DDB1-and CUL4-associated factor 1
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025434 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 2
Homology
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Human
Match: DCAF1 (DDB1 and CUL4 associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30911]) HSP 1 Score: 265.388 bits (677), Expect = 2.771e-72 Identity = 194/705 (27.52%), Postives = 329/705 (46.67%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN---ILSSSTPKPISADS------------------------------------NTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQ---CRVFSVGYK 3996
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I R + +S P +A N + + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG +
Sbjct: 275 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVGRQ 943 HSP 2 Score: 61.2326 bits (147), Expect = 1.442e-8 Identity = 38/150 (25.33%), Postives = 68/150 (45.33%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDD 555
L+++W K+ G + L +++ IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + S L+ A R L ++ ++F KE +F+W+ P+ YST + G + D
Sbjct: 17 LLEQWE-KEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMT-SREPPLNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD 159
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Human
Match: DCAF1 (DDB1 and CUL4 associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30911]) HSP 1 Score: 266.544 bits (680), Expect = 1.325e-71 Identity = 194/703 (27.60%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN---ILSSSTPKPISADS------------------------------------NTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I R + +S P +A N + + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 724 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1390 HSP 2 Score: 100.138 bits (248), Expect = 2.724e-20 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 320 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 502 HSP 3 Score: 62.7734 bits (151), Expect = 6.433e-9 Identity = 42/175 (24.00%), Postives = 77/175 (44.00%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN 630
L+++W K+ G + L +++ IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L
Sbjct: 17 LLEQWE-KEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQ 183
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Human
Match: DCAF1 (DDB1 and CUL4 associated factor 1 [Source:HGNC Symbol;Acc:HGNC:30911]) HSP 1 Score: 266.544 bits (680), Expect = 1.443e-71 Identity = 194/703 (27.60%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN---ILSSSTPKPISADS------------------------------------NTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I R + +S P +A N + + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 723 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1389 HSP 2 Score: 100.138 bits (248), Expect = 2.746e-20 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 319 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 501 HSP 3 Score: 58.151 bits (139), Expect = 1.616e-7 Identity = 42/175 (24.00%), Postives = 77/175 (44.00%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN 630
L+++W K+ G + L +++ IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L
Sbjct: 17 LLEQWE-KEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFM-NLVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQ 182
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Celegans
Match: dcaf-1 (DDB1- and CUL4-associated factor homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:Q21106]) HSP 1 Score: 214.542 bits (545), Expect = 8.290e-56 Identity = 184/705 (26.10%), Postives = 337/705 (47.80%), Query Frame = 1
Query: 2038 HLELQNKLWNLIRCYNAIPKLLKIL--EVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKME------IVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDR-ENLSLYDDVVDEKI-----TFSRL----PQTPKRAIENRFNILSSSTPKPISADSNTSILS--------IFK-PKLYR---------ENLNQTSIMTKSVPQNPGKTIT-------LNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNILNYITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLED---GLFFAGENSGIVFTDVDLAQASVEIGEINGTSNA-SNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDI-VSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE------SNEDVGSYAQCRVFSVG 3990
HLE ++W +R + I L+ ++ ++PL+ D S+R + L+G++R ++ +L KLP L+NLM+E V ++ HA FC A +L++ + G+ K+ D + +++ E ++ TQ+ ++ ELL LI+ HL ++ L+ VA +L+ +A LP DR + S+ ++++ + FS++ P R +E+ +S+ P ++ S+ ++ + +F P L R + L + K P PG++ + LN IV + R QH+ C NP++ CP FSL +H CP + + TN++ I+ R+ D + R+ ++ + N + D F+ E GLF N + + +VD ++ G N +A +N+E +K+G +++ SS+FSR + + L ++R H Y+ +F+ T + + T A V D ET +L T + I N A+FS DD L+ + G LWDVR ++ +H FD L I + G FHP+G +++I S V+D+RT+R+L ++P L ++ FN G+ Y + +++ + + + F+ F++RDYS + T + + L +D + VIE S+ + + Q ++ +G
Sbjct: 723 HLE---RMWTEVRKTDGIMALVNLINCKIPLTEAD--SIRKTATNTLTGLARHPEVRQILAKLPLIAHNGLQNLMREPVCSDKRDIHAAFCKEAVQLLQVIYGR------KIHDQQGKEIQSSEKSHRQWVIENTQVSFNQAELLQLIHDHLLKSKLDSVAAMLKSEAKLP--DRPASRSINTPILNKPLPSSGNNFSKINDTYPTLAPRTLESEIGGISARRPSNAASLSSPAMATRSHSTDDDVFATPTLPRRYTTSGAFPKKLMISPARQKLRPLTPGESSSGYRPIKDLNSIVTDYFRNQHSTCKNPVTTCPPFSLFYQHKCPEL---SYQTNVVRNISLRTLDQELLRPHERVYSQWTNERTIFSRFRNWKTIHDHDESYTKATFSVDDEHLIVGLF----NGEVHWINVD---TGLDEGHTNCHGSALTNIEPSKDGSMMLTSSAFSRPLSALWRLGEA---------LQRVHTYREDSCVKFANTTMQRIVGTCRDKATVYDTETNHVLDTYLSG--IDGLQYEKNYASFSPDDKLIFNDGLLWDVRKK-------NSAIHVFDRLSKITLFGTFHPHGTQIVINSEVYDIRTFRMLHHVPELNRCQVSFNSTGNIMYA-TEVTDVHCPDYDEKIFSSFRTFETRDYSALTTFEGRRPVIDLCASHQDQKMCVIEKVRPQMSDYMIQASTQLKIVEIG 1385 HSP 2 Score: 93.9745 bits (232), Expect = 6.524e-19 Identity = 53/185 (28.65%), Postives = 104/185 (56.22%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYG-MLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
P++ AT +R ++ +L E++ L+ + L ++ ++ E+ D+RLTF+AL+ L LL HR +EF + GI LL +P+ S+A+ + CLY + Y ++++ + Q+S + ++ ++ +L+ +E H S M Q L + + L F++ +GPR + N +A L T++ N++
Sbjct: 315 PLSLATYQRFILQYLAACGEYQDLLLQTFEGNALEILFDYIDLEKSKDVRLTFDALKYLTSLLVHRKFALEFVNK-GGIPALLKVPKTSLASVGVVTCLYYIAYSNDVMEILCQMSDEIVDETVQYVLWCLEHSHESGMASACMFFSQGLFYKAI-LRRFDQYDGPRKLHNYIATL-TLMQNNED 496
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Fly
Match: mahj (gene:FBgn0034641 transcript:FBtr0071658) HSP 1 Score: 336.265 bits (861), Expect = 3.087e-94 Identity = 341/1432 (23.81%), Postives = 578/1432 (40.36%), Query Frame = 1
Query: 97 ILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYI---------TSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLE---------------SLNKLSKDSMR---LNWNIIREN-NFPLDEGSNASVRDMLMSQICGVWNLAT-----------------------PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDY------TYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTW-----------KHPYISDRSNIIKVIYSKAG---------FFEDAYNNFH-DIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRP-LQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSST-------------PKPISADSNTSILSIFKPKLYRENLNQTSI---------MTKSVPQN---PG--------------KTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNIL--NY-ITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN--LENTKNGRL--LMASSSFSRRNNGVL-----TLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE--SNEDVGSYAQCRVFSVGYK 3996
+ ++I KW +QT G++P L LAE E E+ + +DPDP D R P + + Y + L F+ L+ +Y+ SRS E L+ +A R + ++ + +F E + NRI+ W+ P+ Y+T + + D I R I L+ + + RL S++ LS DS L+W N + P N S SQ N++ P T + L++ FL + E++ + + + V+ L+ +L D L +E L+ L LLCH+ +EF G+ LLL +PRPS+A +S +Y L Y + ++++ + + L++ L+I+ CH S++C+ + + + L+ F+ +G R + N +++L + + + + D+ +++ + +K +E N+ L + + P S N PT T+ +H I + + G F D N+ + + +LD+LS+ C+ + + + K T +L +S S + +KS L L C P ++ SL+ T RK + + E+IE+V W + N I LL +++ D +R C L+G++R + + ++ KLP F G L+ LM++ + E+ EH F A L+ + G+T ++ D + K ++ +T+IQ++ Q+L LI+ HL+ GL+ A +L+++ LP+ S + D K S + + +R ++++ P A + + + P N QT I +++S+ + PG K ITLN IV +L QH+ C NP++ CP+F L+ H CP KP+ +L NY +T R + +R RYVH F P + +D + D FT K + G + G VF D G SN N ++ K R L+ +SSF R +L F ++ R D T Y EFS+T + + TQ++ A + D+ TGS + + + + L T NRAT D L+LS G LWDVR S +E +H+FD +SGVFHPN LE+I + VWD+RT+ LLQ +P L F+ Y + F D+ DYS +AT++ + I+ L+V +AV+E S + ++++VG K
Sbjct: 113 LTQIIDKWEQQQTQNGYDPVPTLRSLAEIFEREKDVYRRKDPDPLDSRHPYRADPSCQYGLLLKLLFRKDTFMGKLLNDYLRENYFSRQNVSRSSLE-LNILACRLILEIMPGMETSAVFQTAEG---DGTINRIYSWAEDSIEPLQSYATGLLAEAMEVSDIAINFRDLN-IRLVPKMIKRLHMLLAISKSATSDVNTSMHNLSADSSTAGMLSWVACASNASAPQSPQHNGSGLGASSSQHGDASNMSILFENSRDAFSVSRYYKRMYIPLHPATADTSQMLIMRFLTSLGEYQEFLAMAFENNVMQLIFGYLENLDRRDTCLAYEVLKYLASLLCHKKFALEFISH-GGLELLLKVPRPSLATTGVSIAIYYLAYCEDAMERICSMQRPLISELVRYALWILGRCHDSSKCHATMFFSLSFQFKVILDEFDAQDGLRKLYNVISVLKILDPSHNDSDNDSDFNEDVECASRQMVRHVCVALKRYMEAHFF-------YKYNSFLCQTNAASPAPSSAHYFNQNPTVAAKLTFDQLNDQIRTLQEHTSIRAHWQPVDQLMKLGGITMLLRIIAFSYDWVNSGRSETVRSALDVLSVCCIIPRVYVVLCERLLMLDKTTTSGFCSVLGAAAGEIS-SDAEVIKSALAVLCHCVCSPIIRKDSGTSLIKFGTSSRK-NKANHKYAEELIERV------------------------------------------WESVCSNNGIVVLLSLMQTKGPITDADCIRGMACRALAGLARSDRVRQIVSKLPLFASGQLQTLMRDPILQEKRAEHVIFQKYALELLERVSGKTKP-LNNPLDPSLSNMHKANVIAQTRIQYNKQQLYQLIFEHLESNGLSQTAQMLQREVGLPLQTPTTRSFHQSPFDYKSLPSGSSSLSRNRLRSRMQDVNAAIMGNGDLNRSFGEDSSPAGAGGSNAGDGVSIPNFSSLNTTQTPIKIRRTDRSSVSRSIQKQAMEPGGMSVGLAEDGQLHPKRITLNTIVTEYLTNQHSLCNNPVTTCPQFDLYEPHKCP----DPKPSRLLSSNYNLTSRHARTQAGFNTSRFDRRYVHTHFSPWRSIRSAD-YEDLEFTCCDLAGKYIIVG---TQQGDGRVFNMND--------GVEQFFSNCHNFSVDAIKANRAGDLVITSSFWRTPTSILWSIADDEFKLKLRLPDVT------------YCEFSQTVQDRLLGTQNECATLFDINTGSKVASFTP---TIPNLYTKNRATLCRTDELILSDGVLWDVR-SGKE-------IHKFDKFNQCISGVFHPNCLEIIANTEVWDLRTFHLLQTVPVLDQRNCTFSPM-HVIYGASLGADRDHDMETTTYDTSFNVLDAYDYSSIATIDVKRNINDLSVSANGSLIAVVEDYSGYESKQETYVKIYAVGVK 1446
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Fly
Match: mahj (gene:FBgn0034641 transcript:FBtr0304728) HSP 1 Score: 336.265 bits (861), Expect = 3.087e-94 Identity = 341/1432 (23.81%), Postives = 578/1432 (40.36%), Query Frame = 1
Query: 97 ILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYI---------TSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLE---------------SLNKLSKDSMR---LNWNIIREN-NFPLDEGSNASVRDMLMSQICGVWNLAT-----------------------PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDY------TYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTW-----------KHPYISDRSNIIKVIYSKAG---------FFEDAYNNFH-DIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRP-LQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSST-------------PKPISADSNTSILSIFKPKLYRENLNQTSI---------MTKSVPQN---PG--------------KTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNIL--NY-ITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN--LENTKNGRL--LMASSSFSRRNNGVL-----TLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE--SNEDVGSYAQCRVFSVGYK 3996
+ ++I KW +QT G++P L LAE E E+ + +DPDP D R P + + Y + L F+ L+ +Y+ SRS E L+ +A R + ++ + +F E + NRI+ W+ P+ Y+T + + D I R I L+ + + RL S++ LS DS L+W N + P N S SQ N++ P T + L++ FL + E++ + + + V+ L+ +L D L +E L+ L LLCH+ +EF G+ LLL +PRPS+A +S +Y L Y + ++++ + + L++ L+I+ CH S++C+ + + + L+ F+ +G R + N +++L + + + + D+ +++ + +K +E N+ L + + P S N PT T+ +H I + + G F D N+ + + +LD+LS+ C+ + + + K T +L +S S + +KS L L C P ++ SL+ T RK + + E+IE+V W + N I LL +++ D +R C L+G++R + + ++ KLP F G L+ LM++ + E+ EH F A L+ + G+T ++ D + K ++ +T+IQ++ Q+L LI+ HL+ GL+ A +L+++ LP+ S + D K S + + +R ++++ P A + + + P N QT I +++S+ + PG K ITLN IV +L QH+ C NP++ CP+F L+ H CP KP+ +L NY +T R + +R RYVH F P + +D + D FT K + G + G VF D G SN N ++ K R L+ +SSF R +L F ++ R D T Y EFS+T + + TQ++ A + D+ TGS + + + + L T NRAT D L+LS G LWDVR S +E +H+FD +SGVFHPN LE+I + VWD+RT+ LLQ +P L F+ Y + F D+ DYS +AT++ + I+ L+V +AV+E S + ++++VG K
Sbjct: 113 LTQIIDKWEQQQTQNGYDPVPTLRSLAEIFEREKDVYRRKDPDPLDSRHPYRADPSCQYGLLLKLLFRKDTFMGKLLNDYLRENYFSRQNVSRSSLE-LNILACRLILEIMPGMETSAVFQTAEG---DGTINRIYSWAEDSIEPLQSYATGLLAEAMEVSDIAINFRDLN-IRLVPKMIKRLHMLLAISKSATSDVNTSMHNLSADSSTAGMLSWVACASNASAPQSPQHNGSGLGASSSQHGDASNMSILFENSRDAFSVSRYYKRMYIPLHPATADTSQMLIMRFLTSLGEYQEFLAMAFENNVMQLIFGYLENLDRRDTCLAYEVLKYLASLLCHKKFALEFISH-GGLELLLKVPRPSLATTGVSIAIYYLAYCEDAMERICSMQRPLISELVRYALWILGRCHDSSKCHATMFFSLSFQFKVILDEFDAQDGLRKLYNVISVLKILDPSHNDSDNDSDFNEDVECASRQMVRHVCVALKRYMEAHFF-------YKYNSFLCQTNAASPAPSSAHYFNQNPTVAAKLTFDQLNDQIRTLQEHTSIRAHWQPVDQLMKLGGITMLLRIIAFSYDWVNSGRSETVRSALDVLSVCCIIPRVYVVLCERLLMLDKTTTSGFCSVLGAAAGEIS-SDAEVIKSALAVLCHCVCSPIIRKDSGTSLIKFGTSSRK-NKANHKYAEELIERV------------------------------------------WESVCSNNGIVVLLSLMQTKGPITDADCIRGMACRALAGLARSDRVRQIVSKLPLFASGQLQTLMRDPILQEKRAEHVIFQKYALELLERVSGKTKP-LNNPLDPSLSNMHKANVIAQTRIQYNKQQLYQLIFEHLESNGLSQTAQMLQREVGLPLQTPTTRSFHQSPFDYKSLPSGSSSLSRNRLRSRMQDVNAAIMGNGDLNRSFGEDSSPAGAGGSNAGDGVSIPNFSSLNTTQTPIKIRRTDRSSVSRSIQKQAMEPGGMSVGLAEDGQLHPKRITLNTIVTEYLTNQHSLCNNPVTTCPQFDLYEPHKCP----DPKPSRLLSSNYNLTSRHARTQAGFNTSRFDRRYVHTHFSPWRSIRSAD-YEDLEFTCCDLAGKYIIVG---TQQGDGRVFNMND--------GVEQFFSNCHNFSVDAIKANRAGDLVITSSFWRTPTSILWSIADDEFKLKLRLPDVT------------YCEFSQTVQDRLLGTQNECATLFDINTGSKVASFTP---TIPNLYTKNRATLCRTDELILSDGVLWDVR-SGKE-------IHKFDKFNQCISGVFHPNCLEIIANTEVWDLRTFHLLQTVPVLDQRNCTFSPM-HVIYGASLGADRDHDMETTTYDTSFNVLDAYDYSSIATIDVKRNINDLSVSANGSLIAVVEDYSGYESKQETYVKIYAVGVK 1446
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Zebrafish
Match: CABZ01113599.1 (pep scaffold:GRCz11:KN150679.1:255:12836:1 gene:ENSDARG00000108136.2 transcript:ENSDART00000178069.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CABZ01113599.1) HSP 1 Score: 104.375 bits (259), Expect = 6.638e-24 Identity = 55/155 (35.48%), Postives = 82/155 (52.90%), Query Frame = 1
Query: 3544 LWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVGYK 3996
+WDVR S +H+FD +SGVFHPN LEVII + +WD+RT+ LL +P L RI+FN G Y D ++ + + F+ FD+ DY +AT++ + I L D KD +AVIE+ + + CR++ VG +
Sbjct: 1 MWDVRSSQA--------IHKFDKYNMNISGVFHPNSLEVIINTEIWDLRTFHLLHTVPALDQCRIVFNNNGTVIYGAMLQADDEDDMMEQQMKSPFGSSFRTFDATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQDSINMDTVCRLYEVGRQ 147
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Match: nox4 (NADPH oxidase 4 [Source:Xenbase;Acc:XB-GENE-1012418]) HSP 1 Score: 268.855 bits (686), Expect = 1.285e-72 Identity = 188/695 (27.05%), Postives = 325/695 (46.76%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLY-------DDVVDEKITFSRLPQTPKRAIENRF-----------------NILSSSTP--------KPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ ++ LMKE + ++ EH FC A LI + G+ GS++ +L+K ++V +++I + +ELL LI +HL GL + L ++A+LP+ + S Y ++ R P+ P R +S+ +P + + N + + K +Q+ K + ++ TL+ I+ +LR QHA+C NP++ICP FSL H CP + PTN + +T+R+ + + R+ + F+P + E+ ++ +G C A + G +G VF+ + A + I I ++LE +++G LL+ ++++S+ + + ++ +V +H + Y EFSK + + I T++ +A + D++TG L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPN LEVI+ + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 557 SKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSSQIQQLMKEPILQDKRSEHVRFCKYAAELIERVSGKPLLMGSDVSLA------RLQKADVVAQSRITFPEKELLLLIRNHLVSKGLQETVATLTREADLPMTAALHSSTYLPATATQPPTTSSPVSLPRTPRIPARLSSTALCPHPPSRPQLPPPLSSPAPVSTGSPLIGRISFARERQSPCNGKRGRVLRQKSDHGAYSQSPAFRKQMERHVPSPPTLDSIMTEYLREQHARCKNPVAICPPFSLFTPHQCPEPKQRRQAPTNCTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRET----NEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHISAI------THLEPSRDGSLLLTAATWSQPLSALWSMKSV---------FEMKHSFTEDHYVEFSKLSQDRVIGTKEDVAHIYDIQTGQKLLTLYNSDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNALEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNNTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGTMDALNMDTVCRLYEVG 1216 HSP 2 Score: 80.8777 bits (198), Expect = 1.531e-14 Identity = 49/163 (30.06%), Postives = 82/163 (50.31%), Query Frame = 1
Query: 829 ETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
+ L+P LM ++ +R +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V + L+ ++ L+++E H S C+ + L +F+ +G R ++N ++ L + E+Q
Sbjct: 170 QMLLPIFMQMRSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFAAEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHKVLKDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDSQDGLRRLVNLISTLEILNLEDQG 331 HSP 3 Score: 62.003 bits (149), Expect = 9.650e-9 Identity = 37/156 (23.72%), Postives = 70/156 (44.87%), Query Frame = 1
Query: 88 ESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDD 555
+S + ++++W + G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ Y+T + G + D
Sbjct: 11 KSELTTMLEQWESGHG-SGHDMVPVLTRMSELIEKETEEYRKGDPDPFDDRHPGRANPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREAEQPLRTYATGLLGGAMENQD 159
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Match: nox4 (NADPH oxidase 4 [Source:Xenbase;Acc:XB-GENE-1012418]) HSP 1 Score: 269.24 bits (687), Expect = 1.470e-72 Identity = 188/695 (27.05%), Postives = 325/695 (46.76%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLY-------DDVVDEKITFSRLPQTPKRAIENRF-----------------NILSSSTP--------KPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ ++ LMKE + ++ EH FC A LI + G+ GS++ +L+K ++V +++I + +ELL LI +HL GL + L ++A+LP+ + S Y ++ R P+ P R +S+ +P + + N + + K +Q+ K + ++ TL+ I+ +LR QHA+C NP++ICP FSL H CP + PTN + +T+R+ + + R+ + F+P + E+ ++ +G C A + G +G VF+ + A + I I ++LE +++G LL+ ++++S+ + + ++ +V +H + Y EFSK + + I T++ +A + D++TG L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPN LEVI+ + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 693 SKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSSQIQQLMKEPILQDKRSEHVRFCKYAAELIERVSGKPLLMGSDVSLA------RLQKADVVAQSRITFPEKELLLLIRNHLVSKGLQETVATLTREADLPMTAALHSSTYLPATATQPPTTSSPVSLPRTPRIPARLSSTALCPHPPSRPQLPPPLSSPAPVSTGSPLIGRISFARERQSPCNGKRGRVLRQKSDHGAYSQSPAFRKQMERHVPSPPTLDSIMTEYLREQHARCKNPVAICPPFSLFTPHQCPEPKQRRQAPTNCTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRET----NEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHISAI------THLEPSRDGSLLLTAATWSQPLSALWSMKSV---------FEMKHSFTEDHYVEFSKLSQDRVIGTKEDVAHIYDIQTGQKLLTLYNSDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNALEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNNTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGTMDALNMDTVCRLYEVG 1352 HSP 2 Score: 95.9005 bits (237), Expect = 3.938e-19 Identity = 57/194 (29.38%), Postives = 99/194 (51.03%), Query Frame = 1
Query: 751 WNLAT-----PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
W + T P+ A ++RL++ +L + E++ L+P LM ++ +R +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V + L+ ++ L+++E H S C+ + L +F+ +G R ++N ++ L + E+Q
Sbjct: 275 WVIGTNYSLCPLTPAIEQRLILQYLTPLGEYQELLPIFMQMRSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFAAEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHKVLKDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDSQDGLRRLVNLISTLEILNLEDQG 467 HSP 3 Score: 64.3142 bits (155), Expect = 2.051e-9 Identity = 45/180 (25.00%), Postives = 77/180 (42.78%), Query Frame = 1
Query: 172 LAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQR--KSTYINLISQTMTRLESLNKLSKDSMRLN--WNIIRENNFPLDE 699
++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ Y+T + G + D R S + L+ + L+S + K M+ + E PLDE
Sbjct: 18 MSELIEKETEEYRKGDPDPFDDRHPGRANPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREAEQPLRTYATGLLGGAMENQDIAANYRDENSQMVALVLSRLRELQSQDASCKQEMKRQSPRRPLSEPLLPLDE 191
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Match: nox4 (NADPH oxidase 4 [Source:Xenbase;Acc:XB-GENE-1012418]) HSP 1 Score: 269.24 bits (687), Expect = 1.504e-72 Identity = 188/695 (27.05%), Postives = 325/695 (46.76%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLY-------DDVVDEKITFSRLPQTPKRAIENRF-----------------NILSSSTP--------KPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ ++ LMKE + ++ EH FC A LI + G+ GS++ +L+K ++V +++I + +ELL LI +HL GL + L ++A+LP+ + S Y ++ R P+ P R +S+ +P + + N + + K +Q+ K + ++ TL+ I+ +LR QHA+C NP++ICP FSL H CP + PTN + +T+R+ + + R+ + F+P + E+ ++ +G C A + G +G VF+ + A + I I ++LE +++G LL+ ++++S+ + + ++ +V +H + Y EFSK + + I T++ +A + D++TG L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPN LEVI+ + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 713 SKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSSQIQQLMKEPILQDKRSEHVRFCKYAAELIERVSGKPLLMGSDVSLA------RLQKADVVAQSRITFPEKELLLLIRNHLVSKGLQETVATLTREADLPMTAALHSSTYLPATATQPPTTSSPVSLPRTPRIPARLSSTALCPHPPSRPQLPPPLSSPAPVSTGSPLIGRISFARERQSPCNGKRGRVLRQKSDHGAYSQSPAFRKQMERHVPSPPTLDSIMTEYLREQHARCKNPVAICPPFSLFTPHQCPEPKQRRQAPTNCTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRET----NEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHISAI------THLEPSRDGSLLLTAATWSQPLSALWSMKSV---------FEMKHSFTEDHYVEFSKLSQDRVIGTKEDVAHIYDIQTGQKLLTLYNSDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNALEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNNTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGTMDALNMDTVCRLYEVG 1372 HSP 2 Score: 95.9005 bits (237), Expect = 3.780e-19 Identity = 57/194 (29.38%), Postives = 99/194 (51.03%), Query Frame = 1
Query: 751 WNLAT-----PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
W + T P+ A ++RL++ +L + E++ L+P LM ++ +R +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V + L+ ++ L+++E H S C+ + L +F+ +G R ++N ++ L + E+Q
Sbjct: 295 WVIGTNYSLCPLTPAIEQRLILQYLTPLGEYQELLPIFMQMRSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFAAEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHKVLKDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDSQDGLRRLVNLISTLEILNLEDQG 487 HSP 3 Score: 66.2402 bits (160), Expect = 4.400e-10 Identity = 49/208 (23.56%), Postives = 89/208 (42.79%), Query Frame = 1
Query: 88 ESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQR--KSTYINLISQTMTRLESLNKLSKDSMRLN--WNIIRENNFPLDE 699
+S + ++++W + G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ Y+T + G + D R S + L+ + L+S + K M+ + E PLDE
Sbjct: 11 KSELTTMLEQWESGHG-SGHDMVPVLTRMSELIEKETEEYRKGDPDPFDDRHPGRANPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREAEQPLRTYATGLLGGAMENQDIAANYRDENSQMVALVLSRLRELQSQDASCKQEMKRQSPRRPLSEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Match: nox4 (NADPH oxidase 4 [Source:Xenbase;Acc:XB-GENE-1012418]) HSP 1 Score: 269.24 bits (687), Expect = 1.624e-72 Identity = 188/695 (27.05%), Postives = 325/695 (46.76%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLY-------DDVVDEKITFSRLPQTPKRAIENRF-----------------NILSSSTP--------KPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ ++ LMKE + ++ EH FC A LI + G+ GS++ +L+K ++V +++I + +ELL LI +HL GL + L ++A+LP+ + S Y ++ R P+ P R +S+ +P + + N + + K +Q+ K + ++ TL+ I+ +LR QHA+C NP++ICP FSL H CP + PTN + +T+R+ + + R+ + F+P + E+ ++ +G C A + G +G VF+ + A + I I ++LE +++G LL+ ++++S+ + + ++ +V +H + Y EFSK + + I T++ +A + D++TG L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPN LEVI+ + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 701 SKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSSQIQQLMKEPILQDKRSEHVRFCKYAAELIERVSGKPLLMGSDVSLA------RLQKADVVAQSRITFPEKELLLLIRNHLVSKGLQETVATLTREADLPMTAALHSSTYLPATATQPPTTSSPVSLPRTPRIPARLSSTALCPHPPSRPQLPPPLSSPAPVSTGSPLIGRISFARERQSPCNGKRGRVLRQKSDHGAYSQSPAFRKQMERHVPSPPTLDSIMTEYLREQHARCKNPVAICPPFSLFTPHQCPEPKQRRQAPTNCTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRET----NEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHISAI------THLEPSRDGSLLLTAATWSQPLSALWSMKSV---------FEMKHSFTEDHYVEFSKLSQDRVIGTKEDVAHIYDIQTGQKLLTLYNSDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNALEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNNTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGTMDALNMDTVCRLYEVG 1360 HSP 2 Score: 96.2857 bits (238), Expect = 3.566e-19 Identity = 57/194 (29.38%), Postives = 99/194 (51.03%), Query Frame = 1
Query: 751 WNLAT-----PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
W + T P+ A ++RL++ +L + E++ L+P LM ++ +R +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V + L+ ++ L+++E H S C+ + L +F+ +G R ++N ++ L + E+Q
Sbjct: 283 WVIGTNYSLCPLTPAIEQRLILQYLTPLGEYQELLPIFMQMRSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFAAEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHKVLKDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDSQDGLRRLVNLISTLEILNLEDQG 475 HSP 3 Score: 63.929 bits (154), Expect = 2.106e-9 Identity = 45/180 (25.00%), Postives = 77/180 (42.78%), Query Frame = 1
Query: 172 LAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQR--KSTYINLISQTMTRLESLNKLSKDSMRLN--WNIIRENNFPLDE 699
++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ Y+T + G + D R S + L+ + L+S + K M+ + E PLDE
Sbjct: 26 MSELIEKETEEYRKGDPDPFDDRHPGRANPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREAEQPLRTYATGLLGGAMENQDIAANYRDENSQMVALVLSRLRELQSQDASCKQEMKRQSPRRPLSEPLLPLDE 199
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Match: nox4 (NADPH oxidase 4 [Source:Xenbase;Acc:XB-GENE-1012418]) HSP 1 Score: 268.855 bits (686), Expect = 1.872e-72 Identity = 188/695 (27.05%), Postives = 325/695 (46.76%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLY-------DDVVDEKITFSRLPQTPKRAIENRF-----------------NILSSSTP--------KPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ ++ LMKE + ++ EH FC A LI + G+ GS++ +L+K ++V +++I + +ELL LI +HL GL + L ++A+LP+ + S Y ++ R P+ P R +S+ +P + + N + + K +Q+ K + ++ TL+ I+ +LR QHA+C NP++ICP FSL H CP + PTN + +T+R+ + + R+ + F+P + E+ ++ +G C A + G +G VF+ + A + I I ++LE +++G LL+ ++++S+ + + ++ +V +H + Y EFSK + + I T++ +A + D++TG L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPN LEVI+ + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 675 SKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSSQIQQLMKEPILQDKRSEHVRFCKYAAELIERVSGKPLLMGSDVSLA------RLQKADVVAQSRITFPEKELLLLIRNHLVSKGLQETVATLTREADLPMTAALHSSTYLPATATQPPTTSSPVSLPRTPRIPARLSSTALCPHPPSRPQLPPPLSSPAPVSTGSPLIGRISFARERQSPCNGKRGRVLRQKSDHGAYSQSPAFRKQMERHVPSPPTLDSIMTEYLREQHARCKNPVAICPPFSLFTPHQCPEPKQRRQAPTNCTSRLTRRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRET----NEDESGFTCCAFSARERFLMLGTCTGQLKLYNVFSGQEEASYNCHISAI------THLEPSRDGSLLLTAATWSQPLSALWSMKSV---------FEMKHSFTEDHYVEFSKLSQDRVIGTKEDVAHIYDIQTGQKLLTLYNSDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNALEVIVNTEIWDLRTFHLLHTVPALDQCRVVFNNTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGTMDALNMDTVCRLYEVG 1334 HSP 2 Score: 96.2857 bits (238), Expect = 3.296e-19 Identity = 57/194 (29.38%), Postives = 99/194 (51.03%), Query Frame = 1
Query: 751 WNLAT-----PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
W + T P+ A ++RL++ +L + E++ L+P LM ++ +R +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V + L+ ++ L+++E H S C+ + L +F+ +G R ++N ++ L + E+Q
Sbjct: 257 WVIGTNYSLCPLTPAIEQRLILQYLTPLGEYQELLPIFMQMRSRELMMYYIDLKRTNDVLLTFEALKHLASLLLHNKFAAEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHKVLKDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDSQDGLRRLVNLISTLEILNLEDQG 449
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Mouse
Match: Dcaf1 (DDB1 and CUL4 associated factor 1 [Source:MGI Symbol;Acc:MGI:2445220]) HSP 1 Score: 265.774 bits (678), Expect = 1.375e-71 Identity = 195/703 (27.74%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN--------------------ILSSSTPKPISADSNTSIL-------------------SIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I +R S P P + + S L + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 723 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTREADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIASRLGSHATVGASAPSAPPAHPPPRPPQGSLPLPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1389 HSP 2 Score: 99.7525 bits (247), Expect = 2.141e-20 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 319 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 501 HSP 3 Score: 65.4698 bits (158), Expect = 5.895e-10 Identity = 52/203 (25.62%), Postives = 88/203 (43.35%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN----KLSKDSMRLN-WNIIRENNFPLDE 699
L+++W K G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L L +DS R + + E PLDE
Sbjct: 17 LLEQWE-KDHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQLQEVALRQDSKRPSPRKLSSEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Mouse
Match: Dcaf1 (DDB1 and CUL4 associated factor 1 [Source:MGI Symbol;Acc:MGI:2445220]) HSP 1 Score: 265.388 bits (677), Expect = 1.952e-71 Identity = 195/703 (27.74%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN--------------------ILSSSTPKPISADSNTSIL-------------------SIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I +R S P P + + S L + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 723 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTREADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIASRLGSHATVGASAPSAPPAHPPPRPPQGSLPLPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1389 HSP 2 Score: 100.138 bits (248), Expect = 1.592e-20 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 319 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 501 HSP 3 Score: 65.855 bits (159), Expect = 4.879e-10 Identity = 52/203 (25.62%), Postives = 88/203 (43.35%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN----KLSKDSMRLN-WNIIRENNFPLDE 699
L+++W K G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L L +DS R + + E PLDE
Sbjct: 17 LLEQWE-KDHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQLQEVALRQDSKRPSPRKLSSEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Mouse
Match: Dcaf1 (DDB1 and CUL4 associated factor 1 [Source:MGI Symbol;Acc:MGI:2445220]) HSP 1 Score: 258.84 bits (660), Expect = 2.061e-69 Identity = 195/709 (27.50%), Postives = 328/709 (46.26%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN--------------------ILSSSTPKPISADSNTSIL-------------------SIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVV------ATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I +R S P P + + S L + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY + AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 723 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTREADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIASRLGSHATVGASAPSAPPAHPPPRPPQGSLPLPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIVMFYFSATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1395 HSP 2 Score: 100.138 bits (248), Expect = 1.554e-20 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 319 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 501 HSP 3 Score: 65.855 bits (159), Expect = 4.924e-10 Identity = 52/203 (25.62%), Postives = 88/203 (43.35%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN----KLSKDSMRLN-WNIIRENNFPLDE 699
L+++W K G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L L +DS R + + E PLDE
Sbjct: 17 LLEQWE-KDHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQLQEVALRQDSKRPSPRKLSSEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Match: sp|Q9W2F2|DCAF1_DROME (Protein mahjong OS=Drosophila melanogaster OX=7227 GN=mahj PE=1 SV=2) HSP 1 Score: 336.265 bits (861), Expect = 3.094e-93 Identity = 341/1432 (23.81%), Postives = 578/1432 (40.36%), Query Frame = 1
Query: 97 ILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYI---------TSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLE---------------SLNKLSKDSMR---LNWNIIREN-NFPLDEGSNASVRDMLMSQICGVWNLAT-----------------------PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDY------TYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTW-----------KHPYISDRSNIIKVIYSKAG---------FFEDAYNNFH-DIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRP-LQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSST-------------PKPISADSNTSILSIFKPKLYRENLNQTSI---------MTKSVPQN---PG--------------KTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNIL--NY-ITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN--LENTKNGRL--LMASSSFSRRNNGVL-----TLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE--SNEDVGSYAQCRVFSVGYK 3996
+ ++I KW +QT G++P L LAE E E+ + +DPDP D R P + + Y + L F+ L+ +Y+ SRS E L+ +A R + ++ + +F E + NRI+ W+ P+ Y+T + + D I R I L+ + + RL S++ LS DS L+W N + P N S SQ N++ P T + L++ FL + E++ + + + V+ L+ +L D L +E L+ L LLCH+ +EF G+ LLL +PRPS+A +S +Y L Y + ++++ + + L++ L+I+ CH S++C+ + + + L+ F+ +G R + N +++L + + + + D+ +++ + +K +E N+ L + + P S N PT T+ +H I + + G F D N+ + + +LD+LS+ C+ + + + K T +L +S S + +KS L L C P ++ SL+ T RK + + E+IE+V W + N I LL +++ D +R C L+G++R + + ++ KLP F G L+ LM++ + E+ EH F A L+ + G+T ++ D + K ++ +T+IQ++ Q+L LI+ HL+ GL+ A +L+++ LP+ S + D K S + + +R ++++ P A + + + P N QT I +++S+ + PG K ITLN IV +L QH+ C NP++ CP+F L+ H CP KP+ +L NY +T R + +R RYVH F P + +D + D FT K + G + G VF D G SN N ++ K R L+ +SSF R +L F ++ R D T Y EFS+T + + TQ++ A + D+ TGS + + + + L T NRAT D L+LS G LWDVR S +E +H+FD +SGVFHPN LE+I + VWD+RT+ LLQ +P L F+ Y + F D+ DYS +AT++ + I+ L+V +AV+E S + ++++VG K
Sbjct: 113 LTQIIDKWEQQQTQNGYDPVPTLRSLAEIFEREKDVYRRKDPDPLDSRHPYRADPSCQYGLLLKLLFRKDTFMGKLLNDYLRENYFSRQNVSRSSLE-LNILACRLILEIMPGMETSAVFQTAEG---DGTINRIYSWAEDSIEPLQSYATGLLAEAMEVSDIAINFRDLN-IRLVPKMIKRLHMLLAISKSATSDVNTSMHNLSADSSTAGMLSWVACASNASAPQSPQHNGSGLGASSSQHGDASNMSILFENSRDAFSVSRYYKRMYIPLHPATADTSQMLIMRFLTSLGEYQEFLAMAFENNVMQLIFGYLENLDRRDTCLAYEVLKYLASLLCHKKFALEFISH-GGLELLLKVPRPSLATTGVSIAIYYLAYCEDAMERICSMQRPLISELVRYALWILGRCHDSSKCHATMFFSLSFQFKVILDEFDAQDGLRKLYNVISVLKILDPSHNDSDNDSDFNEDVECASRQMVRHVCVALKRYMEAHFF-------YKYNSFLCQTNAASPAPSSAHYFNQNPTVAAKLTFDQLNDQIRTLQEHTSIRAHWQPVDQLMKLGGITMLLRIIAFSYDWVNSGRSETVRSALDVLSVCCIIPRVYVVLCERLLMLDKTTTSGFCSVLGAAAGEIS-SDAEVIKSALAVLCHCVCSPIIRKDSGTSLIKFGTSSRK-NKANHKYAEELIERV------------------------------------------WESVCSNNGIVVLLSLMQTKGPITDADCIRGMACRALAGLARSDRVRQIVSKLPLFASGQLQTLMRDPILQEKRAEHVIFQKYALELLERVSGKTKP-LNNPLDPSLSNMHKANVIAQTRIQYNKQQLYQLIFEHLESNGLSQTAQMLQREVGLPLQTPTTRSFHQSPFDYKSLPSGSSSLSRNRLRSRMQDVNAAIMGNGDLNRSFGEDSSPAGAGGSNAGDGVSIPNFSSLNTTQTPIKIRRTDRSSVSRSIQKQAMEPGGMSVGLAEDGQLHPKRITLNTIVTEYLTNQHSLCNNPVTTCPQFDLYEPHKCP----DPKPSRLLSSNYNLTSRHARTQAGFNTSRFDRRYVHTHFSPWRSIRSAD-YEDLEFTCCDLAGKYIIVG---TQQGDGRVFNMND--------GVEQFFSNCHNFSVDAIKANRAGDLVITSSFWRTPTSILWSIADDEFKLKLRLPDVT------------YCEFSQTVQDRLLGTQNECATLFDINTGSKVASFTP---TIPNLYTKNRATLCRTDELILSDGVLWDVR-SGKE-------IHKFDKFNQCISGVFHPNCLEIIANTEVWDLRTFHLLQTVPVLDQRNCTFSPM-HVIYGASLGADRDHDMETTTYDTSFNVLDAYDYSSIATIDVKRNINDLSVSANGSLIAVVEDYSGYESKQETYVKIYAVGVK 1446
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Match: sp|Q9Y4B6|DCAF1_HUMAN (DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3) HSP 1 Score: 266.544 bits (680), Expect = 6.364e-71 Identity = 194/703 (27.60%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN---ILSSSTPKPISADS------------------------------------NTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I R + +S P +A N + + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 724 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIATRLGSHAAVGASAPSAPTAHPQPRPPQGPLALPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLMEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1390 HSP 2 Score: 100.138 bits (248), Expect = 1.308e-19 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 320 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 502 HSP 3 Score: 62.7734 bits (151), Expect = 3.089e-8 Identity = 42/175 (24.00%), Postives = 77/175 (44.00%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN 630
L+++W K+ G + L +++ IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L
Sbjct: 17 LLEQWE-KEHGSGQDMVPILTRMSQLIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQ 183
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Match: sp|Q80TR8|DCAF1_MOUSE (DDB1- and CUL4-associated factor 1 OS=Mus musculus OX=10090 GN=Dcaf1 PE=1 SV=4) HSP 1 Score: 265.388 bits (677), Expect = 1.366e-70 Identity = 195/703 (27.74%), Postives = 328/703 (46.66%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFN--------------------ILSSSTPKPISADSNTSIL-------------------SIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
K+WN+++ N I LL +L + + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I +R S P P + + S L + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 723 KMWNVVQSNNGIKVLLSLLSIKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTREADLPMTAASHSSAFTPVTAAASPVS-LPRTPRIANGIASRLGSHATVGASAPSAPPAHPPPRPPQGSLPLPGPSYAGNSPLIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGFTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1389 HSP 2 Score: 100.138 bits (248), Expect = 1.113e-19 Identity = 56/184 (30.43%), Postives = 96/184 (52.17%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 319 PMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQG 501 HSP 3 Score: 65.855 bits (159), Expect = 3.413e-9 Identity = 52/203 (25.62%), Postives = 88/203 (43.35%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN----KLSKDSMRLN-WNIIRENNFPLDE 699
L+++W K G + L ++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L ++ ++F KE +F+W+ P+ YST + G + D + + L++ + RL L L +DS R + + E PLDE
Sbjct: 17 LLEQWE-KDHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGRADPECMLGHLLRILFKNDDFMNALVNAYVMTSREPP-LNTAACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAREADQPLRTYSTGLLGGAMENQD-IAANYRDENSQLVAIVLRRLRELQLQEVALRQDSKRPSPRKLSSEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Match: sp|Q21106|DCAF1_CAEEL (DDB1- and CUL4-associated factor homolog 1 OS=Caenorhabditis elegans OX=6239 GN=dcaf-1 PE=3 SV=5) HSP 1 Score: 214.542 bits (545), Expect = 1.055e-54 Identity = 184/705 (26.10%), Postives = 337/705 (47.80%), Query Frame = 1
Query: 2038 HLELQNKLWNLIRCYNAIPKLLKIL--EVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKME------IVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDR-ENLSLYDDVVDEKI-----TFSRL----PQTPKRAIENRFNILSSSTPKPISADSNTSILS--------IFK-PKLYR---------ENLNQTSIMTKSVPQNPGKTIT-------LNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNILNYITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLED---GLFFAGENSGIVFTDVDLAQASVEIGEINGTSNA-SNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDI-VSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE------SNEDVGSYAQCRVFSVG 3990
HLE ++W +R + I L+ ++ ++PL+ D S+R + L+G++R ++ +L KLP L+NLM+E V ++ HA FC A +L++ + G+ K+ D + +++ E ++ TQ+ ++ ELL LI+ HL ++ L+ VA +L+ +A LP DR + S+ ++++ + FS++ P R +E+ +S+ P ++ S+ ++ + +F P L R + L + K P PG++ + LN IV + R QH+ C NP++ CP FSL +H CP + + TN++ I+ R+ D + R+ ++ + N + D F+ E GLF N + + +VD ++ G N +A +N+E +K+G +++ SS+FSR + + L ++R H Y+ +F+ T + + T A V D ET +L T + I N A+FS DD L+ + G LWDVR ++ +H FD L I + G FHP+G +++I S V+D+RT+R+L ++P L ++ FN G+ Y + +++ + + + F+ F++RDYS + T + + L +D + VIE S+ + + Q ++ +G
Sbjct: 723 HLE---RMWTEVRKTDGIMALVNLINCKIPLTEAD--SIRKTATNTLTGLARHPEVRQILAKLPLIAHNGLQNLMREPVCSDKRDIHAAFCKEAVQLLQVIYGR------KIHDQQGKEIQSSEKSHRQWVIENTQVSFNQAELLQLIHDHLLKSKLDSVAAMLKSEAKLP--DRPASRSINTPILNKPLPSSGNNFSKINDTYPTLAPRTLESEIGGISARRPSNAASLSSPAMATRSHSTDDDVFATPTLPRRYTTSGAFPKKLMISPARQKLRPLTPGESSSGYRPIKDLNSIVTDYFRNQHSTCKNPVTTCPPFSLFYQHKCPEL---SYQTNVVRNISLRTLDQELLRPHERVYSQWTNERTIFSRFRNWKTIHDHDESYTKATFSVDDEHLIVGLF----NGEVHWINVD---TGLDEGHTNCHGSALTNIEPSKDGSMMLTSSAFSRPLSALWRLGEA---------LQRVHTYREDSCVKFANTTMQRIVGTCRDKATVYDTETNHVLDTYLSG--IDGLQYEKNYASFSPDDKLIFNDGLLWDVRKK-------NSAIHVFDRLSKITLFGTFHPHGTQIVINSEVYDIRTFRMLHHVPELNRCQVSFNSTGNIMYA-TEVTDVHCPDYDEKIFSSFRTFETRDYSALTTFEGRRPVIDLCASHQDQKMCVIEKVRPQMSDYMIQASTQLKIVEIG 1385 HSP 2 Score: 93.9745 bits (232), Expect = 8.299e-18 Identity = 53/185 (28.65%), Postives = 104/185 (56.22%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYG-MLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
P++ AT +R ++ +L E++ L+ + L ++ ++ E+ D+RLTF+AL+ L LL HR +EF + GI LL +P+ S+A+ + CLY + Y ++++ + Q+S + ++ ++ +L+ +E H S M Q L + + L F++ +GPR + N +A L T++ N++
Sbjct: 315 PLSLATYQRFILQYLAACGEYQDLLLQTFEGNALEILFDYIDLEKSKDVRLTFDALKYLTSLLVHRKFALEFVNK-GGIPALLKVPKTSLASVGVVTCLYYIAYSNDVMEILCQMSDEIVDETVQYVLWCLEHSHESGMASACMFFSQGLFYKAI-LRRFDQYDGPRKLHNYIATL-TLMQNNED 496
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Match: sp|Q9M086|DCAF1_ARATH (DDB1- and CUL4-associated factor homolog 1 OS=Arabidopsis thaliana OX=3702 GN=DCAF1 PE=1 SV=2) HSP 1 Score: 114.775 bits (286), Expect = 4.941e-24 Identity = 112/436 (25.69%), Postives = 199/436 (45.64%), Query Frame = 1
Query: 2758 PQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDS-NKPTNILNYITKRSYDSNHHTAN-NRMLHRYVHRSFKP-RVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGR--LLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSG--YTEFSKTNDTKFIITQD---KIAQVVDVETGSILHTCSNDDLIVTTLRTT--NRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTY--KDSCNIYTSNPIARGQN----IFQCFDSRDYSVVATVNTNKVISSLTVDPKD--LGVAVIESNEDVGSYAQCRVFSVGYKWPS 4005
P NP + ++L+ +V +L+ QH QC PI+ P SL + H+CP P N+ + R S + + NR ++V FK R +E+ +F C A G N + + + EI +I S+ S LE+ + + + SR +L+ + + + D + + + F G +FS + ++ + K + DV+T S C VT+ R+ + FS D L+L G LWD R + + RFD D G FHP+ EVII S +WD+RT++LL+++P+L + I FN +GD Y ++ ++ ++ R ++ F+ D+ +YS +AT+ ++ + +P D LG+ +E ED+ ++ R++ +G + P+
Sbjct: 1372 PSNPER-LSLDSLVVQYLKHQHRQCLAPITTLPPVSLLHPHVCPEPKRLLEAPLNMTGRLGTRELQSFYSGVHGNRRDRQFVFSRFKSWRSFRDETALFT--------CIA-------LLGGTNH------IAVGSHAGEI-KIFEASSGSMLESVSGHQAPVTLVQPYVSRDTQLLLSSSSSDVQLWDASSITGGPRHSFDGCKAAKFSNSGLQFAALSCEASRKDVLLYDVQTCS---PCQKLTDTVTSSRSNPYSLVHFSPCDTLILWNGVLWDRRIPEK--------VRRFDQFTDYGGGGFHPSRNEVIINSEIWDMRTFKLLRSVPSLDQTAITFNSRGDVIYAMLRRNIEDVMSAVHTRRVKHPLFAAFRTLDAINYSDIATIPVDRCLLDFATEPTDSFLGLITMEDQEDM--FSSARMYEIGRRRPT 1771
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Match: A0A4W3HQL5 (LisH domain-containing protein OS=Callorhinchus milii OX=7868 PE=4 SV=1) HSP 1 Score: 377.867 bits (969), Expect = 2.682e-105 Identity = 355/1449 (24.50%), Postives = 610/1449 (42.10%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTY----------IAGHITKEDDQVIPQRKSTYINLISQTMTRLESLN-----------------KLSKDSMRLNWN----------IIRENNFPLDEGSNASVR-----------------------DMLMSQICGVWNLATP-----------MNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKD----------YTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPS----------ETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFED--AYNNFHDIINCSLDILSLLCVSNKFIIKFLD----FAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVG-DMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSR---------LPQTPKRA---IENRFNILSSSTP---------------KPISADSNTSI---------------LSIFKPKLYREN-----LNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQ---CRVFSVG 3990
L+++W + + G N L ++++ IE E E+ DPDPFD+R P + + + L +N +F+ +L+ Y+ S S + ++ A R L + ++F KE +F+W+ P+ Y+T IA + +E+ Q++P +L Q + R + + + ++++ +++ + E +F L+ A+ R D + S+ W+ +P + A ++RL++ +L + E++ L+ G L+ ++ ++ +D++LTFEAL+ L LL H+ +F + G+ LL IPRPS+AA +S CLY L Y + +++V L L ++ L+++E H S RC+ + L +F+K +G R ++N ++ L + E+Q D +T L + + I LE + SL G L P E + ++ C P + W+ I + + ++++ D Y D + +LD+L++L V K + + ES + T + IL + + + KS L + C P + +I T +RK N Q K +N+ K+WN+++ N I LL +L V + D +R+ C L G+SR + + ++ KLP F+ G ++ LM+E V ++ EH +FC A LI + G+ S +G D+ +L+K ++V +T+I + +ELL LI +HL GL + A L ++ +LP V F+ LP+TP+ A N+ S STP P A+ + I S+ K KL R+ NQT + K + ++ +L+ I+ +LR QHA+C NP+ CP FSL H CP + P N + + R+ + + R+ + F+P + ES D+ +G C A + G +G +L E S S+LE +K+G LL+ S+S+ + + + + +V +H + Y EFSK + + I T++++A + DV+TG + T N DL R N ATF+ D+LVL+ G LWDVR +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L RI+FN G Y D ++ + + F+ FD+ DY +AT++ + I L D KD +AVIE+ + + + CR++ VG
Sbjct: 17 LLEQWE-RDSNSGTNVIPILTKISDLIEKETEEYHKADPDPFDDRHPGRADPECMLGHLLKILFKNDDFMNSLVNAYVMS-SRDAPVNTAACRLLLDIKPGLETAVVFQ-----EKEGIVENLFKWAREAEEPLRTYATGLLAGAMENQDIAANYREENSQMVPLMLQRLRDLQKQDLERNQKIKWQSPRKPPLNPPLEPLLPMDEEAVDMDYGDTERAPDGEEGLEEFSFQLNSMCKANSRVNSIGEDGRKVPKHRLSFSGLDPDRICSEHSNSWSEMSPWVIGNNYNLYPLTSAIEQRLILQYLTPLGEYQELLAVFMQLGARDLLMFYIDLKQTNDVQLTFEALKYLASLLLHKKFAADFVAQ-GGVQKLLEIPRPSMAATGVSLCLYYLAYNQDAMERVCLLPHFVLSDVVSYTLWLLECSHESGRCHATMFFSISFAFRSVLELFDKQDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTAKHTCMALRRYFEAHLGIKLEH--VKRSLQRTEG---GALIHPQPPYKACSYTHEQVVEMVEFLIECGPARL---FWEPAEIFHKLSCVQLLLQLISIACDWRTYYGRSDTVRSALDVLAILTVVPKTPLLLAEPVDVLDESGSAVTTVGMSIILGVAEGDIFVNDAETQKSALQVIMNCVCGPDKRISSIGKFLSGTPRRK------------------NSQ---------------------TPKSSENV----LTKMWNVVQANNGIKVLLSLLTVKMPITDADQIRSLACKALVGLSRSSSVKQIISKLPLFSSGQIQQLMREPVLQDKRHEHVKFCKYASELIERISGKPLS----IGSDVSLARLQKADVVAQTRISFSEKELLLLIRNHLVSHGLQETAATLTKEGDLP-----RTPAIQPVPSHPTAFTPVAAGTSPIVLPRTPRLANGICSRTINLTSVSTPCQAKPSALQVSCSGTGPSCANGSPIIGKISFSKEKPSPCNGCSLRKQKLIRQKSDYGAYNQTPAIKKQLDRHLPSPPSLDSIITEYLREQHARCKNPVVTCPPFSLFTPHQCPEPKQRRQAPLNCTSRVACRAAFPKYGGVDGGCFDRHLIFSRFRPISVFRES----DEEGSGFTCCAFSARERFLMLGTCTG-ELKLYNLFSGQEEATYACHNSAISHLEPSKDGSLLLTSASWGQPLSALWGMRSV---------FDMKHSFPDDHYVEFSKLSQDRVIGTKEEVAHIYDVQTGLNILTLYNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSKQA--------VHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRIVFNNTGTVIYGAMLQADDEDDMMEERMKSPFGSSFRTFDATDYKPIATLDVKRNIFDLCTDTKDCYLAVIENQGSMDALSMDTVCRLYEVG 1373
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Match: W4YS11 (LisH domain-containing protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1) HSP 1 Score: 360.147 bits (923), Expect = 1.267e-98 Identity = 309/1184 (26.10%), Postives = 539/1184 (45.52%), Query Frame = 1
Query: 670 IRENNFPLDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKN-ARKDYTYFGLLKTILNT---MKICLEQSLINW--SLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTW--KHP---YISDRSNIIKV--------IYSKAGFFEDAYNNFHDIINCSLDILSLLCVSNKFIIKFLD---FAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRP---LQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSSTPKPISADS-------NTSILSIFKPKLY-----------------RENLNQTSIMTKSVPQNPGKTI----------------TLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIG-DSNKPTNILNYITKRS-YDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGL--EDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTY---KDSCNIYTSNPIAR--GQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
+ EN L S A + ++ C P+N Q+R ++ +L + E++ L+ +++ +G + L+ ++ + +D+RLTF+AL+ L LLCH+ +EF E ++G+ LL IPRPSVAA +S CLY L Y + ++++ L S L ++ +L+++E H S RC+ + + + L++F++ +G R + N+++ L + E QN + + D F +TI +T +K E L S+ A N G P E P+ + V T ++T + P + + +IK+ I + A +++ Y+ +++ +LD+L+++ V+N+ ++ + ++ + ++ G+ LS V+ K+ L + C P L GS + N + + R ++T++IEK +W +R N I LL +L V + S+R C L G++R + ++ KLP F++ L+ LM+E V ++ EH +FC A LI + TG + D ++ K IV +T+I++DS+ELL LI++HL+ GL + A +L ++A L + + S + + SR + A + SSS P++ S NTS S+ P++ R + + S + P K +L+ IV +LR QHA C NP+ CP FSL H CP N P N + + +RS Y ++ R +V+ F P +++ DD + F+K D + G +G + T +L + E + S +E +++GRL++ SS++S + + T+P+ R+ + + EFS+ + + I T+D A + DV TG ++ T + L + T N ATF D LVL+ G LWDVR + +++FD ++ + G+FHP+GLEVII S +WD+RT+ LL +P L RI+FN G Y DS + + G +I + FD+ DY +AT++ + I L DP+D +A++E S + CR++ VG
Sbjct: 361 LSENEVELSNSSWAEMSRYIIGSQCMF-----PLNPIMQQRFILQYLTPLGEYQELLGAMFENGSMELVLHYIDLNKTNDVRLTFDALKYLSSLLCHKKFAMEFLE-LNGLQKLLEIPRPSVAATGVSLCLYYLAYNEDTMERICLLPSPVLLQMMNYMLWLLECSHESGRCHATMFLMTSLGFGAVLDLFDRKDGLRKLFNTMSTLSILDPEGQNSDQSNNDDDVFSSRQTIKHTTLALKRYFETHLAIKVDSIKRSYARNQG--QTPPEPIPPYKNIPVTPETTQENMETMLEQAPLRLHWTPAGTLIKLQGIQPLLQIIALATVWKN-YSARSEVVKAALDVLAVVTVTNRGQLQLCEQVHLPDNSEIVAMNIVNGVA--EGEVLSDPDVQ--KAALQVISNCVCGPSTRLGGSMGRFMSNSAKKNR----TSIRSSTDIIEK------------------------------------------MWETVRTNNGIKTLLNLLTVKTPITEADSIRALSCKALCGLARSEVVRQIISKLPIFSRSGLQTLMREPVLQDKRTEHLKFCKCASELIERV---TGKAMSLGADATLSKIHKANIVAQTKIRYDSKELLQLIHNHLRGQGLGETAKILEREAGLRLANHSTSSAVSSLQLTPTSTSRSLRNTHLAHGSAAASSSSSQSDPVNQPSTSSGTPTNTSTASLPPPRIVFGPDSRASPSSARNAPRRRVIREKSSHSHLTPLGQSKRAASLGNIASSRPCKSPPSLDIIVSQYLREQHAHCSNPVVACPSFSLLEPHQCPEPKFRQNAPINATSRLFRRSIYPAHGGRDGARCSRHFVYSRFHPMQTFRDTE---DDSWFTCCSFSKHANPRDQFLWLGNYAGELKT-YNLYSGNEETSYVCHDSPIRLVEPSRDGRLVLTSSTWSHPMSALWG--------TEPS-FDRKFSFNDDVHVEFSRASQDRIIGTKDDRAHIYDVATGKLILTLQDGQL--SNNYTNNCATFDPTDELVLNDGVLWDVRSAKH--------IYKFDQFQNKIGGLFHPSGLEVIINSEIWDIRTFHLLHTVPALDQCRIVFNSLGTVIYGVIFQSDSDDELVEERMKSPFGSSI-RTFDATDYKPIATIDVKRNIFDLATDPQDKYLALVEQQGGADSLDVESICRMYEVG 1458 HSP 2 Score: 68.9366 bits (167), Expect = 1.261e-7 Identity = 48/180 (26.67%), Postives = 82/180 (45.56%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTY----------IAGHITKEDDQVIP---QRKSTYINLISQT 606
L+ +W G +P L ++AE +E E F D DPFD+R P ++ D+ L +N F+ L+ +YI S + E ++ +A R L V+ +IIF+ + F NR +W+ P+ Y+T IAG++ + +++P QR + N S+
Sbjct: 15 LLTQWDQDHG-SGSSPIPRLKKMAEIMEMEVENFLKLDADPFDDRHPGRVDPTCALGDLFTSLFKNDNFMSKLVNDYIMSSRDKE-INTLACRLLLDVVPGLETSIIFE-----ETDGFVNRFVDWATEAEEPLKSYATGLLAAAVEVQDIAGNLKDINARLVPVMLQRLRGFKNAASEA 187
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Match: A0A401SWD4 (LisH domain-containing protein (Fragment) OS=Chiloscyllium punctatum OX=137246 GN=chiPu_0013166 PE=4 SV=1) HSP 1 Score: 357.066 bits (915), Expect = 9.877e-98 Identity = 310/1165 (26.61%), Postives = 519/1165 (44.55%), Query Frame = 1
Query: 766 PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKD----------YTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFP-------SETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFED--AYNNFHDIINCSLDILSLLCVSNKF------IIKFLDFAESDTKAT-IKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVG-DMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLP----IGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFNILSSSTPK------PISADSNTSILS-------------------------IFKPKLYREN-----LNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGT-----SNASNLENTKNGRLLMASSSFSRRNN---GVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTY-------KDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIE----SNEDVGSYAQCRVFSVG 3990
P+ A ++RL++ +L + E++ L+ G L+ ++ ++ +D++LTFEAL+ L LL H+ EF +G+ LL IPRPS+AA +S CLY L Y + ++++ L L ++ L+++E H S RC+ L L +F+ +G R ++N ++ L + E+Q D +T L + + + I LEQ + SL G + P S T +++ I W+ + + + ++++ D Y +D + C+LD+L++L V +K + +D S A + +I G+ + + + KS L + C P + +I N T +RK +L N + E V K+WN+++ N I LL +L V D +RT C L G+SR + + ++ KLP F G ++ LM+E V ++ EH +FC A LI + G+ S +G D+ +L+K ++V +T+I + +ELL LI +HL GL+D A +L ++ +LP I S + LP+TP+ A I +R L++ P ++TS LS + K +L R+ NQT + K + ++ +L+ I+ +LR QHA+C NP+ CP FSL H CP + P N + +T RS + + R+ + F+P + ESD + +G C + G +G +L ++ G+ GT S ++LE +K+G LL+ S+S+ + + G+ ++F++++ TD +H Y EFSK + + I T++++A + D++TG + T N DL R N ATF+ D+LVL+ G LWD+R + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L RI+FN G Y D + +P F+ FD+ DY +AT++ + I L D KD +AVIE S + + CR++ VG
Sbjct: 333 PLTSAIEQRLILQYLTPLGEYQELLAVFMQLGARELLMYYIDLKQTNDVQLTFEALKYLASLLLHKKFAAEFVAH-EGVQKLLEIPRPSMAATGVSLCLYYLAYNQDAMERLCLLPQYVLSDVVSYTLWLLECSHESGRCHATLFFSISFAFRSILELFDLQDGLRRVVNLISTLEILNLEDQGALLSDDEIFASRQTAKHTCMALRRYFESHLGIKLEQ--VKRSLQRTEG---GAIIHPHPPCKACSYTHEQVMEMMEFLIEYGPARLFWEPAEVFHKLSCVQLLLQLISIACDWRTYYGRNDTVRCALDVLAVLTVVSKTQLLLAEPVDVMDEGSSTVTAVGMSIILGVA---EGDIFANDAETQKSALQVIINCVCGPDKRISSIGKFNSGTPRRK-----NLQNPKSTESVL--------------------------------------TKMWNVVQANNGIKVLLSLLTVKTPITDADQIRTLACKALVGLSRSSAVKQIISKLPLFTSGQIQQLMREPVLQDKRHEHVKFCKYASELIERVSGKPLS----IGSDVSLARLQKADVVAQTRITFSEKELLLLIRNHLVSHGLHDTASMLTKEGDLPRTPAIQAAPPHSPAFTTTAPGTSPVSLPRTPRLANGISSRTINLTAFPPSCQAKVAATQGATSTSGLSCPNGSPIIGKISFSKEKPSPCNGTNLKKQRLIRQKSDYGAYNQTPAIKKQLDRHLPSPPSLDSIITEYLREQHARCKNPVVTCPPFSLFTPHQCPEPKQRRQAPLNFTSRVTHRSAFPKYGGVDGGCFDRHLIFSRFRPISVFRESD----EEGSGFTCCTFSARERFLMLGTCTG------ELKLYNLFSGQEEGTYACHNSAITHLEPSKDGSLLLTSASWGQPLSALWGMKSVFDMKHSFTD------DH------YVEFSKLSQDRVIGTKEEVAHIYDIQTGQNILTLYNPDLANNYKR--NCATFNPTDDLVLNDGVLWDIRSTQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRIVFNNTGTVIYGAMLQADDEDDLIEVRMKSPFGSS---FRTFDATDYKPIATLDVKRNIFDLCTDTKDCYLAVIENQGSSMDALSMDTVCRLYEVG 1406 HSP 2 Score: 64.3142 bits (155), Expect = 2.547e-6 Identity = 47/207 (22.71%), Postives = 93/207 (44.93%), Query Frame = 1
Query: 97 ILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYST-YIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLNKLS-KDSMRLNWNIIRENNF----PLDE 699
+ L+++W ++ G N L ++++ IE E E+ DPDPFD+R P + + L +N +F+ L+ Y+ + S + ++ A R L ++ ++F KE +F+W+ P+ Y+T +AG + +D + + ++ + RL L + S ++ W R+ +F P+DE
Sbjct: 31 LTSLLEQWE-RENSNGQNIVPILTKISDLIEKETEEYHKADPDPFDDRHPGRADPECRLGHLLKILFKNDDFMNALVNTYVMT-SRDPPVNTSACRLLLDIMPGLETAVVFQ-----EKEGIVENLFKWAKESDQPLRTYATGLLAGAMENQD--IAANYREENSQMVPVMLQRLRDLQVQDLESSQKMKWQSPRKPHFTSLLPMDE 228
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Match: W5N7K9 (DDB1 and CUL4 associated factor 1 OS=Lepisosteus oculatus OX=7918 GN=DCAF1 PE=4 SV=1) HSP 1 Score: 356.295 bits (913), Expect = 1.754e-97 Identity = 329/1268 (25.95%), Postives = 558/1268 (44.01%), Query Frame = 1
Query: 427 FDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLNKLSKDSMRLNWNIIRENNFPLDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILP--------TMLGENQNKNARK--DYTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFEDAYNNFHDI--INCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTL------------SGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLE-LQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIG-DRENLSLYDDV-VDEKITFSRLPQTPK--RAIENRFNI------------------LSSSTPKPISADSNTSILS---IF-----------KPKLYREN-----LNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVG 3990
DG E KE + E+ L+ R + S+ ++ + E D+ +K+T + + R K +LN++I E SN+S +M I ++L P+ A ++RL++ +L + E++ L+ G L+ ++ ++ +D++LTFEAL+ L LL H+ EF G+ LL IPRPS+AA +S CLY L Y + +++V L L ++ L+++E H S C+ + L +F+K +G R ++N ++ L +L +++ ++R+ +T L + + I +EQ + SL G P P+ K T+ H + + + + Y + + FH + I L ++S+ C + + SDT + IL P T SGS V + M LG+ + +N + EI VI V D+R+++ + P+ N E + K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ G ++ LMKE V ++ EH +FC A LI + G+ G+++ +L+K +V +++I + +ELL LI +HL GL+D A L ++A+LP+ + S + V V + + LP+TP+ + +R S + P + SN S L +F KP++ R+ +Q+ M K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + PTN + +T R + + R+ + F+P + E AD+ +G C A + G +G VF + A S S ++LE +++G LL+ S+S++ + + + +V +H + Y EFSK + + I T++ IA + D+++G + T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVI+ + +WD+RT+ LL +P L RI+FN G Y D ++ + + F+ FD+ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 223 LDGQEE--KEGLEDSDVEFHLNSR---HKTSSRVSSTVKPELDEA-DGKKNTSVKKTERENGR--------KAKQKLNFSISEPERI-FSELSNSSWSEMSPWVIGTNYHL-YPLTPAIEQRLILQYLTPLGEYQELLAVFMQLGARELLMYYIDLKQTNDVQLTFEALKYLASLLLHKKFAAEFVAH-GGVQKLLEIPRPSMAATGVSLCLYYLAYNQDAMERVCMLPHSILSDVVGYTLWLLECSHASGGCHATMFFSISFSFRAVLELFDKQDGLRRLVNLMSTLEILNLEDQGALLSDDEIFSSRQTAKHTCMALRRYFEAHLAIKVEQ--VKQSLQRTEG---GAPVHPQ----PYYKAC-----------TYTHDQVVEMMEFL-IEYGPVRLYWEPAEVFHKLSCIQLMLQLISIACDWRTY------YGRSDTVRYALDVLAILTVVPKTQLLLAEPVDVLDESGSTVSTV-GMSIILGV--------AEGEVFVNDA-------EIQKSALQVVINCVCAPDKRISS-------IGKFISGTPRRRMPQNNKCTENVLTKMWNVVQSNNGIKVLLSLLTVKMPITDADQIRALACKALVGLSRSGTVKQIISKLPLFSSGQIQQLMKEPVLQDKRSEHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKANVVAQSRISFPEKELLLLIRNHLVTKGLHDTASALTKEADLPMAIHSHSSSAFSPVAVAPASSPAVLPRTPRLPNGVTSRIASHSSISATPSSSHGQVRPSTSQTQPPAAAPHSNGSPLIGRIVFTRERPSPCNSKKPRVLRQKSDHGAYSQSPAMKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVTTCPPFSLFTPHQCPEPKQRRQAPTNFTSRLTHRVVYPKYGGVDGGCFDRHLIFSRFRPISVFRE----ADEDESGFMCCAFSARERFLMLGTCTGQLKLYNVFNGQEEASYSCH------NSAITHLEPSRDGSLLLTSASWTYPLSALWGMKSV---------FDMKHSFLDDHYVEFSKLSQDRVIGTKEDIAHIYDIQSGQKILTLHNTDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIVNTEIWDLRTFHLLHTVPALDQCRIVFNNSGTVIYGAMLQADDEDDMMEQQMKSPFGSSFRTFDATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQDSMNMDTVCRLYEVG 1388 HSP 2 Score: 66.6254 bits (161), Expect = 6.416e-7 Identity = 49/201 (24.38%), Postives = 91/201 (45.27%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYST-YIAGHITKEDDQV-IPQRKSTYINLISQTMTRLESLNKLSKDSM-RLNWNIIRENNFPLDE 699
L+++W +Q + L +++E IE E E+ DPDPFD+R P + + + L +N +F+ L+ Y+ + E L+ A R L +++ ++F KE ++F+W+ P+ Y+T +AG + +D + S + L+ Q + L+ + S+ R + E PLDE
Sbjct: 17 LLEQWEREQQGSTQDLVSILTKISELIERETEEYHKADPDPFDDRHPGRADPECMLGHLLKILFKNDDFMNALVNTYVMTSRELS-LNTAACRLLQNIMPGLETAVVFQ-----EKEGIVEKLFKWAQEAEQPLRTYATGLLAGAMENQDIAANYREENSLLVPLMLQRLRELQEKDAESRQEFKRPSPRKALEPLLPLDE 211
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Match: A0A5N3XXL7 (Uncharacterized protein OS=Muntiacus reevesi OX=9886 GN=FD755_010280 PE=4 SV=1) HSP 1 Score: 351.288 bits (900), Expect = 5.099e-96 Identity = 342/1405 (24.34%), Postives = 597/1405 (42.49%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITS-----------RSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRK-STYINLISQTMTRLESLNKLSKDSMRLNWNIIRENNFPLDE-----GSNASVRDMLMSQIC-------GVWNLAT-----PMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKD----------YTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFP-------SETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFED--AYNNFHDIINCSLDILSLLCVSNKFIIKFLD----FAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRA--IENRFNILSS----------------------STPKPISADSNTSI-----------------LSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASN-----LENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFY----TYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSY---AQCRVFSVG 3990
L+++W K+ G + L ++E IE E E+ DPDPFD+R P +I GI ++ E + +RT T + R EN L + LR L L +T + ++ + L E + Y + E ++ + S ++ +T +R+ S K + ++R N + + + + G ++S D + ++ W + T PM A ++RL++ +L + E++ L+P G LM ++ ++ +D+ LTFEAL+ L LL H EF G+ LL IPRPS+AA +S CLY L Y + +++V L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q D +T L K + I LEQ + SL G+L P S T +++ I W+ + + + ++++ + Y +D + +LD+L++L V K ++ + E+D+ + I IL + KS L + C P +I T +RK + P+ + H K+WN+++ N I LL +L V + D +R C L G+SR + + ++ KLP F+ ++ LMKE V ++ +H +FC A LI + G+ G+++ +L+K ++V +++I + +ELL LI +HL GL + A +L ++A+LP+ + S + V S LP+TP+ A I R ++ + P P A ++ I + + + K +Q+ + K + ++ TL+ I+ +LR QHA+C NP++ CP FSL H CP + P N + + +R+ + + R+ + F+P + E A++ +G+ C A + G +G L +V G+ + N N LE +++G LL+ S+++S+ + + + +V +H + Y EFSK + + I T+ IA + D++TG+ L T N DL R N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L R++FN G Y D ++ + + F+ F++ DY +AT++ + I L D KD +AVIE+ + + CR++ VG
Sbjct: 17 LLEQWE-KEHGSGQDMVPILTRMSELIEKETEEYRKGDPDPFDDRHPGEI-CEGIVENLFKWAREADQPLRTYSTGLLGGAMENQDIAANYRDENSQLVALVLRRL-RELQLQEVTSRQESKRPSPRKLSSEPLL--PLDEEAVDMDYGDMAVDVVDGEQEEASGDMEISFHLESGHKTSSRVNSATKPEEGALRKNKSTKQADRESFRKAKQKLGFSSSDPDRMFVELSNSSWSEMSPWVIGTNYTLYPMTPAIEQRLILQYLTPLGEYQELLPIFMQLGSRELMMFYIDLKQTNDVLLTFEALKHLASLLLHNKFATEFVAH-GGVQKLLEIPRPSMAATGVSMCLYYLSYNQDAMERVCMHPHNVLSDVVNYTLWLMECSHASGCCHATMFFSICFSFRAVLELFDRYDGLRRLVNLISTLEILNLEDQGALLSDDEIFASRQTGKHTCMALRKYFEAHLAIKLEQ--VKQSLQRTEG---GILVHPQPPYKACSYTHEQIVEMMEFLIEYGPAQLYWEPAEVFLKLSCVQLLLQLISIACNWKTYYARNDTVRFALDVLAILTVVPKIQLQLAESVDVLDEADSTVSTVGISIILGVAEGEFFIHDAEIQKSALQIIINCVCGPDNRISSIGKFISGTPRRKLPQT-----------------------------------------PKSSEHT--LAKMWNVVQSNNGIKVLLSLLSVKMPITDADQIRALACKALVGLSRSSTVRQIISKLPLFSSCQIQQLMKEPVLQDKRSDHVKFCKYAAELIERVSGKPLLIGTDVSLA------RLQKADVVAQSRISFPEKELLLLIRNHLISKGLGETATVLTKEADLPMTAASHSSAFTPVTTAASPVS-LPRTPRIANGIATRLGSHAAVGASAPSAPAAHSQPRVPQGSLALPGPSHAGNSPVIGRISFIRERPSPCNGRKIRVLRQKSDHGAYSQSPAIKKQLDRHLPSPPTLDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPINFTSRLNRRASFPKYGGVDGGCFDRHLIFSRFRPISVFRE----ANEDESGLTCCAFSARERFLMLGTCTG------QLKLYNVFSGQEEASYNCHNSAITHLEPSRDGSLLLTSATWSQPLSALWGMKSV---------FDMKHSFTEDHYVEFSKHSQDRVIGTKGDIAHIYDIQTGNKLLTLFNPDLANNYKR--NCATFNPTDDLVLNDGVLWDVRSAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRVVFNHTGTVMYGAMLQADDEDDLLEERMKSPFGSSFRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQGSMDALNMDTVCRLYEVG 1331
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Nematostella
Match: EDO45169 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTY9]) HSP 1 Score: 247.284 bits (630), Expect = 2.261e-66 Identity = 203/704 (28.84%), Postives = 318/704 (45.17%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT-GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRL--------PQTPKRAIENRFNILSSSTPKP-------ISADSNTSILSIFKP-KLY--------------------RENLNQTSIMT--KSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSN-KPTNILNYITKRSYDSNHHTANNRMLHR-YVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDG--LFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNV-ENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAV---------WDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKD----SCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQ--CRVFSVG 3990
K+W+ +R N I LL +L V + S+R C L G+SR + I ++ KL FN G L+ LM+E V + + +H FC A L+ + G+ G+ + + ++ +V +T+I + +ELL L+Y HL GL + A +L ++A+LP + +++ ++L PQTP + ++ TP I SN +F+ K Y R+ N ++ KS + P TL+DIV FLR QHAQC NP+S CP FSL H CP + P+NI +T+R H N +R +V+ FKP + +SD T +F +EDG + +N + ++ E ++ S +K+G+ + SS F + + + E + + P +H Y +F ++ + I T ++ A + D TG ++ S D + N ATF+ D+LVLS G LWDVR +H+FD + VSGVFHP+GLE+II S + WD+R++ LL P+L +IFN GD Y K N+ + + ++ F+ FDS DY +AT++ K I L P D VAVIE N+ S + CR++ VG
Sbjct: 668 KMWSCLRNGNGIKVLLSLLLVKTPLVHADSMRALACKALCGLSRSDKIRQVIGKLQLFNSGQLQILMREPVLEDNISDHLVFCKYAAELLERVTGKPLGNATSSIPSL--SRITLAGVVAQTRISYPGKELLQLMYDHLMCKGLTETAKVLLREADLP---------NNRLIETPPKLAKLATPAPVSSPQTPTLS---KYRFSDPGTPAEKVCRSEYIGLPSNEQKNLLFRAVKCYSMKHDFGFFIRETGFLIFLRRKKGNDCRLLPDIKSGAERPPAPPTLDDIVTRFLRDQHAQCSNPMSACPPFSLLRPHKCPDPEFRHYAPSNITTRLTRREVTPRHGGYNGARFNRKFVYSKFKPLRGMRDSDE------TSMFTCVAFMEDGKNIILGTQNGELKM--FNIISGEEEASYSCNSAAISMCHPSKDGQFALTSSPFGMPSCALWNFGEIFEMKLSFPD----DH------YVKFGNLSEARVIGTDEQTAHIYDTSTGQLV--VSLADPASANHYSKNVATFNPTDDLVLSDGVLWDVRGKR--------LIHKFDKFNNFVSGVFHPSGLEIIINSEIVSFQFECTLWDLRSFHLLDTCPSLDQCHVIFNNGGDVIYGIKHLPDTEENMMSQRVLGPFESSFRTFDSTDYQPIATIDVKKTIFDLQSHPTDSIVAVIEQNQPTSSADESVCRLYEVG 1329 HSP 2 Score: 150.984 bits (380), Expect = 1.266e-36 Identity = 119/446 (26.68%), Postives = 194/446 (43.50%), Query Frame = 1
Query: 97 ILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVY----------STYIAGHITKEDDQVIP---QRKSTYINL-------ISQTMTRLESLNKLSK---------------DSMRLNWNIIRENNFPLDEG---------SNASVRDMLMSQICGVWNLA-TPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTM 1299
I L+ KW EG +P + L +A+ +E E + DPDPFD+R P + I L +N +F+ L+ +YI S E L+ +A R L +V+ ++F E R+F W+ + P+ Y S +AG E+ V+P +R +L I +R S K SK +S I R P + S + R S C + + +P+ A Q+RL++ +L + E++ L+P+++ L L+ ++ + D+ L+FEAL+ L LLCH+ EF + LL +PRPSVAA +S CLY L Y + +++V L L ++K L+++E H S C+ L L F+ +G R ++N L+ LP +
Sbjct: 10 ISSLLDKWSADDE-EGRSPIEALRRMADLVEGENESYHKLDPDPFDDRHPGRADPDCTLGHILKALFKNDDFMNKLVNSYIMSTREEFDLNCMACRLLLNVMPGLESAMVFQ-----ETEGLLARLFSWAKDAKEPLRSYAVGLLGFAMESQDVAGSFRDENAAVVPMMLRRLHILKDLQDLKQPAIDDIQSRAFSKTKTSKMKNEGSSTISSKSTTESSSAGSTIPRVKTTPSSKSHLSQLKSKRSRSPSRTSKRSYQCSPVSFSLSPLTLAMQQRLIMQYLTPLGEYQELLPTVFELKALDLIMHYITFKGQVDMYLSFEALKYLASLLCHKKFATEFVTHAH-VQRLLEVPRPSVAATGVSMCLYYLAYNEDAMERVCLLPHPVLNDMVKYALWLLECSHDSGHCHATLFFSLTFPFRAVLEFFDNGDGLRKLINLLSTLPIL 448
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Medaka
Match: DCAF1 (DDB1 and CUL4 associated factor 1 [Source:NCBI gene;Acc:101166224]) HSP 1 Score: 262.692 bits (670), Expect = 6.487e-71 Identity = 200/719 (27.82%), Postives = 327/719 (45.48%), Query Frame = 1
Query: 2053 NKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQ---TGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSR------LPQTPKRA--IENRFNILSSSTP--------------KPISADSNT-----------------------------SILSIFKPKLYREN-----LNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTY-------KDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVG 3990
K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ G ++ LMKE V ++ EH +FC A LI + G+ G+++ L++ +V +++I + +ELL LI +HL GL+D A L ++A+LP+ + S +P+ P+ A + R S TP +P+ SN +S K ++ R+ +Q+ M K ++ L+ I+ +LR QHA+C NP++ CP FSL H CP + PTN + T+R + + R+ + F+P + E AD+ +G C A + G +G VFT + A S +S ++LE +++G LL+ S+S+S + + + +V +H + Y EFSK + + I T++ +A++ D++TG + T +N DL + N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L RI+FN G Y + + +P F+ F++ DY +AT++ + I L D KD +AVIE+ + V + CR++ VG
Sbjct: 553 TKMWNVVQSNNGIKVLLSLLTVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSGHIQQLMKEPVLQDKRSEHVKFCKFAAELIERISGKPLLIGTDVSLA------WLQRASVVAQSRITFPEKELLLLIRNHLLAKGLHDTATALTKEADLPMTCLSHTSHSTSAFPSVAPPPPASPVATIPRAPRLASGVGARLGNHPSHTPIQASSHPQSRPSTSQPVVCSSNVLPSTSASHCNSSSPLIGRIIFSRERQTTCGTMSCKKARVLRQKSDHGAFSQSPAMKKQFDRHLPSPPALDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRHTRRVIYPKYGGVDGGCFDRHLIFSRFRPISVFRE----ADEDESGFMCCAFSARERFLMLGTCTGQLKLYNVFTGQEEASYSCH------SSAITHLEPSRDGSLLLTSASWSYPLSALWGMKSV---------FIMKHSFLGDHYVEFSKLSQDRVIGTKEHVARIYDIQTGQVTLTLNNPDLANNYKK--NCATFNPTDDLVLNDGVLWDVRTAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRIVFNNSGTVIYGAMLQADDEDEMMEMQMKSPFGSS---FRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQDSVNTDTVCRLYEVG 1233 HSP 2 Score: 86.6557 bits (213), Expect = 1.652e-16 Identity = 47/153 (30.72%), Postives = 81/153 (52.94%), Query Frame = 1
Query: 859 GVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
G L+ ++ ++ +D++LTFEAL+ L LL H+ EF G+ LL IPRPS+AA +S CLY L Y + +++V L L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 181 GACELLMHYMDLKQTNDVQLTFEALKYLASLLLHKKFAAEFVAN-GGVQKLLEIPRPSMAATGVSLCLYYLAYNQDAMERVCMLPHSILSDVVAYTLWLLECSHASGCCHATMFFSISFSFRAVLELFDRQDGLRRLVNLISTLEILNPEDQG 332 HSP 3 Score: 71.2478 bits (173), Expect = 9.159e-12 Identity = 40/150 (26.67%), Postives = 76/150 (50.67%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYST-YIAGHITKED 552
L+++W +Q + + L +++E +E E E+ DPDPFD+R P + + + L +N +F+ TL+ NY+ + E L+ A R L +++ ++F KE R+F+W+ P+ +Y+T +AG + +D
Sbjct: 17 LLEQWEREQHGSTQDLVNLLTKISELVEKETEEYHKADPDPFDDRHPGRADPECMLGHLLKILFKNDDFMNTLVNNYVMTSREFP-LNAAACRLLQNIMPGLETAVVFQ-----EKEGIVERLFKWAQEAEQPLRIYATGLLAGAMENQD 160
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Medaka
Match: DCAF1 (DDB1 and CUL4 associated factor 1 [Source:NCBI gene;Acc:101166224]) HSP 1 Score: 263.077 bits (671), Expect = 7.944e-71 Identity = 200/718 (27.86%), Postives = 327/718 (45.54%), Query Frame = 1
Query: 2056 KLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQT---GSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSR------LPQTPKRA--IENRFNILSSSTP--------------KPISADSNT-----------------------------SILSIFKPKLYREN-----LNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNK-PTNILNYITKRSYDSNHHTANNRMLHRY-VHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGI-----VFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTY-------KDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVG 3990
K+WN+++ N I LL +L V + D +R C L G+SR + ++ KLP F+ G ++ LMKE V ++ EH +FC A LI + G+ G+++ L++ +V +++I + +ELL LI +HL GL+D A L ++A+LP+ + S +P+ P+ A + R S TP +P+ SN +S K ++ R+ +Q+ M K ++ L+ I+ +LR QHA+C NP++ CP FSL H CP + PTN + T+R + + R+ + F+P + E AD+ +G C A + G +G VFT + A S +S ++LE +++G LL+ S+S+S + + + +V +H + Y EFSK + + I T++ +A++ D++TG + T +N DL + N ATF+ D+LVL+ G LWDVR + +H+FD +SGVFHPNGLEVII + +WD+RT+ LL +P L RI+FN G Y + + +P F+ F++ DY +AT++ + I L D KD +AVIE+ + V + CR++ VG
Sbjct: 753 KMWNVVQSNNGIKVLLSLLTVKMPITDADQIRALACKALVGLSRSTSVRQIISKLPLFSSGHIQQLMKEPVLQDKRSEHVKFCKFAAELIERISGKPLLIGTDVSLAW------LQRASVVAQSRITFPEKELLLLIRNHLLAKGLHDTATALTKEADLPMTCLSHTSHSTSAFPSVAPPPPASPVATIPRAPRLASGVGARLGNHPSHTPIQASSHPQSRPSTSQPVVCSSNVLPSTSASHCNSSSPLIGRIIFSRERQTTCGTMSCKKARVLRQKSDHGAFSQSPAMKKQFDRHLPSPPALDSIITEYLREQHARCKNPVATCPPFSLFTPHQCPEPKQRRQAPTNFTSRHTRRVIYPKYGGVDGGCFDRHLIFSRFRPISVFRE----ADEDESGFMCCAFSARERFLMLGTCTGQLKLYNVFTGQEEASYSCH------SSAITHLEPSRDGSLLLTSASWSYPLSALWGMKSV---------FIMKHSFLGDHYVEFSKLSQDRVIGTKEHVARIYDIQTGQVTLTLNNPDLANNYKK--NCATFNPTDDLVLNDGVLWDVRTAQA--------IHKFDKFNMNISGVFHPNGLEVIINTEIWDLRTFHLLHTVPALDQCRIVFNNSGTVIYGAMLQADDEDEMMEMQMKSPFGSS---FRTFNATDYKPIATIDVKRNIFDLCTDTKDCYLAVIENQDSVNTDTVCRLYEVG 1432 HSP 2 Score: 100.523 bits (249), Expect = 9.034e-21 Identity = 60/209 (28.71%), Postives = 108/209 (51.67%), Query Frame = 1
Query: 691 LDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQN 1317
E SN+S +M I ++L P+ ++RL++ +L + E++ L+ G L+ ++ ++ +D++LTFEAL+ L LL H+ EF G+ LL IPRPS+AA +S CLY L Y + +++V L L ++ L+++E H S C+ + L +F++ +G R ++N ++ L + E+Q
Sbjct: 325 FSELSNSSWSEMSPWVIGNNYHL-YPLTPEIEQRLILQYLTPLGEYQELLAVFMQMGACELLMHYMDLKQTNDVQLTFEALKYLASLLLHKKFAAEFVAN-GGVQKLLEIPRPSMAATGVSLCLYYLAYNQDAMERVCMLPHSILSDVVAYTLWLLECSHASGCCHATMFFSISFSFRAVLELFDRQDGLRRLVNLISTLEILNPEDQG 531 HSP 3 Score: 70.8626 bits (172), Expect = 9.596e-12 Identity = 40/150 (26.67%), Postives = 76/150 (50.67%), Query Frame = 1
Query: 106 LIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYST-YIAGHITKED 552
L+++W +Q + + L +++E +E E E+ DPDPFD+R P + + + L +N +F+ TL+ NY+ + E L+ A R L +++ ++F KE R+F+W+ P+ +Y+T +AG + +D
Sbjct: 17 LLEQWEREQHGSTQDLVNLLTKISELVEKETEEYHKADPDPFDDRHPGRADPECMLGHLLKILFKNDDFMNTLVNNYVMTSREFP-LNAAACRLLQNIMPGLETAVVFQ-----EKEGIVERLFKWAQEAEQPLRIYATGLLAGAMENQD 160
BLAST of DDB1-and CUL4-associated factor 1 vs. Planmine SMEST
Match: SMESG000070247.1 (SMESG000070247.1) HSP 1 Score: 2804.24 bits (7268), Expect = 0.000e+0 Identity = 1428/1428 (100.00%), Postives = 1428/1428 (100.00%), Query Frame = 1
Query: 43 MTENTDQNNQEPLIGESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLNKLSKDSMRLNWNIIRENNFPLDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDYTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFEDAYNNFHDIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPXXXXXXXXXXXXXXKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSSTPKPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNILNYITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVGYKWPSSSQYXXXXXXXXXXXXXXXXNQSGLDFVMDVDIDDINDFLMGTDDSSSESHIGDRDEENENLLXXXXXXXXXXXXXXXXXNXXXXXXXXXXXXSYGGLLTDDSSEFD 4326
MTENTDQNNQEPLIGESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLNKLSKDSMRLNWNIIRENNFPLDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDYTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFEDAYNNFHDIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPNNNNSNTNNNNSANKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSSTPKPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNILNYITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVGYKWPSSSQYDIDETDVDETDDEEIDNQSGLDFVMDVDIDDINDFLMGTDDSSSESHIGDRDEENENLLSITDSDSSDSERSSYDSNELDDMTEDEDDLSYGGLLTDDSSEFD
Sbjct: 1 MTENTDQNNQEPLIGESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHERTEFWGRDPDPFDERIPKKIPVAGIYADICNDLVENAEFIRTLITNYITSRSENEYLSKIALRFLCSVLNCCSLTIIFDGHENGSKESFYNRIFEWSLSERSPINVYSTYIAGHITKEDDQVIPQRKSTYINLISQTMTRLESLNKLSKDSMRLNWNIIRENNFPLDEGSNASVRDMLMSQICGVWNLATPMNEATQERLLIFFLRHIAEFETLMPSIYTSGVLPLMASWLRGERHDDIRLTFEALRLLMKLLCHRVIYIEFYERMDGINLLLSIPRPSVAANAISFCLYNLLYYVEIVDKVIQLSSQKLEHLIKVLLYIIETCHPSARCYGMLCIQCLIRQPLTLNIFEKLNGPRYILNSLAILPTMLGENQNKNARKDYTYFGLLKTILNTMKICLEQSLINWSLNTENADNTGLLAFPSETETPFSKLVVNCIPTAMKLQTWKHPYISDRSNIIKVIYSKAGFFEDAYNNFHDIINCSLDILSLLCVSNKFIIKFLDFAESDTKATIKLIFGILMRRPNTLSGSHVKALKSMLFFLGILCCRPLQGSRNISLLNKSTRKRKFEEIDSLTNTEVIEKVQINDQRVATKVSLPNNNNSNTNNNNSANKPRQNIHLELQNKLWNLIRCYNAIPKLLKILEVPLSPLDTVSVRTWVCHVLSGMSRCNDILLMLRKLPTFNKGILENLMKETVTPERMGEHAEFCTIARRLIRDLRGQTGSNIDKVGDMRPDQLRKMEIVGRTQIQWDSQELLNLIYHHLQQTGLNDVADLLRQQANLPIGDRENLSLYDDVVDEKITFSRLPQTPKRAIENRFNILSSSTPKPISADSNTSILSIFKPKLYRENLNQTSIMTKSVPQNPGKTITLNDIVETFLRTQHAQCPNPISICPKFSLHNKHICPSIGDSNKPTNILNYITKRSYDSNHHTANNRMLHRYVHRSFKPRVILNESDVFADDRFTGVFCFAKGLEDGLFFAGENSGIVFTDVDLAQASVEIGEINGTSNASNLENTKNGRLLMASSSFSRRNNGVLTLFNVENRCTDPTRMRREHEYQFSGYTEFSKTNDTKFIITQDKIAQVVDVETGSILHTCSNDDLIVTTLRTTNRATFSYDDNLVLSYGTLWDVRCSSREPPVVDTFMHRFDNLEDIVSGVFHPNGLEVIIGSAVWDVRTYRLLQNIPNLKSSRIIFNEQGDFFYTYKDSCNIYTSNPIARGQNIFQCFDSRDYSVVATVNTNKVISSLTVDPKDLGVAVIESNEDVGSYAQCRVFSVGYKWPSSSQYDIDETDVDETDDEEIDNQSGLDFVMDVDIDDINDFLMGTDDSSSESHIGDRDEENENLLSITDSDSSDSERSSYDSNELDDMTEDEDDLSYGGLLTDDSSEFD 1428 The following BLAST results are available for this feature:
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 3
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of DDB1-and CUL4-associated factor 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DDB1-and CUL4-associated factor 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 0
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of DDB1-and CUL4-associated factor 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of DDB1-and CUL4-associated factor 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025434 ID=SMED30025434|Name=DDB1-and CUL4-associated factor 1|organism=Schmidtea mediterranea sexual|type=transcript|length=4349bpback to top protein sequence of SMED30025434-orf-1 >SMED30025434-orf-1 ID=SMED30025434-orf-1|Name=SMED30025434-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1429bp MTENTDQNNQEPLIGESIILKLIKKWRTKQTLEGFNPSDHLLELAECIEHback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
