cGMP-dependent protein kinase,putative

Overview
NamecGMP-dependent protein kinase,putative
Smed IDSMED30025573
Length (bp)2312
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cGMP-dependent protein kinase,putative (SMED30025573) t-SNE clustered cells

Violin plots show distribution of expression levels for cGMP-dependent protein kinase,putative (SMED30025573) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cGMP-dependent protein kinase,putative (SMED30025573) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cGMP-dependent protein kinase,putative (SMED30025573) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30025573

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30025573h1SMcG0003250 dd_Smed_v4_10515_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30025573h1SMcG0003250 dd_Smed_v6_10515_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Match: PRKG1 (protein kinase cGMP-dependent 1 [Source:HGNC Symbol;Acc:HGNC:9414])

HSP 1 Score: 746.503 bits (1926), Expect = 0.000e+0
Identity = 383/670 (57.16%), Postives = 490/670 (73.13%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Match: PRKG1 (protein kinase cGMP-dependent 1 [Source:HGNC Symbol;Acc:HGNC:9414])

HSP 1 Score: 730.709 bits (1885), Expect = 0.000e+0
Identity = 378/679 (55.67%), Postives = 489/679 (72.02%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQKKEVRGIGISAEPRGLN--FNYDSLA---KGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I +L+ +L  ++++  P   Q ++     +  EPR      + +  A   + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQAQKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 686
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Match: PRKG2 (protein kinase cGMP-dependent 2 [Source:HGNC Symbol;Acc:HGNC:9416])

HSP 1 Score: 627.476 bits (1617), Expect = 0.000e+0
Identity = 345/722 (47.78%), Postives = 478/722 (66.20%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKN----------IPVKLQKKEV--------RGI--GISAEPRGLNFNYD-----SLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKL-RQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRD-----------LVNFNRDYEDEKLSDKQRSIFNY----------LQLKD-------------LCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L E + +L+K+ + I  L E +Q K  Q+ +L+ D+ + +           +P+++ +K          RG   G+SAEP    ++ +     S  K    V K+   K+ +  A+ +N F++ L   QI D+VE MY       S+II++GE G+ ++ L +G +E+  +GEKL   +   + FGELAILYNCTRTASV+A T  K W +DRE FQ+IM ++   R E+Y  FL+SV   K L  +KL KI D L   +Y+K DYIIREG  G TF+I++KGKVKVT+    +++ +  I+ L +G++FGEKAL  +DVR+ANIIA ++D V CLV+DR+++N  +             + N NRD  DEK   K RS+ N+          +QLK+             L  +AT+G+GGFGRVELV++ N+ + +FA+K ++K HIV+T+QQEHV +EKRILEE+ S FIVKLY+TFKD KY+YM++E CLGGE+W+ILRDR  FD+ T++F  ACV  A DYLHR GI+YRDLKPENLILD++GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPE+ILNKGHDFS DFWSLGIL++ELLTG PPFS  D M TYN+ILKGIE ++ P  +++   +LI++L R NP ERLG  K GI +++KH W  GFNW GL  R++  P+  ++K  IDHS FD YPP++ +PPD++SGWD +F
Sbjct:   51 LKELREQLSKQTVAIAELTEELQNKCIQLNKLQ-DVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKA--RVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEV-FQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQ-LIKTLQKGEYFGEKALISDDVRSANIIAEEND-VACLVIDRETFNQTVGTFEELQKYLEGYVANLNRD--DEKRHAK-RSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF 762
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Match: PRKG2 (protein kinase cGMP-dependent 2 [Source:HGNC Symbol;Acc:HGNC:9416])

HSP 1 Score: 627.476 bits (1617), Expect = 0.000e+0
Identity = 345/722 (47.78%), Postives = 478/722 (66.20%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKN----------IPVKLQKKEV--------RGI--GISAEPRGLNFNYD-----SLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKL-RQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRD-----------LVNFNRDYEDEKLSDKQRSIFNY----------LQLKD-------------LCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L E + +L+K+ + I  L E +Q K  Q+ +L+ D+ + +           +P+++ +K          RG   G+SAEP    ++ +     S  K    V K+   K+ +  A+ +N F++ L   QI D+VE MY       S+II++GE G+ ++ L +G +E+  +GEKL   +   + FGELAILYNCTRTASV+A T  K W +DRE FQ+IM ++   R E+Y  FL+SV   K L  +KL KI D L   +Y+K DYIIREG  G TF+I++KGKVKVT+    +++ +  I+ L +G++FGEKAL  +DVR+ANIIA ++D V CLV+DR+++N  +             + N NRD  DEK   K RS+ N+          +QLK+             L  +AT+G+GGFGRVELV++ N+ + +FA+K ++K HIV+T+QQEHV +EKRILEE+ S FIVKLY+TFKD KY+YM++E CLGGE+W+ILRDR  FD+ T++F  ACV  A DYLHR GI+YRDLKPENLILD++GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPE+ILNKGHDFS DFWSLGIL++ELLTG PPFS  D M TYN+ILKGIE ++ P  +++   +LI++L R NP ERLG  K GI +++KH W  GFNW GL  R++  P+  ++K  IDHS FD YPP++ +PPD++SGWD +F
Sbjct:   51 LKELREQLSKQTVAIAELTEELQNKCIQLNKLQ-DVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKA--RVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEV-FQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQ-LIKTLQKGEYFGEKALISDDVRSANIIAEEND-VACLVIDRETFNQTVGTFEELQKYLEGYVANLNRD--DEKRHAK-RSMSNWKLSKALSLEMIQLKEKVARFSSSSPFQNLEIIATLGVGGFGRVELVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF 762
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Match: PRKG2 (protein kinase cGMP-dependent 2 [Source:HGNC Symbol;Acc:HGNC:9416])

HSP 1 Score: 602.053 bits (1551), Expect = 0.000e+0
Identity = 333/699 (47.64%), Postives = 464/699 (66.38%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKN----------IPVKLQKKEV--------RGI--GISAEPRGLNFNYD-----SLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKL-RQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRD-----------LVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L E + +L+K+ + I  L E +Q K  Q+ +L+ D+ + +           +P+++ +K          RG   G+SAEP    ++ +     S  K    V K+   K+ +  A+ +N F++ L   QI D+VE MY       S+II++GE G+ ++ L +G +E+  +GEKL   +   + FGELAILYNCTRTASV+A T  K W +DRE FQ+IM ++   R E+Y  FL+SV   K L  +KL KI D L   +Y+K DYIIREG  G TF+I++KGKVKVT+    +++ +  I+ L +G++FGEKAL  +DVR+ANIIA ++D V CLV+DR+++N  +             + N NRD  DEK   K RS+ N+ +L     +  I +      E V++ N+ + +FA+K ++K HIV+T+QQEHV +EKRILEE+ S FIVKLY+TFKD KY+YM++E CLGGE+W+ILRDR  FD+ T++F  ACV  A DYLHR GI+YRDLKPENLILD++GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPE+ILNKGHDFS DFWSLGIL++ELLTG PPFS  D M TYN+ILKGIE ++ P  +++   +LI++L R NP ERLG  K GI +++KH W  GFNW GL  R++  P+  ++K  IDHS FD YPP++ +PPD++SGWD +F
Sbjct:   51 LKELREQLSKQTVAIAELTEELQNKCIQLNKLQ-DVVHMQGGSPLQASPDKVPLEVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKA--RVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEV-FQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQ-LIKTLQKGEYFGEKALISDDVRSANIIAEEND-VACLVIDRETFNQTVGTFEELQKYLEGYVANLNRD--DEKRHAK-RSMSNW-KLSKALSLEMIQLK-----EKVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYFDKYPPEKGMPPDELSGWDKDF 733
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 319/647 (49.30%), Postives = 446/647 (68.93%), Query Frame = 3 
Query:  324 ELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDE--------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVP-VTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L  DL+    +P    ++  + I +SAEP     N+++    L H  K    K+ +  A+ +NDF++ L+  QI +LV  MY +   +  W+IQEGE G  ++ + +G ++++ +G  L +M  G++ GELAILYNCTRTASV+A T  +LW +DR  FQ I  + G+ R  + + FL  V  F+ L  +++ K+ADV+ +++Y+   YIIR+G +GD F++I+ G+VKVT++     E    IR L++G +FGE+AL  E+VRTANIIA    GV+ L LDR+S+  LI DL +  +DY D+              K+ D  R  F  + LK++  +AT+G+GGFGRVELV +  D++++FALK LKK HIV+TRQQEH+  E+ I+ E  +++IVKLYKTF+D+K++YM++EVCLGGE+WT LRDR  FDD TARFY ACV+  L+YLHRK IVYRDLKPEN +L + GY K+ DFGF+KK+   RKTWTFCGTPEYV+PEIILNKGHD +AD+W+LGI + EL+ G PPF  SDPMKTY +ILKG++A+E+P   + K A  L+KKL RDNP ERLG G  G+ +++KH WF GF+W GL  R ++PPI+PKV +  D +NFD+YPPD DVPPD+ SGWD  F
Sbjct:  110 QLGNDLQQKAVLPADGVQR-AKKIAVSAEPT----NFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPRE-IRVLNQGDFFGERALLGEEVRTANIIA-QAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF 749
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 319/647 (49.30%), Postives = 446/647 (68.93%), Query Frame = 3 
Query:  324 ELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDE--------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVP-VTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L  DL+    +P    ++  + I +SAEP     N+++    L H  K    K+ +  A+ +NDF++ L+  QI +LV  MY +   +  W+IQEGE G  ++ + +G ++++ +G  L +M  G++ GELAILYNCTRTASV+A T  +LW +DR  FQ I  + G+ R  + + FL  V  F+ L  +++ K+ADV+ +++Y+   YIIR+G +GD F++I+ G+VKVT++     E    IR L++G +FGE+AL  E+VRTANIIA    GV+ L LDR+S+  LI DL +  +DY D+              K+ D  R  F  + LK++  +AT+G+GGFGRVELV +  D++++FALK LKK HIV+TRQQEH+  E+ I+ E  +++IVKLYKTF+D+K++YM++EVCLGGE+WT LRDR  FDD TARFY ACV+  L+YLHRK IVYRDLKPEN +L + GY K+ DFGF+KK+   RKTWTFCGTPEYV+PEIILNKGHD +AD+W+LGI + EL+ G PPF  SDPMKTY +ILKG++A+E+P   + K A  L+KKL RDNP ERLG G  G+ +++KH WF GF+W GL  R ++PPI+PKV +  D +NFD+YPPD DVPPD+ SGWD  F
Sbjct:  110 QLGNDLQQKAVLPADGVQR-AKKIAVSAEPT----NFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPRE-IRVLNQGDFFGERALLGEEVRTANIIA-QAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF 749
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360])

HSP 1 Score: 644.81 bits (1662), Expect = 0.000e+0
Identity = 319/647 (49.30%), Postives = 446/647 (68.93%), Query Frame = 3 
Query:  324 ELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDE--------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVP-VTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L  DL+    +P    ++  + I +SAEP     N+++    L H  K    K+ +  A+ +NDF++ L+  QI +LV  MY +   +  W+IQEGE G  ++ + +G ++++ +G  L +M  G++ GELAILYNCTRTASV+A T  +LW +DR  FQ I  + G+ R  + + FL  V  F+ L  +++ K+ADV+ +++Y+   YIIR+G +GD F++I+ G+VKVT++     E    IR L++G +FGE+AL  E+VRTANIIA    GV+ L LDR+S+  LI DL +  +DY D+              K+ D  R  F  + LK++  +AT+G+GGFGRVELV +  D++++FALK LKK HIV+TRQQEH+  E+ I+ E  +++IVKLYKTF+D+K++YM++EVCLGGE+WT LRDR  FDD TARFY ACV+  L+YLHRK IVYRDLKPEN +L + GY K+ DFGF+KK+   RKTWTFCGTPEYV+PEIILNKGHD +AD+W+LGI + EL+ G PPF  SDPMKTY +ILKG++A+E+P   + K A  L+KKL RDNP ERLG G  G+ +++KH WF GF+W GL  R ++PPI+PKV +  D +NFD+YPPD DVPPD+ SGWD  F
Sbjct:  110 QLGNDLQQKAVLPADGVQR-AKKIAVSAEPT----NFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPRE-IRVLNQGDFFGERALLGEEVRTANIIA-QAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF 749
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360])

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 319/647 (49.30%), Postives = 446/647 (68.93%), Query Frame = 3 
Query:  324 ELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDE--------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVP-VTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L  DL+    +P    ++  + I +SAEP     N+++    L H  K    K+ +  A+ +NDF++ L+  QI +LV  MY +   +  W+IQEGE G  ++ + +G ++++ +G  L +M  G++ GELAILYNCTRTASV+A T  +LW +DR  FQ I  + G+ R  + + FL  V  F+ L  +++ K+ADV+ +++Y+   YIIR+G +GD F++I+ G+VKVT++     E    IR L++G +FGE+AL  E+VRTANIIA    GV+ L LDR+S+  LI DL +  +DY D+              K+ D  R  F  + LK++  +AT+G+GGFGRVELV +  D++++FALK LKK HIV+TRQQEH+  E+ I+ E  +++IVKLYKTF+D+K++YM++EVCLGGE+WT LRDR  FDD TARFY ACV+  L+YLHRK IVYRDLKPEN +L + GY K+ DFGF+KK+   RKTWTFCGTPEYV+PEIILNKGHD +AD+W+LGI + EL+ G PPF  SDPMKTY +ILKG++A+E+P   + K A  L+KKL RDNP ERLG G  G+ +++KH WF GF+W GL  R ++PPI+PKV +  D +NFD+YPPD DVPPD+ SGWD  F
Sbjct:   98 QLGNDLQQKAVLPADGVQR-AKKIAVSAEPT----NFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPRE-IRVLNQGDFFGERALLGEEVRTANIIA-QAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF 737
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Match: egl-4 (cGMP-dependent protein kinase egl-4 [Source:UniProtKB/Swiss-Prot;Acc:O76360])

HSP 1 Score: 644.425 bits (1661), Expect = 0.000e+0
Identity = 319/647 (49.30%), Postives = 446/647 (68.93%), Query Frame = 3 
Query:  324 ELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDE--------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVP-VTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L  DL+    +P    ++  + I +SAEP     N+++    L H  K    K+ +  A+ +NDF++ L+  QI +LV  MY +   +  W+IQEGE G  ++ + +G ++++ +G  L +M  G++ GELAILYNCTRTASV+A T  +LW +DR  FQ I  + G+ R  + + FL  V  F+ L  +++ K+ADV+ +++Y+   YIIR+G +GD F++I+ G+VKVT++     E    IR L++G +FGE+AL  E+VRTANIIA    GV+ L LDR+S+  LI DL +  +DY D+              K+ D  R  F  + LK++  +AT+G+GGFGRVELV +  D++++FALK LKK HIV+TRQQEH+  E+ I+ E  +++IVKLYKTF+D+K++YM++EVCLGGE+WT LRDR  FDD TARFY ACV+  L+YLHRK IVYRDLKPEN +L + GY K+ DFGF+KK+   RKTWTFCGTPEYV+PEIILNKGHD +AD+W+LGI + EL+ G PPF  SDPMKTY +ILKG++A+E+P   + K A  L+KKL RDNP ERLG G  G+ +++KH WF GF+W GL  R ++PPI+PKV +  D +NFD+YPPD DVPPD+ SGWD  F
Sbjct:   98 QLGNDLQQKAVLPADGVQR-AKKIAVSAEPT----NFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPRE-IRVLNQGDFFGERALLGEEVRTANIIA-QAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF 737
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Match: for (gene:FBgn0000721 transcript:FBtr0089310)

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 372/707 (52.62%), Postives = 496/707 (70.16%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PVKLQK-------------------------------------KEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            + F   +  KE++I+ +   +Q K+ +IAEL+  L  F+++ P                                          +  R +GISAEP+    +  SL   L HV+     K+++++E +  AIL+NDFM++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:  389 ERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQ----SESSLL--LEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Match: for (gene:FBgn0000721 transcript:FBtr0089312)

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 372/707 (52.62%), Postives = 496/707 (70.16%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PVKLQK-------------------------------------KEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            + F   +  KE++I+ +   +Q K+ +IAEL+  L  F+++ P                                          +  R +GISAEP+    +  SL   L HV+     K+++++E +  AIL+NDFM++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:  389 ERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQ----SESSLL--LEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Match: for (gene:FBgn0000721 transcript:FBtr0089304)

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 372/707 (52.62%), Postives = 496/707 (70.16%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PVKLQK-------------------------------------KEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            + F   +  KE++I+ +   +Q K+ +IAEL+  L  F+++ P                                          +  R +GISAEP+    +  SL   L HV+     K+++++E +  AIL+NDFM++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:  389 ERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQ----SESSLL--LEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Match: for (gene:FBgn0000721 transcript:FBtr0446099)

HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0
Identity = 372/707 (52.62%), Postives = 496/707 (70.16%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PVKLQK-------------------------------------KEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            + F   +  KE++I+ +   +Q K+ +IAEL+  L  F+++ P                                          +  R +GISAEP+    +  SL   L HV+     K+++++E +  AIL+NDFM++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:   43 ERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQ----SESSLL--LEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 742
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Match: for (gene:FBgn0000721 transcript:FBtr0473363)

HSP 1 Score: 684.485 bits (1765), Expect = 0.000e+0
Identity = 339/569 (59.58%), Postives = 438/569 (76.98%), Query Frame = 3 
Query:  522 MRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            M++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:    1 MKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 568
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Match: prkg1b (protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:ZDB-GENE-080225-40])

HSP 1 Score: 757.673 bits (1955), Expect = 0.000e+0
Identity = 383/667 (57.42%), Postives = 491/667 (73.61%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDL-KYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDK---QRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            +EF   L  KE  IK +   +  K +++ EL++ L KY   +P  +  +  R  GISAEP+      D  ++ L    K  ++KE +  AIL+NDFM++L  +QI ++V+ MYPV     S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ LQ E L K+ADVL E HY+  +YIIR+GARGDTF+IISKGKV VT++   N     ++R L +G WFGEKAL+ ED+RTAN+IA +   V CLV+DR+S+  LI  L +  N+ Y+D     K   + + F+ L+L D   + T+G+GGFGRVELVQ+ ++ +++FA+K LKK HIV+TRQQEH+ +EK+I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:    6 EEFAKMLLIKEERIKEMERLLSAKEQEVNELKRKLHKYQSVLPSTIGPRTRRAQGISAEPQTARSFQDLKSEALRKHHKSVRSKELIKEAILDNDFMKNLELSQIQEIVDCMYPVEYDKESCIIKEGDVGSLVYVMEDGKVEVTKEGMKLCTMGPGKVFGELAILYNCTRTATVQTLTNVKLWAIDRQCFQTIMMRTGLIKHAEYMEFLKSVPTFQGLQEEILSKLADVLEETHYSDGEYIIRQGARGDTFFIISKGKVNVTREDAPNG-TPVYLRALGKGDWFGEKALQGEDIRTANVIAAE--AVTCLVIDRESFKHLIGGLDDVSNKGYDDAGAKAKYEAENAFFSNLKLVDFNIIDTLGVGGFGRVELVQLKSEETKTFAMKILKKRHIVDTRQQEHIRSEKQIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLIPPIIPDVASPTDTSNFDSFPEDNEDPPPDDNSGWDTDF 669
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Match: prkg1b (protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:ZDB-GENE-080225-40])

HSP 1 Score: 737.643 bits (1903), Expect = 0.000e+0
Identity = 380/683 (55.64%), Postives = 492/683 (72.04%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQ---------KKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDK---QRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I +L+ +L  ++++  P   Q          +  +   ISAEP   +       + L+HV      K  ++KE +  AIL+NDFM++L  +QI ++V+ MYPV     S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ LQ E L K+ADVL E HY+  +YIIR+GARGDTF+IISKGKV VT++   N     ++R L +G WFGEKAL+ ED+RTAN+IA +   V CLV+DR+S+  LI  L +  N+ Y+D     K   + + F+ L+L D   + T+G+GGFGRVELVQ+ ++ +++FA+K LKK HIV+TRQQEH+ +EK+I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQVHKQSALQEHQRTKRQAISAEPTAFDI------QDLSHVTLPFYPKSPQSKELIKEAILDNDFMKNLELSQIQEIVDCMYPVEYDKESCIIKEGDVGSLVYVMEDGKVEVTKEGMKLCTMGPGKVFGELAILYNCTRTATVQTLTNVKLWAIDRQCFQTIMMRTGLIKHAEYMEFLKSVPTFQGLQEEILSKLADVLEETHYSDGEYIIRQGARGDTFFIISKGKVNVTREDAPNG-TPVYLRALGKGDWFGEKALQGEDIRTANVIAAE--AVTCLVIDRESFKHLIGGLDDVSNKGYDDAGAKAKYEAENAFFSNLKLVDFNIIDTLGVGGFGRVELVQLKSEETKTFAMKILKKRHIVDTRQQEHIRSEKQIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLIPPIIPDVASPTDTSNFDSFPEDNEDPPPDDNSGWDTDF 684
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Match: prkg1a (protein kinase cGMP-dependent 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1308])

HSP 1 Score: 737.643 bits (1903), Expect = 0.000e+0
Identity = 381/670 (56.87%), Postives = 488/670 (72.84%), Query Frame = 3 
Query:  234 LDE-FKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDK---QRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            LDE F   L  KE  I+ L   +  + ++I+EL++ L   +++    ++  +  R  GISAEP+    + D   +    VAK  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    NS II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+VR  +  KLW IDR+ FQ+IMM++G+ +  EY++ L+SV TF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV +T++     E   ++R + RG  FGEKAL+ ED+RTAN+IA +   V CLV+DRDSY  LI  L +  N+  ED +   K   + + F+ L L D   + T+G+GGFGRVELVQ+ +D  ++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  FDD T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RD P ERLG  K G+ ++QKH WFEGFNW+GL    + PPIIP V S+ D SNFDS+P D ED PPDD SGWD +F
Sbjct:    4 LDEDFAKILMLKEERIRDLERRLLEREDEISELKRKLHKCQSVLPSAQIGPRTHRAQGISAEPQT---HQDLSNQSFRRVAKSDRSKDLIKSAILDNDFMKNLEMSQIQEIVDCMYPVDYDKNSCIIKEGDVGSLVYVMEDGKVEVTKEGLKLCTMGPGKVFGELAILYNCTRTATVRTVSSVKLWAIDRQCFQTIMMRTGLIKHAEYMELLKSVLTFRGLPEEILSKLADVLEETHYEDGNYIIRQGARGDTFFIISKGKVTMTREDCPGQE-PVYLRSMGRGDSFGEKALQGEDIRTANVIAAET--VTCLVIDRDSYKHLIGGLEDVSNKGCEDAEAKAKYEAENAFFSNLNLSDFNIIDTLGVGGFGRVELVQLKSDEMKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGNFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDTPSERLGNLKNGVKDIQKHKWFEGFNWDGLRKGTLMPPIIPNVTSSTDTSNFDSFPEDNEDPPPDDNSGWDIDF 667
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Match: prkg1b (protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:ZDB-GENE-080225-40])

HSP 1 Score: 697.582 bits (1799), Expect = 0.000e+0
Identity = 362/667 (54.27%), Postives = 464/667 (69.57%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDL-KYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDK---QRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            +EF   L  KE  IK +   +  K +++ EL++ L KY   +P  +  +  R  GISAEP+      D  ++ L    K  ++KE +  AIL+NDFM++L  +QI ++V+ MYPV     S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+S  + +              + S PT                 + HY+  +YIIR+GARGDTF+IISKGKV VT++   N     ++R L +G WFGEKAL+ ED+RTAN+IA +   V CLV+DR+S+  LI  L +  N+ Y+D     K   + + F+ L+L D   + T+G+GGFGRVELVQ+ ++ +++FA+K LKK HIV+TRQQEH+ +EK+I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:    6 EEFAKMLLIKEERIKEMERLLSAKEQEVNELKRKLHKYQSVLPSTIGPRTRRAQGISAEPQTARSFQDLKSEALRKHHKSVRSKELIKEAILDNDFMKNLELSQIQEIVDCMYPVEYDKESCIIKEGDVGSLVYVMEDGKVEVTKEGMKLCTMGPGKVFGELAILYNCTRTATVQTLTNVKLWAIDRQSLTAFIS-------------IHSSPT----------------PDTHYSDGEYIIRQGARGDTFFIISKGKVNVTREDAPNG-TPVYLRALGKGDWFGEKALQGEDIRTANVIAAE--AVTCLVIDRESFKHLIGGLDDVSNKGYDDAGAKAKYEAENAFFSNLKLVDFNIIDTLGVGGFGRVELVQLKSEETKTFAMKILKKRHIVDTRQQEHIRSEKQIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLIPPIIPDVASPTDTSNFDSFPEDNEDPPPDDNSGWDTDF 640
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Match: prkg2 (protein kinase cGMP-dependent 2 [Source:ZFIN;Acc:ZDB-GENE-060531-80])

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 312/715 (43.64%), Postives = 450/715 (62.94%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKY---FKNIPVKLQKKEVRGI----------------GISAEPRGLNFNYDSLAK---GLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDYEDE----------------------------KLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +   + +LA+++  +  + +T++ K  Q+ +L+  LK       +P  L++K  +G+                G+SAEP    ++   + K       V KE+  K+ L  A+ +N ++R L   Q+ D+VE MY  T     ++I++GE G+ ++ L DG +++    + L  +   + FGELAILYNCTRTASV+A +  K W +DRE F +IM  +   R E+Y  FL+SV     L  +KL KI D L   +YNK DYIIREG  G+TFYII+        +  +++E    I  L +G +FGEKAL  +DVR+ANIIA + DGV+CLV+DR++++  +    +L  + + Y D                             +L +++ S  + +    L  +AT+G+GGFGRVELV++ N+ + +FALK +KK HIV+ RQ+EH+ +E+RIL E +  FIVK+Y+T+KD KY+YM++E CLGGE+W++LRDR  F++ TA+F   CV  A DYLH  GI+YRDLKPENL+LD+ GY K+ DFGF+KK+   ++TWTFCGTPEYVAPEIILNKGH  S DFWSLGIL+FELLTG+PPF+ SD M  Y  ILKGIE ++ P  ++K   +LI+KL R NP ERLG  K GI +++KH WF GF+W+GL  R +  P+  +VK   DHS FDSYPP+E++PPD++SGWD +F
Sbjct:   58 IKHLEEQLAQQKQTLSEISDTLRSKCLQLNKLQDALKSQGELGLLPSPLKEKVSQGLTGLLRETLNRRKGAKAGVSAEPSSRTYDSSGIPKFYFESARVWKEQSVKKLLTDALNKNQYLRRLEVQQVKDMVECMYERTYQQGEYVIKQGEPGNHLFVLADGKLDVYQHNKLLTSIAVWTTFGELAILYNCTRTASVKAASNVKTWALDREVFHNIMRMTAEARHEQYRNFLRSVSLLASLPGDKLTKIVDCLEVEYYNKGDYIIREGEEGNTFYIIA-NGKIKVTQSTQDHEEPQIINTLGKGDYFGEKALISDDVRSANIIA-EEDGVECLVIDRETFSQTVGTFDELKKYLQSYVDSLARDDKKRNAKRSGSCTPPNTPVSHDMIELKERESSFASTIPFTCLEAIATLGVGGFGRVELVKLKNE-NVTFALKCIKKRHIVDNRQEEHIYSERRILLETNCPFIVKMYRTYKDNKYVYMLLEACLGGEIWSLLRDRGSFEEYTAKFCVGCVTEAFDYLHNNGIIYRDLKPENLMLDTDGYVKLVDFGFAKKLKCGQRTWTFCGTPEYVAPEIILNKGHGLSVDFWSLGILIFELLTGSPPFTGSDQMIIYTFILKGIEKMDFPKKITKRPGDLIRKLCRQNPSERLGNLKNGITDIKKHRWFTGFSWSGLKARNLISPLKREVKGPTDHSYFDSYPPEEEIPPDEMSGWDTDF 769
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Match: camk4 (calcium/calmodulin-dependent protein kinase IV [Source:Xenbase;Acc:XB-GENE-5911781])

HSP 1 Score: 751.895 bits (1940), Expect = 0.000e+0
Identity = 382/671 (56.93%), Postives = 487/671 (72.58%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-----PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            ++F   L  KE  I+ L   +  K ++I EL++ L  ++++        +  +  R  GISAEP+     +D   +      K +++KE +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E + K+ADVL E HY   DYIIR+GARGDTF+IISKGKV VT++     E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ +D  ++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  FDD T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:    6 EDFARILMLKEERIRDLENRLSEKEKEIQELKRKLHKYQSVLAMPSTSHIGPRTTRAQGISAEPQSFRSYHDLTRQAFKKFTKSERSKELIKEAILDNDFMKNLEISQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKESVKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEIVSKLADVLEETHYESGDYIIRQGARGDTFFIISKGKVNVTREDSPG-EDPIFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFGNLKLADFNIIDTLGVGGFGRVELVQLKSDECKTFAMKILKKRHIVDTRQQEHIRSEKQIMQSAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNEDPPPDDNSGWDIDF 673
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Match: camk4 (calcium/calmodulin-dependent protein kinase IV [Source:Xenbase;Acc:XB-GENE-5911781])

HSP 1 Score: 739.569 bits (1908), Expect = 0.000e+0
Identity = 383/684 (55.99%), Postives = 489/684 (71.49%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI------------PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I  L+ +L  ++++            P  L ++  +   ISAEP  ++       + L+HV      K  ++KE +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E + K+ADVL E HY   DYIIR+GARGDTF+IISKGKV VT++     E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ +D  ++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  FDD T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQRLQNELDKYRSVIKPATQQVHKQNPTTLGEQRTKRQAISAEPTAIDI------QELSHVTLPFYPKSPQSKELIKEAILDNDFMKNLEISQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKESVKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEIVSKLADVLEETHYESGDYIIRQGARGDTFFIISKGKVNVTREDSPG-EDPIFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFGNLKLADFNIIDTLGVGGFGRVELVQLKSDECKTFAMKILKKRHIVDTRQQEHIRSEKQIMQSAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNEDPPPDDNSGWDIDF 685
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Match: camk4 (calcium/calmodulin-dependent protein kinase IV [Source:Xenbase;Acc:XB-GENE-5911781])

HSP 1 Score: 739.569 bits (1908), Expect = 0.000e+0
Identity = 383/684 (55.99%), Postives = 489/684 (71.49%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI------------PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I  L+ +L  ++++            P  L ++  +   ISAEP  ++       + L+HV      K  ++KE +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E + K+ADVL E HY   DYIIR+GARGDTF+IISKGKV VT++     E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ +D  ++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  FDD T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQRLQNELDKYRSVIKPATQQVHKQNPTTLGEQRTKRQAISAEPTAIDI------QELSHVTLPFYPKSPQSKELIKEAILDNDFMKNLEISQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKESVKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEIVSKLADVLEETHYESGDYIIRQGARGDTFFIISKGKVNVTREDSPG-EDPIFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFGNLKLADFNIIDTLGVGGFGRVELVQLKSDECKTFAMKILKKRHIVDTRQQEHIRSEKQIMQSAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNEDPPPDDNSGWDIDF 685
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Match: ptafr (platelet activating factor receptor [Source:Xenbase;Acc:XB-GENE-968925])

HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0
Identity = 327/659 (49.62%), Postives = 437/659 (66.31%), Query Frame = 3 
Query:  339 LKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLV--RAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNL-------LIRDLVNF--NRDYEDEKLSDKQRSIFNYLQ---------------------LKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            LK F  +     K++    G+SAEP       D            K T E ++   A+ +N FM+ +  +QI D+VE MY        +II++GE GS ++ L DG  E+  + + L  +   + FGELAILYNCTRTASV+A T  + W +DRE FQ+IM K+   + EEY+ FL+SVP  KEL   KL+KIAD L    Y  DDYIIREG  G TF+IISKGKVKVT+      E + +I++L++G +FGEKAL  +DVR+ANI+A   D V+CLV+DR+++N        L++ L  +  N   +DE+   K      +L+                      ++L  V T+G+GGFGRVELV++ N+ +  FALK +KK HIV+ RQQEH+ +EK ILEE  S FIVKLY TFKD KY+YM++E CLGGE+W+ILRDR  FD+ TA+F T CV  A +YLH+KG++YRDLKPENL+LDS+GY K+ DFGF+KKI   +KTWTFCGTPEYVAPE+ILNKGH FS DFWSLGIL++ELLTG+PPF+  D M  YN+IL+GIE IE    ++K   +LI++L R+NP ERLG  K GI +++KH WF GFNW GL  R++  P+ P+++   DHS FDSYPPDE++PPD++SGWD +F
Sbjct:  132 LKTFSGLFSNSNKRKGAKEGVSAEPTSRYDGGDHPRFSFEKARVRKNTSEKILISDALNKNQFMKRMDHHQIQDMVECMYERIYLQGEFIIRQGEPGSQIFVLADGKAEVFQENKLLTSIPVWTTFGELAILYNCTRTASVKAITGVRTWALDREVFQNIMRKTAQSKHEEYLSFLKSVPLLKELPEHKLMKIADCLELEFYEMDDYIIREGEEGSTFFIISKGKVKVTQSTEGYKEPQ-YIKFLEKGDYFGEKALISDDVRSANILAYG-DRVECLVMDRETFNKTVGTYEELMKCLEGYVANLTLDDERRHAKSPVNERHLRAVSMELNKMKQTLARFPSASPFENLEIVTTLGVGGFGRVELVKVKNE-NLVFALKCIKKRHIVDNRQQEHIHSEKNILEEACSPFIVKLYCTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTAKFCTGCVTEAFEYLHQKGVLYRDLKPENLLLDSEGYVKLVDFGFAKKIFPGQKTWTFCGTPEYVAPEVILNKGHSFSVDFWSLGILLYELLTGSPPFTGPDQMIIYNLILQGIEKIEFYKNITKRPEDLIRRLCRENPAERLGNMKNGIADIKKHRWFNGFNWEGLNTRSLPSPLKPELEGPTDHSYFDSYPPDEEIPPDEVSGWDQDF 787
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Match: tnpo2 (transportin 2 [Source:Xenbase;Acc:XB-GENE-968452])

HSP 1 Score: 596.275 bits (1536), Expect = 0.000e+0
Identity = 316/697 (45.34%), Postives = 458/697 (65.71%), Query Frame = 3 
Query:  252 KLAKKEIEIKRLLETIQIKNEQIAELEKDLKY--FKNIPVKLQKKEVRGI--------GISAEPRGLNF-NYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDY------EDEKLSDKQRSIFNYL--------QLKDLC-------------FVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +L +K+ +I +L + +++K  QI +L+  L Y   +  P   QKK++           G+SAEP   ++ N  S    +  V K+   K+ +  AI+ NDF+R L A+ +  +V+ MY    + +  +IQEG  G+ +Y L DG++++      L QM  G+ FGELAILYNC RTA+V+A T  K+W +DR+ FQ+IMM S   + +EY  FL+       + + +L+    +   + Y+K DYIIREG  G+TF+II+KGKV VT+    + E +  I+ L  G +FGEKAL  EDVR+ANIIA + D   CLV+DRD++N ++   ++L  + R+Y       D    + ++S+ + +        QL++L               + T+G GGFGRVELV++  D   +FALK +KK HIV+T QQEHV  EK IL++++  FI++LY+TF+D KY+YM++EVCLGGE+W+ILRD   F++ TARF T CV+ A DYLH +GIVYRDLKPENL+LDS+GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPEII+N+GHDF AD+WSLGIL++ELLTG+PPFS +DP+K YN++LKGIE ++ P  + + + ++I++L R NP ERLG  K GI +++KH WF+GFNW GL  R +  P+  ++K   DHS FD++ P+ + PPD++SGWD  F
Sbjct:   54 ELQEKDEKILQLEKELEVKVIQIDKLQDALGYNVTQTSPKGSQKKKLLSAHRRQKAKEGVSAEPTSRHYYNPSSQNPDVTCVRKDSSAKKLITGAIMSNDFLRQLEASHVRCMVDCMYERVYSKSQLVIQEGAAGNHLYVLADGLLDVIQNSRLLGQMHPGTAFGELAILYNCKRTATVKAVTDSKIWVLDRQVFQNIMMSSAQAQHQEYFSFLRRYVGLFSVMIYRLLYT--IKNTDFYDKGDYIIREGEEGNTFFIIAKGKVCVTQAVEGSQEPQE-IKTLGVGDYFGEKALISEDVRSANIIA-EEDDTQCLVIDRDTFNQMVGTYQELQTYLREYVFQLALNDHDRRNARKSLHHSMSRDNSEVNQLRELVSKFSSTSPFRYLDVITTLGTGGFGRVELVKL-KDEDMTFALKCIKKKHIVDTHQQEHVYWEKNILQQINCSFIIRLYRTFRDAKYVYMLLEVCLGGELWSILRDTGPFEEGTARFCTGCVLEAFDYLHNRGIVYRDLKPENLLLDSEGYIKMVDFGFAKKIGPGKKTWTFCGTPEYVAPEIIMNRGHDFGADYWSLGILIYELLTGSPPFSGTDPIKIYNMVLKGIEKVDFPHRIGRRSEDVIRRLCRINPAERLGNRKNGISDIRKHKWFQGFNWEGLRNRKLLSPLKREIKGITDHSYFDNFLPESEEPPDELSGWDKNF 745
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Match: Prkg1 (protein kinase, cGMP-dependent, type I [Source:MGI Symbol;Acc:MGI:108174])

HSP 1 Score: 746.888 bits (1927), Expect = 0.000e+0
Identity = 383/670 (57.16%), Postives = 491/670 (73.28%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG+V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGQVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Match: Prkg1 (protein kinase, cGMP-dependent, type I [Source:MGI Symbol;Acc:MGI:108174])

HSP 1 Score: 731.095 bits (1886), Expect = 0.000e+0
Identity = 378/679 (55.67%), Postives = 490/679 (72.16%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQKKEVRGIGISAEPRGLN--FNYDSLA---KGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I +L+ +L  ++++  P   Q ++     +  EPR      + +  A   + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG+V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQAQKQSASTLQGEPRTKRQAISAEPTAFDIQDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGQVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF 686
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Match: Prkg2 (protein kinase, cGMP-dependent, type II [Source:MGI Symbol;Acc:MGI:108173])

HSP 1 Score: 622.854 bits (1605), Expect = 0.000e+0
Identity = 343/721 (47.57%), Postives = 470/721 (65.19%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKKEV-----------------RGI--GISAEPRGLNFNYD-----SLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKL-RQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRD-----------LVNFNRDYEDEKLSDKQRSIFNY----------LQLKD-------------LCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L E + +LAK+ + I  L E +Q K  Q+ +L+  +      P++    +V                 RG   G+SAEP    ++ +     S  K    V K+   K+ +  A+ +N F++ L   QI D+VE MY       S++I++GE G+ ++ L +G +E+  +GEKL   +   + FGELAILYNCTRTASV+A T  K W +DRE FQ+IM ++   R EEY  FL+SV   K L  +KL KI D L   +Y+K DYIIREG  G TF+I++KGKVKVT+    +++ +  I+ L +G++FGEKAL  +DVR+ANIIA ++D V CLV+DR+++N  +             +   NRD  DEK   K RS+ ++          +QLK+             L  +AT+G+GGFGRVELV++ N+ + +FA+K ++K HIV+T+QQEHV +EKRILEE+ S FIVKLY+TFKD KY+YM++E CLGGE+W+ILRDR  FD+ T++F  ACV  A DYLHR GI+YRDLKPENLILD+ GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPE+ILNKGHDFS DFWSLGIL++ELLTG PPFS  D M TYN+ILKGIE ++ P  +++   +LI++L R NP ERLG  K GI +++KH W  GFNW GL  R++  P+  ++   IDHS FD YPP++ VPPD++SGWD +F
Sbjct:   51 LKELREQLAKQTVAIAELTEELQSKCIQLNKLQDVIHVQGGSPLQASPDKVPLDVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKA--RVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYVIKQGEPGNHIFVLAEGRLEV-FQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEEYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQ-LIKTLQKGEYFGEKALISDDVRSANIIAEEND-VACLVIDRETFNQTVGTFDELQKYLEGYVATLNRD--DEKRHAK-RSMSSWKLSKALSLEMIQLKEKVARFSSTSPFQNLEIIATLGVGGFGRVELVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYPPEKGVPPDEMSGWDKDF 762
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Match: Prkg2 (protein kinase, cGMP-dependent, type II [Source:MGI Symbol;Acc:MGI:108173])

HSP 1 Score: 597.816 bits (1540), Expect = 0.000e+0
Identity = 331/698 (47.42%), Postives = 456/698 (65.33%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKKEV-----------------RGI--GISAEPRGLNFNYD-----SLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKL-RQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRD-----------LVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L E + +LAK+ + I  L E +Q K  Q+ +L+  +      P++    +V                 RG   G+SAEP    ++ +     S  K    V K+   K+ +  A+ +N F++ L   QI D+VE MY       S++I++GE G+ ++ L +G +E+  +GEKL   +   + FGELAILYNCTRTASV+A T  K W +DRE FQ+IM ++   R EEY  FL+SV   K L  +KL KI D L   +Y+K DYIIREG  G TF+I++KGKVKVT+    +++ +  I+ L +G++FGEKAL  +DVR+ANIIA ++D V CLV+DR+++N  +             +   NRD  DEK   K RS+ ++ +L     +  I +      E V++ N+ + +FA+K ++K HIV+T+QQEHV +EKRILEE+ S FIVKLY+TFKD KY+YM++E CLGGE+W+ILRDR  FD+ T++F  ACV  A DYLHR GI+YRDLKPENLILD+ GY K+ DFGF+KKIG  +KTWTFCGTPEYVAPE+ILNKGHDFS DFWSLGIL++ELLTG PPFS  D M TYN+ILKGIE ++ P  +++   +LI++L R NP ERLG  K GI +++KH W  GFNW GL  R++  P+  ++   IDHS FD YPP++ VPPD++SGWD +F
Sbjct:   51 LKELREQLAKQTVAIAELTEELQSKCIQLNKLQDVIHVQGGSPLQASPDKVPLDVHRKTSGLVSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKA--RVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYVIKQGEPGNHIFVLAEGRLEV-FQGEKLLSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEEYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQ-LIKTLQKGEYFGEKALISDDVRSANIIAEEND-VACLVIDRETFNQTVGTFDELQKYLEGYVATLNRD--DEKRHAK-RSMSSW-KLSKALSLEMIQLK-----EKVKVKNE-NVAFAMKCIRKKHIVDTKQQEHVYSEKRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFDYLHRLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNKGHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYPPEKGVPPDEMSGWDKDF 733
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Match: Prkg1 (protein kinase, cGMP-dependent, type I [Source:MGI Symbol;Acc:MGI:108174])

HSP 1 Score: 463.766 bits (1192), Expect = 1.322e-157
Identity = 232/379 (61.21%), Postives = 279/379 (73.61%), Query Frame = 3 
Query: 1098 LKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            + +EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL R                     WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:   27 ISEEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCR---------------------WFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF 382
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Match: sp|P00516|KGP1_BOVIN (cGMP-dependent protein kinase 1 OS=Bos taurus OX=9913 GN=PRKG1 PE=1 SV=2)

HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0
Identity = 385/670 (57.46%), Postives = 491/670 (73.28%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV VT++   N E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPN-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Match: sp|P0C605|KGP1_MOUSE (cGMP-dependent protein kinase 1 OS=Mus musculus OX=10090 GN=Prkg1 PE=1 SV=1)

HSP 1 Score: 746.888 bits (1927), Expect = 0.000e+0
Identity = 383/670 (57.16%), Postives = 491/670 (73.28%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG+V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPDEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGQVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDSDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Match: sp|Q13976|KGP1_HUMAN (cGMP-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PRKG1 PE=1 SV=3)

HSP 1 Score: 746.503 bits (1926), Expect = 0.000e+0
Identity = 383/670 (57.16%), Postives = 490/670 (73.13%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY   +YIIR+GARGDTF+IISKG V VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPS-EDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPEDNDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Match: sp|O77676|KGP1_RABIT (cGMP-dependent protein kinase 1 OS=Oryctolagus cuniculus OX=9986 GN=PRKG1 PE=1 SV=3)

HSP 1 Score: 739.954 bits (1909), Expect = 0.000e+0
Identity = 381/670 (56.87%), Postives = 489/670 (72.99%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PV---KLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNF-NRDYEDEKLSDKQRS---IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDED-VPPDDISGWDNEF 2219
            ++F   L  KE  IK L + +  K E+I EL++ L   +++ PV    +  +  R  GISAEP+     +D L +      K +++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+ Y +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+     KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY  ++Y IR+GARGDTF+IISKGKV VT++   + E+  F+R L +G WFGEKAL+ EDVRTAN+IA +   V CLV+DRDS+  LI  L +  N+ YED +   K  +    F  L+L D   + T+G+GGFGRVELVQ+ ++ S++FA+K LKK HIV+TRQQEH+ +EK+I++   S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFD +P D D  PPDD SGWD +F
Sbjct:    6 EDFAKILMLKEERIKELEKRLSEKEEEIQELKRKLHKCQSVLPVPSTHIGPRTTRAQGISAEPQTYRSFHD-LRQAFRKFTKFERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLAYVMEDGKVEVTKEGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENEEYSIRQGARGDTFFIISKGKVNVTREDSPS-EDPIFLRTLGKGDWFGEKALQGEDVRTANVIAAE--AVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAAFFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDGFPEDNDEPPPDDNSGWDIDF 671
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Match: sp|Q03043|KGP24_DROME (cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B OS=Drosophila melanogaster OX=7227 GN=for PE=1 SV=3)

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 372/707 (52.62%), Postives = 496/707 (70.16%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-PVKLQK-------------------------------------KEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQR--SIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNF-DSYPPDEDVPPDDISGWDNEF 2219
            + F   +  KE++I+ +   +Q K+ +IAEL+  L  F+++ P                                          +  R +GISAEP+    +  SL   L HV+     K+++++E +  AIL+NDFM++L   QI ++V+ MYPV   + + II+EG++GS+VY +EDG VE++ +G+ L  ++   + GELAILYNC RTA++ A T+C LW I+R+ FQ+IMM++G+ RQ EY  FL+SVP FK+L  + LIKI+DVL E HY + DYI+R+GARGDTF+IISKGKV+VT K     E E FIR L +G +FGEKAL+ +D+RTANII    DGV CLV+DR+++N LI +L      Y+DE   ++++    F  + L DL  +AT+G+GGFGRVELVQ   D S+SFALK++KK  IVETRQQ+H+++EK I+ E + +FIVKL+KTFKD+KYLYM+ME CLGGE+WTILRD+  FDD T RFYTACVV A DYLH + I+YRDLKPENL+L+ +GY K+ DFGF+KK+   RKTWTFCGTPEYVAPE+ILN+GHD SAD+WSLG+LMFELLTGTPPF+ SDPM+TYNIILKGI+AIE P  +++NA NLIKKL RDNP ERLGY + GI E+QKH WF+GF W GL    ++PPI P VKS +D +NF D  P  E  PPDD++GWD +F
Sbjct:  389 ERFIQIIQAKELKIQEMQRALQFKDNEIAELKSHLDKFQSVFPFSRGSAAGCAGTGGASGSGAGGSGGSGPGTATGATRKSGQNFQRQRALGISAEPQ----SESSLL--LEHVSFPKYDKDERSRELIKAAILDNDFMKNLDLTQIREIVDCMYPVKYPAKNLIIKEGDVGSIVYVMEDGRVEVSREGKYLSTLSGAKVLGELAILYNCQRTATITAITECNLWAIERQCFQTIMMRTGLIRQAEYSDFLKSVPIFKDLAEDTLIKISDVLEETHYQRGDYIVRQGARGDTFFIISKGKVRVTIKQQDTQE-EKFIRMLGKGDFFGEKALQGDDLRTANIICESADGVSCLVIDRETFNQLISNLDEIKHRYDDEGAMERRKINEEFRDINLTDLRVIATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIVKLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIYRDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYWSLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAERLGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNFDDYPPDPEGPPPDDVTGWDKDF 1088
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Match: G4LX39 (cGMP-dependent protein kinase,putative OS=Schistosoma mansoni OX=6183 GN=Smp_168670 PE=4 SV=1)

HSP 1 Score: 823.543 bits (2126), Expect = 0.000e+0
Identity = 392/587 (66.78%), Postives = 476/587 (81.09%), Query Frame = 3 
Query:  462 VAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRS-IFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            + K   TK  + +AIL NDFM+HL   QIS +V++M P+     SWIIQEGE+GSVVY LEDG VE+   GE+LR+M  G++FGELAILYNCTRTASVRA T CKLW IDR  FQSIMM +GI++Q EYVKFL+SVPTFK+L +E L K+A VLG  HY  D+Y+IREG RG+TFYII+ GKVKVTK  G N  NE FIRY+ RG WFGEKAL DEDVRTANIIA+   GVDCL+LDRDSYN+LI+DLV+F R Y DEK +  QR   F+ ++L D   V+TIGIGGFGRV+LV +  D+ Q FALKKLKK++IVET+QQEHVINEK IL E + EFIVKLY+T+KD++YLY+++EVCLGGE+WT+LR+ T FDD TARFY+ACVV AL+YLHR+GIVYRDLKPENL+LDS+G+CK+TDFGF+K+IG+  KTWTFCGTPEYVAPE+ILNKGHDF+ DFW+LGILMFELLTGTPPF++SDPMK YNIILKGI  IE P ++++NA  LIKKL RD P +RLG  K GI+EV+ H WFEGF+WNGL+ R IQ PI PK+ S  D SNFDSY  +E++PP+D +GWD +F
Sbjct:  598 IEKPAHTKALITQAILNNDFMKHLDKRQISKIVDSMCPLGCARLSWIIQEGEVGSVVYVLEDGYVEVQKAGERLREMGPGTVFGELAILYNCTRTASVRAITDCKLWAIDRPCFQSIMMFTGIQKQTEYVKFLKSVPTFKDLNLEVLGKVAVVLGSEHYEPDEYVIREGERGNTFYIITGGKVKVTKNRG-NECNEQFIRYMTRGDWFGEKALTDEDVRTANIIAMPPRGVDCLMLDRDSYNVLIKDLVSFERSYPDEKPTISQREKQFSDIKLTDFTVVSTIGIGGFGRVQLVYLNKDKRQCFALKKLKKHYIVETKQQEHVINEKNILMETNHEFIVKLYRTYKDQRYLYILLEVCLGGELWTLLRNSTAFDDSTARFYSACVVEALNYLHRRGIVYRDLKPENLLLDSQGFCKMTDFGFAKRIGYGNKTWTFCGTPEYVAPEVILNKGHDFTVDFWALGILMFELLTGTPPFTSSDPMKIYNIILKGINTIEFPKSITRNAQCLIKKLCRDAPAQRLGARKSGIIEVKNHAWFEGFDWNGLIARTIQVPITPKISSPTDLSNFDSYSEEEELPPEDTTGWDKDF 1183
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Match: A0A267FPA9 (cGMP-dependent protein kinase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig003256g1 PE=3 SV=1)

HSP 1 Score: 819.305 bits (2115), Expect = 0.000e+0
Identity = 398/661 (60.21%), Postives = 508/661 (76.85%), Query Frame = 3 
Query:  273 EIKRLLETIQIKNEQIAELEKDLKYFKNI-------PVKLQKKEV---RGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEIT-IKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI-FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +I  L   +++K+++IAEL   +  ++++       PV      V   RG+GISAEP+  N    S       V K+  T++ + RAILEN FM++L   QIS++++ MYP+T  +N+ II+ GEIGS+VY +E+G  E+T  KG+K+ ++ +G++FGELAILYNC RTA+V+A + CKLW IDR++FQSIMMK+G+ + +EY++FL+SVP FKEL  E L K+ADVL  +HY   +YIIR+GA+G+TFYII+KG V+VTK+     E+  FIR + RG WFGEKAL +EDVRTANII  D +GVDCLVL+R+SY  LI DL    R Y DE  +   RS  F  L LKDL  +AT+G+GGFGRVELV+I ND S+SFALK+LKK+HIVETRQQEH++NE+ IL E + +FIVKLY+TFKDRKYLYM+ME CLGGE+WTILRD+  FDD T RFY  CVV AL YLHRKGIVYRDLKPENL+LD+ GYCKITDFGF+K+IGF +KTWTFCGTPEYV PE+ILNKGHD +ADFWSLG+LMFELLTGTPPF+ SDPMKTYNIILKGI+A++ P  +S+NA NL+KKL RDNP ERLG G+ G++EV KH+WFEGFNW G+  + + PPI+PKV SA+D SNFD YP D + PPDD+SGWD +F
Sbjct:   50 QISDLKSQVRMKDKRIAELLSQVDKYQSVINSAAGSPVHTAATTVKRQRGVGISAEPQ--NEQLVSQMSTGKIVPKDAGTRDLIRRAILENAFMKNLENAQISEIIDYMYPMTHKTNALIIKLGEIGSLVYVMEEGSAEVTNTKGDKINEIGSGTVFGELAILYNCKRTATVKALSNCKLWAIDRQTFQSIMMKTGLLKHKEYMEFLKSVPAFKELPGETLSKLADVLEADHYPNGEYIIRQGAKGNTFYIIAKGNVRVTKRDSATGES-VFIRNMGRGDWFGEKALNEEDVRTANIIVEDPNGVDCLVLNRESYKQLIGDLAILGRKYSDESTAQPSRSEEFKGLTLKDLFIIATLGVGGFGRVELVRIRNDNSRSFALKQLKKHHIVETRQQEHIMNERSILAEANCDFIVKLYRTFKDRKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYIGCVVEALQYLHRKGIVYRDLKPENLLLDTTGYCKITDFGFAKRIGFGKKTWTFCGTPEYVPPEVILNKGHDLTADFWSLGVLMFELLTGTPPFTASDPMKTYNIILKGIDAVDFPRRISRNAQNLVKKLCRDNPTERLGVGRGGVMEVSKHIWFEGFNWAGMNSKTLTPPILPKVSSAVDASNFDEYPADNEHPPDDVSGWDKDF 707
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Match: A0A267GV06 (cGMP-dependent protein kinase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011874g1 PE=3 SV=1)

HSP 1 Score: 818.92 bits (2114), Expect = 0.000e+0
Identity = 398/661 (60.21%), Postives = 508/661 (76.85%), Query Frame = 3 
Query:  273 EIKRLLETIQIKNEQIAELEKDLKYFKNI-------PVKLQKKEV---RGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEIT-IKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI-FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +I  L   +++K+++IAEL   +  ++++       PV      V   RG+GISAEP+  N    S       V K+  T++ + RAILEN FM++L   QIS++++ MYP+T  +N+ II+ GEIGS+VY +E+G  E+T  KG+K+ ++ +G++FGELAILYNC RTA+V+A + CKLW IDR++FQSIMMK+G+ + +EY++FL+SVP FKEL  E L K+ADVL  +HY   +YIIR+GA+G+TFYII+KG V+VTK+     E+  FIR + RG WFGEKAL +EDVRTANII  D +GVDCLVL+R+SY  LI DL    R Y DE  +   RS  F  L LKDL  +AT+G+GGFGRVELV+I ND S+SFALK+LKK+HIVETRQQEH++NE+ IL E + +FIVKLY+TFKDRKYLYM+ME CLGGE+WTILRD+  FDD T RFY  CVV AL YLHRKGIVYRDLKPENL+LD+ GYCKITDFGF+K+IGF +KTWTFCGTPEYV PE+ILNKGHD +ADFWSLG+LMFELLTGTPPF+ SDPMKTYNIILKGI+A++ P  +S+NA NL+KKL RDNP ERLG G+ G++EV KH+WFEGFNW G+  + + PPI+PKV SA+D SNFD YP D + PPDD+SGWD +F
Sbjct:   50 QISDLKSQVRMKDKRIAELLSQVDKYQSVINSAAGSPVHTAATTVKRQRGVGISAEPQ--NEQLVSQMSTGKIVPKDAGTRDLIRRAILENAFMKNLENAQISEIIDYMYPMTHKTNALIIKLGEIGSLVYVMEEGSAEVTNTKGDKINEIGSGTVFGELAILYNCKRTATVKALSNCKLWAIDRQTFQSIMMKTGLLKHKEYMEFLKSVPAFKELPGETLSKLADVLEADHYPNGEYIIRQGAKGNTFYIIAKGNVRVTKRDSATGES-VFIRNMGRGDWFGEKALNEEDVRTANIIVEDPNGVDCLVLNRESYKQLIGDLAILGRKYSDESTAQPTRSEEFKGLTLKDLFIIATLGVGGFGRVELVRIRNDNSRSFALKQLKKHHIVETRQQEHIMNERSILAEANCDFIVKLYRTFKDRKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYIGCVVEALQYLHRKGIVYRDLKPENLLLDTTGYCKITDFGFAKRIGFGKKTWTFCGTPEYVPPEVILNKGHDLTADFWSLGVLMFELLTGTPPFTASDPMKTYNIILKGIDAVDFPRRISRNAQNLVKKLCRDNPTERLGVGRGGVMEVSKHIWFEGFNWAGMNSKTLTPPILPKVSSAVDASNFDEYPADNEHPPDDVSGWDKDF 707
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Match: A0A4E0RB43 (cGMP-dependent protein kinase 1 OS=Fasciola hepatica OX=6192 GN=D915_003409 PE=4 SV=1)

HSP 1 Score: 806.209 bits (2081), Expect = 0.000e+0
Identity = 387/584 (66.27%), Postives = 468/584 (80.14%), Query Frame = 3 
Query:  468 KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            K ++TK  + +AI++NDFM+HL + QI+++VE+M P+     SWI++EGEIGSVVY LE G VE+   GE++R+M  G++FGELAILYNCTRTASV+A   C LW IDR  FQSIMM++G+RRQ++YVKFL+SVPTF EL  E LIK+ADVLG  HYN  DY+IREGARG+TF+IIS GKVKVTK      + E FIRY++RG WFGEKAL DEDVRTANIIA   DGVDCL+LDRDSYNLLI+DLV+F R Y DE+   +  S F+  QL DL  V+TIG+GGFGRV LV +  D+ QSFALKKLKK +IVETRQQEH++NEK IL E D++FIVKL+KTFKDR+YLY ++E CLGGE+WTILR+ T F+D T RFYTACVV A+ YLHRKGI+YRDLKPENL+LD+ GYCK+TDFGF+KKIGF  KTWTFCGTPEYVAPEIILNKGHDFS D WSLGIL+FELLTGTPPF++ DPM+TYN ILKGI AIE P  + +NA  LIKKL R+NP ERLG  + GI E+QKHVWFEGFNW GL  R +  PI+PKV SA D SNFD Y  D ++ P++++ WD +F
Sbjct:  513 KSEQTKTLITQAIMDNDFMKHLDSGQIAEIVESMCPLRCARMSWIVREGEIGSVVYVLEAGYVEVLQSGERIREMGPGTVFGELAILYNCTRTASVKALIDCSLWAIDRHCFQSIMMRTGMRRQKDYVKFLKSVPTFSELSDEVLIKVADVLGACHYNPGDYVIREGARGNTFFIISDGKVKVTKNRATVGD-EQFIRYMERGDWFGEKALSDEDVRTANIIAAAPDGVDCLMLDRDSYNLLIKDLVSFARTYPDEQHVPRI-SQFSETQLADLELVSTIGLGGFGRVLLVTLKKDKRQSFALKKLKKQYIVETRQQEHILNEKSILLEADNDFIVKLHKTFKDRRYLYFLLEACLGGELWTILRNCTSFEDSTTRFYTACVVEAIAYLHRKGIIYRDLKPENLLLDNHGYCKMTDFGFAKKIGFGSKTWTFCGTPEYVAPEIILNKGHDFSVDLWSLGILVFELLTGTPPFNSPDPMRTYNFILKGINAIEFPKKIGRNAQCLIKKLCRENPTERLGTRRGGISELQKHVWFEGFNWVGLRARTLIAPIVPKVTSATDVSNFDRYTEDTELAPEELTNWDRDF 1094
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Match: A0A267FLY4 (cGMP-dependent protein kinase OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig030852g1 PE=3 SV=1)

HSP 1 Score: 800.816 bits (2067), Expect = 0.000e+0
Identity = 393/669 (58.74%), Postives = 504/669 (75.34%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQ-----IKNEQIAELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEIT-IKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI-FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +DE + +L  K+  I++L E +      +  EQ       L+   +   +L  +  R + IS E      N +     +    K  +T++ + RAILEN FM++L   QIS++++ MYP+T  +N+ II+ GEIGS+VY +E+G  E+T  KG+K+ ++ +G++FGELAILYNC RTA+V+A T CKLW IDR++FQSIMMK+G+ + +EY++FL+SVP FKEL  E L K+ADVL  +HY   +YIIR+GA+G+TFYII+KG V+VTK+     E+  FIR + RG WFGEKAL +EDVRTANII  D +GVDCLVL+R+SY  LI DL    R Y DE  +   RS  F  L LKDL  +AT+G+GGFGRVELV+I ND S+SFALK+LKK+HIVETRQQEH++NE+ IL + + +FIVKLY+TFKDRKYLYM+ME CLGGE+WTILRD+  FDD T RFY  CVV AL YLHRKGIVYRDLKPENL+LD+ GYCKITDFGF+K+IGF +KTWTFCGTPEYV PE+ILNKGHD +ADFWSLG+LMFELLTGTPPF+ SDPMKTYNIILKGI+A++ P  +S+NA NL+KKL RDNP ERLG G+ G++EV KH+WFEGFNW G+  + + PPI+PKV SA+D SNFD YP D + PPDD+SGWD +F
Sbjct:   25 IDELEIELDVKDARIEQLQEEVGRLQSLLSREQPERHAASLQSAASFDRQLVPRTKR-VAISGESSAEFANSN-----VKPCEKSTRTRDLIRRAILENAFMKNLENAQISEIIDYMYPMTHKTNALIIKLGEIGSLVYVMEEGSAEVTNTKGDKINEIGSGTVFGELAILYNCKRTATVKALTNCKLWAIDRQTFQSIMMKTGLLKHKEYMEFLKSVPAFKELPGETLSKLADVLEADHYPNGEYIIRQGAKGNTFYIIAKGNVRVTKRDSATGES-VFIRNMGRGDWFGEKALNEEDVRTANIIVEDPNGVDCLVLNRESYKQLIGDLAILGRKYSDESTAQPSRSEEFKGLTLKDLFIIATLGVGGFGRVELVRIRNDNSRSFALKQLKKHHIVETRQQEHIMNERSILADANCDFIVKLYRTFKDRKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYIGCVVEALQYLHRKGIVYRDLKPENLLLDTTGYCKITDFGFAKRIGFGKKTWTFCGTPEYVPPEVILNKGHDLTADFWSLGVLMFELLTGTPPFTASDPMKTYNIILKGIDAVDFPRRISRNAQNLVKKLCRDNPTERLGVGRGGVMEVSKHIWFEGFNWAGMNSKTLTPPILPKVSSAVDASNFDEYPADNEHPPDDVSGWDKDF 686
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Match: prkg1b (protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:ZDB-GENE-080225-40])

HSP 1 Score: 734.561 bits (1895), Expect = 0.000e+0
Identity = 375/661 (56.73%), Postives = 482/661 (72.92%), Query Frame = 3 
Query:  264 KEIEIKRLLETIQIKNEQIAELEKDLKYFKNI----PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFN-RDYEDEKLSDK---QRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            KE  I+ +   +  K E+IAEL++ L   +++    P+ +  +  R  GISAEP+         ++ L   AK  ++KE +  AIL+NDFM++L  +QI ++            S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF+ L  E L K+ADVL E HY+  +YIIR+GARGDTF+IISKGKV VT++   ++    ++R L +G WFGEKAL+ ED+RTAN+IA D   V CLV+DRDS+  LI  L + + + YED     K   + + F+ L+L D   + T+G+GGFGRVELVQ+ ++ +++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S  D SNFDS+P D ED PPDD SGWD +F
Sbjct:   15 KEERIREMELRLAEKEEEIAELKRKLHKCQSVLPSAPL-MGPRTRRAQGISAEPQPFTSFQQLTSEALRKHAKSDRSKELIKEAILDNDFMKNLELSQIQEI-----------ESCIIKEGDVGSLVYVMEDGKVEVTKEGMKLCTMGPGKVFGELAILYNCTRTATVQTLTNVKLWAIDRQCFQTIMMRTGLIKHAEYMEFLKSVPTFQGLAEEILSKLADVLEETHYDDGEYIIRQGARGDTFFIISKGKVNVTREDSPSD-TPVYLRALGKGDWFGEKALQGEDIRTANVIAAD--AVTCLVIDRDSFKHLIGGLDDVSSKGYEDAGAKAKYEAENAFFSNLKLADFNIIDTLGVGGFGRVELVQLKSEETKTFAMKILKKRHIVDTRQQEHIRSEKHIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPDVSSPTDTSNFDSFPEDSEDPPPDDNSGWDTDF 660
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Match: prkg1a (protein kinase cGMP-dependent 1a [Source:ZFIN;Acc:ZDB-GENE-040426-1308])

HSP 1 Score: 644.04 bits (1660), Expect = 0.000e+0
Identity = 351/684 (51.32%), Postives = 455/684 (66.52%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQ---------KKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDG-VDCLVLDRDSYNLLIRDLVNFN----RDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I +L+ +L  ++++  P   Q         ++  +   ISAEP   +       + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV  + +S II+EG++GS+VY +EDG VE+T +G KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY++FL+SVPTF  L  E L K+ DVL E HY   DYIIR+GARGDTF+IISKGKV VT++   + E   ++R L +G WFGEKAL+   +   N   +     ++C      SY  LI  L + +     D E +   + + + F  L L D   + T+G+GGFGRVELVQ+ +D  ++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FI    +TFKD KYLYM+ E CL      I   R  FDD T RFYTACVV A  YLH KGI+YRDLKPENLILD +G     DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RD P ERLG  K G+ ++QKH WFEGFNW GL    + PP  P V SA D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQKLQNELDKYRSVIRPATQQVQKHSELQEQQRTKRQAISAEPTAFDI------QELSHVTLPFNPKSAQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYSKDSCIIKEGDVGSLVYVMEDGKVEVTKEGLKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHAEYMEFLKSVPTFHGLPEEILSKLGDVLEETHYEDGDYIIRQGARGDTFFIISKGKVTVTREDAASQET-VYLRSLGKGDWFGEKALQGNQISCLNTDLITLSTFINCW-----SYKHLIGGLEDVSSKGSEDAEAKAKYEAENAFFFNLHLSDFNIIDTLGVGGFGRVELVQLKSDEYKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIT--VQTFKDSKYLYMLHEACLEESCGPIPETRGSFDDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRG-----DFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAANLIKKLCRDTPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPSSP-VTSATDTSNFDSFPEDNEDPPPDDNSGWDGDF 674
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Match: prkg2 (protein kinase cGMP-dependent 2 [Source:NCBI gene;Acc:103030142])

HSP 1 Score: 607.831 bits (1566), Expect = 0.000e+0
Identity = 317/713 (44.46%), Postives = 453/713 (63.53%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-----PVK--------------LQKKEVRGIGISAEPRGLNFNYDSLAK---GLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDY-----EDEKLSDKQRSIFN---------------------YLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            + + +++LA++   I  + + ++ K  Q+ +L++ LK   ++     P K              L K++    G+SAEP    ++  S+ K       V KE   K+ L  A+ +N ++R L   QI D+VE MY  T     ++I++GE G+ ++ L DG +++    + L  +   + FGELAILYNCTRTASV+A +  + W +DRE F +IM  +   R E++  FL+SV     L  +KL KI D L   +Y+K DY+IREG  G+TFYII+        +  K++E    I  L +G +FGEKAL  +DVR+ANIIA D DGV+CLV+DR+++   +    +L  + + Y      D+K  + +RS  N                      L   +L  +AT+GIGGFGRVELV++ N+ + +FALK +KK HIV+ RQ+EH+ +E+RIL E +S FIVK+Y+TFKD KY+YM++E CLGGE+W++LRDR  F++ TA+F   CV  A +YLH K I+YRDLKPENL+LDS GY K+ DFGF+KK+   +KTWTFCGTPEYVAPEIILNKGH  S DFW+LGIL+FELLTG+PPF+ SD M TY  ILKG+E ++ P  +SK   +LI+KL + NP ERLG  K GI++++KH WF GF+W+GL  R +  P+  +VK   DHS FD+YPP++++PPD+ISGWD +F
Sbjct:   58 IKQLEDQLAQQNQAIADISDALRNKCFQLTKLQEALKNQGDLELLSSPTKTKFSQRLSGLLRETLNKRKGAKAGVSAEPSSRTYDSSSMPKFYFESARVWKEPSVKKLLTDALNKNRYLRRLEGQQIKDMVECMYERTYQQGEFVIKQGEPGNHLFVLADGNIDVYQNNKLLTSIAVWTTFGELAILYNCTRTASVKAASGVRTWVLDREVFHNIMRMTAEARHEQHRSFLRSVSLLASLPEDKLTKIVDCLEVEYYDKGDYVIREGEEGNTFYIIA-RGKVKVTQSTKDHEEPQVINTLQKGDYFGEKALISDDVRSANIIA-DEDGVECLVIDRETFTQTVGTFDELKKYLQGYVETLARDDKKRNAKRSGSNTPPSSPLSLDRIQLREKNFTSTLSFSNLEIIATLGIGGFGRVELVKVKNE-NVTFALKCIKKRHIVDNRQEEHIHSERRILSETNSPFIVKMYRTFKDSKYVYMLLEACLGGEIWSMLRDRGSFEENTAKFCVGCVTEAFEYLHNKAIIYRDLKPENLMLDSDGYVKLVDFGFAKKMKCGQKTWTFCGTPEYVAPEIILNKGHGLSVDFWALGILIFELLTGSPPFTGSDQMMTYTFILKGMEKMDFPKKISKRPGDLIRKLCKQNPSERLGNMKNGIMDIKKHRWFTGFSWSGLKARTLNSPLKREVKGPTDHSYFDNYPPEDEIPPDEISGWDMDF 767
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Match: ENSAMXT00000002114.2 (cGMP-dependent protein kinase 2-like [Source:NCBI gene;Acc:103041230])

HSP 1 Score: 603.979 bits (1556), Expect = 0.000e+0
Identity = 313/658 (47.57%), Postives = 451/658 (68.54%), Query Frame = 3 
Query:  348 FKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLN----HVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDY------EDEK---------------------LSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            F  + V++ ++     G+SAEP   +F  +   + ++     + K+   K+ +  AI+ NDF++ L      ++V+ MY    T+N  +IQEGE G+ +Y L +G++E+   G+ L QM  G+ FGELAILYNC RTA+V+A T+  +W +DR++FQSIMM+S   R EEY  FL+SV   K+L  EKL KI D L  ++++K +YIIREG  G+TF+II+KG+V VT+     +E    I+ L  G +FGEKAL  EDVR+ANIIA ++D   CLV+DRD++N ++    +L  + R+Y       DE+                     L +K   + +   L+ L  +AT+G+GGFGRVELV++ N+ + +FALK +KK HIV+TRQQEH+ +EK IL++ +  FIV+L++TF+D KY+YM++EVCLGGE+W++LRD + F++ TARF   CV+ A DYLH  GIVYRDLKPENL+LD++GY K+TDFGF+K+IG  +KTWTFCGTPEYVAPE+I+NKGHDF AD WSLGIL+FELL G+PPFS SDP+K Y ++L GIE +++P  +SK   +LI++L + NP ERLG  K GI++++KH WF+GFNW GL  R +  P+  ++   +DHS+FD +PP+ + PPD++SGWD +F
Sbjct:  116 FHRVAVEVHRRLKAKEGVSAEPTSGHFCKEHRTQHVSIERTRIRKDSGIKKLINEAIMNNDFLKKLEPQHTREMVDCMYEKVYTANQLVIQEGEPGNYLYVLAEGLLEVIQNGKLLGQMRPGTAFGELAILYNCKRTATVKAVTQSHIWALDRQTFQSIMMRSTQARHEEYFSFLRSVSLLKDLPEEKLAKIVDCLEIDYFDKGEYIIREGEEGNTFFIIAKGEVSVTQSTEGYSE-PLEIKILGVGDYFGEKALISEDVRSANIIAKEND-TQCLVVDRDNFNQMVGTYEELQAYLREYVEQLSINDERRIAATQSPLYERSPQAAELRSLHEKAARLSSCSFLQQLQIIATLGMGGFGRVELVKLKNEDT-AFALKCIKKKHIVDTRQQEHIYSEKNILQQTNCNFIVRLFRTFRDEKYVYMLLEVCLGGELWSVLRDMSFFEEATARFCIGCVLEAFDYLHGMGIVYRDLKPENLLLDAEGYVKMTDFGFAKRIGLGKKTWTFCGTPEYVAPEVIMNKGHDFGADCWSLGILIFELLIGSPPFSGSDPIKIYTMVLHGIEKVDIPKRISKRPEDLIRRLCKLNPAERLGNKKNGIIDIKKHKWFQGFNWEGLRRRKLASPLRRELNGPLDHSHFDMFPPELEEPPDELSGWDKDF 770
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Match: prkg2 (protein kinase cGMP-dependent 2 [Source:NCBI gene;Acc:103030142])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 309/688 (44.91%), Postives = 444/688 (64.53%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI-----PVK--------------LQKKEVRGIGISAEPRGLNFNYDSLAK---GLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDY-EDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            + + +++LA++   I  + + ++ K  Q+ +L++ LK   ++     P K              L K++    G+SAEP    ++  S+ K       V KE   K+ L  A+ +N ++R L   QI D+VE MY  T     ++I++GE G+ ++ L DG +++    + L  +   + FGELAILYNCTRTASV+A +  + W +DRE F +IM  +   R E++  FL+SV     L  +KL KI D L   +Y+K DY+IREG  G+TFYII++GKVKVT+    ++E    I  L +G +FGEKAL  +DVR+ANIIA D DGV+CLV+DR+++   +    +L  + + Y E     DK+R+   +L       +A            V++ N+ + +FALK +KK HIV+ RQ+EH+ +E+RIL E +S FIVK+Y+TFKD KY+YM++E CLGGE+W++LRDR  F++ TA+F   CV  A +YLH K I+YRDLKPENL+LDS GY K+ DFGF+KK+   +KTWTFCGTPEYVAPEIILNKGH  S DFW+LGIL+FELLTG+PPF+ SD M TY  ILKG+E ++ P  +SK   +LI+KL + NP ERLG  K GI++++KH WF GF+W+GL  R +  P+  +VK   DHS FD+YPP++++PPD+ISGWD +F
Sbjct:   58 IKQLEDQLAQQNQAIADISDALRNKCFQLTKLQEALKNQGDLELLSSPTKTKFSQRLSGLLRETLNKRKGAKAGVSAEPSSRTYDSSSMPKFYFESARVWKEPSVKKLLTDALNKNRYLRRLEGQQIKDMVECMYERTYQQGEFVIKQGEPGNHLFVLADGNIDVYQNNKLLTSIAVWTTFGELAILYNCTRTASVKAASGVRTWVLDREVFHNIMRMTAEARHEQHRSFLRSVSLLASLPEDKLTKIVDCLEVEYYDKGDYVIREGEEGNTFYIIARGKVKVTQSTK-DHEEPQVINTLQKGDYFGEKALISDDVRSANIIA-DEDGVECLVIDRETFTQTVGTFDELKKYLQGYVETLARDDKKRNAKWFL-------IAVCS-------SQVKVKNE-NVTFALKCIKKRHIVDNRQEEHIHSERRILSETNSPFIVKMYRTFKDSKYVYMLLEACLGGEIWSMLRDRGSFEENTAKFCVGCVTEAFEYLHNKAIIYRDLKPENLMLDSDGYVKLVDFGFAKKMKCGQKTWTFCGTPEYVAPEIILNKGHGLSVDFWALGILIFELLTGSPPFTGSDQMMTYTFILKGMEKMDFPKKISKRPGDLIRKLCKQNPSERLGNMKNGIMDIKKHRWFTGFSWSGLKARTLNSPLKREVKGPTDHSYFDNYPPEDEIPPDEISGWDMDF 728
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 385.956 bits (990), Expect = 1.015e-128
Identity = 173/308 (56.17%), Postives = 233/308 (75.65%), Query Frame = 3 
Query: 1296 VATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +AT+G+GGFGRV+LV++  D   +FALK LKK  +VE+RQQEHV +EKRIL+E    FIV+ Y+TF+D+K+++++ME CLGGE+W++LRD   F +V+ARF  ACVV AL YLH +GI+YRDLKPENL+LD++GY K+ DFGF+KK+   RK WTFCGTPEYV PE+I+N+GHD  AD W+LG+L++ELL G PPFS +DPMKTYN IL G+E +  P  + K A ++I++L R NP ERLG  K G+ +V+KH WF+GF+W  L    +  P+  +V    D  NFD +P D DVPPD+ SGWD++F
Sbjct:   37 IATLGVGGFGRVQLVKL-KDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPEDLDVPPDETSGWDHDF 343
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002201.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36797:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002201.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 326.25 bits (835), Expect = 1.270e-106
Identity = 159/308 (51.62%), Postives = 208/308 (67.53%), Query Frame = 3 
Query: 1296 VATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +AT+G+GGFGRV+LV++  D   +FALK LKK  +VE+RQQEHV +EKRIL+E    FIV+                   GG           F +V+ARF  ACVV AL YLH +GI+YRDLKPENL+LD++GY K+ DFGF+KK+   RK WTFCGTPEYV PE+I+N+GHD  AD W+LG+L++ELL G PPFS +DPMKTYN IL G+E +  P  + K A ++I++L R NP ERLG  K G+ +V+KH WF+GF+W  L    +  P+  +V    D  NFD +P D DVPPD+ SGWD++F
Sbjct:    1 IATLGVGGFGRVQLVKL-KDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVR-------------------GG-----------FQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPEDLDVPPDETSGWDHDF 277
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 241.121 bits (614), Expect = 5.315e-74
Identity = 113/272 (41.54%), Postives = 176/272 (64.71%), Query Frame = 3 
Query: 1362 QSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDE 2177
            Q  +LK  K+  +V+ +Q EH +NEKRIL+ +   F+V+L  +FKD   LYM++E   GGE+++ LR    F +  +RFY A +V+A +YLH   ++YRDLKPENL++D +GY ++TDFGF+K++    +TWT CGTPEY+APEIIL+KG++ + D+W+LG+L++E+  G PPF    P++ Y  I+ G   +  P   S +  +L++ L + +  +R G  K G+ +++ H WF   +W  +  R ++ P IPK K   D SNFD Y  +E
Sbjct:    5 QHVSLKATKRTKVVKLKQVEHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEE 272
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 198.749 bits (504), Expect = 4.626e-56
Identity = 126/335 (37.61%), Postives = 179/335 (53.43%), Query Frame = 3 
Query: 1263 FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLH-RKGIVYRDLKPENLILDSKGYCKITDFGFSKK-IGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDV---PP---DDISGWDNE----FEMFS 2231
            F+YL+L        +G G FG+V LV+      Q +A+K LKK  IV   +  H + E R+L+     F+  L  +F+    L  +ME   GGE++  L    VF +   RFY A +V ALDYLH  K +VYRDLK ENL+LD  G+ KI DFG  K+ I       TFCGTPEY+APE++ +  +  + D+W LG++M+E++ G  PF   D  K + +IL  +E I  P T+S +A  L+  L + +P +RLG G     E+ +H +F G  W  +  R + PP  P+V S  D   FD     + +   PP   D +   DNE    F  FS
Sbjct:  150 FDYLKL--------LGKGTFGKVILVR-EKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELIL--MEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDEEFTAQTITITPPDRFDSMESLDNERRPHFPQFS 473
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 196.052 bits (497), Expect = 1.143e-55
Identity = 110/300 (36.67%), Postives = 177/300 (59.00%), Query Frame = 3 
Query: 1272 LQLK--DLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRIL-EEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKK-IGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFD 2159
            LQ K  D  F+  +G G FG+V L +  +D    +A+K +KK  I++ ++++H++ E+ +L + V   F+V L+ +F+    LY +M+   GGE++  L+ +  F +  A+FY A +  A+ YLH   IVYRDLKPEN++LD +G+  +TDFG  K+ I     T TFCGTPEY+APE++    +D + D+W LG +++E+L G PPF + +  + Y  IL   + +++    +  A ++++ L   +P +RLG     ILE++ HV+F   NWN L  + I  P  P V    D  NFD
Sbjct:   85 LQAKPSDFDFLTVLGKGSFGKVLLAKHKSD-GIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILH--QPLQLRPCTTNAAISVLEGLLHKDPHQRLG-ATSDILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFD 380
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 249.21 bits (635), Expect = 5.616e-76
Identity = 124/302 (41.06%), Postives = 194/302 (64.24%), Query Frame = 3 
Query: 1278 LKDLCFVATIGIGGFGRVELVQ-IGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAI-DHSNFDSYPPDE 2177
            L D   + T+G G FGRV LV+ + N R   +A+K LKK  +V+ +Q EH  +E+R+L+ V+  F+++++ TF+D + ++M+M+   GGE++++LR    F +  A+FY A V++AL+YLH   I+YRDLKPEN++LD  G+ KITDFGF+K++  +  TWT CGTP+Y+APE+I  K ++ S D+WSLG+L++E+L G  PF  + PMKTY  IL+G   +  P     +  +L+ KL   +   R+G  + G  +++ H WF    W  L+ + I+ P  P + S I D S FD YP ++
Sbjct:   67 LHDFQIMRTLGTGSFGRVHLVRSVHNGRY--YAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTV--TWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQG--KVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQ 362
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 248.825 bits (634), Expect = 9.953e-76
Identity = 127/301 (42.19%), Postives = 191/301 (63.46%), Query Frame = 3 
Query: 1278 LKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAI-DHSNFDSYPPDE 2177
            L D   + T+G G FGRV L++  N   + +ALK LKK+ IV+ +Q EH  +E+R+L  V   FI++++ TF+D + ++M+M+   GGE++++LR    F +  A+FY A V +AL+YLH K I+YRDLKPEN++LD  G+ KITDFGF+K +  +  T+T CGTP+Y+APE++  K ++ S D+WS G+L++E+L G  PF  S+ MKTY  IL     ++ P     +A +L+KKL   +  ERLG  + G  +V+ H WF    W  L+ R I+ P  P ++    D S FD YP +E
Sbjct:   85 LSDFQILRTLGTGSFGRVHLIR-SNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--TYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNA--ELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEE 380
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 235.343 bits (599), Expect = 1.195e-70
Identity = 121/303 (39.93%), Postives = 192/303 (63.37%), Query Frame = 3 
Query: 1278 LKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAI-DHSNFDSYPPDEDV 2183
            L+D   + T+G G FGRV L++  ++  + +A+K LKK  +V  +Q EH  +E+ +L  V   FI++++ TF+D + ++M+M+   GGE++++LR    F +  A+FY A V +AL+YLH K I+YRDLKPEN++LD  G+ KITDFGF+K +  +  T+T CGTP+Y+APE++  K ++ S D+WS GIL++E+L G  PF  S+ MKTY  IL     +  P   +++  +L+ +L   +  +RLG  + G  +V+ H WF+   W  L+ R I+ P  P ++    D S FD Y P+ED+
Sbjct:   84 LQDFQILRTLGTGSFGRVHLIRSRHN-GRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDV--TYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNA--ELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKY-PEEDI 380
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 213.772 bits (543), Expect = 4.690e-60
Identity = 117/297 (39.39%), Postives = 176/297 (59.26%), Query Frame = 3 
Query: 1272 LQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSK-KIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFD 2159
            L + D   +  IG G FG+V  V+   D  + +ALK ++K +IV   +  H + E+ +L  VD  FIV L  +F+  + LY ++    GGE++  L+    FD   ARFYTA ++ ALD LH+  +VYRDLKPEN++LD +G+  + DFG  K  +    KT TFCGTPEY+APE++L  G+  + D+W+LG+L++E+LTG PP+   D  K Y  IL+  E +  P    ++A +L+  L   +P  RLGY   G  E++ H +F   +W  L+ +   PP  P V +++D SNFD
Sbjct:  342 LSIDDFDLLKVIGKGSFGKVMQVR-KKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQ--EPLVFPDGFDRDAKDLLIGLLSRDPTRRLGY--NGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFD 633
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 201.83 bits (512), Expect = 7.559e-56
Identity = 113/297 (38.05%), Postives = 173/297 (58.25%), Query Frame = 3 
Query: 1272 LQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSK-KIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFD 2159
            L + D   +  IG G FG+V  V+   D  + +ALK L+K +IV   +  H + E+ +L  VD  FIV L  +F+  + LY+++    GGE++  L+    F    +RFY A ++ ALD LH+  ++YRDLKPEN++LD +G+  + DFG  K  +    KT TFCGTPEY+APEI+L +G+  + D+W+LGIL++E++TG PP+   +    Y  IL+  + +  P      A +L+  L   +P  RLG    G  E++ H +F+  +W  L+ +   PP  P VKS ID +NFD
Sbjct:  339 LSIDDFDLLKVIGKGSFGKVMQVR-KKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQ--QPLLFPDGFDPAAKDLLIGLLSRDPSRRLGVN--GTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFD 630
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7])

HSP 1 Score: 697.197 bits (1798), Expect = 0.000e+0
Identity = 365/667 (54.72%), Postives = 480/667 (71.96%), Query Frame = 3 
Query:  285 LLETIQIKNEQIAELEKDLKYFKNI--------PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI--------------FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            L + ++ K+E I  LE +L  ++++        P    +   +  GISAEP+      DS +K L    K  ++KE +  AIL+NDF+++L A+Q+ ++VE M       + +II+E E GS +Y LE+G  ++T +G  L  M  G  FGELAILYNCTRTASVRA+T  KLW IDR++FQ+IMMK+G+ R  E+++FL+SV   K+L    L+KIADV+ E  Y + +YIIR+GARGDTF+II  G V +T++   ++ +   +R L +G +FGEKALK ED+RTAN IA    GV CLVLDR+++   I +L +  RD  D    D QR +              F  ++L+DL  V T+GIGGFGRVELVQ+  D+ ++FALK LKK+HIVETRQQ+H+++EK+I+ E +S FIV+L+KTFKD+KYLYM++EVCLGGE+WTILRDR  FDD T RFY  CV+ A  YLH KGIVYRDLKPENL+LD  GYCK+ DFGF+KKIGF RKTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILM+ELLTG+PPFS +DPMKTYNIILKGI+ I+ P  +++NA+ LIKKL RDNP+ERLGY K G+ ++ KH WF+GFNW+GL  R +  PI PK+KS +D SNFD YP D+D+PPDD++GWD +F
Sbjct:    3 LEQELRRKDELIRRLESELDKYRSVLQPPASAGPGGRSRARNQRQGISAEPQSAKQVADS-SKPLQRHPKNSRSKELIKEAILDNDFLKNLEASQVREVVECMCERMFKRDEYIIKEKEPGSHLYVLEEGKCQVTKEGTVLGHMGPGKAFGELAILYNCTRTASVRAQTSGKLWAIDRQTFQTIMMKTGLMRTAEHMEFLRSVNLLKDLAESYLLKIADVIEETFYEEGEYIIRQGARGDTFFIIKSGNVDITQRTNVHS-DPVHVRNLSKGAYFGEKALKGEDLRTANCIA-GKGGVTCLVLDREAFVQFIGNLDDIQRDQYD----DSQRGVDPQTASHLRAQQDEFANVRLEDLTVVKTLGIGGFGRVELVQVAGDK-RTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSPVDASNFDDYPADDDIPPDDMTGWDKDF 661
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8])

HSP 1 Score: 630.172 bits (1624), Expect = 0.000e+0
Identity = 333/655 (50.84%), Postives = 442/655 (67.48%), Query Frame = 3 
Query:  360 PVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFN-RDYEDEK--------LSDKQRSI---FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPP-----------------------IIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            P K +K++     +S E            K L    K+ ++K+ +  AI ENDF+++L A Q+ ++V+ MY  T   N  IIQEG+ G+ +YA+ DG +++T + + L +M  G +FGELAILYNC RTA+V A    KLW IDR  FQ IMM++G+ RQ E++ FL+SVP  KEL   +L K+ADVL  + Y+  DYIIRE  RGDTFYII+KG  +VT++       +  IR L +G +FGEKAL  ED RTAN+IA + +GV+CLV+DR  +  +I ++     +DY DEK        + +++R +   F  L L+DL  VAT+G GGFGRVELV        ++ALK LKK HI++TRQQEHV +EKRIL E +S FI K+Y+TFKDRKY+YM++E CLGGE+WTILRDR  F+D TARF  ACVV   +YLH KGIVYRDLKPENL+LD+KGY K+ DFGF+KKIG  RKTWTFCGTPEYVAPEIILNKGHD S+D+WSLGIL+FELLTG+PPFS+SDPMKTYNIIL+G++ +E P  + +N  NLIK+L +DNP+ERLGY K G+ +++KH +     W  L     + P                       ++ +V+S+ D+SNFD Y  D D+PPD++SGWD  F
Sbjct:   16 PSKKEKRQ----AVSGESSTKAQEESRTGKELERFPKDFRSKQLIKDAIFENDFLKNLEAAQVREIVDCMYSNTFQRNDVIIQEGDAGNALYAIADGRLQVTRENKVLGEMVAGMVFGELAILYNCRRTATVTAMEPTKLWKIDRRVFQIIMMRTGMIRQAEHMAFLKSVPLLKELPNAELSKLADVLEVDFYHAGDYIIRENERGDTFYIITKGSARVTQRIEGQTGPKE-IRKLQKGDYFGEKALLSEDRRTANVIA-EENGVECLVVDRTVFMTVIGNMDELREKDYGDEKRGAKRTLDVPEEERKVSKEFADLTLEDLEVVATLGTGGFGRVELV--------TYALKCLKKKHILDTRQQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKHKYV--VPWFPLAGTHRRDPRTSNQTRFWLMTTTLSFKTSPIYLLIRVESSTDYSNFDVYSKDMDIPPDEMSGWDENF 654
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62])

HSP 1 Score: 256.914 bits (655), Expect = 3.169e-79
Identity = 138/309 (44.66%), Postives = 194/309 (62.78%), Query Frame = 3 
Query: 1278 LKDLCFVATIGIGGFGRVELVQIGNDR--SQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTM-SKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDE--DVPP 2189
            L+D     T+G G FGRV L +   DR   + +ALK +    ++  +Q EHV NEK IL  ++  FIV L  T  D+ +LYM++E   GGE++T LR    F++ T  F+ + +V A+DYLH   IVYRDLKPEN++LD  G+ K+TDFGF+K++    KTWT CGTPEY+APEII +KGH+ + D+W+LGIL++E+L G PPF   +P   Y  IL G   +E P  M + +A +LIKKL   +   RLG  K G  +V+ H WF+  +WN ++ R ++PPI PK+    D  NFD YP ++    PP
Sbjct:   15 LQDFELSKTLGTGTFGRVLLAR---DRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVH--DKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSG--KVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGAPP 316
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Match: EDO31895 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWM6])

HSP 1 Score: 228.409 bits (581), Expect = 1.248e-65
Identity = 124/307 (40.39%), Postives = 186/307 (60.59%), Query Frame = 3 
Query: 1293 FVATIGIGGFGRVELVQ--IGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDS-----YPPDED-VPP 2189
             +  +G G FG+V LV+  IG D    +A+K LKK   ++ R +   + E+ IL +V   FIV+L   F+    +Y++++   GG+++T L    +F +   +FY A + +ALD+LH  GI+YRDLKPEN++LD+ G+  +TDFG SK+    +KT++FCGT EY+APE++  +GH  +AD+WS G+LMFE+LTG+ PF   D   T N+ILK    + +P  ++  A +L+++L + NPL RLG G  GI +++KH +F   NW  L  R I+PP  P    A D   FD       P D   VPP
Sbjct:   11 LLKVLGQGSFGKVFLVRKVIGADAGTLYAMKVLKK-ATLKVRDRMRTMKERDILVDVQHPFIVRLNYAFQTEGKVYLILDFLRGGDLFTRLSKEIMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDASGHVALTDFGLSKESEHDQKTYSFCGTVEYMAPEVVNRRGHSQAADWWSYGVLMFEMLTGSLPFQGKDRKDTMNMILKA--KLGMPQFLTPEAQSLLRQLFKRNPLNRLGAGDLGIEDIKKHPFFSTINWELLYKREIKPPFKPAAGRADDAFYFDPEFTSKTPQDSPAVPP 314

HSP 2 Score: 95.1301 bits (235), Expect = 2.414e-20
Identity = 56/162 (34.57%), Postives = 91/162 (56.17%), Query Frame = 3 
Query: 1470 IVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLI-LDSKG---YCKITDFGFSKKI----GFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGI 1931
            IV L   ++  K +Y++ME+  GGE+   +       +  A      +   + +LH +G+V+RDLKP N++  D  G     +I DFGF+K++    G L    T C T  +VAPE++  +G+D + D WSLG+L++ +L+G  PF+   P  T ++ILK I
Sbjct:  410 IVHLRDAYEAGKQVYIVMELMRGGELLDRILKHKCLSEREAGNIMYTLTSTIAFLHEEGVVHRDLKPSNIMYADDSGTPESLRIVDFGFAKQMRATNGLL---MTPCYTANFVAPEVLKKQGYDAACDIWSLGVLLYTMLSGLTPFAVG-PEDTPSVILKRI 567
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521])

HSP 1 Score: 219.164 bits (557), Expect = 6.462e-64
Identity = 119/294 (40.48%), Postives = 178/294 (60.54%), Query Frame = 3 
Query: 1293 FVATIGIGGFGRVELVQI--GNDRSQSFALKKLKKYHIVETRQQ-EHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRK-TWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDS 2162
             +  +G GG+G+V LV+   G+ + + FA+K LKK  I+ +++   H   E+ ILE V   FIV L   F+    LY+++E   GGE++  L    +F + TA FY + + MAL++LH++GIVYRDLKPEN++LD+ G+ K+TDFG  K+  F    T TFCGT EY+APEI+   GH  + D+WSLG LM+++LTGTPPF   +  KT + ILKG   + +P  ++  A + I+KL + +P  RLG        ++ H +F    W  L+ + ++PP  P +    D S FDS
Sbjct:   67 LLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKG--KLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFDS 358
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Match: prkg1 (protein kinase cGMP-dependent 1 [Source:NCBI gene;Acc:100049290])

HSP 1 Score: 733.021 bits (1891), Expect = 0.000e+0
Identity = 379/683 (55.49%), Postives = 488/683 (71.45%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQ---------KKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDYEDEKLS-DKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I  L+ +L  ++++  P   Q         ++  +   ISAEP   +       + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY+ FL+SVPTF +LQ + L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV VT++   N E   ++R L +G WFGEKAL+ ED+RTA++IA +   V CLV+DRDS+  LI    D+ +   D  D K   + + + F  L L D   + T+G+GGFGRVELVQ+ +D +++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILMFELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S +D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQRLQNELDKYRSVIKPATQQVHKQNELHEQQRTKRQAISAEPTAFDI------QDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKENLKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMDFLKSVPTFHDLQEDILSKLADVLEETHYAGGEYIIRQGARGDTFFIISKGKVNVTREDLPNGE-PVYLRSLGKGDWFGEKALQGEDIRTASVIAAE--AVTCLVIDRDSFKHLIGGLEDVSSKGHDDADAKAKYEAENAFFFSLNLADFNIIDTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPCERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPNVTSPVDTSNFDSFPEDNEDPPPDDNSGWDVDF 684
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Match: prkg1 (protein kinase cGMP-dependent 1 [Source:NCBI gene;Acc:100049290])

HSP 1 Score: 698.353 bits (1801), Expect = 0.000e+0
Identity = 359/638 (56.27%), Postives = 462/638 (72.41%), Query Frame = 3 
Query:  237 DEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQ---KKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDYEDEKLS-DKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKV 2129
            ++F   L  KE  I+ L   +  + ++I EL++ L   +++    Q    +  R  GISAEP+    + D   + L    K   +K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY+ FL+SVPTF +LQ + L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV VT++   N E   ++R L +G WFGEKAL+ ED+RTA++IA +   V CLV+DRDS+  LI    D+ +   D  D K   + + + F  L L D   + T+G+GGFGRVELVQ+ +D +++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILMFELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V
Sbjct:    6 EDFAKILLLKEERIRDLERRLADREDEIQELKRKLHKCQSVLPSAQLIGPRTRRAQGISAEPQT---HQDLSRQALRRYPKSDWSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKENLKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMDFLKSVPTFHDLQEDILSKLADVLEETHYAGGEYIIRQGARGDTFFIISKGKVNVTREDLPNGE-PVYLRSLGKGDWFGEKALQGEDIRTASVIAAE--AVTCLVIDRDSFKHLIGGLEDVSSKGHDDADAKAKYEAENAFFFSLNLADFNIIDTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPCERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPNV 637
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Match: prkg1 (protein kinase cGMP-dependent 1 [Source:NCBI gene;Acc:100049290])

HSP 1 Score: 692.575 bits (1786), Expect = 0.000e+0
Identity = 359/652 (55.06%), Postives = 465/652 (71.32%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQ---------KKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDYEDEKLS-DKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKV 2129
            L E   +L +++  I  L   +  K+E I  L+ +L  ++++  P   Q         ++  +   ISAEP   +       + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY+ FL+SVPTF +LQ + L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV VT++   N E   ++R L +G WFGEKAL+ ED+RTA++IA +   V CLV+DRDS+  LI    D+ +   D  D K   + + + F  L L D   + T+G+GGFGRVELVQ+ +D +++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR  F+D T RFYTACVV A  YLH KGI+YRDLKPENLILD +GY K+ DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILMFELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQRLQNELDKYRSVIKPATQQVHKQNELHEQQRTKRQAISAEPTAFDI------QDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKENLKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMDFLKSVPTFHDLQEDILSKLADVLEETHYAGGEYIIRQGARGDTFFIISKGKVNVTREDLPNGE-PVYLRSLGKGDWFGEKALQGEDIRTASVIAAE--AVTCLVIDRDSFKHLIGGLEDVSSKGHDDADAKAKYEAENAFFFSLNLADFNIIDTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPCERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPNV 653
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Match: prkg1 (protein kinase cGMP-dependent 1 [Source:NCBI gene;Acc:100049290])

HSP 1 Score: 652.514 bits (1682), Expect = 0.000e+0
Identity = 351/683 (51.39%), Postives = 461/683 (67.50%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNI--PVKLQ---------KKEVRGIGISAEPRGLNFNYDSLAKGLNHVA-----KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLI---RDLVNFNRDYEDEKLS-DKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPD-EDVPPDDISGWDNEF 2219
            L E   +L +++  I  L   +  K+E I  L+ +L  ++++  P   Q         ++  +   ISAEP   +       + L+HV      K  ++K+ +  AIL+NDFM++L  +QI ++V+ MYPV    +S II+EG++GS+VY +EDG VE+T +  KL  M  G +FGELAILYNCTRTA+V+  T  KLW IDR+ FQ+IMM++G+ +  EY+ FL+SVPTF +LQ + L K+ADVL E HY   +YIIR+GARGDTF+IISKGKV VT++   N E   ++R L +G WFGEKAL+ ED+RTA++IA +   V CLV+DRDS+  LI    D+ +   D  D K   + + + F  L L D   + T+G+GGFGRVELVQ+ +D +++FA+K LKK HIV+TRQQEH+ +EK I++E  S+FIV+LY+TFKD KYLYM+ME CLGGE+WTILRDR     +    +         ++  KG        +NLI          DFGF+KKIGF +KTWTFCGTPEYVAPEIILNKGHD SAD+WSLGILMFELLTG+PPFS  DPMKTYNIIL+GI+ IE P  ++KNA NLIKKL RDNP ERLG  K G+ ++QKH WFEGFNW GL    + PPIIP V S +D SNFDS+P D ED PPDD SGWD +F
Sbjct:   11 LQEKIEELRQRDALIDELELELDQKDELIQRLQNELDKYRSVIKPATQQVHKQNELHEQQRTKRQAISAEPTAFDI------QDLSHVTLPFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKENLKLCTMGPGKVFGELAILYNCTRTATVKTLTNVKLWAIDRQCFQTIMMRTGLIKHTEYMDFLKSVPTFHDLQEDILSKLADVLEETHYAGGEYIIRQGARGDTFFIISKGKVNVTREDLPNGE-PVYLRSLGKGDWFGEKALQGEDIRTASVIAAE--AVTCLVIDRDSFKHLIGGLEDVSSKGHDDADAKAKYEAENAFFFSLNLADFNIIDTLGVGGFGRVELVQLKSDENKTFAMKILKKRHIVDTRQQEHIRSEKLIMQEAHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRHKSFKINTHIWIGRCCFMFTFICIKGHSCPTPDQKNLIFLQ------VDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGHDISADYWSLGILMFELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKITKNAGNLIKKLCRDNPCERLGNLKNGVKDIQKHKWFEGFNWEGLKKGTLTPPIIPNVTSPVDTSNFDSFPEDNEDPPPDDNSGWDVDF 678
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Match: prkg2 (protein kinase cGMP-dependent 2 [Source:NCBI gene;Acc:101158535])

HSP 1 Score: 617.461 bits (1591), Expect = 0.000e+0
Identity = 322/641 (50.23%), Postives = 429/641 (66.93%), Query Frame = 3 
Query:  396 GISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNR------------DYEDEK------LSDKQRSIFN--YLQLKDLC-------------FVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            G+SAEP   +    S  K    V K+   K+ L  A+ +N ++R L   QI D+VE MY         +I++GE G+ ++ L +G +E+    + L  +T  + FGELAILYNCTRTASVRA  K K W +DRE+FQ+IM ++   R E+Y  FL+SV     L  +KL KI D L   +Y+K +YIIREG  G TFYII++GKVKVT+    +   +  I  L +G +FGEKAL  +DVR+ANIIA D +GV+CLV+DR++++   + + NFN             D +D+K      +S  Q    +  ++QLKD+               +AT+G+GGFGRVELV++  +   +FALK +KK H+VE +Q+EH+ +E+RIL E  S FIV+LY+TFKD KY+YM++E CLGGEVW++LRDR  FDD TA+F   CV  A +YLHRKG++YRDLKPENL+LD +GY K+ DFGF+KKI   +KTWTFCGTPEYVAPEIILNKGH+FS DFW+LGIL+FELLTG+PPFS SD M  Y  ILKGIE ++ P  +SK   +LI+KL R NP ERLG  K GI +++KH WF GFNW GL  R +  P+  ++K  +DHS FDSYPPDED PPD++SGWD +F
Sbjct:  137 GVSAEPTSSSLQKFSFEKA--RVPKDASVKKLLTDALNKNQYLRRLELQQIKDMVECMYERNYQQGECVIKQGEPGNHLFVLAEGKLEVFQHNKLLTWITVWTTFGELAILYNCTRTASVRAVNKVKTWALDREAFQNIMRRTAETRHEQYRNFLRSVSLLANLPDDKLSKIVDCLEVEYYDKGEYIIREGEEGSTFYIIAQGKVKVTQTTEAHKLPQ-IINALQKGDYFGEKALVSDDVRSANIIA-DDNGVECLVIDRETFD---QTVGNFNELQKHLQGYVASLDRDDKKRHLKKSVSRHQSQSLSPGFMQLKDMVSLFTSSRPFHHLEVIATLGVGGFGRVELVKVKGE-DVTFALKAIKKKHVVENKQEEHIHSERRILAEARSPFIVRLYRTFKDSKYVYMLLEACLGGEVWSLLRDRGSFDDPTAKFCIGCVTEAFEYLHRKGVLYRDLKPENLLLDMEGYVKLVDFGFAKKIRSGQKTWTFCGTPEYVAPEIILNKGHNFSVDFWALGILVFELLTGSPPFSGSDQMTIYTFILKGIEKMDFPKMISKRPEDLIRKLCRRNPSERLGNLKNGITDIKKHRWFTGFNWEGLKARTLASPLKRELKGPMDHSYFDSYPPDEDSPPDELSGWDEDF 769
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Match: SMESG000018148.1 (SMESG000018148.1)

HSP 1 Score: 868.226 bits (2242), Expect = 0.000e+0
Identity = 460/464 (99.14%), Postives = 461/464 (99.35%), Query Frame = 3 
Query:  168 MNSQSVXXXXXXXXXXXXXXXXLDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTIL 1559
            MNSQSVESNNNSTKNNETTCKELDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISKGKVKVTKKCGKNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGE+   L
Sbjct:    1 MNSQSVESNNNSTKNNETTCKELDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISKGKVKVTKKCGKNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEILHCL 464

HSP 2 Score: 57.3806 bits (137), Expect = 3.154e-8
Identity = 25/26 (96.15%), Postives = 26/26 (100.00%), Query Frame = 2 
Query: 1592 QILHCLCRYGFRLFAQKRNSLSGLKA 1669
            +ILHCLCRYGFRLFAQKRNSLSGLKA
Sbjct:  459 EILHCLCRYGFRLFAQKRNSLSGLKA 484
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Match: SMESG000005347.1 (SMESG000005347.1)

HSP 1 Score: 867.07 bits (2239), Expect = 0.000e+0
Identity = 409/589 (69.44%), Postives = 494/589 (83.87%), Query Frame = 3 
Query:  453 LNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +  V K  K+KE +  AI +ND+M+HL  +QI+++VE M PVT    SWIIQEGEIGS+VYALEDG+VE+T  G  +R+M  G++FGELAILYNCTRTASVRA T+CKLW IDR+ FQSIMMK+G+R+QE+Y++FL+SVPTF+++ ME L KIA VLGENHY++ DYIIREG +G TFYII KG+VKVTKK  K++E E FIR+LDRG WFGEKAL+DEDVRTA+IIA    GVDCLVLDR+SYNLLI D+VNF++ Y DE  + ++ S F  L L+DLC + T+G+GGFGRVELV+IGND  ++FALK LKKYHIVET QQEHV+NE+ IL EVDSEFIVKLYKTFKDR+YLYM+MEVCLGGEVWTILR++  FDD T +FYTA V++AL+YLHRKGIV+RDLKPEN +LD KGYCK+TDFGF+KKIGF RKTWTFCGTPEYVAPEIILNKGHDF+ D WSLGILM+EL TGTPPF++SDPMKTYNIILKGI+ I+    +SK+A +LIKKL R+NP ERLGYGK G+ E QKH WFEGFNW GL+ +  +PPIIP+VKSA+D SNFD Y PDE+ P +DISGWD +F
Sbjct:  272 MKRVEKPSKSKELIRSAIYDNDYMKHLDPSQITEIVECMSPVTYHEGSWIIQEGEIGSIVYALEDGLVEVTKSGAIIREMGPGTVFGELAILYNCTRTASVRATTECKLWAIDRQCFQSIMMKTGLRKQEDYIRFLKSVPTFQDMNMETLGKIAGVLGENHYSQGDYIIREGEKGATFYIIEKGRVKVTKKTSKSDE-EVFIRHLDRGSWFGEKALRDEDVRTASIIAESPSGVDCLVLDRESYNLLIGDIVNFDKQYPDEDKARRRASKFPELALRDLCVITTLGVGGFGRVELVRIGNDDRRTFALKVLKKYHIVETHQQEHVMNERDILMEVDSEFIVKLYKTFKDRRYLYMLMEVCLGGEVWTILREKVSFDDATTKFYTASVILALEYLHRKGIVFRDLKPENCLLDEKGYCKLTDFGFAKKIGFARKTWTFCGTPEYVAPEIILNKGHDFAVDIWSLGILMYELFTGTPPFTSSDPMKTYNIILKGIQTIDFSSKISKHAQSLIKKLCRENPSERLGYGKLGVAEAQKHAWFEGFNWEGLLSKKTKPPIIPQVKSAVDVSNFDLYSPDEETPAEDISGWDKDF 859
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Match: SMESG000016927.1 (SMESG000016927.1)

HSP 1 Score: 815.453 bits (2105), Expect = 0.000e+0
Identity = 405/683 (59.30%), Postives = 518/683 (75.84%), Query Frame = 3 
Query:  234 LDEFKNKLAKKEIEIKRLLETIQIKNEQIAELEKDLKYFKNIPVKLQKK------------EVRGIGISAEPRGLNF-NYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNN--ENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI------FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            +++ + +L KK+  +K+L + +Q K+E+IAEL   L  ++++    QK+             VRG+GISAEP+     N+       +   K+ KTKE + R+ILENDFM++L  +QI  +V+ M PV   +NS II+EGE+GS+VY +EDG V ++ +G  LR+M   ++FGELAILYNCTRTA+V A T CKLW IDR SFQSIMM++G+ + EE + FL+SVP FK+L+   L KI+ VL E HY   DYIIR+G +GDTF+IIS GKV+VT+K   ++  E E FIR + RG+WFGEKALKDED+RTANIIA D  GVDCLVLDR+SY  LI DL +  R YED  ++D  + I      +  L LKDL  +AT+GIGGFGRVELVQIG++  +++ALK+LKK+HIVETRQQEH++NE+ IL  V S+FIV+L++TFKDRK+LYM+MEVCLGGE+W+ILRDR+ FD+ T +FYTACV+ AL YLH +GIVYRDLKPENL+LD++G+CKITDFGF+KKIGF RKTWTFCGTPEYVAPEIILNKGHD  AD WSLGILMFELLTG PPF+  DPMK YNIILKGI+AIE P  +SK+A NLIKKL RDNP ER+GYGK G+ E QKH+W E FNW+GL+   I+PPI+P++ S  D SNFD YPP+ ++PPDDISGWD +F
Sbjct:    5 INQLQQELIKKDEYVKKLEKLLQQKDEKIAELTSQLDKYQSVFSATQKQNNVQSGPHNNQTRVRGLGISAEPQTAKIANFQP-----SFFQKDSKTKELIKRSILENDFMKNLEQSQIKMIVDCMRPVKFAANSIIIKEGEVGSLVYVMEDGKVSVSKEGHHLREMKNETVFGELAILYNCTRTATVTAITDCKLWAIDRHSFQSIMMRTGLLKYEENLNFLKSVPIFKDLEESTLGKISGVLEETHYANGDYIIRQGTKGDTFFIISSGKVQVTRKNKPDDTKEKEQFIRQMQRGEWFGEKALKDEDLRTANIIAADPAGVDCLVLDRESYIQLIGDLTSLQRTYED-GVNDSPKEILGPSKEYKNLALKDLVVIATLGIGGFGRVELVQIGDNAKKTYALKQLKKHHIVETRQQEHIMNERNILYMVQSDFIVRLHRTFKDRKFLYMLMEVCLGGELWSILRDRSAFDENTTKFYTACVIEALHYLHSRGIVYRDLKPENLLLDNQGFCKITDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDTYADCWSLGILMFELLTGMPPFTAPDPMKIYNIILKGIDAIEFPKKISKDAQNLIKKLCRDNPNERVGYGKGGVKECQKHLWLESFNWDGLLSHTIKPPIVPQINSPTDCSNFDEYPPETEMPPDDISGWDRDF 681
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Match: SMESG000016927.1 (SMESG000016927.1)

HSP 1 Score: 793.497 bits (2048), Expect = 0.000e+0
Identity = 390/631 (61.81%), Postives = 488/631 (77.34%), Query Frame = 3 
Query:  351 KNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVAKEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNN--ENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFNRDYEDEKLSDKQRSI------FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEF 2219
            KN   KL  + ++ I IS E    +  + S  + L +  K  KTKE + R+ILENDFM++L  +QI  +V+ M PV   +NS II+EGE+GS+VY +EDG V ++ +G  LR+M   ++FGELAILYNCTRTA+V A T CKLW IDR SFQSIMM++G+ + EE + FL+SVP FK+L+   L KI+ VL E HY   DYIIR+G +GDTF+IIS GKV+VT+K   ++  E E FIR + RG+WFGEKALKDED+RTANIIA D  GVDCLVLDR+SY  LI DL +  R YED  ++D  + I      +  L LKDL  +AT+GIGGFGRVELVQIG++  +++ALK+LKK+HIVETRQQEH++NE+ IL  V S+FIV+L++TFKDRK+LYM+MEVCLGGE+W+ILRDR+ FD+ T +FYTACV+ AL YLH +GIVYRDLKPENL+LD++G+CKITDFGF+KKIGF RKTWTFCGTPEYVAPEIILNKGHD  AD WSLGILMFELLTG PPF+  DPMK YNIILKGI+AIE P  +SK+A NLIKKL RDNP ER+GYGK G+ E QKH+W E FNW+GL+   I+PPI+P++ S  D SNFD YPP+ ++PPDDISGWD +F
Sbjct:  169 KNGDFKLSNERMKRIAISGE----SGTFISSPEVLPYFEKHLKTKELIKRSILENDFMKNLEQSQIKMIVDCMRPVKFAANSIIIKEGEVGSLVYVMEDGKVSVSKEGHHLREMKNETVFGELAILYNCTRTATVTAITDCKLWAIDRHSFQSIMMRTGLLKYEENLNFLKSVPIFKDLEESTLGKISGVLEETHYANGDYIIRQGTKGDTFFIISSGKVQVTRKNKPDDTKEKEQFIRQMQRGEWFGEKALKDEDLRTANIIAADPAGVDCLVLDRESYIQLIGDLTSLQRTYED-GVNDSPKEILGPSKEYKNLALKDLVVIATLGIGGFGRVELVQIGDNAKKTYALKQLKKHHIVETRQQEHIMNERNILYMVQSDFIVRLHRTFKDRKFLYMLMEVCLGGELWSILRDRSAFDENTTKFYTACVIEALHYLHSRGIVYRDLKPENLLLDNQGFCKITDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDTYADCWSLGILMFELLTGMPPFTAPDPMKIYNIILKGIDAIEFPKKISKDAQNLIKKLCRDNPNERVGYGKGGVKECQKHLWLESFNWDGLLSHTIKPPIVPQINSPTDCSNFDEYPPETEMPPDDISGWDRDF 794
[Close]
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Match: SMESG000074822.1 (SMESG000074822.1)

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 290/588 (49.32%), Postives = 395/588 (67.18%), Query Frame = 3 
Query:  510 ENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGEIGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKTKCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIADVLGENHYNKDDYIIREGARGDTFYIISXXXXXXXXXXXXNNENETFIRYLDRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFN-RDYEDEKLSDKQRSI----------------FNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQSFALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYMMMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLKPENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHDFSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKNAYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPIIPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEFE 2222
            ++DF++ L   QI  + + MY  T+ +N +IIQEGE G  +Y L  G +E+   G+KLR M  G +FGELA+L NC RTASV+A T+   WTI+R+ +Q+I+ KS +++ EEY KFLQSV  FK L  ++L KI D L    Y+  +YI++EG  G TFYII  GKVKV +      E +  IR L  G +FGE+AL  E++RTA++IA D D V+ L+LDR+ +  LI      N ++YED K+  +Q S                 +  +Q  DL  ++T+G+GGFG+VELV+  ND S  FALK L K +IVE +Q+EH+I+E++IL E+   FI +LYKTF+D KY+Y++ME CLGGE+WT LR++TVFDD   +F     ++A+ YLH K I+YRDLKPEN++ D++G+ K+ DFGF+K IG  RKT+TFCGTPEYVAPEIILNKGHD S D W++GIL FELLTG+PPF   +PM  YN ILKG+E +E    +++ A  LIK L +DNP ERLGYGK GI  +  H +F GFNW  L+ + + P IIPK+++ ID   FD +     VP D+ SGWD+EFE
Sbjct:  193 QDDFLKKLEQQQIKQICQCMYSKTVKANVYIIQEGEPGYHMYVLASGKMEVIKDGKKLRDMYPGELFGELAVLQNCLRTASVKAVTEASFWTIERKVYQAILQKSNMQQSEEYKKFLQSVNLFKSLSKDELTKIVDALLMEEYSLGEYIVQEGEEGQTFYIIKNGKVKVVQNVQGVVEPQE-IRTLTTGDYFGERALLKEEIRTASVIA-DSDNVEVLLLDREDFIRLIGQNYELNSKEYEDYKIKKQQSSTIPIESTKKDNIIIKNKYQIIQKNDLEVISTLGVGGFGKVELVRHKNDHSMVFALKSLSKQYIVELKQEEHIISERKILLEIKFPFICELYKTFRDNKYVYLLMEACLGGEIWTHLRNKTVFDDRMTKFILGSSILAIQYLHSKNIIYRDLKPENMVFDNRGFVKLCDFGFAKLIGNGRKTFTFCGTPEYVAPEIILNKGHDASVDIWAIGILAFELLTGSPPFVGDEPMIVYNKILKGVEKVEFGRKINRTAVQLIKMLCKDNPTERLGYGKDGISAIMNHKYFTGFNWEALLSKEMTPVIIPKLENNIDTHYFDQFTEKNFVPLDETSGWDDEFE 778
The following BLAST results are available for this feature:
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRKG10.000e+057.16protein kinase cGMP-dependent 1 [Source:HGNC Symbo... [more]
PRKG10.000e+055.67protein kinase cGMP-dependent 1 [Source:HGNC Symbo... [more]
PRKG20.000e+047.78protein kinase cGMP-dependent 2 [Source:HGNC Symbo... [more]
PRKG20.000e+047.78protein kinase cGMP-dependent 2 [Source:HGNC Symbo... [more]
PRKG20.000e+047.64protein kinase cGMP-dependent 2 [Source:HGNC Symbo... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
egl-40.000e+049.30cGMP-dependent protein kinase egl-4 [Source:UniPr... [more]
egl-40.000e+049.30cGMP-dependent protein kinase egl-4 [Source:UniPr... [more]
egl-40.000e+049.30cGMP-dependent protein kinase egl-4 [Source:UniPr... [more]
egl-40.000e+049.30cGMP-dependent protein kinase egl-4 [Source:UniPr... [more]
egl-40.000e+049.30cGMP-dependent protein kinase egl-4 [Source:UniPr... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
for0.000e+052.62gene:FBgn0000721 transcript:FBtr0089310[more]
for0.000e+052.62gene:FBgn0000721 transcript:FBtr0089312[more]
for0.000e+052.62gene:FBgn0000721 transcript:FBtr0089304[more]
for0.000e+052.62gene:FBgn0000721 transcript:FBtr0446099[more]
for0.000e+059.58gene:FBgn0000721 transcript:FBtr0473363[more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkg1b0.000e+057.42protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:... [more]
prkg1b0.000e+055.64protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:... [more]
prkg1a0.000e+056.87protein kinase cGMP-dependent 1a [Source:ZFIN;Acc:... [more]
prkg1b0.000e+054.27protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:... [more]
prkg20.000e+043.64protein kinase cGMP-dependent 2 [Source:ZFIN;Acc:Z... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
camk40.000e+056.93calcium/calmodulin-dependent protein kinase IV [So... [more]
camk40.000e+055.99calcium/calmodulin-dependent protein kinase IV [So... [more]
camk40.000e+055.99calcium/calmodulin-dependent protein kinase IV [So... [more]
ptafr0.000e+049.62platelet activating factor receptor [Source:Xenbas... [more]
tnpo20.000e+045.34transportin 2 [Source:Xenbase;Acc:XB-GENE-968452][more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prkg10.000e+057.16protein kinase, cGMP-dependent, type I [Source:MGI... [more]
Prkg10.000e+055.67protein kinase, cGMP-dependent, type I [Source:MGI... [more]
Prkg20.000e+047.57protein kinase, cGMP-dependent, type II [Source:MG... [more]
Prkg20.000e+047.42protein kinase, cGMP-dependent, type II [Source:MG... [more]
Prkg11.322e-15761.21protein kinase, cGMP-dependent, type I [Source:MGI... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P00516|KGP1_BOVIN0.000e+057.46cGMP-dependent protein kinase 1 OS=Bos taurus OX=9... [more]
sp|P0C605|KGP1_MOUSE0.000e+057.16cGMP-dependent protein kinase 1 OS=Mus musculus OX... [more]
sp|Q13976|KGP1_HUMAN0.000e+057.16cGMP-dependent protein kinase 1 OS=Homo sapiens OX... [more]
sp|O77676|KGP1_RABIT0.000e+056.87cGMP-dependent protein kinase 1 OS=Oryctolagus cun... [more]
sp|Q03043|KGP24_DROME0.000e+052.62cGMP-dependent protein kinase, isozyme 2 forms cD4... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
G4LX390.000e+066.78cGMP-dependent protein kinase,putative OS=Schistos... [more]
A0A267FPA90.000e+060.21cGMP-dependent protein kinase OS=Macrostomum ligna... [more]
A0A267GV060.000e+060.21cGMP-dependent protein kinase OS=Macrostomum ligna... [more]
A0A4E0RB430.000e+066.27cGMP-dependent protein kinase 1 OS=Fasciola hepati... [more]
A0A267FLY40.000e+058.74cGMP-dependent protein kinase OS=Macrostomum ligna... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkg1b0.000e+056.73protein kinase cGMP-dependent 1b [Source:ZFIN;Acc:... [more]
prkg1a0.000e+051.32protein kinase cGMP-dependent 1a [Source:ZFIN;Acc:... [more]
prkg20.000e+044.46protein kinase cGMP-dependent 2 [Source:NCBI gene;... [more]
ENSAMXT00000002114.20.000e+047.57cGMP-dependent protein kinase 2-like [Source:NCBI ... [more]
prkg20.000e+044.91protein kinase cGMP-dependent 2 [Source:NCBI gene;... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000002200.11.015e-12856.17pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 ... [more]
ENSPMAT00000002201.11.270e-10651.62pep scaffold:Pmarinus_7.0:GL479132:31244:36797:-1 ... [more]
ENSPMAT00000001814.15.315e-7441.54pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen... [more]
ENSPMAT00000008480.14.626e-5637.61pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1... [more]
ENSPMAT00000006766.11.143e-5536.67pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 g... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TPK25.616e-7641.06cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK39.953e-7642.19cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK11.195e-7039.93cAMP-dependent protein kinase catalytic subunit; p... [more]
YPK14.690e-6039.39S/T protein kinase; phosphorylates, downregulates ... [more]
YPK27.559e-5638.05Protein kinase similar to S/T protein kinase Ypk1p... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO384070.000e+054.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO383990.000e+050.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO352283.169e-7944.66Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO318951.248e-6540.39Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411666.462e-6440.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkg10.000e+055.49protein kinase cGMP-dependent 1 [Source:NCBI gene;... [more]
prkg10.000e+056.27protein kinase cGMP-dependent 1 [Source:NCBI gene;... [more]
prkg10.000e+055.06protein kinase cGMP-dependent 1 [Source:NCBI gene;... [more]
prkg10.000e+051.39protein kinase cGMP-dependent 1 [Source:NCBI gene;... [more]
prkg20.000e+050.23protein kinase cGMP-dependent 2 [Source:NCBI gene;... [more]
back to top
BLAST of cGMP-dependent protein kinase,putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000018148.13.154e-899.14SMESG000018148.1[more]
SMESG000005347.10.000e+069.44SMESG000005347.1[more]
SMESG000016927.10.000e+059.30SMESG000016927.1[more]
SMESG000016927.10.000e+061.81SMESG000016927.1[more]
SMESG000074822.10.000e+049.32SMESG000074822.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025573 ID=SMED30025573|Name=cGMP-dependent protein kinase,putative|organism=Schmidtea mediterranea sexual|type=transcript|length=2312bp
TGTTTCATTGGCTGGATTTCGACTAATAATATTTCAGTGCTCTTAAATTA
GCATCACAAAAAAATTCTTGTATTGAAATCTTATCCCTACTTTCAAATTT
AATTCTGGAATCATCAAATTCTTCAAGCTATTTTCCAAGAGTGTTTCGTG
GATTTTTGGAGGGTGTTATGAACTCACAAAGTGTCGAATCCAATAACAAT
TCAACCAAAAATAATGAAACCACTTGTAAGGAATTGGATGAATTCAAAAA
TAAATTAGCCAAAAAGGAAATTGAAATTAAAAGGCTGTTGGAAACAATCC
AAATAAAAAATGAACAAATAGCTGAATTAGAGAAAGATCTTAAATACTTC
AAAAATATTCCAGTAAAATTACAAAAGAAAGAGGTTAGAGGTATTGGAAT
ATCAGCTGAACCAAGAGGTCTAAATTTTAACTACGATTCCTTGGCAAAGG
GTTTGAATCATGTTGCTAAAGAAAAAAAAACAAAAGAATGTCTTGTTCGA
GCAATTTTGGAAAATGATTTTATGAGACATTTAAGTGCAAACCAAATATC
CGACTTAGTGGAAAATATGTATCCTGTCACTATTACCAGTAACAGTTGGA
TAATTCAAGAAGGAGAAATTGGTTCAGTGGTTTATGCACTGGAAGATGGT
ATCGTGGAAATAACTATTAAAGGGGAAAAGCTTCGACAAATGACAACGGG
TTCAATTTTCGGAGAACTAGCAATATTATATAATTGCACTAGAACTGCCA
GTGTTAGAGCCAAGACCAAATGCAAGCTCTGGACAATTGACCGAGAAAGC
TTTCAGTCTATAATGATGAAGTCGGGTATTCGAAGGCAAGAAGAATATGT
AAAATTTCTTCAAAGTGTCCCAACATTCAAGGAATTACAAATGGAAAAAC
TAATAAAAATCGCTGATGTTCTGGGTGAAAATCATTACAACAAAGATGAT
TATATTATTCGTGAAGGCGCTCGTGGTGATACATTTTATATCATATCAAA
GGGAAAAGTAAAAGTAACAAAAAAGTGTGGGAAAAATAATGAAAATGAAA
CTTTTATTAGATATTTAGATAGAGGTCAATGGTTTGGAGAAAAAGCCTTA
AAAGATGAAGATGTTAGAACTGCTAATATAATTGCTGTAGATCATGATGG
GGTAGATTGCTTGGTGCTAGATCGAGATTCTTACAATCTTTTAATAAGAG
ATCTAGTCAATTTCAATCGAGACTACGAAGACGAGAAATTAAGTGACAAG
CAAAGATCCATATTTAACTATCTACAGCTTAAAGATTTATGTTTTGTTGC
TACCATTGGTATCGGTGGATTTGGAAGAGTAGAATTAGTTCAGATAGGAA
ACGATAGAAGTCAGTCTTTTGCTTTGAAGAAACTGAAAAAATATCACATA
GTTGAAACTCGTCAACAAGAACATGTTATCAACGAGAAAAGGATTTTAGA
AGAAGTTGATTCTGAATTCATCGTTAAATTGTACAAAACTTTCAAAGACA
GAAAATATTTATACATGATGATGGAAGTTTGCTTAGGAGGAGAGGTATGG
ACAATATTAAGGGATCGGACTGTATTTGATGATGTAACTGCCAGATTTTA
CACTGCTTGTGTCGTTATGGCTTTAGATTATTTGCACAGAAAAGGAATAG
TTTATCGGGACTTAAAGCCTGAAAACCTAATTTTGGACAGTAAAGGCTAT
TGTAAAATTACAGATTTCGGATTTTCAAAAAAAATTGGTTTCTTAAGAAA
AACATGGACATTCTGTGGTACTCCAGAATATGTTGCTCCTGAAATAATTT
TAAATAAAGGACATGACTTTTCAGCAGATTTTTGGTCTCTTGGAATTTTA
ATGTTTGAATTACTTACTGGCACTCCCCCATTCAGCACATCGGACCCAAT
GAAGACTTATAATATAATATTGAAGGGTATTGAAGCTATTGAAGTTCCAG
TAACAATGTCCAAAAATGCATACAATCTTATTAAAAAGTTGAGCAGAGAC
AATCCTTTGGAACGACTCGGTTATGGTAAAAAGGGGATTTTAGAAGTTCA
AAAGCACGTATGGTTTGAAGGATTTAATTGGAATGGGTTAGTATGCAGAG
CCATTCAGCCACCTATAATTCCTAAAGTGAAATCAGCCATTGATCATTCC
AATTTCGACAGTTATCCTCCAGATGAAGATGTGCCCCCTGACGACATATC
AGGATGGGATAATGAATTTGAAATGTTTTCAACTTAAAATTAACTTAAGT
TTTTCTGTTTGTTTGATATATTTAATACCGTTTTGTTCTATGAATATATT
ACGAATTTTCTC
back to top

protein sequence of SMED30025573-orf-1

>SMED30025573-orf-1 ID=SMED30025573-orf-1|Name=SMED30025573-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=690bp
MNSQSVESNNNSTKNNETTCKELDEFKNKLAKKEIEIKRLLETIQIKNEQ
IAELEKDLKYFKNIPVKLQKKEVRGIGISAEPRGLNFNYDSLAKGLNHVA
KEKKTKECLVRAILENDFMRHLSANQISDLVENMYPVTITSNSWIIQEGE
IGSVVYALEDGIVEITIKGEKLRQMTTGSIFGELAILYNCTRTASVRAKT
KCKLWTIDRESFQSIMMKSGIRRQEEYVKFLQSVPTFKELQMEKLIKIAD
VLGENHYNKDDYIIREGARGDTFYIISKGKVKVTKKCGKNNENETFIRYL
DRGQWFGEKALKDEDVRTANIIAVDHDGVDCLVLDRDSYNLLIRDLVNFN
RDYEDEKLSDKQRSIFNYLQLKDLCFVATIGIGGFGRVELVQIGNDRSQS
FALKKLKKYHIVETRQQEHVINEKRILEEVDSEFIVKLYKTFKDRKYLYM
MMEVCLGGEVWTILRDRTVFDDVTARFYTACVVMALDYLHRKGIVYRDLK
PENLILDSKGYCKITDFGFSKKIGFLRKTWTFCGTPEYVAPEIILNKGHD
FSADFWSLGILMFELLTGTPPFSTSDPMKTYNIILKGIEAIEVPVTMSKN
AYNLIKKLSRDNPLERLGYGKKGILEVQKHVWFEGFNWNGLVCRAIQPPI
IPKVKSAIDHSNFDSYPPDEDVPPDDISGWDNEFEMFST*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR002374cGMP_dep_kinase
IPR000595cNMP-bd_dom
IPR000961AGC-kinase_C
IPR000719Prot_kinase_dom
IPR014710RmlC-like_jellyroll
IPR018488cNMP-bd_CS
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR018490cNMP-bd-like
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004692cGMP-dependent protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation