Ca(2 )/calmodulin-responsive adenylate cyclase

Query:  621 MAILTIIPLVHINCQQCMRPQHMAFLKFSGF-ILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETIT------------KIYKAYPLLTNLLDGNESGKY------SQKI-NQNSFS 1973
            +A+L +  +  +   Q  +   +A L    F +LCC   +              +    G+W+   L++T   +  +   +LLA+    +  +  ++    +V +K+P    + W  L  N LLF+   + G  +  L ++  R AFL AR    SC+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+       P      +S   ++ ++T+++ P H ++        LI+SD   ++  +  T            K++KA    +N++   +  K       S+K+ N++SFS
Sbjct:  103 LALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQ--LLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRP----RLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQAR----SCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVE-------PGYGHERNSFLKTHNIETFFIVPSHRRK----IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFS 553          

Query: 2868 TLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDG--VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            TLPL +   +    K++++ G           T  ++  E S   R+ G  V  +    IV+ + F+  +   +R ++   RL + W  +   +RE+  K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++ME   Y+ I KI+T G T   A+G+ P    ++    S  ++ L   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   +I VT   +  +     + F   G + V   G++++
Sbjct:  738 TLPLAIFFRVSSLPKMILLSG---------LTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQS-YNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEE-VHRLLRRCPYHFVCRGKVSVKGKGEMLT 1051          

Query: 1002 LIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            + G  +  L ++  R AFL AR    SC+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+ G
Sbjct:    1 MYGVFVRILTERSQRKAFLQAR----SCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPG 232          

Query: 1002 LIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            + G  +  L ++  R AFL AR    SC+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+ G
Sbjct:    1 MYGVFVRILTERSQRKAFLQAR----SCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPG 232          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATS 1829
            W  L  N LLF+ + +IG    Y  +   R AF   R ++ + +  +  N + +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++++T   L   Y+V+ G               G+ N     YL+ +HI+   IL  S
Sbjct:  286 WKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLA-----SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPG-------------RGGERN----AYLKEQHIETFLILGAS 556          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVL---------------GTVICTCVIIFGTHELIFTEFSKTYRSDG--------VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSR---LMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            ++ +S  IVRS   S  + I + L +FT  ++N F C ++P  +   +    T           L                 C  P Y   + +   L   V L +    K+ ++                 T+     ++ G H L  +  ++T+  DG        V +KY++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S++  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++        V RS    L    +R  E +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     ++ +   G  D+I VT++ 
Sbjct:  728 LQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASS--NETF--DGLDCPAAGRVALKYMTPVILLVFALALYLHAQQVEST-ARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNAS--TYDQVGRSHITALADYAMRLMEQMKHI-NEHSFNN----FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDL 1132          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATS 1829
            W  L  N LLF+ + +IG    Y  +   R AF   R ++ + +  +  N + +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++++T   L   Y+V+ G               G+ N     YL+ +HI+   IL  S
Sbjct:  286 WKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLA-----SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPG-------------RGGERN----AYLKEQHIETFLILGAS 556          

Query: 3015 VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSR---LMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            V +KY++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S++  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++        V RS    L    +R  E +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     ++ +   G  D+I VT++ 
Sbjct:  839 VALKYMTPVILLVFALALYLHAQQVEST-ARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNAS--TYDQVGRSHITALADYAMRLMEQMKHI-NEHSFNN----FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDL 1079          

Query: 1299 SSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKH---------IKQNSILATSDLIVSDTSDSQHDETITKIYKAYPLLTNLLDGNESGKYSQKINQNSFSQSQTH 1988
            + D V+ +NEL+S+FD   Q L C +++   D Y  ++G P  R +HA  C  +   + +TIKQ+  +  V +++R  VHTG     ++G  +  FD+  DDV +   M     PG V ++KST D L   Y + +    D P++         S    TY++ P           I +NS L+TS  + S  S       + + + A     N      S  +   +  +  ++  T+
Sbjct:  332 AKDLVRTLNELYSKFDRDAQRLQCMRIKFLGDCYYCVSGMPVNRPNHADMCVVMGLEMINTIKQVRIATGVDVNMRIGVHTGSVLCGIMGLRKWQFDIWSDDVTLANHMESAGVPGAVHITKSTKDMLLGDYCI-VDANTDDPHVV--------SYGQPTYHILPDKTSAIERTASIYRNSRLSTSPALQSRMSMKAKVSKMVEFWGAETPFANFTKKKFSASHDPALITDEIARRPTY 561          

Query: 3183 MIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-----DPDHPIESSVDRSRLMTNLLRG-------------AEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSN 3743
            +I+ +LP  V + +L+P R    L++ +++ + V+  SIP++     + + +     +R+LN+++  FD ++    +  + KI+T G T   A G+     D D       +  +   N+  G             A  + +I+   N  + +N F LRIG+ +    +GV+G   P + +WG     A+ +   G+  KIH T++
Sbjct:  817 LIENILPSSVAAKFLSPDRAVNELYARQHENVCVMFASIPNFKDFWSEWDTNRKLECLRLLNEIVCEFDKLLSKPKFSSVEKIKTVGSTYMAAAGLNESEADYDDIYLEKQNSGKYNNNIRHGNMAFRNANLMIEFALAMSQILDALNRDSFQN-FELRIGMSVGPLVAGVIGAQKPQYDIWGNTVNLASRMDTHGEPRKIHATTD 1021          

Query: 1002 LIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEK----LDRLLSCVVPMPILAELKQSIMLRELHG----HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            ++GS++ Y  + + R  F   R+    CV+++M  +K     +++L  V+P  I  E+K+   ++E H     H   +    ++S +  +ICG +  A  + N      D V ++NELF+RFD +     C ++++  D Y  + G PE + +HA +  E+   +   I+ + +   V +++R  +HTG  +  VLG  +  FD+  +DV +   M      G+V ++ +T   L   Y ++ G
Sbjct:  224 VVGSLVYYPTEFVQRKTFHETRK----CVQSRMLLDKEMHRQEKILLAVLPKNIAFEVKKD--MQETHEERMFHKIYIRKYEDISILFADICGFTNLA-SEYN----PKDLVLMLNELFARFDKVASIHQCMRIKILGDCYYCVCGVPEYQKNHAINTVEMGRDMIEAIRLVREMTLVNVNMRVGIHTGKAHCGVLGLKKWQFDVWSNDVTLANQMESGGLAGRVHITDATRSYLKGAYILEEG 456          

Query: 3063 ILVLWKSRILNTFRRLVFQW-------QMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCP--VGVKEPSDVASNIRVLNQLLITFDDVMES----SDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS---VPP 3839
            +LV++ +R      R  F W       Q++M  K E++  ++  +       LP  V  H++  + +   L+        ++  ++  +    +     ++    +R+LN+++  FD +++      +++ I KI+T   T   A G+          D S +    L   E+L ++  E  + +  N F LRIGI++    +GV+G + P + +WG +   A+ +   G   +I VT    + ++P   + F   G + V   G + +   +PP
Sbjct:  744 LLVVFSTRRSELISRYDFIWKLQALDEQLQMKRKHEQNRSVLENI-------LPSHVAKHFVEDATSVSKLYHESRDNACIMFATLTEFDKFYIECDGNNEGVECLRLLNEIISDFDQILDQILDREEFKKIEKIKTISTTYMVASGLAG----RECGDNSHVEAIALFARELLVKL--ESTNIHSFNNFNLRIGINVGPVVAGVIGSDKPHYDIWGNSVNVASRMDSGGVAGRIQVTEEVKSILEPLG-YNFECRGQINVKGKGMMETFFLLPP 1004          

Query: 1176 MLRELHGHLPSVVHL-RNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLP 1727
            M+ E     P  ++L  NVS +  +I G ++ +         + + V L+N+LF RFD L +  G  ++    D Y  +AG PE   DHA    E+   +   I+Q        +++R  +HTG     ++G  R  FD+  +DV +   M      G+V VS++T   L   Y+++ GP  D P
Sbjct:  300 MVPEYRKFRPFTMNLMTNVSILFADIAGFTKMSSNKS-----ADELVNLLNDLFGRFDTLCRLRGLEKISTLGDCYYCVAGCPEPCDDHACRTVEMGLDMIVAIRQFDIDRGQEVNMRVGIHTGKVMCGMVGTKRFKFDVFSNDVTLANEMESSGVAGRVHVSEATAKLLKGLYEIEEGPDYDGP 479          

Query: 3042 VSQIFFAILVLWK-------SRILNTFRRLVFQWQMKMNL-----KREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPD------HPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYD 3788
            +SQ F + L +W+       S +L  F    F+   +M+       R +  ++ +  D+  D LL   + +H +   +     +S  ++T+GVL  SI +W  +  +        +RVLN+++  FD++++  D+  I KI+T G     A G++P+      HP E        +  ++  A  ++ ++   N       F+ ++G+++    +GV+G     + +WG+    A+ +   G L++I V+ +    +    +F F D
Sbjct:  960 LSQDFGSPLFIWELLLDVILSIVLVAFLNYQFETAFRMSFFGDVQARRDTERMQIVRDQA-DWLLNNVIPAHAVESLKTDTK-YSENHETVGVLFASITNWNDMYEENFEGGREFLRVLNEVIGDFDELLDRPDFTHIEKIKTIGPAYMAASGLNPERKKNMLHPKEH-------LYQMVDFALAVQHVLSVFNEDLLNFDFVCKLGLNIGPVTAGVIGTTKLYYDIWGDTVNIASRMYSTGVLNRIQVSQHTREYLLDRYEFEFRD 1217          

Query: 1311 VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLC--DSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPE--GYKVDL 1706
            V L+N+L+  FD +      Y+V    D Y+ ++G PE R DHA    +++  + H +K           L +R  +H+G     V+G+    + L GD V     M     P K+ VS+ TYD L +  G+K++L
Sbjct: 1070 VTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDDHANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLEL 1205          

Query: 1311 VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLC--DSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPE--GYKVDL 1706
            V L+N+L+  FD +      Y+V    D Y+ ++G PE R DHA    +++  + H +K           L +R  +H+G     V+G+    + L GD V     M     P K+ VS+ TYD L +  G+K++L
Sbjct: 1108 VTLLNDLYLAFDGVVDNFKVYKVETIGDAYMVVSGLPERRDDHANQIAQMSLSLLHKVKNFVIRHRPHEQLKLRIGMHSGSVVAGVVGSKMPRYCLFGDTVNTSSRMESNGLPLKIHVSQQTYDILMQEAGFKLEL 1243          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  587 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNAS-IPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1071          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSK----HWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L G+  LV  +  ++       N         +  +  L  + LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A  I L   H  +++         +F+       +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVL-GVVALVFVLCGVMAALSLTFNNAATFHNIFNAIVCGLFAVVLVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYK-------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQ-----CSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVA-SNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  587 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNAS-IPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1071          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L G+  LV  +  ++       N         +  +  L  + LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A   F     S+   L +            +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVL-GVVALVFVLCGVMAALSLTFNNAATFHNIFNAIVCGLFAVVLVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVA---FGIALPSVHISLTVYKIFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLSSQ-----CSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  587 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNA-SIPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1071          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLL--IGLFCLVIGIIEMIP-TFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSK----HWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L  + L  ++ G++  +  TF    N  T    + +I   +  ++ LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A  I L   H  +++         +F+       +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVLGVVALVFVLCGVMAALSLTF---NNAATFHNIFNAIVCGLFAVV-LVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYK-------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLS-----SQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  664 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNA-SIPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1148          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLL--IGLFCLVIGIIEMIP-TFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSK----HWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L  + L  ++ G++  +  TF    N  T    + +I   +  ++ LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A  I L   H  +++         +F+       +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVLGVVALVFVLCGVMAALSLTF---NNAATFHNIFNAIVCGLFAVV-LVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYK-------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLS-----SQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  587 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNA-SIPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1071          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLL--IGLFCLVIGIIEMIP-TFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSK----HWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L  + L  ++ G++  +  TF    N  T    + +I   +  ++ LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A  I L   H  +++         +F+       +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVLGVVALVFVLCGVMAALSLTF---NNAATFHNIFNAIVCGLFAVV-LVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYK-------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLS-----SQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query:  597 VRCWISISMAILTIIPLVHINCQQCMRPQHMAFL-KFSGFILCCAILVSVS-PIWGNFKIDSESFI-TVGLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            V C I  S+ I+T +  + +   Q  +   +A L  F+  +LCC   +++     G    D+ S     G+W+ + +        PV   TLLA+    L  +   I     V +++P    + W  L  N +L +   L G  +    ++  R AFL AR  +   ++ +  NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+ G
Sbjct:   88 VHCVIFTSLFIVTNVKYLQVT--QLQQIARLALLFSFTFALLCCPFPLALGHGTQGTHGPDAPSTTPEQGVWQLMLVTFVAYSLLPVR--TLLAVLFGVLVAASHFIVTATSVTARRP----RVWTPLVANAVLLVGVNLSGVFVRVRTERAQRKAFLQARNCIQQRLQLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANMMEAGGLPGKVHITKATLECLNGDYEVEPG 450          

Query: 3039 IVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDV---GTLIVNHAGQLIS 3830
            +++ + F+  ++   R L+   RL + W  +   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GVL  SIP++    ++   +      +R+LN+++  FD +M+   Y  I KI+T G T   A+G+    P E S  +  +  +L   A+    +    ++ N +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT +    +      G+YD    G + V   GQ+++
Sbjct:  781 VLAMLLFSGALVLHCRQLDLKLRLDYLWATQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLLSNPRNMDLYYQSYSQVGVLFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDALMDKECYRDIEKIKTIGSTYMAAVGLV---PTEGSKVKKSISAHLCTVADYAIEMFDVLDAINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTEDVFRLLS-----GYYDFNCRGQVSVKGKGQMLT 1043          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPN--YGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  +V G++        PP+  Y +     +S++MA+   + +V      C R   H  ++    + L   +L+ V  ++G   +   S  + G+W +++ I  I    PV    + A  +   +  +I  +    +++   F    W  LS N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  119 FQSRKLERLYQRYF---FRLNQ-SSLTMLMGVLVIVCGVMLTFHCIHGPPDVVYAS----VLSVAMALFLALMVV------CNRNGFHQDYMWMVSY-LVIGVLIIVQ-VFGVLMVAPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGGVLSAIHLLTTWRINQDDEFL---WKQLSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLASENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLQYLNGDYEVEPG 521          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTC-------VIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            M+ +S  IV+S   S ++ + T + +F     N F C     ++   KQ   +         H +                 CP P Y  YS +   L   V L +    K+ ++L   +          V +F   +L  T  + T+R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    Y  + KI+T G T   A G+ D  +  E     + L    +   E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D+I VT++ + ++  S  +     G + V   G++ +
Sbjct:  717 MQTVSKKIVQSRTNSTLVGVFTIILVFISAFVNMFSCDTQKLVDCVAKQLNWSSEMVTPCIIHNMSRSVADGLSICPNNTPSCPFPEYFSYSVLLTLLACSVFLQISSIGKLALMLLIQLTFLLLVEWPEVALFDNADLFVTANALTFRVTKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKYRQLEKIKTIGSTYMAASGLNDSTYDKEGRSHITALADYAMHLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTD-LHQVLHSKGYQLECRGVIKVKGKGEMTT 1136          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPN--YGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  +V G++        PP+  Y +     +S++MA+   + +V      C R   H  ++    + L   +L+ V  ++G   +   S  + G+W +++ I  I    PV    + A  +   +  +I  +    +++   F    W  LS N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  119 FQSRKLERLYQRYF---FRLNQ-SSLTMLMGVLVIVCGVMLTFHCIHGPPDVVYAS----VLSVAMALFLALMVV------CNRNGFHQDYMWMVSY-LVIGVLIIVQ-VFGVLMVAPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGGVLSAIHLLTTWRINQDDEFL---WKQLSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLASENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLQYLNGDYEVEPG 521          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTC-------VIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            M+ +S  IV+S   S ++ + T + +F     N F C     ++   KQ   +         H +                 CP P Y  YS +   L   V L +    K+ ++L   +          V +F   +L  T  + T+R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    Y  + KI+T G T   A G+ D  +  E     + L    +   E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D+I VT++ + ++  S  +     G + V   G++ +
Sbjct:  717 MQTVSKKIVQSRTNSTLVGVFTIILVFISAFVNMFSCDTQKLVDCVAKQLNWSSEMVTPCIIHNMSRSVADGLSICPNNTPSCPFPEYFSYSVLLTLLACSVFLQISSIGKLALMLLIQLTFLLLVEWPEVALFDNADLFVTANALTFRVTKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKYRQLEKIKTIGSTYMAASGLNDSTYDKEGRSHITALADYAMHLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTD-LHQVLHSKGYQLECRGVIKVKGKGEMTT 1136          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPN--YGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  +V G++        PP+  Y +     +S++MA+   + +V      C R   H  ++    +++   +++    ++G   +   S  + G+W +++ I  I    PV    + A  +   +  +I  +    +++   F    W  LS N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  158 FQSRKLERLYQRYF---FRLNQ-SSLTMLMGVLVIVCGVMLTFHCIHGPPDVVYASV----LSVAMALFLALMVV------CNRNGFHQDYMWMVSYLVIGVLIIV--QVFGVLMVAPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGGVLSAIHLLTTWRINQDDEFL---WKQLSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLASENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLQYLNGDYEVEPG 560          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTC-------VIIFGTHEL-------IFTEFSK-----------TYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            M+ +S  IV+S   S ++ + T + +F     N F C     ++   KQ   +         H +                 CP P Y  YS +   L   V L +    K+ ++L   +          V +F   +L       +F E  +           T+R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    Y  + KI+T G T   A G+ D  +  E     + L    +   E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D+I VT++ + ++  S  +     G + V   G++ +
Sbjct:  756 MQTVSKKIVQSRTNSTLVGVFTIILVFISAFVNMFSCDTQKLVDCVAKQLNWSSEMVTPCIIHNMSRSVADGLSICPNNTPSCPFPEYFSYSVLLTLLACSVFLQISSIGKLALMLLIQLTFLLLVEWPEVALFDNADLFVTANALVFNETLQWSNFNTTTEQCTFRVTKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKYRQLEKIKTIGSTYMAASGLNDSTYDKEGRSHITALADYAMHLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTD-LHQVLHSKGYQLECRGVIKVKGKGEMTT 1193          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVI-------GIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRE--LHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF  + +S+ L     ++ L C V+       G+ ++  TF+            +  + AI+ I+ L+ +  +      HM  + +   +L  A+ V V  ++   +  SE     G+W T++ I  I    PV    + A  I   +  +I  ++   L+   VF    W  L  N L+F  S ++G    Y  +   R AF   RE + + + ++  N++ +RLL  V+P  +  E+K  I  ++  +  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T + L   Y V+ G
Sbjct:  151 FQSEKLERLYQRYFFRLNQSS-LTMLMAVLVLVCAVMLGFHCAGGMCQL--TFV------------LVFTAAIVLILTLMVVCNRNSFHQDHMWIVCYLLILLVLAVQV-VGVLFVKPRSASE-----GIWWTVFFIHVIYTLLPVR---MRAAVITGIILSAIHVLISWRLNDMDVFL---WKQLVSNVLIFSCSNIVGVCTHYPAEGSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVALEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYDVEPG 553          

Query: 3015 VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNL-LRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            VP+K ++ +V  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++     ++     R + +  +R  + +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     A+ +   G  ++I VT++ + ++  S  +     G + V   G++++
Sbjct:  870 VPLKIVTPVVITVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDQFRQLEKIKTIGSTYMAASGLNDSTYDKAGRSHIRALADYAMRLMDQMKYI-NEHSFNN----FKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERIQVTTD-LYQVLSSYNYTLEYRGVVKVKGKGEMMT 1137          

Query:  597 VRCWISISMAILTIIPLVHI-NCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETIT------------KIYKAYPLLTNLLDGNESGKY------SQKI-NQNSFSQSQTHKS 1994
            V C I +S+ I+T +  + +   QQ ++   +    FS   LCC   +      G + ++       GLW+ + +        PV   TLLA+   F+     II     +  KK     + W  L  N +LF+   L G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+       P      +S    + ++T+++ P H ++        LI+SD   ++  +  T            K++KA    +N++   +  K       S+K+ N++SFS +  H +
Sbjct:   86 VHCIIFLSLFIVTNVKYLQVTQLQQIVKLTLLFGFTFS--FLCCPFSL------GAYGLEPPVSSEQGLWQLMLVTFVAYALLPVR--TLLAIVFGFMVSVSHIIVTATSISPKK----KRLWRTLVVNAILFVSVNLSGVFVRILTERAQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKNTLECLNGDYEVE-------PGYGHERNSFLKKHNIETFFIVPSHRRK----IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVIHNT 543          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            C    Y   S +  TL L + L +    K+V++L   I   VI      L  + + KT   D   ++    I++ + F+  +   SR ++   RL + W ++   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++ME   Y+ I KI+T G T   A+G+ P    ++       ++ L   +  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT + +  I  S  + F   G + V   G++++
Sbjct:  700 CDTAHYTFLSCVVGTLSLAIFLRISSFPKMVLLLFVTILYIVI------LEISGYRKTLGGDTSYMRGYEPILAILLFSCSLALHSRQVDLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKECYKDIEKIKTIGSTYMGAVGLVPTTGTKAKKSIYSHLSTLADFSIEMFDVLDEINYQS-YNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTED-VHRILKSCNYEFVCRGKVSVKGKGEMLT 1028          

Query:  597 VRCWISISMAILTIIPLVHI-NCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETIT------------KIYKAYPLLTNLLDGNESGKY------SQKI-NQNSFSQSQTHKS 1994
            V C I +S+ I+T +  + +   QQ ++   +    FS   LCC   +      G + ++       GLW+ + +        PV   TLLA+   F+     II     +  KK     + W  L  N +LF+   L G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+       P      +S    + ++T+++ P H ++        LI+SD   ++  +  T            K++KA    +N++   +  K       S+K+ N++SFS +  H +
Sbjct:   89 VHCIIFLSLFIVTNVKYLQVTQLQQIVKLTLLFGFTFS--FLCCPFSL------GAYGLEPPVSSEQGLWQLMLVTFVAYALLPVR--TLLAIVFGFMVSVSHIIVTATSISPKK----KRLWRTLVVNAILFVSVNLSGVFVRILTERAQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKNTLECLNGDYEVE-------PGYGHERNSFLKKHNIETFFIVPSHRRK----IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVIHNT 546          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            C    Y   S +  TL L + L +    K+V++L   I   VI      L  + + KT   D   ++    I++ + F+  +   SR ++   RL + W ++   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++ME   Y+ I KI+T G T   A+G+ P    ++       ++ L   +  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT + +  I  S  + F   G + V   G++++
Sbjct:  710 CDTAHYTFLSCVVGTLSLAIFLRISSFPKMVLLLFVTILYIVI------LEISGYRKTLGGDTSYMRGYEPILAILLFSCSLALHSRQVDLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKECYKDIEKIKTIGSTYMGAVGLVPTTGTKAKKSIYSHLSTLADFSIEMFDVLDEINYQS-YNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTED-VHRILKSCNYEFVCRGKVSVKGKGEMLT 1038          

Query:  795 GLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETIT------------KIYKAYPLLTNLLDGNESGKY------SQKI-NQNSFSQSQTHKS 1994
            GLW+ + +        PV   TLLA+   F+     II     +  KK     + W  L  N +LF+   L G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+       P      +S    + ++T+++ P H ++        LI+SD   ++  +  T            K++KA    +N++   +  K       S+K+ N++SFS +  H +
Sbjct:   11 GLWQLMLVTFVAYALLPVR--TLLAIVFGFMVSVSHIIVTATSISPKK----KRLWRTLVVNAILFVSVNLSGVFVRILTERAQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKNTLECLNGDYEVE-------PGYGHERNSFLKKHNIETFFIVPSHRRK----IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVIHNT 409          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            C    Y   S +  TL L + L +    K+V++L   I   VI      L  + + KT   D   ++    I++ + F+  +   SR ++   RL + W ++   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++ME   Y+ I KI+T G T   A+G+ P    ++       ++ L   +  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT + +  I  S  + F   G + V   G++++
Sbjct:  573 CDTAHYTFLSCVVGTLSLAIFLRISSFPKMVLLLFVTILYIVI------LEISGYRKTLGGDTSYMRGYEPILAILLFSCSLALHSRQVDLKLRLDYLWAVQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKECYKDIEKIKTIGSTYMGAVGLVPTTGTKAKKSIYSHLSTLADFSIEMFDVLDEINYQS-YNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTED-VHRILKSCNYEFVCRGKVSVKGKGEMLT 901          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISI-SMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF  + +S+ L      + L CLV+         ++   +G     ++S+ ++A+   + L+ +  +      +M  + +    L  A+L +V  + G   +   S  + G+W +++ I  I    PV    + A  +   +  S+  I+   L+   +F    W  LS N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++ +T   L   Y+V+ G
Sbjct:   34 FQSAKLERLYQRYFFQMNQSS-LTMLMGALVLVCLVM--------LIFHCTHGEPQVVYVSVLAVAMALFLSLMVVCNRNGFHQDYMWIVSY----LVIAVLFAVQ-VLGVLMVTPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGLILSSLHLIISWRLNLTDIFL---WKQLSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITSATLKYLNGDYEVEPG 436          

Query: 3141 KREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            ++EE  +L     R++  +LPK V +H+L        L+  SCE   +   S+   S   V ++  ++    +R+LN+++  FD+++    ++ + KI+T G T   A G+ D  +  E     + L    ++  E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D I VT++ 
Sbjct:  495 EKEEMEQLQAYNRRLLHNILPKDVAAHFLAREHRNDELYYQSCECVAVMFASICNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKFKQLEKIKTIGSTYMAASGLNDTTYDKEGKTHITALADYAMKLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPDCIQVTTDL 694          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISI-SMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF  + +S+ L      + L CLV+         ++   +G     ++S+ ++A+   + L+ +  +      +M  + +    L  A+L +V  + G   +   S  + G+W +++ I  I    PV    + A  +   +  S+  I+   L+   +F    W  LS N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++ +T   L   Y+V+ G
Sbjct:  128 FQSAKLERLYQRYFFQMNQSS-LTMLMGALVLVCLVM--------LIFHCTHGEPQVVYVSVLAVAMALFLSLMVVCNRNGFHQDYMWIVSY----LVIAVLFAVQ-VLGVLMVTPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGLILSSLHLIISWRLNLTDIFL---WKQLSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITSATLKYLNGDYEVEPG 530          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCC-------INSPQLNATYKXXXXXXXXXXXSDSHL----------LCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPI-----------------KYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            ++ +S  IV+S   S ++ I+T L +FT    N F C           +LN +YK       +       +          LC  P Y  YS +   L   V L +    K+ ++L   I   VI+ G   ++F  +      + +PI                 K+++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L        L+  SCE   +   S+   S   V ++  ++    +R+LN+++  FD+++    ++ + KI+T G T   A G+ D  +  E     + L    ++  E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D I VT++ 
Sbjct:  725 LQGVSRKIVQSRTNSTLIGILTILLVFTSAFVNMFACNHRSLTDCAGQELNISYKFVNVCHLRMLNYSLSMDSPPCDSDKPLCNFPEYFNYSILLSLLACSVFLQISSIGKLALMLFIQILYIVIVEGPEVVLFDNYDLLVTVNALPINGTGDIEECLPSSKIALKFVTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATGEKEEMEQLQAYNRRLLHNILPKDVAAHFLAREHRNDELYYQSCECVAVMFASICNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKFKQLEKIKTIGSTYMAASGLNDTTYDKEGKTHITALADYAMKLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGLPDCIQVTTDL 1127          

Query:  936 PVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            P    + W  L  N LLF    + G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+ G
Sbjct:  203 PAKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPG 456          

Query: 2868 TLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPI--KYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            TLPL + L +    K++++ G           T  ++  E S   +  G  +  +    I++ + F+  +   +R ++   RL + W  +   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++M+   Y+ + KI+T G T   A+G+ P     +    S  +  L   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   +I VT      +   S + F   G + V   G++++
Sbjct:  737 TLPLAIFLRVSSLPKMILLSGLT---------TSYILVLELSGYTKVGGGALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKSISSHLCTLADFAIDMFDVLDEINYQS-YNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKRCS-YQFVCRGKVSVKGKGEMLT 1050          

Query:  795 GLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRE--LHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            G+W T++ I TI    PV    + A  +   +  ++   + +  + +  F  K    L  N L+F  + ++G    Y  +   R AF   RE + + + ++  N++ +RLL  V+P  +  E+K  I  ++  +  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T + L   Y+V+ G
Sbjct:  329 GIWWTVFFIYTIYTLLPVR---MRAAVLSGVLLSALHLAISLHTNSQDQFLLKQ---LVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPG 624          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGT-------VICTCVIIFGTHELIFTEFSKTYRSDG----------VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            C  P Y  YS +   L   V L +    K+V++L         V    V +F   +L+ T  +  + ++G          V +K ++ I+  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S++  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++     +S+ D++   T++   A+   +++ +    N    N F ++IG+++    +GV+G   P + +WG     A+ +   G  D+I VT++ M ++  ++ +     G + V   G++++
Sbjct:  905 CNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIEFIYVLIVEVPGVTLFDNADLLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLN-----DSTYDKAG-KTHIKAIADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTD-MYQVLAANTYQLECRGVVKVKGKGEMMT 1252          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            W  L  N +LF+ +  IG    Y  +   R AF   R ++ + +  +  N + +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++++T   L   Y+V+ G
Sbjct:  284 WKQLGANVVLFLCTNAIGVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPG 531          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVY--------IPYSTIWVTLPLIVMLA----LPETFKVVIVLG---TVICTCVIIFGTHELIFTEFSKTYRSDG--------VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSR---LMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            ++ +S +IVRS + S  + I + L +F   ++N F C ++P      +    T           L                 C  P Y        +  S++++ +  I  LA    L  T+ V+++LG    +     ++ G H L     S     DG        V +KY++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S++  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++        V RS    L    +R  E +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     ++ +   G  D+I VT++ 
Sbjct:  726 LQRLSRNIVRSRVHSTAVGIFSVLLVFISAIANMFTCNHTPIRTCAARMLNLTPADVTACHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNVLLSLLASSVFLHISSIGKLAMTFILGFTYLVLLLLGPPAAIFDNYDLLLGVHGLA----SSNETFDGLDCPAVGRVALKYMTPVILLVFALALYLHAQQVEST-ARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNAS--TYDQVGRSHITALADYAMRLMEQMKHI-NEHSFNN----FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDL 1130          

Query: 2682 LLIITSLGIFTLIVSNSFCCINS-----PQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKT-YRSDGV--PIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASN----IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSN 3743
            L I+T+  I T+ V N F   NS     P  NA+         Q     +  L  LP +I YS I   +   V L +    K++I++  ++   +I+  TH  +   +S+  ++  G+   +K + ++   IFF I +L   R    + RL F W+ K   +REE   +      +++ +LP  V  H+L  S     L+   Y  + V+  SIP +     +  SDV       +R+LN+++  FDD++    + G+ KI+T G T   A G+      E + +  R   ++    E    +V + ++ N    N F LR+GI+     +GV+G   P + +WG     A+ +   G LDKI VT  
Sbjct:  686 LTIVTTAIILTMAVFNMFFLSNSEETTLPTANASNANVSVPDNQTAILHARNLFFLPYFI-YSCILGLISCSVFLRVNYELKMLIMMVALVGYNIILLHTHAHVLDAYSQVLFQRPGIWKDLKTMGSVSLSIFF-ITLLVLGRQSEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTE--SDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHAQEPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEE 1049          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG------------HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGP-RLDLPYIXXXXXXX------GDSNRMDTYYLRPKH 1799
            W  L+ N ++FI   L G+   +L +  L+  +      + S ++ +    + +RLL  ++P  I  E+K  I+ R L G            H   V    NVS +  +I G +R A     G     + V ++NELF +FD + +E  C ++++  D Y  ++G P +  +HAK+C ++   +   IK++ D+  V +++R  VH+G     V+G  +  +D+   DV +   M     PG+V +S  T + L   YKV+ G   +  PY+   +  +          R   +  RP+H
Sbjct:  193 WQILA-NVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQR-LQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPG-----ELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRH 485          

Query:  981 LLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVH------LRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +LF+     G  ISYL  +  R AFL  R  + + +  +  N++ +RL+  V+P  ++ E+   +   E   HL    H        NVS +  ++ G +     + +    + + V+++NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +  TI+ +    +  +D+R  +H+G     VLG  +  FD+   DV I   +     PG++ +SK+T D L   Y V+ G
Sbjct:  324 VLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRLETENQRQERLVLSVLPRFVVLEMINDMTNVE-DEHLQHQFHRIYIHRYENVSILFADVKGFT-----NLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRRDHAHCCVEMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLDCLNGDYNVEEG 566          

Query: 2823 LCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRS--DGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPV--GVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHV 3734
            +C  P Y  ++ +   +   V L L    K+ ++L  +    ++    +  +F  +     S  D +  K  S ++  +F  + V +  + L    RL F W+++   +  E  +L    + M+  +LP  V  H+L   R+   L+S  Y  +GV+  SIP +       +  +     +R+LN+++  FD+++    ++ I KI+T G T     G+ P+   +   D+   +  L   +  L   +QE N K+  N F LRIGI   +  +GV+G   P + +WG+    A+ +   G   +I V
Sbjct:  827 ICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLLLMAMF-LLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEK--QQCEDKWGHLCALADFSLALTESIQEIN-KHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQV 1130          

Query: 2346 SYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPVGVK-EPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRS--RLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            S  I+   +   K+  +D    R+   F  S ME ++    +     A+  SL  ++   +L    L +T++LLL+FL  F+W+  +L+L+L +++K+I   I  S    + + I T + I+++   N F C++    +              Q+DSH  C LP Y+  S  +  L + V L LP  FK ++VLG      + I  +H+ IF  +     +  +P+  IS     IF  I +L   R++    RL F WQ++ + +++E   L  +  R++  LLP  V +H+L+   RN M L+   Y  +GV+  S+P++     + + SD     +R+LN+++  FD++++   + GI KI+T G T    +G+ P++ I+ +   S  R MT L+   + ++  +QE NS +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G      VT   +  +   S F F   GT+ V   G +++
Sbjct:  664 SQAINARSVDCDKSEHVD----RLTLRFRQSDMEREYHKDFDLGFTTAMGCSLLLLILGAALQVTALPRTLILLLLFLFAFIWVSAILMLLLAVRLKWIIWDISESFSLRMAITIFTVILIYSVGQVNVFTCVSDHPCSGN-------GTTSFQNDSHRKCSLPQYVSLSAAFAFLSVSVFLRLPIIFKSLLVLGMGTIYGLFIELSHQNIFECYDNRVNA-SIPLHLISLARIAIFM-IAILVHGRLVEGTARLDFLWQLQASQEKKEMDVLQESNKRILHNLLPAHVAAHFLDAQFRNNMELYHQSYAKVGVIFASVPNFNEFYTEMDGSDQGLECLRLLNEIIADFDELLKEDRFRGIDKIKTVGSTYMAVVGLIPEYKIQPNDPNSVRRHMTALIEYVKAMRHSLQEINSHS-YNNFMLRVGINIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPGYSQVTQEVVDSL-VGSHFEFRCRGTIKVKGKGDMVT 1148          

Query:  417 INPFAFKNINLERIYAKYFSLVYRSTQLARFFLL--IGLFCLVIGIIEMIP-TFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGN-FKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSK----HWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHG--HLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +N   F+N  LE +Y +Y      + +L RF +L  + L  ++ G++  +  TF    N  T    + +I   +  ++ LV + C   ++  H+  L +   +   +I V   P  G+ F +D++  +  G+W+ ++++       P+  +  +A  I L   H  +++         +F+       +  L  N ++FI   + G V++ + ++  R  FL  R  + S +E +  NEKL+RLL  V+P  +  ++K  I L  + G  H   +    NVS +  +I G +  +         + + V+L+NELF RFD L  +  C ++++  D Y  ++G PE R DHAK   E+   +   I  + ++ +V+L++R  +HTG     VLG  +  FD+  +DV +   M     PG+V V+++T D L   Y+V+ G
Sbjct:   13 LNTLRFENDELECLYQRY------TLKLQRFSVLGVVALVFVLCGVMAALSLTF---NNAATFHNIFNAIVCGLFAVV-LVLLQCS-VIKDHHLPTLCYGILLFTASICVVSMPTLGSVFPVDTKEVMAEGVWQIVFVVFLAYAMMPLQIWEAVAFGIALPSVHISLTVYK-------IFTDALRYLEYNQLIANIVIFIGVNVAGLVVNIMMERAQRRTFLDTRNCIASRLEIQDENEKLERLLLSVLPQHVAMQMKNDI-LSPVAGQFHRIYIQKHENVSILFADIVGFTVLS-----SQCSAQELVRLLNELFGRFDQLAHDNHCLRIKILGDCYYCVSGLPEPRKDHAKCAVEMGLDMIDAIATVVEATDVILNMRVGIHTGRVLCGVLGLRKWQFDVWSNDVTLANHMESGGEPGRVHVTRATLDSLSGEYEVEAG 429          

Query:  621 MAILTIIPLVHINCQQCMRPQHMAFLKFSGF-ILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTI-FXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETIT------------KIYKAYPLLTNLLDGNESGKY------SQKI-NQNSFS 1973
            +A+L +  +  +   Q  +   +A L    F +LCC   +              +    G+W+   L++T   +  +   +LLA+    +  +  ++    +V +K+P    + W  L  N LLF+   + G  +  L ++  R AFL AR    SC+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+       P      +S   ++ ++T+++ P H ++        LI+SD   ++  +  T            K++KA    +N++   +  K       S+K+ N++SFS
Sbjct:  103 LALLVVTNVRSLQVPQLQQVGQLALLFSLTFALLCCPFALGGPARGSAGAAGGPATAEQGVWQ--LLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTATLVPAKRP----RLWRTLGANALLFVGVNMYGVFVRILTERSQRKAFLQAR----SCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVE-------PGYGHERNSFLKTHNIETFFIVPSHRRK----IFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFS 553          

Query: 2868 TLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDG--VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            TLPL +   +    K++++ G           T  ++  E S   R+ G  V  +    IV+ + F+  +   +R ++   RL + W  +   +RE+  K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++ME   Y+ I KI+T G T   A+G+ P    ++    S  ++ L   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   +I VT   +  +     + F   G + V   G++++
Sbjct:  738 TLPLAIFFRVSSLPKMILLSG---------LTTSYILVLELSGYTRTGGGAVSGRSYEPIVAILLFSCALALHARQVDIRLRLDYLWAAQAEEEREDMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMEKDFYKDIEKIKTIGSTYMAAVGLAPTSGTKAKKSISSHLSTLADFAIEMFDVLDEINYQS-YNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEE-VHRLLRRCPYHFVCRGKVSVKGKGEMLT 1051          

Query:  936 PVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            P    + W  L  N LLF+   + G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+ G
Sbjct:  206 PAKRPRLWRTLGANALLFLGVNVYGIFVRILAERAQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPG 459          

Query: 2868 TLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMIPNNLVPICSDESIISIGGRRNSLTVVMASGEPINHYMMNSTPVVPHNAT------ASLMSSNPLVMPRNGAIPPGMS 4130
            TLPL + L +    K++++   V+ T  I+     L  + ++K   +  +  +    I++ + F+  +   +R ++   RL + W  +   +R++  K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++M+   Y+ + KI+T G T   A+G+ P    ++    S  ++ L   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   +I VT      +   S + F   G + V   G++++               + L  +T  +GS   +    + S+  +   G  R  L   +A+G P         PV P           +L  S     P    +PPG S
Sbjct:  740 TLPLAIFLRVSSLPKMILL--AVLTTSYILV----LELSGYTKAMGAGAISGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMEKVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTKAKKCISSHLSTLADFAIEMFDVLDEINYQS-YNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLRRGS-YRFVCRGKVSVKGKGEMLT---------------YFLEGRTDGNGSQTRS----LNSERKMYPFG--RAGLQTRLAAGHP---------PVPPAAGLPVGAGPGALQGSGLAPGPPGQHLPPGAS 1130          

Query:  936 PVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            P    + W  L  N LLF    + G  +  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T   L   Y+V+ G
Sbjct:  203 PAKRPRLWRTLGANALLFFGVNMYGVFVRILTERSQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPG 456          

Query: 2868 TLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPI--KYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            TLPL + L +    K++++ G           T  ++  E S   +  G  +  +    I++ + F+  +   +R ++   RL + W  +   +R++  ++ +   R++  LLP  V  H+L  +   M+L+   Y  +GV+  SIP++    ++   +      +R+LN+++  FD++M+   Y+ + KI+T G T   A+G+ P     +    S  +  L   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   +I VT      +   S + F   G + V   G++++
Sbjct:  737 TLPLAIFLRVSSLPKMILLSGLT---------TSYILVLELSGYTKVGGGALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKSISSHLCTLADFAIDMFDVLDEINYQS-YNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLKRCS-YQFVCRGKVSVKGKGEMLT 1050          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATS 1829
            W  L  N LLF+ + +IG    Y  +   R AF   R ++ + +  +  N + +RLL  V+P  +  E+K+ I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++++T   L   Y+V+ G               G+ N     YL+ +HI+   IL  S
Sbjct:  286 WKQLGANVLLFLCTNVIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKKEDMMFHKIYIQKHDNVSILFADIEGFTSLA-----SQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPG-------------RGGERN----AYLKEQHIETFLILGAS 556          

Query: 2631 MKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLL-----------------CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVL---------------GTVICTCVIIFGTHELIFTEFSKTYRSDG--------VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSR---LMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            ++ +S  IVRS   S  + I + L +FT  ++N F C ++P  +   +    T           L                 C  P Y   + +   L   V L +    K+ ++                 T+     ++ G H L  +  ++T+  DG        V +KY++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S++  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++        V RS    L    +R  E +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     ++ +   G  D+I VT++ 
Sbjct:  728 LQRLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRSCAARMLNLTPADITACHLQQLNYSLGLDAPLCEGTMPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLAMIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASS--NETF--DGLDCPAAGRVALKYMTPVILLVFALALYLHAQQVEST-ARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEERFRQLEKIKTIGSTYMAASGLNAS--TYDQVGRSHITALADYAMRLMEQMKHI-NEHSFNN----FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDL 1132          

Query: 1002 LIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDA---------VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVR-ILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLD------LPYIXXXXXXXGDSNRMDTYYLRPK 1796
            LIG +I+    +     FL A           M   KL RL  C+VP P+  +L    +   L    P V++LRNV+F++ E+ GLS  +    + +  +++          +  +N++++ FD L Q   CY+VR++ ++YL +AGYPETRVDHA+SC +L   +   I ++ + + V L++R  VHTG  Y  VLG SR+ FDL+GDDV  + R       P +V+ S+ST++QLPEG++ + GP         +P      S+  +   M+TY+++P+
Sbjct:  539 LIGQLIAVWTSRHRYRLFLTASYTQAIIFRLHMTESKLHRLSKCLVPAPLADDLVNDFINGHLSWSSPLVIYLRNVTFLSAELVGLSNLSSNLASTLKSNTNINHELICQQFISFINDIYTCFDYLAQNESCYRVRLNANEYLCIAGYPETRVDHARSCIDLGLNMLKIIGEISERSHVQLELRVSVHTGTAYAIVLGRSRLGFDLIGDDVTYVSRLKYAAYRPCRVLTSRSTFNQLPEGFRGEAGPIFGYPNPVIIPTNESIKSNHHNQTTMETYFVQPR 819          

Query: 1002 LIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDA---------VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVR-ILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLD------LPYIXXXXXXXGDSNRMDTYYLRPKHI 1802
            LIG +I+    +     FL A           M   KL RL  C+VP P+  +L    +   L    P V++LRNV+F++ E+ GLS  +    + +  +++          +  +N++++ FD L Q   CY+VR++ ++YL +AGYPETRVDHA+SC +L   +   I ++ + + V L++R  VHTG  Y  VLG SR+ FDL+GDDV  + R       P +V+ S+ST++QLPEG++ + GP         +P      SS  +   M+TY+++P+ I
Sbjct:  539 LIGQLIAVWTSRHRYRLFLTASYTQAIIFRLHMTESKLHRLSKCLVPAPLADDLVNDFINGHLSWSSPLVIYLRNVTFLSAELVGLSNLSSNLASTLKSNTNINHELICQQFISFINDIYTCFDYLAQNESCYRVRLNANEYLCIAGYPETRVDHARSCIDLGLNMLKIIGEISERSHVQLELRVSVHTGTAYAIVLGRSRLGFDLIGDDVTYVSRLKYAAYRPCRVLTSRSTFNQLPEGFRGEAGPIFGYPNPVIIPTNESIKSSHHNQTTMETYFVQPRTI 821          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQ-KMLRNAFLYAREFLNSCVENK---MANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARG--------------DG-NGISFSSDA--VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDS--NRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETITKIYKAYPLLTNLLDGNESGKYSQKINQNSFSQSQTHKSLDYSDTNEKG 2024
            W   + N L F+ + L+G  ++ L++    R  F+     L+S   ++   +   KLD +   +VP P+ A+L+Q  +        P V++LRNVSF++ E+ G    A                DG  GI+  S    +  +N+L S+ + + +  GCY V +HP + L +AGYP+ RVDHA SC +LA  I+  +  + +SA V L +R  VHTG  Y AV G S + FDLLG DV  LR +     PG+V+VS+ST+DQLPEGY+ ++GP         S +++ D+  +  +T+Y++P+ +  +S  ++  L+  D             +  +P LT  + G+       ++ +++ + S TH  LD+  + E+G
Sbjct:  315 WRGFAVNLLSFLCANLVGYQLARLKELAQWRCLFV----VLSSSARSRHLQLVQSKLDIVSRSLVPAPLAADLEQDFISGVCSWTSPLVIYLRNVSFLSAELVGFCTSATDSSDTRACAERELVVDGPGGITGPSPGHVISFLNQLLSQVNSISEAHGCYPVHLHPSEILCVAGYPDVRVDHAHSCVQLALEIRRLVSSIANSARVGLQLRVAVHTGEAYAAVFGKSMLAFDLLGPDVVFLRRLRSATLPGRVLVSRSTFDQLPEGYEGEIGPFF---AAKSSSTNTADTAVSAPETFYVQPRKMT-DSKNSSPSLLGGD-------------HCRWPCLTQ-VSGSTLATCFARLARSAGAASSTHLPLDFLFSAEEG 671          

Query: 2403 SISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYR---------------SDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDR---MIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPV-GVKEPSDVASNIRVLNQLLITFDDVMESSD-YEGITKIRTAGETAWYAIGIDP---DHPIESSVDRSRL--MTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEA 3680
            S++ V   F     E+++  Q +   G A+L +L  +L   SL A +L +T++LLL+F++ F WIG++L+++L  ++K +  +I  S +  V+++I + L ++ +  +N FCC ++     TY    Q           L CPLP +I  S     + + V  +LP   K+ +++       + +  TH  +F+      R               S G    ++  +V    F+IL+   SR     +R  FQW+ +     E  H + +  +    ++  LLP+ V  H+ + + RN ++L++ EY+ +G+L  ++P W P  G + P  V  +IRVLN ++   D++++ +D ++ + K+RT GE    A+G++P   D+P       S+L  +T L++ A++++R V E N+   E+R  +R+GI +  GF GVVGG+ P F +WG+A
Sbjct:  706 SMNPVTLKFSTQAKENEYHRQEDHTFGAAMLAALFILLISASLQASVLPRTMLLLLLFMIAFTWIGMMLMVLLAARLKCLEFNIQSSFVIRVVVIITSVLFVYAVSQANVFCCRSTVGNRTTYGPILQDSDNSL----ELQCPLPDFIYLSGTLCLILVAVFASLPSFIKLFLLVAVSTTFGLTVAVTHRPLFSLVDSDVRGLASLSGLAASAHDMSAGPVPTFVWGLVCLTAFSILIFVHSRFHEFAQRQEFQWKSQ---SAENQHDMFLVKEASCCLLKNLLPQHVALHFTDTTYRNPVDLYAQEYQLLGILWANLPDWQPAPGTEAPLLVQESIRVLNDVICELDELIQRADRHQELVKVRTVGENYVVAVGMNPQLQDNPA------SKLFHLTGLVQLAQLMRRRVAELNATLYEDRIRMRVGIDLGPGFCGVVGGSRPVFDIWGQA 1144          

Query:  420 NPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPI-W-GNFKIDSESFITV--GLWETIWLIITISCFYP-----------VTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANE----KLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISF-SSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEG-YKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHI 1802
            N  AF + ++ER+Y KY   + R+  L+RF  L+   CL++ +  +   F +  +Y   V    + +     +   +H    + MRP+H +       +L   I  +  P+ W     +  +   T+  GLW+  + +  + C  P           V     LA +  L     +       +++K +  S +W +L  + L+ + + L G+ +   +  +LR +FL  +    +C+ N++  +    KL+RL+  VVP  +  +++   +       +  V     +S +   I GL++         SF +SDAVKLMN++F R D L  E   ++VR+  D+Y +  G+P    +HA         +   I  L + +++ L+ R  +++GV Y A+LG  R+ +D++G+ V I R +L    PG++++SKSTY +L +   +V+ GP LD P      ++ G   +++T  +RP+ +
Sbjct:  124 NSDAFVDWSVERLYRKYAFRLERA-MLSRF--LLTYVCLLLALTSIDYAFGHRFSYKAAVYVASASAFLFAAV--FLH---SRLMRPEHTSTGCALVLLLVSLIAATAFPVSWVSASTVQQQQIFTMADGLWQVAFAVFAVYCLLPGQLLATALYGSVLSLCYLACSAVLTRQQLVEPSRADSVARKHITES-YWTSLIASSLVLLCANLGGACLQRFRDSLLRRSFLETK----ACIANQLQLDDETYKLERLVQSVVPSDLTDDMRADCLHGNFGWKVAQVNQTPYMSLMCASISGLTKFP------ASFPASDAVKLMNQVFCRLDQLAYEHQAFRVRIQGDEYTAAIGFPHECAEHATLAVRFGQVLLEMIGNLSECSQLPLEARVGINSGVAYAALLGKCRLTYDVMGEQVVIARRLLQACPPGRILLSKSTYLELADADLRVEPGPLLDRP-----GANGGVRTKLETVIVRPRQL 581          

Query: 2403 SISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYR---------------SDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDR---MIDILLPKFVVSHYLNPS-RNYMNLFSCEYKTIGVLSVSIPSWCPV-GVKEPSDVASNIRVLNQLLITFDDVMESSD-YEGITKIRTAGETAWYAIGIDP---DHPIESSVDRSRL--MTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEA 3680
            S++ V   F     E+++  Q +   G A+L +L  +L   SL A +L +T++LLL+F++ F WIG++L+++L  ++K +  +I  S +  V+++I + L ++ +  +N FCC ++     TY    Q           L CPLP +I  S     + + V  +LP   K+ +++       + +  TH  +F+      R               S G    ++  +V    F+IL+   SR     +R  FQW+ +     E  H + +  +    ++  LLP+ V  H+ + + RN ++L++ EY+ +G+L  ++P W P  G + P  V  +IRVLN ++   D++++ +D ++ + K+RT GE    A+G++P   D+P       S+L  +T L++ A++++R V E N+   E+R  +R+GI +  GF GVVGG+ P F +WG+A
Sbjct:  707 SMNPVTLKFSTQAKENEYHRQEDHTFGAAMLAALFILLISASLQASVLPRTMLLLLLFMIAFTWIGMMLMVLLAARLKCLEFNIQSSFVIRVVVIITSVLFVYAVSQANVFCCRSTVGNRTTYGPILQDSDNSL----ELQCPLPDFIYLSGTLCLILVAVFASLPSFIKLFLLVAVSTTFGLTVAVTHRPLFSLVDSDVRGLASLSGLAASAHDMSAGPVPTFVWGLVCLTAFSILIFVHSRFHEFAQRQEFQWKSQ---SAENQHDMFLVKEASCCLLKNLLPQHVALHFTDTTYRNPVDLYAQEYQLLGILWANLPDWQPAPGTEAPLLVQESIRVLNDVICELDELIQRADRHQELVKVRTVGENYVVAVGMNPQLQDNPA------SKLFHLTGLVQLAQLMRRRVAELNATLYEDRIRMRVGIDLGPGFCGVVGGSRPVFDIWGQA 1145          

Query:  420 NPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPI-W-GNFKIDSESFITV--GLWETIWLIITISCFYP-----------VTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANE----KLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISF-SSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEG-YKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHI 1802
            N  AF + ++ER+Y KY   + R+  L+RF  L+   CL++ +  +   F +  +Y   V    + +     +   +H    + MRP+H +       +L   I  +  P+ W     +  +   T+  GLW+  + +  + C  P           V     LA +  L     +       +++K +  S +W +L  + L+ + + L G+ +   +  +LR +FL  +    +C+ N++  E    KL+RL+  VVP  +  +++   +       +  V     +S +   I GL++         SF +SDAVKLMN++F R D L  E   ++VR+  D+Y +  G+P    +H          +   I  L + +++ L+ R  +++GV Y A+LG  R+ +D++G+ V I R +L    PG++++SKSTY +L +   +V+ GP LD P      ++ G   +++T  +RP+ +
Sbjct:  125 NSDAFVDWSVERLYRKYAFRLERA-MLSRF--LLTYVCLLLALTSIDYAFGHRFSYKAAVYVASASAFLFAAV--FLH---SRLMRPEHTSTGCALVLLLVSLIAATAFPVSWVSASTVQQQQIFTMADGLWQVAFAVFAVYCLLPGQLLATALYGSVLSLCYLACSAVLTRQQLVEPSRADSVARKHITES-YWTSLIASSLVLLCANLGGACLQRFRDSLLRRSFLETK----ACIANQLQLEDETYKLERLVQSVVPSDLTDDMRADCLHGNFGWKVAQVNQTPYMSLMCASISGLTKFP------ASFPASDAVKLMNQVFCRLDQLAYEHQAFRVRIQGDEYTAAIGFPHECTEHTTLAVRFGQVLLEMIGNLSECSQLPLEARVGINSGVAYAALLGKCRLTYDVMGEQVVIARRLLQACPPGRILLSKSTYLELADADLRVEPGPLLDRP-----GANGGVRTKLETVIVRPRQL 582          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSE-SFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRE--LHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF  + +S+ L     +I L C V+          YP          ++ S+AI  ++ L+    +      HM       +++C A++  +  +     I       + GLW T++ I  +    PV     +A  +      ++ +I ++   K     +  W  +  N L+F  + ++G    Y  +   R AF   RE + + + ++  N++ +RLL  V+P  +  E+K  I  ++  +  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T + L   Y V+ G
Sbjct:  169 FRSEKLERLYQRYFFRLNQSS-LTMLMAVIALVCAVMLCFHCAGGPCYPA-------LVLTFSLAIALVLALMLACNRSAFHQDHM-------WLVCYAVIAVLLVLQVVGVILVRPRSASDGLWWTVFFIYVVYTLLPVRMRAAVATGV------ALAAIHVVGSWKLNEQDALLWRQIVSNVLIFSCTNIVGVCTHYPAEGSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYDVEPG 571          

Query: 2361 EDDISLKKTSEIDL-SISRVRN--------TFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCC--------------INSPQLNATYKXXXXXXXXXXXSDSHLL-----CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVII-------FGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNL-LRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            ED++       ID  SI R+R+        TF +  +E K+  Q +   G  +  +    LFI+ L  ++  +                     +  + ++ +S  IV+S L S ++ + T + +F     N F C              I    +NA + +           DS        C  P Y     +   L   V L +    K+ ++L   I   +II       F   +L+    +       VP+K ++ +V  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++     ++     R + +  +R  + +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     A+ +   G  ++I VT++ + ++  S  +     G + V   G++++
Sbjct:  660 EDEVDEFLGRAIDARSIDRLRSEHVKKFLLTFREPDLEKKYSKQVDSRFGAYVACASLVFLFISPLTFILFGQ---------------------LFPVPLQNLSKRIVQSRLNSALVGVFTIVLVFLSAFINIFTCSTDDLKRCLGREFNITPSSVNACHVRSSAFNYSLWSQDSLCYSTAPACNFPEYFSSCVLLSLLACSVFLQMSSIGKLFLMLFIEILYVLIIEVPEVSLFDNGDLLVIANAICVTDSRVPLKIMTPVVITVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDQFRQLEKIKTIGSTYMAASGLNDSTYDKAGRSHIRALADYAMRLMDQMKYI-NEHSFNN----FKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERIQVTTD-LYQVLNSYNYSLECRGVVKVKGKGEMMT 1159          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSE-SFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRE--LHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF  + +S+ L     +I L C V+          YP          ++ S+AI  ++ L+    +      HM       +++C A++  +  +     I       + GLW T++ I  +    PV     +A  +      ++ +I ++   K     +  W  +  N L+F  + ++G    Y  +   R AF   RE + + + ++  N++ +RLL  V+P  +  E+K  I  ++  +  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T + L   Y V+ G
Sbjct:  169 FRSEKLERLYQRYFFRLNQSS-LTMLMAVIALVCAVMLCFHCAGGPCYPA-------LVLTFSLAIALVLALMLACNRSAFHQDHM-------WLVCYAVIAVLLVLQVVGVILVRPRSASDGLWWTVFFIYVVYTLLPVRMRAAVATGV------ALAAIHVVGSWKLNEQDALLWRQIVSNVLIFSCTNIVGVCTHYPAEGSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYDVEPG 571          

Query: 3015 VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNL-LRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            VP+K ++ +V  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    +  + KI+T G T   A G++     ++     R + +  +R  + +K I  EH+  N    F ++IG++M    +GV+G   P + +WG     A+ +   G  ++I VT++ + ++  S  +     G + V   G++++
Sbjct:  928 VPLKIMTPVVITVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDQFRQLEKIKTIGSTYMAASGLNDSTYDKAGRSHIRALADYAMRLMDQMKYI-NEHSFNN----FKMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPERIQVTTD-LYQVLNSYNYSLECRGVVKVKGKGEMMT 1195          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAIL-------VSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  LV G++         P+        +S++MA+  ++ +V      C R   H  ++    +++   ++       + VSP     +  SE     G+W +I+ +  I    PV   + +   I       + +I L+   +  +     W  L  N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  139 FRSAKLERLYQRYF---FRLNQ-SSLTMLMGVLVLVCGVMLAFHCVHGHPDVA--YASVLSVAMALFLVLMVV------CNRNGFHQDYMWMVSYLVMAVLVVVQVFGVLMVSP-----RSASE-----GVWWSIFFVYIIYTLLPVRMRSAVLSGI------VLSTIHLVTAWRLNLEDQFLWKQLCANGLVFLCTNIIGICTHYPAEVSQRQAFKETRGYIQARIHLQRENQQQERLLLSVLPRHVAMEMKAHINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAWENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITKATLQYLNGDYEVEPG 541          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICT-------CVIIFGTHELIFTE-----FSKTY---RSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            CP P Y  YS +   L   V L +    K+ ++L   +          V ++   +L+ T      F+ T+   R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S     ++  ++    +R+LN+++  FD+++    ++ + KI+T G T   A G++      S+ DR    +++L  A+   R+ ++    N    N F ++IG+++    +GV+G   P + +WG     A+ +   G  D I VT++ 
Sbjct:  819 CPFPEYFTYSVLLTLLACSVFLHISSIGKLALMLLIQLIFLLLLEWPLVDLYDNADLLVTANALSGFNGTHCHERMSKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYTELEANNEGVECLRLLNEIIADFDEIISEDQFKQLEKIKTIGSTYMAASGLNA-----STYDREG-RSHILALADYAMRLREQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDCIQVTTDL 1137          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAIL-------VSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  LV G++         P+        +S++MA+  ++ +V      C R   H  ++    +++   ++       + VSP     +  SE     G+W +I+ +  I    PV   + +   I       + +I L+   +  +     W  L  N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  139 FRSAKLERLYQRYF---FRLNQ-SSLTMLMGVLVLVCGVMLAFHCVHGHPDVA--YASVLSVAMALFLVLMVV------CNRNGFHQDYMWMVSYLVMAVLVVVQVFGVLMVSP-----RSASE-----GVWWSIFFVYIIYTLLPVRMRSAVLSGI------VLSTIHLVTAWRLNLEDQFLWKQLCANGLVFLCTNIIGICTHYPAEVSQRQAFKETRGYIQARIHLQRENQQQERLLLSVLPRHVAMEMKAHINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAWENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITKATLQYLNGDYEVEPG 541          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICT-------CVIIFGTHELIFTE-----FSKTY---RSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            CP P Y  YS +   L   V L +    K+ ++L   +          V ++   +L+ T      F+ T+   R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S     ++  ++    +R+LN+++  FD+++    ++ + KI+T G T   A G++      S+ DR    +++L  A+   R+ ++    N    N F ++IG+++    +GV+G   P + +WG     A+ +   G  D I VT++ 
Sbjct:  819 CPFPEYFTYSVLLTLLACSVFLHISSIGKLALMLLIQLIFLLLLEWPLVDLYDNADLLVTANALSGFNGTHCHERMSKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYTELEANNEGVECLRLLNEIIADFDEIISEDQFKQLEKIKTIGSTYMAASGLNA-----STYDREG-RSHILALADYAMRLREQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDCIQVTTDL 1137          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAIL-------VSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  LV G++         P+        +S++MA+  ++ +V      C R   H  ++    +++   ++       + VSP     +  SE     G+W +I+ +  I    PV   + +   I       + +I L+   +  +     W  L  N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  139 FRSAKLERLYQRYF---FRLNQ-SSLTMLMGVLVLVCGVMLAFHCVHGHPDVA--YASVLSVAMALFLVLMVV------CNRNGFHQDYMWMVSYLVMAVLVVVQVFGVLMVSP-----RSASE-----GVWWSIFFVYIIYTLLPVRMRSAVLSGI------VLSTIHLVTAWRLNLEDQFLWKQLCANGLVFLCTNIIGICTHYPAEVSQRQAFKETRGYIQARIHLQRENQQQERLLLSVLPRHVAMEMKAHINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAWENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANQMEAGGKAGRIHITKATLQYLNGDYEVEPG 541          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICT-------CVIIFGTHELIFTE-----FSKTY---RSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            CP P Y  YS +   L   V L +    K+ ++L   +          V ++   +L+ T      F+ T+   R   V +K ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S     ++  ++    +R+LN+++  FD+++    ++ + KI+T G T   A G++      S+ DR    +++L  A+   R+ ++    N    N F ++IG+++    +GV+G   P + +WG     A+ +   G  D I VT++ 
Sbjct:  819 CPFPEYFTYSVLLTLLACSVFLHISSIGKLALMLLIQLIFLLLLEWPLVDLYDNADLLVTANALSGFNGTHCHERMSKVSLKVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYTELEANNEGVECLRLLNEIIADFDEIISEDQFKQLEKIKTIGSTYMAASGLNA-----STYDREG-RSHILALADYAMRLREQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDCIQVTTDL 1137          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDL-PYIXXXXXXXGDSNRMDTYYLRPKHIKQ 1808
            W  L  N  LF+   L G+ I  L ++  R AFL AR    +C+E+++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++KST D L   Y+V+ G   D   Y+          + ++TY++ P H ++
Sbjct:   13 WLKLLANVSLFVSVNLSGAFIRVLTERAQRKAFLQAR----NCIEDRLRLEDENEKQERLLMSLLPRHVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKSTLDCLNGDYEVEPGNGKDRNSYLR--------KHNIETYFIVPSHRRK 285          

Query: 3021 IKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            +K    +++ + F   +   SR L+   RL + W  +   +R +  ++     R++  LLP  V  H+L  +   M+L+   Y  +GVL  SIP++    ++   +      +R+LN+++  FD++++   ++ I KI+T G T   A+G+ P    ++       ++++   A  +  +V E N ++  N F+LR+GI +    +GV+G   P + +WG     A+ +   G   KI V+ + + +I   S + F   G + V   G++++
Sbjct:  584 MKAYEPVLTILLFICAMGLHSRQLDLKLRLDYLWASQAEDERGDMERVKNDNKRILFNLLPAHVAQHFLQSNPRNMDLYYQSYSQVGVLFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELLDKECFKDIEKIKTIGSTYMAAVGLVPTSGTKAKCSIISHLSSVADFAMEMFDVVDEINYQS-YNDFVLRVGISVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGLPGKIQVSED-VYKILKQSNYEFTCRGKVTVKGKGEMLT 853          

Query:  966 LSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            L  N L+F+ + + G    Y  +   R AF   RE + + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:   12 LVANALVFVCTNMAGVCTHYPTEVAQRQAFHETRECIKARLRTQKENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLIKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLRYLNGDYEVEAG 256          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELH-GHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            W  L  N +L + +   G  +    +++ R+ F    E +   +     NEK +RLL  ++P  +  EL+Q  +    H  H   +    NVS +  +I G +  A         + + VKL+NELFS+FD L  E  C ++++  D Y  ++G    + DHA  C ++   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T D L   Y+V+ G
Sbjct:  164 WPKLLVNAVLLVSACACGGAVRIFTERVQRSTFRRTWESVRQRLLLDDENEKQERLLVSLLPRHVAIELRQDFLKPPNHIFHKVYIQRHENVSILFADIVGFTGMA-----SQCTAQELVKLLNELFSKFDELATENHCRRIKILGDCYYCVSGLALAKADHAHCCVKMGLDMIDTIDLVAEAMEVRLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANAMEAGGLPGKVHITKATLDGLRGDYEVEPG 410          

Query: 2841 YIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGV-------PIKYISAI-VSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASN----IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHN--SKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMI 3917
            Y  YS I   +   V L +    KV+ +L  V+   VI+  TH  +F  +++      +        +K + +I +   FF +LVL  +R    + RL F W+ K   +REE   +      +++ +LP  V  H+L   R   +L+   Y+ + V+  SIP +      + SDV       +R+LN+++  FD+++    + G+ KI+T G T   A G++     E+  +  R   ++    E    ++ + +  +K+  N F LR+GI+     +GV+G   P + +WG +   ++ +   G L KI VT    ++I  +  +     G + V   G+L             TF V     ++LS G++I
Sbjct:  509 YFLYSCILGLVSCSVFLRVNHELKVLTLLAAVVGYNVILLHTHHGVFDAYTEALYHPSLVRPGVLKDVKVMGSIWLIVFFFTLLVL--ARQNEYYCRLDFLWKQKFKKEREEIETMENLNRVLLENVLPAHVAEHFLTHHRKNEDLYHQSYECVCVMFASIPDF--KEFYQESDVNKEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNAAVGQENGQEPERQYAHIGIMVEFAMALMGKLDVINKHSFNNFRLRVGINHGPVIAGVIGAQKPQYDIWGNSVNVSSRMDSTGVLGKIQVTEE-TSDILQTLGYNCQCRGMIKVKGKGEL------------KTFFVVTEMTRSLSQGNVI 864          

Query: 1116 DRLLSCVVPMPILAELKQSIMLR--------ELHGHLPS---------VVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            +RLL  V+P  I  E+K  I+ R        +    LP          V   ++VS +  +I G +R A          ++ V  +N+LF +FD + ++  C ++++  D Y  ++G P +   HAK+C ++   +   IK++  +  V +++R  VH+G     V+G  +  +D+   DV +   M     PG+V ++++T + L   Y+V+ G
Sbjct:    2 ERLLLSVLPAHIALEMKAEIIQRLKGPFCGQQQQQLLPENSNNFHNLYVRRHKSVSILYADIVGFTRLASD-----CSPAELVHTLNQLFGKFDQIAKDNDCMRIKILGDCYYCVSGLPISLPSHAKNCVKMGIDMCEAIKKVRYATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITEATLEHLHGAYEVEEG 211          

Query: 1311 VKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            V+L+N+LF RFD L +  GC ++    D Y  +AG PE R DHA  C E+   +   I+Q C      +D+R  VHTG     +LG  R  FD+L +DV +   M  +   GKV VS++T   L E Y ++ G
Sbjct:  347 VRLLNDLFGRFDKLCEVTGCEKISTLGDCYYCVAGCPEPRTDHAACCVEMGLGMIAAIEQFCRDNRETVDMRVGVHTGTVLCGILGMKRFKFDVLSNDVNLANMMEQLGVAGKVHVSEATALCLDERYTMEDG 479          

Query: 3087 ILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVT-SNFMAEIDPSSKFGFYDVGTLIVNHAGQL 3824
             LN    + ++     N++ E H + I  +    D+LL   +  H  +  +   + +S  ++ +GV+  SI ++     +         RVL++L+   D ++    Y GI KI+T G T   A G++   P   + D    +  L   A  +  IV++ N       F LRIG +     +GV+G   P + +WG+    A+ +   G   ++ V+  ++    D   +F +   GT+ V   GQ+
Sbjct:  929 FLNREFEVAYRLNYHGNVEAELHQRKIQHMKNQADLLLHNIIPGHVADQLKVQPH-YSKNHEDVGVIFASIVNFSEFYEENYEGGKECYRVLHELMSDLDQLLARDHYGGIEKIKTIGATYMAASGLNVPEP--RAGDAHAHLRTLFEFARDMMSIVEDFNKDMLWFNFRLRIGFNHGPLTAGVIGTTKPLYDIWGDTVNIASRMDSTGVDCRVQVSQESYHVLCDMGYQFDYR--GTVNVKGKGQM 1170          

Query:  966 LSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSI---MLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            L GN LLFI + + G    Y  +   R AFL  R  + + +  +  N+  +RLL  V+P  +  E+K  I   + +    H   +    NVS +  +I G +  +         +   +K +NEL++RFD L  E  C ++++  D Y  ++G P+ R DHA SC E+   +   I  + D+ +V L++R  VH G  +  VLG  +  +D+  DDV I   M     PG+V ++K   D L   Y+V+ G
Sbjct:  254 LVGNLLLFICANITGVFTHYPTEISQRQAFLETRRCIEARLTIQKENQNQERLLLSVLPRYVAMEMKDDIESGISQNSQFHKIYIQRHENVSILFADIEGFTVLSSQ-----CTAQSLIKTLNELYARFDQLAVENHCLRIKILGDCYYCVSGLPDPRPDHAHSCIEMGLAMIDAISFVRDATQVNLNMRVGVHMGKVHSGVLGLVKWQYDVWSDDVTIANHMESGGLPGRVHITKEVLDCLNGDYEVEEG 499          

Query: 2352 QIDEDDISLKKTSEIDL-SISRVRN--------TFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFI-------SGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQ--------LNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVII-------FGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILN-TFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNY-MNLFSCEYKTIGVLSVSIPSWCPVG-----VKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPG 3857
            Q  ED+++    S ID  SI R+R         TF +   E  +  + ++             LFI     L+L +  + L +FL +F+ + +  LL++  K  F+       S  I +S +   I+  I  +G++   V N F C   P          N T      +    Q    +  C  P Y+ +    V +   V L L    K  ++    I   +++       F  H+  F +F        +    +S ++  IF  IL L     L+    RL F W+++   +++E  +L     +++  +LP  V  H+L    N   +L+   Y++   ++V   + C        +    +    +R+LN++L  FD+++    ++ I KI+T GET   A GI P+   +  +     +  +   A  +KR +++ N  +  N F ++IG++     +GV+G + P + +WG+    A+ +   G+ + I VT   M EI  +  + F   G + V   G++++     W+ G
Sbjct:  518 QDTEDEVNEFLGSSIDARSIERLRKEYVQPILLTFKNPAKEELYSQERDRMFKSYTSCVFLVYLFILGTQLLVLPRNYVTLAVFLSIFLIVAITYLLVVSEKFSFLPESLTNLSSTICQSRVICRIIASILIIGLYVAAVGNLFGCDEPPTPEFTKIFLNNETKLVCNASRYPPQLGVENQSCDYPQYVTFCVTLVMIGCAVFLQLSTVLKFSLLTVMAIVYILLVQYVAKNSFLRHD--FLQFCGLGSGHFIEWSDLSILIVVIF--ILALTAHGYLHEQISRLDFLWKLQATEEKKEMEQLREYNKKLLYNILPVHVAQHFLGHKANKNEDLY---YQSCDKVAVMFSNICNFSDFYTELDANGEGVECLRLLNEILADFDELLSEPQFQCIEKIKTIGETYMAASGIKPES--QEKLATLNHICTMADFAMAMKRKLEDIN-LHSFNNFAMKIGLNFGPVVAGVIGAHKPQYDIWGDTVNVASRMYSTGKDNHIQVTKA-MYEILSTRGYTFDCRGLVAVKGKGKMVTY----WLLG 1042          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSK-TYRSDG---VPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEP--SDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMIPNNLVPICSDESIIS--IGGRRNSLTVVMASGE----PINHYMMNSTPVVPH------NATASLMSSNPLVMPRNGAIPPGMS 4130
            C  P Y  Y+ I + + + V++ L    KV++++G +I   +I     + +F  + K  Y + G   VP  Y S++V  + F IL L   ++  T  RL+F W+M+ + K++E                                +L+S  YK + V+  SIP++     ++   +     IR+LN+++  FD+V+    + G+ KI+T   T   A G+ P+       + S+ + +++  A  L+  +   N ++  N+F+LR+GI      +GV+G   P + +WG     A+ ++  G+   I +T+     I     F F   G + V   GQLI+               ++   K  S    + +N+  + SD   ++  IG   +++  V+++ E     + H   N+  V  +      NA A   +   +   RNG   PG+S
Sbjct:  776 CEYPQYFSYNGILILVGISVLVQLSHALKVMLMIGVLIAYWIINLVRQDKLFVNYDKYVYFNSGSTFVPKMYFSSVVLALTFIILALHGRQVERT-ARLLFLWKMEADEKKKE--------------------------------DLYSHSYKRVSVMFASIPNFSEFYSEDNINNGGVECIRLLNEVITDFDEVLADPRFLGVEKIKTISSTYMAASGLRPE---SEDAEESQNLVDIVDFALTLRDKLDFINQESF-NQFVLRVGICQGPIVAGVIGAKKPHYDIWGNTVNVASRMETTGKAGCIQITAQTYETI-KDKDFVFVYRGAVRVKGKGQLIT--------------YYLTGRKNTSQHVYVVSNVECVVSDVEYVASNIGHVASNVECVVSNVEYVASNVGHVASNAECVASNSGCIVSNAVAVFWTDEIMDKYRNG---PGIS 1173          

Query:  966 LSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINV-EICGLSRGARGDGNGISFSSDAVKL---MNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVM-LDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            L  N L+F+ + ++G++  ++  +  R + L  RE L   +     N++  RLL  V+P  +  E+ +     E  G+     +     FI   + C +          +S    A +L   +NELF+ FD L  +  C ++++  D Y  ++G  ++  +HA     +   +   I  + +   V  L++R  +HTG+    VLG  +  F+   +DV +   M     PG+V +S+ T + + + ++V+ G
Sbjct:  270 LVANTLVFVCANILGAIDYHIADRKQRRSVLETRESLEVKLTLDAQNQQQRRLLLSVLPKHVAEEMTKDF---EGDGNPALTDNAFKKLFIRTHDTCSILFADIVGFTELSSKCTAEQLIVTLNELFANFDKLAAKNHCLRIKILGDCYYCISGLDDS-CNHALCAVNMGLDMVEHIAHVREEKGVKSLNMRVGIHTGMVLAGVLGQRKWQFEAWSNDVTLANHMESGGIPGRVHISEPTLNSIKDYFEVEDG 518          

Query: 1164 KQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            K  ++ R    H      + NVS +  +I G ++ +         +   V+L+N+LF RFD L +   C ++    D Y  +AG P+   +HA  C E+   +   IK+  +  +  +D+R  VHTG     ++G  R  FD+  +DV +   M     PG+V ++++T   L + Y V+ G
Sbjct:  274 KAKMVFRPFQMH-----RMENVSILFADIVGFTKMSSNKS-----ADQLVRLLNDLFGRFDRLTEYNHCEKISTLGDCYYCVAGCPKPTPNHATYCVEMGLDMLEQIKEFDNDTDNDVDMRVGVHTGTVLCGIVGTKRFKFDVWSNDVTLANRMETAGLPGRVHITEATVGFLRDQYIVENG 445          

Query: 3141 KREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTA-GETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSN 3743
            K+ + HK     D ++  L PK V S  L  S +Y    S  Y   GV+  SI ++     +        IRVLN+L+  FD+++++ +Y  + KI+T  G T     G++ +  I   +     +  L+  A  +  +V   N      +F LRIG +     +GV+G     + +WG+    A+ +   G  +KI V+ +
Sbjct:  868 KKSQVHK--QQADWLLLSLFPKHV-SEALKTSDHY----SMNYNNAGVMFASIVNFSDFYEENFEGGKECIRVLNELVGDFDELLDNIEYMEVEKIKTVNGSTFMAGAGLNQEDNIRREIHPYEHLKQLVEFALEMFNVVDRFNEHMLGFKFKLRIGFNAGPVTAGVIGTTKLLYDIWGDTVNLASRMDSTGVPEKIQVSES 1062          

Query: 1122 LLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQEL--GCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTY 1673
            LL  V+P  +  EL+ +  ++     + +++    V F   +IC  S+             + V L+N ++++FDML        Y+V    D Y++++G PE    HA+S   +A  ++H  + +    +  + ++  +H+G     V+G+    + L G+ V +        APG+V +++ TY
Sbjct:    1 LLYSVLPPSVANELRHNRPVQAERAEMVTLLFSGIVDF--AQICKNSK-----------PMEIVMLLNNIYTKFDMLTDPSINDVYKVETVGDKYMAVSGLPERCAFHARSICNMALDMKHVTQSIIHKGD-KIQIKIGIHSGEVVAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTY 172          

Query: 1065 REFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQEL--GCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPE 1688
            R+  N+  E K      D+LL  V+P  +  EL+ +  ++     + +++    V F   +IC  S+             + V L+N ++++FDML        Y+V    D Y++++G PE    HA+S   +A  ++H  + +    +  + ++  +H+G     V+G+    + L G+ V +        APG+V +++ TY  L E
Sbjct:  484 RQTHNALAEKKQLT---DQLLYSVLPPSVANELRHNRPVQAERAEMVTLLFSGIVDF--AQICKNSK-----------PMEIVMLLNNIYTKFDMLTDPSINDVYKVETVGDKYMAVSGLPERCAFHARSICNMALDMKHVTQSIIHKGD-KIQIKIGIHSGEVVAGVVGHKTPRYCLFGNTVNLTSRTETTGAPGQVNITEFTYRCLLE 676          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTN-VRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQ 1808
            F    LE ++  Y   + +++ L    +LI      + ++E++       + G++ V C I +S+ I+T +  + +   Q +    + F  F+   LCC   +      G   ++  +    G+W+ I +        PV   TLLA+ + L +S S + +    ++ K   + K W  L  N +LF    L G  +  L ++  R AFL AR    +C+E ++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV +++ST + L   Y+V+ G   +              + ++T+++ P H ++
Sbjct:   38 FDCKELESLFQNYNLKLEQTSTLKALAVLI-FMSFTLAVVELLSGPSLTISKGSHPVHCVIFLSLFIVTNVKYLQVTQLQQIVNLTLLF-GFTFSFLCCPFSL------GAMGMEPPTSPEQGVWQLILVTFVAYALLPVR--TLLAVLLGLMVSISHLIVTATSVTVK---TQKLWRTLVANTVLFTSVNLSGLFVRILTERAQRKAFLQAR----NCIEERLRMEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVNLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITRSTLECLNGDYEVEPGNGHERSAFL-------QKHEIETFFIVPSHRRK 473          

Query: 2988 FSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYL--NPSRNYM--------------NLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLIS 3830
            F +T       I+    I+S + F   +   SR L+   RL F W ++   +R+   K+ +   R++  LLP  V  H+L  NP RN +              +L+   Y  +GVL  SIP++    ++   +      +R+LN+++  FD++M+   Y+ I KI+T G T   A+G+ P    ++       ++ +   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT +    ++  S +     G + V   G++++
Sbjct:  765 FRRTAGGGSFHIRGFEPILSLLLFVSALALHSRQLDLKLRLDFLWAVQAEEERDGMEKVKLDNRRILFNLLPAHVAQHFLMSNP-RNMVSQANRQAGMQTDKQDLYYQSYAQVGVLFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKECYKDIEKIKTIGSTYMAAVGLVPTIGTKAKKSVHDHLSTIADYAIEMFDVLDEINYQS-YNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVTEDVYRLLN--SNYDLVCRGKISVKGKGEMLT 1059          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTN-VRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKM----ANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQ 1808
            F    LE ++  Y   + +++ L    +LI      + ++E++       + G++ V C I +S+ I+T +  + +   Q +    + F  F+   LCC   +      G   ++  +    G+W+ I +        PV   TLLA+ + L +S S + +    ++ K   + K W  L  N +LF    L G  +  L ++  R AFL AR    +C+E ++     NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV +++ST + L   Y+V+ G   +              + ++T+++ P H ++
Sbjct:   38 FDCKELESLFQNYNLKLEQTSTLKALAVLI-FMSFTLAVVELLSGPSLTISKGSHPVHCVIFLSLFIVTNVKYLQVTQLQQIVNLTLLF-GFTFSFLCCPFSL------GAMGMEPPTSPEQGVWQLILVTFVAYALLPVR--TLLAVLLGLMVSISHLIVTATSVTVK---TQKLWRTLVANTVLFTSVNLSGLFVRILTERAQRKAFLQAR----NCIEERLRMEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVNLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITRSTLECLNGDYEVEPGNGHERSAFL-------QKHEIETFFIVPSHRRK 473          

Query: 2988 FSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSN 3743
            F +T       I+    I+S + F   +   SR L+   RL F W ++   +R+   K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GVL  SIP++    ++   +      +R+LN+++  FD++M+   Y+ I KI+T G T   A+G+ P    ++       ++ +   A  +  ++ E N ++  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT +
Sbjct:  765 FRRTAGGGSFHIRGFEPILSLLLFVSALALHSRQLDLKLRLDFLWAVQAEEERDGMEKVKLDNRRILFNLLPAHVAQHFLMSNPRNMDLYYQSYAQVGVLFASIPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKECYKDIEKIKTIGSTYMAAVGLVPTIGTKAKKSVHDHLSTIADYAIEMFDVLDEINYQS-YNEFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVPGKIQVTED 1017          

Query:  282 EGFTFLDEQRRKTTDFCPIICCSQLIDNYLSTDEWCNFFKCGSESINPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTN-VRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQ 1808
            E   F   Q+R+ T  CP       +D     DE                F +  LE ++  Y   + +++ L    +LI +    + ++E++ +     + G+N V C + +S+ I+T +  + +   Q +    + F  F+  +LCC   +++    G  +    +    G+W+ + + +      PV   TLLA+   + ++ S   +     + +     + W  L  N +LF    L G  +  L ++  R  FL AR  +   +  +  NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+       P       S    + ++T+++ P H ++
Sbjct:    7 EEMPFARVQKRRRTGHCP---APAPLDAIACEDE----------------FNSHELEALFQSYNLKLEQTSTLKALAVLI-VAASSMTLMELLSSPRLTLSKGSNPVHCVVFLSLFIVTNVKYLQVTQLQQIAKLALLF-SFTFSLLCCPFPLAL----GTSEPAHATAPEQGVWQLMLVTLVAYVLLPVR--TLLAVLFGIMLAASHFVVFATSFTGR---KQRMWRPLVANAVLFTSVNLSGVFVRILTERTQRKVFLQARNCIQERLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTIASVVEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKTTLECLNGDYEVE-------PGFGHERHSFLQKHHIETFFIVPSHRRK 475          

Query: 3039 IVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSD--VASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGT 3860
            +++ + F+  +   SR L+   RL + W  +    R +  K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GVL  SI ++    ++   +      +R+LN+++  FD++M+   Y  I KI+T G T   A+G+ P     +S  +  + ++L   ++    +    ++ N +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI VT +    I  +  + F   G + V   GQ+++       PG+
Sbjct:  778 VLAVLLFSGALALHSRQLDLKLRLDYLWATQAEEDRNDMEKVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVLFASIANFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKECYRDIEKIKTIGSTYMAAVGLVP---TTASKAKKSITSHLCTVSDFAIEMFNVLDAINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQVTEDVHRLI--TDFYNFVCRGQVSVKGKGQMLTYLLEGRRPGS 1050          

Query:  282 EGFTFLDEQRRKTTDFCPIICCSQLIDNYLSTDEWCNFFKCGSESINPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTN-VRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR-ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQ 1808
            E   F   Q+R+ T  CP       +D     DE                F +  LE ++  Y   + +++ L    +LI +    + ++E++ +     + G+N V C + +S+ I+T +  + +   Q +    + F  F+  +LCC   +++    G  +    +    G+W+ + + +      PV   TLLA+   + ++ S   +     + +     + W  L  N +LF    L G  +  L ++  R  FL AR  +   +  +  NEK +RLL  ++P  +  E+K+  +   E   H   +    NVS +  +I G +  A         + + VKL+NELF +FD L  E  C ++++  D Y  ++G  + + DHA  C E+   +  TI  + ++ EV L++R  +HTG     VLG  +  +D+  +DV +   M     PGKV ++K+T + L   Y+V+       P       S    + ++T+++ P H ++
Sbjct:    7 EEMPFARVQKRRRTGHCP---APAPLDAIACEDE----------------FNSHELEALFQSYNLKLEQTSTLKALAVLI-VAASSMTLMELLSSPRLTLSKGSNPVHCVVFLSLFIVTNVKYLQVTQLQQIAKLALLF-SFTFSLLCCPFPLAL----GTSEPAHATAPEQGVWQLMLVTLVAYVLLPVR--TLLAVLFGIMLAASHFVVFATSFTGR---KQRMWRPLVANAVLFTSVNLSGVFVRILTERTQRKVFLQARNCIQERLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTSLASQ-----CTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLTQPKADHAHCCVEMGLDMIDTIASVVEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAGGLPGKVHITKTTLECLNGDYEVE-------PGFGHERHSFLQKHHIETFFIVPSHRRK 475          

Query: 3039 IVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDV--ASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPE--NRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIH 3731
            +++ + F+  +   SR L+   RL + W  +    R +  K+ +   R++  LLP  V  H+L  +   M+L+   Y  +GVL  SI ++    ++   +      +R+LN+++  FD++M+   Y  I KI+T G T   A+G+    P  +S  +  + ++L   ++    +    ++ N +  N F+LR+GI++    +GV+G   P + +WG     A+ +   G   KI 
Sbjct:  778 VLAVLLFSGALALHSRQLDLKLRLDYLWATQAEEDRNDMEKVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVLFASIANFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKECYRDIEKIKTIGSTYMAAVGLV---PTTASKAKKSITSHLCTVSDFAIEMFNVLDAINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGKIQ 1009          

Query:  432 FKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQ-HMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLR--ELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLG 1709
            F++  LER+Y +YF   +R  Q +   +L+G+  +V GI+         P+   +    +S++MA+   + +V      C R   H  ++    + L   +LVSV  ++G   +   S  + G+W +++ I  I    PV    + A  +   +   I  +    ++++  F    W  +S N L+F+ + +IG    Y  +   R AF   R ++ + +  +  N++ +RLL  V+P  +  E+K  I  +  ++  H   +    NVS +  +I G +  A         + + V  +NELF+RFD L  E  C ++++  D Y  ++G PE R DHA  C E+   +   I  + +   V +++R  +H+G  +  VLG  +  FD+  +DV +   M      G++ ++K+T   L   Y+V+ G
Sbjct:  163 FQSRKLERLYQRYF---FRLNQ-SSLTMLMGVLVIVCGIMLTFHCVHAAPHVAYSSA--LSVAMALFMALMVV------CNRNGFHQDYMWMVSY-LVIGVLVSVQ-VFGVLMVAPRS-ASEGIWWSVFFIYIIYTLLPVR---MRAAVLSGAVLSIIHVVTTWQINQEDKFL---WKQVSANVLIFLCTNIIGICTHYPAEVSQRQAFQETRGYIQARLHLQRENQQQERLLLSVLPRHVAMEMKADINAKKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQ-----CTAQELVMTLNELFARFDKLASENHCLRIKILGDCYYCVSGLPEPRADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLQYLNGDYEVEPG 565          

Query: 2826 CPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGT-------VICTCVIIFGTHELI--------------FTEFSKT-----YRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLF--SCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGI-DPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNF 3746
            CP P Y  YS +   L   V L +    K+ ++L         V    V +F   +L               +T F++T     Y    V ++ ++ ++  +F   L L   ++ +T  RL F W+++   ++EE  +L     R++  +LPK V +H+L   R    L+  SCE   +   S+S  S   V ++  ++    +R+LN+++  FD+++    Y  + KI+T G T   A G+ D  +  E     + L    +R  E +K I  EH+  N    F ++IG+++    +GV+G   P + +WG     A+ +   G  D+I VT++ 
Sbjct:  843 CPFPEYFSYSVLLTLLACSVFLQISSIGKLTLMLLIQFTFLLLVEWPQVALFDNADLFVTSNAIDLNETVFQWTSFNETTNQCPYAVTKVSLRVMTPVILTVFVLALYLHAQQVEST-ARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASISNFSEFYVELEANNEGVECLRLLNEIIADFDEIISEEKYRQLEKIKTIGSTYMAASGLNDSTYDKEGRSHITALADYSMRLREQMKYI-NEHSFNN----FQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDL 1172          

Query:   90 MSYTAIPPQDRALKSSCNGYVKRSTLRAERGSCLKSPASLQRRTSGPAIPNSLRKTAPEHQEIYEGFTFLDEQRRKTTDFCPIICCSQLIDNYLSTDEWCNFFKCGSESINPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFXXXXXXXXXXXXXXXXKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYIXXXXXXXGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETITKIYKAYPLLTNLLDGNESGKYSQKINQNSFSQSQTHKSLDYSDTNEKGCEGHNXXXXXXXXXXXXTNQTITKTSAFSKLAQTAKFNANIPYYFXXXXXXXXXXXXXXXXXXXIGGAIVSSNIHNVTGSPVFHGTTKSSASWKSTLKSQFTQSLIGSYQIDEDDISLKKTSEIDLSISRVRNTFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTXXXXXXXXXXXXWIGXXXXXXXXXKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKXXXXXXXXXXXSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMIPNNLVPICSDESIISIGGRRNSLTVVMASGEPINHYMMNSTPVVPHNATASLMSSNPLVMPRNGAIPPGMSPXXXXXXXXXXGLFSITPITXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLGSSSNPQPIPQILPQKSIALAHNSNFMKSPQEPMNRKSILEARPKIHHYRNLATELPDTVIPPSPPPHRKIYPDTVNTGLVQSGLPVIVPQTDQFVHCQLEHQTPREKYLVRDTNQMTQSAISPPKERNTRSTKCITPSSSMDSFLELEKACTTNPRTKSANYSIPPNERLSLIPESYKLVPETDLIEDESYHNAEDIASVDIMTTSDDRIFDTDQADIMSHHNPMYTDNEYESMAESQANLLDPIEEIRRSRLISKKQIGSDYGSGIADKLLEHKLECIXXXXXXXXXXXXXXXVINGTSFDFPDYRRPASPSGGINGDDSDHLXXXXXXXXXXXXXXXIAAHRSGGATSSDESGKKESNNNCNKILEISQASFSNGNQISVTEDISNGEHGVLAIHCGIANRDSANKGYDNGSSCMSLVTDLGWTSYDDEDMYSDYPGYAGRYKLNGDQNNKNRKRSDWVSKWSDSNDLLSSNVQGXXXXXXXXCIRFHSDLISDVSENPLVSDLETETDCDFKSSDPAIGSMVNENRINSYYKFPVNNILNPEFYGNNQYKSDKPFDDQYSKGDINNRMFAAHPWIDSSHINKVRNENDIYSLATSSRGEDLXXXXXXXXXXXGQEQNRTTKLPDIAPVRMPDFGDSHMGFRMSRDVVKPTVASRFAKKHGRYISSSPERSDYDNVSGRNSLQDSGNHIPAAISSRNSDMGRYNYGDDSDALSGYVGDVASSVYDSDEYDEAPGKRFTQLYLNYDVDNEDXXXXXXXXXXXXXXXHRPSEPQLQKRSQNSSGSLNGKRSDYDNLDSDKLSDIYSRNDKKKKYLKTQPNIKSNEDYQQQIAEEARRISLVFQNQWTTEKKAPITIEPKLGNNKKSDCKHRIKSFFVNSQRETSVESELSSMNIHSNGILESNHIPYDKGAKSRSTDCLLTCTSTVSNDCCNDKLENELLKQKSLDDYNRGLSKIIQRAERVRSLLPTELHSYILPGCFXXXXXXXXXXXXPIRXXXXXXXXXXXXRHNERQYFSDEERSNQHQV 7373
            MSYTAIPPQDRALKSSCNGYVKRSTLRAERGSCLKSPASLQRRTSGPAIPNSLRKTAPEHQEIYEGFTFLDEQRRKTTDFCPIICCSQLIDNYLSTDEWCNFFKCGSESINPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFLCMSHSIISILLIVLSKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYISMSMSSSGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETITKIYKAYPLLTNLLDGNESGKYSQKINQNSFSQSQTHKSLDYSDTNEKGCEGHNSRSGQSDSLSSSTNQTITKTSAFSKLAQTAKFNANIPYYFLTDDSFLLSSPDDDRLLLDIGGAIVSSNIHNVTGSPVFHGTTKSSASWKSTLKSQFTQSLIGSYQIDEDDISLKKTSEIDLSISRVRN FLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTVMLLLMFLVVFMWIGLLLLLILLIKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKQQQQTLPQQQQSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMIPNNLVPICSDESIISIGGRRNSLTVVMASGEPINHYMMNSTPVVPHNATASLMSSNPLVMPRNGAIPPGMSPNAQNYNNNSNGLFSITPITSLSNLPSNINSNSPLPSNISSIIPAVNPPANNPSLGSSSNPQPIPQILPQKSIALAHNSNFMKSPQEPMNRKSILEARPKIHHYRNLATELPDTVIPPSPPPHRKIYPDTVNTGLVQSGLPVIVPQTDQFVHCQLEHQTPREKYLVRDTNQMTQSAISPPKERNTRSTKCITPSSSMDSFLELEKACTTNPRTKSANYSIPPNERLSLIPESYKLVPETDLIEDESYHNAEDIASVDIMTTSDDRIFDTDQADIMSHHNPMYTDNEYESMAESQANLLDPIEEIRRSRLISKKQIGSDYGSGIADKLLEHKLECINSRGNTNSSNSFGSNVINGTSFDFPDYRRPASPSGGINGDDSDHLSKRNRNSSNSRDSSSIAAHRSGGATSSDESGKKESNNNCNKILEISQASFSNGNQISVTEDISNGEHGVLAIHCGIANRDSANKGYDNGSSCMSLVTDLGWTSYDDEDMYSDYPGYAGRYKLNGDQNNKNRKRSDWVSKWSDSNDLLSSNVQGDDDDSDIDCIRFHSDLISDVSENPLVSDLETETDCDFKSSDPAIGSMVNENRINSYYKFPVNNILNPEFYGNNQYKSDKPFDDQYSKGDINNRMFAAHPWIDSSHINKVRNENDIYSLATSSRGEDLSSTSSKTPSKSGQEQNRTTKLPDIAPVRMPDFGDSHMGFRMSRDVVKPTVASRFAKKHGRYISSSPERSDYDNVSGRNSLQDSGNHIPA ISSRNSDMGRYNYGDDSDALSGYVGDVASSVYDSDEYDEAPGKRFTQLYLNYDVDNEDPMAPFFPRLPPPQDFHRPSEPQLQKRSQNSSGSLNGKRSDYDNLDSDKLSDIYSRNDKKKKYLKTQPNIKSNEDYQQQIAEEARRISLVFQNQWTTEKKAPITIEPKLGNNKKSDCKHRIKSFFVNSQRETSVESELSSMNIHSNGILESNHIPYDKGAKSRSTDCLLTCTSTVSNDCCNDKLENELLKQKSLDDYNRGLSKIIQRAERVRSLLPTELHSYILPGCFSSSSLNSSGKSSPIRKKLSKNVKSVNSRHNERQYFSDEERSNQHQV
Sbjct:    1 MSYTAIPPQDRALKSSCNGYVKRSTLRAERGSCLKSPASLQRRTSGPAIPNSLRKTAPEHQEIYEGFTFLDEQRRKTTDFCPIICCSQLIDNYLSTDEWCNFFKCGSESINPFAFKNINLERIYAKYFSLVYRSTQLARFFLLIGLFCLVIGIIEMIPTFLYPPNYGTNVRCWISISMAILTIIPLVHINCQQCMRPQHMAFLKFSGFILCCAILVSVSPIWGNFKIDSESFITVGLWETIWLIITISCFYPVTFYTLLALTIFLCMSHSIISILLIVLSKKPVFSSKHWAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDLPYISMSMSSSGDSNRMDTYYLRPKHIKQNSILATSDLIVSDTSDSQHDETITKIYKAYPLLTNLLDGNESGKYSQKINQNSFSQSQTHKSLDYSDTNEKGCEGHNSRSGQSDSLSSSTNQTITKTSAFSKLAQTAKFNANIPYYFLTDDSFLLSSPDDDRLLLDIGGAIVSSNIHNVTGSPVFHGTTKSSASWKSTLKSQFTQSLIGSYQIDEDDISLKKTSEIDLSISRVRNAFLDSTMESKFQNQSEKYMGFALLISLSTVLFITSLHALMLAKTVMLLLMFLVVFMWIGLLLLLILLIKMKFISGHIVRSHLCSVILLIITSLGIFTLIVSNSFCCINSPQLNATYKQQQQTLPQQQQSDSHLLCPLPVYIPYSTIWVTLPLIVMLALPETFKVVIVLGTVICTCVIIFGTHELIFTEFSKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYKTIGVLSVSIPSWCPVGVKEPSDVASNIRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKNPENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQLISVPPGQWVPGTITFRVFMLREKTLSHGSMIPNNLVPICSDESIISIGGRRNSLTVVMASGEPINHYMMNSTPVVPHNATASLMSSNPLVMPRNGAIPPGMSPNAQNYNNNSNGLFSITPITSLSNLPSNINSNSPLPSNISSIIPAVNPPANNPSLGSSSNPQPIPQILPQKSIALAHNSNFMKSPQEPMNRKSILEARPKIHHYRNLATELPDTVIPPSPPPHRKIYPDTVNTGLVQSGLPVIVPQTDQFVHCQLEHQTPREKYLVRDTNQMTQSAISPPKERNTRSTKCITPSSSMDSFLELEKACTTNPRTKSANYSIPPNERLSLIPESYKLVPETDLIEDESYHNAEDIASVDIMTTSDDRIFDTDQADIMSHHNPMYTDNEYESMAESQANLLDPIEEIRRSRLISKKQIGSDYGSGIADKLLEHKLECINSRGNTNSSNSFGSNVINGTSFDFPDYRRPASPSGGINGDDSDHLSKRNRNSSNSRDSSSIAAHRSGGATSSDESGKKESNNNCNKILEISQASFSNGNQISVTEDISNGEHGVLAIHCGIANRDSANKGYDNGSSCMSLVTDLGWTSYDDEDMYSDYPGYAGRYKLNGDQNNKNRKRSDWVSKWSDSNDLLSSNVQGDDDDSDIDCIRFHSDLISDVSENPLVSDLETETDCDFKSSDPAIGSMVNENRINSYYKFPVNNILNPEFYGNNQYKSDKPFDDQYSKGDINNRMFAAHPWIDSSHINKVRNENDIYSLATSSRGEDLSSTSSKTPSKSGQEQNRTTKLPDIAPVRMPDFGDSHMGFRMSRDVVKPTVASRFAKKHGRYISSSPERSDYDNVSGRNSLQDSGNHIPAVISSRNSDMGRYNYGDDSDALSGYVGDVASSVYDSDEYDEAPGKRFTQLYLNYDVDNEDPMAPFFPRLPPPQDFHRPSEPQLQKRSQNSSGSLNGKRSDYDNLDSDKLSDIYSRNDKKKKYLKTQPNIKSNEDYQQQIAEEARRISLVFQNQWTTEKKAPITIEPKLGNNKKSDCKHRIKSFFVNSQRETSVESELSSMNIHSNGILESNHIPYDKGAKSRSTDCLLTCTSTVSNDCCNDKLENELLKQKSLDDYNRGLSKIIQRAERVRSLLPTELHSYILPGCFSSSSLNSSGKSSPIRKKLSKNVKSVNSRHNERQYFSDEERSNQHQV 2428          

Query: 1218 LRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDL 1724
              NVS +  +I G +  +         +   V L+N+LF+RFD L     C ++    D Y  +AG P  R DHA SC E+   +   IKQ     +  +++R  VHTG    A++G  R  FD+  +DV I   M     PG+V +S+S Y+ +   Y V+ G  L++
Sbjct:  320 FENVSILFADIVGFTNMSSNKT-----APQVVTLLNDLFNRFDELCNITNCEKLGTLGDCYYCVAGCPLPRPDHAVSCIEMGLGMCRIIKQFNHDHKENVNMRVGVHTGRVNAAIIGKQRFRFDVYSNDVIIANTMESSGKPGQVHISQSVYELIRHAYNVEPGDDLEI 483          

Query: 2991 SKTYRSDGVPIKYISAIVSQIFFAILVLWKSRILNTFRRLVFQWQMKMNLKREEHHKLIVTVDRMIDILLPKFVVSHYLNPSRNYMNLFSCEYK----TIGVLSVSIPSWCPVGVKEPSDVASN-IRVLNQLLITFDDVMESSDYEGITKIRTAGETAWYAIGIDPDHPIESSVDRSRLMTNLLRGAEMLKRIVQEHNSKN--PENRFLLRIGIHMAAGFSGVVGGNNPTFGVWGEAYFGATIVQRCGQLDKIHVTSNFMAEIDPSSKFGFYDVGTLIVNHAGQL 3824
            SK + +D +  +Y    +   F  ++ L + R  N   R+ F    +  + REE  + + +   ++  ++PK+V  +        +   +  Y       GV+   I ++     +E      N +++L+ ++  FD ++ + +Y+ + KI+T  +    A G++    IE + ++   +  L+  A  +++I+   N       ++F ++IG +     +G++G   P + +WG+    ++ +   G+  +I V      E+ P   F F   G + V   G +
Sbjct:  809 SKKFYNDILLREYFYQYLFS-FIIMIALIRERERNL--RIWFYVSREAEIGREEALRAMQSSQELLYNIIPKYVFDYVRLRGGENLECANFNYALAVPRAGVVFACISNFFSKYYREDYKGGGNALKLLHNIICKFDQILMNKEYKDVEKIKTINDCYMLASGLNAS-EIEFNENKHEHLIALMNYAFHMQKILGNFNEYYIIGSDKFEIKIGYNFGPVTAGIIGSTKPMYDIWGDTVNVSSRMYSTGKHSEIQVPHYVAEELKPY--FLFKYRGIIFVKGKGDM 1087          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLL-------SCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRL 1718
            +  L G  +LF    L G  +        ++AFL          +N  A  K+D  +         ++P  +  E  +SI  ++L  +L      +NVS +  +I G +  +         +   V L+N+L++RFD  G+ + C ++    D Y  ++G P  R DHA  C E+   +   I       +  +++R  VH+G    A++GN R  FD+  +DV I   +     PGKV +SK T+  +   Y    G +L
Sbjct:  192 YYMLIGQIILFFMVYLTGLYLRIFNSIRRKSAFL-------KLAQNAQAKMKMDSAIKVQIYWIEAIMPAAVRGEFLESIRSKDLF-NLGYCKQFKNVSILFADIVGFTAMSSNKT-----AKQLVYLLNDLYNRFDDFGKIMNCEKIATLGDCYYCVSGCPVPRSDHALCCVEMGLGMCKMILAFNRLHKEEVNMRVGVHSGRVIAAIIGNLRFRFDVYSNDVSIANALESSGKPGKVHISKKTFKLVCHAYTFIEGEKL 439          

Query: 1143 MPILAELKQSIMLRELHGHLPSVVHLRN---VSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRLDL 1724
            MP  + +K+  + R     + S+V+ +N   VS +  +I G ++ +         ++  V L+N+L++RFD+ G++  C ++    D Y  ++G P  R+DHA +C E+   +   I +     +  +++R  +H+G    A++GN R  FD+  +DV I   +     PG V +S+ TY  +   Y V+ G  L++
Sbjct:  251 MP--SSVKEQFLKRIRDNDMFSLVYCQNFDNVSILFADIVGFTKMSANKT-----AAKLVYLLNDLYNRFDVQGRQTNCEKIGTLGDCYYCVSGCPIPRIDHAINCVEMGLGMCRIIMKFNKDHKEKVNMRVGIHSGRVIAAIIGNHRFRFDVFSNDVVIANSLESSGKPGLVHISEDTYVLVRHAYAVNEGEALEI 440          

Query:  957 WAALSGNWLLFIPSILIGSVISYLQQKMLRNAFLYAREFLNSCVENKMANEKLDRLLSCVVPMPILAELKQSIMLRELHGHLPSVVHLRNVSFINVEICGLSRGARGDGNGISFSSDAVKLMNELFSRFDMLGQELGCYQVRVHPDDYLSLAGYPETRVDHAKSCTELAFRIQHTIKQLCDSAEVMLDVRTVVHTGVTYGAVLGNSRMVFDLLGDDVRILRFMLGIAAPGKVMVSKSTYDQLPEGYKVDLGPRL 1718
            +  L    LLF    L+G  + +      ++AFL   +   + ++ + A E     +  ++P  +  E  Q++  ++   +L      ++VS +  +I G +  +         +   V L+N+L++RFD  G  + C ++    D Y  ++G P  R DHA  C E+   +   I       +  +++R  VH+G    A++GN R  FD+  +DV I   +     PGKV +S+ T+  +   Y    G +L
Sbjct:  168 YNLLVAECLLFFAVYLVGLYLRFFNSIRRKSAFLKLAQNAQAKMKMESAIEVQIYWIEAIMPSAVKTEFLQNVRHKDFF-NLVYCRQFKDVSILFADIVGFTAMSSNKT-----AKQLVYLLNDLYNRFDDFGNIMNCEKIATLGDCYYCVSGCPVPRSDHALCCVEMGLGMCKMIMTFNKVHKEEVNMRVGVHSGRVIAAIIGNLRFRFDVYSNDVSIANALESSGKPGKVHISEKTFKLVCHAYTFVEGEKL 415