cAMP-dependent protein kinase catalytic subunit

Overview
NamecAMP-dependent protein kinase catalytic subunit
Smed IDSMED30025257
Length (bp)1189
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of cAMP-dependent protein kinase catalytic subunit (SMED30025257) t-SNE clustered cells

Violin plots show distribution of expression levels for cAMP-dependent protein kinase catalytic subunit (SMED30025257) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of cAMP-dependent protein kinase catalytic subunit (SMED30025257) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for cAMP-dependent protein kinase catalytic subunit (SMED30025257) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30025257

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
neuronSMED30025257SMESG000048614.1 dd_Smed_v4_2413_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30025257SMESG000048614.1 dd_Smed_v4_2413_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
whole organism asexual adult single-cell RNA-sequencing evidence
headSMED30025257 OX_Smed_1.0.01272ox_Smed_v2PMID:24238224
Kao et al., 2013
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30025257SMESG000048614.1 dd_Smed_v4_2413_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380])

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380])

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380])

HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0
Identity = 279/341 (81.82%), Postives = 314/341 (92.08%), Query Frame = 1
Query:  106 GDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             + +DVK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    3 SNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380])

HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0
Identity = 279/341 (81.82%), Postives = 314/341 (92.08%), Query Frame = 1
Query:  106 GDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             + +DVK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    3 SNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381])

HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0
Identity = 278/351 (79.20%), Postives = 314/351 (89.46%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKG   + VK FL  AK+DFL+KWE P+QN A L+DF+R KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W  IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC+KEF EF
Sbjct:    1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 579.711 bits (1493), Expect = 0.000e+0
Identity = 278/340 (81.76%), Postives = 320/340 (94.12%), Query Frame = 1
Query:  109 DPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            + A +K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W  IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct:   20 NSASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 359          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0
Identity = 278/336 (82.74%), Postives = 318/336 (94.64%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            VK FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W  IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct:   35 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 370          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0
Identity = 277/336 (82.44%), Postives = 318/336 (94.64%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W  IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct:   46 IKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 381          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0
Identity = 280/341 (82.11%), Postives = 320/341 (93.84%), Query Frame = 1
Query:  109 DPA-DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            DP  D K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W  IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct:   48 DPVEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 388          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137])

HSP 1 Score: 577.785 bits (1488), Expect = 0.000e+0
Identity = 278/336 (82.74%), Postives = 318/336 (94.64%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            VK FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W  IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct:    8 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495)

HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0
Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query:   67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             NN  T+    KK D A+ VK FLE AK++F +KW +   NTA LDDF+R+KTLGTGSFGRVM+VQHK  KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W  I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct:    2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852)

HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0
Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query:   67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             NN  T+    KK D A+ VK FLE AK++F +KW +   NTA LDDF+R+KTLGTGSFGRVM+VQHK  KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W  I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct:    2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851)

HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0
Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query:   67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             NN  T+    KK D A+ VK FLE AK++F +KW +   NTA LDDF+R+KTLGTGSFGRVM+VQHK  KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W  I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct:    2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529)

HSP 1 Score: 347.051 bits (889), Expect = 1.053e-115
Identity = 164/299 (54.85%), Postives = 223/299 (74.58%), Query Frame = 1
Query:  196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
            LDD+  +KT+GTG+FGRV L + + ++ Y AMKIL   +V++LKQ+EH  NE+ IL+ I  PF++ LE+  +D+SNLYM+ ++V GGE+F++LR  G+F+   + FYA+++V   EYLH L++VYRDLKPEN+LI++ G+LK+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM  GYPPF+ +QP  IYEKI+SGK+ +  H     KDL++ LL  D TKR GN+KNG +D+K H+WF    W ++Y K+L  P  P     GD  NFDDY E+  + A
Sbjct:  188 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPA 486          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528)

HSP 1 Score: 347.051 bits (889), Expect = 1.044e-114
Identity = 164/299 (54.85%), Postives = 223/299 (74.58%), Query Frame = 1
Query:  196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
            LDD+  +KT+GTG+FGRV L + + ++ Y AMKIL   +V++LKQ+EH  NE+ IL+ I  PF++ LE+  +D+SNLYM+ ++V GGE+F++LR  G+F+   + FYA+++V   EYLH L++VYRDLKPEN+LI++ G+LK+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM  GYPPF+ +QP  IYEKI+SGK+ +  H     KDL++ LL  D TKR GN+KNG +D+K H+WF    W ++Y K+L  P  P     GD  NFDDY E+  + A
Sbjct:  271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPA 569          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208])

HSP 1 Score: 576.63 bits (1485), Expect = 0.000e+0
Identity = 278/351 (79.20%), Postives = 320/351 (91.17%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   PA K+G+  + VK FL  AK+DFL KWE P+QNTACL+DFDR+KTLGTGSFGRVMLV+H++   +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DN+NLYMV+++V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWF+TT+W  IY++ +++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct:    1 MGNTPAAKRGNEMESVKEFLAFAKEDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIRVSFTEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4])

HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0
Identity = 281/351 (80.06%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKG+  + VK FL  AK+DFL KWE P Q+T CLDDFDR KTLGTGSFGRV+LV+HK +  YYAMK+LDKQKVVKLKQVEHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIKNHKWFATT+W  IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEF+EF
Sbjct:    1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6])

HSP 1 Score: 567 bits (1460), Expect = 0.000e+0
Identity = 281/352 (79.83%), Postives = 318/352 (90.34%), Query Frame = 1
Query:   79 MTTEPATK-KGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   P  K KG+  + VK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK++  ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE  F+DN+NLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+W  IY+K++++PF PKCKG GD SNFDDY+EE +R++ TEKC KEFAEF
Sbjct:    1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIRVSITEKCGKEFAEF 352          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351])

HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0
Identity = 261/336 (77.68%), Postives = 307/336 (91.37%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K  L  AK+DFL KWE   ++TACLDDFD++KTLGTGSFGRVMLV+HK+++ Y+AMKILDK KVVKLKQ+EHTLNEK+ILQA++FPFLV LE  F+DNSNLYMV+ ++ GGEMFSHLRRIGRFSE +ARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIKNH+WFA+T+W  IY+K++D+P  PKC+G GD SNFD+Y+EE +R++ +E+CSKEF +F
Sbjct:   60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351])

HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0
Identity = 261/336 (77.68%), Postives = 307/336 (91.37%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K  L  AK+DFL KWE   ++TACLDDFD++KTLGTGSFGRVMLV+HK+++ Y+AMKILDK KVVKLKQ+EHTLNEK+ILQA++FPFLV LE  F+DNSNLYMV+ ++ GGEMFSHLRRIGRFSE +ARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIKNH+WFA+T+W  IY+K++D+P  PKC+G GD SNFD+Y+EE +R++ +E+CSKEF +F
Sbjct:   60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053])

HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0
Identity = 283/351 (80.63%), Postives = 318/351 (90.60%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKG+  + VK FL  AK+DFL KWE P QNTA LDDF+R+KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIKNHKWFATT+W  IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFA+F
Sbjct:    1 MGNAATAKKGNEIESVKEFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSLTEKCAKEFADF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 572.778 bits (1475), Expect = 0.000e+0
Identity = 278/345 (80.58%), Postives = 316/345 (91.59%), Query Frame = 1
Query:   94 ATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            A K G+   VK FL  AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N  ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W  +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct:    7 AKKGGEIESVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0
Identity = 276/354 (77.97%), Postives = 318/354 (89.83%), Query Frame = 1
Query:   67 SNNLMTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            S  +     ++  G   ++K FL  AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N  ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W  +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct:    4 SVRIAICATSSNAGLCKNMKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 357          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0
Identity = 278/359 (77.44%), Postives = 322/359 (89.69%), Query Frame = 1
Query:   58 YKHSNNLMTTEPAT--KKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K + + ++  P    ++G    VK FL  AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N  ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W  +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct:   10 WKLATSQLSPSPPNLDREGQERYVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 368          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 275/336 (81.85%), Postives = 312/336 (92.86%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            VK FL  AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N  ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W  +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct:    2 VKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592])

HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0
Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 281/337 (83.38%), Postives = 312/337 (92.58%), Query Frame = 1
Query:  118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            DVK FL  AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF EF
Sbjct:    7 DVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 343          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0
Identity = 274/348 (78.74%), Postives = 308/348 (88.51%), Query Frame = 1
Query:   85 TEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            T  A K  +   VK FL  AK+DFL KWE P  + A L+DF+R KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W  IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct:    4 TAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0
Identity = 270/336 (80.36%), Postives = 304/336 (90.48%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K FL  AK+DFL KWE P  + A L+DF+R KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W  IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct:   63 MKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 398          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594])

HSP 1 Score: 553.132 bits (1424), Expect = 0.000e+0
Identity = 271/337 (80.42%), Postives = 305/337 (90.50%), Query Frame = 1
Query:  118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +VK FL  AK+DFL KWE P  + A L+DF+R KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W  IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct:    2 NVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 338          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P05132|KAPCA_MOUSE (cAMP-dependent protein kinase catalytic subunit alpha OS=Mus musculus OX=10090 GN=Prkaca PE=1 SV=3)

HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0
Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P27791|KAPCA_RAT (cAMP-dependent protein kinase catalytic subunit alpha OS=Rattus norvegicus OX=10116 GN=Prkaca PE=1 SV=2)

HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0
Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P25321|KAPCA_CRIGR (cAMP-dependent protein kinase catalytic subunit alpha OS=Cricetulus griseus OX=10029 GN=PRKACA PE=1 SV=2)

HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0
Identity = 284/351 (80.91%), Postives = 316/351 (90.03%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK++FL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P17612|KAPCA_HUMAN (cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2)

HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0
Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|Q9MZD9|KAPCA_SHEEP (cAMP-dependent protein kinase catalytic subunit alpha OS=Ovis aries OX=9940 GN=PRKACA PE=1 SV=3)

HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0
Identity = 282/351 (80.34%), Postives = 316/351 (90.03%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG   + VK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+H +  ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++PF PK KG GD SNFDDYEEE +R++  EKC KEF+EF
Sbjct:    1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A0X3NYD4 (cAMP-dependent protein kinase catalytic subunit alpha OS=Schistocephalus solidus OX=70667 GN=KAPCA PE=3 SV=1)

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 316/350 (90.29%), Postives = 336/350 (96.00%), Query Frame = 1
Query:   79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A+K+G+PADVKAFL+DAKKDFLEKWEKPSQNTACLDDFDR+KTLGTGSFGRVMLVQHK  KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV LE+HF+DNSNLYMVLEFVNGGEMFSHLR+IGRFSE HARFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF+ADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGV+DIKNHKWFA T+WF+IYK+EL++PF PKCKG GDASNFDDYEEEPLRIATTEKC K+FAEF
Sbjct:    1 MGNAAASKRGEPADVKAFLDDAKKDFLEKWEKPSQNTACLDDFDRLKTLGTGSFGRVMLVQHKAKKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVKLEYHFKDNSNLYMVLEFVNGGEMFSHLRKIGRFSEHHARFYASQVVLAFEYLHHLELVYRDLKPENILIDQQGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFYADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVSDIKNHKWFAPTDWFSIYKRELEAPFMPKCKGPGDASNFDDYEEEPLRIATTEKCVKDFAEF 350          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: C7DPD5 (Serine/threonine kinase; cAMP-dependent protein kinase catalytic subunit OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 635.18 bits (1637), Expect = 0.000e+0
Identity = 311/350 (88.86%), Postives = 336/350 (96.00%), Query Frame = 1
Query:   79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct:    1 MGNAQAAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JVC2 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma haematobium OX=6185 PE=2 SV=1)

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 309/350 (88.29%), Postives = 335/350 (95.71%), Query Frame = 1
Query:   79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMK LDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPEN+LIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct:    1 MGNAQAAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKTLDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENVLIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JWR5 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma japonicum OX=6182 GN=EWB00_007721 PE=2 SV=1)

HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0
Identity = 310/350 (88.57%), Postives = 335/350 (95.71%), Query Frame = 1
Query:   79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct:    1 MGNAQTAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A5J4NMV3 (Protein kinase A OS=Paragonimus westermani OX=34504 GN=DEA37_0002990 PE=3 SV=1)

HSP 1 Score: 627.091 bits (1616), Expect = 0.000e+0
Identity = 309/350 (88.29%), Postives = 332/350 (94.86%), Query Frame = 1
Query:   79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M     TKKGDPADVKAFLE+AKK+FLE+WEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFS+LRR+GRF+E HARFYA QVVL FEYLH+LELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWF+TT+W   YK+ELD+PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct:    1 MGNAQTTKKGDPADVKAFLEEAKKEFLERWEKPTQNTATLDAFDRIKTLGTGSFGRVMLVQHKTSKNYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSYLRRVGRFNECHARFYAGQVVLAFEYLHYLELVYRDLKPENILIDQFGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFSTTDWIATYKRELDTPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308])

HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0
Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG+  + VK FL  AK+DFL KWE P Q+T CLDDF+R+KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++P  PKC+G GD SNFDDYEEE +RI+ TEKC+KEF EF
Sbjct:    1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacab (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103023241])

HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0
Identity = 275/351 (78.35%), Postives = 316/351 (90.03%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   PA K+G+  + V+ FL  A++DFL KWE P+QNTA LD FD +KTLGTGSFGRVMLV+H++N  +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPI IYEKIVSGKVRFPSHF+SDLK+LLRNLLQVDLTKR+GNLKNGVNDIK HKWF+TT+W  IY++ +++PF PKC+G GD SNFDDYEEE +R++ TEKC KEFAEF
Sbjct:    1 MGNTPAAKRGNEMESVREFLALAREDFLRKWETPAQNTASLDQFDLLKTLGTGSFGRVMLVRHRENGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEYSFKDNSNLYMVMEYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIHIYEKIVSGKVRFPSHFSSDLKELLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCGKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000056663.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308])

HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0
Identity = 277/336 (82.44%), Postives = 310/336 (92.26%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +K FL  AK+DFL KWE P Q+T CLDDF+R+KTLGTGSFGRVMLV+HK  + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W  IY++++++P  PKC+G GD SNFDDYEEE +RI+ TEKC+KEF EF
Sbjct:   60 MKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 395          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112])

HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0
Identity = 278/351 (79.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M    A KKG+  + VK FL  AK+DFL KWE P Q+T  LDDF+R+KTLGTGSFGRVMLV+HK  + ++AMK+LDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIKNHKWFATT+W  IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEF EF
Sbjct:    1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFTEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 277/338 (81.95%), Postives = 311/338 (92.01%), Query Frame = 1
Query:  115 ADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             DVK FL  AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+   ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE  F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W  IY++++++PF PKCKG GD SNFDDYEEE +R++ TEKC KEFAEF
Sbjct:   82 VDVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 419          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 497.278 bits (1279), Expect = 1.501e-178
Identity = 227/265 (85.66%), Postives = 253/265 (95.47%), Query Frame = 1
Query:  334 EHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            EHTLNEKRILQAI+FPFLV LE+ F+DNSNLYMVLE+V GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF+TT+W  IY++++++PF PKCKG GDASNFDDYEEE +RI++TEKC+KEFA+F
Sbjct:   24 EHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISSTEKCAKEFADF 288          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 254.988 bits (650), Expect = 1.010e-84
Identity = 132/168 (78.57%), Postives = 152/168 (90.48%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKV 624
            VK FL  AK+DFL+KWE P QNT+CLDDF+R+KTLGTGSFGRVMLV+HK    Y+AMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV LE+ ++DNSNLYMVLE+V GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++V
Sbjct:   16 VKEFLAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 249.595 bits (636), Expect = 1.924e-80
Identity = 129/295 (43.73%), Postives = 188/295 (63.73%), Query Frame = 1
Query:  205 FDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEE 1077
             D + TLG G FGRV LV+ K +   +A+K L K+ VV+ +Q EH  +EKRILQ  + PF+V     FRD   +++++E   GGE++S LR  G F E  ARF  + VV    YLH   ++YRDLKPEN+L+D  GY+K+ DFGFAK++  GR  WT CGTPEY+ PE+I+++G+++  D WALGVL+YE+ AG PPF    P++ Y  I+ G  +V FP+      +D++R L + + ++R GN K+GV D++ HKWF   +W ++   +L SP   +  G  D  NFD + E+
Sbjct:   34 MDVIATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPED 328          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 243.817 bits (621), Expect = 4.108e-77
Identity = 129/315 (40.95%), Postives = 192/315 (60.95%), Query Frame = 1
Query:  175 PSQN-TACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRIL-QAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD-YEEEPLRIATTE 1101
            PS N  A   DFD +  LG GSFG+V+L +HK +  +YA+K++ K  +++ K+ +H + E+ +L + +  PFLV L + F+    LY V+++VNGGE+F HL+R G F ES A+FYA+++     YLH L +VYRDLKPENIL+D  G++ +TDFG  K        T T CGTPEYLAPE++    Y++ VDWW LG ++YEM  G PPF++    Q+YE I+   ++     T+    +L  LL  D  +R G   + + +IKNH +F+T  W ++  K + SP+ P   G  D  NFD  +  EPL ++  +
Sbjct:   81 PSANLQAKPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSD-ILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMSMAQ 394          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 239.195 bits (609), Expect = 9.728e-75
Identity = 126/302 (41.72%), Postives = 185/302 (61.26%), Query Frame = 1
Query:  172 KPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLH-HLELVYRDLKPENILIDQTGYLKVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD 1065
            KP ++   +++FD +K LG G+FG+V+LV+ K    YYAMKIL K+ +V   +V HTL E R+LQ    PFL  L++ F+ +  L  V+E+VNGGE+F HL R   FSE   RFY +++V   +YLH    +VYRDLK EN+++D+ G++K+ DFG  K     G T  T CGTPEYLAPE++    Y +AVDWW LGV++YEM  G  PF+     +++E I+   +RFP   ++D + LL  LL+ D  +R G   +   +I  H +FA   W ++Y +++  PF P+     D   FD+
Sbjct:  140 KP-KSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDE 440          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124])

HSP 1 Score: 326.25 bits (835), Expect = 4.133e-110
Identity = 161/303 (53.14%), Postives = 221/303 (72.94%), Query Frame = 1
Query:  178 SQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPK-CKGAGDASNFDDYEEEPL 1083
            S+    L DF  ++TLGTGSFGRV LV+   N  YYA+K+L KQ+VVK+KQVEHT +E+R+L+ +  PFL+ +   F+D  N++MV++++ GGE+FS LR+  RF    A+FYA++V+L  EYLH   ++YRDLKPENIL+D+ G++K+TDFGFAK V+  TWTLCGTP+Y+APE+I +K YNK+VDWW+LGVLIYEM AGY PF+   P++ YEKI+ GKV +P +F  D+ DLL  L+  DLT+R GNL++G  DIK H WF+   W  +  K++++P+ P    G GD S FD Y EE L
Sbjct:   61 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQL 363          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 313.153 bits (801), Expect = 9.311e-105
Identity = 151/322 (46.89%), Postives = 224/322 (69.57%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKC-KGAGDASNFDDYEEEPL 1083
            V  + E+  K F+ +  + +     L DF  ++TLGTGSFGRV L++ + N  YYAMK+L K+ VV+LKQVEHT +E+ +L  +  PF++ +   F+D   ++M+++++ GGE+FS LR+  RF    A+FYA++V L  EYLH  +++YRDLKPENIL+D+ G++K+TDFGFAK V   T+TLCGTP+Y+APE++ +K YNK++DWW+ G+LIYEM AGY PF+    ++ YEKI++ ++RFP  F  D+KDLL  L+  DL++R GNL+NG  D+KNH WF    W  +  + +++P+ P   +G GD S FD Y EE +
Sbjct:   60 VTYYNEEQYKQFIAQ-ARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDI 380          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649])

HSP 1 Score: 306.605 bits (784), Expect = 4.290e-102
Identity = 146/296 (49.32%), Postives = 212/296 (71.62%), Query Frame = 1
Query:  193 CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKC-KGAGDASNFDDYEEE 1077
             L DF  ++TLGTGSFGRV L++   N  +YA+K L K  +VKLKQVEHT +E+R+L  ++ PF++ +   F+D+  ++MV++++ GGE+FS LR+  RF    A+FYA++V L  EYLH  +++YRDLKPENIL+D+ G++K+TDFGFAK V   T+TLCGTP+Y+APE++ +K YNK+VDWW+ GVLIYEM AGY PF+    ++ YE I++ +++FP  F  D +DLL+ L+  DL++R GNL+NG  D+KNH WF    W  +  + +++P+ P   +G GD S FD Y EE
Sbjct:   84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609])

HSP 1 Score: 272.707 bits (696), Expect = 8.774e-86
Identity = 142/320 (44.38%), Postives = 201/320 (62.81%), Query Frame = 1
Query:  172 KPSQNTA-CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD--YEEEPLRIATTEKCSK 1113
            KPS+N    +DDFD +K +G GSFG+VM V+ K  +  YA+K + K  +V   +V HTL E+ +L  ++ PF+V L+F F+    LY VL F+NGGE+F HL++ GRF  S ARFY ++++   + LH L++VYRDLKPENIL+D  G++ + DFG  K   +   +T T CGTPEYLAPE++L  GY KAVDWW LGVL+YEM  G PP++ +   ++Y+KI+   + FP  F  D KDLL  LL  D T+R G   NG ++I+NH +F+   W  +  K    P+ P    + D SNFD+    E+P+     E  S+
Sbjct:  335 KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSE 652          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710])

HSP 1 Score: 263.462 bits (672), Expect = 2.843e-82
Identity = 138/319 (43.26%), Postives = 198/319 (62.07%), Query Frame = 1
Query:  172 KPSQNTA-CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD--YEEEPLRIATTEKCS 1110
            KPS+N    +DDFD +K +G GSFG+VM V+ K  +  YA+K L K  +V   +V HTL E+ +L  ++ PF+V L+F F+    LY+VL F+NGGE+F HL+  GRFS + +RFY ++++   + LH L+++YRDLKPENIL+D  G++ + DFG  K   +   +T T CGTPEYLAPEI+L +GY K VDWW LG+L+YEM  G PP++ +    +Y+KI+   + FP  F    KDLL  LL  D ++R G   NG ++I+NH +F    W  +  K    P+ P  K   D +NFD    +E+P+     E  S
Sbjct:  332 KPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLS 648          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62])

HSP 1 Score: 333.954 bits (855), Expect = 2.518e-113
Identity = 166/302 (54.97%), Postives = 218/302 (72.19%), Query Frame = 1
Query:  190 ACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF-TSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
              L DF+  KTLGTG+FGRV+L + ++  ++YA+KI++  +V++LKQVEH  NEK IL +I  PF+V+L +   D + LYM+LE+  GGE+F++LR  GRF+     F+ S++V   +YLH   +VYRDLKPENIL+D+ G++K+TDFGFAK V  +TWTLCGTPEYLAPEII SKG+NKAVDWWALG+LIYEM  GYPPFF D P  IYEKI+SGKV +P H   +  KDL++ LL  D T+R G++KNG  D+KNHKWF   +W  + +++L  P  PK    GD  NFDDY EE  R A
Sbjct:   13 TTLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGA 314          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7])

HSP 1 Score: 258.84 bits (660), Expect = 3.197e-80
Identity = 135/292 (46.23%), Postives = 187/292 (64.04%), Query Frame = 1
Query:  196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNF 1059
            L+D   VKTLG G FGRV LVQ   +K  +A+K L K  +V+ +Q +H ++EK+I+   N PF+V L   F+D   LYM+LE   GGE+++ LR  G F +S  RFY   V+  F+YLH   +VYRDLKPEN+L+D  GY K+ DFGFAK++  GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+L+YE+  G PPF    P++ Y  I+ G   + FP   T +   L++ L + +  +R G  K G+ DI  HKWF    W  +  ++L+SP  PK K   DASNF
Sbjct:  349 LEDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSPVDASNF 640          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2])

HSP 1 Score: 246.514 bits (628), Expect = 4.623e-78
Identity = 130/354 (36.72%), Postives = 206/354 (58.19%), Query Frame = 1
Query:   76 LMTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRIL-QAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFD-DYEEEPLRIATTEKCSKEFA 1122
            L    P   + +  D +   +DA  + ++  E  +   A   DF  +K +G GSFG+V L ++K+   +YA+K+L+K  + K  + +H + E+ +L Q +  PFLV L + F+    LY VL++VNGGE+F HL+R   F ES ARFYA+++     YLH L+++YRDLKPENIL+D  G++ +TDFG  K      G T T CGTPEYLAPE++  + Y+K+VDWW LG ++YEM  G PPF++    ++Y+ I+   +R  ++ +   + +L  LLQ D TKR G+ +    DI+ H +F +  W  +  + ++ P+ P   G  D  +FD ++  EP+  +  +     F 
Sbjct:   32 LSLDNPKNAQANDEDEQPGSDDADVEKIDLGES-NNPKAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPVPGSVGKSADSNFV 384          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521])

HSP 1 Score: 237.269 bits (604), Expect = 2.087e-74
Identity = 121/308 (39.29%), Postives = 173/308 (56.17%), Query Frame = 1
Query:  160 EKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQ----HKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFD 1062
            E+   P       + F+ +K LG G +G+V LV+    H K K +    +     +   K   HT  E+ IL+ +  PF+V L + F+    LY++LE+++GGE+F  L R G F E  A FY S++ +  E+LH   +VYRDLKPENIL+D  G++K+TDFG  K        T T CGT EY+APEI+   G+ KAVDWW+LG L+Y+M  G PPF AD   +  +KI+ GK+  P + T + KD +R LL+     R G +    N IK H +F    W ++  K+++ PF P   G  D S FD
Sbjct:   50 EETVNPKDEKVGPESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFD 357          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8])

HSP 1 Score: 231.876 bits (590), Expect = 4.690e-70
Identity = 131/297 (44.11%), Postives = 186/297 (62.63%), Query Frame = 1
Query:  151 DFLEKWEKPSQNTA--CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRV-KGR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFT 1023
            D  E+  K S+  A   L+D + V TLGTG FGRV LV        YA+K L K+ ++  +Q EH  +EKRIL   N PF+  +   F+D   +YM+LE   GGE+++ LR  G F ++ ARF  + VV GFEYLH   +VYRDLKPEN+L+D  GY+K+ DFGFAK++  GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+LI+E+  G PPF +  P++ Y  I+ G   V FP     + ++L++ L + +  +R G  K+G++DIK HK+     WF +       P T
Sbjct:  311 DVPEEERKVSKEFADLTLEDLEVVATLGTGGFGRVELVT-------YALKCLKKKHILDTRQQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKHKYVVP--WFPLAGTHRRDPRT 598          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876])

HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0
Identity = 279/351 (79.49%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKG+  + VK FL  AK+DFL KWE P Q+T CL+DFDR+KTLGTGSFGRVMLV+HK ++ Y+AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFATT+W  IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct:    1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876])

HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0
Identity = 279/354 (78.81%), Postives = 317/354 (89.55%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD----VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M      KKG+  +    VK FL  AK+DFL KWE P Q+T CL+DFDR+KTLGTGSFGRVMLV+HK ++ Y+AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID  GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFATT+W  IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct:    1 MGNAATAKKGNELESDTFVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 354          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742])

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 278/351 (79.20%), Postives = 316/351 (90.03%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   P  KKG+  + VK FL  AK+DFL+KWE P+Q TA LD F+R+KTLGTGSFGRVMLV+HK+   ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE  F+D SNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIK HKWFATT+W  IY++++++PF PKCKG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct:    1 MGNTPTAKKGNEVESVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 274/337 (81.31%), Postives = 310/337 (91.99%), Query Frame = 1
Query:  118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            DVK FL  AK+DFL+KWE P+Q TA LD F+R+KTLGTGSFGRVMLV+HK+   ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE  F+D SNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIK HKWFATT+W  IY++++++PF PKCKG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct:   41 DVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 377          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000040218.1 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964])

HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0
Identity = 274/351 (78.06%), Postives = 317/351 (90.31%), Query Frame = 1
Query:   79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   P  +KG+  + VK FL  AK+DFL+KWE PSQNTA L+ F+R+KTLGTGSFGRVMLV+H++   +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LEF F+DN+NLYMV+E+V GGEMFSHLR+IGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFA T+W  I++K++++PF PK KG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct:    1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQNTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFAATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1)

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 280/336 (83.33%), Postives = 309/336 (91.96%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            VKAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK  K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF   +W  I+KKEL++PF P  KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct:  172 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 507          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1)

HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0
Identity = 280/336 (83.33%), Postives = 309/336 (91.96%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            VKAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK  K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF   +W  I+KKEL++PF P  KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct:  295 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 630          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1)

HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0
Identity = 279/336 (83.04%), Postives = 309/336 (91.96%), Query Frame = 1
Query:  121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            +KAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK  K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID  GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF   +W  I+KKEL++PF P  KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct:  247 MKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 582          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000016651.1 (SMESG000016651.1)

HSP 1 Score: 526.168 bits (1354), Expect = 0.000e+0
Identity = 254/352 (72.16%), Postives = 308/352 (87.50%), Query Frame = 1
Query:   79 MTTEPATKKG--DPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
            M   P  K+   D + VK FLE+AKK+F +K++ P Q T  LD+F+ +KTLGTGSFGRV+L  HKK+K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI+FPFL+ L++ F+DNSNLYMVLEFVNGGEMFSHLRR+G+FSE+HA+FYASQVVL FEYLHHL+L+YRDLKPENILID  GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF+ +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + +W++ +KKEL +PF PKC+G GD SNFD+YEEE L+I+TT KC+ EF EF
Sbjct:    1 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAVKVLDKLKIVKLKQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 352          
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1)

HSP 1 Score: 483.797 bits (1244), Expect = 1.098e-171
Identity = 236/346 (68.21%), Postives = 289/346 (83.53%), Query Frame = 1
Query:   94 ATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
             +KK +  +V+ FLE+A+++F +KW+ P  N A L +F RVKTLGTG+FG V+LV   +   YYAMK+L+KQK+VK+KQVEHTLNEKRILQA+NFPFLV+L + F+DNS LY+VLE+V GGEMFSHLR+ GR+SE  A FYASQVV+ FEYLH+L++VYRDLKPENILI++ GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALG+LIYEM  GYPPF ADQPI IYEKIV GK +FP++ + D KDL+R LLQ DLTKR+GNLKNGV DIKNHKWF   ++W NIYK+++  PF P+ K  GD S FDDY+EEPL+I+  EKC+KEF +F
Sbjct:    5 TSKKENNCEVEEFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 350          
The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRKACA0.000e+080.63protein kinase cAMP-activated catalytic subunit al... [more]
PRKACA0.000e+080.63protein kinase cAMP-activated catalytic subunit al... [more]
PRKACA0.000e+081.82protein kinase cAMP-activated catalytic subunit al... [more]
PRKACA0.000e+081.82protein kinase cAMP-activated catalytic subunit al... [more]
PRKACB0.000e+079.20protein kinase cAMP-activated catalytic subunit be... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
kin-10.000e+081.76cAMP-dependent protein kinase catalytic subunit [... [more]
kin-10.000e+082.74cAMP-dependent protein kinase catalytic subunit [... [more]
kin-10.000e+082.44cAMP-dependent protein kinase catalytic subunit [... [more]
kin-10.000e+082.11cAMP-dependent protein kinase catalytic subunit [... [more]
kin-10.000e+082.74cAMP-dependent protein kinase catalytic subunit [... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Pka-C10.000e+079.72gene:FBgn0000273 transcript:FBtr0335495[more]
Pka-C10.000e+079.72gene:FBgn0000273 transcript:FBtr0079852[more]
Pka-C10.000e+079.72gene:FBgn0000273 transcript:FBtr0079851[more]
Pka-C31.053e-11554.85gene:FBgn0000489 transcript:FBtr0075529[more]
Pka-C31.044e-11454.85gene:FBgn0000489 transcript:FBtr0075528[more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkacab0.000e+079.20protein kinase, cAMP-dependent, catalytic, alpha, ... [more]
prkacbb0.000e+080.06protein kinase, cAMP-dependent, catalytic, beta b ... [more]
prkacaa0.000e+079.83protein kinase, cAMP-dependent, catalytic, alpha, ... [more]
prkacba0.000e+077.68protein kinase, cAMP-dependent, catalytic, beta a ... [more]
prkacba0.000e+077.68protein kinase, cAMP-dependent, catalytic, beta a ... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
prkacb0.000e+080.63protein kinase cAMP-activated catalytic subunit be... [more]
ints80.000e+080.58integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints80.000e+077.97integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints80.000e+077.44integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
ints80.000e+081.85integrator complex subunit 8 [Source:Xenbase;Acc:X... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Prkaca0.000e+081.20protein kinase, cAMP dependent, catalytic, alpha [... [more]
Prkaca0.000e+083.38protein kinase, cAMP dependent, catalytic, alpha [... [more]
Prkacb0.000e+078.74protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkacb0.000e+080.36protein kinase, cAMP dependent, catalytic, beta [S... [more]
Prkacb0.000e+080.42protein kinase, cAMP dependent, catalytic, beta [S... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P05132|KAPCA_MOUSE0.000e+081.20cAMP-dependent protein kinase catalytic subunit al... [more]
sp|P27791|KAPCA_RAT0.000e+081.20cAMP-dependent protein kinase catalytic subunit al... [more]
sp|P25321|KAPCA_CRIGR0.000e+080.91cAMP-dependent protein kinase catalytic subunit al... [more]
sp|P17612|KAPCA_HUMAN0.000e+080.63cAMP-dependent protein kinase catalytic subunit al... [more]
sp|Q9MZD9|KAPCA_SHEEP0.000e+080.34cAMP-dependent protein kinase catalytic subunit al... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NYD40.000e+090.29cAMP-dependent protein kinase catalytic subunit al... [more]
C7DPD50.000e+088.86Serine/threonine kinase; cAMP-dependent protein ki... [more]
D2JVC20.000e+088.29cAMP-dependent protein kinase catalytic subunit OS... [more]
D2JWR50.000e+088.57cAMP-dependent protein kinase catalytic subunit OS... [more]
A0A5J4NMV30.000e+088.29Protein kinase A OS=Paragonimus westermani OX=3450... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000050353.10.000e+080.63protein kinase cAMP-activated catalytic subunit be... [more]
prkacab0.000e+078.35cAMP-dependent protein kinase catalytic subunit al... [more]
ENSAMXT00000056663.10.000e+082.44protein kinase cAMP-activated catalytic subunit be... [more]
prkacbb0.000e+079.20cAMP-dependent protein kinase catalytic subunit be... [more]
prkacaa0.000e+081.95cAMP-dependent protein kinase catalytic subunit al... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001814.11.501e-17885.66pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gen... [more]
ENSPMAT00000004852.11.010e-8478.57pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gen... [more]
ENSPMAT00000002200.11.924e-8043.73pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 ... [more]
ENSPMAT00000006766.14.108e-7740.95pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 g... [more]
ENSPMAT00000008480.19.728e-7541.72pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
TPK24.133e-11053.14cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK19.311e-10546.89cAMP-dependent protein kinase catalytic subunit; p... [more]
TPK34.290e-10249.32cAMP-dependent protein kinase catalytic subunit; p... [more]
YPK18.774e-8644.38S/T protein kinase; phosphorylates, downregulates ... [more]
YPK22.843e-8243.26Protein kinase similar to S/T protein kinase Ypk1p... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO352282.518e-11354.97Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO384073.197e-8046.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO378004.623e-7836.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411662.087e-7439.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO383994.690e-7044.11Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000033457.10.000e+079.49cAMP-dependent protein kinase catalytic subunit be... [more]
ENSORLT00000035979.10.000e+078.81cAMP-dependent protein kinase catalytic subunit be... [more]
prkacaa0.000e+079.20cAMP-dependent protein kinase catalytic subunit al... [more]
prkacaa0.000e+081.31cAMP-dependent protein kinase catalytic subunit al... [more]
ENSORLT00000040218.10.000e+078.06cAMP-dependent protein kinase catalytic subunit al... [more]
back to top
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000038292.10.000e+083.33SMESG000038292.1[more]
SMESG000038292.10.000e+083.33SMESG000038292.1[more]
SMESG000038292.10.000e+083.04SMESG000038292.1[more]
SMESG000016651.10.000e+072.16SMESG000016651.1[more]
SMESG000000892.11.098e-17168.21SMESG000000892.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025257 ID=SMED30025257|Name=cAMP-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1189bp
ATAATCAATTTTAACATATCACTTTAGTATTATCACTTTATTTTTCTTCA
ATGAATATATAAACACTCCAACAATTTGATGACCACGGAACCAGCAACCA
AGAAAGGTGATCCTGCCGATGTTAAGGCTTTTTTGGAGGATGCGAAAAAA
GATTTTTTGGAAAAATGGGAAAAACCGAGTCAAAATACGGCTTGTCTCGA
TGACTTCGACCGGGTAAAGACTCTCGGCACTGGCTCATTTGGTCGCGTGA
TGTTGGTGCAACACAAAAAGAATAAAGATTATTATGCCATGAAAATTCTC
GACAAACAAAAAGTTGTCAAACTTAAACAAGTCGAGCACACTTTAAATGA
AAAACGAATATTGCAAGCGATCAATTTTCCTTTCCTTGTTCATTTGGAAT
TTCACTTTAGAGATAACAGCAACCTGTACATGGTTCTGGAGTTTGTCAAT
GGTGGTGAAATGTTTTCTCATCTCAGAAGAATCGGAAGATTCAGTGAGAG
TCATGCACGATTTTATGCGAGTCAAGTCGTTTTGGGTTTCGAATATCTGC
ATCATTTAGAACTCGTTTACAGAGACTTAAAACCAGAAAATATACTAATA
GATCAAACAGGATATCTCAAAGTAACAGATTTTGGTTTTGCTAAAAGAGT
AAAAGGTAGAACTTGGACTCTTTGCGGTACACCCGAATACCTGGCTCCAG
AGATTATTCTCAGTAAAGGTTATAATAAAGCAGTTGATTGGTGGGCTTTA
GGTGTCCTCATTTATGAAATGGCTGCTGGGTATCCGCCATTCTTTGCTGA
TCAACCTATTCAGATTTATGAGAAAATTGTTTCCGGAAAAGTTCGCTTCC
CATCTCATTTTACATCAGATCTTAAAGATCTATTAAGAAATCTCTTGCAA
GTCGATTTAACTAAACGATTCGGCAATCTCAAAAATGGAGTCAACGACAT
TAAGAATCACAAATGGTTTGCCACTACAGAATGGTTTAATATTTATAAAA
AAGAGTTGGATTCTCCATTTACACCCAAGTGCAAAGGTGCTGGAGATGCT
AGTAATTTTGACGATTATGAAGAAGAACCACTTCGAATAGCAACAACTGA
AAAATGTTCAAAGGAATTTGCTGAATTTTAATGAGACCTTCATTACATTG
ATACTTTGTTTGACGTATTATTATTATTATTATTATTAT
back to top

protein sequence of SMED30025257-orf-1

>SMED30025257-orf-1 ID=SMED30025257-orf-1|Name=SMED30025257-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=351bp
MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLG
TGSFGRVMLVQHKKNKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAINF
PFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQV
VLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCG
TPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKI
VSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT
EWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF
*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004691cAMP-dependent protein kinase activity
GO:0034237protein kinase A regulatory subunit binding
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0004674protein serine/threonine kinase activity
GO:0000166nucleotide binding
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0010737protein kinase A signaling
GO:0071333cellular response to glucose stimulus
GO:0006468protein phosphorylation
GO:0016310phosphorylation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR039035PKA_C-alpha
IPR000719Prot_kinase_dom
IPR000961AGC-kinase_C
IPR008271Ser/Thr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR011009Kinase-like_dom_sf
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 43..297
e-value: 1.3E-102
score: 356.8
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 44..297
e-value: 5.3E-72
score: 242.4
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 43..297
score: 49.573
IPR000961AGC-kinase, C-terminalSMARTSM00133pkinase_C_6coord: 298..350
e-value: 4.1E-7
score: 39.6
IPR000961AGC-kinase, C-terminalPROSITEPS51285AGC_KINASE_CTERcoord: 298..350
score: 11.391
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 127..317
e-value: 4.1E-129
score: 431.7
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 8..304
e-value: 4.2E-33
score: 112.3
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 40..329
e-value: 4.1E-129
score: 431.7
NoneNo IPR availablePANTHERPTHR24353CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASEcoord: 9..350
NoneNo IPR availableCDDcd14209STKc_PKAcoord: 41..330
e-value: 0.0
score: 614.798
IPR039035cAMP-dependent protein kinase catalytic subunit alphaPANTHERPTHR24353:SF82CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHAcoord: 9..350
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 49..72
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 162..174
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 32..337