Tetraspanin

Overview
NameTetraspanin
Smed IDSMED30025558
Length (bp)939
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Tetraspanin (SMED30025558) t-SNE clustered cells

Violin plots show distribution of expression levels for Tetraspanin (SMED30025558) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tetraspanin (SMED30025558) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tetraspanin (SMED30025558) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025558

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30025558SMESG000044356.1 dd_Smed_v4_2452_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025558SMESG000044356.1 dd_Smed_v4_2452_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30025558SMESG000044356.1 dd_Smed_v4_2452_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30025558SMESG000044356.1 dd_Smed_v4_2452_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025558SMESG000044356.1 Contig39471uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025558SMESG000044356.1 Contig39471newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30025558SMESG000044356.1 dd_Smed_v4_2452_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN3 (tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752])

HSP 1 Score: 75.485 bits (184), Expect = 3.720e-15
Identity = 60/215 (27.91%), Postives = 109/215 (50.70%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNM--KCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
              + +  ++G+Y+          ++  + LIP +VI++VG +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G V++ K++  +D+ + K+ K Y+     +  + IDY+Q  L CCG+ NY+DW       E  N S+P SCCR     C   L+           + Y  GC   V K +Q   +++I   ++  A+Q++ ++
Sbjct:   22 GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPS--------DLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGML 228
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN6 (tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858])

HSP 1 Score: 75.0998 bits (183), Expect = 4.319e-15
Identity = 51/160 (31.87%), Postives = 73/160 (45.62%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            FGC    +    +L ++   L LVFL EL A  +G VF+++IK +      K LK Y++    R   +D IQ+TL CCGV +Y DW   N       P SCC+   C P           DA +    GC   V  +I+ +   +  I   V   Q+I +
Sbjct:   77 FGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTP---------QRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGI 227
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN6 (tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858])

HSP 1 Score: 72.0182 bits (175), Expect = 6.646e-15
Identity = 38/105 (36.19%), Postives = 54/105 (51.43%), Query Frame = 1 
Query:  274 LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQTT 573
            +L ++   L LVFL EL A  +G VF+++IK +      K LK Y++    R   +D IQ+TL CCGV +Y DW   N       P SCC+   C P   + +  
Sbjct:    1 MLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVN 105
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: TSPAN6 (tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858])

HSP 1 Score: 71.2478 bits (173), Expect = 8.545e-15
Identity = 38/103 (36.89%), Postives = 54/103 (52.43%), Query Frame = 1 
Query:  274 LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQ 567
            +L ++   L LVFL EL A  +G VF+++IK +      K LK Y++    R   +D IQ+TL CCGV +Y DW   N       P SCC+   C P   + +
Sbjct:    1 MLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADK 103
[Close]
BLAST of Tetraspanin vs. Ensembl Human
Match: CD63 (CD63 molecule [Source:HGNC Symbol;Acc:HGNC:1692])

HSP 1 Score: 73.559 bits (179), Expect = 8.827e-15
Identity = 41/161 (25.47%), Postives = 74/161 (45.96%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE----MYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            F GC     E   L++ F   L L+ L E++A   G VF+ K+ +  +    + ++ Y         +D +Q+  +CCG  NYTDWE    M  N +PDSCC N+     ++  +  I  +       GC E +   ++   + +    + +  ++V+ +V
Sbjct:   46 FVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQMENYPKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVPDSCCINVTVGCGINFNEKAIHKE-------GCVEKIGGWLRKNVLVVAAAALGIAFVEVLGIV 199
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-7 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q9XVI4])

HSP 1 Score: 56.9954 bits (136), Expect = 2.482e-9
Identity = 42/158 (26.58%), Postives = 67/158 (42.41%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDA--YEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            F GC   I E   L V F  LL L+   E++A+ +G       +  I  QL   +  Y     +    D      +CCGV N +DW  +  +IPDSCC        +   +     +A  +EP   GC  +VE+ +      +  I   + A+Q++ +
Sbjct:   68 FLGCCGAIRENYCLTVSFAVLLALLITCEIAAVIIGYALHDSFRLGIGNQLQTGMVRYHESRGVESAWDKTHQLFECCGVTNSSDWLTF-TTIPDSCC--------IEEIEGCARENAPLFEP---GCIHSVEQWVLKNGAMVGGICAVLAAIQLVGV 213
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-8 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q19983])

HSP 1 Score: 53.9138 bits (128), Expect = 3.516e-8
Identity = 29/87 (33.33%), Postives = 44/87 (50.57%), Query Frame = 1 
Query:  244 FFGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLK-FYSTEVSLRKEIDYIQSTLQCCGVQNYTDW 492
            +FGCI   K     L  F  +L L F  EL+A       +  IK  ++  +Y  ++  YS+E + +   D +Q   +CCGV+ YTDW
Sbjct:   72 YFGCIGAWKMNQCALAFFCCILILAFFLELAAAVTLFHKQEHIKHYVESSMYDTIRNRYSSETAFKDAFDTVQEKFECCGVKTYTDW 158
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-21 (Tetraspanin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q5WRN1])

HSP 1 Score: 53.9138 bits (128), Expect = 4.062e-8
Identity = 32/106 (30.19%), Postives = 50/106 (47.17%), Query Frame = 1 
Query:  244 FFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEI------DYIQSTLQCCGVQNYTDWE---MYNNSI--PDSCC 528
            + G     K+LL  +   + L+ L    A   G + K + K  + K +   +   +    + +EI      D++Q  LQCCGV NYTDW     + N++  PDSCC
Sbjct:   77 YLGVSWSNKSLLYSYIGFVILLILVHGIARITGSLHKEEAKENLRKSMLHNINTTAVVTKIGREIKLSLTWDHLQRELQCCGVDNYTDWHYSVHWPNNLYTPDSCC 182
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-21 (Tetraspanin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q5WRN1])

HSP 1 Score: 53.9138 bits (128), Expect = 4.062e-8
Identity = 32/106 (30.19%), Postives = 50/106 (47.17%), Query Frame = 1 
Query:  244 FFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEI------DYIQSTLQCCGVQNYTDWE---MYNNSI--PDSCC 528
            + G     K+LL  +   + L+ L    A   G + K + K  + K +   +   +    + +EI      D++Q  LQCCGV NYTDW     + N++  PDSCC
Sbjct:   77 YLGVSWSNKSLLYSYIGFVILLILVHGIARITGSLHKEEAKENLRKSMLHNINTTAVVTKIGREIKLSLTWDHLQRELQCCGVDNYTDWHYSVHWPNNLYTPDSCC 182
[Close]
BLAST of Tetraspanin vs. Ensembl Celegans
Match: tsp-6 (Tetraspanin [Source:UniProtKB/TrEMBL;Acc:G4RWX0])

HSP 1 Score: 51.6026 bits (122), Expect = 1.952e-7
Identity = 42/154 (27.27%), Postives = 78/154 (50.65%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKT---TIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIAL 687
            FFGC     E    + I+F L+ ++F+ E+ A+ +  V K  ++    TI +   +L+  Y+T+  + + +D IQS+LQCCG    +D+  Y  + P SC    +C  +  +   T+  +++E            LI   FV II++ + ++A+
Sbjct:   84 FFGCCGSCCESICAISIYFILVLILFVVEVVAIVLYFVNKTNLQQGFQTIWRD--ELVSKYNTQQQIHQVLDQIQSSLQCCGASGCSDYIPY-GAFPTSC----QCATIQQAGCATVIWNSFES----------SLIYVAFVGIIILFVELLAM 220
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp74F (gene:FBgn0036769 transcript:FBtr0075155)

HSP 1 Score: 72.4034 bits (176), Expect = 1.302e-14
Identity = 43/157 (27.39%), Postives = 73/157 (46.50%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            F GC+    E K LL+ +F ++ LVF+  L    +G VF+ +++ T+ +++   +  Y +   + +  D  Q  LQCCGV  + DW  Y   +P+SCC+ +         + TI P     Y  GC       I+     I    I+V  L +  ++
Sbjct:   74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNRY-GPVPESCCQELFGG---QRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMI 226
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp74F (gene:FBgn0036769 transcript:FBtr0075154)

HSP 1 Score: 72.4034 bits (176), Expect = 1.302e-14
Identity = 43/157 (27.39%), Postives = 73/157 (46.50%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            F GC+    E K LL+ +F ++ LVF+  L    +G VF+ +++ T+ +++   +  Y +   + +  D  Q  LQCCGV  + DW  Y   +P+SCC+ +         + TI P     Y  GC       I+     I    I+V  L +  ++
Sbjct:   74 FLGCVGAGKEVKCLLLTYFIIVALVFVTMLIGGVLGYVFRERVQQTMRQEMRSTMALYGSRREITQAWDLTQERLQCCGVDTWHDWNRY-GPVPESCCQELFGG---QRKECTIFPTITNLYNQGCLYVTTNFIRDHAAVIGGTSIAVAILMIFGMI 226
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp47F (gene:FBgn0033629 transcript:FBtr0088151)

HSP 1 Score: 65.0846 bits (157), Expect = 6.078e-12
Identity = 34/97 (35.05%), Postives = 52/97 (53.61%), Query Frame = 1 
Query:  247 FGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEM--YNNSIPDSCCR 531
            FG I E  TLL+ F  LL ++F+ EL+      VFK  ++  +   L + +K  ++E ++    D IQ  L CCGV +  DW     N ++P SCC+
Sbjct:   72 FGAIKESPTLLITFAVLLAVIFIVELAVGIAASVFKKDLEGMVKNSLQESIKRSNSEDTM--AWDNIQQKLMCCGVDSPADWRTLSANKTLPGSCCQ 166
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp29Fb (gene:FBgn0032075 transcript:FBtr0079756)

HSP 1 Score: 62.3882 bits (150), Expect = 8.474e-11
Identity = 53/215 (24.65%), Postives = 104/215 (48.37%), Query Frame = 1 
Query:   97 TSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNS------------IPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            T+ + I +G+ I  I G  S L+   H   P  +++++G IL+ +  +G +G + E   ++ ++   L LVF+ E+SA     V + +++  + + + + L  Y  +  +   +D++QS L+CCGV    DW+ Y ++            +P+SCC N     +  STQ T      E Y  GC   +  ++    + I     +V  +Q++ ++
Sbjct:   29 TAILLIMVGTTIQTIFGDFS-LFIDGHFSSPPALLIAIGFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAEYEHDPYVESGVDFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVVPNSCCGNQPTS-LNDSTQMT----CMETYDYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVL 237
[Close]
BLAST of Tetraspanin vs. Ensembl Fly
Match: Tsp29Fb (gene:FBgn0032075 transcript:FBtr0273420)

HSP 1 Score: 62.3882 bits (150), Expect = 8.474e-11
Identity = 53/215 (24.65%), Postives = 104/215 (48.37%), Query Frame = 1 
Query:   97 TSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNS------------IPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            T+ + I +G+ I  I G  S L+   H   P  +++++G IL+ +  +G +G + E   ++ ++   L LVF+ E+SA     V + +++  + + + + L  Y  +  +   +D++QS L+CCGV    DW+ Y ++            +P+SCC N     +  STQ T      E Y  GC   +  ++    + I     +V  +Q++ ++
Sbjct:   29 TAILLIMVGTTIQTIFGDFS-LFIDGHFSSPPALLIAIGFILIAVAALGAYGAVKESVMVINLYGVCLFLVFILEVSAAIAAFVMQSQVRGMLIRTMNQALAEYEHDPYVESGVDFMQSMLECCGVNEPEDWKDYLSANVNFTLGVDDVVVPNSCCGNQPTS-LNDSTQMT----CMETYDYGCFRKMNFIVSQSAMLIATGATTVAFVQLLGVL 237
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan36 (tetraspanin 36 [Source:NCBI gene;Acc:437021])

HSP 1 Score: 98.2117 bits (243), Expect = 8.624e-24
Identity = 62/205 (30.24%), Postives = 106/205 (51.71%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEM------YNNSIPDSCCR-NM-KCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILIS 675
            A  A   ++GSY+I       D     H LIP  +I+ V V++ ++    F GC   + E K  L +F  ++ L+F  E++A   G++++ +I+  ++K +  +   Y    S    +DY+QS L+CCGV+N TDW +      +NN++P SCC+ NM +C   LS       PD       GC   +E+++Q    Y +L+++ 
Sbjct:   21 AAGAALAYVGSYVIKSYNNFEDFMSDRHTLIPAAIIIGVAVVMFIIG---FVGCCATLRESKVGLGLFLIIIMLIFAAEVTAFVFGIIYRGRIRGDLEKSMNDVFLKYDGLNSETHAVDYLQSQLECCGVKNQTDWTLTSWFAQHNNTVPQSCCKANMTQCTGQLS------QPDLLNTQ--GCEAKLEQVLQDVLSYAMLVILG 214
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan36 (tetraspanin 36 [Source:NCBI gene;Acc:437021])

HSP 1 Score: 98.2117 bits (243), Expect = 8.624e-24
Identity = 62/205 (30.24%), Postives = 106/205 (51.71%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEM------YNNSIPDSCCR-NM-KCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILIS 675
            A  A   ++GSY+I       D     H LIP  +I+ V V++ ++    F GC   + E K  L +F  ++ L+F  E++A   G++++ +I+  ++K +  +   Y    S    +DY+QS L+CCGV+N TDW +      +NN++P SCC+ NM +C   LS       PD       GC   +E+++Q    Y +L+++ 
Sbjct:   21 AAGAALAYVGSYVIKSYNNFEDFMSDRHTLIPAAIIIGVAVVMFIIG---FVGCCATLRESKVGLGLFLIIIMLIFAAEVTAFVFGIIYRGRIRGDLEKSMNDVFLKYDGLNSETHAVDYLQSQLECCGVKNQTDWTLTSWFAQHNNTVPQSCCKANMTQCTGQLS------QPDLLNTQ--GCEAKLEQVLQDVLSYAMLVILG 214
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan3b (tetraspanin 3b [Source:ZFIN;Acc:ZDB-GENE-070424-42])

HSP 1 Score: 88.5817 bits (218), Expect = 3.680e-20
Identity = 64/217 (29.49%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFY--STEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSS-TQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  +  IP +VI++VG +L ++    F GC   I E +  LV F  +L LVF  E+  + +G +++ K++  ++  + K+   Y  +   +  + IDY+Q  L CCG+ NY+DW       E  NNS+P SC     CKP +S+ T T + P    P   GC   V K ++   +Y+IL  ++  A+Q++ L+
Sbjct:   22 AAAGILCYIGAYVFITYDDYDHFFEDIYTFIPAMVIIAVGTLLFVIG---FIGCCATIRESRCGLVTFSAVLLLVFATEVVVVVLGYIYRAKVEAVVNHSIQKVYNEYKGTNTDAPSRAIDYVQRQLHCCGIHNYSDWMNTHWFIESKNNSVPVSC-----CKPTISNCTGTLMRPGDLYPE--GCEVLVVKKLKDIMLYVILAALTFAAIQMLGLL 228
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan3b (tetraspanin 3b [Source:ZFIN;Acc:ZDB-GENE-070424-42])

HSP 1 Score: 88.5817 bits (218), Expect = 3.680e-20
Identity = 64/217 (29.49%), Postives = 113/217 (52.07%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFY--STEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSS-TQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  +  IP +VI++VG +L ++    F GC   I E +  LV F  +L LVF  E+  + +G +++ K++  ++  + K+   Y  +   +  + IDY+Q  L CCG+ NY+DW       E  NNS+P SC     CKP +S+ T T + P    P   GC   V K ++   +Y+IL  ++  A+Q++ L+
Sbjct:   22 AAAGILCYIGAYVFITYDDYDHFFEDIYTFIPAMVIIAVGTLLFVIG---FIGCCATIRESRCGLVTFSAVLLLVFATEVVVVVLGYIYRAKVEAVVNHSIQKVYNEYKGTNTDAPSRAIDYVQRQLHCCGIHNYSDWMNTHWFIESKNNSVPVSC-----CKPTISNCTGTLMRPGDLYPE--GCEVLVVKKLKDIMLYVILAALTFAAIQMLGLL 228
[Close]
BLAST of Tetraspanin vs. Ensembl Zebrafish
Match: tspan3a (tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-7787])

HSP 1 Score: 77.0258 bits (188), Expect = 5.054e-16
Identity = 61/214 (28.50%), Postives = 113/214 (52.80%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSS-TQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  + LIP +VI++VG +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G +++ K++  ++  + K+   Y+     +  + IDY+Q  L CCG+ N+ DW       E  NNS+P SC     CKP +S+ T + + P    P   GC E V K ++   +Y+I   ++  A+Q++ ++
Sbjct:   22 AAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILMLVFVTEVVVVVLGYIYRAKVEDEVNHSIQKVYNEYNGTNTDAPSRAIDYVQRQLHCCGITNFADWRNTRWFKESKNNSVPLSC-----CKPNVSNCTGSLLHPGDLYPE--GCEELVVKKLKEIMMYVIWAALTFAAIQMLGML 228
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: ephx2 (epoxide hydrolase 2, cytoplasmic [Source:Xenbase;Acc:XB-GENE-947544])

HSP 1 Score: 78.1814 bits (191), Expect = 2.906e-16
Identity = 60/213 (28.17%), Postives = 110/213 (51.64%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  + LIP ++I++ G +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G +++ K++  +D  +  +   Y+  +  S  + IDY+Q  L CCG+ NY DW       E  NNS+P SCCRN     V + T +   P   + Y  GC   V + +Q   +Y+I   ++  A+Q++ ++
Sbjct:   22 AAAGILCYVGAYVFITYDDYDHFFEDVYTLIPGVIIIAAGTLLFIIGLIGCCATIRESRCGLATFVVILLLVFVTEVVVVVLGYIYRAKVEDEVDNTIANVFNQYNGISPDSASRAIDYVQRQLHCCGIDNYLDWENTPWFSEAKNNSVPLSCCRNY----VFNCTGSMNKPG--DLYSEGCKALVVEKLQEIMMYVIWAALAFAAIQLLGML 228
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: lrrk2 (leucine-rich repeat kinase 2 [Source:Xenbase;Acc:XB-GENE-5768572])

HSP 1 Score: 74.7146 bits (182), Expect = 4.336e-15
Identity = 44/148 (29.73%), Postives = 76/148 (51.35%), Query Frame = 1 
Query:  286 FFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE-----MYNNSIPDSCCRN--MKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVA 708
            F  L+ ++F   ++A+ +GLVF  KI   ++K +  L K Y+        +D+IQ  L+CCG +NYTDWE       N S+P SCC+     C+ V+   Q  I  +A EP        +E LI     Y + +++    +++ ++++
Sbjct:   85 FMFLISIIFAAGVAAMILGLVFVDKINPELEKNMDNLFKTYNGVDVSSSTVDFIQERLECCGRKNYTDWEETDWYQTNKSLPMSCCKKNAQDCQRVIGQ-QKDIYTEACEP-------KLENLIHQVLRYSMFVILGFAIVELFAMIS 224
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: lrrk2 (leucine-rich repeat kinase 2 [Source:Xenbase;Acc:XB-GENE-5768572])

HSP 1 Score: 74.3294 bits (181), Expect = 5.913e-15
Identity = 44/148 (29.73%), Postives = 76/148 (51.35%), Query Frame = 1 
Query:  286 FFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE-----MYNNSIPDSCCRN--MKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVA 708
            F  L+ ++F   ++A+ +GLVF  KI   ++K +  L K Y+        +D+IQ  L+CCG +NYTDWE       N S+P SCC+     C+ V+   Q  I  +A EP        +E LI     Y + +++    +++ ++++
Sbjct:   92 FMFLISIIFAAGVAAMILGLVFVDKINPELEKNMDNLFKTYNGVDVSSSTVDFIQERLECCGRKNYTDWEETDWYQTNKSLPMSCCKKNAQDCQRVIGQ-QKDIYTEACEP-------KLENLIHQVLRYSMFVILGFAIVELFAMIS 231
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: sertad4 (SERTA domain containing 4 [Source:Xenbase;Acc:XB-GENE-943347])

HSP 1 Score: 72.0182 bits (175), Expect = 5.031e-14
Identity = 38/103 (36.89%), Postives = 58/103 (56.31%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCR 531
            FGC    +    +L ++   L ++FL EL A  +GLVF+++IK + ++   + LK Y+     R + +D IQ TLQCCGV +Y +W        + IP SCCR
Sbjct:   77 FGCFATCRASTWMLKLYAMFLSIIFLVELIAAIVGLVFRHEIKNSFEQGYLQALKQYNATGDPRSQAVDTIQRTLQCCGVNSYNEWGQTQYYKTHGIPQSCCR 179
[Close]
BLAST of Tetraspanin vs. Ensembl Xenopus
Match: trip4 (thyroid hormone receptor interactor 4 [Source:Xenbase;Acc:XB-GENE-974186])

HSP 1 Score: 71.633 bits (174), Expect = 5.746e-14
Identity = 41/162 (25.31%), Postives = 76/162 (46.91%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMY-----NNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGC   + E   ++  F  +L L+FL E++A     V+K K++T  +      +  Y+    +   ID +Q   QCCG  N TDW  Y      N++PDSCC+N+         +  I+    E    GC+  +++ ++     +  + + +   +++ +V
Sbjct:   64 FFGCCGALKENYCMVTTFAVVLVLIFLVEIAAAIAAYVYKDKLRTAFEDSFKNGMVHYNDTKDIADSIDLLQKEFQCCGAINSTDWRQYAPFTGTNTVPDSCCKNI----TAGCGKGPIANINSE----GCATGIDQWVKKNVGIVAGVALGIALFEILGIV 217
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan6 (tetraspanin 6 [Source:MGI Symbol;Acc:MGI:1926264])

HSP 1 Score: 77.0258 bits (188), Expect = 5.834e-16
Identity = 52/160 (32.50%), Postives = 73/160 (45.62%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            FGC    +    +L ++   L L+FL EL A  +G VF+++IK +        LK Y++    R E +D IQSTL CCGV NY DW+  N       P SCC+   C P           DA +    GC   V   I+ +   +  I   V   Q+I +
Sbjct:   77 FGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCKLEGCYP---------QRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGI 227
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan7 (tetraspanin 7 [Source:MGI Symbol;Acc:MGI:1298407])

HSP 1 Score: 75.8702 bits (185), Expect = 1.627e-15
Identity = 46/161 (28.57%), Postives = 76/161 (47.20%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE----MYNNSIPDSCCRN-MKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FGC    +    +L ++   L LVFL EL A   G VF+++IK T  +     ++ Y+      + +D++Q +L CCGVQNYT+W       ++ IP SCC N   C P+     T  +    +    GC + V   ++     I  +   +   Q+I ++
Sbjct:   75 FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQK---GCYDLVTSFMETNMGIIAGVAFGIAFSQLIGML 232
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan7 (tetraspanin 7 [Source:MGI Symbol;Acc:MGI:1298407])

HSP 1 Score: 75.0998 bits (183), Expect = 1.968e-15
Identity = 39/110 (35.45%), Postives = 59/110 (53.64%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE----MYNNSIPDSCCRN-MKCKPV 552
            FGC    +    +L ++   L LVFL EL A   G VF+++IK T  +     ++ Y+      + +D++Q +L CCGVQNYT+W       ++ IP SCC N   C P+
Sbjct:   75 FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPL 184
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan6 (tetraspanin 6 [Source:MGI Symbol;Acc:MGI:1926264])

HSP 1 Score: 73.559 bits (179), Expect = 2.315e-15
Identity = 38/90 (42.22%), Postives = 49/90 (54.44%), Query Frame = 1 
Query:  295 LLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKP 549
             L L+FL EL A  +G VF+++IK +        LK Y++    R E +D IQSTL CCGV NY DW+  N       P SCC+   C P
Sbjct:   47 FLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCKLEGCYP 136
[Close]
BLAST of Tetraspanin vs. Ensembl Mouse
Match: Tspan3 (tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098])

HSP 1 Score: 75.0998 bits (183), Expect = 3.495e-15
Identity = 60/213 (28.17%), Postives = 110/213 (51.64%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVS--LRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
              + +  ++G+Y+          ++  + L P +VI++VG +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G V++ K++  +D+ + K+ K Y+   S    + IDY+Q  L CCG+ NY+DW       E  N S+P SCCR    +   S   +  +P   + Y  GC   V K +Q   +++I   ++  A+Q++ ++
Sbjct:   22 GAAGILCYVGAYVFITYDDYDHFFEDVYTLFPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCR----ETAKSCNGSLANPS--DLYAEGCEALVVKKLQEILMHVIWAALAFAAIQLLGML 228
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q6NWG0|TSN36_DANRE (Tetraspanin-36 OS=Danio rerio OX=7955 GN=tspan36 PE=1 SV=2)

HSP 1 Score: 98.2117 bits (243), Expect = 6.510e-23
Identity = 62/205 (30.24%), Postives = 106/205 (51.71%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEM------YNNSIPDSCCR-NM-KCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILIS 675
            A  A   ++GSY+I       D     H LIP  +I+ V V++ ++    F GC   + E K  L +F  ++ L+F  E++A   G++++ +I+  ++K +  +   Y    S    +DY+QS L+CCGV+N TDW +      +NN++P SCC+ NM +C   LS       PD       GC   +E+++Q    Y +L+++ 
Sbjct:   21 AAGAALAYVGSYVIKSYNNFEDFMSDRHTLIPAAIIIGVAVVMFIIG---FVGCCATLRESKVGLGLFLIIIMLIFAAEVTAFVFGIIYRGRIRGDLEKSMNDVFLKYDGLNSETHAVDYLQSQLECCGVKNQTDWTLTSWFAQHNNTVPQSCCKANMTQCTGQLS------QPDLLNTQ--GCEAKLEQVLQDVLSYAMLVILG 214
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|O70401|TSN6_MOUSE (Tetraspanin-6 OS=Mus musculus OX=10090 GN=Tspan6 PE=1 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 1.073e-15
Identity = 53/160 (33.12%), Postives = 74/160 (46.25%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            FGC    +T   +L ++   L L+FL EL A  +G VF+++IK +        LK Y++    R E +D IQSTL CCGV NY DW+  N       P SCC+   C P           DA +    GC   V   I+ +   +  I   V   Q+I +
Sbjct:   77 FGCFATCRTSAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKSNYENALKEYNSTGDYRSEAVDKIQSTLHCCGVTNYGDWKGTNYYSETGFPKSCCKLEGCYP---------QRDADKVNEEGCFIKVMTTIESEMGVVAGISFGVACFQLIGI 227
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q32KU6|TSN6_BOVIN (Tetraspanin-6 OS=Bos taurus OX=9913 GN=TSPAN6 PE=2 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.503e-15
Identity = 51/160 (31.87%), Postives = 75/160 (46.88%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMYN----NSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            FGC    +    +L ++   L L+FL EL A  +G VF+++IK ++     K LK Y+     R + +D IQS L CCGV NY DW+  N       P+SCC+   C P           DA +    GC   V  +I+ +   +  I   V   Q+I +
Sbjct:   77 FGCFATCRASAWMLKLYAMFLTLIFLVELVAAIIGFVFRHEIKNSLKNNYEKALKQYNATGDYRSDAVDKIQSMLHCCGVTNYRDWKDTNYYSEKGFPESCCKLEDCSP---------QRDADKVNNEGCFIMVMTIIESEMGVVAGISFGVACFQLIGI 227
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q3SZR9|TSN3_BOVIN (Tetraspanin-3 OS=Bos taurus OX=9913 GN=TSPAN3 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 5.827e-15
Identity = 60/213 (28.17%), Postives = 111/213 (52.11%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
              + +  ++G+Y+          ++  + LIP +VI++VG +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G V++ K++  +D+ + K+ K Y+     +  + IDY+Q  L CCG+ NY+DW       E  N S+P SCCR    +   S   +  +P   + Y  GC   V K +Q   +++I   ++  A+Q++ ++
Sbjct:   22 GAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCR----ETASSCNGSLANPS--DLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGML 228
[Close]
BLAST of Tetraspanin vs. UniProt/SwissProt
Match: sp|Q62283|TSN7_MOUSE (Tetraspanin-7 OS=Mus musculus OX=10090 GN=Tspan7 PE=1 SV=2)

HSP 1 Score: 75.8702 bits (185), Expect = 1.138e-14
Identity = 46/161 (28.57%), Postives = 76/161 (47.20%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE----MYNNSIPDSCCRN-MKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FGC    +    +L ++   L LVFL EL A   G VF+++IK T  +     ++ Y+      + +D++Q +L CCGVQNYT+W       ++ IP SCC N   C P+     T  +    +    GC + V   ++     I  +   +   Q+I ++
Sbjct:   75 FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSSSPYFLDHGIPPSCCMNETDCNPLDLHNLTVAATKVNQK---GCYDLVTSFMETNMGIIAGVAFGIAFSQLIGML 232
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A267GIP3 (Tetraspanin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028043g1 PE=3 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 4.074e-29
Identity = 82/212 (38.68%), Postives = 126/212 (59.43%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDW------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIA-LQVISLVA 708
            A SA  I +G+ + H +G+I  + KST+ L+PT++IL  G+ L LL +IG F CI E + LL  FF LL L+ L E++A TMG+V+  ++++ ID +L K L+ Y  +  L+ E+D+IQST QCCGV N+TDW        +N ++PDSCCR+ +C    + T  T+    +     GC   +      +F+ +I     V+A LQ + L+A
Sbjct:   23 AASACLIVVGAVVWHGAGSIDSIAKSTYALVPTVIILGSGIFLFLLGVIGCFACINENRCLLSTFFILLLLILLGEITAATMGIVYHGQVRSAIDTELNKELQSYHNDSLLKSEVDFIQSTYQCCGVNNFTDWLETPWSRQHNLTVPDSCCRDHRC----NDTDPTVDSQVFHS---GCLSKLNYDFS-RFLGLIAAFSLVVAILQALGLLA 226
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A3Q3FLQ9 (Tetraspanin OS=Labrus bergylta OX=56723 PE=3 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 2.400e-22
Identity = 69/229 (30.13%), Postives = 120/229 (52.40%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEM------YNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYII-GCSETVEKLIQHKFVYIILILISVIALQVISLVAXXXXXXXXXXXXXDYQP 759
            A  A+  ++G+Y+I      ++  +  + LIP  +I+ V V++ +  L+G F  I E +  L  FF  + ++F  E++AL    +++YKI   + + +  +   Y  E +  K +DY+Q+ LQCCGV+NYT W        +NN++P SCC+N      ++STQ T   D  +     GC   +E L+Q    Y +L+++    ++   +++ C I    SS  S YQP
Sbjct:   21 AAGALMAYVGAYVIKSYDNFNNFIQDKYTLIPAAIIIGVSVVMFIFGLLGCFATIRESRVGLSFFFLFIMVIFAAEIAALVFSFIYQYKISGDLQRSMSDVFDRYDGEDAETKAVDYLQTQLQCCGVRNYTSWSSTTWYANHNNTVPLSCCKN------VTSTQCTGRQDQVDLLNTEGCESKLEVLLQDVLGYAMLVILGFAIIKFFGMLSVCVITCRASSRRSGYQP 243
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1S3JM91 (Tetraspanin OS=Lingula unguis OX=7574 GN=LOC106174466 PE=3 SV=1)

HSP 1 Score: 100.908 bits (250), Expect = 2.882e-21
Identity = 65/214 (30.37%), Postives = 110/214 (51.40%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIM---EKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMY-----NNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYII--GCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A +A   +LGSYI        DL    + L+P ++ L+ GV + L+      GCI    E K LL  FF+L+ ++ + E+ + T+  V++  +   +      ++K Y+ + + R E+DY+Q  L CCG  NYTDWE +     N+S+P+SCC++       ++  T IS     PYI   GC + +E L++     + ++ I    + VI L+
Sbjct:   21 AAAAGLFYLGSYIFVTYKHYDDLADQKYTLVPAVITLAAGVFMFLVG---LLGCIAACKEHKCLLATFFSLILVILVAEVVSGTLAYVYRADVSDALKDGFDAVMKNYTNDATYRDEMDYVQDQLMCCGRHNYTDWERFEFYRQNHSVPESCCKDK------NNCTTKISGYVDNPYIYEEGCYDKLEDLLRDSLAVLAVVAIIFAVILVIGLI 225
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A1I8FUB0 (Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 103.605 bits (257), Expect = 9.835e-21
Identity = 62/133 (46.62%), Postives = 91/133 (68.42%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDW 492
            A SA  I +G+ + H +G+I  + KST+ L+PT++IL  G+ L LL +IG F CI E + LL  FF LL L+ L E++A TMG+V+  ++++ ID +L K L+ Y  +  L+ E+D+IQST QCCGV N+TDW
Sbjct:  654 AASACLIVVGAVVWHGAGSIDSIAKSTYALVPTVIILGSGIFLFLLGVIGCFACINENRCLLSTFFILLLLILLGEITAATMGIVYHGQVRSAIDTELNKELQSYHNDSLLKSEVDFIQSTYQCCGVNNFTDW 786
[Close]
BLAST of Tetraspanin vs. TrEMBL
Match: A0A195ELC8 (Tetraspanin OS=Trachymyrmex cornetzi OX=471704 GN=ALC57_01937 PE=3 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 3.499e-20
Identity = 51/160 (31.87%), Postives = 81/160 (50.62%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEP---YIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGCI    E K +L+ +F ++ L+F+  L    +G +F+ K+ +T+D+++   L+ Y    S+R   D  QSTL CCGV N+ DW  Y  ++PDSCCR +      +      SPD+  P   Y+ GC       +Q     +    I+V  L    ++
Sbjct:   75 FFGCIGASREVKCMLLTYFIIVFLLFVTMLIGGVLGYIFREKLLSTVDREMKSSLRLYDHRKSIRDAWDTTQSTLHCCGVNNWRDWGTYGLNVPDSCCREISPGQRFNCNH---SPDSINPSNAYVEGCINGTRVYMQQHATVVGAAGIAVACLMFFGMI 231
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan36 (tetraspanin 36 [Source:NCBI gene;Acc:437021])

HSP 1 Score: 97.0561 bits (240), Expect = 1.676e-23
Identity = 66/205 (32.20%), Postives = 106/205 (51.71%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE------MYNNSIPDSCCR-NMKC-----KPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILI 672
            A  A   ++G+Y+I    T  +  +  + LIP  +I+ V V+L ++ LIG    + E K  L  F  +L LVF  E++A   G +++ KIK  ++K +  + + Y  + +    +DY+QS LQCCGV NYTDW        +N+++P SCC+ N  C     KP L + Q             GC   +EKL+Q    Y +L+++
Sbjct:   21 AAGAALSYVGAYVIKSYRTFDNFLEDKYTLIPAAIIIGVAVVLFIIGLIGCCATLRESKVGLSFFMVILLLVFAAEVAAFVFGFIYRGKIKGDLEKSMSDVFQKYDGKNAETAAVDYLQSQLQCCGVNNYTDWSSRPWFTSHNSTVPVSCCKANSTCTGQFDKPELLNVQ-------------GCEAKLEKLLQDVLSYAMLVIL 212
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan36 (tetraspanin 36 [Source:NCBI gene;Acc:437021])

HSP 1 Score: 95.1301 bits (235), Expect = 9.984e-23
Identity = 66/202 (32.67%), Postives = 103/202 (50.99%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE------MYNNSIPDSCCR-NMKC-----KPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIIL 663
            A  A   ++G+Y+I    T  +  +  + LIP  +I+ V V+L ++ LIG    + E K  L  F  +L LVF  E++A   G +++ KIK  ++K +  + + Y  + +    +DY+QS LQCCGV NYTDW        +N+++P SCC+ N  C     KP L + Q             GC   +EKL+Q    Y +L
Sbjct:   21 AAGAALSYVGAYVIKSYRTFDNFLEDKYTLIPAAIIIGVAVVLFIIGLIGCCATLRESKVGLSFFMVILLLVFAAEVAAFVFGFIYRGKIKGDLEKSMSDVFQKYDGKNAETAAVDYLQSQLQCCGVNNYTDWSSRPWFTSHNSTVPVSCCKANSTCTGQFDKPELLNVQ-------------GCEAKLEKLLQDVLSYAML 209
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:103032697])

HSP 1 Score: 81.6481 bits (200), Expect = 8.946e-18
Identity = 46/161 (28.57%), Postives = 80/161 (49.69%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMY---NNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGC     E   ++ +F  LL L+ + E+       VF+ K+   +D  L  ++K Y+      +E +D IQ  L+CCG  N +DW  +   + S+PDSCC+N     V +        D  + Y+ GC   +EKL++    ++ +  I +  ++++ LV
Sbjct:   69 FFGCCGAWKENYCMVTMFAILLSLIIIVEIGTAIAAYVFRDKLTGLVDDGLRDMIKQYNNGSKEYQEGLDRIQKDLKCCGAANSSDWVNFKPDHTSVPDSCCKN-----VTADCGKGAMNDDKKIYVTGCQPALEKLLKENVQWVAVAAIVIAFIEILGLV 224
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:103032697])

HSP 1 Score: 80.8777 bits (198), Expect = 2.564e-17
Identity = 46/161 (28.57%), Postives = 80/161 (49.69%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEMY---NNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGC     E   ++ +F  LL L+ + E+       VF+ K+   +D  L  ++K Y+      +E +D IQ  L+CCG  N +DW  +   + S+PDSCC+N     V +        D  + Y+ GC   +EKL++    ++ +  I +  ++++ LV
Sbjct:   90 FFGCCGAWKENYCMVTMFAILLSLIIIVEIGTAIAAYVFRDKLTGLVDDGLRDMIKQYNNGSKEYQEGLDRIQKDLKCCGAANSSDWVNFKPDHTSVPDSCCKN-----VTADCGKGAMNDDKKIYVTGCQPALEKLLKENVQWVAVAAIVIAFIEILGLV 245
[Close]
BLAST of Tetraspanin vs. Ensembl Cavefish
Match: tspan3a (tetraspanin 3 [Source:NCBI gene;Acc:103046031])

HSP 1 Score: 77.0258 bits (188), Expect = 4.454e-16
Identity = 61/213 (28.64%), Postives = 112/213 (52.58%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVS--LRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  + LIP +VI++VG +L ++ LIG    I E +  L  F  +L LVF+ E+  + +G +++ K++  ++  + K+   Y+   S    + IDY+Q  L CCG+ NY DW       E  NNS+P SC     CKP +S+   ++S    + Y  GC   V K ++   +Y+I   ++  A+Q++ ++
Sbjct:   24 AAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGGLLFIIGLIGCCATIRESRCGLATFVIILILVFVTEVVVVVLGYIYRAKVEEEVNHSIQKVYNEYNGTNSDAPSRAIDYVQRQLHCCGITNYLDWRNTSWFNESRNNSVPLSC-----CKPNVSNCTGSLSRPG-DLYPEGCEALVVKKLKEIMMYVIWAALTFAAIQMLGML 230
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan3a (tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-7787])

HSP 1 Score: 77.411 bits (189), Expect = 8.662e-17
Identity = 47/156 (30.13%), Postives = 76/156 (48.72%), Query Frame = 1 
Query:  250 GC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVS--LRKEIDYIQSTLQCCGVQNYTDWE-------MYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEP---YIIGCSETVEKLIQHKFVYIILILI 672
            GC   + E K  L  FF LL ++F  E+ A  +G  ++ ++K  +++ + ++   Y+   S    + IDY+Q  L+CCGV+NY DW+         NNS+P SCCR         S  T    +   P   Y  GC   VEK ++    Y++ + +
Sbjct:   73 GCCATVRESKCGLSTFFILLLMIFSLEVVAALLGYAYRGQVKDKVERTISQVFNEYNGTDSNTASRAIDYVQHQLKCCGVKNYLDWKDRPWFNHTGNNSVPISCCR---------SNVTHCDGNIKHPGDIYNEGCEAMVEKTVKDILNYVMRVAL 219
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009492.1 (pep scaffold:Pmarinus_7.0:GL476618:258874:270129:-1 gene:ENSPMAG00000008573.1 transcript:ENSPMAT00000009492.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 75.0998 bits (183), Expect = 4.500e-16
Identity = 58/216 (26.85%), Postives = 105/216 (48.61%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEV--SLRKEIDYIQSTLQCCGVQNYTDWEMYN-------NSIPDSCCRN--MKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVA 708
            A +AVF + G+Y+          ++  + ++P + I+  G +L+L+ +IG +  + E +  L  F  LL ++F  E++A+ +G ++  K++  + ++++K  + Y         + +DY+Q  LQCCG  NY+DW           NS+P SCC+     C  +LS             Y  GC   +   +Q    Y+I + +    LQV+ LVA
Sbjct:   22 AAAAVFCYAGAYVFITYDRYDHFFEDRYTILPALAIIVAGAVLLLIGVIGCWAAVRESRCALASFALLLLIIFSLEVAAVALGYIYHGKVEVEVQQKMHKAFQNYMGPDYDPESRAVDYMQKELQCCGFANYSDWNTTEWARRHKYNSVPLSCCKRSAKNCTGLLSLPAKL--------YQQGCLLKLGDEVQQILTYLIGVAVGFAFLQVMGLVA 229
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan17 (tetraspanin 17 [Source:ZFIN;Acc:ZDB-GENE-030131-3673])

HSP 1 Score: 72.0182 bits (175), Expect = 8.017e-15
Identity = 49/176 (27.84%), Postives = 80/176 (45.45%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWE--MYNN-----------SIPDSCCRNMKCKPVLSST-------QTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            F GCI    E   LL  F T L L+F  EL+A  +  VFK  ++  ++  +Y  +K Y  ++ L+  ID+ Q   QCCG     DW+  +Y N            +P SCC     + V+++        +T +   +Y  Y  GC    EK +Q+  + +  I I +  +Q+  +
Sbjct:   62 FAGCIGALRENTYLLKFFSTFLGLIFFLELTAGVLAFVFKDWLRDQLNFFIYNNVKAYRDDIDLQNLIDFAQDYWQCCGAHGPLDWDENIYFNCSIKNRSREKCGVPFSCCVKDPAEDVVNTQCGYDVRLKTELDQQSY-IYTKGCVTQFEKWLQNNLILVAGIFIGIALVQIFGI 236
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: tspan4a (tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38])

HSP 1 Score: 70.0922 bits (170), Expect = 2.339e-14
Identity = 41/156 (26.28%), Postives = 75/156 (48.08%), Query Frame = 1 
Query:  250 GCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTE--VSLRKEIDYIQSTLQCCGVQNYTDW--EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            G I E K LL+ FF  L ++F+ E+  + +  +++ +I       L + L+ Y +E  V L    + +Q+   CCGV N+TDW     +  +PDSCC         S       P+ + P   GC + VE  I+   + + + ++ +  +Q++ + 
Sbjct:   69 GAIKEHKCLLLSFFVCLLIIFVLEMICVILFFMYRDQIDGHAKDDLKEGLRLYGSEGNVGLTNAWNIVQTDFHCCGVVNHTDWFLAFGDKRVPDSCCME------YSVDCGRDKPNTWWPS--GCYDKVEAWIEENLMVLGVFILCISLIQILGMA 216
[Close]
BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005284.1 (pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 gene:ENSPMAG00000004798.1 transcript:ENSPMAT00000005284.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 63.5438 bits (153), Expect = 4.805e-12
Identity = 44/168 (26.19%), Postives = 75/168 (44.64%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYN------------NSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FGC    K    ++  F   L L+F+ EL+A     +FK +++  ++ +   ++  Y T+   +  +D +Q  LQCCGV +Y DW  +N            NS+PDSCC N+                    Y  GC E +E  ++   V +  + I +   Q+I ++
Sbjct:   77 FGCCGAHKESYFMVATFSVFLFLIFVAELAAGIGAYIFKDQLRDVVETKAKVVINDYPTKN--KDPVDNMQKELQCCGVVHYQDW--FNSTNWVTSDPNNPNSVPDSCCLNVTSG--CGQDDIRFKNATAIIYTKGCVEKLEATMKENIVLVGGVAIGIGFAQLIGII 238
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO30837 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZN5])

HSP 1 Score: 79.337 bits (194), Expect = 2.927e-17
Identity = 55/169 (32.54%), Postives = 78/169 (46.15%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMY--------NNSIPDSCCRNMKCK----PVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            F GC   + E   LL  F  +L L+FL EL     G +F+ +IKT +   L   LK Y  E   +   + +Q  L+CCG +NYTDW M         N S+P+SCC++ K K     VLS  +T  S         GC     K  + K V I  + + +   Q+I + 
Sbjct:   72 FIGCCGALKEHTCLLKTFGVILGLLFLVELGTAITGYIFRSEIKTGLSDGLDTALKDYP-EQGFKDAWNDMQKNLKCCGSRNYTDWFMVAWAGPNTKNGSVPESCCKDTKVKSCNLEVLSHPETINSEQ-------GCYGAAVKYFEDKLVIIGGVALGLAVFQLIGIA 232
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO39846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S900])

HSP 1 Score: 71.633 bits (174), Expect = 3.190e-15
Identity = 35/103 (33.98%), Postives = 58/103 (56.31%), Query Frame = 1 
Query:  244 FFGCI---MEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNN-----SIPDSCC 528
            F GC     E K +L+ FF  + ++F  E++A  +  V K K+K  ++ +L   +K Y+   S R  +D +Q T++CCG+  Y DW+  +N     ++PDSCC
Sbjct:   64 FLGCCGAWKESKCMLICFFVCMLILFCLEIAAAVLAFVKKDKVKDELENELKNQIKSYTG--SARNAVDDMQKTVKCCGITTYEDWKSSDNLGLTDNVPDSCC 164
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO47592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLE8])

HSP 1 Score: 71.2478 bits (173), Expect = 1.536e-14
Identity = 47/165 (28.48%), Postives = 82/165 (49.70%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEV--SLRKEIDYIQSTLQCCGVQNYTDWEMY-----NNSI-PDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGC   I E + LL  FF LL ++   E++   +G V++ K++  + K +   +  Y  +    +    D IQ   +CCG+  + DW+       N+SI PDSCC+ +       S    I+    + Y  GC +TV+ L++   + I  I I V  +Q+++++
Sbjct:   69 FFGCCGAIKEHRCLLATFFALLFIILAVEITGTALGYVYRNKVEEQLGKDMNDTIVSYGEKGKEGITDAYDAIQKKEKCCGINGFKDWQRSYYTKGNHSIVPDSCCKTV-------SKGCGINFKENDIYTKGCFDTVKTLLKDNLIIIGGIGIGVAVIQILAMI 226
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO34309 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPQ7])

HSP 1 Score: 70.8626 bits (172), Expect = 2.433e-14
Identity = 60/214 (28.04%), Postives = 95/214 (44.39%), Query Frame = 1 
Query:  100 SAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTE-VSLRKEIDYIQSTLQCCGVQNYTDW-----EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPY-----IIGCSETVEKLIQHKFVYIILILISVIALQVISLVA 708
            SA  I++  +++   G  S +   T+ ++P  +I+ VG ++++  L+G  G   E K  L IFF LL +VF  E++A  +G ++K + K  +   L   +  YS E    +K +D +Q  L CCG     DW         + +P SCC              T   D   PY       GC  T+         YII I I    LQ+I +++
Sbjct:   19 SAALIYVAVWLMQSYGNYSKITSDTYTIVPAGIIVGVGCLVLVTALVGICGTCRESKCCLSIFFILLLVVFSLEITAGVLGAIYKNQAKDEVKNGLTDAIDHYSKEEQGFQKAVDKLQENLDCCGSTGPNDWVNSTFWKEKHHLPKSCC--------------THDSDVCFPYDKFHNTKGCYTTLLDKFNKNLSYIIGIGIGFAVLQLIGMLS 218
[Close]
BLAST of Tetraspanin vs. Ensembl Nematostella
Match: EDO47593 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLE9])

HSP 1 Score: 66.2402 bits (160), Expect = 9.086e-13
Identity = 44/164 (26.83%), Postives = 76/164 (46.34%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEV--SLRKEIDYIQSTLQCCGVQNYTDWEM---YNNS---IPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISL 702
            FFGC   I E + LL  FFTLL ++   E +   +G V++ K+   + + +   L  Y  +    +    D IQ   +CCG+  Y DW+     N S   +PDSCC+        +  Q  I+         GC  T+ KL++   + +  + + V  +Q++++
Sbjct:   69 FFGCCGAIKESRCLLAAFFTLLFIILATEAAGTALGFVYRDKVNQKLRQDMNNTLDSYGQKGKEGITLAYDLIQKMEKCCGINGYEDWQQTPFANGSSTLVPDSCCKKETKDCGSNFAQDDINTK-------GCLGTIMKLLKDNLMIVGGVGVGVAVIQILAM 225
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan3a (tetraspanin-3 [Source:NCBI gene;Acc:101170088])

HSP 1 Score: 85.5001 bits (210), Expect = 4.155e-19
Identity = 61/213 (28.64%), Postives = 111/213 (52.11%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  + G+Y+          ++  + LIP +VI++VG +L ++ L+G +  + E    L  F  +L LVFL E++ + +G V++ KI+  ++  +  + + Y+     S  + IDY Q  LQCCG+ NYTDW       +  NNS+P SCC+      V   T +   P+  + +  GC   V K ++   +Y+I   ++  ALQ++ ++
Sbjct:   22 AAAGILCYAGAYVFITYDDYDHFFEDAYTLIPAVVIITVGALLFVIGLVGCYATVRESSCGLTTFVIILLLVFLSEVAVVVLGYVYRAKIEDEVNSSIVVVYEEYNGTNSNSQSRAIDYTQRQLQCCGIHNYTDWLKTRWYEKTKNNSVPISCCKT----TVSGCTGSLTHPE--DLFKEGCEALVVKKLKEIMMYVIWTALTFAALQMMGML 228
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan36 (tetraspanin-36 [Source:NCBI gene;Acc:101167371])

HSP 1 Score: 84.7297 bits (208), Expect = 7.591e-19
Identity = 63/232 (27.16%), Postives = 115/232 (49.57%), Query Frame = 1 
Query:   97 TSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLL-KFYSTEVSLRKEIDYIQSTLQCCGVQNYTDW------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYII---GCSETVEKLIQHKFVYIILILISVIALQVISLVAXXXXXXXXXXXXXDYQPF 762
               V  ++G+ +I    T   L +   +LIP + I+ + V++++  L+G    + E K  L +FF ++ ++F  E++AL +  ++  KI   ++  +     K+   E +  K +D +Q  LQCCGV NYT W        +NNS+P SCCR+       + +Q T   D  +P +I   GC   +E+ +Q    Y +L+++    ++   +++ C I     S  + YQP 
Sbjct:   22 AGGVLAWVGARVIQSYDTFEGLIQDKQILIPAVAIICISVVMLIFGLVGCCSTLRESKFGLTLFFIIIMVIFAAEVAALVLTFIYHGKINQNLEHSMNDTFSKYTGEEDAATKAVDLLQKQLQCCGVLNYTSWTSTTWFASHNNSVPISCCRS-------NVSQCTGRLD--QPNLIYTEGCEVKLERFLQDALTYAMLVVLGFAIIKFFGMLSVCVITCKSKSRRNGYQPL 244
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan3b (tetraspanin-3 [Source:NCBI gene;Acc:101165292])

HSP 1 Score: 75.8702 bits (185), Expect = 1.307e-15
Identity = 59/213 (27.70%), Postives = 111/213 (52.11%), Query Frame = 1 
Query:   94 ATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYS--TEVSLRKEIDYIQSTLQCCGVQNYTDW-------EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            A + +  ++G+Y+          ++  + LIP +VI++VG +L ++ LIG    I E    L  F  +L LVF+ E   + +G +++ K++  ++  + K+   YS     +  + IDY+Q  L CCG+ NY+DW       E  NNS+P SC     C+P +S+   T++    + Y  GC   V K ++   +Y+I   ++  ++Q++ ++
Sbjct:   22 AAAGILCYIGAYVFISYDDYDHFFEDVYTLIPAVVIIAVGTLLFIIGLIGCCATIRESSCGLATFAAILLLVFVTECVVVVLGYIYRAKVEDQVNHSIQKVYNEYSGINSDAPSRAIDYVQKQLHCCGIHNYSDWRNTHWFIESKNNSVPVSC-----CQPNISNCTGTLTRPG-DLYQEGCEALVVKKLKEIMMYVIWAALTFASIQMLGML 228
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: cd63 (CD63 molecule [Source:NCBI gene;Acc:101174188])

HSP 1 Score: 75.0998 bits (183), Expect = 1.746e-15
Identity = 49/161 (30.43%), Postives = 83/161 (51.55%), Query Frame = 1 
Query:  244 FFGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVS-LRKEIDYIQSTLQCCGVQNYTDW---EMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FFGC    K    ++  F  LL L+ + E++A   G VF+ KI   +++ L K+++ Y       +  +D IQ  L+CCGV + +DW   +   NS+PDSCC N K K     +      +A   Y  GC + +E L++    ++I+  I +  +Q++ +V
Sbjct:   69 FFGCCGAWKEHYCMVTTFAVLLTLIIIIEIAAAIAGFVFRNKISPIVNEGLTKMIENYKNGTDDFKATVDQIQENLKCCGVNSSSDWSYLDSDGNSVPDSCCIN-KTKGCGKGSM----KNAGTVYQKGCHDVIENLLKTNIQWVIVAAIVIALVQILGVV 224
[Close]
BLAST of Tetraspanin vs. Ensembl Medaka
Match: tspan7b (tetraspanin 7 [Source:NCBI gene;Acc:101163366])

HSP 1 Score: 73.559 bits (179), Expect = 6.914e-15
Identity = 48/160 (30.00%), Postives = 76/160 (47.50%), Query Frame = 1 
Query:  247 FGCIMEKKT---LLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDW--EMY--NNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            FGC    +    +L ++   L LVFL EL A   G VF+++IK T  +     +  Y+T+    + +DY+Q+ L+CCGV NYT W   +Y     IP SCC N            T++P   + Y  GC + V   ++     I  +   +   Q+I ++
Sbjct:   70 FGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKGTFRRTYTDAVLNYNTQDEASRAVDYLQNKLRCCGVYNYTSWFASVYYPAKGIPPSCCFNSSDCSSDDLRNATVAPS--KVYHQGCFDLVTSFMETNMAIIAGVTFGIAFSQLIGML 227
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000044356.1 (SMESG000044356.1)

HSP 1 Score: 404.445 bits (1038), Expect = 2.200e-143
Identity = 248/248 (100.00%), Postives = 248/248 (100.00%), Query Frame = 1 
Query:   37 MGSKTATKXXXXXXXXXXXATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTXXXXXXXXXXXXXXXXXFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVAXXXXXXXXXXXXXDYQPFNNRYNI 780
            MGSKTATKLILLLGLLVILATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTIVILSVGVILVLLVLIGFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVASCCIIRHRSSSSSDYQPFNNRYNI
Sbjct:    1 MGSKTATKLILLLGLLVILATSAVFIFLGSYIIHISGTISDLYKSTHVLIPTIVILSVGVILVLLVLIGFFGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLVASCCIIRHRSSSSSDYQPFNNRYNI 248
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000063435.1 (SMESG000063435.1)

HSP 1 Score: 64.6994 bits (156), Expect = 5.048e-12
Identity = 36/103 (34.95%), Postives = 56/103 (54.37%), Query Frame = 1 
Query:  244 FFGC---IMEKKTLLVIFFTLLCLVFLFELSALTMGL-VFKYKIKTTIDKQLYKLLKFYST--EVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRN 534
            F GC   I E K +L+IF   L +V L    AL++ + V++  + T I KQ+   +  Y T  + + R  +D  Q   QCCGV + +DW     ++P+SCC+N
Sbjct:   67 FLGCCGAIQESKVMLIIFGVCL-IVLLIAQIALSIAVYVYRSNVSTIIGKQMNDAVNIYKTTNDTAARALVDSTQQLFQCCGVNSTSDW---GKTVPNSCCQN 165
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000043835.1 (SMESG000043835.1)

HSP 1 Score: 62.3882 bits (150), Expect = 5.910e-11
Identity = 46/171 (26.90%), Postives = 80/171 (46.78%), Query Frame = 1 
Query:  247 FGCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQST-LQCCGVQNYTDWE--MYNN---------SIPDSCC--------RNMKC-KPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVI 696
            FG + E  T+L++F   + ++F  E     +  V+K  +   I   L  +L  Y   V LR  ID++Q   L CCG+    DW+  +Y N         ++P SCC        RN+ C + +  S+ + I  +  + Y  GC    +K I++  + +  +L+ +  LQ+I
Sbjct:  109 FGALRENTTMLMLFCITIGIIFCMEAIVCVLTFVYKDWVIDQIKLNLNTILINYRENVDLRDLIDWVQEIWLLCCGIDGPNDWDKNIYFNCSSPSAEKCAVPPSCCKSTPKNNIRNLLCGRMIRDSSMSKIINE--KIYTTGCVYAGQKWIENNIISVAGVLVGIAILQII 277
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000021802.1 (SMESG000021802.1)

HSP 1 Score: 57.7658 bits (138), Expect = 1.533e-9
Identity = 31/101 (30.69%), Postives = 54/101 (53.47%), Query Frame = 1 
Query:  250 GCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKE-IDYIQSTLQCCGVQNYTDWEM-----YNNSIPDSCCRN 534
            G +++    ++    L+ L+  FELSA   G + + ++++   + L   L  Y+ E ++    IDY+Q  ++CCGV N TDW+      Y    PDSCC++
Sbjct:   79 GSLVDGSCQIIGLSALMLLICTFELSAFLSGTLLRSQVESRTRQDLLNQLNKYTMETNITTGYIDYLQQEIKCCGVDNITDWKRKFPSGYIEYYPDSCCKS 179
[Close]
BLAST of Tetraspanin vs. Planmine SMEST
Match: SMESG000043678.1 (SMESG000043678.1)

HSP 1 Score: 57.3806 bits (137), Expect = 1.878e-9
Identity = 37/153 (24.18%), Postives = 71/153 (46.41%), Query Frame = 1 
Query:  250 GCIMEKKTLLVIFFTLLCLVFLFELSALTMGLVFKYKIKTTIDKQLYKLL-KFYSTEVSLRKEIDYIQSTLQCCGVQNYTDWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLIQHKFVYIILILISVIALQVISLV 705
            G   E   LL  +F  L L+F  E++A  + +++K K+K+ +  +  K   +  S        ++ +Q  ++CCG +  +D+      +P SCC   KC+               +PY  GC     +LIQ+ +V    IL+ +  ++++ L+
Sbjct:   74 GAYHESPCLLGTYFIFLLLIFAAEIAAGVLVVLYKDKVKSYVGVKFQKGTEELKSKPDDTEHWMNGVQRNMKCCGYKGSSDY----TKVPGSCCSTSKCE---------------DPYTRGCESAWTELIQNNWVIFASILLGIPLIELLGLI 207
The following BLAST results are available for this feature:
BLAST of Tetraspanin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TSPAN33.720e-1527.91tetraspanin 3 [Source:HGNC Symbol;Acc:HGNC:17752][more]
TSPAN64.319e-1531.88tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858][more]
TSPAN66.646e-1536.19tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858][more]
TSPAN68.545e-1536.89tetraspanin 6 [Source:HGNC Symbol;Acc:HGNC:11858][more]
CD638.827e-1525.47CD63 molecule [Source:HGNC Symbol;Acc:HGNC:1692][more]
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BLAST of Tetraspanin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tsp-72.482e-926.58Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q9XVI4][more]
tsp-83.516e-833.33Tetraspanin [Source:UniProtKB/TrEMBL;Acc:Q19983][more]
tsp-214.062e-830.19Tetraspanin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q... [more]
tsp-214.062e-830.19Tetraspanin-21 [Source:UniProtKB/Swiss-Prot;Acc:Q... [more]
tsp-61.952e-727.27Tetraspanin [Source:UniProtKB/TrEMBL;Acc:G4RWX0][more]
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BLAST of Tetraspanin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tsp74F1.302e-1427.39gene:FBgn0036769 transcript:FBtr0075155[more]
Tsp74F1.302e-1427.39gene:FBgn0036769 transcript:FBtr0075154[more]
Tsp47F6.078e-1235.05gene:FBgn0033629 transcript:FBtr0088151[more]
Tsp29Fb8.474e-1124.65gene:FBgn0032075 transcript:FBtr0079756[more]
Tsp29Fb8.474e-1124.65gene:FBgn0032075 transcript:FBtr0273420[more]
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BLAST of Tetraspanin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan368.624e-2430.24tetraspanin 36 [Source:NCBI gene;Acc:437021][more]
tspan368.624e-2430.24tetraspanin 36 [Source:NCBI gene;Acc:437021][more]
tspan3b3.680e-2029.49tetraspanin 3b [Source:ZFIN;Acc:ZDB-GENE-070424-42... [more]
tspan3b3.680e-2029.49tetraspanin 3b [Source:ZFIN;Acc:ZDB-GENE-070424-42... [more]
tspan3a5.054e-1628.50tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-77... [more]
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BLAST of Tetraspanin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ephx22.906e-1628.17epoxide hydrolase 2, cytoplasmic [Source:Xenbase;A... [more]
lrrk24.336e-1529.73leucine-rich repeat kinase 2 [Source:Xenbase;Acc:X... [more]
lrrk25.913e-1529.73leucine-rich repeat kinase 2 [Source:Xenbase;Acc:X... [more]
sertad45.031e-1436.89SERTA domain containing 4 [Source:Xenbase;Acc:XB-G... [more]
trip45.746e-1425.31thyroid hormone receptor interactor 4 [Source:Xenb... [more]
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BLAST of Tetraspanin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tspan65.834e-1632.50tetraspanin 6 [Source:MGI Symbol;Acc:MGI:1926264][more]
Tspan71.627e-1528.57tetraspanin 7 [Source:MGI Symbol;Acc:MGI:1298407][more]
Tspan71.968e-1535.45tetraspanin 7 [Source:MGI Symbol;Acc:MGI:1298407][more]
Tspan62.315e-1542.22tetraspanin 6 [Source:MGI Symbol;Acc:MGI:1926264][more]
Tspan33.495e-1528.17tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098][more]
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BLAST of Tetraspanin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6NWG0|TSN36_DANRE6.510e-2330.24Tetraspanin-36 OS=Danio rerio OX=7955 GN=tspan36 P... [more]
sp|O70401|TSN6_MOUSE1.073e-1533.13Tetraspanin-6 OS=Mus musculus OX=10090 GN=Tspan6 P... [more]
sp|Q32KU6|TSN6_BOVIN1.503e-1531.88Tetraspanin-6 OS=Bos taurus OX=9913 GN=TSPAN6 PE=2... [more]
sp|Q3SZR9|TSN3_BOVIN5.827e-1528.17Tetraspanin-3 OS=Bos taurus OX=9913 GN=TSPAN3 PE=2... [more]
sp|Q62283|TSN7_MOUSE1.138e-1428.57Tetraspanin-7 OS=Mus musculus OX=10090 GN=Tspan7 P... [more]
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BLAST of Tetraspanin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GIP34.074e-2938.68Tetraspanin OS=Macrostomum lignano OX=282301 GN=BO... [more]
A0A3Q3FLQ92.400e-2230.13Tetraspanin OS=Labrus bergylta OX=56723 PE=3 SV=1[more]
A0A1S3JM912.882e-2130.37Tetraspanin OS=Lingula unguis OX=7574 GN=LOC106174... [more]
A0A1I8FUB09.835e-2146.62Tetraspanin OS=Macrostomum lignano OX=282301 PE=3 ... [more]
A0A195ELC83.499e-2031.88Tetraspanin OS=Trachymyrmex cornetzi OX=471704 GN=... [more]
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BLAST of Tetraspanin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan361.676e-2332.20tetraspanin 36 [Source:NCBI gene;Acc:437021][more]
tspan369.984e-2332.67tetraspanin 36 [Source:NCBI gene;Acc:437021][more]
cd638.946e-1828.57CD63 molecule [Source:NCBI gene;Acc:103032697][more]
cd632.564e-1728.57CD63 molecule [Source:NCBI gene;Acc:103032697][more]
tspan3a4.454e-1628.64tetraspanin 3 [Source:NCBI gene;Acc:103046031][more]
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BLAST of Tetraspanin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan3a8.662e-1730.13tetraspanin 3a [Source:ZFIN;Acc:ZDB-GENE-030131-77... [more]
ENSPMAT00000009492.14.500e-1626.85pep scaffold:Pmarinus_7.0:GL476618:258874:270129:-... [more]
tspan178.017e-1527.84tetraspanin 17 [Source:ZFIN;Acc:ZDB-GENE-030131-36... [more]
tspan4a2.339e-1426.28tetraspanin 4a [Source:ZFIN;Acc:ZDB-GENE-040718-38... [more]
ENSPMAT00000005284.14.805e-1226.19pep scaffold:Pmarinus_7.0:GL480552:16638:25636:-1 ... [more]
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BLAST of Tetraspanin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Tetraspanin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO308372.927e-1732.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO398463.190e-1533.98Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475921.536e-1428.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO343092.433e-1428.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO475939.086e-1326.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Tetraspanin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tspan3a4.155e-1928.64tetraspanin-3 [Source:NCBI gene;Acc:101170088][more]
tspan367.591e-1927.16tetraspanin-36 [Source:NCBI gene;Acc:101167371][more]
tspan3b1.307e-1527.70tetraspanin-3 [Source:NCBI gene;Acc:101165292][more]
cd631.746e-1530.43CD63 molecule [Source:NCBI gene;Acc:101174188][more]
tspan7b6.914e-1530.00tetraspanin 7 [Source:NCBI gene;Acc:101163366][more]
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BLAST of Tetraspanin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000044356.12.200e-143100.00SMESG000044356.1[more]
SMESG000063435.15.048e-1234.95SMESG000063435.1[more]
SMESG000043835.15.910e-1126.90SMESG000043835.1[more]
SMESG000021802.11.533e-930.69SMESG000021802.1[more]
SMESG000043678.11.878e-924.18SMESG000043678.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025558 ID=SMED30025558|Name=Tetraspanin|organism=Schmidtea mediterranea sexual|type=transcript|length=939bp
TATATCTAACAAACACATTTTGAGAAAATTATTATAATGGGTAGTAAAAC
AGCAACAAAATTGATTTTACTACTTGGTTTATTAGTGATACTTGCTACTT
CAGCAGTGTTTATTTTCCTCGGATCATATATTATTCACATATCAGGCACT
ATTAGTGATCTATATAAATCAACTCATGTTCTAATCCCAACAATAGTTAT
CTTGTCAGTTGGGGTTATTTTAGTGCTTTTAGTGTTAATTGGATTTTTCG
GTTGTATAATGGAGAAGAAAACATTGTTGGTAATATTTTTCACTCTATTG
TGCTTGGTTTTCCTATTTGAATTGTCTGCATTAACAATGGGCTTAGTTTT
TAAGTATAAAATAAAAACTACAATTGACAAACAATTATATAAATTATTGA
AATTTTACTCAACTGAAGTTAGTTTAAGAAAAGAAATTGATTACATTCAA
TCCACTTTGCAATGCTGCGGAGTGCAGAACTATACGGATTGGGAAATGTA
CAACAATTCAATTCCCGATTCGTGCTGCCGAAACATGAAGTGCAAACCTG
TACTGTCCTCCACACAGACAACCATCTCACCTGACGCGTACGAACCGTAT
ATAATTGGTTGTTCAGAAACTGTTGAAAAACTCATCCAACACAAATTTGT
TTACATAATTTTGATCTTGATTTCTGTCATTGCATTGCAAGTAATCAGTC
TGGTGGCTTCCTGTTGCATCATCCGCCACAGGAGCTCATCATCATCGGAT
TACCAGCCATTCAACAACCGATATAATATCTAATGTCAAACTGAATATCA
TTTATTTGTATCTCATTCACGCTCTCTGATTTCATTAATCATTTTGGAAT
TCACAGCATTTTGTCATTCTCACTTGTTTTACTACTGTGTACATGCCATT
TGTCAACGTTAAATATATTTCCGGTCTTTTGAAAAAAAA
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protein sequence of SMED30025558-orf-1

>SMED30025558-orf-1 ID=SMED30025558-orf-1|Name=SMED30025558-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=249bp
MGSKTATKLILLLGLLVILATSAVFIFLGSYIIHISGTISDLYKSTHVLI
PTIVILSVGVILVLLVLIGFFGCIMEKKTLLVIFFTLLCLVFLFELSALT
MGLVFKYKIKTTIDKQLYKLLKFYSTEVSLRKEIDYIQSTLQCCGVQNYT
DWEMYNNSIPDSCCRNMKCKPVLSSTQTTISPDAYEPYIIGCSETVEKLI
QHKFVYIILILISVIALQVISLVASCCIIRHRSSSSSDYQPFNNRYNI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR000301Tetraspanin
IPR018499Tetraspanin/Peripherin
IPR008952Tetraspanin_EC2_sf
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0005887integral component of plasma membrane
GO:0016020membrane
Vocabulary: biological process
TermDefinition
GO:0007166cell surface receptor signaling pathway
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000301TetraspaninPRINTSPR00259TMFOURcoord: 75..103
score: 30.74
coord: 206..232
score: 17.1
coord: 48..74
score: 22.85
IPR000301TetraspaninPIRSFPIRSF002419Tetraspanincoord: 2..244
e-value: 3.4E-34
score: 115.7
IPR008952Tetraspanin, EC2 domain superfamilyGENE3DG3DSA:1.10.1450.10coord: 104..181
e-value: 1.5E-14
score: 55.6
IPR008952Tetraspanin, EC2 domain superfamilySUPERFAMILYSSF48652Tetraspanincoord: 104..203
IPR018499Tetraspanin/PeripherinPFAMPF00335Tetraspanincoord: 8..231
e-value: 1.4E-35
score: 123.1
NoneNo IPR availablePANTHERPTHR19282TETRASPANINcoord: 6..243
NoneNo IPR availablePANTHERPTHR19282:SF120TETRASPANIN-36coord: 6..243
NoneNo IPR availableTMHMMTMhelixcoord: 79..101
NoneNo IPR availableTMHMMTMhelixcoord: 13..35
NoneNo IPR availableTMHMMTMhelixcoord: 50..72
NoneNo IPR availableTMHMMTMhelixcoord: 207..229