Multidrug and toxin extrusion protein

Overview
NameMultidrug and toxin extrusion protein
Smed IDSMED30025415
Length (bp)423
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Multidrug and toxin extrusion protein (SMED30025415) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Multidrug and toxin extrusion protein (SMED30025415) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025415

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
Smed sexual biotypeSMED30025415h1SMcG0000265 Contig38832newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025415h1SMcG0000265 Contig38832uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30025415h1SMcG0000265 dd_Smed_v4_7241_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025415h1SMcG0000265 dd_Smed_v4_7241_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30025415h1SMcG0000265 dd_Smed_v4_7241_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
tail regionSMED30025415h1SMcG0000265 dd_Smed_v6_7241_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 49.2914 bits (116), Expect = 3.268e-7
Identity = 29/83 (34.94%), Postives = 47/83 (56.63%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILARR--TQNIE 321
            S F+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T +  G GL+     ++++   +QN++
Sbjct:   29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGVSVGFGLSSACDTLISQTYGSQNLK 110
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 49.2914 bits (116), Expect = 4.693e-7
Identity = 27/66 (40.91%), Postives = 38/66 (57.58%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            S F+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T +  G GL+
Sbjct:   29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGVSVGFGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Match: SLC47A1 (solute carrier family 47 member 1 [Source:HGNC Symbol;Acc:HGNC:25588])

HSP 1 Score: 49.2914 bits (116), Expect = 4.718e-7
Identity = 27/66 (40.91%), Postives = 38/66 (57.58%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            S F+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T +  G GL+
Sbjct:   29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGVSVGFGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723])

HSP 1 Score: 48.1358 bits (113), Expect = 4.045e-7
Identity = 36/100 (36.00%), Postives = 51/100 (51.00%), Query Frame = 1 
Query:   34 DAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILARRT---QNIEE 324
            DA   ++     + P GF  EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T I  G GL+    D L  +T   QN++ 
Sbjct:   15 DAASERRGLRCLLLP-GFLEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGISVGHGLSS-ACDTLISQTYGSQNLKH 111
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Match: Slc47a1 (solute carrier family 47, member 1 [Source:MGI Symbol;Acc:MGI:1914723])

HSP 1 Score: 47.7506 bits (112), Expect = 9.861e-7
Identity = 28/65 (43.08%), Postives = 37/65 (56.92%), Query Frame = 1 
Query:   82 GFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            GF  EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T I  G GL+
Sbjct:   30 GFLEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGISVGHGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q5I0E9|S47A1_RAT (Multidrug and toxin extrusion protein 1 OS=Rattus norvegicus OX=10116 GN=Slc47a1 PE=1 SV=1)

HSP 1 Score: 50.8322 bits (120), Expect = 5.561e-7
Identity = 29/66 (43.94%), Postives = 39/66 (59.09%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            SGF+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T I  G GL+
Sbjct:   28 SGFQEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGISVGHGLS 92
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q5RFD2|S47A1_PONAB (Multidrug and toxin extrusion protein 1 OS=Pongo abelii OX=9601 GN=SLC47A1 PE=2 SV=1)

HSP 1 Score: 49.6766 bits (117), Expect = 1.513e-6
Identity = 29/74 (39.19%), Postives = 43/74 (58.11%), Query Frame = 1 
Query:   55 TRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            +RF ++  S F+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T +  G GL+
Sbjct:   23 SRFLRL--SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGVSVGFGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q96FL8|S47A1_HUMAN (Multidrug and toxin extrusion protein 1 OS=Homo sapiens OX=9606 GN=SLC47A1 PE=1 SV=1)

HSP 1 Score: 49.2914 bits (116), Expect = 2.266e-6
Identity = 27/66 (40.91%), Postives = 38/66 (57.58%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            S F+ EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T +  G GL+
Sbjct:   29 SAFREELRALLVLAGPAFLVQLMVFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGVSVGFGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Match: sp|Q8K0H1|S47A1_MOUSE (Multidrug and toxin extrusion protein 1 OS=Mus musculus OX=10090 GN=Slc47a1 PE=1 SV=2)

HSP 1 Score: 47.7506 bits (112), Expect = 6.898e-6
Identity = 28/65 (43.08%), Postives = 37/65 (56.92%), Query Frame = 1 
Query:   82 GFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            GF  EL++LL +  P  L     FL   IS + CGHL  LE DA +LA +V  ++T I  G GL+
Sbjct:   30 GFLEELRALLVLAGPAFLAQLMMFLISFISSVFCGHLGKLELDAVTLAIAV-INVTGISVGHGLS 93
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0H3YKK1 (Multidrug and toxin extrusion protein OS=Schmidtea mediterranea OX=79327 GN=slc47a-1 PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 2.612e-11
Identity = 33/50 (66.00%), Postives = 39/50 (78.00%), Query Frame = 1 
Query:   85 FKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSV 234
            FK E+ SL+ IF P VLT+FFR LNP+ISL+MCGH S  EFD  SLANS+
Sbjct:   38 FKQEIFSLMSIFIPSVLTTFFRMLNPVISLIMCGHFSKYEFDVVSLANSI 87
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0H3YJI2 (Multidrug and toxin extrusion protein (Fragment) OS=Schmidtea mediterranea OX=79327 GN=slc47a-4 PE=2 SV=1)

HSP 1 Score: 67.3958 bits (163), Expect = 3.543e-10
Identity = 37/87 (42.53%), Postives = 54/87 (62.07%), Query Frame = 1 
Query:   85 FKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILARRTQNIEENMSKHKL 345
            F  ELK LL + +PI+L + FRFLNP IS++MCGHL+  EFDAASLAN++        FG+ ++  ++         I  + ++HKL
Sbjct:   23 FLPELKCLLKLAWPIILMNLFRFLNPTISVIMCGHLTKKEFDAASLANALINV-----FGVSVDLGFSTACDTLFARIYGSRNRHKL 104
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A183VN31 (Uncharacterized protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS1887 PE=4 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.775e-9
Identity = 28/62 (45.16%), Postives = 39/62 (62.90%), Query Frame = 1 
Query:   49 KQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSV 234
            ++ +    F +   +ELK L  I  P ++T   RF+NP IS+M+CGHLS  E DAASLAN +
Sbjct:    4 RKLQLGATFNNDRAAELKRLFVIAMPTMITQLLRFINPSISVMVCGHLSREELDAASLANCI 65
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: Q5BSB7 (SJCHGC05175 protein OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.779e-9
Identity = 27/49 (55.10%), Postives = 36/49 (73.47%), Query Frame = 1 
Query:   91 SELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVS 237
            +ELK LL +  P +L+   RF+NP IS+M+CGHLS  E DAASLAN ++
Sbjct:    8 NELKKLLMLALPTMLSQLLRFINPSISVMVCGHLSREELDAASLANCIT 56
[Close]
BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Match: A0A0X3PWQ5 (Multidrug and toxin extrusion protein OS=Schistocephalus solidus OX=70667 GN=TR150483 PE=3 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 6.863e-9
Identity = 29/52 (55.77%), Postives = 40/52 (76.92%), Query Frame = 1 
Query:   79 SGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSV 234
            +GF  ELK ++ + +P++LT   RF+NP +S+M+CGHLS  E DAASLANSV
Sbjct:    6 NGFIQELKCIVSLAWPLMLTHLLRFINPSLSIMICGHLSREELDAASLANSV 57
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Match: slc47a3 (multidrug and toxin extrusion protein 1-like [Source:NCBI gene;Acc:103046114])

HSP 1 Score: 44.669 bits (104), Expect = 8.065e-6
Identity = 21/68 (30.88%), Postives = 38/68 (55.88%), Query Frame = 1 
Query:   70 IFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGL 273
            +FP   K E+K L  +  P++L+    +L   +S + CGHL + E D  +LA ++  +++ +  G GL
Sbjct:   19 LFPEEVKKEVKELSALALPVLLSYIMVYLISFVSTVFCGHLGSTELDGVALAIAI-LNVSSVAVGYGL 85
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: slc47a3 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101163594])

HSP 1 Score: 49.6766 bits (117), Expect = 1.617e-7
Identity = 25/72 (34.72%), Postives = 40/72 (55.56%), Query Frame = 1 
Query:   58 RFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGL 273
            R + + P GFKSE+K +  +  P+++     F    +S + CGHL   E    SLA +VS ++T +  G+GL
Sbjct:   26 RIRMLVPVGFKSEIKEMSKLAGPVMIAQLMSFAVSFVSTVFCGHLGRTELAGVSLAIAVS-NVTGVSIGVGL 96
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Match: ENSORLT00000002449.2 (multidrug and toxin extrusion protein 1 [Source:NCBI gene;Acc:101156384])

HSP 1 Score: 46.595 bits (109), Expect = 2.156e-6
Identity = 22/73 (30.14%), Postives = 40/73 (54.79%), Query Frame = 1 
Query:   58 RFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLN 276
            R +   P  +++ELK L  +  P+V++    F+   +S++ CGHL   E    SL+ ++  ++T I  G GL+
Sbjct:   38 RMRGFIPEEYRNELKHLFRLAGPVVISQLMVFMISFVSMVFCGHLGKTELAGVSLSIAI-INVTGISIGTGLS 109
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000065608.1 (SMESG000065608.1)

HSP 1 Score: 162.54 bits (410), Expect = 1.344e-47
Identity = 77/77 (100.00%), Postives = 77/77 (100.00%), Query Frame = 1 
Query:    1 SSEEYAAKYKLDAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANS 231
            SSEEYAAKYKLDAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANS
Sbjct:   10 SSEEYAAKYKLDAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANS 86
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005477.1 (SMESG000005477.1)

HSP 1 Score: 68.1662 bits (165), Expect = 5.477e-14
Identity = 33/86 (38.37%), Postives = 49/86 (56.98%), Query Frame = 1 
Query:    7 EEYAAKYKLDAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFG 264
            ++   ++ +D  +    + +      +  ELK L  + +PIVL + FRFLNP IS++MCGHL   EFDAASLAN +    T +  G
Sbjct:  779 DQAVLRHDIDGIQVYGGKLRNWLSEKYFPELKELAKLAWPIVLMNLFRFLNPTISVIMCGHLRKTEFDAASLANLIQVFGTSVDLG 864

HSP 2 Score: 65.0846 bits (157), Expect = 5.899e-13
Identity = 33/57 (57.89%), Postives = 40/57 (70.18%), Query Frame = 1 
Query:   64 QKIFPSGFKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSV 234
            +K FP     ELK L  + +PIVL + FRFLNP IS++MCGHL   EFDAASLAN +
Sbjct:   38 EKYFP-----ELKELAKLAWPIVLMNLFRFLNPTISVIMCGHLRKTEFDAASLANVI 89
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005474.1 (SMESG000005474.1)

HSP 1 Score: 67.3958 bits (163), Expect = 8.754e-14
Identity = 38/87 (43.68%), Postives = 56/87 (64.37%), Query Frame = 1 
Query:   85 FKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILARRTQNIEENMSKHKL 345
            F  ELK LL + +PI+L + FRFLNP IS++MCGHL+  EFDAASLAN++  ++  +   +G +     + AR    I  + ++HKL
Sbjct:    5 FLPELKCLLKLAWPIILMNLFRFLNPTISVIMCGHLTKKEFDAASLANAL-INVFGVSVDLGFSTACDTLFAR----IYGSRNRHKL 86
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005474.1 (SMESG000005474.1)

HSP 1 Score: 67.3958 bits (163), Expect = 8.796e-14
Identity = 37/87 (42.53%), Postives = 54/87 (62.07%), Query Frame = 1 
Query:   85 FKSELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILARRTQNIEENMSKHKL 345
            F  ELK LL + +PI+L + FRFLNP IS++MCGHL+  EFDAASLAN++        FG+ ++  ++         I  + ++HKL
Sbjct:   23 FLPELKCLLKLAWPIILMNLFRFLNPTISVIMCGHLTKKEFDAASLANALINV-----FGVSVDLGFSTACDTLFARIYGSRNRHKL 104
[Close]
BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Match: SMESG000005476.1 (SMESG000005476.1)

HSP 1 Score: 66.6254 bits (161), Expect = 1.667e-13
Identity = 40/83 (48.19%), Postives = 48/83 (57.83%), Query Frame = 1 
Query:    4 SEEYAAKYKLDAPKPKQTRFQKIFPSGFKS--------ELKSLLWIFFPIVLTSFFRFLNPMISLMMCGHLSTLEFDAASLAN 228
             EE A +   D    +  R Q  F   FK+        ELK LL + +PIVL + FRFLNP IS++MCGHL   EFDAASLAN
Sbjct:   38 DEELATRMGKDDFVVQIARIQS-FGGKFKNWLSDKYYPELKELLKLAWPIVLMNLFRFLNPTISIIMCGHLRKAEFDAASLAN 119
The following BLAST results are available for this feature:
BLAST of Multidrug and toxin extrusion protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
SLC47A13.268e-734.94solute carrier family 47 member 1 [Source:HGNC Sym... [more]
SLC47A14.693e-740.91solute carrier family 47 member 1 [Source:HGNC Sym... [more]
SLC47A14.718e-740.91solute carrier family 47 member 1 [Source:HGNC Sym... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Slc47a14.045e-736.00solute carrier family 47, member 1 [Source:MGI Sym... [more]
Slc47a19.861e-743.08solute carrier family 47, member 1 [Source:MGI Sym... [more]
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BLAST of Multidrug and toxin extrusion protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q5I0E9|S47A1_RAT5.561e-743.94Multidrug and toxin extrusion protein 1 OS=Rattus ... [more]
sp|Q5RFD2|S47A1_PONAB1.513e-639.19Multidrug and toxin extrusion protein 1 OS=Pongo a... [more]
sp|Q96FL8|S47A1_HUMAN2.266e-640.91Multidrug and toxin extrusion protein 1 OS=Homo sa... [more]
sp|Q8K0H1|S47A1_MOUSE6.898e-643.08Multidrug and toxin extrusion protein 1 OS=Mus mus... [more]
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BLAST of Multidrug and toxin extrusion protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0H3YKK12.612e-1166.00Multidrug and toxin extrusion protein OS=Schmidtea... [more]
A0A0H3YJI23.543e-1042.53Multidrug and toxin extrusion protein (Fragment) O... [more]
A0A183VN311.775e-945.16Uncharacterized protein OS=Trichobilharzia regenti... [more]
Q5BSB71.779e-955.10SJCHGC05175 protein OS=Schistosoma japonicum OX=61... [more]
A0A0X3PWQ56.863e-955.77Multidrug and toxin extrusion protein OS=Schistoce... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
slc47a38.065e-630.88multidrug and toxin extrusion protein 1-like [Sour... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Multidrug and toxin extrusion protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
slc47a31.617e-734.72multidrug and toxin extrusion protein 1 [Source:NC... [more]
ENSORLT00000002449.22.156e-630.14multidrug and toxin extrusion protein 1 [Source:NC... [more]
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BLAST of Multidrug and toxin extrusion protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000065608.11.344e-47100.00SMESG000065608.1[more]
SMESG000005477.15.477e-1438.37SMESG000005477.1[more]
SMESG000005474.18.754e-1443.68SMESG000005474.1[more]
SMESG000005474.18.796e-1442.53SMESG000005474.1[more]
SMESG000005476.11.667e-1348.19SMESG000005476.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025415 ID=SMED30025415|Name=Multidrug and toxin extrusion protein|organism=Schmidtea mediterranea sexual|type=transcript|length=423bp
TCCAGTGAAGAATATGCCGCCAAATATAAATTAGACGCCCCTAAACCGAA
ACAAACACGTTTTCAGAAAATATTTCCTAGTGGATTTAAAAGTGAACTCA
AAAGCCTTTTATGGATATTTTTTCCAATTGTTCTCACCAGCTTTTTCAGA
TTTCTCAATCCTATGATAAGTTTGATGATGTGTGGTCATTTGAGCACTTT
AGAATTTGATGCTGCCTCTCTGGCAAACAGTGTAAGTTTTTCAATGACAC
AAATTCCATTCGGTATCGGTTTAAACCAGTGGTATGCAGACATTTTAGCT
CGCCGCACACAAAATATTGAAGAAAATATGTCAAAGCACAAACTAAGAGT
AATAAACTAAAATTCGAAAATAACTAAGAAAATTCGATAAAAAAATTGAA
TCTCTCTCTTATACAAAATTCCA
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protein sequence of SMED30025415-orf-1

>SMED30025415-orf-1 ID=SMED30025415-orf-1|Name=SMED30025415-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=120bp
SSEEYAAKYKLDAPKPKQTRFQKIFPSGFKSELKSLLWIFFPIVLTSFFR
FLNPMISLMMCGHLSTLEFDAASLANSVSFSMTQIPFGIGLNQWYADILA
RRTQNIEENMSKHKLRVIN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0042908xenobiotic transport
GO:0006855drug transmembrane transport
GO:0055085transmembrane transport
Vocabulary: molecular function
TermDefinition
GO:0042910xenobiotic transporter activity
GO:0015238drug transmembrane transporter activity
GO:0015297antiporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000421tail
PLANA:0003116parenchymal cell
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableTMHMMTMhelixcoord: 31..48