRVYSPPEWI+ H YNG K EVWSLG+LLFDMVCGDIPF  DDQI N +  +R  VS  CRDLI  CL+ D + R  + +I  HPW
Sbjct:   39 EEFRRDYRLGKELGSGGFGKVFEGLRVRDNLETAVKVIQKDKMSQ-FCWHRLPNGQKLPVEIVLLQKCQHIRGIVQPIAYY--EGPNEWVIVMKKIKKCMDLFDYISNKQFLAEVEAKSFMKQLLETLLACHEAGILHRDIKDENLLVNLCDGSIHLIDFGSGAFLKDTDYTDFDGTRVYSPPEWIRWHRYNGKKAEVWSLGILLFDMVCGDIPFERDDQICNSEPYFRRYVSPACRDLIMSCLQLDAARRPTIEQILRHPW 297
[Close]
BLAST of pim-1 vs. Ensembl Cavefish
Match: PIM3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:103043334])

HSP 1 Score: 254.988 bits (650), Expect = 7.700e-81
Identity = 127/269 (47.21%), Postives = 176/269 (65.43%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKN-LAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            E F   YQ    +G GGFGTV+ G+R+SD L V +K ++  ++T+   W + N + +PLE+ LL K     +GVI +L +Y+     GW ++M R     DLFD+I+    L E  A  FFRQ++E ++ C+   V+HRDIKDEN+LVD  T  + LIDFGSGAFLK   Y +FDGTRVYSPPEWI+ H Y+G    +WSLGVLL+DMVCGDIPF  D++I+ G+L +R  +SA+C+ LI+ CL   PS R  L +I  HPW++   ++
Sbjct:   15 EPFEKVYQVGSVLGSGGFGTVYAGSRISDGLPVAVKHVAKDRVTE---WGSINGVMVPLEIVLLKKVGSSFRGVIKLLDWYER--PDGWLIVMERPELVKDLFDFITEKGALDEATARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGDLKLIDFGSGAFLKDTVYTDFDGTRVYSPPEWIRFHRYHGRSATIWSLGVLLYDMVCGDIPFEQDEEIIRGRLYFRRRISAECQQLIKWCLSLRPSDRPTLEQIFEHPWMRPAEVS 278
[Close]
BLAST of pim-1 vs. Ensembl Cavefish
Match: PIM3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:103043334])

HSP 1 Score: 254.603 bits (649), Expect = 2.050e-80
Identity = 127/264 (48.11%), Postives = 174/264 (65.91%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKN-LAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            E F   YQ    +G GGFGTV+ G+R+SD L V +K ++  ++T+   W + N + +PLE+ LL K     +GVI +L +Y+     GW ++M R     DLFD+I+    L E  A  FFRQ++E ++ C+   V+HRDIKDEN+LVD  T  + LIDFGSGAFLK   Y +FDGTRVYSPPEWI+ H Y+G    +WSLGVLL+DMVCGDIPF  D++I+ G+L +R  +SA+C+ LI+ CL   PS R  L +I  HPW++
Sbjct:   35 EPFEKVYQVGSVLGSGGFGTVYAGSRISDGLPVAVKHVAKDRVTE---WGSINGVMVPLEIVLLKKVGSSFRGVIKLLDWYER--PDGWLIVMERPELVKDLFDFITEKGALDEATARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGDLKLIDFGSGAFLKDTVYTDFDGTRVYSPPEWIRFHRYHGRSATIWSLGVLLYDMVCGDIPFEQDEEIIRGRLYFRRRISAECQQLIKWCLSLRPSDRPTLEQIFEHPWMR 293
[Close]
BLAST of pim-1 vs. Ensembl Cavefish
Match: pim1 (serine/threonine-protein kinase pim-1-like [Source:NCBI gene;Acc:103031835])

HSP 1 Score: 249.98 bits (637), Expect = 1.458e-78
Identity = 121/269 (44.98%), Postives = 170/269 (63.20%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            +E F   YQ    +G GGFGTV+ G R++D   V IK ++  ++T+  +       +P+E+ LL K     +GVI ML +Y+      + ++M R     DLFD+I+    L EE A  FFRQ++E ++ CH   V+HRDIKDENIL+D  +  + LIDFGSGA LK   Y +FDGTRVYSPPEWIK H Y+G    VWSLG+LL+DMVCGDIPF  D++I+ G++ +R  +S +C+ LI+ CL   P+ R +  ++ NHPW+Q    N
Sbjct:   29 KEPFEKVYQVGSVLGSGGFGTVYAGLRIADGAPVAIKHVAKDRVTEWGELPITGARVPMEIVLLKKVSTGFRGVIKMLDWYER--PDSFIIVMERPENAKDLFDFITEKGALPEELARSFFRQVLEAVRHCHNSGVVHRDIKDENILIDLRSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIKYHRYHGRSATVWSLGILLYDMVCGDIPFEQDEEIVRGQVLFRRRISTECQQLIKWCLALRPADRPSFEDLVNHPWMQSSSTN 295
[Close]
BLAST of pim-1 vs. Ensembl Cavefish
Match: pim3 (serine/threonine-protein kinase pim-3-like [Source:NCBI gene;Acc:103024220])

HSP 1 Score: 248.44 bits (633), Expect = 5.723e-78
Identity = 132/289 (45.67%), Postives = 180/289 (62.28%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLA-IPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSN 1158
            E F   YQ    +G GGFGTV+ G+RL+D L V IK ++ +++T+   W + N + +PLEV LL K     +GVI ++ +Y+     GW ++M R     DLFDYI+    L E+ A  FFRQ++E ++ C+   V+HRDIKDEN+LVD  T  + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLGVLL+DMVCGDIPF  D++I+ G L +R  +S DC+ LI+ CL   PS R  L +I  H W     ++    +   T +  L  IN++
Sbjct:   35 EPFEKIYQVGSVLGSGGFGTVYAGSRLADGLPVAIKHVAKERVTE---WGSVNGSLVPLEVLLLKKVGNSFRGVIKLIDWYER--PDGWLIVMERPEMVKDLFDYITEKGALDEDTARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGDLKLIDFGSGAVLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVCGDIPFEHDEEIMKGSLFFRRRISPDCQQLIKWCLCLRPSDRPTLEQIFEHQW-----MHTKKDSKAETGDITLHVINTD 313
[Close]
BLAST of pim-1 vs. Ensembl Cavefish
Match: pim2 (Pim-2 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:58054])

HSP 1 Score: 219.935 bits (559), Expect = 3.021e-67
Identity = 116/281 (41.28%), Postives = 164/281 (58.36%), Query Frame = 1 
Query:  262 DDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKF-ISNKKITDTYKWKAKNLAIPLEVALLAKC---RPV----KGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            DD+  +     +E F   Y+C   +G GGFG+VF G R+SD L+V  K   S+  ++       K   +P+E+ALL +     P     +G+I ML +++  G+ G+ ++  R     DLFD+I+    + E  A  F +Q++E ++ CH + V+HRDIKDENILVD  T  + +IDFGSGA LK   Y +F+GTRVYSPPEWI +  Y    L VWSLGVLL+DMVCGDIPF  D  I++    +   +S +C+ LI  CL      R  L +I  HPW+
Sbjct:   12 DDVEDVRGKTAKEPFEKQYKCGALLGSGGFGSVFAGQRISDGLQVNSKTSFSHHFLSLCPSQPDKPSLVPMEIALLLQLGRESPAGPSHRGIIRMLDWFEVPGQ-GYLIVFERPQPCKDLFDFITERGVVEEPLAQRFLKQVVEAIQFCHSKGVVHRDIKDENILVDTRTGDLKIIDFGSGALLKDSIYTDFEGTRVYSPPEWIVHQQYEAVPLTVWSLGVLLYDMVCGDIPFEMDRDIVSANPSFTKRISKECQSLIRWCLSFHSKDRPTLEQILQHPWM 291
[Close]
BLAST of pim-1 vs. Ensembl Sea Lamprey
Match: snrka (SNF related kinase a [Source:ZFIN;Acc:ZDB-GENE-040718-84])

HSP 1 Score: 125.561 bits (314), Expect = 5.622e-31
Identity = 90/300 (30.00%), Postives = 141/300 (47.00%), Query Frame = 1 
Query:  316 YQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALL----AKCRPVKGVIDMLAFYKS-DGKKGWYLIMNRIAKFVDLFDYISRAKY-LSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFN------TDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANY-PLSYINSNPIAQR 1173
            Y   + +G+G F  V     +    +V +K I   K+             P+  + L     +C  +    +++  Y+  D +   YLI+  +A   DL+DYI R +  L EE A  +F Q++  +  CH+  V+HRD+K EN++  E    V L DFG S  F          G+  YS PE +    Y+   +++WSLGV+L+ +VCG  PF       T   I++ K      +S +C+DLI + L+ DP  R +L E+  HPW+     +P A  +    +Y  LS    N I QR
Sbjct:   16 YDLEKTLGRGHFAVVKLARHVFTGEKVAVKVIDKSKLD------------PMATSHLFQQEVRCMKLVQHPNVVRLYEVIDTQTKLYLILE-LADGGDLYDYIMRHEGGLQEELAKTYFAQVVHAISYCHRLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNLFQPGTKLATSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILYMLVCGHPPFQEANDSETLTMIMDCKYTVPAHISRECKDLIARMLQRDPRRRASLQEMEGHPWLCGVDPSPAAKCSTPLISYKSLSEDEHNGIVQR 302
[Close]
BLAST of pim-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006410.1 (pep scaffold:Pmarinus_7.0:GL476370:17405:31068:-1 gene:ENSPMAG00000005688.1 transcript:ENSPMAT00000006410.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.176 bits (313), Expect = 9.645e-31
Identity = 82/275 (29.82%), Postives = 143/275 (52.00%), Query Frame = 1 
Query:  292 GEEFFR-SHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHH 1092
            GEE     +Y+  + IG+G F  V     +    EV IK I   ++  T   K     +  EV ++ KC     ++ +    +++  K  YL+M   A   ++FDY+     + E++A   FRQI+  ++ CHQ+ ++HRD+K EN+L+D +   + + DFG S  F   +    F G+  Y+ PE  +   Y+G +++VWSLGV+L+ +V G +PF+        +++L GK +    +S DC +L+++ L  +P  R +L +I    W+   H
Sbjct:   30 GEELPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQK-----LFREVRIM-KCLNHPNIVKLYEVIETE--KTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKNIVHRDLKAENLLLDVDM-HIKIADFGFSNEFTLVNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELREKVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGSLEQIMRDRWMNVGH 294
[Close]
BLAST of pim-1 vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897])

HSP 1 Score: 120.168 bits (300), Expect = 4.899e-29
Identity = 83/299 (27.76%), Postives = 144/299 (48.16%), Query Frame = 1 
Query:  271 NKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVK-----GVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHH----LNPMASTTL 1119
            N I     E      Y+  + IG+G F  V          EV +K I   ++  +   K           L  + R +K      ++ +    +++  K  YL+M   A   ++FDY+     + E++A   FRQI+  ++ CHQ+ ++HRD+K EN+L+D + + + + DFG S  F        F G+  Y+ PE  +   Y+G +++VWSLGV+L+ +V G +PF+        +++L GK +    +S DC +L+++ L  +P+ R +L +I    W+   H    L P    TL
Sbjct:   39 NSITVAEVEHAHIGTYRLLKTIGKGNFAKVKLARHTLTGREVAVKIIDKTQLNPSSLQK-----------LFREVRIMKILNHPNIVKLFEVIETE--KTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMN-IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPAKRGSLEQIMKDRWMNVGHEEDELKPYVEPTL 322
[Close]
BLAST of pim-1 vs. Ensembl Sea Lamprey
Match: MARK3 (microtubule affinity regulating kinase 3 [Source:HGNC Symbol;Acc:HGNC:6897])

HSP 1 Score: 115.546 bits (288), Expect = 3.636e-28
Identity = 77/275 (28.00%), Postives = 137/275 (49.82%), Query Frame = 1 
Query:  289 NGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHH 1092
            +G+     +Y+  + IG+G F  V          EV +K I   ++  +   K       ++V        +  VI+M        +K  YL+M   +   ++FDY+     + E++A   FRQI+  ++ CHQ+ ++HRD+K EN+L+D + + + + DFG S  F        F G+  Y+ PE  +   Y+G +++VWSLGV+L+ +V G +PF+        +++L GK +    +S DC +L+++ L   P  R +L +I    W+   H
Sbjct:   59 SGQTQRVGNYRLLKTIGKGNFAKVKLAKHTLTGQEVAVKIIDKTQLNTSSLQKLFREVRIMKVLNHPNIVKLFEVIEM--------EKTLYLVME-YSSGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIVHRDLKAENLLLDADMN-IKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLHPLKRGSLEQIMKDRWMNVKH 323
[Close]
BLAST of pim-1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008748.1 (pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 gene:ENSPMAG00000007907.1 transcript:ENSPMAT00000008748.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 110.923 bits (276), Expect = 4.953e-27
Identity = 79/273 (28.94%), Postives = 137/273 (50.18%), Query Frame = 1 
Query:  304 FRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTD--FVYLIDFGSGAFLKTDD--YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD------QILNGKLKYRH----CVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            F   YQ +EE+G+G F  V +  ++S   E   K I+ KK++     K +  A          CR +K   +++  ++S  ++G++ ++  +    +LF+ I   +Y SE  A+   +QI+E +  CHQ  ++HRD+K EN+L+        V L DFG    ++ D   +  F GT  Y  PE ++   Y G  +++W+ GV+L+ ++ G  PF  +D      QI  G   +       V+A+ ++LI + L  +P+ RI   E   HPW+
Sbjct:   10 FTDEYQLYEELGKGAFSVVRRCVKVSTGQEFAAKIINTKKLSARDHQKLEREA--------RICRLLKHS-NIVRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPY-GKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTAEAKNLINQMLTINPAKRITAAEALKHPWI 272
[Close]
BLAST of pim-1 vs. Ensembl Yeast
Match: PSK1 (PAS domain-containing serine/threonine protein kinase; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status; PSK1 has a paralog, PSK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000015])

HSP 1 Score: 146.747 bits (369), Expect = 8.255e-38
Identity = 87/265 (32.83%), Postives = 149/265 (56.23%), Query Frame = 1 
Query:  310 SHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKI-TDTYKWKAKNLAIPLEVALLAKC--RPVKGVIDMLAFYKSDGKKGWYLIMNRI---AKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHC--VSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            S +   +++G+G +G V       +R  V+IK I  ++I  DT+    K   IP E+ ++A    +P + ++ +L F++ D    +Y I   +      +DLFD I     ++E +A   F+Q++  +K  H Q ++HRDIKDEN++VD +  FV +IDFGS A++K+  +  F GT  Y+ PE +  + Y G   ++W++G+LL+ +V  + PF   D+IL G LK+ +   VS DC +LI+  L      R  +++I+N  W+
Sbjct: 1094 SDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFEDDD---YYYIETPVHGETGCIDLFDLIEFKTNMTEFEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVD-SKGFVKIIDFGSAAYVKSGPFDVFVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNAEEVSEDCIELIKSILNRCVPKRPTIDDINNDKWL 1354
[Close]
BLAST of pim-1 vs. Ensembl Yeast
Match: PSK2 (PAS-domain containing serine/threonine protein kinase; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation); PSK2 has a paralog, PSK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005405])

HSP 1 Score: 139.813 bits (351), Expect = 1.742e-35
Identity = 85/266 (31.95%), Postives = 144/266 (54.14%), Query Frame = 1 
Query:  310 SHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKI-TDTYKWKAKNLAIPLEVALLAKCR--PVKGVIDMLAFYKSDGKKGWYLIMNRI---AKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHC--VSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            S +   + +G+G +G V       +   V+IK I  ++I  DT+    K   IP E+ ++A       + ++ +L F++ D    +Y I   +      +DLFD I   K + E +A   F+Q++  +K  H Q ++HRDIKDEN++VD +  FV LIDFGS A++K+  +  F GT  Y+ PE +    Y G   ++W+LGVLL+ ++  + P+   D+IL G+L++     VS +C  LI++ L  +   R  ++EI    W++
Sbjct:  839 SDFTILQVMGEGAYGKVNLCIHNREHYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKNSQENILKLLDFFEDDD---YYYIETPVHGETGSIDLFDVIEFKKDMVEHEAKLVFKQVVASIKHLHDQGIVHRDIKDENVIVDSH-GFVKLIDFGSAAYIKSGPFDVFVGTMDYAAPEVLGGSSYKGKPQDIWALGVLLYTIIYKENPYYNIDEILEGELRFDKSEHVSEECISLIKRILTREVDKRPTIDEIYEDKWLK 1100
[Close]
BLAST of pim-1 vs. Ensembl Yeast
Match: HSL1 (Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584])

HSP 1 Score: 120.939 bits (302), Expect = 3.230e-29
Identity = 68/200 (34.00%), Postives = 108/200 (54.00%), Query Frame = 1 
Query:  520 MLAFYKSDGKKGWYLIMNRIAKFVD---LFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAF-LKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD------QILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKH 1089
            M  F   + K   YL++    ++VD   LFDY+     L E +A  +F+QI+E +  CH   + HRD+K EN+L+D+    + + DFG  A  L     +   G+  Y+ PE +    Y+G   +VWS G++LF ++ G +PFN D+      ++ +GK +    +S++ RDLI K L  DP  RI   EI  HP ++K+
Sbjct:  177 MALFEVWENKSELYLVL----EYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPSNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKY 372
[Close]
BLAST of pim-1 vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885])

HSP 1 Score: 115.931 bits (289), Expect = 6.538e-28
Identity = 86/267 (32.21%), Postives = 137/267 (51.31%), Query Frame = 1 
Query:  313 HYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG------SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD------QILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPW 1077
            +YQ  + +G+G FG V      +   +V +K I NKK+      + +   I  E++ L   R    +I +    KS  +    +IM       +LFDYI +   +SE++A  FF+QII  ++ CH+ K++HRD+K EN+L+DE+ + V + DFG       G FLKT       G+  Y+ PE I    Y G +++VWS GV+L+ M+C  +PF+ +        I NG       +S     LI++ L  +P  RI+++EI    W
Sbjct:   54 NYQIVKTLGEGSFGKVKLAYHTTTGQKVALKII-NKKVLAKSDMQGR---IEREISYLRLLRH-PHIIKLYDVIKSKDE----IIMVIEYAGNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLLDEHLN-VKIADFGLSNIMTDGNFLKTS-----CGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPKFLSPGAAGLIKRMLIVNPLNRISIHEIMQDDW 305
[Close]
BLAST of pim-1 vs. Ensembl Yeast
Match: YPL150W_mRNA (Protein kinase of unknown cellular role; binds phosphatidylinositols and cardiolipin in a large-scale study [Source:SGD;Acc:S000006071])

HSP 1 Score: 105.531 bits (262), Expect = 2.021e-24
Identity = 59/172 (34.30%), Postives = 97/172 (56.40%), Query Frame = 1 
Query:  592 DLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQ------ILNGKLKY-RHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQ 1083
            +L+D++   + +S  +    F QI   +   H    +HRD+K ENIL+D+N +   L DFG +   +         GT VY  PE I+   Y+GFK+++WSLGV+L+ ++ G +PF+ DD+      I+N + KY    +  D RDLI + L  +P  R +L+++  HP++Q
Sbjct:  118 ELYDHLLSLRRISLLECGELFAQISGAVYYAHSMHCVHRDLKLENILLDKNGN-AKLTDFGFTRECMTKTTLETVCGTTVYMAPELIERRTYDGFKIDIWSLGVILYTLITGYLPFDDDDEAKTKWKIVNEEPKYDAKVIPDDARDLISRLLAKNPGERPSLSQVLRHPFLQ 288
[Close]
BLAST of pim-1 vs. Ensembl Nematostella
Match: EDO46861 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNH5])

HSP 1 Score: 176.407 bits (446), Expect = 2.057e-51
Identity = 90/241 (37.34%), Postives = 138/241 (57.26%), Query Frame = 1 
Query:  358 VFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            V+ GTR+ D   V IK I    +   +  +   +++P+EV  L +      V+ +  +++ +  + + L++ R   + DLFDYI+  K LSE +A   F+Q++  +  C  + V HRDIKDEN+L+D  T  V L DFGSG  L+   Y +++GTR Y PPEW + H Y+     VWSLG+LLF+M+ GD+PF    +I+ G+L +   VS + + L+   L   PSYR  L  I  HPW+
Sbjct:    2 VYAGTRVRDGKPVAIKVIPKNNVY--FFEEVGGISVPMEV-YLHRVLDHPNVVRLYDYFEYN--QAYVLVLERPTHYRDLFDYITEKKLLSEREAKDIFKQVVHAVAYCEGKGVFHRDIKDENLLLDTKTGQVKLFDFGSGTVLENTLYTDYEGTRAYCPPEWFRFHRYHARPCTVWSLGILLFNMLSGDVPFANQIEIVRGELNFAENVSKEAQSLVRWLLAKHPSYRPTLENILKHPWL 237
[Close]
BLAST of pim-1 vs. Ensembl Nematostella
Match: EDO36587 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI81])

HSP 1 Score: 133.65 bits (335), Expect = 5.525e-35
Identity = 92/295 (31.19%), Postives = 144/295 (48.81%), Query Frame = 1 
Query:  292 GEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGV--IDMLAFYKS-DGKKGWYLIMNRIAKFVDLFDYI-SRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFN------TDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLS 1143
            G+      Y   E +G+G F  V     +     V +K I   K+ +  +             LL + R +K V   +++  Y+  D     YLI+  +    D++DYI +  K L EEKA +FFRQI+  +  CH+  V+HRD+K EN++  +N D   L DFG S  F+  +      G+  YS PE +    Y    ++VWSLGV+L+ +VCG  PF+      T  +I++ +      VS  C++LI + L  +P  R +L EI +HPW+Q+     + S     A  PL+
Sbjct:   11 GDSQIAGMYDLGETLGRGHFAVVKVARHVITGERVAVKVIDKTKLDEVSREH-----------LLKEVRCMKLVQHPNVVRLYQVIDTNTKLYLIL-ELGDGGDMYDYIMNHDKGLPEEKARYFFRQIVLAIDYCHKLHVVHRDLKPENVIFFKNQDMAKLTDFGFSNNFIPNEKLDTACGSLAYSAPEVLLGDAYEAPAVDVWSLGVILYMLVCGQAPFSEANDSETLTKIMDCRYDVPDHVSPLCKNLISRMLIREPHNRASLGEIMSHPWLQQGPTPLVPSDVPLVAELPLT 293
[Close]
BLAST of pim-1 vs. Ensembl Nematostella
Match: EDO47961 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKT6])

HSP 1 Score: 127.487 bits (319), Expect = 1.636e-33
Identity = 83/263 (31.56%), Postives = 135/263 (51.33%), Query Frame = 1 
Query:  316 YQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFL-KTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD--QILN---GKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQK 1086
            Y     +G+G F  V           V IK I  +K    Y +K     +P E+ ++ K      VI +    +++ K   YLI+  +A+  DL +YI++   L EE+A   F Q +  +  CH+++V+HRD+K EN+L+D N   + + DFG      KT+  + F G+  Y  PE ++   Y+G   ++WS+GV+L+ +VC  +PF  DD   I+N    KL++    S +CR+LI K L  D   R    E+ + PW ++
Sbjct:    8 YTVMRNLGEGAFAKVKLAKSKKHNCHVAIKIIDKRKAPKDYIYKF----LPREIRVMHKLNH-PNVIQLYEAIETETK--VYLILE-LAEGGDLLEYINKNALLPEERARVIFCQFVATMAYCHKERVVHRDLKCENLLLDANGR-LKITDFGFACNTHKTNILQTFCGSYAYCSPEILRGDLYDGQASDIWSMGVVLYALVCARLPFGDDDLRAIMNREPRKLRFSKKTSKECRELIRKMLALDEKKRPTAEELLHEPWCKE 261
[Close]
BLAST of pim-1 vs. Ensembl Nematostella
Match: EDO37143 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGS0])

HSP 1 Score: 122.865 bits (307), Expect = 1.700e-31
Identity = 87/260 (33.46%), Postives = 140/260 (53.85%), Query Frame = 1 
Query:  334 IGQGGFGTV--FKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDD------QILNGK--LKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            +G+G +  V     T+L++   V +K I  K+    +     N  +P E+ ++ + R  K +I +L  ++   ++  Y+IM  +A   DL +YI     + E KA   F Q+++ +K CHQQ V+HRD+K EN+L+D   D V L DFG S    + +  + F G+  Y+  E ++   Y+G K ++WSLG++L+ MV G +PF+  +      QI  G    K +  VS +CRDLI   L H+  YRI + EI  H W+
Sbjct:   24 LGEGTYAKVKCAYSTQLAN--HVAVKIIDKKRAPSDFI----NKFLPREMVVIKRLRH-KHIIQVLDLFEV--REKVYVIME-LATRGDLLEYIRYRGCVRERKAKKVFSQLLQAVKYCHQQGVIHRDLKCENVLLDIG-DNVKLTDFGFSKLNPRKELCKTFCGSAAYAAIEILQGTEYDGEKADIWSLGIILYTMVTGRMPFDDANMTTLLRQIKRGVEFRKPKQMVSEECRDLIRCMLTHNYEYRITIPEIEAHRWI 272
[Close]
BLAST of pim-1 vs. Ensembl Nematostella
Match: EDO30768 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZV3])

HSP 1 Score: 124.405 bits (311), Expect = 2.658e-30
Identity = 81/276 (29.35%), Postives = 138/276 (50.00%), Query Frame = 1 
Query:  289 NGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVK-----GVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFG-SGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTD------DQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            N EE     Y+  + IG+G F  V     +    EV IK I   ++  +   K           L  + R +K      ++ +    ++D  K  YL+M   A   ++FDY+     + E++A   FRQI+  ++ CHQ+ V+HRD+K EN+L+D + + + + DFG S  F   +    F G+  Y+ PE  +   Y+G +++VWSLGV+L+ +V G +PF+        +++L GK +    +S DC +L++K L  +P  R  L +     W+
Sbjct:   29 NSEEVHIGRYRLIKTIGKGNFAKVKLAKHVPTGKEVAIKIIDKTQLNPSSLQK-----------LFREVRIMKFLDHPNIVKLYEVIETD--KTLYLVME-YASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHVIHRDLKAENLLLDADMN-IKIADFGFSNEFTPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLVLNPQKRARLEQTMTDKWM 289
[Close]
BLAST of pim-1 vs. Ensembl Medaka
Match: pim3 (Pim-3 proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:101171374])

HSP 1 Score: 254.988 bits (650), Expect = 1.600e-80
Identity = 130/290 (44.83%), Postives = 182/290 (62.76%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKN-LAIPLEVALLAKCRP-VKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSN 1158
            +E F   YQ    +G GGFGTV+ G R+SD   V +K ++ +++T+   W + N + +PLE+ LL K     +GVI +L +Y+     GW ++M R     DLFD+I+    L E  A  FFRQ++E ++ C+   V+HRDIKDEN+LVD  T  + LIDFGSGA LK   Y +FDGTRVYSPPEWI+ H Y+G    VWSLGVLL+DMVCGDIPF  D++IL GK+ +R  VS +C+ +I+ CL   PS R  L++I +HPW++    +P +S         L  I ++
Sbjct:   33 KEPFERVYQVGSVLGSGGFGTVYAGNRISDGAPVAVKHVAKERVTE---WGSINGVMVPLEILLLKKVSSSFRGVIKLLDYYER--PDGWLIVMERPDLVKDLFDFITEKGALDEGTARGFFRQVLEAVRHCYSCGVVHRDIKDENLLVDLRTGELKLIDFGSGAILKDTVYTDFDGTRVYSPPEWIRFHRYHGRSATVWSLGVLLYDMVCGDIPFEQDEEILRGKVYFRRRVSPECQQIIKWCLALRPSDRPTLDQICDHPWMRMASESPKSSEEPAAGEIRLRTIGTD 317
[Close]
BLAST of pim-1 vs. Ensembl Medaka
Match: pim1 (serine/threonine-protein kinase pim-1 [Source:NCBI gene;Acc:101157054])

HSP 1 Score: 245.743 bits (626), Expect = 5.138e-77
Identity = 128/308 (41.56%), Postives = 184/308 (59.74%), Query Frame = 1 
Query:  295 EEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKC-RPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSP 1215
            +E F   YQ    +G GGFGTV+ GTR+SD + V +K ++  ++++ +        +P+E+ LL K     +GVI ML +++      + ++M R     DLFD+I+    L EE A  FFRQ++E ++ CH   V+HRDIKDENIL+D  T  + LIDFGSGA LK   Y +FDGTRVYSPPEWIK H Y G    VWSLG+LL+DMVCGDIPF  D++I  G++ +R  +S +C+ LI+ CL   P+ R +  ++ NH W+Q       AS+ ++TA             +   H+IS   S ++P
Sbjct:   27 KEPFEKLYQVGAVLGSGGFGTVYAGTRISDGVPVAVKHVARDRVSE-WGELPSGARVPMEIVLLKKVGTGFRGVIKMLDWFER--PDSFIIVMERPENVKDLFDFITERGALPEELARSFFRQVLEAVRHCHSCGVVHRDIKDENILIDLRTGEMKLIDFGSGALLKDTIYTDFDGTRVYSPPEWIKYHRYQGRSATVWSLGILLYDMVCGDIPFEHDEEITRGQVLFRRRISTECQHLIKWCLSLRPTDRPSFEDVINHSWMQS-----TASSGVSTAQ------TEKTTTEIRLHSISHEPSSFTP 320
[Close]
BLAST of pim-1 vs. Ensembl Medaka
Match: ENSORLT00000032540.1 (serine/threonine-protein kinase pim-2-like [Source:NCBI gene;Acc:101156739])

HSP 1 Score: 215.312 bits (547), Expect = 4.101e-65
Identity = 112/267 (41.95%), Postives = 155/267 (58.05%), Query Frame = 1 
Query:  301 FFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVA---LLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKH 1089
            F   ++     +G+GGFG VF G R SDR+ V +KF+    +  T   +    + PLEV    ++ K  P  G+I ML FYK+ G   W ++        DLF YI+  K L E+ A  F  Q+I+ L  CH + V+H D+KDEN+L+D +T  + LIDFGS  FL+ D  Y  F GT VY+PPE +   CY     EVWSLG+LL+DMV GDIPF  D++IL G+L+++  +S DC  L++ CL   P  R  L +I  HPW+ K 
Sbjct:   17 FREKYWMSSHRLGKGGFGKVFLGKRRSDRISVALKFVP---LLRTRCCEVDGTSKPLEVVALEMVTKDPPFPGIIRMLDFYKTRG--AWVIVTETPENTQDLFHYITTCKRLCEDTARDFLGQVIQALLHCHSRGVVHMDVKDENLLLDPSTHKLLLIDFGSAVFLEPDKVYDTFHGTAVYAPPERLTQGCYKALPSEVWSLGILLYDMVHGDIPFQNDEEILLGELRFKKDLSEDCVALMQWCLSRAPEERPTLKDILAHPWMSKQ 278
[Close]
BLAST of pim-1 vs. Ensembl Medaka
Match: ENSORLT00000010626.2 (pep primary_assembly:ASM223467v1:12:12000679:12006348:1 gene:ENSORLG00000008461.2 transcript:ENSORLT00000010626.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 213.772 bits (543), Expect = 1.240e-64
Identity = 111/256 (43.36%), Postives = 152/256 (59.38%), Query Frame = 1 
Query:  334 IGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVA---LLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKH 1089
            +G+GGFG VF G R SDR+ V +KF+    +  T   +    + PLEV    ++ K  P  G+I ML FYK+ G   W ++        DLF YI+  K L E+ A  F  Q+I+ L  CH + V+H D+KDEN+L+D +T  + LIDFGS  FL+ D  Y  F GT VY+PPE +   CY     EVWSLG+LL+DMV GDIPF  D++IL G+L+++  +S DC  L++ CL   P  R  L +I  HPW+ K 
Sbjct:   54 LGKGGFGKVFLGKRRSDRISVALKFVP---LLRTRCCEVDGTSKPLEVVALEMVTKDPPFPGIIRMLDFYKTRG--AWVIVTETPENTQDLFHYITTCKRLCEDTARDFLGQVIQALLHCHSRGVVHMDVKDENLLLDPSTHKLLLIDFGSAVFLEPDKVYDTFHGTAVYAPPERLTQGCYKALPSEVWSLGILLYDMVHGDIPFQNDEEILLGELRFKKDLSEDCVALMQWCLSRAPEERPTLKDILAHPWMSKQ 304
[Close]
BLAST of pim-1 vs. Ensembl Medaka
Match: ENSORLT00000041570.1 (pep primary_assembly:ASM223467v1:10:18938984:18940525:-1 gene:ENSORLG00000023590.1 transcript:ENSORLT00000041570.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 197.593 bits (501), Expect = 1.519e-57
Identity = 106/256 (41.41%), Postives = 147/256 (57.42%), Query Frame = 1 
Query:  334 IGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVA---LLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDD-YRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKH 1089
            +G+GGFG VF G R SD + V +K I    ++ T   +    + P E     +++K  P  G+I ML FYK+     W ++  +     DL++YI+ +K L E+ A  F  Q+I+ L  CH + V+H D+KDEN+LVD  T  + LIDFGS  FL+ D  Y  F GT  Y PPE +   CY     EVWSLG+LL+DMV GDIPF  D ++L G+L++   +S DC  LI+ CL   P  R  L +I  HPW+ K 
Sbjct:   47 LGKGGFGKVFLGKRRSDGISVALKIIP---LSRTRCCEVDGTSKPFEAVALEMVSKDPPFPGIIRMLDFYKT--PYNWVIVTEKPENTQDLYEYITISKRLREDTAREFLGQVIQALLHCHSRGVVHMDVKDENLLVDLTTLELKLIDFGSAEFLEPDKVYDMFHGTAAYGPPERLTQGCYKALPSEVWSLGILLYDMVHGDIPFGNDRELLLGELRFEKDLSEDCVALIKWCLSRTPEERPMLKDILAHPWMLKR 297
[Close]
BLAST of pim-1 vs. Planmine SMEST
Match: SMESG000017137.1 (SMESG000017137.1)

HSP 1 Score: 862.448 bits (2227), Expect = 0.000e+0
Identity = 414/415 (99.76%), Postives = 414/415 (99.76%), Query Frame = 1 
Query:  223 MNFDMEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIDQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 1467
            MNFDMEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEI QLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ
Sbjct:    1 MNFDMEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIVQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 415
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BLAST of pim-1 vs. Planmine SMEST
Match: SMESG000017137.1 (SMESG000017137.1)

HSP 1 Score: 853.973 bits (2205), Expect = 0.000e+0
Identity = 410/411 (99.76%), Postives = 410/411 (99.76%), Query Frame = 1 
Query:  235 MEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIDQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 1467
            MEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEI QLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ
Sbjct:    1 MEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLTTANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQTIPEYFSKPRETPKFYISENEDEDSSEFPAPEIVQLKFSDNVRSHLENLNNEYLSFTQSCIVNPQ 411
[Close]
BLAST of pim-1 vs. Planmine SMEST
Match: SMESG000014593.1 (SMESG000014593.1)

HSP 1 Score: 267.7 bits (683), Expect = 1.411e-84
Identity = 127/260 (48.85%), Postives = 174/260 (66.92%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPW 1077
            E F+  YQ  E IG+GGFG V K  R SD+ +V IKFISN KIT  + +   N  +PLE+AL+ +CR V GVI +  ++     KGWY++M+R    +DLFD+I+    +SE+ A+ F  Q+I IL  CH   V HRDIKDENI++D +T+ +YLIDFG+G  L    Y  FDGTRVYSPPEWI+   Y+   LE+WSLG+LL+DMVCG++P++ DD I+N  L +R  +S  C+DLI+ CL+ +P  R +L+ I  H W
Sbjct:   18 EDFQYEYQSLEIIGEGGFGKVRKAIRRSDKKQVAIKFISNSKITSWHFYSKINKQVPLEIALMCRCRKVDGVIKIFKYFYIKEHKGWYIVMDRFENHIDLFDHITNMGQISEKDASNFMNQLITILINCHNLGVCHRDIKDENIIIDLSTNKIYLIDFGAGGILHDGLYSEFDGTRVYSPPEWIQYKRYHAVPLEIWSLGILLYDMVCGNLPYDNDDGIVNCCLAFRRPISHFCQDLIKNCLERNPENRPSLSNILKHRW 277
[Close]
BLAST of pim-1 vs. Planmine SMEST
Match: SMESG000072329.1 (SMESG000072329.1)

HSP 1 Score: 236.884 bits (603), Expect = 2.914e-72
Identity = 111/276 (40.22%), Postives = 171/276 (61.96%), Query Frame = 1 
Query:  253 DVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWV 1080
            D E+ L K  F  G+      Y   +E+G+G +G V  G R  D   V IK +    I + Y  K   + IP+E+ LL+    + GVI M+ +Y    +  WY++M R A+ +DLF+YI    +L+E  A+  F ++  I+ +CH + +LHRDIK+ENIL+D+ T  ++LIDFGSG  +  D++ +++GT  Y+PPEWIK   Y G +LE WSLG++L+ MVCG IPF  +++IL+  +K+   +S +C++LI KC++ DP  RI  +EI  HPW+
Sbjct:    4 DYENYLRKFPFQQGKTKLELKYNYDKELGKGSYGNVLSGFRKKDHFSVAIKVLPTNLIDNWYFSKTLKMNIPMEILLLSLASNIDGVISMIEYYNDLEQSEWYIVMERFAETIDLFNYICSEGFLTEHLASQIFYELTRIIIECHLRGILHRDIKEENILIDKYTKKIWLIDFGSGGLMNDDNHYSYNGTEEYAPPEWIKYGHYRGCQLESWSLGIVLYSMVCGRIPFEDNNEILSNTIKFPRKISNNCKELILKCIERDPKNRIQPSEILKHPWI 279
[Close]
BLAST of pim-1 vs. Planmine SMEST
Match: SMESG000027798.1 (SMESG000027798.1)

HSP 1 Score: 228.409 bits (581), Expect = 5.506e-71
Identity = 113/267 (42.32%), Postives = 170/267 (63.67%), Query Frame = 1 
Query:  298 EFFRSHYQCHEEIGQGGFGTVFKGTRLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDMLAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEILKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGTRVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLKYRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLN 1098
            ++ ++ Y  + +IG+GGFG VFK T++S+   V +KF++  KI++    +     IP+E  LLA+C+ + GVI +L   + +  + W ++M R   F+DLFDYI+R   +SEE A F   Q+I  L  CH+  V HRDIKDENIL+D +T  + LIDFGSG +    +Y +F+GT +YSPPEWIK+  Y   +LE WS+G LL++M+ GD PF  +++IL   +      SA+CRDLI  CL  D   R++L++I  H   QK+H++
Sbjct:   17 KYIQNKYAIYGKIGEGGFGKVFKSTKISNGKSVALKFVAKDKISEYCLHEETQQKIPMEAVLLAECQGIPGVIKLLEIVELEEFQVWCIVMERNPNFIDLFDYINRCSQISEETAVFILTQLIHTLIGCHKAGVAHRDIKDENILIDVDTKEIKLIDFGSGHYYHDGEYFDFNGTSIYSPPEWIKDKHYFVKELESWSIGALLYNMITGDGPFKNENEILLAPISIDS-ASAECRDLILSCLCRDRENRMDLDKILCHKLFQKYHMS 282
The following BLAST results are available for this feature:
BLAST of pim-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PIM16.649e-7746.57Pim-1 proto-oncogene, serine/threonine kinase [Sou... [more]
PIM24.184e-7546.42Pim-2 proto-oncogene, serine/threonine kinase [Sou... [more]
PIM39.691e-7246.62Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
PIM25.943e-4651.75Pim-2 proto-oncogene, serine/threonine kinase [Sou... [more]
NUAK21.070e-3234.69NUAK family kinase 2 [Source:HGNC Symbol;Acc:HGNC:... [more]
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BLAST of pim-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prk-24.129e-6639.04Serine/threonine-protein kinase prk-2 [Source:Uni... [more]
prk-24.129e-6639.04Serine/threonine-protein kinase prk-2 [Source:Uni... [more]
prk-18.739e-5337.02Pim (Mammalian oncogene) Related Kinase [Source:U... [more]
prk-12.232e-5237.02Pim (Mammalian oncogene) Related Kinase [Source:U... [more]
prk-14.641e-5237.02Pim (Mammalian oncogene) Related Kinase [Source:U... [more]
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BLAST of pim-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pask5.827e-4032.25gene:FBgn0034950 transcript:FBtr0072160[more]
sff6.631e-3331.73gene:FBgn0036544 transcript:FBtr0334071[more]
sff6.960e-3331.73gene:FBgn0036544 transcript:FBtr0089527[more]
sff7.018e-3331.73gene:FBgn0036544 transcript:FBtr0334070[more]
CG84851.660e-3232.75gene:FBgn0033915 transcript:FBtr0087572[more]
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BLAST of pim-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pim16.381e-7545.83Pim-1 proto-oncogene, serine/threonine kinase [Sou... [more]
pim33.451e-7446.37Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
pim22.030e-7142.31Pim-2 proto-oncogene, serine/threonine kinase [Sou... [more]
pimr542.866e-5338.02Pim proto-oncogene, serine/threonine kinase, relat... [more]
pimr499.735e-5337.64Pim proto-oncogene, serine/threonine kinase, relat... [more]
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BLAST of pim-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ncbp18.069e-8150.19nuclear cap binding protein subunit 1 [Source:Xenb... [more]
ncbp11.214e-8049.10nuclear cap binding protein subunit 1 [Source:Xenb... [more]
PIM31.541e-7646.47Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
PASK2.940e-3834.17PAS domain containing serine/threonine kinase [Sou... [more]
PASK4.015e-3834.17PAS domain containing serine/threonine kinase [Sou... [more]
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BLAST of pim-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pim11.450e-7645.10proviral integration site 1 [Source:MGI Symbol;Acc... [more]
Pim23.115e-7446.01proviral integration site 2 [Source:MGI Symbol;Acc... [more]
Pim23.785e-7446.01proviral integration site 2 [Source:MGI Symbol;Acc... [more]
Pim36.791e-7346.99proviral integration site 3 [Source:MGI Symbol;Acc... [more]
Pim13.777e-3940.59proviral integration site 1 [Source:MGI Symbol;Acc... [more]
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BLAST of pim-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P26794|PIM1_RAT2.869e-7646.69Serine/threonine-protein kinase pim-1 OS=Rattus no... [more]
sp|P11309|PIM1_HUMAN3.193e-7646.57Serine/threonine-protein kinase pim-1 OS=Homo sapi... [more]
sp|Q95LJ0|PIM1_FELCA6.333e-7646.21Serine/threonine-protein kinase pim-1 OS=Felis cat... [more]
sp|P06803|PIM1_MOUSE1.014e-7545.10Serine/threonine-protein kinase pim-1 OS=Mus muscu... [more]
sp|Q9N0P9|PIM1_BOVIN1.311e-7546.38Serine/threonine-protein kinase pim-1 OS=Bos tauru... [more]
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BLAST of pim-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
I1ZIH41.920e-15099.53Pim-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1[more]
T1DBL33.965e-14857.26Pim-1 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
T1D1286.685e-8644.31Pim-3 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1[more]
A0A267FCC91.642e-8551.15Protein kinase domain-containing protein OS=Macros... [more]
A0A267F9N81.990e-8450.38Protein kinase domain-containing protein OS=Macros... [more]
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BLAST of pim-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PIM37.700e-8147.21Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
PIM32.050e-8048.11Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
pim11.458e-7844.98serine/threonine-protein kinase pim-1-like [Source... [more]
pim35.723e-7845.67serine/threonine-protein kinase pim-3-like [Source... [more]
pim23.021e-6741.28Pim-2 proto-oncogene, serine/threonine kinase [Sou... [more]
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BLAST of pim-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
snrka5.622e-3130.00SNF related kinase a [Source:ZFIN;Acc:ZDB-GENE-040... [more]
ENSPMAT00000006410.19.645e-3129.82pep scaffold:Pmarinus_7.0:GL476370:17405:31068:-1 ... [more]
MARK34.899e-2927.76microtubule affinity regulating kinase 3 [Source:H... [more]
MARK33.636e-2828.00microtubule affinity regulating kinase 3 [Source:H... [more]
ENSPMAT00000008748.14.953e-2728.94pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 ge... [more]
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BLAST of pim-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
PSK18.255e-3832.83PAS domain-containing serine/threonine protein kin... [more]
PSK21.742e-3531.95PAS-domain containing serine/threonine protein kin... [more]
HSL13.230e-2934.00Nim1p-related protein kinase; septin-binding kinas... [more]
SNF16.538e-2832.21AMP-activated S/T protein kinase; forms a complex ... [more]
YPL150W_mRNA2.021e-2434.30Protein kinase of unknown cellular role; binds pho... [more]
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BLAST of pim-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO468612.057e-5137.34Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO365875.525e-3531.19Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO479611.636e-3331.56Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO371431.700e-3133.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO307682.658e-3029.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of pim-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
pim31.600e-8044.83Pim-3 proto-oncogene, serine/threonine kinase [Sou... [more]
pim15.138e-7741.56serine/threonine-protein kinase pim-1 [Source:NCBI... [more]
ENSORLT00000032540.14.101e-6541.95serine/threonine-protein kinase pim-2-like [Source... [more]
ENSORLT00000010626.21.240e-6443.36pep primary_assembly:ASM223467v1:12:12000679:12006... [more]
ENSORLT00000041570.11.519e-5741.41pep primary_assembly:ASM223467v1:10:18938984:18940... [more]
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BLAST of pim-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000017137.10.000e+099.76SMESG000017137.1[more]
SMESG000017137.10.000e+099.76SMESG000017137.1[more]
SMESG000014593.11.411e-8448.85SMESG000014593.1[more]
SMESG000072329.12.914e-7240.22SMESG000072329.1[more]
SMESG000027798.15.506e-7142.32SMESG000027798.1[more]
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Cross References
External references for this transcript
DatabaseAccession
SmedGD GBrowseSMED30025671
GenBankAFJ24828.1
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025671 ID=SMED30025671|Name=pim-1|organism=Schmidtea mediterranea sexual|type=transcript|length=1548bp
AGTAATCAGCTGTATCGGGGGTGTATTCGTCTCGTCATGTTGTGACCTGC
ATGCATTAGTCAGTGTGTGTTAGTGTGTCAACAGAGAATTGTAGAGCTGC
AATGCTGTCATTTGATTGGTCGGTTTAGATAGAATGAAAATTATATTTGG
TCAATTCAATTATTACTATTGCAGTTTTGAAAAAAATAATCATCGCGGAG
TTTTTTTTAAATTTTATGAAGAATGAATTTTGACATGGAACAGTATGAAT
ATGATGTTGAAGATGATTTAAACAAAATTGAATTTTTTAATGGCGAAGAA
TTTTTTCGATCTCATTATCAGTGTCACGAAGAAATTGGTCAAGGGGGTTT
CGGAACAGTTTTCAAAGGCACTCGGCTGTCAGACAGATTGGAAGTTATTA
TAAAATTCATTTCCAACAAAAAAATCACAGACACATACAAATGGAAGGCG
AAAAATCTGGCAATCCCTCTTGAAGTAGCTTTGTTAGCAAAATGTCGACC
TGTCAAAGGGGTCATTGACATGTTGGCCTTCTACAAATCAGACGGGAAAA
AAGGCTGGTATTTGATAATGAATCGCATTGCAAAATTTGTCGACTTGTTC
GATTATATAAGCCGAGCGAAATATCTTTCAGAAGAGAAAGCCGCTTTCTT
TTTTCGACAAATTATCGAAATTCTCAAACAATGCCACCAACAGAAAGTGC
TTCATCGAGACATTAAGGATGAAAATATTCTCGTTGATGAAAACACAGAC
TTTGTTTATTTAATCGATTTCGGTTCCGGCGCATTTTTGAAAACAGATGA
CTACCGAAATTTTGATGGTACGAGAGTTTACAGTCCGCCGGAATGGATCA
AAAATCATTGCTACAATGGATTTAAATTGGAAGTTTGGTCTTTGGGGGTT
TTGCTATTCGACATGGTCTGTGGTGATATTCCTTTTAATACTGACGATCA
AATACTCAATGGGAAATTAAAATATCGGCATTGCGTCAGTGCAGACTGCC
GGGATTTGATAGAAAAATGTCTCAAACACGATCCATCTTATCGAATAAAC
TTAAATGAGATTTCCAATCATCCTTGGGTACAAAAGCATCATTTAAATCC
GATGGCATCGACGACGCTGACAACAGCAAATTATCCACTAAGTTATATCA
ATTCAAATCCGATTGCTCAACGCTCCTATCATGCGATTTCAGGCTCTTCC
TCACTCTATTCACCAGCCGAAACCATATCTTCCTCATCGGGAGACGAATC
TGTCGATGAGAAATATAGTCAAACCATTCCAGAGTACTTTTCCAAACCCC
GTGAAACTCCAAAATTTTATATATCAGAAAACGAAGACGAAGATTCCAGT
GAATTTCCGGCACCGGAAATCGATCAACTCAAATTTTCAGACAACGTCAG
ATCTCATTTAGAAAACCTAAACAACGAATACCTTTCTTTTACTCAATCTT
GTATAGTAAATCCTCAATAATATTTTTTCCTTTTTTTTGTACAAAAATGA
TTGATAAATGTTAATATTAAAAAATAAATATTTGATTTTTAAAAAAAA
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protein sequence of SMED30025671-orf-1

>SMED30025671-orf-1 ID=SMED30025671-orf-1|Name=SMED30025671-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=416bp
MNFDMEQYEYDVEDDLNKIEFFNGEEFFRSHYQCHEEIGQGGFGTVFKGT
RLSDRLEVIIKFISNKKITDTYKWKAKNLAIPLEVALLAKCRPVKGVIDM
LAFYKSDGKKGWYLIMNRIAKFVDLFDYISRAKYLSEEKAAFFFRQIIEI
LKQCHQQKVLHRDIKDENILVDENTDFVYLIDFGSGAFLKTDDYRNFDGT
RVYSPPEWIKNHCYNGFKLEVWSLGVLLFDMVCGDIPFNTDDQILNGKLK
YRHCVSADCRDLIEKCLKHDPSYRINLNEISNHPWVQKHHLNPMASTTLT
TANYPLSYINSNPIAQRSYHAISGSSSLYSPAETISSSSGDESVDEKYSQ
TIPEYFSKPRETPKFYISENEDEDSSEFPAPEIDQLKFSDNVRSHLENLN
NEYLSFTQSCIVNPQ*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0016301kinase activity
Vocabulary: biological process
TermDefinition
GO:0043066negative regulation of apoptotic process
GO:0006468protein phosphorylation
GO:0016310phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0002111X2 cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR017348PIM1/2/3
IPR000719Prot_kinase_dom
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 32..286
e-value: 2.6E-59
score: 213.0
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 32..286
e-value: 3.6E-54
score: 183.9
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 32..286
score: 39.283
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 17..119
e-value: 1.6E-22
score: 81.7
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 122..303
e-value: 7.0E-53
score: 180.7
NoneNo IPR availablePANTHERPTHR22984:SF22SERINE/THREONINE-PROTEIN KINASE PRK-2coord: 22..299
NoneNo IPR availablePANTHERPTHR22984SERINE/THREONINE PROTEIN KINASEcoord: 22..299
IPR017348Serine/threonine-protein kinase pim-1/2/3PIRSFPIRSF037993STPK_Pim-1coord: 13..306
e-value: 1.6E-81
score: 271.6
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 159..171
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 38..61
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 25..300