Protein kinase, putative

Overview


Name	Protein kinase, putative
Smed ID	SMED30025494
Length (bp)	2646

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein kinase, putative (SMED30025494) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein kinase, putative (SMED30025494) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein kinase, putative (SMED30025494) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein kinase, putative (SMED30025494) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025494

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30025494	SMESG000062960.1	SmedASXL_019834	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30025494	SMESG000062960.1	SmedASXL_019834	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Protein kinase, putative vs. Ensembl Human
Match: TEX14 (testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737])

HSP 1 Score: 115.161 bits (287), Expect = 2.154e-25
Identity = 109/424 (25.71%), Postives = 192/424 (45.28%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQN-------LFKNFKLHL----SIPNNPISLPHRKNSIL--NNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSME-----ISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G++ +FVAA     + V  L+  G+DPN    +G+T +HAAA+  N  +L  L+++GGDLRL +  G  P    +    + S +I +F Q        + + F   L      P   +  P     ++  N     NR  +  ++S    +  GFG ++    T    + S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++L         R  ++L    I E      LRHP +L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++H QG +H S+ S+ V++++    +L N E  +E     +  D  +  L +Q +N             W APE++  K     S DIYS ++++ E  T  IP
Sbjct:   49 VDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKFYLTGATQMAYLGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLL----IAEQEHSSKLRHPYLLQLMAVCLSQD----LEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYN-------------WAAPEVILQKAATVKS-DIYSFSMIMQEILTDDIP 449

[Close]

BLAST of Protein kinase, putative vs. Ensembl Human
Match: TEX14 (testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737])

HSP 1 Score: 115.161 bits (287), Expect = 2.259e-25
Identity = 109/424 (25.71%), Postives = 192/424 (45.28%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQN-------LFKNFKLHL----SIPNNPISLPHRKNSIL--NNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSME-----ISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G++ +FVAA     + V  L+  G+DPN    +G+T +HAAA+  N  +L  L+++GGDLRL +  G  P    +    + S +I +F Q        + + F   L      P   +  P     ++  N     NR  +  ++S    +  GFG ++    T    + S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++L         R  ++L    I E      LRHP +L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++H QG +H S+ S+ V++++    +L N E  +E     +  D  +  L +Q +N             W APE++  K     S DIYS ++++ E  T  IP
Sbjct:   49 VDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKFYLTGATQMAYLGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLL----IAEQEHSSKLRHPYLLQLMAVCLSQD----LEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYN-------------WAAPEVILQKAATVKS-DIYSFSMIMQEILTDDIP 449

[Close]

BLAST of Protein kinase, putative vs. Ensembl Human
Match: TEX14 (testis expressed 14, intercellular bridge forming factor [Source:HGNC Symbol;Acc:HGNC:11737])

HSP 1 Score: 108.997 bits (271), Expect = 2.104e-23
Identity = 109/430 (25.35%), Postives = 192/430 (44.65%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQN-------LFKNFKLHL----SIPNNPISLPHRKNSIL--NNLQKINRNNQHKIVSPYFTFQSGFG------NYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSME-----ISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G++ +FVAA     + V  L+  G+DPN    +G+T +HAAA+  N  +L  L+++GGDLRL +  G  P    +    + S +I +F Q        + + F   L      P   +  P     ++  N     NR  +  ++S    +  GFG       ++    T    + S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++L         R  ++L    I E      LRHP +L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++H QG +H S+ S+ V++++    +L N E  +E     +  D  +  L +Q +N             W APE++  K     S DIYS ++++ E  T  IP
Sbjct:   49 VDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKAMPWFQFYLTGATQMAYLGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLL----IAEQEHSSKLRHPYLLQLMAVCLSQD----LEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYN-------------WAAPEVILQKAATVKS-DIYSFSMIMQEILTDDIP 455

[Close]

BLAST of Protein kinase, putative vs. Ensembl Human
Match: TNNI3K (TNNI3 interacting kinase [Source:HGNC Symbol;Acc:HGNC:19661])

HSP 1 Score: 82.0333 bits (201), Expect = 2.591e-15
Identity = 102/458 (22.27%), Postives = 187/458 (40.83%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            C +   I L+    D N+ N      +G+T LH+A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K     +P N  S P    S   + + L KI    + K  +     ++G  ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  D   F +  Q I      GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++
Sbjct:  313 CTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADILLLRAGLPSHFHLQ------LSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVIQFVGACLN-DPSQFAIVTQYI----SGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP------------GNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLIRGWNACPEGRPEFSEV 715

[Close]

BLAST of Protein kinase, putative vs. Ensembl Human
Match: FPGT-TNNI3K (FPGT-TNNI3K readthrough [Source:HGNC Symbol;Acc:HGNC:42952])

HSP 1 Score: 82.0333 bits (201), Expect = 2.903e-15
Identity = 102/458 (22.27%), Postives = 187/458 (40.83%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            C +   I L+    D N+ N      +G+T LH+A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K     +P N  S P    S   + + L KI    + K  +     ++G  ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  D   F +  Q I      GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++
Sbjct:  427 CTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADILLLRAGLPSHFHLQ------LSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVIQFVGACLN-DPSQFAIVTQYI----SGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP------------GNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLIRGWNACPEGRPEFSEV 829

[Close]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Match: F59A3.8 (Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;Acc:P91360])

HSP 1 Score: 68.5514 bits (166), Expect = 1.264e-11
Identity = 60/248 (24.19%), Postives = 108/248 (43.55%), Query Frame = 3

Query:  783 SDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSI-KQDPSQRPKLCDIQYEISNLKKSI 1520
            +D  T     + + E  I+  L HPNVL   GV ++ +  L+ M      E C NG++  YL   ++     ++I  +      + ++HSQ I+H  +    + L  + + K+ +F    E++             + Y    +     ++LAPE L + F+  P  D++S   VIWE Y  G  PH  K  + +  +       +LS   PE L +L+ + +   DP  R  +  I   +   +K++
Sbjct:  350 ADSVTRDQVEELLHETRIMRKLDHPNVLRSYGVAVLREP-LYLM-----IELCSNGALREYLKENHKTITLADKINFVLGSARGVAYLHSQRILHRDLAVRNILLTEDKTPKVSDF-GLAELT-------------DRYEMKEHCKIPVRYLAPETL-ELFIFTPKTDVFSFGCVIWEIYENGQQPHDGKNAQTIRAQVKKREFLKLSSSAPEALRRLVAEKVFVADPENRCSMTSIVQCVETAEKTV 576

[Close]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Match: vab-1 (Ephrin receptor 1 [Source:UniProtKB/Swiss-Prot;Acc:O61460])

HSP 1 Score: 62.3882 bits (150), Expect = 1.555e-9
Identity = 60/250 (24.00%), Postives = 104/250 (41.60%), Query Frame = 3

Query:  813 QFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPE-ILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESD 1547
            +F+ EA I+G   HPNV+ L+GV    +  +   +Y        NGS+  +L N +Q+    +     E+L  +   + ++   G VH  + +  V L  E   K+ +F  S  +  +    +            N      +W APE I   KF   PS D++S  +VIWE  + G  P+ + T + +I      +        P  L ++ Q   K +  +RP    +   ++   K I +   +E D
Sbjct:  761 EFLTEATIMGQFSHPNVIRLIGVVTSAEPVMIVAEYMA------NGSLDQFLRNTDQRGEKVHWEKITEMLYGIASGMKYLTDMGYVHRDLAARNVLLDMELRCKIADFGLSRGVRSEGSSVEPEYTT-------NGGKIPVRWTAPEAITHRKFT--PSSDVWSFGVVIWEVCSFGERPYWDWTNQKVISEVMIGYRLPPPMDCPMGLYRIAQWCWKMERHERPTFTQL---LATFHKYILQPTLIEHD 992

[Close]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Match: lin-45 (Raf homolog serine/threonine-protein kinase [Source:UniProtKB/Swiss-Prot;Acc:Q07292])

HSP 1 Score: 61.6178 bits (148), Expect = 1.987e-9
Identity = 54/225 (24.00%), Postives = 103/225 (45.78%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQNQ--QFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSG-KLGNFENSMEISFDDKKSQLRSQQW--NSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP-------KLCDIQYEISNLKKSINESLHLES 1544
            I + C+  S++ ++H Q    +F     I+IL  V   ++++HS+ I+H  + ++ ++L+++ S  K+G+F  +               +W  N          +  W+APE+++  D     P  D+YS  I ++E  +  +P+ N   R+ I     + Y  P   ++    P+++LKL    I  D ++RP       +L DI        +S    LHL+S
Sbjct:  552 ITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATV-----------KTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHLDS 765

[Close]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Match: lin-45 (Raf homolog serine/threonine-protein kinase [Source:UniProtKB/Swiss-Prot;Acc:Q07292])

HSP 1 Score: 61.6178 bits (148), Expect = 2.005e-9
Identity = 54/225 (24.00%), Postives = 103/225 (45.78%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQNQ--QFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSG-KLGNFENSMEISFDDKKSQLRSQQW--NSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP-------KLCDIQYEISNLKKSINESLHLES 1544
            I + C+  S++ ++H Q    +F     I+IL  V   ++++HS+ I+H  + ++ ++L+++ S  K+G+F  +               +W  N          +  W+APE+++  D     P  D+YS  I ++E  +  +P+ N   R+ I     + Y  P   ++    P+++LKL    I  D ++RP       +L DI        +S    LHL+S
Sbjct:  508 ITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATV-----------KTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHLDS 721

[Close]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Match: lin-45 (Raf homolog serine/threonine-protein kinase [Source:UniProtKB/Swiss-Prot;Acc:Q07292])

HSP 1 Score: 61.6178 bits (148), Expect = 2.072e-9
Identity = 54/225 (24.00%), Postives = 103/225 (45.78%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQNQ--QFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSG-KLGNFENSMEISFDDKKSQLRSQQW--NSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP-------KLCDIQYEISNLKKSINESLHLES 1544
            I + C+  S++ ++H Q    +F     I+IL  V   ++++HS+ I+H  + ++ ++L+++ S  K+G+F  +               +W  N          +  W+APE+++  D     P  D+YS  I ++E  +  +P+ N   R+ I     + Y  P   ++    P+++LKL    I  D ++RP       +L DI        +S    LHL+S
Sbjct:  520 ITQWCEGSSLYRHIHVQEPRVEFEMGAIIDILKQVSLGMNYLHSKNIIHRDLKTNNIFLMDDMSTVKIGDFGLATV-----------KTKWTVNGGQQQQQPTGSILWMAPEVIRMQDDNPYTPQSDVYSFGICMYEILSSHLPYSNINNRDQILFMVGRGYLRPDRSKIRHDTPKSMLKLYDNCIMFDRNERPVFGEVLERLRDIILPKLTRSQSAPNVLHLDS 733

[Close]

BLAST of Protein kinase, putative vs. Ensembl Fly
Match: Raf (gene:FBgn0003079 transcript:FBtr0070401)

HSP 1 Score: 61.2326 bits (147), Expect = 3.828e-9
Identity = 42/201 (20.90%), Postives = 94/201 (46.77%), Query Frame = 3

Query:  939 CDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSI--DIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSI 1520
            C+  S++ ++H    +F     I+I   V   +D++H++ I+H  + S+ ++L  + S K+G+F           K+     +W+     N    +  W+APE+++ + +   S   D+Y+  IV++E     +P+ + + ++ I     +    P   ++    P+ L +L +  IK  P  RP    +   + N+ +++
Sbjct:  504 CEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDF------GLATAKT-----RWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTL 693

[Close]

BLAST of Protein kinase, putative vs. Ensembl Fly
Match: Raf (gene:FBgn0003079 transcript:FBtr0344007)

HSP 1 Score: 61.2326 bits (147), Expect = 3.828e-9
Identity = 42/201 (20.90%), Postives = 94/201 (46.77%), Query Frame = 3

Query:  939 CDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSI--DIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSI 1520
            C+  S++ ++H    +F     I+I   V   +D++H++ I+H  + S+ ++L  + S K+G+F           K+     +W+     N    +  W+APE+++ + +   S   D+Y+  IV++E     +P+ + + ++ I     +    P   ++    P+ L +L +  IK  P  RP    +   + N+ +++
Sbjct:  504 CEGSSLYKHVHVSETKFKLNTLIDIGRQVAQGMDYLHAKNIIHRDLKSNNIFLHEDLSVKIGDF------GLATAKT-----RWSGEKQANQPTGSILWMAPEVIRMQELNPYSFQSDVYAFGIVMYELLAECLPYGHISNKDQILFMVGRGLLRPDMSQVRSDAPQALKRLAEDCIKYTPKDRPLFRPLLNMLENMLRTL 693

[Close]

BLAST of Protein kinase, putative vs. Ensembl Fly
Match: Eph (gene:FBgn0025936 transcript:FBtr0301285)

HSP 1 Score: 61.2326 bits (147), Expect = 4.514e-9
Identity = 56/250 (22.40%), Postives = 103/250 (41.20%), Query Frame = 3

Query:  816 FIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTF--KWLAPEILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKES 1556
            F+ EA+I+G   HPNV+ L GV    +  +   +Y       +NGS+  +L   + +F     I +L  +   + ++     VH  + +  V +  +   K+ +F  S EI              N+ + Y         +W APE +  +     S D++S  +V+WE  + G  P+ N + +++I+     +        PE L +L+    ++  + RP    I   + NL +     L      ES
Sbjct:  756 FLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYM------ENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIE-------------NASDAYTTRGGKIPVRWTAPEAIAFRKFTSAS-DVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPES 985

[Close]

BLAST of Protein kinase, putative vs. Ensembl Fly
Match: Eph (gene:FBgn0025936 transcript:FBtr0089083)

HSP 1 Score: 61.2326 bits (147), Expect = 4.571e-9
Identity = 56/250 (22.40%), Postives = 103/250 (41.20%), Query Frame = 3

Query:  816 FIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTF--KWLAPEILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKES 1556
            F+ EA+I+G   HPNV+ L GV    +  +   +Y       +NGS+  +L   + +F     I +L  +   + ++     VH  + +  V +  +   K+ +F  S EI              N+ + Y         +W APE +  +     S D++S  +V+WE  + G  P+ N + +++I+     +        PE L +L+    ++  + RP    I   + NL +     L      ES
Sbjct:  740 FLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYM------ENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIE-------------NASDAYTTRGGKIPVRWTAPEAIAFRKFTSAS-DVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPES 969

[Close]

BLAST of Protein kinase, putative vs. Ensembl Fly
Match: Eph (gene:FBgn0025936 transcript:FBtr0089082)

HSP 1 Score: 61.2326 bits (147), Expect = 4.614e-9
Identity = 56/250 (22.40%), Postives = 103/250 (41.20%), Query Frame = 3

Query:  816 FIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTF--KWLAPEILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKES 1556
            F+ EA+I+G   HPNV+ L GV    +  +   +Y       +NGS+  +L   + +F     I +L  +   + ++     VH  + +  V +  +   K+ +F  S EI              N+ + Y         +W APE +  +     S D++S  +V+WE  + G  P+ N + +++I+     +        PE L +L+    ++  + RP    I   + NL +     L      ES
Sbjct:  773 FLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYM------ENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIE-------------NASDAYTTRGGKIPVRWTAPEAIAFRKFTSAS-DVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPES 1002

[Close]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040805-1])

HSP 1 Score: 77.7962 bits (190), Expect = 4.104e-14
Identity = 51/224 (22.77%), Postives = 106/224 (47.32%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            Q   + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  574 QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGALPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIHRSASEPSLNRA 786

[Close]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040805-1])

HSP 1 Score: 77.7962 bits (190), Expect = 4.141e-14
Identity = 51/224 (22.77%), Postives = 106/224 (47.32%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            Q   + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  534 QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGALPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIHRSASEPSLNRA 746

[Close]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Match: tnni3k (TNNI3 interacting kinase [Source:ZFIN;Acc:ZDB-GENE-081104-399])

HSP 1 Score: 77.411 bits (189), Expect = 4.572e-14
Identity = 94/428 (21.96%), Postives = 184/428 (42.99%), Query Frame = 3

Query:  252 EGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIP-NFPCGL----YTKVISKN----WHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNF-ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            +G+T LH+A +  ++RL+Q L+++GGD+ LV  D  R          S   KD +  L   ++                ++I+  L+   R       + Y +   G G+Y     ++   +  IK +   K     L++ +P NF   L    + ++I        +      KI+++   + N    +++  T+ F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F E+   +S D+    +  Q  N            +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P +RP+  ++
Sbjct:  339 DGHTGLHSACFHGHIRLVQFLLDNGGDMNLVACDPSR----------SSGEKDEQTCLMWAYE-------------KGHDAIVTLLKHYKRPQDDSPCNEY-SQPGGDGSYV----SVPSPLGKIKSMTKEKADVLLLRASLPSNFHLQLSELEFNEIIGSGSFGKVYKGKCRNKIVAIKRYRPNTYCSKSD--TDMFCREVSILCRLNHPCVIQFVGACL--DDP---SQFAIVTQYVSGGSLFSLLHEQKRIIDLQSKLIIAIDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLLSVDE--DNMTKQPGN-----------LRWMAPEVFTQCTRYTVKADMFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHVRP---PIGYSIPKPISALLMRGWNVCPEERPEFSEV 715

[Close]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Match: raf1a (Raf-1 proto-oncogene, serine/threonine kinase a [Source:ZFIN;Acc:ZDB-GENE-990415-41])

HSP 1 Score: 70.0922 bits (170), Expect = 7.867e-12
Identity = 56/238 (23.53%), Postives = 104/238 (43.70%), Query Frame = 3

Query:  903 LFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI-------QYEISNLKKSINE-SLHLESDKE 1553
            L  M Y T      + + C+  S++ +LH     F     I+I       +D++H++ I+H  + S+ ++L    + K+G+F  +               +W+          +  W+APE+++  D        D+YS  IV++E  TG +P+     R+ I     + Y +P   +L  R P+ + +L+   IK+   +RP    I       Q+ +  + +S +E SLH  S  E
Sbjct:  413 LLFMGYMTKGNLAIVTQWCEGSSLYKHLHVLETNFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATV-----------KARWSGSQQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMTGELPYSQIGNRDQIIFMVGRGYLSPDLSKLYKRCPKAMKRLVADCIKKSKDERPLFPQILSSIELLQHSLPKINRSASEPSLHRASQSE 639

[Close]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Match: raf1a (Raf-1 proto-oncogene, serine/threonine kinase a [Source:ZFIN;Acc:ZDB-GENE-990415-41])

HSP 1 Score: 70.0922 bits (170), Expect = 8.757e-12
Identity = 56/238 (23.53%), Postives = 104/238 (43.70%), Query Frame = 3

Query:  903 LFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI-------QYEISNLKKSINE-SLHLESDKE 1553
            L  M Y T      + + C+  S++ +LH     F     I+I       +D++H++ I+H  + S+ ++L    + K+G+F  +               +W+          +  W+APE+++  D        D+YS  IV++E  TG +P+     R+ I     + Y +P   +L  R P+ + +L+   IK+   +RP    I       Q+ +  + +S +E SLH  S  E
Sbjct:  402 LLFMGYMTKGNLAIVTQWCEGSSLYKHLHVLETNFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATV-----------KARWSGSQQVEQPSGSILWMAPEVIRMQDNNPYSFQSDVYSYGIVLFELMTGELPYSQIGNRDQIIFMVGRGYLSPDLSKLYKRCPKAMKRLVADCIKKSKDERPLFPQILSSIELLQHSLPKINRSASEPSLHRASQSE 628

[Close]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Match: MGC115642 (hypothetical protein MGC115642 [Source:Xenbase;Acc:XB-GENE-5791624])

HSP 1 Score: 93.5893 bits (231), Expect = 8.125e-19
Identity = 108/470 (22.98%), Postives = 208/470 (44.26%), Query Frame = 3

Query:  201 MVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQNLFKNFK-LHLSIPNNPISLPHRKNSILNN---LQKINRNNQHKIVSPYFTFQS---------GFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILN---NVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPK-----LCDIQYEISNLKKSINESLHLE 1541
            MV  LL  G++PN   ++ +T +HAAA+  N   L +L+++GGDLRL + D   P    ++   KN+ ++ +F +    + + L    P+  +      + +++N   +  I++ +  K +  Y  +           G+G  +  N      ++ I  I   +DL       + +F  G Y  + +  W  T V++K   L+   +N          +  I E   +  L HP++L L+ V L  D +   +    +FER   G++++ LH +  +F   +   ILN    VIDAL F+H +G +H S  SH + ++      L +++         K  ++R+      + +      ++W APE++  K +   S D++S  +V+ ES T  +P        +     +  +  +  RI +   K++   I+     R       L  ++ +I   +KS +E+L +E
Sbjct:    1 MVDLLLRYGSNPNHRCYDWSTPVHAAAFSGNQWSLSMLIDAGGDLRLHDQDCRNPYFWALLAGKKNNAQMIEFIERCTAHMQALIQCFPHKALRKVDSSSILIHNPSLIYLISQGSAEKPLIKYCKYGGILTNAISSFGYGKLYFTNDNHLSCMAYIPYI-EERDLVQGHDKPVFSFSTGHYMTMTNLMWGYTEVTVK--ELMSTHQNCGKLH---FADLLIAEQEYMSKLHHPHILQLLAVCLSHDLEKTCL----VFERVMFGTLYSILHERRTEFPVLHMETILNILLQVIDALIFVHWRGFIHCSFSSHAINIILPGLVTLSSWQKGSS----SKDGKVRTD----VSHFPIPKYLYRWSAPEVILGKTISTKS-DLFSFCVVMQESLTDTLPWDGLDCFAVKNAVISGHNLAVDLRIAKPYDKIVSTGIQAMAKDRTMSLQDILWKLRKDIEESRKSASETLDIE 451

[Close]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Match: tnni3k (TNNI3 interacting kinase [Source:NCBI gene;Acc:100495062])

HSP 1 Score: 77.7962 bits (190), Expect = 5.770e-14
Identity = 103/471 (21.87%), Postives = 194/471 (41.19%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNF-ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSIN 1523
            C +   + L+    D N+ N      +G+T LH A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K      P N  S P    S   + + L KI    + K  +     ++   ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +  I+H  + SH + L  +    + +F E+   +S D+    +  Q  N            +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++   +S L++ ++
Sbjct:  313 CTYGKNMELVKFLLDQNVLNINHQGRDGHTGLHCACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDESPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADVLLLRASLPSHFHLQ------MSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCRLNHPCVIQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRNLDLQSKLIIAVDVAKGMEYLHNLTYPIIHRDLNSHNILLYEDGHAVVADFGESRFLLSLDE--DNMTKQPGN-----------LRWMAPEVFSQCTRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLMRGWNACPEGRPEFSEV---VSKLEECLS 724

[Close]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Match: tnni3k (TNNI3 interacting kinase [Source:NCBI gene;Acc:100495062])

HSP 1 Score: 77.411 bits (189), Expect = 7.230e-14
Identity = 103/471 (21.87%), Postives = 194/471 (41.19%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNF-ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSIN 1523
            C +   + L+    D N+ N      +G+T LH A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K      P N  S P    S   + + L KI    + K  +     ++   ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +  I+H  + SH + L  +    + +F E+   +S D+    +  Q  N            +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++   +S L++ ++
Sbjct:  313 CTYGKNMELVKFLLDQNVLNINHQGRDGHTGLHCACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDESPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADVLLLRASLPSHFHLQ------MSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCRLNHPCVIQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRNLDLQSKLIIAVDVAKGMEYLHNLTYPIIHRDLNSHNILLYEDGHAVVADFGESRFLLSLDE--DNMTKQPGN-----------LRWMAPEVFSQCTRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLMRGWNACPEGRPEFSEV---VSKLEECLS 724

[Close]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Match: tnni3k (TNNI3 interacting kinase [Source:NCBI gene;Acc:100495062])

HSP 1 Score: 77.0258 bits (188), Expect = 9.714e-14
Identity = 103/471 (21.87%), Postives = 194/471 (41.19%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNF-ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSIN 1523
            C +   + L+    D N+ N      +G+T LH A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K      P N  S P    S   + + L KI    + K  +     ++   ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +  I+H  + SH + L  +    + +F E+   +S D+    +  Q  N            +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++   +S L++ ++
Sbjct:  313 CTYGKNMELVKFLLDQNVLNINHQGRDGHTGLHCACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDESPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADVLLLRASLPSHFHLQ------MSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCRLNHPCVIQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRNLDLQSKLIIAVDVAKGMEYLHNLTYPIIHRDLNSHNILLYEDGHAVVADFGESRFLLSLDE--DNMTKQPGN-----------LRWMAPEVFSQCTRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLMRGWNACPEGRPEFSEV---VSKLEECLS 724

[Close]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Match: BRAF (B-Raf proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:779570])

HSP 1 Score: 76.2554 bits (186), Expect = 1.508e-13
Identity = 50/224 (22.32%), Postives = 106/224 (47.32%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            Q + + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+++  D        D+Y+  IV++E  TG +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  529 QLRLVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRMQDNNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDFSKVRSNCPKAMKRLMADCLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRA 741

[Close]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Match: Tex14 (testis expressed gene 14 [Source:MGI Symbol;Acc:MGI:1933227])

HSP 1 Score: 119.398 bits (298), Expect = 8.606e-27
Identity = 115/419 (27.45%), Postives = 193/419 (46.06%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQNLFKNFKL-----------HLSIPNNPISLPHRKNSILNNLQKINRNNQHK--IVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G+S +FVAA     ++V  L+  G+DPN    +G+T +HAAA+  N  +L  L+ +GGDLRL +  G  P    +      S ++ +F Q    + K             +  P   I  P    S++      + N Q K  I+S    +  GFG ++  +        S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++ L  + + S  R   L +  I E     +LRHPN+L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  V DAL ++HS+G +H S+ S+ V++V+    +L N E   E S D    +  ++       YN       W APE++  K     S DIYS +++I E  T  IP
Sbjct:   49 VDAVNTQGQSALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGDLRLHDEKGRNPQAWALTAGKDRSTQMVEFMQRCTSHMKAIIQGFSYDLLKKIDSPQRLIGSPPWFGSLIQGSPNSSPNRQLKPGIISAQNIYSFGFGKFYLTSGMQLTYPGSLPVIGEKEVVQADDEPTF-SFFSGPYMVMTNLVWNRSRVTVKELN-LPTRPHCSRLR---LADLLIAEQEHSSNLRHPNLLQLMAVCLSRD----LEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQVADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYLTE-SQDSGAHRNVTRMPLPTQLYN-------WAAPEVVLQKAATVKS-DIYSFSVIIQEILTDSIP 449

[Close]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Match: Tnni3k (TNNI3 interacting kinase [Source:MGI Symbol;Acc:MGI:2443276])

HSP 1 Score: 79.337 bits (194), Expect = 1.211e-14
Identity = 95/458 (20.74%), Postives = 187/458 (40.83%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPN--------------FPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHS--QGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            C +   I L+    D N  N      +G+T LH+A Y  ++RL+Q L+++G D+ LV  D  R          S   KD +  L   ++              + +  +  L K  +  Q ++    ++   G G+Y     ++   +  IK +   K     L++++P+                 G + KV      +     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++HS  Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++
Sbjct:  312 CTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSR----------SSGEKDEQTCLMWAYE--------------KGHDAIVTLLKHYKRPQDELPCNEYSQPGGDGSYV----SVPSPLGKIKSMTKEKADVLLLRAELPSRFHLQLSEIEFHEIIGSGSFGKVYKGRCRN-----KIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVVQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP------------GNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLMRGWNACPEGRPEFSEV 714

[Close]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Match: Braf (Braf transforming gene [Source:MGI Symbol;Acc:MGI:88190])

HSP 1 Score: 78.9518 bits (193), Expect = 1.800e-14
Identity = 51/224 (22.77%), Postives = 107/224 (47.77%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            Q   + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+++  DK       D+Y+  IV++E  TG +P+ N   R+ I     + Y +P   ++    P+ + +L+ + +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  508 QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRA 720

[Close]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Match: Braf (Braf transforming gene [Source:MGI Symbol;Acc:MGI:88190])

HSP 1 Score: 78.9518 bits (193), Expect = 1.942e-14
Identity = 51/224 (22.77%), Postives = 107/224 (47.77%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            Q   + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+++  DK       D+Y+  IV++E  TG +P+ N   R+ I     + Y +P   ++    P+ + +L+ + +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  561 QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRA 773

[Close]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Match: Tnni3k (TNNI3 interacting kinase [Source:MGI Symbol;Acc:MGI:2443276])

HSP 1 Score: 72.7886 bits (177), Expect = 1.325e-12
Identity = 93/404 (23.02%), Postives = 165/404 (40.84%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHS--QGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            C +   I L+    D N  N      +G+T LH+A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K     +P N  S P    S   + + L KI    + K  +     ++   + F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++HS  Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP
Sbjct:  312 CTYGKNIDLVKFLLDQNAVNINHRGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADVLLLRAELPSRFHLQ------LSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVVQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHSLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP------------GNLRWMAPEVFTQCTRYTIKADVFSYALCLWELLTGEIP 663

[Close]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Match: sp|F1MJR8|TEX14_BOVIN (Inactive serine/threonine-protein kinase TEX14 OS=Bos taurus OX=9913 GN=TEX14 PE=3 SV=2)

HSP 1 Score: 121.324 bits (303), Expect = 1.499e-26
Identity = 109/421 (25.89%), Postives = 191/421 (45.37%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQNL----------FKNFKLHLSIPNNPISLPHRKNSIL--NNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLD---NTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G++ +F+AA     ++V  L+  GADPN    +G+T +HAAA+  N  +L  L+++GGDLRL +  G  P    +    + S  + +F Q            F +    +  P   IS   R   ++  N     NR  +  ++S    +  GFG ++    T    + S+ +I   + +  D +    +F  G Y  + +  W+ + V++K + L         R  ++L    I E      LRHP+VL LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++HS+G +H S+ S+ +++V+    +L N E  ME           SQ   ++     +      + W APE++  K     S DIYS ++++ E  T  IP
Sbjct:   49 VDAVNSLGQTALFIAALLGLTKLVDVLVDYGADPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDEKGRNPQTWALAAGKERSTVMVEFMQRCAAHMQAIIQGFSDLLKKIDSPQRLISGVPRFGGLMQGNPNGSPNRPPKAGVISAQNIYSFGFGKFYLTGGTQLAYLGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNGSRVTVKELHLSTHPHCSRLRMADLL----IAEQEHSSKLRHPHVLQLMAVCLSPD----LEKTRLVYERVTVGTLFSVLHERRAQFPVLHMEVIVHLLLQISDALRYLHSRGFIHRSLSSYAIHIVSTGEARLTNLEYMME-----------SQDGGAHRGLTRVPLPTQLYNWAAPEVIIQKAATVKS-DIYSFSVIVQEILTDNIP 448

[Close]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q7M6U3|TEX14_MOUSE (Inactive serine/threonine-protein kinase TEX14 OS=Mus musculus OX=10090 GN=Tex14 PE=1 SV=2)

HSP 1 Score: 119.398 bits (298), Expect = 6.020e-26
Identity = 115/419 (27.45%), Postives = 193/419 (46.06%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQNLFKNFKL-----------HLSIPNNPISLPHRKNSILNNLQKINRNNQHK--IVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G+S +FVAA     ++V  L+  G+DPN    +G+T +HAAA+  N  +L  L+ +GGDLRL +  G  P    +      S ++ +F Q    + K             +  P   I  P    S++      + N Q K  I+S    +  GFG ++  +        S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++ L  + + S  R   L +  I E     +LRHPN+L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  V DAL ++HS+G +H S+ S+ V++V+    +L N E   E S D    +  ++       YN       W APE++  K     S DIYS +++I E  T  IP
Sbjct:   49 VDAVNTQGQSALFVAALLGHVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLTAGGDLRLHDEKGRNPQAWALTAGKDRSTQMVEFMQRCTSHMKAIIQGFSYDLLKKIDSPQRLIGSPPWFGSLIQGSPNSSPNRQLKPGIISAQNIYSFGFGKFYLTSGMQLTYPGSLPVIGEKEVVQADDEPTF-SFFSGPYMVMTNLVWNRSRVTVKELN-LPTRPHCSRLR---LADLLIAEQEHSSNLRHPNLLQLMAVCLSRD----LEKIRLVYERITVGTLFSVLHERRSQFPVLHMEVIVHLLLQVADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYLTE-SQDSGAHRNVTRMPLPTQLYN-------WAAPEVVLQKAATVKS-DIYSFSVIIQEILTDSIP 449

[Close]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Match: sp|F1M5M3|TEX14_RAT (Inactive serine/threonine-protein kinase TEX14 OS=Rattus norvegicus OX=10116 GN=Tex14 PE=1 SV=2)

HSP 1 Score: 117.857 bits (294), Expect = 1.909e-25
Identity = 111/419 (26.49%), Postives = 191/419 (45.58%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQNLFKNFKL-----------HLSIPNNPISLPHRKNSILNNLQKINRNNQHK--IVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G+S +FVAA     ++V  L+  G+DPN    +G+T +HAAA+  N  +L  ++ +GGDLRL +  G  P    +      S ++ +F Q    + K             +  P   I  P     ++      + N Q K  I+S    +  GFG ++  +        S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++L         R  ++L    I E     +LRHP++L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++HS+G +H S+ S+ V++V+    +L N E  ME S D    +  ++       YN       W APE++  K     S DIYS +++I E  T  IP
Sbjct:   49 VDAVNTLGQSALFVAALLGYVKLVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKVLTAGGDLRLHDEKGRNPQAWALAAGKDRSTQMVEFMQRCASHMKAVIQGFSYDLLKKIDSPQRLIGSPPWFGGLIQGSPNSSPNRQPKPGIISAQNIYSFGFGKFYLTSGMQLTYPGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNRSRVTVKELNLPTHPHCSRLRLADLL----IAEQEHSSNLRHPSLLQLMAVCLSRD----LEKIRLVYERITVGTLFSVLHERRSQFPVLHMEMIVHLLLQIADALIYLHSRGFIHRSLSSYAVHIVSAGEARLTNLEYMME-SQDSGAHRDMTRVPLPAQLYN-------WAAPEVVLQKTATVKS-DIYSFSMIIQEILTDNIP 449

[Close]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q8IWB6|TEX14_HUMAN (Inactive serine/threonine-protein kinase TEX14 OS=Homo sapiens OX=9606 GN=TEX14 PE=1 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 1.010e-22
Identity = 109/430 (25.35%), Postives = 192/430 (44.65%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--CQMMKNTKNSEKIKDFEQN-------LFKNFKLHL----SIPNNPISLPHRKNSIL--NNLQKINRNNQHKIVSPYFTFQSGFG------NYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNR---IEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSME-----ISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIP 1337
            ++  N  G++ +FVAA     + V  L+  G+DPN    +G+T +HAAA+  N  +L  L+++GGDLRL +  G  P    +    + S +I +F Q        + + F   L      P   +  P     ++  N     NR  +  ++S    +  GFG       ++    T    + S+ +I   + +  D +    +F  G Y  + +  W+ + V++K ++L         R  ++L    I E      LRHP +L LM V L  D      + + ++ER   G++ + LH +  QF   +    + +L  + DAL ++H QG +H S+ S+ V++++    +L N E  +E     +  D  +  L +Q +N             W APE++  K     S DIYS ++++ E  T  IP
Sbjct:   49 VDAVNSLGQTALFVAALLGLRKFVDVLVDYGSDPNHRCFDGSTPVHAAAFSGNQWILSKLLDAGGDLRLHDERGQNPKTWALTAGKERSTQIVEFMQRCASHMQAIIQGFSYDLLKKIDSPQRLVYSPSWCGGLVQGNPNGSPNRLLKAGVISAQNIYSFGFGKAMPWFQFYLTGATQMAYLGSLPVIGEKEVIQADDEPTF-SFFSGPYMVMTNLVWNGSRVTVKELNLPTHPHCSRLRLADLL----IAEQEHSSKLRHPYLLQLMAVCLSQD----LEKTRLVYERITIGTLFSVLHERRSQFPVLHMEVIVHLLLQISDALRYLHFQGFIHRSLSSYAVHIISPGEARLTNLEYMLESEDRGVQRDLTRVPLPTQLYN-------------WAAPEVILQKAATVKS-DIYSFSMIMQEILTDDIP 455

[Close]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q59H18|TNI3K_HUMAN (Serine/threonine-protein kinase TNNI3K OS=Homo sapiens OX=9606 GN=TNNI3K PE=1 SV=3)

HSP 1 Score: 82.0333 bits (201), Expect = 1.244e-14
Identity = 102/458 (22.27%), Postives = 187/458 (40.83%), Query Frame = 3

Query:  189 CEFEMVIHLLSIGADPNIAN-----HEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            C +   I L+    D N+ N      +G+T LH+A Y  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K     +P N  S P    S   + + L KI    + K  +     ++G  ++F L       +S I+   I+ S       K +  N                     KI+++   + N    ++++  + F +E +IL  L HP V+  +G  L  D   F +  Q I      GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    + + IP+ +  LL +     P  RP+  ++
Sbjct:  313 CTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPQDELPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADILLLRAGLPSHFHLQ------LSEIEFHEIIGSGSFGKVYKGRCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCQLNHPCVIQFVGACLN-DPSQFAIVTQYI----SGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSLDEDNMTKQP------------GNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPISSLLIRGWNACPEGRPEFSEV 715

[Close]

BLAST of Protein kinase, putative vs. TrEMBL
Match: A0A267ECB1 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig007134g1 PE=4 SV=1)

HSP 1 Score: 195.667 bits (496), Expect = 1.176e-48
Identity = 131/466 (28.11%), Postives = 224/466 (48.07%), Query Frame = 3

Query:  108 KSCLTTHSDINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFK----WLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNK-----TYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKL 1478
            K CL      N +N  GE+ +FVA+Y+   ++V  LL  GA PN+ N +GNT LHAAA   + R++  L+ SG DL LVN+DG R    + +     +  D  +  +  F+                   L N   +    +H    P     +GFG     + +   L+  + I+  + D   D  + + ++ CG +T+++S  W S+ VS++ ++     +        ++ NQ + E     SLRHP +L +M V++             IFER   GS+ ++LH ++Q  N+  R   L  + +AL F+HS+G+VH ++ SH V+LV+ +  KLG  E ++  +    +             Y +L++ ++    WLAPE+L ++     + D+Y L +V WE +T  +PH+         R L QR +   S     R+PE+L +L+  ++  +P +RP L
Sbjct:   24 KQCLIKGLHPNAENENGETALFVASYYGHEDIVDLLLCSGAKPNLPNKQGNTPLHAAASRGHHRVMSRLISSGADLSLVNSDGKR----VADVARGRRAIDIVERKWATFQR------------------LINCGHLRPGREHW---PPGVMDTGFGPVVIADGS-PALLHGLPIVNAATDELRDDPALVRSYRCGAFTEIVSMTWRSSAVSVRQLNRHYVTKATGAYVKCLVLNQAVWEVTAASSLRHPAILTMMAVSVDTHSVHAYPIITPIFERVGLGSLFHHLHVRHQPLNDATRYAYLRQIGEALAFLHSRGVVHTALSSHAVHLVSPSLAKLGCLEYAVCTADTGPRCS-----------YASLNDCYRAVANWLAPELL-NRLPATAAADVYGLGVVAWEMWTAQVPHETAQSAADIRRRLSQRSSDWLSRWRDRRLPESLQQLVLSAVLPEPHRRPPL 451

[Close]

BLAST of Protein kinase, putative vs. TrEMBL
Match: A0A267H0D6 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig033200g1 PE=4 SV=1)

HSP 1 Score: 189.119 bits (479), Expect = 2.982e-45
Identity = 131/466 (28.11%), Postives = 224/466 (48.07%), Query Frame = 3

Query:  108 KSCLTTHSDINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFK----WLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKT-----YRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKL 1478
            K CL      N +N  GE+ +FVA+Y+   ++V  LL  GA PN+ N +GNT LHAAA   + R++  L+ SG DL LVN+DG R    + +     +  D  +  +  F+                   L N   +    +H    P     +GFG     + +   L+  + I+  + D   D  + + ++ CG +T+++S  W S+ VS++ ++     +        ++ NQ + E     SLRHP +L +M V++             IFER   GS+ ++LH ++Q  N+  R   L  + +AL F+HS+G+VH ++ SH V+LV+ +  KLG  E ++  +    +             Y +L++ ++    WLAPE+L ++     + D+Y L +V WE +T  +PH+         R L QR +   S     R+PE+L +L+  ++  +P +RP L
Sbjct:   29 KQCLIKGLHPNAENENGETALFVASYYGHEDIVDLLLCSGAKPNLPNKQGNTPLHAAASRGHHRVMSRLISSGADLSLVNSDGKR----VADVARGRRAIDIVERKWATFQR------------------LINCGHLRPGREHW---PPGVMDTGFGPVVIADGS-PALLHGLPIVNAATDELRDDPALVRSYRCGAFTEIVSMTWRSSAVSVRQLNRHYVTKATGAYVKCLVLNQAVWEVTAASSLRHPAILTMMAVSVDTHSVHAYPIITPIFERVGLGSLFHHLHVRHQPLNDATRYAYLRQIGEALAFLHSRGVVHTALSSHAVHLVSPSLAKLGCLEYAVCTADTGPRCS-----------YASLNDCYRAVANWLAPELL-NRLPATAAADVYGLGVVAWEIWTAQVPHETAQSAADIRRRLSQRSSDWLSRWRDRRLPESLQQLVLSAVLPEPHRRPPL 456

[Close]

BLAST of Protein kinase, putative vs. TrEMBL
Match: A0A226F6S1 (Inactive serine/threonine-protein kinase TEX14 OS=Folsomia candida OX=158441 GN=Fcan01_02743 PE=4 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 5.930e-32
Identity = 131/475 (27.58%), Postives = 220/475 (46.32%), Query Frame = 3

Query:  135 INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNI-ANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNS--EKIK----DFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINR------NNQHKIVSPYF---TFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNW--HSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQ-WNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFR---IPENLLKLLQQSIKQDPSQR 1469
            ++ +N+ G + +FVAA   + ++V  LL +GA+PN     EG TALH A +  +L +L+ L+  GGDLRL +++  RP        C   + T     E+I+      + N  K  +LH  + N  + +P R ++I   +++I +          KI +         +GFG  +    T    +  I  +  + D   D   K P++ CG ++  I   W    T V+ K++     +E V D          I E  +L  L+HP +L+++ +    +    ++    IFE+   GS++ +LH QN +  +    +I+  + +ALD+IH  G +H  I SH V LV +N  KLG  E +M    +  +S L S+  W   +  ++L     WLAPE+L        + D+YSL  V+WE   G +P ++     L          +L  R   IP   L +LQ  +K+   +R
Sbjct:   50 VDSRNQDGLTALFVAATLGKKDVVNTLLRLGANPNARCRPEGFTALHGACFIGSLYILRRLLIEGGDLRLSDSNRRRPEDWIEFQQCVFTRKTTRDFIERIRFCIMKKDLNEMKT-ELHDKVEN--LRVPVR-STIWKMMRRIGKMLDFGSGRSSKITTELRHSNPVSTGFGKVYFGTGTKCAQVIGIPCVTEALDFKLDSNPKAPSWICGKFSTFIPMFWNQRKTAVTSKVLRRKSVQEAVPD--------ILISELALLVRLQHPQILMILAICQEENFDSLSL----IFEKIALGSLYFFLHQQNLRMKSTFATDIIIQISEALDYIHGSGFLHCGISSHAVMLVGDNHAKLGCLEYAMPEEKNAAESFLSSRHPWLETD--SHLSVLRHWLAPEVLIGTHPHSQASDVYSLCSVMWELVVGDVPWKDHDLAKLRILLKESPGLQLQLRKDVIPPLWLSVLQVGLKRKREER 506

[Close]

BLAST of Protein kinase, putative vs. TrEMBL
Match: A0A4V3SFS2 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003728 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 1.836e-29
Identity = 101/352 (28.69%), Postives = 177/352 (50.28%), Query Frame = 3

Query:  132 DINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKD-----LTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISL-LDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTM------QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEIS 1151
            ++N  N++ E+ +FVA+YF E  ++  LL  GAD N  N +GNT LHAAAY  +   ++IL  +G D  + NN GL    + + ++N    KDF + L +  +               K S+L  L+      +H   +PY    + +G + CL    +  + SI +I +SK+     L  D+  ++      LY    SK W  T V+++ ++   D +  +  R   +  N  ++E  ++  L+HPN+L L+ V L+  D + ++      Q   ++ER   GS+H++   + +     +   I   V +AL F+HS G+VH ++  + ++L + +S KLGNFE ++E S
Sbjct:   33 NVNSVNKFNETALFVASYFGETNIICLLLEHGADVNSKNVDGNTPLHAAAYNGDRNSMRILTSAGADGSIPNNHGLTAIDVFERSQNHRPGKDFTRLLRQPEQS------------SEKTSLLERLKCHKFAKRHLRHAPYKLITTDYGRFLCLQNHPRKYMKSIPVI-DSKELLRNSLCVDVNEEV------LYASTESKRWRGTSVNIRRVTTDYDWRGQLEARLRTVFDNSIVRELKVISRLQHPNILNLLAVMLL--DPITSLELVDPTQLALVYERPSLGSLHHWTQVKLEDVPVLSAFTICRQVAEALMFLHSFGMVHCNVTPYAIHLFSLDSAKLGNFEYAVEPS 363

[Close]

BLAST of Protein kinase, putative vs. TrEMBL
Match: A0A4S2LZV7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_003728 PE=4 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 2.054e-29
Identity = 101/352 (28.69%), Postives = 177/352 (50.28%), Query Frame = 3

Query:  132 DINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKD-----LTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISL-LDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTM------QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEIS 1151
            ++N  N++ E+ +FVA+YF E  ++  LL  GAD N  N +GNT LHAAAY  +   ++IL  +G D  + NN GL    + + ++N    KDF + L +  +               K S+L  L+      +H   +PY    + +G + CL    +  + SI +I +SK+     L  D+  ++      LY    SK W  T V+++ ++   D +  +  R   +  N  ++E  ++  L+HPN+L L+ V L+  D + ++      Q   ++ER   GS+H++   + +     +   I   V +AL F+HS G+VH ++  + ++L + +S KLGNFE ++E S
Sbjct:   33 NVNSVNKFNETALFVASYFGETNIICLLLEHGADVNSKNVDGNTPLHAAAYNGDRNSMRILTSAGADGSIPNNHGLTAIDVFERSQNHRPGKDFTRLLRQPEQS------------SEKTSLLERLKCHKFAKRHLRHAPYKLITTDYGRFLCLQNHPRKYMKSIPVI-DSKELLRNSLCVDVNEEV------LYASTESKRWRGTSVNIRRVTTDYDWRGQLEARLRTVFDNSIVRELKVISRLQHPNILNLLAVMLL--DPITSLELVDPTQLALVYERPSLGSLHHWTQVKLEDVPVLSAFTICRQVAEALMFLHSFGMVHCNVTPYAIHLFSLDSAKLGNFEYAVEPS 363

[Close]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Match: ENSAMXT00000008987.2 (testis expressed 14, intercellular bridge forming factor [Source:NCBI gene;Acc:103034854])

HSP 1 Score: 99.3673 bits (246), Expect = 9.883e-21
Identity = 112/478 (23.43%), Postives = 212/478 (44.35%), Query Frame = 3

Query:  132 DINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNT--KNSEKIKDFEQNLFKNF---------KLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFG-NYFCLNKTIK--GLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILT--NQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQF---NNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLG--NFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP-KLCDIQYEI 1499
            D++ +N  G++ +F A+      +V  LL  GA+PN    +G+T +HA  +     LL  L+++GGDLRL ++ G  P    +    ++S  + DF Q+   +          +   +   +  +L H  + +     K +    +K +SP       FG    C++K+ +  G+++S+ +I +  +L       + +F CG    + + +W    V++K +     + N + +   +    +  I E      L HP++L LM V++  D      Q + +FER   GS+++ L+++  +F     C  + ++  V +AL ++H + +V  ++ SH + +V+    K+    F    E S     S L          YN       W APE+++ K       D+YSL  +I E YT  +P +    R + Q   T  +      +P+     LQ  ++  P  R   L D++Y +
Sbjct:   43 DVDCENNLGQTTLFCASLLGFTNVVELLLQYGANPNHRCVDGSTPVHAGVFSCKPWLLSGLLDAGGDLRLHDDQGRTPRDWAEAGAQEHSPMMLDFLQSCASHVWSLTQTHSTQDRQTTATSSKTLLHSPSLLELIRPKGSDPFVNKKLSPVCNAVPCFGFGKLCIDKSRQNVGVLASVPLIADC-ELVQAEDEALYSFTCGCLCCMTNYSWKGCRVTVKEL-----QTNATQKHAKLAGYHDLLITELEFCNQLFHPHLLQLMAVSITAD----LQQSRLVFERVHMGSLYDILYHRRAEFPMVKVCELLAVVLQVCEALLYLHGRALVLRALSSHSIIIVHPGVAKVTGLGFIVPSEGSCQGNMSPLPL----PAALYN-------WAAPEVIRGKKCT-RKADLYSLCTLIQELYTDAVPWRCVDPRWIKQTVDTGKALSPDSAVPQPYFHFLQSGLQPQPKDRTCSLQDLRYTL 498

[Close]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Match: ENSAMXT00000047880.1 (testis expressed 14, intercellular bridge forming factor [Source:NCBI gene;Acc:103034854])

HSP 1 Score: 82.8037 bits (203), Expect = 9.810e-16
Identity = 108/476 (22.69%), Postives = 198/476 (41.60%), Query Frame = 3

Query:  132 DINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNT--KNSEKIKDFEQNLFKNF---------KLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFG-NYFCLNKTIK--GLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQF---NNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLG--NFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP-KLCDIQYEI 1499
            D++ +N  G++ +F A+      +V  LL  GA+PN    +G+T +HA  +     LL  L+++GGDLRL ++ G  P    +    ++S  + DF Q+   +          +   +   +  +L H  + +     K +    +K +SP       FG    C++K+ +  G+++S+ +I +  +L       + +F CG                                    +TNQ            HP++L LM V++  D      Q + +FER   GS+++ L+++  +F     C  + ++  V +AL ++H + +V  ++ SH + +V+    K+    F    E S     S L          YN       W APE+++ K       D+YSL  +I E YT  +P +    R + Q   T  +      +P+     LQ  ++  P  R   L D++Y +
Sbjct:   43 DVDCENNLGQTTLFCASLLGFTNVVELLLQYGANPNHRCVDGSTPVHAGVFSCKPWLLSGLLDAGGDLRLHDDQGRTPRDWAEAGAQEHSPMMLDFLQSCASHVWSLTQTHSTQDRQTTATSSKTLLHSPSLLELIRPKGSDPFVNKKLSPVCNAVPCFGFGKLCIDKSRQNVGVLASVPLIADC-ELVQAEDEALYSFTCGCLC--------------------------------CMTNQLF----------HPHLLQLMAVSITAD----LQQSRLVFERVHMGSLYDILYHRRAEFPMVKVCELLAVVLQVCEALLYLHGRALVLRALSSHSIIIVHPGVAKVTGLGFIVPSEGSCQGNMSPLPL----PAALYN-------WAAPEVIRGKKCT-RKADLYSLCTLIQELYTDAVPWRCVDPRWIKQTVDTGKALSPDSAVPQPYFHFLQSGLQPQPKDRTCSLQDLRYTL 459

[Close]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Match: tnni3k (serine/threonine-protein kinase TNNI3K [Source:NCBI gene;Acc:103033588])

HSP 1 Score: 79.337 bits (194), Expect = 1.198e-14
Identity = 99/438 (22.60%), Postives = 181/438 (41.32%), Query Frame = 3

Query:  237 NIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKL-HLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNF-ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            N    +G+T LH+A +  ++RL+Q L+++G D+ LV  D  R         C M    K  + I      L K++K      P N  S P    S   + + L KI    + K  +     ++   + F L       +S ++   I+ S       K K  N                     KI+++   + N    +++  T+ F +E +IL  L HP V+  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F E+   +S D+    +  Q  N            +W+APE+           D++S A+ +WE  TG +P  +        ++   +  P    + + IP+ L  LL Q     P +RP+  ++
Sbjct:  334 NHQGRDGHTGLHSACFHGHIRLVQFLLDNGADMNLVACDPSRSSGEKEEQTCLMWAYEKGHDAIV----TLLKHYKRPQEDSPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--ADILLLRASLPSNFQLQ------LSELEFNEIIGSGSFGKVYKGKCRN---------------------KIVAIKRYRANTYCSKSD--TDMFCREVSILCRLNHPCVIQFVGACL--DDP---SQFAIVTQYVSGGSLFSLLHEQKRIIDLPSKLIIAIDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLLSMDE--DNMTKQPGN-----------LRWMAPEVFTQCTRYTVKADMFSYALCLWELLTGEVPFAHLKPAAAAADMAYHHIRP---PIGYSIPKPLSALLMQGWNASPEERPEFSEV 715

[Close]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Match: araf (A-Raf proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:103043654])

HSP 1 Score: 68.5514 bits (166), Expect = 2.046e-11
Identity = 43/206 (20.87%), Postives = 95/206 (46.12%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLK 1511
             +  I + C+  S++ +LH    +F+   RI++       +D++H++ I+H  + S+ ++L    + K+G+F  +   S           +W+          +  W+APE+++  D        D+Y   +V++E  +G +P+ N   R+ I     + Y +P   +L+   P+++ +L+   +K    +RP    I   I  ++
Sbjct:  378 HFAIITQWCEGSSLYRHLHVTETKFDTMRRIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGWTVKIGDFGLATVKS-----------RWSGSQQVEQPSGSILWMAPEVIRMQDPNPYTFQSDVYGYGVVLFELMSGTLPYSNINNRDQIIFMVGRGYLSPDLSKLTNNCPKSMKRLIIDCLKFKRDERPLFPQILVGIEQVQ 572

[Close]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040805-1])

HSP 1 Score: 68.5514 bits (166), Expect = 2.396e-11
Identity = 41/181 (22.65%), Postives = 89/181 (49.17%), Query Frame = 3

Query:  915 QYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLL 1436
            Q   + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+
Sbjct:  533 QLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGALPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLM 702

[Close]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040805-1])

HSP 1 Score: 64.6994 bits (156), Expect = 6.472e-11
Identity = 64/304 (21.05%), Postives = 128/304 (42.11%), Query Frame = 3

Query:  693 GLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            G +  V    WH   V++K++       NV+D     L   F  E  +L   RH              + L  M Y T      + + C+  S++ +LH    +F     I+I       +D++H++ I+H  + S+ ++L ++ + K+G+F           K+     +W+  +       +  W+APE+  +K++       D+Y+  IV++E  +  +P+ +   R+ I     + Y +P   ++    P+ + +L+   +K+    RP    I   I  L +S+ +     S+    RA
Sbjct:  485 GSFGTVYKGKWHGD-VAVKML-------NVTDPTPQQL-QAFKNEVGVLRKTRH-------------VNILLFMGYTTKPQLAIVTQWCEGSSLYRHLHILETKFEIFQLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHDDLTVKIGDF------GLATVKA-----RWSGSHQLEQPSGSILWMAPEVIRMKERNPYSFQSDVYAFGIVLFELMSCQLPYCSINNRDQIIFMVGRGYLSPDLSKVRSNCPKTMKRLMIDCLKKKREDRPLFPQILASIEQLARSLPKIHRSASEPSLNRA 755

[Close]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010455.1 (pep scaffold:Pmarinus_7.0:GL478446:2630:6356:1 gene:ENSPMAG00000009468.1 transcript:ENSPMAT00000010455.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 5.271e-9
Identity = 28/97 (28.87%), Postives = 53/97 (54.64%), Query Frame = 3

Query: 1230 KWLAPEILK-DKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKK 1514
            KW APE L    F  C   D++S  +++WE+++ G +P+   T +   ++    +  E   + P  + +L+ +  + +P QRP+  D+Q E+S+L K
Sbjct:   47 KWTAPEALNFGTFSTCS--DVWSFGVLLWETFSLGSMPYPGMTNQEAREQVERGYRLEAPEKCPREVHQLMLRCWQYEPKQRPRFSDLQRELSSLSK 141

[Close]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 6.792e-9
Identity = 42/191 (21.99%), Postives = 82/191 (42.93%), Query Frame = 3

Query:  918 YQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTT-PFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDI 1487
            Y  I E C  G ++  L    ++ +    +     +   + ++H   I+H  + S  V + +++  K+ +F  S E+   +K +++            +   T  W+APE+++++  V   +DI+S  +V+WE  TG IP+++     +I    +      +    PE    LL Q     P  RP    I
Sbjct:   75 YCIIMEYCAQGQLYEVL-RAGRRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSKEMR--EKSTRM------------SFAGTVAWMAPEVIRNE-PVSEKVDIWSFGVVLWELLTGEIPYRDVDSSAIIWGVGSNSLHLPIPASCPEGFKILLTQCWNSKPRNRPSFRQI 249

[Close]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007292.1 (pep scaffold:Pmarinus_7.0:GL476471:161062:207122:1 gene:ENSPMAG00000006520.1 transcript:ENSPMAT00000007292.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.7658 bits (138), Expect = 1.104e-8
Identity = 53/260 (20.38%), Postives = 115/260 (44.23%), Query Frame = 3

Query:  816 FIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRALSEILLKKE 1592
            F+ EA+I+G   HP+++ L GV       +   ++       +NGS+  +L   + QFN    + +L  +   + ++     +H  + +  V + ++   K+ +F  S  +  DD ++         Y  +       +W APE +  +     S D++S  +++WE  + G  P+ +   +++IQ     +        P  L +L+    +++ ++RP    I   ++ L K +     L +  +S+  LS  LL+++
Sbjct:  676 FLSEASIMGQFEHPSIIRLEGVVTKSKPVMIITEFM------ENGSLDAFLRGNDGQFNVGQLVGMLRGIAAGMKYLSDMNYIHRDLAARNVLVDSKLVCKVSDFGLSRGLE-DDPQA--------VYTTHGG-KIPIRWTAPEAIAFRKFTSAS-DVWSFGVLMWEVMSYGERPYWDMNNQDVIQAIEEGYRLPAPMDCPPALHQLMLDCWQKERTERPNFAQI---LAYLDKLLQNPASLHATSQSSVELSNPLLERK 915

[Close]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009834.1 (pep scaffold:Pmarinus_7.0:GL476739:7877:63472:1 gene:ENSPMAG00000008809.1 transcript:ENSPMAT00000009834.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 56.9954 bits (136), Expect = 1.639e-8
Identity = 49/221 (22.17%), Postives = 102/221 (46.15%), Query Frame = 3

Query:  816 FIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK-DKFVVCPSIDIYSLAIVIWESYT-GLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRP 1472
            F+ EA+I+G   HP+++ L GV       +   +Y       +NGS+ ++L  Q+ QF+    + +L  +   + ++     +H  + +  V + ++   K+ +F  S  +  DD ++         Y  + +     +W APE +   KF    + D++S  I++WE  + G  P+ N T +++IQ     +        P  L +L+    +++ ++RP
Sbjct:  640 FLSEASIMGQFEHPSIIRLEGVVTKTTPVMIITEYM------ENGSLDSFLRKQDGQFSVGQLVGMLRGIAAGVKYLSDMNYIHRDLAARNVLVDSKLVCKVSDFGLSRGLE-DDPQA--------VYTTHGS-KIPIRWTAPEAIAFHKFTT--ASDVWSFGILMWEVMSYGERPYWNMTNQDVIQSIEEGYRLPSPMDCPPALHQLMLDCWQKERTERP 842

[Close]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Match: GCN2 (Protein kinase; phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control [Source:SGD;Acc:S000002691])

HSP 1 Score: 55.0694 bits (131), Expect = 4.550e-8
Identity = 45/187 (24.06%), Postives = 89/187 (47.59%), Query Frame = 3

Query:  930 FERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEI--SFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIK----QDPSQRP 1472
             E C+N ++++ +H++N          +   +++AL +IHSQGI+H  +    +++    + K+G+F  +  +  S D  K   ++   +S N  + +  T  ++A E+L         ID+YSL I+ +E    + P      R  I +     S E      +N +K+ ++ I+     DP++RP
Sbjct:  788 MEYCENRTLYDLIHSENLNQQRDEYWRLFRQILEALSYIHSQGIIHRDLKPMNIFIDESRNVKIGDFGLAKNVHRSLDILKLDSQNLPGSSDNLTSAI-GTAMYVATEVLDGTGHYNEKIDMYSLGIIFFEM---IYPFSTGMERVNILKKLRSVSIEFPPDFDDNKMKVEKKIIRLLIDHDPNKRP 970

[Close]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Match: STE20 (Cdc42p-activated signal transducing kinase; involved in pheromone response, pseudohyphal/invasive growth, vacuole inheritance, down-regulation of sterol uptake; GBB motif binds Ste4p; member of the PAK (p21-activated kinase) family [Source:SGD;Acc:S000000999])

HSP 1 Score: 54.6842 bits (130), Expect = 5.520e-8
Identity = 42/145 (28.97%), Postives = 65/145 (44.83%), Query Frame = 3

Query: 1011 ILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNF-YNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQ 1442
            +    +  L+F+HS+G++H  I S  + L  E   KL +F    +I              N  N     +  T  W+APE++  K    P +DI+SL I+I E   G  P+ N+T   L   Y    +G    + PENL   L++
Sbjct:  719 VCRETLSGLEFLHSKGVLHRDIKSDNILLSMEGDIKLTDFGFCAQI--------------NELNLKRTTMVGTPYWMAPEVVSRKE-YGPKVDIWSLGIMIIEMIEGEPPYLNETP--LRALYLIATNGTPKLKEPENLSSSLKK 846

[Close]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144])

HSP 1 Score: 53.1434 bits (126), Expect = 1.932e-7
Identity = 36/140 (25.71%), Postives = 66/140 (47.14%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQ--NQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPH 1340
            I E C  GS+ + L     ++++       I+  ++ AL  IH   ++H  I +  V + NE + KL +F  + +++    ++ LR Q          +  T  W+APE++ +       +DI+SL I  +E  TG  P+
Sbjct:   98 IMEHCAGGSLRSLLRPGKIDEKYIGV----IMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVAAQVN----QTSLRRQ---------TMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPY 220

[Close]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Match: IPL1 (Aurora kinase of chromosomal passenger complex; mediates release of mono-oriented kinetochores from microtubules in meiosis I, and kinetochore release from SPB clusters at meiotic exit; helps maintain condensed chromosomes during anaphase; required for SPB cohesion and prevention of multipolar spindle formation; promotes telomerase release at G2/M; Iocalizes to nuclear foci that diffuse upon DNA replication stress; required for inhibition of karyopherin Pse1p upon SAC arrest [Source:SGD;Acc:S000006130])

HSP 1 Score: 50.8322 bits (120), Expect = 5.100e-7
Identity = 53/233 (22.75%), Postives = 101/233 (43.35%), Query Frame = 3

Query:  804 LTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLK----LLQQSIKQDPSQRPKLCDIQ 1490
            L  QF +E  I  SL HPN+    G           M+Y        NG M+  L   +  FN+    + +  + +ALD++H + I+H  I    + +   N  KL +F  S+    ++++                +  T  +L+PE+++ +     +ID ++L ++ +E  TG  P + +      +R        L  ++P N+ +    L+ + +K DP  R +L D++
Sbjct:  145 LQKQFRREVEIQTSLNHPNLTKSYGYFHDEKRVYLLMEYLV------NGEMYKLLR-LHGPFNDILASDYIYQIANALDYMHKKNIIHRDIKPENILIGFNNVIKLTDFGWSIINPPENRRK--------------TVCGTIDYLSPEMVESREYDH-TIDAWALGVLAFELLTGAPPFEEEMKDTTYKRIAA-----LDIKMPSNISQDAQDLILKLLKYDPKDRMRLGDVK 350

[Close]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072])

HSP 1 Score: 49.6766 bits (117), Expect = 2.181e-6
Identity = 37/146 (25.34%), Postives = 63/146 (43.15%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNL 1364
            + E C NGS+   +   +   +       +   +  L ++H +G++H  I +  + L  +N+ KL +F  S  ++     S L             L  T  W+APEIL ++     S DI+SL   + E  T   P+ N T  N+
Sbjct:   98 LLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVN----SSAL------------TLAGTLNWMAPEILGNRGASTLS-DIWSLGATVVEMLTKNPPYHNLTDANI 226

[Close]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Match: EDO37475 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFJ5])

HSP 1 Score: 63.929 bits (154), Expect = 5.698e-11
Identity = 47/204 (23.04%), Postives = 96/204 (47.06%), Query Frame = 3

Query:  927 IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSI--DIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTT-------PFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLK 1511
            + E     ++ + + + N++ +   ++ + + + +AL +IH+ GIVH  +    V + ++ S K+G+F    +   D   +  RS           L  TF + APE+L+ +    P+   D+YS AI +W+ +T  +P++ + ++ +I R          P   E+  R  E    L+  +    P+ RP + DI+   +N +
Sbjct:   96 LMEFVSTRTLQHVIDDTNEKMDFARKLRVNSEISNALVYIHNSGIVHLDLKPANVLIADDGSCKIGDF-GCCQFVDDQPNTPTRSY----------LTGTFAYRAPELLRGE---SPTFQADVYSFAICMWQIWTREVPYKLQNHQVVIFRVVACSLRPQIPTGNEIDNRYKE----LMTSAWAGKPTDRPTMGDIKETFANWR 281

[Close]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Match: EDO47089 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN75])

HSP 1 Score: 62.003 bits (149), Expect = 7.829e-10
Identity = 68/308 (22.08%), Postives = 131/308 (42.53%), Query Frame = 3

Query:  627 KIIVNSKDLTTDLKSKI---PNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILK--DKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSI 1520
            ++  NS D    L+ ++   P    G Y  V   NWH   V++K +       NV+D     L   F  E  +L   RH NVLL MG        + T       + C+  S++ +LH    +F   N I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +               +W+   +      +  W+A E+++  D        D+Y+  IV++E  +  +P+ +   ++ I     + Y  P   +    IP+   +L  + IK +  +RP    I   +  + +++
Sbjct:  419 RLRANSTDDWEILEGEVQMGPRIGSGSYGTVYKGNWHGA-VAIKTL-------NVTDPTPTQL-QAFKNEVAVLRKTRHVNVLLFMGCMSKPKLAIVT-------QWCEGSSLYRHLHVLENRFEVLNLIDIARQTAQGMDYLHAKKIIHRDLKSNNIFLQEDLTVKIGDFGLATI-----------KTRWSGSQYSEQPSGSILWMAAEVIRMLDPNPYSFHSDVYAFGIVLYELLSSSLPYAHVGNKDQILYMVGRGYLRPDMSKARNDIPKAFNRLCLECIKFNRDERPLFPQILASLEAIHRAL 699

[Close]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Match: EDO43690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RXV8])

HSP 1 Score: 55.4546 bits (132), Expect = 3.674e-8
Identity = 31/91 (34.07%), Postives = 52/91 (57.14%), Query Frame = 3

Query:  108 KSCLTTHSDINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMK 380
            K  L   +DIN QN  G + +  A     F++V  L+  GA  ++ ++EG T+LHAAA   ++ + + L+E+G D+  VNN+G  P  + +
Sbjct:   66 KKLLAKGADINYQNVDGLTALHQACIDENFDLVKVLVDKGASMDVRDNEGWTSLHAAASCGSVEIAKYLIENGADVAAVNNEGELPLDLAE 156

[Close]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Match: EDO48026 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKQ3])

HSP 1 Score: 55.0694 bits (131), Expect = 4.426e-8
Identity = 58/239 (24.27%), Postives = 104/239 (43.51%), Query Frame = 3

Query:  813 QFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQR-----YTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKK 1514
            Q  +E  +L  L HP  ++L       D   F + Y         G +  Y+         C +      +I AL+ +H   I+H  +    + L      K+ +F  +  ++ D++K++ R          N+   T ++++PE+L DK   C S DI++L  +I++  +GL P++      + Q+     Y+ P SG      PE    L++Q +  DP++R   C+     S LKK
Sbjct:   53 QVSREKEVLSRLNHPFFVILYFTFQDRDKLYFGLSY------AKKGELLPYITRLGSFDEKCTQF-YSAEIISALEHLHGLQIIHRDLKPENILLDENMHIKITDFGTAKILNKDEEKNKGR----------NSFVGTAQYVSPELLTDK-RACKSSDIWALGCIIYQLLSGLTPYRAGNEYQIFQKIIKNDYSFP-SG-----FPEIPKDLVEQLLILDPTKRLG-CEECGGFSELKK 266

[Close]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Match: EDO47771 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKZ8])

HSP 1 Score: 51.9878 bits (123), Expect = 8.321e-8
Identity = 37/167 (22.16%), Postives = 73/167 (43.71%), Query Frame = 3

Query:  948 GSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSI---DIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQ 1439
            G +H  LH   +  +    ++I ++V   L + H +G +H  + SH V +    + K+ NF  +  +   D   +  S          + +  ++W+APE L+ K    P+    D+YS  +++WE  T   P  N      +     P   ++S +  +N+  L++
Sbjct:    1 GFLHRLLHVDKEPLDEDTVLDIAHDVACGLLYTHQRGFIHCYLGSHSVVISESYNAKICNFNYAQAVKESDSSGEPIS----------HCEPLYEWMAPEQLRGK----PADKLGDVYSFGVMVWECVTRKRPFDNIANFKQVMGLVDPRMCKVSSKWSQNIRVLIK 153

[Close]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Match: tnni3k (serine/threonine-protein kinase TNNI3K [Source:NCBI gene;Acc:101167026])

HSP 1 Score: 87.0409 bits (214), Expect = 4.510e-17
Identity = 107/479 (22.34%), Postives = 201/479 (41.96%), Query Frame = 3

Query:  147 NRYGESLIFVAA-YFCEFEMVIHLLSIGA-DPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSI 1520
            N + E+ +  A  Y  + EMV  LL+  A   N    +G+TALH+A +  ++RL+Q L++SG D+ LV  D  R         C M    K  + I      L K++K     P N  S P    S   + + L KI    + K  +     ++   ++F L       +S ++   I+ S       + K  N                     KI+++   + N    ++++  + F +E +IL  L HP ++  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    L + IP+ +  LL +     P  RP+  ++   +S+L++ +
Sbjct:  324 NIFSETALHSACTYGKDLEMVKFLLNQNAMSINYQGRDGHTALHSACFHGHIRLVQFLLDSGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPDDSPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--AEVLVLRASLPSHFHLQ------LSELEFNEIIGSGSFGRVYRGKCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCRLNHPCIIQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRLIDLQSKLIIAIDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSVDEDNMTKQP------------GNLRWMAPEVFTQCTRYSVKADMFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PLGYSIPKPISALLMRGWNSCPEDRPEFSEV---VSSLEECL 744

[Close]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Match: tnni3k (serine/threonine-protein kinase TNNI3K [Source:NCBI gene;Acc:101167026])

HSP 1 Score: 86.2705 bits (212), Expect = 7.335e-17
Identity = 107/479 (22.34%), Postives = 201/479 (41.96%), Query Frame = 3

Query:  147 NRYGESLIFVAA-YFCEFEMVIHLLSIGA-DPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRP--------CQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNS---ILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKI--IVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIH--SQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQN----KTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSI 1520
            N + E+ +  A  Y  + EMV  LL+  A   N    +G+TALH+A +  ++RL+Q L++SG D+ LV  D  R         C M    K  + I      L K++K     P N  S P    S   + + L KI    + K  +     ++   ++F L       +S ++   I+ S       + K  N                     KI+++   + N    ++++  + F +E +IL  L HP ++  +G  L  DD     Q+  + +    GS+ + LH Q +  +  +++ I  +V   ++++H  +Q I+H  + SH + L  +    + +F  S  +   D+ +  +                 +W+APE+           D++S A+ +WE  TG IP  +        ++   +  P    L + IP+ +  LL +     P  RP+  ++   +S+L++ +
Sbjct:  302 NIFSETALHSACTYGKDLEMVKFLLNQNAMSINYQGRDGHTALHSACFHGHIRLVQFLLDSGADMNLVACDPSRSSGEKDEQTCLMWAYEKGHDAIV----TLLKHYKRPDDSPCNEYSQPGGDGSYVSVPSPLGKIKSMTKEK--AEVLVLRASLPSHFHLQ------LSELEFNEIIGSGSFGRVYRGKCRN---------------------KIVAIKRYRANTYCSKSDV--DMFCREVSILCRLNHPCIIQFVGACL--DDP---SQFAIVTQYISGGSLFSLLHEQKRLIDLQSKLIIAIDVAKGMEYLHNLTQPIIHRDLNSHNILLYEDGHAVVADFGESRFLQSVDEDNMTKQP------------GNLRWMAPEVFTQCTRYSVKADMFSYALCLWELLTGEIPFAHLKPAAAAADMAYHHIRP---PLGYSIPKPISALLMRGWNSCPEDRPEFSEV---VSSLEECL 722

[Close]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:101155814])

HSP 1 Score: 79.7221 bits (195), Expect = 7.288e-15
Identity = 69/304 (22.70%), Postives = 132/304 (43.42%), Query Frame = 3

Query:  693 GLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            G +  V    WH   V++K++       NV+D     L   F  E  +L   RH              + L  M Y T      + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  480 GSFGTVFKGKWHGD-VAVKML-------NVTDPTPQQL-QAFKNEVGVLRKTRH-------------VNILLFMGYTTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGSLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIHRSASEPSLNRA 750

[Close]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:101155814])

HSP 1 Score: 79.7221 bits (195), Expect = 7.652e-15
Identity = 69/304 (22.70%), Postives = 132/304 (43.42%), Query Frame = 3

Query:  693 GLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            G +  V    WH   V++K++       NV+D     L   F  E  +L   RH              + L  M Y T      + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  435 GSFGTVFKGKWHGD-VAVKML-------NVTDPTPQQL-QAFKNEVGVLRKTRH-------------VNILLFMGYTTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGSLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIHRSASEPSLNRA 705

[Close]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Match: braf (B-Raf proto-oncogene, serine/threonine kinase [Source:NCBI gene;Acc:101155814])

HSP 1 Score: 79.7221 bits (195), Expect = 7.824e-15
Identity = 69/304 (22.70%), Postives = 132/304 (43.42%), Query Frame = 3

Query:  693 GLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQT------IFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI--LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLI-----QRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRA 1565
            G +  V    WH   V++K++       NV+D     L   F  E  +L   RH              + L  M Y T      + + C+  S++++LH    +F     I+I       +D++H++ I+H  + S+ ++L  + + K+G+F  +   S           +W+  + +  L  +  W+APE+  L+DK       D+Y+  IV++E  +G +P+ N   R+ I     + Y +P   ++    P+ + +L+   +K+   +RP    I   I  L +S+ +     S+    RA
Sbjct:  480 GSFGTVFKGKWHGD-VAVKML-------NVTDPTPQQL-QAFKNEVGVLRKTRH-------------VNILLFMGYTTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS-----------RWSGSHQFEQLSGSILWMAPEVIRLQDKNPYSFQSDVYAFGIVLYELMSGSLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMADCLKKKREERPLFPQILASIELLARSLPKIHRSASEPSLNRA 750

[Close]

BLAST of Protein kinase, putative vs. Planmine SMEST
Match: SMESG000062960.1 (SMESG000062960.1)

HSP 1 Score: 1495.72 bits (3871), Expect = 0.000e+0
Identity = 807/808 (99.88%), Postives = 808/808 (100.00%), Query Frame = 3

Query:  132 DINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIXXXXXXXXXXXXXXXXXXXXXXERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFXXXXXXXXXXXXXXXXXXXXXTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 2555
            +INQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPNVLLLMGVNLVLDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC
Sbjct:   33 NINQQNRYGESLIFVAAYFCEFEMVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNNDGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSILNNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKDLTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTNILTNQFIKEANILGSLRHPNVLLLMGVNLVLDDKLFTMQYQTIFERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 840

HSP 2 Score: 57.7658 bits (138), Expect = 3.745e-8
Identity = 28/31 (90.32%), Postives = 30/31 (96.77%), Query Frame = 2

Query:    2 GDEFLQYLGYKKDSSNKNYLNFENKILSNNK 94
            GDEFLQYLGYKKDSSNKNYLNFENKIL+ N+
Sbjct:    6 GDEFLQYLGYKKDSSNKNYLNFENKILNINQ 36

[Close]

BLAST of Protein kinase, putative vs. Planmine SMEST
Match: SMESG000062960.1 (SMESG000062960.1)

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 348/348 (100.00%), Postives = 348/348 (100.00%), Query Frame = 3

Query: 1512 KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIXXXXXXXXXXXXXXXXXXXXXXERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFXXXXXXXXXXXXXXXXXXXXXTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 2555
            KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC
Sbjct:    7 KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 354

[Close]

Query: 1512 KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIXXXXXXXXXXXXXXXXXXXXXXERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFXXXXXXXXXXXXXXXXXXXXXTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 2555
            KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC
Sbjct:   32 KSINESLHLESDKESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNSFNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKYPSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGTNDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTNVKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNSPSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWSSTTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC 379

[Close]

BLAST of Protein kinase, putative vs. Planmine SMEST
Match: SMESG000053627.1 (SMESG000053627.1)

HSP 1 Score: 65.0846 bits (157), Expect = 1.641e-10
Identity = 48/185 (25.95%), Postives = 85/185 (45.95%), Query Frame = 3

Query:  933 ERCDNGSMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNF--ENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGELSFRIPENLLKLLQQSIKQDPSQRPKLC 1481
            E   NGS+ ++L + N + N        + +++ L+++HS+ I H  I +  V L ++N+ KL +F   N    + DD    ++             + T KW+APE+    +      DI+S  I + E  TG  P  +  Y+ +  R     +  L   + +NL  LL + ++ DP  RP +C
Sbjct:  550 EFMKNGSLKSFLEH-NGRLNETQIKHFSSQILEGLEYLHSKSICHRDIKAANVLLDDDNNAKLSDFGLANCFHEATDDLIRGIKQST----------NGTMKWMAPEVFTGNY--GSPADIWSFGITMIEMITGKDPFPDINYKEIYNRIKKYGNKSLKKEVSDNLFTLLDKCLQFDPKDRP-MC 720

[Close]

BLAST of Protein kinase, putative vs. Planmine SMEST
Match: SMESG000072548.1 (SMESG000072548.1)

HSP 1 Score: 60.8474 bits (146), Expect = 3.275e-9
Identity = 56/241 (23.24%), Postives = 111/241 (46.06%), Query Frame = 3

Query:  810 NQFIKEANILGSLRHPXXXXXXXXXXXXDDKLFTMQYQTIFERCDNGSMHNYLH-NQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLVNENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEILKDKFVVCPSIDIYSLAIVIWESYTGL-IPHQNKTYRNLIQRYTT------PFSGELSFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNL 1508
             +F++EA I+  LRH  ++ L+GV     D    M    I E    GS+  YL  ++ ++ N    I ++  + + + ++ S+ +VH  + +  + + ++ + K+ +F    EI+    ++Q +           NL   +KW APE  K K     S D++S  IV++E  T    P+ +   + +I + ++      P +       P+ + K++      DP+QRP    +Q ++  L
Sbjct:  256 EKFLQEAKIMHKLRHRKIVELLGVCTEPQD----MPMIIIVEFMKFGSLKEYLKSDEGKKTNLSQMIHMMAEISEGMAYLESEKVVHRDLRADNILVADDLTVKVADF-GLTEITEGANENQEK----------KNLRFPYKWTAPEAAKSKVFTSKS-DVWSFGIVMYEILTWSNPPYPDTPAKEVIDKVSSGYRMPNPETFIPGVHCPDEIYKIMIDCWHADPAQRPTFASLQEQLDTL 480

The following BLAST results are available for this feature:

BLAST of Protein kinase, putative vs. Ensembl Human
BLAST of Protein kinase, putative vs. Ensembl Celegans
BLAST of Protein kinase, putative vs. Ensembl Fly
BLAST of Protein kinase, putative vs. Ensembl Zebrafish
BLAST of Protein kinase, putative vs. Ensembl Xenopus
BLAST of Protein kinase, putative vs. Ensembl Mouse
BLAST of Protein kinase, putative vs. UniProt/SwissProt
BLAST of Protein kinase, putative vs. TrEMBL
BLAST of Protein kinase, putative vs. Ensembl Cavefish
BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
BLAST of Protein kinase, putative vs. Ensembl Yeast
BLAST of Protein kinase, putative vs. Ensembl Nematostella
BLAST of Protein kinase, putative vs. Ensembl Medaka
BLAST of Protein kinase, putative vs. Planmine SMEST

BLAST of Protein kinase, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TEX14	2.154e-25	25.71	testis expressed 14, intercellular bridge forming ...	[more]
TEX14	2.259e-25	25.71	testis expressed 14, intercellular bridge forming ...	[more]
TEX14	2.104e-23	25.35	testis expressed 14, intercellular bridge forming ...	[more]
TNNI3K	2.591e-15	22.27	TNNI3 interacting kinase [Source:HGNC Symbol;Acc:H...	[more]
FPGT-TNNI3K	2.903e-15	22.27	FPGT-TNNI3K readthrough [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of Protein kinase, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
F59A3.8	1.264e-11	24.19	Tyrosine-protein kinase [Source:UniProtKB/TrEMBL;...	[more]
vab-1	1.555e-9	24.00	Ephrin receptor 1 [Source:UniProtKB/Swiss-Prot;Ac...	[more]
lin-45	1.987e-9	24.00	Raf homolog serine/threonine-protein kinase [Sour...	[more]
lin-45	2.005e-9	24.00	Raf homolog serine/threonine-protein kinase [Sour...	[more]
lin-45	2.072e-9	24.00	Raf homolog serine/threonine-protein kinase [Sour...	[more]

BLAST of Protein kinase, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Raf	3.828e-9	20.90	gene:FBgn0003079 transcript:FBtr0070401	[more]
Raf	3.828e-9	20.90	gene:FBgn0003079 transcript:FBtr0344007	[more]
Eph	4.514e-9	22.40	gene:FBgn0025936 transcript:FBtr0301285	[more]
Eph	4.571e-9	22.40	gene:FBgn0025936 transcript:FBtr0089083	[more]
Eph	4.614e-9	22.40	gene:FBgn0025936 transcript:FBtr0089082	[more]

BLAST of Protein kinase, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
braf	4.104e-14	22.77	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
braf	4.141e-14	22.77	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
tnni3k	4.572e-14	21.96	TNNI3 interacting kinase [Source:ZFIN;Acc:ZDB-GENE...	[more]
raf1a	7.867e-12	23.53	Raf-1 proto-oncogene, serine/threonine kinase a [S...	[more]
raf1a	8.757e-12	23.53	Raf-1 proto-oncogene, serine/threonine kinase a [S...	[more]

BLAST of Protein kinase, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MGC115642	8.125e-19	22.98	hypothetical protein MGC115642 [Source:Xenbase;Acc...	[more]
tnni3k	5.770e-14	21.87	TNNI3 interacting kinase [Source:NCBI gene;Acc:100...	[more]
tnni3k	7.230e-14	21.87	TNNI3 interacting kinase [Source:NCBI gene;Acc:100...	[more]
tnni3k	9.714e-14	21.87	TNNI3 interacting kinase [Source:NCBI gene;Acc:100...	[more]
BRAF	1.508e-13	22.32	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]

BLAST of Protein kinase, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Tex14	8.606e-27	27.45	testis expressed gene 14 [Source:MGI Symbol;Acc:MG...	[more]
Tnni3k	1.211e-14	20.74	TNNI3 interacting kinase [Source:MGI Symbol;Acc:MG...	[more]
Braf	1.800e-14	22.77	Braf transforming gene [Source:MGI Symbol;Acc:MGI:...	[more]
Braf	1.942e-14	22.77	Braf transforming gene [Source:MGI Symbol;Acc:MGI:...	[more]
Tnni3k	1.325e-12	23.02	TNNI3 interacting kinase [Source:MGI Symbol;Acc:MG...	[more]

BLAST of Protein kinase, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|F1MJR8\|TEX14_BOVIN	1.499e-26	25.89	Inactive serine/threonine-protein kinase TEX14 OS=...	[more]
sp\|Q7M6U3\|TEX14_MOUSE	6.020e-26	27.45	Inactive serine/threonine-protein kinase TEX14 OS=...	[more]
sp\|F1M5M3\|TEX14_RAT	1.909e-25	26.49	Inactive serine/threonine-protein kinase TEX14 OS=...	[more]
sp\|Q8IWB6\|TEX14_HUMAN	1.010e-22	25.35	Inactive serine/threonine-protein kinase TEX14 OS=...	[more]
sp\|Q59H18\|TNI3K_HUMAN	1.244e-14	22.27	Serine/threonine-protein kinase TNNI3K OS=Homo sap...	[more]

BLAST of Protein kinase, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267ECB1	1.176e-48	28.11	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A267H0D6	2.982e-45	28.11	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A226F6S1	5.930e-32	27.58	Inactive serine/threonine-protein kinase TEX14 OS=...	[more]
A0A4V3SFS2	1.836e-29	28.69	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A4S2LZV7	2.054e-29	28.69	Uncharacterized protein OS=Opisthorchis felineus O...	[more]

BLAST of Protein kinase, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000008987.2	9.883e-21	23.43	testis expressed 14, intercellular bridge forming ...	[more]
ENSAMXT00000047880.1	9.810e-16	22.69	testis expressed 14, intercellular bridge forming ...	[more]
tnni3k	1.198e-14	22.60	serine/threonine-protein kinase TNNI3K [Source:NCB...	[more]
araf	2.046e-11	20.87	A-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
braf	2.396e-11	22.65	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]

BLAST of Protein kinase, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
braf	6.472e-11	21.05	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
ENSPMAT00000010455.1	5.271e-9	28.87	pep scaffold:Pmarinus_7.0:GL478446:2630:6356:1 gen...	[more]
ENSPMAT00000008193.1	6.792e-9	21.99	pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-...	[more]
ENSPMAT00000007292.1	1.104e-8	20.38	pep scaffold:Pmarinus_7.0:GL476471:161062:207122:1...	[more]
ENSPMAT00000009834.1	1.639e-8	22.17	pep scaffold:Pmarinus_7.0:GL476739:7877:63472:1 ge...	[more]

BLAST of Protein kinase, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
GCN2	4.550e-8	24.06	Protein kinase; phosphorylates the alpha-subunit o...	[more]
STE20	5.520e-8	28.97	Cdc42p-activated signal transducing kinase; involv...	[more]
KIC1	1.932e-7	25.71	Protein kinase of the PAK/Ste20 family, required f...	[more]
IPL1	5.100e-7	22.75	Aurora kinase of chromosomal passenger complex; me...	[more]
CDC15	2.181e-6	25.34	Protein kinase of the Mitotic Exit Network; locali...	[more]

BLAST of Protein kinase, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO37475	5.698e-11	23.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47089	7.829e-10	22.08	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO43690	3.674e-8	34.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48026	4.426e-8	24.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47771	8.321e-8	22.16	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein kinase, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tnni3k	4.510e-17	22.34	serine/threonine-protein kinase TNNI3K [Source:NCB...	[more]
tnni3k	7.335e-17	22.34	serine/threonine-protein kinase TNNI3K [Source:NCB...	[more]
braf	7.288e-15	22.70	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
braf	7.652e-15	22.70	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]
braf	7.824e-15	22.70	B-Raf proto-oncogene, serine/threonine kinase [Sou...	[more]

BLAST of Protein kinase, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000062960.1	3.745e-8	99.88	SMESG000062960.1	[more]
SMESG000062960.1	0.000e+0	100.00	SMESG000062960.1	[more]
SMESG000062960.1	0.000e+0	100.00	SMESG000062960.1	[more]
SMESG000053627.1	1.641e-10	25.95	SMESG000053627.1	[more]
SMESG000072548.1	3.275e-9	23.24	SMESG000072548.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025494 ID=SMED30025494|Name=Protein kinase, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=2646bp
AGGCGATGAATTTTTGCAATATTTAGGTTACAAAAAAGACAGTTCAAATA
AAAATTATTTGAATTTTGAAAATAAAATTTTAAGTAATAACAAAATTACT
CCATTAAAAGTCTTGTTTAACTACCCATTCAGACATCAACCAGCAAAATA
GATATGGAGAATCGCTGATATTTGTGGCAGCTTATTTTTGCGAATTTGAA
ATGGTCATCCATTTATTAAGCATTGGCGCAGACCCGAATATAGCAAACCA
CGAAGGCAACACAGCTCTCCACGCGGCTGCTTACTTTGACAATTTGCGGC
TGTTGCAGATTCTTGTGGAAAGTGGCGGAGATTTGCGATTGGTCAATAAT
GATGGGCTGAGGCCCTGTCAAATGATGAAAAACACAAAAAACTCTGAGAA
AATCAAAGATTTCGAACAGAACCTGTTTAAAAATTTTAAGCTTCATCTAT
CCATTCCGAACAATCCGATTTCTTTACCACATCGGAAAAATTCTATTTTG
AATAATCTACAGAAAATTAACCGAAACAACCAGCATAAAATCGTTTCACC
ATATTTTACCTTTCAAAGCGGCTTTGGAAACTATTTTTGTCTCAACAAAA
CAATCAAAGGTCTTATTTCTTCAATTAAAATCATCGTTAATTCCAAAGAC
TTAACCACCGATCTCAAATCTAAGATTCCAAATTTTCCATGTGGACTCTA
TACAAAGGTTATCAGCAAAAATTGGCATTCTACTCCCGTGTCATTGAAAA
TTATCAGTTTATTAGATGGTAAAGAAAATGTATCGGATAGAAGAACGAAT
ATTCTAACAAATCAGTTTATCAAGGAAGCCAATATTCTGGGATCCCTGCG
CCACCCAAATGTCCTACTGCTCATGGGCGTAAACCTGGTTTTGGATGACA
AATTATTCACAATGCAATACCAAACTATATTTGAAAGATGTGACAACGGT
TCCATGCATAACTATTTGCACAATCAAAATCAACAATTCAACAATTGCAA
CAGAATAGAAATACTGAATAATGTTATAGATGCTTTGGATTTTATTCATA
GCCAAGGAATCGTGCATGGAAGTATTTGTTCCCACTGTGTCTATCTTGTG
AATGAGAATTCAGGGAAATTAGGAAACTTTGAAAACTCGATGGAAATCAG
CTTCGATGATAAAAAATCACAACTGAGATCTCAACAATGGAATTCTTACA
ATTTTTACAATAATCTTGACAACACTTTCAAATGGCTTGCACCAGAAATT
TTGAAAGACAAATTCGTTGTTTGCCCTTCAATTGATATTTACAGTCTAGC
AATTGTAATATGGGAGAGCTATACCGGCCTTATTCCGCATCAGAATAAAA
CATACCGGAACTTAATCCAGAGATATACAACACCATTTTCTGGGGAATTA
TCATTTCGTATTCCCGAAAACCTTCTAAAATTACTCCAACAATCCATTAA
ACAAGATCCCTCTCAAAGGCCAAAGTTGTGTGATATTCAATATGAAATTT
CCAATTTAAAAAAATCAATAAATGAAAGTCTTCATCTTGAAAGTGATAAA
GAATCGACAAGAGCTTTATCAGAAATTCTGTTAAAAAAGGAAAAAATAGA
CGATTTTCAACCACCAATAGAAGTTCATGTGGAAACCACAGATGATGATA
CTTATGCGTCGATTTCCTCCAATAGAACCTCTGTGAAAAAATCTAATTCT
TTTAACTGCAGCAGAGAAAATAAAACCTCCCAAACTACAGGTTCGCAATT
CCTTAAACATGTCACTGATAGTGCATGGAGGAAGAAATTAGAATATCGAG
ATCTAGCAGCTTTGCCGAATTTCCAAAACTCAGAAATCAACTGGAAATAC
CCCTCAACTCAAACTGAAATTGTCATCGAAGGCCAAGGAAATCTATCCAA
CTCCATGCATAAAGTCTCTATTACTAGAGGAATGAAACCGGCTAGCCATC
AAATCAGTTTATCGGCAAGCCAAACTAATATTTGCACGATTCTTGGAACG
AACGATTTGATTAAATCTAGCAGTCGAGGGAGTTTACACAATAATTCCTC
ATCTCACAGTTTAAATAAGTCCAGCAATGAAAGAAAAGTCACAAACAAAC
CAAATCCGTTTTCATCATACAAACAATTCAATTGTGGAACATTCACAAAT
GTAAAACATTCCAGACCGAACATTAAATCCAACATTGCCAGCCTCATTGA
GAAATATGAAAATTCAGAACTCCATCCGTATAGCGGCGGCGCATCAAATA
ACTCGACTCCCATTGCGGCCGTTTCTCGAAATTTATCCAATTATAATTCT
CCGTCGAAAGTCATTTTTAACAGTTCAAATTCATCAGCAGATTCACCAAA
AAGTAGTGCAGCGTCGCCCTCGTCAGCGTCAACGACGACATATGGTAAAA
AATCATCATATTTCCCTTCTTTTATTAAACGAGAAACGAGCAAATGGTCT
TCAACGACCGAAGATGAGGAAAATAACAAATTCAATCGTAATTTTAATAC
GAAATCCCGACATCAAAAACAAAAGTTATTTGGTGATATAACTAATAACT
TGTGTTAGGATTTTTAAATAATGAGGATTTTATGTATATTTTTCGATTAT
TATTAATAATATTTCAATGTCATTGTTAAGTGTAATGTTAATGTCA

protein sequence of SMED30025494-orf-1

>SMED30025494-orf-1 ID=SMED30025494-orf-1|Name=SMED30025494-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=786bp
MVIHLLSIGADPNIANHEGNTALHAAAYFDNLRLLQILVESGGDLRLVNN
DGLRPCQMMKNTKNSEKIKDFEQNLFKNFKLHLSIPNNPISLPHRKNSIL
NNLQKINRNNQHKIVSPYFTFQSGFGNYFCLNKTIKGLISSIKIIVNSKD
LTTDLKSKIPNFPCGLYTKVISKNWHSTPVSLKIISLLDGKENVSDRRTN
ILTNQFIKEANILGSLRHPNVLLLMGVNLVLDDKLFTMQYQTIFERCDNG
SMHNYLHNQNQQFNNCNRIEILNNVIDALDFIHSQGIVHGSICSHCVYLV
NENSGKLGNFENSMEISFDDKKSQLRSQQWNSYNFYNNLDNTFKWLAPEI
LKDKFVVCPSIDIYSLAIVIWESYTGLIPHQNKTYRNLIQRYTTPFSGEL
SFRIPENLLKLLQQSIKQDPSQRPKLCDIQYEISNLKKSINESLHLESDK
ESTRALSEILLKKEKIDDFQPPIEVHVETTDDDTYASISSNRTSVKKSNS
FNCSRENKTSQTTGSQFLKHVTDSAWRKKLEYRDLAALPNFQNSEINWKY
PSTQTEIVIEGQGNLSNSMHKVSITRGMKPASHQISLSASQTNICTILGT
NDLIKSSSRGSLHNNSSSHSLNKSSNERKVTNKPNPFSSYKQFNCGTFTN
VKHSRPNIKSNIASLIEKYENSELHPYSGGASNNSTPIAAVSRNLSNYNS
PSKVIFNSSNSSADSPKSSAASPSSASTTTYGKKSSYFPSFIKRETSKWS
STTEDEENNKFNRNFNTKSRHQKQKLFGDITNNLC*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0000165	MAPK cascade
GO:0000186	activation of MAPKK activity
GO:0007140	male meiotic nuclear division
GO:0007094	mitotic spindle assembly checkpoint
GO:0008608	attachment of spindle microtubules to kinetochore
GO:0043063	intercellular bridge organization
GO:0051306	mitotic sister chromatid separation
GO:0006468	protein phosphorylation
GO:0016310	phosphorylation

Vocabulary: **molecular function**
Term	Definition
GO:0004709	MAP kinase kinase kinase activity
GO:0016740	transferase activity
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0005524	ATP binding
GO:0016301	kinase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036770	Ankyrin_rpt-contain_sf
IPR039339	Tex14
IPR002110	Ankyrin_rpt
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR020683	Ankyrin_rpt-contain_dom
IPR000719	Prot_kinase_dom
IPR011009	Kinase-like_dom_sf

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002110	Ankyrin repeat	SMART	SM00248	ANK_2a	coord: 18..47 e-value: 0.0022 score: 27.3
IPR002110	Ankyrin repeat	PROSITE	PS50088	ANK_REPEAT	coord: 18..50 score: 12.476
None	No IPR available	PFAM	PF13857	Ank_5	coord: 5..57 e-value: 1.7E-6 score: 28.2
None	No IPR available	GENE3D	G3DSA:1.10.510.10		coord: 247..464 e-value: 1.9E-30 score: 107.7
None	No IPR available	GENE3D	G3DSA:3.30.200.20		coord: 154..241 e-value: 2.8E-7 score: 32.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 608..636
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 748..764
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 747..771
None	No IPR available	PANTHER	PTHR23060:SF1	INACTIVE SERINE/THREONINE-PROTEIN KINASE TEX14	coord: 2..633
IPR036770	Ankyrin repeat-containing domain superfamily	GENE3D	G3DSA:1.25.40.20		coord: 1..81 e-value: 1.3E-13 score: 52.7
IPR036770	Ankyrin repeat-containing domain superfamily	SUPERFAMILY	SSF48403	Ankyrin repeat	coord: 2..71
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 199..430 e-value: 6.0E-26 score: 91.3
IPR039339	Inactive serine/threonine-protein kinase TEX14	PANTHER	PTHR23060	TESTIS EXPRESSED GENE 14	coord: 2..633
IPR020683	Ankyrin repeat-containing domain	PROSITE	PS50297	ANK_REP_REGION	coord: 1..55 score: 17.767
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 156..444 score: 23.962
IPR011009	Protein kinase-like domain superfamily	SUPERFAMILY	SSF56112	Protein kinase-like (PK-like)	coord: 176..441