pi3k-like protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025635 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of pi3k-like protein vs. Ensembl Human
Match: PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975]) HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0 Identity = 378/1054 (35.86%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + +++ LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + ++ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R +KAI RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Human
Match: PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:8975]) HSP 1 Score: 519.235 bits (1336), Expect = 1.150e-166 Identity = 342/982 (34.83%), Postives = 522/982 (53.16%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAY 2999
+ V LLPN + R+A+L IK L KE + +++ LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + ++ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R +KAI RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + K EF G+ +
Sbjct: 20 ILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQ---ECTKTREFESSQGECF 985
BLAST of pi3k-like protein vs. Ensembl Human
Match: PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:8976]) HSP 1 Score: 464.922 bits (1195), Expect = 1.345e-149 Identity = 271/706 (38.39%), Postives = 406/706 (57.51%), Query Frame = 3
Query: 1197 VRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-------------------KTERGGNEVL--LGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINI---SKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWV-PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
VR +F+G S + + WNE L FDI ++PR A+LCF++ +T R +V + W N +F++ G+L G I L+ W + NP G+ T+ Y N+ L + K YYY R G + +K I+DRD L +L E ++D + + ++C + P+SLP+L SI+WN + +V +LL WP++ +L+LL N+ D+ +R++AV LR +++ +++ YLLQLVQ LKYE + LS FLL+ AL N+++GQ FW L+SE+H ++ + F ++LEA+CRG + M V+ Q + KL ++ ++K L + KE LK + E ++ S LN + VE C SK +P++L + N +F E S+ IFK GDDLRQD+LTLQ+L + D +WK D+++LPYGCLATG SG+IE V ++T+ IQ SN+ AA N +L W++ N + + +A+E FT SCAGY VA+++LGI DRH DNIMV GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + ++ KF F C AYL LR H +L +TL+++M+ +GLPELT V+D++YL+ +L++ E+ AL F ++F +A R +WTTK++W++H
Sbjct: 2 VRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPY-TENATALHVKFPENKKQPYYYPPFDKSR--GG--KKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNK-VFGEDSVGV---IFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYN-SGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG--KTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAH 694
BLAST of pi3k-like protein vs. Ensembl Human
Match: PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:8976]) HSP 1 Score: 473.781 bits (1218), Expect = 1.096e-148 Identity = 293/815 (35.95%), Postives = 451/815 (55.34%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFP---------ILSLYPREYLE-NISINRFI--IPPYFYQNIPQTKRRTRQDSV----SKMFSLLLISA-QLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-------------------KTERGGNEV--LLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINIS---KVNYYYQE-----QSPVRIMGSPISTTIQR--------IKAIIDRDWLYELSEQDIDYLRSNLENCLWV-PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P I +Y +E + +INR +P +P ++TR S + F ++L+ +L +E K++VR +F+G S + + WNE L FDI ++PR A+LCF++ +T R +V + W N +F++ G+L G I L+ W + NP G+ T+ Y N+ L + K YYY + I S + R +K I+DRD L +L E ++D + + ++C + P+SLP+L SI+WN + +V +LL WP++ +L+LL N+ D+ +R++AV LR +++ +++ YLLQLVQ LKYE + LS FLL+ AL N+++GQ FW L+SE+H ++ + F ++LEA+CRG + M V+ Q + KL ++ ++K L + KE LK + E ++ S LN + VE C SK +P++L + N +F E S+ IFK GDDLRQD+LTLQ+L + D +WK D+++LPYGCLATG SG+IE V ++T+ IQ SN+ AA N +L W++ N + + +A+E FT SCAGY VA+++LGI DRH DNIMV GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + ++ KF F C AYL LR H +L +TL+++M+ +GLPELT V+D++YL+ +L++ E+ AL F ++F +A R +WTTK++W++H
Sbjct: 263 LIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLP------LPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPY-TENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNK-VFGEDSV---GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYN-SGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG--KTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAH 1062
BLAST of pi3k-like protein vs. Ensembl Human
Match: PIK3CB (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:8976]) HSP 1 Score: 473.781 bits (1218), Expect = 1.096e-148 Identity = 293/815 (35.95%), Postives = 451/815 (55.34%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFP---------ILSLYPREYLE-NISINRFI--IPPYFYQNIPQTKRRTRQDSV----SKMFSLLLISA-QLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-------------------KTERGGNEV--LLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINIS---KVNYYYQE-----QSPVRIMGSPISTTIQR--------IKAIIDRDWLYELSEQDIDYLRSNLENCLWV-PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P I +Y +E + +INR +P +P ++TR S + F ++L+ +L +E K++VR +F+G S + + WNE L FDI ++PR A+LCF++ +T R +V + W N +F++ G+L G I L+ W + NP G+ T+ Y N+ L + K YYY + I S + R +K I+DRD L +L E ++D + + ++C + P+SLP+L SI+WN + +V +LL WP++ +L+LL N+ D+ +R++AV LR +++ +++ YLLQLVQ LKYE + LS FLL+ AL N+++GQ FW L+SE+H ++ + F ++LEA+CRG + M V+ Q + KL ++ ++K L + KE LK + E ++ S LN + VE C SK +P++L + N +F E S+ IFK GDDLRQD+LTLQ+L + D +WK D+++LPYGCLATG SG+IE V ++T+ IQ SN+ AA N +L W++ N + + +A+E FT SCAGY VA+++LGI DRH DNIMV GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + ++ KF F C AYL LR H +L +TL+++M+ +GLPELT V+D++YL+ +L++ E+ AL F ++F +A R +WTTK++W++H
Sbjct: 263 LIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLP------LPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPY-TENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNK-VFGEDSV---GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYN-SGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG--KTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAH 1062
BLAST of pi3k-like protein vs. Ensembl Celegans
Match: age-1 (Phosphatidylinositol 3-kinase age-1 [Source:UniProtKB/Swiss-Prot;Acc:Q94125]) HSP 1 Score: 325.865 bits (834), Expect = 6.962e-94 Identity = 215/736 (29.21%), Postives = 371/736 (50.41%), Query Frame = 3
Query: 1191 LYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKL-NFDIYYSNIPRNAKLCFSLI-EKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQ------------SPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWV---------PESLPRLAK-SIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSE--------MHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNII---AAMQMNSSSLYRWIQA-------------------------NNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEK-AALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+YVR+ + T + ++ V++ WN+++ FD+Y ++P +A L ++ K + E +GW N+++ ++ +L +G +LW E + G+ ++ +S +V Q Q + IMG + I R L + E I L + + +W+ P+ L L++ + W + + Y +L KW ++ ++L LL D+V+R+FAV+ L L+ +L++L L+QALKYE +++ + LL AL + ++G + FW L++E + +E + +L++EA+ RG + +I Q +++L IS ++K +D+ L++ L++ + +N+ S L+ K G +I++ V S KRP+ L W+N + S+ +P IFK GDDLRQD+L LQ+L + D IWK D L PY L G+ GIIE V + KT+ IQ A ++ S + +WI+ N + +++ ++++ F SC GYSVAT+I+GI+DRH DN+M+ G+ FHIDFGHIL + K K G+ R+R PF+LTE F+ I G +S + +F LC +AY + + L ++L+++M+ LPEL+ DL++L+KTL + K A +F + +A+ G+W+TK +WL H
Sbjct: 447 MYVRIEFSVYVGTLTLASKSTTKVNAQFAKWNKEMYTFDLYMKDMPPSAVLSIRVLYGKVKLKSEEFEVGWVNMSLTDWRDELRQGQFLFHLWAPEPTANRSRIGENGARIGTNAAVTIEISSYGGRVRMPSQGQYTYLVKHRSTWTETLNIMGDDYESCI-RDPGYKKLQMLVKKHESGI-VLEEDEQRHVWMWRRYIQKQEPDLLIVLSELAFVWTDRENFSELYVMLEKWKPPSVAAALTLLGKRCTDRVIRKFAVEKLNEQLSPVTFHLFILPLIQALKYEPRAQSEVGMMLLTRALCDYRIGHRLFWLLRAEIARLRDCDLKSEEYR-RISLLMEAYLRGNEEHIKIITRQVDMVDELTRISTLVKGMPKDVATMKLRDELRS--ISHKMENMDSPLDPVYKLGEMIIDKAIVLGSAKRPLMLHWKNKNPKSDLHLPFCAMIFKNGDDLRQDMLVLQVLEVMDNIWKAANIDCCLNPYAVLPMGEMIGIIEVVPNCKTIFEIQVGTGFMNTAVRSIDPSFMNKWIRKQCGIEDEKKKSKKDSTKNPIEKKIDNTQAMKKYFESVDRFLYSCVGYSVATYIMGIKDRHSDNLMLTEDGKYFHIDFGHILGHGKTKLGIQRDRQPFILTEHFMTVIRSGKSVDGNSHELQKFKTLCVEAYEVMWNNRDLFVSLFTLMLGMELPELSTKADLDHLKKTLFCNGESKEEARKFFAGIYEEAFNGSWSTKTNWLFH 1177
BLAST of pi3k-like protein vs. Ensembl Celegans
Match: piki-1 (Phosphatidylinositol 3-kinase piki-1 [Source:UniProtKB/Swiss-Prot;Acc:G5EDY0]) HSP 1 Score: 172.555 bits (436), Expect = 2.949e-43 Identity = 176/753 (23.37%), Postives = 344/753 (45.68%), Query Frame = 3
Query: 1014 LSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQK-SSLVSSDHPTWNEKLNFDIY-------YSNIPRNAKLCFSL---IEKTERGGNE-----VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNS--VILSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSE-QDIDYLRSNLENCLWV--------PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLY--LLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIK-IYFALMLEAFCRGYL------NFMTVIRPQSIGIEKLVEISRILKAQREDLQ---LSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNE-FMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVE-SDEKAALNY 3149
L LY R +++R+ IPP P+ + ++ D + M + + + + S+ Y+ + +++G K + +DH + ++ D+Y PR ++ S+ + + + NE V+LG+ ++ +++ + +G + L P ++ P G K+ +I+S I Y+ V I I + I +++L EL E QD L ++ ++ +W PE+LP + S++ + V Y +L +W + E +++ L + D+ +R AV++L T+ LY + Q ++AL++E Y + L+ F+L+ + + + +W L+ + + ++ + +A+ + + + N T I+ Q + +L I L+++ D + L L+ L D V + + + +E C V S +P+ + + ++ +SI I K DD+RQD +++L+ D IWK D++++ + + G G+ E V + T+M IQ+ + + +N L +W+ +N + +A E F RSCAG+ + T++LGI DRH DNI+ G +FHIDFG + + + G R+RVPFV T + I +G ++N+ F+ C KA+ LR + + + L IM S +P + + L ++ L ++ SD A + +
Sbjct: 569 LELYCR-----CTVSRYNIPPLQIITKPKVEVLSKMDFLQIMLNSVHSIPEHWQSQYSEFYMSLDLYHGTQVLDGFSNKVPKTIKNDH--FFPRIPLDLYAKFKRLNLCQYPRETRIVVSISGTVRNSAQAANEYNPDIVMLGYCSVPLYDENLFMRQGPLFL---PLTLLKKQPMLKPFGPYPYIKDARDPILIMSFKIWDTEIYFPN---VVIDMQCIPQDFATLD-IETQEYLLELIENQDTSTLETDDQDLIWQKRLHLTNQPEALPLVLSSLQDWSFGFVMRVYQILEEWAPLRPEIAMEFLLPKYPDERIRAHAVQSLARGSTDF---LYHTIPQFIEALRFELYEKSALADFILELSFVSLDFTFEIYWQLQQRVDHCAVDDLPYAIRCQNLQQKMIDEHENPNLKTDIKLQHELLNELDSIQDDLRSKSGDSEIERLHRLRTRLGILDSKLLQNKVRLPICPAFDCTGVRIEECSVFNSNAKPLKIVFRGLNM--NYSI-----IHKRDDDMRQDAFVMKMLNEMDRIWKSNGLDLRMITFRIMPVGYRRGMGELVLNCATLMEIQKEEGLRGV-LNDEILRKWLMKHNSDEFAYKEAQENFIRSCAGWCIVTYVLGIGDRHNDNILFTKNGHVFHIDFGKYMGDWQMAAGFRRDRVPFVFTTEMFHVINNGR----APTQYNQKFIDYCCKAFNHLRRNKNTLTNLLRIMACSDIPGIN-MDSLAFVENNLMLDLSDTDATVQF 1291
BLAST of pi3k-like protein vs. Ensembl Celegans
Match: vps-34 (Phosphatidylinositol 3-kinase catalytic subunit type 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9TXI7]) HSP 1 Score: 166.007 bits (419), Expect = 2.225e-42 Identity = 147/548 (26.82%), Postives = 248/548 (45.26%), Query Frame = 3
Query: 1731 PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYES-----------------------------------------------YYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN------ESIKIYFAL---MLEAFCRGYLNFMTV--IRPQSIGIEKLVEISRILKAQREDLQLSTLKEY---LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWE--------NADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLR--KTLSVE-SDEKAALNYFNR 3158
P++L + +S+ W + EV +L++ W I E +L+LLS F +R ++V L + + LYL QLVQALKYE DL+ FL+ AL + ++ +W LK+E+ + E K+Y + ++EA + V + Q I +E L+ + KA+ L S E+ L K V L+ S + ++I +T KS+ P + ++ + +I E+++ IFK GDDLRQD L Q++ + D I K+ D+KL PY L+TG G ++ +K +K + +IQ M ++ + ++ + ++ + RS AGYSV +ILG+ DRH DN+++ G+LFH+DFG IL K LT + ++ + + S +F EF+ AY LR HS+++L L+S+M+D+G+P++ D + + L ++ SDE A + F +
Sbjct: 96 PKALNKYLRSVNWVHPQEVKTALALMNDWELIEAEDALELLSSAFTHPAVRAYSVSRLLEAASPEQVLLYLPQLVQALKYEQGQQLPEEGNPVPVVSEEEGKIPSVATTPTEELEGRDMTVVTKKEARKAASGDLATFLIDYALASPKVSNYLYWHLKTEIESTKESKEEHSKMYQNIQDRLMEALVKRPDTRAQVDSLHQQQIFVEDLIILMNEAKARGGRLNESKSAEFRTMLSRAKHMLDLKGVHLPLDPSFRLSSVIPDTASFFKSEMMPAKISFKVLQPNGKADRNIPEEYTV-----IFKTGDDLRQDQLIQQMVRLIDIILKKGQLDLKLTPYLVLSTGVGQGFVQCIK-SKPLRAIQEQYKAHKMDCIREAM-KELRPGDGPFGIEPNVIDNYVRSLAGYSVIMYILGLGDRHLDNLLLCENGKLFHVDFGFILGRDPKPMPPP-----MKLTSEMVQVMGG-----VKSKQFLEFVQHVDSAYRILRRHSNVLLNLFSLMLDAGIPDIAAEPDKAIFKIEQRLRLDLSDEAATKHIFTQ 626
BLAST of pi3k-like protein vs. Ensembl Celegans
Match: vps-34 (Phosphatidylinositol 3-kinase catalytic subunit type 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9TXI7]) HSP 1 Score: 166.777 bits (421), Expect = 7.685e-42 Identity = 147/548 (26.82%), Postives = 248/548 (45.26%), Query Frame = 3
Query: 1731 PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYES-----------------------------------------------YYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN------ESIKIYFAL---MLEAFCRGYLNFMTV--IRPQSIGIEKLVEISRILKAQREDLQLSTLKEY---LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWE--------NADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLR--KTLSVE-SDEKAALNYFNR 3158
P++L + +S+ W + EV +L++ W I E +L+LLS F +R ++V L + + LYL QLVQALKYE DL+ FL+ AL + ++ +W LK+E+ + E K+Y + ++EA + V + Q I +E L+ + KA+ L S E+ L K V L+ S + ++I +T KS+ P + ++ + +I E+++ IFK GDDLRQD L Q++ + D I K+ D+KL PY L+TG G ++ +K +K + +IQ M ++ + ++ + ++ + RS AGYSV +ILG+ DRH DN+++ G+LFH+DFG IL K LT + ++ + + S +F EF+ AY LR HS+++L L+S+M+D+G+P++ D + + L ++ SDE A + F +
Sbjct: 347 PKALNKYLRSVNWVHPQEVKTALALMNDWELIEAEDALELLSSAFTHPAVRAYSVSRLLEAASPEQVLLYLPQLVQALKYEQGQQLPEEGNPVPVVSEEEGKIPSVATTPTEELEGRDMTVVTKKEARKAASGDLATFLIDYALASPKVSNYLYWHLKTEIESTKESKEEHSKMYQNIQDRLMEALVKRPDTRAQVDSLHQQQIFVEDLIILMNEAKARGGRLNESKSAEFRTMLSRAKHMLDLKGVHLPLDPSFRLSSVIPDTASFFKSEMMPAKISFKVLQPNGKADRNIPEEYTV-----IFKTGDDLRQDQLIQQMVRLIDIILKKGQLDLKLTPYLVLSTGVGQGFVQCIK-SKPLRAIQEQYKAHKMDCIREAM-KELRPGDGPFGIEPNVIDNYVRSLAGYSVIMYILGLGDRHLDNLLLCENGKLFHVDFGFILGRDPKPMPPP-----MKLTSEMVQVMGG-----VKSKQFLEFVQHVDSAYRILRRHSNVLLNLFSLMLDAGIPDIAAEPDKAIFKIEQRLRLDLSDEAATKHIFTQ 877
BLAST of pi3k-like protein vs. Ensembl Celegans
Match: vps-34 (Phosphatidylinositol 3-kinase catalytic subunit type 3 [Source:UniProtKB/Swiss-Prot;Acc:Q9TXI7]) HSP 1 Score: 166.392 bits (420), Expect = 8.184e-42 Identity = 147/548 (26.82%), Postives = 248/548 (45.26%), Query Frame = 3
Query: 1731 PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYES-----------------------------------------------YYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN------ESIKIYFAL---MLEAFCRGYLNFMTV--IRPQSIGIEKLVEISRILKAQREDLQLSTLKEY---LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWE--------NADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLR--KTLSVE-SDEKAALNYFNR 3158
P++L + +S+ W + EV +L++ W I E +L+LLS F +R ++V L + + LYL QLVQALKYE DL+ FL+ AL + ++ +W LK+E+ + E K+Y + ++EA + V + Q I +E L+ + KA+ L S E+ L K V L+ S + ++I +T KS+ P + ++ + +I E+++ IFK GDDLRQD L Q++ + D I K+ D+KL PY L+TG G ++ +K +K + +IQ M ++ + ++ + ++ + RS AGYSV +ILG+ DRH DN+++ G+LFH+DFG IL K LT + ++ + + S +F EF+ AY LR HS+++L L+S+M+D+G+P++ D + + L ++ SDE A + F +
Sbjct: 343 PKALNKYLRSVNWVHPQEVKTALALMNDWELIEAEDALELLSSAFTHPAVRAYSVSRLLEAASPEQVLLYLPQLVQALKYEQGQQLPEEGNPVPVVSEEEGKIPSVATTPTEELEGRDMTVVTKKEARKAASGDLATFLIDYALASPKVSNYLYWHLKTEIESTKESKEEHSKMYQNIQDRLMEALVKRPDTRAQVDSLHQQQIFVEDLIILMNEAKARGGRLNESKSAEFRTMLSRAKHMLDLKGVHLPLDPSFRLSSVIPDTASFFKSEMMPAKISFKVLQPNGKADRNIPEEYTV-----IFKTGDDLRQDQLIQQMVRLIDIILKKGQLDLKLTPYLVLSTGVGQGFVQCIK-SKPLRAIQEQYKAHKMDCIREAM-KELRPGDGPFGIEPNVIDNYVRSLAGYSVIMYILGLGDRHLDNLLLCENGKLFHVDFGFILGRDPKPMPPP-----MKLTSEMVQVMGG-----VKSKQFLEFVQHVDSAYRILRRHSNVLLNLFSLMLDAGIPDIAAEPDKAIFKIEQRLRLDLSDEAATKHIFTQ 873
BLAST of pi3k-like protein vs. Ensembl Fly
Match: Pi3K92E (gene:FBgn0015279 transcript:FBtr0083940) HSP 1 Score: 416.001 bits (1068), Expect = 3.738e-127 Identity = 262/728 (35.99%), Postives = 401/728 (55.08%), Query Frame = 3
Query: 1188 KLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEK--------LNFDIYYSNIPRNAKLCFSLIEKTERGG-----------------NEVLLGWANINIFNYFGKLIEGSIDLNLWPF-EKIQDNGYFNPGGSTDSYKNRNS------VILSINISKVNY--------YYQEQSPV----RIMGSPISTTIQRIKAIIDR----DWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNII--AAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADG-SDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
K+ V V +++G A S+D P N ++FDI N+PR +LC + E T+ N+ L W N IF++ L G L W + + IQ F+P G+ + + LS V Y Y ++ V R + P I+ +K ++ D +YE+ +QD + + + L +PE L L + W +V + LL +WP I++E SL+LL + D +R+FA++ L L + D+ LYLLQLVQA+K+ESY +DL VFLL+ ALRN+++G FFW L+SEM S++ F L+LE + +G + + +R Q +EKL + S I K ++ + L+++L++ + +N+ + LN S + + + C V SK RP+++ +ENAD+ + + IFK GDDLRQD+LTLQ+L + D +WKR D ++ Y C++ K G+IE V+ A+T+ +IQ+ + A SL W++ +N+ ++ KA+ FT SCAGY VAT++LG+ DRH DNIMV GQLFHIDFGHIL + K+K GV RERVPFVLT DF+ I G +DR +S +F F LC +A+L LR+H LIL+L+S+MI +GLPEL+ +DL+YLR+TL ++ E+ A +F +F +A +W T ++W SH
Sbjct: 367 KVGVHVCLYHGDKKLCAQR------STDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYADDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRLQRQLAGP-EKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLH-FLKDEDLLLYLLQLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLKGCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNPSFRCSGVTPDRCKVMDSKMRPLWVVFENADV----NASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRERVPFVLTHDFVYVINKGFNDR--ESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASH 1080
BLAST of pi3k-like protein vs. Ensembl Fly
Match: Pi3K92E (gene:FBgn0015279 transcript:FBtr0083941) HSP 1 Score: 416.001 bits (1068), Expect = 3.738e-127 Identity = 262/728 (35.99%), Postives = 401/728 (55.08%), Query Frame = 3
Query: 1188 KLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEK--------LNFDIYYSNIPRNAKLCFSLIEKTERGG-----------------NEVLLGWANINIFNYFGKLIEGSIDLNLWPF-EKIQDNGYFNPGGSTDSYKNRNS------VILSINISKVNY--------YYQEQSPV----RIMGSPISTTIQRIKAIIDR----DWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNII--AAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADG-SDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
K+ V V +++G A S+D P N ++FDI N+PR +LC + E T+ N+ L W N IF++ L G L W + + IQ F+P G+ + + LS V Y Y ++ V R + P I+ +K ++ D +YE+ +QD + + + L +PE L L + W +V + LL +WP I++E SL+LL + D +R+FA++ L L + D+ LYLLQLVQA+K+ESY +DL VFLL+ ALRN+++G FFW L+SEM S++ F L+LE + +G + + +R Q +EKL + S I K ++ + L+++L++ + +N+ + LN S + + + C V SK RP+++ +ENAD+ + + IFK GDDLRQD+LTLQ+L + D +WKR D ++ Y C++ K G+IE V+ A+T+ +IQ+ + A SL W++ +N+ ++ KA+ FT SCAGY VAT++LG+ DRH DNIMV GQLFHIDFGHIL + K+K GV RERVPFVLT DF+ I G +DR +S +F F LC +A+L LR+H LIL+L+S+MI +GLPEL+ +DL+YLR+TL ++ E+ A +F +F +A +W T ++W SH
Sbjct: 367 KVGVHVCLYHGDKKLCAQR------STDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYADDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRLQRQLAGP-EKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLH-FLKDEDLLLYLLQLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLKGCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNPSFRCSGVTPDRCKVMDSKMRPLWVVFENADV----NASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRERVPFVLTHDFVYVINKGFNDR--ESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASH 1080
BLAST of pi3k-like protein vs. Ensembl Fly
Match: Pi3K92E (gene:FBgn0015279 transcript:FBtr0334643) HSP 1 Score: 416.001 bits (1068), Expect = 3.738e-127 Identity = 262/728 (35.99%), Postives = 401/728 (55.08%), Query Frame = 3
Query: 1188 KLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEK--------LNFDIYYSNIPRNAKLCFSLIEKTERGG-----------------NEVLLGWANINIFNYFGKLIEGSIDLNLWPF-EKIQDNGYFNPGGSTDSYKNRNS------VILSINISKVNY--------YYQEQSPV----RIMGSPISTTIQRIKAIIDR----DWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNII--AAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADG-SDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
K+ V V +++G A S+D P N ++FDI N+PR +LC + E T+ N+ L W N IF++ L G L W + + IQ F+P G+ + + LS V Y Y ++ V R + P I+ +K ++ D +YE+ +QD + + + L +PE L L + W +V + LL +WP I++E SL+LL + D +R+FA++ L L + D+ LYLLQLVQA+K+ESY +DL VFLL+ ALRN+++G FFW L+SEM S++ F L+LE + +G + + +R Q +EKL + S I K ++ + L+++L++ + +N+ + LN S + + + C V SK RP+++ +ENAD+ + + IFK GDDLRQD+LTLQ+L + D +WKR D ++ Y C++ K G+IE V+ A+T+ +IQ+ + A SL W++ +N+ ++ KA+ FT SCAGY VAT++LG+ DRH DNIMV GQLFHIDFGHIL + K+K GV RERVPFVLT DF+ I G +DR +S +F F LC +A+L LR+H LIL+L+S+MI +GLPEL+ +DL+YLR+TL ++ E+ A +F +F +A +W T ++W SH
Sbjct: 367 KVGVHVCLYHGDKKLCAQR------STDSPNGNFDTFLFNDLVMDFDIQMRNLPRMTRLCIVIFEVTKMSRSKKSSNNKDIALKDVPYNKNPLAWVNTTIFDHKDILRTGRHTLYTWTYADDIQSVEVFHPLGTIEPNPRKEECALVDLTFLSSGTGTVRYPSEEVVLQYAADREQVNRLQRQLAGP-EKPIKELKELMANYTGLDKIYEMVDQDRNAIWERRNDILRELPEELSILLHCVYWKERDDVADMWYLLKQWPLISIERSLELLDYAYPDPAVRRFAIRCLH-FLKDEDLLLYLLQLVQAIKHESYLESDLVVFLLERALRNQRIGHYFFWHLRSEMQTPSMQTRFGLLLEVYLKGCKHHVAPLRKQLHVLEKLKQGSLIAKKGSKEKVKTMLQDFLRDQRNSAVFQNIQNPLNPSFRCSGVTPDRCKVMDSKMRPLWVVFENADV----NASDVHIIFKNGDDLRQDMLTLQMLRVMDQLWKRDGMDFRMNIYNCISMEKSLGMIEVVRHAETIANIQKEKGMFSATSPFKKGSLLSWLKEHNKPADKLNKAINEFTLSCAGYCVATYVLGVADRHSDNIMVKRNGQLFHIDFGHILGHFKEKLGVRRERVPFVLTHDFVYVINKGFNDR--ESKEFCHFQELCERAFLVLRKHGCLILSLFSMMISTGLPELSSEKDLDYLRETLVLDYTEEKAREHFRAKFSEALANSWKTSLNWASH 1080
BLAST of pi3k-like protein vs. Ensembl Fly
Match: Pi3K68D (gene:FBgn0015278 transcript:FBtr0076087) HSP 1 Score: 222.631 bits (566), Expect = 9.322e-59 Identity = 185/692 (26.73%), Postives = 324/692 (46.82%), Query Frame = 3
Query: 1293 LNFDIY-YSNIPRNAKLCFSLIEKT-------------ERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRN-SVILSINI----SKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYEL-SEQDIDYL-RSNLENCLW--------VPESLPR-LAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLE--------AFCRGYLNFMTVIRP-QSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVE-TCDVKKSKKRPIYLEWENADIFSEFSIP-----------TLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
L FD + +PR A+L F L K ER LGW +I +F++ +I G L+LWP + P + + + +LSI + ++ + ++ P A +D + EL ++ Y + W P +LP+ L + W+ ++L ++LL W ++ SL+LL + D +R+ AV+ + + + N + +L QLVQ+LK+++Y + ++ FLL L + + +W L + ++ A M++ R Y ++R +I EK+++ R + R +L+T+ E +K + E+ + S + E +++ + TC + + N F+ ++P +L IFKCGDDL+QD LT+QL+ I + +W + D+K++ + C+ TG SG+IE V +A+T+ IQ + + W+ N + ++ A+ FT SCAGYSVAT++LGI DRH DNIM+ T G LFHIDFG L + + R+R PFVLT D I +G D+P S F+ F+ LC +A+ +R+++ L+L + M +G+P + ++Y+R+ L A F + + + +W T+ ++ H
Sbjct: 911 LTFDQHPICTLPREARLTFVLYGKQAASEGEPNADQNGERRQVTTELGWCSIQLFDFKRVMICGPYLLSLWP---PMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGRIEFPEHQEVP--------KPAPHYDFASLDANLQEELLDTAELGYTGATERREVFWEKRLYLQSYPNALPKVLHAAHSWDYANLIDL-HALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEWI-SKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPDDPHNSIGAAMVDQEYDESQVTQVRYYRRNKMMLRALMAICGEKMLQ--RFMYQHRMCQKLTTIAESVK--EAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSNTLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPTGYKSGMIELVSEAETLRKIQVECGLTG-SFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCAGYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRDRTPFVLTSDMAYVI-NGGDKP--STDFHYFVDLCCRAFNIVRKNADLLLHTLAHMATAGMPGVNS-NAVQYVRRALLPSQSNPEAAATFAKMIQSSLK-SWFTQFNFFLH 1579
BLAST of pi3k-like protein vs. Ensembl Fly
Match: Pi3K68D (gene:FBgn0015278 transcript:FBtr0301816) HSP 1 Score: 222.631 bits (566), Expect = 9.322e-59 Identity = 185/692 (26.73%), Postives = 324/692 (46.82%), Query Frame = 3
Query: 1293 LNFDIY-YSNIPRNAKLCFSLIEKT-------------ERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRN-SVILSINI----SKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYEL-SEQDIDYL-RSNLENCLW--------VPESLPR-LAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLE--------AFCRGYLNFMTVIRP-QSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVE-TCDVKKSKKRPIYLEWENADIFSEFSIP-----------TLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
L FD + +PR A+L F L K ER LGW +I +F++ +I G L+LWP + P + + + +LSI + ++ + ++ P A +D + EL ++ Y + W P +LP+ L + W+ ++L ++LL W ++ SL+LL + D +R+ AV+ + + + N + +L QLVQ+LK+++Y + ++ FLL L + + +W L + ++ A M++ R Y ++R +I EK+++ R + R +L+T+ E +K + E+ + S + E +++ + TC + + N F+ ++P +L IFKCGDDL+QD LT+QL+ I + +W + D+K++ + C+ TG SG+IE V +A+T+ IQ + + W+ N + ++ A+ FT SCAGYSVAT++LGI DRH DNIM+ T G LFHIDFG L + + R+R PFVLT D I +G D+P S F+ F+ LC +A+ +R+++ L+L + M +G+P + ++Y+R+ L A F + + + +W T+ ++ H
Sbjct: 911 LTFDQHPICTLPREARLTFVLYGKQAASEGEPNADQNGERRQVTTELGWCSIQLFDFKRVMICGPYLLSLWP---PMTDKMLGPAPARGCHPQPDFCPVLSIEVPPYGGRIEFPEHQEVP--------KPAPHYDFASLDANLQEELLDTAELGYTGATERREVFWEKRLYLQSYPNALPKVLHAAHSWDYANLIDL-HALLHSWAPLSPLQSLELLLPRYPDAKVREKAVEWI-SKMPNDQLVDFLPQLVQSLKHDTYEGSAMARFLLSKCLESPRFAHHMYWLLVHSLPDDPHNSIGAAMVDQEYDESQVTQVRYYRRNKMMLRALMAICGEKMLQ--RFMYQHRMCQKLTTIAESVK--EAKESMRQKSLAAGMDEVHQDLLEQPTCLPLGPELEVTGVSVRNCSYFNSNTLPLKINFVGPDAESLPAIFKCGDDLQQDQLTIQLIRIMNKMWLAERLDLKMVTFNCVPTGYKSGMIELVSEAETLRKIQVECGLTG-SFKDRPIAEWLGKQNPSPLEYQSAVRNFTLSCAGYSVATYVLGICDRHNDNIMLKTSGHLFHIDFGKFLGDAQMFGNFKRDRTPFVLTSDMAYVI-NGGDKP--STDFHYFVDLCCRAFNIVRKNADLLLHTLAHMATAGMPGVNS-NAVQYVRRALLPSQSNPEAAATFAKMIQSSLK-SWFTQFNFFLH 1579
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Match: zgc:158659 (zgc:158659 [Source:ZFIN;Acc:ZDB-GENE-070112-492]) HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0 Identity = 379/1053 (35.99%), Postives = 578/1053 (54.89%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKK---EHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLL----ISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVN---YYYQEQ--------SPVRIMG--------------SPISTT-IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LPN + R+A L IK L E + +Y LL S YIF GV ++AE EE+YDE++ LC+L L +L +E GN +E ++N IGF + E+ + D E+ + R++ L V ++ E E A+ + ++ + + L + +I S + K + I+ + ++ I + + K S + + E +Y+LKV D Y L + Y Y++SC+ P L L ++ L + + + P + + PQ SL + +L+C ++ K+YVR +++G + + V +P WNE L++DIY +++PR+A+LC S+ K +G E L W NIN+F+Y L+ G + L LWP ++ NP G + S N+ + + + N + EQ S R +G S IS ++++ + RD LYELSEQ+ D+L + C+ +PESLP+L S++WN+ EV+ Y LL WP + ESSL+LL NF D ++R+FA++ L LT+ ++ YLLQLVQ LKYE Y N L+ FL++ AL N+++G FFW LKSEMHN+++ F L+LEAFCR ++ + Q ++KLV ++ LK +++D Q+ L E++ D+ E + S LN + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE VK++ T+M IQ + + A+Q NS++L+ WI+ N+ E + +A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + +F F +C KAYL +R+H+SL + L+S+++ G+PEL D+ YLRKTL++E ++ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCCLPNGILVSLECLREAPLTSIKQQLFSEARKYPLYH--LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEK----ILNREIGFAIGMPICEFELVKDPEVQDFRRNILSVCREAVEEREGGGAHTQALYVYPPNVESSPDLPQHIYSKLDKGRLIVTIWVIVSPSNSKQKYTLKIAHDSLPEQLIAEAIRKKTRSMHLS-AQQLRLCVQEYQGQYILKVCGCDEYFLEKY-PLSQYKYIRSCITLCRLPHLMLVSKDSLYSQLPSSGFMAPSYSRRTPQPSPCPGGGDPGSPRSLWAFNTHLRVRLLCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLSYDIYLTDVPRSARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYKDTLVSGKVALGLWPVPHGLED-LLNPIGVSGSNPNKETPCVELEFPWFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESSLELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDRNKG-EAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha [Source:ZFIN;Acc:ZDB-GENE-130409-1]) HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0 Identity = 373/1059 (35.22%), Postives = 583/1059 (55.05%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E A+ + ++ Y + E + + I L + + +I + + K + I+ + ++ I + + K S + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ T I++++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + +N +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS++L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDASGAHSRALYVYPPNV-ESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAE-QLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKG-EMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha [Source:ZFIN;Acc:ZDB-GENE-130409-1]) HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0 Identity = 373/1059 (35.22%), Postives = 583/1059 (55.05%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E A+ + ++ Y + E + + I L + + +I + + K + I+ + ++ I + + K S + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ T I++++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + +N +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS++L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDASGAHSRALYVYPPNV-ESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAE-QLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKG-EMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha [Source:ZFIN;Acc:ZDB-GENE-130409-1]) HSP 1 Score: 605.134 bits (1559), Expect = 0.000e+0 Identity = 373/1059 (35.22%), Postives = 583/1059 (55.05%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E A+ + ++ Y + E + + I L + + +I + + K + I+ + ++ I + + K S + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ T I++++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + +N +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS++L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDASGAHSRALYVYPPNV-ESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAE-QLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKG-EMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Match: zgc:158659 (zgc:158659 [Source:ZFIN;Acc:ZDB-GENE-070112-492]) HSP 1 Score: 510.375 bits (1313), Expect = 4.325e-168 Identity = 269/626 (42.97%), Postives = 389/626 (62.14%), Query Frame = 3
Query: 1431 LIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVN---YYYQEQ--------SPVRIMG--------------SPISTT-IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
L+ G + L LWP ++ NP G + S N+ + + + N + EQ S R +G S IS ++++ + RD LYELSEQ+ D+L + C+ +PESLP+L S++WN+ EV+ Y LL WP + ESSL+LL NF D ++R+FA++ L LT+ ++ YLLQLVQ LKYE Y N L+ FL++ AL N+++G FFW LKSEMHN+++ F L+LEAFCR ++ + Q ++KLV ++ LK +++D Q+ L E++ D+ E + S LN + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE VK++ T+M IQ + + A+Q NS++L+ WI+ N+ E + +A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + +F F +C KAYL +R+H+SL + L+S+++ G+PEL D+ YLRKTL++E ++ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 3 LVSGKVALGLWPVPHGLED-LLNPIGVSGSNPNKETPCVELEFPWFNQTVVFPDEQQIEEHANWSISRELGYSYCLGLSSRLACDSSISQADAEQLRTLCSRDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLSVKWNSRDEVSQIYCLLKDWPLMQPESSLELLDCNFPDPMVREFALRCLIQGLTDDKLSQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKQEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSHTIMQIQCKGGLKGALQFNSNTLHHWIRDRNKG-EAYDRAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGVQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFH 626
BLAST of pi3k-like protein vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:100144924]) HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0 Identity = 379/1053 (35.99%), Postives = 583/1053 (55.37%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNYY-------YQEQSPVRIMG-----SPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN V R+A+L IK L KE + +Y LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + RK+ L V K E AN P ++ Y + E ++ + I L + + +I + K + I+ + V E + + KK S + E KY+LKV L + Y Y++SC+ P L L ++ L I ++ F +P Y + + S ++++ + +++C ++ K+YVR +++G+ + + V +P WNE L +D++ ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G + S N+ + L + S V + + + R MG S +S I R +KAI +RD L E++EQ+ ++L S+ C +PE LP+L S++WN +V+ Y LL +WP I E +++LL N+ D+++R FAV L LT+ ++ YL+QLVQ +KYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E +K DF + + +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREE----KILNREIGFAIGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNV-ESSSELPKHIESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHD-CVPEHVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVDVFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGIYHGVEP-LCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVSGSNPNKETPCLELEFDCFSSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPLSEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAMELLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-ETYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGIQECTKTRDFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Xenopus
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:100144924]) HSP 1 Score: 512.686 bits (1319), Expect = 2.457e-164 Identity = 339/960 (35.31%), Postives = 522/960 (54.37%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNYY-------YQEQSPVRIMG-----SPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADG 2936
+ V LLPN V R+A+L IK L KE + +Y LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + RK+ L V K E AN P ++ Y + E ++ + I L + + +I + K + I+ + V E + + KK S + E KY+LKV L + Y Y++SC+ P L L ++ L I ++ F +P Y + + S ++++ + +++C ++ K+YVR +++G+ + + V +P WNE L +D++ ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G + S N+ + L + S V + + + R MG S +S I R +KAI +RD L E++EQ+ ++L S+ C +PE LP+L S++WN +V+ Y LL +WP I E +++LL N+ D+++R FAV L LT+ ++ YL+QLVQ +KYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E +K DF + + +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G
Sbjct: 20 ILVECLLPNGMVVVLECLREATLVNIKHELFKEARKYPLYH--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVVEPVGNREE----KILNREIGFAIGMPVCEFDMVKDSEVQDFRKNILNVCKDSVELRDANGPISRALYVYPPNV-ESSSELPKHIESKLDKGQIIVVIWVIVSPNNEKQKYSLKINHD-CVPEHVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKDSLYSQIPVDVFTMPSYSRRISTAAPYMNGEASAKSLWAINSTLRIKILCATYVNVNIRDIDKIYVRTGIYHGVEP-LCDNVNTQRVPCSNPRWNEWLLYDMFIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVSGSNPNKETPCLELEFDCFSSPVKFPDMTAIEDHANKVLEREMGYNYSHSGLSNRIVRENEVRESDKEQLKAISNRDPLSEITEQEKEFLWSHRLYCRNIPEILPKLLLSVKWNCRDDVSQMYCLLKEWPAIRPEQAMELLDFNYPDRIVRSFAVSCLEKYLTDDKLSQYLIQLVQVMKYEQYLDNHLVRFLLKKALVNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSKQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMKRPDFMDALQGFTSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSEMLFLNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRCSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-ETYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDNGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG 967
BLAST of pi3k-like protein vs. Ensembl Xenopus
Match: slc27a6 (solute carrier family 27 member 6 [Source:Xenbase;Acc:XB-GENE-491992]) HSP 1 Score: 456.447 bits (1173), Expect = 1.177e-142 Identity = 281/794 (35.39%), Postives = 439/794 (55.29%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL-----------------IEKTERGGNEVLL--------GWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSI---NISKVNYYYQEQSPVRIM---GSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY------LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P L+L +E +I + F Q + + + R+ S M L + + + + VR +F+G P + + WNE L F+I ++PR A+LCF++ I+K+ +EVLL W N +F+Y G+L G L+ W + NP G+ T+ Y N+ L I + SK Y V ++ G +K I++RD L +L E + D + + +C P SLP+L S++WN + +V +LL W ++ +L+LL N+ D+ +R++AV L+ +++ +++ YLLQLVQ LKYE + LS FLLQ AL N+++GQ FW L+SE+HN ++ + F L+LEA+CRG + M V+ Q + KL ++ ++K ++LS +K L+ + + E ++ S LN S ++VE C SK +P+++ + N S+ +L IFK GDDLRQD+L LQLL + D +WK D++++PYGCLATG G IE V A+T+ IQ SN+ AA N +L WI+ + + + +A+E FT SCAGY VAT++LGI DRH DNIMV GQLFHIDFGHIL N K KF + RER PF+LT DFI I G +P ++ KF F C AYL LR + +LI+TL+++M+ +GLPEL+ V+D++Y++ +L++ E+ AL F ++F +A + +WTTK++W++H
Sbjct: 255 LIQFQYIRNCVMNKALPHLTL-----VECCNIKKL-----FDQEMSEIEHAVRRKS--SMHPALPMP---LPPKKRGVLVRAGLFHGTELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQTIKKSALCCSEVLLCFTQHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPY-TENTTTLHIKFHDYSKEPISYPPFDKVNLLVRHGECGKKLNIELKEIMERDPLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVNCLKP-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALDNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGLIKLNA--VKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKPLWIVYNNRGFGSD----SLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATGDRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECH-SGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQG--KPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAH 1022
BLAST of pi3k-like protein vs. Ensembl Xenopus
Match: slc27a6 (solute carrier family 27 member 6 [Source:Xenbase;Acc:XB-GENE-491992]) HSP 1 Score: 455.292 bits (1170), Expect = 5.472e-142 Identity = 278/800 (34.75%), Postives = 439/800 (54.87%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFPILSL---------YPREY--LENISINRFIIPPYFYQNIPQTKRRTRQDS---------VSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTER---------------GGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINISKVNYYYQE--QSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY------LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P L+L + +E +E+ + + P +P KR + + + + ++L + E+S L VR +F+G P + + WNE L F+I ++PR A+LCF++ ++ G + W N +F+Y G+L G L+ W + NP G+ T+ Y N+ L I K + Y +E P G +K I++RD L +L E + D + + +C P SLP+L S++WN + +V +LL W ++ +L+LL N+ D+ +R++AV L+ +++ +++ YLLQLVQ LKYE + LS FLLQ AL N+++GQ FW L+SE+HN ++ + F L+LEA+CRG + M V+ Q + KL ++ ++K ++LS +K L+ + + E ++ S LN S ++VE C SK +P+++ + N S+ +L IFK GDDLRQD+L LQLL + D +WK D++++PYGCLATG G IE V A+T+ IQ SN+ AA N +L WI+ + + + +A+E FT SCAGY VAT++LGI DRH DNIMV GQLFHIDFGHIL N K KF + RER PF+LT DFI I G +P ++ KF F C AYL LR + +LI+TL+++M+ +GLPEL+ V+D++Y++ +L++ E+ AL F ++F +A + +WTTK++W++H
Sbjct: 255 LIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKSSMHPALPMPLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVL-VRAGLFHGTELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQTIKKSGKMHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPY-TENTTTLHI---KFHDYSKEPISYPPFDKGRGGKKLNIELKEIMERDPLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVNCLKP-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALDNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGLIKLNA--VKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKPLWIVYNNRGFGSD----SLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATGDRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECH-SGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQG--KPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAH 1039
BLAST of pi3k-like protein vs. Ensembl Xenopus
Match: slc27a6 (solute carrier family 27 member 6 [Source:Xenbase;Acc:XB-GENE-491992]) HSP 1 Score: 451.825 bits (1161), Expect = 1.849e-140 Identity = 278/815 (34.11%), Postives = 445/815 (54.60%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFPILSL---------YPREY--LENISINRFIIPPYFYQNIPQTKRRTRQDS---------VSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTER---------------GGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSI---NISKVNYYY-------QEQSPVRIMGSPISTTIQ-------RIKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY------LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P L+L + +E +E+ + + P +P KR + + + + ++L + E+S L VR +F+G P + + WNE L F+I ++PR A+LCF++ ++ G + W N +F+Y G+L G L+ W + NP G+ T+ Y N+ L I + SK Y ++ + + +ST+ + +K I++RD L +L E + D + + +C P SLP+L S++WN + +V +LL W ++ +L+LL N+ D+ +R++AV L+ +++ +++ YLLQLVQ LKYE + LS FLLQ AL N+++GQ FW L+SE+HN ++ + F L+LEA+CRG + M V+ Q + KL ++ ++K ++LS +K L+ + + E ++ S LN S ++VE C SK +P+++ + N S+ +L IFK GDDLRQD+L LQLL + D +WK D++++PYGCLATG G IE V A+T+ IQ SN+ AA N +L WI+ + + + +A+E FT SCAGY VAT++LGI DRH DNIMV GQLFHIDFGHIL N K KF + RER PF+LT DFI I G +P ++ KF F C AYL LR + +LI+TL+++M+ +GLPEL+ V+D++Y++ +L++ E+ AL F ++F +A + +WTTK++W++H
Sbjct: 261 LIQFQYIRNCVMNKALPHLTLVECCNIKKLFDQEMSEIEHAVRRKSSMHPALPMPLPPKKRGASMKTLNMRDIVWNIVQPYKIILSKGSRLNTEDSVL-VRAGLFHGTELLCKPTMTPEVQGKNDHVWNETLEFEINVCDLPRMARLCFAIYAVLDKPRNKNKTKYQTIKKSGKMHFPVAWVNTMVFDYKGQLRSGDHVLHCWSSFPDELEEMLNPMGTVRTNPY-TENTTTLHIKFHDYSKEPISYPPFDKILEKAAEIARNSDSLSTSGRGGKKLNIELKEIMERDPLCQLCENEKDLIWTLRYDCRENFPGSLPKLLLSVKWNKLEDVAQLQALLQIWSKLPPRDALELLDFNYPDQYVREYAVNCLKP-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLQRALDNRRIGQFLFWHLRSEVHNPAVSVQFGLLLEAYCRGSVAHMKVLSRQVEALNKLRTLNGLIKLNA--VKLSKVKNKDNMHTCLRENAYKEALMHIQSPLNPSITLSELVVEKCKYMDSKMKPLWIVYNNRGFGSD----SLGIIFKNGDDLRQDMLALQLLRLMDMLWKEAGLDLRIVPYGCLATGDRCGFIEVVSAAETIADIQLDSSNLAAAAAFNKDALLNWIKECH-SGDDLERAIEEFTLSCAGYCVATYVLGIGDRHNDNIMVRKTGQLFHIDFGHILGNFKSKFKIKRERGPFILTYDFIHVIQQG--KPGNTEKFGRFRQCCEDAYLILRRNGNLIITLFALMLTAGLPELSSVKDIQYVKDSLALGKKEEDALKQFRQKFDEALKESWTTKVNWMAH 1063
BLAST of pi3k-like protein vs. Ensembl Mouse
Match: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581]) HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0 Identity = 375/1054 (35.58%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L +E + +++ LL + +SYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + I+ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++A+ RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQ--LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Mouse
Match: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581]) HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0 Identity = 375/1054 (35.58%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L +E + +++ LL + +SYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + I+ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++A+ RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQ--LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Mouse
Match: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581]) HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0 Identity = 309/796 (38.82%), Postives = 466/796 (58.54%), Query Frame = 3
Query: 969 YDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
Y Y++SC+ P L L +E L + I+ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++A+ RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 148 YKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFH 938
BLAST of pi3k-like protein vs. Ensembl Mouse
Match: Pik3cb (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:MGI Symbol;Acc:MGI:1922019]) HSP 1 Score: 469.544 bits (1207), Expect = 2.427e-147 Identity = 289/815 (35.46%), Postives = 450/815 (55.21%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFP---------ILSLYPREYLE-NISINRFI--IPPYFYQNIPQTKRRTRQDSV----SKMFSLLLISA-QLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-------------------KTERGGNEV--LLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINIS---KVNYYYQ------EQSPVRIMGSPISTT-------IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P I +Y +E + +INR +P +P ++TR S + F + L+ +L +E K++VR +F+G S + + WNE+L FDI ++PR A+LCF++ +T R +V + W N +F++ G+L G + L+ W + NP G+ T+ Y N+ L I K YY E++ G + + + +K I+DRD L +L E ++D + + ++C P+SLP+L SI+WN + +V +LL WP++ +L+LL N+ D+ +R++AV LR +++ +++ YLLQLVQ LKYE + LS FLL+ AL N+++GQ FW L+SE+H ++ + F ++LEA+CRG + M V+ Q + KL ++ ++K L + KE LK + E ++ S LN + VE C SK +P++L + ++ F E S+ IFK GDDLRQD+LTLQ+L + D +WK D+++LPYGCLATG SG+IE V ++T+ IQ SN+ A N +L W++ N + + +A+E FT SCAGY VA+++LGI DRH DNIMV GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + ++ KF F C AYL LR H +L +TL+++M+ +GLPELT V+D++YL+ +L++ E+ AL F ++F +A R +WTTK++W++H
Sbjct: 257 LIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLP------LPLPPKKTRVISHIWDNNNPFQITLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYA-ENATALHITFPENKKQPCYYPPFDKIIEKAAELASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLSRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVY-SSRAFGEDSV---GVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYN-SGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG--KTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAH 1056
BLAST of pi3k-like protein vs. Ensembl Mouse
Match: Pik3cd (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [Source:MGI Symbol;Acc:MGI:1098211]) HSP 1 Score: 453.366 bits (1165), Expect = 2.041e-141 Identity = 261/727 (35.90%), Postives = 404/727 (55.57%), Query Frame = 3
Query: 1125 SVSKMFSLLLISAQLI-CKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL---IEKTERGGN--------EVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNS----VILSINISKVNYYYQEQSPVRIMG-----SPISTTIQRIKAIIDRDWLYELSEQDIDY---LRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYL----KNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
S+ + FS+ LI + + E KL V+ +F+G S + P W ++L FDI ++PR A+LCF+L +EK ++ + + + WAN+ +F+Y +L G L +WP + NP G+ N S VI ++ Y+ + +G I+ +++ I++R EL E + D +R ++ PE+L RL +WN +V LL WP + + S+L+LL +F D + FA+K+LR LT+ ++ YLLQLVQ LKYESY +L+ FLL AL N+++G FW L+SEMH S+ + F L++EA+CRG + M V+ Q + KL ++ +K + KE + + + + E ++ S L+ S + VE C SK +P+++ + + + S ++ IFK GDDLRQD+LTLQ++ + D +WK++ D+++ PYGCL TG +G+IE V + T+ +IQ +SN+ A N +L W+++ N E +A+E FT SCAGY VAT++LGI DRH DNIM+ GQLFHIDFGH L N K KFG+NRERVPF+LT DF+ I G +S KF F C +AY LR H L L L+++M +GLPEL+ +D++YL+ +L++ E+ AL +F +F +A R +W TK++WL+H
Sbjct: 318 SLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEMLCKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRITEEELQLREILERRGSGELYEHEKDLVWKMRHEVQEHF--PEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRK-LTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDSKMKPLWIMYSSEEAGSAGNV---GIIFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDALLNWLKSKN-PGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTN--NSEKFERFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFNEALRESWKTKVNWLAH 1035 HSP 2 Score: 60.8474 bits (146), Expect = 9.147e-9 Identity = 39/122 (31.97%), Postives = 63/122 (51.64%), Query Frame = 3
Query: 162 DVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNL 527
D P+ ++T S V V LLP F VSR A+L IK +L + ++ +L++ +Y+F VN+ AE +E DE + LC++ VL + R+G+ + + S I+ IG L
Sbjct: 6 DCPMEFWTKEESQSVVVDFLLPTGVYLNFPVSRNANLSTIKQVLWHRAQYEPLFH--MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLLIGKGL 125
BLAST of pi3k-like protein vs. UniProt/SwissProt
Match: sp|A0A0G2K344|PK3CA_RAT (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform OS=Rattus norvegicus OX=10116 GN=Pik3ca PE=1 SV=1) HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0 Identity = 377/1054 (35.77%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + +++ LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + I+ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++A+ RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQ--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETATKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. UniProt/SwissProt
Match: sp|P42336|PK3CA_HUMAN (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PIK3CA PE=1 SV=2) HSP 1 Score: 609.372 bits (1570), Expect = 0.000e+0 Identity = 378/1054 (35.86%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + +++ LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + ++ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R +KAI RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. UniProt/SwissProt
Match: sp|P32871|PK3CA_BOVIN (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform OS=Bos taurus OX=9913 GN=PIK3CA PE=1 SV=1) HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0 Identity = 377/1054 (35.77%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + +++ LL + SSYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + ++ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++AI RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQ--LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLRAICTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. UniProt/SwissProt
Match: sp|P42337|PK3CA_MOUSE (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform OS=Mus musculus OX=10090 GN=Pik3ca PE=1 SV=2) HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0 Identity = 375/1054 (35.58%), Postives = 577/1054 (54.74%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPY---FYQNIPQTKRRTRQDSVSKMFSLLLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----------------SKVNYYYQEQSPVRIMGSPISTTIQR-----------IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L +E + +++ LL + +SYIF V ++AE EE++DE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K+ + N P+ ++ Y + E + + I + I + S N K T+ V E + + KK S + E KY+LKV + Y Y++SC+ P L L +E L + I+ F +P Y P T S+ + S L I +++C ++ K+YVR +++G + + V +P WNE LN+DIY ++PR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + N+ ++ + +S + R ++A+ RD L E++EQ+ D+L S+ C+ +PE LP+L S++WN+ EV Y L+ WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ DF + + S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQ--LLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNV-ESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKV-CGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRI--KILCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKG-EIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGAQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. UniProt/SwissProt
Match: sp|Q9Z1L0|PK3CB_RAT (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Rattus norvegicus OX=10116 GN=Pik3cb PE=2 SV=1) HSP 1 Score: 476.093 bits (1224), Expect = 6.854e-149 Identity = 285/809 (35.23%), Postives = 443/809 (54.76%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFP---------ILSLYPREYLE-NISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISA-QLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-------------------KTERGGNEVL--LGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS--TDSYKNRNSVILSINIS---KVNYYYQEQSPVRIMGSPISTT-------------IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I + Y+++C+ N P I +Y +E + +INR +T+ + + F ++L+ +L +E K++VR +F+G S + + WNE+L FDI ++PR A+LCF++ +T R +V + W N +F++ G+L G + L+ W + NP G+ T+ Y N+ L I K YYY + + I++ + +K I+DRD L +L E ++D + + ++C P+SLP+L SI+WN + +V +LL WP++ +L+LL N+ D+ +R++AV LR +++ +++ YLLQLVQ LKYE + LS FLL+ AL N+++GQ FW L+SE+H ++ I F ++LEA+CRG + M V+ Q + KL ++ ++K L + KE LK + E ++ S LN + VE C SK +P++L + N F + IFK GDDLRQD+LTLQ+L + D +WK D+++LPYGCLATG SG+IE V ++T+ IQ SN+ A N +L W++ N + + +A+E FT SCAGY VA+++LGI DRH DNIMV GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + ++ KF F C AYL LR H +L +TL+++M+ +GLPELT V+D++YL+ +L++ E+ AL F ++F +A R +WTTK++W++H
Sbjct: 263 LIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAIEAAINRNSSSLPLPLPPKKTRVISHVWGNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDVILHSWSSFPDELEEMLNPMGTVQTNPYA-ENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASGDSANVSSRGGKKFLAVLKEILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQ-MSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALDNRRIGQFLFWHLRSEVHTPAVSIQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAMKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCRYMDSKMKPLWLVYSN----RAFGEDAVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYN-SGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQG--KTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAH 1062
BLAST of pi3k-like protein vs. TrEMBL
Match: D2DJU4 (Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 2027.68 bits (5252), Expect = 0.000e+0 Identity = 1017/1023 (99.41%), Postives = 1022/1023 (99.90%), Query Frame = 3
Query: 150 MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 3218
MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNS+YEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVI+HCIG NLDNLPKEYYELYDLELLNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVSSLDSYLLNLNDKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMF+LLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPIS+TIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVI+PQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF
Sbjct: 1 MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSVYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVISHCIGLNLDNLPKEYYELYDLELLNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVSSLDSYLLNLNDKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFTLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISSTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIKPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 1023
BLAST of pi3k-like protein vs. TrEMBL
Match: A0A222C681 (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 1582.77 bits (4097), Expect = 0.000e+0 Identity = 785/1026 (76.51%), Postives = 902/1026 (87.91%), Query Frame = 3
Query: 150 MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYE-ELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKV-NYYYQEQSPVRIMGSPISTTIQ-RIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 3218
M RS+VPLNYY+YSF N+V+VMILLPNFSVEEF VS+K SL+E+KDIL+KELKTN IYE E LNNFSSYIFCGVNR+AEIEEYYDESQLLCNLNL+DFVLNCLERKGN+ ESQLTSVINHCIG NLDN+PKE +L L ARKSYLEVV EHE+L+ N N+++++QYGADYNE+TT T RQILQSM+ LYIT++ISYK+ + FKC+++ISKE+TVK+TI KIL DKK+ FE+D + D +W+SEN+ KYVLK SSLDSYL+ +DK+I+Y+YVQSCLYNNEFPILSLYP YLENISI +F+IP YFYQN+PQ KR+ + D +K FS+ L AQLICKENSK+Y+R AMFNGINTRI EQKS+LV SDHP WNE LNFDI NIPRNAKLC SLIE+ ERG NE++LGW NINIFNY+G+LIEGS+DLNLW EK DNGYF+P GS S K ++I+ ++I K+ NYYYQE +RI SP+ IQ RIK IIDRD L ELSEQDIDYLR+NLENCLW+PESLPRLAKSIRWNN EVN FYSLLS WP+++LESSLQLL GNFFD++LR+FAV NLR+ILTNAD+NLYLLQL+QALKYESYYFNDL+++L+QSALR+KQLGQKFFWFLKSEMHN++IK+YFA++ EAFCRGY NF+ +IRPQ I IEKL+EIS ILK QR +LQLSTLK+YL+ND+FNE CKNV+SLL LSEKQGNIIV+TCDVKKSKKRPIYLEW+NADIFS+ PTLKFIFKCGDDLRQD+LTLQ+LSIFDWIWKRQFQDMKLLPYGCLA+GKDSGIIEAVKDAKTVMSIQRS++ +AMQM+S SLYRWI++NN TCEQF KALETFTRSCAGYSVATFILGIRDRHPDNIMVN+KGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFI TIA+G D+P S KFN+F VLCGKAYLKLREHSSLILTLYS+MIDSGLPELTKVQDLEYLRKTLSV+S E+ AL YFNRQF +AY GNWTTKIDWLSH+
Sbjct: 1 MIRSEVPLNYYSYSFLNNVSVMILLPNFSVEEFNVSKKVSLYELKDILMKELKTNPIYEKEYALNNFSSYIFCGVNREAEIEEYYDESQLLCNLNLMDFVLNCLERKGNKLESQLTSVINHCIGLNLDNIPKENDDLELLF---ARKSYLEVVHSEHENLLNNKNEVLLYQYGADYNEYTTLTIRQILQSMSNLYITSIISYKTTDKFKCIISISKEYTVKDTINKILYDKKECFEYDVNTDLRVWSSENASKYVLKFSSLDSYLIKPDDKLIYYEYVQSCLYNNEFPILSLYPISYLENISIIQFLIPSYFYQNMPQVKRKIQVDITNKYFSIFLKGAQLICKENSKIYIRAAMFNGINTRITSEQKSNLVPSDHPAWNETLNFDIECVNIPRNAKLCLSLIERNERGNNELVLGWRNINIFNYYGRLIEGSLDLNLWSCEKTPDNGYFHPSGSIHSIKT--NIIICLDILKIKNYYYQELPNIRIRTSPVLNVIQQRIKNIIDRDLLSELSEQDIDYLRTNLENCLWIPESLPRLAKSIRWNNAREVNTFYSLLSLWPKVSLESSLQLLGGNFFDEILRRFAVNNLRSILTNADVNLYLLQLIQALKYESYYFNDLAIYLIQSALRSKQLGQKFFWFLKSEMHNDTIKVYFAIINEAFCRGYWNFINIIRPQCIEIEKLIEISMILKNQRVELQLSTLKDYLRNDNFNEICKNVNSLLCLSEKQGNIIVDTCDVKKSKKRPIYLEWKNADIFSDLVNPTLKFIFKCGDDLRQDMLTLQILSIFDWIWKRQFQDMKLLPYGCLASGKDSGIIEAVKDAKTVMSIQRSHLSSAMQMDSFSLYRWIRSNNTTCEQFQKALETFTRSCAGYSVATFILGIRDRHPDNIMVNSKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIITIAEGCDKPSSSDKFNDFTVLCGKAYLKLREHSSLILTLYSLMIDSGLPELTKVQDLEYLRKTLSVDSTEEQALTYFNRQFYNAYTGNWTTKIDWLSHW 1021
BLAST of pi3k-like protein vs. TrEMBL
Match: A0A2R5LMV6 (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit OS=Ornithodoros turicata OX=34597 PE=3 SV=1) HSP 1 Score: 647.892 bits (1670), Expect = 0.000e+0 Identity = 391/1046 (37.38%), Postives = 602/1046 (57.55%), Query Frame = 3
Query: 192 FSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIANPNDI---VIFQYGADYNEFTTSTARQILQS---MTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKIL-----LDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLEN-ISINRFIIPPYFYQNIPQTKRRTRQD--SVSKMFSLLLISAQLI-CKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISK----VNYYYQEQ------SPVRIMG----SPIS---TTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQ---LSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQR-SNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
N V V LLP + + +R A+L IKD L + + +Y L + SSYIF + RDAE EE+YDES+ LC+L+L +L +E KGN +E +L S I IG + ++ + E+++ R+ L V K+ ++ A ++ ++ + + S L M C+++ T + K + + E ++E I K L L K++ A E Y+LKV ++ YLL + Y Y+++C+ P L L +E + N I + + P Y +N+ T+ ++ V MF + +++A + K+ K+YVR +++G + + P +++ V+ +P W+E L FD+Y +IPR+A+LC S+ ++R E + W NI++F+Y L+ G ++L+LWP K D NP GS S NR + L I I + V + EQ S +R+ +P + + ++I +I RD L E+SEQ+ L C V +SLP+L +++WN+ V Y LL++WP+++ E++L+LL + D +R+ AV+ L L++ ++ YLLQLVQ LKYE Y NDL FL++ +L N +G FFW LKSEMH+ ++ + F L+LE FCRG + + Q +EKL +++ LK +++D Q L L E DF + + S LN S G ++V C + S K+P++L W+N D E + + IFK GDDLRQD+LTLQ++ I D IW+ + D++++PY CL+TGK G+IE V++A+TVM+IQ+ +AA Q++S+ L++WI+ N+ +++ +A+ETFT SCAGY VATFILGI DR+PDNIMVN +GQ+FHIDFGH L + KKKFG+NRERVPFVLTEDF+ IA G++ P S +F F LCGKAYL L H++L++TL+++M+ +G+PEL + D+ YLRKTL VE E+ AL YF QF +AY G WTTK+DW H
Sbjct: 14 MPNTVMVDCLLPTGVIIQLNCARDATLESIKDDLWDKAQRYPLYRRL--GDPSSYIFVSITRDAEREEFYDESRRLCDLHLFQPILKIVEPKGNTEEKKLNSEIRLAIGGSAHEF----DDMKEHEVVDFRRGILAVCKEAVDTRDAGSDECRACYVYPPEIESSSRLPSNLENKLDKGVVMVCVWVLTDTNGKQTHTLEVHKDTHPENVIREAILKKLQKCSKLSKEEQLAR---------AEECQKHYLLKVCGVNQYLLKSY-PLSQYKYIRNCIAKGNMPQLMLMHKEAVYNAIPRSHYNTPSYMRRNVSTTQPQSTISLYRVDAMFGVKILNASYVNVKDVDKIYVRTGIYHGTES-LCPYRETQHVAHTNPKWDELLEFDLYIPDIPRSARLCVSICAVSQRKKREERCAIAWGNISLFDYKSVLLSGKVNLHLWPVPKGMDE-LLNPIGSIGSNPNREAPCLVIEIERFSGQVVFPTMEQIEEYVNSIIRLQSQTEKNPETWNESEKEQIHDVIKRDPLSEISEQEKMLLWKMRYYCFSVSDSLPKLLDALKWNSRDHVAQLYILLNQWPQVSPETALELLDCKYADLFVRKHAVRWLDQSLSDELLSRYLLQLVQVLKYEPYLENDLGKFLIKRSLLNYNIGHFFFWHLKSEMHDPAVALRFGLLLEGFCRGIGTHLKSVVKQVGALEKLTQLTDSLKERKDDTQKERLRFLMEQFSKPDFLDALQEFPSPLNNSCILGKLVVTECKILDSAKKPLWLLWKNPDYSVEHILEHHEIIFKNGDDLRQDMLTLQVIRIMDSIWQNEGLDLRMMPYACLSTGKHVGMIEVVRNARTVMNIQKKGGRMAAFQVDSTQLHKWIREKNKG-KRYKQAIETFTLSCAGYCVATFILGIGDRNPDNIMVNEEGQIFHIDFGHFLGHFKKKFGINRERVPFVLTEDFLYVIAKGAENPRKSKEFQSFQELCGKAYLLLHRHANLLITLFTMMLSTGIPELQSIDDISYLRKTLQVEKTEEQALEYFQNQFFEAYGGAWTTKVDWFFH 1040
BLAST of pi3k-like protein vs. TrEMBL
Match: A0A131YXN4 (Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit OS=Rhipicephalus appendiculatus OX=34631 PE=3 SV=1) HSP 1 Score: 647.121 bits (1668), Expect = 0.000e+0 Identity = 395/1043 (37.87%), Postives = 591/1043 (56.66%), Query Frame = 3
Query: 192 FSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG---FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN---PNDIVIFQYGADYNEFTTSTARQILQS--MTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQN--IPQTKRRTRQDSVSKMFSLLLISAQLI-CKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISK----VNYYYQEQ--------SPVRIMG--SPISTT---IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLK---EYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQR-SNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
N + V LLP + SR A+L IK+ L + + +Y L SSYIF + R+ + EE+YDE + LC+L+L +L +E KGN +E +L S I +G DN+ + +L+ K ++ E A+ P +I E + R++ + M C++ + K + + E ++E I K L + S E +M A E+ Y+LKV ++ YLL + Y Y+++C+ E P L L ++ + + I + +I P Y +N + T+ V + F + ++ A + K+ K+YVRV +++G + P + + VS +P W+E L F +Y +IPR+A+LC S+ ++R E + W N+++F+Y L+ G ++L+LWP K D NP GST S NR + L I + + V + EQ SP+ MG SP + T +I II RD L E+ EQ+ L C VP SLP+L + +WN V Y LL KW R++ E++L+LL + D +R++AV+ L L++ ++ YLLQLVQ LKYE Y NDL FL++ +L N +G FFW LKSEMH+ S+ + F L+LE FCRG + + Q +EKL +++ LK +++D LK E DF E ++ S LN S G++IV C + S K+P++L W+N D +E + + IFK GDDLRQD+LTLQ++ I D IW+++ D++++PY CL+TGK G+IE V++AKTVM+IQ+ +AA Q++S+ L++WI+ N+ +++ +A+ETFT SCAGY VATFILGI DR+PDNIMVN +GQ+FHIDFGH L + KKKFG+NRERVPFVLTEDF+ IA G + P S +F F LCGKAYL L H++L++TL+++M+ +G+PEL + D+ YLRKTL VE E+ AL YF QF +AY G WTTK+DW H
Sbjct: 14 MPNTIVVDCLLPTGIIIPLTCSRDATLESIKEDLWENAQKYPLYRHL--GEPSSYIFVSITREGDKEEFYDEYRRLCDLHLFQPILKVVEPKGNTEEKKLNSEIRLAVGGCAHEFDNMKDSEVIDFRRNILSVCKDAVDTRNTGSEECRASYVYPPEI------ESSEELPANLERKLDKGLVMVCVWGLSETGEKQKHTLEVHKDTVPEAVIREAILKKLKCSRHSREEQVAM-----AQEHQHNYLLKVCGVNQYLLKSY-PLCRYKYIRTCIAKGEIPQLMLMLKDAVYKAIPPSNYITPSYVRRNPSLSATQPTVSLYKVDESFRVKILGASYVNVKDVDKIYVRVGIYHGTEA-LCPFRDTEHVSHSNPKWDELLEFQMYIPDIPRSARLCVSICAVSQRKKREERCAIAWGNVSLFDYKSVLLSGRVNLHLWPVPKGMDE-LLNPLGSTGSNPNREAPCLVIELDRFSGQVVFPTMEQIEEYASFVSPLESMGEESPENWTENDKDQIHEIIKRDPLSEILEQEKMLLWRMRYYCYTVPNSLPKLLDASKWNCRDHVAQLYRLLKKWKRVSPETALELLDCKYADMFVRKYAVEWLDG-LSDELLSQYLLQLVQVLKYEPYLENDLGKFLIRRSLLNYNIGHFFFWHLKSEMHDPSVAVRFGLLLEGFCRGIGTHLKSVVRQVGALEKLTQLTDSLKERKDDTPKERLKFLIEQFSKPDFLEALQHFPSPLNNSCILGDLIVNECRILDSAKKPLWLLWKNPDHLAEQILDHHEIIFKNGDDLRQDMLTLQVIRIMDSIWQKEGLDLRMMPYACLSTGKHVGMIEVVRNAKTVMNIQKKGGRMAAFQVDSTQLHKWIRDKNKG-DRYKQAIETFTLSCAGYCVATFILGIGDRNPDNIMVNEEGQIFHIDFGHFLGHFKKKFGINRERVPFVLTEDFLHVIARGQENPRKSKEFQSFQELCGKAYLLLHRHANLLITLFTMMLSTGIPELQSIDDIGYLRKTLQVEKPEEQALEYFQNQFFEAYGGAWTTKVDWFFH 1038
BLAST of pi3k-like protein vs. TrEMBL
Match: A0A1E1XFL8 (Putative phosphatidylinositol 3-kinase vps34 involved in signal transduction (Fragment) OS=Amblyomma aureolatum OX=187763 PE=2 SV=1) HSP 1 Score: 645.966 bits (1665), Expect = 0.000e+0 Identity = 390/1043 (37.39%), Postives = 593/1043 (56.86%), Query Frame = 3
Query: 192 FSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG---FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN---PNDIVIFQYGADYNEFTTSTARQILQS--MTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQN--IPQTKRRTRQDSVSKMFSLLLISAQLI-CKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISK----VNYYYQEQ--------SPVRIMGSPISTTI-----QRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDL---QLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQR-SNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
N + V LLP + SR A+L IK+ L + + +Y L SSYIF + RD + EE+YDE + LC+L+L +L +E KGN +E +L S I +G DN+ + +L+ K ++ E A+ P +I E + R++ + M C++ + K + + E ++E I K L + + E ++ A E+ Y+LKV ++ YLL + Y Y+++C+ + P L L ++ + + I + +I P Y +N + T+ V + F + ++ A + K+ K+YVRV +++G + + P + + V +P W+E L F +Y +IPR+A+LC S+ ++R E + W N+++F+Y L+ ++L+LWP K D NP GST S NR + L I + + V + EQ SP++ +G T ++++ II RD L E+SEQD L C VP SLP+L + +WN+ V Y LL KW R++ E++L+LL + D +R++AV+ L L++ ++ YLLQLVQ LKYE Y NDL FL++ +L N +G FFW LKSEMH+ S+ + F L+LE FCRG + + Q +EKL +++ LK +++D +L L E DF E ++ S LN S G++IV C + S K+P++L W+N D +E + + IFK GDDLRQD+LTLQ++ I D IW+++ D++++PY CL+TGK G+IE V++AKTVM+IQ+ +AA Q++S+ L++WI+ NR +++ +A+ETFT SCAGY VATFILGI DR+PDNIMVN +GQ+FHIDFGH L + KKKFG+NRERVPFVLTEDF+ IA G + P S +F F LCGKAYL L H++L++TL+++M+ +G+PEL + D+ YLRKTL VE E+ AL YF QF +AY G WTTK+DW H
Sbjct: 15 MPNTIMVDCLLPTGIIIPLSCSRDATLESIKEELWENAQKYPLYRHL--GEPSSYIFVSITRDGDKEEFYDEYRRLCDLHLFQPILKVVEPKGNTEEKKLNSEIRLAVGGCAHEFDNMKDSEVIDFRRNILSVCKDAVDTRNTGSEECRASYVYPPEI------ESSEELPANLERKLDKGLVMVCVWGLSDSGEKQKHTLEVHKDTVPEAVIREAILKKLKCSRLAREEQVAL-----AQEHQHHYLLKVCGVNQYLLKTY-PLCRYKYIRTCIAKGDIPQLMLMLKDAVYKAIPPSNYITPSYVRRNPSLSATQPTVSLYKVDESFRVKILGASYVNVKDVDKIYVRVGIYHGTES-LCPFRDTEHVVHSNPKWDETLEFQMYIPDIPRSARLCVSICAVSQRKKREERCAIAWGNVSLFDYKSVLLSSRVNLHLWPVPKGMDE-LLNPLGSTGSNPNREAPCLVIELDRFSGQVVFPSMEQIEEYASFVSPLQSLGEENPETWTEVEKEQVQEIIKRDPLSEISEQDKMLLWKMRYYCYTVPNSLPKLLDASKWNSRDHVAQLYRLLRKWKRVSPETALELLDCKYADMFVRKYAVEWLDG-LSDELLSQYLLQLVQVLKYEPYLENDLGKFLIRRSLLNYNIGHFFFWHLKSEMHDPSVAVRFGLLLEGFCRGIGTHLKSVVRQVGALEKLTQLTDSLKERKDDTPKERLKYLTEQFSKPDFLEALQHFPSPLNNSCILGDLIVNECRILDSAKKPLWLLWKNPDHLAEQILDHHEIIFKNGDDLRQDMLTLQVIRIMDSIWQKEGLDLRMMPYACLSTGKHVGMIEVVRNAKTVMNIQKKGGRMAAFQVDSTQLHKWIKEKNRG-DRYKQAIETFTLSCAGYCVATFILGIGDRNPDNIMVNEEGQIFHIDFGHFLGHFKKKFGINRERVPFVLTEDFLHVIAKGQENPRKSKEFQSFQELCGKAYLLLHRHANLLITLFTMMLSTGIPELQSIDDIGYLRKTLQVEKSEEQALEYFQNQFFEAYGGAWTTKVDWFFH 1039
BLAST of pi3k-like protein vs. Ensembl Cavefish
Match: zgc:158659 (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [Source:NCBI gene;Acc:103032909]) HSP 1 Score: 624.394 bits (1609), Expect = 0.000e+0 Identity = 386/1061 (36.38%), Postives = 588/1061 (55.42%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKK---EHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTC------LYITTLISYKSVNPF-KCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL----LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVN---YYYQEQS--------PVRIMG--------------SPISTT-IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LPN + R+A L +K L E + +Y LL S YIF GV ++AE EE+YDE++ LC+L L +L +E GN +E ++N IGF + E+ + D E+ + R+S L V ++ E E A+ + ++ + ++ Q+ Q + C L +T + N K + I+ + ++ I + + K S + + E +Y+LKV D YLL + Y Y++SC+ + P L L ++ L + + F+ P Y + PQ S SL L+ +L+C ++ K+YVR +++G + + V +P WNE L +DIY +++PR+A+LC S+ K +G E L W N+N+F+Y L+ G + L LWP ++ NP G S N+ + + + S N + EQ R +G S IS +++++++ RD LYELSEQ+ D+L + C+ +PESLP+L +++WN+ EV+ Y LL WP + ES+L+LL NF D ++R+FA++ L LT+ I+ YLLQLVQ LKYE Y N L+ FL++ AL N+++G FFW LKSEMHN+++ F L+LEAFCR ++ + Q ++KLV ++ LK +++D Q+ L E++ D+ E + S LN + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE VK++ T+M IQ + + A+Q NS++L+ WI+ N+ E + KA++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + +F F +C KAYL +R+H+SL + L+S+++ G+PEL D+ YLRKTL++E ++ AL YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCCLPNGMLVSLECLREAPLISVKQQLFAEARKYPLYH--LLQEESCYIFVGVTQEAEREEFYDETRRLCDLRLFHPILKVIEPLGNREEK----ILNREIGFAIGMPICEFELVKDPEVQDFRRSILSVCREAMEEREGGGAHTQALYVYPP-------SVESSPQLPQHIYCKLDKGRLIVTIWVVVSPSNAKQKYTLKIAHDCLPEQLIAEAIRKKTRSMHLS-AQQLRLCVQEYQGQYILKVCGCDEYLLEKY-PLSQYKYIRSCITVGKLPHLMLVSKDSLYSQLPASGFVAPSY-SRRTPQPSPCPGGSDPSPPRSLWAFNTLLRVRLLCATYVNVNIRDIDKIYVRTGIYHG-GEPLCDNVNTQRVPCSNPRWNEWLTYDIYLTDLPRSARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYKDTLVSGKVALGLWPVPHGLED-LLNPIGVAGSNPNKETPCVELEFSSFNQMVVFPDEQQIEEHANWIVSRELGYNYSLSLSNRLACDSTISQAELEQLRSLCSRDPLYELSEQEKDFLWRHRHYCVNIPESLPKLLLAVKWNSRDEVSQMYCLLRDWPLMQPESALELLDCNFPDPMVREFALRCLIQGLTDDKISQYLLQLVQVLKYEMYLDNPLARFLIKKALTNQRIGHFFFWHLKSEMHNKTVSRRFGLLLEAFCRACGMYLKHLNRQVEAMDKLVNLTDTLKHEKKDETQKTQMKFLVEHMSRPDYMEALQGFVSPLNPVHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFTNNEVIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVKNSYTIMQIQCKGGLKGALQFNSNTLHHWIKEKNKG-EGYDKAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKENGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGMQECTKTKEFERFQEMCYKAYLAIRQHASLFINLFSLLLGCGMPELQSFDDIAYLRKTLALEKSQQEALEYFTKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Cavefish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:103041606]) HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0 Identity = 377/1058 (35.63%), Postives = 579/1058 (54.73%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E N P+ ++ Y + E + + I + I + S N K T+ V E + + KK + + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ I T I +++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + ++ +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NSS+L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDVNGPHSRALYVYPPNV-ESSPELPKHIFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEVSSKALWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKG-ETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Cavefish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:103041606]) HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0 Identity = 377/1058 (35.63%), Postives = 579/1058 (54.73%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E N P+ ++ Y + E + + I + I + S N K T+ V E + + KK + + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ I T I +++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + ++ +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NSS+L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDVNGPHSRALYVYPPNV-ESSPELPKHIFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEVSSKALWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKG-ETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Cavefish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:103041606]) HSP 1 Score: 606.675 bits (1563), Expect = 0.000e+0 Identity = 377/1058 (35.63%), Postives = 579/1058 (54.73%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG F+L P+ + R++ L V K E N P+ ++ Y + E + + I + I + S N K T+ V E + + KK + + E KY+LKV D YLL I Y YV+SC+ P L L ++ L + ++ F +P Y + T + S ++++ + +++C ++ K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ I T I +++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + ++ +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NSS+L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQ---------DFRRNILNVCKDSVELRDVNGPHSRALYVYPPNV-ESSPELPKHIFGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKY-PISQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEVSSKALWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKG-ETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1061
BLAST of pi3k-like protein vs. Ensembl Cavefish
Match: pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:103041606]) HSP 1 Score: 558.14 bits (1437), Expect = 0.000e+0 Identity = 289/712 (40.59%), Postives = 436/712 (61.24%), Query Frame = 3
Query: 1188 KLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY---------------------YYQEQSPVRIMGSPISTT--IQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVK-FNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
K+YVR +++G ++ + V +P WNE L +D+Y +IPR A+LC S+ K +G E L W N+N+F+Y L+ G + LNLWP ++ NP G T S N+ + L + S V + Y Q R+ I T I +++ + +RD L E++EQ+ D+L + + C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL N+ D ++R FAV+ L LT+ ++ YL+QLVQ LKYE Y N L FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E ++ D+ + ++ +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NSS+L++W++ N+ E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G + + F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 271 KIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVAGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRLARDHIITEADIDQLRQLANRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKRALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSSTLHQWLKDKNKG-ETYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH 979 HSP 2 Score: 65.0846 bits (157), Expect = 4.244e-10 Identity = 40/106 (37.74%), Postives = 56/106 (52.83%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGF 521
+ V LLPN + R+A+L IK L KE + ++ LL +SYIF V ++AE EE+YDE++ LC+L L L +E GN +E L I IG
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGM 123
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Match: pik3cd (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta [Source:ZFIN;Acc:ZDB-GENE-040426-1128]) HSP 1 Score: 358.992 bits (920), Expect = 7.940e-114 Identity = 186/440 (42.27%), Postives = 276/440 (62.73%), Query Frame = 3
Query: 1917 TNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEI-----SRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
++ +++ YLLQLVQ LKYE Y +DL+ FLL+ AL N+ +G FW L+SEMH ++ + F LMLEA+CRG + + + Q + K+ I S +K+ + + + L+ + E + S L + VE C SK +P+++ + + E + IFK GDDLRQD+LTLQ+L + D +WK+Q D++++PYGCL+TG +G+IE V+ A+T+ +IQ +SNI A N +L W++A N + +A+E FT SCAGY VAT++LGI DRH DNIM+ GQLFHIDFGH L N K KFG+ RERVPF+LT DF+ I +G + +S KF+ F C +AYL LR++ L L L+S M+ +GLPELT +D++YL++TL++E E AL +F ++F +A R +W TK+ W++H
Sbjct: 1 SDDELSQYLLQLVQVLKYEPYLDSDLAKFLLERALANRCIGHFLFWHLRSEMHVPAVSLQFGLMLEAYCRGSIAHVRSLMKQCEALTKMRAINDLVKSSSMKSNNKAKVIDAMHASLRQTSYTEALTGLQSPLKPCVILSQLNVEKCKFMNSKMKPLWMVYSD-----EEGLEPTGAIFKNGDDLRQDMLTLQMLKLMDNMWKQQGLDLRIVPYGCLSTGDKTGLIEMVRRAETIANIQLDKSNIAATAAFNKDALLNWLKAKNHR-DALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRETGQLFHIDFGHFLGNFKSKFGIKRERVPFILTYDFVHVIQEG--KTTNSEKFDRFRRYCERAYLILRKNGHLFLNLFS-MLAAGLPELTSPKDIQYLKETLALEKREDDALKHFCQKFNEALRESWKTKVMWMAH 431
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002453.1 (pep scaffold:Pmarinus_7.0:GL482029:21191:33947:1 gene:ENSPMAG00000002221.1 transcript:ENSPMAT00000002453.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 357.066 bits (915), Expect = 2.678e-106 Identity = 234/726 (32.23%), Postives = 376/726 (51.79%), Query Frame = 3
Query: 1182 NSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL----------------IEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQ---DNGYFNPGGSTDSYKNRNSVI----------LSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESS--LQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMH-NESIKIYFALMLEAFCRG-----YLNFMTVIRP----QSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSE-KQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQ-----ANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 3218
++++YV+ +++G R+A S + W + L F I ++P A L SL + R LL + N+ + ++ L +G L +WP ++ Q D G + + + R +V+ +++ S+ ++ + R S + +K +++ D L + ++ L ++ +SLPRL +++ W ++ V + L W + + S ++LL GNF D +R+ AV+ L A N +I L+LLQLVQALK+E Y+ + L+ FL+Q ALR+K+LG FFWFL+SE+ + FA++LEA+ RG NF+ ++ + +G + +++ + ++ L+ C V L + +E C V SKK+P++LE+ AD S +K IFK GDDLRQD+L LQ L+I D IW + D+ LLPYGC+ATG ++G+IE V +A TV SIQ + N L W+ A R EQ +A+E F SCAGY +AT++LGI DRH +NIM+ G LFHIDFGHIL N KK +GV+RERVPFVLT DF+ + ++ ++ F F+ C +AYL LR H +L++TL+++M +G+PE+T +D+E++R+ L V + E A + + WT +++W H
Sbjct: 357 DAEVYVQAGVYHG-KVRLASVMTSKRPLQEEIVWGDWLEFGIRMKDLPLGACLNLSLYSVRSQSCCDRRWSGLLPSGSRSLEARLLHYVNMTLIDHRSLLRQGEFVLYMWPLQQGQRAPDPSALPSGANPE--QERAAVVSVLLDTYDCPVALPRSQAGVFHMPERAKRFFAEG-SVQDEFLKHLVNVDPLSPVEAPELALLWQMRDSLSRTAQSLPRLLRAVDWGSLECVRETHGFLQHWSMTDFDLSIAMELLDGNFVDGFVRRMAVERL-AASGNDEILLFLLQLVQALKFEPYHDSPLARFLIQRALRSKRLGHFFFWFLRSEIAVCAQSRARFAVLLEAYLRGCGRATLHNFVQQVKLIDSLRIVGDKMQLQLGNLYNVPPNGAPIAPCPPLLRTRVHLHICACVCVPLYVHTCAYTCACIEKCKVLASKKKPLWLEFHRADSTS-LDDSNVKLIFKNGDDLRQDMLILQTLNIMDSIWDSEGLDLCLLPYGCIATGYNTGVIEVVPNAHTVASIQVEK--GGIPRNEGYLKTWLDEQMPLAGQR--EQNLQAVEKFMHSCAGYCMATYVLGIGDRHNENIMITKNGNLFHIDFGHILGNIKKFWGVSRERVPFVLTPDFLCILGAHKNK---NLYFQRFVDTCCRAYLALRRHKNLLITLFNMMATTGMPEVTP-RDIEHMREALVVRATEADAEAHIRSEIEHCIDKGWTVQVNWWMHL 1068
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Match: pik3c2a (phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha [Source:ZFIN;Acc:ZDB-GENE-030328-39]) HSP 1 Score: 269.626 bits (688), Expect = 4.442e-76 Identity = 198/675 (29.33%), Postives = 332/675 (49.19%), Query Frame = 3
Query: 1293 LNFDIYYSNIPRNAKLCFSL---IEKTERGGNE---------VLLGWANINIFNYFGKLIEGSIDLNLWP------FEKIQDNGYFNPGG---STDSYKNRNSVILSINISK---VNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN-----ESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETC-KNV-SSLLNLSEKQG--NIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNR-ERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+N + S +PR L SL + + GG+ LGWA + +FN+ L G+ L L P P D + +I +++ + Y +++ P T + + I+ +D + L E D L + +LP L S + + Y+LL WP ++ +L LL NF D+ +R+ AV+ + A +++ ++ YL QL+QALK+E Y N L FLL ++ N ++ +W LK + + S ++ AL+ C G + Q+ + L ++ ++ + + L+E + + +TC +N SS L + + + C S P+ + + NAD E ++ +FK GDDLRQD+LTLQ++ I D IW ++ DM+++ + C++TGK+ G++E V + T+ IQ + + L W+Q +N T +++ KA+E F SCAG VAT++LGI DRH DNIM+ T G +FHIDFG L + + + R +R PFVLT D I +G +RP + +F F+ LC +AY +R+H++L L L +M+ SG+PEL VQDL+Y+ + L ++ + A F R ++ G+ TK+++ H
Sbjct: 1 VNLPVQVSQLPRETVLRVSLQGVPQPSASGGSPDSSKQRRSPEQLGWATMPLFNFRQVLTSGTQLLCLGPPSQASYAASCSAAHLLQPDSVILQLDFPPTKLDIIFPTPMARGLWLQYNFEDMDP---------DTRKSLHTIMSKDSVLGLGEDDKVLLWEKRHHLHAQANALPWLLASAPSWQCSALPDVYALLGHWPALSPVHALMLLHSNFADQEVRRTAVEWI-ACVSDDELADYLPQLLQALKHECYLDNALMRFLLGRSMSNIRIAHYLYWLLKDTLEDGHFGGRSHRVLGALLC---CCGR-TLRHDLESQTRLVHTLATVAEKVRQATGSTRQAMLQEGM--EKVQQTCFRNAGSSRLPICPSLAIRGVNQKACSFFNSNAVPLKVSFLNADPSGE----DIQVMFKVGDDLRQDMLTLQMIKIMDKIWLQEGLDMRMVLFKCISTGKERGMVELVLASDTLRKIQVEHGVTG-SFKDKPLAEWLQKHNPTEQEYEKAVENFIYSCAGCCVATYVLGICDRHNDNIMLRTTGHMFHIDFGKFLGHAQMFGNIKRCDRAPFVLTSDMAYVI-NGGERP--TSRFQHFVDLCCQAYNLIRKHTNLFLNLLGLMMSSGIPELADVQDLKYVYEALMPQATDTEATAQFTR-LIESSLGSMATKVNFFIH 650
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010071.1 (pep scaffold:Pmarinus_7.0:GL484237:218:13057:-1 gene:ENSPMAG00000009114.1 transcript:ENSPMAT00000010071.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 188.734 bits (478), Expect = 6.709e-52 Identity = 91/239 (38.08%), Postives = 146/239 (61.09%), Query Frame = 3
Query: 2439 KCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFN 3155
+ GDDLRQD+LTLQ++ + + +W ++ DM+++ + CL+TGK G++E V A+T+ IQ + + + L W++ +N + +Q+ +A+E F SCAG VAT++LGI DRH DNIM+ T G +FH+DFG L + + + R+R PFVLT D + + +G DRP S F +F+ LC +AY +R+H+ L+ L ++ D G P ++ L Y+R L ++ E A F
Sbjct: 4 QTGDDLRQDMLTLQVMRVMESVWLQEGLDMRMVRFRCLSTGKQRGMVELVPGAETLRRIQGEHGVTG-SFKDTPLALWLRKHNPSEQQYQQAVENFIYSCAGCCVATYVLGICDRHNDNIMLRTTGHMFHVDFGKFLGHAQMFGNIKRDRTPFVLTAD-MAYVMNGGDRPTSS--FQQFVELCCQAYNAIRKHAGLLFNLLGLVSDGGEPGAVHMEGLVYVRDALRPQATEAEAAELFT 238
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008978.1 (pep scaffold:Pmarinus_7.0:GL477391:15964:91650:-1 gene:ENSPMAG00000008040.1 transcript:ENSPMAT00000008978.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 126.331 bits (316), Expect = 1.890e-29 Identity = 81/266 (30.45%), Postives = 136/266 (51.13%), Query Frame = 3
Query: 2433 IFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHI--DFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKL--REHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 3218
IFK GDD RQD+L LQ++ +F I++ D+ + PY +AT G+IE + D K+ + R I + Y Q + + E F KA F RS A YS+ F+L I+DRH NIM++++G L HI DFG + + G N P + D + I G +++ F FM +C + YL + R + +++L ++M+D+GLP + Q ++ L++ + E+ A NY + + + N + D + ++
Sbjct: 1852 IFKVGDDCRQDMLALQIIGLFKNIFQLVGMDLFVFPYRVVATSPGCGVIECIPDCKSRDQLGRQTDIGMYE------YFRNQYGDESTEAFQKARYNFIRSMAAYSLLLFLLQIKDRHNGNIMLDSQGHLIHIVLDFGFMFESSP---GGNLGWEPDIKLTDEMVMIMGGK---MEATPFKWFMEMCVRGYLAVSNRPYMDAVISLVALMLDTGLPCF-RGQTIKLLKQRFAPNQSERDAANYMIKIIQNCFLSNRSKTYDMIQYY 2104
BLAST of pi3k-like protein vs. Ensembl Yeast
Match: VPS34 (Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p; a fraction is localized, with Vps15p, to nuclear pores at nucleus-vacuole junctions and may facilitate transcription elongation for genes positioned at the nuclear periphery [Source:SGD;Acc:S000004230]) HSP 1 Score: 142.895 bits (359), Expect = 3.641e-35 Identity = 157/620 (25.32%), Postives = 276/620 (44.52%), Query Frame = 3
Query: 1497 NPGGSTD-SYKNRNSVILSINIS-KVNYYYQEQSPVRIMGSPISTTIQRIK-----AIIDRDWLYELSEQD-----IDY-----LRSNLENCLWV--------PESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLL-----------------------------------------------QLVQALKYES---------YYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAF-------CRGYLN----FMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSI--QRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPEL 3074
NPG STD NRN + I++ K + + P + PI +R++ A +D+ ++ ++D I+Y L ++ + +W ++L +L +S +E L+ W I+++ +L+LL F + +R +AV L+ ++ ++ LYLL +L++++ ES + L+ FL++ AL N +LG F+W+LKSE + K Y +L +F R LN + V+R I++L + + A++ +L + L+ ++ + ++ L+ ++ ET V KS P+ + ++ + + P +FK GDDLRQD L +Q++S+ + + K + D+KL PY LATG G IE + + T+ SI + I+ ++++ N T L+ F +SCAGY V T+ILG+ DRH DN++V G FH DFG+IL K F ++P + E F G+ +S +++F C AY LR ++ LIL L+ +M S +P++
Sbjct: 235 NPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKA-SDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESED---KPYLDQILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTT----AKKMELLVHLLETKVRP---LVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFK-----TTLNQP-YHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPN-DTLASILSKYHGILGYLKLHYPD-------ENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPP-LMKLPPQIIEAF-----GGA----ESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDI 819
BLAST of pi3k-like protein vs. Ensembl Yeast
Match: STT4 (Phosphatidylinositol-4-kinase; functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization [Source:SGD;Acc:S000004296]) HSP 1 Score: 134.806 bits (338), Expect = 2.862e-32 Identity = 81/240 (33.75%), Postives = 122/240 (50.83%), Query Frame = 3
Query: 2433 IFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQA--NNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVE-SDEKAAL 3143
IFK GDD RQD+L LQL+S+F IW D+ + PY AT G+I+ + ++ + + R + + LY + + N + +F A F +S AGYSV +++L +DRH NIM + +G HIDFG I + G+ E VPF LT++ +K + P + +F LC KAYL R H I+ + M+ SGLP + + LR + +D +AAL
Sbjct: 1645 IFKVGDDCRQDVLALQLISLFRTIWSSIGLDVYVFPYRVTATAPGCGVIDVLPNSVSRDMLGREAV--------NGLYEYFTSKFGNESTIEFQNARNNFVKSLAGYSVISYLLQFKDRHNGNIMYDDQGHCLHIDFGFIFDIVPG--GIKFEAVPFKLTKEMVKVMGGSPQTP----AYLDFEELCIKAYLAARPHVEAIIECVNPMLGSGLPCFKGHKTIRNLRARFQPQKTDHEAAL 1870
BLAST of pi3k-like protein vs. Ensembl Yeast
Match: PIK1 (Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokinesis through the actin cytoskeleton; may control nonselective autophagy and mitophagy through trafficking of Atg9p [Source:SGD;Acc:S000005211]) HSP 1 Score: 98.9821 bits (245), Expect = 2.266e-21 Identity = 81/298 (27.18%), Postives = 147/298 (49.33%), Query Frame = 3
Query: 2358 KKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRS---NIIAAMQMNS----SSLY-RWIQA-NNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIM--------IDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKI 3200
+K Y +EN D+ S I K GDDLRQ+ Q++ IW ++ D+ + L T ++G++E + +A +V SI+++ +I +++ +SL +++A N ++ +A + F S A YSV ++L ++DRH NIM++ +G + HIDFG +L+N G E PF LT ++I+ + ++ F +F+ L ++ LR+++ I+++ IM D+G E T VQ LR+ ++ EK ++ G+ T+I
Sbjct: 777 RKTSEYGHFENWDLCS--------VIAKTGDDLRQEAFAYQMIQAMANIWVKEKVDVWVKRMKILITSANTGLVETITNAMSVHSIKKALTKKMIEDAELDDKGGIASLNDHFLRAFGNPNGFKYRRAQDNFASSLAAYSVICYLLQVKDRHNGNIMIDNEGHVSHIDFGFMLSNSPGSVGF--EAAPFKLTYEYIELLGG-----VEGEAFKKFVELTKSSFKALRKYADQIVSMCEIMQKDNMQPCFDAG--EQTSVQ----LRQRFQLDLSEKEVDDFVENFLIGKSLGSIYTRI 1053
BLAST of pi3k-like protein vs. Ensembl Yeast
Match: TOR1 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827]) HSP 1 Score: 63.5438 bits (153), Expect = 1.638e-10 Identity = 55/201 (27.36%), Postives = 91/201 (45.27%), Query Frame = 3
Query: 2427 KFIFKCGDDLRQDILTLQLLSIFDWIWK------------RQFQDMKLLP-YGCLATGKDSG----IIEAVKDAKTV-----------MSIQRSNII----------AAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVN-TKGQLFHIDFGHILNNR--KKKFGVNRERVPFVLT 2906
K++ K +D+RQD L +QL + + + K +Q+ + L P G L +S +I +DAK + M+ N+ A LY+ + +R+ E + + T+TRS A S+ +ILG+ DRHP N+M++ G++ HIDFG ++K+ E+VPF LT
Sbjct: 2120 KYVLKGHEDIRQDSLVMQLFGLVNTLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAKKIPLNIEHWVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYP---EKVPFRLT 2317
BLAST of pi3k-like protein vs. Ensembl Yeast
Match: TOR2 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686]) HSP 1 Score: 63.5438 bits (153), Expect = 1.797e-10 Identity = 51/201 (25.37%), Postives = 89/201 (44.28%), Query Frame = 3
Query: 2427 KFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQ----DMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAA-----------MQM-----------------------NSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVN-TKGQLFHIDFGHILNNR--KKKFGVNRERVPFVLT 2906
K++ K +D+RQD L +QL + + + + + + + Y + SG++ V ++ T + R + A +QM LY+ + +R+ E + + T+TRS A S+ +ILG+ DRHP N+M++ G++ HIDFG ++KF E+VPF LT
Sbjct: 2124 KYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAKKIPLNIEHWVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFP---EKVPFRLT 2321
BLAST of pi3k-like protein vs. Ensembl Nematostella
Match: EDO42011 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2J3]) HSP 1 Score: 505.368 bits (1300), Expect = 1.189e-161 Identity = 348/1059 (32.86%), Postives = 548/1059 (51.75%), Query Frame = 3
Query: 177 YYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLI-----SYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSF----EFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSV-SKMFSLLLISAQLICKENSK----------LYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLI--------EKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNS---VILSINISKVNYYY----------QEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYL-RSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQ---LSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIA-AMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ + S V V LLP + V +A+L EIK+ L +E + ++ LL SSY+F VN + EE DE++ L ++ +L +E+KG+ +E L+S I+ IG NL + D Y+E + KE L + + + +E T + Q L I+ I S K ++ F +S + T E + ++L K+ + +FD D YVLK+ +SYLL ++ Y Y+ C+ + P LSL R L +N ++ I V S SL I QL K S + VR A+++G N ++ +++ S + P WNE +N +I +IPR A+LC L + ++ + + L W N+ +F++ G L +G + ++ WP + + NP G+ S N ++ +++ N Y E + I +++++ +IDR+ L + E D +++ R+ +E + P SL RL ++WN +V LL WP ++ E +L+LL N+ D+ +R+FAV+ + + ++D+ Y+LQLVQ LKYESY +L+ FLL+ L N+ LG + FW L++EMHN + + F LMLEA+CRG M ++ Q + K+ IS +L+ D + L T+KE L+ + + ++S LN S + + V+ C SK RP++L++EN F E P +K IFK GDDLRQD+LTLQL+ I D +WK+ D++++PYGCL+TG G+IE V +++T+ IQ + A N + + W+ N + E +A F SCAGY VAT++LG+ DRH DNIMV+ GQLFHIDFGH L N K KFG+ RERVPFVLT+ F+ I G+D ++ F EF +C +A+L LR SL++ L+ +M+ +G+PEL + D+ YLRKTL++ E+ AL YFNR+F +A +W T I+W H
Sbjct: 10 WASLSACTPVDVDCLLPTGVLIPIEVRIEATLGEIKNKLWREAASYPLFN--LLKEMSSYVFVCVNLQGKQEELVDENRQLIDVRPFRPMLKLIEKKGDREEKLLSSKISVLIGKNLHEFDQMKNPEVDEFRRRY-AEYVEGIAKERSKLDWEGRAMYAYPVEIEQSEETPAYVAQKLNENRRFLISVAIRNNRASMKDMHAF----NVSAD-TFPEELLVLVLKKRGAIMGVQDFDNPKD-----------YVLKIVGRESYLLGEY-SLLRYRYISECIAQGKRPQLSLVRRVSL---GVNE-LMDVSGKSGIQHRPPPPLPPKVESAELSLWSIETQLRVKILSADNINVGDVMMVGVRGAIYHG-NEVLSDIKQTKPQSGNKPLWNEFINLNILVCDIPRMARLCLVLFGVYVKAAARRKKKNLDYIPLAWVNVTLFDFRGNLRQGPLTIHAWPVPETMPD-LLNPIGTVVSNINTSTSPCLVIEFQRYANNVVYPAYDKILQLAAETTDQEIFKKTGDNELEQLRQVIDREPLAPIFELDKEFVWRARMECRDYYPHSLGRLLSCVKWNCKEDVAQMQVLLQIWPEMHPELALELLDCNYADQKVREFAVRCIEK-MGDSDLMHYMLQLVQVLKYESYLDCELARFLLKRTLNNQNLGHELFWLLRAEMHNPEVSVRFGLMLEAYCRGSPAHMKSLQKQLEALNKMKTISSLLQHVDRDKRAQGLQTMKECLQQKTYQDALSRLTSPLNPSYRLKQLKVDNCKYMDSKMRPLWLDFEN---FDELGEP-VKIIFKSGDDLRQDMLTLQLIRIMDRLWKKDGLDLEMIPYGCLSTGDHVGMIEVVTNSETIAKIQMKQMGAITGAFNKTCILDWLADRNGSKEALVEATHRFMLSCAGYCVATYVLGVGDRHSDNIMVHENGQLFHIDFGHFLGNFKNKFGIRRERVPFVLTDHFVHVITRGND---NTEGFQEFRRICEQAFLVLRRRGSLLINLFVMMLSAGIPELRSLDDIGYLRKTLNLNVSEEKALEYFNRKFNEAVDNSWKTSINWAIH 1034
BLAST of pi3k-like protein vs. Ensembl Nematostella
Match: EDO45977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRA6]) HSP 1 Score: 292.738 bits (748), Expect = 3.169e-82 Identity = 216/664 (32.53%), Postives = 337/664 (50.75%), Query Frame = 3
Query: 1281 WNEKLNFDIYYSNIPRNAKLCFSLI-EKTERGGN---EVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGS-TDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDI-DYLRSNLENCLW--------VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIG-----IEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
W + L FDI +PR ++LC +L K GN LGW + +FN+ G L+ G+ L LWP K NP GS T + + NSV+L + + Y E P + D E+ +D+ + L+ N + LW VP +LP + S + + Y LL W ++ +++LL NF D+ +R AV+ + A ++ ++ YL QLVQALKYE Y+ + L+ FL++ AL N +L FWFLK ++ F ++L G LN + + + +L++++R +K+ ++ + + L++ L C + E G + V +C S P+ L + N D F E + IFK GDD+RQD LT+QL+ I + IW ++ D+K++ Y C+ATG G+IE V D++T+ I + S+ RW+ N +++ +A+E FT SCAGY VAT++LGI DRH DNIM++ G LFHIDF IL + + R+R PFVLT D I +G RP S +F F+ LC +A+ +R HS+L L L S+M++SG+ L V DL Y+R +L + E A F R ++ +W T++++ H
Sbjct: 370 WGDWLKFDIPVKRLPRESRLCLTLYGTKPSSKGNPSARSALGWVALQLFNFNGVLLTGTQILGLWPDSKA------NPVGSCTSNLLHPNSVLLLVTFER---YLSEIVFPDCSDFPGFDDMDHCIPEADYGLFEEILMKDLFNELKPNERSILWEHRFYCRSVPRALPLVLSSAPSWEIQSLPEIYKLLHTWSPMSPVDAMELLKVNFPDRHVRSMAVRWM-ANFSDDELCDYLPQLVQALKYEIYHDSALTRFLVRRALGNVRLMHLLFWFLKDKISEPQFGQRFQVILG----GLLNICGEAQKEEFTFQDDLVTELIKVARKVKSAKDSARNNILQQELAALAGKLCCVFRLPITPSLEVVG-MDVRSCGYFTSNSAPLRLVFRNVDPFGE----NVNVIFKMGDDMRQDTLTMQLVGIMNKIWLQEGLDLKIITYQCMATGPGMGMIEIVSDSQTLREIHTEFGLTG-SFKDESINRWLLKFNPDEKEYRRAVENFTASCAGYCVATYVLGICDRHNDNIMIHRSGHLFHIDFSKILGHAQMFGNFKRDRAPFVLTPDMAYVI-NGGYRP--SPRFQHFIDLCSRAFNLIRRHSNLFLNLLSLMLNSGIGSLGNVSDLRYIRDSLLPQESEAEATAAFTR-LIESSLSSWFTQVNFFIH 1009
BLAST of pi3k-like protein vs. Ensembl Nematostella
Match: EDO42545 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S165]) HSP 1 Score: 139.043 bits (349), Expect = 4.095e-33 Identity = 126/476 (26.47%), Postives = 226/476 (47.48%), Query Frame = 3
Query: 1884 QFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEM-------HNESI--------------------KIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSS----LLNLSEKQGNII-VETCDVKKS-KKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKI 3200
Q+A++ L++ ++ I +Y+ QLVQA +Y++ F ++ +++ +A ++ L + W +K+ M H +S + ++ E F + N VI+P G E+ R L R + L + L+ D + T ++ L K+ I +E+ +VKK EN +++ + +I FK GDD+RQD+L LQ++S+F I+++ D+ L PY +AT G+IE V D+K+ + R + + Y + + F +A F +S A YS+ +F+L I+DRH N+M++ +G + HIDFG + + G N P + + I G+ ++S F FM LC K+YL +R + +++L ++M+D+GLP + + L+ LR S EK A Y ++ D+Y N+ T++
Sbjct: 1219 QYAIRVLQSFPPDS-ILIYIPQLVQATRYDALGF--VTEYIIWAAQHSQLLAHQLIWNMKTNMFVDEEGLHKDSQIGDHLDQLIGRITSTVSGPERDFYTREFEFFDK-VTNISAVIKPFPKGPERKEACLRALGDIRAEKGVYLPSNPEAMVLEIDQTSGTPMQSAAKAPFLAKFKVKRMGIAELESINVKKDFPCDSDEANQENPNVYWQAAI------FKVGDDVRQDMLALQVISLFKNIFEQVGLDVYLKPYRVVATSPGCGVIECVPDSKSRDQLGRQTEVDLYE------YYLKTYGDESTPAFQQARSNFIKSMAAYSIVSFLLQIKDRHNGNLMLDREGHIIHIDFGFMFESSP---GGNLGFEPDMKISHEMVMIMGGT---MESPPFRWFMDLCVKSYLAVRPYQEALVSLVALMLDTGLPCF-RGETLKRLRARFSPAQSEKEAATYMSKVIRDSYL-NYRTRV 1670
BLAST of pi3k-like protein vs. Ensembl Nematostella
Match: EDO45547 (Phosphatidylinositol 3-kinase [Source:UniProtKB/TrEMBL;Acc:A7RSD9]) HSP 1 Score: 125.176 bits (313), Expect = 4.051e-29 Identity = 112/409 (27.38%), Postives = 188/409 (45.97%), Query Frame = 3
Query: 1947 QLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFL----KSEMHNESIKIYFALMLE---AFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLST--------LKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFA-----KALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELT--------KVQD 3089
Q + +K S DL+ FL+ A ++ + F+W+L K + ++ +Y +M + A +G ++ +R +G ++ I I++ +E Q S L+E L D E + L L + V + KS P L F + + IFK GDDLRQD L LQ++ + D + ++ D+KL PY LAT G+++ ++ SN +A + S+ + + + CE + ++T+ +SCAGY V T++LG+ DRH DN+++ G LFHIDFG+IL R+ P K + +G + + F C A+L LR H++LIL L+ +M+D+ +P++ KVQD
Sbjct: 460 QELDEVKSSSLKTADLASFLITRACKSDTVANYFYWYLLVECKEDKDSKVANMYRNIMRKFSKALMKG--SWECKVRRNMLGKQQQF-IDHIVRLMKEVSQFSGNRSRKIHRLRELL---DTPELTRFGPLPLPLDPDVRIMEVVKAWLFKSHLMPAKL------TFRDINEQEYVVIFKNGDDLRQDQLILQMIRLMDKLLMKENLDLKLTPYKVLATSASHGLVQFIE----------SNAVAEVLDKDGSIQNYFR-KHAPCETGPNGISPEVMDTYVKSCAGYCVITYLLGVGDRHLDNLLLTKSGNLFHIDFGYIL---------GRDPKPLPPPMKLSKEMVEGMGG-ANGECYQAFRKQCYTAFLHLRRHANLILNLFGLMVDASVPDIALEPDKTVKKVQD 835 HSP 2 Score: 52.373 bits (124), Expect = 1.196e-6 Identity = 42/149 (28.19%), Postives = 64/149 (42.95%), Query Frame = 3
Query: 1107 RRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEK-TERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYF---NPGGSTDSYKNRNSV 1541
+R RQ + LL + L E S LYV ++ P S S WNE L I Y ++PRNA+L F++ + R V G +++F +G L G DL +WP ++ +G PG +T + N +
Sbjct: 32 KRDRQGHKELLDDPLLRYSGLYQSECSDLYVTCTIYADDRPLSLPTGTSYRPFSTRWNWNEWLKLPIKYPDLPRNAQLAFTIWDVYGPRKSTPV--GGTTVSLFGKYGTLRHGMHDLKVWP--GVEADGKMPTSTPGKTTATEDQMNRL 176
BLAST of pi3k-like protein vs. Ensembl Nematostella
Match: EDO27738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8E9]) HSP 1 Score: 80.4925 bits (197), Expect = 3.410e-16 Identity = 69/227 (30.40%), Postives = 98/227 (43.17%), Query Frame = 3
Query: 2433 IFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELT--------KVQD 3089
IFK GDDLRQD L LQ++ + D + R F PY A GK R ++ K L T S +GY V T++LG+ DRH DN+++ G LFHIDFG+IL R+ P K + +G + + F C A+L LR H++LIL L+ +M+D+ +P++ KVQD
Sbjct: 108 IFKNGDDLRQDQLILQMIRLMDKV--RIFG-----PYS--ACGK---------------------------------IRSTFSDFAPPPPQEKILGTGLLSVSGYCVITYLLGVGDRHLDNLLLTKSGNLFHIDFGYIL---------GRDPKPLPPPMKLSKEMVEGMGGA-NGECYQAFRKQCYTAFLHLRRHANLILNLFGLMVDASVPDIALEPDKTVKKVQD 282
BLAST of pi3k-like protein vs. Ensembl Medaka
Match: pik3ca (phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [Source:NCBI gene;Acc:101168152]) HSP 1 Score: 619.387 bits (1596), Expect = 0.000e+0 Identity = 379/1058 (35.82%), Postives = 592/1058 (55.95%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIG-----FNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQI---LQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSL-LLISAQLIC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSI-----------------------NISK---VNYYYQEQSPVRIMGSPISTTI-QRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L +K L KE + +Y LL SSYIF V ++AE EE+YDE++ LC+L L L +E GN +E L+ I IG F+L P+ + R++ L V K+ + N P+ ++ Y + E +T R I L + + +I S + K + IS + V E + + KK + E KY+LKV D YLL + Y YV+SC+ P L L ++ L + + F +P Y + T + S ++++ ++ +++C ++ K+YVR +++G ++ + V +P WNE L++D+Y IPR A+LC S+ K +G E L W NIN+F+Y L+ G + LNLWP ++ NP G T S N+ + L + NIS+ NY + S +P++ ++++ + +RD L E++EQ+ D+L + +C+ +PE LP++ +++WN+ EV Y LL WP I E +++LL NF D ++R+FAVK L LT+ ++ YL+QLVQ LKYE Y N L+ FLL+ AL N+++G FFW LKSEMHN+++ F L+LE++CR ++ + Q +EKL+ ++ +LK +++D +Q+ L E ++ D+ + ++ +S LN + + GN+ +E C + S KRP++L WEN D+ SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+++ T+M IQ + + A+Q NS +L++WI+ N+ E + +A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ G+ + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL+++ E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 IVVDCLLPNGMILSLECLREATLVTVKHELFKEARKYPLYH--LLQEESSYIFVSVTQEAEREEFYDETRRLCDLRLFQAFLKVIEPVGNREEKILSREIGFAIGMPICEFDLVKDPEVQ---------DFRRNILNVCKEAVDLRDNNGPHSRALYVYPPNV-ESSTDLPRHIYNKLDKGQIIVVIWVIISPSNDKQKYTLKISHD-CVPEQVIAEAIRKKTRSMLLSQEQLKMCVQEYQGKYILKVCGCDEYLLEKY-PLSQYKYVRSCIMLGRMPNLMLMSKDSLYSQLPSDNFTMPSYARRISTATSYMNGETSSKNLWTINGMLKIRILCATYVNVNIRDIDKIYVRTGIYHG-GEQLCDNVNTLRVPCSNPRWNEWLSYDMYILEIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTHTLVAGKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFEQFSSPVKFPDMAYVEEHANWNISRELGFNYSHTGLSNRLARDNPLTDNDNEQLRQVCNRDPLSEITEQEKDFLWRHRHSCINIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNFPDPMIREFAVKCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDLLKQEKKDEAQKVQMKFLVEQMRRPDYMDALQSFTSPLNPAHQLGNLRLEECRMMSSAKRPLWLNWENPDMMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWIKDKNKG-EMYDQAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKEDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKSEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Medaka
Match: PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:101161626]) HSP 1 Score: 612.453 bits (1578), Expect = 0.000e+0 Identity = 383/1055 (36.30%), Postives = 581/1055 (55.07%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSM-TCLYITTLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQL----IC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINI----SKVNY-------YYQEQSPVRIMGSPISTTIQ----------------RIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL + YIF V ++AE EE+YDE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K E AN P+ ++ Y + E + + I + I + S N K T+ V E + + KK + E KY+LKV L I Y Y++SC+ P L L ++ L + + F++P Y + I ++ K SL IS L +C ++ K+YVR +++G ++ + V +P WNE LN+D+Y +IPR A+LC S+ K +G E L W NIN+F+Y L+ + LNLWP ++ NP G T S N+ + L + S V Y + + R +G +T+ Q ++K + +RD L E++EQ+ D+L + C+ +PE LP++ +++WN+ EV Y LL +WP I E +++LL N+ D ++R FAV+ L L + ++ YL+QLVQ LKYE Y N L+ FLL+ AL N+++G FFW LKSEMHN+++ F L+LEA+CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E +K D+ + +N +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS++L++W++ NR E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ GS + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL++E E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNV-ESSQDLPKHIYSKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKV-CGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTDSFVMPSYC-RRISTATSYMNGEAAPK--SLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYNHTLVANKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFEHFSSPVKYPDMNAVEEHANWTISRELGFNYNTSGQSNRVARDHALTDSDSEQLKQLSNRDPLSEITEQEKDFLWRHRHYCMNIPEILPKILLAVKWNSRDEVAQMYCLLKEWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRG-EMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1060
BLAST of pi3k-like protein vs. Ensembl Medaka
Match: PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [Source:NCBI gene;Acc:101161626]) HSP 1 Score: 570.466 bits (1469), Expect = 0.000e+0 Identity = 368/1032 (35.66%), Postives = 557/1032 (53.97%), Query Frame = 3
Query: 204 VTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIAN-PNDIVIFQYGADYNEFTTSTARQILQSMTCLYIT-----TLISYKSVNPFKCVVTIS-KEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYL-ENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQL----IC--------KENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIE-KTERGGNE--VLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQRED----LQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ-RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+ V LLPN + R+A+L IK L KE + ++ LL + YIF V ++AE EE+YDE++ LC+L L L +E GN +E ++N IGF + E+ + D E+ + R++ L V K E AN P+ ++ Y + E + + I + ++T + S N K T+ V E + + KK + E KY+LKV L I Y Y++SC+ P L L ++ L + + F++P Y + I ++ K SL IS L +C ++ K+YVR +++G ++ + V +P WNE LN+D+Y +IPR A+LC S+ K +G E L W NIN+F+Y L+ + LNLWP ++ NP G T S N+ + L + + SPV+ ++ + I R E +Y S N R+A+ + +T+ + KWP I E +++LL N+ D ++R FAV+ L L + ++ YL+QLVQ LKYE Y N L+ FLL+ AL N+++G FFW LKSEMHN+++ F L+LEA+CR ++ + Q +EKL+ ++ ILK +++D +Q+ L E +K D+ + +N +S LN + + GN+ +E C + S KRP++L WEN DI SE + IFK GDDLRQD+LTLQ++ I + IW+ Q D+++LPYGCL+ G G+IE V+ + T+M IQ + + A+Q NS++L++W++ NR E + A++ FTRSCAGY VATFILGI DRH NIMV GQLFHIDFGH L+++KKKFG RERVPFVLT+DF+ I+ GS + +F F +C KAYL +R+H++L + L+S+M+ SG+PEL D+ Y+RKTL++E E+ AL+YF +Q DA+ G WTTK+DW+ H
Sbjct: 20 ILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHH--LLQEETCYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREE----KILNREIGFAIGMPVCEFDLVKDFEVQDFRRNILNVCKDAVELRDANGPHSRALYVYPPNV-ESSQDLPKHIYSKLDKGWVTGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSPEQLKMCVQEYQGKYILKV-CGCDEYLLEKYPISQYKYIRSCIMLGRLPNLMLMAKDSLYSQLPTDSFVMPSYC-RRISTATSYMNGEAAPK--SLWTISGGLRIRILCATYVNVNIRDIDKIYVRTGIYHG-GEQMCDNVNTQRVPCSNPRWNEWLNYDMYILDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYNHTLVANKMALNLWPVPHGLED-LLNPIGVTGSNPNKETPCLELEFEHFS------SPVKY--PDMNAVEEHANWTISR-------ELGFNYNTSGQSN---------RVARD---HALTDSDSEQLKQLKWPSIRPEQAMELLDCNYPDPMVRHFAVRCLDKFLADDKLSQYLIQLVQVLKYEQYLDNPLARFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLEAYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMRFLVEQMKRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSEMLFQNNEIIFKNGDDLRQDMLTLQIIKIMENIWQNQGLDLRMLPYGCLSLGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSNTLHQWLKDKNRG-EMYDMAVDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGSQECTKTKEFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALEKGEQEALDYFMKQMNDAHHGGWTTKMDWIFH 1010
BLAST of pi3k-like protein vs. Ensembl Medaka
Match: pik3cb (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:NCBI gene;Acc:101165660]) HSP 1 Score: 446.047 bits (1146), Expect = 1.622e-138 Identity = 290/818 (35.45%), Postives = 450/818 (55.01%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFPILSLYPREYL------ENISINRFI-------IPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLI-CKENSKLYVRVAMFNGINTRIAPEQKS-SLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL---IEKTER-----------------GGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGST--DSYKNRNSVILSINISKVNYYYQEQSP--------VRIMGSPISTTIQR--------IKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----------LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I Y Y++SCL E P L+L + EN +I + P + T+ +T VS+ F ++L+ + EN+K+ VR +F+G P S S S+H N L F+I ++PR +LCF++ +EK ++ G + W N +F+Y G+L G + L+ W + NP G+ + Y N+ L I+ + P I GS ST I R +K I++RD L +L E + D + + +C P+SLP+L S++W+ ++ +LL WP+++ +L+LL N+ D+ +R++AV LR +++ ++ YLLQLVQ L+YE YY L+ FLL+ A +N+++G FW L+SE+H ++ I FAL+LEA+CRG + + V++ Q + KL ++ ++K S KE LK ++E ++ S LN + +I VE C SK +P+++ + N + S+ TL IFK GDDLRQD+LTLQ+L + D +WK D++++PYGCLATG +G+IE V A T+ +IQ SN+ AA N +L W++ N + + +A+E FT SCAGY VAT++LGI DRH DNIMV + GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + KF F C +AYL LR++ +L +TL+++M+ +GLPELT V+D++YL+ +L++ ++ AL F ++F +A R +WTTK++W++H
Sbjct: 262 LIQYKYIRSCLQAKESPHLTLVHINAVKTIFDKENAAIGAVVSRKSSNPPLPLPPKKRAPTQVQTCVWDVSRPFKVVLVKGSTVNADENAKVQVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPE-NATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLRD-MSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDINVEKCRYMDSKMKPLWIVYNNKLMSSD----TLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERN-SGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTE--KFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAH 1070
BLAST of pi3k-like protein vs. Ensembl Medaka
Match: pik3cb (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [Source:NCBI gene;Acc:101165660]) HSP 1 Score: 435.261 bits (1118), Expect = 1.075e-134 Identity = 282/804 (35.07%), Postives = 437/804 (54.35%), Query Frame = 3
Query: 960 IIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKS-SLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL---IEKTER-----------------GGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGST--DSYKNRNSVILSINISKVNYYYQEQSP--------VRIMGSPISTTIQR--------IKAIIDRDWLYELSEQDIDYLRSNLENCLW-VPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEY----------LKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQ--RSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
+I Y Y++SCL E P L+L ++ I + +N +R+ S + A + VR +F+G P S S S+H N L F+I ++PR +LCF++ +EK ++ G + W N +F+Y G+L G + L+ W + NP G+ + Y N+ L I+ + P I GS ST I R +K I++RD L +L E + D + + +C P+SLP+L S++W+ ++ +LL WP+++ +L+LL N+ D+ +R++AV LR +++ ++ YLLQLVQ L+YE YY L+ FLL+ A +N+++G FW L+SE+H ++ I FAL+LEA+CRG + + V++ Q + KL ++ ++K S KE LK ++E ++ S LN + +I VE C SK +P+++ + N + S+ TL IFK GDDLRQD+LTLQ+L + D +WK D++++PYGCLATG +G+IE V A T+ +IQ SN+ AA N +L W++ N + + +A+E FT SCAGY VAT++LGI DRH DNIMV + GQLFHIDFGHIL N K KFG+ RERVPF+LT DFI I G + KF F C +AYL LR++ +L +TL+++M+ +GLPELT V+D++YL+ +L++ ++ AL F ++F +A R +WTTK++W++H
Sbjct: 262 LIQYKYIRSCLQAKESPHLTLVHINAVKTI---------FDKENAAIGAVVSRKSSNPPLPLPPKKRAPTV-------QVRAGLFHGTELLCKPAVSSESSGRSNHSLENNTLEFEISVCDLPRMTRLCFAIYAIMEKVKKKSYKNPHINKYQTIRKAGKVHYPIAWVNTMVFDYKGQLKTGDMILHCWSSFPDELEEMLNPIGTVRINPYPE-NATALHIHFPDYGPHPIVFPPFDKILEKAAEIAGSSDSTPIGRGGKKFHIELKEIMERDPLSQLCENEKDLIWTLRLDCRENFPQSLPKLLLSVKWSKHEDMAQLQALLQIWPKLSPRDALELLDFNYPDQYVREYAVSCLRD-MSDEELLQYLLQLVQVLRYEPYYDCALTHFLLERAQKNRKIGHFLFWHLRSEIHMPAVSIQFALILEAYCRGSIPHIEVLKKQVEALSKLKSVNELIKLGTIKNTRSKTKEAMLTKEAMITCLKQSGYSEALSDLHSPLNPNVLLSDINVEKCRYMDSKMKPLWIVYNNKLMSSD----TLGIIFKNGDDLRQDMLTLQILRLMDLLWKEANLDLRIVPYGCLATGDRAGLIEVVSSADTIANIQLTSSNVAAAAAFNKDALLNWLKERN-SGDALERAIEEFTLSCAGYCVATYVLGIGDRHSDNIMVRSTGQLFHIDFGHILGNFKSKFGIKRERVPFILTHDFIHVIQQGKTGYTE--KFGSFRQYCEEAYLVLRKNGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSDEEALKQFRQKFDEALRESWTTKVNWMAH 1040
BLAST of pi3k-like protein vs. Planmine SMEST
Match: SMESG000011425.1 (SMESG000011425.1) HSP 1 Score: 2027.68 bits (5252), Expect = 0.000e+0 Identity = 1017/1023 (99.41%), Postives = 1022/1023 (99.90%), Query Frame = 3
Query: 150 MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSIYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVINHCIGFNLDNLPKXXXXXXXXXXXNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVXXXXXXXXXXXXKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFSLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISTTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 3218
MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNS+YEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVI+HCIG NLDNLPKEYYELYDLELLNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVSSLDSYLLNLNDKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMF+LLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPIS+TIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVI+PQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF
Sbjct: 1 MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKELKTNSVYEELLLNNFSSYIFCGVNRDAEIEEYYDESQLLCNLNLIDFVLNCLERKGNEDESQLTSVISHCIGLNLDNLPKEYYELYDLELLNARKSYLEVVKKEHESLIANPNDIVIFQYGADYNEFTTSTARQILQSMTCLYITTLISYKSVNPFKCVVTISKEFTVKETIFKILLDKKDSFEFDGSMDPNIWASENSIKYVLKVSSLDSYLLNLNDKIIFYDYVQSCLYNNEFPILSLYPREYLENISINRFIIPPYFYQNIPQTKRRTRQDSVSKMFTLLLISAQLICKENSKLYVRVAMFNGINTRIAPEQKSSLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSLIEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINISKVNYYYQEQSPVRIMGSPISSTIQRIKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPRINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHNESIKIYFALMLEAFCRGYLNFMTVIKPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSHF 1023
BLAST of pi3k-like protein vs. Planmine SMEST
Match: SMESG000012105.1 (SMESG000012105.1) HSP 1 Score: 282.722 bits (722), Expect = 1.939e-79 Identity = 213/723 (29.46%), Postives = 366/723 (50.62%), Query Frame = 3
Query: 1179 ENSKLYVRVAMFNGINTRIAPEQKS-SLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL--------IEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSV--ILSIN-ISKVNYY----YQEQSPVRIMGSPI---------STTIQR--IKAIIDRDWLYE-LSEQDI-----DYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWP-RINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN-ESIKIYFALMLEAF-------CRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKK--KFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
++ K+ + +F+G + P+ + SL S P + F + N+PR + CF+L ++ + +GW N I+++ G L I LW ++ N NP GS S + + +L+I + K++ + Y + + + G + ST ++ IK + D+ + + EQ+I Y+R+ + +SLP++ S WN+ +++ + ++ WP ++ +L+LL NF D R AV +L I +I+LYLLQ+ Q LKYESY ++ +LL+ + N ++ Q F+F+K E+ E K+ FA +L + C L + + L++++ L+ +R++ L + L++D+ ++ L+ + K + C SK RPI L W+ + +EF+ + I+K GDDLRQD L LQ++ I D IW+R+ D+KL PY LA K G I+ VK+A+T+ +I R+ S + W++ N T ++ ++ FTRS A Y VATFILGI DRH DNIM+ G FHIDFGHIL N K+ + V+RE F+L ++F+ + D F LC Y+ +R+HS+LI +L+ M+++G+PE++ ++DL YL++TL + ++ A +YF + D + ++W +H
Sbjct: 391 KDQKIVIVAGLFHGGKSLCEPQYREWSLDSLCCP-----IVFTLPLWNLPRMTRFCFALAVVKQTLPLKDIANNTQKKFIGWGNTMIYDHKGILKSDEIRYRLW--SSVKPN--LNPTGSVYSNPDGQLIAPLLAIQFVPKLSKFKKIVYPAKEKLILEGGYLFNNAHTNEPSTENEKEDIKKYLQADFSDDAMQEQEILWKYRYYIRNTYQ------DSLPKILNSKPWNSFENISMMHHVMCGWPIDKDIIIALELLGSNFPDCDTRLMAVDSLSRI-DWQEISLYLLQICQCLKYESYLNSNFIQWLLKIMISNAKIAQTIFYFMKVELSTCEWCKVLFATILYNYLHYSRTRCDSLLKQYYATNELGLQNKTLLQLTS-LEGERKNQALQKFRRSLESDESQRLFNELTCPLDCNIKLKTLDASHCKFMDSKMRPIRLTWK---VSTEFATEYM-IIYKNGDDLRQDSLVLQIMHIMDTIWQRKDLDLKLHPYDVLACSKTEGYIQVVKNAETIANISRT----------SKILNWLKEFN-TEKEMEIVVKNFTRSLAAYCVATFILGIGDRHNDNIMLTKNGHFFHIDFGHILGNFKRIMRGMVSREWTKFILVQEFLDVVESEDD----------FRNLCCDGYIAIRDHSNLIFSLFKAMVNAGIPEISSIEDLNYLKETLQIGKGDEEARSYFQNVYADTRKKEVFITMNWGAH 1071
BLAST of pi3k-like protein vs. Planmine SMEST
Match: SMESG000012105.1 (SMESG000012105.1) HSP 1 Score: 282.722 bits (722), Expect = 2.890e-79 Identity = 215/728 (29.53%), Postives = 368/728 (50.55%), Query Frame = 3
Query: 1170 ICKENSKLYVRVAMFNGINTRIAPEQKS-SLVSSDHPTWNEKLNFDIYYSNIPRNAKLCFSL--------IEKTERGGNEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRN----SVILSIN-ISKVNYY----YQEQSPVRIMGSPI---------STTIQR--IKAIIDRDWLYE-LSEQDI-----DYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWP-RINLESSLQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYESYYFNDLSVFLLQSALRNKQLGQKFFWFLKSEMHN-ESIKIYFALMLEAF-------CRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIYLEWENADIFSEFSIPTLKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKK--KFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMVLCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVESDEKAALNYFNRQFCDAYRGNWTTKIDWLSH 3215
I ++ K+ + +F+G + P+ + SL S P + F + N+PR + CF+L ++ + +GW N I+++ G L I LW ++ N NP GS Y N + + +L+I + K++ + Y + + + G + ST ++ IK + D+ + + EQ+I Y+R+ + +SLP++ S WN+ +++ + ++ WP ++ +L+LL NF D R AV +L I +I+LYLLQ+ Q LKYESY ++ +LL+ + N ++ Q F+F+K E+ E K+ FA +L + C L + + L++++ L+ +R++ L + L++D+ ++ L+ + K + C SK RPI L W+ + +EF+ + I+K GDDLRQD L LQ++ I D IW+R+ D+KL PY LA K G I+ VK+A+T+ +I R+ S + W++ N T ++ ++ FTRS A Y VATFILGI DRH DNIM+ G FHIDFGHIL N K+ + V+RE F+L ++F+ + D F LC Y+ +R+HS+LI +L+ M+++G+PE++ ++DL YL++TL + ++ A +YF + D + ++W +H
Sbjct: 405 IILKDQKIVIVAGLFHGGKSLCEPQYREWSLDSLCCP-----IVFTLPLWNLPRMTRFCFALAVVKQTLPLKDIANNTQKKFIGWGNTMIYDHKGILKSDEIRYRLW--SSVKPN--LNPTGSV--YSNPDGQLIAPLLAIQFVPKLSKFKKIVYPAKEKLILEGGYLFNNAHTNEPSTENEKEDIKKYLQADFSDDAMQEQEILWKYRYYIRNTYQ------DSLPKILNSKPWNSFENISMMHHVMCGWPIDKDIIIALELLGSNFPDCDTRLMAVDSLSRI-DWQEISLYLLQICQCLKYESYLNSNFIQWLLKIMISNAKIAQTIFYFMKVELSTCEWCKVLFATILYNYLHYSRTRCDSLLKQYYATNELGLQNKTLLQLTS-LEGERKNQALQKFRRSLESDESQRLFNELTCPLDCNIKLKTLDASHCKFMDSKMRPIRLTWK---VSTEFATEYM-IIYKNGDDLRQDSLVLQIMHIMDTIWQRKDLDLKLHPYDVLACSKTEGYIQVVKNAETIANISRT----------SKILNWLKEFN-TEKEMEIVVKNFTRSLAAYCVATFILGIGDRHNDNIMLTKNGHFFHIDFGHILGNFKRIMRGMVSREWTKFILVQEFLDVVESEDD----------FRNLCCDGYIAIRDHSNLIFSLFKAMVNAGIPEISSIEDLNYLKETLQIGKGDEEARSYFQNVYADTRKKEVFITMNWGAH 1088
BLAST of pi3k-like protein vs. Planmine SMEST
Match: SMESG000073245.1 (SMESG000073245.1) HSP 1 Score: 187.578 bits (475), Expect = 6.798e-48 Identity = 178/683 (26.06%), Postives = 314/683 (45.97%), Query Frame = 3
Query: 1248 KSSLVSSDHPTWNEKLNFD--IYYSNIPRN---AKLCFSL------IEKTERGG-NEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINIS--KVNYYYQEQSPVRIMGSPISTTIQR----IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWP-RINLESSLQLLSGNFFDK-------VLRQFAVKNLRAILTNADINLYLLQLVQALKYE-SYYFNDLSVFLLQSALRNKQLGQKFFWFLKS----EMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIY--------LEWENADIFSEFSIPT-----------LKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMV-LCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVE-SDEKAA 3140
+ S+ + HP + + + F+ I + N+ N + C S+ I ++ +E L+GW + +F+ G L +G + + LW + S S + + + +L I + + Y S ++I P Q+ ++ I+ WL D + N+ + LW + L S R + L SL+S WP I ++ LLS + D+ +R++AV+ L+ I ++ I++ + LV+ALKY+ + + L LL ++ N FW L S ++H + +++ + + ++K E + K D ++ TL N+ L +L KQ + D R Y LE ++ F+ F++P + +FK GDDLRQDIL LQL + D IW + +++++ Y + TG SG++E V D T+ IQ S IAA + S + W++ N T + K++ F +CA Y V+T++LGI DRH DNIM+ T G +FHIDF IL + + G+ R+RVPFVLT+D + + D P D + ++ C +AY +R H + ++++ S+ + +P + + ++Y+ K L ++ SD +A+
Sbjct: 528 QESIATKIHPKFPKCITFNATISFDNLSMNYLTMETCLSIEVFGRRISSSDSPKISEELIGWTEMALFDSAGMLKQGKMLIGLWV-------NHRKLKSSHGSNRQKAAPVLQIELPDFHIPVKYICDSSLKINEIPYLKPTQKESNLLEKFINNMWL-----DSNDKVAQNVCDMLW--KHRGHLLDSPR----KYIALCLSLVSLWPNEIQSDNKDFLLS--YLDRWPHMPLIKIRRWAVEALQKIGPDSCISI-IPWLVEALKYDLNLNSSGLENLLLDFSIMNINFATNLFWQLNSINATDIHGYDAILLLGMLMSLVNNAIFDMWNLQLEMVNHLKKTAESVKAYKGSTIDRKI-TLH------------TNLEELYDLISKQKQSQADEGDHPLCTYRIPYHPGLAIHKLEMKDCSYFNSFTLPLRIVFKGIDEILFEVMFKSGDDLRQDILVLQLFKLMDDIWTNEGLNLRMVHYQVMNTGVRSGLVELVGDCTTLRKIQESKGIAAPLTSISGISEWLKCQNTTKAAYIKSVNNFLLTCAAYCVSTYLLGIGDRHNDNIMIQTSGCIFHIDFAKILGDAQTFAGIRRDRVPFVLTQDMVHVLEDYQPHPDDRRTGMQLLIDKCCEAYNIIRRHWTSLISVLSMAAAANIPGVNN-KTIQYVVKMLRLDYSDIQAS 1175
BLAST of pi3k-like protein vs. Planmine SMEST
Match: SMESG000073245.1 (SMESG000073245.1) HSP 1 Score: 184.496 bits (467), Expect = 6.619e-47 Identity = 179/698 (25.64%), Postives = 313/698 (44.84%), Query Frame = 3
Query: 1248 KSSLVSSDHPTWNEKLNFD--IYYSNIPRN---AKLCFSL------IEKTERGG-NEVLLGWANINIFNYFGKLIEGSIDLNLWPFEKIQDNGYFNPGGSTDSYKNRNSVILSINIS--KVNYYYQEQSPVRIMGSPISTTIQR----IKAIIDRDWLYELSEQDIDYLRSNLENCLWVPESLPRLAKSIRWNNVTEVNLFYSLLSKWPR------------------INLESS-----LQLLSGNFFDKVLRQFAVKNLRAILTNADINLYLLQLVQALKYE-SYYFNDLSVFLLQSALRNKQLGQKFFWFLKS----EMHNESIKIYFALMLEAFCRGYLNFMTVIRPQSIGIEKLVEISRILKAQREDLQLSTLKEYLKNDDFNETCKNVSSLLNLSEKQGNIIVETCDVKKSKKRPIY--------LEWENADIFSEFSIPT-----------LKFIFKCGDDLRQDILTLQLLSIFDWIWKRQFQDMKLLPYGCLATGKDSGIIEAVKDAKTVMSIQRSNIIAAMQMNSSSLYRWIQANNRTCEQFAKALETFTRSCAGYSVATFILGIRDRHPDNIMVNTKGQLFHIDFGHILNNRKKKFGVNRERVPFVLTEDFIKTIADGSDRPLDSVKFNEFMV-LCGKAYLKLREHSSLILTLYSIMIDSGLPELTKVQDLEYLRKTLSVE-SDEKAA 3140
+ S+ + HP + + + F+ I + N+ N + C S+ I ++ +E L+GW + +F+ G L +G + + LW + S S + + + +L I + + Y S ++I P Q+ ++ I+ WL D + N+ + LW + L S R + L SL+S WP NL+ S L LL + +R++AV+ L+ I ++ I++ + LV+ALKY+ + + L LL ++ N FW L S ++H + +++ + + ++K E + K D ++ TL N+ L +L KQ + D R Y LE ++ F+ F++P + +FK GDDLRQDIL LQL + D IW + +++++ Y + TG SG++E V D T+ IQ S IAA + S + W++ N T + K++ F +CA Y V+T++LGI DRH DNIM+ T G +FHIDF IL + + G+ R+RVPFVLT+D + + D P D + ++ C +AY +R H + ++++ S+ + +P + + ++Y+ K L ++ SD +A+
Sbjct: 528 QESIATKIHPKFPKCITFNATISFDNLSMNYLTMETCLSIEVFGRRISSSDSPKISEELIGWTEMALFDSAGMLKQGKMLIGLWV-------NHRKLKSSHGSNRQKAAPVLQIELPDFHIPVKYICDSSLKINEIPYLKPTQKESNLLEKFINNMWL-----DSNDKVAQNVCDMLW--KHRGHLLDSPR----KYIALCLSLVSLWPNEIQSDNKDFLLSYLDRCDFNLKDSSFIEILYLLGPHMPLIKIRRWAVEALQKIGPDSCISI-IPWLVEALKYDLNLNSSGLENLLLDFSIMNINFATNLFWQLNSINATDIHGYDAILLLGMLMSLVNNAIFDMWNLQLEMVNHLKKTAESVKAYKGSTIDRKI-TLH------------TNLEELYDLISKQKQSQADEGDHPLCTYRIPYHPGLAIHKLEMKDCSYFNSFTLPLRIVFKGIDEILFEVMFKSGDDLRQDILVLQLFKLMDDIWTNEGLNLRMVHYQVMNTGVRSGLVELVGDCTTLRKIQESKGIAAPLTSISGISEWLKCQNTTKAAYIKSVNNFLLTCAAYCVSTYLLGIGDRHNDNIMIQTSGCIFHIDFAKILGDAQTFAGIRRDRVPFVLTQDMVHVLEDYQPHPDDRRTGMQLLIDKCCEAYNIIRRHWTSLISVLSMAAAANIPGVNN-KTIQYVVKMLRLDYSDIQAS 1192 The following BLAST results are available for this feature:
BLAST of pi3k-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of pi3k-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of pi3k-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of pi3k-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of pi3k-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025635 ID=SMED30025635|Name=pi3k-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=3274bpback to top protein sequence of SMED30025635-orf-1 >SMED30025635-orf-1 ID=SMED30025635-orf-1|Name=SMED30025635-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1027bp MKRSDVPLNYYTYSFSNDVTVMILLPNFSVEEFVVSRKASLFEIKDILLKback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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