Protein kinase domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025633 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 1
Homology
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 463.381 bits (1191), Expect = 9.361e-156 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 141 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 493
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 463.381 bits (1191), Expect = 9.361e-156 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 141 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 493
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 462.611 bits (1189), Expect = 1.558e-155 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 143 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 495
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 462.611 bits (1189), Expect = 1.558e-155 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 143 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 495
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Match: CLK2 (CDC like kinase 2 [Source:HGNC Symbol;Acc:HGNC:2069]) HSP 1 Score: 462.225 bits (1188), Expect = 2.322e-155 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 142 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 494
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 413.305 bits (1061), Expect = 2.017e-135 Identity = 205/352 (58.24%), Postives = 257/352 (73.01%), Query Frame = 1
Query: 1045 EDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLD-LKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRF 2097
+DD+ GHL+Y GD + NR+ I +TLGEGTFGKVV D L + +A+KIIKN+ KYREAA LE+ VL+ L EKDP+ K I M +F+YNGHIC+ F L+G S+F+FLK N Y PYPMEQ HI +Q+C AV FLH+N LTHTDLKPENILFV+S Y KK V+ S+ +RLIDFGSATFDHE HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI++EL++G TLFQTH+NREHLAMM+R+LG IP +M + T +F I+G+L W DA +VR+NCK L+R + S P + VELF+L+ ML ++P AR+KL +AL H +F RLP N +
Sbjct: 238 QDDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVRVNDSLSDTF--MALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTT-KLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTKTKFF-INGRLDWVNTSADAAYVRDNCKP--LRRSM--SCTDPEH---VELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLKI 578
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 409.838 bits (1052), Expect = 3.992e-134 Identity = 205/354 (57.91%), Postives = 257/354 (72.60%), Query Frame = 1
Query: 1045 EDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLD-LKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTP--KDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRF 2097
+DD+ GHL+Y GD + NR+ I +TLGEGTFGKVV D L + +A+KIIKN+ KYREAA LE+ VL+ L EKDP+ K I M +F+YNGHIC+ F L+G S+F+FLK N Y PYPMEQ HI +Q+C AV FLH+N LTHTDLKPENILFV+S Y KK V+ S+ +RLIDFGSATFDHE HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI++EL++G TLFQTH+NREHLAMM+R+LG IP +M + T + F I+G+L W DA +VR+NCK L+R + S P + VELF+L+ ML ++P AR+KL +AL H +F RLP N +
Sbjct: 238 QDDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVRVNDSLSDTF--MALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTT-KLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTNTFRTKFFINGRLDWVNTSADAAYVRDNCKP--LRRSM--SCTDPEH---VELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLKI 581
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 416.001 bits (1068), Expect = 5.382e-133 Identity = 206/352 (58.52%), Postives = 257/352 (73.01%), Query Frame = 1
Query: 1045 EDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLD-LKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRF 2097
+DD+ GHL+Y GD + NR+ I +TLGEGTFGKVV D L + +A+KIIKN+ KYREAA LE+ VL+ L EKDP+ K I M +F+YNGHIC+ F L+G S+F+FLK N Y PYPMEQ HI +Q+C AV FLH+N LTHTDLKPENILFV+S Y KK V+ S+ +RLIDFGSATFDHE HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI++EL++G TLFQTH+NREHLAMM+R+LG IP +M + T K F I+G+L W DA +VR+NCK L+R + S P + VELF+L+ ML ++P AR+KL +AL H +F RLP N +
Sbjct: 532 QDDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVRVNDSLSDTF--MALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTT-KLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRT-KTKFFINGRLDWVNTSADAAYVRDNCKP--LRRSM--SCTDPEH---VELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLKI 872
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 412.535 bits (1059), Expect = 1.464e-131 Identity = 205/354 (57.91%), Postives = 257/354 (72.60%), Query Frame = 1
Query: 1045 EDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLD-LKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTP--KDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRF 2097
+DD+ GHL+Y GD + NR+ I +TLGEGTFGKVV D L + +A+KIIKN+ KYREAA LE+ VL+ L EKDP+ K I M +F+YNGHIC+ F L+G S+F+FLK N Y PYPMEQ HI +Q+C AV FLH+N LTHTDLKPENILFV+S Y KK V+ S+ +RLIDFGSATFDHE HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI++EL++G TLFQTH+NREHLAMM+R+LG IP +M + T + F I+G+L W DA +VR+NCK L+R + S P + VELF+L+ ML ++P AR+KL +AL H +F RLP N +
Sbjct: 532 QDDKDGHLIYSKGDFILNRFTIYDTLGEGTFGKVVRVNDSLSDTF--MALKIIKNVSKYREAAKLEVKVLQKLAEKDPEKKNWVIHMGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTT-KLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTNTFRTKFFINGRLDWVNTSADAAYVRDNCKP--LRRSM--SCTDPEH---VELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLKI 875
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Match: madd-3 (Probable dual specificity protein kinase madd-3 [Source:UniProtKB/Swiss-Prot;Acc:G5EDB2]) HSP 1 Score: 321.627 bits (823), Expect = 1.519e-104 Identity = 158/265 (59.62%), Postives = 197/265 (74.34%), Query Frame = 1
Query: 1300 MYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
M +F+YNGHIC+ F L+G S+F+FLK N Y PYPMEQ HI +Q+C AV FLH+N LTHTDLKPENILFV+S Y KK V+ S+ +RLIDFGSATFDHE HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI++EL++G TLFQTH+NREHLAMM+R+LG IP +M + T +F I+G+L W DA +VR+NCK L+R + S P + VELF+L+ ML ++P AR+KL +AL H +F RLP N +
Sbjct: 1 MGSYFDYNGHICLLFDLMGSSIFDFLKANHYKPYPMEQTLHITWQLCNAVKFLHDNKLTHTDLKPENILFVDSRYTT-KLVDKKPLRVLHSTHVRLIDFGSATFDHEHHSIIVSTRHYRAPEVILELGWSQPCDVWSIGCILYELYTGVTLFQTHENREHLAMMERVLGDIPLRMAKRTKTKFF-INGRLDWVNTSADAAYVRDNCKP--LRRSM--SCTDPEH---VELFELIENMLMFEPLARMKLPEALQHRYFNRLPENLK 256
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299748) HSP 1 Score: 458.759 bits (1179), Expect = 3.412e-154 Identity = 219/362 (60.50%), Postives = 279/362 (77.07%), Query Frame = 1
Query: 1015 SPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
S K V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R T YF GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 135 SQAKTAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYF-YHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 486
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299752) HSP 1 Score: 458.759 bits (1179), Expect = 3.412e-154 Identity = 219/362 (60.50%), Postives = 279/362 (77.07%), Query Frame = 1
Query: 1015 SPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
S K V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R T YF GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 135 SQAKTAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYF-YHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 486
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299745) HSP 1 Score: 459.144 bits (1180), Expect = 2.963e-153 Identity = 219/362 (60.50%), Postives = 279/362 (77.07%), Query Frame = 1
Query: 1015 SPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
S K V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R T YF GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 204 SQAKTAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYF-YHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 555
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299742) HSP 1 Score: 459.144 bits (1180), Expect = 2.963e-153 Identity = 219/362 (60.50%), Postives = 279/362 (77.07%), Query Frame = 1
Query: 1015 SPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
S K V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R T YF GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 204 SQAKTAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYF-YHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 555
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Match: Doa (gene:FBgn0265998 transcript:FBtr0299750) HSP 1 Score: 459.144 bits (1180), Expect = 2.963e-153 Identity = 219/362 (60.50%), Postives = 279/362 (77.07%), Query Frame = 1
Query: 1015 SPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
S K V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R T YF GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 204 SQAKTAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARKTKTKYF-YHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 555
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2b (CDC-like kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060929-1126]) HSP 1 Score: 448.358 bits (1152), Expect = 3.301e-150 Identity = 208/358 (58.10%), Postives = 271/358 (75.70%), Query Frame = 1
Query: 1039 VVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNK 2109
V+DDE GHL+Y+ GD L +RYEI TLGEGTFGKVVEC+D +R ++A+KIIKN+EKY+EAA LEINVL+ + ++DP+ K LC++M DWF+Y+GH+C+SF+LLGLS F+F+KEN Y+PY + QVRH+AYQ+C AV FLH+N LTHTDLKPENILFV+SDY+V+ ++ KK+ V S+ +R++DFGSATFDHE HS++VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TL+QTHDNREHLAMM+RI G +P +M R T K + G+L W+ ++VRENC+ L+ Y +E + FDLL +LEY+P+ R+ LS AL H FF L + F +
Sbjct: 144 AVKDDEEGHLIYRAGDVLQDRYEITQTLGEGTFGKVVECVDHQRGGSRIALKIIKNVEKYKEAARLEINVLEKINQRDPENKNLCVQMLDWFDYHGHMCLSFELLGLSTFDFMKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVSSDYSVLYNAEKKRDERSVNSTAVRIVDFGSATFDHEHHSSIVSTRHYRAPEVILELGWSQPCDVWSIGCILFEFYCGYTLYQTHDNREHLAMMERIHGPVPSRMIRKTRKQKYFYRGRLDWDESTSAGRYVRENCRP-------LRRYMLCESEDHHQFFDLLEGLLEYEPEQRLSLSAALRHPFFSLLRDTEHFSGGR 494
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 447.588 bits (1150), Expect = 2.119e-149 Identity = 211/346 (60.98%), Postives = 265/346 (76.59%), Query Frame = 1
Query: 1036 IVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ V DDE GHL+ + GD L RYEI +TLGEGTFG+V++C+D +R VA+KIIKN+EKY+EAA LEINVL+ + EKDP+ LC++M+DWF+Y+GH+CISF+LL LS F+FLKEN Y+PY + QVRH+AYQ+C AV FLHEN LTHTDLKPENILFVNSDY V + KK+ VK++ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIG I+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L+ AL H FF
Sbjct: 166 LCVRDDEEGHLICRSGDVLQERYEIVSTLGEGTFGRVMQCIDHRRGGAHVALKIIKNVEKYKEAARLEINVLERINEKDPENNNLCVQMFDWFDYHGHMCISFELLALSTFDFLKENNYLPYSINQVRHMAYQVCLAVKFLHENKLTHTDLKPENILFVNSDYTVTYNVEKKRDERTVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGSILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPL---RRYLLSEAEEHH----QLFDLIEAMLEYEPSKRLTLAAALRHPFF 504
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 447.588 bits (1150), Expect = 2.141e-149 Identity = 211/346 (60.98%), Postives = 265/346 (76.59%), Query Frame = 1
Query: 1036 IVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ V DDE GHL+ + GD L RYEI +TLGEGTFG+V++C+D +R VA+KIIKN+EKY+EAA LEINVL+ + EKDP+ LC++M+DWF+Y+GH+CISF+LL LS F+FLKEN Y+PY + QVRH+AYQ+C AV FLHEN LTHTDLKPENILFVNSDY V + KK+ VK++ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIG I+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L+ AL H FF
Sbjct: 165 LCVRDDEEGHLICRSGDVLQERYEIVSTLGEGTFGRVMQCIDHRRGGAHVALKIIKNVEKYKEAARLEINVLERINEKDPENNNLCVQMFDWFDYHGHMCISFELLALSTFDFLKENNYLPYSINQVRHMAYQVCLAVKFLHENKLTHTDLKPENILFVNSDYTVTYNVEKKRDERTVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGSILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKPL---RRYLLSEAEEHH----QLFDLIEAMLEYEPSKRLTLAAALRHPFF 503
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk4a (CDC-like kinase 4a [Source:ZFIN;Acc:ZDB-GENE-030131-576]) HSP 1 Score: 401.749 bits (1031), Expect = 5.020e-132 Identity = 188/344 (54.65%), Postives = 255/344 (74.13%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
VEDDE GHL+Y GD L RYEI TLGEG FGKVVEC+D ++ ++A+KIIKNIE+YR+AA+ E+ VL+ + D D +Y C++MYDWF+++GHICI+F+LLGLS ++FLKEN + P+ + +RH+AYQ+ AV FLH+N LTHTDLKPENILFVNS+YN+ +SK K+ VK+ +++++DFG+AT++HE H++VVSTRHYRAPEVIL+LGWS CDVWS+GCI+ E + GSTLFQTHD++EHLAMM+R+LG IP M + T K F + KL W+ ++VR+ C K L+ Y ++ +LFDL+ RMLEYD R+ L +A+ H FF
Sbjct: 152 VEDDEEGHLVYHSGDMLRARYEIVCTLGEGAFGKVVECIDHEKVGARIALKIIKNIERYRDAALSEVEVLEQINSLDCDRRYACVRMYDWFDHHGHICIAFELLGLSTYDFLKENNFQPFYINHIRHMAYQIIRAVRFLHKNKLTHTDLKPENILFVNSEYNIRYNSKMKRDERTVKNPDVKVVDFGNATYEHEHHTSVVSTRHYRAPEVILDLGWSHSCDVWSVGCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPTHMLQKTRKSRFVRNDKLDWDIHSSSGRYVRKQC-------KPLRQYLVSSSSDHEQLFDLIERMLEYDVTKRITLDEAIKHPFF 488
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Match: clk4b (CDC-like kinase 4b [Source:ZFIN;Acc:ZDB-GENE-050227-19]) HSP 1 Score: 390.578 bits (1002), Expect = 4.769e-128 Identity = 186/355 (52.39%), Postives = 258/355 (72.68%), Query Frame = 1
Query: 1009 STSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
S S +K+ +EDDE GHL+Y GD L RYEI TLGEG FGKVVECLD + +VA+KIIKNIE+YREAA+ E++VL+ + D + ++ C++M DWF+++GHICI F+LLGLS ++FLKEN ++P+ + Q+RH+A Q+ AV FLH+N LTHTDLKPENILFV+S+Y++ +S+ K+ +K +++++DFG+AT+DHE H++VVSTRHYRAPEVILELGW+Q CDVWS+GCI+ E + G TLFQTHD++EHLAMM+++LG IP + + T K + KL W+ ++VR++CK L K S P +E+ LFDLL +M+EYD R+ L A+ H FF
Sbjct: 124 SRSHRRKRTKSIEDDEEGHLVYHNGDMLRARYEIVGTLGEGAFGKVVECLDHTKGNVRVALKIIKNIERYREAALSEVDVLERINSLDDEKRFACVRMLDWFDHHGHICIVFELLGLSTYDFLKENGFMPFSLTQIRHMADQIFRAVRFLHKNKLTHTDLKPENILFVDSNYDIKYNSRMKRDERTLKRLDVKVVDFGNATYDHEHHTSVVSTRHYRAPEVILELGWNQACDVWSLGCILVEFYLGLTLFQTHDSKEHLAMMEKVLGPIPTHLLQKTKKRRYVHHDKLDWDEHSSAGRYVRKHCKPL----KQYMSSKTPEHEL---LFDLLQKMMEYDSSKRITLEQAIGHPFF 471
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ezr (ezrin [Source:Xenbase;Acc:XB-GENE-484766]) HSP 1 Score: 429.483 bits (1103), Expect = 8.929e-143 Identity = 199/351 (56.70%), Postives = 262/351 (74.64%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQ 2091
VE+D+ GHL+ + G+ + RYEI LG+GTFGKVVECLDL R +VA+KII+N+ KYREAA LEINVL+ ++E+D D K +C+ M DWF+++GH+CI+F+LLG S F F KEN ++PYP+ +RH+A+Q+C A+ FLHEN LTHTDLKPENILFVNS+Y++ + SKK + VK+ IR++DFGSATFDHE H+T+V+TRHYR PEVILELGWSQPCDVWS+GCI+FE ++G TLFQTHDNREHL MM++ILG +P +M T K + +G LIW+ D ++V +NC +L SY ++ V+LFDLLSRMLE+ P R+ L +AL H FF L Q
Sbjct: 137 VENDKEGHLVCRTGERIQERYEIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYREAAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIRHMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATFDHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILGPLPRRMVYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLM-------SYKSSDSAEHVQLFDLLSRMLEFRPALRITLQEALEHQFFTCLKPQQ 480
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ezr (ezrin [Source:Xenbase;Acc:XB-GENE-484766]) HSP 1 Score: 429.483 bits (1103), Expect = 1.307e-142 Identity = 199/357 (55.74%), Postives = 264/357 (73.95%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNK 2109
VE+D+ GHL+ + G+ + RYEI LG+GTFGKVVECLDL R +VA+KII+N+ KYREAA LEINVL+ ++E+D D K +C+ M DWF+++GH+CI+F+LLG S F F KEN ++PYP+ +RH+A+Q+C A+ FLHEN LTHTDLKPENILFVNS+Y++ + SKK + VK+ IR++DFGSATFDHE H+T+V+TRHYR PEVILELGWSQPCDVWS+GCI+FE ++G TLFQTHDNREHL MM++ILG +P +M T K + +G LIW+ D ++V +NC +L SY ++ V+LFDLLSRMLE+ P R+ L +AL H FF L + N+
Sbjct: 142 VENDKEGHLVCRTGERIQERYEIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYREAAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIRHMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATFDHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILGPLPRRMVYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLM-------SYKSSDSAEHVQLFDLLSRMLEFRPALRITLQEALEHQFFTCLKPEENALGNR 491
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: ezr (ezrin [Source:Xenbase;Acc:XB-GENE-484766]) HSP 1 Score: 402.905 bits (1034), Expect = 9.674e-135 Identity = 188/323 (58.20%), Postives = 245/323 (75.85%), Query Frame = 1
Query: 1105 EINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
EI LG+GTFGKVVECLDL R +VA+KII+N+ KYREAA LEINVL+ ++E+D D K +C+ M DWF+++GH+CI+F+LLG S F F KEN ++PYP+ +RH+A+Q+C A+ FLHEN LTHTDLKPENILFVNS+Y++ + SKK + VK+ IR++DFGSATFDHE H+T+V+TRHYR PEVILELGWSQPCDVWS+GCI+FE ++G TLFQTHDNREHL MM++ILG +P +M T K + +G LIW+ D ++V +NC +L SY ++ V+LFDLLSRMLE+ P R+ L +AL H FF
Sbjct: 9 EIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYREAAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIRHMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATFDHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILGPLPRRMVYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLM-------SYKSSDSAEHVQLFDLLSRMLEFRPALRITLQEALEHQFF 324
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dkk3 (dickkopf WNT signaling pathway inhibitor 3 [Source:Xenbase;Acc:XB-GENE-877183]) HSP 1 Score: 405.216 bits (1040), Expect = 1.935e-133 Identity = 196/362 (54.14%), Postives = 266/362 (73.48%), Query Frame = 1
Query: 991 SDSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPK-DYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
S T S KK++ VE DE GHL+ + GD L RYEI + LGEG FGKV+EC+D R ++VAVKIIKN+E+YREAA EI VL+ L KDP + C++M +WF+++GHICI F+LLGLS ++F+KEN ++P+P++ +R++AYQ+C ++NFLH+N LTHTDLKPENILFV+SDY V + +KK+ +K+S+I+++DFGSAT++ E HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI+ E + G T+FQTHD++EHLAMM+RILG +P M + T K YF +D +L W+ ++V++ CK L+ Y +N+ +LFDL+ RMLEYDP R+ L +AL H FF
Sbjct: 123 SSRTSHLKSHRKKRSRSVEVDEEGHLICESGDVLRERYEIVHALGEGAFGKVLECIDHLRGGERVAVKIIKNVERYREAAQSEIQVLEHLNRKDPINTFRCVQMLEWFDHHGHICIVFELLGLSTYDFIKENSFLPFPLDHIRNMAYQICKSINFLHQNQLTHTDLKPENILFVHSDYVVHFNHAKKQDERYLKNSDIKIVDFGSATYNDEYHSALVSTRHYRAPEVILELGWSQPCDVWSIGCILIEYYLGLTVFQTHDSKEHLAMMERILGPLPLHMIKKTRKHKYFYLD-RLDWDEHSSAGRYVKKRCKP-------LKEYMVSDNKDHHQLFDLIQRMLEYDPAKRITLEEALKHPFF 476
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Match: dkk3 (dickkopf WNT signaling pathway inhibitor 3 [Source:Xenbase;Acc:XB-GENE-877183]) HSP 1 Score: 401.364 bits (1030), Expect = 2.073e-133 Identity = 195/357 (54.62%), Postives = 265/357 (74.23%), Query Frame = 1
Query: 1006 FSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPK-DYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
F S KK++ VE DE GHL+ + GD L RYEI + LGEG FGKV+EC+D R ++VAVKIIKN+E+YREAA EI VL+ L KDP + C++M +WF+++GHICI F+LLGLS ++F+KEN ++P+P++ +R++AYQ+C ++NFLH+N LTHTDLKPENILFV+SDY V + +KK+ +K+S+I+++DFGSAT++ E HS +VSTRHYRAPEVILELGWSQPCDVWSIGCI+ E + G T+FQTHD++EHLAMM+RILG +P M + T K YF +D +L W+ ++V++ CK L+ Y +N+ +LFDL+ RMLEYDP R+ L +AL H FF
Sbjct: 25 FQKSHRKKRSRSVEVDEEGHLICESGDVLRERYEIVHALGEGAFGKVLECIDHLRGGERVAVKIIKNVERYREAAQSEIQVLEHLNRKDPINTFRCVQMLEWFDHHGHICIVFELLGLSTYDFIKENSFLPFPLDHIRNMAYQICKSINFLHQNQLTHTDLKPENILFVHSDYVVHFNHAKKQDERYLKNSDIKIVDFGSATYNDEYHSALVSTRHYRAPEVILELGWSQPCDVWSIGCILIEYYLGLTVFQTHDSKEHLAMMERILGPLPLHMIKKTRKHKYFYLD-RLDWDEHSSAGRYVKKRCKP-------LKEYMVSDNKDHHQLFDLIQRMLEYDPAKRITLEEALKHPFF 373
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 459.144 bits (1180), Expect = 3.250e-154 Identity = 220/365 (60.27%), Postives = 278/365 (76.16%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNKHLISK 2124
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF L P N + + IS+
Sbjct: 143 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEDHH----QLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR 500
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 458.373 bits (1178), Expect = 5.221e-154 Identity = 220/365 (60.27%), Postives = 278/365 (76.16%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNKHLISK 2124
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF L P N + + IS+
Sbjct: 142 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEDHH----QLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk2 (CDC-like kinase 2 [Source:MGI Symbol;Acc:MGI:1098669]) HSP 1 Score: 458.373 bits (1178), Expect = 5.273e-154 Identity = 220/365 (60.27%), Postives = 278/365 (76.16%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNKHLISK 2124
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF L P N + + IS+
Sbjct: 141 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEDHH----QLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR 498
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk3 (CDC-like kinase 3 [Source:MGI Symbol;Acc:MGI:1098670]) HSP 1 Score: 436.032 bits (1120), Expect = 2.491e-143 Identity = 207/358 (57.82%), Postives = 265/358 (74.02%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL-PSNQRFQSNK 2109
VEDD+ GHL+ +IGD L RYEI LGEGTFGKVVECLD R +VA+KII+N+ KYREAA LEINVLK ++EKD + K+LC+ M DWFN++GH+CI+F+LLG + F FLKEN + PYP+ VRH+AYQ+C A+ FLHEN LTHTDLKPENILFVNS++ + + K + VK++ IR+ DFGSATFDHE H+T+V+TRHYR PEVILELGW+QPCDVWSIGCI+FE + G TLFQTH+NREHL MM++ILG IP M T K + G L+W+ D ++V+ENC K L+SY ++ V+LFDL+ RMLE+DP R+ L++AL H FF L P + F S++
Sbjct: 284 VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENC-------KPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSR 634
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Match: Clk3 (CDC-like kinase 3 [Source:MGI Symbol;Acc:MGI:1098670]) HSP 1 Score: 395.201 bits (1014), Expect = 1.115e-129 Identity = 183/296 (61.82%), Postives = 229/296 (77.36%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRL 1926
VEDD+ GHL+ +IGD L RYEI LGEGTFGKVVECLD R +VA+KII+N+ KYREAA LEINVLK ++EKD + K+LC+ M DWFN++GH+CI+F+LLG + F FLKEN + PYP+ VRH+AYQ+C A+ FLHEN LTHTDLKPENILFVNS++ + + K + VK++ IR+ DFGSATFDHE H+T+V+TRHYR PEVILELGW+QPCDVWSIGCI+FE + G TLFQTH+NREHL MM++ILG IP M T K + G L+W+ D ++V+ENCK L
Sbjct: 150 VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPL 445
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P49760|CLK2_HUMAN (Dual specificity protein kinase CLK2 OS=Homo sapiens OX=9606 GN=CLK2 PE=1 SV=1) HSP 1 Score: 462.611 bits (1189), Expect = 7.484e-155 Identity = 221/360 (61.39%), Postives = 279/360 (77.50%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNK 2109
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG IP +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF RL P N+ + S++
Sbjct: 143 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGARVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPIPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEEHH----QLFDLIESMLEYEPAKRLTLGEALQHPFFARLRAEPPNKLWDSSR 495
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|O35491|CLK2_MOUSE (Dual specificity protein kinase CLK2 OS=Mus musculus OX=10090 GN=Clk2 PE=1 SV=2) HSP 1 Score: 458.373 bits (1178), Expect = 3.652e-153 Identity = 220/365 (60.27%), Postives = 278/365 (76.16%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISS-SKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL---PSNQRFQSNKHLISK 2124
VEDD GHL+Y +GD L RYEI +TLGEGTFG+VV+C+D +R +VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K LC++M+DWF+Y+GH+CISF+LLGLS F+FLK+N Y+PYP+ QVRH+A+Q+C AV FLH+N LTHTDLKPENILFVNSDY + + KK+ VKS+ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L +AL H FF L P N + + IS+
Sbjct: 142 VEDDAEGHLIYHVGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVNSDYELTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYVGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL---RRYLTSEAEDHH----QLFDLIENMLEYEPAKRLTLGEALQHPFFACLRTEPPNTKLWDSSRDISR 499
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|P49762|DOA_DROME (Serine/threonine-protein kinase Doa OS=Drosophila melanogaster OX=7227 GN=Doa PE=1 SV=2) HSP 1 Score: 449.899 bits (1156), Expect = 1.756e-145 Identity = 216/359 (60.17%), Postives = 277/359 (77.16%), Query Frame = 1
Query: 1039 VVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTR-----STPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCK-PNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
V++DD GHL+Y GD LH+RY+I TLGEGTFG+VV+ D++R Y +A+KIIKN+EKYREAA LEIN L+ + +KDP +LC+KM DWF+Y+GH+CI F++LGLSVF+FL+EN Y PYP++QVRH+AYQ+C++V FLH+N LTHTDLKPENILFV+SDY + K ++ VK++++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R S K + GKL W+ ++VR++CK LFL C+ ++E ELF L+ +MLEY+P +R+ L +AL+H FF RLP + R
Sbjct: 458 VIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDY-CMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFL--------CQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 807
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q63117|CLK3_RAT (Dual specificity protein kinase CLK3 OS=Rattus norvegicus OX=10116 GN=Clk3 PE=1 SV=2) HSP 1 Score: 432.95 bits (1112), Expect = 2.418e-143 Identity = 207/358 (57.82%), Postives = 265/358 (74.02%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL-PSNQRFQSNK 2109
VEDD+ GHL+ +IGD L RYEI LGEGTFGKVVECLD R +VA+KII+N+ KYREAA LEINVLK ++EKD + K+LC+ M DWFN++GH+CI+F+LLG + F FLKEN + PYP+ VRH+AYQ+C A+ FLHEN LTHTDLKPENILFVNS++ + + K + VK++ IR+ DFGSATFDHE H+T+V+TRHYR PEVILELGW+QPCDVWSIGCI+FE + G TLFQTH+NREHL MM++ILG IP M T K + G L+W+ D ++V+ENCK L+SY ++ V+LFDL+ RMLE+DP R+ L++AL H FF L P + F S++
Sbjct: 136 VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKP-------LKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHSSR 486
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q3SX21|CLK3_BOVIN (Dual specificity protein kinase CLK3 OS=Bos taurus OX=9913 GN=CLK3 PE=2 SV=1) HSP 1 Score: 431.409 bits (1108), Expect = 7.577e-143 Identity = 206/358 (57.54%), Postives = 264/358 (73.74%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL-PSNQRFQSNK 2109
VEDD+ GHL+ +IGD L RYEI LGEGTFGKVVECLD R +VA+KII+N+ KYREAA LEINVLK ++EKD + K+LC+ M DWFN++GH+CI+F+LLG + F FLKEN + PYP+ VRH+AYQ+C A+ FLHEN LTHTDLKPENILFVNS++ + + K + VK++ IR+ DFGSATFDHE H+T+V+TRHYR PEVILELGW+QPCDVWSIGCI+FE + G TLFQTH+NREHL MM++ILG IP M T K + G L+W+ D ++V+ENCK L+SY + V+LFDL+ RMLE+DP R+ L++AL H FF L P + F +++
Sbjct: 136 VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKP-------LKSYMLQDTLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSR 486
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1B6ELR1 (Protein kinase domain-containing protein OS=Cuerna arida OX=1464854 GN=g.20634 PE=4 SV=1) HSP 1 Score: 473.011 bits (1216), Expect = 4.393e-156 Identity = 226/356 (63.48%), Postives = 278/356 (78.09%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQH-NVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSN 2106
+EDDE GHL+Y GD L +RY+I TLGEGTFGKVV+ DL+ + +A+KIIKN+EKYREAA LEIN L + EKDP+GK+LC+KM DWF+Y+GH+CI+F++LGLSVF+FLK+N Y PY +EQVRHI+YQ+C+AV FLH+N LTHTDLKPENILFV+SDY + +SKKK+ VKSS++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS PCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R + YF GKL W+ ++VRENC K L Y ++E +LFDL+SRMLEYDP R+ L++AL H FF ++ QR S+
Sbjct: 162 IEDDEDGHLIYHHGDILQDRYKIMATLGEGTFGKVVKVKDLQTE-QMIALKIIKNVEKYREAAKLEINALDKIAEKDPEGKHLCVKMLDWFDYHGHMCIAFEMLGLSVFDFLKDNNYQPYTLEQVRHISYQLCYAVKFLHDNKLTHTDLKPENILFVDSDYEMTYNSKKKRDVRRVKSSDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCIIFELYLGITLFQTHDNREHLAMMERILGTIPYRMARKSKTKYF-YHGKLDWDEKSSAGRYVRENC-------KPLHRYQTVDDEDHRQLFDLISRMLEYDPTERITLAEALRHPFFEKIQPVQRLGSS 508
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1B6JMD1 (Protein kinase domain-containing protein OS=Homalodisca liturata OX=320908 GN=g.12024 PE=4 SV=1) HSP 1 Score: 473.011 bits (1216), Expect = 4.489e-156 Identity = 226/356 (63.48%), Postives = 279/356 (78.37%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQH-NVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSN 2106
+EDDE GHL+Y GD L +RY+I TLGEGTFGKVV+ DL+ ++ +A+KIIKN+EKYREAA LEIN L + EKDP+GK+LC+KM DWF+Y+GH+CI+F++LGLSVF+FLK+N Y PY +EQVRHI+YQ+C+AV FLH+N LTHTDLKPENILFV+SDY + +SKKK+ VKSS++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS PCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R + YF GKL W+ ++VRENC K L Y ++E +LFDL+SRMLEYDP R+ L++AL H FF ++ QR S+
Sbjct: 162 IEDDEDGHLIYHHGDILQDRYKIMATLGEGTFGKVVKVKDLQTEH-LIALKIIKNVEKYREAAKLEINALDKIAEKDPEGKHLCVKMLDWFDYHGHMCIAFEMLGLSVFDFLKDNNYQPYTLEQVRHISYQLCYAVKFLHDNKLTHTDLKPENILFVDSDYEMTYNSKKKRDVRRVKSSDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCIIFELYLGITLFQTHDNREHLAMMERILGTIPYRMARKSKTKYF-YHGKLDWDEKSSAGRYVRENC-------KPLHRYQTVDDEDHRQLFDLISRMLEYDPTERITLAEALRHPFFEKIQPVQRLGSS 508
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1B6IP48 (Protein kinase domain-containing protein OS=Homalodisca liturata OX=320908 GN=g.12027 PE=4 SV=1) HSP 1 Score: 477.248 bits (1227), Expect = 1.574e-155 Identity = 226/356 (63.48%), Postives = 279/356 (78.37%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQH-NVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSN 2106
+EDDE GHL+Y GD L +RY+I TLGEGTFGKVV+ DL+ ++ +A+KIIKN+EKYREAA LEIN L + EKDP+GK+LC+KM DWF+Y+GH+CI+F++LGLSVF+FLK+N Y PY +EQVRHI+YQ+C+AV FLH+N LTHTDLKPENILFV+SDY + +SKKK+ VKSS++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS PCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R + YF GKL W+ ++VRENC K L Y ++E +LFDL+SRMLEYDP R+ L++AL H FF ++ QR S+
Sbjct: 318 IEDDEDGHLIYHHGDILQDRYKIMATLGEGTFGKVVKVKDLQTEH-LIALKIIKNVEKYREAAKLEINALDKIAEKDPEGKHLCVKMLDWFDYHGHMCIAFEMLGLSVFDFLKDNNYQPYTLEQVRHISYQLCYAVKFLHDNKLTHTDLKPENILFVDSDYEMTYNSKKKRDVRRVKSSDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCIIFELYLGITLFQTHDNREHLAMMERILGTIPYRMARKSKTKYF-YHGKLDWDEKSSAGRYVRENC-------KPLHRYQTVDDEDHRQLFDLISRMLEYDPTERITLAEALRHPFFEKIQPVQRLGSS 664
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A433T3R6 (Protein kinase domain-containing protein OS=Elysia chlorotica OX=188477 GN=EGW08_016072 PE=4 SV=1) HSP 1 Score: 472.626 bits (1215), Expect = 2.273e-155 Identity = 222/361 (61.50%), Postives = 283/361 (78.39%), Query Frame = 1
Query: 1039 VVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFC---RLPSNQRFQSNK 2109
VEDDE GHL+Y+ GD L RYEI +TLGEGTFGKVVEC DL + +++A+KIIKN+EKYREAA LEINVL+ L+EKD GKYLC++M DWF+Y+GH+CI+F +LGLSVF+FLK+N YVPY +EQVRHI+YQ+C+AVNFLHEN LTHTDLKPENILFVNSD++ + KKK + +K+S+++LIDFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FEL++G TLFQTHDN+EHLAMM+RILG +PY+M + T K + G L W+ ++VR+ C+ L R+ ++ +P +E +LFDL+SR+L Y+P R L A+ H+FF R + QR Q +
Sbjct: 184 AVEDDEDGHLIYRAGDLLQARYEIISTLGEGTFGKVVECKDLHKGNERLALKIIKNVEKYREAAKLEINVLEKLKEKDQSGKYLCVQMRDWFDYHGHMCIAFDMLGLSVFDFLKDNNYVPYTLEQVRHISYQLCYAVNFLHENQLTHTDLKPENILFVNSDFDTYYNPKKKREERRLKNSDLKLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCIMFELYTGYTLFQTHDNKEHLAMMERILGSMPYRMAKKTKKQKYFYRGALDWDDKSSSGRYVRDTCRPL---RRYMK---EPEDEDHQQLFDLISRLLTYEPSQRCTLRQAMRHAFFLPYQREAAGQRGQDGR 538
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Match: A0A1B6G565 (Protein kinase domain-containing protein (Fragment) OS=Cuerna arida OX=1464854 GN=g.20637 PE=4 SV=1) HSP 1 Score: 477.248 bits (1227), Expect = 2.541e-155 Identity = 226/356 (63.48%), Postives = 278/356 (78.09%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQH-NVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSN 2106
+EDDE GHL+Y GD L +RY+I TLGEGTFGKVV+ DL+ + +A+KIIKN+EKYREAA LEIN L + EKDP+GK+LC+KM DWF+Y+GH+CI+F++LGLSVF+FLK+N Y PY +EQVRHI+YQ+C+AV FLH+N LTHTDLKPENILFV+SDY + +SKKK+ VKSS++RLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS PCDVWSIGCI+FEL+ G TLFQTHDNREHLAMM+RILG IPY+M R + YF GKL W+ ++VRENC K L Y ++E +LFDL+SRMLEYDP R+ L++AL H FF ++ QR S+
Sbjct: 335 IEDDEDGHLIYHHGDILQDRYKIMATLGEGTFGKVVKVKDLQTE-QMIALKIIKNVEKYREAAKLEINALDKIAEKDPEGKHLCVKMLDWFDYHGHMCIAFEMLGLSVFDFLKDNNYQPYTLEQVRHISYQLCYAVKFLHDNKLTHTDLKPENILFVDSDYEMTYNSKKKRDVRRVKSSDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCIIFELYLGITLFQTHDNREHLAMMERILGTIPYRMARKSKTKYF-YHGKLDWDEKSSAGRYVRENC-------KPLHRYQTVDDEDHRQLFDLISRMLEYDPTERITLAEALRHPFFEKIQPVQRLGSS 681
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:103024244]) HSP 1 Score: 445.277 bits (1144), Expect = 1.183e-148 Identity = 206/346 (59.54%), Postives = 263/346 (76.01%), Query Frame = 1
Query: 1036 IVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ V DDE GHL+ + GD L RYEI TLGEGTFG+V+EC+D +R VA+KIIKN+EKY+EAA LEINVL+ + E+DP+ K LC++M+DWF+Y+GH+C+SF+LL LS F+FLKEN Y+PY + QVRH+AYQ+C AV FLH+N LTHTDLKPENILFVNSD+ + + KK+ +VK++ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGW+QPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENC K L+ Y E +LFDL+ MLEY+P R+ L+ +L H FF
Sbjct: 161 LCVRDDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMECIDHRRGGSHVALKIIKNVEKYKEAARLEINVLEKINERDPENKNLCVQMFDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVNSDFTITYNVEKKRDERMVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWNQPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENC-------KPLRRYILSEAEEHHQLFDLIEAMLEYEPSKRITLAASLRHPFF 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:103024244]) HSP 1 Score: 445.277 bits (1144), Expect = 1.183e-148 Identity = 206/346 (59.54%), Postives = 263/346 (76.01%), Query Frame = 1
Query: 1036 IVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVI-SSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ V DDE GHL+ + GD L RYEI TLGEGTFG+V+EC+D +R VA+KIIKN+EKY+EAA LEINVL+ + E+DP+ K LC++M+DWF+Y+GH+C+SF+LL LS F+FLKEN Y+PY + QVRH+AYQ+C AV FLH+N LTHTDLKPENILFVNSD+ + + KK+ +VK++ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGW+QPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ ++VRENC K L+ Y E +LFDL+ MLEY+P R+ L+ +L H FF
Sbjct: 161 LCVRDDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMECIDHRRGGSHVALKIIKNVEKYKEAARLEINVLEKINERDPENKNLCVQMFDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSISQVRHMAYQICLAVKFLHDNKLTHTDLKPENILFVNSDFTITYNVEKKRDERMVKNTAVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWNQPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENC-------KPLRRYILSEAEEHHQLFDLIEAMLEYEPSKRITLAASLRHPFF 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk4a (dual specificity protein kinase CLK4-like [Source:NCBI gene;Acc:103029292]) HSP 1 Score: 405.216 bits (1040), Expect = 1.325e-133 Identity = 189/344 (54.94%), Postives = 257/344 (74.71%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
VEDDE GHL+Y GD L RYEI TLGEG FGKVVEC+D + +VA+KIIKNI++YREAAM E+ VL+ + D D +Y C++M DWF+++GH+CI+F+LLGLS F+FLKEN + P+P++Q+RH+AYQ+ AV FLH+N LTHTDLKPENILF++S+Y++ +SK K+ V++++++++DFG+AT++HE H+TVVSTRHYRAPEVILELGWS CDVWSIGCI+ E + GSTLFQTHD++EHLAMM+R+LG IP M + T K + +L W+ ++VR++C K L+ Y K + ELFDL+ +MLEYD R+ L +A+ H FF
Sbjct: 147 VEDDEEGHLIYHSGDILRARYEIVCTLGEGAFGKVVECIDRSNRNARVALKIIKNIDRYREAAMSEVEVLEQMNSLDCDRRYSCVRMLDWFDHHGHVCIAFELLGLSTFDFLKENNFQPFPVDQIRHMAYQIIRAVKFLHKNKLTHTDLKPENILFIDSEYDLEYNSKMKRDERTVRNADVKVVDFGNATYEHEHHTTVVSTRHYRAPEVILELGWSHSCDVWSIGCILIEYYLGSTLFQTHDSKEHLAMMERVLGPIPACMLQKTRKQRYVHHDRLDWDVHSSSGRYVRKHC-------KPLRQYMKSKSLDHEELFDLIEKMLEYDVTKRISLDEAIRHPFF 483
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000007667.2 (dual specificity protein kinase CLK4 [Source:NCBI gene;Acc:103034991]) HSP 1 Score: 402.519 bits (1033), Expect = 1.306e-132 Identity = 191/375 (50.93%), Postives = 263/375 (70.13%), Query Frame = 1
Query: 958 RSSKSASGEIHSDSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSK-KKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRL 2079
RSS+ H + S S +K+ EDDE GHL+Y GD L RYEI T+GEG FGKVVEC+D + +VA+KIIKN+E+YREAA+ E+ VLK + D + ++ C++M DWF+++GHICI F+LLGLS ++FLKEN+++P+ ++Q+R +AYQ+C AV+FLH N LTHTDLKPENILFVNS+Y+ ++K K+ +K+ ++++DFG+AT+DHE H++VVSTRHYRAPEVILELGW+Q CDVWS+GCI+ E + G TLFQTHD++EHLAMM+R+LG IP M + T K + KL W+ ++VR++C K L+ Y +LFDLL +M+EYD R+ L +AL H FF L
Sbjct: 113 RSSRECQNSHHRSNRSHSKSHRRKRTRSFEDDEEGHLIYHNGDMLRARYEIVGTVGEGAFGKVVECIDHSKDGLRVALKIIKNLERYREAALSEVEVLKQMNSLDSENRFACVQMLDWFDHHGHICIVFELLGLSTYDFLKENDFMPFTVDQIRFMAYQLCRAVHFLHRNKLTHTDLKPENILFVNSEYDTEYNAKLKRDEKTLKNLHVKVVDFGNATYDHEYHTSVVSTRHYRAPEVILELGWNQSCDVWSLGCILIEYYLGITLFQTHDSKEHLAMMERVLGPIPVNMLQKTKKQRYVHHEKLDWDEHTSSGRYVRKHC-------KPLKQYMSSKTSDHEQLFDLLHKMMEYDVSKRITLEEALRHPFFTPL 480
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Match: clk2b (CDC-like kinase 2b [Source:ZFIN;Acc:ZDB-GENE-060929-1126]) HSP 1 Score: 385.185 bits (988), Expect = 2.722e-128 Identity = 183/316 (57.91%), Postives = 236/316 (74.68%), Query Frame = 1
Query: 1180 KVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLISK 2124
++A+KIIKN+EKY+EAA LEINVL+ ++EKDP+ K+LC++M+DWF+Y+GH+CISF+LL LS F+F+KEN Y+PY + QVRH+A+Q+C AV FLH+N LTHTDLKPENILFV+SD+ ++ KK++ VK + +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWSQPCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RI G IP +M R T K + G+L W+ ++VRENCK L+ Y E +LFDLL MLEY+P+ R+ LS L H FF L + S +S+
Sbjct: 7 RIALKIIKNVEKYKEAARLEINVLEKIREKDPENKHLCVQMFDWFDYHGHMCISFELLALSTFDFMKENNYLPYSLSQVRHMAFQICIAVKFLHDNKLTHTDLKPENILFVSSDFITNYNTEKKREERSVKDTSVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFEYYLGYTLFQTHDNREHLAMMERIQGPIPSRMIRKTRKQKYFYRGRLDWDENSSAGRYVRENCKP-------LRRYVLSEAEEHHQLFDLLEGMLEYEPERRLLLSSCLRHPFFSCLRDAEHSSSGSRDVSR 315
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: clk2a (CDC-like kinase 2a [Source:ZFIN;Acc:ZDB-GENE-030131-298]) HSP 1 Score: 457.218 bits (1175), Expect = 2.774e-154 Identity = 215/352 (61.08%), Postives = 272/352 (77.27%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQR 2094
VEDDE GHL+Y+IGD L RYEI +TLGEGTFGKVV C+D R K+A+KIIKN++KYREAA LEINVL+ + EKDP KYLC++MYDWF+Y+GH+CI+F+LLGLS F+FLKEN Y+PYP+ QVR +AYQ+C+A+ FLH+N LTHTDLKPENILFV+S+Y++ + KK+ V++++IR++DFGSATFD+E HST+VSTRHYRAPEV+LELGWSQPCDVWSIGCIVFE + G TLFQTHDNREHLAMM+R LG IP +M R T K + G L W+ K+VRENC K L+ Y ++ +LFDL+ +ML+Y+P R+ L +AL H FF L +QR
Sbjct: 149 VEDDEDGHLIYRIGDWLQARYEIISTLGEGTFGKVVHCIDHDRGKAKIALKIIKNVDKYREAARLEINVLEKINEKDPRNKYLCVQMYDWFDYHGHMCIAFELLGLSTFDFLKENNYLPYPLHQVRLMAYQLCYAIKFLHDNKLTHTDLKPENILFVDSEYDIKYNPQKKRDERTVRNADIRVVDFGSATFDYEHHSTIVSTRHYRAPEVLLELGWSQPCDVWSIGCIVFEFYLGFTLFQTHDNREHLAMMERTLGLIPSRMVRRTRKQKYFHHGHLDWDESSSAGKYVRENC-------KPLRRYVVCDDAQHHQLFDLIEKMLQYEPSKRITLGEALKHPFFDLLAQDQR 493
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2804]) HSP 1 Score: 181.415 bits (459), Expect = 2.584e-49 Identity = 109/356 (30.62%), Postives = 188/356 (52.81%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKM------------TRSTPKDYFDI----DGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSF 2067
DDE G ++ D++ RYE+ +G+G+FG+VV+ D K + VA+K+++N +++ A EI +L+ L+++D + I + + F + GH+C++F+LL ++++ +K+N++ + + VR A+ + ++ LH N + H DLKPENIL KQ S I++IDFGS+ F+H++ T + +R YRAPEV+L + P D+WS+GCI+ EL +GS L D + LA +LG P ++ +R P+ Y + DG ++ N A R R + L + + ++ L D L LE++P R+ + AL H +
Sbjct: 144 DDEQGSYVHVAHDHVAYRYEVLKVIGKGSFGQVVKAFDHKTQ-THVALKMVRNEKRFHRQAAEEIRILEHLRKQDRENSMNIIHLLESFTFRGHVCMTFELLSMNLYELIKKNKFQGFSLALVRKFAHSILQCLDTLHRNRIIHCDLKPENILL-------------KQPG---RSGIKVIDFGSSCFEHQRVYTYIQSRFYRAPEVVLGARYGPPIDMWSLGCILAELLTGSPLLPGEDEGDQLACAMELLGMPPQRLLAQGKRSRNFVSSRGHPR-YCGVTEAPDGAVVLN-----AGRSRRGKPRGPPGSRELPAALRGCDDPL--LLDFLRGCLEWEPSERLTPAQALRHPW 474
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: dyrk2 (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2804]) HSP 1 Score: 172.94 bits (437), Expect = 2.489e-46 Identity = 106/358 (29.61%), Postives = 183/358 (51.12%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRST--PKDYFDIDG--------KLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELF-DLLSRMLEYDPKARVKLSDALNHSFFCRLPSN 2088
DDE G ++ D++ RYE+ +G+G+FG+VV+ D R + VA+K+++N +++ A EI +L+ L+++D + I M + FN+ HIC++F+LL ++++ +K+N++ + ++ VR A+ + +N LH+N + H DLKPENIL + I +IDFGS+ ++H++ T + +R YRAP + P D+WS+GCI+ EL +GS L D + LA + G P ++ + + +F G L P+ + R R + + K ++ LF D L + L++DP R+ S AL H + R P N
Sbjct: 154 DDEQGSYIHVPHDHVAYRYEVLRVIGKGSFGQVVKAYD-HRTHQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKENTMNVIHMLESFNFRNHICMTFELLSMNLYELIKKNKFQGFSLQVVRKFAHSILLCLNALHKNRIIHCDLKPENILLRQQGRSGIKI---------------IIDFGSSCYEHQRVYTYIQSRFYRAPGG----RYGLPIDMWSLGCILAELLTGSPLLPGEDEGDQLACAMELTGSPPARLLEQSKRARQFFSSLGHPRYCTVTTLPGGPVVLNGGRTRRGKLRGPPSSRDWTTALKGCDD---HLFIDFLKKCLDWDPATRLTPSQALKHPWLRRRPLN 488
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007958.1 (pep scaffold:Pmarinus_7.0:GL476685:157443:173166:-1 gene:ENSPMAG00000007188.1 transcript:ENSPMAT00000007958.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 160.614 bits (405), Expect = 2.523e-44 Identity = 107/330 (32.42%), Postives = 164/330 (49.70%), Query Frame = 1
Query: 1084 DNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRST--PKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSF 2067
++L RYE+ LG+G+FGKV++CLD K K + VA+K++ EI +LK LQ K I+M + F++ G C+ F+LL ++ + LK + +E VR A + ++ L + + H DLKP NI + + + E++L DFG + FDHE+H T + TRHYRAPEVIL+LG+S P D+WS+GC + EL SG LF H N + L + + G P M + +F I W+ I VR R L + +E D + L++DP+ R+ A++H +
Sbjct: 5 EHLLYRYEVLEVLGQGSFGKVLKCLDHKSK-EFVAIKVLNRARFNESVHRREIEILKRLQTARESSKI--IRMMEHFSFRGRECVVFELLNGNLRSQLKLTHRQGFGLEMVRLFAISLLKSLEQLRDANVIHGDLKPGNIGICSYE----------------AGEVKLFDFGCSCFDHEEHFTKIQTRHYRAPEVILDLGYSFPADMWSLGCTLAELHSGQKLFPGHTNEDQLHSIMEVFGLPPQDMIEESRVQLGFFAITKPTHWD-INNHRGLVRVPGSR------ALPLALRTTDE---HFTDFIRSCLQWDPEWRLTPHGAMDHEW 305
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Match: dyrk1aa (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a [Source:ZFIN;Acc:ZDB-GENE-050302-29]) HSP 1 Score: 169.474 bits (428), Expect = 2.957e-44 Identity = 109/352 (30.97%), Postives = 181/352 (51.42%), Query Frame = 1
Query: 1069 MYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLH--ENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPK--DYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKL------------LQSYCKPNNEVA--VELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ K G+ +RYEI++ +G+G+FG+VV+ D ++ + VA+KIIKN + + A +E+ +L+ + + D D KY + + F + H+C+ F+LL ++++ L+ + + R A QMC A+ FL E + H DLKPENIL N K S I+++DFGS+ ++ + +R YR+PEV+L + + D+WS+GCI+ E+ +G LF + + + + +LG P M PK YF+ W ++K RE + RKL + + + VA ++ DL+ RML+YDPK R+ AL H+FF
Sbjct: 151 IVKNGEKWMDRYEIDSLIGKGSFGQVVKAYD-HQEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTDMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNP----------------KRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGLPPTHMLEQAPKARKYFERLSDGSWT-VKKTKDSKRE--YKTAGSRKLHDIIGVESGGPGGRRMGEAGHTVADYLKFKDLILRMLDYDPKTRITPFYALQHNFF 482
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: KNS1 (Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation [Source:SGD;Acc:S000003942]) HSP 1 Score: 247.284 bits (630), Expect = 8.969e-72 Identity = 145/427 (33.96%), Postives = 222/427 (51.99%), Query Frame = 1
Query: 1051 DESGHLMYKIGDNLHN--RYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDY--------NVISSSKKK------QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRI--------------------LGHIPYKMTRSTPKDYFDIDGKLIWN---------PIEKDAKFVRENCKRL--FLKRKLLQSYCKP---------------------------------NNEVAVELF-------DLLSRMLEYDPKARVKLSDALNHSFF 2070
D+ GH +Y+ D + R+ + + LG+GTFGKV++C+D K + + VAVK+I+ +++YREAA E+ +L+ + DP G++ C+ + + F+Y HIC+ L G S+++F+ N +P ++ IA Q+ +V FLH+ G+ HTDLKPENIL + + V S SK++ + ++K+ EI++IDFGSA F +E H V+STRHYRAPE++L LGWS PCD+WSI C++ EL G +L+ H+N EH+AMM RI LG+ P + + K + L W EK K V ++C RL ++ + L Q Y +E+ E F DLL +M E+DP R+ DAL+H +F
Sbjct: 294 DKDGHYVYQENDIFGSGGRFVVKDLLGQGTFGKVLKCIDNKYEPNYVAVKVIRAVDRYREAAKTELRILQTILNNDPQGQFQCLLLRECFDYKNHICLVTDLYGRSIYDFMCSNGIARFPGSHIQAIARQLIRSVCFLHDLGIIHTDLKPENILICDETHIAQKLPLKTVQSLSKRRREASKGKRKILKNPEIKIIDFGSAIFHYEYHPPVISTRHYRAPEIVLGLGWSFPCDIWSIACVLVELVIGESLYPIHENLEHMAMMQRINGTPFPTDIIDKMFYKSKHKLGNSPSDLNSTVIKHFDRKTLSLQWPEKNKRGDTITTEKSMKRVLQSCDRLDIYISKVLKQDYGDSLSINWNLPPEKNWSLINSKLAWKRQTHSSSSSTTDELDKETFLFWYWFIDLLRKMFEFDPTKRITAKDALDHEWF 720
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: YAK1 (Serine-threonine protein kinase; component of a glucose-sensing system that inhibits growth in response to glucose availability; upon nutrient deprivation Yak1p phosphorylates Pop2p to regulate mRNA deadenylation, the co-repressor Crf1p to inhibit transcription of ribosomal genes, and the stress-responsive transcription factors Hsf1p and Msn2p; nuclear localization negatively regulated by the Ras/PKA signaling pathway in the presence of glucose [Source:SGD;Acc:S000003677]) HSP 1 Score: 155.221 bits (391), Expect = 1.083e-39 Identity = 85/250 (34.00%), Postives = 140/250 (56.00%), Query Frame = 1
Query: 1078 IGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEK-DPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKM 1824
+G + +Y + + LG+GTFG+VV+C +L K + +AVK++K+ +Y ++ E +L+ L +K DP K+ ++MYD F + H+C+ F+LL +++ LK+N++ ++ +R Q+ ++ L E+ L H DLKPENIL D E+++IDFGS+ + T + +R YRAPE+IL + +S D+WS+GCIV ELF G +F L + LG+ P M
Sbjct: 361 LGVEQNRKYLVLDILGQGTFGQVVKCQNLLTK-EILAVKVVKSRTEYLTQSITEAKILELLNQKIDPTNKHHFLRMYDSFVHKNHLCLVFELLSNNLYELLKQNKFHGLSIQLIRTFTTQILDSLCVLKESKLIHCDLKPENILLCAPD----------------KPELKIIDFGSSCEEARTVYTYIQSRFYRAPEIILGIPYSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYPPSWM 593
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 101.293 bits (251), Expect = 3.692e-23 Identity = 90/333 (27.03%), Postives = 144/333 (43.24%), Query Frame = 1
Query: 1090 LHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREA--AMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQ---PCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPI--EKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSF 2067
+ NRY N +G G FG V D KI+K A E+ +LK L+ ++ +C++ + + I +L G + L+ P + V++ YQ+ + ++H G+ H DLKP NIL + ++ ++++ DFG A + + VSTR+YRAPE++L W + D+WS GCI E+ G LF D+ +++ +LG S PKD + N I E KFV L + + + V + DLL +ML +DPK R+ +DAL H +
Sbjct: 19 ITNRYNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRHEN----LICLQDI-FLSPLEDIYFVTELQGTDLHRLLQTR---PLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNIL------------------INENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLT--WQKYDVEVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLG--------SPPKD--------VINTICSENTLKFVTS------LPHRDPIPFSERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPY 301
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 92.8189 bits (229), Expect = 3.938e-21 Identity = 83/331 (25.08%), Postives = 151/331 (45.62%), Query Frame = 1
Query: 1120 LGEGTFGKVVECLDLKRKYDKVAVKIIK--NIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYP----MEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSA---TFDHEKHSTVVSTRHYRAPEVIL-ELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKF---VRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFC 2073
LG GT+ V + L+ K VA+K +K + E A+ EI+++K L+ ++ +++YD + + + F+ + + ++ P + V++ +Q+ + F HEN + H DLKP+N+L + K +++L DFG A S+ V T YRAP+V++ +S D+WS GCI+ E+ +G LF ++ E L ++ I+G TP + +W + K K+ +++ R R++LQ + K + L D L +L+ +P R+ AL+H +F
Sbjct: 13 LGNGTYATVYKGLN-KTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHEN------IVRLYDVIHTENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLL------------------INKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGKPLFPGTNDEEQLKLIFDIMG---------TPNES-------LWPSVTKLPKYNPNIQQRPPRDL--RQVLQPHTK--EPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFA 298
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Match: FUS3 (Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its; inhibits recruitment of Ste5p, Cdc42p-mediated asymmetry and mating morphogenesis [Source:SGD;Acc:S000000112]) HSP 1 Score: 92.0485 bits (227), Expect = 1.361e-20 Identity = 95/340 (27.94%), Postives = 151/340 (44.41%), Query Frame = 1
Query: 1075 KIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEK--YREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSA-----TFDHEKHSTVVSTRHYRAPEVILELG-WSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+I N+ + +++ + LGEG +G V K + VA+K I+ +K + + EI +LK + ++ + I+ D F + I +L+ + + + +++ YQ AV LH + + H DLKP N+L +NS+ ++ V R+ID +A T + V+TR YRAPEV+L +S+ DVWS GCI+ ELF +F D R L ++ I+G TP D D + I +P RE K L + P V + DLL RML +DP R+ +AL H +
Sbjct: 4 RIVYNISSDFQLKSLLGEGAYGVVCSATH-KPTGEIVAIKKIEPFDKPLFALRTLREIKILKHFKHENIITIF-NIQRPDSFENFNEVYIIQELMQTDLHRVISTQMLSD---DHIQYFIYQTLRAVKVLHGSNVIHRDLKPSNLL-INSNCDL---------KVCDFGLARIIDESAADNSEPTGQQSGMTEYVATRWYRAPEVMLTSAKYSRAMDVWSCGCILAELFLRRPIFPGRDYRHQLLLIFGIIG---------TPHS--DNDLRCIESP------RAREYIKSLPMYPAAPLEKMFP--RVNPKGIDLLQRMLVFDPAKRITAKEALEHPYL 309
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO33758 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SR83]) HSP 1 Score: 419.468 bits (1077), Expect = 5.668e-140 Identity = 205/342 (59.94%), Postives = 255/342 (74.56%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQ-HNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
DDE GHL+Y GD LH+RYE++ LGEGTFGKV+EC D K+ D VAVK+IKNIEKYREAA LEI VL+ + +K+ GK LCIKM DWFN++GH+C+ F+ +GLSVF+F+K+N Y PYP++QVRHI+YQ+ AV FLHE LTHTDLKPEN+LFVNSD +V + KQ VKSS +RLIDFGSATF+HE HST VSTRHYRAPEVILELGWS PCD+WSIGCI+FEL++G TLFQTH+NREHLAMM+RI+G IP + + K + GKL W+ K+VRENCK L+ Y ++E F+LL +LEYDP+ R+ +A+ H FF
Sbjct: 107 DDEDGHLIYHKGDQLHSRYEVHCLLGEGTFGKVLECYD-KKTGDVVAVKVIKNIEKYREAAKLEIKVLEKINQKNRYGKSLCIKMLDWFNHHGHMCLVFEKMGLSVFDFMKDNNYEPYPLDQVRHISYQLIVAVKFLHEMKLTHTDLKPENMLFVNSDCDVFYNKDTKQDQRYVKSSHMRLIDFGSATFEHEHHSTTVSTRHYRAPEVILELGWSYPCDIWSIGCIMFELYTGFTLFQTHENREHLAMMERIIGPIPSDFAKKSRKTKYFYKGKLEWDEKSSSGKYVRENCKP-------LKKYMLSDSEGHQLFFNLLDYLLEYDPEKRITAKEAMQHPFF 440
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO46144 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQP1]) HSP 1 Score: 197.593 bits (501), Expect = 7.050e-55 Identity = 119/371 (32.08%), Postives = 198/371 (53.37%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKM--TRSTPKDYFDIDGKLIWNPIEK--DAKFVRENCKRLFLKRKLLQSYCKPNNEVAVE---------LFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLIS 2121
DDE G ++ D++ RYE+ +G+G+FG+VV+ LD K VA+K+++N +++ A EI +L+ L+++D D + I M + F + H+C++F+LL ++++ +K+N++ + + VR A+ + ++ LH+N + H DLKPENIL KQ S I++IDFGS+ ++H++ T + +R YRAPEVIL + P D+WS GCI+ EL +G LF D + LA +LG+IP K+ T K++ + G + I D + + ++ PN++ V+ D L R LE+DP AR+ S AL H + R + +SN +L S
Sbjct: 149 DDEQGSYIHVPKDHIAYRYEVLKIIGKGSFGQVVKALDHKTN-THVALKMVRNEKRFHRQAQEEIRILEHLKKQDKDNTHNIIHMLEHFTFRNHVCMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILL-------------KQQG---RSGIKVIDFGSSCYEHQRIYTYIQSRFYRAPEVILGARYGMPIDMWSFGCILAELLTGYPLFPGEDEGDQLACNMELLGYIPEKLRETSKRAKNFINSKGYPRYCTITTLPDGSVAVSGG-----RSRRGKTRGAPNSKTFVQALKGCDDAMFIDFLKRCLEWDPSARMTPSQALRHPWLRRRALPRAPESNNNLAS 497
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO36294 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ45]) HSP 1 Score: 182.956 bits (463), Expect = 1.077e-51 Identity = 99/293 (33.79%), Postives = 167/293 (57.00%), Query Frame = 1
Query: 994 DSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLI 1872
D+ + P QN +DD +G + + D+L RYE+ LG+G+FG+VV+ LD K VAVKII+N +++ + A++E+ +L L++KD D + I M + F + H+CI+F+L+G++++ +K+N + + + +R A+ + + +H+ + H DLKPENIL +Q + I++IDFGS+ ++H++ T + +R YR+PEVIL L +S D+WS GCI+ EL++G LF + E LA + +LG K+ S + D K I
Sbjct: 25 DAKKIDGVPGAPQNNNYDDD-NGSYLKALHDHLAYRYEVLEVLGKGSFGQVVKALDHKTG-QHVAVKIIRNKKRFHQQALVEVKILDNLRKKDKDNTHNLIHMIEHFYFRNHLCITFELMGMNLYELIKKNNFQGFSLALIRRFAFALLHCLKVIHKEKIIHCDLKPENILL-------------RQRG---QTSIKVIDFGSSCYEHQRVYTYIQSRFYRSPEVILGLPYSMAIDMWSFGCILAELYTGYPLFPGENEVEQLACIMEVLGLPSPKLIESASRRRLFFDSKGI 299
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO45187 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTC8]) HSP 1 Score: 174.866 bits (442), Expect = 1.091e-47 Identity = 113/364 (31.04%), Postives = 187/364 (51.37%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFL--HENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPK--DYFD--IDGKLIWNPIEKDAK-FVRENCKRLF----------LKRKL------LQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
DDE+ + K G+ +RYEI + +G+G+FG+V + D + K + +AVKIIKN + + A +E+ +L+ + + DPDGKY +++ F + H+C+ F+LL ++++ L+ + + R A QMC A+ FL E + H DLKPENIL N K S I+++DFGS+ ++ + +R YR+PEV+L + ++ D+WS+GCI+ E+ +G LF + + + + +LG P + + PK +FD DG ++ K ++ ++L R+L LQ Y K DL+ RML+YD K R+ AL+H FF
Sbjct: 61 DDENYDYIVKAGEKWFDRYEIESLIGKGSFGQVCKAYDHQEK-EHIAVKIIKNKKPFLNQAQIEVKLLELMNKNDPDGKYYIVRLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLCSPELSIIHCDLKPENILLCNP----------------KRSAIKIVDFGSSCQIGQRIYQYIQSRFYRSPEVLLGIPYNLAIDMWSLGCILVEMHTGEPLFSGANEFDQMMKIVEVLGMPPKDILDNAPKARKFFDRLPDGSYQCLKVKDGVKEYLSPGSRKLHDILGCETGGPGGRRLGEAGHTLQDYLK--------FKDLILRMLDYDRKTRIVPYAALHHCFF 399
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Match: EDO47304 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMP9]) HSP 1 Score: 165.622 bits (418), Expect = 5.831e-44 Identity = 111/363 (30.58%), Postives = 170/363 (46.83%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKE-NEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHST-VVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRS--TPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELF-----------------DLLSRMLEYDPKARVKLSDALNHSFFC 2073
DD G+ +IG+ L RY + G G F VV D R +V VKII+N E + + E+ LK L + DPD KY C+++Y F + H+C+ F+ L +++ L++ + V ++ VR + Q+ A+ + G+ H D+KP+NIL +S V +L DFGSA T + +R YRAPE+I+ + P D+WS+GC ++EL +G +F N E L +M G +P KM R + +FD ++ ++K + RE L S PN +V LF DLL ++L DP R+ L+ AL H F
Sbjct: 164 DDADGYYRVRIGELLDKRYNVYGFSGSGVFSNVVRARDQARGSQEVVVKIIRNNEMMHKTGLKELEFLKKLNDADPDDKYHCLRLYRHFFHKNHLCLVFESLHMNLREVLRKYGQNVGLHIKAVRSYSQQLFLALKLMKRTGILHADIKPDNILVNDSKLMV-----------------KLCDFGSALATGGCDITPYLVSRFYRAPEIIIGSKYDYPIDLWSVGCTIYELHTGKIMFPGKSNNEMLKLMMDYKGKMPNKMIRRGLLKERHFDDSCNFLYYEVDKITQ--REKTTVL--------SAINPNKDVMESLFGYHKLNDEHKRKVNQLKDLLDKILMLDPSKRLSLNQALTHPFIT 499
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk2a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101162379]) HSP 1 Score: 446.047 bits (1146), Expect = 5.835e-149 Identity = 210/346 (60.69%), Postives = 268/346 (77.46%), Query Frame = 1
Query: 1036 IVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
+ V DDE GHL+ + GD L RYEI TLGEGTFG+V++C+D +R VA+KIIKN+EKY+EAA LEINVL+ + EKDPD K+LC++MYDWF+Y+GH+C+SF+LL LS F+FLKEN Y+PY + QVRH+AYQ+C AV FLH++ LTHTDLKPENILFVNSD+ + + KK++ VK++ +R++DFGSATFDHE HST+VSTRHYRAPEVILELGWS PCDVWSIGCI+FE + G TLFQTHDNREHLAMM+RILG +P +M R T K + G+L W+ K+VRENCK L R+ L S + ++ +LFDL+ MLEY+P R+ L+D+L H FF
Sbjct: 163 LSVRDDEEGHLICRSGDVLQERYEIVGTLGEGTFGRVMKCIDHRRGGVSVALKIIKNVEKYKEAARLEINVLEKINEKDPDNKFLCVQMYDWFDYHGHMCLSFELLALSTFDFLKENNYLPYSIGQVRHMAYQICLAVKFLHDSKLTHTDLKPENILFVNSDFTMSYNVEKKREERTVKNTSVRVVDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSHPCDVWSIGCILFEYYLGFTLFQTHDNREHLAMMERILGPVPSRMIRKTRKQKYFYRGRLDWDESSSAGKYVRENCKPL---RRYLLSEAEEHH----QLFDLIESMLEYEPARRLTLADSLKHPFF 501
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk2b (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101158555]) HSP 1 Score: 417.542 bits (1072), Expect = 5.170e-140 Identity = 205/353 (58.07%), Postives = 262/353 (74.22%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKK-QHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQS 2103
D ++GHL+Y+ GD L +RYEI NTLGEGTFGKVV+CLD R ++A+KIIKN EKYR A LEINVL+ + EKDP KY C++M +WFNYNGHICISFQLL LS F+FLK N ++PYP++Q+R +A Q+C AV+FLH+N LTHTDLKPENILFVNS+Y+++ +++KK + + +RLIDFG+ATFD+E HS V+STRHYRAPEVILELGWS PCDVWSIGCI+FE + G TLFQTHDN+EHLAMM+R G +P +M +S+ K + G L WN K +FV+ CK L R+ L S+ + ++ FDL+ RMLEY+P R+ L AL H FF LP N +S
Sbjct: 35 DAKNGHLIYRSGDVLEDRYEIINTLGEGTFGKVVQCLDHGRGGRQIALKIIKNQEKYRNTAKLEINVLEKISEKDPLHKYHCVQMLEWFNYNGHICISFQLLSLSTFDFLKSNNFLPYPLQQIRLMAGQICRAVSFLHDNKLTHTDLKPENILFVNSNYSLVYNAEKKCNEKRINDTTVRLIDFGTATFDYEHHSVVISTRHYRAPEVILELGWSHPCDVWSIGCILFEYYEGFTLFQTHDNKEHLAMMERTHGPLPQRMIQSSRKQKYFCSGHLDWNESSKAGRFVKSKCKPL---RQYLLSHGREHH----HFFDLMERMLEYEPSKRISLHSALEHPFF--LPLNHSGKS 378
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: clk4a (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101161565]) HSP 1 Score: 397.127 bits (1019), Expect = 1.975e-129 Identity = 188/353 (53.26%), Postives = 254/353 (71.95%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF-CRLPSNQR 2094
VEDD GHL+Y GD L RYEI TLGEG FGKVVEC+D + +A+KIIKNI++YREAA+ E+ VLK L D D +Y C++M DWF+Y+GHICI+F+LLGLS ++FLKEN + P+P+E +RH+A+Q+ V FLH+N LTHTDLKPENILFV+S+Y++ + K++ +K+ ++R++DFG+ATFDHE H++VVSTRHYRAPEVIL+LGW CDVWSIGCI+ E + G+TLFQTHD++EHLAMM+R+LG IP K+ T K + +L W+ ++VR++CK L+ Y E +LFDL+ +M+EYDP R+ L AL+H FF C S+ R
Sbjct: 199 VEDDGEGHLIYHSGDMLRARYEIVYTLGEGAFGKVVECIDHANNGELIALKIIKNIDRYREAALSEVEVLKQLNSVDADKRYSCVRMLDWFDYHGHICIAFELLGLSTYDFLKENNFQPFPLEHIRHMAFQIIRGVKFLHKNKLTHTDLKPENILFVDSNYSMEYNREKRRDERTLKNPDVRIVDFGNATFDHEHHTSVVSTRHYRAPEVILDLGWDHSCDVWSIGCILIEYYLGTTLFQTHDSKEHLAMMERVLGPIPAKLLEKTRKRRYVHRSRLDWDGQSSSGRYVRKHCKP-------LKHYMWSKGEDHRQLFDLIEKMMEYDPTKRITLEQALHHPFFSCFYKSSNR 544
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000019341.2 (dual specificity protein kinase CLK2 [Source:NCBI gene;Acc:101170453]) HSP 1 Score: 345.895 bits (886), Expect = 1.822e-111 Identity = 172/355 (48.45%), Postives = 238/355 (67.04%), Query Frame = 1
Query: 1042 VEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKK-KQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQS 2103
+EDDE G L Y G RYE+ + LGEG FG+V++CLD KRK + VAVKI++N E E A LEI VL+ + D D K+ C++M DWF + H+CI F+LLGLS F FL++N+++P+ +EQ+RH+A+++ AV+FLH N LTHTDLKPENILFV+SD+++ K + +S E++++DFG+ATFDH+ H ++VSTRHYRAPEVIL+LGW+Q CDVWS+GC++FE + G TLF +HD EHLAMM +LG IP + + T K +F D +L W+ VRE C+ L + ++ +L DLLS MLEYD R+ L +AL H FF + + Q QS
Sbjct: 89 MEDDEGGQLDYHSGFVFKERYEVVSILGEGAFGRVMKCLD-KRKDEFVAVKILRNFENSYETARLEIAVLEEINSLDDDNKFACVRMLDWFKHKRHVCIVFELLGLSTFEFLRQNDFLPFSVEQIRHMAFRIFRAVSFLHRNKLTHTDLKPENILFVSSDFDLEDDPKTMRVCRKPRSLEVKVVDFGTATFDHQHHQSLVSTRHYRAPEVILDLGWNQSCDVWSLGCVLFEFYFGQTLFPSHDCMEHLAMMQEVLGPIPPHLLKQTGKKHFVQDDRLKWDQQSSSGDCVREPCRPL--------KSIEAESDEEQQLLDLLSCMLEYDTCRRITLEEALWHPFFSPMRAKQSPQS 434
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Match: dyrk4 (dual specificity tyrosine-phosphorylation-regulated kinase 4 [Source:NCBI gene;Acc:101159741]) HSP 1 Score: 182.185 bits (461), Expect = 1.656e-48 Identity = 104/343 (30.32%), Postives = 182/343 (53.06%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIP--YKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFF 2070
DDE G + + D++ R+E+ +G+G+FG+V++CLD K + VA+K+I+N +++ A++E+ +L+ +++KD D + I M ++F + H+CISF+LLG++++ +K+N + + + +R A+ + + LH+ + H DLKPENIL S++ N I+++DFGS+ ++ ++ T + +R YR+PEVIL +S D+WS+GCI+ EL +G LF E +A + +LG P + + S K +FD G N K R N K L K + + L +DP R+ + L H +
Sbjct: 182 DDEHGSYIRVLHDHIAYRFEVLEVIGKGSFGQVLKCLDHKTN-ELVAIKMIRNKKRFHHQALVELKILEVIKKKDKDNLHNVIHMKEYFYFRNHLCISFELLGVNLYELIKKNNFQGFSLALIRRFAHALLRCLQMLHKEKIIHCDLKPENILL----------SQRGPGN------IKVVDFGSSCYEQQRVYTYIQSRFYRSPEVILGHPYSMAIDMWSLGCILAELHTGYPLFPGESEVEQIACIMEVLGMPPNDFVQSASRRKLFFDSKGN-PRNITNSKGKKRRPNSKELSAALKTTDPL----------FLEFIKGCLTWDPTKRMTPDEGLQHQWI 496
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000033729.1 (SMESG000033729.1) HSP 1 Score: 1262.67 bits (3266), Expect = 0.000e+0 Identity = 684/692 (98.84%), Postives = 685/692 (98.99%), Query Frame = 1
Query: 82 MKRQRNDNSQYYTKISKPYSPSPRLKRGRSRELYEDLAKYSSSIFNADPAALLQQLSVVACASQFLDYLKPVSATNSRKSRDRYGVKITEYRRSREISYNDRYARNYDSYDDKQNFKYGSXXXXXXXXXXHKSTSRRKNDGKWERPLSPPHHSYDRYSHRRKHSRTDKDPSYIKQYPSVRKSIKETKTNDFRCSREVILRRNSSSFEKCDQNLDNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXYPNGPEYIKGXXXXXXXXXXXXMSHXXXXXXXXXXXXXPTAYVVNEDRSSKSASGEIHSDSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLISKEQIMIPNIYRF 2157
MKRQRNDNSQYYTKISKPYSPSPRLKRGRSRELYEDLAKYSSS+FNADPAALLQQLSVVACASQFLDYLKPVSATNSRKSRDRYGVKITEYRRSREISYNDRYARNYDSYDDKQNFKYGSNNFSNNTNYNHKSTSRRKNDGKWERPLSPPHHSYDRYSHRRKHSRTDKDPSYIKQYPSVRKSIKETKTNDFRCSREVILRRNSSSFEKCDQNLDNEKIKKIKNKSKKKHKKSKKLPHKSHSSDSKYPNGPEYIKGPRTPSSPPRSPRMSHEKELEEKSIKISLPTAYVVNEDRSSKSASGEIHSDSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLF SYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLISKEQIMIPNIYRF
Sbjct: 1 MKRQRNDNSQYYTKISKPYSPSPRLKRGRSRELYEDLAKYSSSLFNADPAALLQQLSVVACASQFLDYLKPVSATNSRKSRDRYGVKITEYRRSREISYNDRYARNYDSYDDKQNFKYGSNNFSNNTNYNHKSTSRRKNDGKWERPLSPPHHSYDRYSHRRKHSRTDKDPSYIKQYPSVRKSIKETKTNDFRCSREVILRRNSSSFEKCDQNLDNEKIKKIKNKSKKKHKKSKKLPHKSHSSDSKYPNGPEYIKGPRTPSSPPRSPRMSHEKELEEKSIKISLPTAYVVNEDRSSKSASGEIHSDSTEFSTSPDKKQNIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLF-------SYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLISKEQIMIPNIYRF 685
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000041213.1 (SMESG000041213.1) HSP 1 Score: 481.1 bits (1237), Expect = 1.511e-159 Identity = 229/365 (62.74%), Postives = 282/365 (77.26%), Query Frame = 1
Query: 1048 DDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHN-VVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLPSNQRFQSNKHLISKEQIMI 2139
DD+ GHL+Y GD + RY I TLGEGTFGKVVEC+D + +VA+KIIKN+EKYREAA+LEINVLK +QEKDP+ KYL IKM +WF++ GH+CISF+L G SVF+FLKEN Y PYPME VRHI+YQ+CFAV FLH+ LTHTDLKPENILFVNSD ++ +SK+K+ + VVK+SEIRLIDFGSATFDHE HST+VSTRHYRAPEVILELGWS+ CDVWSI CI+FEL++G TLFQTHDN+EHLAMM+RILGH PY+M R + +F GKL W+ D ++VRENC+ L YC N+ +E+FDL+S+MLEY+P R+ L AL+H FF RLP +QR H +S +I +
Sbjct: 393 DDKEGHLIYGHGDMIMGRYRIVKTLGEGTFGKVVECVDNDQSSKRVALKIIKNVEKYREAALLEINVLKVIQEKDPESKYLFIKMLNWFDHYGHMCISFELCGQSVFDFLKENSYSPYPMEHVRHISYQLCFAVKFLHDIHLTHTDLKPENILFVNSDSILVPNSKRKRDDRVVKNSEIRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSESCDVWSIACIIFELYTGYTLFQTHDNKEHLAMMERILGHFPYRMARKSKTSFF-YHGKLDWDFYSPDGRYVRENCRPLL-------RYCTDENQETIEMFDLVSKMLEYEPADRISLGAALSHPFFLRLPPHQRL----HTLSSRRISV 745
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000071751.1 (SMESG000071751.1) HSP 1 Score: 378.252 bits (970), Expect = 2.241e-123 Identity = 186/346 (53.76%), Postives = 247/346 (71.39%), Query Frame = 1
Query: 1033 NIVVEDDESGHLMYKIGDNLHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNV-ISSSKKKQHNVVKSSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPK-DYFDIDGKLIWNPIEKDAKFVRENCKRLFLKRKLLQSYCKPNNEVA-VELFDLLSRMLEYDPKARVKLSDALNH 2061
+ +V D G+L+ K L RY+I LGEGTFG+V +C DLK ++VAVK+IK +EKYREAA+LEI VL+ +++ DP G+ L I D FNY+GH+CI F LLG SVF+FLK N YV YPM QVR++ YQ+ AV+FLH LTHTDLKPENILFVN Y++ S KK +++ + I++ID GSATF+ E H+T+V+TRHYR EVILELGWS PCDVWSIGCI+FEL++G T+F THDN EHLAMM+RILGH+P +MTR + K YFD G+L W+ K+ K+VR K L+ Y ++++ ++LFDL+ MLEY+PK R+ +S++L H
Sbjct: 128 DTIVNRDNDGYLVMKEDQLLKKRYKILKLLGEGTFGRVAQCKDLKNHNNEVAVKVIKAVEKYREAALLEIKVLELIKKTDPQGRKLVIFALDSFNYHGHMCIVFPLLGPSVFDFLKANHYVGYPMRQVRYMTYQISKAVDFLHSLKLTHTDLKPENILFVNGAYDMQYDESTKKNVKILRDASIQIIDLGSATFEDEHHTTIVATRHYRPLEVILELGWSYPCDVWSIGCILFELYTGITMFMTHDNIEHLAMMERILGHLPVRMTRKSKKRKYFDDCGRLKWDGESKEGKYVRGEV-------KPLRRYITRHDDIKELDLFDLIQEMLEYNPKKRITMSESLRH 466
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000065189.1 (SMESG000065189.1) HSP 1 Score: 218.779 bits (556), Expect = 7.180e-63 Identity = 105/248 (42.34%), Postives = 164/248 (66.13%), Query Frame = 1
Query: 1090 LHNRYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHENGLTHTDLKPENILFVNSDYNVISSSKKKQHNVVK---SSEIRLIDFGSATFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKM 1824
+ +R+ LGEGTFGKV+ CLD + +++A+K+ K +EKY++ A EI +L ++++DP G+ + + WF + HI + F G ++N+LK ++ + VRHI++QM AV+FLH + HTD+KPEN+LFV+S+Y I S K + +K S++I LID G+ + +E+ ++ TR+YR PEV LE+GW++ D+WSIGC++FEL+SG +LFQ HD+ EHL MM+ IL P +M
Sbjct: 233 IKDRFFFTGLLGEGTFGKVISCLDQRLNDERIALKVSKRLEKYKKLAKHEIEILVRIRKRDPKGENYVVILKAWFELDCHIIMIFPQYGEDLYNYLKSIDHHGMKLGDVRHISWQMWRAVDFLHGLTIIHTDIKPENLLFVSSEYKYIES--KNSESKIKYPSSTDIVLIDLGNGVYGNERKPRIIVTRYYRPPEVYLEIGWNKSVDIWSIGCVMFELYSGRSLFQCHDDLEHLWMMEYILKEFPEQM 478
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Match: SMESG000078436.1 (SMESG000078436.1) HSP 1 Score: 206.068 bits (523), Expect = 6.225e-58 Identity = 110/332 (33.13%), Postives = 194/332 (58.43%), Query Frame = 1
Query: 1099 RYEINNTLGEGTFGKVVECLDLKRKYDKVAVKIIKNIEKYREAAMLEINVLKFLQEKDPDGKYLCIKMYDWFNYNGHICISFQLLGLSVFNFLKENEYVPYPMEQVRHIAYQMCFAVNFLHEN-GLTHTDLKPENILFVNSDYNVISSSKKKQHNVVKSSEIRLIDFGSA-TFDHEKHSTVVSTRHYRAPEVILELGWSQPCDVWSIGCIVFELFSGSTLFQTHDNREHLAMMDRILGHIPYKMTRSTPKDYFDIDGKLIWNPIEKDAKFVRENCKRL--FLKRKLLQSYCKPNNEVAVELFDLLSRMLEYDPKARVKLSDALNHSFFCRLP 2082
RY LGEGTFG V+ECLD +++ VA+K+ KN+ E + E+++LK + + C + +WF +C+ F G ++++F+K+ ++ P PME ++ IAYQ+ A+ FLHEN L HTDLKPENI+ + Y K + + +I++IDFG+A T K++ V+ TR+YRA EV+L + W+ D WS+GCI++EL +G LF T+++ HLA++D+I+GH+P +MTR+ K + ++G +N + ++ E+ + + K QS+ ++S +++ +P++R ++ + ++ F ++P
Sbjct: 177 RYIFVKDLGEGTFGYVLECLDCEKRRQPVAIKVSKNLLATTEKLLNEVSILKKINDIYNSPNNPCATLIEWFKLEKRLCLVFHRYGDNIYHFMKKRQFKPLPMEFIKQIAYQLLSAILFLHENCDLIHTDLKPENIVLCSPIYITKQERGDKANMLPSKYDIKIIDFGNALTNKGFKYTKVIGTRYYRAVEVMLGVPWNYKIDYWSLGCILYELVTGKILFMTNNDSHHLALIDKIIGHLPEEMTRTCKKAHLFLNGH--FNKAAINDYYLIESAEYIENHFKHSSFQSH---------SFTAMISSLIQINPESRPEMKEFIHSHMFAKVP 497 The following BLAST results are available for this feature:
BLAST of Protein kinase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025633 ID=SMED30025633|Name=Protein kinase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2262bpback to top protein sequence of SMED30025633-orf-1 >SMED30025633-orf-1 ID=SMED30025633-orf-1|Name=SMED30025633-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=693bp MKRQRNDNSQYYTKISKPYSPSPRLKRGRSRELYEDLAKYSSSIFNADPAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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