G_PROTEIN_RECEP_F1_2 domain-containing protein

Overview


Name	G_PROTEIN_RECEP_F1_2 domain-containing protein
Smed ID	SMED30025638
Length (bp)	605

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30025638) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G_PROTEIN_RECEP_F1_2 domain-containing protein (SMED30025638) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025638

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30025638	SMESG000003106.1	SmedASXL_007445	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
muscle cell	SMED30025638	SMESG000003106.1	dd_Smed_v4_23723_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30025638	SMESG000003106.1	dd_Smed_v6_23723_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
enteric muscle cell	SMED30025638	SMESG000003106.1	dd_Smed_v4_23723_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: CCKAR (cholecystokinin A receptor [Source:HGNC Symbol;Acc:HGNC:1570])

HSP 1 Score: 62.3882 bits (150), Expect = 5.684e-11
Identity = 43/123 (34.96%), Postives = 75/123 (60.98%), Query Frame = 3

Query:  237 ESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E+E LF     D+ R  ++    + ++ Y L+    +L N +V+ V++RNK  ++  N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:   23 ENETLFC---LDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 140

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 53.1434 bits (126), Expect = 6.238e-8
Identity = 27/75 (36.00%), Postives = 42/75 (56.00%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RNK   +  N+ ILNLAISDL++     P  L+  + +   W +G+  CK S +  G ++  S  ++  IA+DRF
Sbjct:   72 RNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIA--GWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRF 144

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 53.1434 bits (126), Expect = 6.256e-8
Identity = 27/75 (36.00%), Postives = 42/75 (56.00%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RNK   +  N+ ILNLAISDL++     P  L+  + +   W +G+  CK S +  G ++  S  ++  IA+DRF
Sbjct:   75 RNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIA--GWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRF 147

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: NPFFR2 (neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc:HGNC:4525])

HSP 1 Score: 52.7582 bits (125), Expect = 9.522e-8
Identity = 27/75 (36.00%), Postives = 42/75 (56.00%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RNK   +  N+ ILNLAISDL++     P  L+  + +   W +G+  CK S +  G ++  S  ++  IA+DRF
Sbjct:  174 RNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIA--GWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRF 246

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Match: NPY4R (neuropeptide Y receptor Y4 [Source:HGNC Symbol;Acc:HGNC:9329])

HSP 1 Score: 51.6026 bits (122), Expect = 2.032e-7
Identity = 39/135 (28.89%), Postives = 66/135 (48.89%), Query Frame = 3

Query:  198 LVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            L   L       + S+ L +     EH      ++V IV  Y +    G+L NL ++ V +R K   +  N+LI NLA SD ++C + QP   +  +  +  W +G   CK SA     ++ VS +S+ ++A++R
Sbjct:    7 LALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDY--WIFGETLCKMSAFIQCMSVTVSILSLVLVALER 139

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 63.929 bits (154), Expect = 5.596e-12
Identity = 43/127 (33.86%), Postives = 77/127 (60.63%), Query Frame = 3

Query:  234 SESEDLFSDVWQDEHRDI--EKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +E+E+   D + D+H D+  E  +LV   + Y+ +   GIL N  V+ + ++++  Q+ +N+ ILNL  S++++C  + P   I F+T+ +K W + S  CK   +  G +IFVST S++ IA+DR+
Sbjct:    3 NETEET-CDRYIDKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLP---ITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRY 125

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 63.5438 bits (153), Expect = 6.537e-12
Identity = 43/127 (33.86%), Postives = 77/127 (60.63%), Query Frame = 3

Query:  234 SESEDLFSDVWQDEHRDI--EKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +E+E+   D + D+H D+  E  +LV   + Y+ +   GIL N  V+ + ++++  Q+ +N+ ILNL  S++++C  + P   I F+T+ +K W + S  CK   +  G +IFVST S++ IA+DR+
Sbjct:   28 NETEET-CDRYIDKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLP---ITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRY 150

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-2 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:A0A061AKJ8])

HSP 1 Score: 63.5438 bits (153), Expect = 7.426e-12
Identity = 41/119 (34.45%), Postives = 72/119 (60.50%), Query Frame = 3

Query:  258 DVWQDEHRDI--EKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            D + D+H D+  E  +LV   + Y+ +   GIL N  V+ + ++++  Q+ +N+ ILNL  S++++C  + P   I F+T+ +K W + S  CK   +  G +IFVST S++ IA+DR+
Sbjct:   53 DRYIDKHPDMTNEPTVLVTFSLLYLHIFLLGILGNSAVLYLTMKHRQLQTVQNIFILNLCASNVLMCLTSLP---ITFITNVYKQWFFSSPVCKLIPLVQGASIFVSTFSLSAIALDRY 168

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-8 (Probable G-protein coupled receptor npr-8 [Source:UniProtKB/Swiss-Prot;Acc:Q18904])

HSP 1 Score: 61.2326 bits (147), Expect = 5.492e-11
Identity = 32/75 (42.67%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            R K  ++ RN+LILNLA+S+LIL     PF  +   +    + Y  F CKF+ +  G+NI+ ST++I+V+AIDR+
Sbjct:   97 RKKTMRTNRNVLILNLALSNLILAITNIPF--LWLPSIDFEFPYSRFFCKFANVLPGSNIYCSTLTISVMAIDRY 169

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Match: npr-12 (NeuroPeptide Receptor family [Source:UniProtKB/TrEMBL;Acc:V6CLI1])

HSP 1 Score: 60.8474 bits (146), Expect = 5.537e-11
Identity = 46/133 (34.59%), Postives = 72/133 (54.14%), Query Frame = 3

Query:  222 SNDSSESEDLFSDVWQDEHRDIEKHILVI------IVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
             N + +  ++  D W  E ++ +  +  I      IV  Y L+ + G L N IV+L  +R    ++ RN  I+NLA SDLILC VT P  L  + + +  W +G ++CKF A     N FVS++++  IA+DR
Sbjct:    4 PNSTGQWTEIHCD-WFAEMQNYQNSLYKINFDGSPIVPMYGLVCSFGALANFIVLLAFVRTANLRNLRNSFIVNLAFSDLILCVVTAPVTL--YTSLNLFWPFGDWSCKFLAGVQAVNTFVSSLTLAFIAMDR 133

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: NPFR (gene:FBgn0037408 transcript:FBtr0308318)

HSP 1 Score: 75.8702 bits (185), Expect = 6.772e-16
Identity = 48/112 (42.86%), Postives = 70/112 (62.50%), Query Frame = 3

Query:  276 HRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFT--CKFSAIFSGTNIFVSTISITVIAIDRF 605
            +R ++     +++  Y ++I  G L N +VV+ ++R  + ++ RN+ ILNLAISDL+LC VT P  L+  L+  K W YGS +  CK  A+     IFVSTISIT IA DR+
Sbjct:   78 NRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS--KYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRY 187

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: NPFR (gene:FBgn0037408 transcript:FBtr0308316)

HSP 1 Score: 75.485 bits (184), Expect = 6.971e-16
Identity = 48/112 (42.86%), Postives = 70/112 (62.50%), Query Frame = 3

Query:  276 HRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFT--CKFSAIFSGTNIFVSTISITVIAIDRF 605
            +R ++     +++  Y ++I  G L N +VV+ ++R  + ++ RN+ ILNLAISDL+LC VT P  L+  L+  K W YGS +  CK  A+     IFVSTISIT IA DR+
Sbjct:   78 NRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS--KYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRY 187

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: NPFR (gene:FBgn0037408 transcript:FBtr0308317)

HSP 1 Score: 75.485 bits (184), Expect = 7.133e-16
Identity = 48/112 (42.86%), Postives = 70/112 (62.50%), Query Frame = 3

Query:  276 HRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFT--CKFSAIFSGTNIFVSTISITVIAIDRF 605
            +R ++     +++  Y ++I  G L N +VV+ ++R  + ++ RN+ ILNLAISDL+LC VT P  L+  L+  K W YGS +  CK  A+     IFVSTISIT IA DR+
Sbjct:   78 NRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS--KYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRY 187

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: NPFR (gene:FBgn0037408 transcript:FBtr0078590)

HSP 1 Score: 75.485 bits (184), Expect = 7.420e-16
Identity = 48/112 (42.86%), Postives = 70/112 (62.50%), Query Frame = 3

Query:  276 HRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFT--CKFSAIFSGTNIFVSTISITVIAIDRF 605
            +R ++     +++  Y ++I  G L N +VV+ ++R  + ++ RN+ ILNLAISDL+LC VT P  L+  L+  K W YGS +  CK  A+     IFVSTISIT IA DR+
Sbjct:   78 NRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS--KYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRY 187

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Match: sNPF-R (gene:FBgn0036934 transcript:FBtr0332667)

HSP 1 Score: 60.4622 bits (145), Expect = 1.098e-10
Identity = 40/107 (37.38%), Postives = 63/107 (58.88%), Query Frame = 3

Query:  294 HILVIIVVFYVLMITC---GXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            H   + + FYVL  T    G+  N++V  V+LRN+  Q+  N+ I NLA+SD++LC +  PF  +   T    WA+G   C   +   G +I++ST+++T IAIDR+
Sbjct:   58 HNQFVQIFFYVLYATVFVLGVFGNVLVCYVVLRNRAMQTVTNIFITNLALSDILLCVLAVPFTPL--YTFMGRWAFGRSLCHLVSFAQGCSIYISTLTLTSIAIDRY 162

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: CCKAR (cholecystokinin A receptor [Source:NCBI gene;Acc:569038])

HSP 1 Score: 60.4622 bits (145), Expect = 1.660e-10
Identity = 42/132 (31.82%), Postives = 75/132 (56.82%), Query Frame = 3

Query:  210 LKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            L  C N+S+ S          E +D+ +    + +V Y L+     L N +++ V+LRN+  ++  N+ +L+LA+SDL+LC    PF LI  L   K++ +GS  CK +  F G ++ VST+++  I+++R+
Sbjct:   28 LSECKNESTPSPS--------EPKDMNQ---TVRIVLYALIFILSFLGNSLIIAVLLRNRRMRTVTNLFLLSLAVSDLMLCVFCMPFTLIPNL--MKDFIFGSGMCKVATYFMGISVSVSTLNLVAISLERY 146

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: CCKAR (cholecystokinin A receptor [Source:NCBI gene;Acc:569038])

HSP 1 Score: 60.077 bits (144), Expect = 1.742e-10
Identity = 42/132 (31.82%), Postives = 75/132 (56.82%), Query Frame = 3

Query:  210 LKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            L  C N+S+ S          E +D+ + + +   V Y L+     L N +++ V+LRN+  ++  N+ +L+LA+SDL+LC    PF LI  L   K++ +GS  CK +  F G ++ VST+++  I+++R+
Sbjct:   28 LSECKNESTPSPS--------EPKDMNQTVRI---VLYALIFILSFLGNSLIIAVLLRNRRMRTVTNLFLLSLAVSDLMLCVFCMPFTLIPNL--MKDFIFGSGMCKVATYFMGISVSVSTLNLVAISLERY 146

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: CCKAR (cholecystokinin A receptor [Source:NCBI gene;Acc:569038])

HSP 1 Score: 60.077 bits (144), Expect = 1.758e-10
Identity = 42/132 (31.82%), Postives = 75/132 (56.82%), Query Frame = 3

Query:  210 LKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            L  C N+S+ S          E +D+ +    + +V Y L+     L N +++ V+LRN+  ++  N+ +L+LA+SDL+LC    PF LI  L   K++ +GS  CK +  F G ++ VST+++  I+++R+
Sbjct:   28 LSECKNESTPSPS--------EPKDMNQ---TVRIVLYALIFILSFLGNSLIIAVLLRNRRMRTVTNLFLLSLAVSDLMLCVFCMPFTLIPNL--MKDFIFGSGMCKVATYFMGISVSVSTLNLVAISLERY 146

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: npy2r (neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GENE-040924-8])

HSP 1 Score: 56.225 bits (134), Expect = 3.578e-9
Identity = 39/141 (27.66%), Postives = 75/141 (53.19%), Query Frame = 3

Query:  183 STIENLVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
             T+  L +    C+ D++E +    D  +D  + +   + VI+++ Y  +I  G+  N +V+ V+ + +   +  N  I+NLA++DL++ ++  PF L+   T +  W +G   C       G  + VSTI++ VIA+DR+
Sbjct:   18 GTLSQLNQSTNCCAPDTAEVDAALLDGLEDSTKLV--GVQVILILAYSTIIFFGMTGNSLVIYVVYKFRNLHTVTNYFIVNLAVADLLVNTLCLPFTLM--YTLYGEWKFGQVMCYLLPYAQGLAVHVSTITLNVIALDRY 154

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Match: npy2r (neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GENE-040924-8])

HSP 1 Score: 56.225 bits (134), Expect = 3.612e-9
Identity = 39/141 (27.66%), Postives = 75/141 (53.19%), Query Frame = 3

Query:  183 STIENLVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
             T+  L +    C+ D++E +    D  +D  + +   + VI+++ Y  +I  G+  N +V+ V+ + +   +  N  I+NLA++DL++ ++  PF L+   T +  W +G   C       G  + VSTI++ VIA+DR+
Sbjct:   18 GTLSQLNQSTNCCAPDTAEVDAALLDGLEDSTKLV--GVQVILILAYSTIIFFGMTGNSLVIYVVYKFRNLHTVTNYFIVNLAVADLLVNTLCLPFTLM--YTLYGEWKFGQVMCYLLPYAQGLAVHVSTITLNVIALDRY 154

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: rpl3 (ribosomal protein L3 [Source:Xenbase;Acc:XB-GENE-971703])

HSP 1 Score: 58.151 bits (139), Expect = 1.317e-9
Identity = 38/140 (27.14%), Postives = 73/140 (52.14%), Query Frame = 3

Query:  222 SNDSSESEDLFSD-------VWQDEHRDIEKHILV-----IIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
             N SSE+ DL++        +++ E  +    +L      I V    +M+ CG    + ++ + ++ KL +S  N+LI NLA+SDL++  V  PF +  ++   ++W +G   C   +     +++VST ++  IA+DR+
Sbjct:    5 GNASSEALDLWNHSSEYNYFIYEGEGPETGGKVLFMARLFIGVTLACVMLICGFGNLIFILTLAMKKKL-RSVTNILIANLAVSDLLVAVVCCPFEMDYYVVREQSWTFGHVICSSVSYLRMVSLYVSTNALLAIAVDRY 143

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: gadd45b (growth arrest and DNA damage inducible beta [Source:Xenbase;Acc:XB-GENE-979559])

HSP 1 Score: 57.7658 bits (138), Expect = 1.491e-9
Identity = 38/126 (30.16%), Postives = 73/126 (57.94%), Query Frame = 3

Query:  228 DSSESE-DLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            DS   E + F+++ + E    +  +  +++V Y ++I   +  N++V  V+++NK   S  ++ I+NLA+SD+++  +  PF L+RF+ S   W +G   C  S      ++ VST+++T IA+DR
Sbjct:   47 DSRIGEWERFAELAKYESDAQKPTVQALLIVAYSVIIVMSLFGNMLVCHVVMKNKRMHSATSLFIVNLAVSDIMITLLNTPFTLVRFVNS--TWVFGKEMCHISRFVQYCSLHVSTLTLTAIALDR 170

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: errfi1 (ERBB receptor feedback inhibitor 1 [Source:Xenbase;Acc:XB-GENE-1005334])

HSP 1 Score: 56.6102 bits (135), Expect = 3.504e-9
Identity = 33/100 (33.00%), Postives = 57/100 (57.00%), Query Frame = 3

Query:  306 IIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +I+  Y L++  GI  N +++ VI R K   +  N L+ NLA SD+++C+   P  L  ++   + W +G F C F  +     ++VS  ++TVIA+DR+
Sbjct:   36 LIIPCYSLVVFTGIFGNYLLIYVICRTKKMHNVTNFLVGNLAFSDMLMCATCVPLTL-AYVFEPRGWVFGHFLCYFVFLMQPVTVYVSVFTLTVIAVDRY 134

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: rpl3 (ribosomal protein L3 [Source:Xenbase;Acc:XB-GENE-971703])

HSP 1 Score: 55.4546 bits (132), Expect = 9.128e-9
Identity = 37/137 (27.01%), Postives = 72/137 (52.55%), Query Frame = 3

Query:  231 SSESEDLFSD-------VWQDEHRDIEKHILV-----IIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            SSE+ DL++        +++ E  +    +L      I V    +M+ CG    + ++ + ++ KL +S  N+LI NLA+SDL++  V  PF +  ++   ++W +G   C   +     +++VST ++  IA+DR+
Sbjct:   15 SSEALDLWNHSSEYNYFIYEGEGPETGGKVLFMARLFIGVTLACVMLICGFGNLIFILTLAMKKKL-RSVTNILIANLAVSDLLVAVVCCPFEMDYYVVREQSWTFGHVICSSVSYLRMVSLYVSTNALLAIAVDRY 150

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000044281.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:115219157:115249407:-1 gene:ENSXETG00000019365.1 transcript:ENSXETT00000044281.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.4546 bits (132), Expect = 9.133e-9
Identity = 31/95 (32.63%), Postives = 53/95 (55.79%), Query Frame = 3

Query:  321 YVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            Y L++  GI  N +++ VI R +   +  N  I NLA SD+++C+   PF L  +  + + W +G F C F  +     ++VS  ++T IA+DR+
Sbjct:   41 YTLVVLIGIFGNYLLLYVICRTRKMHNVTNFFIGNLAFSDMLMCATCVPFTL-AYAFNPQGWVFGKFMCYFVFLMQPVTVYVSVFTLTAIAVDRY 134

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BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Cckar (cholecystokinin A receptor [Source:MGI Symbol;Acc:MGI:99478])

HSP 1 Score: 60.8474 bits (146), Expect = 1.263e-10
Identity = 39/123 (31.71%), Postives = 70/123 (56.91%), Query Frame = 3

Query:  237 ESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E+E LF        ++ +  + +++  F  L+   G    + V++   RNK  ++  N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:   23 ENETLFCLDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLI---RNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 140

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Cckar (cholecystokinin A receptor [Source:MGI Symbol;Acc:MGI:99478])

HSP 1 Score: 54.6842 bits (130), Expect = 1.463e-8
Identity = 28/66 (42.42%), Postives = 45/66 (68.18%), Query Frame = 3

Query:  408 NMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:    6 NIFLLSLAVSDLMLCLFCMPFNLIPNLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 69

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Opn4 (opsin 4 (melanopsin) [Source:MGI Symbol;Acc:MGI:1353425])

HSP 1 Score: 53.5286 bits (127), Expect = 4.530e-8
Identity = 30/76 (39.47%), Postives = 46/76 (60.53%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RN+  ++P NM I+NLA+SD ++ SVTQ    + F +S +K W +G   C+F A         S I++T IA+DR+
Sbjct:   96 RNRGLRTPANMFIINLAVSDFLM-SVTQ--APVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRY 168

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Opn4 (opsin 4 (melanopsin) [Source:MGI Symbol;Acc:MGI:1353425])

HSP 1 Score: 53.1434 bits (126), Expect = 4.623e-8
Identity = 30/76 (39.47%), Postives = 46/76 (60.53%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RN+  ++P NM I+NLA+SD ++ SVTQ    + F +S +K W +G   C+F A         S I++T IA+DR+
Sbjct:   96 RNRGLRTPANMFIINLAVSDFLM-SVTQ--APVFFASSLYKKWLFGETGCEFYAFCGAVFGITSMITLTAIAMDRY 168

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Match: Prokr2 (prokineticin receptor 2 [Source:MGI Symbol;Acc:MGI:2181363])

HSP 1 Score: 51.9878 bits (123), Expect = 5.842e-8
Identity = 33/101 (32.67%), Postives = 54/101 (53.47%), Query Frame = 3

Query:  300 LVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            +VI V    +M+ CGI   + +  +  R K  ++  N+LI NLAISD ++  V  PF +  ++    +WA+G   C         +++VST ++  IAIDR
Sbjct:   51 IVIGVALAGIMLVCGIGNFVFIAALA-RYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWAHGHVLCASVNYLRTVSLYVSTNALLAIAIDR 150

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9VNM1|NPFR_DROME (Neuropeptide F receptor OS=Drosophila melanogaster OX=7227 GN=NPFR PE=1 SV=3)

HSP 1 Score: 75.485 bits (184), Expect = 7.438e-15
Identity = 48/112 (42.86%), Postives = 70/112 (62.50%), Query Frame = 3

Query:  276 HRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFT--CKFSAIFSGTNIFVSTISITVIAIDRF 605
            +R ++     +++  Y ++I  G L N +VV+ ++R  + ++ RN+ ILNLAISDL+LC VT P  L+  L+  K W YGS +  CK  A+     IFVSTISIT IA DR+
Sbjct:   78 NRAVDSPWYHMLISMYGVLIVFGALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILS--KYWPYGSCSILCKTIAMLQALCIFVSTISITAIAFDRY 187

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|P32238|CCKAR_HUMAN (Cholecystokinin receptor type A OS=Homo sapiens OX=9606 GN=CCKAR PE=1 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 2.730e-10
Identity = 43/123 (34.96%), Postives = 75/123 (60.98%), Query Frame = 3

Query:  237 ESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E+E LF     D+ R  ++    + ++ Y L+    +L N +V+ V++RNK  ++  N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:   23 ENETLFC---LDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 140

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q63931|CCKAR_CAVPO (Cholecystokinin receptor type A OS=Cavia porcellus OX=10141 GN=CCKAR PE=2 SV=1)

HSP 1 Score: 62.003 bits (149), Expect = 3.813e-10
Identity = 43/123 (34.96%), Postives = 74/123 (60.16%), Query Frame = 3

Query:  237 ESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E+E LF     D  R  ++    + ++ Y L+    +L N +V+ V++RNK  ++  N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:   23 ENETLFC---LDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 140

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q18904|NPR8_CAEEL (Probable G-protein coupled receptor npr-8 OS=Caenorhabditis elegans OX=6239 GN=npr-8 PE=3 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 8.568e-10
Identity = 32/75 (42.67%), Postives = 49/75 (65.33%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            R K  ++ RN+LILNLA+S+LIL     PF  +   +    + Y  F CKF+ +  G+NI+ ST++I+V+AIDR+
Sbjct:   77 RKKTMRTNRNVLILNLALSNLILAITNIPF--LWLPSIDFEFPYSRFFCKFANVLPGSNIYCSTLTISVMAIDRY 149

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Match: sp|O08786|CCKAR_MOUSE (Cholecystokinin receptor type A OS=Mus musculus OX=10090 GN=Cckar PE=1 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 8.834e-10
Identity = 39/123 (31.71%), Postives = 70/123 (56.91%), Query Frame = 3

Query:  237 ESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E+E LF        ++ +  + +++  F  L+   G    + V++   RNK  ++  N+ +L+LA+SDL+LC    PFNLI  L   K++ +GS  CK +  F GT++ VST ++  I+++R+
Sbjct:   23 ENETLFCLDQPQPSKEWQSAVQILLYSFIFLLSVLGNTLVITVLI---RNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLL--KDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERY 140

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A183VXF4 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS5160 PE=4 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 6.733e-31
Identity = 67/131 (51.15%), Postives = 91/131 (69.47%), Query Frame = 3

Query:  228 DSSESEDLFSDVWQD--EHRDIEKHILVII---VVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +SS+ E+L S  W++  E R+  K   V+    ++ ++ MI  G   + +V+ V+LR +  ++  N+ ILNLAISDL LC +TQPFNL+R LT ++NWA G F CKFSA+F GTNIFVSTISIT IAIDRF
Sbjct:   23 NSSKREELLSIFWEEFEESRNQSKIPTVLFATTIIIFLGMILFGAFGSSLVIYVVLRKRSMRTRGNLFILNLAISDLTLCLITQPFNLLRLLTGNRNWALGLFMCKFSAMFQGTNIFVSTISITAIAIDRF 153

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A193KUW5 (NPYR-1 OS=Schmidtea mediterranea OX=79327 GN=npyr-1 PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 3.444e-30
Identity = 68/155 (43.87%), Postives = 102/155 (65.81%), Query Frame = 3

Query:  159 LSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDE---HRDIEK---HILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +  C+  P + + +V F+  C N+S     L  ++ QDE    R++ K     L+ +V+ Y+ MI  G L + +V+ V+LR+K  ++PRNM ILNLAI+DLILC+ +QPFN+IR L+ HK W +G + CK   +F+GTN+ VSTISIT IA+DR+
Sbjct:    1 MDLCKDNPKSYQLIVSFVNKCLNESFRQAYL--EILQDEMIRGRNMGKFSLSFLIPLVLSYIAMIVIGTLGSSLVIYVVLRSKTLRTPRNMFILNLAITDLILCAFSQPFNIIRLLSFHKEWIFGEWVCKLVGLFTGTNVCVSTISITAIALDRY 153

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A075A1F7 (G_PROTEIN_RECEP_F1_2 domain-containing protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=T265_12603 PE=4 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 9.262e-29
Identity = 68/154 (44.16%), Postives = 96/154 (62.34%), Query Frame = 3

Query:  162 SFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDEH------RDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            S C  + ++  +L  FL+ C N S+ ++ L + V+ +EH      R +   +L+  ++ + +MI  G   + +V+ V+LR    ++  N+ I+NLAISDL LC  TQPF L R L  H  WA GSF CKFSA+F GTNIFVSTISIT IA+DRF
Sbjct:  160 SSCNTFINSYASLRHFLENCLNASNSTQHLLNRVFDEEHSAALSHRHLPFPMLLATILVFTIMILVGTFGSGLVIFVVLRKPSMRTRSNLFIMNLAISDLTLCLFTQPFTLYRLLIGHHPWALGSFMCKFSAMFQGTNIFVSTISITAIALDRF 313

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A5J4NQ82 (G_PROTEIN_RECEP_F1_2 domain-containing protein OS=Paragonimus westermani OX=34504 GN=DEA37_0011624 PE=4 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 1.628e-27
Identity = 67/142 (47.18%), Postives = 88/142 (61.97%), Query Frame = 3

Query:  198 LVKFLKVCSNDSSESEDLFSDVWQDEHRDI--EKH----ILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            L  FL+ C N S    D    V+ +E+  +  EK     +LV  ++ + +MI  G + + +V+ VILRN   ++  N+ I+NLAISDL LC +TQPF L R L  H  W  G F CKFSA+F GTNIFVSTISIT IA+DRF
Sbjct:   27 LKTFLEQCPNISQAIRDELMRVYYEEYLILLEEKQPSLPLLVCTLIGFTIMILFGTIGSGLVIFVILRNPAMRTRSNLFIMNLAISDLTLCLITQPFTLYRLLIGHHPWTLGQFMCKFSAMFQGTNIFVSTISITAIALDRF 168

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Match: A0A193KUI1 (NPYR-2 OS=Schmidtea mediterranea OX=79327 GN=npyr-2 PE=2 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 3.084e-27
Identity = 65/147 (44.22%), Postives = 96/147 (65.31%), Query Frame = 3

Query:  180 PSTIENLVKFLKVCSNDSSESEDLFSDVWQDEHRD-----IEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            P T   L  +L +C + + + E++   V Q  +++     I   +L+ I+  Y++MI  G   +++VVLV+LR K  Q+PRN+ ILN+A++D ILC  TQPFNLIR L+ HK W YG   CK  + F+GTN+FVST+SI+ IA+DRF
Sbjct:   24 PFTYGELFDYLALCVHKT-QREEMEKIVLQHMNQNRKQARISTSVLIPILSMYIIMILFGACGSILVVLVVLRKKQMQNPRNLFILNVAVTDFILCIFTQPFNLIRLLSQHKEWVYGETLCKMVSFFTGTNMFVSTMSISAIAVDRF 169

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: opn4a (opsin 4 [Source:NCBI gene;Acc:103023553])

HSP 1 Score: 57.7658 bits (138), Expect = 1.087e-9
Identity = 30/76 (39.47%), Postives = 45/76 (59.21%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            R++  ++P NM I+NLAI+D ++C+   P   I F TS HK W +G   C+  A         S I++TVIA+DR+
Sbjct:   90 RSRTLRTPANMFIINLAITDFLMCATQSP---IFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLTVIAVDRY 162

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: prlh2r (prolactin-releasing peptide receptor-like [Source:NCBI gene;Acc:103044274])

HSP 1 Score: 56.9954 bits (136), Expect = 1.974e-9
Identity = 24/74 (32.43%), Postives = 41/74 (55.41%), Query Frame = 3

Query:  384 NKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            N+   S  N LI NLA++DL++C    P  +  +    + W +G F C+F  +     +F + +S+T IA+DR+
Sbjct:   64 NRKMHSTTNFLIGNLALADLVMCLFCVPLTVF-YAFDERGWVFGHFMCRFVTLMQTATVFAAVLSLTAIAVDRY 136

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: GPR83 (G protein-coupled receptor 83 [Source:NCBI gene;Acc:103034162])

HSP 1 Score: 56.6102 bits (135), Expect = 2.423e-9
Identity = 34/102 (33.33%), Postives = 61/102 (59.80%), Query Frame = 3

Query:  297 ILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            +  ++VV Y ++I   +  N +V  V+++NK   S  ++ I+NLAI+D+++  +  PF L+RF+ S   W +G   C  S      ++ VST+++T IA+DR
Sbjct:   89 VKALLVVAYSVIIVISLFGNTLVCHVVMKNKRMHSATSLFIVNLAIADILITLLNTPFTLVRFVNS--TWVFGRGMCHISRFVQYCSLHVSTLTLTAIALDR 188

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: GPR83 (G protein-coupled receptor 83 [Source:NCBI gene;Acc:103034162])

HSP 1 Score: 56.6102 bits (135), Expect = 2.796e-9
Identity = 34/102 (33.33%), Postives = 61/102 (59.80%), Query Frame = 3

Query:  297 ILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            +  ++VV Y ++I   +  N +V  V+++NK   S  ++ I+NLAI+D+++  +  PF L+RF+ S   W +G   C  S      ++ VST+++T IA+DR
Sbjct:   94 VKALLVVAYSVIIVISLFGNTLVCHVVMKNKRMHSATSLFIVNLAIADILITLLNTPFTLVRFVNS--TWVFGRGMCHISRFVQYCSLHVSTLTLTAIALDR 193

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Match: npffr2b (neuropeptide FF receptor 2-like [Source:NCBI gene;Acc:103031865])

HSP 1 Score: 56.225 bits (134), Expect = 3.195e-9
Identity = 36/106 (33.96%), Postives = 61/106 (57.55%), Query Frame = 3

Query:  288 EKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            E  +  I +V Y+L+    ++ N +V  ++LR+K  ++  N+ ILNLAISDL++     P  L+  + +   W +GS  CK S +  G ++  S  ++ VIA+DRF
Sbjct:   50 EPSVSAIFIVSYLLIFVVCMVGNGLVCFIVLRSKSMRTVTNLFILNLAISDLLVGIFCMPTTLVDNIIT--GWPFGSLVCKLSGMVQGISVSASVFTLVVIAVDRF 153

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: prlh2r (prolactin releasing hormone 2 receptor [Source:ZFIN;Acc:ZDB-GENE-120411-41])

HSP 1 Score: 63.929 bits (154), Expect = 1.145e-12
Identity = 37/99 (37.37%), Postives = 62/99 (62.63%), Query Frame = 3

Query:  309 IVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +V+FY  ++  G+L N ++V VI R K   +  N+LI NLA SDL++C++  P  L  ++   + W +GSF C F  +    +++VS  ++TVIA+DR+
Sbjct:   24 VVLFYTAVVVVGVLGNFLLVYVICRVKKMHNVTNLLIGNLAFSDLLMCAMCVPLTLA-YVFDARGWVFGSFMCYFVFLMQPVSVYVSVFTLTVIAVDRY 121

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: si:dkey-202l22.3 (prolactin releasing hormone receptor [Source:HGNC Symbol;Acc:HGNC:4464])

HSP 1 Score: 56.9954 bits (136), Expect = 3.950e-10
Identity = 35/100 (35.00%), Postives = 55/100 (55.00%), Query Frame = 3

Query:  306 IIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            I +  Y L+   G+  NL+++LVI R K   +  N L+ NLA+SDL++C    P +   F    + W YG+  C   A+     + VS +S+T IA+DR+
Sbjct:   69 IFIPLYALLTLVGVSGNLLLILVIARTKRLHNATNFLLGNLALSDLLVCLTCVPIS-AAFAFEPRGWVYGALLCYLVALLQPATVHVSVLSLTAIALDRY 167

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: npffr1l3 (neuropeptide FF receptor 1 like 3 [Source:ZFIN;Acc:ZDB-GENE-070424-44])

HSP 1 Score: 52.373 bits (124), Expect = 1.338e-8
Identity = 32/124 (25.81%), Postives = 63/124 (50.81%), Query Frame = 3

Query:  234 SESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            S +   F   +Q        +++  + +F + MI  G++  +++     +++  ++  N+ ILNLA+SDL++     P  L+  L +   W +G   CK S +  GT++  S  ++  IA+DRF
Sbjct:   32 SATNATFYTFYQHAPPTAAVYLIAYLFIFLLCMIGNGLVCYVVL-----QSRRMRTVTNLFILNLAVSDLLVGIFCMPITLVDNLIT--GWPFGVVVCKMSGLVQGTSVSASVFTLVAIAVDRF 148

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: opn4a (opsin 4a (melanopsin) [Source:NCBI gene;Acc:571624])

HSP 1 Score: 48.1358 bits (113), Expect = 4.348e-7
Identity = 29/76 (38.16%), Postives = 43/76 (56.58%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            R+K  +SP N+ I+NLA +D  + S+TQ    I F+TS HK W +G   C+  A         S +++ VIA DR+
Sbjct:   41 RSKSLRSPANIFIINLAFADFFM-SITQ--TPIFFVTSLHKRWIFGEKGCELYAFCGALFGIASMVTLMVIATDRY 113

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Match: npy8br (neuropeptide Y receptor Y8b [Source:ZFIN;Acc:ZDB-GENE-980526-208])

HSP 1 Score: 46.9802 bits (110), Expect = 9.502e-7
Identity = 36/110 (32.73%), Postives = 60/110 (54.55%), Query Frame = 3

Query:  273 EHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            +H    + +   ++  Y ++I  G+L N ++VLVILR+    +  N+LI+NLA SD+++  V  P  +   L  H  W +G   CK S     + + VS  S+ +IAI+R
Sbjct:   29 DHCQTPQAVRSFVIATYCVLIALGLLGNSLLVLVILRHSELHNVTNILIVNLAFSDMLVGLVCLPLTIAYTLMDH--WIFGEALCKGSPFLQCSAVSVSIFSLVLIAIER 136

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO39743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S993])

HSP 1 Score: 48.9062 bits (115), Expect = 6.537e-8
Identity = 26/75 (34.67%), Postives = 40/75 (53.33%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            RN   +S  N+ I NLA +DL +  +  PFN+++     +NW +G   CK      G  +  S  S+ VIA+DR+
Sbjct:   17 RNPRMKSVTNLFIANLAFADLNVVLINVPFNVLKL--KLENWPFGLVICKIVTSLLGITLSASVGSLIVIAVDRY 89

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO48802 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIF2])

HSP 1 Score: 49.2914 bits (116), Expect = 2.815e-7
Identity = 40/127 (31.50%), Postives = 62/127 (48.82%), Query Frame = 3

Query:  225 NDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            N+S+  E L  D            I    +  Y L+   G+  N +V  +IL+N    S     ILNLAISDL+   +  PF+L+ +L +   W +G+F CKF    S  ++ VS  ++  I+ DR+
Sbjct:    2 NNSTVGETLMED---------PPAIRYTRLFLYPLIFAVGVAGNSLVCALILKNGKSSSANGYFILNLAISDLMALLLYLPFDLV-YLENSYIWPFGTFLCKFINCLSKVSVTVSGSTLVAISYDRY 118

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO34678 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNL7])

HSP 1 Score: 46.2098 bits (108), Expect = 2.083e-6
Identity = 30/69 (43.48%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  411 MLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCK----FSAIFSGTNIFVSTISITVIAIDRF 605
            + +LNLAI+DL +   + PF L+R  T   +W +G F CK    FS IF G    VS  SIT IA+ R+
Sbjct:    1 VFVLNLAIADLGVLIFSVPFGLVR--TEAISWPFGWFGCKVLYPFSDIFHG----VSIASITAIAVYRY 63

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO36556 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIA0])

HSP 1 Score: 46.2098 bits (108), Expect = 2.747e-6
Identity = 25/63 (39.68%), Postives = 39/63 (61.90%), Query Frame = 3

Query:  417 ILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            ILNL+ISDL++  +  PF+L  +L +   W YG F CKF    S  ++ VS  ++  I++DR+
Sbjct:   59 ILNLSISDLLVLIMFIPFDLA-YLENDMVWKYGLFMCKFINTLSFLSVIVSGTTLAAISVDRY 120

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Match: EDO47026 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN98])

HSP 1 Score: 45.8246 bits (107), Expect = 3.763e-6
Identity = 34/99 (34.34%), Postives = 53/99 (53.54%), Query Frame = 3

Query:  321 YVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNW----AYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            Y+L++   ++ NL VVL++ +NK  Q+  N LI+N+A+SD++   +  P  ++        W      G F+CK  A        VS  S+ VIAIDRF
Sbjct:    3 YLLIMVLALVGNLFVVLIVYKNKSMQTTVNYLIVNMAVSDMLQSFIAIPKRVMEIYAGSHRWLIHGVAGEFSCKSVAFLQDIGTAVSIQSLVVIAIDRF 101

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: GPR83 (G protein-coupled receptor 83 [Source:NCBI gene;Acc:101172125])

HSP 1 Score: 60.077 bits (144), Expect = 1.834e-10
Identity = 36/105 (34.29%), Postives = 62/105 (59.05%), Query Frame = 3

Query:  288 EKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            +  + V++V  Y L+I   +  N +V  V+++NK  QS  ++ ILNLA++D+ +  +  PF L+RF+  H  W +G   C  S      ++ VST+++T IA+DR
Sbjct:   81 DSGVKVLLVAAYSLIIVISLFGNTLVCHVVVKNKSTQSSTSLFILNLAVADIFITVLNTPFTLVRFV--HSTWVFGRAMCHISRFVQYCSLHVSTLTLTAIALDR 183

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: opn4a (melanopsin-A [Source:NCBI gene;Acc:101165418])

HSP 1 Score: 57.7658 bits (138), Expect = 1.152e-9
Identity = 32/76 (42.11%), Postives = 45/76 (59.21%), Query Frame = 3

Query:  381 RNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTS-HKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            R++  ++P NM I+NLAI+DL++C    P   I F TS HK W +G   C+  A         S I++TVIAIDR+
Sbjct:   46 RSRSLRTPANMFIINLAITDLLMCVTQSP---IFFTTSMHKRWIFGEKGCELYAFCGALFGICSMITLTVIAIDRY 118

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: opn4xa (melanopsin-B [Source:NCBI gene;Acc:101158465])

HSP 1 Score: 55.8398 bits (133), Expect = 3.967e-9
Identity = 35/111 (31.53%), Postives = 55/111 (49.55%), Query Frame = 3

Query:  273 EHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
             H D+  H+  II  F +++ T G+  N +V+     NK  ++P N  I+NLA+SD ++     P   I  L  +K W +G   CK  A         S I++  I+IDR+
Sbjct:    9 RHVDVPDHVHYIIAFFVLVIGTVGVTGNALVMYAFSCNKKLRTPPNFFIMNLAVSDFLMAITQSPIFFINCL--YKGWIFGETGCKMYAFCGALFGISSMINLLAISIDRY 117

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: opn4.1 (opsin 4.1 [Source:NCBI gene;Acc:352918])

HSP 1 Score: 54.299 bits (129), Expect = 1.806e-8
Identity = 34/107 (31.78%), Postives = 56/107 (52.34%), Query Frame = 3

Query:  282 DIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            D+  H   II    +L+   G+L N +V+ V  R+K  +SP N+L++NLA +D ++     P   +  L  H+ W +G F C+  A         S +++T IA+DR
Sbjct:   23 DVPDHAHYIIGCVILLVGMTGMLGNALVIYVFCRSKALRSPSNLLVVNLAAADFLMSVTQSPAFFVASL--HRGWVFGEFACELYAFCGALFGITSMMTLTAIAVDR 127

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Match: si:ch73-160i9.1 (C3a anaphylatoxin chemotactic receptor [Source:NCBI gene;Acc:101158210])

HSP 1 Score: 52.7582 bits (125), Expect = 4.989e-8
Identity = 41/112 (36.61%), Postives = 63/112 (56.25%), Query Frame = 3

Query:  267 QDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDR 602
            Q  + D+E  +  I ++ Y L +  GI  N +V+ V    KL     N+ ++NLAI+DLI C  T+ F+LI+ L    +W +G F CKF+  F   N+F S   + VI++DR
Sbjct:   18 QAANVDMEAIMENISIILYTLTVVLGITGNSVVIWVAG-FKLKPKVTNVWLVNLAIADLIFC-FTRVFSLIKKLF-FDHWPFGVFLCKFNGFFKYANMFCSVFLLAVISLDR 126

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000003106.1 (SMESG000003106.1)

HSP 1 Score: 303.523 bits (776), Expect = 9.078e-103
Identity = 161/161 (100.00%), Postives = 161/161 (100.00%), Query Frame = 3

Query:  123 MNAVHNDSLQALLSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            MNAVHNDSLQALLSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGILENLIVVLVILRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF
Sbjct:    1 MNAVHNDSLQALLSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDEHRDIEKHILVIIVVFYVLMITCGILENLIVVLVILRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 161

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000053241.1 (SMESG000053241.1)

HSP 1 Score: 124.02 bits (310), Expect = 9.579e-34
Identity = 68/155 (43.87%), Postives = 102/155 (65.81%), Query Frame = 3

Query:  159 LSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQDE---HRDIEK---HILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +  C+  P + + +V F+  C N+S     L  ++ QDE    R++ K     L+ +V+ Y+ MI  G L + +V+ V+LR+K  ++PRNM ILNLAI+DLILC+ +QPFN+IR L+ HK W +G + CK   +F+GTN+ VSTISIT IA+DR+
Sbjct:    1 MDLCKDNPKSYQLIVSFVNKCLNESFRQAYL--EILQDEMIRGRNMGKFSLSFLIPLVLSYIAMIVIGTLGSSLVIYVVLRSKTLRTPRNMFILNLAITDLILCAFSQPFNIIRLLSFHKEWIFGEWVCKLVGLFTGTNVCVSTISITAIALDRY 153

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000052051.1 (SMESG000052051.1)

HSP 1 Score: 117.087 bits (292), Expect = 7.984e-31
Identity = 65/147 (44.22%), Postives = 96/147 (65.31%), Query Frame = 3

Query:  180 PSTIENLVKFLKVCSNDSSESEDLFSDVWQDEHRD-----IEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            P T   L  +L +C + + + E++   V Q  +++     I   +L+ I+  Y++MI  G   +++VVLV+LR K  Q+PRN+ ILN+A++D ILC  TQPFNLIR L+ HK W YG   CK  + F+GTN+FVST+SI+ IA+DRF
Sbjct:   24 PFTYGELFDYLALCVHKT-QREEMEKIVLQHMNQNRKQARISTSVLIPILSMYIIMILFGACGSILVVLVVLRKKQMQNPRNLFILNVAVTDFILCIFTQPFNLIRLLSQHKEWVYGETLCKMVSFFTGTNMFVSTMSISAIAVDRF 169

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000004267.1 (SMESG000004267.1)

HSP 1 Score: 110.923 bits (276), Expect = 1.623e-28
Identity = 62/146 (42.47%), Postives = 88/146 (60.27%), Query Frame = 3

Query:  186 TIENLVKFLKVCSNDSSESEDLFSDVWQD------EHRDIEKHILVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            +IE ++ + K C   +    + F  V +D      +   +E   L+ I+  ++LMI  G+  N +VV  ++R +  Q+ RN+ ILNLAISDL LC  TQPFNL+R L  +  W YG   CK SA+  GTN+FVSTI+IT IA+DRF
Sbjct:   23 SIEMMINYYKYCGQFTDIERETFIQVIKDSIPKPNKLEKLELAGLITILTIFILMIIFGVFGNALVVFAVMRYRQLQTARNVFILNLAISDLCLCIFTQPFNLLRLLVKYHPWTYGDVLCKMSALLQGTNVFVSTITITAIALDRF 168

[Close]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Match: SMESG000078214.1 (SMESG000078214.1)

HSP 1 Score: 108.997 bits (271), Expect = 2.457e-28
Identity = 59/153 (38.56%), Postives = 94/153 (61.44%), Query Frame = 3

Query:  168 CQHYPSTIENLVKF-LKVCSNDSSESEDLFSDVWQDEHRDIEKHI------LVIIVVFYVLMITCGXXXXXXXXXXXXRNKLFQSPRNMLILNLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVSTISITVIAIDRF 605
            C+       +L+K+ L  C+  ++E+  +   V  +  +  E  +       + ++V Y +MI  G + + +V+LV+ +NK+ ++PRN+ ILNL ISDLILC+ T+PFNL+R L+ H+ W  G   CK +++  GTNI VST SIT IA+DRF
Sbjct:    9 CKSIKLVTYDLIKYYLTNCAVFTNETTKVMESVLSEMKKAGENQLKLPNSFFIPLLVIYGIMIIYGSIGSFMVILVVAKNKMMRTPRNLFILNLGISDLILCAFTEPFNLLRLLSGHQEWNLGETICKLTSMLQGTNILVSTFSITAIALDRF 161

The following BLAST results are available for this feature:

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CCKAR	5.684e-11	34.96	cholecystokinin A receptor [Source:HGNC Symbol;Acc...	[more]
NPFFR2	6.238e-8	36.00	neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc...	[more]
NPFFR2	6.256e-8	36.00	neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc...	[more]
NPFFR2	9.522e-8	36.00	neuropeptide FF receptor 2 [Source:HGNC Symbol;Acc...	[more]
NPY4R	2.032e-7	28.89	neuropeptide Y receptor Y4 [Source:HGNC Symbol;Acc...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
npr-2	5.596e-12	33.86	NeuroPeptide Receptor family [Source:UniProtKB/Tr...	[more]
npr-2	6.537e-12	33.86	NeuroPeptide Receptor family [Source:UniProtKB/Tr...	[more]
npr-2	7.426e-12	34.45	NeuroPeptide Receptor family [Source:UniProtKB/Tr...	[more]
npr-8	5.492e-11	42.67	Probable G-protein coupled receptor npr-8 [Source...	[more]
npr-12	5.537e-11	34.59	NeuroPeptide Receptor family [Source:UniProtKB/Tr...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NPFR	6.772e-16	42.86	gene:FBgn0037408 transcript:FBtr0308318	[more]
NPFR	6.971e-16	42.86	gene:FBgn0037408 transcript:FBtr0308316	[more]
NPFR	7.133e-16	42.86	gene:FBgn0037408 transcript:FBtr0308317	[more]
NPFR	7.420e-16	42.86	gene:FBgn0037408 transcript:FBtr0078590	[more]
sNPF-R	1.098e-10	37.38	gene:FBgn0036934 transcript:FBtr0332667	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CCKAR	1.660e-10	31.82	cholecystokinin A receptor [Source:NCBI gene;Acc:5...	[more]
CCKAR	1.742e-10	31.82	cholecystokinin A receptor [Source:NCBI gene;Acc:5...	[more]
CCKAR	1.758e-10	31.82	cholecystokinin A receptor [Source:NCBI gene;Acc:5...	[more]
npy2r	3.578e-9	27.66	neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GE...	[more]
npy2r	3.612e-9	27.66	neuropeptide Y receptor Y2 [Source:ZFIN;Acc:ZDB-GE...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rpl3	1.317e-9	27.14	ribosomal protein L3 [Source:Xenbase;Acc:XB-GENE-9...	[more]
gadd45b	1.491e-9	30.16	growth arrest and DNA damage inducible beta [Sourc...	[more]
errfi1	3.504e-9	33.00	ERBB receptor feedback inhibitor 1 [Source:Xenbase...	[more]
rpl3	9.128e-9	27.01	ribosomal protein L3 [Source:Xenbase;Acc:XB-GENE-9...	[more]
ENSXETT00000044281.1	9.133e-9	32.63	pep primary_assembly:Xenopus_tropicalis_v9.1:3:115...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cckar	1.263e-10	31.71	cholecystokinin A receptor [Source:MGI Symbol;Acc:...	[more]
Cckar	1.463e-8	42.42	cholecystokinin A receptor [Source:MGI Symbol;Acc:...	[more]
Opn4	4.530e-8	39.47	opsin 4 (melanopsin) [Source:MGI Symbol;Acc:MGI:13...	[more]
Opn4	4.623e-8	39.47	opsin 4 (melanopsin) [Source:MGI Symbol;Acc:MGI:13...	[more]
Prokr2	5.842e-8	32.67	prokineticin receptor 2 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9VNM1\|NPFR_DROME	7.438e-15	42.86	Neuropeptide F receptor OS=Drosophila melanogaster...	[more]
sp\|P32238\|CCKAR_HUMAN	2.730e-10	34.96	Cholecystokinin receptor type A OS=Homo sapiens OX...	[more]
sp\|Q63931\|CCKAR_CAVPO	3.813e-10	34.96	Cholecystokinin receptor type A OS=Cavia porcellus...	[more]
sp\|Q18904\|NPR8_CAEEL	8.568e-10	42.67	Probable G-protein coupled receptor npr-8 OS=Caeno...	[more]
sp\|O08786\|CCKAR_MOUSE	8.834e-10	31.71	Cholecystokinin receptor type A OS=Mus musculus OX...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A183VXF4	6.733e-31	51.15	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
A0A193KUW5	3.444e-30	43.87	NPYR-1 OS=Schmidtea mediterranea OX=79327 GN=npyr-...	[more]
A0A075A1F7	9.262e-29	44.16	G_PROTEIN_RECEP_F1_2 domain-containing protein (Fr...	[more]
A0A5J4NQ82	1.628e-27	47.18	G_PROTEIN_RECEP_F1_2 domain-containing protein OS=...	[more]
A0A193KUI1	3.084e-27	44.22	NPYR-2 OS=Schmidtea mediterranea OX=79327 GN=npyr-...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
opn4a	1.087e-9	39.47	opsin 4 [Source:NCBI gene;Acc:103023553]	[more]
prlh2r	1.974e-9	32.43	prolactin-releasing peptide receptor-like [Source:...	[more]
GPR83	2.423e-9	33.33	G protein-coupled receptor 83 [Source:NCBI gene;Ac...	[more]
GPR83	2.796e-9	33.33	G protein-coupled receptor 83 [Source:NCBI gene;Ac...	[more]
npffr2b	3.195e-9	33.96	neuropeptide FF receptor 2-like [Source:NCBI gene;...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
prlh2r	1.145e-12	37.37	prolactin releasing hormone 2 receptor [Source:ZFI...	[more]
si:dkey-202l22.3	3.950e-10	35.00	prolactin releasing hormone receptor [Source:HGNC ...	[more]
npffr1l3	1.338e-8	25.81	neuropeptide FF receptor 1 like 3 [Source:ZFIN;Acc...	[more]
opn4a	4.348e-7	38.16	opsin 4a (melanopsin) [Source:NCBI gene;Acc:571624...	[more]
npy8br	9.502e-7	32.73	neuropeptide Y receptor Y8b [Source:ZFIN;Acc:ZDB-G...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39743	6.537e-8	34.67	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48802	2.815e-7	31.50	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34678	2.083e-6	43.48	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36556	2.747e-6	39.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47026	3.763e-6	34.34	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GPR83	1.834e-10	34.29	G protein-coupled receptor 83 [Source:NCBI gene;Ac...	[more]
opn4a	1.152e-9	42.11	melanopsin-A [Source:NCBI gene;Acc:101165418]	[more]
opn4xa	3.967e-9	31.53	melanopsin-B [Source:NCBI gene;Acc:101158465]	[more]
opn4.1	1.806e-8	31.78	opsin 4.1 [Source:NCBI gene;Acc:352918]	[more]
si:ch73-160i9.1	4.989e-8	36.61	C3a anaphylatoxin chemotactic receptor [Source:NCB...	[more]

BLAST of G_PROTEIN_RECEP_F1_2 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000003106.1	9.078e-103	100.00	SMESG000003106.1	[more]
SMESG000053241.1	9.579e-34	43.87	SMESG000053241.1	[more]
SMESG000052051.1	7.984e-31	44.22	SMESG000052051.1	[more]
SMESG000004267.1	1.623e-28	42.47	SMESG000004267.1	[more]
SMESG000078214.1	2.457e-28	38.56	SMESG000078214.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025638 ID=SMED30025638|Name=G_PROTEIN_RECEP_F1_2 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=605bp
CGGAAAATCTAGCGATTTCAATCCACCAATAATATCAAACTTCCTATTAA
TAAAATGACATATAGTAAAATATTTTCTTAGCCCTTCTCAGTAGATTAGA
ATTGAGATTTATATGTATTAAAATGAATGCAGTTCACAACGATTCGTTGC
AAGCTCTGCTGTCATTTTGCCAGCATTACCCGTCGACTATTGAGAATTTG
GTGAAATTCCTCAAGGTTTGTTCCAATGACTCTTCAGAATCTGAAGACTT
ATTCTCCGATGTTTGGCAAGACGAGCATCGAGACATAGAGAAACACATTC
TTGTCATAATCGTTGTTTTCTACGTGTTAATGATTACTTGCGGAATACTG
GAAAATCTGATTGTCGTGTTGGTGATCTTAAGGAATAAACTCTTTCAAAG
CCCAAGAAATATGTTGATTCTTAACTTGGCGATCTCAGATTTGATCTTGT
GCAGCGTCACTCAGCCGTTCAATTTGATCCGGTTTCTCACGTCCCACAAA
AATTGGGCTTACGGAAGTTTCACTTGTAAATTTTCGGCGATTTTCAGCGG
GACGAACATTTTTGTCAGCACAATCAGCATCACCGTGATAGCGATTGATC
GATTC

protein sequence of SMED30025638-orf-1

>SMED30025638-orf-1 ID=SMED30025638-orf-1|Name=SMED30025638-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=161bp
MNAVHNDSLQALLSFCQHYPSTIENLVKFLKVCSNDSSESEDLFSDVWQD
EHRDIEKHILVIIVVFYVLMITCGILENLIVVLVILRNKLFQSPRNMLIL
NLAISDLILCSVTQPFNLIRFLTSHKNWAYGSFTCKFSAIFSGTNIFVST
ISITVIAIDRF

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000418	head
PLANA:0003104	enteric muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR000276	GPCR_Rhodpsn
IPR017452	GPCR_Rhodpsn_7TM

Vocabulary: **molecular function**
Term	Definition
GO:0004930	G-protein coupled receptor activity
GO:0004871	signal transducer activity

Vocabulary: **cellular component**
Term	Definition
GO:0016021	integral component of membrane
GO:0016020	membrane

Vocabulary: **biological process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007165	signal transduction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000276	G protein-coupled receptor, rhodopsin-like	PRINTS	PR00237	GPCRRHODOPSN	coord: 95..116 score: 31.86 coord: 142..161 score: 23.92 coord: 62..86 score: 23.48
IPR000276	G protein-coupled receptor, rhodopsin-like	PFAM	PF00001	7tm_1	coord: 77..161 e-value: 4.2E-18 score: 65.6
None	No IPR available	GENE3D	G3DSA:1.20.1070.10		coord: 25..161 e-value: 3.0E-29 score: 103.6
None	No IPR available	PANTHER	PTHR24235:SF7	NEUROPEPTIDE F RECEPTOR	coord: 33..161
None	No IPR available	PANTHER	PTHR24235	FAMILY NOT NAMED	coord: 33..161
None	No IPR available	CDD	cd15203	7tmA_NPYR-like	coord: 61..161 e-value: 4.98006E-35 score: 121.557
None	No IPR available	SUPERFAMILY	SSF81321	Family A G protein-coupled receptor-like	coord: 56..161
None	No IPR available	TMHMM	TMhelix		coord: 139..158
None	No IPR available	TMHMM	TMhelix		coord: 62..84
None	No IPR available	TMHMM	TMhelix		coord: 97..119
IPR017452	GPCR, rhodopsin-like, 7TM	PROSITE	PS50262	G_PROTEIN_RECEP_F1_2	coord: 77..161 score: 18.927

Main menu

G_PROTEIN_RECEP_F1_2 domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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