Histone H4

Overview


Name	Histone H4
Smed ID	SMED30025482
Length (bp)	552

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Histone H4 (SMED30025482) t-SNE clustered cells

Violin plots show distribution of expression levels for Histone H4 (SMED30025482) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Histone H4 (SMED30025482) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Histone H4 (SMED30025482) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025482

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X2 cell	SMED30025482	SMESG000054351.1	SmedASXL_012973	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
epidermis	SMED30025482	SMESG000054351.1	dd_Smed_v4_5700_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30025482	SMESG000054351.1	dd_Smed_v4_5700_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30025482	SMESG000054351.1	dd_Smed_v4_5700_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Histone H4 vs. Ensembl Human
Match: H4C9 (H4 clustered histone 9 [Source:HGNC Symbol;Acc:HGNC:4793])

HSP 1 Score: 163.31 bits (412), Expect = 6.308e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Human
Match: H4C15 (H4 clustered histone 15 [Source:HGNC Symbol;Acc:HGNC:29607])

HSP 1 Score: 163.31 bits (412), Expect = 6.308e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Human
Match: H4C14 (H4 clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4794])

HSP 1 Score: 163.31 bits (412), Expect = 6.308e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Celegans
Match: his-67 (Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P62784])

HSP 1 Score: 161.77 bits (408), Expect = 8.940e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Celegans
Match: his-64 (Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P62784])

HSP 1 Score: 161.77 bits (408), Expect = 8.940e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Celegans
Match: his-60 (Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P62784])

HSP 1 Score: 161.77 bits (408), Expect = 8.940e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Celegans
Match: his-56 (Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P62784])

HSP 1 Score: 161.77 bits (408), Expect = 8.940e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Celegans
Match: his-50 (Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P62784])

HSP 1 Score: 161.77 bits (408), Expect = 8.940e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Fly
Match: His4:CG33899 (gene:FBgn0053899 transcript:FBtr0091903)

HSP 1 Score: 162.925 bits (411), Expect = 3.484e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Fly
Match: His4:CG33897 (gene:FBgn0053897 transcript:FBtr0091901)

HSP 1 Score: 162.925 bits (411), Expect = 3.484e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Fly
Match: His4r (gene:FBgn0013981 transcript:FBtr0334029)

HSP 1 Score: 162.925 bits (411), Expect = 3.484e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Fly
Match: His4r (gene:FBgn0013981 transcript:FBtr0082962)

HSP 1 Score: 162.925 bits (411), Expect = 3.484e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Fly
Match: His4r (gene:FBgn0013981 transcript:FBtr0082963)

HSP 1 Score: 162.925 bits (411), Expect = 3.484e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Zebrafish
Match: hist1h4l (histone 1, H4, like [Source:ZFIN;Acc:ZDB-GENE-070927-10])

HSP 1 Score: 163.31 bits (412), Expect = 4.013e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Zebrafish
Match: zgc:153409 (zgc:153409 [Source:ZFIN;Acc:ZDB-GENE-060929-224])

HSP 1 Score: 163.31 bits (412), Expect = 4.013e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Xenopus
Match: zbtb22 (zinc finger and BTB domain containing 22 [Source:Xenbase;Acc:XB-GENE-6458515])

HSP 1 Score: 163.31 bits (412), Expect = 5.718e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Xenopus
Match: hist1h4c (histone H4 [Source:NCBI gene;Acc:101732638])

HSP 1 Score: 163.31 bits (412), Expect = 5.718e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Xenopus
Match: hist1h4c (H4 clustered histone 1 [Source:NCBI gene;Acc:549623])

HSP 1 Score: 163.31 bits (412), Expect = 5.718e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Xenopus
Match: cpa1 (carboxypeptidase A1 [Source:Xenbase;Acc:XB-GENE-960032])

HSP 1 Score: 163.31 bits (412), Expect = 5.718e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Mouse
Match: H4c14 (H4 clustered histone 14 [Source:MGI Symbol;Acc:MGI:2140113])

HSP 1 Score: 163.31 bits (412), Expect = 4.331e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Mouse
Match: H4c9 (H4 clustered histone 9 [Source:MGI Symbol;Acc:MGI:2448432])

HSP 1 Score: 163.31 bits (412), Expect = 4.331e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Mouse
Match: Hist1h4n (histone cluster 1, H4n [Source:MGI Symbol;Acc:MGI:4843992])

HSP 1 Score: 163.31 bits (412), Expect = 4.331e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Mouse
Match: Hist1h4m (histone cluster 1, H4m [Source:MGI Symbol;Acc:MGI:2448441])

HSP 1 Score: 163.31 bits (412), Expect = 4.331e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Mouse
Match: H4c12 (H4 clustered histone 12 [Source:MGI Symbol;Acc:MGI:2448439])

HSP 1 Score: 163.31 bits (412), Expect = 4.331e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. UniProt/SwissProt
Match: sp|Q6WV74|H4_MYTCH (Histone H4 OS=Mytilus chilensis OX=173667 PE=3 SV=3)

HSP 1 Score: 163.31 bits (412), Expect = 2.900e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. UniProt/SwissProt
Match: sp|Q28DR4|H4_XENTR (Histone H4 OS=Xenopus tropicalis OX=8364 GN=TGas006m08.1 PE=3 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 3.029e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. UniProt/SwissProt
Match: sp|P62799|H4_XENLA (Histone H4 OS=Xenopus laevis OX=8355 PE=1 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 3.029e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. UniProt/SwissProt
Match: sp|P62798|H4_XENBO (Histone H4 OS=Xenopus borealis OX=8354 PE=3 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 3.029e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. UniProt/SwissProt
Match: sp|P62794|H4_URECA (Histone H4 OS=Urechis caupo OX=6431 PE=3 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 3.029e-51
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. TrEMBL
Match: E0VXR4 (Histone H4 OS=Pediculus humanus subsp. corporis OX=121224 GN=8231603 PE=3 SV=1)

HSP 1 Score: 167.933 bits (424), Expect = 1.920e-50
Identity = 88/99 (88.89%), Postives = 90/99 (90.91%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPQMLIVVNCSNIVILSS 438
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGP+   V     + ILSS
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPKYSHV-----MFILSS 115

[Close]

BLAST of Histone H4 vs. TrEMBL
Match: A0A0D2MND9 (Histone H4 OS=Gossypium raimondii OX=29730 GN=B456_003G134900 PE=3 SV=1)

HSP 1 Score: 167.548 bits (423), Expect = 2.076e-50
Identity = 82/93 (88.17%), Postives = 88/93 (94.62%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPQMLIVVNCSN 420
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLK+FLENVIRDAVTYTEHA+RKTVTAMDVVYALKRQGRTLYGFGG Q  +++  S+
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGGFQSTMLLRASH 114

[Close]

BLAST of Histone H4 vs. TrEMBL
Match: A0A3S3SL30 (Histone H4 OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_06414 PE=3 SV=1)

HSP 1 Score: 167.162 bits (422), Expect = 2.787e-50
Identity = 83/86 (96.51%), Postives = 85/86 (98.84%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPQML 399
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGP ++
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPPLV 107

[Close]

BLAST of Histone H4 vs. TrEMBL
Match: A0A3Q2DQK7 (Histone H4 OS=Cyprinodon variegatus OX=28743 PE=3 SV=1)

HSP 1 Score: 168.318 bits (425), Expect = 6.048e-50
Identity = 89/118 (75.42%), Postives = 95/118 (80.51%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPQMLIVVNCSNIVILSSNSQQFY*RYLEINFTIANF 495
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG  +    V   NI    SN  Q   + L +  ++ +F
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGESKRFFFVKIFNI----SNCIQVILQILTVCCSLGSF 135

[Close]

BLAST of Histone H4 vs. TrEMBL
Match: A0A1S3GPA9 (Histone H4 OS=Dipodomys ordii OX=10020 GN=LOC106000013 PE=3 SV=1)

HSP 1 Score: 166.007 bits (419), Expect = 6.528e-50
Identity = 83/87 (95.40%), Postives = 84/87 (96.55%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGPQMLI 402
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG +  I
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGGKKSFI 108

[Close]

BLAST of Histone H4 vs. Ensembl Cavefish
Match: ENSAMXT00000036719.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002305.1:21807:22190:1 gene:ENSAMXG00000036201.1 transcript:ENSAMXT00000036719.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 163.31 bits (412), Expect = 1.923e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   12 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 93

[Close]

BLAST of Histone H4 vs. Ensembl Cavefish
Match: ENSAMXT00000032266.1 (pep primary_assembly:Astyanax_mexicanus-2.0:21:10098617:10101488:1 gene:ENSAMXG00000042821.1 transcript:ENSAMXT00000032266.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 163.31 bits (412), Expect = 2.446e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   12 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 93

[Close]

BLAST of Histone H4 vs. Ensembl Cavefish
Match: ENSAMXT00000025592.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002305.1:172325:175033:-1 gene:ENSAMXG00000024866.2 transcript:ENSAMXT00000025592.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 163.31 bits (412), Expect = 3.060e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   20 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 101

[Close]

BLAST of Histone H4 vs. Ensembl Cavefish
Match: ENSAMXT00000025764.2 (histone H4 [Source:NCBI gene;Acc:111190747])

HSP 1 Score: 163.31 bits (412), Expect = 3.401e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Cavefish
Match: ENSAMXT00000043832.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002305.1:155578:160764:1 gene:ENSAMXG00000039753.1 transcript:ENSAMXT00000043832.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.155 bits (409), Expect = 8.727e-52
Identity = 81/82 (98.78%), Postives = 81/82 (98.78%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEET GVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   27 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETHGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 108

[Close]

BLAST of Histone H4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002372.1 (pep scaffold:Pmarinus_7.0:GL476925:46740:47638:1 gene:ENSPMAG00000002161.1 transcript:ENSPMAT00000002372.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 4.333e-38
Identity = 65/81 (80.25%), Postives = 68/81 (83.95%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 384
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKT+  +DV     RQ   L+   
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTLVLIDVA----RQNANLHPLN 98

[Close]

BLAST of Histone H4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002391.1 (pep scaffold:Pmarinus_7.0:GL476925:199603:200503:1 gene:ENSPMAG00000002178.1 transcript:ENSPMAT00000002391.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 4.333e-38
Identity = 65/81 (80.25%), Postives = 68/81 (83.95%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 384
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKT+  +DV     RQ   L+   
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTLVLIDVA----RQNANLHPLN 98

[Close]

BLAST of Histone H4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002392.1 (pep scaffold:Pmarinus_7.0:GL476925:215484:216380:1 gene:ENSPMAG00000002179.1 transcript:ENSPMAT00000002392.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 4.333e-38
Identity = 65/81 (80.25%), Postives = 68/81 (83.95%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 384
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKT+  +DV     RQ   L+   
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTLVLIDVA----RQNANLHPLN 98

[Close]

BLAST of Histone H4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002394.1 (pep scaffold:Pmarinus_7.0:GL476925:225178:226079:1 gene:ENSPMAG00000002180.1 transcript:ENSPMAT00000002394.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 125.561 bits (314), Expect = 4.333e-38
Identity = 65/81 (80.25%), Postives = 68/81 (83.95%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG 384
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKT+  +DV     RQ   L+   
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTLVLIDVA----RQNANLHPLN 98

[Close]

BLAST of Histone H4 vs. Ensembl Yeast
Match: HHF2 (Histone H4; core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF1); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity [Source:SGD;Acc:S000004975])

HSP 1 Score: 152.525 bits (384), Expect = 7.550e-49
Identity = 74/82 (90.24%), Postives = 79/82 (96.34%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEE R VLK FLE+VIRD+VTYTEHAKRKTVT++DVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Yeast
Match: HHF1 (Histone H4; core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF2); contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity [Source:SGD;Acc:S000000213])

HSP 1 Score: 152.525 bits (384), Expect = 7.550e-49
Identity = 74/82 (90.24%), Postives = 79/82 (96.34%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEE R VLK FLE+VIRD+VTYTEHAKRKTVT++DVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Nematostella
Match: EDO40764 (Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0])

HSP 1 Score: 162.54 bits (410), Expect = 1.861e-52
Identity = 81/82 (98.78%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Nematostella
Match: EDO27765 (Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0])

HSP 1 Score: 162.54 bits (410), Expect = 1.861e-52
Identity = 81/82 (98.78%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Nematostella
Match: EDO38246 (Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0])

HSP 1 Score: 162.54 bits (410), Expect = 1.861e-52
Identity = 81/82 (98.78%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Nematostella
Match: EDO30153 (Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0])

HSP 1 Score: 162.54 bits (410), Expect = 1.861e-52
Identity = 81/82 (98.78%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Nematostella
Match: EDO46460 (Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0])

HSP 1 Score: 162.54 bits (410), Expect = 1.861e-52
Identity = 81/82 (98.78%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            +LRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 ILRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Medaka
Match: ENSORLT00000014777.2 (pep primary_assembly:ASM223467v1:14:21234245:21236569:-1 gene:ENSORLG00000027210.1 transcript:ENSORLT00000014777.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 163.31 bits (412), Expect = 2.431e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   12 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 93

[Close]

BLAST of Histone H4 vs. Ensembl Medaka
Match: ENSORLT00000014780.2 (pep primary_assembly:ASM223467v1:14:21236258:21241436:-1 gene:ENSORLG00000029258.1 transcript:ENSORLT00000014780.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.54 bits (410), Expect = 3.226e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:    8 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 89

[Close]

BLAST of Histone H4 vs. Ensembl Medaka
Match: ENSORLT00000000211.2 (histone H4 [Source:NCBI gene;Acc:101170646])

HSP 1 Score: 163.31 bits (412), Expect = 3.380e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Medaka
Match: ENSORLT00000042762.1 (histone H4 [Source:NCBI gene;Acc:101159884])

HSP 1 Score: 163.31 bits (412), Expect = 3.380e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Ensembl Medaka
Match: ENSORLT00000028618.1 (histone H4 [Source:NCBI gene;Acc:101168421])

HSP 1 Score: 163.31 bits (412), Expect = 3.380e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Planmine SMEST
Match: SMESG000070504.1 (SMESG000070504.1)

HSP 1 Score: 163.31 bits (412), Expect = 2.497e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Planmine SMEST
Match: SMESG000070501.1 (SMESG000070501.1)

HSP 1 Score: 163.31 bits (412), Expect = 2.497e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Planmine SMEST
Match: SMESG000054351.1 (SMESG000054351.1)

HSP 1 Score: 163.31 bits (412), Expect = 2.497e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Planmine SMEST
Match: SMESG000048697.1 (SMESG000048697.1)

HSP 1 Score: 163.31 bits (412), Expect = 2.497e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

[Close]

BLAST of Histone H4 vs. Planmine SMEST
Match: SMESG000011051.1 (SMESG000011051.1)

HSP 1 Score: 163.31 bits (412), Expect = 2.497e-52
Identity = 82/82 (100.00%), Postives = 82/82 (100.00%), Query Frame = 1

Query:  142 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 387
            VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
Sbjct:   22 VLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG 103

The following BLAST results are available for this feature:

BLAST of Histone H4 vs. Ensembl Human
BLAST of Histone H4 vs. Ensembl Celegans
BLAST of Histone H4 vs. Ensembl Fly
BLAST of Histone H4 vs. Ensembl Zebrafish
BLAST of Histone H4 vs. Ensembl Xenopus
BLAST of Histone H4 vs. Ensembl Mouse
BLAST of Histone H4 vs. UniProt/SwissProt
BLAST of Histone H4 vs. TrEMBL
BLAST of Histone H4 vs. Ensembl Cavefish
BLAST of Histone H4 vs. Ensembl Sea Lamprey
BLAST of Histone H4 vs. Ensembl Yeast
BLAST of Histone H4 vs. Ensembl Nematostella
BLAST of Histone H4 vs. Ensembl Medaka
BLAST of Histone H4 vs. Planmine SMEST

BLAST of Histone H4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H4C9	6.308e-52	100.00	H4 clustered histone 9 [Source:HGNC Symbol;Acc:HGN...	[more]
H4C15	6.308e-52	100.00	H4 clustered histone 15 [Source:HGNC Symbol;Acc:HG...	[more]
H4C15	6.308e-52	100.00	H4 clustered histone 15 [Source:HGNC Symbol;Acc:HG...	[more]
H4C15	6.308e-52	100.00	H4 clustered histone 15 [Source:HGNC Symbol;Acc:HG...	[more]
H4C14	6.308e-52	100.00	H4 clustered histone 14 [Source:HGNC Symbol;Acc:HG...	[more]

BLAST of Histone H4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
his-67	8.940e-52	98.78	Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P6278...	[more]
his-64	8.940e-52	98.78	Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P6278...	[more]
his-60	8.940e-52	98.78	Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P6278...	[more]
his-56	8.940e-52	98.78	Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P6278...	[more]
his-50	8.940e-52	98.78	Histone H4 [Source:UniProtKB/Swiss-Prot;Acc:P6278...	[more]

BLAST of Histone H4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
His4:CG33899	3.484e-52	100.00	gene:FBgn0053899 transcript:FBtr0091903	[more]
His4:CG33897	3.484e-52	100.00	gene:FBgn0053897 transcript:FBtr0091901	[more]
His4r	3.484e-52	100.00	gene:FBgn0013981 transcript:FBtr0334029	[more]
His4r	3.484e-52	100.00	gene:FBgn0013981 transcript:FBtr0082962	[more]
His4r	3.484e-52	100.00	gene:FBgn0013981 transcript:FBtr0082963	[more]

BLAST of Histone H4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hist1h4l	4.013e-52	100.00	histone 1, H4, like [Source:ZFIN;Acc:ZDB-GENE-0709...	[more]
hist1h4l	4.013e-52	100.00	histone 1, H4, like [Source:ZFIN;Acc:ZDB-GENE-0709...	[more]
zgc:153409	4.013e-52	100.00	zgc:153409 [Source:ZFIN;Acc:ZDB-GENE-060929-224]	[more]
hist1h4l	4.013e-52	100.00	histone 1, H4, like [Source:ZFIN;Acc:ZDB-GENE-0709...	[more]
hist1h4l	4.013e-52	100.00	histone 1, H4, like [Source:ZFIN;Acc:ZDB-GENE-0709...	[more]

BLAST of Histone H4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zbtb22	5.718e-52	100.00	zinc finger and BTB domain containing 22 [Source:X...	[more]
hist1h4c	5.718e-52	100.00	histone H4 [Source:NCBI gene;Acc:101732638]	[more]
hist1h4c	5.718e-52	100.00	H4 clustered histone 1 [Source:NCBI gene;Acc:54962...	[more]
cpa1	5.718e-52	100.00	carboxypeptidase A1 [Source:Xenbase;Acc:XB-GENE-96...	[more]
hist1h4c	5.718e-52	100.00	H4 clustered histone 1 [Source:NCBI gene;Acc:54962...	[more]

BLAST of Histone H4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
H4c14	4.331e-52	100.00	H4 clustered histone 14 [Source:MGI Symbol;Acc:MGI...	[more]
H4c9	4.331e-52	100.00	H4 clustered histone 9 [Source:MGI Symbol;Acc:MGI:...	[more]
Hist1h4n	4.331e-52	100.00	histone cluster 1, H4n [Source:MGI Symbol;Acc:MGI:...	[more]
Hist1h4m	4.331e-52	100.00	histone cluster 1, H4m [Source:MGI Symbol;Acc:MGI:...	[more]
H4c12	4.331e-52	100.00	H4 clustered histone 12 [Source:MGI Symbol;Acc:MGI...	[more]

BLAST of Histone H4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6WV74\|H4_MYTCH	2.900e-51	100.00	Histone H4 OS=Mytilus chilensis OX=173667 PE=3 SV=...	[more]
sp\|Q28DR4\|H4_XENTR	3.029e-51	100.00	Histone H4 OS=Xenopus tropicalis OX=8364 GN=TGas00...	[more]
sp\|P62799\|H4_XENLA	3.029e-51	100.00	Histone H4 OS=Xenopus laevis OX=8355 PE=1 SV=2	[more]
sp\|P62798\|H4_XENBO	3.029e-51	100.00	Histone H4 OS=Xenopus borealis OX=8354 PE=3 SV=2	[more]
sp\|P62794\|H4_URECA	3.029e-51	100.00	Histone H4 OS=Urechis caupo OX=6431 PE=3 SV=2	[more]

BLAST of Histone H4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
E0VXR4	1.920e-50	88.89	Histone H4 OS=Pediculus humanus subsp. corporis OX...	[more]
A0A0D2MND9	2.076e-50	88.17	Histone H4 OS=Gossypium raimondii OX=29730 GN=B456...	[more]
A0A3S3SL30	2.787e-50	96.51	Histone H4 OS=Dinothrombium tinctorium OX=1965070 ...	[more]
A0A3Q2DQK7	6.048e-50	75.42	Histone H4 OS=Cyprinodon variegatus OX=28743 PE=3 ...	[more]
A0A1S3GPA9	6.528e-50	95.40	Histone H4 OS=Dipodomys ordii OX=10020 GN=LOC10600...	[more]

BLAST of Histone H4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000036719.1	1.923e-52	100.00	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000032266.1	2.446e-52	100.00	pep primary_assembly:Astyanax_mexicanus-2.0:21:100...	[more]
ENSAMXT00000025592.2	3.060e-52	100.00	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
ENSAMXT00000025764.2	3.401e-52	100.00	histone H4 [Source:NCBI gene;Acc:111190747]	[more]
ENSAMXT00000043832.1	8.727e-52	98.78	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Histone H4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ENSPMAT00000002372.1	4.333e-38	80.25	pep scaffold:Pmarinus_7.0:GL476925:46740:47638:1 g...	[more]
ENSPMAT00000002391.1	4.333e-38	80.25	pep scaffold:Pmarinus_7.0:GL476925:199603:200503:1...	[more]
ENSPMAT00000002392.1	4.333e-38	80.25	pep scaffold:Pmarinus_7.0:GL476925:215484:216380:1...	[more]
ENSPMAT00000002394.1	4.333e-38	80.25	pep scaffold:Pmarinus_7.0:GL476925:225178:226079:1...	[more]

BLAST of Histone H4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
HHF2	7.550e-49	90.24	Histone H4; core histone protein required for chro...	[more]
HHF1	7.550e-49	90.24	Histone H4; core histone protein required for chro...	[more]

BLAST of Histone H4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO40764	1.861e-52	98.78	Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0]	[more]
EDO27765	1.861e-52	98.78	Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0]	[more]
EDO38246	1.861e-52	98.78	Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0]	[more]
EDO30153	1.861e-52	98.78	Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0]	[more]
EDO46460	1.861e-52	98.78	Histone H4 [Source:UniProtKB/TrEMBL;Acc:A7RJL0]	[more]

BLAST of Histone H4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000014777.2	2.431e-52	100.00	pep primary_assembly:ASM223467v1:14:21234245:21236...	[more]
ENSORLT00000014780.2	3.226e-52	100.00	pep primary_assembly:ASM223467v1:14:21236258:21241...	[more]
ENSORLT00000000211.2	3.380e-52	100.00	histone H4 [Source:NCBI gene;Acc:101170646]	[more]
ENSORLT00000042762.1	3.380e-52	100.00	histone H4 [Source:NCBI gene;Acc:101159884]	[more]
ENSORLT00000028618.1	3.380e-52	100.00	histone H4 [Source:NCBI gene;Acc:101168421]	[more]

BLAST of Histone H4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000070504.1	2.497e-52	100.00	SMESG000070504.1	[more]
SMESG000070501.1	2.497e-52	100.00	SMESG000070501.1	[more]
SMESG000054351.1	2.497e-52	100.00	SMESG000054351.1	[more]
SMESG000048697.1	2.497e-52	100.00	SMESG000048697.1	[more]
SMESG000011051.1	2.497e-52	100.00	SMESG000011051.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025482 ID=SMED30025482|Name=Histone H4|organism=Schmidtea mediterranea sexual|type=transcript|length=552bp
TGTCATTATCAAAATATTTTCAATATATAATAAATCAGAAATCACTAAAC
AGTCATTACTAAACTATTCTAACTCAAAATGTCTGGTCGAGGAAAAGGAG
GAAAAGGCTTAGGTAAAGGTGGAGCTAAAAGACATAGAAAAGTTTTGCGA
GACAACATCCAAGGAATCACGAAACCAGCTATTAGAAGGTTAGCTCGCAG
AGGTGGCGTGAAAAGAATTTCTGGTCTTATCTATGAAGAAACTAGAGGTG
TTTTAAAGGTTTTCCTTGAAAACGTAATCAGAGATGCTGTTACTTACACT
GAACATGCTAAGCGTAAGACAGTCACAGCTATGGATGTTGTTTATGCACT
TAAACGACAAGGTCGTACTTTATACGGTTTTGGAGGGCCACAAATGTTGA
TTGTAGTGAATTGTTCAAATATTGTTATTCTATCTAGTAATTCTCAGCAA
TTTTATTAACGTTATTTAGAAATTAATTTTACAATTGCTAATTTCGAATG
TTATATCTGGTGTCAATGTTCAGTTATATTATTTTACAAATGACTTGAAA
TG

protein sequence of SMED30025482-orf-1

>SMED30025482-orf-1 ID=SMED30025482-orf-1|Name=SMED30025482-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=127bp
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGL
IYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYG
FGGPQMLIVVNCSNIVILSSNSQQFY*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0007268	chemical synaptic transmission
GO:0007411	axon guidance
GO:0007420	brain development
GO:0009416	response to light stimulus
GO:0006352	DNA-templated transcription, initiation
GO:0006334	nucleosome assembly

Vocabulary: **cellular component**
Term	Definition
GO:0042025	host cell nucleus
GO:0045202	synapse
GO:0005634	nucleus
GO:0000786	nucleosome
GO:0000788	nuclear nucleosome
GO:0005694	chromosome

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0002032	epidermal cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035425	CENP-T/H4_C
IPR004823	TAF_TATA-bd
IPR009072	Histone-fold
IPR019809	Histone_H4_CS
IPR001951	Histone_H4

Vocabulary: **molecular function**
Term	Definition
GO:0003677	DNA binding
GO:0046982	protein heterodimerization activity
GO:0042393	histone binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001951	Histone H4	PRINTS	PR00623	HISTONEH4	coord: 89..100 score: 97.79 coord: 62..76 score: 95.1 coord: 20..39 score: 93.38 coord: 5..16 score: 95.59 coord: 77..89 score: 92.76 coord: 40..60 score: 93.56
IPR001951	Histone H4	SMART	SM00417	h44	coord: 16..90 e-value: 2.9E-29 score: 113.2
IPR001951	Histone H4	CDD	cd00076	H4	coord: 18..101 e-value: 2.94184E-47 score: 144.951
IPR004823	TATA box binding protein associated factor (TAF)	SMART	SM00803	TAF_cls	coord: 28..93 e-value: 0.0086 score: 17.0
IPR035425	CENP-T/Histone H4, histone fold	PFAM	PF15511	CENP-T_C	coord: 36..96 e-value: 3.7E-8 score: 33.4
IPR009072	Histone-fold	GENE3D	G3DSA:1.10.20.10		coord: 2..103 e-value: 1.6E-60 score: 203.6
IPR009072	Histone-fold	SUPERFAMILY	SSF47113	Histone-fold	coord: 3..102
None	No IPR available	PANTHER	PTHR10484	HISTONE H4	coord: 1..103
None	No IPR available	PANTHER	PTHR10484:SF171		coord: 1..103
IPR019809	Histone H4, conserved site	PROSITE	PS00047	HISTONE_H4	coord: 15..19