Cytohesin

Overview
NameCytohesin
Smed IDSMED30025418
Length (bp)1352
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cytohesin (SMED30025418) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytohesin (SMED30025418) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytohesin (SMED30025418) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytohesin (SMED30025418) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Homology
BLAST of Cytohesin vs. Ensembl Human
Match: CYTH2 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502])

HSP 1 Score: 247.669 bits (631), Expect = 3.185e-77
Identity = 128/378 (33.86%), Postives = 227/378 (60.05%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEELLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 376          
BLAST of Cytohesin vs. Ensembl Human
Match: CYTH2 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502])

HSP 1 Score: 243.432 bits (620), Expect = 1.170e-75
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEELLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLAGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. Ensembl Human
Match: CYTH2 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502])

HSP 1 Score: 243.047 bits (619), Expect = 1.853e-75
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG----LERFVAMNRGINEGGDLPEELLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. Ensembl Human
Match: CYTH3 (cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504])

HSP 1 Score: 241.121 bits (614), Expect = 1.041e-74
Identity = 126/365 (34.52%), Postives = 218/365 (59.73%), Query Frame = 3
Query:  183 IYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            I +R+K+L  DI+ L+ E  ++ T +  L  + + +      + + +G KKFN +P++GI++L+    +Q +P+ +A FL   + LNK  +GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y   NP +F++ +  Y++++A+IMLNT LHN   + +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  S++ ++IK CK++  G++++G+H  Y+I   S EE E WM +I+ SI
Sbjct:   27 IRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKT-TQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDE-FNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTA----ERFIAMNRGINEGGDLPEELLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379          
BLAST of Cytohesin vs. Ensembl Human
Match: CYTH1 (cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501])

HSP 1 Score: 240.35 bits (612), Expect = 1.772e-74
Identity = 126/376 (33.51%), Postives = 225/376 (59.84%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L++E  ++   ++ LG   + R      + + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG   + FN  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + N  +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   + EE E W+  I+ +I
Sbjct:   12 LTAEERQELENIRRRKQELLADIQRLKDEIAEVANEIENLGST-EERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNNGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTV----ERFIAMNRGINDGGDLPEELLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEEWIKCIKAAI 375          
BLAST of Cytohesin vs. Ensembl Celegans
Match: grp-1 (GTP exchange factor for ARFs 1 [Source:UniProtKB/Swiss-Prot;Acc:P34512])

HSP 1 Score: 176.407 bits (446), Expect = 1.623e-50
Identity = 111/373 (29.76%), Postives = 201/373 (53.89%), Query Frame = 3
Query:  174 LNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPD-------NKYNSDISNIEKAGWLWKQGGR-----IKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKP-CFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQR 1250
            L ++ KR+ QL  +I+ L+ E  ++   +  +      + ++ H + +  G KKFN +P + +++L S+  + + P+A+A ++   + L+K A+G+ LG+ ++PF  + L  +       ++  + ++R +L  F LPGESQKI++I+  +A+ Y  QNPS + N ++ + + Y+ IM+NT LHNP  K +       E +I++           +  +  +++++           +PD          N  + + E+ GWL+KQ          + KKRWFVLSE  L+YF     +  KG+I L N+ IR   +  S+P  FEI+S  +  IK CK+++ G++++G H  YKI   + E+M SW++AI R
Sbjct:   19 LPKVRKRKAQLVDEIEALKNEVREVDEELDQV-YYTHPKSKEYH-KIVVNGRKKFNQDPWKALDWLASRNVVAKDPQALALWMKAGEGLSKSAIGEILGD-NRPFALETLDRFTKEHKLHDVPIVPALRQYLFSFRLPGESQKINRILEKFAEVYANQNPS-YGNADQAHTVAYSCIMVNTLLHNPNVKDKPSL----EKYIEMNEQLLEKGAITIEQLTEVYESVSVTQF-----KIPDEVSTSGKGTVNDILLHAEREGWLFKQSSNPLFSGALSWKKRWFVLSENCLYYFDQMTDKEPKGIITLANVGIR-KVEAPSRPFMFEIFSLSDGQIKACKTEQDGRLVEGRHSIYKICAVNDEDMRSWINAISR 377          
BLAST of Cytohesin vs. Ensembl Celegans
Match: agef-1 (Arf-1 Guanine nucleotide Exchange Factor homolog [Source:UniProtKB/TrEMBL;Acc:G5EFH7])

HSP 1 Score: 107.071 bits (266), Expect = 2.041e-24
Identity = 58/183 (31.69%), Postives = 102/183 (55.74%), Query Frame = 3
Query:  324 GTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLT-DKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP--SIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPL 863
            G + F+  P++G+++L     +      +A F+  ++ LNK  VGD+LG+ S  FN  V+  YI   DFS ++ + ++R FL  F LPGE+QKID+++  +A  Y + NP   IF + +  Y++ +++IML T LHN T K +      ++ +I +    N      +  ++ IF++I  N +
Sbjct:  520 GIQIFSEKPKKGLKFLQEHGFVGTDAVEVAEFMMKEERLNKTQVGDFLGD-SDEFNNSVMHAYIDFLDFSSIDILAALRMFLEKFRLPGEAQKIDRLMLKFASRYLDCNPRQGIFASADAAYVLAFSIIMLTTDLHNKTVKNKM----TKQGYINMNRGINEGGNIPVELLEAIFEDISKNEI 697          
BLAST of Cytohesin vs. Ensembl Celegans
Match: bris-1 (BRag/Iqsec/Schizo related Arf GEF family member [Source:UniProtKB/TrEMBL;Acc:U4PLL0])

HSP 1 Score: 94.3597 bits (233), Expect = 1.285e-20
Identity = 52/162 (32.10%), Postives = 95/162 (58.64%), Query Frame = 3
Query:  309 RNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP---SIFKNENET-YIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIK 779
            R  RI    FN  PE G++ L +   ++ +P ++A+ L   + L+K  +G+Y+G +  P++  VL+ + +L D   +E   ++R  +  F LP E++KID+II  +A +Y + NP   S ++   +T +++++A+IMLNT LH+P  K+       + DF+K
Sbjct:   83 RQYRIALNFFNKKPERGVQLLTAWGFVKNSPDSLASLLFGRRGLSKSMIGEYIGTLHSPYHSLVLKYFTALIDIRGLEVDVALRKAMQFFILPKEAEKIDRIIQAFALHYSKSNPKRTSHYRGGWDTIHLLSFAIIMLNTDLHSPNVKQRMT----QADFVK 240          
BLAST of Cytohesin vs. Ensembl Celegans
Match: bris-1 (BRag/Iqsec/Schizo related Arf GEF family member [Source:UniProtKB/TrEMBL;Acc:U4PLL0])

HSP 1 Score: 94.3597 bits (233), Expect = 1.288e-20
Identity = 52/162 (32.10%), Postives = 95/162 (58.64%), Query Frame = 3
Query:  309 RNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP---SIFKNENET-YIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIK 779
            R  RI    FN  PE G++ L +   ++ +P ++A+ L   + L+K  +G+Y+G +  P++  VL+ + +L D   +E   ++R  +  F LP E++KID+II  +A +Y + NP   S ++   +T +++++A+IMLNT LH+P  K+       + DF+K
Sbjct:   88 RQYRIALNFFNKKPERGVQLLTAWGFVKNSPDSLASLLFGRRGLSKSMIGEYIGTLHSPYHSLVLKYFTALIDIRGLEVDVALRKAMQFFILPKEAEKIDRIIQAFALHYSKSNPKRTSHYRGGWDTIHLLSFAIIMLNTDLHSPNVKQRMT----QADFVK 245          
BLAST of Cytohesin vs. Ensembl Celegans
Match: bris-1 (BRag/Iqsec/Schizo related Arf GEF family member [Source:UniProtKB/TrEMBL;Acc:U4PLL0])

HSP 1 Score: 94.7449 bits (234), Expect = 1.365e-20
Identity = 52/162 (32.10%), Postives = 95/162 (58.64%), Query Frame = 3
Query:  309 RNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP---SIFKNENET-YIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIK 779
            R  RI    FN  PE G++ L +   ++ +P ++A+ L   + L+K  +G+Y+G +  P++  VL+ + +L D   +E   ++R  +  F LP E++KID+II  +A +Y + NP   S ++   +T +++++A+IMLNT LH+P  K+       + DF+K
Sbjct:  226 RQYRIALNFFNKKPERGVQLLTAWGFVKNSPDSLASLLFGRRGLSKSMIGEYIGTLHSPYHSLVLKYFTALIDIRGLEVDVALRKAMQFFILPKEAEKIDRIIQAFALHYSKSNPKRTSHYRGGWDTIHLLSFAIIMLNTDLHSPNVKQRMT----QADFVK 383          
BLAST of Cytohesin vs. Ensembl Fly
Match: step (gene:FBgn0086779 transcript:FBtr0085910)

HSP 1 Score: 246.128 bits (627), Expect = 7.057e-77
Identity = 129/382 (33.77%), Postives = 230/382 (60.21%), Query Frame = 3
Query:  165 LVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS---NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNEN-EIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI------DLITQMK 1277
            L++L R   ++++L  +I+ +++E  ++ + M+ L    D +   +  + + IG KKFN +P++GIEYLV  + ++  P+ +A FL   + LNK A+GDYLG     FN DVL+ +++L DF+ +  + ++R FL  F LPGE+QKID+++  +A+ Y + NP IF N +  Y++++A+IMLNT LHNP+ K +       + FI +    N+        ++ ++++I++ P       +P +  N  +    N +K GWLWKQGGR K+ K+RWF+L++  L+YF +   +  +G+IPLEN+ +R   D+S   CFE+++    +IIK CK+   G++++G H  Y++   ++E+ + W+  + +SI      D++ Q K
Sbjct:   36 LIELRR---KKQELLLEIQQIKDELCEVVSEMEALDVPEDCK-HSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGE-KNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDK----PTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPF-----KIPQDDGNDLMHTFFNPDKEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRK 403          
BLAST of Cytohesin vs. Ensembl Fly
Match: step (gene:FBgn0086779 transcript:FBtr0332471)

HSP 1 Score: 243.432 bits (620), Expect = 1.061e-72
Identity = 126/369 (34.15%), Postives = 221/369 (59.89%), Query Frame = 3
Query:  204 LKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS---NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNEN-EIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI------DLITQMK 1277
            L+   K +++E  ++ + M+ L    D +   +  + + IG KKFN +P++GIEYLV  + ++  P+ +A FL   + LNK A+GDYLG  +  FN DVL+ +++L DF+ +  + ++R FL  F LPGE+QKID+++  +A+ Y + NP IF N +  Y++++A+IMLNT LHNP+ K +       + FI +    N+        ++ ++++I++ P       +P +  N  +    N +K GWLWKQGGR K+ K+RWF+L++  L+YF +   +  +G+IPLEN+ +R   D+S   CFE+++    +IIK CK+   G++++G H  Y++   ++E+ + W+  + +SI      D++ Q K
Sbjct:  363 LRRPSKQIKDELCEVVSEMEALDVPEDCK-HSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKND-FNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDK----PTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPF-----KIPQDDGNDLMHTFFNPDKEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRK 720          
BLAST of Cytohesin vs. Ensembl Fly
Match: step (gene:FBgn0086779 transcript:FBtr0301616)

HSP 1 Score: 243.432 bits (620), Expect = 1.061e-72
Identity = 126/369 (34.15%), Postives = 221/369 (59.89%), Query Frame = 3
Query:  204 LKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS---NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNEN-EIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI------DLITQMK 1277
            L+   K +++E  ++ + M+ L    D +   +  + + IG KKFN +P++GIEYLV  + ++  P+ +A FL   + LNK A+GDYLG  +  FN DVL+ +++L DF+ +  + ++R FL  F LPGE+QKID+++  +A+ Y + NP IF N +  Y++++A+IMLNT LHNP+ K +       + FI +    N+        ++ ++++I++ P       +P +  N  +    N +K GWLWKQGGR K+ K+RWF+L++  L+YF +   +  +G+IPLEN+ +R   D+S   CFE+++    +IIK CK+   G++++G H  Y++   ++E+ + W+  + +SI      D++ Q K
Sbjct:  363 LRRPSKQIKDELCEVVSEMEALDVPEDCK-HSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKND-FNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDK----PTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPF-----KIPQDDGNDLMHTFFNPDKEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRK 720          
BLAST of Cytohesin vs. Ensembl Fly
Match: step (gene:FBgn0086779 transcript:FBtr0301617)

HSP 1 Score: 243.432 bits (620), Expect = 1.061e-72
Identity = 126/369 (34.15%), Postives = 221/369 (59.89%), Query Frame = 3
Query:  204 LKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS---NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNEN-EIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI------DLITQMK 1277
            L+   K +++E  ++ + M+ L    D +   +  + + IG KKFN +P++GIEYLV  + ++  P+ +A FL   + LNK A+GDYLG  +  FN DVL+ +++L DF+ +  + ++R FL  F LPGE+QKID+++  +A+ Y + NP IF N +  Y++++A+IMLNT LHNP+ K +       + FI +    N+        ++ ++++I++ P       +P +  N  +    N +K GWLWKQGGR K+ K+RWF+L++  L+YF +   +  +G+IPLEN+ +R   D+S   CFE+++    +IIK CK+   G++++G H  Y++   ++E+ + W+  + +SI      D++ Q K
Sbjct:  363 LRRPSKQIKDELCEVVSEMEALDVPEDCK-HSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDVAHFLYKGEGLNKTAIGDYLGEKND-FNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMETFAQRYCQLNPDIFTNTDTCYVLSFAIIMLNTSLHNPSVKDK----PTVDQFISMNRGINNGGDLPRGLLESLYESIRTEPF-----KIPQDDGNDLMHTFFNPDKEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEPRGIIPLENISVREIHDRSKPHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDILVQRK 720          
BLAST of Cytohesin vs. Ensembl Fly
Match: siz (gene:FBgn0026179 transcript:FBtr0078289)

HSP 1 Score: 116.316 bits (290), Expect = 2.802e-27
Identity = 63/187 (33.69%), Postives = 107/187 (57.22%), Query Frame = 3
Query:  309 RNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSI---FKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSN 857
            R  R+G   FN  PE+GI YL+ +  ++ TP+ +A FL T K L+++ +G+YLGN+   FN  VL  +    D S  +   ++R F + F +PGE+QKI++++ ++++ Y E N  I    ++ +  +++ +A+IMLNT LH P  K E     R EDFIK +   +     +   +  I+  +KS+
Sbjct:  768 RQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPER--RMRVEDFIKNLRGIDDCHDIDKDMLMGIYDRVKSD 952          
BLAST of Cytohesin vs. Ensembl Zebrafish
Match: cyth1a (cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657])

HSP 1 Score: 250.366 bits (638), Expect = 1.484e-78
Identity = 128/369 (34.69%), Postives = 226/369 (61.25%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++L+    +Q+TP+ IA FL   + LNK  +GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++++IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   20 ELSNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCVGESKT-TQRNKQIAMGRKKFNMDPKKGIQFLLENDLLQQTPEDIAQFLYKGEGLNKTVIGDYLGERDE-FNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPAV----ERFISMNRGINDGGDLPEELLRNLYESIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 376          
BLAST of Cytohesin vs. Ensembl Zebrafish
Match: cyth1a (cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657])

HSP 1 Score: 250.366 bits (638), Expect = 1.484e-78
Identity = 128/369 (34.69%), Postives = 226/369 (61.25%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++L+    +Q+TP+ IA FL   + LNK  +GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++++IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   20 ELSNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCVGESKT-TQRNKQIAMGRKKFNMDPKKGIQFLLENDLLQQTPEDIAQFLYKGEGLNKTVIGDYLGERDE-FNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPAV----ERFISMNRGINDGGDLPEELLRNLYESIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 376          
BLAST of Cytohesin vs. Ensembl Zebrafish
Match: cyth1a (cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657])

HSP 1 Score: 249.98 bits (637), Expect = 1.871e-78
Identity = 128/369 (34.69%), Postives = 226/369 (61.25%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++L+    +Q+TP+ IA FL   + LNK  +GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++++IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   18 ELSNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCVGESKT-TQRNKQIAMGRKKFNMDPKKGIQFLLENDLLQQTPEDIAQFLYKGEGLNKTVIGDYLGERDE-FNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPAV----ERFISMNRGINDGGDLPEELLRNLYESIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 374          
BLAST of Cytohesin vs. Ensembl Zebrafish
Match: cyth1a (cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657])

HSP 1 Score: 249.98 bits (637), Expect = 1.871e-78
Identity = 128/369 (34.69%), Postives = 226/369 (61.25%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++L+    +Q+TP+ IA FL   + LNK  +GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++++IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   18 ELSNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCVGESKT-TQRNKQIAMGRKKFNMDPKKGIQFLLENDLLQQTPEDIAQFLYKGEGLNKTVIGDYLGERDE-FNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPAV----ERFISMNRGINDGGDLPEELLRNLYESIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 374          
BLAST of Cytohesin vs. Ensembl Zebrafish
Match: cyth1b (cytohesin 1b [Source:ZFIN;Acc:ZDB-GENE-030131-4311])

HSP 1 Score: 248.44 bits (633), Expect = 8.510e-78
Identity = 131/386 (33.94%), Postives = 232/386 (60.10%), Query Frame = 3
Query:  135 MNQKHFTTDDLV-----KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            M   ++  DDL      +L  I +R+++L  DI+ L++E   +T  ++ LG   + RI    ++ + +G KKFN +P++GI++L+  + ++ T + IA FL   + LNK A+GDYLG   + FN  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE++   N++++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ +I
Sbjct:    1 MEADNYVPDDLTPEEKQELENIRRRKQELLEDIQRLKDEITKVTNEIECLGSTQE-RINMQRSKQMAMGRKKFNMDPKKGIQFLIENELLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSA----ERFICMNRGINDGGDLPEDLLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTTEEKEDWIKSIKSAI 374          
BLAST of Cytohesin vs. Ensembl Xenopus
Match: cyth2 (cytohesin 2 [Source:NCBI gene;Acc:448569])

HSP 1 Score: 244.202 bits (622), Expect = 4.690e-76
Identity = 130/376 (34.57%), Postives = 224/376 (59.57%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++T  ++ LG   + R     ++ + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG      N  VL  ++ L +F ++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  YI+++A+IMLNT LHNP  K +       E FI +    N+        ++ ++ +IK  P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   S EE + WM  I+ +I
Sbjct:   10 LTPEEQQELKNIQRRKQELLADIQRLKEEIAEVTNEIENLGST-EERKNLQKSKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCENIAQFLYKGEGLNKTAIGDYLGE-RDDLNIRVLHAFVELHEFMDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFESTDTCYILSFAIIMLNTSLHNPNVKDKPSV----ERFIAMNRGINNGGDLSEDLLRNLYDSIKHEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKMNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAASCEEKDEWMKCIRAAI 373          
BLAST of Cytohesin vs. Ensembl Xenopus
Match: cyth2 (cytohesin 2 [Source:NCBI gene;Acc:448569])

HSP 1 Score: 244.202 bits (622), Expect = 5.239e-76
Identity = 130/376 (34.57%), Postives = 224/376 (59.57%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++T  ++ LG   + R     ++ + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG      N  VL  ++ L +F ++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  YI+++A+IMLNT LHNP  K +       E FI +    N+        ++ ++ +IK  P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   S EE + WM  I+ +I
Sbjct:    9 LTPEEQQELKNIQRRKQELLADIQRLKEEIAEVTNEIENLGST-EERKNLQKSKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCENIAQFLYKGEGLNKTAIGDYLGE-RDDLNIRVLHAFVELHEFMDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFESTDTCYILSFAIIMLNTSLHNPNVKDKPSV----ERFIAMNRGINNGGDLSEDLLRNLYDSIKHEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKMNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAASCEEKDEWMKCIRAAI 372          
BLAST of Cytohesin vs. Ensembl Xenopus
Match: cyth2 (cytohesin 2 [Source:NCBI gene;Acc:448569])

HSP 1 Score: 243.817 bits (621), Expect = 5.627e-76
Identity = 130/376 (34.57%), Postives = 224/376 (59.57%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++T  ++ LG   + R     ++ + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG      N  VL  ++ L +F ++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  YI+++A+IMLNT LHNP  K +       E FI +    N+        ++ ++ +IK  P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   S EE + WM  I+ +I
Sbjct:    7 LTPEEQQELKNIQRRKQELLADIQRLKEEIAEVTNEIENLGST-EERKNLQKSKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCENIAQFLYKGEGLNKTAIGDYLGE-RDDLNIRVLHAFVELHEFMDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFESTDTCYILSFAIIMLNTSLHNPNVKDKPSV----ERFIAMNRGINNGGDLSEDLLRNLYDSIKHEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKMNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAASCEEKDEWMKCIRAAI 370          
BLAST of Cytohesin vs. Ensembl Xenopus
Match: cyth2 (cytohesin 2 [Source:NCBI gene;Acc:448569])

HSP 1 Score: 243.817 bits (621), Expect = 6.083e-76
Identity = 130/376 (34.57%), Postives = 224/376 (59.57%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++T  ++ LG   + R     ++ + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG      N  VL  ++ L +F ++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  YI+++A+IMLNT LHNP  K +       E FI +    N+        ++ ++ +IK  P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   S EE + WM  I+ +I
Sbjct:   12 LTPEEQQELKNIQRRKQELLADIQRLKEEIAEVTNEIENLGST-EERKNLQKSKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCENIAQFLYKGEGLNKTAIGDYLGE-RDDLNIRVLHAFVELHEFMDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFESTDTCYILSFAIIMLNTSLHNPNVKDKPSV----ERFIAMNRGINNGGDLSEDLLRNLYDSIKHEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKMNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAASCEEKDEWMKCIRAAI 375          
BLAST of Cytohesin vs. Ensembl Xenopus
Match: cyth2 (cytohesin 2 [Source:NCBI gene;Acc:448569])

HSP 1 Score: 244.202 bits (622), Expect = 6.281e-76
Identity = 130/376 (34.57%), Postives = 224/376 (59.57%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++T  ++ LG   + R     ++ + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG      N  VL  ++ L +F ++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  YI+++A+IMLNT LHNP  K +       E FI +    N+        ++ ++ +IK  P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   S EE + WM  I+ +I
Sbjct:   23 LTPEEQQELKNIQRRKQELLADIQRLKEEIAEVTNEIENLGST-EERKNLQKSKQVAMGRKKFNMDPKKGIQFLIENDLLKNTCENIAQFLYKGEGLNKTAIGDYLGE-RDDLNIRVLHAFVELHEFMDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFESTDTCYILSFAIIMLNTSLHNPNVKDKPSV----ERFIAMNRGINNGGDLSEDLLRNLYDSIKHEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKMNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAASCEEKDEWMKCIRAAI 386          
BLAST of Cytohesin vs. Ensembl Mouse
Match: Cyth2 (cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255])

HSP 1 Score: 247.284 bits (630), Expect = 2.258e-77
Identity = 128/378 (33.86%), Postives = 227/378 (60.05%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 376          
BLAST of Cytohesin vs. Ensembl Mouse
Match: Cyth2 (cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255])

HSP 1 Score: 244.973 bits (624), Expect = 1.297e-76
Identity = 127/372 (34.14%), Postives = 224/372 (60.22%), Query Frame = 3
Query:  168 VKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
            ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:    1 MELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG----LERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 360          
BLAST of Cytohesin vs. Ensembl Mouse
Match: Cyth2 (cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255])

HSP 1 Score: 243.432 bits (620), Expect = 7.372e-76
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLAGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. Ensembl Mouse
Match: Cyth3 (cytohesin 3 [Source:MGI Symbol;Acc:MGI:1335107])

HSP 1 Score: 240.736 bits (613), Expect = 7.619e-75
Identity = 126/365 (34.52%), Postives = 217/365 (59.45%), Query Frame = 3
Query:  183 IYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            I +R+K+L  DI+ L+ E  ++ T +  L  + + +      + + +G KKFN +P++GI++L+    +Q +P+ +A FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y   NP +F++ +  Y++++A+IMLNT LHN   + +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  S++ ++IK CK++  G++++G+H  Y+I   S EE E WM +I+ SI
Sbjct:   27 IRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTT-QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTA----ERFITMNRGINEGGDLPEELLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379          
BLAST of Cytohesin vs. Ensembl Mouse
Match: Cyth1 (cytohesin 1 [Source:MGI Symbol;Acc:MGI:1334257])

HSP 1 Score: 240.35 bits (612), Expect = 1.058e-74
Identity = 126/376 (33.51%), Postives = 226/376 (60.11%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L +DI+ L+EE  ++   +++LG   + R      + + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG   + F+  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + N  +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y   N++++IK CK++  G++++G+H  Y+I   + EE E W+  I+ +I
Sbjct:   12 LTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGST-EERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDE-FSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTV----ERFIAMNRGINDGGDLPEELLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAI 375          
BLAST of Cytohesin vs. UniProt/SwissProt
Match: sp|Q76MY7|CYH2_CHLAE (Cytohesin-2 OS=Chlorocebus aethiops OX=9534 GN=CYTH2 PE=2 SV=1)

HSP 1 Score: 247.669 bits (631), Expect = 1.530e-76
Identity = 128/378 (33.86%), Postives = 227/378 (60.05%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEELLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 376          
BLAST of Cytohesin vs. UniProt/SwissProt
Match: sp|P63034|CYH2_MOUSE (Cytohesin-2 OS=Mus musculus OX=10090 GN=Cyth2 PE=1 SV=2)

HSP 1 Score: 243.432 bits (620), Expect = 5.157e-75
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGL----ERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLAGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. UniProt/SwissProt
Match: sp|P63035|CYH2_RAT (Cytohesin-2 OS=Rattus norvegicus OX=10116 GN=Cyth2 PE=1 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 8.526e-75
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG----LERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. UniProt/SwissProt
Match: sp|Q99418|CYH2_HUMAN (Cytohesin-2 OS=Homo sapiens OX=9606 GN=CYTH2 PE=1 SV=2)

HSP 1 Score: 243.047 bits (619), Expect = 8.899e-75
Identity = 128/379 (33.77%), Postives = 227/379 (59.89%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             T ++ ++L  I +R+++L  +I+ L EE  +  + ++ L    +G       R + +G KKFN +P++GI++LV  + +Q TP+ IA FL   + LNK A+GDYLG   +  N  VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++AVIMLNT LHNP  + + G     E F+ +    N         ++ ++ +I++ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N+ ++IK CK++  G++++G+H  Y+I   +QEE + W+ +IQ ++ +
Sbjct:   11 LTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPG----LERFVAMNRGINEGGDLPEELLRNLYDSIRNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSV 377          
BLAST of Cytohesin vs. UniProt/SwissProt
Match: sp|O08967|CYH3_MOUSE (Cytohesin-3 OS=Mus musculus OX=10090 GN=Cyth3 PE=1 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 5.330e-74
Identity = 126/365 (34.52%), Postives = 217/365 (59.45%), Query Frame = 3
Query:  183 IYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            I +R+K+L  DI+ L+ E  ++ T +  L  + + +      + + +G KKFN +P++GI++L+    +Q +P+ +A FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y   NP +F++ +  Y++++A+IMLNT LHN   + +       E FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  S++ ++IK CK++  G++++G+H  Y+I   S EE E WM +I+ SI
Sbjct:   27 IRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTT-QRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTA----ERFITMNRGINEGGDLPEELLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASI 379          
BLAST of Cytohesin vs. TrEMBL
Match: A0A504Z1H1 (Cytohesin-2 OS=Fasciola gigantica OX=46835 GN=FGIG_06597 PE=4 SV=1)

HSP 1 Score: 280.411 bits (716), Expect = 2.959e-86
Identity = 147/396 (37.12%), Postives = 241/396 (60.86%), Query Frame = 3
Query:  135 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDK--SLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYN-SDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPN-SQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQII------KGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEI 1292
            M  +  T ++  +L  I +++ Q+   I+ L+ E +DIT +++ LG  +D   ED   R   IG K+FN + ++G++YL   K ++ TP+A+A F  ++   L+K AVG +LG + K FN  VL  + +L +F + +F+ ++R FL  F LPGESQKID+I++ +A+ Y   NP+IFK+ +E Y++ YAVI+LNT LHN  AK +N G   E+ F++ M +++  T+     V+R++  IK+ P+    +   D+ +N S+ SN    GWL K GGR+K+ K+RWFVL+E SL Y++ P+ S+  KG+IPLE L IR++ D++    FE+YS+ NE+IK  K+ + G          GHH  Y++   S  E ++W+  ++     I + + V+ I
Sbjct:    1 MECEELTAEEKERLKYITQQKLQVMKHIESLKIELHDITNQIENLGFPLD--CEDPQMRRRIIGCKEFNADTKQGLDYLFENKVVERTPEAVARFFIEEKDRLSKFAVGTFLGEVRKEFNMQVLDAFTNLHNFRDQDFLQALRRFLLSFQLPGESQKIDRILTSFAERYVSHNPAIFKSPHEAYVLAYAVILLNTTLHNANAKGQNFGLADEKTFVRTMLDYDDQTELSEDLVRRVYHEIKAEPI----RPASDDGFNGSNQSNAIMRGWLMKLGGRVKSWKRRWFVLTEDSLIYYLTPDRSRHCKGVIPLEGLNIRITQDRTKDHTFELYSSRNELIKASKADREGTTTPVPHREPGHHTVYRLAAPSSAERDNWIRMLESITHRIAEHRGVRSI 390          
BLAST of Cytohesin vs. TrEMBL
Match: A0A4E0RBH9 (Cytohesin-2 OS=Fasciola hepatica OX=6192 GN=D915_005803 PE=4 SV=1)

HSP 1 Score: 280.026 bits (715), Expect = 4.129e-86
Identity = 147/396 (37.12%), Postives = 240/396 (60.61%), Query Frame = 3
Query:  135 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDK--SLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYN-SDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPN-SQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQII------KGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEI 1292
            M  +  T ++  +L  I +++ Q+   I+ L+ E +DIT +++ LG  +D   ED   R   IG K+FN + ++G++YL   K ++ TP+A+A F  ++   L+K AVG +LG + K FN  VL  + +L +F + +F+ ++R FL  F LPGESQKID+I++ +A+ Y   NP+IFK+ +E Y++ YAVI+LNT LHN  AK +N G   E+ F++ M +++  T+     V+R++  IK+ P+    +   D+  N S+ SN    GWL K GGR+K+ K+RWFVL+E SL Y++ P+ S+  KG+IPLE L IR++ D++    FE+YS+ NE+IK  K+ + G          GHH  Y++   S  E ++W+  ++     I + + V+ I
Sbjct:    1 MECEELTAEEKERLKYITQQKLQVMKHIESLKIELHDITNQIENLGFPLD--CEDPQMRRRIIGCKEFNADTKQGLDYLFENKVVERTPEAVARFFIEEKDRLSKFAVGTFLGEVRKEFNMQVLDAFTNLHNFRDQDFLQALRRFLLSFQLPGESQKIDRILTSFAERYVSHNPAIFKSPHEAYVLAYAVILLNTTLHNANAKGQNFGLADEKTFVRTMLDYDDQTELSEDLVRRVYHEIKAEPI----RPASDDGLNGSNQSNAIMRGWLMKLGGRVKSWKRRWFVLTEDSLIYYLTPDRSRHCKGVIPLEGLNIRITQDRTKDHTFELYSSRNELIKASKADREGTTTPVPHREPGHHTVYRLAAPSSAERDNWIRMLESITHRIAEHRAVRSI 390          
BLAST of Cytohesin vs. TrEMBL
Match: A0A4Z2DPZ7 (Cytohesin-1 OS=Schistosoma japonicum OX=6182 GN=EWB00_010173 PE=3 SV=1)

HSP 1 Score: 283.493 bits (724), Expect = 1.242e-85
Identity = 144/389 (37.02%), Postives = 237/389 (60.93%), Query Frame = 3
Query:  135 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKS--LNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPN-SQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEI 1292
            M+    T ++  +L  I +++ Q+  +I+ L+ E  DIT +++ LG  +DG  EDS  R L +G KKFN+NP++G+EYL  +  I  +P  +A F  D++  L+K A+G Y+G + K FN  VL  +  L +F + EF+ ++R FL  F LPGESQKID+I++ +++ Y EQNP++F + +E Y+++YAVI+LNT LHN  AK  + G   E+ F++ M  F+ +T      +++I+  IK+ PL  +   L  +   S  +N    GWLWK GGR+K+ K+RWF+L+E SL Y++ P+ S+  KG I LE + IR+  DK+ + CFE+Y   N+++K CK ++      GHH  Y++   +  E + W+  ++R    + + +  + I
Sbjct:    1 MDYDDLTIEEKERLQFIRQQKTQVMKNIESLKLELSDITNQIENLGFSVDG--EDSSVRRLALGCKKFNNNPKQGLEYLFDQNIIGRSPDEVAKFFIDQNDNLSKHAIGTYIGEVRKEFNMQVLDAFAKLHNFKDEEFLPALRQFLFSFQLPGESQKIDRILTSFSERYVEQNPTVFNSPHEAYVLSYAVILLNTTLHNSNAKSHSLGLAEEKTFVRTMVEFDEETNLSEDLIRKIYHAIKNEPLRAVSDDL--SVCGSTQNNAVHKGWLWKLGGRVKSWKRRWFILTEDSLLYYLTPDRSRQTKGTIHLEGINIRLIHDKTKEYCFELYCPRNQLVKSCKIERD--FSAGHHTVYRMAAPTLIERDEWIRMLERVTHRLAERRGTRSI 383          
BLAST of Cytohesin vs. TrEMBL
Match: A0A419Q6U6 (Cytohesin-1 (Fragment) OS=Clonorchis sinensis OX=79923 GN=Cyth1 PE=4 SV=1)

HSP 1 Score: 276.944 bits (707), Expect = 3.281e-85
Identity = 132/369 (35.77%), Postives = 230/369 (62.33%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDK--SLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQ-SLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQ 1247
             T D+  KL  + +++ Q+  +I+ ++ E Y++T+++++ G  +D   ED   R   +G ++FN+NP++G+EYL  +  ++  P ++A F  ++   L+K  +G YLG + K FN +VL  +  L DF   EF+ S+R FL  F LPGESQKID+I++ +A++Y EQNP++F++ +E Y++ YA I+LNT LHN  AK +  G   E+ F++ + +++ +T      ++R++++IK+ P+        D    S    +   GWL K GGR+K+ K+RWFVL+E SL Y+  P+ Q ++KG+IPL+ L IR+S +++ +  FE++S  NE+IK  K+ K G    GHH +Y++   +  E + W+  ++
Sbjct:    1 LTLDETEKLKALRRQKIQVIKNIEAIKSELYEVTSQIESFGFPVD--CEDPAERRRILGCQEFNNNPKQGLEYLFEQGLLERNPTSVARFFVEEHERLSKVVLGTYLGEVRKEFNMEVLDAFTRLHDFRNQEFLPSLRHFLLSFQLPGESQKIDRILTSFAEWYLEQNPTMFRSPHEAYVLAYAAILLNTTLHNTNAKSQTLGLADEKVFVRTLLDYDRETDLPEDLIRRVYQDIKNEPIRAASDDGLDGI--SQNGKVLMKGWLLKLGGRVKSWKRRWFVLTENSLVYYTTPDRQRNVKGVIPLDGLNIRLSQERTKENSFELFSIRNEVIKASKADKDGSSAPGHHTTYRLAAATTAERDRWIRMLE 365          
BLAST of Cytohesin vs. TrEMBL
Match: A0A4S2LM98 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007748 PE=4 SV=1)

HSP 1 Score: 275.018 bits (702), Expect = 2.695e-84
Identity = 137/410 (33.41%), Postives = 241/410 (58.78%), Query Frame = 3
Query:  132 TMNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDK--SLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNS-QSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEIE*KFIFDHFILCISCYISIN 1352
             M     T D+  KL  + +++ Q+  +I+ ++ E Y++T+++++ G  +D   ED   R   +G ++FN+NP++G+EYL  +  ++  P ++A F  ++   L+K  +G YLG + K FN +VL  +  L DF   EF+ S+R FL  F LPGESQKID+I++ +A++Y EQNP++F++ +E Y++ YA I+LNT LHN  AK +  G   E+ F++ + +++ +T      +++++++IK+ P+        D    S    +   GWL K GGR+K+ K+RWFVL+E SL Y+  P+  +++KG+IPL+ L IR+S +++ +  FE++S  NE+IK  K+ K G    GHH +Y++   +  E + W+  ++     I + +  +           + C S   SIN
Sbjct:    2 VMEYDELTLDETEKLKALRRQKIQVIKNIEAIKSELYEVTSQIESFGFPVD--CEDPAERRRILGCQEFNNNPKQGLEYLFEQGLLERNPASVARFFVEEHERLSKVVLGTYLGEVRKEFNMEVLDAFTRLHDFRNQEFLPSLRHFLLSFQLPGESQKIDRILTSFAEWYLEQNPTMFRSPHEAYVLAYAAILLNTTLHNTNAKSQTLGLADEKVFVRTLLDYDRETDLPEDLIRKVYQDIKNEPIRAASDDGLDGI--SQNGKVVMKGWLLKLGGRVKSWKRRWFVLTENSLIYYTTPDRHRNVKGVIPLDGLNIRLSQERTKENSFELFSIRNEVIKASKADKDGSSAPGHHTTYRLAAATTAERDRWIRMLESVTHKIAERRGARSTS--------VDCTSGTGSIN 399          
BLAST of Cytohesin vs. Ensembl Cavefish
Match: cyth3a (cytohesin 3 [Source:NCBI gene;Acc:103025488])

HSP 1 Score: 246.899 bits (629), Expect = 2.385e-77
Identity = 130/376 (34.57%), Postives = 225/376 (59.84%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             + D+  +L  I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + IG KKFN +P++GI++L+    +Q TP  IA FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  YI+++++IMLNT LHNP  + +       + FI +    N         +K ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  S++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   11 LSLDERDELCNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCMGECKTS-QRNKQVAIGRKKFNMDPKKGIQFLLDNDLLQHTPDDIAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSSDTCYILSFSIIMLNTSLHNPNVRDKPSA----DRFISMNRGINEGGDLPEELLKNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 374          
BLAST of Cytohesin vs. Ensembl Cavefish
Match: cyth1b (cytohesin-1 [Source:NCBI gene;Acc:103022618])

HSP 1 Score: 245.743 bits (626), Expect = 7.290e-77
Identity = 130/386 (33.68%), Postives = 231/386 (59.84%), Query Frame = 3
Query:  135 MNQKHFTTDDLV-----KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            M +  +  DDL      +L  I +R+++L  DIK L++E  ++T  ++ LG   + R      + + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG   + FN +VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         +  ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE++   N++++IK CK++  G++++G+H  Y+I   + EE + W+++I+ +I
Sbjct:    1 MEEDTYVPDDLTPEEKQELENIRRRKQELLEDIKRLKDEIAEVTNEIENLGST-EERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTWEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIEVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSA----ERFIAMNRGINDGGDLPEDLLLNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTVEEKDEWINSIKAAI 374          
BLAST of Cytohesin vs. Ensembl Cavefish
Match: cyth1b (cytohesin-1 [Source:NCBI gene;Acc:103022618])

HSP 1 Score: 243.817 bits (621), Expect = 5.278e-76
Identity = 127/376 (33.78%), Postives = 228/376 (60.64%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L  DIK L++E  ++T  ++ LG   + R      + + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG   + FN +VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         +  ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE++   N++++IK CK++  G++++G+H  Y+I   + EE + W+++I+ +I
Sbjct:   14 LTPEEKQELENIRRRKQELLEDIKRLKDEIAEVTNEIENLGST-EERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTWEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIEVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSA----ERFIAMNRGINDGGDLPEDLLLNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTVEEKDEWINSIKAAI 377          
BLAST of Cytohesin vs. Ensembl Cavefish
Match: cyth1b (cytohesin-1 [Source:NCBI gene;Acc:103022618])

HSP 1 Score: 243.817 bits (621), Expect = 7.473e-76
Identity = 127/376 (33.78%), Postives = 228/376 (60.64%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L  DIK L++E  ++T  ++ LG   + R      + + +G KKFN +P++GI++L+    ++ T + IA FL   + LNK A+GDYLG   + FN +VL  ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y + NP +F++ +  Y++++A+IMLNT LHNP  K +       E FI +    N         +  ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE++   N++++IK CK++  G++++G+H  Y+I   + EE + W+++I+ +I
Sbjct:   31 LTPEEKQELENIRRRKQELLEDIKRLKDEIAEVTNEIENLGST-EERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENDLLKNTWEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIEVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPSA----ERFIAMNRGINDGGDLPEDLLLNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELFIPDNKDQVIKACKTEADGRVVEGNHTFYRISAPTVEEKDEWINSIKAAI 394          
BLAST of Cytohesin vs. Ensembl Cavefish
Match: si:dkey-283b15.4 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502])

HSP 1 Score: 239.195 bits (609), Expect = 1.981e-74
Identity = 126/373 (33.78%), Postives = 220/373 (58.98%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQ 1247
             + ++  +L  I +R+  L  +I+ L EE  +    ++ L    +G      +R++ +G KKFN +P++GI +LV  + ++ TP+ IA FL   + LNK A+GDYLG   + FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N  ++IK CK++  G++++G+H  Y+I   + EE + W+ +I+
Sbjct:   27 LSPEERSELEEIRRRKGALLLEIQRLREELREAIIEVEGLESSTEGSKTLQKSRHVAMGRKKFNMDPKKGIVFLVENELLRHTPEDIAQFLYKGEGLNKTAIGDYLGERDE-FNIRVLQAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCHCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPTV----ERFISMNRGINEGGDLPEELLRNLYDSIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYIPNNRGQLIKACKTEADGRVVEGNHMVYRISAPTPEEKDEWIHSIK 388          
BLAST of Cytohesin vs. Ensembl Sea Lamprey
Match: si:dkey-283b15.4 (cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502])

HSP 1 Score: 218.394 bits (555), Expect = 6.697e-67
Identity = 124/382 (32.46%), Postives = 217/382 (56.81%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNE-----NETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
             T ++  +L  I +R+++L  DI+ L++E  D+ T + +L    + +I     + + +G KKFN +P++GI +L   + ++ TP+ IA FL   + LNK A+G+YLG     FN  VL  ++ L +F+ +  + ++R FL  F LPGE+QKID+++  +A  Y + N  +F++      +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IK+ P       +P++  N D++    N ++ GWL K  GG++K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D      FE++  +N+  +IK CK+   G++++G H  Y+I   S EE + W+  I+ SI
Sbjct:   14 LTEEEQEELASIRRRKQELVVDIQRLKDEISDVMTEIASLDNAEESKIV-QRNKQMSMGRKKFNMDPKKGIRFLTENELLKNTPEDIAQFLYKGEGLNKTAIGEYLGE-RDDFNIQVLHAFVELHEFANLNLVQALRQFLWSFRLPGEAQKIDRMMEAFATRYCQCNAGVFQSTGGVATDTCYVLSFAIIMLNTSLHNPNVRDK----PTTERFILMNRGINDGGDLPEELLRNLYDSIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLVGGKVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPKKPNSFELFLPNNKGGVIKACKTDTDGRVVEGKHMVYRISAPSPEEKDEWIKCIKASI 383          
BLAST of Cytohesin vs. Ensembl Sea Lamprey
Match: iqsec1b (IQ motif and Sec7 domain ArfGEF 1b [Source:ZFIN;Acc:ZDB-GENE-120813-1])

HSP 1 Score: 115.161 bits (287), Expect = 1.092e-27
Identity = 62/210 (29.52%), Postives = 116/210 (55.24%), Query Frame = 3
Query:  309 RNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTD-KSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSI---FKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEK 926
            R  RIG   FN  PE+G+ YL+ +  + +TP  +A FL   K L+++ +G++LGN  + FN DVL   +   DFS ME  +++R F +   + GE+QK++++I  +++ Y   NP +   F+N +  +I+ +A+++LNT +++P  K E     + +DF+K +   +         +  I++ I+   L     H+      + ++N+EK
Sbjct:  461 RQYRIGLNLFNKKPEKGVAYLMERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQRAFNRDVLDCVVDEMDFSGMELDEALRMFQAHIRVQGEAQKVERLIEAFSQRYCMCNPGVVKNFQNPDTIFILAFAIVLLNTDMYSPNVKPERK--MKLDDFVKNLRGVDDGADIPREILVGIYERIQRGELKTNDDHV------TQVANVEK 662          
BLAST of Cytohesin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001471.1 (pep scaffold:Pmarinus_7.0:GL477283:166775:173339:-1 gene:ENSPMAG00000001328.1 transcript:ENSPMAT00000001471.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.916 bits (263), Expect = 3.190e-27
Identity = 52/178 (29.21%), Postives = 106/178 (59.55%), Query Frame = 3
Query:  339 NHNPEEGIEYLVSKKAIQETPKAIATFLTD-KSLNKRAVGDYLGNISKPFNCDVLQE---YISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFK---NENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIK 851
            N  PE+G+ +LVS+  +  T  A A FL   K L+++ +G++LGN  +PFN DVL+    ++   DFS +E  +++R F +   L GE+QK+++++ ++++ Y   NP++     +E+  +++ +A+++LNT +++P+ + +     R +DFIK +   +        F+  I++ I+
Sbjct:    1 NRKPEKGLAFLVSRGFVGATASAAAHFLLQRKGLSRQMIGEFLGNRQRPFNRDVLEVSRCFVDEMDFSGLELDEALRLFQTHVRLQGEAQKVERLVEVFSRRYCACNPAVVSALCSEDTVFVLAFAIVLLNTDMYSPSVRHDRK--MRLDDFIKNLRGVDDGEDIPRDFLVGIYERIR 176          
BLAST of Cytohesin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004134.1 (pep scaffold:Pmarinus_7.0:GL477097:5536:63408:-1 gene:ENSPMAG00000003754.1 transcript:ENSPMAT00000004134.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 105.531 bits (262), Expect = 2.098e-24
Identity = 57/178 (32.02%), Postives = 97/178 (54.49%), Query Frame = 3
Query:  324 GTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHE--QNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNI 848
            G + FN  P+ GI++L  +  +  T + +A FL ++  L+   VGDYLG   K  N + +  Y+   DFS  +F+ ++R FL GF LPGE+QKID+++  +A  + E  Q  ++F + +  Y++ Y++IML T LH+   K +      +E +IK+    N        ++  I+  I
Sbjct:  544 GIELFNKKPKRGIQFLQEQNMLGTTTEDVAQFLHSENRLDSTQVGDYLGENDK-LNKETMYTYVDQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFCECNQGQTVFASADTAYVLAYSIIMLTTDLHSLQVKHKMS----KEQYIKMNRGINDSKDLPEEYLSSIYDEI 716          
BLAST of Cytohesin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004144.1 (pep scaffold:Pmarinus_7.0:GL477097:6043:63444:-1 gene:ENSPMAG00000003754.1 transcript:ENSPMAT00000004144.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 104.76 bits (260), Expect = 3.311e-24
Identity = 57/178 (32.02%), Postives = 97/178 (54.49%), Query Frame = 3
Query:  324 GTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHE--QNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNI 848
            G + FN  P+ GI++L  +  +  T + +A FL ++  L+   VGDYLG   K  N + +  Y+   DFS  +F+ ++R FL GF LPGE+QKID+++  +A  + E  Q  ++F + +  Y++ Y++IML T LH+   K +      +E +IK+    N        ++  I+  I
Sbjct:  497 GIELFNKKPKRGIQFLQEQNMLGTTTEDVAQFLHSENRLDSTQVGDYLGENDK-LNKETMYTYVDQMDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARFCECNQGQTVFASADTAYVLAYSIIMLTTDLHSLQVKHKMS----KEQYIKMNRGINDSKDLPEEYLSSIYDEI 669          
BLAST of Cytohesin vs. Ensembl Yeast
Match: SEC7 (Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors; involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles [Source:SGD;Acc:S000002577])

HSP 1 Score: 102.449 bits (254), Expect = 1.552e-23
Identity = 51/136 (37.50%), Postives = 86/136 (63.24%), Query Frame = 3
Query:  336 FNHNPEEGIEYLVSKKAIQE-TPKAIATFLTD-KSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAK 737
            FN+ P++ I  L+ K  +++ +P +IA +L + + L+  AVGDYLG      N  ++  ++  FDF+ M  +D++R FL  F LPGE QKID+ +  +A+ + +QNP +F   +  Y+++Y++IMLNT LH+   K
Sbjct:  838 FNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGE-GDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIK 972          
BLAST of Cytohesin vs. Ensembl Yeast
Match: GEA2 (Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA2 has a paralog, GEA1, that arose from the whole genome duplication [Source:SGD;Acc:S000000748])

HSP 1 Score: 93.2041 bits (230), Expect = 1.196e-20
Identity = 69/215 (32.09%), Postives = 112/215 (52.09%), Query Frame = 3
Query:  327 TKKFNHNPEEGIEYLVSKKAI-QETPKAIATFL--TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQ---NPS------------IFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISN 917
            T  FN  P++GI  L+ K  I  ++ K IA FL   +  +NK+ +G  L +   P    +L EYI LFDFS +   ++IR  L+ F LPGESQ+I++II  ++  Y E    +PS            +  + +  +I++Y++IMLNT LHNP   KE+  F   ED+   +    +   F   ++ RI+ +I+   ++   +H  + K+  D  N
Sbjct:  567 TNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCH---PDKVSLLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDNAEDDISTVQPDADSVFILSYSIIMLNTDLHNPQV-KEHMSF---EDYSGNLKGCCNHKDFPFWYLDRIYCSIRDKEIVMPEEHHGNEKWFEDAWN 774          
BLAST of Cytohesin vs. Ensembl Yeast
Match: GEA1 (Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs); involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; GEA1 has a paralog, GEA2, that arose from the whole genome duplication [Source:SGD;Acc:S000003792])

HSP 1 Score: 75.485 bits (184), Expect = 6.391e-15
Identity = 49/165 (29.70%), Postives = 86/165 (52.12%), Query Frame = 3
Query:  327 TKKFNHNPEEGIEYLVSKKAI-QETPKAIATFL--TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLW-AKYYHEQNPS------------------------IFKNENETYIMTYAVIMLNTCLHNPTAK 737
             + FN   ++GI+ L+ K  I  ++ + IA+FL   +  LNK+ +G  L +   P    +L+E+I LFDF  +   ++IR  L+ F LPGESQ+I++I+  + +KY  +Q+                          +  + +  ++++Y++IMLNT  HNP  K
Sbjct:  549 VETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCD---PKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVK 710          
BLAST of Cytohesin vs. Ensembl Nematostella
Match: EDO38004 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEA8])

HSP 1 Score: 227.254 bits (578), Expect = 3.116e-70
Identity = 130/371 (35.04%), Postives = 220/371 (59.30%), Query Frame = 3
Query:  174 LNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLT-DKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQG---GRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENE--IIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            L  I +++  L  +I+ L+ E  ++T+ +++L    D   ED   +  +IG KKF+ +P++GI+YLV    +  TP+ +A FL  ++ LNK  +G+YLG  +K FN DV  +++ L  F +M  + ++R FL  F LPGE+QKID+++  +A+ Y   NP +F + +  Y++++A+I+LNT LHNP  K +       E FI++    N     +  F+  ++ +IKS         +P++   SDI+    N ++ G L K+G   G  K+ +KR+F+L +  L+YF +   +  +G+IPLENL +R + D   K CFEIYS+EN   +IK CK+   G++++GHH  Y+I   S+EE ++W+  I+ S+
Sbjct:   15 LMSIRQKKSNLLQEIQQLKAEISEVTSELESLDHQ-DVTGEDPKMKQKQIGKKKFSMDPQKGIDYLVMHGLLNNTPEDLADFLLKEEGLNKTQIGNYLGE-NKEFNLDVFAKFVDLHKFKDMILVQALRQFLWSFRLPGEAQKIDRMMEAFAQKYCADNPGLFTSTDTCYVLSFAIILLNTSLHNPNVKDK----PTVEKFIQMNRGINCGEDLDRDFLVALYDSIKSEEF-----KIPEDD-GSDITHTFFNPDREGQLIKEGTSCGLHKSWRKRYFILKDNCLYYFKNAGDREPRGIIPLENLQVREANDAKRKYCFEIYSSENSTGLIKACKTDSEGKVVEGHHDVYRICASSEEERQTWIQCIKASM 373          
BLAST of Cytohesin vs. Ensembl Nematostella
Match: EDO29369 (pep supercontig:ASM20922v1:NEMVEscaffold_1160:24851:31523:-1 gene:NEMVEDRAFT_v1g144802 transcript:EDO29369 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 158.303 bits (399), Expect = 1.457e-45
Identity = 87/241 (36.10%), Postives = 143/241 (59.34%), Query Frame = 3
Query:  561 FLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQG---GRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENE--IIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            FL  F LPGE+QKID+++  +A+ Y   NP +F + +  Y++++A+I+LNT LHNP  K +       E FI++    N     +  F+  ++ +IKS         +P++   SDI+    N ++ G L K+G   G  K+ +KR+F+L +  L+YF +   +  +G+IPLENL +R + D   K CFEIYS+EN   +IK CK+   G++++GHH  Y+I   S+EE ++W+  I+ S+
Sbjct:    3 FLWSFRLPGEAQKIDRMMEAFAQKYCADNPGLFTSTDTCYVLSFAIILLNTSLHNPNVKDK----PTVEKFIQMNRGINCGEDLDRDFLVALYDSIKSEEF-----KIPEDD-GSDITHTFFNPDREGQLIKEGTSCGLHKSWRKRYFILKDNCLYYFKNAGDREPRGIIPLENLQVREANDAKRKYCFEIYSSENSTGLIKACKTDSEGKVVEGHHDVYRICASSEEERQTWIQCIKASM 233          
BLAST of Cytohesin vs. Ensembl Nematostella
Match: EDO34882 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN35])

HSP 1 Score: 127.487 bits (319), Expect = 4.583e-32
Identity = 67/184 (36.41%), Postives = 116/184 (63.04%), Query Frame = 3
Query:  315 LRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPS-IFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIM------GNFNSDTQFELSFVKRIFK 842
            +RIG  +FN  PE+G+ YL++ + I + P+A+A FL ++  ++K+ +G+YLGN+   FN  VL+ +   FDF+ ME   ++R FL+ F +PGE+QKI++++ ++A+ Y   NP+     +++  I+ +A++MLNT LH+P  KK       +EDFI+ +      GNF S++       +R+FK
Sbjct:   36 MRIGINQFNRKPEKGVTYLIAHQVIDDNPEAVAKFLLSEHGVSKQRLGEYLGNLQNDFNMAVLKCFAESFDFTGMEIDVALRTFLAQFRIPGEAQKIERLMEVFAEQYISCNPTDDTSAQDKVLILAFAIVMLNTDLHSPNVKKRM----TQEDFIRNLEGTNNGGNFPSESL--AGIYRRVFK 213          
BLAST of Cytohesin vs. Ensembl Nematostella
Match: EDO41902 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S350])

HSP 1 Score: 115.931 bits (289), Expect = 1.690e-27
Identity = 60/183 (32.79%), Postives = 107/183 (58.47%), Query Frame = 3
Query:  324 GTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP--SIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPL 863
            G  KFN NP++G+++L     +  +   +A FL  D+ L+K  +G+ +G+ +  F+  V+ EY+   DF++MEF+ S+R FL+ F LPGE+QKID+++  +A  Y + NP  S+F + +  Y++ Y++IML T LHNP  K++      +E +  +    N        +++ I+  I+ N +
Sbjct:  687 GIAKFNKNPKKGMKFLQENGLLGMSAGEVAEFLHGDERLDKMQIGELIGD-NDDFSKQVMYEYVDKLDFTDMEFVSSLRLFLTNFRLPGEAQKIDRLMEKFASRYFDTNPNNSVFASADAAYVLAYSIIMLTTDLHNPQVKRKI----TKEQYCSMNRGINDSKDLPQEYLEGIYDEIQHNEI 864          
BLAST of Cytohesin vs. Ensembl Nematostella
Match: EDO31538 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXN1])

HSP 1 Score: 103.219 bits (256), Expect = 2.368e-23
Identity = 57/187 (30.48%), Postives = 102/187 (54.55%), Query Frame = 3
Query:  315 LRIGTKKFNHNPEEGIEYLVSKKAIQE--TPKAIATFLTDK-SLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLL 866
            L+ G++ FN+ P++GIE+L     +     P+ +A  L +   L+K+ +G+Y+G   K  N  VL  ++  F+F ++   + +R FL  F LPGES  I+ I+  +++ + E NP ++ N++  + + YAVIMLN   HN   K++       EDF + +   N    F  + ++ IF  IK+  ++
Sbjct:  680 LQAGSEHFNNKPKKGIEFLQEHGLLHTPLDPEEMARLLRENPRLDKKTIGEYIG---KKDNSKVLDAFVRSFEFHDLRVDEGLRQFLESFRLPGESPVIEHIMEFFSEVFFECNPEVYANKDAVFTLAYAVIMLNVDQHNANIKQQKPMV--LEDFKRNLRKINGGNDFPATMLEEIFTCIKNEEIV 861          
BLAST of Cytohesin vs. Ensembl Medaka
Match: CYTH3 (cytohesin-3 [Source:NCBI gene;Acc:101158948])

HSP 1 Score: 249.21 bits (635), Expect = 3.483e-78
Identity = 131/370 (35.41%), Postives = 226/370 (61.08%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKP-CFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++L+    +Q TP+ IA FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D+  KP CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:   18 ELSNIRRRKKELLDDIERLKFEIAEVMTEIEQLTCVGESKTT-QRNKQIAMGRKKFNMDPKKGIQFLLENDLLQNTPEDIAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPPV----ERFISMNRGINEGGDLPEDLLRNLYDSIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIR-EVDEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTAEEKEEWIKSIKASI 374          
BLAST of Cytohesin vs. Ensembl Medaka
Match: ENSORLT00000004392.2 (cytohesin-3 [Source:NCBI gene;Acc:101174779])

HSP 1 Score: 241.121 bits (614), Expect = 3.953e-75
Identity = 127/386 (32.90%), Postives = 229/386 (59.33%), Query Frame = 3
Query:  135 MNQKHFTTDDLV-----KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            M++ +   +DL      +L+ I +R+++L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++++    +Q TP+ IA FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + N  +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:    1 MDEDNHVPEDLSLEERDELSNIRRRKRELLDDIERLKFEIAEVMTEIEQLTCVGESKT-SQRNKQVAMGRKKFNMDPKKGIQFMLENDLLQNTPEDIAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNAGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPPV----ERFISMNRGINEGGDLPEELLRNLYDSIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 374          
BLAST of Cytohesin vs. Ensembl Medaka
Match: CYTH3 (cytohesin-3 [Source:NCBI gene;Acc:101158948])

HSP 1 Score: 238.039 bits (606), Expect = 3.516e-74
Identity = 129/370 (34.86%), Postives = 220/370 (59.46%), Query Frame = 3
Query:  171 KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKP-CFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            +L+ I +R+K+L  DI        +++ R     C +D   +    + + +G KKFN +P++GI++L+    +Q TP+ IA FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + NP +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IKS P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D+  KP CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:    2 ELSNIRRRKKELLDDI--------EVSNRCNVFICKLDKTTQ--RNKQIAMGRKKFNMDPKKGIQFLLENDLLQNTPEDIAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPP----VERFISMNRGINEGGDLPEDLLRNLYDSIKSEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIR-EVDEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTAEEKEEWIKSIKASI 349          
BLAST of Cytohesin vs. Ensembl Medaka
Match: ENSORLT00000032174.1 (cytohesin-3 [Source:NCBI gene;Acc:101174779])

HSP 1 Score: 236.884 bits (603), Expect = 2.013e-73
Identity = 127/387 (32.82%), Postives = 229/387 (59.17%), Query Frame = 3
Query:  135 MNQKHFTTDDLV-----KLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWK-QGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSI 1256
            M++ +   +DL      +L+ I +R+++L  DI+ L+ E  ++ T ++ L C+ + +      + + +G KKFN +P++GI++++    +Q TP+ IA FL   + LNK  +GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A  Y + N  +F++ +  Y++++A+IMLNT LHNP  + +       E FI +    N         ++ ++ +IK+ P       +P++  N D++    N ++ GWL K  GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   +     CFE+Y  +++ ++IK CK++  G++++G+H  Y+I   + EE E W+ +I+ SI
Sbjct:    1 MDEDNHVPEDLSLEERDELSNIRRRKRELLDDIERLKFEIAEVMTEIEQLTCVGESKT-SQRNKQVAMGRKKFNMDPKKGIQFMLENDLLQNTPEDIAQFLYKGEGLNKTVIGDYLGE-RDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCQCNAGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPPV----ERFISMNRGINEGGDLPEELLRNLYDSIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPNHKGQVIKACKTEADGRVVEGNHVVYRISAPTPEEKEEWIKSIKASI 375          
BLAST of Cytohesin vs. Ensembl Medaka
Match: si:dkey-283b15.4 (cytohesin 2 [Source:NCBI gene;Acc:101160506])

HSP 1 Score: 235.728 bits (600), Expect = 1.080e-72
Identity = 125/378 (33.07%), Postives = 222/378 (58.73%), Query Frame = 3
Query:  150 FTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDIS----NIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIY--SNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDL 1262
             + ++  +L  I +R+  L  +I+ L EE  +    ++ L    +G      +R++ +G KKFN +P++GI +LV  + ++ T + IA FL   + LNK A+GDYLG     FN  VLQ ++ L +F+++  + ++R FL  F LPGE+QKID+++  +A+ Y   N  +F++ +  Y++++A+IMLNT LHNP   ++  G  R   FI +    N         ++ ++++IK+ P       +P++  N D++    N ++ GWL K GGR+K  K+RWF+L++  L+YF +   +  +G+IPLENL IR   D     CFE+Y  +N  ++IK CK++  G++++G+H  Y+I   + EE + W+ +I+ ++ +
Sbjct:   27 LSPEERSELEDIRRRKGILLQEIQRLREELREAILEVEGLETSTEGSKTLQKSRHVAMGRKKFNMDPKKGILFLVENELVRHTAEDIAQFLYKGEGLNKTAIGDYLGE-RDDFNIKVLQAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCHCNAGVFQSTDTCYVLSFAIIMLNTSLHNPNV-RDKPGLDR---FISMNRGINEGGDLPEDLLRNLYESIKNEPF-----KIPEDDGN-DLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYIPNNRGQLIKACKTEADGRVVEGNHMVYRISAPTPEEKDEWIHSIKSAVSV 393          
BLAST of Cytohesin vs. Planmine SMEST
Match: SMESG000053199.1 (SMESG000053199.1)

HSP 1 Score: 799.275 bits (2063), Expect = 0.000e+0
Identity = 386/387 (99.74%), Postives = 387/387 (100.00%), Query Frame = 3
Query:  135 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEIE 1295
            MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCD+SSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEIE
Sbjct:    1 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDRSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEIE 387          
BLAST of Cytohesin vs. Planmine SMEST
Match: SMESG000053199.1 (SMESG000053199.1)

HSP 1 Score: 233.417 bits (594), Expect = 5.825e-76
Identity = 112/115 (97.39%), Postives = 114/115 (99.13%), Query Frame = 3
Query:  135 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISK 479
            MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGN+ +
Sbjct:    1 MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNMKR 115          
BLAST of Cytohesin vs. Planmine SMEST
Match: SMESG000056462.1 (SMESG000056462.1)

HSP 1 Score: 241.506 bits (615), Expect = 1.711e-75
Identity = 132/375 (35.20%), Postives = 214/375 (57.07%), Query Frame = 3
Query:  162 DLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIIDGRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLL----CLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQSLKGMIPLENLLIRMSCDKSSKP-CFEIYSNENEIIKGCKSKKSGQIIKGHHYSYKIYCFSQEEMESWMDAIQRSIDLITQ 1271
            D  KL  I   +K+L  +I+ L+E+   +   M+  G I DG+I D   +   I    FN+ P+ GIE+L++ + I+ETP+ +A FL +  LNKR++GDYLG+I+  FN  VL  Y+ L DF   EF+D +R FLSGF LPGESQKI +II  W+ +Y+E NP +F N +E Y++ YAVIMLNT L+NP A  +N  FG+EE F+K M  +  +  F+   ++ ++  IK++PL+     +++  P NK N         G LW Q   ++  KKR FVL    L    + N+  ++  I L N+ +    + +++     ++S  N +I   K+ +     + +  +++  C S +E + W+ AI++ ++ I +
Sbjct:    4 DSKKLEIIRNARKKLMVEIESLKEQLKKVNDDMRNNGFIQDGKIVDPELKYRNIAKTHFNNKPKRGIEFLITNQIIKETPEDVAKFLQEPDLNKRSIGDYLGDITVEFNRKVLDAYVRLHDFRHKEFVDGLRVFLSGFFLPGESQKISEIIKAWSDFYYECNPKMFNNADEPYVLAYAVIMLNTTLNNPNAISQNIEFGKEEAFLKTMLEY-ENYSFQEDLLRNVYHTIKTDPLINFGNIVNELYPTNKMN---------GELWYQSNNLRVWKKRTFVLLPECLLILTNDNNPQVRYKIALTNVQVDRVFETTNRDFILNLHSRTNGVISATKTGRDNVEEQKNMRNFRFACNSSDEQKEWLKAIKQCLNKINE 368          
BLAST of Cytohesin vs. Planmine SMEST
Match: SMESG000041501.1 (SMESG000041501.1)

HSP 1 Score: 123.635 bits (309), Expect = 8.901e-30
Identity = 76/219 (34.70%), Postives = 126/219 (57.53%), Query Frame = 3
Query:  324 GTKKFNHNPEEGIEYLVSKKAIQETPKAIATFL-TDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNP--SIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGRIKNMK 971
            G   FN  P +G+ YL ++  +  + + +A FL  D  L+K A+GD+LG   K +N +V+  ++  F+F+E EF+ S+R FLSGF LPGE+QKID+++  +A  Y E NP  S FK+ +  Y++ Y++IML T LH+   K  N    R+E++IK+    N     ++ ++  I+  I  N +  + +   D K++S I N + +    KQ   + NM+
Sbjct:  612 GINLFNKKPLKGLNYLQNQTLLGTSVEDVAEFLHKDDRLDKTAIGDFLGENEK-YNIEVMYAFVDQFEFTEKEFVASLRDFLSGFRLPGEAQKIDRLMEKFAARYCECNPTNSQFKSADTAYVLAYSIIMLTTDLHSSQIKSRNR--MRKEEYIKMNRGINESGDLDIEYLGNIYDEIAGNEIK-IKESTVDKKHSSYIDNKQASIISEKQRKLLFNME 826          
BLAST of Cytohesin vs. Planmine SMEST
Match: SMESG000010938.1 (SMESG000010938.1)

HSP 1 Score: 108.612 bits (270), Expect = 8.649e-25
Identity = 69/217 (31.80%), Postives = 115/217 (53.00%), Query Frame = 3
Query:  315 LRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKSLNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLPGESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTAKKENGGFGREEDFIKIMGNFNSDTQF---ELSFVKRIFKNIKSNPLLCLHKHLPDNKYNSDISNIEKAGWLWKQGGR 956
            ++IGT+KFN++ ++GI+YL  +   Q   +  + F  +  LNK  +G+Y   I    N  V +EYI LF+F  +    +IR FL  F LPGE+  I  I+  +AK YH  NP +  + + T+++ YA++MLN   HNP +KK+      E+ F + +   N    +   E   + +I++ IK+  ++     +P     S+   I K  +LW+Q  R
Sbjct:  629 IKIGTEKFNNDIKDGIKYLREQGFCQTNQELASLFRENPRLNKTFIGEY---ICTRNNVGVREEYIKLFNFRGLRLDCAIRMFLDEFRLPGEAANIQLILECFAKAYHTSNPEMVSDPDSTFVLLYAIVMLNVDQHNPNSKKQQAPMTVEQ-FKRNLYEPNKKKYYGNVEEEVLNKIYEAIKTEEIV-----MP-----SEQRGIIKDNYLWRQLLR 831          
The following BLAST results are available for this feature:
BLAST of Cytohesin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CYTH23.185e-7733.86cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502][more]
CYTH21.170e-7533.77cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502][more]
CYTH21.853e-7533.77cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502][more]
CYTH31.041e-7434.52cytohesin 3 [Source:HGNC Symbol;Acc:HGNC:9504][more]
CYTH11.772e-7433.51cytohesin 1 [Source:HGNC Symbol;Acc:HGNC:9501][more]
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BLAST of Cytohesin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grp-11.623e-5029.76GTP exchange factor for ARFs 1 [Source:UniProtKB/... [more]
agef-12.041e-2431.69Arf-1 Guanine nucleotide Exchange Factor homolog ... [more]
bris-11.285e-2032.10BRag/Iqsec/Schizo related Arf GEF family member [... [more]
bris-11.288e-2032.10BRag/Iqsec/Schizo related Arf GEF family member [... [more]
bris-11.365e-2032.10BRag/Iqsec/Schizo related Arf GEF family member [... [more]
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BLAST of Cytohesin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
step7.057e-7733.77gene:FBgn0086779 transcript:FBtr0085910[more]
step1.061e-7234.15gene:FBgn0086779 transcript:FBtr0332471[more]
step1.061e-7234.15gene:FBgn0086779 transcript:FBtr0301616[more]
step1.061e-7234.15gene:FBgn0086779 transcript:FBtr0301617[more]
siz2.802e-2733.69gene:FBgn0026179 transcript:FBtr0078289[more]
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BLAST of Cytohesin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyth1a1.484e-7834.69cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657][more]
cyth1a1.484e-7834.69cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657][more]
cyth1a1.871e-7834.69cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657][more]
cyth1a1.871e-7834.69cytohesin 1a [Source:ZFIN;Acc:ZDB-GENE-030131-657][more]
cyth1b8.510e-7833.94cytohesin 1b [Source:ZFIN;Acc:ZDB-GENE-030131-4311... [more]
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BLAST of Cytohesin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyth24.690e-7634.57cytohesin 2 [Source:NCBI gene;Acc:448569][more]
cyth25.239e-7634.57cytohesin 2 [Source:NCBI gene;Acc:448569][more]
cyth25.627e-7634.57cytohesin 2 [Source:NCBI gene;Acc:448569][more]
cyth26.083e-7634.57cytohesin 2 [Source:NCBI gene;Acc:448569][more]
cyth26.281e-7634.57cytohesin 2 [Source:NCBI gene;Acc:448569][more]
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BLAST of Cytohesin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cyth22.258e-7733.86cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255][more]
Cyth21.297e-7634.14cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255][more]
Cyth27.372e-7633.77cytohesin 2 [Source:MGI Symbol;Acc:MGI:1334255][more]
Cyth37.619e-7534.52cytohesin 3 [Source:MGI Symbol;Acc:MGI:1335107][more]
Cyth11.058e-7433.51cytohesin 1 [Source:MGI Symbol;Acc:MGI:1334257][more]
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BLAST of Cytohesin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q76MY7|CYH2_CHLAE1.530e-7633.86Cytohesin-2 OS=Chlorocebus aethiops OX=9534 GN=CYT... [more]
sp|P63034|CYH2_MOUSE5.157e-7533.77Cytohesin-2 OS=Mus musculus OX=10090 GN=Cyth2 PE=1... [more]
sp|P63035|CYH2_RAT8.526e-7533.77Cytohesin-2 OS=Rattus norvegicus OX=10116 GN=Cyth2... [more]
sp|Q99418|CYH2_HUMAN8.899e-7533.77Cytohesin-2 OS=Homo sapiens OX=9606 GN=CYTH2 PE=1 ... [more]
sp|O08967|CYH3_MOUSE5.330e-7434.52Cytohesin-3 OS=Mus musculus OX=10090 GN=Cyth3 PE=1... [more]
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BLAST of Cytohesin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A504Z1H12.959e-8637.12Cytohesin-2 OS=Fasciola gigantica OX=46835 GN=FGIG... [more]
A0A4E0RBH94.129e-8637.12Cytohesin-2 OS=Fasciola hepatica OX=6192 GN=D915_0... [more]
A0A4Z2DPZ71.242e-8537.02Cytohesin-1 OS=Schistosoma japonicum OX=6182 GN=EW... [more]
A0A419Q6U63.281e-8535.77Cytohesin-1 (Fragment) OS=Clonorchis sinensis OX=7... [more]
A0A4S2LM982.695e-8433.41Uncharacterized protein OS=Opisthorchis felineus O... [more]
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BLAST of Cytohesin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyth3a2.385e-7734.57cytohesin 3 [Source:NCBI gene;Acc:103025488][more]
cyth1b7.290e-7733.68cytohesin-1 [Source:NCBI gene;Acc:103022618][more]
cyth1b5.278e-7633.78cytohesin-1 [Source:NCBI gene;Acc:103022618][more]
cyth1b7.473e-7633.78cytohesin-1 [Source:NCBI gene;Acc:103022618][more]
si:dkey-283b15.41.981e-7433.78cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502][more]
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BLAST of Cytohesin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:dkey-283b15.46.697e-6732.46cytohesin 2 [Source:HGNC Symbol;Acc:HGNC:9502][more]
iqsec1b1.092e-2729.52IQ motif and Sec7 domain ArfGEF 1b [Source:ZFIN;Ac... [more]
ENSPMAT00000001471.13.190e-2729.21pep scaffold:Pmarinus_7.0:GL477283:166775:173339:-... [more]
ENSPMAT00000004134.12.098e-2432.02pep scaffold:Pmarinus_7.0:GL477097:5536:63408:-1 g... [more]
ENSPMAT00000004144.13.311e-2432.02pep scaffold:Pmarinus_7.0:GL477097:6043:63444:-1 g... [more]
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BLAST of Cytohesin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
SEC71.552e-2337.50Guanine nucleotide exchange factor (GEF) for ADP r... [more]
GEA21.196e-2032.09Guanine nucleotide exchange factor for ADP ribosyl... [more]
GEA16.391e-1529.70Guanine nucleotide exchange factor for ADP ribosyl... [more]
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BLAST of Cytohesin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO380043.116e-7035.04Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO293691.457e-4536.10pep supercontig:ASM20922v1:NEMVEscaffold_1160:2485... [more]
EDO348824.583e-3236.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO419021.690e-2732.79Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315382.368e-2330.48Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cytohesin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CYTH33.483e-7835.41cytohesin-3 [Source:NCBI gene;Acc:101158948][more]
ENSORLT00000004392.23.953e-7532.90cytohesin-3 [Source:NCBI gene;Acc:101174779][more]
CYTH33.516e-7434.86cytohesin-3 [Source:NCBI gene;Acc:101158948][more]
ENSORLT00000032174.12.013e-7332.82cytohesin-3 [Source:NCBI gene;Acc:101174779][more]
si:dkey-283b15.41.080e-7233.07cytohesin 2 [Source:NCBI gene;Acc:101160506][more]
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BLAST of Cytohesin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000053199.10.000e+099.74SMESG000053199.1[more]
SMESG000053199.15.825e-7697.39SMESG000053199.1[more]
SMESG000056462.11.711e-7535.20SMESG000056462.1[more]
SMESG000041501.18.901e-3034.70SMESG000041501.1[more]
SMESG000010938.18.649e-2531.80SMESG000010938.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025418 ID=SMED30025418|Name=Cytohesin|organism=Schmidtea mediterranea sexual|type=transcript|length=1352bp
TTTGTTATAATAATGCAATTTAGATTAATTAAATGCTATTCTAATTCAAA
TATCTTACTGAAATAATATTTTATTTACAACGAAAATTAAATACAAGTTT
TTTTATCATATTGATTTTGAAAAGTTCTTCCACAATGAATCAGAAACACT
TTACCACAGATGACTTGGTAAAATTAAATCGAATTTATAAACGTCAAAAA
CAATTGAAAAGTGATATAAAGGATTTGGAAGAAGAATTTTATGATATTAC
TACAAGAATGAAAACGCTAGGATGCATAATCGATGGAAGAATAGAAGACT
CACATACGCGAAATTTGCGAATAGGAACGAAAAAATTTAATCACAACCCT
GAAGAAGGAATCGAATATTTGGTGTCAAAAAAAGCAATACAAGAAACACC
GAAAGCCATTGCAACTTTTTTAACTGACAAGTCCTTGAATAAGAGAGCGG
TTGGAGATTATTTGGGAAATATATCGAAACCATTCAACTGCGACGTTCTT
CAAGAATATATCAGTTTATTCGATTTCAGTGAAATGGAATTCATAGATTC
GATAAGATTCTTTCTCTCTGGATTCCATCTTCCAGGCGAAAGCCAAAAGA
TTGATAAAATCATCTCATTATGGGCAAAATATTATCATGAGCAAAATCCA
AGTATTTTCAAAAATGAGAACGAAACATATATTATGACCTATGCAGTCAT
CATGTTGAATACTTGTCTACACAATCCTACCGCTAAAAAGGAAAATGGAG
GCTTCGGTCGAGAGGAAGATTTTATAAAAATCATGGGAAATTTTAATTCA
GATACTCAATTTGAGTTATCTTTTGTAAAGAGAATTTTCAAAAATATAAA
ATCCAACCCCCTGTTATGTTTACATAAACATTTACCCGACAACAAATACA
ATTCCGATATTTCTAATATTGAAAAAGCTGGTTGGTTGTGGAAGCAAGGA
GGACGGATCAAGAATATGAAAAAGAGGTGGTTTGTTTTATCAGAATATTC
ACTATTCTACTTCATTCATCCCAATAGTCAATCATTGAAAGGAATGATTC
CGCTGGAAAACTTACTCATCCGTATGTCATGCGACAAGTCAAGCAAACCA
TGTTTTGAGATATATTCCAATGAGAATGAAATTATCAAAGGATGCAAAAG
CAAAAAGAGTGGCCAAATAATAAAGGGTCATCATTACAGCTATAAAATAT
ATTGTTTCTCCCAAGAGGAAATGGAATCGTGGATGGATGCCATTCAACGA
AGCATAGACTTGATTACACAGATGAAATTAGTGAAAGAAATTGAATAGAA
ATTTATTTTTGATCATTTTATTTTGTGTATCTCATGTTATATATCAATAA
AT
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protein sequence of SMED30025418-orf-1

>SMED30025418-orf-1 ID=SMED30025418-orf-1|Name=SMED30025418-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=388bp
MNQKHFTTDDLVKLNRIYKRQKQLKSDIKDLEEEFYDITTRMKTLGCIID
GRIEDSHTRNLRIGTKKFNHNPEEGIEYLVSKKAIQETPKAIATFLTDKS
LNKRAVGDYLGNISKPFNCDVLQEYISLFDFSEMEFIDSIRFFLSGFHLP
GESQKIDKIISLWAKYYHEQNPSIFKNENETYIMTYAVIMLNTCLHNPTA
KKENGGFGREEDFIKIMGNFNSDTQFELSFVKRIFKNIKSNPLLCLHKHL
PDNKYNSDISNIEKAGWLWKQGGRIKNMKKRWFVLSEYSLFYFIHPNSQS
LKGMIPLENLLIRMSCDKSSKPCFEIYSNENEIIKGCKSKKSGQIIKGHH
YSYKIYCFSQEEMESWMDAIQRSIDLITQMKLVKEIE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
Vocabulary: INTERPRO
TermDefinition
IPR035999Sec7_dom_sf
IPR000904Sec7_dom
IPR001849PH_domain
IPR023394Sec7_C_sf
IPR011993PH-like_dom_sf
Vocabulary: biological process
TermDefinition
GO:0032012regulation of ARF protein signal transduction
GO:0043547positive regulation of GTPase activity
Vocabulary: molecular function
TermDefinition
GO:0005086ARF guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 14..34
NoneNo IPR availableGENE3DG3DSA:1.10.220.20coord: 50..130
e-value: 1.8E-21
score: 77.7
NoneNo IPR availablePANTHERPTHR10663GUANYL-NUCLEOTIDE EXCHANGE FACTORcoord: 9..377
NoneNo IPR availablePANTHERPTHR10663:SF323CYTOHESIN-4coord: 9..377
NoneNo IPR availableSUPERFAMILYSSF50729PH domain-likecoord: 260..379
IPR000904Sec7 domainSMARTSM00222sec7_5coord: 54..243
e-value: 2.4E-45
score: 166.6
IPR000904Sec7 domainPFAMPF01369Sec7coord: 59..242
e-value: 3.5E-53
score: 180.0
IPR000904Sec7 domainPROSITEPS50190SEC7coord: 59..241
score: 30.591
IPR000904Sec7 domainCDDcd00171Sec7coord: 59..243
e-value: 1.03753E-46
score: 155.844
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 262..377
e-value: 1.5E-18
score: 77.7
IPR001849Pleckstrin homology domainPFAMPF00169PHcoord: 263..374
e-value: 2.4E-16
score: 60.1
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 261..375
score: 15.799
IPR023394Sec7, C-terminal domain superfamilyGENE3DG3DSA:1.10.1000.11coord: 131..249
e-value: 6.3E-30
score: 105.4
IPR011993PH-like domain superfamilyGENE3DG3DSA:2.30.29.30coord: 253..376
e-value: 2.7E-32
score: 113.6
IPR035999Sec7 domain superfamilySUPERFAMILYSSF48425Sec7 domaincoord: 57..243