Anoctamin

Overview


Name	Anoctamin
Smed ID	SMED30025382
Length (bp)	2731

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Anoctamin (SMED30025382) t-SNE clustered cells

Violin plots show distribution of expression levels for Anoctamin (SMED30025382) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Anoctamin (SMED30025382) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Anoctamin (SMED30025382) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025382

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30025382	h1SMcG0014195	dd_Smed_v4_4761_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30025382	h1SMcG0014195	dd_Smed_v4_4761_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30025382	h1SMcG0014195	dd_Smed_v4_4761_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30025382	h1SMcG0014195	dd_Smed_v4_4761_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30025382	h1SMcG0014195	dd_Smed_v4_4761_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30025382	h1SMcG0014195	dd_4761	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
secretory system	SMED30025382	h1SMcG0014195	dd_Smed_v6_4761_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Anoctamin vs. Ensembl Human
Match: ANO7 (anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677])

HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0
Identity = 404/835 (48.38%), Postives = 573/835 (68.62%), Query Frame = 2

Query:  194 KANDYGTV---NEEGIEEEAAVPPLAYSGYYFNDGKSKI-DFILAWSEK---EKEPHSKA--------LYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRY-RFDSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            K   YG+    +E G ++ AA      +G   +  K +I DF+L W E    +++  S A         +R+ F  NL+ AGL +++   + G    HY  +   W ++C +AE L L+ PLQ  PN + +WS   L  L IPN++    P+ PP++Y+C F+ +K+ RFLGS+N+ T+F+ST+RHQ++ EIL    YG  +K  +GI +++ + +  +A+PLH+GP++ +  E  Q  +LN RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C   +SF MCPLC   + C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRK+A+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP+  R  R+L G V I++M+ VV++ ++++I+YR ++ I + +  N LL   A   A+ T ++VNLV I+ L+K+Y  +A  LT WEMHRTQ+ F++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCLIELA +L +IMVGKQ+I+N+QEVL+PKL+ W+ +F +   ++ +  + + +    +++D +L+P EGL DEYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP+ YYR+ R   L G+ N +L+ +P +        CRY  +RD+DG   Q +W LLA+RL FVIVFEH V  +G+LLDLL+PD+P+ + IK+KRE YLAKQAL + +++
Sbjct:   78 KRGSYGSTAHASEPGGQQAAAC----RAG---SPAKPRIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK-TPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKF-RLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVL 900

[Close]

BLAST of Anoctamin vs. Ensembl Human
Match: ANO7 (anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677])

HSP 1 Score: 712.99 bits (1839), Expect = 0.000e+0
Identity = 384/807 (47.58%), Postives = 544/807 (67.41%), Query Frame = 2

Query:  194 KANDYGTV---NEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSEK---EKEPHSKA--------LYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRY-RFDSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIP 2548
            K   YG+    +E G ++ AA      +G   +  K +IDF+L W E    +++  S A         +R+ F  NL+ AGL +++   + G    HY  +   W ++C +AE L L+ PLQ  PN + +WS   L  L IPN++    P+ PP++Y+C F+ +K+ RFLGS+N+ T+F+ST+RHQ++ EIL    YG  +K  +GI +++ + +  +A+PLH+GP++ +  E  Q  +LN RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C   +SF MCPLC   + C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRK+A+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP+  R  R+L G V I++M+ VV++ ++++I+YR ++ I + +  N LL   A   A+ T ++VNLV I+ L+K+Y  +A  LT WEMHRTQ+ F++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCLIELA +L +IMVGKQ+I+N+QEVL+PKL+ W+ +F +   ++ +  + + +    +++D +L+P EGL DEYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP+ YYR+ R   L G+ N +L+ +P +        CRY  +RD+DG   Q +W LLA+RL FVIVFE   A  G  +  + P
Sbjct:   78 KRGSYGSTAHASEPGGQQAAAC----RAG---SPAKPRIDFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK-TPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKF-RLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEVAEAPAGSPIHGMRP 872

[Close]

BLAST of Anoctamin vs. Ensembl Human
Match: ANO1 (anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625])

HSP 1 Score: 545.814 bits (1405), Expect = 0.000e+0
Identity = 333/816 (40.81%), Postives = 486/816 (59.56%), Query Frame = 2

Query:  347 KALYRKKFESNLKKAGLELEEDFDETGKFH---YIKIYVPWEIMCRFAEKLALRAPLQA--HPNPSDDWSMKALNCLH--IPNIMYLDAPNKPPDF--YTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALC---SIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMM--TXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFF-GLRNEDCQNGGCLIELAMQLAIIMVGKQII-SNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLS----------WSPKNS-----TVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQAL----QDAD--LITWETFENEKE 2659
            K   R+++E NL +AGLELE D  E  K H   ++KI+ PW ++CR AE L L+ P +   H N +     K  + L      I    A ++P      +  F + K H F   ++K ++F S  R  +V EIL+ +    + K  +GI  ++ + +Y +AYPLH+G Y     E       N R++LYE WARYG +Y+YQP+D +R+YFGEKIG YFAW+G+YT  L+PASI+GI VFLYG  T D NI + E+C   ++  MCPLCD+   C YW++   C   + ++LFD+P T+F+S+FMA+WA TF+E+WKRK   L + WD+  +EEEE+ PRA+Y A     S+ +++      +       R P  LT +V I+ M+  T  I+  + +    +   + M  +P +R+N       TA I+NLV+I+ L +VY  IA  LT+ E+ +T+  F+ +LIFK FL +FVN Y+ IFY+AFFKGRFVG PG+Y Y F   R E+C  GGCL+EL +QL+IIM+GKQ+I +N+ E+ +PK++               H+ C       Y+ D  L P+ GL  EY+E+++QFGF+T+FVA+FPLAP FALLNN +EIRLDA+K V E +RPVA RAKDIG+W+ IL  I  +A I NAF+++FTS+F+P+L Y Y +    ++ G+ NH+LS           +P +       V  CRY  YR     +N   + + FW +LA RL FVIVF++ V  +   +D +IPD+PK++  +I +E  L  +      QD    L TW   E +K+
Sbjct:    8 KRFRREEYEGNLLEAGLELERD--EDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLF-DLSDKDSFFDSKTRSTIVYEILK-RTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEF------NDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKT--CSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQ-RYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKD 810

[Close]

BLAST of Anoctamin vs. Ensembl Human
Match: ANO3 (anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004])

HSP 1 Score: 540.036 bits (1390), Expect = 6.582e-179
Identity = 347/834 (41.61%), Postives = 496/834 (59.47%), Query Frame = 2

Query:  257 LAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE-EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWS---------MKALNCLHIPNIMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSK-TELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQ-KNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVT----FANGTAAI-VNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLSWSPKNSTVIP----CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +A SG  F DGK +ID+IL + +   +       R  FE NL+  GL LE E    +    +IKI++PW+ +C++AE+L +R P +     +D  S          + +      N M LD    P     D YT  F +++IH F+  NNK T+FS+  R ++V  +LE   Y          K ++++  Y +A+P HEG Y+ S+  +   P+  N+R +LYE WAR+G WY++QPLD IR YFGEKIG YFAW+G YT  L+PA+I+G+ VF YG+FT + +  ++EIC     F MCPLCD+   C    L D C++ K+ YLFD+ GT+F++IFMA+WA  FLE+WKR+ + L + WD++++EEEEE  R Q+ A     +  NP+TG  EP+ P   ++ R+L  +  I  M+++VI  +  V++YR+++   M Q    + N +     FA   AA+ +N ++IM L   YE IA  LT  E  RT+S+++N    K+FLFQFVN  SSIFYIAFF GRFVG+PG Y+  F   R E+C   GCLI+L +Q+ +IM  KQI +N  E+  P +Q W+ R     G    HD    + +  ++ D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  ILE I  +A I+NAF++A TS+++P+  Y Y++           + L GY N+SLS+   +   +     CRY  YR      K Y     +W +LA RL F+IVFEH V GI   +  LIPDVPK L+ +I+RE YL ++ + +A+L
Sbjct:    4 IASSGPLFKDGKKRIDYILVYRKTNIQYDK----RNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFI-INNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRK-LINNGSYIAAFPPHEGAYKSSQPIKTHGPQ--NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDK--NCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVV---MEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRG---IHD----ASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAEL 816

[Close]

BLAST of Anoctamin vs. Ensembl Human
Match: ANO3 (anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004])

HSP 1 Score: 541.962 bits (1395), Expect = 5.184e-178
Identity = 347/834 (41.61%), Postives = 498/834 (59.71%), Query Frame = 2

Query:  257 LAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE-EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWS---------MKALNCLHIPNIMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSK-TELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQ-KNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVT----FANGTAAI-VNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLSWSPKNSTVIP----CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +A SG  F DGK +ID+IL +    ++ + +   R  FE NL+  GL LE E    +    +IKI++PW+ +C++AE+L +R P +     +D  S          + +      N M LD    P     D YT  F +++IH F+  NNK T+FS+  R ++V  +LE   Y          K ++++  Y +A+P HEG Y+ S+  +   P+  N+R +LYE WAR+G WY++QPLD IR YFGEKIG YFAW+G YT  L+PA+I+G+ VF YG+FT + +  ++EIC     F MCPLCD+   C    L D C++ K+ YLFD+ GT+F++IFMA+WA  FLE+WKR+ + L + WD++++EEEEE  R Q+ A     +  NP+TG  EP+ P   ++ R+L  +  I  M+++VI  +  V++YR+++   M Q    + N +     FA   AA+ +N ++IM L   YE IA  LT  E  RT+S+++N    K+FLFQFVN  SSIFYIAFF GRFVG+PG Y+  F   R E+C   GCLI+L +Q+ +IM  KQI +N  E+  P +Q W+ R     G    HD    + +  ++ D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  ILE I  +A I+NAF++A TS+++P+  Y Y++           + L GY N+SLS+   +   +     CRY  YR      K Y     +W +LA RL F+IVFEH V GI   +  LIPDVPK L+ +I+RE YL ++ + +A+L
Sbjct:  134 IASSGPLFKDGKKRIDYILVY----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFI-INNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRK-LINNGSYIAAFPPHEGAYKSSQPIKTHGPQ--NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDK--NCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVV---MEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRG---IHD----ASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAEL 946

[Close]

BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 212.616 bits (540), Expect = 2.165e-57
Identity = 214/828 (25.85%), Postives = 371/828 (44.81%), Query Frame = 2

Query:  299 IDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPL---QAHPN-PSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILE-------------------------TQLYXXXXXXXXXXXXMVDDEIYDSAYPLH----EGPY--------ECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYL-----FDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEE-EEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNED-CQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWF----YRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            IDF+L       E  SK  YR+ FE  ++K GL +     ++G+ H+  I  P+  + R AE   +  PL   Q  P  PS         C+ +  I   D   +   F    F++     FL  +++ ++F+S+QR  +  +IL                          + +    +    G+  ++  ++Y+ A+ LH    E PY          +  E     +L+ R+ L   W R   WY++QPL+ IR+YFGE+I +YFAW G +   L PA I G+ VF+YG   F  +IS+  +   +          E + C       V +F  +        FD     F+++FM++W   F++ WKR N+ L++ W+  D+   E +RP  + + +    +++P+TG      P   R  ++L   V +   M VV+I ++ V + ++ +            +    A    +I+N +  M L  +Y  +  +L  WE HRT+S+ +N LI K+F FQ VN Y+S+FY+AF +    G   N  +  G   +D C +  C   LA+QL    + K      ++V++P     F    Y        +++ D  +N   ++ +E  K    + +L E  E ++ FG   +F + FPLAP  AL+  ++++R+DA +L+   ++P+      IG+W  IL  +   A  +NAF++AFTS F                           ST +          DG      +  +  RL  VIVF++ V G+  LL  +IP +P  + + ++++ Y+    ++  D+
Sbjct:   19 IDFVLV--HNAAESRSKGKYREFFEKAVQKEGLIIRHQ--QSGQTHFTLISTPFHRLTREAEMSQMCFPLKDCQVKPGLPS--------CCIPLSQIFVTDDTVR---FINAPFQRKHGSLFLNYHDEKSFFTSSQRGYLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSITSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLNWER---WYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYG---FIDSISSAPLDWNHCKVVNFIGQTENVACGM--RNGVTLFFSMVTQWFMSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDFHAIEPDRPEFRGSKV----KEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNTLSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGLQPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQAN---VLVREWLKPSAGDFVLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGFC--------------------------STFLA---------DGA-----YCTVQNRLIIVIVFQNLVFGLKYLLSSVIPSIPASIKLALRKKRYVVAHIVEKGDV 776

[Close]

BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-1 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286])

HSP 1 Score: 212.231 bits (539), Expect = 3.236e-57
Identity = 214/828 (25.85%), Postives = 371/828 (44.81%), Query Frame = 2

Query:  299 IDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPL---QAHPN-PSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILE-------------------------TQLYXXXXXXXXXXXXMVDDEIYDSAYPLH----EGPY--------ECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYL-----FDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEE-EEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNED-CQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWF----YRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            IDF+L       E  SK  YR+ FE  ++K GL +     ++G+ H+  I  P+  + R AE   +  PL   Q  P  PS         C+ +  I   D   +   F    F++     FL  +++ ++F+S+QR  +  +IL                          + +    +    G+  ++  ++Y+ A+ LH    E PY          +  E     +L+ R+ L   W R   WY++QPL+ IR+YFGE+I +YFAW G +   L PA I G+ VF+YG   F  +IS+  +   +          E + C       V +F  +        FD     F+++FM++W   F++ WKR N+ L++ W+  D+   E +RP  + + +    +++P+TG      P   R  ++L   V +   M VV+I ++ V + ++ +            +    A    +I+N +  M L  +Y  +  +L  WE HRT+S+ +N LI K+F FQ VN Y+S+FY+AF +    G   N  +  G   +D C +  C   LA+QL    + K      ++V++P     F    Y        +++ D  +N   ++ +E  K    + +L E  E ++ FG   +F + FPLAP  AL+  ++++R+DA +L+   ++P+      IG+W  IL  +   A  +NAF++AFTS F                           ST +          DG      +  +  RL  VIVF++ V G+  LL  +IP +P  + + ++++ Y+    ++  D+
Sbjct:   37 IDFVLV--HNAAESRSKGKYREFFEKAVQKEGLIIRHQ--QSGQTHFTLISTPFHRLTREAEMSQMCFPLKDCQVKPGLPS--------CCIPLSQIFVTDDTVR---FINAPFQRKHGSLFLNYHDEKSFFTSSQRGYLTYQILTKIDISKDLKGERLGESQDEPTDPSTSSITSDEQLRRKGLSWLLMSDVYEEAFVLHAPSKEEPYFKAMQNGSVKAYNEFISEIELDPRRSLSLNWER---WYKFQPLNKIRDYFGEQIAYYFAWQGTFLTLLWPAVIFGLVVFIYG---FIDSISSAPLDWNHCKVVNFIGQTENVACGM--RNGVTLFFSMVTQWFMSSFDTKMNAFFAVFMSIWGSVFVQIWKRNNSVLSYQWNSDDFHAIEPDRPEFRGSKV----KEDPITGEDIWISPALARYIKMLASFVFVSFSMLVVVISLMLVTLLKIWMVYNFQCTKEYTFHCWLSAAFLPSILNTLSAMGLGAIYSNLVSRLNSWENHRTESEHNNSLIVKIFAFQMVNTYTSLFYVAFIRPESHGLQPNGLFGLGTEFKDTCLDDTCSSLLALQLLTHTLIKPFPKFFKDVVLPYFVKLFRLRMYTSRTEARVEIEDDDQAN---VLVREWLKPSAGDFVLWEMNEKIILFGTTMMFASLFPLAPLLALIIGFVDMRIDAHRLIWFNRKPIPIITNGIGIWLPILTFLQYCAVFTNAFIVAFTSGFC--------------------------STFLA---------DGA-----YCTVQNRLIIVIVFQNLVFGLKYLLSSVIPSIPASIKLALRKKRYVVAHIVEKGDV 794

[Close]

BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 108.227 bits (269), Expect = 9.746e-24
Identity = 87/363 (23.97%), Postives = 157/363 (43.25%), Query Frame = 2

Query:  923 QPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEE--ERPRAQYAALCSIFQKNPVTGVIEPYFP--KERRLPRILT---GIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVP------KLQTWFYRFSKGLGE 1972
            QP+D +++YFG +I  YFAW+G  T  L   S++GI ++  G F +  +   K+                     Y  + D+C              + ++ F  +W+  +LE+WKR  A LA  W   D  ++   + PR  +         NPV+G +EP++P  K   +  ++T     +C++ M   ++       +           + L     + +A         ++I+   K+Y  +AL L + E +RT  ++++ LI K+ LFQFV  + S+FYIAF                 LR+        +  L   LA +++ +Q+  NI E +VP      KL +  Y+ ++ + +
Sbjct:  213 QPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGDKQDL-------------------YQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQG--DYLAPNPVSGRLEPFYPAWKHTVMRYVITYPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYA---------LMIVISDKIYRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFV----------------LRD--------MKRLQETLATLLITRQVTQNIMETVVPFMIEKLKLSSLTYKMTRSMSD 508

HSP 2 Score: 69.3218 bits (168), Expect = 1.105e-11
Identity = 56/207 (27.05%), Postives = 95/207 (45.89%), Query Frame = 2

Query: 1994 SNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQ 2614
            SN  L   + ++ +  Y   LD++LE+ +QFG++ +F  AFPLA   AL+NN +EIR+DA KL    QRP   R KDIG W   +E +  +  I N  L+   S  + +++               LSW  +                              +  ++V EH +     ++D+L+PDVP  + I+  ++ +  ++A +
Sbjct:  603 SNPELTQAELESVMSVYARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIG-QSGLVQRIW-------------PDLSWGGQ------------------------------ILIIVVLEHVILASKMIIDILVPDVPHWVRIETAKQEHFRREAFK 765

[Close]

BLAST of Anoctamin vs. Ensembl Celegans
Match: anoh-2 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3])

HSP 1 Score: 108.227 bits (269), Expect = 1.022e-23
Identity = 87/363 (23.97%), Postives = 157/363 (43.25%), Query Frame = 2

Query:  923 QPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEE--ERPRAQYAALCSIFQKNPVTGVIEPYFP--KERRLPRILT---GIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVP------KLQTWFYRFSKGLGE 1972
            QP+D +++YFG +I  YFAW+G  T  L   S++GI ++  G F +  +   K+                     Y  + D+C              + ++ F  +W+  +LE+WKR  A LA  W   D  ++   + PR  +         NPV+G +EP++P  K   +  ++T     +C++ M   ++       +           + L     + +A         ++I+   K+Y  +AL L + E +RT  ++++ LI K+ LFQFV  + S+FYIAF                 LR+        +  L   LA +++ +Q+  NI E +VP      KL +  Y+ ++ + +
Sbjct:  269 QPIDQVKDYFGTEIAMYFAWLGHMTTALWFPSLLGILMWFLGGFKYKNSPGDKQDL-------------------YQLISDICF-------------VLFAFFNCIWSTIYLEWWKRVQAELAFKWGTYDATQDSYLQDPRPAFQG--DYLAPNPVSGRLEPFYPAWKHTVMRYVITYPITFLCVVGMFAAMLAIFTVQDLADFYFGDSWMLSWLCYFPMIFYA---------LMIVISDKIYRRLALILNDLENYRTDDEYEDFLITKIVLFQFVTAFGSLFYIAFV----------------LRD--------MKRLQETLATLLITRQVTQNIMETVVPFMIEKLKLSSLTYKMTRSMSD 564

HSP 2 Score: 69.3218 bits (168), Expect = 1.111e-11
Identity = 56/207 (27.05%), Postives = 95/207 (45.89%), Query Frame = 2

Query: 1994 SNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQ 2614
            SN  L   + ++ +  Y   LD++LE+ +QFG++ +F  AFPLA   AL+NN +EIR+DA KL    QRP   R KDIG W   +E +  +  I N  L+   S  + +++               LSW  +                              +  ++V EH +     ++D+L+PDVP  + I+  ++ +  ++A +
Sbjct:  659 SNPELTQAELESVMSVYARPLDDFLEMFIQFGYVLLFSPAFPLAAVCALINNLIEIRVDAFKLCNTVQRPFGRRVKDIGAWQKAMEILGILGVIVNCALIG-QSGLVQRIW-------------PDLSWGGQ------------------------------ILIIVVLEHVILASKMIIDILVPDVPHWVRIETAKQEHFRREAFK 821

[Close]

BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083806)

HSP 1 Score: 515.768 bits (1327), Expect = 1.039e-168
Identity = 323/831 (38.87%), Postives = 479/831 (57.64%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHS--KALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHP--------NPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX--XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC-AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPKER-RLPRILTG--IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQH----DSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSL------------SWSPKNSTVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDAD 2623
            +  +F D    IDF+LA+     EP        R+ FE+NL   GLE+E    +  +  ++KI+ P E++ R+AE L LR P++  P          S   S+K +    + NI Y+D    P   +      S+   +L    +  +F++  R ++V  IL+ Q +  + + ++   I+R++ + +Y +AYPLH+G         E  E    R +LY++WA   +WY+YQPLD I+EYFG KIG YFAW+G YT  LL ASI+G+  FLY  F+    +  K+IC +GN +  MCPLCD    C +W+LK+ C + K+ YL D+P T+F+++FM+ WA  FLE WKR +A + H WD+  ++  EE PR QY A        + + VT + EP  P  R +LP  +    +V +L+ +  V +  + V    +L  + +  +P+  ++A+  A  +AA VNL L+  L  +Y  +A  LTE EM RTQ+ FD+ L  K++L QFVN+Y+SIFYIAFFKG+FVG+PG Y+  F  R E+C +GGCL EL +QLAIIMVGKQ  + I EV +P           GL     +    D   +     +  D KL+ +   GL  EYLE+VLQ+GF+TIFVAAFPLAPFFALLNN +E+RLDA+KL+   +RPV++R +DIGVW+ IL+ I  ++ I+N F++AFTS+ +P+L YR+  +   +LDGY N +L            S +   S +  CRY  +R          L   F+ +LA RLGFV+VFE+ VA +  L+   IPD+  EL  +I+RE Y+  + + D +
Sbjct:   34 TSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESS--QKDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNI-YVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDG---------EITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD---WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDER---WMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQE 846

[Close]

BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334921)

HSP 1 Score: 515.768 bits (1327), Expect = 1.039e-168
Identity = 323/831 (38.87%), Postives = 479/831 (57.64%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHS--KALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHP--------NPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX--XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC-AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPKER-RLPRILTG--IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQH----DSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSL------------SWSPKNSTVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDAD 2623
            +  +F D    IDF+LA+     EP        R+ FE+NL   GLE+E    +  +  ++KI+ P E++ R+AE L LR P++  P          S   S+K +    + NI Y+D    P   +      S+   +L    +  +F++  R ++V  IL+ Q +  + + ++   I+R++ + +Y +AYPLH+G         E  E    R +LY++WA   +WY+YQPLD I+EYFG KIG YFAW+G YT  LL ASI+G+  FLY  F+    +  K+IC +GN +  MCPLCD    C +W+LK+ C + K+ YL D+P T+F+++FM+ WA  FLE WKR +A + H WD+  ++  EE PR QY A        + + VT + EP  P  R +LP  +    +V +L+ +  V +  + V    +L  + +  +P+  ++A+  A  +AA VNL L+  L  +Y  +A  LTE EM RTQ+ FD+ L  K++L QFVN+Y+SIFYIAFFKG+FVG+PG Y+  F  R E+C +GGCL EL +QLAIIMVGKQ  + I EV +P           GL     +    D   +     +  D KL+ +   GL  EYLE+VLQ+GF+TIFVAAFPLAPFFALLNN +E+RLDA+KL+   +RPV++R +DIGVW+ IL+ I  ++ I+N F++AFTS+ +P+L YR+  +   +LDGY N +L            S +   S +  CRY  +R          L   F+ +LA RLGFV+VFE+ VA +  L+   IPD+  EL  +I+RE Y+  + + D +
Sbjct:   34 TSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESS--QKDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNI-YVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDG---------EITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD---WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDER---WMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQE 846

[Close]

BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0083805)

HSP 1 Score: 513.457 bits (1321), Expect = 3.490e-166
Identity = 324/828 (39.13%), Postives = 479/828 (57.85%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHS--KALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHP--------NPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX--XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC-AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPKER-RLPRILTG--IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLI-IYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSW-----SPK-------NSTVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDAD 2623
            +  +F D    IDF+LA+     EP        R+ FE+NL   GLE+E    +  +  ++KI+ P E++ R+AE L LR P++  P          S   S+K +    + NI Y+D    P   +      S+   +L    +  +F++  R ++V  IL+ Q +  + + ++   I+R++ + +Y +AYPLH+G         E  E    R +LY++WA   +WY+YQPLD I+EYFG KIG YFAW+G YT  LL ASI+G+  FLY  F+    +  K+IC +GN +  MCPLCD    C +W+LK+ C + K+ YL D+P T+F+++FM+ WA  FLE WKR +A + H WD+  ++  EE PR QY A        + + VT + EP  P  R +LP  +    +V +L+ +  V +  + V    +L  + +  +P+  ++A+  A  +AA VNL L+  L  +Y  +A  LTE EM RTQ+ FD+ L  K++L QFVN+Y+SIFYIAFFKG+FVG+PG Y+  F  R E+C +GGCL EL +QLAIIMVGKQ  + I EV +P           GL     +    +      +  D KL+ +   GL  EYLE+VLQ+GF+TIFVAAFPLAPFFALLNN +E+RLDA+KL+   +RPV++R +DIGVW+ IL+ I  ++ I+N F++AFTS+ +P+L YR+  +   +LDGY N +LS      SP         S +  CRY  +R          L   F+ +LA RLGFV+VFE+ VA +  L+   IPD+  EL  +I+RE Y+  + + D +
Sbjct:  183 TSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESS--QKDQIWFVKIHAPLEVLRRYAEILKLRMPMKEIPGMSVVNRSTKSVFSSLKHVFQFFLRNI-YVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDG---------EITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD---WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQE 995

[Close]

BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0334922)

HSP 1 Score: 505.368 bits (1300), Expect = 2.083e-164
Identity = 324/855 (37.89%), Postives = 480/855 (56.14%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHS--KALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQ------------------AH--------------PNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX--XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC-AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPKER-RLPRILTG--IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQH----DSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSL------------SWSPKNSTVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDAD 2623
            +  +F D    IDF+LA+     EP        R+ FE+NL   GLE+E    +  +  ++KI+ P E++ R+AE L LR P++                  AH                 S   S+K +    + NI Y+D    P   +      S+   +L    +  +F++  R ++V  IL+ Q +  + + ++   I+R++ + +Y +AYPLH+G         E  E    R +LY++WA   +WY+YQPLD I+EYFG KIG YFAW+G YT  LL ASI+G+  FLY  F+    +  K+IC +GN +  MCPLCD    C +W+LK+ C + K+ YL D+P T+F+++FM+ WA  FLE WKR +A + H WD+  ++  EE PR QY A        + + VT + EP  P  R +LP  +    +V +L+ +  V +  + V    +L  + +  +P+  ++A+  A  +AA VNL L+  L  +Y  +A  LTE EM RTQ+ FD+ L  K++L QFVN+Y+SIFYIAFFKG+FVG+PG Y+  F  R E+C +GGCL EL +QLAIIMVGKQ  + I EV +P           GL     +    D   +     +  D KL+ +   GL  EYLE+VLQ+GF+TIFVAAFPLAPFFALLNN +E+RLDA+KL+   +RPV++R +DIGVW+ IL+ I  ++ I+N F++AFTS+ +P+L YR+  +   +LDGY N +L            S +   S +  CRY  +R          L   F+ +LA RLGFV+VFE+ VA +  L+   IPD+  EL  +I+RE Y+  + + D +
Sbjct:   34 TSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESS--QKDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNI-YVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDG---------EITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD---WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDER---WMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQE 870

[Close]

BLAST of Anoctamin vs. Ensembl Fly
Match: subdued (gene:FBgn0038721 transcript:FBtr0302492)

HSP 1 Score: 504.212 bits (1297), Expect = 2.557e-162
Identity = 325/851 (38.19%), Postives = 480/851 (56.40%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHS--KALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH--PNPSDDWSMKALNCLH-----IPNIMYLDAPNKP--------------PDFYTCEFKQSKIHRFLG--SNNKL--------TYFSSTQRHQVVNEILETQLYXXXXXXXXX--XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC-AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPKER-RLPRILTG--IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLI-IYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSW-----SPK-------NSTVIPCRYPGYR-----DNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDAD 2623
            +  +F D    IDF+LA+     EP        R+ FE+NL   GLE+E    +  +  ++KI+ P E++ R+AE L LR P++         + S +  N  H     IP +  ++   K                 +   E    + HRF    S +K          +F++  R ++V  IL+ Q +  + + ++   I+R++ + +Y +AYPLH+G         E  E    R +LY++WA   +WY+YQPLD I+EYFG KIG YFAW+G YT  LL ASI+G+  FLY  F+    +  K+IC +GN +  MCPLCD    C +W+LK+ C + K+ YL D+P T+F+++FM+ WA  FLE WKR +A + H WD+  ++  EE PR QY A        + + VT + EP  P  R +LP  +    +V +L+ +  V +  + V    +L  + +  +P+  ++A+  A  +AA VNL L+  L  +Y  +A  LTE EM RTQ+ FD+ L  K++L QFVN+Y+SIFYIAFFKG+FVG+PG Y+  F  R E+C +GGCL EL +QLAIIMVGKQ  + I EV +P           GL     +    +      +  D KL+ +   GL  EYLE+VLQ+GF+TIFVAAFPLAPFFALLNN +E+RLDA+KL+   +RPV++R +DIGVW+ IL+ I  ++ I+N F++AFTS+ +P+L YR+  +   +LDGY N +LS      SP         S +  CRY  +R          L   F+ +LA RLGFV+VFE+ VA +  L+   IPD+  EL  +I+RE Y+  + + D +
Sbjct:  183 TSLFFEDCVRSIDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESS--QKDQIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISERSNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIRQDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDG---------EITETGTMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD---WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEEHPRPQYLARLEHIPPTRVDYVTNIKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFDYRQEECSSGGCLTELCIQLAIIMVGKQAFNTILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSNITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQE 1019

[Close]

BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 839.721 bits (2168), Expect = 0.000e+0
Identity = 431/829 (51.99%), Postives = 596/829 (71.89%), Query Frame = 2

Query:  236 EEAAVPPLAYSGYYFNDGKSKIDFILAW----------------SEKEKEPHSK-----------ALYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSP---KNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            E+ A  P+ ++G YF DG++KIDF+L W                SE   EP  +           A +R KF  NL+ AGL +E++   + K   HY+K++ PW+++  +AE+L LRAPLQA P+P  + S + L  L +PNIM    PN+P D+YTC F++SK+ +FLGS+++  YF+STQRH++V EIL    YGRR++ E+G+ R++ D  +  A+PLHEGP++    +  QP++LN RQ+LY YWA + +W +YQPLDHIREYFGEKI  YFAW+G YTAWLLPA+++G  VF+ G+ T   N  AKEIC     + MCPLC+    C+ W + D+C   K+ YLFDHPGT+F+S+FM++WAVTFLEYWKRKNA+LAHHWD +D+ E+EE PR ++AA+    ++NPVTGV EPYFP++ R+ R+LTG + I++M+ VV+IF++ VIIYR ++ + MF+  + +LR  A   AN ++ +VNL LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y   FG+RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE ++PK++ W  + +    ++ Q           +++D +LIP EGL DEYLEIVLQFGFITIFVAAFPLAP FALLNNW+E+RLDA K VCE +RPVAERA+ IGVWF+ILE+++ ++ + NAFL+AFTS+FLP+L Y+Y+F++ L GY N +L++SP    +S+   CRY  +RD +G  K  +WELLAVRLGF+I FEH V  + +++D ++PD+P+ L +KIKRE YLAKQAL D
Sbjct:   61 EQTASAPVHHTGNYFRDGQTKIDFVLVWEVKVRRKRRSRGQAEASEGAAEPAQEESRSERRKAQLARWRDKFILNLQTAGLLMEKEESSSVKKTIHYLKLHAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWVPNIMKDSVPNRPVDYYTCAFRKSKMEKFLGSDDRENYFTSTQRHRIVYEILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCD-TQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLCET---CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPER----WEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 881

[Close]

BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 838.951 bits (2166), Expect = 0.000e+0
Identity = 431/829 (51.99%), Postives = 596/829 (71.89%), Query Frame = 2

Query:  236 EEAAVPPLAYSGYYFNDGKSKIDFILAW----------------SEKEKEPHSK-----------ALYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSP---KNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            E+ A  P+ ++G YF DG++KIDF+L W                SE   EP  +           A +R KF  NL+ AGL +E++   + K   HY+K++ PW+++  +AE+L LRAPLQA P+P  + S + L  L +PNIM    PN+P D+YTC F++SK+ +FLGS+++  YF+STQRH++V EIL    YGRR++ E+G+ R++ D  +  A+PLHEGP++    +  QP++LN RQ+LY YWA + +W +YQPLDHIREYFGEKI  YFAW+G YTAWLLPA+++G  VF+ G+ T   N  AKEIC     + MCPLC+    C+ W + D+C   K+ YLFDHPGT+F+S+FM++WAVTFLEYWKRKNA+LAHHWD +D+ E+EE PR ++AA+    ++NPVTGV EPYFP++ R+ R+LTG + I++M+ VV+IF++ VIIYR ++ + MF+  + +LR  A   AN ++ +VNL LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y   FG+RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE ++PK++ W  + +    ++ Q           +++D +LIP EGL DEYLEIVLQFGFITIFVAAFPLAP FALLNNW+E+RLDA K VCE +RPVAERA+ IGVWF+ILE+++ ++ + NAFL+AFTS+FLP+L Y+Y+F++ L GY N +L++SP    +S+   CRY  +RD +G  K  +WELLAVRLGF+I FEH V  + +++D ++PD+P+ L +KIKRE YLAKQAL D
Sbjct:   61 EQTASAPVHHTGNYFRDGQTKIDFVLVWEVKVRRKRRSRGQAEASEGAAEPAQEESRSERRKAQLARWRDKFILNLQTAGLLMEKEESSSVKKTIHYLKLHAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWVPNIMKDSVPNRPVDYYTCAFRKSKMEKFLGSDDRENYFTSTQRHRIVYEILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCD-TQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLCET---CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPER----WEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 881

[Close]

BLAST of Anoctamin vs. Ensembl Zebrafish
Match: si:dkey-83h2.5 (si:dkey-83h2.5 [Source:ZFIN;Acc:ZDB-GENE-131125-81])

HSP 1 Score: 765.377 bits (1975), Expect = 0.000e+0
Identity = 412/814 (50.61%), Postives = 576/814 (70.76%), Query Frame = 2

Query:  278 FNDGKSKIDFILAWSEK----------------EKEPHSKALYRKKFESNLKKAGL--ELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMF--QNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFY--RFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTV--IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFE 2647
            F+DG + IDF+L W E                  ++ H K  +R +F S L++AGL  E++E      K  Y+ +  PW ++C +AE+++LR PLQ    P  +WS   L  LHIPNIM  D PN PPD+YTC F+ +K+ RFLG  NK T+F +TQRHQ++ EIL    YG  ++GE+GI R+V +++  +A+PLHEGP++  KT+ E P+ LN RQIL+ YWAR+  W +YQPLDHIREYFGEKI  YFAW+G YT WLLPA+++G  +FL+G++    ++ A+E+C+  N+F MCPLC+    C +W L  +C   K   LFD+ GT+F+SIFM++WAVTFLEYWKR ++ L+H WD  ++EE EERPR ++ AL  +  +NPVTG  EPYFP+ RRL R LTG + I+LM+++V+IF++A+I+YR ++ I ++  Q+     +A   A+ T +++NL++I+ L+++Y  +A  LT WEMHRTQ++++N  I KVF+FQFVNFYSS  YIAFFKGRFVGYPG+Y+   G+RNEDC   GCLIELA +L +IMVGKQ+ISNIQE ++PKL+TW++  +      ++V  +  +NS +  ++ D +L+  EGL DEYLE+VLQFGFITIFVAA PLAP FAL+NNW+E+RLDAQK VCE +RPV ERA+DIG+W  IL+ I+ +A ISNAFL+AFTS+FLP+L+YRY   S+ GY N +LS +P N T   + CRY G RD  G   Q ++ LLA+RL FVI+FEH V  IG+++D ++PD+P+E+ IKIKRE Y+AK+AL +   ++    E
Sbjct:   42 FSDGVTTIDFVLVWEESGSPLKSADGDELSFSSSRDTHRK--WRTEFLSKLQEAGLHQEMKEVVQGKTKTTYVLLSAPWNVLCYYAEEISLRVPLQVVTTPISNWSETILEKLHIPNIMAQDVPNYPPDYYTCPFRTTKLERFLGHENKDTFFKTTQRHQILYEILARTPYGALKRGEVGIGRLVSEKVLTAAFPLHEGPFQLPKTQ-EDPQCLNMRQILHHYWARWACWRKYQPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLMVTDVPAEELCSSGNAFIMCPLCNI---CSHWNLSSICYTYKAGLLFDNGGTVFFSIFMSLWAVTFLEYWKRTSSILSHRWDCSEFEEIEERPRPEFTALAPMTVRNPVTGAEEPYFPEARRLSRTLTGNMVIILMISIVLIFLMAIILYRTILSIIIYRSQSAFFIFSAGRIASLTGSMLNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILKVFIFQFVNFYSSPVYIAFFKGRFVGYPGSYNTLLGIRNEDCGASGCLIELAQELLVIMVGKQVISNIQEFVLPKLKTWWHKRKLKPARSQEVIDEPDTNSQINPWENDYQLLVCEGLFDEYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQFISYLAVISNAFLIAFTSDFLPRLFYRYTAGSMSGYINFTLSVAPANFTQNEMSCRYRGLRDEKGQNTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKREHYMAKEALAENQSLSKSVLE 849

[Close]

BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 697.197 bits (1798), Expect = 0.000e+0
Identity = 357/643 (55.52%), Postives = 484/643 (75.27%), Query Frame = 2

Query:  707 VNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSP---KNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            V EIL    YGRR++ E+G+ R++ D  +  A+PLHEGP++    +  QP++LN RQ+LY YWA + +W +YQPLDHIREYFGEKI  YFAW+G YTAWLLPA+++G  VF+ G+ T   N  AKEIC     + MCPLC+    C+ W + D+C   K+ YLFDHPGT+F+S+FM++WAVTFLEYWKRKNA+LAHHWD +D+ E+EE PR ++AA+    ++NPVTGV EPYFP++ R+ R+LTG + I++M+ VV+IF++ VIIYR ++ + MF+  + +LR  A   AN ++ +VNL LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y   FG+RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE ++PK++ W  + +    ++ Q           +++D +LIP EGL DEYLEIVLQFGFITIFVAAFPLAP FALLNNW+E+RLDA K VCE +RPVAERA+ IGVWF+ILE+++ ++ + NAFL+AFTS+FLP+L Y+Y+F++ L GY N +L++SP    +S+   CRY  +RD +G  K  +WELLAVRLGF+I FEH V  + +++D ++PD+P+ L +KIKRE YLAKQAL D
Sbjct:    1 VYEILARTAYGRRKRAEVGVARLLRDGAFTGAFPLHEGPFKLPSCD-TQPDQLNKRQVLYHYWASWLKWCKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAALVGTCVFVSGILTMGSNTPAKEICESGGLYLMCPLCET---CKPWNMSDICPMAKVGYLFDHPGTVFFSVFMSLWAVTFLEYWKRKNATLAHHWDCMDFHEDEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMFETGSSVLRTQAGNIANISSTLVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLCIIMVGKQLINNIQEFVIPKIKAWRQKRALASVKKAQKTQEPER----WEQDYELIPCEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWVEVRLDAHKFVCEYRRPVAERAQHIGVWFIILEALSHVSVVVNAFLIAFTSDFLPRLLYQYKFNNDLHGYVNFTLAYSPPSYNHSSHTVCRYKAFRDENGKYKLVYWELLAVRLGFIIAFEHVVFFVLRVIDWMVPDIPESLQLKIKRERYLAKQALAD 635

[Close]

BLAST of Anoctamin vs. Ensembl Zebrafish
Match: ano3 (anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3])

HSP 1 Score: 555.829 bits (1431), Expect = 0.000e+0
Identity = 345/832 (41.47%), Postives = 501/832 (60.22%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGK-FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLH----------IP-NIMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPM--FQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFS-KGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLS----WSPKNSTVIP--CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            SG  F DGK +ID+IL +  K+  P  +   R  FE NL+  GL LE++   T     ++KI+ PW+ +C++AE++ +R P +     +D W  KA+              +P N M LD    P     D YT  F ++++H F   NN+ T+FS++ R ++V+ +L+   Y   +      + ++ +  Y++A+P HEG Y+ S+  ++     N R +LYE WAR+G WY+YQPLD IR YFGEKIG YFAW+G YT  L+PA+++G+FVFLYG+FT D +  +KEIC  N +  MCP+C+    C  W L D C++ K+ +LFD+ GT+F++IFMA+WA  FLE+WKR+ A L + WD++D+EEEEE  R Q+ A  S  ++ NP++G  EP+ P   +L R++  +  I  M+++V+  + AV+++R++       FQ   ++ N     +GT   +N ++IM L  VYE +A  LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G PG+Y+  F   R E+C   GCLI+L +Q+ +IMV KQI +N  E+  P LQ W+ R   K  GEQ    S S   L  +  D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  +LE I  +A I+NAF++A TS+++P+  Y  ++             L GY N+SLS       +N +     CRY  YR      + Y     FW +LA RL F+IVFEH V GI   +  +IPD+PK+L  +++RE YL ++ + +A+L
Sbjct:  153 SGLMFRDGKKRIDYILVY--KKSSPQVEK--RCTFERNLRAEGLMLEKEPSLTNSDIMFVKIHAPWDTLCKYAEQMNIRMPFRKKCYFTD-WKKKAMGSRFQLRFRQLKSWLPRNPMKLDKEALPDLVETDCYTAPFCRARMHHFT-INNRETFFSNSTRSRIVHHVLQRTKYEDGKSKMGINR-LLGNSTYEAAFPPHEGCYK-SRHPIKTHGAQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDSSQVSKEICEANTTV-MCPMCEG--NCSSWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGDYNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQIWNNFMELGYPLLQNWWSRRKMKRAGEQ----SNSKEELPQWDRDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAVITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGSYENQYCRYRDYRAPPWSPEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYLMQEMVYEAEL 969

[Close]

BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO4 (major histocompatibility complex class I-related gene protein-like [Source:Xenbase;Acc:XB-GENE-5756215])

HSP 1 Score: 541.962 bits (1395), Expect = 1.096e-179
Identity = 337/819 (41.15%), Postives = 482/819 (58.85%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFD-ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQA-----HPNPSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            SG +FNDGK +ID+IL + +   +       R+ FE N++  GL LE++         ++K++ PWE++ R+AE + +R P +      H        M     L     M LD    P     D YT  F Q +IH F+  NNK T+F++  R ++V+ IL+   Y   +      + ++ +  Y++A+PLHEG Y  SK  ++     N R +L+E WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+I+G+FVFLYG+FT D    ++EIC   N   MCPLCD+   C Y  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G PG Y       R E+C   GCLI+L +Q+ IIMV KQ  +N  E+  P +Q W+ R  + L +  +H     + L  +++D  L P    GL +EYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K + + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++    G          K       RY  YRD     + Y     FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + EK+
Sbjct:   23 SGLFFNDGKRRIDYILVYRKTSLQSEK----REIFERNIRAEGLHLEKESSIVNSDIIFVKLHAPWEVLGRYAELMNVRMPFRRKIYYLHRRYK---FMSRFRGLLPKKPMRLDKEKIPDLEENDCYTAPFSQQRIHHFI-INNKDTFFNNATRTRIVHHILQRVKYEEGKNKIGLNR-LLTNCTYEAAFPLHEGSYR-SKNSIKTHGAENHRHLLFECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLDSCQVSREICQATN-ITMCPLCDKY--CPYMRLSDSCIYAKVTHLFDNSATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERVNPISGKPEPYQAFADKCSRLVVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLL-NLYERVALFLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGRPGAYLRLINKWRLEECHPSGCLIDLCLQMGIIMVLKQTWNNFMELGYPLIQNWWTR--RKLRQ--EHGIHGKTALPQWEKDYNLQPINPYGLFEEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGPCAGQGRA----GEKLIISFSSRYRDYRDPPSAPEPYAYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERVQKEKK 816

[Close]

BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO4 (major histocompatibility complex class I-related gene protein-like [Source:Xenbase;Acc:XB-GENE-5756215])

HSP 1 Score: 536.954 bits (1382), Expect = 9.231e-178
Identity = 336/829 (40.53%), Postives = 486/829 (58.62%), Query Frame = 2

Query:  269 GYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFD-ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQA---HPNPSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLSW-------SPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            G +FNDGK +ID+IL + +   +       R+ FE N++  GL LE++         ++K++ PWE++ R+AE + +R P +    + +    +       L     M LD    P     D YT  F Q +IH F+  NNK T+F++  R ++V+ IL+   Y   +      + ++ +  Y++A+PLHEG Y  SK  ++     N R +L+E WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+I+G+FVFLYG+FT D    ++EIC   N   MCPLCD+   C Y  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G PG Y       R E+C   GCLI+L +Q+ IIMV KQ  +N  E+  P +Q W+ R  + L +  +H     + L  +++D  L P    GL +EYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K + + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++             + GY N SLS        +  NS+  P     Y          FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + EK+
Sbjct:   13 GLFFNDGKRRIDYILVYRKTSLQSEK----REIFERNIRAEGLHLEKESSIVNSDIIFVKLHAPWEVLGRYAELMNVRMPFRRKIYYLHRRYKFMSSRFRGLLPKKPMRLDKEKIPDLEENDCYTAPFSQQRIHHFI-INNKDTFFNNATRTRIVHHILQRVKYEEGKNKIGLNR-LLTNCTYEAAFPLHEGSYR-SKNSIKTHGAENHRHLLFECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAIVGLFVFLYGMFTLDSCQVSREICQATN-ITMCPLCDKY--CPYMRLSDSCIYAKVTHLFDNSATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERVNPISGKPEPYQAFADKCSRLVVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYERVALFLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGRPGAYLRLINKWRLEECHPSGCLIDLCLQMGIIMVLKQTWNNFMELGYPLIQNWWTR--RKLRQ--EHGIHGKTALPQWEKDYNLQPINPYGLFEEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFITQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAVTSDFIPRLVYAYKYGPCAGQGRAGEKCMVGYVNASLSVFLVTDFENHSNSSHPPSAPEPY-----AYTLQFWHVLAARLAFIIVFEHLVFFIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERVQKEKK 819

[Close]

BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 525.783 bits (1353), Expect = 4.029e-173
Identity = 333/828 (40.22%), Postives = 493/828 (59.54%), Query Frame = 2

Query:  275 YFNDGKSKIDFILAWSEKE-KEPHSKALYRKKFESNLKKAGLELE-EDFDET--GKFHYIKIYVPWEIMCRFAEKLALRAPLQAH--PNPSDDWSMKALNCLHIPN-IMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX-XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGN--NSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERP--RAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXX----XXXXXXXPMFQNPLLR--NNAVT---FANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-----LDGYTNHSLSW------------SPKNSTVIPCRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +F DG  +IDF+L+++E   K+   KA  R++FE NL+K+GLELE ED  E+  GK +++KI+ PWE++  +AE L L+ PL+A    + S++     L    +P  +MY +     PD++T  F++ K   F  +  +  +F+ + R+++V  IL    YG     +   IKR++ +  Y  AYPLH+  Y   KT+    E+   R  LY +WA++ R+Y+ QPLD IR+Y+GEKIG YFAW+G YT  L  A+++G F FLYG  T D +IS+KEIC  N      MCPLCD++  C++W L   C   + +++FD+  T+F++IFM +W   FLE+WKR+ A L + WD++D+EEE+++   R +Y + C+  +KNPVT  +EPY P   +  R       +L  + ++I  IIA+I+            M  N  L+  +N +T     + TA+++N V IM L  +YE +A+ +T+ E+ RT  +++N+L  K+FLFQFVN+YSS FY+AFFKG+FVGYP +YSY FG  RNE+C   GCLIEL  QL I+M GKQI  NIQE  VP    W  R       Q  +    + G      D +     GL +EYLE+V+QFGFIT+FVA+FPLAP  ALLNN +EIR+D+ KL  + +RPVA +A  IGVW  IL  I  ++ ++NAF++AFTS+ +P+L Y Y +       + GY   SLS                +  VI CRY  YR   G  K+Y     +W +LA ++ F+I+ EH V  +   +  LIPDVP E+  ++KRE +L ++ L + +L
Sbjct:   22 FFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQEVMYPE-----PDYFTAPFRKDKQELF-RTEEREKFFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHDCQY-WKKTD----ERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCDKR--CEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYSRWEHDG------DLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKILHEYEL 830

[Close]

BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 525.013 bits (1351), Expect = 1.206e-172
Identity = 332/828 (40.10%), Postives = 492/828 (59.42%), Query Frame = 2

Query:  275 YFNDGKSKIDFILAWSEKE-KEPHSKALYRKKFESNLKKAGLELE-EDFDET--GKFHYIKIYVPWEIMCRFAEKLALRAPLQAH--PNPSDDWSMKALNCLHIPN-IMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX-XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGN--NSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERP--RAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXX----XXXXXXXPMFQNPLLR--NNAVT---FANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-----LDGYTNHSLSW------------SPKNSTVIPCRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +F DG  +IDF+L+++E   K+   KA  R++FE NL+K+GLELE ED  E+  GK +++KI+ PWE++  +AE L L+ PL+A    + S++     L    +P  +MY +     PD++T  F++ K      +  +  +F+ + R+++V  IL    YG     +   IKR++ +  Y  AYPLH+  Y   KT+    E+   R  LY +WA++ R+Y+ QPLD IR+Y+GEKIG YFAW+G YT  L  A+++G F FLYG  T D +IS+KEIC  N      MCPLCD++  C++W L   C   + +++FD+  T+F++IFM +W   FLE+WKR+ A L + WD++D+EEE+++   R +Y + C+  +KNPVT  +EPY P   +  R       +L  + ++I  IIA+I+            M  N  L+  +N +T     + TA+++N V IM L  +YE +A+ +T+ E+ RT  +++N+L  K+FLFQFVN+YSS FY+AFFKG+FVGYP +YSY FG  RNE+C   GCLIEL  QL I+M GKQI  NIQE  VP    W  R       Q  +    + G      D +     GL +EYLE+V+QFGFIT+FVA+FPLAP  ALLNN +EIR+D+ KL  + +RPVA +A  IGVW  IL  I  ++ ++NAF++AFTS+ +P+L Y Y +       + GY   SLS                +  VI CRY  YR   G  K+Y     +W +LA ++ F+I+ EH V  +   +  LIPDVP E+  ++KRE +L ++ L + +L
Sbjct:   34 FFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQEVMYPE-----PDYFTAPFRKDK-QELFRTEEREKFFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHDCQY-WKKTD----ERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCDKR--CEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYSRWEHDG------DLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKILHEYEL 842

[Close]

BLAST of Anoctamin vs. Ensembl Xenopus
Match: ANO5 (anoctamin 5 [Source:NCBI gene;Acc:100489787])

HSP 1 Score: 524.628 bits (1350), Expect = 1.958e-172
Identity = 332/828 (40.10%), Postives = 492/828 (59.42%), Query Frame = 2

Query:  275 YFNDGKSKIDFILAWSEKE-KEPHSKALYRKKFESNLKKAGLELE-EDFDET--GKFHYIKIYVPWEIMCRFAEKLALRAPLQAH--PNPSDDWSMKALNCLHIPN-IMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXX-XXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGN--NSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERP--RAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXX----XXXXXXXPMFQNPLLR--NNAVT---FANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-----LDGYTNHSLSW------------SPKNSTVIPCRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +F DG  +IDF+L+++E   K+   KA  R++FE NL+K+GLELE ED  E+  GK +++KI+ PWE++  +AE L L+ PL+A    + S++     L    +P  +MY +     PD++T  F++ K      +  +  +F+ + R+++V  IL    YG     +   IKR++ +  Y  AYPLH+  Y   KT+    E+   R  LY +WA++ R+Y+ QPLD IR+Y+GEKIG YFAW+G YT  L  A+++G F FLYG  T D +IS+KEIC  N      MCPLCD++  C++W L   C   + +++FD+  T+F++IFM +W   FLE+WKR+ A L + WD++D+EEE+++   R +Y + C+  +KNPVT  +EPY P   +  R       +L  + ++I  IIA+I+            M  N  L+  +N +T     + TA+++N V IM L  +YE +A+ +T+ E+ RT  +++N+L  K+FLFQFVN+YSS FY+AFFKG+FVGYP +YSY FG  RNE+C   GCLIEL  QL I+M GKQI  NIQE  VP    W  R       Q  +    + G      D +     GL +EYLE+V+QFGFIT+FVA+FPLAP  ALLNN +EIR+D+ KL  + +RPVA +A  IGVW  IL  I  ++ ++NAF++AFTS+ +P+L Y Y +       + GY   SLS                +  VI CRY  YR   G  K+Y     +W +LA ++ F+I+ EH V  +   +  LIPDVP E+  ++KRE +L ++ L + +L
Sbjct:   34 FFWDGSRRIDFVLSYTEDTGKDAEKKAERRREFELNLQKSGLELETEDKKESENGKTYFVKIHAPWEVLTTYAEVLNLKMPLKADDLKDDSENILSHVLKLFKLPQEVMYPE-----PDYFTAPFRKDK-QELFRTEEREKFFTPSTRNRIVYYILSRCHYGEEEGKKKFGIKRLLTNGSYLDAYPLHDCQY-WKKTD----ERNCERYTLYTHWAKFTRFYKEQPLDLIRKYYGEKIGIYFAWLGFYTEMLFYAAVVGFFCFLYGWITMDDSISSKEICDPNIGGQIIMCPLCDKR--CEFWRLNSTCEPSQYSHMFDNVATLFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYESKCTEKKKNPVTQEMEPYLPATSKAARFCFSGATVLFWIALIIASIIAIIVYRLWVYAAFASIMDNNLALKPVSNLLTPQLATSVTASVLNFVTIMILNFLYERVAIWITDMEIPRTHLEYENRLTMKMFLFQFVNYYSSCFYVAFFKGKFVGYPADYSYLFGKWRNEECDPAGCLIELTTQLTIVMAGKQIWGNIQEAFVPWTWNWLKRRKARNHPQNLYSRWEHDG------DLQTFGGLGLFNEYLEMVVQFGFITLFVASFPLAPLLALLNNILEIRVDSWKLTTQFKRPVAAKAHSIGVWQEILNGIAILSVVTNAFIVAFTSDMIPRLVYYYAYSQDEGTPMSGYIGSSLSVFNVSDFKEQSMPMENDMNVISCRYRDYRYPPGHEKEYQVTMQYWHILAAKMAFIIIMEHVVFLVKFFVAWLIPDVPSEVKARVKREKFLTQKILHEYEL 842

[Close]

BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano7 (anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714])

HSP 1 Score: 758.829 bits (1958), Expect = 0.000e+0
Identity = 398/837 (47.55%), Postives = 549/837 (65.59%), Query Frame = 2

Query:  191 GKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE--------KEKEPHSKALYRKKFESNLKKAGLELEED--FDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTG-----------IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-DSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            G    YG+  +     +  V P        +  K  IDF+L W E         + +  +  ++R+ F  NL  AGL++++    DE    HYI +  PW ++C +AE L L+ PLQ  PN + +WS   L  L IPNI+    P+ PP++Y+C+FK SK+  FLGS+N+ T+F+ST+RHQ++ EIL    YG  +KG  GI +++ + ++ +A+PLH+GP+  +  E  Q   L  RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C  ++SF MCPLC +   C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRKNA+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP++ R+ R+L G           I+C++ ++    +  I V             N  L   A   A+ T ++VNLV I+ L+KVY ++A  LT WEMHRTQ++F++    KVF+FQFVNFY+S  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCL ELA +L +IMVGKQII+N+QEVLVPKL+  + +FS+G        + + +    ++ D +L+P EGL  EYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP++YY +     L G+ N +L+ +P   T      CRY  +RD+DG     +W LLA+RL FVIVFEH V  IG++LDLL+PD+P+ + IK+KRE YLAKQAL + ++
Sbjct:   23 GNGCSYGSTAQASEAGKQQVAPSRVG----SSAKPPIDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFS-AVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSD---CSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRS---------DNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG------KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAENEV 836

[Close]

BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano7 (anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714])

HSP 1 Score: 758.059 bits (1956), Expect = 0.000e+0
Identity = 399/842 (47.39%), Postives = 550/842 (65.32%), Query Frame = 2

Query:  191 GKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE--------KEKEPHSKALYRKKFESNLKKAGLELEED--FDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTG-----------IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-DSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWET 2641
            G    YG+  +     +  V P        +  K  IDF+L W E         + +  +  ++R+ F  NL  AGL++++    DE    HYI +  PW ++C +AE L L+ PLQ  PN + +WS   L  L IPNI+    P+ PP++Y+C+FK SK+  FLGS+N+ T+F+ST+RHQ++ EIL    YG  +KG  GI +++ + ++ +A+PLH+GP+  +  E  Q   L  RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C  ++SF MCPLC +   C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRKNA+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP++ R+ R+L G           I+C++ ++    +  I V             N  L   A   A+ T ++VNLV I+ L+KVY ++A  LT WEMHRTQ++F++    KVF+FQFVNFY+S  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCL ELA +L +IMVGKQII+N+QEVLVPKL+  + +FS+G        + + +    ++ D +L+P EGL  EYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP++YY +     L G+ N +L+ +P   T      CRY  +RD+DG     +W LLA+RL FVIVFEH V  IG++LDLL+PD+P+ + IK+KRE YLAKQAL + + +   T
Sbjct:   23 GNGCSYGSTAQASEAGKQQVAPSRVG----SSAKPPIDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFS-AVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSD---CSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRS---------DNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG------KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAENEALLGAT 841

[Close]

BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano4 (anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344])

HSP 1 Score: 542.347 bits (1396), Expect = 7.319e-179
Identity = 340/851 (39.95%), Postives = 492/851 (57.81%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDE-TGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH----PN-----PSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLS----------------WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            +G YF DGK +ID+IL +  ++  P ++   R+ FE N++  GL++E++         ++K++ PWE++ R+AE++ +R P +      P         D  +           M LD    P     D YT  F Q +IH F+  +NK T+F++  R ++V+ IL+   Y   +      + + +   Y++A+PLHEG Y  SK  ++    +N R +LYE WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+ IG+FVFLYGV T D    +KE+C   +   MCP+CD+   C +  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G+PG Y       R E+C   GCLI+L MQ+ IIMV KQ  +N  E+  P +Q W+ R       + +H +        +++D  L P    GL DEYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++             + GY N SLS                 S  + T +  CRY  YRD    L  Y     FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + E++
Sbjct:   73 NGLYFRDGKCRIDYILVY--RKSNPQTEK--REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKDTFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGS-YEAAFPLHEGSYR-SKNSIKTHGAVNHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATD-IIMCPVCDKY--CPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKV----RQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERLQKERK 906

[Close]

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDE-TGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH----PN-----PSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLS----------------WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            +G YF DGK +ID+IL +  ++  P ++   R+ FE N++  GL++E++         ++K++ PWE++ R+AE++ +R P +      P         D  +           M LD    P     D YT  F Q +IH F+  +NK T+F++  R ++V+ IL+   Y   +      + + +   Y++A+PLHEG Y  SK  ++    +N R +LYE WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+ IG+FVFLYGV T D    +KE+C   +   MCP+CD+   C +  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G+PG Y       R E+C   GCLI+L MQ+ IIMV KQ  +N  E+  P +Q W+ R       + +H +        +++D  L P    GL DEYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++             + GY N SLS                 S  + T +  CRY  YRD    L  Y     FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + E++
Sbjct:   73 NGLYFRDGKCRIDYILVY--RKSNPQTEK--REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKDTFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGS-YEAAFPLHEGSYR-SKNSIKTHGAVNHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATD-IIMCPVCDKY--CPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKV----RQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERLQKERK 906

[Close]

BLAST of Anoctamin vs. Ensembl Mouse
Match: Ano4 (anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344])

HSP 1 Score: 542.732 bits (1397), Expect = 1.273e-178
Identity = 340/851 (39.95%), Postives = 492/851 (57.81%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDE-TGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH----PN-----PSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLS----------------WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            +G YF DGK +ID+IL +  ++  P ++   R+ FE N++  GL++E++         ++K++ PWE++ R+AE++ +R P +      P         D  +           M LD    P     D YT  F Q +IH F+  +NK T+F++  R ++V+ IL+   Y   +      + + +   Y++A+PLHEG Y  SK  ++    +N R +LYE WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+ IG+FVFLYGV T D    +KE+C   +   MCP+CD+   C +  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G+PG Y       R E+C   GCLI+L MQ+ IIMV KQ  +N  E+  P +Q W+ R       + +H +        +++D  L P    GL DEYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++             + GY N SLS                 S  + T +  CRY  YRD    L  Y     FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + E++
Sbjct:  108 NGLYFRDGKCRIDYILVY--RKSNPQTEK--REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKDTFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGS-YEAAFPLHEGSYR-SKNSIKTHGAVNHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATD-IIMCPVCDKY--CPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKV----RQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERLQKERK 941

[Close]

BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q14AT5|ANO7_MOUSE (Anoctamin-7 OS=Mus musculus OX=10090 GN=Ano7 PE=1 SV=2)

HSP 1 Score: 758.059 bits (1956), Expect = 0.000e+0
Identity = 399/842 (47.39%), Postives = 550/842 (65.32%), Query Frame = 2

Query:  191 GKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE--------KEKEPHSKALYRKKFESNLKKAGLELEED--FDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTG-----------IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-DSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWET 2641
            G    YG+  +     +  V P        +  K  IDF+L W E         + +  +  ++R+ F  NL  AGL++++    DE    HYI +  PW ++C +AE L L+ PLQ  PN + +WS   L  L IPNI+    P+ PP++Y+C+FK SK+  FLGS+N+ T+F+ST+RHQ++ EIL    YG  +KG  GI +++ + ++ +A+PLH+GP+  +  E  Q   L  RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C  ++SF MCPLC +   C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRKNA+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP++ R+ R+L G           I+C++ ++    +  I V             N  L   A   A+ T ++VNLV I+ L+KVY ++A  LT WEMHRTQ++F++    KVF+FQFVNFY+S  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCL ELA +L +IMVGKQII+N+QEVLVPKL+  + +FS+G        + + +    ++ D +L+P EGL  EYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP++YY +     L G+ N +L+ +P   T      CRY  +RD+DG     +W LLA+RL FVIVFEH V  IG++LDLL+PD+P+ + IK+KRE YLAKQAL + + +   T
Sbjct:   23 GNGCSYGSTAQASEAGKQQVAPSRVG----SSAKPPIDFVLVWEEDLRNQENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFS-AVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSD---CSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRS---------DNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKFSRG------KKAGTGTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAENEALLGAT 841

[Close]

BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q6IWH7|ANO7_HUMAN (Anoctamin-7 OS=Homo sapiens OX=9606 GN=ANO7 PE=1 SV=2)

HSP 1 Score: 757.288 bits (1954), Expect = 0.000e+0
Identity = 404/835 (48.38%), Postives = 573/835 (68.62%), Query Frame = 2

Query:  194 KANDYGTV---NEEGIEEEAAVPPLAYSGYYFNDGKSKI-DFILAWSEK---EKEPHSKA--------LYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRY-RFDSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            K   YG+    +E G ++ AA      +G   +  K +I DF+L W E    +++  S A         +R+ F  NL+ AGL +++   + G    HY  +   W ++C +AE L L+ PLQ  PN + +WS   L  L IPN++    P+ PP++Y+C F+ +K+ RFLGS+N+ T+F+ST+RHQ++ EIL    YG  +K  +GI +++ + +  +A+PLH+GP++ +  E  Q  +LN RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    +I  +E+C   +SF MCPLC   + C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRK+A+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP+  R  R+L G V I++M+ VV++ ++++I+YR ++ I + +  N LL   A   A+ T ++VNLV I+ L+K+Y  +A  LT WEMHRTQ+ F++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCLIELA +L +IMVGKQ+I+N+QEVL+PKL+ W+ +F +   ++ +  + + +    +++D +L+P EGL DEYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP+ YYR+ R   L G+ N +L+ +P +        CRY  +RD+DG   Q +W LLA+RL FVIVFEH V  +G+LLDLL+PD+P+ + IK+KRE YLAKQAL + +++
Sbjct:   78 KRGSYGSTAHASEPGGQQAAAC----RAG---SPAKPRIADFVLVWEEDLKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFK-TPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLC---LDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKF-RLRSKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAENEVL 900

[Close]

BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q6IFT6|ANO7_RAT (Anoctamin-7 OS=Rattus norvegicus OX=10116 GN=Ano7 PE=2 SV=1)

HSP 1 Score: 753.436 bits (1944), Expect = 0.000e+0
Identity = 395/842 (46.91%), Postives = 545/842 (64.73%), Query Frame = 2

Query:  191 GKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE--------KEKEPHSKALYRKKFESNLKKAGLELEED--FDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTG-----------IVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRY-RFDSLDGYTNHSLSWSPKNSTVI---PCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWET 2641
            G    YG+  +     +  V P        +     IDF+L W E         + +  +  ++R+ F  NL+ AGL++++    DE    HYI +  PW ++C +AE L L+ PLQ  PN + +WS   L  L IPNI+  + P+ PP++Y+C+FK SK+  FLGS+N+ T+F+ST+RHQ++ EIL    YG ++KG  GI +++ + ++ +A+PLH+GP+     E  Q   L  RQ+L+++WAR+G+W +YQPLDH+R YFGEK+  YFAW+G YT WLLPA+++G  VFL G F    ++  +E+C  +++F MCPLC +   C +W L   C   +   LFDH GT+F+S+FMA+WAV  LEYWKRKNA+LA+ WD  DYE+ EERPR Q+AA   +   NP+TG  EPYFP++ R+ R+L G           I+C++ ++    +  I V             N  L   A   A+ T ++VNLV I+ L+KVY I+A  LT WEMHRTQ+ F++    KVF+FQFVNFY+S  YIAFFKGRFVGYPGNY   FG+RNE+C  GGCL ELA +L +IMVGKQII+N+QEVLVPKL+  + +         +  +   +    ++ D +L+P EGL  EYLE+VLQFGF+TIFVAA PLAP FALLNNW+EIRLDA+K VCE +RPVAERA+DIG+WF IL  +T +A ISNAFLLAF+S+FLP++YY + R   L G+ N +L+ +P   T      CRY  +RD+DG     +W LLA+RL FVIVFEH V   G+ LDLL+PD+P+ + IK+KRE YLAKQAL D + +   T
Sbjct:   23 GNGCSYGSTAQASEAGKQQVAPSRVG----SSANPPIDFVLVWEEDLRSRENPTQDKTDTHEIWRETFLENLRVAGLKIDQRDVQDEAAAVHYILLSAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLENVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHQKKGLFGIDQLLAEGVFSAAFPLHDGPFSVVP-ESSQVLGLTQRQVLFKHWARWGKWRKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCSD---CSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSIILYRAVMAIIVSKS---------NNAFLSAWASRIASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTAFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKLCSR-----RKKAGMGANPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTRAPDLRGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLLVPDIPESVEIKVKREYYLAKQALADNEALLGAT 842

[Close]

BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q8C5H1|ANO4_MOUSE (Anoctamin-4 OS=Mus musculus OX=10090 GN=Ano4 PE=1 SV=2)

HSP 1 Score: 542.732 bits (1397), Expect = 8.906e-178
Identity = 340/851 (39.95%), Postives = 492/851 (57.81%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDE-TGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH----PN-----PSDDWSMKALNCLHIPNIMYLDAPNKPP----DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXX--XXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLS----------------WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            +G YF DGK +ID+IL +  ++  P ++   R+ FE N++  GL++E++         ++K++ PWE++ R+AE++ +R P +      P         D  +           M LD    P     D YT  F Q +IH F+  +NK T+F++  R ++V+ IL+   Y   +      + + +   Y++A+PLHEG Y  SK  ++    +N R +LYE WA +G WY+YQPLD +R YFGEKIG YFAW+G YT  L PA+ IG+FVFLYGV T D    +KE+C   +   MCP+CD+   C +  L D C++ K+ +LFD+  T+F+++FMA+WA  FLE+WKR+ A +A+ WD++D+EEEEE  R Q+ A  S  ++ NP++G  EPY     +  R++     I  M+ VVI  +  I +     +     F+  L+RNN+     GTA  +N  +IM L  +YE +AL LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G+PG Y       R E+C   GCLI+L MQ+ IIMV KQ  +N  E+  P +Q W+ R       + +H +        +++D  L P    GL DEYLE++LQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+A RAKDIG+W+ ILE I  ++ I+NAF++A TS+F+P+L Y Y++             + GY N SLS                 S  + T +  CRY  YRD    L  Y     FW +LA RL F+IVFEH V  I  L+  LIPD+PK+L  +++RE YL ++ + +A+L   E  + E++
Sbjct:  108 NGLYFRDGKCRIDYILVY--RKSNPQTEK--REVFERNIRAEGLQMEKESSLINSDIIFVKLHAPWEVLGRYAEQMNVRMPFRRKIYYLPRRYKFMSRIDKQISRFRRWLPKKPMRLDKETLPDLEENDCYTAPFSQQRIHHFI-IHNKDTFFNNATRSRIVHHILQRIKYEEGKNKIGLNRLLTNGS-YEAAFPLHEGSYR-SKNSIKTHGAVNHRHLLYECWASWGVWYKYQPLDLVRRYFGEKIGLYFAWLGWYTGMLFPAAFIGLFVFLYGVTTLDHCQVSKEVCQATD-IIMCPVCDKY--CPFMRLSDSCVYAKVTHLFDNGATVFFAVFMAVWATVFLEFWKRRRAVIAYDWDLIDWEEEEEEIRPQFEAKYSKKERMNPISGKPEPYQAFTDKCSRLIVSASGIFFMICVVIAAVFGIVIYRVVTVSTFAAFKWALIRNNSQVATTGTAVCINFCIIMLLNVLYEKVALLLTNLEQPRTESEWENSFTLKMFLFQFVNLNSSTFYIAFFLGRFTGHPGAYLRLINRWRLEECHPSGCLIDLCMQMGIIMVLKQTWNNFMELGYPLIQNWWTRRKV----RQEHGTERKINFPQWEKDYNLQPMNAYGLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDIGIWYGILEGIGILSVITNAFVIAITSDFIPRLVYAYKYGPCAGQGEAGQKCMVGYVNASLSVFRISDFENRSEPESDGSEFSGTPLKYCRYRDYRDPPHSLAPYGYTLQFWHVLAARLAFIIVFEHLVFCIKHLISYLIPDLPKDLRDRMRREKYLIQEMMYEAEL---ERLQKERK 941

[Close]

BLAST of Anoctamin vs. UniProt/SwissProt
Match: sp|Q9BYT9|ANO3_HUMAN (Anoctamin-3 OS=Homo sapiens OX=9606 GN=ANO3 PE=1 SV=2)

HSP 1 Score: 541.962 bits (1395), Expect = 3.452e-177
Identity = 347/834 (41.61%), Postives = 498/834 (59.71%), Query Frame = 2

Query:  257 LAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE-EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWS---------MKALNCLHIPNIMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSK-TELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQ-KNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVT----FANGTAAI-VNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-----------DSLDGYTNHSLSWSPKNSTVIP----CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            +A SG  F DGK +ID+IL +    ++ + +   R  FE NL+  GL LE E    +    +IKI++PW+ +C++AE+L +R P +     +D  S          + +      N M LD    P     D YT  F +++IH F+  NNK T+FS+  R ++V  +LE   Y          K ++++  Y +A+P HEG Y+ S+  +   P+  N+R +LYE WAR+G WY++QPLD IR YFGEKIG YFAW+G YT  L+PA+I+G+ VF YG+FT + +  ++EIC     F MCPLCD+   C    L D C++ K+ YLFD+ GT+F++IFMA+WA  FLE+WKR+ + L + WD++++EEEEE  R Q+ A     +  NP+TG  EP+ P   ++ R+L  +  I  M+++VI  +  V++YR+++   M Q    + N +     FA   AA+ +N ++IM L   YE IA  LT  E  RT+S+++N    K+FLFQFVN  SSIFYIAFF GRFVG+PG Y+  F   R E+C   GCLI+L +Q+ +IM  KQI +N  E+  P +Q W+ R     G    HD    + +  ++ D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  ILE I  +A I+NAF++A TS+++P+  Y Y++           + L GY N+SLS+   +   +     CRY  YR      K Y     +W +LA RL F+IVFEH V GI   +  LIPDVPK L+ +I+RE YL ++ + +A+L
Sbjct:  150 IASSGPLFKDGKKRIDYILVY----RKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSMGRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFI-INNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRK-LINNGSYIAAFPPHEGAYKSSQPIKTHGPQ--NNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVF-MCPLCDK--NCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVV---MEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRG---IHD----ASIPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAEL 962

[Close]

BLAST of Anoctamin vs. TrEMBL
Match: A0A267GKF1 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021551g2 PE=3 SV=1)

HSP 1 Score: 985.326 bits (2546), Expect = 0.000e+0
Identity = 517/804 (64.30%), Postives = 647/804 (80.47%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEK----EKEP-----HSKALYRKKFESNLKKAGLELEEDFD--ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGL----GEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            SG YF DG  ++DF++ W E     + +P       KA+YR++FE NL+K G+++EE+    E  K H+IK++VPW++MC +AE L LRAPLQAH +P+D+WS K L  LHIPN+M    PN+P D+YTC F++SK+ +FLGS+++ TYFSSTQRHQV  EIL TQ+YG+R++ E+GI R++++E+Y  A+PLHEGPYE  K    QPE LN+RQIL  YWA++G WY+YQPLDHIREY+GEKIG YFAW+GLYTAWLLPASI+GI VFLYG FTF  N+   E+C  N ++ MCPLCDE IGC+YW L D+CMF++I+YLFDHPGT+FYS+F+A WAVTFLE WKRKNASLAHHWDV+D+EE+EERPR +Y+ALCS +++NPVTG +EP+FP   R+PRI+TGI CI++MM +V+IFIIAVIIYRVLI IP+FQNPLLR+ A T A+G+AAIVNL+LIM L KVYE +A KLT+WEMHRTQ++F++QLI KVF+FQFVNFYSSIFYIAFFKG+F GYPG Y  FFGLRNE+C NGGCLIELA QLA+IM+GKQII+N QEV +PKL TW +RF+KGL     ++ +   C        + D +LIPYEGL +EYLE+VLQFGFITIFVAAFPLAPFFALLNNW+EIRLDA KLVCET+RPV+ERA+DIGVWF +L+ I  ++ ISNAFL+AFTSEFLPK  Y+Y+FDS L GYTN +L+WSP NST  PCRY  +R  DG    ++W+LLAVRL FVIVFEH V  I ++LD+LIPDVP+ L +KIKRE YLAKQAL DA+ +
Sbjct:   64 SGCYFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNVMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDY--QPEDLNARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCESNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGKYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLNWSRSQEAEASRC--------QADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETL 857

[Close]

BLAST of Anoctamin vs. TrEMBL
Match: A0A267H1A6 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig021551g3 PE=3 SV=1)

HSP 1 Score: 984.941 bits (2545), Expect = 0.000e+0
Identity = 517/804 (64.30%), Postives = 647/804 (80.47%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEK----EKEP-----HSKALYRKKFESNLKKAGLELEEDFD--ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGL----GEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            SG YF DG  ++DF++ W E     + +P       KA+YR++FE NL+K G+++EE+    E  K H+IK++VPW++MC +AE L LRAPLQAH +P+D+WS K L  LHIPN+M    PN+P D+YTC F++SK+ +FLGS+++ TYFSSTQRHQV  EIL TQ+YG+R++ E+GI R++++E+Y  A+PLHEGPYE  K    QPE LN+RQIL  YWA++G WY+YQPLDHIREY+GEKIG YFAW+GLYTAWLLPASI+GI VFLYG FTF  N+   E+C  N ++ MCPLCDE IGC+YW L D+CMF++I+YLFDHPGT+FYS+F+A WAVTFLE WKRKNASLAHHWDV+D+EE+EERPR +Y+ALCS +++NPVTG +EP+FP   R+PRI+TGI CI++MM +V+IFIIAVIIYRVLI IP+FQNPLLR+ A T A+G+AAIVNL+LIM L KVYE +A KLT+WEMHRTQ++F++QLI KVF+FQFVNFYSSIFYIAFFKG+F GYPG Y  FFGLRNE+C NGGCLIELA QLA+IM+GKQII+N QEV +PKL TW +RF+KGL     ++ +   C        + D +LIPYEGL +EYLE+VLQFGFITIFVAAFPLAPFFALLNNW+EIRLDA KLVCET+RPV+ERA+DIGVWF +L+ I  ++ ISNAFL+AFTSEFLPK  Y+Y+FDS L GYTN +L+WSP NST  PCRY  +R  DG    ++W+LLAVRL FVIVFEH V  I ++LD+LIPDVP+ L +KIKRE YLAKQAL DA+ +
Sbjct:   64 SGCYFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNVMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDY--QPEDLNARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCDSNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGRYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLNWSRSQEAEASRC--------QADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETL 857

[Close]

BLAST of Anoctamin vs. TrEMBL
Match: A0A267FA31 (Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006611g1 PE=3 SV=1)

HSP 1 Score: 983.015 bits (2540), Expect = 0.000e+0
Identity = 517/804 (64.30%), Postives = 646/804 (80.35%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEK----EKEP-----HSKALYRKKFESNLKKAGLELEEDFD--ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGL----GEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            SG YF DG  ++DF++ W E     + +P       KA+YR++FE NL+K G+++EE+    E  K H+IK++VPW++MC +AE L LRAPLQAH +P+D+WS K L  LHIPN M    PN+P D+YTC F++SK+ +FLGS+++ TYFSSTQRHQV  EIL TQ+YG+R++ E+GI R++++E+Y  A+PLHEGPYE  K    QPE LN+RQIL  YWA++G WY+YQPLDHIREY+GEKIG YFAW+GLYTAWLLPASI+GI VFLYG FTF  N+   E+C  N ++ MCPLCDE IGC+YW L D+CMF++I+YLFDHPGT+FYS+F+A WAVTFLE WKRKNASLAHHWDV+D+EE+EERPR +Y+ALCS +++NPVTG +EP+FP   R+PRI+TGI CI++MM +V+IFIIAVIIYRVLI IP+FQNPLLR+ A T A+G+AAIVNL+LIM L KVYE +A KLT+WEMHRTQ++F++QLI KVF+FQFVNFYSSIFYIAFFKG+F GYPG Y  FFGLRNE+C NGGCLIELA QLA+IM+GKQII+N QEV +PKL TW +RF+KGL     ++ +   C        + D +LIPYEGL +EYLE+VLQFGFITIFVAAFPLAPFFALLNNW+EIRLDA KLVCET+RPV+ERA+DIGVWF +L+ I  ++ ISNAFL+AFTSEFLPK  Y+Y+FDS L GYTN +L+WSP NST  PCRY  +R  DG    ++W+LLAVRL FVIVFEH V  I ++LD+LIPDVP+ L +KIKRE YLAKQAL DA+ +
Sbjct:   64 SGCYFADGVRRVDFVIVWEEDLQRADDDPEDPWEQRKAVYRRRFEGNLRKVGVQMEEETSTSEKKKIHFIKLFVPWDVMCYYAEDLCLRAPLQAHSHPADNWSGKVLKSLHIPNAMEQRVPNQPLDYYTCPFRKSKLSKFLGSDDQDTYFSSTQRHQVAYEILATQVYGKRKRAEVGIDRLLEEEVYSGAFPLHEGPYELPKDY--QPEDLNARQILNAYWAKWGLWYKYQPLDHIREYYGEKIGLYFAWLGLYTAWLLPASIVGIIVFLYGCFTFKANVPGNEVCDSNMTYKMCPLCDEAIGCKYWYLSDICMFMRISYLFDHPGTVFYSVFVAFWAVTFLENWKRKNASLAHHWDVMDFEEDEERPRPEYSALCSSYERNPVTGNLEPHFPNSLRIPRIITGITCIIIMMVIVVIFIIAVIIYRVLIAIPLFQNPLLRSQASTVASGSAAIVNLILIMSLGKVYEKLAYKLTQWEMHRTQTEFEDQLILKVFIFQFVNFYSSIFYIAFFKGKFTGYPGRYIKFFGLRNEECDNGGCLIELAQQLAVIMIGKQIINNCQEVFLPKLFTWIHRFTKGLNWSRSQEAEASRC--------QADYQLIPYEGLFEEYLEMVLQFGFITIFVAAFPLAPFFALLNNWLEIRLDASKLVCETRRPVSERAQDIGVWFTLLDVIVQLSVISNAFLIAFTSEFLPKELYKYQFDSELHGYTNFTLAWSPANSTAQPCRYKAFRGEDGHYTMFYWKLLAVRLAFVIVFEHVVFFISRMLDILIPDVPEVLQVKIKREQYLAKQALMDAETL 857

[Close]

BLAST of Anoctamin vs. TrEMBL
Match: A0A4E0RHA9 (Anoctamin OS=Fasciola hepatica OX=6192 GN=D915_002627 PE=3 SV=1)

HSP 1 Score: 979.934 bits (2532), Expect = 0.000e+0
Identity = 489/803 (60.90%), Postives = 632/803 (78.70%), Query Frame = 2

Query:  251 PPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKA-------LYRKKFESNLKKAGLELEEDF--DETGKFHYIKIYVPWEIMCRFAEKLALRAPLQ-AHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            PP    GYYFNDG  KID++L W +   E  + +        YR +F  NL+K G+E EE+    +  + HY+K+++ W++MC +AE L+LRAPLQ +  N   +WS   L+ LHIPNIM  D PN P D+YTC+F++SK+ RFLGS ++ TYF+STQR QV  EIL TQ YG R+K ++GI R++++ +Y +AY +HEGPY+ +K +L+ PEK+N+RQILY YWAR+G WY+YQPLDHIR+Y+GEKIGFYFAW+GLYTAWLLPA+++GI VFLYG+ T + +I A+E C+ +    MCPLC+E +GCQYW L+D+C ++K +YLFDHPGT+FY+IF+ +W VTFLEYWKRKNA LAH WDVLDYE EEERPR QY ALCS F KNP+TG +EP+FP+  R+ R++ G++CILLMM +V++FI+AVIIYR+LI +P+F+N LLR NA  +AN +AA+VNLVLIMCL KVYE +A K+T+WEMHRTQS F+NQL FKVFLFQFVNFY+SIFY+AFFKGRF+GYPG+Y YFFGLRNEDC NGGCLIELA QL +IMVGKQII+N QE+++PKL+TW+++++KGL +Q    + S     ++ ED KLIPYEGL +EYLE+VLQFGF+TIFVAAFPLAPFFALLNNW+EIRLDA KLV ET+RP++ERA++IGVWF ILE +  IA ISNAF++AFTS+FLPKL Y+Y  +  L G+TN +L+WSP NST + CRYP +RDN+G    ++W LLA+RL FVI+FEH    +  L D LIPDVP  L  +I+RE +LAKQAL D  L
Sbjct:   50 PP----GYYFNDGLRKIDYVLVWEDTNSEESNSSKVTRVHRRYRTRFVENLQKLGVETEEEIYHGQMLRTHYLKLHITWDLMCHYAEMLSLRAPLQKSAANRRTNWSASLLSTLHIPNIMQQDVPNHPTDYYTCQFRKSKLERFLGSGDRATYFTSTQRQQVACEILSTQAYGSRKKAQVGIDRLIEEGVYSAAYVIHEGPYQVTKEDLKHPEKMNARQILYWYWARWGCWYRYQPLDHIRQYYGEKIGFYFAWLGLYTAWLLPAAVVGILVFLYGLVTMNDSIPAQEACSRDTR--MCPLCEESLGCQYWNLRDMCFYLKASYLFDHPGTVFYAIFIVIWGVTFLEYWKRKNAKLAHRWDVLDYEIEEERPRPQYTALCSDFAKNPITGALEPHFPERLRMARVVAGLICILLMMVLVMVFIVAVIIYRLLIMVPLFKNELLRPNAGIYANMSAAMVNLVLIMCLGKVYEKLAYKMTQWEMHRTQSIFENQLTFKVFLFQFVNFYASIFYVAFFKGRFIGYPGHYVYFFGLRNEDCNNGGCLIELAQQLLVIMVGKQIINNCQEIIIPKLRTWWHKYTKGLNKQCIGSTNSLQIECMFMEDYKLIPYEGLFEEYLEMVLQFGFVTIFVAAFPLAPFFALLNNWIEIRLDANKLVRETRRPLSERAQNIGVWFRILEVLVRIAVISNAFIIAFTSQFLPKLLYQYEINQDLRGFTNFTLAWSPPNSTRLDCRYPAFRDNNGEYTMFYWRLLALRLVFVILFEHVAFLLADLFDFLIPDVPSSLAERIQRERFLAKQALLDVHL 846

[Close]

BLAST of Anoctamin vs. TrEMBL
Match: A0A504YTV8 (Anoctamin OS=Fasciola gigantica OX=46835 GN=FGIG_00855 PE=3 SV=1)

HSP 1 Score: 974.926 bits (2519), Expect = 0.000e+0
Identity = 489/808 (60.52%), Postives = 630/808 (77.97%), Query Frame = 2

Query:  251 PPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKA-------LYRKKFESNLKKAGLELEEDF--DETGKFHYIKIYVPWEIMCRFAEKLALRAPLQ-AHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWET 2641
            PP    GYYFNDG  KID++L W +   E  + +        YR +F  NL+K G+E EE+    +  + HY+K+++ W++MC +AE L+LRAPLQ +  N   +WS   L+ LHIPNIM  D PN P D+YTC+F++SK+ RFLGS ++ TYF+STQR QV  EIL TQ YG R K ++GI R++++ +Y +AY +HEGPY+ +  EL+ PEK+N+RQILY YWAR+G WY+YQPLDHIR+Y+GEKIGFYFAW+GLYTAWLLPA+++GI VFLYG+ T + +I A+E C+ +    MCPLC+E +GCQYW L+D+C ++K +YLFDHPGT+FY+IF+ +W VTFLEYWKRKNA LAH WDVLDYE EEERPR QY ALCS F KNP+TG +EP+FP+  R+ R++ G++CILLMM +V++FI+AVIIYR+LI +P+F+N LLR NA  +AN +AA+VNLVLIM L KVYE +A K+T+WEMHRTQS F+NQL FKVFLFQFVNFY+SIFY+AFFKGRF+GYPG+Y YFFGLRNEDC NGGCLIELA QL +IMVGKQII+N QE+++PKL+TW+++++KGL  Q    + S     ++ ED KLIPYEGL +EYLE+VLQFGF+TIFVAAFPLAPFFALLNNW+EIRLDA KLV ET+RP++ERA++IGVWF ILE +  IA ISNAF++AFTS+FLPKL Y+Y  +  L G+TN +L+WSP NST + CRYP +RDN+G    ++W LLA+RL FVI+FEH    +  L D LIPDVP  L  +I+RE +LAKQAL D  L  + T
Sbjct:   31 PP----GYYFNDGLRKIDYVLVWEDTNSEESNSSKVTRVHRRYRTRFVENLQKLGVETEEEIRHGQMLRTHYLKLHITWDLMCHYAEMLSLRAPLQKSTANRRTNWSATLLSTLHIPNIMQQDVPNHPTDYYTCQFRKSKLERFLGSGDRATYFTSTQRQQVACEILSTQAYGSREKAQVGIDRLIEEGVYSAAYVIHEGPYQVTMEELKHPEKMNARQILYWYWARWGCWYRYQPLDHIRQYYGEKIGFYFAWLGLYTAWLLPAAVVGILVFLYGLTTMNDSIPAQEACSTDTR--MCPLCEESLGCQYWNLRDMCFYLKASYLFDHPGTVFYAIFIVIWGVTFLEYWKRKNAKLAHRWDVLDYEIEEERPRPQYTALCSDFAKNPITGALEPHFPERLRMARVVAGLICILLMMVLVMVFIVAVIIYRLLIMVPLFKNELLRPNAGIYANMSAAMVNLVLIMFLGKVYEKLAYKMTQWEMHRTQSIFENQLTFKVFLFQFVNFYASIFYVAFFKGRFIGYPGHYVYFFGLRNEDCNNGGCLIELAQQLLVIMVGKQIINNCQEIIIPKLRTWWHKYTKGLNRQCIGSTNSLQTGCMFMEDYKLIPYEGLFEEYLEMVLQFGFVTIFVAAFPLAPFFALLNNWIEIRLDANKLVRETRRPLSERAQNIGVWFRILEVLVRIAVISNAFIIAFTSQFLPKLLYQYEINQDLRGFTNFTLAWSPPNSTRLDCRYPAFRDNNGEYTMFYWRLLALRLIFVILFEHVAFLLADLFDFLIPDVPSSLTERIQRERFLAKQALLDVHLDRYST 832

[Close]

BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano11 (anoctamin-7 [Source:NCBI gene;Acc:103029593])

HSP 1 Score: 817.379 bits (2110), Expect = 0.000e+0
Identity = 428/823 (52.00%), Postives = 587/823 (71.32%), Query Frame = 2

Query:  269 GYYFNDGKSKIDFILAW------------------------------SEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGL--IIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKN---STVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            G YF DG++KID++L W                              S  EK     A +R +F  N++ AGL LE++   + K   HY+K+  PW+++  +AE+L LRAPLQA P+P  + S + L  L +PN+M    PN+P D+YTC F++SK+ +FLGS +   YFS TQRH++V EIL   +YG+R+  E+G  R++++  + +A+PLHEGP+E    E+  P++LN RQILY YWAR+ +WY+YQPLDHIREYFGEKI  YFAW+G YTAWLLPA+I+G FVF+ G+ T   N  AKEIC     + MCPLC+    C+ W + D+C   ++ YLFDHPGT+F+S+FM+ WAVTFLEYWKRKNA+LAHHWD +D+ EEEE PR ++AA+    ++NPVTGV EPYFP++ R+ R+LTG + I++M+ VV+IF++ VIIYR ++ + M++  + +LR  A   AN ++++VNL LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y   FG+RNEDC  GGCLIELA QL IIM+GKQ+I+N+QE ++PK++ W  R  K L    +    +  GL    +++D +L+  EGL DEYLEIVLQFGFITIFVAAFPLAP FALLNNW E+RLDA K VCE +RPVAERA++IGVWF+ILE+++ ++ I NAFL+AFTS+FLP+L YRY+F+S L GY N +L+++P +   S+   CRY  +RD +G     +WELLAVRLGF+I FEH V  + +++D ++PDVP+ L +K+KRE YLAKQAL D
Sbjct:   73 GNYFRDGQTKIDYVLVWEIKSRRKRRAQGKGRGEAEDEEELQAAQEESRSEKRKAQVARWRDRFIQNIQSAGLLLEKEETSSAKKTIHYLKLSAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWMPNVMADFVPNRPVDYYTCAFRKSKMEKFLGSEDHQNYFSITQRHRIVYEILARTVYGKRKHAEVGAARLLNEGAFKAAFPLHEGPFELPDYEI-SPDQLNKRQILYHYWARWSKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTFVFVSGIMTMGSNTPAKEICESGGHYLMCPLCET---CKPWNMSDICPMAQVGYLFDHPGTVFFSVFMSFWAVTFLEYWKRKNATLAHHWDCMDFHEEEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMYETGSSVLRTQAGNIANISSSMVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLFIIMIGKQLINNVQEFVIPKVKAW--RQKKALASVKK----AQGGLEPQRWEQDYELVACEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWAEVRLDAHKFVCEYRRPVAERAQNIGVWFIILEALSHVSVIVNAFLIAFTSDFLPRLLYRYKFNSDLHGYVNFTLAYAPPSYNYSSHGMCRYKAFRDENGSYTLVYWELLAVRLGFIIAFEHVVFSVLRVIDWMVPDVPESLELKVKRERYLAKQALAD 885

[Close]

BLAST of Anoctamin vs. Ensembl Cavefish
Match: ano11 (anoctamin-7 [Source:NCBI gene;Acc:103029593])

HSP 1 Score: 772.696 bits (1994), Expect = 0.000e+0
Identity = 408/788 (51.78%), Postives = 558/788 (70.81%), Query Frame = 2

Query:  269 GYYFNDGKSKIDFILAW------------------------------SEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGK--FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGL--IIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKN---STVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTV 2512
            G YF DG++KID++L W                              S  EK     A +R +F  N++ AGL LE++   + K   HY+K+  PW+++  +AE+L LRAPLQA P+P  + S + L  L +PN+M    PN+P D+YTC F++SK+ +FLGS +   YFS TQRH++V EIL   +YG+R+  E+G  R++++  + +A+PLHEGP+E    E+  P++LN RQILY YWAR+ +WY+YQPLDHIREYFGEKI  YFAW+G YTAWLLPA+I+G FVF+ G+ T   N  AKEIC     + MCPLC+    C+ W + D+C   ++ YLFDHPGT+F+S+FM+ WAVTFLEYWKRKNA+LAHHWD +D+ EEEE PR ++AA+    ++NPVTGV EPYFP++ R+ R+LTG + I++M+ VV+IF++ VIIYR ++ + M++  + +LR  A   AN ++++VNL LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y   FG+RNEDC  GGCLIELA QL IIM+GKQ+I+N+QE ++PK++ W  R  K L    +    +  GL    +++D +L+  EGL DEYLEIVLQFGFITIFVAAFPLAP FALLNNW E+RLDA K VCE +RPVAERA++IGVWF+ILE+++ ++ I NAFL+AFTS+FLP+L YRY+F+S L GY N +L+++P +   S+   CRY  +RD +G     +WELLAVRLGF+I FE   
Sbjct:   73 GNYFRDGQTKIDYVLVWEIKSRRKRRAQGKGRGEAEDEEELQAAQEESRSEKRKAQVARWRDRFIQNIQSAGLLLEKEETSSAKKTIHYLKLSAPWDVLVYYAEELCLRAPLQAQPHPDFNTSARVLQKLWMPNVMADFVPNRPVDYYTCAFRKSKMEKFLGSEDHQNYFSITQRHRIVYEILARTVYGKRKHAEVGAARLLNEGAFKAAFPLHEGPFELPDYEI-SPDQLNKRQILYHYWARWSKWYKYQPLDHIREYFGEKIALYFAWLGFYTAWLLPAAIVGTFVFVSGIMTMGSNTPAKEICESGGHYLMCPLCET---CKPWNMSDICPMAQVGYLFDHPGTVFFSVFMSFWAVTFLEYWKRKNATLAHHWDCMDFHEEEEPPRPEFAAMAPAMEENPVTGVKEPYFPEKARISRMLTGSMVIVIMLCVVMIFLVTVIIYRSIVSVMMYETGSSVLRTQAGNIANISSSMVNLALILLMGQVYTALAEQLTKWEMHRTQTQYEDAFTFKVFIFQFVNFYSSPFYVAFFKGRFVGYPGHYGTLFGMRNEDCGPGGCLIELAEQLFIIMIGKQLINNVQEFVIPKVKAW--RQKKALASVKK----AQGGLEPQRWEQDYELVACEGLFDEYLEIVLQFGFITIFVAAFPLAPLFALLNNWAEVRLDAHKFVCEYRRPVAERAQNIGVWFIILEALSHVSVIVNAFLIAFTSDFLPRLLYRYKFNSDLHGYVNFTLAYAPPSYNYSSHGMCRYKAFRDENGSYTLVYWELLAVRLGFIIAFEQAT 850

[Close]

BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 743.036 bits (1917), Expect = 0.000e+0
Identity = 412/824 (50.00%), Postives = 571/824 (69.30%), Query Frame = 2

Query:  203 DYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE-----KEKEPHSKAL-------YRKKFESNLKKAGLELE--EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTV--IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            +YGT++  G  ++            F+DG ++IDF+L W E     K  EP  K         +R++F S L+ AGL+ E  E      K  Y+ +  PW I+C +AE+++LR PLQ   N   +WS K L+ LHIPNI+    PN PPD+YTC+F   K+ RFL   NK T+F +TQRHQ++ EIL    YG  ++GE+GI R++ +  + +AYPLHEGPY   +     PE L++RQILY+YWAR+  W +YQPL HIREYFGEK+  YFAW+G YT WLLPA+++G F+ L+G++    ++ A+E+C    +  MCPLCD    C YW L  +C   ++  LFD+ GT+F+SIFM++WAVTFLE+WKR  A L+H WD  ++EE EERPR ++AA+     +NPVTG  EP+FP+  R  RI+TG + I++M+ VV+IF+IA+I+YR ++ I +++  N     +A   A+ T +++NLV+I+ L+KVY  +A  LT WEMHRTQ+ +++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNEDC   GCLIELA +L +IMVGKQ+I+N+QE ++PK++ W+ +  K    Q ++ +     +  ++ D +L+  EGL  EYLE+VLQFGFITIFVAA PLAPFFAL+NNW+EIRLD+QK VCE +RPVAERA+DIG+WF IL+ IT +A ISNAFL+AFTS+FLP+LYYRY  + SL GY + +LS +P N T   + CRY G+RD+ G     ++ LLA+RLGFVI+FEH V  IG+++D ++PD+P+E+ IKIKRE Y+AK+AL +
Sbjct:   24 NYGTIDGSGAPQK--------DRNVFSDGVTRIDFVLVWDEPVTPLKASEPEDKTSTQATHRKWREEFLSKLQTAGLQQEQKEVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGP-AGPESLSTRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIFLIAIILYRSILSIIIYKSHNAFFIFSAGRIASLTGSVLNLVVILLLSKVYTYLAQILTRWEMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKIKAWWNK-RKLHPTQRENGANITENVAPWETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFEHVVFLIGRMIDWMVPDIPEEVEIKIKREQYMAKKALAE 834

[Close]

BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 702.975 bits (1813), Expect = 0.000e+0
Identity = 390/780 (50.00%), Postives = 542/780 (69.49%), Query Frame = 2

Query:  311 LAWSEKEKEPHSKALYRK---KFESNLKKAGLELEEDFDET-GKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTV--IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLI 2629
            L  SE E +  ++A +RK   +F S L+ AGL+ E+   ++  K  Y+ +  PW I+C +AE+++LR PLQ   N   +WS K L+ LHIPNI+    PN PPD+YTC+F   K+ RFL   NK T+F +TQRHQ++ EIL    YG  ++GE+GI R++ +  + +AYPLHEGPY   +     PE L++RQILY+YWAR+  W +YQPL HIREYFGEK+  YFAW+G YT WLLPA+++G F+ L+G++    ++ A+E+C    +  MCPLCD    C YW L  +C   ++  LFD+ GT+F+SIFM++WAVTFLE+WKR  A L+H WD  ++EE EERPR ++AA+     +NPVTG  EP+FP+  R  RI+TG + I++M+ VV+IF+IA+I+YR ++ I ++++    +NA         I ++  ++  ++ Y    L+ T  EMHRTQ+ +++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNEDC   GCLIELA +L +IMVGKQ+I+N+QE ++PKL             Q ++ +     +  ++ D +L+  EGL  EYLE+VLQFGFITIFVAA PLAPFFAL+NNW+EIRLD+QK VCE +RPVAERA+DIG+WF IL+ IT +A ISNAFL+AFTS+FLP+LYYRY  + SL GY + +LS +P N T   + CRY G+RD+ G     ++ LLA+RLGFVI+FEH V  IG+++D ++PD+P+E+ IKIKRE Y+AK+AL +  +I
Sbjct:    6 LKASEPEDKTSTQATHRKWREEFLSKLQTAGLQQEQVVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGP-AGPESLSTRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIFLIAIILYRSILSIIIYKS----HNAF-------FIFSMCFLIVQSQRY-FFTLRPT--EMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKLHP----------TQRENGANITENVAPWETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFEHVVFLIGRMIDWMVPDIPEEVEIKIKREQYMAKKALAENQVI 757

[Close]

BLAST of Anoctamin vs. Ensembl Cavefish
Match: si:dkey-83h2.5 (anoctamin-7-like [Source:NCBI gene;Acc:103022406])

HSP 1 Score: 699.893 bits (1805), Expect = 0.000e+0
Identity = 393/791 (49.68%), Postives = 542/791 (68.52%), Query Frame = 2

Query:  203 DYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSE-----KEKEPHSKAL-------YRKKFESNLKKAGLELE--EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTV--IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAG 2518
            +YGT++  G  ++            F+DG ++IDF+L W E     K  EP  K         +R++F S L+ AGL+ E  E      K  Y+ +  PW I+C +AE+++LR PLQ   N   +WS K L+ LHIPNI+    PN PPD+YTC+F   K+ RFL   NK T+F +TQRHQ++ EIL    YG  ++GE+GI R++ +  + +AYPLHEGPY   +     PE L++RQILY+YWAR+  W +YQPL HIREYFGEK+  YFAW+G YT WLLPA+++G F+ L+G++    ++ A+E+C    +  MCPLCD    C YW L  +C   ++  LFD+ GT+F+SIFM++WAVTFLE+WKR  A L+H WD  ++EE EERPR ++AA+     +NPVTG  EP+FP+  R  RI+TG + I++M+ VV+IF+IA+I+YR ++ I +++  N     +A   A+ T +++NLV+I+ L+KVY  +A  LT WEMHRTQ+ +++    KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNEDC   GCLIELA +L +IMVGKQ+I+N+QE ++PK++ W+ +  K    Q ++ +     +  ++ D +L+  EGL  EYLE+VLQFGFITIFVAA PLAPFFAL+NNW+EIRLD+QK VCE +RPVAERA+DIG+WF IL+ IT +A ISNAFL+AFTS+FLP+LYYRY  + SL GY + +LS +P N T   + CRY G+RD+ G     ++ LLA+RLGFVI+FE +  G
Sbjct:   24 NYGTIDGSGAPQK--------DRNVFSDGVTRIDFVLVWDEPVTPLKASEPEDKTSTQATHRKWREEFLSKLQTAGLQQEQKEVVQSKTKTTYVLLSAPWNILCYYAEEISLRVPLQVETNEDSNWSEKILHKLHIPNILAQQVPNPPPDYYTCQFHTKKLERFLDHENKDTFFKTTQRHQILYEILSRTPYGAMKRGEVGIARLITEGAFTAAYPLHEGPYHMPRGP-AGPESLSTRQILYQYWARWACWKKYQPLHHIREYFGEKVALYFAWLGFYTGWLLPAAVVGFFLSLFGIWLMVTDVPAQEVCHNGENIVMCPLCDI---CSYWNLSSICTTFRVGLLFDNGGTVFFSIFMSLWAVTFLEHWKRTCAVLSHRWDCSEFEESEERPRPEFAAMAPTTIRNPVTGAEEPHFPETSRFRRIITGNMVIIIMVAVVLIFLIAIILYRSILSIIIYKSHNAFFIFSAGRIASLTGSVLNLVVILLLSKVYTYLAQILTRWEMHRTQTKYEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYYKLFGIRNEDCGASGCLIELAQELLVIMVGKQVINNVQEFVLPKIKAWWNK-RKLHPTQRENGANITENVAPWETDYELLMCEGLFSEYLEMVLQFGFITIFVAACPLAPFFALVNNWVEIRLDSQKFVCEYRRPVAERAQDIGIWFTILQVITYLAVISNAFLIAFTSDFLPRLYYRYTTEGSLRGYMDFTLSVAPNNFTQSHMQCRYRGFRDDKGHHTPEYYNLLAIRLGFVIIFESSSGG 801

[Close]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 744.962 bits (1922), Expect = 0.000e+0
Identity = 404/791 (51.07%), Postives = 554/791 (70.04%), Query Frame = 2

Query:  302 DFILAWSEKEKE-----PHSKALY---RKKFESNLKKAGLELEEDFDETGKF--HYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWM-GLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYR--FSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-DSLDGYTNHSLSWSPKNSTV---IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            DF+L W E+ +      P S   +   RK F +NL K GL +EED  +  K   HY+K++ PW+++  +AE++ LR PLQ HP     +S + L  LH+PNIM+ D P +P ++Y C F++SK+ RFLGS++  T+FSSTQRH +V EIL T  YG+R+K E+G+ RM+ D I+ +A+PLHEG Y+ +   L  PE++  RQ+LY+YWAR+G W++YQPLDHIREYFGEKI FYFAW+ G YT WLLP +++G+ VF  G  T   + + KEIC   + + MCPLCD    C+ W L + C   K+ ++FD+PGTIFYSIF+++W+V+FLEYWKRK++SL +HW       EEERPR +YAAL  + ++NP+TG  EPYF ++ R PR +TG + + LM++VV+IF++ VI+Y+ L+ I +F+  N  L   A   AN T  +V LVLI+ +A++Y  IA  LT WEMHRTQS+ +N L  KVF+FQ VN+YSS  Y+ FFKG+F GYPGNY   FG RNE+C  GGCLIELA QL IIMVGKQI++N+QE+++P +Q W  R    +  G+++  +      L I+++D +L+   GL DEYLE+V+QFGFITIFV AFPLAP FAL+NNW+EIRLDA+K VC  +R V ER + IGVWF IL  +  I+ ISNAFL+AFTS+FLP+L YRY +  SLDGY + +L+++P++  V     CRY  +RD DG L  ++W+LLAVRL FVI+FEH V  + + +D LI DV  +L +KIKRE YLAKQAL +
Sbjct:    3 DFMLVWEEEMENEETVPPQSMDEHDSLRKIFLTNLSKIGLLIEEDIMQGEKINIHYLKLHAPWQVLQCYAEEINLRMPLQIHPMTKTHFSERLLKFLHLPNIMHADLPRQPQEYYNCFFRKSKLDRFLGSDHPETFFSSTQRHVIVKEILNTTPYGKRKKAEVGLDRMLRDHIFSAAFPLHEGSYDGTYLGLA-PEQMTRRQVLYKYWARWGCWFKYQPLDHIREYFGEKIAFYFAWLLGFYTCWLLPPALVGLVVFFVGWLTLHNDSTVKEICENGSHYQMCPLCDT---CKVWNLSNTCNMAKMGHIFDYPGTIFYSIFISLWSVSFLEYWKRKSSSLTYHWGC-TLVHEEERPRPEYAALAPLIRENPITGEKEPYFSEDDRTPRTVTGSIVLFLMISVVLIFLVTVILYQALLSISIFKTGNWFLATQATNIANMTGTLVFLVLIVIMARLYTTIADYLTRWEMHRTQSEHENALTVKVFIFQLVNYYSSPVYVGFFKGKFNGYPGNYGNLFGTRNENCPQGGCLIELAQQLFIIMVGKQILNNLQELILPIIQQWRQRRKLDEIRGKRLVQE------LNIWEDDYELLHNTGLFDEYLEMVMQFGFITIFVMAFPLAPLFALMNNWVEIRLDARKFVCRYRRSVVERVRGIGVWFDILSGLAHISIISNAFLIAFTSDFLPRLLYRYTYKSSLDGYVDFTLAYAPRDYVVANHTMCRYRDFRDQDGNLTLFYWKLLAVRLSFVIIFEHLVFLVARAIDWLIVDVAPDLKVKIKREEYLAKQALSE 782

[Close]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 402.905 bits (1034), Expect = 7.794e-133
Identity = 227/402 (56.47%), Postives = 299/402 (74.38%), Query Frame = 2

Query: 1442 GIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFY--RFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEI--VLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTV---IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            G + I+LM++VV+IF++ VI+YR ++ + M++  N +L   A   AN ++++VNL+LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y    G RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE + PK++ W    + +   G  V  +S        ++ED +LIP EGL +EYLE+  VLQFGFITIFVAAFPLAP FALLNNW+E+RLDAQK VCE +RPVAERA+DIGVWF IL+++  I+ I NAFL+AFTS FLPKL Y+Y +D +L GY N +LS++P +  V     CRY  YRD DG    ++W+LLA+RLGF+I FEH V  I +++D L+PDVP+ L IK+KRE YLAKQAL D
Sbjct:    1 GTMVIILMLSVVMIFLVTVIMYRGIVSVVMYKTGNAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRKLAALRGSHVAPESSR------WEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDDYVVNNYTHCRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 396

[Close]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 399.053 bits (1024), Expect = 3.460e-131
Identity = 213/366 (58.20%), Postives = 272/366 (74.32%), Query Frame = 2

Query: 1538 NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFY--RFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEI--VLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSP-KNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            N +L   A   AN ++++VNL+LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y    G RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE + PK++ W    + +   G  V  +S        ++ED +LIP EGL +EYLE+  VLQFGFITIFVAAFPLAP FALLNNW+E+RLDAQK VCE +RPVAERA+DIGVWF IL+++  I+ I NAFL+AFTS FLPKL Y+Y +D +L GY N +LS++P +N      RY  YRD DG    ++W+LLA+RLGF+I FEH V  I +++D L+PDVP+ L IK+KRE YLAKQAL D
Sbjct:   38 NAVLMTQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPKIKAWLQKRKLAALRGSHVAPESSR------WEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDENIAEANLRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 397

[Close]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000399.1 (pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 gene:ENSPMAG00000000358.1 transcript:ENSPMAT00000000399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 409.838 bits (1052), Expect = 2.474e-130
Identity = 274/705 (38.87%), Postives = 418/705 (59.29%), Query Frame = 2

Query:  359 RKKFESNLKKAGLELEEDFDETGKFH-YIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMK-ALNCLH--IPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKL---------TYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGV------IEPYFPKER-RLPRILTGIVCILLM--MTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFF-GLRNEDCQNGGCLIELAMQLAIIMVGKQII-SNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSN----SGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSW 2380
            R++FE NL  A LELE D ++  + H Y++I+ PW ++ R AE L ++ P +        + MK +   LH     I +   PN P   ++ E    K   F  S +K          ++F S  R ++V EIL+ ++   +   ++GI  ++ + +Y SA+PLH+G    S        ++N R++L++ WA Y ++Y+YQPL+ I++YFGEKIG YFAW+G+YT  L+P S++GI VFLYG    +++I   E C    +  MCP CD+   C+Y  L + C  ++ ++LFD+  T+ +SIFMA+WA TFLE+WKR    L + WD+   EE E++ R +Y A   + +K     +       E Y    R +LP  L    CIL M  ++  I+  +      + + +    +P L++N       TA ++NLV+I+ L ++Y  IA  LT  E+ +T+ +F+ +LIFK F+ +FVN Y+SI Y+AF KGR  GYP  Y Y     R E+C  GGCL ELA+QL IIM+GKQ++ +N+ EV +PK++    +  + L ++  H   S+     G+ +  +D +L P+ GL  EY+E+V+QFGF+T+FVA+FPLAPFFALLNN +EIRLD +K V E +RP A RAKDIG W+VIL  +  +A I NA ++A TS+F+P+L Y Y +    SL GY N++LS+
Sbjct:   91 REEFEQNLMDARLELEWDEEDQAEGHGYLRIHAPWLVLIREAEFLKIKMPTK------KVFEMKQSSGVLHGLGARINHALQPNVP---HSQEALSQKKLSFPFSRDKQKLFDIKSEDSFFDSATRSRIVFEILK-RVKCTKGPYKMGITSLIANGVYTSAFPLHDGELHGS--------EVNDRKLLHDEWASYNKFYKYQPLELIKKYFGEKIGLYFAWLGVYTQMLIPPSVVGIAVFLYGWLAAEKDIPGFETCVIGQNITMCPTCDKL--CKYKRLSENCDRVRSSHLFDNITTVLFSIFMALWATTFLEHWKRIETRLNYTWDLNGMEESEQQLRPEYEA--KLLEKKRKVDIKLAKTQTEEYGLSWRDQLPSFLINCSCILFMVLLSFAIVVGMIFYRITMNVLLANSTDPYLKSNRSAIIMATAFLINLVIILILDEIYGSIARWLTVIEVPKTEEEFETRLIFKSFMLKFVNSYTSIIYVAFLKGRITGYPKKYYYILPNYRMEECAPGGCLQELALQLCIIMLGKQLLQNNLFEVGIPKIK----KLCRYLHKKDHHKKASHLKEEDGMELGCKDYELEPFTGLNPEYMEMVIQFGFVTLFVASFPLAPFFALLNNVIEIRLDGKKFVTELRRPTAVRAKDIGTWYVILNGVAKLAVIINALVIALTSDFVPRLIYMYFYSPDGSLRGYVNYTLSY 769

[Close]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Match: ano11 (anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245])

HSP 1 Score: 390.578 bits (1002), Expect = 5.196e-128
Identity = 213/379 (56.20%), Postives = 272/379 (71.77%), Query Frame = 2

Query: 1544 LLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVP-------------KLQTWFY--RFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEI--VLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTV---IPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            L+   A   AN ++++VNL+LI+ + +VY  +A +LT+WEMHRTQ+ +++   FKVF+FQFVNFYSS FY+AFFKGRFVGYPG+Y    G RNEDC  GGCLIELA QL IIMVGKQ+I+NIQE + P             K++ W    + +   G  V  +S        ++ED +LIP EGL +EYLE+  VLQFGFITIFVAAFPLAP FALLNNW+E+RLDAQK VCE +RPVAERA+DIGVWF IL+++  I+ I NAFL+AFTS FLPKL Y+Y +D +L GY N +LS++P +  V     CRY  YRD DG    ++W+LLA+RLGF+I FEH V  I +++D L+PDVP+ L IK+KRE YLAKQAL D
Sbjct:   32 LMTQQAANIANISSSMVNLILILVMGQVYSSLAEQLTKWEMHRTQTQYEDAFTFKVFVFQFVNFYSSPFYVAFFKGRFVGYPGHYKKLLGTRNEDCGPGGCLIELAQQLIIIMVGKQVINNIQEFVFPLTLPPPAPRSCRRKIKAWLQKRKLAALRGSHVAPESSR------WEEDYELIPCEGLFEEYLEMGPVLQFGFITIFVAAFPLAPLFALLNNWVELRLDAQKFVCEYRRPVAERAQDIGVWFNILDALVNISVIINAFLIAFTSNFLPKLLYQYTYDRNLRGYINFTLSYAPDDYVVNNYTHCRYKDYRDQDGKHTLFYWKLLAIRLGFIIAFEHVVFFISRMIDWLVPDVPESLEIKMKRERYLAKQALAD 404

[Close]

BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49855 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0])

HSP 1 Score: 804.668 bits (2077), Expect = 0.000e+0
Identity = 413/781 (52.88%), Postives = 572/781 (73.24%), Query Frame = 2

Query:  302 DFILAWSEKEKEPHSKAL-YRKKFESNLKKAGLELEEDF--DETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDR--NISAKEICAGNN-SFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            DF+L + E EK+P  +++ YR+KF  NL K+ LE EE+   D+  K H+IKI+VPWE++  +AE+L+ RAPL+   N   +WS + L   H+PNI   + PN PPDF+TC F+ +K+++F+GS++  +YF+  +R +V  EILET  YG+R++GEIGI+R+V++ ++ + YPLH   Y     +   P  +   Q+L EYW R+G+W +YQPLDHIR+YFGEKIG YFAW+G YTAWL+  S +G+ VFLYGV T +   N  A E+C     +F MCPLCDE++GCQYW+L   C   KIAYLFD+  T+F+++F++ W+  FLEYWKRK  +LA+HWDVL+YEEE ERPR  +AAL    ++NPVTG++EP+FP E+R PR+ +GI  +  M+++V++F++ VI+Y++L+  P+ +NP  R  A+  AN T A VNL +IM L++VYE +AL LT WEMHRTQ+++++ L FKVF+FQF NFYSSIFY+AFFKG+ VGYPG+Y   FGLR E+C  GGCL+ELA QL IIMVGKQ+I+N+QE+ +P ++ W  R  +G  +    D         +++D +L+  EGL  EYLE++LQFGFITIFVAAFPLAPFFAL NN  EIR+D+ K VCE +RP+A+RA+DIG+WF IL+S+  IA ISNAFL+AFTS FLPKL YRY      SL+GYTN++L+W+P+N+T+ PCRY  +RD +G    ++W LLA+RLGFVI+FEH V  + +L+D+++PD+P EL I IKRE YLAKQAL D
Sbjct:    1 DFVLVYEEGEKDPPPQSIEYRQKFLENLAKSQLEFEEEITQDKKVKLHFIKIHVPWEVLLFYAEELSFRAPLEVGLNTKVNWSERMLEKFHMPNIFKEEVPNPPPDFFTCTFQANKLNKFIGSDDPDSYFTDVERTRVAYEILETAPYGKRQRGEIGIERLVEEGVFKAGYPLHVNCY--LNQQGYSPFLIYVSQVLKEYWGRWGKWLKYQPLDHIRDYFGEKIGIYFAWLGQYTAWLIMPSFLGLLVFLYGVATINSSDNKPALEVCDNPPWTFRMCPLCDEELGCQYWDLHISCKSGKIAYLFDNASTVFFAVFVSFWSCFFLEYWKRKEVTLAYHWDVLEYEEEAERPRPTFAALAPTVERNPVTGILEPHFPDEKRKPRLFSGIAIVFTMVSLVLVFMVGVIVYKLLVYRPLARNPSTRAYALQIANSTGAFVNLTIIMILSRVYERVALALTHWEMHRTQTEYEDSLTFKVFVFQFANFYSSIFYVAFFKGKLVGYPGHYRRLFGLRQEECSPGGCLMELAQQLVIIMVGKQMINNVQEIAIPLVKQWIKRKKRGTSK----DEIKPR----WEQDFELVENEGLFQEYLEMILQFGFITIFVAAFPLAPFFALANNIFEIRIDSDKFVCEVRRPIADRAQDIGIWFNILDSVAKIAVISNAFLIAFTSTFLPKLLYRYAVSENFSLEGYTNYTLAWAPRNTTLKPCRYQEFRDPEGHFTVFYWHLLALRLGFVIMFEHVVFFVMRLIDMMVPDIPTELEIIIKREAYLAKQALAD 771

[Close]

BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO49854 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8])

HSP 1 Score: 702.205 bits (1811), Expect = 0.000e+0
Identity = 375/700 (53.57%), Postives = 505/700 (72.14%), Query Frame = 2

Query:  551 LNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYF-----GEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFD--RNISAKEICAGNN-SFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            L   H+P     D PN PPD++T  FK +K+++FLGS+N  TYF+ T+R +V +EILET +YGRR+KGEIGI R+VD+  Y +AYPLH GP+   +       KLN RQ+L EYWAR+G WY+YQPLDHIR+ +     G KI  YFAW+G YTAWL+  S++G+ VF+Y   T +   N+ A E+C     ++ MCP C+  +GC  W+LK  C   K AYLFD+P T+ YSIF++ WAV FLE+WKRK  ++ H WDVL++E EEERPR  +AAL    ++NP+TG++EPYFP E+R PR+L+GI  I  M+++V++F++ VI+Y++L+  P+++NP L+  A  FA+GT A++NL++IM L++VYE +AL L  WEMHRTQ+++++ L  KVF+FQF NFYSSIFYIAFFKG+FVGYPGNY   FGLRNE+C  GGCLIELA QLA+IM+GKQ+I NIQEV +P+L+ +     +      Q+    +     ++ D +L+  EGL  EYLE+V+Q+GFIT+FVAAFPLAPFFAL NN  EIR+DA K V + +R  A+RA+DIGVWF IL+SIT +A ISNAFL+AFTSEFLPKL Y        SL+GY N+SL+W+P N+T  PCRY G+RD DG   ++FW LL +RL FVI+FEH V GI  L+D+ +PD+P+ L   IKRE Y+A QAL +
Sbjct:    2 LKKFHLPCPFKDDVPNTPPDYFTTTFKSNKLNKFLGSDNPDTYFTDTERARVASEILETAVYGRRQKGEIGISRLVDEGTYSAAYPLHVGPHGPDEM------KLNMRQVLKEYWARWGAWYKYQPLDHIRQAYEREGGGLKIAIYFAWLGQYTAWLIMPSVVGLIVFIYSFATINGPNNMPALEMCDHPAWTYPMCPNCE--VGCSVWDLKKSCSRAKHAYLFDNPMTVAYSIFVSFWAVLFLEFWKRKEVTIGHAWDVLEFESEEERPRPTFAALAPAVERNPITGLLEPYFPDEKRSPRVLSGIAIICGMVSLVMLFMVGVIVYKLLVIHPLYKNPNLQPYANQFASGTGAVLNLIIIMILSRVYEKLALLLNHWEMHRTQTEYEDNLTLKVFIFQFTNFYSSIFYIAFFKGKFVGYPGNYGTIFGLRNEECSPGGCLIELAQQLAVIMIGKQVIGNIQEVFIPELKKYLKNRKR------QNSKDEDEIKPRWEADYELLDNEGLFQEYLEMVIQYGFITLFVAAFPLAPFFALANNVFEIRIDADKFVNDLRRSTADRAQDIGVWFTILDSITKLAVISNAFLIAFTSEFLPKLLYAGVVSPNQSLEGYLNYSLAWAPPNTTSQPCRYRGFRDEDGNFTRFFWHLLTMRLVFVILFEHFVFGISTLIDVAVPDIPRALEDTIKREKYVATQALAE 687

[Close]

BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48050 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9])

HSP 1 Score: 503.056 bits (1294), Expect = 1.093e-165
Identity = 311/817 (38.07%), Postives = 473/817 (57.89%), Query Frame = 2

Query:  320 SEKEKEPHSKALYRKKFESNLKKAGLELE--EDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNK--------PPDFYTCEFKQ-------SKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEIC--AGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVT--GVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXP---MFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFV-GYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKL--IPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLS------------------------WSPKNSTVIPCRYPGYRDND---GILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYL 2596
            +E+++  +S A  R+ +E NLKKAGLELE  E  ++  K H++KI+ PW+++   AE++ +++P++        WS K L+   + +I   D P K        P   +   F++        K   F+G ++K T+FS+ +R ++   I   Q +G  R  +   + ++    Y +AYPLH GP E S+    +    N RQ L   WAR+GRW++YQP D I++YFG +IG YFAW+G Y A L+PA+I G+ VF+YG+         K+IC  A    FYMCPLCD++  C YW L   C +    + FD+  T+ ++IFM++WA  FLE+WKR+ A LA+ W ++ YE++EE+PR ++    +  +K+  +  G + P+ PK ++  R L G+V ++  M  +++  +  ++            + +P +R  A    + TAAI+NL+ I  L  VYE +A+ LTEWE  RT++DF +   +K++LFQFVN Y+SIFYIAFFK   V G PGNY  F G  R + C +GGCL++L +QL IIMVG+QII NI E+ +P L  W+         Q Q ++     +  ++ D KL  +P   L  EYLE+VLQFGF+T+FVAAFPLAP FAL+N   E+R+DA   VC+ +RP   RA+DIG W  I++ +  I+ + NAF++AFTS+F+P+L Y   +    +L GY N+SLS                        ++  N T   CRYPGY + +    + KQY W ++A RL FV  F++ V  + K +  L+PD P+ L ++IKR+ YL
Sbjct:   10 AEQKETENSHADKRRVYEENLKKAGLELEHEEGDNKKRKTHFVKIHTPWDVLAATAEEMMMKSPIRDSDIEIKSWSEKHLSEEFVTSIRSRD-PLKIHDSCITPPKKQFVAYFRKVINNPRLQKKQFFVGYHDKNTFFSAAERSRMTERICSQQRFGEERFDQGIKR-LIHQGTYTAAYPLHSGPEEVSR----KGHPSNERQKLRRDWARFGRWFKYQPYDAIKDYFGTEIGLYFAWLGFYAAMLVPAAIFGVAVFIYGIAQSTIFPPVKDICNKAYEAEFYMCPLCDKQ--CPYWSLVVNCPYAIWVHAFDNDSTVVFAIFMSIWATVFLEFWKRRQAVLAYEWHMMHYEDQEEQPRPEFIVTVTTLKKDKASQWGGMVPHVPKLQQY-RKLAGVVSLVAFMIALVLSAVVGVVIYRASVYGSLMAYPDPQVRKQAKMTTSITAAILNLICINLLKFVYEKLAMFLTEWENPRTETDFKDSFTYKMYLFQFVNNYASIFYIAFFKLNLVIGTPGNYRRFAGEYRLDGCSSGGCLMDLCIQLVIIMVGQQIIGNITEIAIPGLLKWWKM------RQAQKEAFEE--IPRWEVDYKLNTLPEHHLFWEYLEVVLQFGFVTMFVAAFPLAPLFALVNAVFELRVDAINFVCQFRRPTPRRAQDIGAWMSIMQGLANISVLVNAFVIAFTSDFIPRLVYTTAYSPDGTLRGYLNNSLSYFNVKDYDRMGAIGAREKPGDNYAYTVLNYTREYCRYPGYHEPEFPYEVSKQY-WHVIAARLAFVFAFQYIVYAVTKFVAWLVPDRPRHLELRIKRQEYL 808

[Close]

BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48048 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7])

HSP 1 Score: 486.108 bits (1250), Expect = 1.323e-158
Identity = 307/838 (36.63%), Postives = 465/838 (55.49%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWS----EKEKEPHSKALY------RKKFESNLKKAGLELEEDF-----DETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWEL-KDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPR--ILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANG-------TAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRF-VGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF------DSLDGYTNHSLS---------WSPKNSTVIP----------CRYPGYRDNDGILK--QYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQAL 2611
            +G +FN G  K+D++L +      ++K+P   A        R  FE+ L + GL +E +      ++  K H++K++VPW  +   AE+L L+APLQ +         K  +   I +      P KP  F    FK+ K+ +++G       F++  RH VV  I     +    KG    + +V +  Y + YPLH+G  +      E     N RQ L + W+   R ++YQPLD ++ Y+G  I  YFAW+G YTA L+P +I+G+ VF+YG+ +   + + ++ C  NN FYMCPLCD    C YW+L    CM+ ++ + FD+ GT+F +IF ++WA  FLE+WKR+ A LA+ W V ++EEEEE+ R ++AA     +KN +TG +EP+ P+     R   +  +V  ++++ +  +  + V    V   +    +  +R      A G       TAA++NL+ I  L   Y  +A+ LT WE  RT++D+++   +K++LFQFVN Y+SIFYIAFFK    VG PG Y    G  R E C   GC +EL +Q+ IIMVG+QII NI EV +P + TW            +     N  L  +++D  L P E   L  EYLEIVLQ+GF+T+F+AAFPLAP F+LLN+ +EIR+DA   V + +RP    A+DIG W+ ILE++T ++ + NAF+L+FTSEF+PKL Y+ ++       +L+GY N+SLS         W P  + + P          CRY GY DN    K  + +W ++A RL FV VF++TV  I   +   +PD P+ L ++ KRE +L K+ L
Sbjct:   13 TGRFFNKGGHKVDYVLVYETCQEREDKDPKFAAKMADFERKRDAFEAALSEQGLVIERESITSPQNDKVKRHFVKLHVPWRTLSSKAEELMLKAPLQENDIDLKTTGEKIFDPFRIKDS---SIPEKPKCF-MAYFKERKVDKYMGKAEPEKMFTALDRHYVVQRICYATRFAEGPKGVGLKQ-LVYEGAYCANYPLHDGDDDVIG---ESSYPSNDRQRLKKDWSSMKRIFKYQPLDTVKGYYGTAIALYFAWLGFYTAMLIPLAIVGLLVFIYGIGSSATSPTVRDACDTNNKFYMCPLCDRT--CSYWDLVSTTCMYARVTHFFDNDGTVFLAIFTSVWATLFLEFWKRRQAVLAYEWHVANFEEEEEQIRPEFAATAPTLKKNIITGKLEPHIPRRTLYQRYGAIGSVVAFMILLVIAAVIGVVVYRAAVFAALSGNSDSTIRARYAMIAIGSRIITSMTAALINLLCINILKLFYNRLAVWLTNWENPRTKTDYEDSFTYKMYLFQFVNTYASIFYIAFFKSEIVVGTPGRYKRIAGKYRLEGCSAQGCFLELCVQMLIIMVGQQIIGNITEVAIPAIMTWIK----------ERKEPKNKQLPQFEQDYNLQPQEEHNLFWEYLEIVLQYGFVTMFIAAFPLAPLFSLLNSIVEIRVDAINFVSQFRRPDTMIAEDIGAWYRILETLTRLSVLINAFVLSFTSEFIPKLVYKLKYAPEGSEGTLEGYLNNSLSAINVTVMEEWEPGTAPLNPTKNLNYTETFCRYKGYHDNTYPFKFNKQYWHVIAARLAFVFVFQYTVYAITSFIAWAVPDQPRSLELRSKREEHLTKKIL 830

[Close]

BLAST of Anoctamin vs. Ensembl Nematostella
Match: EDO48049 (Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU8])

HSP 1 Score: 466.848 bits (1200), Expect = 1.861e-152
Identity = 300/766 (39.16%), Postives = 438/766 (57.18%), Query Frame = 2

Query:  434 HYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDA--------PNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNS--FYMCPLCDEKIGCQYWEL-KDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLL--RNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFK-GRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKL--IPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF-------DSLDGYTNHSLS----------WSPKNS------TVIPCRYPGYRDNDGILK--QYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQ 2605
            H++K++VPW ++   AE++ L+  LQ +      W  K L    + ++  +D         P + P ++   F    + +F  +  +   FS+T RH V+  ++    +    KG    + + +   Y   YPLH+G  E  + E       N RQ L   WA +GR ++YQP D I+ YFG +IG YFAW+G YT  L+P +I G+ VF+YG+     +   +++C   N   + MCPLCD++  C YW+L K  C +  + + FD+  T+  ++  ++WA  FLE WKR+ ASLA+ W V D+EEEE   R ++AA     +KNPVTG+ EPY PK     R  T    I++M  +VI  ++ V+IYR  +   +  + +L  R  A T  + TAAI+NL+ I  L  VY  +A+KLT WE  RT++D+++   +K++LFQFVN Y+SIFYIAFFK G  +G PG Y    G  R + C   GC +EL +QL IIMVG+QII NI E+ +P L  W  R  +   +Q+            Y++D  L  +    +  EYLE+VLQ+GF+T+FVAAFPLAP F+LLN+ +EIR+DA   V + +RP A RA+DIG W  ILE +T ++ + NAF+L+FTS+F+P+L YR ++        SL+GY N+SL+            P+N       TV  CRYPGY  N    K  + +W ++A RL FV VF++TV    + L  LIPD  K L +KIKRE YLAKQ
Sbjct:    1 HFVKLHVPWLVLAHMAEEMNLKTALQENDIDCMTWMEKKLGRDRVESMRAMDPMAIKEPAIPEEKPSYFMATFTMKNLAKFHFAREQHKMFSTTDRHLVIQRLVYATRFAEGPKGLGLKQLLYEGA-YIGNYPLHDGDDEVKEGETIS----NDRQRLRRDWASFGRCFKYQPYDAIKSYFGTEIGLYFAWLGFYTGMLVPLAIAGLVVFIYGIVDATMSPPVRDVCDSKNEGRWIMCPLCDKQ--CSYWDLAKTTCAYAYVTHFFDNSLTVALAVVSSIWATLFLELWKRRQASLANKWHVSDFEEEET-IRPEFAATAPRLKKNPVTGLQEPYVPKRTLYQRYGTTGSIIVMMCLLVIAAVVGVVIYRAAVFASLSGSEILTIRMRARTVTSITAAIINLICINILKFVYSWLAVKLTNWENPRTRTDYEDSFTYKMYLFQFVNTYASIFYIAFFKSGLVIGTPGRYKRIAGKYRLDGCSEQGCFLELCIQLIIIMVGQQIIGNITEIAIPALMEWMKRRKEPKDKQLPQ----------YQQDFDLNSLGEHNMFWEYLEVVLQYGFVTMFVAAFPLAPLFSLLNSIVEIRVDAINFVRQFRRPDAARAEDIGAWSRILEGLTKLSVLVNAFVLSFTSDFVPRLLYRLKYAPDRDSGGSLEGYLNNSLAVFEVAYLEPGTEPENPLQSINYTVTTCRYPGYHSNTAPFKFNKQYWHVIAGRLAFVFVFQYTVYAFTQFLAWLIPDRTKTLDLKIKREQYLAKQ 748

[Close]

BLAST of Anoctamin vs. Ensembl Medaka
Match: si:dkey-83h2.5 (anoctamin 7 [Source:NCBI gene;Acc:101162585])

HSP 1 Score: 728.783 bits (1880), Expect = 0.000e+0
Identity = 389/796 (48.87%), Postives = 554/796 (69.60%), Query Frame = 2

Query:  278 FNDGKSKIDFILAWSEK--EKEPHSKA-----LYRKKFESNLKKAGL--ELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQ--NPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSP----KNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQD 2617
            F+D  +++DF+L W E     E  S A      +R++F   L+  GL  E  E      +  ++ +  PW+++C +AE+++LR PLQ       +WS K L+ L +PN +  D PN PPDFYTC+F+ +K+ RFLGS N+ T+F +TQRHQV+ EIL    YG  RKGE+GI R+V++ ++ +AYPLHEG ++     ++ P+ L  RQILY YWAR+  W +YQPLDHIREYFGEK+  YFAW+G+YT WLL ++++G  +FL G +    ++ AKE+C   N+F MCP+C+    C YW   ++C   K   LFD+ GT+F S+FM++WAVTFLEYWKR +++L+H WD  D+++  ERPR ++ A+  +  +NP+TG  EPYFP+++RL R LTG + I+LM++VV++F+IA+I+YR ++ I + +  N     +A   A+ + +++NL+LI+ L++VY  +A  LT WEMHRTQS +++  I KVF+FQFVNFYSS  YIAFFKGRFVGYPGNY   FG+RNEDC  GGCL+ELA ++ +IMVGKQ+I+N+QE + PK+ +W+ R    +  QV+        L  ++ D +L+  EGL  EYLE+VLQFGF+TIFVAA PLAP  AL+NNW+EIRLDAQK V E +RPV ERA+DIG+WF IL+ IT  A +SNAFL+AFTS F+P+LY+RY  D SL GYTN +L+ SP    +      CRY G+RD  G     ++ LLA+RLGF+I+FEH V  +G L+D+++PD+P+E+ +K+KRE Y+AK+AL +
Sbjct:   38 FSDKVTRVDFVLVWEEPHCSNEDSSAADPTHVQWREEFLRRLEGVGLLQEKTEVPQMKKRVCFVLLSAPWDVLCFYAEEISLRVPLQVVSTSDVNWSQKILSRLSLPNPLVQDVPNPPPDFYTCQFRTNKLQRFLGSENQETFFKTTQRHQVLYEILARTPYGSVRKGEVGIDRLVNEGVFTAAYPLHEGDFQLPTPPVD-PQSLGLRQILYAYWARWSCWRRYQPLDHIREYFGEKVALYFAWIGVYTGWLLLSALVGTVIFLMGFWIMAVDVPAKEVCDSGNTFIMCPICNI---CSYWNYSNICHTYKAGLLFDNAGTVFLSVFMSLWAVTFLEYWKRTSSALSHRWDCSDFQDIAERPRPEFTAMAPMTTRNPITGAEEPYFPEKKRLNRTLTGCMVIVLMVSVVLMFLIAIILYRTILSIIIHRSNNSFFSVSAGRIASLSGSVLNLLLILLLSRVYTSLAHLLTRWEMHRTQSKYEDMFILKVFVFQFVNFYSSPVYIAFFKGRFVGYPGNYKSLFGVRNEDCGAGGCLMELAQEMLVIMVGKQLINNVQEFISPKVMSWWQRMK--MSPQVKK---KGEELSPWEADYQLLVCEGLFGEYLEMVLQFGFVTIFVAACPLAPLCALINNWLEIRLDAQKFVTEYRRPVVERAQDIGIWFPILQFITHTAVLSNAFLIAFTSSFVPRLYFRYTKDSSLSGYTNFTLATSPHSFNQQHLNTSCRYRGFRDVKGDFLPEYFHLLAIRLGFIIIFEHVVFFVGSLIDMMVPDIPEEVEMKMKREHYMAKEALAE 824

[Close]

BLAST of Anoctamin vs. Ensembl Medaka
Match: ano3 (anoctamin 3 [Source:NCBI gene;Acc:101164148])

HSP 1 Score: 560.451 bits (1443), Expect = 0.000e+0
Identity = 343/834 (41.13%), Postives = 500/834 (59.95%), Query Frame = 2

Query:  254 PLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGK-FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMK-----ALNCLHIPN-----IMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPM--FQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGL-RNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRF------------DSLDGYTNHSLS----WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            P   SG +F DGK +ID+IL +  K+  P  +   R  FE NL+  GL LE++   T      +K++  W+ +C++AE++ +R P +     SD  S        L C  I N      M LD    P     D YT  F ++++H F  SN + T+FS++ R ++V+ +L+   Y   +      + ++ +  Y++A+P HEG Y+ S+  ++     N R +LYE WAR+G WY+YQPLD IR YFGEKIG YFAW+G YT  L+PA+++G+FVFLYG+FT D +  +KEIC  N +  MCP+C+E   C+ W L D C++ K+ +LFD+ GT+F++IFMA+WA  FLE+WKR+ A L + WD++D+EEEEE  R Q+ A  S  ++ NP++G  EP+ P   +L R++  +  I  M+++V+  + AV+++R++       F+   ++ N     +GT   +N ++IM L  VYE +A  LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G PG YS  F   R E+C   GCLI+L +Q+ +IM  KQI +N  E+  P LQ W+ R  + + +         + L  + +D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  ILE I  +A I+NAF++A TS+++P+  Y +++            + L GY N SLS    W   NS++   CRY  YR        Y     FW +LA RL F+IVFEH V GI   +  LIPD+PK+L  +++RE YL ++ + +A+L
Sbjct:  130 PSNSSGLFFRDGKKRIDYILVY--KKSSPQVEK--RCTFEKNLRAEGLMLEKEHSLTNNDIMLVKVHASWDTLCKYAERMNIRMPFRKKCYFSDKRSKGLGSRFHLRCQQIKNWFPKNPMKLDKEALPDLEESDCYTAPFSRARMHHFTISNRE-TFFSNSTRSRIVHHVLQRTKYEDGKSKMGINR-LLGNNTYEAAFPPHEGGYK-SRHPIKTHGPQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGVFVFLYGLFTMDSSQVSKEICEANTTI-MCPMCEET--CEPWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPFSDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFASFRWHFVKKNLQFATSGTGVCLNFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGKYSKLFNRWRLEECHPSGCLIDLCLQMGVIMFFKQIWNNFMELGYPLLQNWWSR--RKIKKGGGGGQNVETQLPQWDKDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPCMDKGQHHENECLQGYVNSSLSVFDMWEVNNSSMSRYCRYRDYRAPPWSSVPYKFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRREKYLMQEMMYEAEL 951

[Close]

BLAST of Anoctamin vs. Ensembl Medaka
Match: ano3 (anoctamin 3 [Source:NCBI gene;Acc:101164148])

HSP 1 Score: 528.865 bits (1361), Expect = 7.821e-174
Identity = 333/825 (40.36%), Postives = 484/825 (58.67%), Query Frame = 2

Query:  254 PLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGK-FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPN-----IMYLDAPNKP----PDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQK-NPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPM--FQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG-LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPY--EGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD--------SLDGYTNHSLS----WSPKNSTVIP-CRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            P   SG +F DGK +ID+IL +  K+  P  +   R  FE NL+  GL LE++   T      +K++  W+ +C++AE++ +R P +     SD  S     C  I N      M LD    P     D YT  F ++++H F  SN + T+FS++ R ++V+ +L+   Y   +      + ++ +  Y++A+P HEG Y+ S+  ++     N R +LYE WAR+G WY+YQPLD IR YFGEKIG YFAW+G YT  L+PA+++G+FVFLYG+FT D +  +KEIC  N +  MCP+C+E   C+ W L D C++ K+         IF +      A  FLE+WKR+ A L + WD++D+EEEEE  R Q+ A  S  ++ NP++G  EP+ P   +L R++  +  I  M+++V+  + AV+++R++       F+   ++ N     +GT   +N ++IM L  VYE +A  LT  E  RT+S+++N    K+FLFQFVN  SS FYIAFF GRF G PG YS  F   R E+C   GCLI+L +Q+ +IM  KQI +N  E+  P LQ W+ R  + + +         + L  + +D  L P    GL+DEYLE+VLQFGF TIFVAAFPLAP  ALLNN +EIRLDA K V + +RP+  RA DIG+W  ILE I  +A I+NAF++A TS+++P+  Y +++          L GY N SLS    W   NS++   CRY  YR        Y     FW +LA RL F+IVFEH V GI   +  LIPD+PK+L  +++RE YL ++ + +A+L
Sbjct:   86 PSNSSGLFFRDGKKRIDYILVY--KKSSPQVEK--RCTFEKNLRAEGLMLEKEHSLTNNDIMLVKVHASWDTLCKYAERMNIRMPFRKKCYFSDKRSKGLGRCQQIKNWFPKNPMKLDKEALPDLEESDCYTAPFSRARMHHFTISNRE-TFFSNSTRSRIVHHVLQRTKYEDGKSKMGINR-LLGNNTYEAAFPPHEGGYK-SRHPIKTHGPQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGVFVFLYGLFTMDSSQVSKEICEANTTI-MCPMCEET--CEPWTLSDSCVYAKVREQLHGECLIFSA------ATVFLEFWKRRRAELTYDWDLIDWEEEEEELRPQFEAKYSRKERVNPISGKPEPFQPFSDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFASFRWHFVKKNLQFATSGTGVCLNFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGKYSKLFNRWRLEECHPSGCLIDLCLQMGVIMFFKQIWNNFMELGYPLLQNWWSR--RKIKKGGGGGQNVETQLPQWDKDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGILEGIGVLAVITNAFVIAITSDYIPRFVYAFKYGPCFSGPSRCLQGYVNSSLSVFDMWEVNNSSMSRYCRYRDYRAPPWSSVPYKFTLQFWHVLAARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRREKYLMQEMMYEAEL 892

[Close]

BLAST of Anoctamin vs. Ensembl Medaka
Match: ENSORLT00000011801.2 (anoctamin-1 [Source:NCBI gene;Acc:101173596])

HSP 1 Score: 529.25 bits (1362), Expect = 4.974e-173
Identity = 326/823 (39.61%), Postives = 492/823 (59.78%), Query Frame = 2

Query:  305 FILAWSEKEKEP-----HSKALYRKKFESNLKKAGLELEEDFD-ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAH----------PNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALC-----SIFQKNPVTGVIEPYFPK---ERRLPRILTGIVCILLM--MTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFF-GLRNEDCQNGGCLIELAMQLAIIMVGKQII-SNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNK----------LIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD---SLDGYTNHSLSW----------SPKNST---VIPCRYPGYRD----NDGI-LKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYL 2596
            F+   S K  EP         L R++FE+NL +AGLE+E + + +     + +I+ PW ++CR AE L +R P +A            + S  W  + LN    P +   D  +    F +  F + K+H +   ++K T+F +  R ++V EIL   +   R    IGI  ++   +YDSA+PLH+G Y+     +   E+ N RQ+L+E WARY  +Y++QP+D +R+YFGEK+G YFAW+G+YT  L+PASI+GI VF YGV T D N+ + E+C    +F MCPLCD    C +W L   C   + ++LFD+P T+F++IFM++WAV FLE+WKR+  SL+  WD+   EE+EE PR +Y  +         +        EP   K   + RLP     I  IL M  +T   +F + +    V   + M  +P  ++N       TA I+NLV+I+ L ++Y  +A  LTE E+ +T+++F+ +LI K F+ +F+N Y+ IFY+AFFKGRFVG PGNY Y F   R E+C  GGCLIEL +QL+IIM+GKQ+I +NI E+ +PKL+    +  + L E+   ++  N+     +ED K          L P++GL  EY+E+++QFGF+++FVA+FPLAP FALLNN +EIRLDA+K V E +RPVA RAKDIG+W+ IL  +  ++ I NAF+++FTS+F+P+L Y+Y +    ++ G+ +H+LS+          +P+NS    V  CRY  YR+    +D   L + +W +LA RL FVI+F++ V  +G ++  +IPDVPK +  ++KRE  L
Sbjct:   98 FMELGSAKGSEPMEAIDQEMHLIRQEFEANLLEAGLEIEREKEVKPNGPSFTRIHAPWPVLCREAEFLKIRVPTKASYELKEERGFGSSMSSIW--RKLNQPFQPKVSLQD--HGSTKFLSHCFSRDKLHLY-NISSKDTFFDNATRGRIVYEILRRTV-CVRTCQTIGISTLIAKGVYDSAFPLHDGDYKV----IGHLEERNDRQVLHEEWARYSAFYKFQPIDLVRKYFGEKVGLYFAWLGVYTQLLVPASIVGIIVFGYGVATVDTNLPSLEMCDERFNFTMCPLCDG--ACDFWHLSTACGTARASHLFDNPATVFFAIFMSLWAVLFLEHWKRRQISLSFSWDLTGIEEDEEHPRPKYETILLQKRQRKQKTKKKRKKSEPAVDKLTWKDRLPGYFINISSILFMFGLTFSAVFGVIIYRITVSALMAMSPDPETKSNVRVTVTATAVIINLVVILVLDEIYGAVAQWLTELEIPKTETNFEERLIMKAFMLKFMNAYAPIFYVAFFKGRFVGRPGNYVYVFDNYRMEECAPGGCLIELCIQLSIIMLGKQLIQNNIFEIGIPKLK----KLIRSLKEK---EATPNA-----REDEKPPQQWNLDYALAPFDGLTPEYMEMIIQFGFVSLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAARAKDIGIWYNILSGMGKLSVIINAFVISFTSDFIPRLVYQYMYSPSGTMHGFIDHTLSYFNVTNFKPGSAPQNSAHEDVTFCRYKDYREPPWSSDAYQLSKQYWSVLAARLAFVILFQNLVMFLGLIVAWVIPDVPKTIVEQLKREKKL 896

[Close]

BLAST of Anoctamin vs. Ensembl Medaka
Match: ano5a (anoctamin 5 [Source:NCBI gene;Acc:101164640])

HSP 1 Score: 518.85 bits (1335), Expect = 4.665e-170
Identity = 328/858 (38.23%), Postives = 501/858 (58.39%), Query Frame = 2

Query:  221 EEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE-EDFDETG--KFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXX---XXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAG--NNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERP--RAQYAALCSIFQKNPVTGVIEPYFPKERRLPRI-LTGIVCIL---LMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVT-------FANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFG----LRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWF-YRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-----SLDGYTNHSLSW----------SPK--------NSTVIPCRYPGYRDNDGILKQY-----FWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            E GI+++      +    +F DG  +IDF+L++ + +K+   K   R+ FE+NL K GLELE ED  E+   K +++KI+ PWE++  +A+ L ++ P +A+  P  D S   +N L  P  +        PDF+T  F +SK   FL  +    +  ST R+++V  IL    Y R     + + GIKR++++  Y +A+PLH+  Y     ++      + R  LY+YWA +  +++ QPL+ IR+Y+GEKIG YFAW+G YT  L  A+++G   F+YGV T+D N  +KEIC+     +  MCPLCD+K  C +W+L   C     ++LFD+ GT+F++IFM +W   FLE+WKR+ A L + WD++D+EEE+++   R +Y   C+  + N +T  +EPY P   +  RI L+G   +L   L++  +I  I   +         M  +P      V          + TA+ +N V+IM L  +YE +A+ +T+ E+ +T  +++N+L  K+FLFQFVN+YSS FY+AFFKG+FVGYPG+Y+Y FG    LRNE+C  GGCLIEL  QL I+M GKQ+  NIQE LVP L  W+  R ++   E +            +++D+ L  +   GL  EYLE+V+QFGFIT+FVA+FPLAP  AL NN +EIR+DA KL  + +RPVA +A  IG W  IL  +  ++ ++NAF++AFTS+ +P+L Y Y +      ++ GY N+SLS            P+        NS++  CRY  YR+  G   QY     FW +LA +L F+I+ EH V  +   +  +IPDVP ++  ++KRE YL ++ L + ++
Sbjct:   44 ESGIQKQQQ----SKDSVFFRDGVRRIDFVLSYVD-DKDGERKQERRRVFEANLVKVGLELEIEDKSESDDRKTYFVKIHAPWEVLATYADVLKIKVPFKANDIP--DNSEMPMNWLSTPFRLPEPIMQPEPDFFTAPFDKSKSDFFLIEDRDKFFLPST-RNRIVYYILSRCSYIRDECGERDKKGIKRLLNNSTYTAAFPLHDSRYWTKSKDVNCD---SDRYNLYKYWAGFFSFFKEQPLNLIRKYYGEKIGLYFAWLGFYTEMLFFAAVVGTLCFVYGVLTYDDNEWSKEICSDEIGGNIVMCPLCDKK--CGFWKLNTTCNSSWQSHLFDNVGTVFFAIFMGIWVTLFLEFWKRRQARLEYEWDLVDFEEEQQQLQLRPEYETKCNSRKLNRITQEMEPYLPITSKCARICLSGATVLLWISLIIACIIGVIAYRLAVYAAFASIMKDSPTSNLEVVGPYITPQLATSVTASCINFVIIMILNLMYERVAVWITDMEIPKTHLEYENKLTVKMFLFQFVNYYSSCFYVAFFKGKFVGYPGDYAYMFGKWSKLRNEECDPGGCLIELTTQLVIVMTGKQVWGNIQEALVPWLMNWWASRKARSYPESLYSR---------WEQDHDLQGFGQLGLFYEYLEMVIQFGFITLFVASFPLAPLLALFNNIIEIRVDAWKLTTQFRRPVAAKAHCIGAWEEILNGMAVLSVVTNAFIVAFTSDMIPRLVYMYAYQPEGEMNMKGYINNSLSVFNISEIPLPNRPEDGENPLWFNSSITTCRYRDYRNPPGHENQYSHTMQFWHILAAKLAFIIIMEHVVFLVKYFVAWMIPDVPSDVKARVKRERYLVQEYLHNYEV 879

[Close]

BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000006381.1 (SMESG000006381.1)

HSP 1 Score: 1625.14 bits (4207), Expect = 0.000e+0
Identity = 831/833 (99.76%), Postives = 833/833 (100.00%), Query Frame = 2

Query:  161 MIRESFRKLIGKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 2659
            MIRESFRKLIGKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYGRRRKGEIGIKRMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDV+DYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTVVIIFIIAVIIYRVLIEIPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEV+VPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVAAFPLAPFFALLNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE
Sbjct:    1 MIRESFRKLIGKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYGRRRKGEIGIKRMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVMDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTVVIIFIIAVIIYRVLIEIPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVIVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVAAFPLAPFFALLNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADLITWETFENEKE 833

[Close]

BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000052528.1 (SMESG000052528.1)

HSP 1 Score: 911.753 bits (2355), Expect = 0.000e+0
Identity = 478/791 (60.43%), Postives = 613/791 (77.50%), Query Frame = 2

Query:  275 YFNDGKSKIDFILAWSEKEKEPHSKAL-------YRKKFESNLKKAGLELEEDFDETGKF--HYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYE-CSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLI-IYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS-LDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQAL 2611
            YF+DG  KID+I+AW E++   +  ++       YRK+FE NLKK  +E+E+D +E+ K   H +KI++PW+++C +AE++ LRAPLQ      ++ + K L  L+IPNIM L+ P +P  ++TC FK+S + R++G  N+ T+F++TQR QV  EIL TQ+YG+RRK EIGI R++++ IY +AYPLH+GP++ C K      + LN RQ+LYE WA++  WY+YQPLDHIREY+GEKIG YFAW+G+YT WLLPASIIGI VF+YG+ T ++N+ + EIC  N ++ MCPLC+E IGC YW L DVC + KI Y+FDHPGT+F+SIFMA WAV+FLE WKRKNASLA+HWDV+ +EEEE+RPR +YAALC   + NPVTG++EP+FP  R+  R LTGI  I +M  +++IFIIAVIIYRVLI IP+FQNPLLR+ A+ FAN +AA VNL+LIMCL +VYE +A KLT+WEMHRTQ++FD+ LI KV+LFQFVNFYSSIFYIAFFKGRF GYPGNYS FFGLRNE+C NG CL ELA QLAIIMVGKQII+N QE+ VPK+ TWFY+ SKGL +    D   N  LI  + ED KL+PYEGL +EYLE+VLQFGFITIFVAAFPLAP FALLNNW+EIRLDA+KLVCET+RP++ERA+DIG W VIL++I  ++ ISNAFL+AFTSEFLPKL Y+YR+D  L GY N +LSW+P  S   PCRY   RD  G     +W+LLA+R GFVI+FEH V  +  L+D++IPD+   L ++++RE YLAKQAL
Sbjct:   74 YFSDGIRKIDYIIAWEEEKNGSNVNSIENVKHQNYRKRFEENLKKISVEMEQDDEESDKIIIHCVKIHIPWDLLCHYAEEMNLRAPLQMRNEGRENNTEKLLKLLYIPNIMQLNIPRRPMAYFTCNFKKSNLDRYIGCKNQETFFTATQRQQVAYEILATQVYGKRRKAEIGIDRLLEEGIYSAAYPLHDGPFQQCGKN----ADSLNERQMLYENWAKWSMWYKYQPLDHIREYYGEKIGLYFAWLGMYTVWLLPASIIGILVFIYGLLTINKNVPSNEICQSNQTYRMCPLCNEDIGCPYWYLSDVCFYSKITYMFDHPGTVFFSIFMAFWAVSFLENWKRKNASLAYHWDVIHFEEEEQRPRPEYAALCPSVKMNPVTGLMEPHFPTMRKAFRFLTGICVISIMFVLILIFIIAVIIYRVLIAIPLFQNPLLRSKAIIFANTSAAFVNLILIMCLGRVYEKLAYKLTQWEMHRTQTEFDDHLILKVYLFQFVNFYSSIFYIAFFKGRFNGYPGNYSLFFGLRNEECSNGSCLFELAQQLAIIMVGKQIINNFQEIFVPKILTWFYQCSKGLDKVSNLD--ENKELIKFWAEDYKLLPYEGLFEEYLEMVLQFGFITIFVAAFPLAPLFALLNNWVEIRLDAKKLVCETRRPISERAQDIGKWSVILDAIVHLSVISNAFLIAFTSEFLPKLIYKYRYDDQLRGYVNFTLSWAPNGSLTEPCRYRALRDEYGSYTIIYWQLLALRFGFVIIFEHVVFSVAHLIDIVIPDISYNLQVRMRRENYLAKQAL 858

[Close]

BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000053932.1 (SMESG000053932.1)

HSP 1 Score: 862.448 bits (2227), Expect = 0.000e+0
Identity = 455/790 (57.59%), Postives = 594/790 (75.19%), Query Frame = 2

Query:  272 YYFNDGKSKIDFILAWSEKE----KEPHSK---ALYRKKFESNLKKAGLELEEDFDETGKF--HYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXXXMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFD-SLDGYTNHSLSWSPKNSTVIPCRYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQAL 2611
            YY NDG  +ID+++ W +       +P  +     YRK+F+  L K GL  EE+ +E+ K   ++IKI++P+ IMC +AE L  R PLQ  P  +  +S + L    IPN M  + P  P  F T  FK  ++ ++LG  N+ T+FS+TQRHQV  EIL T +YGR+ KGEIGI RM+D+EIY +AYPLHEGP E     L + +  N RQIL+EYWA++ ++Y+YQP+++IREY+GEKI  YFAW+GLYTAWL PAS++GIFVF+YG+ T      +KEIC  NN+F MCPLC+ + GC+YW L D+C + ++ YLFDHPGT+F+SIFM++WAV FLE WKRKNA L++ WD +DYEEE+E+PR +Y AL +  + NPVTG+ EPYFP   R+ R+LTG++CI++M  +VIIFII VIIYR+LI IP+F NPLLR+ A+ FA+ +AAIVNL+LIM L  VYE +A KLT+WEMHRT+++F++ L  KV+LF+FVNFYSSIFYIAFFKGRF GYPG YS FFGLRNEDC NG CL ELA Q+AIIMVG QII+NIQE+ +PKL TWF+RF KGL   VQ  S  +    ++ ED KL+PYEGL DEYLE+++QFGFITIFVAAFPLAPFFAL+NNW+EIRLDA KLV  T+RPVAERA+D+G WF+IL  I  ++ ISNAFL+AFTS+F+PK  Y+Y  +  LDGY N +L+W+P NS   PCRY  +RD +G L +++W LLA+RL FVIVFEH V G+  L+D+LIPDVP+ L I+++R+ Y+AKQAL
Sbjct:   35 YYLNDGIRRIDYVIVWEQDRIAINVDPERRRRITEYRKRFQEKLLKMGLSCEEEIEESEKMMINFIKIHIPFNIMCIYAEALNFRVPLQIGPPHTPHFSERVLKFFLIPNFMKNELPYSPDCFATAAFKTDQLEKYLGYTNEDTFFSTTQRHQVAREILATTVYGRQTKGEIGIDRMIDEEIYSAAYPLHEGPAEVPTDLLGKVDLWNRRQILFEYWAKWSKFYKYQPIENIREYYGEKIAIYFAWLGLYTAWLFPASLVGIFVFVYGILTMKSYTISKEICDTNNTFKMCPLCNYEKGCRYWNLSDICFYSQMTYLFDHPGTVFFSIFMSVWAVAFLENWKRKNAELSYRWDTVDYEEEDEKPRPEYVALATEKRVNPVTGIEEPYFPVNLRMKRMLTGVMCIVVMFMIVIIFIIGVIIYRILIAIPLFDNPLLRSKALIFASVSAAIVNLILIMSLGLVYEKLAYKLTQWEMHRTETEFEDHLTVKVYLFEFVNFYSSIFYIAFFKGRFNGYPGKYSLFFGLRNEDCSNGSCLFELAQQMAIIMVGNQIINNIQEIFLPKLVTWFHRFKKGLNNMVQL-SGKDVEPKLWSEDYKLLPYEGLFDEYLEMIVQFGFITIFVAAFPLAPFFALINNWLEIRLDASKLVLSTRRPVAERAQDMGTWFIILNLIVKLSIISNAFLIAFTSDFIPKQVYKYSHNFLLDGYVNFTLAWAPNNSLSEPCRYRDFRDVNGKLTRFYWRLLAIRLTFVIVFEHIVFGVAYLIDILIPDVPESLQIEMRRKNYMAKQAL 823

[Close]

BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033728.1 (SMESG000033728.1)

HSP 1 Score: 346.665 bits (888), Expect = 1.180e-104
Identity = 226/603 (37.48%), Postives = 332/603 (55.06%), Query Frame = 2

Query:  773 MVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCSIF---QKNPVTGVIEPYFPK-ERRLPRILTGIVCILL--MMTXXXXXXXXXXXXXXXXXXPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSKGLGEQV---QHDS---------------------CSNS-----GLIIYKEDNKLIP--YEGLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYYRYRFDS---LDGYTNHSLSW---SPKNSTVIPCRYPGYRDNDGILKQ 2452
            ++ + ++DSAY LHE P      +LE  E  N R +LY++W      ++ QPLDHI+ YFGEK+ FYFAW+G YT WLLP S++GI V LY +     +I  KEI  G N   MCPL     GC++W+L D      +  L D+  T+  ++ M++WA  FLE WKR+   LA+HW+V D E E+E  R ++ AL       + N ++G  EP+ P   RR+P +      +LL   M +  +  I +        + M  +  + N +      T ++++LV+IM L  VY  +A+ LT+ E HRTQS +D+ +  K++L +F+N YSSIFYI F +      P   S    ++   C  GGCL++L++QLA IM+GKQIIS+I+E  +P+L +   R+     E+    Q D+                     C ++      LI    DN L       L  EYLE+++QFGFITIF+ AFPLAP  AL NN  EIR DA K     +RPVA+R KDIG+W  I+  + TIA  SNA L+AF + ++ KL Y   +     L+G+T+ SLS+   S  N+T+    Y G++   G++K+
Sbjct:  277 LISEGVFDSAYILHERPLN-EDDDLENVEN-NERNLLYKHWVSMRNIFRLQPLDHIKLYFGEKVAFYFAWLGYYTYWLLPISLLGIIVSLYNIVYTSNDIVVKEIYQGTN-ITMCPLMCSSRGCRFWKLSDAYSRFFLIRLLDNGATVLMAVVMSIWASLFLEMWKRQQVQLAYHWNVHDMEYEDEPARPEFVALIDKNYPKKTNLISGKEEPFIPFWRRRMPVMFFTYSTVLLSIAMALAFLGGIILYKLVSFSLMRMHHSRTISNMSSIITAATGSLLSLVIIMSLTLVYSRVAVWLTDMEHHRTQSQYDSSVTLKLYLLEFINNYSSIFYIGFIQPFTQPIPSFRSSSM-IKPRGCPAGGCLLDLSLQLAFIMIGKQIISHIKEYALPRLVSTVKRYKLKQAEEKLINQSDAEMEADRVEVAIKDKATILDPKCIDTWKVEPELIRCYADNILSDPGPRPLFGEYLEMLIQFGFITIFIPAFPLAPLLALTNNLFEIRSDALKFARALRRPVAQRVKDIGIWVSIMSMVATIAVKSNAILIAFATTYIDKLIYIIGYSENGFLNGFTDFSLSYMNSSEFNATL----YGGHKLTWGLMKR 871

HSP 2 Score: 58.5362 bits (140), Expect = 2.045e-8
Identity = 48/184 (26.09%), Postives = 81/184 (44.02%), Query Frame = 2

Query:  266 SGYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE----------------EDFDETGK------FHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWSMKAL-----NCLHIPNIMYLDAPNKPPDFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLY 736
            +G +F DG  KIDF+L + E+  +  +  + R  F  +L K GLE+E                 D D  G         +IK++  WE +CR+AE L +R  + +      D++ K +           NI  ++     P  +T  + +SK + F    +  T+F++ +R  +VN IL    Y
Sbjct:   23 NGMFFVDGVRKIDFVLVY-ERINDNRTNQIKRMTFLKSLLKEGLEIEIQDDGCKVYPFKENSYYDNDSVGSPSHRSNIVFIKVFATWETLCRYAEVLKIRKQMLSL-GFEYDFNRKTIFQRLFETFDFLNIFNINELKPIPRGFTTPYSKSKEYLFDIPEDNATFFTAAERSLIVNYILRRASY 204

[Close]

BLAST of Anoctamin vs. Planmine SMEST
Match: SMESG000033732.1 (SMESG000033732.1)

HSP 1 Score: 333.954 bits (855), Expect = 1.499e-99
Identity = 281/909 (30.91%), Postives = 445/909 (48.95%), Query Frame = 2

Query:  269 GYYFNDGKSKIDFILAWSEKEKEPHSKALYRKKFESNLKKAGLELE----------------EDFD----ETGKFHYIKIYVPWEIMCRFAEKLALRAPLQAHPNPSDDWS------MKALNCLHIPNIMYLDAPNKPP--DFYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYXXXXXXXXXXX---------------------------------------XMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGRWYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTFDRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPGTIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALCS---IFQKNPVTGVIEPYFPK-ERRLPRILTGIVCILLMMTXXXXXXXXXXXXXXXXXXPMFQNPL-LRNNAVTFANGTAAI---VNLVLIMCLAKVYEIIALKLTEWEMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFFGLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWF--YRFSKGLGEQVQHDS---------------CSN-----------SGLIIYKEDNKLIPYE--GLLDEYLEIVLQFGFITIFVXXXXXXXXXXXXNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESITTIACISNAFLLAFTSEFLPKLYY---RYRFDSLDGYTNHSLSW--------SPKNSTVIPCRYPGYR------DNDGI-LKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPKELYIKIKRETYLAKQALQDADL 2626
            G +F D   +IDF+L + ++  +   K   R  F  +L   GLE+E                E+ D    E+    ++KI+  W+ +CR+AE + +R  +    N   D++       +         I  +D     P    YT  F + K + F    N+  +F+  +R  +VN IL+ + Y    K    +                                        +++ ++++++A+ LHE      K    + +K N R +LY++WA     +++QPLDHIR YFGE + FYFAW+G YT WL P ++ G+ V +Y + T  R+I  +EI   NN   MCP+   +  C+ W+L    +   +  L D+  T+  +  +++W   FLE W+RK  +LA  W+V D E E+E  R +YAAL     I Q N ++G  EP+    +  LP  +  I  IL  + + +  +  + + +      + +N L L+   V     TAAI   ++L+ I+ L  VY  +A+ LT+ E HRTQS +DN +  K+++ +F+N YSS+FYI F        PG+ S F  ++ + C  G CL++L+MQL  I+VGKQIISNI    +P+L +    YR  +   + ++  S               CS+           S L I  +DN L   E   L  EYLE+++QFGFITIF+  FPLAP  A++NN MEIR DA+K V   +RPVA+R KDIG+W  IL +I  I   SNA L+AF + ++ ++ Y     R   L G+ + SLS+        S   S    C Y G+R       N+ +     FW++LA ++ FV +FE  V+   K+  ++IP++P E  I +KRE  +  + +   +L
Sbjct:   26 GMFFTDRVRRIDFVLVY-QQLLDSEEKRNKRISFIESLIDEGLEIEIQNIGGRIINIADSVNENSDDITCESKNLVFVKIHASWDTLCRYAEIMKIRKSIM---NAGVDYNYIFQSFFEKFVDFDFFRIFSIDNKRLKPIAQGYTYPFSKQKYYLFDIPVNRSEFFTPVERSLIVNYILKRKGYKSNHKPISNLSNEKMLVELEPIHSDKRSNSNDSITNEVEENGSNLNFGIAKLISEKVFETAFILHE------KFSNGKYKKENMRVLLYKHWATLTNIFRHQPLDHIRLYFGEMVAFYFAWLGFYTFWLFPIALFGVCVTIYNLATIPRDIIIQEISERNN-ITMCPVFCIEGSCESWKLSAGYVQFYLIRLIDNGATVILAGVVSVWVFLFLEMWERKQFTLAFRWNVHDLEVEDEPLRPEYAALLEKNYISQFNKISGKEEPFISFWKNTLPIQMLTISTILFSIVLTLACLTGITVTKT-----IIRNLLRLQLTYVMSKLSTAAIGSLISLITIIILTSVYSRVAVWLTDLEHHRTQSQYDNSVTGKLYILEFINNYSSMFYIGFAHPYTKVKPGSDS-FSMIKPQGCLTGDCLLDLSMQLIFILVGKQIISNIINFSIPRLCSSIKEYRIKRADSKFIKRRSVHRPTITDYEISEVECSDIYTDCNGVKLQSELKICYQDNILSDPEPRPLFKEYLEMIIQFGFITIFILPFPLAPLLAIINNLMEIRSDAKKFVTVYRRPVAQRVKDIGIWMDILTTIAKIVVKSNALLIAFATSYIDRMIYIIVHSRNFDLGGFVDFSLSFMNTTEFNISSSISNETHCSYIGFRYPPWDVHNEPMSYTPVFWQMLAAKIAFVYLFETFVSLFVKIFLMIIPNIPDEYRIAMKREAAITNEFILKIEL 917

The following BLAST results are available for this feature:

BLAST of Anoctamin vs. Ensembl Human
BLAST of Anoctamin vs. Ensembl Celegans
BLAST of Anoctamin vs. Ensembl Fly
BLAST of Anoctamin vs. Ensembl Zebrafish
BLAST of Anoctamin vs. Ensembl Xenopus
BLAST of Anoctamin vs. Ensembl Mouse
BLAST of Anoctamin vs. UniProt/SwissProt
BLAST of Anoctamin vs. TrEMBL
BLAST of Anoctamin vs. Ensembl Cavefish
BLAST of Anoctamin vs. Ensembl Sea Lamprey
BLAST of Anoctamin vs. Ensembl Yeast
BLAST of Anoctamin vs. Ensembl Nematostella
BLAST of Anoctamin vs. Ensembl Medaka
BLAST of Anoctamin vs. Planmine SMEST

BLAST of Anoctamin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANO7	0.000e+0	48.38	anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677]	[more]
ANO7	0.000e+0	47.58	anoctamin 7 [Source:HGNC Symbol;Acc:HGNC:31677]	[more]
ANO1	0.000e+0	40.81	anoctamin 1 [Source:HGNC Symbol;Acc:HGNC:21625]	[more]
ANO3	6.582e-179	41.61	anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004]	[more]
ANO3	5.184e-178	41.61	anoctamin 3 [Source:HGNC Symbol;Acc:HGNC:14004]	[more]

BLAST of Anoctamin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4


Match Name	E-value	Identity	Description
anoh-1	2.165e-57	25.85	Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286]	[more]
anoh-1	3.236e-57	25.85	Anoctamin [Source:UniProtKB/TrEMBL;Acc:C0P286]	[more]
anoh-2	9.746e-24	23.97	Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3]	[more]
anoh-2	1.022e-23	23.97	Anoctamin [Source:UniProtKB/TrEMBL;Acc:H2L2L3]	[more]

BLAST of Anoctamin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
subdued	1.039e-168	38.87	gene:FBgn0038721 transcript:FBtr0083806	[more]
subdued	1.039e-168	38.87	gene:FBgn0038721 transcript:FBtr0334921	[more]
subdued	3.490e-166	39.13	gene:FBgn0038721 transcript:FBtr0083805	[more]
subdued	2.083e-164	37.89	gene:FBgn0038721 transcript:FBtr0334922	[more]
subdued	2.557e-162	38.19	gene:FBgn0038721 transcript:FBtr0302492	[more]

BLAST of Anoctamin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ano11	0.000e+0	51.99	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
ano11	0.000e+0	51.99	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
si:dkey-83h2.5	0.000e+0	50.61	si:dkey-83h2.5 [Source:ZFIN;Acc:ZDB-GENE-131125-81...	[more]
ano11	0.000e+0	55.52	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
ano3	0.000e+0	41.47	anoctamin 3 [Source:ZFIN;Acc:ZDB-GENE-111031-3]	[more]

BLAST of Anoctamin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ANO4	1.096e-179	41.15	major histocompatibility complex class I-related g...	[more]
ANO4	9.231e-178	40.53	major histocompatibility complex class I-related g...	[more]
ANO5	4.029e-173	40.22	anoctamin 5 [Source:NCBI gene;Acc:100489787]	[more]
ANO5	1.206e-172	40.10	anoctamin 5 [Source:NCBI gene;Acc:100489787]	[more]
ANO5	1.958e-172	40.10	anoctamin 5 [Source:NCBI gene;Acc:100489787]	[more]

BLAST of Anoctamin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ano7	0.000e+0	47.55	anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714]	[more]
Ano7	0.000e+0	47.39	anoctamin 7 [Source:MGI Symbol;Acc:MGI:3052714]	[more]
Ano4	7.319e-179	39.95	anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344]	[more]
Ano4	7.319e-179	39.95	anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344]	[more]
Ano4	1.273e-178	39.95	anoctamin 4 [Source:MGI Symbol;Acc:MGI:2443344]	[more]

BLAST of Anoctamin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q14AT5\|ANO7_MOUSE	0.000e+0	47.39	Anoctamin-7 OS=Mus musculus OX=10090 GN=Ano7 PE=1 ...	[more]
sp\|Q6IWH7\|ANO7_HUMAN	0.000e+0	48.38	Anoctamin-7 OS=Homo sapiens OX=9606 GN=ANO7 PE=1 S...	[more]
sp\|Q6IFT6\|ANO7_RAT	0.000e+0	46.91	Anoctamin-7 OS=Rattus norvegicus OX=10116 GN=Ano7 ...	[more]
sp\|Q8C5H1\|ANO4_MOUSE	8.906e-178	39.95	Anoctamin-4 OS=Mus musculus OX=10090 GN=Ano4 PE=1 ...	[more]
sp\|Q9BYT9\|ANO3_HUMAN	3.452e-177	41.61	Anoctamin-3 OS=Homo sapiens OX=9606 GN=ANO3 PE=1 S...	[more]

BLAST of Anoctamin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267GKF1	0.000e+0	64.30	Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1...	[more]
A0A267H1A6	0.000e+0	64.30	Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1...	[more]
A0A267FA31	0.000e+0	64.30	Anoctamin OS=Macrostomum lignano OX=282301 GN=BOX1...	[more]
A0A4E0RHA9	0.000e+0	60.90	Anoctamin OS=Fasciola hepatica OX=6192 GN=D915_002...	[more]
A0A504YTV8	0.000e+0	60.52	Anoctamin OS=Fasciola gigantica OX=46835 GN=FGIG_0...	[more]

BLAST of Anoctamin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ano11	0.000e+0	52.00	anoctamin-7 [Source:NCBI gene;Acc:103029593]	[more]
ano11	0.000e+0	51.78	anoctamin-7 [Source:NCBI gene;Acc:103029593]	[more]
si:dkey-83h2.5	0.000e+0	50.00	anoctamin-7-like [Source:NCBI gene;Acc:103022406]	[more]
si:dkey-83h2.5	0.000e+0	50.00	anoctamin-7-like [Source:NCBI gene;Acc:103022406]	[more]
si:dkey-83h2.5	0.000e+0	49.68	anoctamin-7-like [Source:NCBI gene;Acc:103022406]	[more]

BLAST of Anoctamin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ano11	0.000e+0	51.07	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
ano11	7.794e-133	56.47	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
ano11	3.460e-131	58.20	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]
ENSPMAT00000000399.1	2.474e-130	38.87	pep scaffold:Pmarinus_7.0:GL477564:2673:43187:-1 g...	[more]
ano11	5.196e-128	56.20	anoctamin 11 [Source:ZFIN;Acc:ZDB-GENE-090313-245]	[more]

BLAST of Anoctamin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Anoctamin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO49855	0.000e+0	52.88	Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REV0]	[more]
EDO49854	0.000e+0	53.57	Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7REU8]	[more]
EDO48050	1.093e-165	38.07	Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU9]	[more]
EDO48048	1.323e-158	36.63	Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU7]	[more]
EDO48049	1.861e-152	39.16	Anoctamin [Source:UniProtKB/TrEMBL;Acc:A7RKU8]	[more]

BLAST of Anoctamin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-83h2.5	0.000e+0	48.87	anoctamin 7 [Source:NCBI gene;Acc:101162585]	[more]
ano3	0.000e+0	41.13	anoctamin 3 [Source:NCBI gene;Acc:101164148]	[more]
ano3	7.821e-174	40.36	anoctamin 3 [Source:NCBI gene;Acc:101164148]	[more]
ENSORLT00000011801.2	4.974e-173	39.61	anoctamin-1 [Source:NCBI gene;Acc:101173596]	[more]
ano5a	4.665e-170	38.23	anoctamin 5 [Source:NCBI gene;Acc:101164640]	[more]

BLAST of Anoctamin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000006381.1	0.000e+0	99.76	SMESG000006381.1	[more]
SMESG000052528.1	0.000e+0	60.43	SMESG000052528.1	[more]
SMESG000053932.1	0.000e+0	57.59	SMESG000053932.1	[more]
SMESG000033728.1	1.180e-104	37.48	SMESG000033728.1	[more]
SMESG000033732.1	1.499e-99	30.91	SMESG000033732.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025382 ID=SMED30025382|Name=Anoctamin|organism=Schmidtea mediterranea sexual|type=transcript|length=2731bp
ATATAAATCTTATATGAAAAAATCGATAAAAAGTAAAGATTATATATTTG
GTAGCACATAATAATTCCGTGAAATTGACCAATAGAAAAACAATTTCCCA
ACACAGAAGTTCTATAATTTTTTTTGAATATTTGCCTTCAATAAATTTAA
ACATTTTTTCATGATAAGGGAATCGTTCAGAAAATTGATAGGCAAAGCAA
ATGACTATGGGACTGTCAATGAGGAGGGCATTGAAGAAGAAGCAGCAGTA
CCTCCATTGGCATATTCTGGTTATTATTTTAATGATGGGAAAAGTAAAAT
AGATTTTATTTTGGCTTGGTCAGAAAAGGAAAAGGAACCTCATTCAAAAG
CTCTTTATAGAAAAAAGTTTGAAAGTAATTTAAAAAAAGCTGGACTGGAA
TTGGAAGAAGATTTTGATGAAACAGGGAAGTTTCATTATATAAAAATATA
TGTTCCTTGGGAAATAATGTGCCGTTTTGCTGAAAAGCTAGCACTTCGAG
CTCCATTGCAAGCACATCCAAATCCATCTGATGACTGGTCAATGAAAGCT
TTAAATTGCCTGCACATTCCTAACATAATGTACTTGGACGCTCCAAATAA
GCCGCCTGACTTCTATACTTGTGAATTCAAGCAGAGTAAAATTCACAGAT
TTCTCGGAAGTAACAATAAATTAACCTATTTTTCCTCCACACAACGACAC
CAAGTGGTAAACGAGATTCTGGAGACTCAATTATATGGAAGAAGAAGGAA
AGGAGAAATCGGAATTAAAAGAATGGTAGACGATGAAATCTATGATTCAG
CTTACCCATTGCATGAAGGTCCATATGAATGTTCAAAAACAGAACTGGAA
CAACCAGAGAAATTAAACAGTCGTCAAATTCTATACGAATATTGGGCTAG
ATATGGAAGGTGGTACCAATATCAACCGCTTGATCATATCAGAGAATATT
TCGGTGAAAAAATTGGATTTTATTTTGCTTGGATGGGTCTTTATACTGCA
TGGCTTCTCCCGGCTTCTATTATTGGAATATTTGTATTTTTGTATGGTGT
TTTTACATTCGATAGAAACATTTCAGCAAAAGAGATATGTGCAGGAAACA
ACTCTTTTTACATGTGCCCACTTTGCGATGAAAAAATCGGTTGCCAGTAT
TGGGAGCTTAAAGATGTTTGCATGTTCATCAAAATAGCTTATTTATTTGA
TCATCCTGGCACAATATTCTATTCAATATTCATGGCCATGTGGGCCGTCA
CATTTCTGGAGTATTGGAAGCGCAAGAATGCATCTTTAGCTCATCATTGG
GATGTTTTGGATTATGAAGAAGAAGAAGAAAGACCAAGAGCTCAATATGC
AGCTCTGTGTTCAATATTTCAAAAGAATCCTGTTACAGGAGTTATAGAGC
CTTATTTTCCTAAAGAAAGAAGGCTTCCAAGAATTCTTACTGGAATTGTG
TGTATCTTACTTATGATGACTGTGGTTATAATCTTTATAATTGCTGTAAT
AATATATCGGGTTCTCATTGAAATTCCAATGTTCCAAAATCCTTTGTTAA
GAAACAATGCTGTCACCTTTGCAAACGGAACTGCGGCAATCGTAAATTTG
GTTCTCATTATGTGCTTGGCAAAGGTCTATGAAATTATAGCTTTAAAATT
AACAGAATGGGAAATGCATCGAACACAATCTGATTTTGACAATCAATTAA
TATTCAAAGTATTTTTATTCCAATTTGTCAATTTTTACTCATCAATATTT
TACATTGCTTTTTTCAAAGGGCGATTTGTCGGTTATCCTGGAAATTATAG
TTATTTTTTTGGACTAAGAAACGAAGATTGCCAAAACGGTGGATGTTTAA
TTGAATTGGCCATGCAGCTGGCTATAATAATGGTTGGAAAGCAAATAATT
AGCAATATCCAAGAAGTCTTAGTACCAAAACTCCAAACATGGTTTTATCG
ATTTTCAAAGGGTCTAGGAGAACAAGTTCAGCATGATTCTTGCAGTAATT
CAGGATTAATCATTTATAAAGAAGACAACAAACTCATTCCATACGAAGGA
TTATTAGATGAATATCTTGAAATTGTTCTTCAATTTGGATTTATTACAAT
TTTTGTTGCTGCATTTCCATTAGCTCCATTTTTTGCTCTTTTAAATAACT
GGATGGAAATTCGGCTTGATGCTCAGAAATTAGTCTGTGAAACTCAAAGA
CCTGTTGCTGAAAGAGCGAAAGATATTGGAGTTTGGTTCGTTATTCTGGA
GTCCATCACCACCATTGCATGCATCAGTAATGCTTTTCTTTTGGCATTTA
CTTCAGAATTTTTGCCAAAACTTTATTATAGATACAGATTTGATTCACTC
GATGGTTACACTAATCATTCTTTATCGTGGTCACCCAAAAATTCTACAGT
AATTCCATGTCGCTATCCAGGATACCGTGACAATGACGGAATTTTAAAGC
AATACTTTTGGGAGCTTTTAGCTGTTCGCCTTGGATTCGTTATCGTGTTT
GAGCATACTGTGGCCGGAATTGGCAAATTGCTTGATCTGCTTATTCCAGA
TGTACCAAAAGAGTTATATATCAAGATAAAAAGAGAAACATACTTGGCTA
AACAAGCTTTGCAAGATGCAGATTTGATTACATGGGAGACTTTTGAAAAC
GAAAAAGAATAATTGTTATAAATTATAGCTGTGGATTTTACTTAATTTAA
ATTTTCATGAACTTAAGTGGTAAAGTATAAC

protein sequence of SMED30025382-orf-1

>SMED30025382-orf-1 ID=SMED30025382-orf-1|Name=SMED30025382-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=834bp
MIRESFRKLIGKANDYGTVNEEGIEEEAAVPPLAYSGYYFNDGKSKIDFI
LAWSEKEKEPHSKALYRKKFESNLKKAGLELEEDFDETGKFHYIKIYVPW
EIMCRFAEKLALRAPLQAHPNPSDDWSMKALNCLHIPNIMYLDAPNKPPD
FYTCEFKQSKIHRFLGSNNKLTYFSSTQRHQVVNEILETQLYGRRRKGEI
GIKRMVDDEIYDSAYPLHEGPYECSKTELEQPEKLNSRQILYEYWARYGR
WYQYQPLDHIREYFGEKIGFYFAWMGLYTAWLLPASIIGIFVFLYGVFTF
DRNISAKEICAGNNSFYMCPLCDEKIGCQYWELKDVCMFIKIAYLFDHPG
TIFYSIFMAMWAVTFLEYWKRKNASLAHHWDVLDYEEEEERPRAQYAALC
SIFQKNPVTGVIEPYFPKERRLPRILTGIVCILLMMTVVIIFIIAVIIYR
VLIEIPMFQNPLLRNNAVTFANGTAAIVNLVLIMCLAKVYEIIALKLTEW
EMHRTQSDFDNQLIFKVFLFQFVNFYSSIFYIAFFKGRFVGYPGNYSYFF
GLRNEDCQNGGCLIELAMQLAIIMVGKQIISNIQEVLVPKLQTWFYRFSK
GLGEQVQHDSCSNSGLIIYKEDNKLIPYEGLLDEYLEIVLQFGFITIFVA
AFPLAPFFALLNNWMEIRLDAQKLVCETQRPVAERAKDIGVWFVILESIT
TIACISNAFLLAFTSEFLPKLYYRYRFDSLDGYTNHSLSWSPKNSTVIPC
RYPGYRDNDGILKQYFWELLAVRLGFVIVFEHTVAGIGKLLDLLIPDVPK
ELYIKIKRETYLAKQALQDADLITWETFENEKE*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0061588	calcium activated phospholipid scrambling

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000099	neuron
PLANA:0000484	secretory system
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR031296	Anoctamin-7
IPR007632	Anoctamin
IPR032394	Anoct_dimer

Vocabulary: **molecular function**
Term	Definition
GO:0046983	protein dimerization activity

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR032394	Anoctamin, dimerisation domain	PFAM	PF16178	Anoct_dimer	coord: 39..257 e-value: 1.0E-67 score: 228.2
IPR007632	Anoctamin	PFAM	PF04547	Anoctamin	coord: 260..809 e-value: 4.0E-154 score: 513.8
IPR007632	Anoctamin	PANTHER	PTHR12308	NGEP-RELATED	coord: 58..824
IPR031296	Anoctamin-7	PANTHER	PTHR12308:SF22	ANOCTAMIN-7	coord: 58..824
None	No IPR available	TMHMM	TMhelix		coord: 638..660
None	No IPR available	TMHMM	TMhelix		coord: 270..292
None	No IPR available	TMHMM	TMhelix		coord: 689..711
None	No IPR available	TMHMM	TMhelix		coord: 350..369
None	No IPR available	TMHMM	TMhelix		coord: 468..490
None	No IPR available	TMHMM	TMhelix		coord: 426..448
None	No IPR available	TMHMM	TMhelix		coord: 513..535

Main menu

Anoctamin

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

blazegraph-runner