MFS domain-containing protein

Overview
NameMFS domain-containing protein
Smed IDSMED30025634
Length (bp)1861
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of MFS domain-containing protein (SMED30025634) t-SNE clustered cells

Violin plots show distribution of expression levels for MFS domain-containing protein (SMED30025634) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MFS domain-containing protein (SMED30025634) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MFS domain-containing protein (SMED30025634) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025634

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pharynxSMED30025634SMESG000066500.1 dd_Smed_v4_9883_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025634SMESG000066500.1 dd_Smed_v4_9883_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30025634SMESG000066500.1 dd_Smed_v4_9883_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30025634SMESG000066500.1 dd_Smed_v4_9883_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025634SMESG000066500.1 dd_Smed_v4_9883_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 53.5286 bits (127), Expect = 7.802e-7
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 52.7582 bits (125), Expect = 1.356e-6
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 52.7582 bits (125), Expect = 1.356e-6
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 52.7582 bits (125), Expect = 1.356e-6
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 52.7582 bits (125), Expect = 1.356e-6
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: Y53G8AR.7 (pep chromosome:WBcel235:III:3282308:3290215:1 gene:WBGene00021814.1 transcript:Y53G8AR.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y53G8AR.7)

HSP 1 Score: 56.6102 bits (135), Expect = 3.677e-8
Identity = 48/198 (24.24%), Postives = 96/198 (48.48%), Query Frame = 2 
Query:  473 GFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIY-----FVASEP-WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKF---QIGSVSLNIYNSPGFLMAILWCVQTIQVLI----SYPDVDKS 1027
            G   G++ +I  PTLW  F+      A++S++    AAF++   L +P++G+   K    +  LV    + ++ NII+     F   E  W++M+ RF  G+G+G+   + A     ++ ++R   I  +  +  +G+ +GP   +   PI +     G   +++Y SP +  +I+  +  I + I    +Y  +D+ 
Sbjct:   55 GMFCGIQFSIFFPTLWP-FLNTVDPTASASFFGFITAAFSVGQGLASPVFGYWMNKAKSVRQPLVFGISVMILSNIIFCFVEAFAEKERRWVMMVARFFIGVGAGTIGVMRAYAATASSLKDRARAITFIQASYVIGMTLGPGIQVAFTPIGYPGLSKGVFHVDMYTSPAWFASIISLLSVIFIFIFLEENYAGLDQG 251
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: ZK550.2 (pep chromosome:WBcel235:IV:17245584:17249750:1 gene:WBGene00013996.1 transcript:ZK550.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:ZK550.2)

HSP 1 Score: 56.225 bits (134), Expect = 4.268e-8
Identity = 54/213 (25.35%), Postives = 96/213 (45.07%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASE-----PWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPI---KFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGK-NINEMIIHK 1087
            F+ GV+ ++   ++W Y ++     A   +    +AA N+   +  PLYG    K    K   V    +  VG ++Y   SE      W +++ R + G+G G+   L A     +  ++R   I         G+  GPA +    P+    F I  V +N+Y S  +LMA + CV    +++ +   D +G + K+SS  K N + +++ K
Sbjct:   46 FVVGVQISVYYMSMWPY-LSGLDKTADMDFLGWVVAACNMGCTITNPLYGLWNQKTLSCKWPTVTGFLIAAVGQVMYGAISEVEQYGKWYMLVARVVTGLGVGNLAALRAYGATASTPKDRLKAISYGTAGFVFGISFGPAISAFFTPLGETGFNIWIVKINMYTSAAYLMAFI-CVLAAVLMLVFFQEDYAGIIDKNSSDEKCNADYVVVPK 256
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 157.532 bits (397), Expect = 2.101e-41
Identity = 115/423 (27.19%), Postives = 195/423 (46.10%), Query Frame = 2 
Query:  479 LTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINE------MIIHKIYEKNMSDTSSHLNTEIHRDS------DKSKRTFIDNAKKSIHKFS---RYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMS--CGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            L+G+E A+ILPT+W Y       +A   +    L+AF+ S  +  P++G  + K   TK +++ SN  E+VGN +YF+    W+++  R +AGIG+G+   ++  + R T  +ER      ++  RQ GL+IGPA  + L    F++G   +N Y SPG  M  +W +    V+  Y D+    +  +     + +        M +       ++D+   LN E                +   +       FS    +     + LL   F + F   +LE ++ P+T +YF + E+ NS +Y   G  VI  + +++ +SR ++DR VL  GL+    + VW  I L    + +  L   L     G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:   20 LSGIEYAVILPTIWRYLQLL---EAPPYFLGLGLSAFSFSGLVTGPVFGHWSDKTRTTKTIILFSNVFEIVGNFMYFMGYSKWLLLSSRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPLMSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWLSRVLEDRVVLAVGLLICSGACVWCLIFLA---NPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 436
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731])

HSP 1 Score: 154.451 bits (389), Expect = 2.621e-40
Identity = 110/406 (27.09%), Postives = 188/406 (46.31%), Query Frame = 2 
Query:  497 AIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHK-----IYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILY-ISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            A+ILPT+W Y  T     AA  +   +L+AF+ S  L  PL+G  + +   TK +++ +N  E+VGN +YF+    W+++  R +AGIG+G+   ++  + R T  E+R+     ++  RQ GL+IGP   L L    F++G   +N Y +PG  M +LW +  + V+  Y D+          S  +   E    +     +    +S +   ++                     +   S +     + LLA  F + F   +LE ++ P+T ++F++ E+ NS +Y   G  VI  +  ++  S+   +R VL  GLI   IS VW  I L   N      + ++    G+F  + GL  V     SLF+K    +    +Q + R+    + ++GP  AG L
Sbjct:   35 AVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDERRSQRSPEQEEEEEEEEEEAKPLVGPNELSGSYGTIDLMCVCVCVCVCVCVCVCVCVCVFLLSEFLREEVVVLLAAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAERVVLAVGLILCNISCVWCLIFLA--NPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGL 435
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731])

HSP 1 Score: 153.295 bits (386), Expect = 3.743e-40
Identity = 113/403 (28.04%), Postives = 188/403 (46.65%), Query Frame = 2 
Query:  497 AIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEK--NMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILY-ISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            ++ILPT+W Y  T     AA  +   +L+AF+ S  L  PL+G  + +   TK +++ +N  E+VGN +YF+    W+++  R +AGIG+G+   ++  + R T  E+R+     ++  RQ GL+IGP   L L    F++G   +N Y +PG  M +LW +  + V+  Y D+          S  +   E    +  +     ++ S    T     S  S     D    S            + LLA  F + F   +LE ++ P+T ++F++ E+ NS +Y   G  VI  +  ++  S+   +R VL  GLI   IS VW  I L   N      + ++    G+F  + GL  V     SLF+K    +    +Q + R+    + ++GP  AG L
Sbjct:    6 SVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDERRSQRSPEQEEEEEEEEEEAKPLVGPNELSGSYGTVTSIQSRASSMANGDLTCVSPPPSPTPEEEEVVVLLAAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAERVVLAVGLILCNISCVWCLIFLA--NPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGL 403
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 95.1301 bits (235), Expect = 9.375e-21
Identity = 76/301 (25.25%), Postives = 127/301 (42.19%), Query Frame = 2 
Query:  845 LLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINE------MIIHKIYEKNMSDTSSHLNTEIHRDS------DKSKRTFIDNAKKSIHKFS---RYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMS--CGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            +  RQ GL+IGPA  + L    F++G   +N Y SPG  M  +W +    V+  Y D+    +  +     + +        M +       ++D+   LN E                +   +       FS    +     + LL   F + F   +LE ++ P+T +YF + E+ NS +Y   G  VI  + +++ +SR ++DR VL  GL+    + VW  I L    + +  L   L     G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:    1 MACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPLMSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWLSRVLEDRVVLAVGLLICSGACVWCLIFLA---NPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 298
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 67.0106 bits (162), Expect = 1.398e-11
Identity = 48/156 (30.77%), Postives = 77/156 (49.36%), Query Frame = 2 
Query: 1235 LLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMS--CGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            LL   F + F   +LE ++ P+T +YF + E+ NS +Y   G  VI  + +++ +SR ++DR VL  GL+    + VW  I L    + +  L   L     G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:  126 LLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWLSRVLEDRVVLAVGLLICSGACVWCLIFLA---NPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 278
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 174.866 bits (442), Expect = 3.163e-47
Identity = 118/429 (27.51%), Postives = 205/429 (47.79%), Query Frame = 2 
Query:  479 LTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDV---------DKSGALLKSSSQGK----------NINEMIIHKIYEKNMSD---TSSHLNTEIHRDSDKSKRTFIDNAKKSIH-KFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            L G+E A+ILPT+W+Y  +     A   +    L+A + +  L  PL+G+ + +  +TK ++++SN  E+ GN++YFV    W ++  R +AG+GSG+   ++  + R ++ +ER + + + +  RQVGL+IGPA  + L    FQIG   ++ +++PG  M  LW +    VL  + D+         ++   LL     G           N N +  H  +  +M D   TSS    +IH    K      D  KKS++ + S       + LL   F   F   +LE ++ P+   Y  + ++ NS +Y   G  ++I + +++++ R   DR +L+ GL    IS +W  + +     S  +L    +  G+F  + GL  V AC  SLF+K            + R+    + ++GP  A  L
Sbjct:   37 LNGIEYAVILPTIWMYLQSL---DAEPVFLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEP-EDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRALGRCTSDRLLLIFGLFVCNISCIWCLVFMAKPRGSYGLLLAEFV-VGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGPLWAAGL 460
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 174.481 bits (441), Expect = 3.510e-47
Identity = 118/429 (27.51%), Postives = 205/429 (47.79%), Query Frame = 2 
Query:  479 LTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDV---------DKSGALLKSSSQGK----------NINEMIIHKIYEKNMSD---TSSHLNTEIHRDSDKSKRTFIDNAKKSIH-KFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            L G+E A+ILPT+W+Y  +     A   +    L+A + +  L  PL+G+ + +  +TK ++++SN  E+ GN++YFV    W ++  R +AG+GSG+   ++  + R ++ +ER + + + +  RQVGL+IGPA  + L    FQIG   ++ +++PG  M  LW +    VL  + D+         ++   LL     G           N N +  H  +  +M D   TSS    +IH    K      D  KKS++ + S       + LL   F   F   +LE ++ P+   Y  + ++ NS +Y   G  ++I + +++++ R   DR +L+ GL    IS +W  + +     S  +L    +  G+F  + GL  V AC  SLF+K            + R+    + ++GP  A  L
Sbjct:   28 LNGIEYAVILPTIWMYLQSL---DAEPVFLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEP-EDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRALGRCTSDRLLLIFGLFVCNISCIWCLVFMAKPRGSYGLLLAEFV-VGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGPLWAAGL 451
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 167.933 bits (424), Expect = 6.763e-45
Identity = 115/425 (27.06%), Postives = 200/425 (47.06%), Query Frame = 2 
Query:  497 AIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDV---------DKSGALLKSSSQGK----------NINEMIIHKIYEKNMSD---TSSHLNTEIHRDSDKSKRTFIDNAKKSIHKF---SRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            A+ILPT+W+Y  +     A   +    L+A + +  L  PL+G+ + +  +TK ++++SN  E+ GN++YFV    W ++  R +AG+GSG+   ++  + R ++ +ER + + + +  RQVGL+IGPA  + L    FQIG   ++ +++PG  M  LW +    VL  + D+         ++   LL     G           N N +  H  +  +M D   TSS    +IH    K      D  KKS++      R      + LL   F   F   +LE ++ P+   Y  + ++ NS +Y   G  ++I + +++++ R   DR +L+ GL    IS +W  + +     S  +L    +  G+F  + GL  V AC  SLF+K            + R+    + ++GP  A  L
Sbjct:   26 AVILPTIWMYLQSL---DAEPVFLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEP-EDLGKKSLNDRLSGKRLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRALGRCTSDRLLLIFGLFVCNISCIWCLVFMAKPRGSYGLLLAEFV-VGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGPLWAAGL 445
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784])

HSP 1 Score: 55.0694 bits (131), Expect = 2.764e-7
Identity = 76/343 (22.16%), Postives = 147/343 (42.86%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPI---KFQIGSVSL--NIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEV----HNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISY 1462
            FL+ V  +I++ ++W Y + K    A +S+    +A+F+L   + +PL+G  +    R + L V+S  + V  + +Y     P     + +++ R + G GSG+   + + V   T+  ERT  +  +   + +G I+GPA    L  I      IG++ L  N+Y +P  +                      GALL         N ++I  ++ ++  D     +  IH  S  S+    D  K +     + A  ++  L  +V    F     E +  P+T+  + W       +N  +  A G   +I++  ++ +S+   +R +LL GL+ +   +
Sbjct:   45 FLSSVGFSIVMTSIWPY-LQKVDQSADASFLGWVIASFSLGQMVASPLFGLWSNHRPRREPL-VVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALM----------------------GALLGIG------NIILIFAVFREHRVD-----DLGIHVSSINSESEVTDVEKANEGSIDQIAVISSNILFFVVL---FVFAIFETISTPLTMDMYAWTRTQAVFYNGIILAAVGVESVIVFLAVKILSKKTGERVLLLGGLVIIWFGF 349
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784])

HSP 1 Score: 51.6026 bits (122), Expect = 3.122e-6
Identity = 78/352 (22.16%), Postives = 149/352 (42.33%), Query Frame = 2 
Query:  449 ISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPI---KFQIGSVSL--NIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEV----HNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISY 1462
            IS+ C    F T    +I++ ++W Y + K    A +S+    +A+F+L   + +PL+G  +    R + L V+S  + V  + +Y     P     + +++ R + G GSG+   + + V   T+  ERT  +  +   + +G I+GPA    L  I      IG++ L  N+Y +P  +                      GALL         N ++I  ++ ++  D     +  IH  S  S+    D  K +     + A  ++  L  +V    F     E +  P+T+  + W       +N  +  A G   +I++  ++ +S+   +R +LL GL+ +   +
Sbjct:    3 ISLIC----FCTFSGFSIVMTSIWPY-LQKVDQSADASFLGWVIASFSLGQMVASPLFGLWSNHRPRREPL-VVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALM----------------------GALLGIG------NIILIFAVFREHRVD-----DLGIHVSSINSESEVTDVEKANEGSIDQIAVISSNILFFVVL---FVFAIFETISTPLTMDMYAWTRTQAVFYNGIILAAVGVESVIVFLAVKILSKKTGERVLLLGGLVIIWFGF 312
[Close]
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GPQ3|MFSD8_XENLA (Major facilitator superfamily domain-containing protein 8 OS=Xenopus laevis OX=8355 GN=mfsd8 PE=2 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 3.252e-6
Identity = 81/369 (21.95%), Postives = 157/369 (42.55%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGP---AATLILHPIKFQIGSVSL--NIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEV----HNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGI 1540
            FL+ V  +I++ ++W Y + K    A +S+    +A+F+L   + +PL+G  +    R + L V+S  + V  + +Y     P     + +++ R   G GSG+   + + V   T+  ERT  +  +   + +G I+GP   AA  ++      I  +SL  N+Y +P  + A+L     I +   + +                ++++      EKN+S  +S   +E+  D +K+    ID                 +S   + F   F     E +  P+T+  + W       +N  +  A G   +I++  ++ + +   +R +LL GL  + I +    I+L   N   KI +  L +  I
Sbjct:   45 FLSSVGFSIVMTSIWPY-LQKVDQSADASFLGWVIASFSLGQMVASPLFGLWSNHRPRREPL-VVSITILVAASCLYAYVHVPASHNKYYMLLARTFVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAMGFILGPAFQAALSVIGETGITINGISLQVNMYTAPALMGALLGIGNIILIFAIFRE--------------HRVDDL------EKNVSSINSE--SEV-TDVEKANEGPIDQIA-------------VISSNILFFVVLFVFAIFETISTPLTMDMYAWTRTQAVFYNGIILAAVGVESVIVFLTVKILCKKTGERVLLLGGLAVIWIGFF---ILLPWGNQMPKIQWTDLQNATI 372
[Close]
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NHS3|MFSD8_HUMAN (Major facilitator superfamily domain-containing protein 8 OS=Homo sapiens OX=9606 GN=MFSD8 PE=1 SV=1)

HSP 1 Score: 52.7582 bits (125), Expect = 6.513e-6
Identity = 81/378 (21.43%), Postives = 168/378 (44.44%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRT-KALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPA-----ATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPD--VDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFG 1558
            FL+ V  ++++ ++W Y + K    A +S+    +A+++L   + +P++G   +  +R  K  L++S  + V  N +Y     P     + +++ R + GIG+G+   + +     T+ +ERT+ +  + + + +G I+GP        L    + + +  + +N+Y +P  L A L  +  I +L    +  VD SG       Q K+IN       +E            E   D  +  +  ID                 +++  + F + F     E ++ P+T+  + W +    ++N  +  A G   ++I+  ++ +S+ + +R++LL GLI + + +    I+L   N   KI +  L +  I    FG
Sbjct:   47 FLSSVGFSVVMMSIWPY-LQKIDPTADTSFLGWVIASYSLGQMVASPIFGL--WSNYRPRKEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSAFLGILNIILILAILREHRVDDSG------RQCKSIN-------FE------------EASTDEAQVPQGNIDQVA-------------VVAINVLFFVTLFIFALFETIITPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGVKLLSKKIGERAILLGGLIVVWVGFF---ILLPWGNQFPKIQWEDLHNNSIPNTTFG 380
[Close]
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8HRG6 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 4.677e-113
Identity = 195/443 (44.02%), Postives = 275/443 (62.08%), Query Frame = 2 
Query:  440 KFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGF-RTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKK------------------SIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPY 1711
            K  + +  +TWG LTGVERAIILPTLWLYF  KF   AA  +Y ATLAAFN+S  +  PL+G+L+ + + R K LL+ +NQLE+ GN++YFVA +PW++ +GRF+AG+G+G+E PLYADVVRVT  +ERT  IV LLLARQ GLI GPA TL++HP+++++    +++YNSPG  MA+LW V TI ++  YP +        S   G N +E+          +DTS   +     D+     + +  A+                   S+ K   Y   +T ++L + FSSYF L++LEAVLPP   RYF W+E + S VYL AG LVI +Y +++ +S   +DR +LLTG+  L+ +Y W  + L  +  ++  LYI+L+  GI  H+ G+    A  ESL+TKS+P  EMD+AQ V R+ I  S+LVGP I GSLQ  P+
Sbjct:   35 KLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTIS------HSRFAGGNGDEVAAES------TDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAKFEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQFVPW 465
[Close]
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267FNL8 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g2 PE=4 SV=1)

HSP 1 Score: 357.451 bits (916), Expect = 1.098e-112
Identity = 195/443 (44.02%), Postives = 275/443 (62.08%), Query Frame = 2 
Query:  440 KFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGF-RTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKK------------------SIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPY 1711
            K  + +  +TWG LTGVERAIILPTLWLYF  KF   AA  +Y ATLAAFN+S  +  PL+G+L+ + + R K LL+ +NQLE+ GN++YFVA +PW++ +GRF+AG+G+G+E PLYADVVRVT  +ERT  IV LLLARQ GLI GPA TL++HP+++++    +++YNSPG  MA+LW V TI ++  YP +        S   G N +E+          +DTS   +     D+     + +  A+                   S+ K   Y   +T ++L + FSSYF L++LEAVLPP   RYF W+E + S VYL AG LVI +Y +++ +S   +DR +LLTG+  L+ +Y W  + L  +  ++  LYI+L+  GI  H+ G+    A  ESL+TKS+P  EMD+AQ V R+ I  S+LVGP I GSLQ  P+
Sbjct:   41 KLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTIS------HSRFAGGNGDEVAAES------TDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAKFEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQFVPW 471
[Close]
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267GD89 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g1 PE=4 SV=1)

HSP 1 Score: 355.14 bits (910), Expect = 9.114e-112
Identity = 194/442 (43.89%), Postives = 274/442 (61.99%), Query Frame = 2 
Query:  440 KFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGF-RTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKK-----------------SIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPY 1711
            K  + +  +TWG LTGVERAIILPTLWLYF  KF   AA  +Y ATLAAFN+S  +  PL+G+L+ + + R K LL+ +NQLE+ GN++YFVA +PW++ +GRF+AG+G+G+E PLYADVVRVT  +ERT  IV LLLARQ GLI GPA TL++HP+++++    +++YNSPG  MA+LW V TI ++  YP +        S   G N +E+          +DTS   +     D+     + +  A+                  S+ K   Y   +T ++L + FSSYF L++LEAVLPP   RYF W+E + S VYL AG LVI +Y +++ +S   +DR +LLTG+  L+ +Y W  + L  +  ++  LYI+L+  GI  H+ G+    A  ESL+TKS+P  EMD+AQ V R+ I  S+LVGP I G LQ  P+
Sbjct:   41 KLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTIS------HSRFAGGNGDEVAAES------TDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAKFEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGLLQFVPW 470
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BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A0X3PDP8 (Putative MFS-type transporter C330.07c OS=Schistocephalus solidus OX=70667 GN=YJ87 PE=4 SV=1)

HSP 1 Score: 348.591 bits (893), Expect = 2.013e-109
Identity = 180/428 (42.06%), Postives = 272/428 (63.55%), Query Frame = 2 
Query:  425 NKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFP 1708
            +K  PK+ I+   +TWGFLT VERAIILPT+WLYF   +G + A S+Y +TLAAF+LS+ +  PL+G+  +     + LL+ +N +EV+GN+ Y +   PW V  GR IAG+G+  E P+YAD+ R T   ERT YI+ILLL+RQVGLIIGPA TLIL  I  +IG V +++YN PG +MA+LW V T+ +  +YP +DKSG L++    G+  +  +     E ++  +    ++ I                     F+ Y  Y+ ++L  ++FS+YF ++SLE+VL PV  R+F WNEV  SYVY+ +  LVII+ G++  ++R ++DR+++L GL FL +SY +++ +L  + +  K L  +L+  G+  H+ G+   +A  ESL+TK +P  ++D AQT+LRT IN + L+GPY+ GSLQ  P
Sbjct:   67 HKRPPKYAIAFIASTWGFLTNVERAIILPTMWLYFRDYWGDEVAKSFYGSTLAAFSLSILVTTPLFGYAGHANVNVRHLLMFANFMEVIGNVAYLLPYSPWFVFFGRLIAGVGASCESPMYADLTRTTEESERTPYIIILLLSRQVGLIIGPAFTLILRQITIEIGPVQISVYNGPGLVMAVLWVVHTMLIFFTYPHLDKSGELVEELQSGEVASSPV-----EASLKHSRQPSDSRIQV------------------SFAGYGQYHIVTLYFVIFSAYFCVMSLESVLSPVANRFFKWNEVEVSYVYIGSSVLVIIVSGLMHLMTRCMEDRALVLLGLFFLTVSYAFLSFVLHNVLTMTKTLGATLVVVGVAIHVIGMPFPLAITESLYTKFIPSHQLDKAQTILRTIINVAFLLGPYVGGSLQGKP 471
[Close]
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A183LD87 (MFS domain-containing protein OS=Schistosoma margrebowiei OX=48269 PE=4 SV=1)

HSP 1 Score: 347.821 bits (891), Expect = 5.659e-109
Identity = 180/424 (42.45%), Postives = 272/424 (64.15%), Query Frame = 2 
Query:  440 KFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHR-DSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFP 1708
            KF +    +TWGFL+ VERA+ILPTLWLY    +G+  A+++Y  T+AAF+LS+ +  P+YG  +Y G R K LL+I+N LE++GN+IY  A  P  V++GR I+GIG+  E PLYAD+VR TN +ERT YI++LLL RQ+GLI GP+ TL++  + +++ + +LN+YN PG LMAILW + +  +L SYP+VDK+G ++ ++ Q    +     +  E+   D+   L+      +S +   T I+N+ +       Y  +N ++L  + F++YF+ +SLEA LPPV  R F W EV  SYVYLAA  L+I +  +L+ +++   DR +LL GL+ ++ISY W+T+ + L+      + I L   GI  H+ G+    A +ESL+TK  P  +MD AQ++ RT IN + LVGPY+ GSL  +P
Sbjct:   79 KFWMVFTASTWGFLSNVERAVILPTLWLYLKEYWGADVANTHYGTTVAAFSLSILIMTPIYGLASYSGVRVKTLLMIANLLEIIGNLIYLFAPVPSAVILGRLISGIGASCEPPLYADIVRATNRDERTTYIIVLLLTRQIGLIFGPSFTLMMAKMNYRVANFALNVYNGPGLLMAILWLLHSFVILFSYPNVDKNGRVIYNNGQRSCCDRENWIQPNEQPKEDSRPRLSDSTDSLNSGRFSTTVINNSLR------HYLSFNIIALYCVNFAAYFSFMSLEAALPPVANRIFQWTEVETSYVYLAASILIIFVVILLRILNQFYTDRVLLLAGLVTMVISYFWLTVTVYLLPEVPVRMGIPLTLAGIAIHVLGIPFTYAYSESLYTKLAPVSDMDRAQSIFRTVINVAFLVGPYVGGSLIGYP 496
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BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000001851.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:23268477:23283346:-1 gene:ENSAMXG00000001817.2 transcript:ENSAMXT00000001851.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 147.517 bits (371), Expect = 3.895e-38
Identity = 116/413 (28.09%), Postives = 195/413 (47.22%), Query Frame = 2 
Query:  497 AIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNIN-------------EMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            ++ILPT+W Y  T     A   +    L+AF+ S  L  PL+G ++ K   TK +++ +N  E+VGN +YF+    W+++  R +AGIG+G+   +++ + R T  E+R+     ++  RQ GL+IGPA  + L    FQ+G   +N + +PG  M  LW +  + VL+ Y D  +  +  + S + K                  ++H         T S     I   ++ +      +  +  H  S++     + LL   F + F   +LE ++ P+T ++F++ E+ NS +Y   G  VI  +  ++ +SR V +R VL  GLI   IS VW  I L     +     I     G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:    6 SVILPTIWRYLQTL---DAPPYFLGLGLSAFSFSGLLSGPLFGLISDKTRTTKKIILFANCFEIVGNFMYFMGYSKWLLLSSRLVAGIGTGAGSSIFSFLTRNTVPEDRSTVFAAVMACRQAGLLIGPAFNIFLRLCDFQLGPFIVNKFTAPGIFMCGLWLLLQLVVLLMYWDFPEPAS--RGSREDKQQQEDGEDEEDENDEVRPLVHPHELTGSYGTVSIPPPRIPTVANGNLPRRSPSPPEQSH--SKFLREEVVVLLTAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFVFVRWLSRRVAERVVLAIGLILCNISCVWCLIFLANPQGALAEFII-----GVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGVRRSIGGLATILGPLWAGGL 406
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BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 101.293 bits (251), Expect = 1.645e-22
Identity = 58/160 (36.25%), Postives = 91/160 (56.88%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPG 955
            FL+GVE A+ILPT+W Y        A + +    L+AF+ S  L  PL+G  +     TK++++ SN  E+VGN +YF+    W+++  R +AGIG+G+   ++  + R T  +ER      ++  RQ GL+IGPA  + L    F++G   +N Y SPG
Sbjct:   19 FLSGVEYAVILPTIWKYLQIL---DAPAYFLGLGLSAFSFSGLLSGPLFGRWSDVTRTTKSIILFSNVFEIVGNFMYFLGYSKWLLLASRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPG 175

HSP 2 Score: 71.2478 bits (173), Expect = 9.302e-13
Identity = 50/167 (29.94%), Postives = 82/167 (49.10%), Query Frame = 2 
Query: 1202 FSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMS--CGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            FS +     + LL   F + F   +LE ++ P+T +YF + E+ NS +Y   G  VI  + +++ +SR ++DR+VL  GL+    + VW  I L    S +    + L     G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:  229 FSEFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIGGFFLVRWLSRVLEDRAVLAVGLLICCGACVWCIIFLA---SPQGGFAVELTEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 392
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:103022629])

HSP 1 Score: 50.8322 bits (120), Expect = 3.080e-6
Identity = 84/369 (22.76%), Postives = 157/369 (42.55%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNI----IYFVAS-EPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPI-----KFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGI 1540
            FL+ V   I++ ++W Y + K    A +S+    +AA++L   + +PL+G  +    R + L V S    V  NI    +Y + S   + +++ R   G G+G+   + + V   T+ +ERT+ +  +   + +G I+GPA    L  I           + LN+Y +P  L A+                            G     ++I  + E  + D   H+ T I+  S + +       +++I + +       L+   + F   F     E +  P+++  F W      ++N  +  A GF  II++ +++ +S  + DR VLL+GL  + I +    I+L   N   KI +  L +  I
Sbjct:   40 FLSSVGFTIVITSIWPY-LQKIDDTADASFLGWVVAAYSLGQMVASPLFGLWSNHRPRREPL-VCSIFFNVSANIYYAYVYLIPSYNKYHMLLARAFVGFGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAALSFIGEKGYTLHFLELKLNMYTAPALLAAVF---------------------------GVINILLVIIILREHRVDDYGRHI-TAINYVS-EDEVEVPPEVEENIDQIA------VLTSNVLFFVILFIFAVFETISTPLSMDMFAWTRKEAVLYNGIILAAIGFESIIVFLVVKVISVRIGDRPVLLSGLAIVFIGFF---ILLPWGNQYPKIQWADLQNNSI 368
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BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO49760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFQ2])

HSP 1 Score: 164.466 bits (415), Expect = 3.175e-44
Identity = 122/433 (28.18%), Postives = 208/433 (48.04%), Query Frame = 2 
Query:  482 TGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDV------DKSGAL---------LKSSSQG----------KNINEMIIHKIYEKNMSDTSSHLNTE---IHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
             G+E A+ILPT+WLY   +F  QA S +Y    AAF+ S  + +PL+G        TKA ++ +N  E+ GN +YF+A   + ++ GR +AGIG+G    ++A + R T  EERT+   I +  RQ GL+IGP   + L    F++G   ++ Y SPG  MA +W +Q I ++  Y D+      DK             L ++ +G           NI    I+   + N+ + SS  N++   +H+    S  + I +  +   +  R      + +LA  F  +F   + EA+  P++     W E+ NS  Y       I+ + ++  VS+ + DR +++ G+IF  ++ VW  I+L      E  +  +++  G    +FGL        SL +K    +   + Q   R++   ++++GP   GSL
Sbjct:   22 AGMEYAVILPTMWLYASERF--QAESWFYGIIFAAFSFSSLIMSPLFGMWVDYTRNTKACILFANLFEMGGNFLYFIAWSKYWILGGRLVAGIGAGVSSAIFAQIARTTTEEERTSVYSIAMGLRQFGLLIGPGMNVFLKECNFKLGPFKVDHYTSPGLFMAAIWLLQEILMIFMYYDLPSVNQNDKEPVFTEKPQITNGLHANKEGITNGGLSHLPDNIGS--INTAAKDNLCEISSLNNSDSATVHKRRSSSVSSHIVDTWRLSKELMR---EEIIIILASQFIMFFNETAFEALFTPLSNHLLGWKELENSVAYCLIALEAILTFVLVSKVSKRLSDRWLMVIGVIFEGLALVWYLIMLADSKPYEAKILPTVI-VGTLIIVFGLPFFSVANISLLSKLTDDKVQGVVQGFQRSSTGVAMILGPMWGGSL 446
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008970.2 (major facilitator superfamily domain-containing protein 8 [Source:NCBI gene;Acc:101156398])

HSP 1 Score: 171.014 bits (432), Expect = 4.375e-46
Identity = 126/446 (28.25%), Postives = 208/446 (46.64%), Query Frame = 2 
Query:  479 LTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYE--------------------------------------KNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILG--LINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            L+GVE A+ILPT+W Y  T     A   +   TL+AF+LS  L  PL+G L+ +   TK +++ +N  E++GN++YF+    W+++  R +AGIG+G+   ++  + R T +E+R      ++  RQ GL+IGPA  + L    F +GS  +N Y +PG  M +LW +  + V+  Y D+           + +   + +IHK  E                                      +  S  SS  N+ I           + + K S   +  +     + LLA  F + F   +LE ++ P+T +YF++ E+ NS +Y   G +VI  +  ++ +S+HV +R VL  GL    IS +W  I L   L   S ++    +   G+F  + GL  V     SLF+K    +    +Q V R+    + ++GP  AG L
Sbjct:   20 LSGVEYAVILPTIWRYLQTL---NAEPYFLGLTLSAFSLSGLLSGPLFGHLSDRTQTTKKIILFANFFEIIGNLMYFMGYSKWLLLSSRLVAGIGTGAGSSIFGFLTRSTASEDRATVFAAVMACRQAGLLIGPAFNIFLRLCNFHLGSFVVNKYTAPGLFMCLLWILLQLVVVFMYWDLPY--------LERRKTKDSVIHKEEENTHASVEDEEEGDEEVKPLMTSQELVGSYGSVVAPDPCRKHSRVSSIHNSPISSPVTSQSHEHVTSLKSS-SLYREFLREEVVVLLAAQFITLFNQTALETMVTPLTQKYFNFGELENSVMYCLGGVVVIAGFLFVRWLSKHVAERVVLAIGLTICNISCIWCLIFLAKPLGGFSWQLTEFII---GVFLQVLGLPFVAVAQVSLFSKITSEKTQGFSQGVRRSVGGLATILGPLWAGGL 450
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: si:ch211-38m6.6 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:105356178])

HSP 1 Score: 166.392 bits (420), Expect = 2.073e-44
Identity = 123/446 (27.58%), Postives = 208/446 (46.64%), Query Frame = 2 
Query:  479 LTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNI----------------NEMIIHKIYEKNMS---DTSSHLNTEIHR-------DSDKSKRTFIDNAKKSIHK------FSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILY-ISLMSCGIFFHIFGLSLVIACAESLFT-------KSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSL 1696
            L+G+E A+ILPT+W Y       +A   +    L+AF+LS  L  PL+GF + +   TK++++ SN  E+ GN +YF+    W+++  R +AGIG+G+   ++  + R T  EER      ++  RQ GL+IGPA  L L    F++G  ++N Y SPG  M +LW +    VL  Y DV      +KS  +G  +                +E + H     N+     TS  +   I          +D  ++ F+   K  + +       + +     + +L   F + F   +LE ++ P+T RYF + E+ NS +Y   G  VI+ +  ++ +S  V DR+VL  GL+    + VW  +   L N      + ++    G+F  + GL  V   A    +       K++  + +  +Q V R+    + ++GP  AG L
Sbjct:   29 LSGIEYAVILPTIWRYLQIL---EAPPYFLGLGLSAFSLSGLLTGPLFGFWSDRSKTTKSIILFSNLFEIAGNFMYFLGYSKWLLLCSRLVAGIGAGAGSSIFGFLTRSTLPEERAGIFAAVMACRQAGLLIGPAFNLFLRLCDFKLGPFAVNKYTSPGIFMCLLWLLLQFVVLALYWDVPP----IKSEEEGLRMEMKQEDEEEEAPLIRGDEQLAHTYRAVNLDHCYQTSLFIKKSIFLMHFHCFFKTDVLQKDFVTPVKVRVKRSLGLSVCAEFLREEVVVVLTAQFITLFNQTALETMVTPMTQRYFSFGELGNSLMYSLCGVEVILGFFFVRWLSGKVADRAVLAGGLVICCFACVWCLVF--LCNPRGGYGWELTAFIIGVFLQLLGLPFVAVSATDCCSVCMMVTKKNVKTDRLWFSQGVRRSVGGLATILGPLWAGGL 465
[Close]
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:101161364])

HSP 1 Score: 52.7582 bits (125), Expect = 7.806e-7
Identity = 82/364 (22.53%), Postives = 155/364 (42.58%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEP-----WMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLIL-----HPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNE----VHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISL 1525
            FL+ V   I++ +LW Y + K  S A +S+    +AA++L   + +PL+G+ +    R + L V S  + +  NI Y  A  P     + ++M R   G G+G+   + + V   T+  ERT  +  +   + +G I+GPA    L       I   +  + L++Y +P  L A+   +  + V++          +LK             H++ E      + +  +E         R  I+  + SI + +       L    + F+  F     E +  P+++  F W      ++N  +  A GF  I+++  +++ S+   DR VLL G   +   ++   ++L   N   KI +  L
Sbjct:   42 FLSSVGFTIVITSLWPY-LEKVDSGADASFLGWMVAAYSLGQMVASPLFGWWSNHRPRREPL-VCSIFINLAANIYYAYAYLPKTNNKYHLLMSRAFVGFGAGNVAVVRSYVAGATSLRERTGAMANMSACQALGFILGPALQAGLTFIGEEGITVDVIKLQLSMYTTPALLAALFGLINILLVVL----------VLKE------------HRVDEDGKQIQAINYTSE--------DRVNIEEDELSIDQVA------VLISNILFFTVMFIFAVFETIATPLSMDMFSWTRKEAVLYNGIIMCAIGFESILVFLAVKAASQRFGDRPVLLAGFAVIFCGFI---VLLPWGNHYPKIQWADL 364
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BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000066500.1 (SMESG000066500.1)

HSP 1 Score: 888.256 bits (2294), Expect = 0.000e+0
Identity = 485/487 (99.59%), Postives = 485/487 (99.59%), Query Frame = 2 
Query:  329 MNDSNYKSFNAIXXXXXXXXXXXXYFKCENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPYXXXXXXXXXXXXXXXXXXXRYHLFDI 1789
            MNDSNYKSFNAIEDDESDANSSSEYFKCENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQAASSYYAATLAAFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTN EERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEI RDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPYLVFIILFLFMSFSLQFLVLRYHLFDI
Sbjct:    1 MNDSNYKSFNAIEDDESDANSSSEYFKCENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQAASSYYAATLAAFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNPEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIRRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPYLVFIILFLFMSFSLQFLVLRYHLFDI 487
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BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000075932.1 (SMESG000075932.1)

HSP 1 Score: 481.1 bits (1237), Expect = 4.455e-165
Identity = 246/429 (57.34%), Postives = 325/429 (75.76%), Query Frame = 2 
Query:  428 KIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDS-DKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPY 1711
            K+  K  I    A+ GFL GVER+IILP+LWLYF+TKFG++AA  YY  TL+AFNLSVF+ AP YG+LA KGFRTK LL+ISNQLE++GNIIYF+ASEPWM++ GRF+ GIG+GSEVPLYADVVRVTN +ERT+YI+ILLL+RQ+GLIIGPA TLILHP+KFQ+G+++LNIYNSPGF+M ILW +QTI +LI YP++ K G+ + ++     + + I  K+++   S T +      + DS + +  TF    K+  +K  +Y +  T++LL I F SYF LISLE+++PP+TVRYF W+EVHNSY+YL AG LVI+   +LQ VS +V D+   + GL+ L+ SY+ ++  L  I S+++ L ISLM  GI  HIFGLS+VIAC ESL+TK+LP  EMD+ Q+VLRT INFSLLVGPY+AGSLQ + +
Sbjct:   40 KLSSKLCIIGSAASVGFLNGVERSIILPSLWLYFITKFGNEAAERYYGGTLSAFNLSVFVIAPFYGYLAQKGFRTKFLLIISNQLEIIGNIIYFIASEPWMILFGRFVCGIGAGSEVPLYADVVRVTNVKERTSYIIILLLSRQIGLIIGPAVTLILHPVKFQVGNITLNIYNSPGFIMGILWAIQTIVILIIYPEISKDGSEIDNTRINMRLEQRIFKKVFDGESSKTVT------NEDSVEYNSITFNGKVKEIFNKSKQYTNLVTVTLLCITFVSYFCLISLESIIPPITVRYFKWSEVHNSYLYLLAGILVIVTLLLLQKVSNYVTDQKSYVCGLLLLICSYLILSFTLLFIESNQQNLSISLMGIGILLHIFGLSIVIACGESLYTKTLPISEMDLGQSVLRTVINFSLLVGPYVAGSLQFYSF 462
[Close]
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000022267.1 (SMESG000022267.1)

HSP 1 Score: 339.732 bits (870), Expect = 4.712e-111
Identity = 200/403 (49.63%), Postives = 266/403 (66.00%), Query Frame = 2 
Query:  410 CENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIH------KIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSV-SRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFT 1597
            C N + K   KF I    A WGFLTG+ERA+I+PTLWLYF   F    AS YY  TLAAFN+++ L  PL+G+LA+ G R K LLVISNQL ++GNIIYF+AS PWMV++GRF+AG G+G EVPLYAD+VRVT+ +ERT YIV LLL RQ GLIIGPA TL++  IK +IG VS++IYN PG L+A+LW   TI VL+ YP +      L  S +   +  M +       K Y  ++ D  + L   I      +    I N    I+ +  Y  Y+ LS L I+FSSYF+L+ LE+VLPP+  RYF W E+  S+VYL  G  VI++Y IL+ + SR V+DR++LL+GLI L ISY+W++I L +I+  +  L+ISL+  GI FH+ G    I+C+ESL+T
Sbjct:    5 CWNYVGK--SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIID--AQLKQGIEELPSPTTMERISNFFNPIN-YKDYLKYSILSNLFIIFSSYFSLMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGLILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYT 402
[Close]
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000039774.1 (SMESG000039774.1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.158e-13
Identity = 78/356 (21.91%), Postives = 149/356 (41.85%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVA-------SEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKF----QIGSVSLNIYNSPG---------FLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVH----NSYVYLAAGFLVIIIYGILQSVSRHVKDRSVLLTGLIFLLISYVWM 1471
            F T V  +I +P+LW Y +       +  +    +A +++      PL+ +++ K    K +L++S  +   GN +Y V        ++   ++  R + GI   +  P+   +   T  EER   + IL   + +G IIGP       PI +    +I    +N+Y + G          L+ +++C QT     +    ++   + +S S G N    II K+                        +TFI++            +++ + +L   F    +L  LE    P+T+  F W+  H    NS +  ++G   I I+  L+ V + +K++ V +TG + +L S ++M
Sbjct:   49 FFTSVSYSIQMPSLWPY-MNIIDDTYSKEFLGWVVAVYSIGQLFTCPLFSYISGKTGCFKTILILSAIIAGTGNYLYSVIVDIDGKLAKKISLLTSRIVIGIAGANIAPIRLFLTLATTEEERIGPMSILSACQGLGFIIGPGLQAAFVPIGYPGIIEIPFFRINMYTASGIFGVLSNFVILILLIFCFQT-----TVTKKNEEFTIQRSESMGSNQKYEIIRKV-----------------------DKTFIND------------YFSAIFMLLAFFICMMSLAVLETSTTPMTMDNFGWSRSHATLINSIILASSGICSIGIFISLKYVVKIIKEKIVFITGFVLILCSAIYM 363
[Close]
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000078496.1 (SMESG000078496.1)

HSP 1 Score: 52.7582 bits (125), Expect = 7.936e-7
Identity = 52/219 (23.74%), Postives = 98/219 (44.75%), Query Frame = 2 
Query:  476 FLTGVERAIILPTLWLYFVTKFGSQXXXXXXXXXXXXFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIY-----FVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSV-----SLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMIIHKIYEKN 1102
            FL+ V  +I LP++W Y +    ++         +A F++       ++G    +    +  L+ S      GN+ Y     F       +++ RFI G GSG+       V   +  EE+TA + ++   + +G I GP       P+ +  G+V     +LN++ + GF+ AI   V  + +LI +   D+S     +++   N+   I+ K+ EK+
Sbjct:   36 FLSSVGFSITLPSIWPY-LKVLDAKVTKKSLGIVVAIFSIGQLFGGIIFGLAINQLESFRKPLIASITFMFFGNLFYSYLANFKQYGKSFLILSRFIVGFGSGNVAITRTFVTAFSKPEEKTAQVALMSAFQGLGFIFGPCIQTSFIPLGYP-GAVNEQYFALNMFTAAGFMGAITSIVNIVLLLIYF--YDRSPYAKYANTDEINVEAAILKKLLEKS 250
The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MFSD87.802e-721.43major facilitator superfamily domain containing 8 ... [more]
MFSD81.356e-621.43major facilitator superfamily domain containing 8 ... [more]
MFSD81.356e-621.43major facilitator superfamily domain containing 8 ... [more]
MFSD81.356e-621.43major facilitator superfamily domain containing 8 ... [more]
MFSD81.356e-621.43major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Y53G8AR.73.677e-824.24pep chromosome:WBcel235:III:3282308:3290215:1 gene... [more]
ZK550.24.268e-825.35pep chromosome:WBcel235:IV:17245584:17249750:1 gen... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-38m6.62.101e-4127.19si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
CABZ01045212.12.621e-4027.09major facilitator superfamily domain-containing pr... [more]
CABZ01045212.13.743e-4028.04major facilitator superfamily domain-containing pr... [more]
si:ch211-38m6.69.375e-2125.25si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
si:ch211-38m6.61.398e-1130.77si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc183.163e-4727.51DnaJ heat shock protein family (Hsp40) member C18 ... [more]
dnajc183.510e-4727.51DnaJ heat shock protein family (Hsp40) member C18 ... [more]
dnajc186.763e-4527.06DnaJ heat shock protein family (Hsp40) member C18 ... [more]
MFSD82.764e-722.16major facilitator superfamily domain containing 8 ... [more]
MFSD83.122e-622.16major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 2
Match NameE-valueIdentityDescription
sp|Q6GPQ3|MFSD8_XENLA3.252e-621.95Major facilitator superfamily domain-containing pr... [more]
sp|Q8NHS3|MFSD8_HUMAN6.513e-621.43Major facilitator superfamily domain-containing pr... [more]
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BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HRG64.677e-11344.02MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A267FNL81.098e-11244.02MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A267GD899.114e-11243.89MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A0X3PDP82.013e-10942.06Putative MFS-type transporter C330.07c OS=Schistoc... [more]
A0A183LD875.659e-10942.45MFS domain-containing protein OS=Schistosoma margr... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSAMXT00000001851.23.895e-3828.09pep primary_assembly:Astyanax_mexicanus-2.0:5:2326... [more]
si:ch211-38m6.61.645e-2236.25si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
mfsd83.080e-622.76major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO497603.175e-4428.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000008970.24.375e-4628.25major facilitator superfamily domain-containing pr... [more]
si:ch211-38m6.62.073e-4427.58major facilitator superfamily domain-containing pr... [more]
mfsd87.806e-722.53major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000066500.10.000e+099.59SMESG000066500.1[more]
SMESG000075932.14.455e-16557.34SMESG000075932.1[more]
SMESG000022267.14.712e-11149.63SMESG000022267.1[more]
SMESG000039774.15.158e-1321.91SMESG000039774.1[more]
SMESG000078496.17.936e-723.74SMESG000078496.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025634 ID=SMED30025634|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1861bp
AATTCAATCCAATTTTGTAATGTTTGCTCTAATAAAATTTATGATACCAT
CTTAACTTTGTTACAGTTAATATATTCAGCATAAATTGAGTCTATGTCGA
CATTGATAGTTATAATTACTAAAATAACATTTATTTAAATCAACAAAGAA
AATCTCTTCAATCCAATTCCGTCGTTTTTTATAAATAAATAGATAATATC
AATAACACACCTGAATTGAGCACATATGTAGGTTGTTCAAAAATTGATTT
ATTTTGAACACCGCCAGTACATTATTCAGTATTTTAGAAAAAAAGTTTTC
TGTTTTTCAACAACAGATAAATTTTCTTATGAACGATTCAAATTATAAAT
CATTCAATGCAATCGAAGATGATGAAAGTGATGCTAACAGTTCTTCTGAA
TATTTTAAATGTGAAAATAAACTCAACAAAATTCAACCAAAGTTCACAAT
CTCTGTTTGTTGTGCAACATGGGGTTTCTTAACTGGTGTAGAAAGAGCAA
TCATTTTGCCTACACTATGGCTCTACTTCGTTACTAAATTCGGAAGTCAA
GCAGCTTCTTCTTATTATGCGGCCACGCTTGCAGCATTCAATTTATCAGT
ATTTCTATTTGCACCACTTTACGGATTTCTTGCATATAAAGGTTTTAGAA
CGAAAGCGTTACTAGTTATCAGCAATCAGCTTGAAGTTGTCGGGAATATT
ATCTATTTTGTTGCTTCAGAACCTTGGATGGTTATGATGGGTCGATTTAT
TGCAGGAATCGGATCTGGAAGTGAAGTTCCTTTATATGCAGATGTTGTTC
GTGTTACAAATGCTGAAGAGAGAACGGCGTATATTGTGATTTTACTTCTT
GCTCGTCAAGTTGGTTTAATCATTGGACCGGCTGCAACTTTAATTTTGCA
TCCAATAAAATTTCAAATTGGATCTGTATCTCTCAATATATACAACAGTC
CGGGATTTTTAATGGCAATTTTATGGTGTGTTCAAACTATTCAAGTACTT
ATAAGTTACCCAGATGTTGATAAATCAGGTGCACTTTTAAAGAGTTCTTC
TCAAGGGAAAAATATTAATGAAATGATAATTCATAAAATATATGAAAAAA
ACATGTCAGATACATCTAGTCACTTGAATACAGAAATTCATAGAGACTCA
GATAAATCAAAACGTACATTTATTGACAACGCAAAAAAATCAATTCACAA
ATTCTCTAGATATGCTCATTATAATACTTTATCTCTACTTGCTATTGTAT
TTAGCTCATATTTTGCCCTAATCAGTTTAGAGGCGGTGTTACCACCAGTT
ACTGTTAGATATTTTCACTGGAATGAAGTACATAACAGTTATGTTTATTT
AGCCGCAGGATTCCTTGTTATTATTATATATGGAATCTTGCAATCAGTTT
CTCGACATGTAAAAGATAGAAGCGTACTTTTGACAGGACTCATATTTTTA
TTAATTTCTTATGTATGGATGACTATAATTCTTGGTCTTATAAACTCATC
AGAAAAAATTCTTTATATTTCGTTAATGTCTTGTGGAATTTTTTTCCATA
TTTTTGGCTTATCTTTAGTTATTGCATGTGCAGAATCCTTGTTTACAAAA
TCATTGCCTCCCGAAGAAATGGATATGGCACAAACTGTTCTAAGGACAAC
AATAAATTTTTCACTTTTAGTTGGACCTTATATTGCTGGTTCACTACAGA
TTTTTCCATATTTGGTATTTATTATTTTATTTTTATTCATGTCCTTTTCA
TTACAATTCTTGGTGCTAAGATATCATTTGTTTGATATATAAATAATATT
AACTTTTTTGGAAATCGGATGTAGTGTACATAGGGTTCATGATTTTAAAT
TGATTCTTGTG
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protein sequence of SMED30025634-orf-1

>SMED30025634-orf-1 ID=SMED30025634-orf-1|Name=SMED30025634-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=488bp
MNDSNYKSFNAIEDDESDANSSSEYFKCENKLNKIQPKFTISVCCATWGF
LTGVERAIILPTLWLYFVTKFGSQAASSYYAATLAAFNLSVFLFAPLYGF
LAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEV
PLYADVVRVTNAEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSV
SLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMI
IHKIYEKNMSDTSSHLNTEIHRDSDKSKRTFIDNAKKSIHKFSRYAHYNT
LSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIII
YGILQSVSRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLM
SCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGP
YIAGSLQIFPYLVFIILFLFMSFSLQFLVLRYHLFDI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000034epidermis
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR036259MFS_trans_sf
IPR011701MFS
IPR020846MFS_dom
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR011701Major facilitator superfamilyPFAMPF07690MFS_1coord: 49..450
e-value: 6.2E-29
score: 101.0
NoneNo IPR availablePANTHERPTHR23510FAMILY NOT NAMEDcoord: 40..483
NoneNo IPR availablePANTHERPTHR23510:SF16coord: 40..483
NoneNo IPR availableCDDcd17326MFS_MFSD8coord: 50..485
e-value: 9.71588E-30
score: 117.695
NoneNo IPR availableTMHMMTMhelixcoord: 295..317
NoneNo IPR availableTMHMMTMhelixcoord: 80..102
NoneNo IPR availableTMHMMTMhelixcoord: 337..354
NoneNo IPR availableTMHMMTMhelixcoord: 394..416
NoneNo IPR availableTMHMMTMhelixcoord: 366..388
NoneNo IPR availableTMHMMTMhelixcoord: 167..189
NoneNo IPR availableTMHMMTMhelixcoord: 437..459
NoneNo IPR availableTMHMMTMhelixcoord: 43..65
NoneNo IPR availableTMHMMTMhelixcoord: 204..226
NoneNo IPR availableTMHMMTMhelixcoord: 463..485
IPR020846Major facilitator superfamily domainPROSITEPS50850MFScoord: 41..487
score: 13.547
IPR036259MFS transporter superfamilySUPERFAMILYSSF103473MFS general substrate transportercoord: 43..478