matrix metalloproteinase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025379 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 13
Homology
BLAST of matrix metalloproteinase vs. Ensembl Human
Match: MMP19 (matrix metallopeptidase 19 [Source:HGNC Symbol;Acc:HGNC:7165]) HSP 1 Score: 152.14 bits (383), Expect = 1.222e-40 Identity = 86/216 (39.81%), Postives = 121/216 (56.02%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKF-SRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL +YGY+ P S P+++++ ++ FQ+ + L V+G LD+ TR + PRCG++D + + G+W++K+L ++ + + L R A++ AF W+ V PLTF EV + L F R S FDG LAHA P G +HFD DE +TEG RG NLRI+AAHE+GHALGL HS S+ALMA Y GY Sbjct: 31 YLSQYGYLQKP-------LEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILN-LPSTLPPHTARAALRQAFQDWSNVAPLTFQEV-QAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGY 237
BLAST of matrix metalloproteinase vs. Ensembl Human
Match: MMP19 (matrix metallopeptidase 19 [Source:HGNC Symbol;Acc:HGNC:7165]) HSP 1 Score: 143.28 bits (360), Expect = 1.567e-37 Identity = 86/211 (40.76%), Postives = 113/211 (53.55%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKF-SRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL +YGY+ P S P+++++ ++ FQ+ + L V+G LD+ TR + PRCG++D + QK LKY + R A++ AF W+ V PLTF EV + L F R S FDG LAHA P G +HFD DE +TEG RG NLRI+AAHE+GHALGL HS S+ALMA Y GY Sbjct: 31 YLSQYGYLQKP-------LEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLED--------PFNQKTLKYLLL-----------ARAALRQAFQDWSNVAPLTFQEV-QAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGY 214
BLAST of matrix metalloproteinase vs. Ensembl Human
Match: MMP13 (matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]) HSP 1 Score: 141.354 bits (355), Expect = 1.762e-37 Identity = 86/201 (42.79%), Postives = 116/201 (57.71%), Query Frame = 1 Query: 466 VSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 +++ ++ Q GL+VTG LD+ T + PRCGV D+ ++F KW + NL Y+ V T +T S V +A + AF W++VTPL FT + D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL +VAAHE GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 64 MTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVN-YTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG-IADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTS-SSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 260
BLAST of matrix metalloproteinase vs. Ensembl Human
Match: MMP13 (matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]) HSP 1 Score: 140.969 bits (354), Expect = 1.003e-36 Identity = 86/201 (42.79%), Postives = 116/201 (57.71%), Query Frame = 1 Query: 466 VSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 +++ ++ Q GL+VTG LD+ T + PRCGV D+ ++F KW + NL Y+ V T +T S V +A + AF W++VTPL FT + D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL +VAAHE GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 64 MTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVN-YTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG-IADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTS-SSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 260
BLAST of matrix metalloproteinase vs. Ensembl Human
Match: MMP13 (matrix metallopeptidase 13 [Source:HGNC Symbol;Acc:HGNC:7159]) HSP 1 Score: 140.969 bits (354), Expect = 1.261e-36 Identity = 86/201 (42.79%), Postives = 116/201 (57.71%), Query Frame = 1 Query: 466 VSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 +++ ++ Q GL+VTG LD+ T + PRCGV D+ ++F KW + NL Y+ V T +T S V +A + AF W++VTPL FT + D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL +VAAHE GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 64 MTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVN-YTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG-IADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSS-KGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 260
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Match: zmp-3 (Matrix metalloproteinase-C [Source:UniProtKB/Swiss-Prot;Acc:G5EBU3]) HSP 1 Score: 137.502 bits (345), Expect = 2.219e-35 Identity = 88/241 (36.51%), Postives = 118/241 (48.96%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKE--VSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG----KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEER------GYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKN----MPLLNEDD 1044 + YL +GY+ P Q+ G + + E I+ FQ+ G+ TG LD T+ K L RCGV D G KW + L Y + + L+ VR AI A+ W++VTPL F+EV ++ ++F +H+D +PFDG G LAHA P G HFD DE +T + R +L VA HE GH LGL HS D A+MA FY TD + P L DD Sbjct: 57 ARSYLQTFGYVP-PSNSLQSRNGMAGDIQSAEQVFKSAIRKFQEFAGIAKTGFLDAATKAKMALSRCGVTDAPLALTSGSSQFKWSKTRLTYS-IESWSSDLSKDDVRRAISEAYGLWSKVTPLEFSEVPAGSTSDIKIRFGVRNHNDPWPFDGEGGVLAHATMPESGMFHFDDDENWTYKDARKIHNNEATDLLAVAIHEGGHTLGLEHSRDENAIMAPFYQKTTDSSGNYVYPNLKSDD 295
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Match: zmp-5 (Zinc MetalloProtease [Source:UniProtKB/TrEMBL;Acc:O17913]) HSP 1 Score: 108.227 bits (269), Expect = 8.340e-26 Identity = 60/149 (40.27%), Postives = 85/149 (57.05%), Query Frame = 1 Query: 604 WKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEV--FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNED 1041 W + + Y+ P +Q +++S + AF W E T L F V DE+K N + F+ H+D PFDG+ LAHAFFP G +HFD DE+++ + +G +L VA HEIGH+LGL HS + ++MA FY YT M L +D Sbjct: 39 WGKSVITYRLKQP-SQRMSLSQQKAVFARAFATWEEHTRLWFVAVDDEDEQKANIDIVFAAGDHEDGEPFDGKGNILAHAFFPRYGGDVHFDEDELWSANKTKGVDLYAVAVHEIGHSLGLKHSSNHLSIMAPFYKQYTGAVMHLHQDD 186
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Match: zmp-6 (MMP-like protein; Zinc MetalloProtease [Source:UniProtKB/TrEMBL;Acc:G5ECC4]) HSP 1 Score: 102.449 bits (254), Expect = 1.434e-24 Identity = 54/136 (39.71%), Postives = 77/136 (56.62%), Query Frame = 1 Query: 601 KWKQKNLKYKFVGPVTQYLT---MSAVREAIQSAFNYWAEVTPLTFTEV----FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALM 987 +WK+ L ++ TQ L + VR + AFN W+ V+ + F E+ ++ + + F + H D FPFDG+DG +AHAF+P DGR+HFD++E ++ G NL A HEIGH LGL HS D A M Sbjct: 48 RWKKHTLTWQLQ---TQNLLDPDVFIVRNTMHRAFNEWSTVSSVDFREIPPDLVTKQPPDIYIAFEKGEHSDGFPFDGQDGVVAHAFYPRDGRLHFDAEEQWSLNSVEGVNLFQTAVHEIGHLLGLEHSMDVRAAM 180
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Match: zmp-1 (Matrix metalloproteinase-A [Source:UniProtKB/Swiss-Prot;Acc:G5EGM1]) HSP 1 Score: 96.6709 bits (239), Expect = 1.588e-21 Identity = 75/223 (33.63%), Postives = 113/223 (50.67%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---------KWKQKNLKY--KFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGR--DGTLAHAFFPTDGRIHFDSDEIFTE---GEERGYN-LRIVAAHEIGHALGLPHSYDSEALMASF 996 +L KYGY++ + NQ L + +SD +K Q+ GL+ TG LDE T + E PRCG D++ KWK+K + Y K VG T+ +++ +R + A + W+E L E+ + N ++ S ++ +P R TLAHAFFPT+G+IH + F E G N L V AHE+GHALG HS D +++M ++ Sbjct: 29 FLQKYGYLTSGD--NQ--------LSSESLSDALKNMQRMAGLEETGELDERTIQMMERPRCGHPDVEDHQKSRGKRYAPPQFKWKEKIITYGCKAVGTSTR-ISLDDLRRTMHQAASQWSE---LADVEIVESSVKNPMMVISA-GRENHYPCTVRFDTKTLAHAFFPTNGQIHINDRVQFAMTNYTERMGANSLYSVVAHEMGHALGFSHSPDIDSVMFAY 236
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Match: zmp-2 (Matrix metalloproteinase-B [Source:UniProtKB/Swiss-Prot;Acc:O44836]) HSP 1 Score: 90.5077 bits (223), Expect = 1.949e-19 Identity = 84/273 (30.77%), Postives = 122/273 (44.69%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQ----------TRSMFGKWKQKN-----LKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVT--------PLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDG---------TLAHAFFP-----TDGRIHFDSDE---IFTEGEERGYNLRI---VAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPL----LNEDDK 1047 GQM KYGY+ G S+ P+E + FQ+ ++ TG +DE T + PRC D++ T S KW + LK+ ++ T + R+ ++ AF W+ + LTF E +++ + + ++ +H DE FDG +G LAH FFP +G IHFD E I + G N R V AHEIGHALGL HS ++ALM +Y KN+P+ L+ DDK Sbjct: 60 GQME--KYGYLK--------GIDHSS---PQEFRQALMFFQEVLEVEQTGNVDEMTVEAASKPRCTQTDVRQEQTKRTKRFTLSKRAKWAHASGQSVTLKW-YISDYTSDIDRLETRKVVEKAFKLWSSQSYIKNEKKVTLTFQEASSKDEADINILWAEGNHGDEHDFDGANGKIEGNKKENVLAHTFFPGYARPLNGDIHFDDAEDWEIDVDQVGHGSNKRFFPYVLAHEIGHALGLDHSQKADALMHPYY-----KNVPINEIQLDIDDK 313
BLAST of matrix metalloproteinase vs. Ensembl Fly
Match: Mmp1 (gene:FBgn0035049 transcript:FBtr0306656) HSP 1 Score: 143.28 bits (360), Expect = 1.301e-37 Identity = 105/263 (39.92%), Postives = 134/263 (50.95%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI----QTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ-------KNTTDLRS*TNFLCNSTIR 1107 ++YL ++GY+ + + S L D + I+ FQ GL +TG LD ET K LPRCGV+D +RS +W+ KNL YK + + L V I AF W+E T LTFT + +KF H D FDG+ GTLAHAFFP G HFD E++T G RG NL VAAHE GH+LGL HS S ALMA FY G+ + + L+EDDK + T LR TN +T R Sbjct: 33 AEIYLSQFGYLPASARNPAS----SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYK-ISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK-TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF--EPVFKLDEDDKAAIQSLYGRKTNQLRP-TNVYPATTQR 286
BLAST of matrix metalloproteinase vs. Ensembl Fly
Match: Mmp1 (gene:FBgn0035049 transcript:FBtr0304010) HSP 1 Score: 143.28 bits (360), Expect = 1.301e-37 Identity = 105/263 (39.92%), Postives = 134/263 (50.95%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI----QTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ-------KNTTDLRS*TNFLCNSTIR 1107 ++YL ++GY+ + + S L D + I+ FQ GL +TG LD ET K LPRCGV+D +RS +W+ KNL YK + + L V I AF W+E T LTFT + +KF H D FDG+ GTLAHAFFP G HFD E++T G RG NL VAAHE GH+LGL HS S ALMA FY G+ + + L+EDDK + T LR TN +T R Sbjct: 33 AEIYLSQFGYLPASARNPAS----SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYK-ISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK-TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF--EPVFKLDEDDKAAIQSLYGRKTNQLRP-TNVYPATTQR 286
BLAST of matrix metalloproteinase vs. Ensembl Fly
Match: Mmp1 (gene:FBgn0035049 transcript:FBtr0304009) HSP 1 Score: 143.28 bits (360), Expect = 1.430e-37 Identity = 105/263 (39.92%), Postives = 134/263 (50.95%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI----QTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ-------KNTTDLRS*TNFLCNSTIR 1107 ++YL ++GY+ + + S L D + I+ FQ GL +TG LD ET K LPRCGV+D +RS +W+ KNL YK + + L V I AF W+E T LTFT + +KF H D FDG+ GTLAHAFFP G HFD E++T G RG NL VAAHE GH+LGL HS S ALMA FY G+ + + L+EDDK + T LR TN +T R Sbjct: 33 AEIYLSQFGYLPASARNPAS----SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYK-ISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK-TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF--EPVFKLDEDDKAAIQSLYGRKTNQLRP-TNVYPATTQR 286
BLAST of matrix metalloproteinase vs. Ensembl Fly
Match: Mmp1 (gene:FBgn0035049 transcript:FBtr0304011) HSP 1 Score: 143.28 bits (360), Expect = 1.430e-37 Identity = 105/263 (39.92%), Postives = 134/263 (50.95%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI----QTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ-------KNTTDLRS*TNFLCNSTIR 1107 ++YL ++GY+ + + S L D + I+ FQ GL +TG LD ET K LPRCGV+D +RS +W+ KNL YK + + L V I AF W+E T LTFT + +KF H D FDG+ GTLAHAFFP G HFD E++T G RG NL VAAHE GH+LGL HS S ALMA FY G+ + + L+EDDK + T LR TN +T R Sbjct: 33 AEIYLSQFGYLPASARNPAS----SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYK-ISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK-TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF--EPVFKLDEDDKAAIQSLYGRKTNQLRP-TNVYPATTQR 286
BLAST of matrix metalloproteinase vs. Ensembl Fly
Match: Mmp1 (gene:FBgn0035049 transcript:FBtr0304006) HSP 1 Score: 143.28 bits (360), Expect = 1.533e-37 Identity = 105/263 (39.92%), Postives = 134/263 (50.95%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI----QTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ-------KNTTDLRS*TNFLCNSTIR 1107 ++YL ++GY+ + + S L D + I+ FQ GL +TG LD ET K LPRCGV+D +RS +W+ KNL YK + + L V I AF W+E T LTFT + +KF H D FDG+ GTLAHAFFP G HFD E++T G RG NL VAAHE GH+LGL HS S ALMA FY G+ + + L+EDDK + T LR TN +T R Sbjct: 33 AEIYLSQFGYLPASARNPAS----SGLHDQRTWVSAIEEFQSFAGLNITGELDAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYK-ISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRK-TSGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSALMAPFYRGF--EPVFKLDEDDKAAIQSLYGRKTNQLRP-TNVYPATTQR 286
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Match: mmp19 (matrix metallopeptidase 19 [Source:ZFIN;Acc:ZDB-GENE-100308-3]) HSP 1 Score: 157.918 bits (398), Expect = 4.645e-43 Identity = 98/220 (44.55%), Postives = 126/220 (57.27%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDD-EFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 Q YL ++GY+ P +N S+ D K + LFQ+ +GL VTG LD T K PRCGV+D + R G W++KNL Y+ T + SA + AI++AF YW++VTPL+FTE+ ++ S + D PFDG LAHA P G +HFD DE +TEG+ G NLRIVAAHEIGHALGL HS S ALMA+ Y GY Sbjct: 32 AQTYLRRFGYLDTP--LNPEAQRDSSEWDMKV---ALSLFQRVSGLPVTGNLDRATVFKMREPRCGVEDPFNQKSFKYRRFGGYWRKKNLTYRIYN-YTPDMGKSATQTAIRTAFKYWSDVTPLSFTEIHFGTAD---IRISFHKRDGCPSPFDGPGHVLAHAEAPPSGIVHFDEDEFWTEGKYYGSNLRIVAAHEIGHALGLGHSQYSSALMAAHYTGY 242
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Match: mmp13a (matrix metallopeptidase 13a [Source:ZFIN;Acc:ZDB-GENE-031202-2]) HSP 1 Score: 139.813 bits (351), Expect = 1.572e-36 Identity = 83/195 (42.56%), Postives = 114/195 (58.46%), Query Frame = 1 Query: 478 IKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDG---RIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 +K QQ LKV+G LD+ET + + PRCGV DI+ S F KWK+ L Y+ + T ++++ V ++I A WA+VTPL FT ++ + ++ F+ H D +PFDG +G LAHAF P +G HFD DE F+ + YNL +VAAHE GH+LGL HS D ALM Y Y D + +L DD Sbjct: 67 LKEMQQFFKLKVSGKLDQETLEVMKKPRCGVPDIKAYSTFAGDYKWKKHQLTYR-IENYTPDMSVAEVDDSISKALKVWADVTPLRFTRIY-SGTADIMISFATGDHRDGYPFDGPNGFLAHAFPPFEGIGGDAHFDDDETFSYRSPQYYNLFLVAAHEFGHSLGLEHSQDPGALMYPTYV-YRDVDRFVLPRDD 258
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Match: mmp19 (matrix metallopeptidase 19 [Source:ZFIN;Acc:ZDB-GENE-100308-3]) HSP 1 Score: 136.346 bits (342), Expect = 1.715e-35 Identity = 81/168 (48.21%), Postives = 101/168 (60.12%), Query Frame = 1 Query: 523 LDEETRKKFELPRCGVKD-IQTRSM----FGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDD-EFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 LD T K PRCGV+D +S FG W++KNL Y+ T + SA + AI++AF YW++VTPL+FTE+ ++ S + D PFDG LAHA P G +HFD DE +TEG+ G NLRIVAAHEIGHALGL HS S ALMA+ Y GY Sbjct: 1 LDRATVFKMREPRCGVEDPFNQKSFKYRRFGYWRKKNLTYRIYN-YTPDMGKSATQTAIRTAFKYWSDVTPLSFTEIHFGTAD---IRISFHKRDGCPSPFDGPGHVLAHAEAPPSGIVHFDEDEFWTEGKYYGSNLRIVAAHEIGHALGLGHSQYSSALMAAHYTGY 164
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Match: mmp13a (matrix metallopeptidase 13a [Source:ZFIN;Acc:ZDB-GENE-031202-2]) HSP 1 Score: 134.42 bits (337), Expect = 1.729e-34 Identity = 83/200 (41.50%), Postives = 115/200 (57.50%), Query Frame = 1 Query: 463 EVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDG---RIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 ++S +K QQ LKVTG LD+ET + + PRCGV DI+ S F KWK+ L Y+ + T ++++ V ++I A WA+VTPL FT ++ + ++ F+ H D +PFDG +G LAHA+ P +G HFD DE F+ + Y L VAAHE GH+LGL HS D ALM Y Y D + +L DD Sbjct: 63 DMSLRLKEMQQFFKLKVTGKLDQETLEVMKKPRCGVPDIKAYSTFPGDYKWKKHQLTYR-IENYTLDMSVAEVDDSISRALKVWADVTPLRFTRIY-SGTADIMIFFATGDHGDGYPFDGPNGFLAHAYPPYEGVGGDAHFDDDETFSYRSPQYYTLFSVAAHEFGHSLGLGHSRDPGALMYPTYV-YRDMDRFILPRDD 259
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Match: mmp20b (matrix metallopeptidase 20b (enamelysin) [Source:ZFIN;Acc:ZDB-GENE-100603-3]) HSP 1 Score: 131.724 bits (330), Expect = 1.883e-33 Identity = 83/202 (41.09%), Postives = 113/202 (55.94%), Query Frame = 1 Query: 469 SDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMF--GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQKNT 1059 S +K Q GL TG L+ +T PRCGV D++ S +WK+ + Y VG T L ++AV + I SA + WA+ +PLTF + + + +++F H D FPFDG DGTLAHAF P + G +HFD E++T G G+NL +VAAHE GHALGL HS E++M Y N+ L +ED NT Sbjct: 69 SSKLKNMQGFFGLNGTGTLNADTLAVMRTPRCGVSDVEDYSHRRGNRWKKNIITYG-VGRYTNDLPVNAVDDLISSALDVWAKASPLTFLRSYSHQ-ADIMVEFVGKEHGDFFPFDGPDGTLAHAFGPGEGIGGDVHFDEAEVWTAGYN-GFNLYVVAAHEFGHALGLKHSQLPESVMYPTYKRRKTHNL-LSSEDIININT 266
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Match: ENSXETT00000046574.1 (matrix metallopeptidase 8 [Source:NCBI gene;Acc:100494588]) HSP 1 Score: 149.828 bits (377), Expect = 4.044e-40 Identity = 95/216 (43.98%), Postives = 122/216 (56.48%), Query Frame = 1 Query: 415 KVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMF---GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 KV + G RS LLD I+ Q GL+VT L+EET + PRCGV DI S F WK+K+L Y+ + T +T + V AI+ AF W++V PLTFT ++D ++ + F+ H D PFDG G LAHAF P D G +HFD DE +T G G NL +VAAHE+GH+LGL HS D ALM Y Y + N L +DD Sbjct: 35 KVRKLGTSRSALLDK------IQKMQNFFGLEVTARLNEETIDVMKQPRCGVPDIARFSTFSGNAVWKKKDLTYRILN-YTPDMTRNDVDRAIEKAFKVWSDVVPLTFTRIYDR-VSDIEMLFAYRDHKDSLPFDGPSGILAHAFAPGDNIGGDVHFDEDEKWTSGSA-GTNLFLVAAHELGHSLGLDHSNDPNALMYPTYH-YINPNTFQLPQDD 240
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Match: ENSXETT00000046498.1 (matrix metalloproteinase-18-like [Source:NCBI gene;Acc:100489735]) HSP 1 Score: 148.673 bits (374), Expect = 7.809e-40 Identity = 85/195 (43.59%), Postives = 116/195 (59.49%), Query Frame = 1 Query: 478 IKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGK---WKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 I+ Q GL+VT +D+E + + PRCGV +I S F + WK+K+L Y+ + T ++T V AI+ AF W++V PLTFT ++D ++ + F+ H D FPFDG G LAH F P D G +HFD+DE +T G G NL +VAAHE+GH+LGL HS D ALM Y Y + N L+EDD Sbjct: 66 IRWMQDVLGLEVTARMDKENIEAMKQPRCGVPNIGRFSAFPRNPVWKKKDLTYRILN-YTSHMTRDEVDRAIEKAFKVWSDVVPLTFTRIYDR-VSDIEMSFASGDHKDAFPFDGPAGILAHTFAPGDNTGGDVHFDADETWTSGSA-GTNLFLVAAHELGHSLGLDHSNDPSALMYPTYH-YINPNTLQLSEDD 256
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Match: ENSXETT00000046522.1 (matrix metalloproteinase-18-like [Source:NCBI gene;Acc:100489735]) HSP 1 Score: 148.288 bits (373), Expect = 1.061e-39 Identity = 85/195 (43.59%), Postives = 116/195 (59.49%), Query Frame = 1 Query: 478 IKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGK---WKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 I+ Q GL+VT +D+E + + PRCGV +I S F + WK+K+L Y+ + T ++T V AI+ AF W++V PLTFT ++D ++ + F+ H D FPFDG G LAH F P D G +HFD+DE +T G G NL +VAAHE+GH+LGL HS D ALM Y Y + N L+EDD Sbjct: 37 IRWMQDVLGLEVTARMDKENIEAMKQPRCGVPNIGRFSAFPRNPVWKKKDLTYRILN-YTSHMTRDEVDRAIEKAFKVWSDVVPLTFTRIYDRV-SDIEMSFASGDHKDAFPFDGPAGILAHTFAPGDNTGGDVHFDADETWTSGSA-GTNLFLVAAHELGHSLGLDHSNDPSALMYPTYH-YINPNTLQLSEDD 227
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Match: ENSXETT00000046328.1 (matrix metalloproteinase-18-like [Source:NCBI gene;Acc:100489735]) HSP 1 Score: 148.288 bits (373), Expect = 2.273e-39 Identity = 85/195 (43.59%), Postives = 116/195 (59.49%), Query Frame = 1 Query: 478 IKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGK---WKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 I+ Q GL+VT +D+E + + PRCGV +I S F + WK+K+L Y+ + T ++T V AI+ AF W++V PLTFT ++D ++ + F+ H D FPFDG G LAH F P D G +HFD+DE +T G G NL +VAAHE+GH+LGL HS D ALM Y Y + N L+EDD Sbjct: 57 IRWMQDVLGLEVTARMDKENIEAMKQPRCGVPNIGRFSAFPRNPVWKKKDLTYRILN-YTSHMTRDEVDRAIEKAFKVWSDVVPLTFTRIYDR-VSDIEMSFASGDHKDAFPFDGPAGILAHTFAPGDNTGGDVHFDADETWTSGSA-GTNLFLVAAHELGHSLGLDHSNDPSALMYPTYH-YINPNTLQLSEDD 247
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Match: ENSXETT00000027926.1 (matrix metalloproteinase-18-like [Source:NCBI gene;Acc:100491214]) HSP 1 Score: 147.517 bits (371), Expect = 2.820e-39 Identity = 93/210 (44.29%), Postives = 119/210 (56.67%), Query Frame = 1 Query: 433 FGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMF---GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 F RS LLD I+ Q GL+VT L+EET + PRCGV DI S F WK+K+L Y+ + T +T + V AI+ AF W++V PLTFT ++D ++ + F+ H D PFDG G LAHAF P D G +HFD DE +T G G NL +VAAHE+GH+LGL HS D ALM Y Y + N L +DD Sbjct: 51 FNRSALLD------KIQKMQNFFGLEVTARLNEETIDVMKQPRCGVPDIARFSTFSGNAVWKKKDLTYRILN-YTPDMTRNDVDRAIEKAFKVWSDVVPLTFTRIYDR-VSDIEMLFAYRDHKDSLPFDGPSGILAHAFAPGDNIGGDVHFDEDERWTSGSA-GTNLFLVAAHELGHSLGLDHSNDPNALMYPTYH-YINPNTFQLPQDD 250
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Match: Mmp19 (matrix metallopeptidase 19 [Source:MGI Symbol;Acc:MGI:1927899]) HSP 1 Score: 160.229 bits (404), Expect = 1.327e-43 Identity = 89/218 (40.83%), Postives = 131/218 (60.09%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEV---FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL++YGY+ P + G L D +++ ++ FQ+ +GL ++G +D+ TR + + PRCG++D + + G W++KNL ++ V L++ VR A+ AF YW+ V PLTF EV + + + +F + S Y + FDG LAHA P G IHFD DE++TEG +G NLRI+AAHE+GHALGL HS ++ALMA YAGY Sbjct: 32 YLLQYGYLQKPLE----GADDFRLED---ITEALRTFQEASGLPISGQMDDATRARMKQPRCGLEDPFNQKSLKYLLLGHWRKKNLTFRIFN-VPSTLSLPRVRAALHQAFKYWSSVAPLTFREVKAGWADIRLSFHGRQSLYCSNT---FDGPGKVLAHADIPELGSIHFDKDELWTEGTYQGVNLRIIAAHEVGHALGLGHSRYTQALMAPVYAGY 238
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Match: Mmp13 (matrix metallopeptidase 13 [Source:MGI Symbol;Acc:MGI:1340026]) HSP 1 Score: 147.517 bits (371), Expect = 3.193e-39 Identity = 88/199 (44.22%), Postives = 115/199 (57.79%), Query Frame = 1 Query: 472 DGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 D ++ Q GL+VTG LD+ T PRCGV D+ ++F KW Q NL Y+ V T ++ S V +A + AF W++VTPL FT ++D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL IVAAHE+GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 67 DRLREMQSFFGLEVTGKLDDPTLDIMRKPRCGVPDVGEYNVFPRTLKWSQTNLTYRIVN-YTPDMSHSEVEKAFRKAFKVWSDVTPLNFTRIYDG-TADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSS-KGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 261
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Match: Mmp19 (matrix metallopeptidase 19 [Source:MGI Symbol;Acc:MGI:1927899]) HSP 1 Score: 140.969 bits (354), Expect = 4.718e-37 Identity = 75/170 (44.12%), Postives = 104/170 (61.18%), Query Frame = 1 Query: 523 LDEETRKKFELPRCGVKDIQTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEV---FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 +D+ TR + + PRCG++D + + G W++KNL ++ V L++ VR A+ AF YW+ V PLTF EV + + + +F + S Y + FDG LAHA P G IHFD DE++TEG +G NLRI+AAHE+GHALGL HS ++ALMA YAGY Sbjct: 1 MDDATRARMKQPRCGLEDPFNQKSLKYLLLGHWRKKNLTFRIFN-VPSTLSLPRVRAALHQAFKYWSSVAPLTFREVKAGWADIRLSFHGRQSLYCSNT---FDGPGKVLAHADIPELGSIHFDKDELWTEGTYQGVNLRIIAAHEVGHALGLGHSRYTQALMAPVYAGY 166
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Match: Mmp1b (matrix metallopeptidase 1b (interstitial collagenase) [Source:MGI Symbol;Acc:MGI:1933847]) HSP 1 Score: 140.198 bits (352), Expect = 1.204e-36 Identity = 85/205 (41.46%), Postives = 122/205 (59.51%), Query Frame = 1 Query: 460 KEV-SDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMF---GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFP---TDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 1053 KEV ++ ++ QQ GLKVTG D ET + + PRCGV D+ ++ +W + +L Y + T YL+ + V +AI AF W++VTPLTF VF+EE + +L F R H D + FDG AHAF P G +H+D D+ +T+ E +NL V AHE+GH+LGL HS D EALM Y +++K+ +LN+DD + Sbjct: 54 KEVMAEKLRQMQQLFGLKVTGNSDPETLRAMKKPRCGVPDVAPYAITHNNPRWTKTHLTYSILN-YTPYLSKAVVEDAIARAFRVWSDVTPLTFQRVFEEEG-DIVLSFHRGDHGDLYTFDGSKYHFAHAFLPGLGLGGNVHYDLDQKWTDNNE-DFNLFYVTAHELGHSLGLSHSNDEEALMFPSYT-WSNKDF-VLNQDDINR 253
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Match: Mmp24 (matrix metallopeptidase 24 [Source:MGI Symbol;Acc:MGI:1341867]) HSP 1 Score: 137.502 bits (345), Expect = 4.517e-35 Identity = 94/245 (38.37%), Postives = 130/245 (53.06%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD---IQTR------SMFG-KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEV------FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFP---TDGRIHFDSDEIFTEGEER--GYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNED 1041 GQ +L YGY+ +P + S L K + + QQ G+ VTG+LD+ T + + PRCGV D + R ++ G KW+QK++ Y + T + R+AI+ AF+ W +VTPLTF EV D ++ + ++ F+ H D PFDG G LAHA+FP G HFDSDE +T G G +L +VA HE+GHALGL HS D A+MA FY N L +D Sbjct: 54 GQNWLKSYGYL-LPYESRA-----SALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYS-IHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNFKLPQDD 291
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Match: sp|Q9JHI0|MMP19_MOUSE (Matrix metalloproteinase-19 OS=Mus musculus OX=10090 GN=Mmp19 PE=2 SV=1) HSP 1 Score: 160.229 bits (404), Expect = 9.279e-43 Identity = 89/218 (40.83%), Postives = 131/218 (60.09%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEV---FDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL++YGY+ P + G L D +++ ++ FQ+ +GL ++G +D+ TR + + PRCG++D + + G W++KNL ++ V L++ VR A+ AF YW+ V PLTF EV + + + +F + S Y + FDG LAHA P G IHFD DE++TEG +G NLRI+AAHE+GHALGL HS ++ALMA YAGY Sbjct: 32 YLLQYGYLQKPLE----GADDFRLED---ITEALRTFQEASGLPISGQMDDATRARMKQPRCGLEDPFNQKSLKYLLLGHWRKKNLTFRIFN-VPSTLSLPRVRAALHQAFKYWSSVAPLTFREVKAGWADIRLSFHGRQSLYCSNT---FDGPGKVLAHADIPELGSIHFDKDELWTEGTYQGVNLRIIAAHEVGHALGLGHSRYTQALMAPVYAGY 238
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Match: sp|Q99542|MMP19_HUMAN (Matrix metalloproteinase-19 OS=Homo sapiens OX=9606 GN=MMP19 PE=1 SV=1) HSP 1 Score: 152.14 bits (383), Expect = 5.869e-40 Identity = 86/216 (39.81%), Postives = 121/216 (56.02%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRS-----MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKF-SRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL +YGY+ P S P+++++ ++ FQ+ + L V+G LD+ TR + PRCG++D + + G+W++K+L ++ + + L R A++ AF W+ V PLTF EV + L F R S FDG LAHA P G +HFD DE +TEG RG NLRI+AAHE+GHALGL HS S+ALMA Y GY Sbjct: 31 YLSQYGYLQKP-------LEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILN-LPSTLPPHTARAALRQAFQDWSNVAPLTFQEV-QAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGY 237
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Match: sp|P33435|MMP13_MOUSE (Collagenase 3 OS=Mus musculus OX=10090 GN=Mmp13 PE=1 SV=1) HSP 1 Score: 147.517 bits (371), Expect = 2.234e-38 Identity = 88/199 (44.22%), Postives = 115/199 (57.79%), Query Frame = 1 Query: 472 DGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 D ++ Q GL+VTG LD+ T PRCGV D+ ++F KW Q NL Y+ V T ++ S V +A + AF W++VTPL FT ++D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL IVAAHE+GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 67 DRLREMQSFFGLEVTGKLDDPTLDIMRKPRCGVPDVGEYNVFPRTLKWSQTNLTYRIVN-YTPDMSHSEVEKAFRKAFKVWSDVTPLNFTRIYDG-TADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSS-KGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 261
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Match: sp|P23097|MMP13_RAT (Collagenase 3 (Fragment) OS=Rattus norvegicus OX=10116 GN=Mmp13 PE=1 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 7.458e-38 Identity = 88/199 (44.22%), Postives = 113/199 (56.78%), Query Frame = 1 Query: 472 DGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFP---TDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 D ++ Q GL VTG LD+ T PRCGV D+ ++F KW Q NL Y+ V T ++ S V +A + AF W++VTPL FT + D + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL IVAAHE+GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 61 DRLREMQSFFGLDVTGKLDDPTLDIMRKPRCGVPDVGVYNVFPRTLKWSQTNLTYRIVN-YTPDISHSEVEKAFRKAFKVWSDVTPLNFTRIHDG-TADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNLGGDAHFDDDETWTS-SSKGYNLFIVAAHELGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 255
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Match: sp|O77656|MMP13_BOVIN (Collagenase 3 OS=Bos taurus OX=9913 GN=MMP13 PE=2 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 7.654e-38 Identity = 94/234 (40.17%), Postives = 125/234 (53.42%), Query Frame = 1 Query: 367 FGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTD---GRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 F + YL Y Y P + + S + D ++ Q GL+VTG LD+ T + PRCGV D+ ++F KW + NL Y+ V T LT S V +A + AF W++VTPL FT + + + ++ F H D +PFDG G LAHAF P G HFD DE +T +GYNL +VAAHE GH+LGL HS D ALM Y YT K+ +L +DD Q Sbjct: 38 FAESYLKSYYYPQNPAGILKKTAASSVI-------DRLREMQSFFGLEVTGRLDDNTLDIMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVN-YTPDLTHSEVEKAFRKAFKVWSDVTPLNFTRIHNG-TADIMISFGTKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTS-SSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYT-YTGKSHFMLPDDDVQ 260
BLAST of matrix metalloproteinase vs. TrEMBL
Match: A0A090C5X6 (Matrix metalloproteinase OS=Schmidtea mediterranea OX=79327 GN=mmpb PE=2 SV=1) HSP 1 Score: 518.464 bits (1334), Expect = 1.780e-177 Identity = 264/264 (100.00%), Postives = 264/264 (100.00%), Query Frame = 1 Query: 262 MNPVFYRLIKWILIFGNXXXXXXXXXXXXXXXRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 1053 MNPVFYRLIKWILIFGNVVSVSVAATTPSPSSRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK Sbjct: 1 MNPVFYRLIKWILIFGNVVSVSVAATTPSPSSRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 264 HSP 2 Score: 59.6918 bits (143), Expect = 7.906e-6 Identity = 45/46 (97.83%), Postives = 46/46 (100.00%), Query Frame = 2 Query: 1049 KKIQQIYGRKPISSVTPRSEKSTKRRRMXXXXXXXXXXXXXXQDLV 1186 +KIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV Sbjct: 263 QKIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV 308
BLAST of matrix metalloproteinase vs. TrEMBL
Match: W5M9J9 (Matrix metallopeptidase 19 OS=Lepisosteus oculatus OX=7918 PE=3 SV=1) HSP 1 Score: 177.563 bits (449), Expect = 4.845e-47 Identity = 100/227 (44.05%), Postives = 132/227 (58.15%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMF-----GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 YL +YGY+S P +GF P+E+ + +++FQ+ L VTG +D+ T PRCG++D + F G+W++KNL Y+ + T L ++ R AIQSAF+YW+EV PLTF EV + + + F R SH FDG LAHA P G +HFD DE +TEG RG NLRI+AAHEIGHALGL HS ALM Y GY K+ L+ DD Sbjct: 34 YLKQYGYLSTPLDPQASGF------QPEEIEEALRVFQRVTQLPVTGTIDKATLAMMRRPRCGIEDPFNQKTFKYRLLGRWRKKNLTYR-IHNHTPDLGLAETRAAIQSAFHYWSEVAPLTFQEV-TGGRADIKISFHRRSHACSVAFDGPGRVLAHADVPESGIVHFDEDEYWTEGTSRGANLRIIAAHEIGHALGLGHSQYPSALMGPVYNGY--KSNFWLHPDD 250
BLAST of matrix metalloproteinase vs. TrEMBL
Match: A0A3P9ANV0 (ZnMc domain-containing protein OS=Esox lucius OX=8010 PE=3 SV=1) HSP 1 Score: 175.252 bits (443), Expect = 3.928e-46 Identity = 92/218 (42.20%), Postives = 128/218 (58.72%), Query Frame = 1 Query: 373 QMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 Q+YL YGY+ P G + + +E+++ +K+FQ+ L V+G L+E T + PRCG++D ++ R + W++K L Y+ T L ++ R A+QSAF YW+EV+PLTF EV + + + F + PFDG G LAHA P G +HFD DE++TEG+ G NLRIVAAHEIGHALGL HS S ALM Y+GY Sbjct: 18 QVYLRTYGYLHRP-----LDSGMNHVHQAEEITEALKIFQKATNLTVSGTLNEATMSMMKQPRCGIRDSFSDKSLKYRVLGSIWRKKRLTYRIYSYTTD-LGLAKTRAALQSAFRYWSEVSPLTFQEVLFPGRADIKISFHKKDRSCPVPFDGPGGVLAHADNPESGIVHFDEDELWTEGKSSGPNLRIVAAHEIGHALGLGHSQYSNALMGPVYSGY 229
BLAST of matrix metalloproteinase vs. TrEMBL
Match: A0A3B4BFY4 (ZnMc domain-containing protein OS=Periophthalmus magnuspinnatus OX=409849 PE=3 SV=1) HSP 1 Score: 174.096 bits (440), Expect = 1.020e-45 Identity = 96/220 (43.64%), Postives = 126/220 (57.27%), Query Frame = 1 Query: 367 FGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 Q YL KYGY+ IP + P+E+S+ ++ FQ+ L V+GI D T + + PRCG++D ++ R M G+WK+K L Y+ + L R AIQ+AF YW+EV+PL F E++ K + + F R PFDGR LAHA P G IHFD+DE++TEG G NLRIVAAHEIGHALGL HS ALM Y+GY Sbjct: 20 LNQAYLQKYGYLHIPLSAKPLNY------RPEELSNALRTFQKTTNLSVSGIFDVATLRMMDKPRCGLEDSGSDETLRYRVM-GQWKKKFLTYRIYNFASD-LGQGKTRSAIQAAFRYWSEVSPLRFRELY-SGKADIKISFHRKEKSCPVPFDGRGHVLAHADAPESGLIHFDADELWTEGRSSGSNLRIVAAHEIGHALGLGHSQYYSALMGPVYSGY 230
BLAST of matrix metalloproteinase vs. TrEMBL
Match: A0A3P8Z9P3 (ZnMc domain-containing protein OS=Esox lucius OX=8010 PE=3 SV=1) HSP 1 Score: 172.94 bits (437), Expect = 2.348e-45 Identity = 91/217 (41.94%), Postives = 127/217 (58.53%), Query Frame = 1 Query: 376 MYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 +YL YGY+ P G + + +E+++ +K+FQ+ L V+G L+E T + PRCG++D ++ R + W++K L Y+ T L ++ R A+QSAF YW+EV+PLTF EV + + + F + PFDG G LAHA P G +HFD DE++TEG+ G NLRIVAAHEIGHALGL HS S ALM Y+GY Sbjct: 33 VYLRTYGYLHRP-----LDSGMNHVHQAEEITEALKIFQKATNLTVSGTLNEATMSMMKQPRCGIRDSFSDKSLKYRVLGSIWRKKRLTYRIYSYTTD-LGLAKTRAALQSAFRYWSEVSPLTFQEVLFPGRADIKISFHKKDRSCPVPFDGPGGVLAHADNPESGIVHFDEDELWTEGKSSGPNLRIVAAHEIGHALGLGHSQYSNALMGPVYSGY 243
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Match: ENSAMXT00000007864.2 (matrix metalloproteinase-19 [Source:NCBI gene;Acc:103027674]) HSP 1 Score: 156.762 bits (395), Expect = 8.973e-43 Identity = 97/233 (41.63%), Postives = 133/233 (57.08%), Query Frame = 1 Query: 373 QMYLVKYGYI--SIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD-IQTRSM----FGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDD--EFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 Q+YL KYGY+ S+ +Q G K++S+ +++FQ+ L V+G LD T + PRCG+KD R++ G W++K L Y+ + L ++ R AIQ+AF YW+EV+PL F E+ K + +K S + D PFDG LAHA P G +HFD +E++TEG+ G NLRIVAAHEIGHALGL HS ALM Y GY +N L+ DD Sbjct: 11 QVYLTKYGYLPTSLHHPKDQDG-------QVKQISEALRVFQKVMELPVSGRLDNATLVMMKQPRCGLKDPFNNRTLKYRVLGHWRKKTLSYRIYNHASS-LGVAKTRAAIQTAFRYWSEVSPLRFHEL---NKGHPDIKISFHGRDRVCPVPFDGPGEVLAHADSPESGLVHFDEEELWTEGKSTGSNLRIVAAHEIGHALGLGHSQYRSALMGPVYTGY--RNNFRLHPDD 230
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Match: ENSAMXT00000030273.1 (matrix metalloproteinase-19 [Source:NCBI gene;Acc:103027674]) HSP 1 Score: 154.451 bits (389), Expect = 6.179e-42 Identity = 96/232 (41.38%), Postives = 132/232 (56.90%), Query Frame = 1 Query: 376 MYLVKYGYI--SIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD-IQTRSM----FGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDD--EFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 +YL KYGY+ S+ +Q G K++S+ +++FQ+ L V+G LD T + PRCG+KD R++ G W++K L Y+ + L ++ R AIQ+AF YW+EV+PL F E+ K + +K S + D PFDG LAHA P G +HFD +E++TEG+ G NLRIVAAHEIGHALGL HS ALM Y GY +N L+ DD Sbjct: 39 VYLTKYGYLPTSLHHPKDQDG-------QVKQISEALRVFQKVMELPVSGRLDNATLVMMKQPRCGLKDPFNNRTLKYRVLGHWRKKTLSYRIYNHASS-LGVAKTRAAIQTAFRYWSEVSPLRFHEL---NKGHPDIKISFHGRDRVCPVPFDGPGEVLAHADSPESGLVHFDEEELWTEGKSTGSNLRIVAAHEIGHALGLGHSQYRSALMGPVYTGY--RNNFRLHPDD 257
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Match: mmp19 (matrix metalloproteinase-19 [Source:NCBI gene;Acc:103033524]) HSP 1 Score: 154.066 bits (388), Expect = 8.706e-42 Identity = 90/219 (41.10%), Postives = 127/219 (57.99%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDE---FPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL ++GY+ P + +E+ + + LFQ+ + L +TG +DE T + PRCGV+D ++ R+ G W++++L Y+ T + +A + AI+SAF YW++VTPL+F E+ D + + + F H E PFDG LAHA PT G +HFD DE +TEG+ G NLRIVAAHEIGHALGL HS ALMA+ Y GY Sbjct: 35 YLKQFGYLDTPLDLEVQAHWSD-----EEIKEALSLFQRVSELPITGQIDEATIGQMRQPRCGVEDPFNQKSMRYRTFGGVWRRRSLTYRIYN-YTPDMGKAATQRAIRSAFKYWSDVTPLSFKEI-DYGRADIRISF----HTREGCPSPFDGPGHVLAHAEAPTSGIVHFDEDEFWTEGKYYGSNLRIVAAHEIGHALGLGHSQYKSALMAAHYTGY 242
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Match: mmp19 (matrix metalloproteinase-19 [Source:NCBI gene;Acc:103033524]) HSP 1 Score: 154.066 bits (388), Expect = 8.706e-42 Identity = 90/219 (41.10%), Postives = 127/219 (57.99%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDE---FPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL ++GY+ P + +E+ + + LFQ+ + L +TG +DE T + PRCGV+D ++ R+ G W++++L Y+ T + +A + AI+SAF YW++VTPL+F E+ D + + + F H E PFDG LAHA PT G +HFD DE +TEG+ G NLRIVAAHEIGHALGL HS ALMA+ Y GY Sbjct: 35 YLKQFGYLDTPLDLEVQAHWSD-----EEIKEALSLFQRVSELPITGQIDEATIGQMRQPRCGVEDPFNQKSMRYRTFGGVWRRRSLTYRIYN-YTPDMGKAATQRAIRSAFKYWSDVTPLSFKEI-DYGRADIRISF----HTREGCPSPFDGPGHVLAHAEAPTSGIVHFDEDEFWTEGKYYGSNLRIVAAHEIGHALGLGHSQYKSALMAAHYTGY 242
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Match: MMP1 (collagenase 3-like [Source:NCBI gene;Acc:111195015]) HSP 1 Score: 150.599 bits (379), Expect = 1.766e-40 Identity = 92/230 (40.00%), Postives = 126/230 (54.78%), Query Frame = 1 Query: 373 QMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT---DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 Q YL K+ ++ E+ GR+ +S+ I Q+ GL VTG +D+ET + + PRCGV ++ + FG KW++ L Y+ V T L+ + V ++ A WA VTPL FT + + ++ F SH D +PFDG GTLAHAF P+ G HFD DE+FT +GY L +VAAHE GH+LGL HS D ALM Y+ Y D N +L DD Sbjct: 35 QSYLKKF--YNLTEQTGPHSKGRT-----NHMSEKIAEMQKFFGLTVTGTVDQETLQVMKKPRCGVPEVAQYTTFGAGLKWQKNQLTYRIVN-YTPDLSQAEVDSVLEKALQVWARVTPLKFTRI-SSGDADIMISFGAGSHGDYYPFDGPGGTLAHAFAPSAGIGGDAHFDEDELFTSSSTKGYLLFLVAAHEFGHSLGLSHSSDPGALMYPTYS-YRDPNTFVLPRDD 254
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Match: mmp19 (matrix metallopeptidase 19 [Source:ZFIN;Acc:ZDB-GENE-100308-3]) HSP 1 Score: 134.806 bits (338), Expect = 2.037e-35 Identity = 72/151 (47.68%), Postives = 90/151 (59.60%), Query Frame = 1 Query: 574 DIQTRSMF---GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDK 1017 D T S F G+W++ L Y F+ +T L + V++ I AF+ W+ VTPL F E K + ++FSR H D PFDG LAHA+FP DGR HFD DE ++EG +G NL IVA HE GH LGL HS + ALMA FY GY K Sbjct: 96 DKPTASCFVSGGRWRKTTLAYHFLN-LTPDLKGNEVKKIIARAFHEWSRVTPLRFYETPTSPKADIHIQFSRLQHGDFAPFDGPGRVLAHAYFPEDGRAHFDEDEQWSEGTAQGINLHIVATHEFGHLLGLGHSKEQAALMAPFYMGYRPK 245
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Match: mmp19 (matrix metallopeptidase 19 [Source:ZFIN;Acc:ZDB-GENE-100308-3]) HSP 1 Score: 132.88 bits (333), Expect = 3.254e-35 Identity = 68/140 (48.57%), Postives = 86/140 (61.43%), Query Frame = 1 Query: 598 GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDK 1017 G+W++ L Y F+ +T L + V++ I AF+ W+ VTPL F E K + ++FSR H D PFDG LAHA+FP DGR HFD DE ++EG +G NL IVA HE GH LGL HS + ALMA FY GY K Sbjct: 3 GRWRKTTLAYHFLN-LTPDLKGNEVKKIIARAFHEWSRVTPLRFYETPTSPKADIHIQFSRLQHGDFAPFDGPGRVLAHAYFPEDGRAHFDEDEQWSEGTAQGINLHIVATHEFGHLLGLGHSKEQAALMAPFYMGYRPK 141
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001966.1 (pep scaffold:Pmarinus_7.0:GL476330:946825:981591:-1 gene:ENSPMAG00000001746.1 transcript:ENSPMAT00000001966.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.191 bits (339), Expect = 3.933e-35 Identity = 89/248 (35.89%), Postives = 128/248 (51.61%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGR-STLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG------------KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEE------KTNFILKFSRYSHDDEFPFDGRDGTLAHAFFP---TDGRIHFDSDEIFT--EGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 +L +YGY+ G R ST+ P +S + Q+ G+ VTG +D +T + + PRCGV D + + +W+QK++ Y T + + R A++ AF+ W +VTPL F EV + E + + ++ F+ +H D PFDG G LAHA+FP G HFD+DE +T G G +L +VA HE+GHALGL HS D A+MA FY Y D +L DD Q Sbjct: 1 WLQRYGYLP-------GGDARMSTIRSPGVMSAAVSAMQRFYGINVTGTVDADTLRWMKRPRCGVPDRIDQGLQAGLRRKRYALTGQRWQQKHITYSLQN-YTPKVGEADTRRALRRAFDVWQQVTPLVFEEVSNHEIRSSRREADIMIFFASGNHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDADEPWTLGNGNAGGNDLFLVAIHELGHALGLEHSNDPAAIMAPFYQ-YMDTENFVLPRDDLQ 239
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Match: MMP14 (matrix metallopeptidase 14 [Source:HGNC Symbol;Acc:HGNC:7160]) HSP 1 Score: 130.568 bits (327), Expect = 1.946e-34 Identity = 93/248 (37.50%), Postives = 127/248 (51.21%), Query Frame = 1 Query: 373 QMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFG------------KWKQKNLKY---KFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKT----NFILKFSRYSHDDEFPFDGRDGTLAHAFFP---TDGRIHFDSDEIFTEG--EERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 Q +L +YGY+ P Q RS + +S+ + Q G+ VTG +DE TR+ + PRCGV D ++ KW +++ Y + V +Y T A+R A F+ W VTPLTFT+V + + + I+ F+ H D PFDG G LAHA+FP G HFD+DE +T G + G +L IVA HE+GHALGL HS D A+MA FY Y D + L DD Sbjct: 3 QTWLQQYGYL--PAGDLQMATYRSGQM----LSEAVSSMQAFYGIPVTGTMDELTRQWMQKPRCGVPDRYGTTVTAGSRHKRYAINHLKWHHQHITYDIQNYTPKVGEYETHQAIRHA----FDVWQAVTPLTFTQVSGRDGSGNDADIIIFFASGYHGDRSPFDGVGGFLAHAYFPGKGIGGDTHFDADEPWTLGGHDYTGNDLFIVAVHELGHALGLEHSNDPSAIMAPFYQ-YMDTDDFQLPYDD 239
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005331.1 (pep scaffold:Pmarinus_7.0:GL476741:9169:28768:-1 gene:ENSPMAG00000004733.1 transcript:ENSPMAT00000005331.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.013 bits (297), Expect = 2.213e-30 Identity = 69/168 (41.07%), Postives = 100/168 (59.52%), Query Frame = 1 Query: 562 CGVKDIQTRSMF---GKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDG---RIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDK 1047 CGV + + S++ KW +KNL Y+FV ++ +A+ AF+ W V+ LTF ++ E + + ++ F R H DEFPFDG G LAHA+ P+ G +HFD +E ++ G GYNLR+VAAHE+GHALGL HS + ++M Y + P L+EDDK Sbjct: 11 CGVPNPNSFSLYPSRNKWLKKNLTYRFVN-YPSGMSRERAEDALAEAFDLWRSVSTLTF-QMLREGEADIMISFERRYHGDEFPFDGPHGVLAHAYEPSPGLGGDLHFDDEEQWSVGLI-GYNLRVVAAHELGHALGLQHSNERGSIMNPSYQVWIH---PYLSEDDK 172
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Match: EDO41167 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S526]) HSP 1 Score: 155.606 bits (392), Expect = 1.482e-42 Identity = 95/236 (40.25%), Postives = 130/236 (55.08%), Query Frame = 1 Query: 373 QMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRS-----------MFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPT-DGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 Q YL +YGY+ P + +TG RS +++S I+ FQ+ GL+ TGI+D T+ K E PRCG+ DI S +W++ + Y+F L+ +AVR A W++ L E D K +F + F+ Y H D PFDG GTLAHAFFP G +HFD E +TEG++ G NL VAAHE+GH LGL HS +++MA +Y GY K L+EDD Sbjct: 24 QDYLTRYGYLDAPNR--KTGAIRSR----QDLSRAIRQFQRYTGLQETGIMDAATKSKMEQPRCGLPDIVGTSENARRKRRYALQGSRWEKSEITYRFAS-YGNDLSRTAVRRIFARAAKLWSDKMQLNIKETSDA-KADFTVSFNSYDHGDGDPFDGPGGTLAHAFFPQYGGDLHFDDSETYTEGKDAGVNLLFVAAHELGHTLGLSHSDVWQSVMAPYYPGY--KANLELHEDD 249
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Match: EDO34801 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNA9]) HSP 1 Score: 136.732 bits (343), Expect = 2.688e-38 Identity = 80/197 (40.61%), Postives = 110/197 (55.84%), Query Frame = 1 Query: 475 GIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQ---TRSMFG----KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDE-FPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNED 1041 I+LFQ+ L VTG LDE + KK RCG DI+ S + KW + +L Y F +T + + AF+ W++ + LTFT V D + + F +H + +PFDG+ LAHAFFPTDG +HFD DE FT+G G NL VA HEIGH LG+ HS ++ ++M Y+GY D N+ L +D Sbjct: 1 AIELFQRYMHLPVTGQLDEASIKKMHQKRCGFPDIEEDEDTSEYAVAPTKWNKTSLTYAFEN-YGDDMTSATQENILARAFSMWSDNSNLTFTLVSDASNADIKIAFVTGTHSNCIYPFDGQGSVLAHAFFPTDGSLHFDDDEDFTDGVATGTNLLAVAVHEIGHILGVGHSSETNSVMNPNYSGY-DPNLALHADD 195
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Match: EDO49974 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RET8]) HSP 1 Score: 136.346 bits (342), Expect = 5.140e-38 Identity = 80/223 (35.87%), Postives = 116/223 (52.02%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSM-FGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEF-PFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNED 1041 +L KY Y+S + N ++ I+++Q+ L V+G LD T+ + PRCGV D++ GKW +L Y F T LT + + I AF W++V+P FT D+ K + + F +H + FDG +AHA++P+DGR+HFD DE FT+G G NL +A HEIGH LG+ HS D ++M Y Y N+ L ED Sbjct: 3 FLKKYHYLSSHVRGNH------------DMQTAIEIYQRYMNLPVSGRLDNATQVSMDEPRCGVPDLEIDDPGLGKWLNTSLLYAF-ETYTADLTQTVQKAVIAKAFKMWSDVSPFIFTLTTDKTKAHIKILFGTNTHGNCLKAFDGPGKVIAHAYYPSDGRLHFDDDETFTDGVNTGTNLLAIAVHEIGHILGIAHSTDKNSVMYPKYETY-KPNLQLHAED 211
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Match: EDO38677 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCE7]) HSP 1 Score: 134.42 bits (337), Expect = 1.918e-37 Identity = 86/219 (39.27%), Postives = 110/219 (50.23%), Query Frame = 1 Query: 373 QMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQT-RSMFG-KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSH----DDE----FPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFY 999 Q YL ++ YIS N V ++ FQ GL VTG +D T + ++PRCG+ D R G KW +K+L Y Q L+ S A +YWA V+ LTF+ D E + + F SH D E +PFDG G LAHAFFP +GR HFD DE FT+G G NL VA HE GH+LGL HS +A+M +Y Sbjct: 1 QKYLNQFHYISPARSGNHN------------VKTALEKFQSFAGLPVTGEIDAATIAQMKMPRCGMPDDNYFRYKLGSKWNKKHLTYHISH--GQDLSSSVQDRVFAKALDYWARVSGLTFSRTMDGENADLKISFGPKSHGGTHDPEGTCSYPFDGPGGVLAHAFFPRNGRAHFDEDEDFTDGTYEGTNLLWVATHEFGHSLGLHHSDVRDAVMYPYY 205
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Match: EDO29931 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T286]) HSP 1 Score: 131.724 bits (330), Expect = 2.898e-36 Identity = 78/212 (36.79%), Postives = 106/212 (50.00%), Query Frame = 1 Query: 391 YGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDE------FPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 Y YIS NQ +V IK FQ+ GL+VTG LD+ T + ++PRCG D+ +W + L Y + L S + A +W++ + L+F+ V D K + + F SH+ PFDG LAHA+FP++GR HFD DE +T+G G NL VA HE GHALGL HS A+M +Y GY Sbjct: 1 YNYISNSRSGNQ------------DVETAIKNFQRFAGLEVTGELDDATIAQMKMPRCGDADVDDNG--DRWNKNALTYHL--SYGKDLPNSVQDRVFEKALKFWSDGSALSFSRVSDVSKADLKISFGSRSHNGPGESRCGSPFDGPGRVLAHAYFPSNGRCHFDEDERYTDGASSGINLLWVATHEFGHALGLHHSDVRNAVMYPYYTGY 196
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Match: mmp19 (matrix metallopeptidase 19 [Source:NCBI gene;Acc:101162361]) HSP 1 Score: 161.77 bits (408), Expect = 1.079e-44 Identity = 95/221 (42.99%), Postives = 124/221 (56.11%), Query Frame = 1 Query: 370 GQMYLVKYGYISIPEKVNQTGFGRSTLLDP---KEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD-----IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 + YL +YGY++ P DP +EV + +++FQ+ N L +G LDE T PRCG++D + + G+W++KNL Y+ T + S V AI+SAF YW++VTPLTF EV D + + + F + PFDGR LAHA P G +HFD DE +TE G NLRIVAAHEIGHALGL HS ALMA YAGY Sbjct: 33 AKAYLRQYGYLNDPANPE----------DPFYLEEVIEALRVFQRVNDLPPSGELDEATLAVMRQPRCGMEDPFNKKLHKFRIMGRWRKKNLTYRIYN-YTPDMKQSDVSAAIRSAFKYWSDVTPLTFKEV-DYGRADIKISFHKKDGHCSVPFDGRGHVLAHAESPESGIVHFDEDEFWTEQSYYGTNLRIVAAHEIGHALGLGHSQFRSALMAPVYAGY 241
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Match: ENSORLT00000039885.1 (matrix metalloproteinase-19-like [Source:NCBI gene;Acc:101156575]) HSP 1 Score: 159.844 bits (403), Expect = 5.945e-44 Identity = 85/216 (39.35%), Postives = 126/216 (58.33%), Query Frame = 1 Query: 379 YLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 YL K+GY+ IP + P+++++ +++FQ+ ++++G LD T RCG++D + R M G W++K L Y+ T +L + R+AIQSAF W++V+PL F E+ + + + + F R PFDGR LAHA P G +HFD+DE++TEG+ G++LRIVAAHEIGHALGL HS ALM Y+GY Sbjct: 33 YLQKFGYLHIPLDSKDVNY------PPEKIAEALRIFQKVTNMQMSGNLDSATLAMMNRARCGLEDSFIDNSLSYRVM-GYWRKKMLTYRIYN-YTPHLGLEKTRQAIQSAFKLWSDVSPLRFKEL-QQGRPDIKISFHRKDKSCPVPFDGRGRVLAHADAPESGIVHFDADELWTEGKSHGFSLRIVAAHEIGHALGLAHSQYYSALMGPIYSGY 239
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Match: ENSORLT00000018958.2 (matrix metalloproteinase-19-like [Source:NCBI gene;Acc:101156575]) HSP 1 Score: 152.14 bits (383), Expect = 1.852e-41 Identity = 78/190 (41.05%), Postives = 116/190 (61.05%), Query Frame = 1 Query: 457 PKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD------IQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGY 1008 P+++++ +++FQ+ ++++G LD T RCG++D + R M G W++K L Y+ T +L + R+AIQSAF W++V+PL F E+ + + + + F R PFDGR LAHA P G +HFD+DE++TEG+ G++LRIVAAHEIGHALGL HS ALM Y+GY Sbjct: 13 PEKIAEALRIFQKVTNMQMSGNLDSATLAMMNRARCGLEDSFIDNSLSYRVM-GYWRKKMLTYRIYN-YTPHLGLEKTRQAIQSAFKLWSDVSPLRFKEL-QQGRPDIKISFHRKDKSCPVPFDGRGRVLAHADAPESGIVHFDADELWTEGKSHGFSLRIVAAHEIGHALGLAHSQYYSALMGPIYSGY 199
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Match: ENSORLT00000025461.2 (collagenase 3-like [Source:NCBI gene;Acc:101159886]) HSP 1 Score: 146.362 bits (368), Expect = 4.987e-39 Identity = 86/202 (42.57%), Postives = 116/202 (57.43%), Query Frame = 1 Query: 436 GRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTR--SMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDG---RIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYA-GYTD 1014 G S +S ++ Q+ GL+VTG LD +T + + PRCG+ DI S FG KW++ L Y+ V T ++ + V+++IQ A WA VTPL FT + + ++ F R +H D +PFDG GTLAHAF P+ G +HFD DE FT +GY L +VAAHE GH+LGL HS D ALM Y+ GY D Sbjct: 46 GPSARWGVSPMSRRLREMQRFFGLQVTGTLDTDTLEVMKKPRCGIPDINIGQFSTFGNNVKWQKNTLTYRIVN-YTPDMSQAEVQDSIQRALQVWASVTPLRFTRT-NSGPADIMVSFGRGAHGDYYPFDGPHGTLAHAFSPSSGIGGDVHFDDDETFTFRSSKGYVLFMVAAHEFGHSLGLSHSSDRGALMYPLYSFGYPD 245
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Match: coll (collagenase [Source:NCBI gene;Acc:100049293]) HSP 1 Score: 140.969 bits (354), Expect = 4.507e-37 Identity = 84/203 (41.38%), Postives = 113/203 (55.67%), Query Frame = 1 Query: 460 KEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKD--IQTRSMFG---KWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDG---RIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 +V+ + Q GL++TG LD ET + PRCGV D + S FG KW++ +L Y+ T ++ V E+I+ A WA VTPL FT+++ + ++ F + +H D +PFDG DGTLAHAF P G HFD DE FT GY L +VAAHE GH+LGL HS D ALM Y+ Y + +L DD Sbjct: 53 SQVTSKLIEMQTFFGLQITGTLDAETLAMMKKPRCGVSDSRVARFSTFGNNLKWEKNSLTYRITN-YTPDMSKEEVDESIEKALQVWARVTPLRFTKIY-SSTADIMVSFGQRAHGDYYPFDGPDGTLAHAFAPAPGIGGDAHFDDDETFTFRSNTGYVLFMVAAHEFGHSLGLSHSDDPGALMYPIYS-YRNPETFVLPRDD 252
BLAST of matrix metalloproteinase vs. Planmine SMEST
Match: SMESG000049445.1 (SMESG000049445.1) HSP 1 Score: 514.998 bits (1325), Expect = 6.692e-180 Identity = 263/264 (99.62%), Postives = 263/264 (99.62%), Query Frame = 1 Query: 262 MNPVFYRLIKWILIFGNXXXXXXXXXXXXXXXRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 1053 MNPVFY LIKWILIFGNVVSVSVAATTPSPSSRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK Sbjct: 1 MNPVFYGLIKWILIFGNVVSVSVAATTPSPSSRKLFGQMYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 264 HSP 2 Score: 59.6918 bits (143), Expect = 2.160e-9 Identity = 45/46 (97.83%), Postives = 46/46 (100.00%), Query Frame = 2 Query: 1049 KKIQQIYGRKPISSVTPRSEKSTKRRRMXXXXXXXXXXXXXXQDLV 1186 +KIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV Sbjct: 263 QKIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV 308
BLAST of matrix metalloproteinase vs. Planmine SMEST
Match: SMESG000049445.1 (SMESG000049445.1) HSP 1 Score: 478.019 bits (1229), Expect = 7.789e-166 Identity = 226/226 (100.00%), Postives = 226/226 (100.00%), Query Frame = 1 Query: 376 MYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 1053 MYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK Sbjct: 1 MYLVKYGYISIPEKVNQTGFGRSTLLDPKEVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTRSMFGKWKQKNLKYKFVGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHDDEFPFDGRDGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQK 226 HSP 2 Score: 59.6918 bits (143), Expect = 2.085e-9 Identity = 45/46 (97.83%), Postives = 46/46 (100.00%), Query Frame = 2 Query: 1049 KKIQQIYGRKPISSVTPRSEKSTKRRRMXXXXXXXXXXXXXXQDLV 1186 +KIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV Sbjct: 225 QKIQQIYGRKPISSVTPRSEKSTKRRRMTRLTTDSTTNPSTTQDLV 270
BLAST of matrix metalloproteinase vs. Planmine SMEST
Match: SMESG000014326.1 (SMESG000014326.1) HSP 1 Score: 122.094 bits (305), Expect = 3.072e-30 Identity = 80/219 (36.53%), Postives = 115/219 (52.51%), Query Frame = 1 Query: 463 EVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI-----QTRSMFGKWKQKNLKYKFV-----GPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHD------------DEFPFDGRDG-TLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 ++SD +K Q+ GL G + +E E RCG KD + + KW K Y+F P T +++ ++ A+ A NYW+ + F +V ++ + F L F+ H D +P D G LAHAFFP G +HFDS E +TEG++ G NLR+VAAHE+GHA+GL HS D +ALMA +Y GY ++ L +DD Q Sbjct: 44 KLSDAVKNIQKMAGLPTDGKITKELLAHVEKSRCGGKDSKKKSKRYNAAQSKW-DKGQTYRFYIHDERHPTT--MSLGEIQRALIIALNYWSTAADIYFGKVSSKQGSMFSLSFADAEHKMYDVHNNFAESRDPYPLDNVPGNVLAHAFFPKSGNLHFDSAEEWTEGKDDGINLRVVAAHEMGHAIGLYHSNDPKALMAPWYGGYISESDFRLPDDDSQ 259
BLAST of matrix metalloproteinase vs. Planmine SMEST
Match: SMESG000014326.1 (SMESG000014326.1) HSP 1 Score: 122.094 bits (305), Expect = 3.419e-30 Identity = 80/219 (36.53%), Postives = 115/219 (52.51%), Query Frame = 1 Query: 463 EVSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDI-----QTRSMFGKWKQKNLKYKFV-----GPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHD------------DEFPFDGRDG-TLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDDKQ 1050 ++SD +K Q+ GL G + +E E RCG KD + + KW K Y+F P T +++ ++ A+ A NYW+ + F +V ++ + F L F+ H D +P D G LAHAFFP G +HFDS E +TEG++ G NLR+VAAHE+GHA+GL HS D +ALMA +Y GY ++ L +DD Q Sbjct: 44 KLSDAVKNIQKMAGLPTDGKITKELLAHVEKSRCGGKDSKKKSKRYNAAQSKW-DKGQTYRFYIHDERHPTT--MSLGEIQRALIIALNYWSTAADIYFGKVSSKQGSMFSLSFADAEHKMYDVHNNFAESRDPYPLDNVPGNVLAHAFFPKSGNLHFDSAEEWTEGKDDGINLRVVAAHEMGHAIGLYHSNDPKALMAPWYGGYISESDFRLPDDDSQ 259
BLAST of matrix metalloproteinase vs. Planmine SMEST
Match: SMESG000040780.1 (SMESG000040780.1) HSP 1 Score: 120.553 bits (301), Expect = 1.154e-29 Identity = 74/214 (34.58%), Postives = 109/214 (50.93%), Query Frame = 1 Query: 466 VSDGIKLFQQKNGLKVTGILDEETRKKFELPRCGVKDIQTR-----SMFGKWKQKNLKYKF---VGPVTQYLTMSAVREAIQSAFNYWAEVTPLTFTEVFDEEKTNFILKFSRYSHD------------DEFPFDGR-DGTLAHAFFPTDGRIHFDSDEIFTEGEERGYNLRIVAAHEIGHALGLPHSYDSEALMASFYAGYTDKNMPLLNEDD 1044 + D +K Q+ G++ G L +E RCG KD + + KW + + YK+ + + + ++ + VR AIQ A +YW +V+ L F D+ F + F+ H+ D P D G LAH F+P +G +H+D+ E +TEG + G NLRIV AHE+GHA+GL HS D ALMA +Y GY + L DD Sbjct: 59 LKDSLKDLQKMAGIEADGKLSDEVISHMNKGRCGDKDKDKKSKRYVAHAKKW-DRGVTYKYYLHLDWMPRTMSEAEVRRAIQVALDYWVQVSNLGFAASRDKAGCMFSVSFAGRDHELYDVYNNFQSRKDHIPLDNVPSGVLAHGFYPKNGNLHYDNAETWTEGTDSGINLRIVTAHEMGHAIGLKHSNDPSALMAPWYGGYISEADYRLPNDD 271 The following BLAST results are available for this feature:
BLAST of matrix metalloproteinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of matrix metalloproteinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of matrix metalloproteinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of matrix metalloproteinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of matrix metalloproteinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025379 ID=SMED30025379|Name=matrix metalloproteinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1219bpback to top protein sequence of SMED30025379-orf-1 >SMED30025379-orf-1 ID=SMED30025379-orf-1|Name=SMED30025379-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=272bp MNPVFYRLIKWILIFGNVVSVSVAATTPSPSSRKLFGQMYLVKYGYISIPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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