disintegrin and metalloproteinase domain containing protein-2

Overview


Name	disintegrin and metalloproteinase domain containing protein-2 (AFJ24759.1)
Smed ID	SMED30025465
Length (bp)	3048

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of disintegrin and metalloproteinase domain containing protein-2 (SMED30025465) t-SNE clustered cells

Violin plots show distribution of expression levels for disintegrin and metalloproteinase domain containing protein-2 (SMED30025465) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of disintegrin and metalloproteinase domain containing protein-2 (SMED30025465) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025465

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
neoblast	SMED30025465	SMESG000076886.1	dd_Smed_v4_2341_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30025465	SMESG000076886.1	dd_Smed_v4_2341_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30025465	SMESG000076886.1	Contig55549	newmark_ests	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Match: ADAM10 (ADAM metallopeptidase domain 10 [Source:HGNC Symbol;Acc:HGNC:188])

HSP 1 Score: 459.914 bits (1182), Expect = 5.987e-148
Identity = 290/764 (37.96%), Postives = 408/764 (53.40%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPK---------RQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  ++F L +  D ++F    ++  ++K    +      GH++ +  S  +G+++DG F GFIQ+       G +YVE +  Y ++    FHS+IYH+            D+  P   G       H +     ++    + + T+ PQ +         R+KR+ S + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D+CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C +   CNG    CP S   P+ T C  +T+VC NGQC GSICE   G  EC+   S+    + +C V C + M  + C ST  +Q                  + + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   22 GNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQT-----RGGTFYVEPAERYIKDRTLPFHSVIYHED-----------DINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTADEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDECCFD--ANQPEGRKCKLKP----GKQ-----CSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKY-GLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHF-------------SGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 707

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Match: ADAM17 (ADAM metallopeptidase domain 17 [Source:HGNC Symbol;Acc:HGNC:195])

HSP 1 Score: 189.504 bits (480), Expect = 4.880e-49
Identity = 189/700 (27.00%), Postives = 296/700 (42.29%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT--NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHH------LNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQP--KRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSI---FTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRI-NTTDDCDPGQ----IRDSNPFCSANI-DVTNFLNLNSYVKHDD---FCLAYIFTYRDFNGGTLGLAWVAEPGGS--GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK--GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCR 2118
            L S + ++D L+ +    H   +R    S   + L + F A  ++F L L      F +N +++V D  +         DF    GH+  +  S+V   I D      I +D      G  Y     + F ND     ++ + S   D  N+  S L++P  CG+   +   ++    V           E P+    R KR       +  C L + +D   +            +Y+   E S+      + +     IY+NT++        + G G +++++RI  +  +  PG+    +  S P    +  DV   L   S+   ++    CLA++FTY+DF+ GTLGLA+V  P  +  GGVC K      G +N+   LN+G+ +  NYG  +  K + L   HE+GHNFG++HD D     +C P  ED  G Y+M+  A SGD ENN  FS CS+ SI +    +   +  CF  +    CGN   ++GE+CD G    +  D CC     NS C L          + V CS     CC N CQF+  Q  C+      C   +YC G  ++CP      D T C D  + CK+G+CI   CE  +    C+   ++       C V C++   +  C+   D +                    K + L+ G PC    G+CD   +C 
Sbjct:   35 LDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETL-LTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFF--TGHVVGEPDSRVLAHIRDDDVIIRINTD------GAEYNIEPLWRFVNDTKDKRMLVYKSE--DIKNV--SRLQSPKVCGYLKVDNEELLPKGLVDR---------EPPEELVHRVKRRADPDPMKNTCKLLVVADHRFY------------RYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAG----FKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNI--YLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL--AECAP-NEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKT---IESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCC-----NSDCTLK---------EGVQCSDRNSPCCKN-CQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGK-CKDGKCI-PFCEREQQLESCACNETDN-----SCKVCCRD--LSGRCVPYVDAE-------------------QKNLFLRKGKPC--TVGFCDMNGKCE 642

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Match: ADAM10 (ADAM metallopeptidase domain 10 [Source:HGNC Symbol;Acc:HGNC:188])

HSP 1 Score: 139.043 bits (349), Expect = 1.935e-37
Identity = 74/133 (55.64%), Postives = 93/133 (69.92%), Query Frame = 1

Query: 1063 RDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNR 1443
            RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L +
Sbjct:   20 RDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEK 145

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Match: ADAM15 (ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193])

HSP 1 Score: 95.5153 bits (236), Expect = 1.645e-19
Identity = 109/400 (27.25%), Postives = 161/400 (40.25%), Query Frame = 1

Query:  721 SDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLN-----LNSYVKHDDFCLAYIFTYRDFNGGTLGLAW---VAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCF------LHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCR-TKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCI--GSICESVRG 1869
            ++T   + ++   H + QKY   ++   +  + ++   A+  +T F+  N          RV  V +      D  +I   NP     + + NFL+     L   + HD    A + T   F+G T+G+A    +  P  SGGV   H                   ++L   S +A         HE+GH+ G  HD        C      P    IM AS    D      FS CSR ++ + L     G G+C       L    +FCGN   E GEQCDCG+   DC D CC+    +  C+L P            C+ S G CC N CQ +P    CR T+G+C    +C G  ++CP    + D   C     VC +G+C      C+S+ G
Sbjct:  194 TETKTVELVIVADHSEAQKY---RDFQHLLNRTLE--VALLLDTFFRPLN---------VRVALVGLEAWTQRDLVEI-SPNP----AVTLENFLHWRRAHLLPRLPHDS---AQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHS-----------------TSILGVASSIA---------HELGHSLGLDHD---LPGNSCPCPGPAPAKTCIMEAST---DFLPGLNFSNCSRRALEKAL---LDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCD----SLTCQLRPG---------AQCA-SDGPCCQN-CQLRPSGWQCRPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWG 520

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Match: ADAM15 (ADAM metallopeptidase domain 15 [Source:HGNC Symbol;Acc:HGNC:193])

HSP 1 Score: 95.9005 bits (237), Expect = 2.230e-19
Identity = 109/400 (27.25%), Postives = 161/400 (40.25%), Query Frame = 1

Query:  721 SDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLN-----LNSYVKHDDFCLAYIFTYRDFNGGTLGLAW---VAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCF------LHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCR-TKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCI--GSICESVRG 1869
            ++T   + ++   H + QKY   ++   +  + ++   A+  +T F+  N          RV  V +      D  +I   NP     + + NFL+     L   + HD    A + T   F+G T+G+A    +  P  SGGV   H                   ++L   S         + AHE+GH+ G  HD        C      P    IM AS    D      FS CSR ++ + L     G G+C       L    +FCGN   E GEQCDCG+   DC D CC+    +  C+L P            C+ S G CC N CQ +P    CR T+G+C    +C G  ++CP    + D   C     VC +G+C      C+S+ G
Sbjct:  210 TETKTVELVIVADHSEAQKY---RDFQHLLNRTLE--VALLLDTFFRPLN---------VRVALVGLEAWTQRDLVEI-SPNP----AVTLENFLHWRRAHLLPRLPHDS---AQLVTGTSFSGPTVGMAIQNSICSPDFSGGVNMDHS-----------------TSILGVAS---------SIAHELGHSLGLDHD---LPGNSCPCPGPAPAKTCIMEAST---DFLPGLNFSNCSRRALEKAL---LDGMGSCLFERLPSLPPMAAFCGNMFVEPGEQCDCGFL-DDCVDPCCD----SLTCQLRPG---------AQCA-SDGPCCQN-CQLRPSGWQCRPTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYAQQCQSLWG 536

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Match: sup-17 (Disintegrin and metalloproteinase domain-containing protein 10 homolog [Source:UniProtKB/Swiss-Prot;Acc:G5EFD9])

HSP 1 Score: 451.055 bits (1159), Expect = 5.997e-143
Identity = 299/813 (36.78%), Postives = 435/813 (53.51%), Query Frame = 1

Query:   43 KLETFILLILCIAASGF-SLSSFIKNFDKLNYNTNH-----KRFRRS--ATDSLQKQPLNIFFQAFTKNFLLNLYE-DDTVFYKNTEILVNDKSHHLNDFIP----VKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEND---PGFHSIIYHDSHLHDSHNLNYSDLKNPS----FCGWTNSNISHVMHLASVQHNKNKINDF-----TERPQPKRQKRSVSNKGNQYV--CNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIR--DSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP--GGSGGVCEKHRMMQEGSQN-VKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTK---------------GSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQ---DKCCNPKMSN-----SPCKLTPKILINKQWKPVYCSPSAGECCTND-CQF--QPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKP-IQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNP 2304
            +L+  + LI C+       L++FI NF+ LNY   H      R +RS  +  S  ++P+   F A+ + F + L+  DD++F+++    ++D      D  P     +G+L +D +S V+G++ DGVF G IQ+ +  +    Y ++ ++ YFE D     +HSIIY D  ++        D +N S     CG++    S V    +   N  +  DF     T   + KR      + G  +V  C+L++Q+D  L++ I  +           +EI S+F  H++    IY+ TNF   NG     G+ F + R  I T D CD G+ +    NPFC  N+DV+NFLNLNS   H  FCLAY  T+RDF GGTLGLAWVA P    +GG+C+ H+   EGS+  V +SLNTGIVTL+NYG+ V  +VSQLT AHE+GHNFGS HD       +C P +  P GN+IMFASATSGDK NN KFS CS  +I+ +L  V K               G  NCF  +  +FCGN++ E GE+CDCG+S  DC    DKCC P  +       PCK  P            CSPS G CC  D C    +  + +CR + EC     C+G + +CP S    D   CQD+T+VC +GQC GS+C ++ G  +C +   +    + +CF+AC   + +  C S+  L      R  +     + +  +KP + L  G+PC+NY GYCD F +CRSV+A+GPLAR+KNL+F+   +    +W    WW V +  +  ++ + +F+K  +  TPS+NP
Sbjct:    8 RLQLVVTLIFCLFFENVNGLNNFIDNFETLNYRATHVANQVTRRKRSIDSAASHYQEPIGFRFNAYNRTFHVQLHPIDDSLFHEDH---MSDVDGGYADIKPSHFLYEGYLKDDPNSHVHGSVFDGVFEGHIQTGEGRR----YSIDKAAKYFERDDRPTQYHSIIYRDDEINHRKWRVKRDAENLSEQMQGCGFS----SRVRREMTDVQNSGESTDFFTNYMTMGGRSKRANTLRDHDGLYFVRTCSLYMQADHKLYEHIR-MKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNF---NG---IKGLHFVIQRTSIYTPDSCDRGRAKTDSDNPFCEENVDVSNFLNLNSQRNHSAFCLAYALTFRDFVGGTLGLAWVASPQFNTAGGICQVHQRYNEGSRGWVYRSLNTGIVTLVNYGNRVPARVSQLTLAHEIGHNFGSPHDFP----AECQPGL--PDGNFIMFASATSGDKPNNGKFSPCSVKNISAVLAVVLKSMPVDPTRNASPVGIGKRNCFQERTSAFCGNQIYEPGEECDCGFSQADCDQMGDKCCVPHEARGNGGPGPCKRKPG---------AQCSPSQGYCCNPDTCSLHGKNEEKICRQESECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVC-AMFGLEDCFLTEGKA---DELCFLAC---IKDGKCTSSVHLPEFSANRTNF----LQNMRKDKPGLILHPGSPCNNYKGYCDIFRKCRSVDANGPLARLKNLLFNKRTIETLTQWAQDNWWVVGVGGLVFLVIMALFVKCCAVHTPSTNP 776

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Match: adm-4 (Disintegrin and metalloproteinase domain-containing protein 17 homolog [Source:UniProtKB/Swiss-Prot;Acc:Q94316])

HSP 1 Score: 118.627 bits (296), Expect = 4.196e-27
Identity = 157/632 (24.84%), Postives = 258/632 (40.82%), Query Frame = 1

Query:  151 RFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDG-VFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASV----QHNKNKINDFTERPQ----PKRQKRSVSN-KGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDD-----KYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANI-DVTNFLNLNSYVK-HDDFCLAYIFTYRDFNG-GTLGLAWVAEPG---GSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHD----DDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGS-GNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGE--CHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKE-NMTNAP 1959
            RF+RS   S+      + F+   + ++++L  + + F++N ++   D        +P   ++         GT+ +    R  +   ++N   G       S YF +D           HL  S+    SD   P   G+  S++   + L+++    Q +  + N F +  +    P  +++ V N K N+  C L L +D        S + I G+    I  ++      +     IY   N+     DD     ++  +GF +  +++      D     DS+    + I +V   L   ++ +   DFCL ++ T R F    TLGLA+V+       +GG+C K          +   L+T           +  K   +  +HE GH +G+ HD     D  + ++C P  ++  G Y+M   A  G   NN  FS CSR    +L+  V  G   +CF  +  SFCGN + EDGE+CD G  + D +  CC     +  C+L              CSP    CCT  CQF    H+C       C   A CNG   +CP +  V D  +C +    C NG C+   CE +    +  I        E+ C + C++ N T AP
Sbjct:   33 RFQRSTRQSV------VHFEFLDQEYVVDLEPNHSTFHENFKVFTQDGPQ----IVPRDEYI---------GTVREPRAGRAVLTQLEENVYIG-------SLYFVDDT---------LHLEPSYPHQLSDDLGP-VVGYFESDLDLNLDLSAMPVRNQVSFRRANPFLKHRRAIAIPSDRRKDVLNVKRNR--CTLKLVAD-------YSFYSIFGKNNTGI--VTKFLVNMIARVNEIYTPINWDVGKEDDISGRGRFQNMGFSIKEIKV-----LDRPNASDSHYNSYSRIWEVERLLREFAFAEGSKDFCLVHLVTARTFREVATLGLAYVSYKKWDETAGGICSKQETFNGRVAYINVLLSTSFANSEQSTYPLITKEIDIVVSHEYGHAWGATHDPTIDSDDPDVEECSPNDQN-GGKYLMSQYAQKGYDANNVLFSPCSR----KLIRDVLIGKWESCFQEEMTSFCGNGIVEDGEECDNGVDT-DNEFNCC-----DKFCRLAVG---------AKCSPLNHICCTPTCQFHNSTHVCLPGDSLLCKADAVCNGFSGECPSAPPVRDGQECLEGGE-CLNGVCL-PFCEKMSIGKKSCICED----LELSCRLCCRDYNGTCAP 586

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Match: adm-2 (ADAM (Disintegrin plus metalloprotease) family [Source:UniProtKB/TrEMBL;Acc:G5EDW5])

HSP 1 Score: 67.781 bits (164), Expect = 3.489e-11
Identity = 82/295 (27.80%), Postives = 114/295 (38.64%), Query Frame = 1

Query:  991 VTNFLNLNSYVKHDDFC-LAYIFTYRDFNGGTLGLAW---VAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEG-----SFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQHLCRTK-GECHKAAYCNGTHTKCPKSKKVPDLTKCQ-DNTRVCKNGQC 1839
            + NF+     +  D F    Y+ T   F+ G +G A+   +     SGG+   H              N  + T+              TFAHE+GH FG  HD + K+   C      P    IM  +  SG  E    +S CS  ++A   NR   G   C  ++ G     + CGN + E GE+CDCG     C + CCN     S CKL  +              ++G+CC    C+ +P   +CR   G C    YCNG    CP    V +   C       C  G C
Sbjct:  246 LNNFMEYKKIMLKDHFFDTGYLMTTLKFDEGVVGKAYKGTMCSYDYSGGIYVDHN-------------NDTVETVA-------------TFAHELGHTFGMDHDPNDKDVCYC------PMPRCIM--NPQSGHME---VWSECSVKNLASGFNR---GIDLCLFNEPGKKPSDAKCGNGIVEPGEECDCG--PLKCDNHCCN----GSTCKLIGEAEC-----------ASGDCCDLKTCKPKPRATVCRAAIGICDLDEYCNGETNDCPADFFVQNAALCPGKENEFCYEGGC 483

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Match: adm-2 (ADAM (Disintegrin plus metalloprotease) family [Source:UniProtKB/TrEMBL;Acc:G5EDW5])

HSP 1 Score: 67.781 bits (164), Expect = 3.555e-11
Identity = 82/295 (27.80%), Postives = 114/295 (38.64%), Query Frame = 1

Query:  991 VTNFLNLNSYVKHDDFC-LAYIFTYRDFNGGTLGLAW---VAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEG-----SFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQHLCRTK-GECHKAAYCNGTHTKCPKSKKVPDLTKCQ-DNTRVCKNGQC 1839
            + NF+     +  D F    Y+ T   F+ G +G A+   +     SGG+   H              N  + T+              TFAHE+GH FG  HD + K+   C      P    IM  +  SG  E    +S CS  ++A   NR   G   C  ++ G     + CGN + E GE+CDCG     C + CCN     S CKL  +              ++G+CC    C+ +P   +CR   G C    YCNG    CP    V +   C       C  G C
Sbjct:  246 LNNFMEYKKIMLKDHFFDTGYLMTTLKFDEGVVGKAYKGTMCSYDYSGGIYVDHN-------------NDTVETVA-------------TFAHELGHTFGMDHDPNDKDVCYC------PMPRCIM--NPQSGHME---VWSECSVKNLASGFNR---GIDLCLFNEPGKKPSDAKCGNGIVEPGEECDCG--PLKCDNHCCN----GSTCKLIGEAEC-----------ASGDCCDLKTCKPKPRATVCRAAIGICDLDEYCNGETNDCPADFFVQNAALCPGKENEFCYEGGC 483

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Match: unc-71 (Disintegrin and metalloproteinase domain-containing protein unc-71 [Source:UniProtKB/Swiss-Prot;Acc:G5EFD5])

HSP 1 Score: 54.299 bits (129), Expect = 4.893e-7
Identity = 52/183 (28.42%), Postives = 77/183 (42.08%), Query Frame = 1

Query: 1396 KFSVCSRDSIARLLNRVTKGSGNCFLHQ-----EGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCR-TKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCF 1926
            +FS CS   +AR+      G+  C L++     E   CGN + +  E+CDCG S ++CQD CC+P      C L P           +   +A   C + C+ +     CR +K  C  A  C+G    CP    + D T C  + + C  G C  S  +  + W        E    E +CF
Sbjct:  406 QFSKCS---VARMHGIWQDGNIQCLLNKPFQVSELRECGNGVVDGSEECDCG-SRENCQDPCCDPLT----CTLRP-----------HAQCAAHHKCCHRCELRKAGDTCRSSKSPCDVAEQCDGKSGDCPPDGHLIDGTVCGTDGQ-CWRGNCSDSHQQCQKLWGR------EARVAEPVCF 562

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Match: kuz (gene:FBgn0259984 transcript:FBtr0100660)

HSP 1 Score: 397.512 bits (1020), Expect = 4.702e-121
Identity = 233/560 (41.61%), Postives = 330/560 (58.93%), Query Frame = 1

Query:  691 NQYVCNLFLQSDTFLWDKIMS--LHHIKGQKY----LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGS----QNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSG-NCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKM-SNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSE--KVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRK 2316
            N+  C+L++Q+D  +W  I      H +G+KY       +EI+S+   HV     IY+NT   KF+G  ++  I F V R++I+    C        N FC+ ++DV+NFLNL+S   H DFCLAY+FTYRDF GGTLGLAWVA   G SGG+CEK++   E      Q+ K+SLNTGI+T +NY S V  KVSQLT AHE+GHNFGS HD      Q+C P      GNYIMFASATSGD+ NN+KFS CS  +I+ +L+ +   +  +CF   EG+FCGNK+ E GE+CDCG++ ++C+DKCC P++ S     L        +     CSPS G CC +N C F P  +   C+ + EC  ++ CNGT  +CP+ +   D T C + T +C  G+C GS C  +    +C +  +    V+   +C +AC++    + C ST +   K  +++               I L+ G+PCDN+ GYCD FL+CR+V+ADGPL R+KNL+ +   L     WI+  W+ V+L+ V  I+ +G F+K  +  TPSSNPK R+
Sbjct:  408 NKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT---KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD----YPQECRP--GGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPC-LLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQK-------------GGISLQPGSPCDNFQGYCDVFLKCRAVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRR 944

HSP 2 Score: 52.373 bits (124), Expect = 2.419e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYN-----TNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF 462
            L+ +I +++ LNY+      +H R RRS T   + Q +++ F +  ++F L L  D   F    +   +     ++     +G +  D +S V+G+I +GVF G I +++       YYVEH+ +YF
Sbjct:   37 LNEYISHYETLNYDHEHIRASHNRARRSVT---KDQYVHLKFASHGRDFHLRLKRDLNTFSNKLDFYDSKGPIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERD-----AYYVEHAKHYF 155

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Match: kuz (gene:FBgn0259984 transcript:FBtr0342903)

HSP 1 Score: 396.741 bits (1018), Expect = 3.095e-120
Identity = 233/560 (41.61%), Postives = 330/560 (58.93%), Query Frame = 1

Query:  691 NQYVCNLFLQSDTFLWDKIMS--LHHIKGQKY----LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGS----QNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSG-NCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKM-SNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSE--KVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRK 2316
            N+  C+L++Q+D  +W  I      H +G+KY       +EI+S+   HV     IY+NT   KF+G  ++  I F V R++I+    C        N FC+ ++DV+NFLNL+S   H DFCLAY+FTYRDF GGTLGLAWVA   G SGG+CEK++   E      Q+ K+SLNTGI+T +NY S V  KVSQLT AHE+GHNFGS HD      Q+C P      GNYIMFASATSGD+ NN+KFS CS  +I+ +L+ +   +  +CF   EG+FCGNK+ E GE+CDCG++ ++C+DKCC P++ S     L        +     CSPS G CC +N C F P  +   C+ + EC  ++ CNGT  +CP+ +   D T C + T +C  G+C GS C  +    +C +  +    V+   +C +AC++    + C ST +   K  +++               I L+ G+PCDN+ GYCD FL+CR+V+ADGPL R+KNL+ +   L     WI+  W+ V+L+ V  I+ +G F+K  +  TPSSNPK R+
Sbjct:  408 NKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT---KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD----YPQECRP--GGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPC-LLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQK-------------GGISLQPGSPCDNFQGYCDVFLKCRAVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRR 944

HSP 2 Score: 52.7582 bits (125), Expect = 2.053e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYN-----TNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF 462
            L+ +I +++ LNY+      +H R RRS T   + Q +++ F +  ++F L L  D   F    +   +     ++     +G +  D +S V+G+I +GVF G I +++       YYVEH+ +YF
Sbjct:   37 LNEYISHYETLNYDHEHIRASHNRARRSVT---KDQYVHLKFASHGRDFHLRLKRDLNTFSNKLDFYDSKGPIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERD-----AYYVEHAKHYF 155

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Match: kuz (gene:FBgn0259984 transcript:FBtr0301412)

HSP 1 Score: 397.512 bits (1020), Expect = 5.411e-120
Identity = 233/560 (41.61%), Postives = 330/560 (58.93%), Query Frame = 1

Query:  691 NQYVCNLFLQSDTFLWDKIMS--LHHIKGQKY----LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGS----QNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSG-NCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKM-SNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSE--KVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRK 2316
            N+  C+L++Q+D  +W  I      H +G+KY       +EI+S+   HV     IY+NT   KF+G  ++  I F V R++I+    C        N FC+ ++DV+NFLNL+S   H DFCLAY+FTYRDF GGTLGLAWVA   G SGG+CEK++   E      Q+ K+SLNTGI+T +NY S V  KVSQLT AHE+GHNFGS HD      Q+C P      GNYIMFASATSGD+ NN+KFS CS  +I+ +L+ +   +  +CF   EG+FCGNK+ E GE+CDCG++ ++C+DKCC P++ S     L        +     CSPS G CC +N C F P  +   C+ + EC  ++ CNGT  +CP+ +   D T C + T +C  G+C GS C  +    +C +  +    V+   +C +AC++    + C ST +   K  +++               I L+ G+PCDN+ GYCD FL+CR+V+ADGPL R+KNL+ +   L     WI+  W+ V+L+ V  I+ +G F+K  +  TPSSNPK R+
Sbjct:  408 NKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT---KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD----YPQECRP--GGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPC-LLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQK-------------GGISLQPGSPCDNFQGYCDVFLKCRAVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRR 944

HSP 2 Score: 52.7582 bits (125), Expect = 2.220e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYN-----TNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF 462
            L+ +I +++ LNY+      +H R RRS T   + Q +++ F +  ++F L L  D   F    +   +     ++     +G +  D +S V+G+I +GVF G I +++       YYVEH+ +YF
Sbjct:   37 LNEYISHYETLNYDHEHIRASHNRARRSVT---KDQYVHLKFASHGRDFHLRLKRDLNTFSNKLDFYDSKGPIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERD-----AYYVEHAKHYF 155

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Match: kuz (gene:FBgn0259984 transcript:FBtr0080509)

HSP 1 Score: 397.127 bits (1019), Expect = 9.750e-120
Identity = 233/560 (41.61%), Postives = 330/560 (58.93%), Query Frame = 1

Query:  691 NQYVCNLFLQSDTFLWDKIMS--LHHIKGQKY----LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGS----QNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSG-NCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKM-SNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSE--KVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRK 2316
            N+  C+L++Q+D  +W  I      H +G+KY       +EI+S+   HV     IY+NT   KF+G  ++  I F V R++I+    C        N FC+ ++DV+NFLNL+S   H DFCLAY+FTYRDF GGTLGLAWVA   G SGG+CEK++   E      Q+ K+SLNTGI+T +NY S V  KVSQLT AHE+GHNFGS HD      Q+C P      GNYIMFASATSGD+ NN+KFS CS  +I+ +L+ +   +  +CF   EG+FCGNK+ E GE+CDCG++ ++C+DKCC P++ S     L        +     CSPS G CC +N C F P  +   C+ + EC  ++ CNGT  +CP+ +   D T C + T +C  G+C GS C  +    +C +  +    V+   +C +AC++    + C ST +   K  +++               I L+ G+PCDN+ GYCD FL+CR+V+ADGPL R+KNL+ +   L     WI+  W+ V+L+ V  I+ +G F+K  +  TPSSNPK R+
Sbjct:  408 NKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT---KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD----YPQECRP--GGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPC-LLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQK-------------GGISLQPGSPCDNFQGYCDVFLKCRAVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRR 944

HSP 2 Score: 52.373 bits (124), Expect = 2.303e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYN-----TNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF 462
            L+ +I +++ LNY+      +H R RRS T   + Q +++ F +  ++F L L  D   F    +   +     ++     +G +  D +S V+G+I +GVF G I +++       YYVEH+ +YF
Sbjct:   37 LNEYISHYETLNYDHEHIRASHNRARRSVT---KDQYVHLKFASHGRDFHLRLKRDLNTFSNKLDFYDSKGPIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERD-----AYYVEHAKHYF 155

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Match: kuz (gene:FBgn0259984 transcript:FBtr0080510)

HSP 1 Score: 397.127 bits (1019), Expect = 9.750e-120
Identity = 233/560 (41.61%), Postives = 330/560 (58.93%), Query Frame = 1

Query:  691 NQYVCNLFLQSDTFLWDKIMS--LHHIKGQKY----LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGS----QNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSG-NCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKM-SNSPCKLTPKILINKQWKPVYCSPSAGECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSE--KVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRK 2316
            N+  C+L++Q+D  +W  I      H +G+KY       +EI+S+   HV     IY+NT   KF+G  ++  I F V R++I+    C        N FC+ ++DV+NFLNL+S   H DFCLAY+FTYRDF GGTLGLAWVA   G SGG+CEK++   E      Q+ K+SLNTGI+T +NY S V  KVSQLT AHE+GHNFGS HD      Q+C P      GNYIMFASATSGD+ NN+KFS CS  +I+ +L+ +   +  +CF   EG+FCGNK+ E GE+CDCG++ ++C+DKCC P++ S     L        +     CSPS G CC +N C F P  +   C+ + EC  ++ CNGT  +CP+ +   D T C + T +C  G+C GS C  +    +C +  +    V+   +C +AC++    + C ST +   K  +++               I L+ G+PCDN+ GYCD FL+CR+V+ADGPL R+KNL+ +   L     WI+  W+ V+L+ V  I+ +G F+K  +  TPSSNPK R+
Sbjct:  408 NKNTCSLYIQTDPLIWRHIREGIADHDRGRKYEVDEKTREEITSLIAHHVTAVNYIYRNT---KFDGRTEHRNIRFEVQRIKIDDDSACRNSYNGPHNAFCNEHMDVSNFLNLHSLEDHSDFCLAYVFTYRDFTGGTLGLAWVASASGASGGICEKYKTYTETVGGQYQSTKRSLNTGIITFVNYNSRVPPKVSQLTLAHEIGHNFGSPHD----YPQECRP--GGLNGNYIMFASATSGDRPNNSKFSPCSIRNISNVLDVLVGNTKRDCFKASEGAFCGNKIVESGEECDCGFNEEECKDKCCYPRLISEYDQSLNSSAKGCTRRAKTQCSPSQGPCCLSNSCTFVPTSYHQKCKEETECSWSSTCNGTTAECPEPRHRDDKTMCNNGTALCIRGECSGSPC-LLWNMTKCFLTSTTLPHVSKRKLCDLACQDGNDTSTCRSTSEFADKYNIQK-------------GGISLQPGSPCDNFQGYCDVFLKCRAVDADGPLLRLKNLLLNRKTLQTVAEWIVDNWYLVVLMGVAFIVVMGSFIKCCAVHTPSSNPKKRR 944

HSP 2 Score: 52.373 bits (124), Expect = 2.303e-6
Identity = 36/127 (28.35%), Postives = 65/127 (51.18%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYN-----TNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF 462
            L+ +I +++ LNY+      +H R RRS T   + Q +++ F +  ++F L L  D   F    +   +     ++     +G +  D +S V+G+I +GVF G I +++       YYVEH+ +YF
Sbjct:   37 LNEYISHYETLNYDHEHIRASHNRARRSVT---KDQYVHLKFASHGRDFHLRLKRDLNTFSNKLDFYDSKGPIDVSTDHIYEGEVIGDRNSYVFGSIHNGVFEGKIITERD-----AYYVEHAKHYF 155

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Match: adam10a (ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:ZDB-GENE-040917-2])

HSP 1 Score: 444.506 bits (1142), Expect = 5.774e-142
Identity = 292/785 (37.20%), Postives = 419/785 (53.38%), Query Frame = 1

Query:   31 MNNIKLETFILLIL--CIAAS----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF--ENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKIN-----DFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            MN + +  F LLIL  C++ S    G  L+ +I++++ L+Y+T+     H+R +R+   S Q Q +++ F A  ++F L +  D ++F  N ++ V+      +      G ++ +  S  +G++VDG F GFI+S       G YYVE S  Y   +N P +HS+IYH+  +   H       K  S  G  + ++   M  + AS      + N     +  + P   R +R+   + N   C LF+Q+D   +          G +   I +ISS    HV+   +IYQ T+FQ          I F V R++INTT D    +   SNPF   NI V  FL LNS   HD++CLAY+FT RDF+ G LGLAWV  P GS GG+CEK++   +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       DC P       +  KGNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K    CF+      CGN L E  E+CDCGY+ + C+D+CC    +     CKL P+    +    V+CSPS G CCT  C ++   + CR + +C     CNG   +CP S    + T C  NT+VC NG C GSICE  +    C+    +      +C V C E    + C ST   +                  +NK I L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  + T    WI++ WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    1 MNLLDMVLFKLLILLYCLSDSNGQYGKPLNKYIRHYEGLSYDTDVLHSKHQRAKRAL--SHQDQFIHLEFHAHGRHFNLRMKRDTSLFTHNLKVEVSGVEVPYDTSHIYTGEIYGEKDSLTHGSVVDGKFEGFIKSHH-----GTYYVEPSERYLKDQNVP-YHSVIYHEDDIDYPH-------KYGSEGGCADHSVFERMKKYQASAMEEPTQTNHIIDEEVADGPVILRTRRAAQAEKN--TCQLFIQTDHLFFKYY-------GSREAVIAQISS----HVKAINSIYQGTDFQGIRN------ISFMVKRIKINTTID----EKDSSNPFRFGNIGVEKFLELNSEQNHDEYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKNKQYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHD----SGSDCTPGESKTTDQKEKGNYIMYARATSGDKFNNNKFSICSVRNISQVLD---KKRSACFVESGQPICGNGLVETNEECDCGYNDQ-CKDQCCYSADEPEGKKCKLKPE---TESKSKVFCSPSQGPCCTPQCTYR-TGNECRPESDCAFKGLCNGLSAQCPASTPKENYTACHANTQVCINGGCSGSICEKHK-LDVCTCATEDGKDDMELCHVCCMEKGKPSTCSSTSSERWA-------------SFFDNKVITLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYTSIAEWIVKHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 718

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Match: adam10a (ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:ZDB-GENE-040917-2])

HSP 1 Score: 444.121 bits (1141), Expect = 6.131e-142
Identity = 289/779 (37.10%), Postives = 415/779 (53.27%), Query Frame = 1

Query:   31 MNNIKLETFILLIL--CIAAS----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF--ENDPGFHSIIYHDSHLHDSHNL-NYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            MN + +  F LLIL  C++ S    G  L+ +I++++ L+Y+T+     H+R +R+   S Q Q +++ F A  ++F L +  D ++F  N ++ V+      +      G ++ +  S  +G++VDG F GFI+S       G YYVE S  Y   +N P +HS+IYH+  +   H   +     + S         +  M   + Q N     +  + P   R +R+   + N   C LF+Q+D   +          G +   I +ISS    HV+   +IYQ T+FQ          I F V R++INTT D    +   SNPF   NI V  FL LNS   HD++CLAY+FT RDF+ G LGLAWV  P GS GG+CEK++   +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       DC P       +  KGNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K    CF+      CGN L E  E+CDCGY+ + C+D+CC    +     CKL P+    +    V+CSPS G CCT  C ++   + CR + +C     CNG   +CP S    + T C  NT+VC NG C GSICE  +    C+    +      +C V C E    + C ST   +                  +NK I L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  + T    WI++ WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    1 MNLLDMVLFKLLILLYCLSDSNGQYGKPLNKYIRHYEGLSYDTDVLHSKHQRAKRAL--SHQDQFIHLEFHAHGRHFNLRMKRDTSLFTHNLKVEVSGVEVPYDTSHIYTGEIYGEKDSLTHGSVVDGKFEGFIKSHH-----GTYYVEPSERYLKDQNVP-YHSVIYHEDDIDYPHKYGSEGGCADHSVFERMKKYQASAMEEPTQQTNHIIDEEVADGPVILRTRRAAQAEKN--TCQLFIQTDHLFFKYY-------GSREAVIAQISS----HVKAINSIYQGTDFQGIRN------ISFMVKRIKINTTID----EKDSSNPFRFGNIGVEKFLELNSEQNHDEYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKNKQYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHD----SGSDCTPGESKTTDQKEKGNYIMYARATSGDKFNNNKFSICSVRNISQVLD---KKRSACFVESGQPICGNGLVETNEECDCGYNDQ-CKDQCCYSADEPEGKKCKLKPE---TESKSKVFCSPSQGPCCTPQCTYR-TGNECRPESDCAFKGLCNGLSAQCPASTPKENYTACHANTQVCINGGCSGSICEKHK-LDVCTCATEDGKDDMELCHVCCMEKGKPSTCSSTSSERWA-------------SFFDNKVITLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYTSIAEWIVKHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 719

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Match: adam10a (ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:ZDB-GENE-040917-2])

HSP 1 Score: 436.032 bits (1120), Expect = 7.586e-139
Identity = 287/779 (36.84%), Postives = 411/779 (52.76%), Query Frame = 1

Query:   31 MNNIKLETFILLIL--CIAAS----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF--ENDPGFHSIIYHDSHLHDSHNL-NYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            MN + +  F LLIL  C++ S    G  L+ +I++++ L+Y+T+     H+R +R+   S Q Q +++ F A  ++F L +  D ++F  N ++ V+      +      G ++ +  S  +G++VDG F GFI+S       G YYVE S  Y   +N P +HS+IYH+  +   H   +     + S         +  M   + Q N     +  + P   R +R+   + N   C LF+Q+D   +          G +   I +ISS    HV+   +IYQ T+FQ          I F V R++INTT D    +   SNPF   NI V  FL LNS   HD++CLAY+FT RDF+ G LGLAWV  P GS GG+CEK++   +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       DC P       +  KGNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K    CF+      CGN L E  E+CDCGY+ + C+D+CC    +     CKL P+   N         PS G CCT  C ++   + CR + +C     CNG   +CP S    + T C  NT+VC NG C GSICE  +    C+    +      +C V C E    + C ST   +                  +NK I L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  + T    WI++ WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    1 MNLLDMVLFKLLILLYCLSDSNGQYGKPLNKYIRHYEGLSYDTDVLHSKHQRAKRAL--SHQDQFIHLEFHAHGRHFNLRMKRDTSLFTHNLKVEVSGVEVPYDTSHIYTGEIYGEKDSLTHGSVVDGKFEGFIKSHH-----GTYYVEPSERYLKDQNVP-YHSVIYHEDDIDYPHKYGSEGGCADHSVFERMKKYQASAMEEPTQQTNHIIDEEVADGPVILRTRRAAQAEKN--TCQLFIQTDHLFFKYY-------GSREAVIAQISS----HVKAINSIYQGTDFQGIRN------ISFMVKRIKINTTID----EKDSSNPFRFGNIGVEKFLELNSEQNHDEYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKNKQYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHD----SGSDCTPGESKTTDQKEKGNYIMYARATSGDKFNNNKFSICSVRNISQVLD---KKRSACFVESGQPICGNGLVETNEECDCGYNDQ-CKDQCCYSADEPEGKKCKLKPETESN---------PSQGPCCTPQCTYR-TGNECRPESDCAFKGLCNGLSAQCPASTPKENYTACHANTQVCINGGCSGSICEKHK-LDVCTCATEDGKDDMELCHVCCMEKGKPSTCSSTSSERWA-------------SFFDNKVITLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYTSIAEWIVKHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 713

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Match: adam10a (ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:ZDB-GENE-040917-2])

HSP 1 Score: 433.335 bits (1113), Expect = 7.038e-138
Identity = 285/778 (36.63%), Postives = 411/778 (52.83%), Query Frame = 1

Query:   46 LETFILLILCIAAS----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF--ENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKIN-----DFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            L   ++L+ C++ S    G  L+ +I++++ L+Y+T+     H+R +R+   S Q Q +++ F A  ++F L +  D ++F  N ++ V+      +      G ++ +  S  +G++VDG F GFI+S       G YYVE S  Y   +N P +HS+IYH+  +   H       K  S  G  + ++   M  + AS      + N     +  + P   R +R+   + N   C LF+Q+D   +          G +   I +ISS    HV+   +IYQ T+FQ          I F V R++INTT D    +   SNPF   NI V  FL LNS   HD++CLAY+FT RDF+ G LGLAWV  P GS GG+CEK++   +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       DC P       +  KGNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K    CF+      CGN L E  E+CDCGY+ + C+D+CC    +     CKL P+   N         PS G CCT  C ++   + CR + +C     CNG   +CP S    + T C  NT+VC NG C GSICE  +    C+    +      +C V C E    + C ST   +                  +NK I L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  + T    WI++ WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    3 LFKLLILLYCLSDSNGQYGKPLNKYIRHYEGLSYDTDVLHSKHQRAKRAL--SHQDQFIHLEFHAHGRHFNLRMKRDTSLFTHNLKVEVSGVEVPYDTSHIYTGEIYGEKDSLTHGSVVDGKFEGFIKSHH-----GTYYVEPSERYLKDQNVP-YHSVIYHEDDIDYPH-------KYGSEGGCADHSVFERMKKYQASAMEEPTQTNHIIDEEVADGPVILRTRRAAQAEKN--TCQLFIQTDHLFFKYY-------GSREAVIAQISS----HVKAINSIYQGTDFQGIRN------ISFMVKRIKINTTID----EKDSSNPFRFGNIGVEKFLELNSEQNHDEYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKNKQYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHD----SGSDCTPGESKTTDQKEKGNYIMYARATSGDKFNNNKFSICSVRNISQVLD---KKRSACFVESGQPICGNGLVETNEECDCGYNDQ-CKDQCCYSADEPEGKKCKLKPETESN---------PSQGPCCTPQCTYR-TGNECRPESDCAFKGLCNGLSAQCPASTPKENYTACHANTQVCINGGCSGSICEKHK-LDVCTCATEDGKDDMELCHVCCMEKGKPSTCSSTSSERWA-------------SFFDNKVITLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYTSIAEWIVKHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 707

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Match: adam10b (ADAM metallopeptidase domain 10b [Source:ZFIN;Acc:ZDB-GENE-071115-1])

HSP 1 Score: 360.918 bits (925), Expect = 2.391e-112
Identity = 234/633 (36.97%), Postives = 333/633 (52.61%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKE-ISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLV-----EDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNP--KMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKE 1941
            G  L+ +I++++ L+Y+T     +H+R +R+AT +  ++ L + F A  ++F L +  D  +F  + ++ V+ +    +      G ++ +  +  +G++ DG F GFI + +     G +YVE    Y ++ +  FHS+IYH+            D+   +    ++SN     HL  +           +     R+KR    + N   C LF+Q+D   +            KY   +E + +  + HV+   AIYQ T+F           I F V R+RINTT D    +   SNPF  ANI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK+++  +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       +C P       +  +GNYIM+A ATSGDK NNNKFSVCS  +I+++L    K  G+CF+      CGN L E GEQCDCGYS + C+D CC    +  N  CKL P  +         CSPS G CCT +C ++     CR + EC     C+G+  +CP S+   + T C  NT+VC NG C GSICE   G   C+    E      +C V C E
Sbjct:   30 GNPLNKYIRHYEGLSYDTEMLHSDHQRAKRAATHT--ERTLQLEFHAHGRHFNLRMRRDTGLFADDFKLEVSGQEMDYDTSHIYSGEIYGEQGTLTHGSVQDGRFEGFILTHR-----GTFYVEPVERYLQDKNVPFHSVIYHED-----------DIVTHTAVPRSSSNAVPPAHLPPLDLLLQDSPPAQDEDVLLRKKRMTQVEKN--TCQLFIQTDHLFY------------KYYKTREAVIAQISSHVKAIDAIYQGTDFMGIRN------ISFMVKRIRINTTSD----ERDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPAGSSGGICEKNKLYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS----GSECTPGESKSPDKKERGNYIMYARATSGDKLNNNKFSVCSIKNISQVLE---KKRGSCFVESGQPICGNGLVEPGEQCDCGYSDQ-CKDDCCYDANQPDNKKCKLKPGKV---------CSPSQGPCCTFECSYKGHNEKCREESECAHQGLCSGSSAQCPTSEPKANFTACHGNTQVCLNGGCSGSICEKY-GLEVCTCASVEGKDETELCHVCCME 599

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Match: dnajc24 (DnaJ heat shock protein family (Hsp40) member C24 [Source:Xenbase;Acc:XB-GENE-1016343])

HSP 1 Score: 451.055 bits (1159), Expect = 1.212e-144
Identity = 289/769 (37.58%), Postives = 411/769 (53.45%), Query Frame = 1

Query:   43 KLETFILLILCIAASGFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFT-ERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRIN-TTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            K E     IL +   G  L+ +I++++ LNYN +     H+R +R+   S + Q +++ FQA  + F L +  D ++F  + ++ V  ++   +      G L  +  +  +G++VDG F GFI++ +     G +Y+E S  +F+N    FHS++YH+  +   H       K  S  G  +S++   M  +  S Q    K  D     P   R+KR+   + N   C L++Q+D   + +          +   I +ISS    HV+    IYQ+T+F           I F V R+RIN T+D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CE++++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L     GN+IM+A ATSGDK NNNKFS+CS  +I+++L+   K   +CF+      CGN L E GEQCDCGYS + C+D CC    +N P  L   +   KQ     CSPS G CC + C F+     CR + +C K   CNG   +CP S    +LT+C   T+VC  GQC GSICE      EC+   S+    + +C V C E M    C ST     +   +              K I L+ G+PC+ + GYCD F+RCR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    6 KSEYSSYFILSLGHYGNPLNKYIRHYEGLNYNMDSLHQKHQRAKRAV--SQEDQFVHLDFQAHGRQFNLRMKRDTSLFSPDFKLEVGGETVDYDTSHIYTGQLFGEQGTLSHGSVVDGRFEGFIKTHQ-----GTFYLEPSERFFKNQAVPFHSVMYHEDDIKYPH-------KYGSEGGCADSSVFQRMKEYQMSAQEESEKHEDHEGSGPLILRKKRAAQAEKN--TCQLYIQTDHLFYKRYGET------REAVIAQISS----HVKAIDTIYQSTDFSGIRN------ISFMVKRIRINVTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKNLGFKENGNFIMYARATSGDKLNNNKFSICSVRNISQVLD---KKRNSCFVESGQPICGNGLVEQGEQCDCGYSDQ-CKDDCCYD--ANQPENLKCTLKPGKQ-----CSPSQGPCCNSGCTFKLRSEKCREESDCAKMGTCNGVSAQCPPSDPRDNLTECNRATQVCIKGQCSGSICEKY-DLEECTCGSSDGKDDKELCHVCCMEKMKPHTCASTGSEAWRAHFK-------------GKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 705

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Match: dnajc24 (DnaJ heat shock protein family (Hsp40) member C24 [Source:Xenbase;Acc:XB-GENE-1016343])

HSP 1 Score: 448.743 bits (1153), Expect = 1.554e-143
Identity = 290/773 (37.52%), Postives = 413/773 (53.43%), Query Frame = 1

Query:   43 KLETFILLILCIAASGFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFTER-----PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRIN-TTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            K E     IL +   G  L+ +I++++ LNYN +     H+R +R+   S + Q +++ FQA  + F L +  D ++F  + ++ V  ++   +      G L  +  +  +G++VDG F GFI++ +     G +Y+E S  +F+N    FHS++YH+  +   H       K  S  G  +S++   M  +  S Q    K +D  E      P   R+KR+   + N   C L++Q+D   + +          +   I +ISS    HV+    IYQ+T+F           I F V R+RIN T+D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CE++++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L     GN+IM+A ATSGDK NNNKFS+CS  +I+++L+   K   +CF+      CGN L E GEQCDCGYS + C+D CC    +N P  L   +   KQ     CSPS G CC + C F+     CR + +C K   CNG   +CP S    +LT+C   T+VC  GQC GSICE      EC+   S+    + +C V C E M    C ST     +   +              K I L+ G+PC+ + GYCD F+RCR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   10 KSEYSSYFILSLGHYGNPLNKYIRHYEGLNYNMDSLHQKHQRAKRAV--SQEDQFVHLDFQAHGRQFNLRMKRDTSLFSPDFKLEVGGETVDYDTSHIYTGQLFGEQGTLSHGSVVDGRFEGFIKTHQ-----GTFYLEPSERFFKNQAVPFHSVMYHEDDIKYPH-------KYGSEGGCADSSVFQRMKEYQMSAQEESEK-HDHKEDHEGSGPLILRKKRAAQAEKN--TCQLYIQTDHLFYKRYGET------REAVIAQISS----HVKAIDTIYQSTDFSGIRN------ISFMVKRIRINVTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKNLGFKENGNFIMYARATSGDKLNNNKFSICSVRNISQVLD---KKRNSCFVESGQPICGNGLVEQGEQCDCGYSDQ-CKDDCCYD--ANQPENLKCTLKPGKQ-----CSPSQGPCCNSGCTFKLRSEKCREESDCAKMGTCNGVSAQCPPSDPRDNLTECNRATQVCIKGQCSGSICEKY-DLEECTCGSSDGKDDKELCHVCCMEKMKPHTCASTGSEAWRAHFK-------------GKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 712

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Match: dnajc24 (DnaJ heat shock protein family (Hsp40) member C24 [Source:Xenbase;Acc:XB-GENE-1016343])

HSP 1 Score: 447.973 bits (1151), Expect = 1.857e-143
Identity = 282/762 (37.01%), Postives = 409/762 (53.67%), Query Frame = 1

Query:   61 LLILCIAASGFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRIN-TTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            + +L  +  G  L+ +I++++ LNYN +     H+R +R+   S + Q +++ FQA  + F L +  D ++F  + ++ V  ++   +      G L  +  +  +G++VDG F GFI++ +     G +Y+E S  +F+N    FHS++YH+  +   H       K  S  G  +S++   M  +  S Q    K   + E   P   ++  + +  +  C L++Q+D   + +          +   I +ISS    HV+    IYQ+T+F           I F V R+RIN T+D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CE++++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L     GN+IM+A ATSGDK NNNKFS+CS  +I+++L+   K   +CF+      CGN L E GEQCDCGYS + C+D CC    +N P  L   +   KQ     CSPS G CC + C F+     CR + +C K   CNG   +CP S    +LT+C   T+VC  GQC GSICE      EC+   S+    + +C V C E M    C ST     +   +              K I L+ G+PC+ + GYCD F+RCR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    1 MKMLSQSHYGNPLNKYIRHYEGLNYNMDSLHQKHQRAKRAV--SQEDQFVHLDFQAHGRQFNLRMKRDTSLFSPDFKLEVGGETVDYDTSHIYTGQLFGEQGTLSHGSVVDGRFEGFIKTHQ-----GTFYLEPSERFFKNQAVPFHSVMYHEDDIKYPH-------KYGSEGGCADSSVFQRMKEYQMSAQEESEKHVRYHEGSGPLILRKKRAAQAEKNTCQLYIQTDHLFYKRYGET------REAVIAQISS----HVKAIDTIYQSTDFSGIRN------ISFMVKRIRINVTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKNLGFKENGNFIMYARATSGDKLNNNKFSICSVRNISQVLD---KKRNSCFVESGQPICGNGLVEQGEQCDCGYSDQ-CKDDCCYD--ANQPENLKCTLKPGKQ-----CSPSQGPCCNSGCTFKLRSEKCREESDCAKMGTCNGVSAQCPPSDPRDNLTECNRATQVCIKGQCSGSICEKY-DLEECTCGSSDGKDDKELCHVCCMEKMKPHTCASTGSEAWRAHFK-------------GKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 695

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Match: dnajc24 (DnaJ heat shock protein family (Hsp40) member C24 [Source:Xenbase;Acc:XB-GENE-1016343])

HSP 1 Score: 444.121 bits (1141), Expect = 8.733e-142
Identity = 290/778 (37.28%), Postives = 415/778 (53.34%), Query Frame = 1

Query:   40 IKLETFILLILCIAASGF----SLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFTER-----PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRIN-TTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            + L   + L+   A SG      L+ +I++++ LNYN +     H+R +R+   S + Q +++ FQA  + F L +  D ++F  + ++ V  ++   +      G L  +  +  +G++VDG F GFI++ +     G +Y+E S  +F+N    FHS++YH+  +   H       K  S  G  +S++   M  +  S Q    K +D  E      P   R+KR+   + N   C L++Q+D   + +          +   I +ISS    HV+    IYQ+T+F           I F V R+RIN T+D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CE++++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L     GN+IM+A ATSGDK NNNKFS+CS  +I+++L+   K   +CF+      CGN L E GEQCDCGYS + C+D CC    +N P  L   +   KQ     CSPS G CC + C F+     CR + +C K   CNG   +CP S    +LT+C   T+VC  GQC GSICE      EC+   S+    + +C V C E M    C ST     +   +              K I L+ G+PC+ + GYCD F+RCR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   12 MALLRLVFLLSWAACSGGHYGNPLNKYIRHYEGLNYNMDSLHQKHQRAKRAV--SQEDQFVHLDFQAHGRQFNLRMKRDTSLFSPDFKLEVGGETVDYDTSHIYTGQLFGEQGTLSHGSVVDGRFEGFIKTHQ-----GTFYLEPSERFFKNQAVPFHSVMYHEDDIKYPH-------KYGSEGGCADSSVFQRMKEYQMSAQEESEK-HDHKEDHEGSGPLILRKKRAAQAEKN--TCQLYIQTDHLFYKRYGET------REAVIAQISS----HVKAIDTIYQSTDFSGIRN------ISFMVKRIRINVTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKNLGFKENGNFIMYARATSGDKLNNNKFSICSVRNISQVLD---KKRNSCFVESGQPICGNGLVEQGEQCDCGYSDQ-CKDDCCYD--ANQPENLKCTLKPGKQ-----CSPSQGPCCNSGCTFKLRSEKCREESDCAKMGTCNGVSAQCPPSDPRDNLTECNRATQVCIKGQCSGSICEKY-DLEECTCGSSDGKDDKELCHVCCMEKMKPHTCASTGSEAWRAHFK-------------GKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 719

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Match: dnajc24 (DnaJ heat shock protein family (Hsp40) member C24 [Source:Xenbase;Acc:XB-GENE-1016343])

HSP 1 Score: 443.351 bits (1139), Expect = 1.238e-141
Identity = 286/758 (37.73%), Postives = 408/758 (53.83%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFTER-----PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRIN-TTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ LNYN +     H+R +R+   S + Q +++ FQA  + F L +  D ++F  + ++ V  ++   +      G L  +  +  +G++VDG F GFI++ +     G +Y+E S  +F+N    FHS++YH+  +   H       K  S  G  +S++   M  +  S Q    K +D  E      P   R+KR+   + N   C L++Q+D   + +          +   I +ISS    HV+    IYQ+T+F           I F V R+RIN T+D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CE++++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L     GN+IM+A ATSGDK NNNKFS+CS  +I+++L+   K   +CF+      CGN L E GEQCDCGYS + C+D CC    +N P  L   +   KQ     CSPS G CC + C F+     CR + +C K   CNG   +CP S    +LT+C   T+VC  GQC GSICE      EC+   S+    + +C V C E M    C ST     +   +              K I L+ G+PC+ + GYCD F+RCR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   19 GNPLNKYIRHYEGLNYNMDSLHQKHQRAKRAV--SQEDQFVHLDFQAHGRQFNLRMKRDTSLFSPDFKLEVGGETVDYDTSHIYTGQLFGEQGTLSHGSVVDGRFEGFIKTHQ-----GTFYLEPSERFFKNQAVPFHSVMYHEDDIKYPH-------KYGSEGGCADSSVFQRMKEYQMSAQEESEK-HDHKEDHEGSGPLILRKKRAAQAEKN--TCQLYIQTDHLFYKRYGET------REAVIAQISS----HVKAIDTIYQSTDFSGIRN------ISFMVKRIRINVTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKNLGFKENGNFIMYARATSGDKLNNNKFSICSVRNISQVLD---KKRNSCFVESGQPICGNGLVEQGEQCDCGYSDQ-CKDDCCYD--ANQPENLKCTLKPGKQ-----CSPSQGPCCNSGCTFKLRSEKCREESDCAKMGTCNGVSAQCPPSDPRDNLTECNRATQVCIKGQCSGSICEKY-DLEECTCGSSDGKDDKELCHVCCMEKMKPHTCASTGSEAWRAHFK-------------GKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 706

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Match: Adam10 (a disintegrin and metallopeptidase domain 10 [Source:MGI Symbol;Acc:MGI:109548])

HSP 1 Score: 456.062 bits (1172), Expect = 1.507e-146
Identity = 294/780 (37.69%), Postives = 415/780 (53.21%), Query Frame = 1

Query:   46 LETFILLILCIAAS-----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTER------PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            L T ++L+L  AA      G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  + F L +  D ++F    ++  ++K    +      GH++ +  S  +G+++DG F GFI++       G +Y+E +  Y ++    FHS+IYH+       ++NY     P   G  + ++   M    +   +       E+      P+  R+KR+   + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C K   CNG    CP S   P+ T C  +T+VC NGQC GSICE      EC+   S+    + +C V C + M  + C ST  LQ   +              + + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    3 LPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLLLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIKT-----RGGTFYIEPAERYIKDRILPFHSVIYHED------DINYPHKYGPQG-GCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDDCCFD--ANQPEGKKCKLKP----GKQ-----CSPSQGPCCTAQCAFKSKSEKCRDDSDCAKEGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYD-LEECTCASSDGKDDKELCHVCCMKKMAPSTCASTGSLQWSKQF-------------SGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 708

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Match: Adam10 (a disintegrin and metallopeptidase domain 10 [Source:MGI Symbol;Acc:MGI:109548])

HSP 1 Score: 300.442 bits (768), Expect = 1.058e-90
Identity = 204/549 (37.16%), Postives = 294/549 (53.55%), Query Frame = 1

Query:   46 LETFILLILCIAAS-----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTER------PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP-GGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTP 1608
            L T ++L+L  AA      G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  + F L +  D ++F    ++  ++K    +      GH++ +  S  +G+++DG F GFI++       G +Y+E +  Y ++    FHS+IYH+       ++NY     P   G  + ++   M    +   +       E+      P+  R+KR+   + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P G SGG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D CC    +N P    CKL P
Sbjct:    3 LPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLLLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIKT-----RGGTFYIEPAERYIKDRILPFHSVIYHED------DINYPHKYGPQ-GGCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDDCCFD--ANQPEGKKCKLKP 500

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Match: Adam17 (a disintegrin and metallopeptidase domain 17 [Source:MGI Symbol;Acc:MGI:1096335])

HSP 1 Score: 197.208 bits (500), Expect = 1.404e-52
Identity = 180/662 (27.19%), Postives = 286/662 (43.20%), Query Frame = 1

Query:   97 LSSFIKNFDKLNY-NTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIP----VKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSI---FTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRI-NTTDDCDPGQ----IRDSNPFCSANI-DVTNFLNLNSYVKHDD---FCLAYIFTYRDFNGGTLGLAWVAEPGGS--GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK--GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSK-IELRQKYP 2013
            L S + ++D L+  N      R+    S       + F A  ++F L L      F +N  ++V D        +       GH+  +  S+V   I D      I +D      G  Y     + F ND      ++Y    + D     +S L++P  CG+ N++   ++    +    ++  +F  R + + +   + N      C L + +D   +            KY+   E S+      + +     IY+NT++        + G G +++++RI  +  +  PG+    +  S P    +  DV   L   S+   ++    CLA++FTY+DF+ GTLGLA+V  P  +  GGVC K        +N+   LN+G+ +  NYG  +  K + L   HE+GHNFG++HD D     +C P  ED  G Y+M+  A SGD ENN  FS CS+ SI +    +   +  CF  +    CGN   ++GE+CD G    +  D CC     NS C L P          V CS     CC N CQF+  Q  C+      C   +YC G  ++CP      D T C D  + CK G+CI   C+  +    C+ V ++       C V C+    + PC+   D + K + LR+  P
Sbjct:   35 LDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTD------GAEYNVEPLWRFVNDTKDKRMLVYKSEDIKD-----FSRLQSPKVCGYLNADSEELLPKGLIDREPSE--EFVRRVKRRAEPNPLKN-----TCKLLVVADHRFY------------KYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAG----FKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNI--YLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL--AECAP-NEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKT---IESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCC-----NSDCTLKPG---------VQCSDRNSPCCKN-CQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGK-CKAGKCI-PFCKREQELESCACVDTDN-----SCKVCCRN--LSGPCVPYVDAEQKNLFLRKGKP 629

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Match: Adam17 (a disintegrin and metallopeptidase domain 17 [Source:MGI Symbol;Acc:MGI:1096335])

HSP 1 Score: 198.364 bits (503), Expect = 4.963e-52
Identity = 185/696 (26.58%), Postives = 293/696 (42.10%), Query Frame = 1

Query:   97 LSSFIKNFDKLNY-NTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIP----VKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSI---FTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRI-NTTDDCDPGQ----IRDSNPFCSANI-DVTNFLNLNSYVKHDD---FCLAYIFTYRDFNGGTLGLAWVAEPGGS--GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK--GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCR 2118
            L S + ++D L+  N      R+    S       + F A  ++F L L      F +N  ++V D        +       GH+  +  S+V   I D      I +D      G  Y     + F ND      ++Y    + D     +S L++P  CG+ N++   ++    +  ++    +F  R + + +   + N      C L + +D   +            KY+   E S+      + +     IY+NT++        + G G +++++RI  +  +  PG+    +  S P    +  DV   L   S+   ++    CLA++FTY+DF+ GTLGLA+V  P  +  GGVC K        +N+   LN+G+ +  NYG  +  K + L   HE+GHNFG++HD D     +C P  ED  G Y+M+  A SGD ENN  FS CS+ SI +    +   +  CF  +    CGN   ++GE+CD G    +  D CC     NS C L P          V CS     CC N CQF+  Q  C+      C   +YC G  ++CP      D T C D  + CK G+CI   C+  +    C+ V ++       C V C+    + PC+   D +                    K + L+ G PC    G+CD   +C 
Sbjct:   35 LDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTD------GAEYNVEPLWRFVNDTKDKRMLVYKSEDIKD-----FSRLQSPKVCGYLNADSEELLPKGLI--DREPSEEFVRRVKRRAEPNPLKN-----TCKLLVVADHRFY------------KYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAG----FKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNI--YLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL--AECAP-NEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKT---IESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCC-----NSDCTLKPG---------VQCSDRNSPCCKN-CQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGK-CKAGKCI-PFCKREQELESCACVDTDN-----SCKVCCRN--LSGPCVPYVDAE-------------------QKNLFLRKGKPC--TVGFCDMNGKCE 642

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Match: Adam17 (a disintegrin and metallopeptidase domain 17 [Source:MGI Symbol;Acc:MGI:1096335])

HSP 1 Score: 195.667 bits (496), Expect = 3.974e-51
Identity = 186/704 (26.42%), Postives = 295/704 (41.90%), Query Frame = 1

Query:   97 LSSFIKNFDKLNY-NTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIP----VKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMS----------LHHIKGQKYLAIKE-ISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRI-NTTDDCDPGQ----IRDSNPFCSANI-DVTNFLNLNSYVKHDD---FCLAYIFTYRDFNGGTLGLAWVAEPGGS--GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK--GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCR 2118
            L S + ++D L+  N      R+    S       + F A  ++F L L      F +N  ++V D        +       GH+  +  S+V   I D      I +D      G  Y     + F ND      ++Y    + D     +S L++P  CG+ N++   ++    +  ++    +F  R + + +   + N      C L + +D   + K M           L +I G +     +       + +     IY+NT++        + G G +++++RI  +  +  PG+    +  S P    +  DV   L   S+   ++    CLA++FTY+DF+ GTLGLA+V  P  +  GGVC K        +N+   LN+G+ +  NYG  +  K + L   HE+GHNFG++HD D     +C P  ED  G Y+M+  A SGD ENN  FS CS+ SI +    +   +  CF  +    CGN   ++GE+CD G    +  D CC     NS C L P          V CS     CC N CQF+  Q  C+      C   +YC G  ++CP      D T C D  + CK G+CI   C+  +    C+ V ++       C V C+    + PC+   D +                    K + L+ G PC    G+CD   +C 
Sbjct:   35 LDSLLSDYDILSLANIQQHSIRKRDLQSATHLETLLTFSALKRHFKLYLTSSTERFSQNLRVVVVDGKEESEYSVKWQNFFSGHVVGEPDSRVLAHIGDDDVTVRINTD------GAEYNVEPLWRFVNDTKDKRMLVYKSEDIKD-----FSRLQSPKVCGYLNADSEELLPKGLI--DREPSEEFVRRVKRRAEPNPLKN-----TCKLLVVADHRFY-KYMGRGEESTTTNYLGYISGTRDRVTTDCFLEFLIELIDRVDDIYRNTSWDNAG----FKGYGVQIEQIRILKSPQEVKPGERHFNMAKSFPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYNPTVKKNI--YLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL--AECAP-NEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKT---IESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLN-NDTCC-----NSDCTLKPG---------VQCSDRNSPCCKN-CQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGDAEDDTVCLDLGK-CKAGKCI-PFCKREQELESCACVDTDN-----SCKVCCRN--LSGPCVPYVDAE-------------------QKNLFLRKGKPC--TVGFCDMNGKCE 661

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Match: sp|Q10741|ADA10_BOVIN (Disintegrin and metalloproteinase domain-containing protein 10 OS=Bos taurus OX=9913 GN=ADAM10 PE=1 SV=1)

HSP 1 Score: 463.766 bits (1192), Expect = 1.050e-148
Identity = 293/764 (38.35%), Postives = 410/764 (53.66%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPK---------RQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ L+Y+ +     H+R +R+   S + Q L + F A  ++F L +  D ++F +   +  ++     +      GH++ +  S  +G+++DG F GFIQ+       G +YVE +  Y ++    FHS+IYH+            D+K P   G       H +     ++    + + T+ PQ K         R+KR+   + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D+CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C K   CNG    CP S   P+ T C  +T+VC NGQC GSICE   G  EC+   S+    + +C V C + M  + C ST  +Q       KY L         + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+ +WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   22 GNPLNKYIRHYEGLSYDVDSLHQKHQRAKRAV--SHEDQFLRLDFHAHGRHFNLRMKRDTSLFSEEFRVETSNAVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQT-----HGGTFYVEPAERYIKDRTLPFHSVIYHED-----------DIKYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQTPQEKHAINGPELLRKKRTTVAEKN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTADEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDECCYD--ANQPEGKKCKLKP----GKQ-----CSPSQGPCCTAHCAFKSKTEKCRDDSDCAKEGICNGITALCPASDPKPNFTDCNRHTQVCINGQCAGSICEK-HGLEECTCASSDGKDDKELCHVCCMKKMEPSTCASTGSVQ-----WNKYFL--------GRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAYWWAVLLMGIALIMLMAGFIKICSVHTPSSN 707

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Match: sp|O77633|ADA10_PIG (Disintegrin and metalloproteinase domain-containing protein 10 OS=Sus scrofa OX=9823 GN=ADAM10 PE=2 SV=2)

HSP 1 Score: 462.225 bits (1188), Expect = 4.890e-148
Identity = 290/764 (37.96%), Postives = 408/764 (53.40%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPK---------RQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ L+Y+ +     H+R +R+   S + Q L + F A  ++F L +  D ++F     +  ++K    +      GH++ +  S  +G+++DG F GFIQ+       G +Y+E +  Y ++    FHS+IYH+            D+  P   G       H +     ++    + + T+ PQ K         R+KR+ S + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GEQCDCGYS + C+D+CC    +N P    C+L P+           CSPS G CCT  C+F+     CR   +C K   CNG    CP S   P+ T C  +T+VC NGQC GSICE   G  EC+   S+    + +C V C + M    C ST   + K           K  L   + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+ +WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   22 GNPLNKYIRHYEGLSYDVDSLHQKHQRAKRAV--SHEDQFLRLNFHAHGRHFNLRMKRDTSLFSDEFRVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQT-----HGGTFYIEPAERYIKDRTLPFHSVIYHED-----------DINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQTPQEKHANNGPELLRKKRTTSAEKN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTADEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDS----GTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEQCDCGYSDQ-CKDECCYD--ANQPEGKKCRLKPE---------KECSPSQGPCCTAQCKFKSKTEKCRDDSDCAKEGICNGITALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKY-GLEECTCASSDGKDDKELCHVCCMKKMEPLTCASTGSEKWK-----------KHFL--GRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAYWWAVLLMGIALIMLMAGFIKICSVHTPSSN 707

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Match: sp|Q10743|ADA10_RAT (Disintegrin and metalloproteinase domain-containing protein 10 OS=Rattus norvegicus OX=10116 GN=Adam10 PE=1 SV=2)

HSP 1 Score: 461.07 bits (1185), Expect = 1.254e-147
Identity = 297/780 (38.08%), Postives = 416/780 (53.33%), Query Frame = 1

Query:   46 LETFILLILCIAAS-----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTER------PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            L T ++L+L  AA      G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  + F L +  D ++F    ++  ++K    +      GH++ +  S  +G++VDG F GFIQ+       G +Y+E +  Y ++    FHS+IYH+       ++NY     P   G  + ++   M    +   +      +E       P+  R+KR+   + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D+CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C K   CNG    CP S   P+ T C  +T+VC NGQC GSICE      EC+   S+    + +C V C + M  + C ST  LQ   +              N + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    3 LPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLLLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVVDGRFEGFIQT-----RGGTFYIEPAERYIKDRILPFHSVIYHED------DINYPHKYGPQG-GCADHSVFERMRKYQMTGVEEGTRAHSEEHAASMGPELLRKKRTTLAERN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDECCFD--ANQPEGKKCKLKP----GKQ-----CSPSQGPCCTAQCAFKSKSEKCRDDSDCAKEGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYD-LEECTCASSDGKDDKELCHVCCMKKMAPSTCASTGSLQWNKQF-------------NGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 708

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Match: sp|O14672|ADA10_HUMAN (Disintegrin and metalloproteinase domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ADAM10 PE=1 SV=1)

HSP 1 Score: 459.914 bits (1182), Expect = 2.875e-147
Identity = 290/764 (37.96%), Postives = 408/764 (53.40%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPK---------RQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  ++F L +  D ++F    ++  ++K    +      GH++ +  S  +G+++DG F GFIQ+       G +YVE +  Y ++    FHS+IYH+            D+  P   G       H +     ++    + + T+ PQ +         R+KR+ S + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D+CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C +   CNG    CP S   P+ T C  +T+VC NGQC GSICE   G  EC+   S+    + +C V C + M  + C ST  +Q                  + + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   22 GNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQT-----RGGTFYVEPAERYIKDRTLPFHSVIYHED-----------DINYPHKYGPQGGCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTADEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDECCFD--ANQPEGRKCKLKP----GKQ-----CSPSQGPCCTAQCAFKSKSEKCRDDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKY-GLEECTCASSDGKDDKELCHVCCMKKMDPSTCASTGSVQWSRHF-------------SGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 707

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Match: sp|O35598|ADA10_MOUSE (Disintegrin and metalloproteinase domain-containing protein 10 OS=Mus musculus OX=10090 GN=Adam10 PE=1 SV=2)

HSP 1 Score: 456.062 bits (1172), Expect = 1.054e-145
Identity = 294/780 (37.69%), Postives = 415/780 (53.21%), Query Frame = 1

Query:   46 LETFILLILCIAAS-----GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTER------PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT-DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            L T ++L+L  AA      G  L+ +I++++ L+YN +     H+R +R+   S + Q L + F A  + F L +  D ++F    ++  ++K    +      GH++ +  S  +G+++DG F GFI++       G +Y+E +  Y ++    FHS+IYH+       ++NY     P   G  + ++   M    +   +       E+      P+  R+KR+   + N   C L++Q+D   +          G +   I +ISS    HV+    IYQ T+F           I F V R+RINTT D+ DP     +NPF   NI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NYGS+V  KVS +TFAHE+GHNFGS HD       +C P     L +   GNYIM+A ATSGDK NNNKFS+CS  +I+++L    K   NCF+      CGN + E GE+CDCGYS + C+D CC    +N P    CKL P     KQ     CSPS G CCT  C F+     CR   +C K   CNG    CP S   P+ T C  +T+VC NGQC GSICE      EC+   S+    + +C V C + M  + C ST  LQ   +              + + I L+ G+PC+++ GYCD F+RCR V+ADGPLAR+K  IFS  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    3 LPTVLILLLSWAAGLGGQYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAV--SHEDQFLLLDFHAHGRQFNLRMKRDTSLFSDEFKVETSNKVLDYDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIKT-----RGGTFYIEPAERYIKDRILPFHSVIYHED------DINYPHKYGPQG-GCADHSVFERMRKYQMTGVEEGARAHPEKHAASSGPELLRKKRTTLAERN--TCQLYIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDTIYQTTDFSGIRN------ISFMVKRIRINTTSDEKDP-----TNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHD----SGTECTPGESKNLGQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLE---KKRNNCFVESGQPICGNGMVEQGEECDCGYSDQ-CKDDCCFD--ANQPEGKKCKLKP----GKQ-----CSPSQGPCCTAQCAFKSKSEKCRDDSDCAKEGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYD-LEECTCASSDGKDDKELCHVCCMKKMAPSTCASTGSLQWSKQF-------------SGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPQLYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 708

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Match: I1ZIA5 (Disintegrin and metalloproteinase domain containing protein-2 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1169.84 bits (3025), Expect = 0.000e+0
Identity = 598/598 (100.00%), Postives = 598/598 (100.00%), Query Frame = 1

Query:  871 GDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRKRIVPNSANHXXXXXXXXXXXXIEVPPNGITHPSAXXXXXXXXXXXXXKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPLSMNFDSNVELHEVSNIIASHVKPSYPPPAYAEV 2664
            GDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICVGGIIFVGIFLKLFSRSTPSSNPKLRKRIVPNSANHRRSDRPSEPRSRIEVPPNGITHPSAPPPRPNRQSMPPRKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPLSMNFDSNVELHEVSNIIASHVKPSYPPPAYAEV
Sbjct:   49 GDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICVGGIIFVGIFLKLFSRSTPSSNPKLRKRIVPNSANHRRSDRPSEPRSRIEVPPNGITHPSAPPPRPNRQSMPPRKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPLSMNFDSNVELHEVSNIIASHVKPSYPPPAYAEV 646

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Match: A0A5J4P1S2 (Disintegrin and metalloproteinase domain-containing protein 10 OS=Paragonimus westermani OX=34504 GN=DEA37_0010081 PE=4 SV=1)

HSP 1 Score: 801.971 bits (2070), Expect = 0.000e+0
Identity = 418/835 (50.06%), Postives = 528/835 (63.23%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT-----NHKRFRRS-ATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFS-----SQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHL---HDSHNLNYSDL--KNPSFCGWTNSNISHVMH---------LASVQHNKNKI-------------------NDF-----TERPQPKRQKRSVSNKG-NQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTD-DCDP-------------------------------------------------GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHK-ENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSS 2298
            +++++ ++D L+Y        H R RRS  T      P++    AF +N  L L  D  +      ++V  +       + V  H +  ++     S V+G+++ G+FRG I  +   QS G Y+VE +  +F++   FHSIIYHDSH+        +  S +  K  +FCG ++  I+  M          L  V     +                    ND      T  P   R   + S  G N  VCNL+LQSDTFLWD+++S+ HI+G + LA+KEI+SIFTQHVQGAQAIYQ+T F+   G   Y GI FRVD V IN T+ DC                                                   G   D NPFC+ NIDVTN+LNL+SY  H+DFCLAY+FTYRDF+GGTLGLAWVAEP GSGGVCEKHR+M+EG+ NV KSLNTG+VTLLNYGS VALKVSQLTFAHEMGHNFG+KHDDDHK E   CLP ++DP+GNYIMFASATSGDK+NNNKFS+CS DSIARLL R+    GNCFL  +G FCGN+L E+GEQCDCG++   C+D+CC+PK S SPCKLT  I +N+    V CSP+AGECCT+DCQ +   HLCR  GECH++AYCNG   KCP S+ +PD T CQD+TRVCK GQC+GSICE + GWHECS+ R + VTPE+MCFV+C+EN ++APCISTF L+   +L+++YP L  ELL +    +LK GAPCDNY GYCD F RCRSVEA+GPLAR++NL+FS  ML K K WI   WWAV+LIC+  II + IF+KLFS STP S
Sbjct:   26 INTYLSDYDVLDYVAVTHVHEHTRVRRSFVTHEKSTIPISFNIVAFRRNLTLVLRPDFELINPTARLIVGGQDQP-GGLLSVADHAYRGYAVNYPESVVFGSVIRGIFRGTISLEA--QSLGSYFVEPAGNFFDHPTPFHSIIYHDSHVKLPESKARVARSTVFPKPIAFCGLSDPIIAQKMRELTSPASGILDEVSKRSRRASVSEPVEVDSNSYAADLSSNDLFNGYRTSNPFAGRISSTSSTAGANTRVCNLYLQSDTFLWDRVISMQHIRGNRDLAVKEITSIFTQHVQGAQAIYQHTLFRDHAGRSDYPGISFRVDYVLINVTEEDCKQRPTLSGLDGVSLSMTPLPPSPTALPHGNRLTNKSMSQLSRSLSHGLLPRGSYADENPFCAENIDVTNYLNLHSYTPHNDFCLAYVFTYRDFSGGTLGLAWVAEPSGSGGVCEKHRLMREGNNNVYKSLNTGVVTLLNYGSQVALKVSQLTFAHEMGHNFGAKHDDDHKDEPYGCLPPIDDPRGNYIMFASATSGDKDNNNKFSLCSSDSIARLLTRILSDDGNCFLSSDGPFCGNQLTEEGEQCDCGFTPNSCRDQCCHPKESASPCKLTNTIFVNETAIKVQCSPTAGECCTHDCQHRGETHLCRAAGECHRSAYCNGVSAKCPPSENLPDGTPCQDHTRVCKQGQCLGSICERISGWHECSLTRDKNVTPEVMCFVSCRENRSSAPCISTFQLEKNSDLQKQYPQLVAELLRDGHGTKLKPGAPCDNYRGYCDVFHRCRSVEAEGPLARLRNLLFSPQMLEKVKAWITVHWWAVILICLCTIIAMVIFVKLFSVSTPRS 857

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Match: G7Y4H2 (Disintegrin and metalloproteinase domain-containing protein 10 OS=Clonorchis sinensis OX=79923 GN=CLF_100889 PE=4 SV=1)

HSP 1 Score: 797.349 bits (2058), Expect = 0.000e+0
Identity = 413/824 (50.12%), Postives = 522/824 (63.35%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSH-----HLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNP-----SFCGWTNSNISHVMHLASVQHNKNKINDFTERPQ------------------------------------PKRQKRSVSNKG-NQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTD-DCDP------------------------------------GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHK-ENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSS 2298
            L      ++ L+Y T      HKR RR+A        L +      +N  L L+ D  +   +  + V    H        D+I  +G++ +  +S V+G+I+ GVFRG +  DK  + +  +Y+E ++ YF+    FHSI+YH+ H+    N+       P     +FCG +N +I+  M       +   +N    R +                                    P  Q++S    G N  VCNL+LQSDTFLWD+++ + HI+G + LA++EI+SIFTQHVQGAQAIYQ+T F+   G  +Y GI FRVD V IN T+ DC P                                    G   D NPFC+ NIDVTN+LNL+SY  HDDFCLAY+FTYRDF+GGTLGLAWVAEP GSGGVCEKHR+M+EGS NV KSLNTG+VTLLNYGS VALKVSQLTFAHEMGHNFG+KHDDDHK E   CLP V+DP+GNYIMFASATSGDK+NNNKFS+CS DSIARLL RV     NCFL  +G FCGN+L E+GEQCDCG++   C+D+CC+PK S+SPCKL   + +N     V CSP+AGECCT++CQF+   HLCR   EC+++AYCNG   KCP S+ +PD T CQD+TR+CK GQCIGSICE + GWHECS+VR++ VTPEMMCFV+C+EN T APCISTF L+    LR KYP L  ELL + +  +LK GAPCDNY GYCD F RCRSVEA+GPLAR++NL+FS  +L + K WI   WWAV+LICV  II + +F KL + STP S
Sbjct:   28 LGDLFVEYELLSYPTAPLVAQHKRVRRNAKTVSAAVRLPLLTSK--QNLTLVLFPDVDLIGASARLTVGGVDHPKGLSGFADYI-YRGYVDSYPNSIVFGSIIQGVFRGTVSLDKSLRDT--FYIEPAANYFDYKTNFHSIMYHEQHVKFDGNMRRIKRSTPDTATFNFCGLSNPDIARRMAELRSPISGVDVNTIPRRSRRASSPLPLNVEIGASRLHPDFQRGHPSAFTDYRLVNPYTQRQSAPVGGANTRVCNLYLQSDTFLWDRVIGMQHIRGNRELAVQEITSIFTQHVQGAQAIYQHTLFRDHAGRLEYPGISFRVDHVLINVTEEDCKPRPVWRDLHGRPLPSPTALPRRPGQDKPSVSNASVSRGSYADENPFCAENIDVTNYLNLHSYTPHDDFCLAYVFTYRDFSGGTLGLAWVAEPNGSGGVCEKHRLMREGSHNVYKSLNTGVVTLLNYGSQVALKVSQLTFAHEMGHNFGAKHDDDHKSEPFGCLPSVDDPRGNYIMFASATSGDKDNNNKFSLCSLDSIARLLGRVLSDDSNCFLKSDGPFCGNQLTEEGEQCDCGFTKSSCRDQCCHPKESSSPCKLRDTVWVNDSSLQVQCSPTAGECCTHNCQFRGTSHLCRGADECYRSAYCNGVEAKCPTSEHLPDGTPCQDHTRICKQGQCIGSICERIPGWHECSLVRNKNVTPEMMCFVSCRENRTGAPCISTFQLEQDSNLRNKYPQLVNELLRDGRGTKLKPGAPCDNYRGYCDVFHRCRSVEAEGPLARLRNLLFSPQVLEQVKSWITMHWWAVILICVSLIIALIVFAKLCAVSTPPS 846

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Match: A0A4S2LDZ5 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_008269 PE=4 SV=1)

HSP 1 Score: 795.808 bits (2054), Expect = 0.000e+0
Identity = 414/825 (50.18%), Postives = 525/825 (63.64%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSH-----HLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNP-----SFCGWTNSNISHVMHL-------------------------------ASVQH---NKNKINDFTE----RPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTD-DCDP------------------------------------GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQ-DCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSS 2298
            L      ++ L+Y T      HKR RR+A   +    + +      +N  L L+ D  +   +  + V    H        D+I  +G++    SS V+G+I+ GVFRG +  DK  + +  +Y+E ++ YF     FHSI+YH+ H+    N+  +    P     +FCG +N +I+  M                                 AS  H    +   N FT+     P  +RQ   + +  N  VCNL+LQSDTFLW++++ + HI+G + LA++EI+SIFTQHVQGAQAIYQ+T F+   G  +Y GI FRVD V IN T+ DC P                                    G   D NPFC+ NIDVTN+LNL+SY  HDDFCLAY+FTYRDF+GGTLGLAWVAEP GSGGVCEKHR+M+EG  NV KSLNTG+VTLLNYGS VALKVSQLTFAHEMGHNFG+KHDDDHK+    CLP V+DP+GNYIMFASATSGDK+NNNKFS+CS DSIARLL RV     NCFL  +G FCGN+L E+GEQCDCG++   C+D+CC+PK S+SPCKL   I +N     V CSP+AGECCT++CQF+   HLCR   EC+++AYCNG   KCP S+ +PD T CQD+TRVCK GQCIGSICE + GWHECS+VR++ VTPEMMCFV+C+EN + APCISTF L+    LR KYP L  ELL + +  +LK GAPCDNY GYCD F RCRSVEA+GPLAR++NL+FS  +L + K WI+  WWAV+LICV  II + +F KL + STP S
Sbjct:   28 LGDLFIEYELLSYPTAPLVAQHKRVRRNA-KIVSAAAIRLPLLTSKQNLTLVLFPDVDLIGASARLTVGGVDHPKGLSGFADYI-YRGYVDAYPSSLVFGSIIQGVFRGTVSLDKSLRDT--FYIEPAANYFNYKTTFHSIMYHEQHVKFDGNMRRTRRSTPDTATFNFCGLSNPDIARRMAGLRSPISGVDVSTIPRRSRRASALRPLNVELGASRLHPDFQRGHPNAFTDYSLVNPYTQRQSAPI-DGANTRVCNLYLQSDTFLWERVIGMQHIRGNRELAVQEITSIFTQHVQGAQAIYQHTLFRDHAGRLEYPGISFRVDHVLINVTEEDCKPRPIWRDLHGHPLPSPTALPRRPGQDKPSVSNTSVSRGSYADENPFCAENIDVTNYLNLHSYTPHDDFCLAYVFTYRDFSGGTLGLAWVAEPNGSGGVCEKHRLMREGGHNVYKSLNTGVVTLLNYGSQVALKVSQLTFAHEMGHNFGAKHDDDHKDEPFGCLPSVDDPRGNYIMFASATSGDKDNNNKFSLCSLDSIARLLGRVLSDDSNCFLKSDGPFCGNQLTEEGEQCDCGFTKSSCRDQCCHPKESSSPCKLRDAIWVNDSSLQVQCSPTAGECCTHNCQFRGTSHLCRGADECYRSAYCNGVEAKCPTSEHLPDGTPCQDHTRVCKQGQCIGSICERIPGWHECSLVRNKNVTPEMMCFVSCRENRSGAPCISTFQLEQDSHLRDKYPQLVNELLRDGRGTKLKPGAPCDNYRGYCDVFHRCRSVEAEGPLARLRNLLFSPQVLEQVKSWIIMHWWAVILICVSLIIALIVFAKLCAVSTPPS 847

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Match: A0A419PTE0 (Disintegrin and metalloproteinase domain-containing protein 10 (Fragment) OS=Clonorchis sinensis OX=79923 GN=ADAM10 PE=4 SV=1)

HSP 1 Score: 795.038 bits (2052), Expect = 0.000e+0
Identity = 414/825 (50.18%), Postives = 528/825 (64.00%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSH-----HLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNP-----SFCGWTNSNISHVMH-----LASVQHN-----------------------------KNKINDFTE----RPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTD-DCDP------------------------------------GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHK-ENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSS 2298
            L      ++ L+Y T      HKR RR+A  ++    + +      +N  L L+ D  +   +  + V    H        D+I  +G++ +  +S V+G+I+ GVFRG +  D+  + +  +Y+E ++ YF+    FHSI+YH+ H+    N+       P     +FCG +N +I+  M      ++ V  N                             +   + FT+     P  +RQ   V +  N  VCNL+LQSDTFLWD+++ + HI+G + LA++EI+SIFTQHVQGAQAIYQ+T F+   G  +Y GI FRVD V IN T+ DC P                                    G   D NPFC+ NIDVTN+LNL+SY  HDDFCLAY+FTYRDF+GGTLGLAWVAEP GSGGVCEKHR+M+EGS NV KSLNTG+VTLLNYGS VALKVSQLTFAHEMGHNFG+KHDDDHK E   CLP V+DP+GNYIMFASATSGDK+NNNKFS+CS DSIARLL RV     NCFL  +G FCGN+L E+GEQCDCG++   C+D+CC+PK S+SPCKL   I +N     V CSP+AGECCT++CQF+   HLCR   EC+++AYCNG   KCP S+ +PD T CQD+TR+CK GQCIGSICE + GWHECS+VR++ VTPEMMCFV+C+EN T APCISTF L+    LR KYP L  ELL + +  +LK GAPCDNY GYCD F RCRSVEA+GPLAR++NL+FS  +L + K WI   WWAV+LICV  II + +F KL + STP S
Sbjct:   28 LGDLFVEYELLSYPTAPLVAQHKRVRRNA-KTVSAAAVRLPLLTCKQNLTLVLFPDVDLIGASARLTVGGVDHPKGLSGFADYI-YRGYVDSYPNSIVFGSIIQGVFRGTVSLDESLRDT--FYIEPAANYFDYKTNFHSIMYHEQHVKFDGNMRRIKRSTPDTATFNFCGLSNPDIARRMAELRSPISGVDVNTIPRRSRRASSPRPLNVEIGASRLHPDFQRGHPSAFTDYRLVNPYTQRQSAPV-DGANTRVCNLYLQSDTFLWDRVIGMQHIRGNRELAVQEITSIFTQHVQGAQAIYQHTLFRDHAGRLEYPGISFRVDHVLINVTEEDCKPRPVWRDLHGRPLPSPTALPRRPGQDKPSVSNASVSRGSYADENPFCAENIDVTNYLNLHSYTPHDDFCLAYVFTYRDFSGGTLGLAWVAEPNGSGGVCEKHRLMREGSHNVYKSLNTGVVTLLNYGSQVALKVSQLTFAHEMGHNFGAKHDDDHKSEPFGCLPSVDDPRGNYIMFASATSGDKDNNNKFSLCSLDSIARLLGRVLSDDSNCFLKSDGPFCGNQLTEEGEQCDCGFTKSSCRDQCCHPKESSSPCKLRDTIWVNDSSLQVQCSPTAGECCTHNCQFRGTSHLCRGADECYRSAYCNGVEAKCPTSEHLPDGTPCQDHTRICKQGQCIGSICERIPGWHECSLVRNKNVTPEMMCFVSCRENRTGAPCISTFQLEQDSNLRDKYPQLVNELLRDGRGTKLKPGAPCDNYRGYCDVFHRCRSVEAEGPLARLRNLLFSPQVLEQVKSWITMHWWAVILICVSLIIALIVFAKLCAVSTPPS 847

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Match: adam10b (disintegrin and metalloproteinase domain-containing protein 10-like [Source:NCBI gene;Acc:103027184])

HSP 1 Score: 455.677 bits (1171), Expect = 5.319e-146
Identity = 289/760 (38.03%), Postives = 412/760 (54.21%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDP-GFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM---HLASVQHNKNKINDFTERPQPK-----RQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLV-----EDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNP--KMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            G  L+ +I++++ L+Y+T     NH+R +R+   S + + L++ F A  ++F L +  D  +F ++ ++ V+ +  + +      G L ++  S  +G+IVDG F GFI++ +     G +YVE S  Y E+    FHS+IYH+       ++NY     P   G  + ++   M    +++V+    + N  +E+         R+KR    + N   C LF+Q+D   + +  +       +   I +ISS    HV+   AIYQ T+F           I F V R+RINTT+D    +   SNPF  ANI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    +KSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       +C P       +  KGNYIM+A ATSGDK NNNKFSVCS  +I+++L    K  GNCF+      CGN L E GE+CDCGYS + C+D CC    +  N  CKL P  +         CSPS G CCT +C ++     CR + EC     CNG   +CP S+   + T C   T+VC NG C GSICE   G   C+    +      +C V C E    + C ST   +           LA+    N K   L+AG+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   26 GNPLNKYIRHYEGLSYDTGSVHNNHQRAKRAL--SHEDRFLHLQFHAHGRHFNLRMRRDTRLFSEDFKLEVSGEEINYDTSHIYSGELFDEQGSITHGSIVDGKFEGFIKTHR-----GTFYVEPSERYLEDKKVPFHSVIYHED------DINYPHKYGPEG-GCADHSVFERMKKYQVSAVEEPAKETNVVSEKKSSDDSMLLRKKRMTQVEKN--TCQLFIQTDHLFFKRYKT-------REAVIAQISS----HVKAIDAIYQGTDFLGIRN------ISFMVKRIRINTTND----ERDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---RKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS----GPECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSVCSVRNISQVLE---KKRGNCFVESGQPICGNGLVEPGEECDCGYSDQ-CRDLCCYDANQPDNKKCKLKPNKV---------CSPSQGPCCTPECTYKSRNEKCRDESECAHQGMCNGASAQCPTSEPKANFTACHGETQVCLNGGCSGSICEKY-GLEVCTCASVDGKDETELCHVCCMEKANPSTCSSTGSER-----------LAR--FFNKKVTTLQAGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 714

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Match: adam10a (disintegrin and metalloproteinase domain-containing protein 10 [Source:NCBI gene;Acc:103043423])

HSP 1 Score: 444.506 bits (1142), Expect = 1.061e-141
Identity = 281/765 (36.73%), Postives = 405/765 (52.94%), Query Frame = 1

Query:   55 FILLILCIAASGFS--LSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP---LVEDPK--GNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            +++L+L    + F   L+ +I++++ L+Y+T+     H+R +R+   S + + +++ F A  ++F L +  D T+F  + ++ ++ +    +      G L  +  +  +G+IVDG F GFIQS +     G YYVE +  Y +N D  +HS+IYH+  +   H             G  + ++   M  + AS   +  +  D      P   ++  + +  Q  C LF+Q+D   +          G +   I +ISS    HV+   +IYQ+T+FQ          I F V R+RINTT D    +   SNPF  ANI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    +KSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       +C P     +D K  GNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K  G CF+      CGN L E GEQCDCGYS + C+D+CC+        K T K       +   CSPS G CCT  C+F+     CR   EC +   CNG   +CP S    + T C   T+VC NG C GSICE       C+    E      +C + C E      C ST   +                  + K   L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  +      WI+ +WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   21 YLILLLAFTRNIFENRLNKYIRHYEGLSYDTDLLHSHHQRAKRAL--SHEDKYVHLDFHAHGRHFNLRMKRDTTLFASDLKVEISGEETPYDTSHIYTGVLFGEKGTLTHGSIVDGKFEGFIQSHQ-----GTYYVEPTERYLKNQDVPYHSVIYHEGDIDYPHKYGREG-------GCADHSVFDRMKKYQASAVDSPAQGEDEERADGPVILRKRRAAQVEQNTCQLFIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDSIYQSTDFQGIRN------ISFMVKRIRINTTLD----EKDKSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---RKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKTQDKKERGNYIMYARATSGDKFNNNKFSICSIRNISQVLD---KKRGLCFVESGQPICGNGLVEPGEQCDCGYSDQ-CKDECCHHANKPEGTKCTLK-------EEAKCSPSQGPCCTTKCEFKSSDEKCRNVSECAEEGMCNGVSAQCPTSTPKQNFTACHSETQVCINGVCTGSICERFN-LEMCTCAVEEGQDETELCHICCMEKGKPNTCRSTGSAEWSD-------------FFDKKVRTLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYENIAEWIVVYWWAVLLMGIALIMLMAGFIKICSVHTPSSN 718

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Match: adam10a (disintegrin and metalloproteinase domain-containing protein 10 [Source:NCBI gene;Acc:103043423])

HSP 1 Score: 442.195 bits (1136), Expect = 3.188e-141
Identity = 286/772 (37.05%), Postives = 406/772 (52.59%), Query Frame = 1

Query:   46 LETFILLILCIAASGF---SLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSD--LKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTER---PQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP---LVEDPK--GNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            ++ F+LL      +G     L+ +I++++ L+Y+T+     H+R +R+   S + + +++ F A  ++F L +  D T+F  + ++ ++ +    +      G L  +  +  +G+IVDG F GFIQS +     G YYVE +  Y +N D  +HS+IYH+  +   H          +  F        S V   A  Q    +  +  ER   P   R++R+   + N   C LF+Q+D   +          G +   I +ISS    HV+   +IYQ+T+FQ          I F V R+RINTT D    +   SNPF  ANI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    +KSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       +C P     +D K  GNYIM+A ATSGDK NNNKFS+CS  +I+++L+   K  G CF+      CGN L E GEQCDCGYS + C+D+CC+        K T K       +   CSPS G CCT  C+F+     CR   EC +   CNG   +CP S    + T C   T+VC NG C GSICE       C+    E      +C + C E      C ST   +                  + K   L+ G+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  +      WI+ +WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:    9 IKLFLLLYYLTHTTGQFENRLNKYIRHYEGLSYDTDLLHSHHQRAKRAL--SHEDKYVHLDFHAHGRHFNLRMKRDTTLFASDLKVEISGEETPYDTSHIYTGVLFGEKGTLTHGSIVDGKFEGFIQSHQ-----GTYYVEPTERYLKNQDVPYHSVIYHEGDIDYPHKYGREGGCADHSVFDRMKKYQASAVDSPA--QETSRRQGEDEERADGPVILRKRRAAQVEQN--TCQLFIQTDHLFFKYY-------GTREAVIAQISS----HVKAIDSIYQSTDFQGIRN------ISFMVKRIRINTTLD----EKDKSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---RKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS----GNECTPGESKTQDKKERGNYIMYARATSGDKFNNNKFSICSIRNISQVLD---KKRGLCFVESGQPICGNGLVEPGEQCDCGYSDQ-CKDECCHHANKPEGTKCTLK-------EEAKCSPSQGPCCTTKCEFKSSDEKCRNVSECAEEGMCNGVSAQCPTSTPKQNFTACHSETQVCINGVCTGSICERFN-LEMCTCAVEEGQDETELCHICCMEKGKPNTCRSTGSAEWSD-------------FFDKKVRTLQPGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYENIAEWIVVYWWAVLLMGIALIMLMAGFIKICSVHTPSSN 716

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Match: si:ch1073-396h14.1 (si:ch1073-396h14.1 [Source:ZFIN;Acc:ZDB-GENE-070705-6])

HSP 1 Score: 288.886 bits (738), Expect = 1.008e-84
Identity = 228/760 (30.00%), Postives = 348/760 (45.79%), Query Frame = 1

Query:   52 TFILLILCIAASGFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPL-VEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            T+++L    A    ++  FIK ++ L+Y+ +     H+R +R      QKQ L + F+AF + F L L +D   F  + ++   ++S   +      G L ++  S   G+I+DG F G I++      +G +YVE +  Y       HS+IYH+  + DS              G  ++       L S+      I          R KR+V     +  C L L +D F + +  S+  +  Q    +K ++ IF +                F+G D  N   F+V  + + + +D       + +P     I     L+L S     ++CL+Y+ T RDF+G  LGLAW  +    GG+C K+  +Q+G  +   SLNTG++TL N+G Y+ LK  QLT AHE  H+ G+ HD    E  DC  L V   KG ++MF  AT    EN+++FS CS   I+RLL ++ K    CF+  +   CGN++ E GE+CD G++     D CC    S  P    C+L P    NKQ     CSPS G CC++ C+F+     C    EC   + C G    CPK    P++T C   TRVC NG+C  S+C  +    +C      K   +  C + C++      C ST    S + +  K            K + L  G+PC    GYCD F  CR V+ADGP+AR+KN             W+   WW ++L  +G    +   + LF  +  S +
Sbjct:   16 TYLILEELSADDLRNMGKFIKYYETLSYDRDSLLHQHQRVKRHLHP--QKQVLKLDFEAFHRAFHLRLKQDFDGFTDDFKVRSGNESRTGDLSHIYSGVLEDENGSSCQGSILDGQFEGSIKT-----PNGTFYVESADKYTNKHSDHHSVIYHEDDVDDS-----------VLGGGGHAGFCGAARLQSL------IQSLRPEGPVSRSKRTVDQ--TKTTCLLHLHADHFFYQRFGSVAAVVAQVASYLKAVNDIFDK--------------ADFDGIDLVN---FKVKSMSVASEED-------ERDPLQETYIGPEKLLSLYSETNWGNYCLSYLLTNRDFSG-VLGLAWEGKADDWGGICSKNLQLQDGRTS---SLNTGLITLKNFGYYLPLKFIQLTLAHEFAHSLGAPHD----EGLDCGGLEVTKGKGRFLMFPQATDKILENSDRFSPCSLRRISRLL-KIKKD--KCFVVSDQPICGNQILEVGEECDVGHNE---SDPCCYS--SRGPVGHQCRLKP----NKQ-----CSPSQGLCCSSSCEFRNPGLTCEEDSECRTKSECTGFSASCPKPAAKPNMTLCSLGTRVCLNGECSRSLC-LIYDLEQCDCPGENK---KEKCHMCCQQKGNPNTCAST--TSSVLSMHFK-----------GKQVALVPGSPCSKNQGYCDHFQTCRLVDADGPVARLKNSFLHLDEFEDLADWMKAQWWVILLAILGISAVMAGTVCLFGHTLESDD 683

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Match: si:ch1073-396h14.1 (si:ch1073-396h14.1 [Source:ZFIN;Acc:ZDB-GENE-070705-6])

HSP 1 Score: 287.73 bits (735), Expect = 3.062e-84
Identity = 225/745 (30.20%), Postives = 341/745 (45.77%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPL-VEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP----CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            +  FIK ++ L+Y+ +     H+R +R      QKQ L + F+AF + F L L +D   F  + ++   ++S   +      G L ++  S   G+I+DG F G I++      +G +YVE +  Y       HS+IYH+  + DS              G  ++       L S+      I          R KR+V     +  C L L +D F + +  S+  +  Q    +K ++ IF +                F+G D  N   F+V  + + + +D       + +P     I     L+L S     ++CL+Y+ T RDF+G  LGLAW  +    GG+C K+  +Q+G  +   SLNTG++TL N+G Y+ LK  QLT AHE  H+ G+ HD    E  DC  L V   KG ++MF  AT    EN+++FS CS   I+RLL ++ K    CF+  +   CGN++ E GE+CD G++  D    CC    S  P    C+L P    NKQ     CSPS G CC++ C+F+     C    EC   + C G    CPK    P++T C   TRVC NG+C  S+C  +    +C      K   +  C + C++      C ST    S + +  K            K + L  G+PC    GYCD F  CR V+ADGP+AR+KN             W+   WW ++L  +G    +   + LF  +  S +
Sbjct:   41 MGKFIKYYETLSYDRDSLLHQHQRVKRHLHP--QKQVLKLDFEAFHRAFHLRLKQDFDGFTDDFKVRSGNESRTGDLSHIYSGVLEDENGSSCQGSILDGQFEGSIKT-----PNGTFYVESADKYTNKHSDHHSVIYHEDDVDDS-----------VLGGGGHAGFCGAARLQSL------IQSLRPEGPVSRSKRTVDQ--TKTTCLLHLHADHFFYQRFGSVAAVVAQVASYLKAVNDIFDK--------------ADFDGIDLVN---FKVKSMSVASEED-------ERDPLQETYIGPEKLLSLYSETNWGNYCLSYLLTNRDFSG-VLGLAWEGKADDWGGICSKNLQLQDGRTS---SLNTGLITLKNFGYYLPLKFIQLTLAHEFAHSLGAPHD----EGLDCGGLEVTKGKGRFLMFPQATDKILENSDRFSPCSLRRISRLL-KIKKD--KCFVVSDQPICGNQILEVGEECDVGHNESD---PCCYS--SRGPVGHQCRLKP----NKQ-----CSPSQGLCCSSSCEFRNPGLTCEEDSECRTKSECTGFSASCPKPAAKPNMTLCSLGTRVCLNGECSRSLC-LIYDLEQCDCPGENK---KEKCHMCCQQKGNPNTCAST--TSSVLSMHFK-----------GKQVALVPGSPCSKNQGYCDHFQTCRLVDADGPVARLKNSFLHLDEFEDLADWMKAQWWVILLAILGISAVMAGTVCLFGHTLESDD 693

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008805.1 (pep scaffold:Pmarinus_7.0:GL478198:183127:199487:-1 gene:ENSPMAG00000007972.1 transcript:ENSPMAT00000008805.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 259.61 bits (662), Expect = 3.188e-78
Identity = 157/408 (38.48%), Postives = 218/408 (53.43%), Query Frame = 1

Query: 1111 GGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLP-----LVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGN-CFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSP--CKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKL 2310
            G SGG+CE++++    S   +KSLNTGIVT+ NYGS+V LKVS +T  HE+GHNFGS HD + +    C+P       +   GNY+M+  A SGDK NN  FS CS DSI+++L    K   N CF+  +   CGN L E+ E+CDCG+  +DC D CC P  + +   C+L P          V CSPS G CC+++C+      LCR + EC KA  C+G    C  S+   + T C   +++C  G C GSICE + G  EC        +PE  C + C     ++ C  T       E  ++Y         N   + L+ G+PCD   GYCDA  RCR V+A+GPL R+K   F   +     +W+   WW   LI VG ++ + +F+ + S   PSSNP  
Sbjct:    2 GASGGICERNKLF---SDRTRKSLNTGIVTVNNYGSHVPLKVSIITITHEVGHNFGSPHDSEAR----CMPGESQERAQRTAGNYLMYPYAQSGDKPNNMLFSPCSVDSISKVL----KAKRNLCFIESDTPVCGNGLVEEDEECDCGFE-EDCVDLCCFPASAPAGQRCRLRPD---------VECSPSEGPCCSHECKLHAAGKLCRPEAECSKAGVCSGDMVICLASEPKDNHTVCNRGSQICMQGLCSGSICE-LYGLEEC---HCPGESPEAQCHICCSNPGESSSCAGT-----SAERWRRY--------FNGSRVALQPGSPCDGLRGYCDAMRRCRRVDAEGPLVRLKKAFFEGKIYLNVVQWVQAHWWGAALIGVGVVVAMILFIVVCSAHVPSSNPNF 371

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Match: adam17a (ADAM metallopeptidase domain 17a [Source:ZFIN;Acc:ZDB-GENE-030131-2862])

HSP 1 Score: 152.525 bits (384), Expect = 2.317e-38
Identity = 120/368 (32.61%), Postives = 170/368 (46.20%), Query Frame = 1

Query: 1024 KHDDFCLAYIFTYRDFNGGTLGLAWVAEPGG--SGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLC--RTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRC 2115
            +    CLA++FTY+DF  G LGLA+VA P G   GGVC K R+ ++   NV  S NTG+ + +NYG  +  K  +L  AHE+GH+FG+ HD      ++C     D  G YIM+  A SGD+ NN  FS CS  S+ ++L   +  + +C   Q   +CGN   EDGEQCD G         CC        C L    L + +  P          C   C+++  Q LC  R    C +AA+C G    CPK   + D T+C D      +G+C+  +C+       C+ +  +K+ P   C  A K +     C            R+     A  L     P+ L  G PC    G+CD   +C
Sbjct:  331 RASQVCLAHLFTYQDFEDGILGLAYVASPTGKTDGGVCSK-RVQEKNGINV--SYNTGLTSTMNYGKTILTKEVELVVAHELGHSFGAGHD-----TEEC-SAGHDADGKYIMYPIAVSGDQPNNGLFSPCSVRSVGQVL---SHKAASCLTPQRHKYCGNFRVEDGEQCDEGPPLGR-NHSCCTHN-----CTLRENALCSDRNSP----------CCQGCRYKD-QVLCQGRLPALCREAAFCTGDSGVCPKPGNLSDGTECLD------HGRCLSGVCQPF-----CTTLE-QKLEP---CVCAEKNDSCKVCC------------RRPGGGCAPYLAAGGSPLLLPRGKPCSV--GFCDIHGQC 640

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007751.1 (pep scaffold:Pmarinus_7.0:GL480181:8636:20908:-1 gene:ENSPMAG00000007002.1 transcript:ENSPMAT00000007751.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 122.094 bits (305), Expect = 5.410e-31
Identity = 97/307 (31.60%), Postives = 143/307 (46.58%), Query Frame = 1

Query:  220 KNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYF-ENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMH-------LASVQHNKNKINDFT--ERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEP 1110
            + F + +  D ++F  +  + +     H +      G LH +  S  YG++  G F GFI +       G Y+VE S  Y       FHSIIYH        ++ + D K  S  G  N ++   M          + +       + T  E    KR+KR VS   N   C L++Q+D           H+  +KY +++ +++    HVQ    IY+ TNF      D    I F V R+R+NTTD     +   SNPF  ANI V  FL+++S   +DD+CL+Y+FT R F+ G LGLAWVA P
Sbjct:    1 RQFNMRMKRDASIFSDDFFVELPTGERHDDTSHIYAGRLHGESDSFCYGSVQSGRFEGFIST-----RHGTYHVEPSERYAARGSMPFHSIIYHQD------DVEFPD-KVGSHAGCANKSVFDQMQRYQRPEGWVAEEQVSAGARELTKSEAEALKRRKRQVSPSKN--TCLLYIQTD-----------HMFFRKYGSVEAVTAEIANHVQAISQIYRVTNF------DNIRNINFLVKRIRVNTTDH----EKDSSNPFRFANIGVDKFLDMHSEGNYDDYCLSYLFTDRVFDNGVLGLAWVASP 272

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007858.1 (pep scaffold:Pmarinus_7.0:GL476347:375920:389428:1 gene:ENSPMAG00000007065.1 transcript:ENSPMAT00000007858.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.3521 bits (220), Expect = 1.424e-18
Identity = 93/298 (31.21%), Postives = 132/298 (44.30%), Query Frame = 1

Query: 1006 NLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGS-------FCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRT-KGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQC--IGSICESVRG 1869
            NL+S  +HD+   A + T R F    LG+A+V      G VC              ++ + GI TL+  GS V +  S L+  HE+GHN G  HDD    N+ C    E      IM A   S        FS CS D +  L+N  T     C L+   +        CG+K+ + GE+CDCG S ++C +KCC+ +     C+L          +  Y     G CC  DCQF     +CR  +G C    +C+G+   CP    + +   CQ+    C NG C    S CE++ G
Sbjct:  232 NLDSMKRHDN---AQLITARQFQS-ILGMAYV------GTVC-------------LRATSGGINTLV--GSSVLMTASVLS--HELGHNLGMSHDD----NRTCSCAAEH---GCIMGAVMGSPPA---TVFSGCSEDDLEGLVNGAT-----CLLNVPKADEALRPPVCGDKMLDAGEECDCG-SPEECDNKCCDART----CRL------RSGARCAY-----GSCC-KDCQFVGQGEVCRAAQGVCDLPEFCSGSAASCPDDSFLQNGHPCQNAAAYCYNGVCQTYTSQCEAIWG 470

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004524.1 (pep scaffold:Pmarinus_7.0:GL476950:296055:347085:1 gene:ENSPMAG00000004117.1 transcript:ENSPMAT00000004524.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.0409 bits (214), Expect = 6.173e-18
Identity = 81/241 (33.61%), Postives = 99/241 (41.08%), Query Frame = 1

Query: 1246 TFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQE-------GSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAG-EC----CTNDCQFQPVQHLCRT-KGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFV 1929
            T AHEMGHNFG  HD   +    C       +G  IM A +T G    N+KFS CS   I  L + ++KG G C  +         G  CGN   EDGEQCDCG   ++C + CCN                        C+  AG EC    C  DCQ +P    CR     C    YCNG    CP +  + D   C      C NG C+    + V  W   S     K  PE +CF 
Sbjct:  211 TMAHEMGHNFGMNHDTPERR---CHCQANSEQGGCIM-APSTGG----NDKFSSCS---IRDLDSSLSKGGGMCLYNMPDVRDLYGGKRCGNGYVEDGEQCDCG-EIEECDNPCCNAN---------------------NCTLRAGAECAHGMCCQDCQLKPSGTRCRDPTNTCDLPEYCNGGSPHCPPNVYLLDGYPCHGKEAYCYNGMCLTHEQQCVTLWGSGS-----KPAPE-ICFA 412

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Match: EDO41812 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S393])

HSP 1 Score: 399.823 bits (1026), Expect = 3.387e-126
Identity = 279/761 (36.66%), Postives = 380/761 (49.93%), Query Frame = 1

Query:   88 GFSLSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIP---VKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSN-KGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDD-FCLAYIFTYRDFNGGTLGLAWVAEP--GGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNR--VTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKD--CQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTND-CQFQP--VQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLR 2313
            G  LS FIK +D L+YN+      H R RRS   +    P+ + F A  + F L L  D ++F  +  +       + NDF P   V G +     S V+G I+DGVF G I           Y+VEHSS YF+    FHS+IYH   +   +        +     W        M  A ++ + +K       P   R +R+ S     +  C L++Q+D      + + H  +  K  AI ++    T HV+  +AIYQ T+F   +GD   + I F + R  +N + +         NPF +ANI V   L LNS  K ++ +CL+YIFTYRDF+ G LGLAWV +   G SGG+CE  +   +G     K LNTG+VT +NYG  V  KVS++TFAHE GHNFGS HD +      C P   D  GNYIMF  ATSG+K NN KFS CSRD +  +L    +      CF   + + CGN++ E+GE CDCGY        DKCC      +    T K           CSPS G CC  D C   P     LC+ + EC   ++CNG +  CP  +  P  T C+D  ++C NG C GSIC    G+ EC      K      C + C  ++ +  C ST D+     +                   L AG+PCDN++GYCD FL+CR V+ADGPL R++ + FS   +     WI  +WWAV+LI VG IIF+ +F+KL S  TPSSNP L+
Sbjct:    1 GGRLSEFIKEYDTLSYNSQSVEKQHGRHRRSVDPN--SNPIILNFLAHERKFKLRLRRDTSIFADDLVV------ENYNDFDPSKVVAGEVLGHKKSLVHGFILDGVFEGKIHIGDDE-----YHVEHSSKYFKEKQPFHSVIYHTQAVEYPYPYGRGCGLSDKIQEWMQKVQRSAMPDADLEGDHSKF-----EPVLHRYRRAASGIDPTKKTCRLYMQAD-----HLYTEHVAQNSKERAILQM----TDHVRAIKAIYQGTDF---DGDGNADLITFVIQRFLVNGSSEAS----NQDNPFRNANIGVAKLLELNSQQKKNEGYCLSYIFTYRDFDDGVLGLAWVGDTTTGSSGGICENWKSFTDG----HKILNTGVVTFINYGKDVPQKVSEITFAHEAGHNFGSPHDPEI--TSACSP--GDSDGNYIMFPRATSGEKSNNRKFSTCSRDKMYLVLQAKGICDQEKCCFKDSQEAICGNRVVEEGESCDCGYQDDASCTADKCCLGSNVQAKTGCTYK-------NGATCSPSQGLCCNGDTCSPYPGNSTFLCQNETECRNQSFCNGINATCPLGEPKPHHTICEDGRKLCINGTCQGSICMKY-GYKECQCTAEPK-----QCDLCC--DVGDGECKSTSDIAEMTTM------------------TLHAGSPCDNFNGYCDVFLKCRKVDADGPLNRLRKIFFSKEAIMSYIEWIKVYWWAVVLIGVGLIIFMAVFIKLCSVHTPSSNPNLK 686

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Match: EDO30803 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZR7])

HSP 1 Score: 350.517 bits (898), Expect = 1.334e-107
Identity = 265/765 (34.64%), Postives = 372/765 (48.63%), Query Frame = 1

Query:   31 MNNIKLETFILLILCIAASGFSLSSFIKNFDKLNYNTNH--KRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDF-IPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNT-NFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLN--RVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCG-YSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNP 2304
            M N  +   + L L        LS +IK+F+ L+YN  H     RRS  D    +   + F+AF +   + L  +  VF  +  IL  D +    D    V G +  +  S VYGT+ DG F+G IQS+ ++     +YVE S  YF+  P FHS+IY    + +  N     +K P                     ++ K +   +RP     +R+   +     C L L +D  L+ K+       G K  A+ ++    T+H+   Q IY+N  N   ++    Y GI FRV ++ I    D  P + +D N      IDV   LNL S   H D C A++FT RDF+ G LGLAW+ +P   GG+C ++  +  G Q +  S NTG+VTL  Y  +   KVS++TFAHE+GH FGS+HD    E+ DC P  +D  GNY+M++ ATSGD+ NN+ FS CS  +I   +N  R       CF+  +   CGN++ E  EQCDCG  +S   +  CCNP      C+LT          P  CSPS G CC  DC++      CR K +C   A C+G+  +CPKS   PD T C    RVC  G+C  SIC       EC            +C V CKE   +  C  T D   K +L ++   L K            AG+PC N HGYCDAF  CR ++ DGPL R+K   F+   L   K  + + WWA++L  +  I+FV + +   +R TPSSNP
Sbjct:    1 MANSIIALLLFLTLANCEELRRLSDYIKHFEPLDYNPTHFHAIHRRSVLDGSHYE---LSFEAFGRERRIRLRRNTGVFTSDAVILNGDGTPLDIDMNSMVAGEVVGEPGSAVYGTMEDGKFQGKIQSNTES-----FYVEPSERYFDK-PEFHSVIYRSEDVENKGNYADMSMKMPEIL------------------DREKRDSGEDRP-----RRATEQEKKLDSCTLALYAD-HLFTKLC------GGKSRAVFKL----TEHITAVQIIYKNAFNTTNYDLYSPY-GITFRVKKMVIYDEQDV-PDKYKDDN----LAIDV--MLNLLSSDDHSDVCEAFMFTDRDFDNGILGLAWIGKPNFLGGICSRYSKV--GGQYI--SYNTGVVTLKLYRLFTPPKVSEVTFAHELGHGFGSEHD---PEDGDCSPGGKD--GNYVMYSKATSGDRPNNDVFSSCSLKAIRDNINDKRGDPKYSGCFISADTPICGNRIIEGNEQCDCGDENSCKAEGGCCNPPGHPQACRLT---------LPATCSPSQGPCCGRDCRYVGNDISCRNKTDCLDKAMCSGSSVECPKSVYQPDNTVCDKGRRVCSVGECAKSICTKY-ALEECQCTADND-----LCTVCCKEPGRDDTCTPTRD---KTQLPKQVHGLMKS-----------AGSPCANMHGYCDAFAVCRRLDLDGPLKRLKEKFFTVKGL---KELVKEKWWAILLGIIAAIVFVALLVFCCARYTPSSNP 673

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Match: EDO27873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T823])

HSP 1 Score: 164.851 bits (416), Expect = 1.336e-46
Identity = 97/202 (48.02%), Postives = 122/202 (60.40%), Query Frame = 1

Query:  808 FTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDD-FCLAYIFTYRDFNGGTLGLAWVAEP--GGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFS 1404
             T HV+  +AIYQ T+F   +GD   + I F + R  +N + +         NPF +ANI V   L LNS  K ++ +CL+YIFTYRDF+ G LGLAWV +   G SGG+CE  +   +G     K LNTG+VT +NYG  V  KVS++TFAHE GHNFGS HD +      C P   D  GNYIMF  ATSG+K NN KFS
Sbjct:    9 MTDHVRAIKAIYQGTDF---DGDGNADLITFVIQRFLVNGSSEAS----NQDNPFRNANIGVAKLLELNSQQKKNEGYCLSYIFTYRDFDDGVLGLAWVGDTTTGSSGGICENWKSFTDG----HKILNTGVVTFINYGKDVPQKVSEITFAHEAGHNFGSPHDPEI--TSACSP--GDSDGNYIMFPRATSGEKSNNRKFS 195

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Match: EDO45760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS75])

HSP 1 Score: 145.976 bits (367), Expect = 1.152e-38
Identity = 108/350 (30.86%), Postives = 163/350 (46.57%), Query Frame = 1

Query: 1180 LNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQ-EGSFCGNKLAEDGEQCDCGYSSKDCQ-DKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNL---IFSSAMLTKAKRWIMQFW 2214
             NT +V+L N+G+ V  K S LT AHE+GH+FGS+HD D   N  C P  E   G +IM+  A  G K NN  FS CS+   A++ + +      CF+ Q +G+FCGN + E GE+CDCG   +  + D CC+P    S     P+  +  +++   CSP  G CC ++C        CR + EC  A    G    CP+    P  T C D+   C +G C+G +C          + + E    + MC V C+       C+ + +L     L+ K+P                 G+ C++Y GYC+   +C +V+    L R+      + S   +  A  W+   W
Sbjct:    2 FNTAVVSLKNFGARVLRKGSVLTTAHELGHSFGSEHDPD---NTLCRP--EGEPGYFIMYDLAVDGKKPNNFLFSECSK---AQMWSVIFNKGPKCFIAQNQGAFCGNSIVEGGEECDCGAPQRCSEVDVCCHPGNITSG---IPECRVKPEYQ---CSPQKGLCCESNCTLS-AHKTCRKETECSYA----GATAVCPEPIPKPRNTTCGDDGNTCLDGACVGPVCARYF------LDQCECQGQDQMCLVCCRTK--KGTCVPSMELNGL--LKYKFP-----------------GSTCNSYTGYCNQLGQCITVKTGDQLLRLMEAFKRMTSEDTINAALTWLQANW 305

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Match: EDO37129 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SGQ0])

HSP 1 Score: 61.6178 bits (148), Expect = 1.659e-10
Identity = 66/214 (30.84%), Postives = 90/214 (42.06%), Query Frame = 1

Query: 1261 MGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQE-----GSFCGNKLAEDGEQCDCGYSSKDCQ---DKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK-GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQC--IGSICESVRG 1869
            MGHN G  HD+       C    +D     IM   A S       K+S CS DS    + R   G   C  +Q       + CGN   E+GE+CDCG ++++C+   D CCN    ++ CKLT                  G CC   C+  P    CR K  EC     C+G    CP ++ V +   C D    C NG C  + + CE++ G
Sbjct:    1 MGHNLGMSHDESV---VGCTCEDKDVNKGCIMSGVARS---IPATKWSKCSEDSFKEFMER---GLDPCLFNQPLMLFGDAICGNGFKEEGEECDCG-TAEECKRYSDDCCN----STTCKLTAGSECMD-----------GPCCFK-CKLSPAGKECREKVSECDLPEVCDGKSELCPANRYVYNGKSCGDGKGFCFNGVCPTLDNQCETLWG 188

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Match: adam10b (disintegrin and metalloproteinase domain-containing protein 10 [Source:NCBI gene;Acc:101172489])

HSP 1 Score: 456.833 bits (1174), Expect = 1.388e-146
Identity = 288/754 (38.20%), Postives = 400/754 (53.05%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM--HLASVQHN--KNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKE-ISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLV-----EDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNP--KMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSN 2301
            L+ +I++++ L+YNT      H+R +R    S + + L++ F A  ++F L +  D T+F  N ++ V+ +    +      G ++ +  +  +G+IVDG F GFIQS +     G YYVE +  Y E+ D  FHS+IYH+  +H  H             G  +S++   M  + AS      K +++   +   P   ++    +  +  C LF+Q+D   +            KY   +E + +  + HV+   AIYQ T+F           I F V R+RINTT D    +   SNPF  ANI V  FL LNS   HDD+CLAY+FT RDF+ G LGLAWV  P GS GG+CEK ++  +G    KKSLNTGI+T+ NY S+V  KVS +TFAHE+GHNFGS HD       +C P       +  KGNYIM+A ATSGDK NNNKFSVCS  +I+++L    K  GNCF+      CGN + E GE+CDCGYS + C+D+CC    +  N  CKL P            CSPS G CCT +C  +     CR + EC     CNG    CP S+   + T C   T+VC NG C GSICE   G   C+    +      +C V C E M    C ST   +           LA+    N K   L AG+PC+++ GYCD F++CR V+ADGPLAR+K  IF+  +      WI+  WWAV+L+ +  I+ +  F+K+ S  TPSSN
Sbjct:   29 LNKYIRHYEGLSYNTEAVHSKHQRVKRGL--SHEDKFLHLDFHAHGRHFNLRMKRDTTLFSPNLKVEVSGEEVPYDTSHIYTGEIYGEKGTLTHGSIVDGKFEGFIQSYQ-----GTYYVEPAERYLEDKDVPFHSVIYHEDDIHYPHKYGPEG-------GCADSSVFERMKKYQASALEEPPKQELHAEADADGPVLLRKRRMAQAEKNTCQLFIQTDHLFF------------KYYNTREAVIAQISSHVKAIDAIYQGTDFMGIRN------ISFMVKRIRINTTLD----EKDRSNPFRFANIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEKSKLYSDGK---KKSLNTGIITVQNYASHVPPKVSHITFAHEVGHNFGSPHDS----GSECTPGESKSQDKKEKGNYIMYARATSGDKLNNNKFSVCSVRNISQVLE---KKRGNCFVESGQPICGNGMVEPGEECDCGYSDQ-CRDQCCYDANQPDNKKCKLKPGKA---------CSPSQGPCCTAECTHKGRNEKCREESECAHQGMCNGASPSCPTSEPKANFTACHGETQVCLNGGCSGSICEKY-GLEACTCASQDGKDETELCHVCCMEKMNPNTCSSTGSER-----------LAR--FFNKKVTTLPAGSPCNDFKGYCDVFMKCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSN 712

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Match: adam10a (ADAM metallopeptidase domain 10 [Source:NCBI gene;Acc:101155340])

HSP 1 Score: 423.705 bits (1088), Expect = 2.633e-134
Identity = 264/738 (35.77%), Postives = 398/738 (53.93%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNT-----NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM---HLASVQHNKNKIN-------DFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPK-----GNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKV--TPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLI 2232
            L+ +I ++++L+Y+T     +H+R +R+   S     +++ F A  ++F L +  D T+F  +  I  +     L+      G +  + +++++G++VDG F GFI +D      G YYVE +  Y +N +   HS+IYH+       +++Y     P   G  + ++   M    +++V+ +  ++N       + T  P   R+KR+  N+  + VC LF+Q+D           H+  + Y + + + +  + HV    AIY NT+F    G      I F V R+RIN T + +     +SNPF  +NI V  FLNLNS   HDDFCLAY+FT RDF+ G LGLAWV    GS GG+C+K +   +G     +SLNTGI+T+ NYGS++   VS +TFAHE+GHNFGS HD +     +C P   + +     GNYIM+A ATSG K NNNKFS CS  SI  +L+R       CF+    + CGN L E+GE+CDCGYS ++C+D CC    +  +  CK+ P            CSPS G CC+N+C+F+   + CR + +C    +CNG+   CPKSK   D T C   T++C+NG C GSIC   +   +C I  SE +   P  +C V C+E++    C ST       E   KY         N   + +  G+PC+++ GYCD   RCR V+ADGPL R++  IF+  +      W+  +WWA++LI
Sbjct:   23 LNKYISHYEELSYDTEALHQSHQRAKRAL--SPHDMTVHLNFHAHGRHFPLRMKRDTTLFTPDLVIEDSGDQPPLDTSHIYSGEIFGERNTRIHGSVVDGRFEGFINTDL-----GTYYVEPAERYLQNKNTTVHSVIYHED------DIDYPHKYGPEG-GCAHDSVFERMKKHQMSAVEESDKEMNFEKEDEEEDTYGPVILRKKRAAENE--KTVCQLFIQTD-----------HLFLKYYGSREAVLAQISNHVSAINAIYMNTDFMGIKG------ISFMVKRIRINGTKEAND----ESNPFRFSNIGVETFLNLNSEQNHDDFCLAYVFTDRDFDDGVLGLAWVGSTAGSSGGICQKTKKYGDGKY---QSLNTGIITVQNYGSHIPPTVSHITFAHEVGHNFGSHHDSE----MECKPGESNDRNTKKLGNYIMYARATSGSKLNNNKFSQCSLHSINSVLSR---KRNICFVEPGQASCGNGLVENGEECDCGYS-EECKDPCCYSASEEISKRCKIKPG---------TECSPSGGPCCSNECKFKNSSNTCRLESDCALKGFCNGSSALCPKSKAKEDFTTCNSETQICQNGVCTGSICHKYK-LEDC-ICSSEDIMNMPAELCHVCCQESLDPTTCSST-----SSERWAKY--------FNKTVLTMPPGSPCNDFKGYCDVLKRCRVVDADGPLLRLRKSIFNPELYENISDWLGAYWWAILLI 688

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Match: adam10a (ADAM metallopeptidase domain 10 [Source:NCBI gene;Acc:101155340])

HSP 1 Score: 413.305 bits (1061), Expect = 4.706e-131
Identity = 255/701 (36.38%), Postives = 377/701 (53.78%), Query Frame = 1

Query:  193 LNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFEN-DPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVM---HLASVQHNKNKIN-------DFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGS-GGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPK-----GNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCC--NPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKV--TPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLI 2232
            +++ F A  ++F L +  D T+F  +  I  +     L+      G +  + +++++G++VDG F GFI +D      G YYVE +  Y +N +   HS+IYH+       +++Y     P   G  + ++   M    +++V+ +  ++N       + T  P   R+KR+  N+  + VC LF+Q+D           H+  + Y + + + +  + HV    AIY NT+F    G      I F V R+RIN T + +     +SNPF  +NI V  FLNLNS   HDDFCLAY+FT RDF+ G LGLAWV    GS GG+C+K +   +G     +SLNTGI+T+ NYGS++   VS +TFAHE+GHNFGS HD +     +C P   + +     GNYIM+A ATSG K NNNKFS CS  SI  +L+R       CF+    + CGN L E+GE+CDCGYS ++C+D CC    +  +  CK+ P            CSPS G CC+N+C+F+   + CR + +C    +CNG+   CPKSK   D T C   T++C+NG C GSIC   +   +C I  SE +   P  +C V C+E++    C ST       E   KY         N   + +  G+PC+++ GYCD   RCR V+ADGPL R++  IF+  +      W+  +WWA++LI
Sbjct:    3 VHLNFHAHGRHFPLRMKRDTTLFTPDLVIEDSGDQPPLDTSHIYSGEIFGERNTRIHGSVVDGRFEGFINTDL-----GTYYVEPAERYLQNKNTTVHSVIYHED------DIDYPHKYGPEG-GCAHDSVFERMKKHQMSAVEESDKEMNFEKEDEEEDTYGPVILRKKRAAENE--KTVCQLFIQTD-----------HLFLKYYGSREAVLAQISNHVSAINAIYMNTDFMGIKG------ISFMVKRIRINGTKEAND----ESNPFRFSNIGVETFLNLNSEQNHDDFCLAYVFTDRDFDDGVLGLAWVGSTAGSSGGICQKTKKYGDGKY---QSLNTGIITVQNYGSHIPPTVSHITFAHEVGHNFGSHHDSE----MECKPGESNDRNTKKLGNYIMYARATSGSKLNNNKFSQCSLHSINSVLSR---KRNICFVEPGQASCGNGLVENGEECDCGYS-EECKDPCCYSASEEISKRCKIKPG---------TECSPSGGPCCSNECKFKNSSNTCRLESDCALKGFCNGSSALCPKSKAKEDFTTCNSETQICQNGVCTGSICHKYK-LEDC-ICSSEDIMNMPAELCHVCCQESLDPTTCSST-----SSERWAKY--------FNKTVLTMPPGSPCNDFKGYCDVLKRCRVVDADGPLLRLRKSIFNPELYENISDWLGAYWWAILLI 633

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Match: si:ch1073-396h14.1 (disintegrin and metalloproteinase domain-containing protein 10 [Source:NCBI gene;Acc:101159183])

HSP 1 Score: 289.656 bits (740), Expect = 5.293e-85
Identity = 211/719 (29.35%), Postives = 329/719 (45.76%), Query Frame = 1

Query:   97 LSSFIKNFDKLNYNTN-----HKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPL-VEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPV-YCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLI 2232
            +S +IK+++ L+Y+T      H R RR+     +   L++ F AF + F L L  D +VF ++  +   + S  ++      G L  +  S  YG+++ G F G IQ+  +      Y++E       +     SIIY    +     +  SD     FC   + NI   + L  V           E     R +R++    ++  C L L  D   ++K  S+  +  Q    I+ ++ IF +      A ++  N            I FRV  + + T +D       +S+P     I     L+L S     +FCL+Y+ T RD++G  LGLAW  + G  GG+C ++  +  G  +   +LNTG++T+ NYG  +  ++  LT AHE+GH+ GS HD    E  +C  L     KG Y+MF  AT   +EN++KFS CS   I+ +L ++ K   +CF       CGN + EDGE+CD G +  D    CC              + +  Q KP+  CSPS G CC  DCQF+P  HLC  + +C +A++C+G  + C       + T C   TR+C NG C  S+C    G  +C             C + C++      C+S+    +   L   +P         N+ + L  GAPC    GYCD F  CR ++ADGP+AR+KN             W+   WWA++L+
Sbjct:   26 ISPYIKHYEVLSYDTEDLHRKHLRARRATQP--EDGTLHLNFTAFQRTFHLILKRDASVFSEDFSVESGNGSASVDLSHLYSGSLKGERGSACYGSVLQGQFEGTIQTGNRT-----YHIESVHRSTGSPTDRLSIIYRKDDMVLPQRMPPSD----GFCAAQHLNI---LGLRPV-----------EEATVSRPRRTIDE--SKTSCLLHLHVDHLYYNKFKSVEAVVAQVAFYIRAVNDIFDK------ADFEGINL-----------INFRVKSLHVMTEED-------ESDPLNPLYIGPEKLLSLFSENNWGNFCLSYLLTNRDYSG-VLGLAWEGKAGNWGGICSQYTTLHNGPMS---TLNTGLITIQNYGEILPPRLVALTVAHELGHSLGSPHD----EGLNCGDLGSSGGKGRYLMFPQATDEVRENSDKFSPCSIKHISSIL-KLKKD--DCFEVSHQPICGNHIVEDGEECDVGQNDTD---LCCYSAKE--------PVGVQCQLKPLKACSPSQGLCCRPDCQFKPATHLCDEETDCQEASFCSGLSSICSTPAAKENFTVCSQGTRICLNGVCAQSVCVK-HGLQQCGCPGDSM---REKCHLCCQQPDEPGTCVSS----TSPTLSAYFP---------NRSLPLVGGAPCSQNQGYCDKFQVCRLLDADGPIARLKNSFLHLDDFDDMAEWMKAHWWAILLV 654

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Match: adam17b (disintegrin and metalloproteinase domain-containing protein 17 [Source:NCBI gene;Acc:101165277])

HSP 1 Score: 202.986 bits (515), Expect = 1.326e-53
Identity = 172/616 (27.92%), Postives = 282/616 (45.78%), Query Frame = 1

Query:   94 SLSSFIKNFDKLNYNT--NHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILV-----NDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINT-TDDCDPGQ----IRDSNPFCSANIDVTNFLNLNSYVKHD---DFCLAYIFTYRDFNGGTLGLAWVA--EPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCR--TKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECS 1884
            SL S +++FD L +++  +H   RR        + + + F A  +NF L L  ++ +F K+   +V      + +H +N      GH+  + +S+V   I +  F   I +D+       Y +E    +    P    +IY    +      N S L+ P+ CG+ +  ++     A        + D  E     R +R + +   +  C L L +D   +     +H  +G++   +    +   + +     IY+NT++     D++++G G ++ ++ I +      PG+    +R S        DV   L   S    D   + CLA++FTY+DF+ GTLGLA+VA  +P   GG+C K       +Q+    LNTG+ +  NYG  +  K + L   HE+GHNFG++HD D  +  DC P  ED  G Y+M+  A SGD+ NN  FS CS+ SI +   R+   + +CF  +  + CGN   E GE+CD G  +    D CC P      C+L          +   CS     CC N C+F     +C+      C   +YC G  ++CP  +  PD T C DN   C NG+C+   C+++     C+
Sbjct:   39 SLRSILEDFDVLPFSSLQSHSVRRREVQTQTHVEKV-LSFSALHRNFQLYLRTNEELFSKDFSAVVVGEDGREHNHPVNRQTFFTGHVIGEENSRVQAHIDNQEFSAHILTDEAE-----YNIEPLWRFTSTPPDGRVLIYRSEDIR-----NISRLQQPAVCGYVSPALTDGRRAA--------VQDEQEEGSGPRSRRQLHDH-RKNTCPLLLVADYRFF-----MHMGRGEESTTL----NYLIELIDRVDDIYRNTSW-----DEEFSGYGVQIQQIIIESGPTPVAPGKSHFNMRGSPVEGKDVWDVKKLLEQFSVDIADKAFNVCLAHLFTYQDFDEGTLGLAYVAPSKPDIPGGLCSKA-CPSSTNQHGAIYLNTGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPD--DILDCAPR-EDQGGKYVMYPIAVSGDQVNNKLFSNCSKRSIVK---RLRSKATSCFRERNINVCGNSRVEQGEECDPGLINISL-DGCCTPD-----CRLR---------EGAQCSDRNSACCKN-CRFASRGVVCQEPINATCEGHSYCTGDSSECPAPENAPDKTVCLDNGE-CHNGECV-PFCQAILNLQPCA 595

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Match: SMESG000076886.1 (SMESG000076886.1)

HSP 1 Score: 1680.61 bits (4351), Expect = 0.000e+0
Identity = 845/845 (100.00%), Postives = 845/845 (100.00%), Query Frame = 1

Query:   31 MNNIKLETFILLILCIAASGFSLSSFIKNFDKLNYNTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICXXXXXXXXXXLKLFSRSTPSSNPKLRKRIVPNSANHXXXXXXXXXXXXIEVPPNGITHPSAXXXXXXXXXXXXXKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPL 2565
            MNNIKLETFILLILCIAASGFSLSSFIKNFDKLNYNTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICVGGIIFVGIFLKLFSRSTPSSNPKLRKRIVPNSANHRRSDRPSEPRSRIEVPPNGITHPSAPPPRPNRQSMPPRKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPL
Sbjct:    1 MNNIKLETFILLILCIAASGFSLSSFIKNFDKLNYNTNHKRFRRSATDSLQKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKGHLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICVGGIIFVGIFLKLFSRSTPSSNPKLRKRIVPNSANHRRSDRPSEPRSRIEVPPNGITHPSAPPPRPNRQSMPPRKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPL 845

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Match: SMESG000057956.1 (SMESG000057956.1)

HSP 1 Score: 146.362 bits (368), Expect = 7.827e-36
Identity = 151/559 (27.01%), Postives = 239/559 (42.75%), Query Frame = 1

Query:  256 VFYKNTEILVND-KSHHLNDF-----IPVKGHLHNDFSSQVYGTIVDGVFR----GFIQSDKKNQ-----SSGIYYVEHSSYYFENDPGFHSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKINDFTERPQPKRQKRSV---------SNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKYLAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTTDDCDP-GQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPG--GSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLN-YGSYVALKVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTNDCQFQPVQHLCRTK---GECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQC 1839
            +   + ++L ND KS +++ F     +P+ G       SQ Y   V G  +     F+ +DK           I+ VE  S Y +N+  F  I+Y            YSDLK      +T        +++S + N              RQKR+V         +    + +C + L +D          H   G+  +          + +     ++++T+F   + ++K +G GF ++++ ++      P G         +    V   L+    + H D CLA++FT++ F+ GTLGLA++A       GG+C +     + S+ V  S+NT   T  +  G  V    + L  AHE+GHN+G+ HD D     DC P      G Y+M+  +  G + NN  FS CSR SI   +   T+G   CFL    +FCGN   +D E+CD G    +  D CC      S C   P  +         CSP+  ECCTNDCQF+P   +C  K     C   + C+G   +C     + D   C ++ R C +G+C
Sbjct:   62 ILKPSVDLLSNDLKSVNIDRFGRETPVPIDG-------SQFYQGFVSGAEKSSVSAFLGNDKMLSINIILDDDIFQVEPLSRYVQNNSSF--IVYR-----------YSDLKG----NFTRGPKCFAKNISSFETNTTN----------SRQKRNVDAIISLPYINKDSTKKLCTIKLIAD-------YRFHREHGRGEMG--RTQHYLIELIDKINILFKSTDFVD-SKNNKNSGYGFIINQILVHVEPTIGPSGHYNQEVAKQTDAWTVEGLLDSFGDIDHKDSCLAHLFTFQSFSEGTLGLAYMASSKTLSYGGICSERDFRHQNSKLV--SVNTAWSTYRDAVGKRVISMSAYLVTAHELGHNWGADHDPD---TTDCAPNAAR-GGKYVMYTYSVVGYEPNNRLFSPCSRRSIGATI--ATRGE-YCFLSPMNAFCGNSRVDDNEECDVG--KNNSADTCCT-----SDCHFKPGAV---------CSPNNHECCTNDCQFKPYGFVCAAKDPMNPCVNHSICSGKEKECLGPLSI-DGPNCTEHGR-CSSGKC 549

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Match: SMESG000043701.1 (SMESG000043701.1)

HSP 1 Score: 96.2857 bits (238), Expect = 5.047e-20
Identity = 118/444 (26.58%), Postives = 184/444 (41.44%), Query Frame = 1

Query:  892 IGFRVDRVRINTTDDCDPGQIRDSNPF-----CSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGGTLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVAL---KVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQ-EGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSA--GECCT-NDCQFQ--PVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLIFSSAML 2181
            I F +  + I T   C+ G      PF     C+ +     FLN   YV    FCL  +   R      LGLA +               M + +QN +         LLN  +   L   K   +T AHE+GH  G++HD++           ++  G YIM         E    FS CS +S+      ++K + +CF ++   SFCGN + E+ E+CDCG +   C   CCN ++    C L              CS     G CC  N+C+++   +   C  + +C    +CNG +   P + ++P +  C +N+R+CKN  C GSIC S+    E       K T ++ C+ + + +M        FD+   +      P + K    N   I  + G+ C + + YC A   C     D  L  I N I + A++
Sbjct:  215 IKFLIKEMFIITPKVCEKGFGGMIWPFPMAIFCNESAGENEFLNAFEYVIDPSFCLTNVVINRTIAAEVLGLATMNS-------------MCDFTQNYR-------AFLLNLAAREILHDTKSISITVAHEIGHTLGAEHDEETP--------CKNESGQYIMSTEFEDPIPE----FSNCSIESMQ---THMSKYNDSCFSNRIPSSFCGNGILEESEECDCG-NQTIC--PCCNGRL----CLLI---------SSAECSSFGKYGMCCNQNNCKWKSRSLNITCSVETDCSTVKFCNGKYGCLPDTPRLPKVI-CDNNSRLCKNETCQGSIC-SLWKLTEYPSKYVAKQTCKLYCY-SSRMDM-------HFDMSELV-----MPKILKN--FNISLITYRVGSECMDTNKYCGATGNC-----DLLLGTIPNTITTYALI 585

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Match: SMESG000043711.1 (SMESG000043711.1)

HSP 1 Score: 80.8777 bits (198), Expect = 2.975e-15
Identity = 92/340 (27.06%), Postives = 136/340 (40.00%), Query Frame = 1

Query: 1243 LTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENN-NKFSVCSRDSIARLLNRVTKGSGNCFLH-QEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSA--GECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLI---FSSAMLTKAKRWIMQFWWAVMLI 2232
            L  AHE+GH   + HD    E   C     +   NYIM      GD     +KFS CS D +   +     G   CF +     FCGN + E  E+CDCG    DC            PC   P  L  K+ +   CSP      CC    C+++P     +C    +C   ++C  T   C      P    C  NT+VCK   C  SIC S+   +E        +     C + C +N T       F L S  ++ +      K++ L+N  I    G+ C   + +CD+F +C  +E +  L  I  ++   F  A+    + + + F  A+ L 
Sbjct:  320 LILAHEIGHLLNANHD----EATTC---KTNGSFNYIM-----QGDLSTTISKFSNCSIDDMLTYVK--ASGRSYCFFNIMRTEFCGNGILEKNEECDCGERQHDC------------PCCTGPICLFTKKSQ---CSPFGRNSMCCDIKTCKWKPRSDNIICSLNTDCVPRSFC--TVQGCAPDSGAPYKVLCARNTKVCKMDICDDSIC-SLWNLNE----YPSHLVSNTSCLLHCFDNATGL----YFPLMSLSQIPK-----LKDVDLSN--ISYIIGSKCMKANEFCDSFGKCVQLEGELSLVDISLMMNPAFYRALALIFRHYFIVFALALALF 612

[Close]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Match: SMESG000043707.1 (SMESG000043707.1)

HSP 1 Score: 80.4925 bits (197), Expect = 4.377e-15
Identity = 92/339 (27.14%), Postives = 135/339 (39.82%), Query Frame = 1

Query: 1243 LTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGDKENNN-KFSVCSRDSIARLLNRVTKGSGNCFLH-QEGSFCGNKLAEDGEQCDCGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSA--GECC-TNDCQFQPVQH--LCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKNGQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDLQSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEADGPLARIKNLI---FSSAMLTKAKRWIMQFWWAVML 2229
            L  AHE+GH   + HD    E   C     +   NYIM      GD      KFS CS D +   +     G   CF       FCGN + E  E+CDCG    DC            PC   P  L  K+ +   CSP      CC    C+++P     +C    +C   ++C  T   C      P    C  NT+VCK   C  SIC S+   +E        +     C + C +N+T       F L S  ++ +      K++ L+N  I    G+ C   + +CD+F +C  +E +  L  I  ++   F  A+    + + + F  A+ L
Sbjct:  320 LILAHEIGHLLNANHD----EATTC---KTNGSFNYIM-----QGDLSTTIPKFSNCSIDDMLTYVK--ASGRSYCFFSIMRTEFCGNGILEKNEECDCGERQHDC------------PCCTGPICLFTKKSQ---CSPFGRNSMCCDIKTCKWKPRSDNIICSLNTDCVPRSFC--TVQGCAPDSGAPYKVLCARNTKVCKMDICDDSIC-SLWNLNE----YPSHLVSNTSCLLHCFDNVTGL----YFPLMSLSQIPK-----LKDVDLSN--ISYIIGSKCMKANEFCDSFGKCVQLEGELSLVDISLMMNPAFYRALALIFRHYFIVFALALAL 611

The following BLAST results are available for this feature:

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Yeast
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ADAM10	5.987e-148	37.96	ADAM metallopeptidase domain 10 [Source:HGNC Symbo...	[more]
ADAM17	4.880e-49	27.00	ADAM metallopeptidase domain 17 [Source:HGNC Symbo...	[more]
ADAM10	1.935e-37	55.64	ADAM metallopeptidase domain 10 [Source:HGNC Symbo...	[more]
ADAM15	1.645e-19	27.25	ADAM metallopeptidase domain 15 [Source:HGNC Symbo...	[more]
ADAM15	2.230e-19	27.25	ADAM metallopeptidase domain 15 [Source:HGNC Symbo...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
sup-17	5.997e-143	36.78	Disintegrin and metalloproteinase domain-containin...	[more]
adm-4	4.196e-27	24.84	Disintegrin and metalloproteinase domain-containin...	[more]
adm-2	3.489e-11	27.80	ADAM (Disintegrin plus metalloprotease) family [S...	[more]
adm-2	3.555e-11	27.80	ADAM (Disintegrin plus metalloprotease) family [S...	[more]
unc-71	4.893e-7	28.42	Disintegrin and metalloproteinase domain-containin...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
kuz	4.702e-121	41.61	gene:FBgn0259984 transcript:FBtr0100660	[more]
kuz	3.095e-120	41.61	gene:FBgn0259984 transcript:FBtr0342903	[more]
kuz	5.411e-120	41.61	gene:FBgn0259984 transcript:FBtr0301412	[more]
kuz	9.750e-120	41.61	gene:FBgn0259984 transcript:FBtr0080509	[more]
kuz	9.750e-120	41.61	gene:FBgn0259984 transcript:FBtr0080510	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
adam10a	5.774e-142	37.20	ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:...	[more]
adam10a	6.131e-142	37.10	ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:...	[more]
adam10a	7.586e-139	36.84	ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:...	[more]
adam10a	7.038e-138	36.63	ADAM metallopeptidase domain 10a [Source:ZFIN;Acc:...	[more]
adam10b	2.391e-112	36.97	ADAM metallopeptidase domain 10b [Source:ZFIN;Acc:...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dnajc24	1.212e-144	37.58	DnaJ heat shock protein family (Hsp40) member C24 ...	[more]
dnajc24	1.554e-143	37.52	DnaJ heat shock protein family (Hsp40) member C24 ...	[more]
dnajc24	1.857e-143	37.01	DnaJ heat shock protein family (Hsp40) member C24 ...	[more]
dnajc24	8.733e-142	37.28	DnaJ heat shock protein family (Hsp40) member C24 ...	[more]
dnajc24	1.238e-141	37.73	DnaJ heat shock protein family (Hsp40) member C24 ...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Adam10	1.507e-146	37.69	a disintegrin and metallopeptidase domain 10 [Sour...	[more]
Adam10	1.058e-90	37.16	a disintegrin and metallopeptidase domain 10 [Sour...	[more]
Adam17	1.404e-52	27.19	a disintegrin and metallopeptidase domain 17 [Sour...	[more]
Adam17	4.963e-52	26.58	a disintegrin and metallopeptidase domain 17 [Sour...	[more]
Adam17	3.974e-51	26.42	a disintegrin and metallopeptidase domain 17 [Sour...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q10741\|ADA10_BOVIN	1.050e-148	38.35	Disintegrin and metalloproteinase domain-containin...	[more]
sp\|O77633\|ADA10_PIG	4.890e-148	37.96	Disintegrin and metalloproteinase domain-containin...	[more]
sp\|Q10743\|ADA10_RAT	1.254e-147	38.08	Disintegrin and metalloproteinase domain-containin...	[more]
sp\|O14672\|ADA10_HUMAN	2.875e-147	37.96	Disintegrin and metalloproteinase domain-containin...	[more]
sp\|O35598\|ADA10_MOUSE	1.054e-145	37.69	Disintegrin and metalloproteinase domain-containin...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
I1ZIA5	0.000e+0	100.00	Disintegrin and metalloproteinase domain containin...	[more]
A0A5J4P1S2	0.000e+0	50.06	Disintegrin and metalloproteinase domain-containin...	[more]
G7Y4H2	0.000e+0	50.12	Disintegrin and metalloproteinase domain-containin...	[more]
A0A4S2LDZ5	0.000e+0	50.18	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A419PTE0	0.000e+0	50.18	Disintegrin and metalloproteinase domain-containin...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
adam10b	5.319e-146	38.03	disintegrin and metalloproteinase domain-containin...	[more]
adam10a	1.061e-141	36.73	disintegrin and metalloproteinase domain-containin...	[more]
adam10a	3.188e-141	37.05	disintegrin and metalloproteinase domain-containin...	[more]
si:ch1073-396h14.1	1.008e-84	30.00	si:ch1073-396h14.1 [Source:ZFIN;Acc:ZDB-GENE-07070...	[more]
si:ch1073-396h14.1	3.062e-84	30.20	si:ch1073-396h14.1 [Source:ZFIN;Acc:ZDB-GENE-07070...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000008805.1	3.188e-78	38.48	pep scaffold:Pmarinus_7.0:GL478198:183127:199487:-...	[more]
adam17a	2.317e-38	32.61	ADAM metallopeptidase domain 17a [Source:ZFIN;Acc:...	[more]
ENSPMAT00000007751.1	5.410e-31	31.60	pep scaffold:Pmarinus_7.0:GL480181:8636:20908:-1 g...	[more]
ENSPMAT00000007858.1	1.424e-18	31.21	pep scaffold:Pmarinus_7.0:GL476347:375920:389428:1...	[more]
ENSPMAT00000004524.1	6.173e-18	33.61	pep scaffold:Pmarinus_7.0:GL476950:296055:347085:1...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO41812	3.387e-126	36.66	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30803	1.334e-107	34.64	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO27873	1.336e-46	48.02	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45760	1.152e-38	30.86	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37129	1.659e-10	30.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
adam10b	1.388e-146	38.20	disintegrin and metalloproteinase domain-containin...	[more]
adam10a	2.633e-134	35.77	ADAM metallopeptidase domain 10 [Source:NCBI gene;...	[more]
adam10a	4.706e-131	36.38	ADAM metallopeptidase domain 10 [Source:NCBI gene;...	[more]
si:ch1073-396h14.1	5.293e-85	29.35	disintegrin and metalloproteinase domain-containin...	[more]
adam17b	1.326e-53	27.92	disintegrin and metalloproteinase domain-containin...	[more]

BLAST of disintegrin and metalloproteinase domain containing protein-2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000076886.1	0.000e+0	100.00	SMESG000076886.1	[more]
SMESG000057956.1	7.827e-36	27.01	SMESG000057956.1	[more]
SMESG000043701.1	5.047e-20	26.58	SMESG000043701.1	[more]
SMESG000043711.1	2.975e-15	27.06	SMESG000043711.1	[more]
SMESG000043707.1	4.377e-15	27.14	SMESG000043707.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30025465
GenBank	AFJ24759.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025465 ID=SMED30025465|Name=disintegrin and metalloproteinase domain containing protein-2|organism=Schmidtea mediterranea sexual|type=transcript|length=3048bp
AATCTATATAAATCTTATATGATTGAATGAATGAATAATATTAAATTAGA
AACATTTATATTGCTAATTCTGTGTATTGCAGCTTCAGGATTTTCACTCA
GTTCTTTCATTAAAAATTTCGATAAGCTAAATTACAACACTAATCATAAA
CGATTTCGTCGATCAGCTACAGATAGCCTTCAAAAGCAACCATTAAATAT
TTTTTTTCAAGCATTTACGAAGAATTTTTTACTAAATTTATATGAAGACG
ATACAGTATTTTATAAAAATACAGAAATCCTTGTGAACGATAAGTCGCAT
CATTTAAATGATTTTATTCCTGTTAAAGGACACCTTCACAACGATTTCTC
AAGCCAAGTCTATGGAACGATTGTAGATGGTGTATTCAGAGGATTTATAC
AATCTGATAAAAAAAATCAGTCAAGTGGAATTTATTACGTAGAACATTCA
AGTTATTATTTTGAAAATGATCCTGGATTTCATTCAATTATATATCATGA
TTCTCATTTACATGATTCTCACAACTTAAATTATTCAGATTTAAAAAACC
CATCATTCTGCGGATGGACAAACTCAAATATTTCACATGTTATGCATTTA
GCTTCAGTTCAGCATAATAAAAATAAAATAAATGATTTTACAGAGAGACC
TCAACCTAAACGTCAAAAACGAAGCGTGTCGAATAAAGGCAACCAATATG
TCTGTAATTTATTTTTACAATCAGATACATTTCTCTGGGACAAAATTATG
AGTTTGCATCACATAAAAGGTCAAAAATATTTGGCAATTAAAGAAATCAG
CTCGATATTTACTCAACACGTTCAAGGAGCTCAGGCTATTTATCAAAATA
CAAATTTCCAAAAATTTAATGGTGATGATAAATACAATGGAATCGGTTTT
CGGGTCGACAGGGTGAGAATAAACACCACAGATGATTGTGATCCCGGACA
AATTAGAGATAGCAATCCGTTTTGTTCGGCAAACATCGACGTGACGAATT
TCTTGAACCTAAATTCTTACGTCAAACACGATGACTTTTGTTTGGCCTAT
ATTTTTACATATCGAGATTTTAATGGTGGGACATTGGGTTTAGCCTGGGT
AGCAGAACCAGGCGGCTCCGGTGGAGTCTGTGAAAAGCATCGGATGATGC
AGGAAGGCAGTCAAAATGTGAAGAAAAGTCTCAACACTGGCATTGTAACA
TTATTAAATTACGGATCCTATGTGGCGCTTAAAGTATCCCAATTAACATT
TGCTCATGAAATGGGTCATAATTTCGGCAGTAAACATGATGATGATCACA
AAGAAAACCAAGACTGTCTTCCATTAGTTGAAGATCCAAAAGGGAATTAC
ATTATGTTTGCAAGTGCCACTAGTGGTGATAAGGAAAACAATAATAAATT
TTCCGTTTGTTCAAGAGACTCAATAGCGAGATTGCTCAACAGAGTAACAA
AAGGTTCTGGAAATTGTTTCTTACACCAAGAGGGATCATTCTGTGGTAAT
AAATTAGCTGAAGACGGTGAACAATGTGATTGTGGTTATTCATCAAAAGA
CTGCCAGGATAAATGTTGCAATCCCAAAATGTCGAATTCTCCATGCAAAT
TAACACCCAAAATCTTAATCAATAAACAATGGAAACCGGTTTACTGTTCT
CCGAGTGCCGGAGAATGCTGCACAAATGATTGCCAATTTCAACCTGTTCA
GCATTTATGTCGAACTAAAGGCGAATGTCACAAAGCTGCTTATTGTAATG
GAACTCACACTAAGTGTCCAAAATCGAAAAAAGTTCCGGACTTAACAAAG
TGTCAGGACAACACTCGAGTGTGTAAAAACGGTCAGTGTATAGGATCAAT
TTGTGAAAGTGTTCGTGGCTGGCATGAATGTTCAATTGTTCGATCTGAAA
AGGTAACGCCTGAAATGATGTGTTTCGTTGCCTGTAAAGAAAATATGACA
AATGCTCCTTGCATAAGCACTTTTGATTTACAATCGAAAATAGAATTACG
ACAAAAATATCCACTTTTAGCTAAAGAGCTTCTTTTAAATAATAAACCAA
TTCAATTGAAAGCTGGTGCTCCGTGTGATAACTATCACGGTTATTGCGAC
GCGTTTTTACGTTGTCGGTCTGTTGAAGCTGATGGACCATTGGCTAGAAT
AAAAAATCTAATCTTCAGTTCAGCAATGTTAACAAAAGCAAAACGTTGGA
TAATGCAATTCTGGTGGGCTGTTATGCTCATATGTGTTGGAGGGATTATT
TTCGTTGGGATATTTCTGAAATTGTTTTCACGAAGTACTCCATCATCAAA
TCCAAAACTACGCAAACGGATTGTACCCAATTCAGCCAATCATCGACGAT
CTGATCGGCCCAGTGAACCCAGAAGTCGAATTGAAGTCCCACCAAATGGA
ATAACACACCCTAGTGCTCCTCCGCCAAGACCAAACCGGCAATCAATGCC
TCCTAGGAAACACACATCAATTCCAGATCACAATCGATTGCATCGGAATC
GAGATCGACCGATGTCACTATATCAATCCAATCCCAATCATTCTGATGCC
TCAACGAGACCTTTAAGTATGAATTTTGATTCCAATGTCGAATTACATGA
AGTTTCAAATATTATTGCCAGTCACGTCAAACCCAGCTATCCGCCTCCAG
CCTATGCAGAAGTGTCGCCAATAATAATGCCTCGTCAACATGGCCACGGT
CGGGGTAAGAAAGGCCATCGACTTGCCCTTAATCAGCAAGCATCGAGATA
TAAATGAATAATCTCGTATTGTCTATTCCTTATCAAGTCCAGTATCTCAT
GAAAATATTTATTGTTATTACTGATATTATTGTTTAATAAATCCTTCGTT
TTTTAATTAATTATCGAAAGAAATAAAGTTAACGATGATTTTGTTTTACA
CAAGAATGTCAATGTATCTTCGTGTTAATAATGGATAATTTATTCGAATA
CTAAATTGTACACTGATTTTATACAGAATTGTACATTTTTGTTTATTGAA
TATTTTTAATGTGATTTGTACACTTAATTGTCCATTTATTGATTGAAT

protein sequence of SMED30025465-orf-1

>SMED30025465-orf-1 ID=SMED30025465-orf-1|Name=SMED30025465-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=909bp
MNNIKLETFILLILCIAASGFSLSSFIKNFDKLNYNTNHKRFRRSATDSL
QKQPLNIFFQAFTKNFLLNLYEDDTVFYKNTEILVNDKSHHLNDFIPVKG
HLHNDFSSQVYGTIVDGVFRGFIQSDKKNQSSGIYYVEHSSYYFENDPGF
HSIIYHDSHLHDSHNLNYSDLKNPSFCGWTNSNISHVMHLASVQHNKNKI
NDFTERPQPKRQKRSVSNKGNQYVCNLFLQSDTFLWDKIMSLHHIKGQKY
LAIKEISSIFTQHVQGAQAIYQNTNFQKFNGDDKYNGIGFRVDRVRINTT
DDCDPGQIRDSNPFCSANIDVTNFLNLNSYVKHDDFCLAYIFTYRDFNGG
TLGLAWVAEPGGSGGVCEKHRMMQEGSQNVKKSLNTGIVTLLNYGSYVAL
KVSQLTFAHEMGHNFGSKHDDDHKENQDCLPLVEDPKGNYIMFASATSGD
KENNNKFSVCSRDSIARLLNRVTKGSGNCFLHQEGSFCGNKLAEDGEQCD
CGYSSKDCQDKCCNPKMSNSPCKLTPKILINKQWKPVYCSPSAGECCTND
CQFQPVQHLCRTKGECHKAAYCNGTHTKCPKSKKVPDLTKCQDNTRVCKN
GQCIGSICESVRGWHECSIVRSEKVTPEMMCFVACKENMTNAPCISTFDL
QSKIELRQKYPLLAKELLLNNKPIQLKAGAPCDNYHGYCDAFLRCRSVEA
DGPLARIKNLIFSSAMLTKAKRWIMQFWWAVMLICVGGIIFVGIFLKLFS
RSTPSSNPKLRKRIVPNSANHRRSDRPSEPRSRIEVPPNGITHPSAPPPR
PNRQSMPPRKHTSIPDHNRLHRNRDRPMSLYQSNPNHSDASTRPLSMNFD
SNVELHEVSNIIASHVKPSYPPPAYAEVSPIIMPRQHGHGRGKKGHRLAL
NQQASRYK*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036436	Disintegrin_dom_sf
IPR022168	DUF3699
IPR001762	Disintegrin_dom
IPR024079	MetalloPept_cat_dom_sf
IPR001590	Peptidase_M12B

Vocabulary: **molecular function**
Term	Definition
GO:0008237	metallopeptidase activity
GO:0004222	metalloendopeptidase activity
GO:0046872	metal ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis
GO:0006509	membrane protein ectodomain proteolysis
GO:0007219	Notch signaling pathway
GO:0007229	integrin-mediated signaling pathway

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001762	Disintegrin domain	SMART	SM00050	DISIN_2	coord: 494..585 e-value: 2.2E-12 score: 57.2
IPR001762	Disintegrin domain	PFAM	PF00200	Disintegrin	coord: 494..581 e-value: 4.5E-13 score: 49.8
IPR001762	Disintegrin domain	PROSITE	PS50214	DISINTEGRIN_2	coord: 485..587 score: 12.934
None	No IPR available	PFAM	PF13574	Reprolysin_2	coord: 262..469 e-value: 8.4E-30 score: 104.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 810..824
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 887..908
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 768..782
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 757..824
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 791..805
None	No IPR available	PANTHER	PTHR45702	FAMILY NOT NAMED	coord: 12..809
None	No IPR available	SIGNALP_EUK	SignalP-TM	SignalP-TM	coord: 1..20 score: 0.513
None	No IPR available	SUPERFAMILY	SSF55486	Metalloproteases ("zincins"), catalytic domain	coord: 274..481
None	No IPR available	TMHMM	TMhelix		coord: 9..27
None	No IPR available	TMHMM	TMhelix		coord: 727..749
IPR024079	Metallopeptidase, catalytic domain superfamily	GENE3D	G3DSA:3.40.390.10		coord: 219..483 e-value: 7.1E-71 score: 241.1
IPR036436	Disintegrin domain superfamily	GENE3D	G3DSA:4.10.70.10		coord: 485..583 e-value: 2.8E-15 score: 58.4
IPR036436	Disintegrin domain superfamily	SUPERFAMILY	SSF57552	Blood coagulation inhibitor (disintegrin)	coord: 543..584
IPR001590	Peptidase M12B, ADAM/reprolysin	PROSITE	PS50215	ADAM_MEPRO	coord: 339..471 score: 15.037

Main menu

disintegrin and metalloproteinase domain containing protein-2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

blazegraph-runner