Thioredoxin glutathione reductase

Query:   94 PPISTALEEWIRK----IINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDER-QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            P  S+   E +R+    +I  S ++IFSK+ CP   ++K+      ++   +E++ +  G+ +Q++L  ITNQ+TVPN+FV   H+GGCD   +A   G +QKLL E   Y+YDL++IGGGSGGL+ +KEAA  G KV VLDFV P+PQGT+WGLGGTCVNVGCIPKKLMHQ+ALL  +  D+R +GW   + V H+W+ M + IQNHI SLNWGYR SLR K V Y+N+YG F++ H IK T+K   E   T+  F+IATGERPRY  I GDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA  GL VTVMVRSI LRGFDQ+MA K+G YME+HGV F+ + +P  +  +E+GSPGK +V     +     +  +NTVL AIGRD CT +IGLE + + + +K+G++ VN+ EQ+ V  +YA+GDI+    +LTPVAIQ+GK L++RLFG      DY+NVPTTVFTPLEYG  GL+EE AI  Y KE++E++H  F PLEWTVA R +N CY K+ICNK D+ RV+GFH+L PNAGE+TQG+A AM+ G TK+  DDTIGIHPTC E FTTL ITK+SG D  Q GC G
Sbjct:   45 PSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG 643          

Query:   94 PPISTALEEWIRK----IINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDER-QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            P  S+   E +R+    +I  S ++IFSK+ CP   ++K+      ++   +E++ +  G+ +Q++L  ITNQ+TVPN+FV   H+GGCD   +A   G +QKLL E   Y+YDL++IGGGSGGL+ +KEAA  G KV VLDFV P+PQGT+WGLGGTCVNVGCIPKKLMHQ+ALL  +  D+R +GW   + V H+W+ M + IQNHI SLNWGYR SLR K V Y+N+YG F++ H IK T+K   E   T+  F+IATGERPRY  I GDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA  GL VTVMVRSI LRGFDQ+MA K+G YME+HGV F+ + +P  +  +E+GSPGK +V     +     +  +NTVL AIGRD CT +IGLE + + + +K+G++ VN+ EQ+ V  +YA+GDI+    +LTPVAIQ+GK L++RLFG      DY+NVPTTVFTPLEYG  GL+EE AI  Y KE++E++H  F PLEWTVA R +N CY K+ICNK D+ RV+GFH+L PNAGE+TQG+A AM+ G TK+  DDTIGIHPTC E FTTL ITK+SG D  Q GC G
Sbjct:   45 PSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG 643          

Query:  124 IRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD-------ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            ++  I+   ++IFS++TC  C ++KK  K   + Y  +E++    G  ++  L  +  +  +P VFV+   IGG     KA  EGR+QKLL         + Y+YDL++IGGGSGGLAA+KEAA +G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V ETV+H WD M+E +QNHI SLNWGYR +LR K V Y NAYG FI  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VP K+  +E G+PG+  V       +   +  +NTV+ AIGRD CT +IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   ++LTPVAIQAG+ L++RL+ G  +  DY NVPTTVFTPLEYG+ GL+EE A+ K+G+E+IEV+H  F PLEWT+  R +N CY K+ICN  DN RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SGA   Q+GC G
Sbjct:   59 LQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG 649          

Query:  124 IRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD-------ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            ++  I+   ++IFS++TC  C ++KK  K   + Y  +E++    G  ++  L  +  +  +P VFV+   IGG     KA  EGR+QKLL         + Y+YDL++IGGGSGGLAA+KEAA +G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V ETV+H WD M+E +QNHI SLNWGYR +LR K V Y NAYG FI  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VP K+  +E G+PG+  V       +   +  +NTV+ AIGRD CT +IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   ++LTPVAIQAG+ L++RL+ G  +  DY NVPTTVFTPLEYG+ GL+EE A+ K+G+E+IEV+H  F PLEWT+  R +N CY K+ICN  DN RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SGA   Q+GC
Sbjct:   59 LQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGC 647          

Query:  250 LATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD-------ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +  G  ++  L  +  +  +P VFV+   IGG     KA  EGR+QKLL         + Y+YDL++IGGGSGGLAA+KEAA +G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V ETV+H WD M+E +QNHI SLNWGYR +LR K V Y NAYG FI  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VP K+  +E G+PG+  V       +   +  +NTV+ AIGRD CT +IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   ++LTPVAIQAG+ L++RL+ G  +  DY NVPTTVFTPLEYG+ GL+EE A+ K+G+E+IEV+H  F PLEWT+  R +N CY K+ICN  DN RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SGA   Q+GC
Sbjct:    1 MEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGC 547          

Query:  112 LEEWIRKIINSSVLIIFS-----KTTCPFCYKIK--KSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPE-TVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGS---PGKKEVFGCYIKDKT----EYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDND-CYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQ-SGC*G 1872
            L+E +++  NS ++I ++     K    F   +   K   DA       EI  L      Q ++  +T   + P ++++G  +GG  +  KAL +  +++ L  R + YDL+VIGGGSGGLAA+KEA+  G KVA LDFVKP+PQGT+WGLGGTCVNVGCIPKKLMHQ++LL HS  DA+ YGW +PE  VEH W+++ + +Q+HI SLNWGYR  LR K V YIN+YG F     I  T+K      +T++ F+I+TG RP+YP IPG KEY ITSDDLF L Y PGKTL +GASYV+LECAGFL   G  VTVMVRSI LRGFDQ MA +I K+M  +G+ F    VPT+I  ++E +    GK  VF     ++T    E  + +NT+L AIGR+  TD +GL  + ++  K+ +V+   E+ +T+  +YAIGD++    +LTPVAIQAG+ L RR+F G + LT+Y  +PTTVFTPLEYG  GL+EEDA+ KYGK++I ++H  F PLE+T++ R D D CY K+IC +++  +VVGFH+L+PNAGE+TQG+ IA+++ A K DFD  IGIHPT +E FTTL + K  G +  Q SGC G
Sbjct:   35 LKEALKEAANSKIVIFYNSSDEEKQLVEFETYLNSLKEPADAEKPLEIPEIKKLQVSRASQKVIQYLTLHTSWPLMYIKGNAVGGLKEL-KALKQDYLKEWL--RDHTYDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQASLLGHSIHDAKKYGWKLPEGKVEHQWNHLRDSVQDHIASLNWGYRVQLREKTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYPEIPGVKEYTITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHMIAYGMKF-EAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGREAVTDDVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAENFTTLTLEKKEGDEELQASGCUG 634          

Query:  112 LEEWIRKIINSSVLIIFS-----KTTCPFCYKIK--KSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPE-TVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGS---PGKKEVFGCYIKDKT----EYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDND-CYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQ-SGC*G 1872
            L+E +++  NS ++I ++     K    F   +   K   DA       EI  L      Q ++  +T   + P ++++G  +GG  +  KAL +  +++ L  R + YDL+VIGGGSGGLAA+KEA+  G KVA LDFVKP+PQGT+WGLGGTCVNVGCIPKKLMHQ++LL HS  DA+ YGW +PE  VEH W+++ + +Q+HI SLNWGYR  LR K V YIN+YG F     I  T+K      +T++ F+I+TG RP+YP IPG KEY ITSDDLF L Y PGKTL +GASYV+LECAGFL   G  VTVMVRSI LRGFDQ MA +I K+M  +G+ F    VPT+I  ++E +    GK  VF     ++T    E  + +NT+L AIGR+  TD +GL  + ++  K+ +V+   E+ +T+  +YAIGD++    +LTPVAIQAG+ L RR+F G + LT+Y  +PTTVFTPLEYG  GL+EEDA+ KYGK++I ++H  F PLE+T++ R D D CY K+IC +++  +VVGFH+L+PNAGE+TQG+ IA+++ A K DFD  IGIHPT +E FTTL + K  G +  Q SGC G
Sbjct:   68 LKEALKEAANSKIVIFYNSSDEEKQLVEFETYLNSLKEPADAEKPLEIPEIKKLQVSRASQKVIQYLTLHTSWPLMYIKGNAVGGLKEL-KALKQDYLKEWL--RDHTYDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLMHQASLLGHSIHDAKKYGWKLPEGKVEHQWNHLRDSVQDHIASLNWGYRVQLREKTVTYINSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYPEIPGVKEYTITSDDLFQLPYSPGKTLCVGASYVSLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHMIAYGMKF-EAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGREAVTDDVGLTTIGVERAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFDGANELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDKDHCYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALKLAAKKADFDRLIGIHPTVAENFTTLTLEKKEGDEELQASGCUG 667          

Query:  412 EYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWN--VPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEH--TIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDK-NGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDND-CYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            ++DL+VIG GSGGL+ SK AA+ GA VA++D V+PTP G +WG+GGTC NVGCIPKKLMHQ+A++    + A  YGWN    E ++H W+ + + + + +++ NW YR  L  K ++Y NAY  F+D+    I  TDK   +  +++ N +I+TG RP+YPNIPG  E GITSDDLF+L+  PGKTL++G  YVALECAGFL++    V V+VRSI L+GFD+   + + ++++  GV  + E V  + +   E    KK+V         EY    +TV++A GR P    + L+N  +  DK +G+++ +E ++++ + +YA+GDI+    +LTP+AIQ+GK L+ RLF     +  +  V TTVFTPLE  ++GL EE+AI K+G++SIEVFH +F P E+ V    D+  CY K +C + ++ +++G H + PNA E+ QGYA+A R+G +  D  +TI IHP  SE F  L+ITK SG DP   GC G
Sbjct:   20 KFDLIVIGAGSGGLSCSKRAADLGANVALIDAVEPTPHGHSWGIGGTCANVGCIPKKLMHQAAIVGKELKHADKYGWNGIDQEKIKHDWNVLSKNVNDRVKANNWIYRVQLNQKKINYFNAYAEFVDKDKIVITGTDKNKTKNFLSAPNVVISTGLRPKYPNIPG-AELGITSDDLFTLASVPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRSIPLKGFDRDCVHFVMEHLKTTGVK-VKEHVEVERV---EAVGSKKKVTFTGNGGVEEY----DTVIWAAGRVPNLKSLNLDNAGVRTDKRSGKILADEFDRASCNGVYAVGDIVQDRQELTPLAIQSGKLLADRLFSNSKQIVRFDGVATTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTPFEYVVPQNKDSGFCYVKAVCTRDESQKILGLHFVGPNAAEVIQGYAVAFRVGISMSDLQNTIAIHPCSSEEFVKLHITKRSGQDPRTQGCCG 503          

Query:  412 EYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTD-KYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVR-SIFLRGFDQQMANKIGKYMEE--HGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE--HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            E+D +VIGGGSGG+A+++ A  FG  V +++         +  LGGTCVNVGC+PKK+M+  +L      D   YG++V    +  W  + +    +I+ LN  Y + L+   V+YI     F ++ T++    KY  +      N +IA G +P  PNI G  E+GI SD  F L   P +T+V+GA Y+A+E AG LA+LG    +++R    LR FD+ +++++   M+E  + +        T++I  ++G           IK  T   +   T+++AIGRDP T  + LE V +  DK+G +IV+E + ++   I ++GD   + L LTPVAI AG+ LS RLF GE  + LT Y N+ T VF+    G++GL E +A+ KYGK+ + ++   F P+ + V    +     KL+C   D  +VVG HV    + E+ QG+A+A+ MGATK+ FD T+ IHPT +E   T+
Sbjct:    6 EFDYLVIGGGSGGIASARRAREFGVSVGLIE---------SGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLN-KFDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAKYRGK------NTLIAVGGKPTIPNIKG-AEHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGL--------LTIKTTTGVIEKVQTLIWAIGRDPLTKELNLERVGVKTDKSGHIIVDEYQNTSAPGILSVGDDTGKFL-LTPVAIAAGRRLSHRLFNGETDNKLT-YENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAM-KLVCVGKDE-KVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTM 452          

Query:  412 EYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTD-KYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVR-SIFLRGFDQQMANKIGKYMEE--HGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE--HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            E+D +VIGGGSGG+A+++ A  FG  V +++         +  LGGTCVNVGC+PKK+M+  +L      D   YG++V    +  W  + +    +I+ LN  Y + L+   V+YI     F ++ T++    KY  +      N +IA G +P  PNI G  E+GI SD  F L   P +T+V+GA Y+A+E AG LA+LG    +++R    LR FD+ +++++   M+E  + +        T++I  ++G           IK  T   +   T+++AIGRDP T  + LE V +  DK+G +IV+E + ++   I ++GD   + L LTPVAI AG+ LS RLF GE  + LT Y N+ T VF+    G++GL E +A+ KYGK+ + ++   F P+ + V    +     KL+C   D  +VVG HV    + E+ QG+A+A+ MGATK+ FD T+ IHPT +E   T+
Sbjct:    6 EFDYLVIGGGSGGIASARRAREFGVSVGLIE---------SGRLGGTCVNVGCVPKKVMYNCSLHAEFIRDHADYGFDVTLN-KFDWKVIKKSRDEYIKRLNGLYESGLKGSSVEYIRGRATFAEDGTVEVNGAKYRGK------NTLIAVGGKPTIPNIKG-AEHGIDSDGFFDLEDLPSRTVVVGAGYIAVEIAGVLANLGSDTHLLIRYDKVLRTFDKMLSDELTADMDEETNPLHLHKNTQVTEVIKGDDGL--------LTIKTTTGVIEKVQTLIWAIGRDPLTKELNLERVGVKTDKSGHIIVDEYQNTSAPGILSVGDDTGKFL-LTPVAIAAGRRLSHRLFNGETDNKLT-YENIATVVFSHPLIGTVGLTEAEAVEKYGKDEVTLYKSRFNPMLFAVTKHKEKAAM-KLVCVGKDE-KVVGVHVFGVGSDEMLQGFAVAVTMGATKKQFDQTVAIHPTSAEELVTM 452          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQ-GTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            Y+YDL+VIGGGS GLA +KEA   GA+VA LDFVKPTP  GT WG+GGTCVNVGCIPKKLMHQ++LL  +  +A +YGWNV E ++  W  +V+ +QNHI+S+NW  R  LR+K V+YIN  G+F+D HT+    K + ER IT+  F+IA G RPRYP+IPG  EYGITSDDLFSL   PGKTLV+GA Y+ LECAGFL  LG + TVMVRSI LRGFDQQMA  +   MEE G+ F+ + VP   + +E+   GK  V    ++   E +D ++TVL+AIGR    D + L N  + + K+ ++ V+ +E + V+NIYA+GDII    +LTPVA+ AG+ L+RRL+GG     DY +V TTVFTPLEY  +GL+EEDA+ ++G + IEVFH  +KP E+ +  +    CY K +  +  + RV G H + P AGE+ QG+A A++ G T     +T+GIHPT +E FT L ITK SG DP  + C
Sbjct:    8 YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLK-SGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVP---LSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD-KIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 489          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQ-GTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            Y+YDL+VIGGGS GLA +KEA   GA+VA LDFVKPTP  GT WG+GGTCVNVGCIPKKLMHQ++LL  +  +A +YGWNV E ++  W  +V+ +QNHI+S+NW  R  LR+K V+YIN  G+F+D HT+    K + ER IT+  F+IA G RPRYP+IPG  EYGITSDDLFSL   PGKTLV+GA Y+ LECAGFL  LG + TVMVRSI LRGFDQQMA  +   MEE G+ F+ + VP   + +E+   GK  V    ++   E +D ++TVL+AIGR    D + L N  + + K+ ++ V+ +E + V+NIYA+GDII    +LTPVA+ AG+ L+RRL+GG     DY +V TTVFTPLEY  +GL+EEDA+ ++G + IEVFH  +KP E+ +  +    CY K +  +  + RV G H + P AGE+ QG+A A++ G T     +T+GIHPT +E FT L ITK SG DP  + C
Sbjct:   25 YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLK-SGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVP---LSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD-KIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 506          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQ-GTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            Y+YDL+VIGGGS GLA +KEA   GA+VA LDFVKPTP  GT WG+GGTCVNVGCIPKKLMHQ++LL  +  +A +YGWNV E ++  W  +V+ +QNHI+S+NW  R  LR+K V+YIN  G+F+D HT+    K + ER IT+  F+IA G RPRYP+IPG  EYGITSDDLFSL   PGKTLV+GA Y+ LECAGFL  LG + TVMVRSI LRGFDQQMA  +   MEE G+ F+ + VP   + +E+   GK  V    ++   E +D ++TVL+AIGR    D + L N  + + K+ ++ V+ +E + V+NIYA+GDII    +LTPVA+ AG+ L+RRL+GG     DY +V TTVFTPLEY  +GL+EEDA+ ++G + IEVFH  +KP E+ +  +    CY K +  +  + RV G H + P AGE+ QG+A A++ G T     +T+GIHPT +E FT L ITK SG DP  + C
Sbjct:  113 YDYDLIVIGGGSAGLACAKEAVLNGARVACLDFVKPTPTLGTKWGVGGTCVNVGCIPKKLMHQASLLGEAVHEAAAYGWNVDEKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGLGSFVDSHTLLAKLK-SGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIPFLRKTVP---LSVEKQDDGKLLVKYKNVETGEEAEDVYDTVLWAIGRKGLVDDLNLPNAGVTVQKD-KIPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLARRLYGGSTQRMDYKDVATTVFTPLEYACVGLSEEDAVKQFGADEIEVFHGYYKPTEFFIPQKSVRYCYLKAVAERHGDQRVYGLHYIGPVAGEVIQGFAAALKSGLTINTLINTVGIHPTTAEEFTRLAITKRSGLDPTPASC 594          

Query:  406 QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPET-VEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNE-RIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +Y+YDLVV+GGGS GLA +KEAA  GA+V   D+VKPTP GT WG+GGTCVNVGCIPKKLMHQ++LL  +  +A +YGWNV +T +   W  +V  +QNHI+S+NW  R  LR+K V+Y+N+   F D HTI+       E R +TS   ++A G RPRYP+IPG  E GITSDD+FS    PG+TLV+GA YV LECA FL  LG + TVMVRSI LRGFD+QM+  +   M E G+ F+   +P  +   E  + G+  V       + +  D F+TVL+AIGR    + + L+   +    + +++V+  E ++V +I+A+GDII    +LTPVAI +G+ L+RRLF G   L DY +V TTVFTPLEY  +G++EE AI   G ++IEVFH  +KP E+ +  +    CY K +   S + +++G H + P AGE+ QG+A A++ G T +   +T+GIHPT +E FT L+ITK SG DP  + C
Sbjct:   30 RYDYDLVVLGGGSAGLACAKEAAGCGARVLCFDYVKPTPVGTKWGIGGTCVNVGCIPKKLMHQASLLGEAVHEAVAYGWNVDDTNIRPDWRKLVRSVQNHIKSVNWVTRVDLRDKKVEYVNSMATFRDSHTIEYVAMPGAEHRQVTSEYVVVAVGGRPRYPDIPGAVELGITSDDIFSYEREPGRTLVVGAGYVGLECACFLKGLGYEPTVMVRSIVLRGFDRQMSELLAAMMTERGIPFLGTTIPKAV---ERQADGRLLVRYRNTTTQMDGSDVFDTVLWAIGRKGLIEDLNLDAAGVKTHDD-KIVVDAAEATSVPHIFAVGDIIYGRPELTPVAILSGRLLARRLFAGSTQLMDYADVATTVFTPLEYSCVGMSEETAIELRGADNIEVFHGYYKPTEFFIPQKSVRHCYLKAVAEVSGDQKILGLHYIGPVAGEVIQGFAAALKTGLTVKTLLNTVGIHPTTAEEFTRLSITKRSGRDPTPASC 514          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCE--DARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATG-ERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM--VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKI-----------IPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAH-RGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASG 1842
            +E D+VVIG G GG  A+ +AA  G K   ++            LGGTC+NVGCIP K +  ++   H     D    G +   +V    + ++ +  N +++L  G     +   V  +  +G  ++ + ++      +   + + N +IATG E   +P I  D+E  ++S     L+  P   +VIGA  + LE     + LG +VT +  + +I   G D +++    K + + G+ F    + TK+           + +E    G+KE   C            + +L ++GR P T+ +GLE V I  D  GR+ VN   Q+ V NIYAIGD I  G  L   A   G      + GG H+  DY  VP+ V+T  E   +G +EE    +  +E +      F  L  + A    D D + K++ +++ + +++G H++ P AGE+     +AM  GA   D       HPTCSE     N+  A G
Sbjct:   36 HEADIVVIGSGPGGYVAAIKAAQMGMKTVSVE--------KEATLGGTCLNVGCIPSKALLNNSHYYHMAHSGDLEKRGISCG-SVSLDLEKLMGQKSNAVKALTGGIAMLFKKNKVTQLTGFGTIVNPNEVEVKKSDGSTETVKTKNILIATGSEVTPFPGIEIDEEVIVSSTGALKLAKVPKHLVVIGAGVIGLELGSVWSRLGAEVTAIEFMDTIGGVGIDNEVSKTFQKVLTKQGLKF---KLGTKVTAASRSGDNVTVSVENAKSGEKEEIQC------------DALLVSVGRRPYTEGLGLEAVGIVKDDRGRIPVNATFQTVVPNIYAIGDCI-HGPMLAHKAEDEGLITIEGINGG-HVHIDYNCVPSVVYTHPEVAWVGKSEE----QLKQEGVAYKVGKFPFLANSRAKTNNDTDGFVKVLADQATD-KILGTHIIGPGAGELINEAVLAMEYGAAAEDVARVCHAHPTCSEALREANVAAAFG 499          

Query:   91 MPPIST-----ALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDE--RQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPPI        +   I+++I+SS +++FSK+ CPFC K+K   K+ N+KY  +E++L+  G+  QD+L+ +T Q+TVPNVF+   HIGGCD+  KA  +G +QKLL E    Y+YDL+VIGGGSGGLA SKEAA  G KV VLD+V PTPQGT WGLGGTCVNVGCIPKKLMHQ+ALL  + EDAR +GW   E V H+W+ M   + N+I SLNWGYR SLR+K V+Y+NAY  F++ H IK T+K   E   T+  F++ATGERPRY  IPGDKE+ ITSDDLFSL YCPGKTLV+GASYVALEC GFLA LGL VT+MVRSI LRGFDQ MA++ G+YME HGV F+ + VPTKI  +E G+PG+ +V     + +  ++  +NTVL A+GRD CT +IGL+   + + +KNG+V VN+EEQ+ V +IYAIGDI+    +LTPVAIQAGK L+RRL+ G  +  DYVNVPTTVFTP+EYGS G  EE AI  YG+E++EV+H  F PLE+TV  R +N CY K+ICNK DN+RV+GFH L PNAGE+TQG+  AM+ G TK   D+TIGIHPTC+E FTT+ +TK+SG D  QSGC
Sbjct:    1 MPPIENDAGREQIRSKIKELIDSSAVVVFSKSFCPFCVKVKDLFKELNVKYNTIELDLMEDGTNYQDLLHEMTGQKTVPNVFINKKHIGGCDNTMKAHKDGVLQKLLGEGSEVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKKLMHQTALLGTAMEDARKFGWEFAEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKFLRKFVPTKIEQLEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPGRDNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGDITQSGC 600          

Query:   91 MPPIST-----ALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDE--RQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            MPPI        +   I+++I+SS +++FSK+ CPFC K+K   K+ N+KY  +E++L+  G+  QD+L+ +T Q+TVPNVF+   HIGGCD+  KA  +G +QKLL E    Y+YDL+VIGGGSGGLA SKEAA  G KV VLD+V PTPQGT WGLGGTCVNVGCIPKKLMHQ+ALL  + EDAR +GW   E V H+W+ M   + N+I SLNWGYR SLR+K V+Y+NAY  F++ H IK T+K   E   T+  F++ATGERPRY  IPGDKE+ ITSDDLFSL YCPGKTLV+GASYVALEC GFLA LGL VT+MVRSI LRGFDQ MA++ G+YME HGV F+ + VPTKI  +E G+PG+ +V     + +  ++  +NTVL A+GRD CT +IGL+   + + +KNG+V VN+EEQ+ V +IYAIGDI+    +LTPVAIQAGK L+RRL+ G  +  DYVNVPTTVFTP+EYGS G  EE AI  YG+E++EV+H  F PLE+TV  R +N CY K+ICNK DN+RV+GFH L PNAGE+TQG+  AM+ G TK   D+TIGIHPTC+E FTT+ +TK+SG D  QSGC G
Sbjct:    1 MPPIENDAGREQIRSKIKELIDSSAVVVFSKSFCPFCVKVKDLFKELNVKYNTIELDLMEDGTNYQDLLHEMTGQKTVPNVFINKKHIGGCDNTMKAHKDGVLQKLLGEGSEVYDYDLIVIGGGSGGLACSKEAATLGKKVMVLDYVVPTPQGTAWGLGGTCVNVGCIPKKLMHQTALLGTAMEDARKFGWEFAEQVTHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNAYAEFVEPHKIKATNKRGKETFYTAAQFVLATGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMADRAGEYMETHGVKFLRKFVPTKIEQLEAGTPGRIKVTAKSTESEEVFEGEYNTVLIAVGRDACTGKIGLDKAGVKINEKNGKVPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGATMKCDYVNVPTTVFTPMEYGSCGHPEEKAIQMYGQENLEVYHSLFWPLEFTVPGRDNNKCYAKIICNKLDNLRVIGFHYLGPNAGEVTQGFGAAMKCGITKDQLDNTIGIHPTCAEIFTTMEVTKSSGGDITQSGCUG 602          

Query:  406 QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDK-NGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +++YDLVVIGGGSGGLA SKEAA  G KVAVLD+V+P+ +GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +DAR YGW +PET+ H W  M E +QNH++SLNWG+R  L++K V Y+N  G  +D+HT++  +    E  +T+ N ++ATG RP+YP ++PG  E+GITSDD+F L   P KTL+IGASYV+LECAGFL  +GL  +VMVRSI LRGFDQQM+  +  YME +G  F  +C P  +   E+   G  +V    +  K E++D FN+VL+A+GR P T  + LE V + ++K  G++IV  +E ++V NI+AIGDI     +LTP AI+AGK L+ RL G    L +Y NV TTVFTPLEYG +GL+EE+A  ++GK+ IEV+H  +KPLE+TVA R    CY K++C +  + RV+G H   PNAGE+TQG+A+  + G T     +T+GIHPTC+E  T LNITK SG D   +GC
Sbjct:   30 KFDYDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPSLKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDARKYGWQIPETLSHDWPTMAEAVQNHVRSLNWGHRVQLQDKKVKYLNMKGTLLDKHTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGITSDDIFWLKESPKKTLIIGASYVSLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDYMETYGTKFHWKCTPKSV---EKLPSGHLQVTWMDLNTKEEHQDTFNSVLWAVGRAPETKTLNLEKVGVKINKETGKIIVAADEATSVPNIFAIGDIGEGRPELTPTAIKAGKLLAHRLAGRSTELMNYENVATTVFTPLEYGCVGLSEEEAERRHGKDQIEVYHAFYKPLEFTVAERDATQCYIKVVCLREGDQRVLGLHFTGPNAGEVTQGFALGFQCGLTYEHLRNTVGIHPTCAEELTKLNITKRSGLDATVTGC 515          

Query:  406 QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAI 1251
            +++YDLVVIGGGSGGLA SKEAA  G KVAVLD+V+P+ +GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +DAR YGW +PET+ H W  M E +QNH++SLNWG+R  L++K V Y+N  G  +D+HT++  +    E  +T+ N ++ATG RP+YP ++PG  E+GITSDD+F L   P KTL+IGASYV+LECAGFL  +GL  +VMVRSI LRGFDQQM+  +  YME +G  F  +C P  +   E+   G  +V    +  K E++D FN+VL+A+
Sbjct:   30 KFDYDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVEPSLKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDARKYGWQIPETLSHDWPTMAEAVQNHVRSLNWGHRVQLQDKKVKYLNMKGTLLDKHTVRAVNAQGKEMTVTARNILLATGGRPKYPTHVPGAMEFGITSDDIFWLKESPKKTLIIGASYVSLECAGFLTGIGLDTSVMVRSIALRGFDQQMSGLVTDYMETYGTKFHWKCTPKSV---EKLPSGHLQVTWMDLNTKEEHQDTFNSVLWAV 309          

Query:  463 KEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFID--EHTIKTTDKYNNERIITSNNFIIATGERPRY---PNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSI-FLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTV------LFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE-HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            + AA  GA  AV++         +  LGGTCVNVGC+PKK+M  ++       D   YG+   +    SW  +  +   ++  LN  YR++L    +++I+ Y  F D  E T++      N +  T+ + +I+TG  P      ++PG    GITSD  F L  CP +++++GA Y+A+E AG L++LG K ++++R    LR FD  +++   K ++ +G+D       T++  +++   G          D  + ++ F+T+      L+AIGR+P T  + L  + + LD+ G ++V+E + ++   +YA+GD+  R L LTPVAI AG+ L+ RLF G+     DY N+PT VF+    G++GL E++A+  YGK+ ++V+  +F P+ + +  R  + C  KL+C   +N +VVG H+      E+ QG+A+A+ MGATK DFD TI IHPT SE   TL
Sbjct:   56 RRAAELGATTAVIE---------SHRLGGTCVNVGCVPKKVMWNTSTHAEYLHDHEDYGFEGAK-AHFSWQIIKHKRDAYVSRLNQIYRSNLEKGKIEFIHGYARFTDDPEPTVEV-----NGKKYTATHILISTGGHPSTVSEDDVPGS-SLGITSDGFFELESCPKRSVIVGAGYIAVEMAGILSTLGSKTSIIIRQGGVLRNFDALISSNCTKELQNNGIDLRKN---TQVKSVKKNGKGLSITLVTKDPDDKDSQEKFDTINDVDCLLWAIGREPNTAGLNLSQIGVKLDERGHIVVDEFQNTSRPGVYAVGDVCGRAL-LTPVAIAAGRKLAHRLFEGKADSKVDYNNIPTVVFSHPPIGTVGLTEDEAVKTYGKDKVKVYTTSFTPMYYAITTR-KSQCIMKLVC-AGENEKVVGLHMQGFGCDEMLQGFAVAVNMGATKADFDRTIAIHPTSSEELVTL 499          

Query:   91 MPPISTAL-EEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP    L +  ++++I+S+ +++FSK+ CP+C ++K+       +Y A+E++    G+ IQ+ L+ +T QRTVPNVFV  TH+GGCD   KA  +G + KLL +    Y+YDL+VIGGGSGGLA SKEAA+FG KV VLD+V PTP+GT+WGLGGTCVNVGCIPKKLMHQ+A+L  S +D+R +GW   E V+H+WD M E IQN+I SLNWGYR SLR+K V Y NAYG F++ H IK T+K   E   T+  F++ATGERPRY NIPGDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL  TVMVRSI LRGFDQ+MAN+ G YME HGV FI + VP  +  +EEG+PG+ +V     +     +D +NTVL A+GRD CT  IGLE + + + ++NG++ V++EEQ++V  +YAIGDI+   L+LTPVAIQAG+ L+RRL+ G  +  DYVNVPTTVFTPLEYG  G AEE AI  YG+E++EV+H  F PLEWTV  R +N C+ K+ICNK D+ RVVGFHVL PNAGEITQG+  A++ G TK   D+TIGIHPTC+E FTT++++K+SG D  Q GC
Sbjct:   34 MPPTGRELLQARVKELIDSNRVMVFSKSFCPYCDQVKELFSSLGAEYQALELDECDDGTAIQETLHELTGQRTVPNVFVNKTHVGGCDKTLKAHKDGSLAKLLGDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLMHQAAILGQSLKDSRKFGWEYEEQVKHNWDTMREAIQNYIGSLNWGYRVSLRDKQVRYENAYGEFVEPHKIKATNKRGKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDATVMVRSILLRGFDQEMANRAGAYMETHGVKFIKQFVPISVELLEEGTPGRLKVTAKATEGDQIIEDEYNTVLIAVGRDACTRNIGLEKIGVKVNERNGKIPVSDEEQTSVPYVYAIGDILDGKLELTPVAIQAGRLLARRLYKGSKLKCDYVNVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTVPSRDNNTCFAKIICNKQDDDRVVGFHVLGPNAGEITQGFGAAIKCGLTKEKLDETIGIHPTCAEVFTTMDVSKSSGGDITQKGC 629          

Query:   91 MPPISTAL-EEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP    L +  ++++I+S+ +++FSK+ CP+C ++ +S           E      G+ IQ+ L+ +T QRTVPNVFV  TH+GGCD   KA  +G + KLL +    Y+YDL+VIGGGSGGLA SKEAA+FG KV VLD+V PTP+GT+WGLGGTCVNVGCIPKKLMHQ+A+L  S +D+R +GW   E V+H+WD M E IQN+I SLNWGYR SLR+K V Y NAYG F++ H IK T+K   E   T+  F++ATGERPRY NIPGDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL  TVMVRSI LRGFDQ+MAN+ G YME HGV FI + VP  +  +EEG+PG+ +V     +     +D +NTVL A+GRD CT  IGLE + + + ++NG++ V++EEQ++V  +YAIGDI+   L+LTPVAIQAG+ L+RRL+ G  +  DYVNVPTTVFTPLEYG  G AEE AI  YG+E++EV+H  F PLEWTV  R +N C+ K+ICNK D+ RVVGFHVL PNAGEITQG+  A++ G TK   D+TIGIHPTC+E FTT++++K+SG D  Q GC
Sbjct:    1 MPPTGRELLQARVKELIDSNRVMVFSKSFCPYCDQVSESA-------PCWEAGACYDGTAIQETLHELTGQRTVPNVFVNKTHVGGCDKTLKAHKDGSLAKLLGDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLMHQAAILGQSLKDSRKFGWEYEEQVKHNWDTMREAIQNYIGSLNWGYRVSLRDKQVRYENAYGEFVEPHKIKATNKRGKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDATVMVRSILLRGFDQEMANRAGAYMETHGVKFIKQFVPISVELLEEGTPGRLKVTAKATEGDQIIEDEYNTVLIAVGRDACTRNIGLEKIGVKVNERNGKIPVSDEEQTSVPYVYAIGDILDGKLELTPVAIQAGRLLARRLYKGSKLKCDYVNVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTVPSRDNNTCFAKIICNKQDDDRVVGFHVLGPNAGEITQGFGAAIKCGLTKEKLDETIGIHPTCAEVFTTMDVSKSSGGDITQKGC 589          

Query:   91 MPPISTAL-EEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSE 1806
            MPP    L +  ++++I+S+ +++FSK+ CP+C ++K+       +Y A+E++    G+ IQ+ L+ +T QRTVPNVFV  TH+GGCD   KA  +G + KLL +    Y+YDL+VIGGGSGGLA SKEAA+FG KV VLD+V PTP+GT+WGLGGTCVNVGCIPKKLMHQ+A+L  S +D+R +GW   E V+H+WD M E IQN+I SLNWGYR SLR+K V Y NAYG F++ H IK T+K   E   T+  F++ATGERPRY NIPGDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL  TVMVRSI LRGFDQ+MAN+ G YME HGV FI + VP  +  +EEG+PG+ +V     +     +D +NTVL A+GRD CT  IGLE + + + ++NG++ V++EEQ++V  +YAIGDI+   L+LTPVAIQAG+ L+RRL+ G  +  DYVNVPTTVFTPLEYG  G AEE AI  YG+E++EV+H  F PLEWTV  R +N C+ K+ICNK D+ RVVGFHVL PNAGEITQG+  A++ G TK   D+TIGIHPTC+E
Sbjct:    1 MPPTGRELLQARVKELIDSNRVMVFSKSFCPYCDQVKELFSSLGAEYQALELDECDDGTAIQETLHELTGQRTVPNVFVNKTHVGGCDKTLKAHKDGSLAKLLGDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLMHQAAILGQSLKDSRKFGWEYEEQVKHNWDTMREAIQNYIGSLNWGYRVSLRDKQVRYENAYGEFVEPHKIKATNKRGKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDATVMVRSILLRGFDQEMANRAGAYMETHGVKFIKQFVPISVELLEEGTPGRLKVTAKATEGDQIIEDEYNTVLIAVGRDACTRNIGLEKIGVKVNERNGKIPVSDEEQTSVPYVYAIGDILDGKLELTPVAIQAGRLLARRLYKGSKLKCDYVNVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTVPSRDNNTCFAKIICNKQDDDRVVGFHVLGPNAGEITQGFGAAIKCGLTKEKLDETIGIHPTCAE 576          

Query:  154 IIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            ++FSK+ CP+C ++K+       +Y A+E++    G+ IQ+ L+ +T QRTVPNVFV  TH+GGCD   KA  +G + KLL +    Y+YDL+VIGGGSGGLA SKEAA+FG KV VLD+V PTP+GT+WGLGGTCVNVGCIPKKLMHQ+A+L  S +D+R +GW   E V+H+WD M E IQN+I SLNWGYR SLR+K V Y NAYG F++ H IK + +   E   T+  F++ATGERPRY NIPGDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL  TVMVRSI LRGFDQ+MAN+ G YME HGV FI + VP                                +VL A+GRD CT  IGLE + + + ++NG++ V++EEQ++V  +YAIGDI+   L+LTPVAIQAG+ L+RRL+ G  +  DYVNVPTTVFTPLEYG  G AEE AI  YG+E++EV+H  F PLEWTV  R +N C+ K+ICNK D+ RVVGFHVL PNAGEITQG+  A++ G TK   D+TIGIHPTC+E FTT++++K+SG D  Q GC
Sbjct:    1 MVFSKSFCPYCDQVKELFSSLGAEYQALELDECDDGTAIQETLHELTGQRTVPNVFVNKTHVGGCDKTLKAHKDGSLAKLLGDNSVTYDYDLIVIGGGSGGLACSKEAASFGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLMHQAAILGQSLKDSRKFGWEYEEQVKHNWDTMREAIQNYIGSLNWGYRVSLRDKQVRYENAYGEFVEPHKIKVSGR-GKESFFTAEKFVVATGERPRYLNIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDATVMVRSILLRGFDQEMANRAGAYMETHGVKFIKQFVPI-------------------------------SVLIAVGRDACTRNIGLEKIGVKVNERNGKIPVSDEEQTSVPYVYAIGDILDGKLELTPVAIQAGRLLARRLYKGSKLKCDYVNVPTTVFTPLEYGCCGYAEEKAIEIYGEENLEVYHTLFWPLEWTVPSRDNNTCFAKIICNKQDDDRVVGFHVLGPNAGEITQGFGAAIKCGLTKEKLDETIGIHPTCAEVFTTMDVSKSSGGDITQKGC 542          

Query:  106 TALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ-------YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLE--NVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            + L+  I + I SS ++IFSKT+C  C   K+SL D               G +++++LY  T + ++P+VFV+  HIG  DD  K   E   QKLL+ ++       Y+YDL+VIGGGSGGLAASKEAAN+G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL+ + +D++ YGW + + ++H+W+ M + + N+I SLN+ YR SL    V Y N YG F++ HTIK+T+    E+  T+  F+IATGERPRY  IPGDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL VTVMVRSI LRGFDQQMAN IG+YMEEHGV FI +CVPTKI  +E G+PG+ +V      D  E  + +NTVL AIGRD CT  IGLE   VKI+ +K G++ VN+EEQ+ V  IYAIGD++   L+LTPVAIQAG+ L+RRL+G   +  DYVNVPTTVFTPLEYG+ GL+EE AI +Y +E+IEV+H  F PLEWTV  R +N CY K+ICN  D  RVVGFHVLSPNAGEITQG+A+A++ G TK   D+TIGIHP C+E FTTL +TK SG +  QSGC
Sbjct:    7 SGLKIEIEEYICSSDVVIFSKTSCNSC--AKRSLFD-----------FTENGHKLEELLYEQTMETSLPSVFVKEKHIGNYDDILKLSKENLFQKLLETKEDNPDRSGYDYDLIVIGGGSGGLAASKEAANYGKKVLVLDFVTPTPLGTKWGLGGTCVNVGCIPKKLMHQAALLRQALKDSQKYGWQIEDNIQHNWEIMTDSVLNYIGSLNFNYRVSLMQNNVKYENGYGEFVEPHTIKSTNSRGKEKYFTAEKFLIATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMANMIGEYMEEHGVKFIKQCVPTKIEQIEAGTPGRLKVTS-QASDGAETTEEYNTVLLAIGRDACTRNIGLEIPGVKIN-EKTGKIPVNDEEQTNVPYIYAIGDVLQDKLELTPVAIQAGRLLARRLYGDSTVKCDYVNVPTTVFTPLEYGACGLSEEHAIRQYEEENIEVYHSYFWPLEWTVPARDNNKCYAKIICNLKDKGRVVGFHVLSPNAGEITQGFAVAIKCGLTKDQLDNTIGIHPVCAEIFTTLTVTKRSGGNILQSGC 587          

Query:  133 IINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL-DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            +I  + ++IFSK+ CP   ++K+      + Y  +E++ +  G+ +Q++L  I+NQ+TVPN+FV   H+GGCD   +A   G +QKLL D+  ++YDL++IGGGSGGL+ +KEAAN G KV VLDFV P+PQGTTWGLGGTCVNVGCIPKKLMHQ+ALL H+ +DA+ YGW   + V+H+W+ M E IQ+HI SLNWGYR +LR KGV Y+N++G F+D H IK T+K   E   T++ F+IATGERPRY  I GDKEY ITSDDLFSL YCPG TLV+GASYV LECAGFLA LGL VTVMVRS+ LRGFDQ+MA K+G Y+E+ GV F  +  P  +  +E+G PGK +V     +     +  +NTVL AIGRD CT +IGLE + + + +KNG++ VN+ EQ+ V ++YAIGDI+    +LTPVAIQAGK L+RRLFG      DY+N+PTTVFTPLEYG  GL+EE AI  Y KE++EV+H  F PLEWTVA R +N CY K+ICNK DN RVVGFH+L PNAGEITQG+A AM+ G TK+  DDTIGIHPTC E FTTL ITK+SG D  Q GC G
Sbjct:   34 LIEGNRVMIFSKSYCPHSTRVKELFSSLGVVYNILELDQVDDGASVQEVLTEISNQKTVPNIFVNKVHVGGCDRTFQAHQNGLLQKLLQDDSAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKKLMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTYVNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVKFQRKFTPILVQQLEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG 615          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            Y++DL++IGGGSGGLAA+KEAA F  KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V +TV+H W+ M E +Q+HI SLNWGYR +LR K V Y NAYG FI  H I  T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VPTKI  +E G+PG+  V       +   +  FNTVL A+GRD CT  IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   L+LTPVAIQAG+ L++RL+GG ++  DY NVPTTVFTPLEYG  GL+EE A+ K+G+E+IEV+H  F PLEWTV  R +N CY K+ICN  D+ RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SG D  QSGC G
Sbjct:   11 YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG 499          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            Y++DL++IGGGSGGLAA+KEAA F  KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V +TV+H W+ M E +Q+HI SLNWGYR +LR K V Y NAYG FI  H I  T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VPTKI  +E G+PG+  V       +   +  FNTVL A+GRD CT  IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   L+LTPVAIQAG+ L++RL+GG ++  DY NVPTTVFTPLEYG  GL+EE A+ K+G+E+IEV+H  F PLEWTV  R +N CY K+ICN  D+ RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SG D  QSGC G
Sbjct:   11 YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG 499          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            Y++DL++IGGGSGGLAA+KEAA F  KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V +TV+H W+ M E +Q+HI SLNWGYR +LR K V Y NAYG FI  H I  T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VPTKI  +E G+PG+  V       +   +  FNTVL A+GRD CT  IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   L+LTPVAIQAG+ L++RL+GG ++  DY NVPTTVFTPLEYG  GL+EE A+ K+G+E+IEV+H  F PLEWTV  R +N CY K+ICN  D+ RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SG D  QSGC G
Sbjct:   11 YDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG 499          

Query:  373 EGRIQKLLDER-------QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            +G++QKL            Y++DL++IGGGSGGLAA+KEAA F  KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V +TV+H W+ M E +Q+HI SLNWGYR +LR K V Y NAYG FI  H I  T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VPTKI  +E G+PG+  V       +   +  FNTVL A+GRD CT  IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   L+LTPVAIQAG+ L++RL+GG ++  DY NVPTTVFTPLEYG  GL+EE A+ K+G+E+IEV+H  F PLEWTV  R +N CY K+ICN  D+ RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SG D  QSGC G
Sbjct:  106 KGQLQKLPTMNGSKDPPGSYDFDLIIIGGGSGGLAAAKEAAKFDKKVLVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALKDSRNYGWKVEDTVKHDWEKMTESVQSHIGSLNWGYRVALREKKVVYENAYGRFIGPHRIVATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLRVTAQSTNSEETIEGEFNTVLLAVGRDSCTRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSNVKCDYDNVPTTVFTPLEYGCCGLSEEKAVEKFGEENIEVYHSFFWPLEWTVPSRDNNKCYAKIICNLKDDERVVGFHVLGPNAGEVTQGFAAALKCGLTKQQLDSTIGIHPVCAEIFTTLSVTKRSGGDILQSGCUG 613          

Query:   94 PPISTALEEWIRK----IINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDER-QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            P  S+   E +R+    +I  S ++IFSK+ CP   ++K+      ++   +E++ +  G+ +Q++L  ITNQ+TVPN+FV   H+GGCD   +A   G +QKLL E   Y+YDL++IGGGSGGL+ +KEAA  G KV VLDFV P+PQGT+WGLGGTCVNVGCIPKKLMHQ+ALL  +  D+R +GW   + V H+W+ M + IQNHI SLNWGYR SLR K V Y+N+YG F++ H IK T+K   E   T+  F+IATGERPRY  I GDKEY ITSDDLFSL YCPGKTLV+GASYVALECAGFLA  GL VTVMVRSI LRGFDQ+MA K+G YME+HGV F+ + +P  +  +E+GSPGK +V     +     +  +NTVL AIGRD CT +IGLE + + + +K+G++ VN+ EQ+ V  +YA+GDI+    +LTPVAIQ+GK L++RLFG      DY+NVPTTVFTPLEYG  GL+EE AI  Y KE++E++H  F PLEWTVA R +N CY K+ICNK D+ RV+GFH+L PNAGE+TQG+A AM+ G TK+  DDTIGIHPTC E FTTL ITK+SG D  Q GC G
Sbjct:   45 PSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHSTRVKELFSSLGVECNVLELDQVDDGARVQEVLSEITNQKTVPNIFVNKVHVGGCDQTFQAYQSGLLQKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKLKVLAKSTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKSGKIPVNDVEQTNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCCGLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTCYAKIICNKFDHDRVIGFHILGPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG 643          

Query:  133 IINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL-DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            +I  + ++IFSK+ CP   ++K+      + Y  +E++ +  G+ +Q++L  I+NQ+TVPN+FV   H+GGCD   +A   G +QKLL D+  ++YDL++IGGGSGGL+ +KEAAN G KV VLDFV P+PQGTTWGLGGTCVNVGCIPKKLMHQ+ALL H+ +DA+ YGW   + V+H+W+ M E IQ+HI SLNWGYR +LR KGV Y+N++G F+D H IK T+K   E   T++ F+IATGERPRY  I GDKEY ITSDDLFSL YCPG TLV+GASYV LECAGFLA LGL VTVMVRS+ LRGFDQ+MA K+G Y+E+ GV F  +  P  +  +E+G PGK +V     +     +  +NTVL AIGRD CT +IGLE + + + +KNG++ VN+ EQ+ V ++YAIGDI+    +LTPVAIQAGK L+RRLFG      DY+N+PTTVFTPLEYG  GL+EE AI  Y KE++EV+H  F PLEWTVA R +N CY K+ICNK DN RVVGFH+L PNAGEITQG+A AM+ G TK+  DDTIGIHPTC E FTTL ITK+SG D  Q GC G
Sbjct:   71 LIEGNRVMIFSKSYCPHSTRVKELFSSLGVVYNILELDQVDDGASVQEVLTEISNQKTVPNIFVNKVHVGGCDRTFQAHQNGLLQKLLQDDSAHDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKKLMHQAALLGHALQDAKKYGWEYNQQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTYVNSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLPYCPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVKFQRKFTPILVQQLEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVKINEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKCDYINIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKIICNKFDNERVVGFHLLGPNAGEITQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDITQKGCUG 652          

Query:  124 IRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD-------ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            ++  I+   ++IFS++TC  C ++KK  K   + Y  +E++    G  ++  L  +  +  +P VFV+   IGG     KA  EGR+QKLL         + Y+YDL++IGGGSGGLAA+KEAA +G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V ETV+H WD M+E +QNHI SLNWGYR +LR K V Y NAYG FI  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VP K+  +E G+PG+  V       +   +  +NTV+ AIGRD CT +IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   ++LTPVAIQAG+ L++RL+ G  +  DY NVPTTVFTPLEYG+ GL+EE A+ K+G+E+IEV+H  F PLEWT+  R +N CY K+ICN  DN RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SGA   Q+GC G
Sbjct:   59 LQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG 649          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            Y+YDL++IGGGSGGLAA+KEAA +G KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +D+R+YGW V ETV+H WD M+E +QNHI SLNWGYR +LR K V Y NAYG FI  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTL++GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++MEEHG+ FI + VP K+  +E G+PG+  V       +   +  +NTVL AIGRD CT +IGLE V + + +K G++ V +EEQ+ V  IYAIGDI+   ++LTPVAIQAG+ L++RL+ G  +  DY NVPTTVFTPLEYG+ GL+EE A+ K+G+E+IEV+H  F PLEWT+  R +N CY K+ICN  DN RVVGFHVL PNAGE+TQG+A A++ G TK+  D TIGIHP C+E FTTL++TK SGA   Q+GC G
Sbjct:   11 YDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLIVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVLLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASILQAGCUG 499          

Query:  409 YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDL-DKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC*G 1872
            Y+YDL++IGGGSGGLAA+KEAA +  KV VLDFV PTP GT WGLGGTCVNVGCIPKKLMHQ+ALL  +  D+R+YGWNV ETV+H W+ M E +QNHI SLNWGYR +LR K V Y NAYG F+  H IK T+    E+I ++  F+IATGERPRY  IPGDKEY I+SDDLFSL YCPGKTLV+GASYVALECAGFLA +GL VTVMVRSI LRGFDQ MANKIG++M+EHG+ FI + VP K+  +E G+PG+  V           +  +NTVL AIGRD CT +IGLENV + + +K G++ V EEEQ+ V  IYAIGDI+   L+LTPVAIQAG+ L++RL+GG  +  DY NVPTTVFTPLEYGS GL+EE A+ K+G+E++EV+H  F PLEWT+  R +N CY K++CN  DN RVVGFHVL PNAGE+TQG+A A++ G TK   D TIGIHP C+E FTTL++TK SG +  Q+GC G
Sbjct:   11 YDYDLIIIGGGSGGLAAAKEAAKYDKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALRDSRNYGWNVEETVKHDWERMTEAVQNHIGSLNWGYRVALREKKVTYENAYGEFVGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMQEHGIKFIRQFVPIKVEQIEAGTPGRLRVIAKSTDSDQTIEGEYNTVLLAIGRDACTRKIGLENVGVKINEKTGKIPVTEEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYGGSTVKCDYENVPTTVFTPLEYGSCGLSEEKAVEKFGEENVEVYHSYFWPLEWTIPSRDNNKCYAKVVCNIKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKDQLDSTIGIHPVCAEVFTTLSVTKRSGGNILQTGCUG 499          

Query:   91 MPPISTALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP+S+ L+ W+ + I SSV+IIFSKTTCPFC KIKK+LK+A IK+AAVE+NLL+   EIQDIL+ +TNQ+TVPNVFVRGTHIGGCD+AH AL+EG+IQ ++D+R+Y+YDLVVIGGGSGGLAASKEA+NFGAKVAVLDFV+PTP GTTWGLGGTCVNVGCIPKKLMHQSALLK +CEDA+SYGWN+PE +EH+W+NMV EIQNHIQSLNWGYR SLRNK VDYINAY  FIDEHTIK TDKYN+ R ITS+ F+IATGERP+YP+IPGDKEY ITSDDLFSL Y PGKTLV+GASYVALECAGF+A+LG KVTVMVRSIFLRGFDQQMANK+ +YM+ HG++FI ECVPTKIIPMEEGSPGKKEVFG Y+K+  EYKDWFNTVLFAIGRDPCT  IGL N+ +DLDKNGRV V  EEQ+ V N+YAIGDIIS GLQLTPVAIQAGKNL+RRL+GGE +LTDYVNVPTTVFTPLEYG IG  EEDAI K+G E+IEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRV+G HVL PNAGEITQGYA+AMRMGATKRDFDDTIGIHPTCSETFTTLNIT++SGADPAQSGC
Sbjct:    1 MPPVSSELKLWVEQTIKSSVMIIFSKTTCPFCRKIKKTLKEAKIKFAAVELNLLSNRQEIQDILFQLTNQKTVPNVFVRGTHIGGCDNAHAALSEGKIQNIIDQRKYDYDLVVIGGGSGGLAASKEASNFGAKVAVLDFVQPTPMGTTWGLGGTCVNVGCIPKKLMHQSALLKCACEDAKSYGWNIPEKLEHNWENMVTEIQNHIQSLNWGYRVSLRNKNVDYINAYAEFIDEHTIKATDKYNSTREITSDKFLIATGERPKYPDIPGDKEYCITSDDLFSLQYFPGKTLVVGASYVALECAGFIAALGGKVTVMVRSIFLRGFDQQMANKVAEYMKTHGIEFINECVPTKIIPMEEGSPGKKEVFGSYVKNNNEYKDWFNTVLFAIGRDPCTSNIGLGNINLDLDKNGRVKVTNEEQTNVENVYAIGDIISGGLQLTPVAIQAGKNLARRLYGGERVLTDYVNVPTTVFTPLEYGCIGWPEEDAISKFGAENIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVIGLHVLGPNAGEITQGYAVAMRMGATKRDFDDTIGIHPTCSETFTTLNITRSSGADPAQSGC 592          

Query:   91 MPPISTA-LEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL-DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP+    L+  +   +  + ++IFSKTTCPFC+K+K+  K  + +Y   E++ +A GS+IQ+ L  +T Q+TVPNVF+ G H+GGCDD  KA   G +Q +L D   Y+YDL+VIGGGSGGLAASKEAA+ G KVAV DFV+PTP GTTWGLGGTCVNVGCIPKKLMHQ+A+L HS EDA+ +GW VPE V+H+WD M   IQ+HI SLNWGYR  LR+K VDY NAY  FID+HT+K  +K   E   T+ +FI+A GERPRYP+IPG KEYGITSDDLFSL YCPGKTL+IGASYV+LEC GFL  +GL VTVMVRSI LRGFDQQMA+KIG+YME  G++FI +CVPTKI  +E+G PGK +V+G Y  D TEY D FNTV+FAIGRDP T  IGL+ V + L+K+G+V+ NE E + VSNIYAIGDI+   L+LTPVAIQAGK L+RRL+    +LTDYVNV TTVFTPLEYG+IG +EE AI K+G++++EV+H N+ PLEWTVA R +N CY K+IC+  D  RVVGFH+  PNAGEITQGYA+ M++GATK+DFDDTIGIHPTCSE FTTLN+TK SG    QSGC
Sbjct:    1 MPPVGAGGLKAEVMDQVAKNKVMIFSKTTCPFCFKVKEMFKSIDQEYGVTELDKIANGSDIQNTLLEVTGQKTVPNVFINGKHLGGCDDTLKAHKNGSLQAMLQDATNYDYDLIVIGGGSGGLAASKEAASLGKKVAVFDFVQPTPVGTTWGLGGTCVNVGCIPKKLMHQAAILGHSLEDAKHFGWKVPEDVQHNWDTMKNAIQDHIGSLNWGYRVQLRDKKVDYQNAYAEFIDDHTVKAVNKKGKEVTKTARDFIVAVGERPRYPDIPGAKEYGITSDDLFSLPYCPGKTLLIGASYVSLECGGFLHGIGLNVTVMVRSILLRGFDQQMADKIGEYMEAKGINFIRQCVPTKIEKLEDGQPGKYKVYGKY-SDGTEYSDTFNTVIFAIGRDPVTKTIGLDKVGVKLNKSGKVVANESEATNVSNIYAIGDILEGKLELTPVAIQAGKLLARRLYDNSKVLTDYVNVATTVFTPLEYGAIGYSEEAAIEKFGEDNVEVYHTNYWPLEWTVAKREENVCYAKIICHIPDKERVVGFHICGPNAGEITQGYALGMKLGATKKDFDDTIGIHPTCSEQFTTLNVTKRSGKMVNQSGC 593          

Query:   91 MPPISTA---LEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDE--RQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            M PI+TA     + + K I  + ++IFSK+ CPFC+K+K   K  N+ Y  +E++++  GSEIQ  L   + QRTVPNV++ G H+GG DD     A G + KL+++    Y+YDLVVIGGGSGGLAASKEAAN GAKVAV DFV+PTP+GTTWGLGGTCVNVGCIPKKLMHQ+A+L+   +D+R YGW  PE + H W+ MVE IQNHI SLNWGYR +LR+K VDY+NAY  F+D+HT+KT D+   E+ ITS+  ++ATG RPRYP+IPG KE+ ITSDD+FSLSY PGKTL++GASY++LECAGFLA LG  VTVMVRSI LRGFDQQMA +IG YME+HGV FI   VPT I  +EEGSPG  +V     + + E    +NTV+ AIGRDPCT  IGL+ + I++ K+G+V+V+E EQ++V +IYA+GDII  G +LTPVAIQAG+ L+RRL+G   +LTDY  VPTTVFTPLEYG  GL+EE AI ++G+E+IEVFH N++PLE+TVAHR +NDCY KL+C K++N RV+GFHVL PNAGEITQG+AI +++ ATK DFD+ IGIHPT +E FTTL++TK+SG D A  GC
Sbjct:   78 MAPINTAGLQPAQVVEKCIAENKVMIFSKSFCPFCHKVKDLFKSLNVPYEVLELDIVENGSEIQGALLEKSGQRTVPNVYISGEHVGGADDTFATHARGDLMKLVNKGAHSYDYDLVVIGGGSGGLAASKEAANLGAKVAVCDFVQPTPRGTTWGLGGTCVNVGCIPKKLMHQAAILQEGLKDSREYGWETPEGITHDWNKMVEAIQNHIGSLNWGYRVALRDKKVDYLNAYATFVDDHTLKTVDRRGKEKTITSDKILLATGGRPRYPDIPGAKEHCITSDDIFSLSYAPGKTLLVGASYISLECAGFLAGLGYDVTVMVRSILLRGFDQQMAERIGTYMEKHGVKFIRGAVPTAIEQVEEGSPGLLKVTAQSTEGE-EVVGEYNTVVVAIGRDPCTASIGLDKLDINMAKSGKVVVDEREQTSVPHIYAVGDIIEGGHELTPVAIQAGRLLARRLYGNGTLLTDYDKVPTTVFTPLEYGCCGLSEEVAIERHGEENIEVFHSNYQPLEFTVAHRPENDCYAKLVCLKTENNRVLGFHVLGPNAGEITQGFAIGLKLNATKADFDNLIGIHPTTAEIFTTLSVTKSSGQDVAAQGC 673          

Query:   91 MPPISTAL--EEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDER--QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP+ T L   E + + I  + +++FSK+TCPFC+K+K   K+ NI +  +E++ ++ G+ +Q+ L   T Q TVPN ++ GTH+GG  D  +  ++G + KLL  R   YEYD+V+IGGGSGGLAASKEAA  GAKVAV+DFVKPTP GTTWGLGGTCVNVGCIPKKLMHQ+A+L H  ED+ ++GW  PE + H W  +VE +Q+HI SLNWGYR  LR+K VDYINAY  F D HT++T D+   ER IT++  ++A G RPRYP+IPG KEY ITSDD+FSL + PGKTL++GASY+ALECAGFLA+LG  VTVMVRSIFLRGFDQQMANKI +YME+ GV FI   VPTK+  +E GSPG   V              +NTV+ AIGRDPCT  IG+EN   +L KNG++IV++ E+S V +IY IGD+I  GL+LTPVAIQAGK LS+R+F       DY NVPTTVFTPLEYG  GL+EE AI KYG++ +E++H NF PLE+TVAHR +NDCY KLIC KS N  VVGFH+L PNAGEITQGYAIA++M ATK +FDD +GIHPTC+ET TT+NITK SGADPA SGC
Sbjct:   67 MPPLPTDLPAAELVEQYIKQNKIVVFSKSTCPFCHKVKGLFKELNIAFTVLELDQISNGAAVQEALQAKTGQTTVPNTWINGTHVGGATDTLELHSKGELMKLLRTRTHSYEYDMVIIGGGSGGLAASKEAAKLGAKVAVVDFVKPTPSGTTWGLGGTCVNVGCIPKKLMHQAAVLSHCLEDSVAFGWKTPEKISHDWAALVEGVQSHIGSLNWGYRVQLRDKKVDYINAYAKFTDPHTLQTVDRRGKERTITADQIVLAAGGRPRYPDIPGAKEYCITSDDIFSLPHAPGKTLLVGASYIALECAGFLANLGYDVTVMVRSIFLRGFDQQMANKIAEYMEKQGVKFIRGAVPTKVEQIEAGSPGTLRVTAAPTDGGEAITGEYNTVVVAIGRDPCTSDIGIENTGAELAKNGKLIVDDVERSNVPHIYGIGDMIEGGLELTPVAIQAGKLLSKRIFADATKKMDYRNVPTTVFTPLEYGCCGLSEEAAIAKYGEDDLEIYHTNFWPLEFTVAHRPENDCYAKLICVKSQNELVVGFHILGPNAGEITQGYAIALQMKATKENFDDLVGIHPTCAETLTTMNITKKSGADPAASGC 662          

Query:   91 MPPISTA-----LEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD--ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPPI        L+  I+++I+S+ +++FSK+ CP+C K+K   K+  ++   VE++L+  G+  Q++L  +T Q+TVPNVF+  TH+GGCD   +A  +G +Q+LL+     Y+YDL+VIGGGSGGLA SKEAA  G KV VLD+V PTP+GT+WGLGGTCVNVGCIPKKLMHQ+ALL+ + +DAR +GW   ETV+H+W+ M E I N+I SLNWGYR +LR+K VDY+NAY  FID H IKTT+K   E   T+  F++ATGERPRY NIPGDKE+ ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VTVMVRSI LRGFDQ MAN+ G+YMEEHGV F+ E VPTKI  +E G+PG+ +V       +   +  +NTVL A+GRD CTD+IGL+ V + ++ KNG++ VN+EEQ+ V +IYAIGDI+    +LTPVAIQAGK L+RRL+GG     DYVNVPTTVFTP+EYG+ GL+EE A+G YG+E+IEVFH  F PLE+TV  R +N CY K+ICNK DN RV+GFH L PNAGE+TQG++ AM+ GATK   D TIGIHPTC+E FTT+ +TK+SG +  QSGC
Sbjct:    1 MPPIENESGKNDLKSRIQQLIDSNQVMVFSKSYCPYCVKVKDLFKELQVECNVVELDLIEDGTNYQEMLLEMTGQKTVPNVFINKTHVGGCDKTLQAHKDGSLQQLLNGQNESYDYDLIVIGGGSGGLACSKEAALLGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLMHQTALLRTAIQDARKFGWEFDETVKHNWETMKEAINNYIGSLNWGYRVALRDKMVDYVNAYAEFIDPHKIKTTNKRGKETFYTAARFVLATGERPRYLNIPGDKEHCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGEYMEEHGVKFLREYVPTKIEELEAGTPGRLKVTAKSTGSEEVIEGEYNTVLIAVGRDACTDKIGLDKVGVKVNPKNGKIPVNDEEQTNVPHIYAIGDILQDKWELTPVAIQAGKLLARRLYGGSKAKCDYVNVPTTVFTPMEYGACGLSEERAVGLYGQENIEVFHTLFWPLEFTVPSRDNNKCYAKIICNKLDNDRVIGFHYLGPNAGEVTQGFSTAMKCGATKEQLDGTIGIHPTCAEIFTTMEVTKSSGGNINQSGC 600          

Query:   91 MPPIST-----ALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPP+        ++  I+++I+++ +++FSK+ CP+C K+K+   D N++   +E++L+  GS  QD+L  +T Q+TVPNVFV  TH+GGCD+  KA  +G +Q+LL ++   Y+YDL+VIGGGSGGLA SKEAAN G KV VLD+V PTP+GTTWGLGGTCVNVGCIPKKLMHQ+AL+  + +DAR +GW   E V H+W+ M   + N+I SLNWGYR SLR+K V+Y+N+Y  F++ H IK T++   E   T+  F++ATGERPRY  IPGDKEY ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VT+MVRSI LRGFDQ MAN+ G +ME HGV F+ + VP K+  +E G+PG+ +V     +    ++  +NTVL A+GRD CT++IGL+   + ++ KNG++ VN+EEQ+ + +IYAIGDI+    +LTPVAIQAGK L+RRL+ G  +  DYVNVPTTVFTPLEYGS G  EE A+  YG+E++EV+H  F PLE+TV +R +N CY K+ICNK D+ RV+GFH L PNAGE+TQG+  AM+ G TK   D+TIGIHPTC+E FTT+ +TK SG D  Q+GC
Sbjct:    1 MPPVEIDAGRDQIKARIQELIDTNSVVVFSKSYCPYCTKVKELFNDLNVECNIIELDLMENGSNFQDLLMEMTGQKTVPNVFVNKTHVGGCDNTIKAHKDGLLQQLLGDKSEVYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWEFSEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMETHGVKFLRKFVPVKVEELEAGTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQAGVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYGSCGHPEERAVELYGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRSGGDITQAGC 600          

Query:  385 QKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASG 1842
            Q+LL ++   Y+YDL+VIGGGSGGLA SKEAAN G KV VLD+V PTP+GTTWGLGGTCVNVGCIPKKLMHQ+AL+  + +DAR +GW   E V H+W+ M   + N+I SLNWGYR SLR+K V+Y+N+Y  F++ H IK T++   E   T+  F++ATGERPRY  IPGDKEY ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VT+MVRSI LRGFDQ MAN+ G +ME HGV F+ + VP K+  +E G+PG+ +V     +    ++  +NTVL A+GRD CT++IGL+   + ++ KNG++ VN+EEQ+ + +IYAIGDI+    +LTPVAIQAGK L+RRL+ G  +  DYVNVPTTVFTPLEYGS G  EE A+  YG+E++EV+H  F PLE+TV +R +N CY K+ICNK D+ RV+GFH L PNAGE+TQG+  AM+ G TK   D+TIGIHPTC+E FTT+ +TK SG
Sbjct:    1 QQLLGDKSEVYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWEFSEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMETHGVKFLRKFVPVKVEELEAGTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQAGVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYGSCGHPEERAVELYGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRSG 489          

Query:  385 QKLLDERQ--YEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            Q+LL ++   Y+YDL+VIGGGSGGLA SK       KV VLD+V PTP+GTTWGLGGTCVNVGCIPKKLMHQ+AL+  + +DAR +GW   E V H+W+ M   + N+I SLNWGYR SLR+K V+Y+N+Y  F++ H IK T++   E   T+  F++ATGERPRY  IPGDKEY ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VT+MVRSI LRGFDQ MAN+ G +ME HGV F+ +   +       G+PG+ +V     +    ++  +NTVL A+GRD CT++IGL+   + ++ KNG++ VN+EEQ+ + +IYAIGDI+    +LTPVAIQAGK L+RRL+ G  +  DYVNVPTTVFTPLEY             YG+E++EV+H  F PLE+TV +R +N CY K+ICNK D+ RV+GFH L PNAGE+TQG+  AM+ G TK   D+TIGIHPTC+E FTT+ +TK SG D  Q+GC
Sbjct:    1 QQLLGDKSEVYDYDLIVIGGGSGGLACSK-------KVMVLDYVVPTPKGTTWGLGGTCVNVGCIPKKLMHQTALMGTALQDARKFGWEFSEQVSHNWETMKTAVNNYIGSLNWGYRVSLRDKNVNYVNSYAEFVEPHKIKATNRRGKETFHTAAKFVLATGERPRYLGIPGDKEYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTIMVRSILLRGFDQDMANRAGDHMETHGVKFLRKFCSS-------GTPGRLKVTAKSTETDEIFEGEYNTVLIAVGRDACTEKIGLDQAGVKVNPKNGKIPVNDEEQTNIPHIYAIGDILEGKWELTPVAIQAGKLLARRLYAGASLKCDYVNVPTTVFTPLEYEL-----------YGQENLEVYHSLFWPLEYTVPNRDNNRCYAKIICNKLDDNRVIGFHYLGPNAGEVTQGFGAAMKCGVTKEQLDNTIGIHPTCAEIFTTMEVTKRSGGDITQAGC 472          

Query:  586 MHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGR-VIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MHQ+ALL  + +DA+ YGW +P+ V H W  + E +QN+++SLNWG+R  L+++ V Y+N  G+ +D+HT++       E  +T+ N +IATG RP+YP ++PG  E+GI+SDDLF L   PGKTLV+GASYV LECAGFL  +GL+ TVMVRSI LRGFDQQM+  +  YM+ +G  F  +CVP K+   E+   G  +V     +   +++D FN+VL+A+GR P T  + L+ V ++LD + R V+V ++E+++V NIYAIGDI     +LTP AI AGK L+RRL G    L DY NVPTTVFTPLEYG +GL+EE+A  +YGK+ +EV+H  +KPLE+TVA R    CY K++C +  + +VVG H   PNAGE+TQG+A+++R G +     D++GIHPTC+E  T + ITK SG D   +GC
Sbjct:    1 MHQAALLGSAVKDAQKYGWQIPQPVSHDWATLAESVQNYVKSLNWGHRVQLQDRKVKYMNMKGSLVDDHTVRCLSSRGKEMTVTARNILIATGGRPKYPTHVPGALEFGISSDDLFWLKETPGKTLVVGASYVGLECAGFLTGIGLEATVMVRSIALRGFDQQMSRLVTDYMQGYGTRFCWDCVPKKV---EKLPSGLLQVTWTDSRTGQDHQDTFNSVLWAVGRAPETGTLNLQQVGVELDGDTRKVMVADDERTSVPNIYAIGDIAQGRPELTPTAIHAGKLLARRLAGLSSQLMDYSNVPTTVFTPLEYGCVGLSEEEAERRYGKDKVEVYHAFYKPLEFTVAERELRQCYIKVVCERDGDQKVVGLHFTGPNAGEVTQGFALSLRCGLSYAQLRDSVGIHPTCAEELTKIYITKRSGLDATVTGC 426          

Query:  586 MHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGR-VIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MHQ+ALL  + +DA+ YGW +P+ V H W  + E +QN+++SLNWG+R  L+++ V Y+N  G+ +D+HT++       E  +T+ N +IATG RP+YP ++PG  E+GI+SDDLF L   PGKTLV+GASYV LECAGFL  +GL+ TVMVRSI LRGFDQQM+  +  YM+ +G  F  +CVP K+   E+   G  +V     +   +++D FN+VL+A+GR P T  + L+ V ++LD + R V+V ++E+++V NIYAIGDI     +LTP AI AGK L+RRL G    L DY NVPTTVFTPLEYG +GL+EE+A  +YGK+ +EV+H  +KPLE+TVA R    CY K++C +  + +VVG H   PNAGE+TQG+A+++R G +     D++GIHPTC+E  T + ITK SG D   +GC
Sbjct:    1 MHQAALLGSAVKDAQKYGWQIPQPVSHDWATLAESVQNYVKSLNWGHRVQLQDRKVKYMNMKGSLVDDHTVRCLSSRGKEMTVTARNILIATGGRPKYPTHVPGALEFGISSDDLFWLKETPGKTLVVGASYVGLECAGFLTGIGLEATVMVRSIALRGFDQQMSRLVTDYMQGYGTRFCWDCVPKKV---EKLPSGLLQVTWTDSRTGQDHQDTFNSVLWAVGRAPETGTLNLQQVGVELDGDTRKVMVADDERTSVPNIYAIGDIAQGRPELTPTAIHAGKLLARRLAGLSSQLMDYSNVPTTVFTPLEYGCVGLSEEEAERRYGKDKVEVYHAFYKPLEFTVAERELRQCYIKVVCERDGDQKVVGLHFTGPNAGEVTQGFALSLRCGLSYAQLRDSVGIHPTCAEELTKIYITKRSGLDATVTGC 426          

Query:   91 MPPISTALEEW---IRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLD-----------------ERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGA 1845
            MPP   A E     ++ ++    +++FSK+ CPFC K+K    +  + Y A+E++L+  G  IQ++L  +T Q+TVPNVFV  TH+GGCD   +A   GR+Q+LL                     YEYDL+VIGGGSGGLAASKEAA  G KV VLDFV+PTP GT+WGLGGTCVNVGCIPKKLMHQ+ALL H+  D+R +GW   + V H+W  M E IQN+I SLNWGYR +LR+  V Y+NA+G F D H IK T+K   E   T+  FI+A GERPRY  IPGDKE+ ITSDDLFSL YCPGKTLV+GASYVALECAGFLA LGL VTVMVRSI LRGFDQQMA   G YME+HGV FI + VPTK+  +E G+PG+ +V     +    Y+  FNTVL A+GRD CT  IGL+ V + +D + G+V VN+ EQ+ V ++YAIGDI+   L+LTP+AIQAG+ L++RL+GG     DYVNV TTVFTPLEYG  GL+EE AI   G ++IEVFH NF PLEWTVA   +N CY K++CNK+D  RVVGFHVL PNAGEITQG+ +AM+ G TK   DDTIGIHPTC+E       T  S A
Sbjct:    1 MPPTGEAREAARTRVQGLVERVPVVLFSKSFCPFCEKVKGLFTELKVSYEALELDLIDDGPLIQEVLLEMTGQKTVPNVFVNKTHVGGCDKTIQAYQSGRLQQLLAASTAPSPAPPVEDTDAVRHSYEYDLIVIGGGSGGLAASKEAAKLGKKVMVLDFVQPTPLGTSWGLGGTCVNVGCIPKKLMHQAALLGHALSDSRKFGWEYDQQVTHNWSTMKEAIQNYIGSLNWGYRVALRDHAVSYVNAFGTFTDAHAIKATNKRGKETQHTAETFILAMGERPRYLGIPGDKEFCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGLGLDVTVMVRSILLRGFDQQMAELAGDYMEKHGVKFIRQFVPTKVEQLEAGTPGRLKVHAKATEGSELYEGEFNTVLIAVGRDACTSNIGLDVVGVKVDERTGKVPVNDVEQTNVPHVYAIGDILQGKLELTPIAIQAGRLLAQRLYGGGTTKCDYVNVCTTVFTPLEYGCCGLSEERAIELLGGDNIEVFHSNFWPLEWTVAGGDNNSCYAKILCNKADKDRVVGFHVLGPNAGEITQGFGVAMKCGLTKAQLDDTIGIHPTCAEVGRAHTATHRSTA 606          

Query:  397 DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSC--EDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATG-ERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM--VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE-HILTDYVNVPTTVFTPLEYGSIG-----LAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASG 1842
            D+   + D+ VIG G GG  A+ +AA  G KV  ++            LGGTC+NVGCIP K +  ++   H    +D  S G  + + ++ + + M+E+    +++L  G     +   V ++  +G    ++ +       ++++I + N +IATG E   +  I  D+E  ++S    SL   P K +VIGA  + +E       LG +VT +  +  +   G D +++    + +++ G+ F    + TK++     + GK +V     K         + +L  +GR P T  +GLE + I LD  GRV +N   Q+++ NIYAIGD ++ G  L   A   G      + GG  HI  DY  VP+ ++T  E   IG     L EE    K GK     F  N +          D D   K++ +K  + R++G H+L   AGE+    A+AM  GA+  D       HPT SE F   N+    G
Sbjct:   35 DKAPLDADVTVIGSGPGGYVAAIKAAQLGFKVICVE--------KNETLGGTCLNVGCIPSKALLNNSYFYHLAHGKDFASRGIEI-QGLKLNLEKMMEQKSGAVKALTGGIAHLFKQNKVTHVKGHGMITGKNQVTAACADGSQQVINTKNILIATGSEVTPFQGIEVDEETVVSSTGALSLKQVPEKLVVIGAGVIGVELGSVWQRLGAEVTAVEFLGHVGGAGIDMEISKNFQRILQKQGMKFK---LSTKVMAASRRADGKIDVQTEPAKGGAADTLTCDVLLVCVGRRPFTAGLGLEELGIALDNRGRVPINNRFQTSIPNIYAIGDAVA-GPMLAHKAEDEGIICVEGMAGGAVHI--DYNCVPSVIYTHPEVAWIGKNEEQLKEEGVPYKIGKFP---FAANSR-----AKTNADTDGLVKILAHKETD-RMLGAHILGSGAGEMINEAALAMEYGASCEDVARVCHAHPTVSEAFREANLAATFG 503          

Query:  415 YDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGW--NVPETVEH---SWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVR-SIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILT---DYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            YD +VIGGGSGG+A+++ AA++GAK  +++            LGGTCVNVGC+PKK+M  ++ L      A  YG   N+P   EH   +W    ++   ++  LN  Y+ +L  + VD +  +  F  +  ++   + N   + ++N+ ++ATG +  +P NIPG  E G  SD  F L   P K +V+GA Y+ +E AG    LG +  +++R    LR FD+ + N I  +  + G++       +KI+ +E+     K     ++ D     D  + +++ IGR      +G ENV I L+ + ++I +E + + V NIY++GD++ + ++LTPVAI AG+ LS RLFG E       DY NVP+ +F+  E GSIG++E++AI KYGKE+I+V++  F  + + +        Y K++C    N +VVG H++  ++ EI QG+ +A++MGATK DFD+ + IHPT +E   T+
Sbjct:   24 YDYLVIGGGSGGVASARRAASYGAKTLLVE---------AKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHK---LSKIVKVEKNVETDK--LKIHMNDSKSIDD-VDELIWTIGRKSHLG-MGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVVGK-VELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNSKFTAMYYAMLSEKSPTRY-KIVC-AGPNEKVVGLHIVGDSSAEILQGFGVAIKMGATKADFDNCVAIHPTSAEELVTM 482          

Query:  415 YDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKK-LMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTD------KYNNERIITSNNFIIATG-ERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM-VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKD-KTEYKDWFNT--VLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEED--------AIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKL-ICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNIT 1830
            +D+V+IGGG  G  A+ +AA  G   A ++            LGGTC+NVGCIP K L++ S L      +A+  G +V   ++ +  N  +   + ++ L  G     +   V Y    G+F DE  I+ T           + I+   N I+ATG E   +P I  D+E  ++S    SL   P +  +IG   + LE     + LG KVTV+  +       D ++A    K++++ G+DF    + TK+I  +      K V    ++D KT  ++      +L A+GR P    +G E + +++DK GR++++++  S   +I  +GD+ + G  L   A + G      L  G H   +Y N+P+ +++  E   +G  EE          IGK+             P       + + D  G + I   S   R++G H++ PNAGE+     +A+  GA+  D       HPT SE F   N+ 
Sbjct:   27 HDVVIIGGGPAGYVAAIKAAQLGFNTACVE--------KRGKLGGTCLNVGCIPSKALLNNSHLFHQMHTEAQKRGIDVNGDIKINVANFQKAKDDAVKQLTGGIELLFKKNKVTYYKGNGSFEDETKIRVTPVDGLEGTVKEDHILDVKNIIVATGSEVTPFPGIEIDEEKIVSSTGALSLKEIPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDF---KLSTKVISAKRND--DKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGAEKIGLEVDKRGRLVIDDQFNSKFPHIKVVGDV-TFGPMLAHKAEEEGIAAVEMLKTG-HGHVNYNNIPSVMYSHPEVAWVGKTEEQLKEAGIDYKIGKF-------------PFAANSRAKTNQDTEGFVKILIDSKTERILGAHIIGPNAGEMIAEAGLALEYGASAEDVARVCHAHPTLSEAFKEANMA 491          

Query:  373 EGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEE--IQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERP-RYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM-VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVI-VNEEEQSTVS--NIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEE---DAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLI--CNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETF-TTLNITKASGADP 1851
            E  I   +++    YD++VIG G GG  A+ +A+  G   A +D            LGG  +  G +P K +   + L    +                +D    +  ++++I+ L   Y+  L    V       AF D H ++   +     I+ +   ++ATG    + P +  D +  I+SD   SL Y P +  ++G   + LE A    +LG +VT++  +S   +  D ++A+     ++  G+ F+ +   T++   E  + G+  +       K  Y    + ++ +IGR P     GL+   I LD+   V  V+ + QS +   +I  IGD+    +       QA + +      G    ++    P  ++   + G +G  EE    A   Y K  + +F QN +    T+  R +N      I     S +M+++G H+++ +A E+    ++A+ +G T  D       HP+ SE+F   + +  A+G  P
Sbjct:    4 EDEILSTMEDFAAVYDVLVIGCGPGGFTAAMQASQAGLLTACVD--------QRASLGGAYLVDGAVPSKTLLYESYLYRLLQQQELIEQRGTRLFPAKFDMQAAQSALKHNIEELGNVYKRELSKNNVTVYKGTAAFKDPHHVEIAQRGMKPFIVEAKYIVVATGSAVIQCPGVAIDNDKIISSDKALSLDYIPSRFTIMGGGTIGLEIACIFNNLGSRVTIVESQSEICQNMDNELASATKTLLQCQGIAFLLD---TRVQLAEADAAGQLNITLLNKVSKKTYVHHCDVLMVSIGRRPLLK--GLDISSIGLDERDFVENVDVQTQSLLKYPHIKPIGDVTLGPMLALKAEEQAIRAIQSIGCTGSDGTSNCGFPPNVLYCQPQIGWVGYTEEGLAKARIPYQKGRV-LFSQNVR--YNTLLPREENTTVSPFIKVLIDSRDMKILGVHMINDDANELLSQASMAVSLGLTAHDVCKVPFPHPSLSESFKQAVQLAMANGTSP 493          

Query:  100 ISTALEEWIRKIINSSVLIIFSKTTCPFCYK----IKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDD 354
            +S    + ++ +I  + + + SKT CP+C+     + + LK    K   +++N +  G++IQ  LY I  QRTVPN+++ G HIGG DD
Sbjct:    2 VSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDD 90          

Query:  124 IRKIINSSVLIIFSKTTCPFCYKIKKSL-KDANI---KYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL 396
            ++ +I    + + +KT CP+C     +L ++ N+   K   +E++ ++ GSEIQD L  I+ Q+TVPNV++ G HIGG  D       G++ ++L
Sbjct:   44 VKDLIGQKEVFVAAKTYCPYCKATLSTLFQELNVPKSKALVLELDEMSNGSEIQDALEEISGQKTVPNVYINGKHIGGNSDLETLKKNGKLAEIL 138          

Query:   91 MPPISTALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL--DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            M P+   ++  I   IN++ ++IFSK+ CPFC K+K   +  N++Y A+E++L+  G  IQ+ L   + Q+TVPNV++RG H+GG D   K   E +I  L+      YEYDL+VIGGGSGGLA +KEAA  G KVAVLDFVKPTP+GTTWGLGGTCVNVGCIPKKLMHQ+ALL  + +DAR YGW   E V+H+W+++ E +QNHI SLNWGYR  LR K V Y NA+G FID HTIK TDK   E I+T+  F++A G RPRYPNIPG KEYGITSDDLFSL YCPG T++IGASYV+LECAGFLA++GL VTV+VRSI LRGFDQQMA K G +ME HGV F    VPTK+  +EEGSPGK  V       +  + D  NTV+FAIGRD CT  IGLE V + L+ KN +VI  + EQS+V NIYAIGDI+   L+LTPVAIQAG+ LSRRL+  +  L DY+NV TTVFTPLEYG+IG +EEDAI K+G+E++EV+H  F+PLE+TVA R  +DCY KLICNK+D+ RVVGFHVL PNAGEITQGYA+A + GATK  FDDTIGIHPTCSETFT L++TK SGA    SGC
Sbjct:    1 MAPVPQ-IQRLIEDSINNNAVMIFSKSFCPFCKKVKAIFESINVQYTAMELDLVDNGPAIQEALLEKSGQKTVPNVYIRGNHVGGSDIITKLQEENKILGLIIPPSASYEYDLIVIGGGSGGLACAKEAAQLGRKVAVLDFVKPTPKGTTWGLGGTCVNVGCIPKKLMHQAALLGEALKDARLYGWEFDEKVKHNWESLREGVQNHIGSLNWGYRVQLREKSVTYKNAFGEFIDNHTIKATDKRGTETIMTAETFVLAMGLRPRYPNIPGAKEYGITSDDLFSLPYCPGTTVLIGASYVSLECAGFLAAMGLDVTVVVRSILLRGFDQQMAEKAGSFMETHGVKFKRPAVPTKVEQLEEGSPGKLRVHYKLEGGEEGHLDC-NTVVFAIGRDACTTGIGLEKVGVKLNPKNQKVIAGDNEQSSVPNIYAIGDILDGKLELTPVAIQAGRLLSRRLYRNDTKLCDYINVATTVFTPLEYGAIGYSEEDAIQKFGQENVEVYHTLFQPLEYTVAQRSKDDCYAKLICNKADSERVVGFHVLGPNAGEITQGYAVAFKCGATKEHFDDTIGIHPTCSETFTLLDVTKRSGASIVSSGC 593          

Query:  415 YDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            YDLVVIGGGSGGLA SKEAA+ G KVAVLDFV P+PQG+TWG+GGTCVNVGCIPKKLMH ++LL    +DA+ YGW + + +   W N+V  +QN+I+SLNWGYR  L +K V YI    +F+D HTIK   K   E ++TS   +IA G RPR+P ++PG KEY ITSDDLFSL   PGKTLVIGASYVALECAGFLA  G   ++M+RSI LRGFDQQMA+ + +YM  HG  FI +CVP  +   ++   GK  V           ++ F+TVL AIGRDP T  + L+   + +DK+G +I  E EQ++  NIYA+GD++    +LTPVAI AGK L+RRLF G  I  DY NV       L +         +I K  K       + +  +     + G         C   D   +     L+P  G       +  R G T R    T+GIHPTC+E    L+ITK SG DP  +GC
Sbjct:    1 YDLVVIGGGSGGLACSKEAASLGKKVAVLDFVAPSPQGSTWGIGGTCVNVGCIPKKLMHHASLLGDGIKDAKKYGWQLSDQMTFDWGNLVTGVQNYIKSLNWGYRVQLHDKSVRYIPGMASFVDRHTIKAVLKSGKEELLTSEKVVIAVGGRPRFPSDVPGAKEYCITSDDLFSLQKPPGKTLVIGASYVALECAGFLAGFGYNTSLMMRSIPLRGFDQQMASLVTEYMSRHGTRFINQCVPVSV---DKRPDGKLHVQWTNPSSGERGEEEFDTVLMAIGRDPSTAALELDKAGVQVDKSGFIIGMENEQTSAKNIYALGDVLQDRPELTPVAIMAGKLLARRLFAGSTIQMDYDNVRILSLRRLLH---------SINKAAKAEEHAPVRLYSMMSLLTPYWG---------CTTGD---LYTRPSLNPLLG-------MYYRCGLTMRMLSSTVGIHPTCAEEVVKLHITKRSGEDPTVTGC 454          

Query:  463 KEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVR-SIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDW--FNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE-HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            + AA FG K  V++  +         LGGTCVNVGC+PKK+M  +A+   +    + YG++V    + +W N+ E+   H+  LN  Y  +L    VD++  +  F  +  +K  D     ++ +  + +IATG  P  P+IPG  E+GITSD  F L   P K  V+GA Y+A+E AG L +LG +V++++R +  +R FD  ++  + + +++ G+D  T     ++   ++ + G   +    +K+KTE  D   ++ +L+A+GR+P T+ +GLE++ I++DK G +IV+E + +T  N+YA+GD+  + L LTPVAI AG+ L+ RLF G+ ++  DYVN+PT VF+    G+IGL EE A  +YGK+ ++++   F  + + V  +  +  + KLI    +  +V+G H+L   A E+ QG+A+A++MGATK DFD+ + IHPT SE   T+
Sbjct:   23 RRAAEFGVKAVVIEHAR---------LGGTCVNVGCVPKKIMFNAAMCAETLPYYKDYGFDVILN-KFTWKNIKEKRDAHVSKLNTIYENNLGKAHVDFVAGHAQFTPDGNVKVGD-----QLFSGKHILIATGGVPSLPSIPG-FEHGITSDGFFELEDLPKKVAVVGAGYIAVELAGILNALGSRVSLLIRYNNVIRNFDSMLSGMLTEEIKDSGIDLCTNTTTEQV--SKDSNTGLLTLH--TLKNKTEKVDLSGYDCLLWAMGRNPNTNNLGLEHMGIEMDKGGHIIVDEFQNTTRKNVYALGDVCGKAL-LTPVAISAGRKLAHRLFDGQTNLKLDYVNIPTVVFSHPTIGTIGLTEEQAAQQYGKDKLKIYKSTFVNMYYAVTDK-KHKTHMKLITLLPEE-KVIGLHILGLGADEMLQGFAVAIKMGATKADFDNAVAIHPTSSEELVTM 456          

Query: 1396 QLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +LTPVAI AGK L+RRLF G  I  DY N+ TTVFTPLEY ++GL+EEDAI +YG+E++EV+H  +KPLE+ V  R ++  Y K +C +     V+G H L PNAGE+ QG+A+A+R G T R    T+GIHPTC+E    L+ITK SG DP  +GC
Sbjct:   21 ELTPVAIMAGKLLARRLFAGSTIQMDYDNIATTVFTPLEYSTVGLSEEDAIRQYGEENLEVYHAFYKPLEFRVTEREEDVGYIKAVCLREGEQSVIGLHYLGPNAGEVMQGFAVAIRCGLTMRMLSSTVGIHPTCAEEVVKLHITKRSGEDPTVTGC 177          

Query:  388 KLLDERQY----EYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKH--SCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATG-ERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM--VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDW-FNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE-HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYG--KLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASG 1842
            +++  R Y    E DLVVIG G GG  A+ +AA  G K   ++            LGGTC+NVGCIP K +  ++ L H  S  D ++ G  +   V  + D M+ + +N +++L  G     +   V  ++  G   D + +       +  +I + N +IATG E   +P I  D+++ I+S    SLS  P   ++IGA  + +E     + LG  VT +  +  I   G D +++    + +++ G+ F    + TK+   E  S G   V     KD ++ ++   + +L  IGR P T R+GLE V I LD  GRV+VNE+ Q+ V NIYAIGD I  G  L   A   G      + GG  HI  DY  VP  V+T  E   +G  EE       +E +E     F P+      R + +  G  K++ +K  + R++G H++ P AGE+    A+AM  GA+  D       HPT SE F   N+   +G
Sbjct:   31 RVVSSRNYSTEGEVDLVVIGSGPGGYVAAIKAAQLGMKTVSVE--------KNMSLGGTCLNVGCIPSKALLNNSHLYHQASGADFKNRGIEM-SGVTLNLDQMMSQKENAVKALTNGIAHLFKQNKVTQVHGRGTITDTNEVTVYKDDLSTEVIKTKNILIATGSEVTPFPGIEIDEKHIISSTGALSLSTVPKNLVLIGAGVIGVELGSVWSRLGANVTAVEFLGHIGGIGIDMEISKNFQRILQKQGMKFK---LNTKVTGAERTSDGVV-VSVESAKDGSKKEELEADVLLVCIGRRPYTTRLGLEKVGIPLDSRGRVVVNEKFQTNVPNIYAIGDCI-HGPMLAHKAEDEGIICVEGMNGGAVHI--DYNCVPNVVYTHPEVAWVGKTEE----MLKEEGVEYKVGKF-PMSANSRARTNAEIDGMVKVLGDKETD-RLLGVHMICPGAGELINEAALAMEYGASCEDIARVCHAHPTVSEAFREANLAAYAG 506          

Query:   91 MPPI-----STALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL--------DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPPI        L+  I+++I S+ +++FSK++CPFC ++K   K+  ++   VE++L+  G+  Q++L  +T Q+TVPNVF+   H+GGCD   +A  +G +Q+LL        +++ Y+YDL+VIGGGSGGLA SKEAAN G KV VLDFV+PTP+GTTWGLGGTCVNVGCIPKKLMHQ+ALL  + +DAR +GW   E+V+H+W+ M   + N+I SLNWGYR +L++K V+Y+NAY  F++ H IK T+K   E   T+  F++ATGERPRY +IPGD+EY ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VTVMVRSI LRGFDQ MAN+ G +MEEHGV FI + VP KI  +E GSPG+ +V     +     +  +NTVL A+GR+ CT+RIGL+   + ++ KNG++ VN+EEQ+ V +IYAIGDI+    +LTPVAIQAGK L+RRL+G   +  DY+NVPTTVFTP+EYGS GL EE A+  YG E+IEV+H  F PLE+TVA+R +N CY K+I NK DN RV+GFH L PNAGE+TQG+  AM+ G TK   D TIGIHPTC+E FTTL +TK+SG D  Q+GC
Sbjct:    1 MPPIGNDAGKNDLKMRIQQLIESNAVMVFSKSSCPFCVRVKDLFKELKVECNVVELDLIEEGTNYQEMLLELTGQKTVPNVFINKKHVGGCDKTMQAHRDGSLQRLLGGQTEENQEDQTYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDFVEPTPKGTTWGLGGTCVNVGCIPKKLMHQTALLGTALQDARKFGWEFDESVKHNWETMKTAVNNYIGSLNWGYRVALKDKNVNYVNAYAEFVEPHKIKATNKRKKETFYTAAKFVLATGERPRYLDIPGDREYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGDHMEEHGVKFIRKFVPVKIEELEAGSPGRLKVTAKSTETDEIIEGEYNTVLIAVGRNACTERIGLDKAGVRVNPKNGKIPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYGNSTLKCDYINVPTTVFTPMEYGSCGLPEERAVELYGLENIEVYHSLFWPLEFTVANRDNNKCYSKIIVNKLDNERVIGFHYLGPNAGEVTQGFGAAMKCGITKEQLDGTIGIHPTCAEIFTTLQVTKSSGGDIKQAGC 606          

Query:  160 FSKTTCPFC--YKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL--------DERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLD-KNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            + K++ P      +K   K+  ++   VE++L+  G+  Q++L  +T Q+TVPNVF+   H+GGCD   +A  +G +Q+LL        +++ Y+YDL+VIGGGSGGLA SKEAAN G KV VLDFV+PTP+GTTWGLGGTCVNVGCIPKKLMHQ+ALL  + +DAR +GW   E+V+H+W+ M   + N+I SLNWGYR +L++K V+Y+NAY  F++ H IK T+K   E   T+  F++ATGERPRY +IPGD+EY ITSDDLFSL YCPGKTLVIGASYVALEC GFLA LGL VTVMVRSI LRGFDQ MAN+ G +MEEHGV FI + VP KI  +E GSPG+ +V     +     +  +NTVL A+GR+ CT+RIGL+   + ++ KNG++ VN+EEQ+ V +IYAIGDI+    +LTPVAIQAGK L+RRL+G   +  DY+NVPTTVFTP+EYGS GL EE A+  YG E+IEV+H  F PLE+TVA+R +N CY K+I NK DN RV+GFH L PNAGE+TQG+  AM+ G TK   D TIGIHPTC+E FTTL +TK+SG D  Q+GC
Sbjct:    3 YMKSSSPLSSFVMVKDLFKELKVECNVVELDLIEEGTNYQEMLLELTGQKTVPNVFINKKHVGGCDKTMQAHRDGSLQRLLGGQTEENQEDQTYDYDLIVIGGGSGGLACSKEAANLGKKVMVLDFVEPTPKGTTWGLGGTCVNVGCIPKKLMHQTALLGTALQDARKFGWEFDESVKHNWETMKTAVNNYIGSLNWGYRVALKDKNVNYVNAYAEFVEPHKIKATNKRKKETFYTAAKFVLATGERPRYLDIPGDREYCITSDDLFSLPYCPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGDHMEEHGVKFIRKFVPVKIEELEAGSPGRLKVTAKSTETDEIIEGEYNTVLIAVGRNACTERIGLDKAGVRVNPKNGKIPVNDEEQTNVPHIYAIGDILEGKWELTPVAIQAGKLLARRLYGNSTLKCDYINVPTTVFTPMEYGSCGLPEERAVELYGLENIEVYHSLFWPLEFTVANRDNNKCYSKIIVNKLDNERVIGFHYLGPNAGEVTQGFGAAMKCGITKEQLDGTIGIHPTCAEIFTTLQVTKSSGGDIKQAGC 582          

Query:  406 QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDK-NGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +++YDLVVIGGGSGGLA SKEAA  G KVAVLD+V P+ +GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +DA+ YGW +  TV H W  M E +QN+++SLNWG+R  L++K V Y+N  G  +D+HTI+   K   E I+T+ N ++ATG RP+YP N+PG  E+GITSDD+F L   PGKTLV+GASYVALECAGFL  +GL  TVMVR+I LRGFDQQMA  +  ++E +G  F  + VPT++   E+ S G  +V     +   E+ D F+++L+A+GR P T  +GL+ + + + K  G++IV  +E S++ NIYA GDI     +LTP AI+AG+ L+ RL G    L +Y NV TTVFTPLEYG +GL+EE+A  ++GK+ IEV+H  +KPLE+TVA R  + CY K+IC ++ + +++G H L PNAGE+ QG+++A++ GAT R    T+GIHPT +E    +NITK SG DP  +GC
Sbjct:   27 KHDYDLVVIGGGSGGLACSKEAAQLGQKVAVLDYVDPSAKGTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDAQRYGWQISGTVSHDWATMAEAVQNYVKSLNWGHRVQLQDKKVTYLNLKGTLVDKHTIRGLSKAGKETILTAKNIVLATGGRPKYPSNVPGAMEHGITSDDIFWLKKSPGKTLVVGASYVALECAGFLTGIGLDTTVMVRTIALRGFDQQMAGLVTDHLESYGTRFEWKSVPTRV---EKLSSGALKVTWTNTQTGCEHSDTFDSLLWAVGRAPETKALGLDKLGVQISKETGKIIVGPDESSSLPNIYAFGDIGEGRPELTPTAIKAGRLLAHRLAGRSSELMNYDNVATTVFTPLEYGCVGLSEEEAEKRHGKDGIEVYHAFYKPLEFTVAQRDSSQCYIKVICERAGHQKILGLHFLGPNAGEVLQGFSLALQCGATYRQLMQTVGIHPTSAEELVKINITKRSGLDPTVTGC 512          

Query:  406 QYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYP-NIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDK-NGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            +++YDLVVIGGGSGGLA SKE                   GT WGLGGTCVNVGCIPKKLMHQ+ALL  + +DA+ YGW +  TV H W  M E +QN+++SLNWG+R  L++K V Y+N  G  +D+HTI+   K   E I+T+ N ++ATG RP+YP N+PG  E+GIT+                  S VALECAGFL  +GL  TVMVR+I LRGFDQQMA  +  ++E +G  F  + VPT++   E+ S G  +V     +   E+ D F+++L+A+GR P T  +GL+ + + + K  G++IV  +E S++ NIYA GDI     +LTP AI+AG+ L+ RL G    L +Y NV TTVFTPLEYG +GL+EE+A  ++GK+ IEV+H  +KPLE+TVA R  + CY K+IC ++ + +++G H L PNAGE+ QG+++A++ GAT R    T+GIHPT +E    +NITK SG DP  +GC
Sbjct:    4 KHDYDLVVIGGGSGGLACSKE-------------------GTKWGLGGTCVNVGCIPKKLMHQAALLGTAVKDAQRYGWQISGTVSHDWATMAEAVQNYVKSLNWGHRVQLQDKKVTYLNLKGTLVDKHTIRGLSKAGKETILTAKNIVLATGGRPKYPSNVPGAMEHGITT---------------CSHSDVALECAGFLTGIGLDTTVMVRTIALRGFDQQMAGLVTDHLESYGTRFEWKSVPTRV---EKLSSGALKVTWTNTQTGCEHSDTFDSLLWAVGRAPETKALGLDKLGVQISKETGKIIVGPDESSSLPNIYAFGDIGEGRPELTPTAIKAGRLLAHRLAGRSSELMNYDNVATTVFTPLEYGCVGLSEEEAEKRHGKDGIEVYHAFYKPLEFTVAQRDSSQCYIKVICERAGHQKILGLHFLGPNAGEVLQGFSLALQCGATYRQLMQTVGIHPTSAEELVKINITKRSGLDPTVTGC 455          

Query:  412 EYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFID--EHTIKTTDKYNNERIITSNNFIIATGERPRY---PNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSI-FLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEG--------SPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLF-GGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
             +D +VIGGGSGGLA ++ AA  GA  AV++  K         LGGTCVNVGC+PKK+M  +A+      D   YG+    +V  SW+ +  +   +I  LN  YR +L    V +I  Y  F D  E T++      N +  T+ + +I+TG +P       +PG    GI SD  F L   P +++++GA Y+A+E AG L++LG K ++++R    LR FD  ++    K ++ +G+D         +   E+G         P K         +K    +  + +L+AIGR P T  + +  + +D D  G +IV++ + +T S IYA+GD+  + L LTPVAI AG+ L+ RLF G +    DY  +PT VF+    G++GL EE+A+   GKE+++++  +F P+   +  R  + C  KL+C   +  +VVG H+      E+ QG+A+A++MGATK DFD T+ IHPT SE F T+
Sbjct:   36 RFDFLVIGGGSGGLAGARRAAELGANAAVIESHK---------LGGTCVNVGCVPKKVMWNAAVHAEYLHDHCDYGFETG-SVRFSWEALKAKRDAYIAHLNRIYRNNLDKAKVTFIQGYARFTDDAEPTVEV-----NGKKYTAPHILISTGGQPSVLSDEEVPG-ASLGINSDGFFELETLPKRSVIVGAGYIAVEMAGILSTLGSKTSLIIRQTGVLRNFDALISANCTKEIQNNGIDLWKNSQVKSVCKTEKGLEVTIVTKDPDKTN------DEKISVIEEVDCLLWAIGRQPNTAGLNIGAMGVDTDDRGHIIVDDFQNTTRSGIYAVGDVCGKAL-LTPVAIAAGRKLAHRLFEGKKDSKLDYSCIPTVVFSHPPIGTVGLTEEEAVKTKGKENVKIYKTSFTPMYHAITRR-KSQCIMKLVCVGKEE-KVVGLHMQGLGCDEMLQGFAVAIKMGATKEDFDKTVAIHPTSSEEFVTM 495          

Query:   91 MPPISTALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            MPPISTALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGL EEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC
Sbjct:    1 MPPISTALEEWIRKIINSSVLIIFSKTTCPFCYKIKKSLKDANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLLDERQYEYDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLTEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 592          

Query:  415 YDLVVIGGGSGGLAASKEAANFGAKVAVLDFVKPTPQGTTWGLGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNV----PETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVRSIFLRGFDQQMANKIGKYME-EHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKT--EYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVN-------EEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASGADPAQSGC 1866
            YDLVV+GGGSGGLA +KEAA FG +VAVLD+V P+ +GT+WGLGGTCVNVGCIPKKLMH  A ++   E A   GWN     P+++   W  M   +QN+++SLNWG+R SLR   V+YINA   F D  TI  TD    E+ I + NF+IA G RPRYP+IPG K+YGITSDDLF L   PGKTLV+G SYVALECAGFL + G   TVMVRSI LRGFD+QMA  + ++ME E  + FI    P  +I  E+G    K     Y K+K   E  D ++T+LFAIGRDPCT  + L  V + +D+  + I +       + E++T  NIYAIGD++  G++LTPVAI+AGK L+RRLF  E    +Y  +PTTVFTPLEY  +G+ EE+AI + G ++ EV+H  FKPLE  ++      CY K+IC+   + RVVG H+L  NAGE+ QG+A A++ G T +   +T+GIHPT +E    ++ITK S  DP  +GC
Sbjct:   35 YDLVVVGGGSGGLACAKEAALFGKQVAVLDYVSPSERGTSWGLGGTCVNVGCIPKKLMHHIAQMRDVIESAHDAGWNQINAKPQSLIIDWPIMASRVQNYVKSLNWGHRVSLRENKVEYINAKAKFKDAQTITATDSKGVEKEIKAKNFVIAVGGRPRYPDIPGAKQYGITSDDLFWLKKSPGKTLVVGGSYVALECAGFLHAFGCDTTVMVRSIPLRGFDRQMAEMVAEHMEKERKIKFIYGAEPVSVIEAEQGKFRVK-----YKKEKNPGEMSDVYDTILFAIGRDPCTSDLNLSVVNVSVDEGTKKITSGSKSNECDLEKTTAPNIYAIGDVLKDGVELTPVAIKAGKLLARRLFNNETGQMNYNMIPTTVFTPLEYACVGMTEEEAINRLGDKNTEVYHCFFKPLE-IISMGLQRPCYMKMICDIGHSERVVGLHILGMNAGEVLQGFAAAIKEGITHKQLSNTVGIHPTSAEEVVKIHITKRSHVDPHLTGC 526          

Query:  541 LGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVPETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATGERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVMVR-SIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKDKTEYKDWFNTV------LFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGE-HILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYGKLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTL 1821
            +GGTCVNVGC+PKK+M+ +A+++    D ++YG+ +      +W+ + ++  N+I++LN  Y ++L+   V ++          T+       N +  T+++ +IATG RP  P+IPG  E GITSD  F L   P KT+++G  Y+ +E AG L+SLG +V ++ R  + LR FD+ +   + + +   GV    +    +++      PG  E+    IK+ T   +  NT+      ++A+GR P T  + L+ + I  DK+G + V++ + ++V   YA+GD+  + L LTPVAI AG+ LS RLF  + +   DY N+PT +F+    G IG+ E++A+ KYG   ++++   FKPL + V  R +  C  KL+C   D  +++G H+      E+ QG+++A+++GATK  FDDT+ IHPT +E   T+
Sbjct:   40 MGGTCVNVGCVPKKIMYNTAMIREILRDVKNYGFKISYD-SFNWEIIKQKRDNYIKNLNNIYESNLKQNSVKFVYGEAVTNSNKTVSV-----NNKSYTADHILIATGGRPIIPDIPG-AELGITSDGFFELKALPKKTVIVGVGYIGIELAGILSSLGSEVILIARGDVVLRNFDKIIQTSVEENLHLSGVKIFYK-TDVEMVEYSIMDPGVLEI---SIKNNTN--ESVNTISNVDCLIWAVGRTPNTQTLNLDKLGIKTDKSGHISVDDCQNTSVPGFYAVGDVCGKAL-LTPVAIAAGRRLSDRLFNDQVNSKLDYTNIPTVIFSHPPCGVIGMTEQEAVDKYGSVKVKIYRTFFKPLYFAVTERKEK-CQMKLVCLLPDE-KIIGLHMCGMGCDEMLQGFSVAIKLGATKAQFDDTVAIHPTSAEELVTM 458          

Query:  541 LGGTCVNVGCIPKKLMHQSALLKHSCEDARSYGWNVP-ETVEHSWDNMVEEIQNHIQSLNWGYRTSLRNKGVDYINAYGAFIDEHTIKTTDKYNNERIITSNNFIIATG-ERPRYPNIPGDKEYGITSDDLFSLSYCPGKTLVIGASYVALECAGFLASLGLKVTVM--VRSIFLRGFDQQMANKIGKYMEEHGVDFITECVPTKIIPMEEGSPGKKEVFGCYIKD-KTEYKDWFNTVLFAIGRDPCTDRIGLENVKIDLDKNGRVIVNEEEQSTVSNIYAIGDIISRGLQLTPVAIQAGKNLSRRLFGGEHILTDYVNVPTTVFTPLEYGSIGLAEEDAIGKYGKESIEVFHQNFKPLEWTVAHRGDNDCYG--KLICNKSDNMRVVGFHVLSPNAGEITQGYAIAMRMGATKRDFDDTIGIHPTCSETFTTLNITKASG 1842
            LGGTC+NVGCIP K +  ++   H  +        +    V  + + M+      +  L  G +   ++  V ++   G+    + +  T+   N+  +++ N +IATG E   +P+I  D+E  ++S    SL   P K +VIGA  + +E     + LG +VT++  +  +   G D +++  I K + + G++F    + TK+   ++   GK  V     KD K+E  D  +T+L  IGR P T  + L +V +  D  GR+ VN + Q+ V NIYAIGD+I+ G  L   A   G  +      G  +  DY+ VP+ ++T  E   +G +EE       KE    +     PL      + ++D  G  K+I +K D  R++G +++   AGE+    A+AM  GA+  D       HPT +E F   N+    G
Sbjct:   12 LGGTCLNVGCIPSKALLNNSHYYHMAKSNELAARGIDCSGVSLNLEKMMSVKNKAVSGLTGGIKMLFKSNKVTHMEGVGSITGTNEVTVTNNSGNKEKVSTKNILIATGSEVTPFPDIEIDEESIVSSTGALSLKKVPEKMIVIGAGVIGVELGSVWSRLGAQVTLVEFLGHVGGMGIDMEISKSIQKILTKQGLNFK---LNTKVTGAQK-QGGKILVNISGTKDNKSETIDC-DTLLVCIGRRPFTGNLNLSSVGLSTDDKGRIPVNNKFQTAVPNIYAIGDVIA-GPMLAHKAEDEGI-ICVEGMCGSSVHIDYLCVPSVIYTHPEVAWVGRSEEQC-----KEEKIPYKIGKFPLVANSRAKTNDDTDGMVKVIAHK-DTDRLLGAYIVGSVAGELINEAALAMEYGASCEDIARVCHAHPTVAEAFREANLAAYCG 439          

Query:  118 EWIRKIINSSVLIIFSKTTCPFCYKIKKSLKD------ANIKYAAVEINLLATGSEIQDILYLITNQRTVPNVFVRGTHIGGCDDAHKALAEGRIQKLL 396
            E++ + I++  +++FSK+ CP+C   K  L           +Y  VE+      ++IQD L  IT  RTVP VFV    IGG  D  K     +++ LL
Sbjct:    4 EFVNEKISTKKVVVFSKSFCPYCTLAKNVLNKYIGTSIPTDQYEVVELENDPNCNKIQDYLSEITGARTVPRVFVNSKFIGGGTDVEKLDKMNQLEPLL 102