cAMP-dependent protein kinase catalytic subunit
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025257 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0 Identity = 279/341 (81.82%), Postives = 314/341 (92.08%), Query Frame = 1
Query: 106 GDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+ +DVK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 3 SNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 572.007 bits (1473), Expect = 0.000e+0 Identity = 279/341 (81.82%), Postives = 314/341 (92.08%), Query Frame = 1
Query: 106 GDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+ +DVK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 3 SNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 565.844 bits (1457), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 314/351 (89.46%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKG + VK FL AK+DFL+KWE P+QN A L+DF+R KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC+KEF EF
Sbjct: 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 579.711 bits (1493), Expect = 0.000e+0 Identity = 278/340 (81.76%), Postives = 320/340 (94.12%), Query Frame = 1
Query: 109 DPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+ A +K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct: 20 NSASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 579.326 bits (1492), Expect = 0.000e+0 Identity = 278/336 (82.74%), Postives = 318/336 (94.64%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
VK FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct: 35 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 370
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 578.941 bits (1491), Expect = 0.000e+0 Identity = 277/336 (82.44%), Postives = 318/336 (94.64%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct: 46 IKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 381
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 578.556 bits (1490), Expect = 0.000e+0 Identity = 280/341 (82.11%), Postives = 320/341 (93.84%), Query Frame = 1
Query: 109 DPA-DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
DP D K FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct: 48 DPVEDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 388
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 577.785 bits (1488), Expect = 0.000e+0 Identity = 278/336 (82.74%), Postives = 318/336 (94.64%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
VK FL+ A++DF ++WE P+QNTACLDDFDR+KTLGTGSFGRVMLV+HK++ +YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV++ F F+DNSNLYMVLEF++GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LID TGYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKV+FPSHF+++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T+W IY+K++++PF PKC+G GDASNFDDYEEEPLRI+ TEKC+KEFAEF
Sbjct: 8 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495) HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0 Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query: 67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
NN T+ KK D A+ VK FLE AK++F +KW + NTA LDDF+R+KTLGTGSFGRVM+VQHK KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct: 2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852) HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0 Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query: 67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
NN T+ KK D A+ VK FLE AK++F +KW + NTA LDDF+R+KTLGTGSFGRVM+VQHK KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct: 2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851) HSP 1 Score: 570.081 bits (1468), Expect = 0.000e+0 Identity = 283/355 (79.72%), Postives = 318/355 (89.58%), Query Frame = 1
Query: 67 SNNLMTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
NN T+ KK D A+ VK FLE AK++F +KW + NTA LDDF+R+KTLGTGSFGRVM+VQHK KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI FPFLV L +HF+DNSNLYMVLE+V GGEMFSHLR++GRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWFA+T+W I++K++++PF P+CKG GD SNFDDYEEE LRI++TEKC+KEFAEF
Sbjct: 2 GNNATTS---NKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529) HSP 1 Score: 347.051 bits (889), Expect = 1.053e-115 Identity = 164/299 (54.85%), Postives = 223/299 (74.58%), Query Frame = 1
Query: 196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
LDD+ +KT+GTG+FGRV L + + ++ Y AMKIL +V++LKQ+EH NE+ IL+ I PF++ LE+ +D+SNLYM+ ++V GGE+F++LR G+F+ + FYA+++V EYLH L++VYRDLKPEN+LI++ G+LK+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM GYPPF+ +QP IYEKI+SGK+ + H KDL++ LL D TKR GN+KNG +D+K H+WF W ++Y K+L P P GD NFDDY E+ + A
Sbjct: 188 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPA 486
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528) HSP 1 Score: 347.051 bits (889), Expect = 1.044e-114 Identity = 164/299 (54.85%), Postives = 223/299 (74.58%), Query Frame = 1
Query: 196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
LDD+ +KT+GTG+FGRV L + + ++ Y AMKIL +V++LKQ+EH NE+ IL+ I PF++ LE+ +D+SNLYM+ ++V GGE+F++LR G+F+ + FYA+++V EYLH L++VYRDLKPEN+LI++ G+LK+TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKAVDWWALGVLIYEM GYPPF+ +QP IYEKI+SGK+ + H KDL++ LL D TKR GN+KNG +D+K H+WF W ++Y K+L P P GD NFDDY E+ + A
Sbjct: 271 LDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPA 569
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208]) HSP 1 Score: 576.63 bits (1485), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 320/351 (91.17%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M PA K+G+ + VK FL AK+DFL KWE P+QNTACL+DFDR+KTLGTGSFGRVMLV+H++ +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DN+NLYMV+++V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWF+TT+W IY++ +++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct: 1 MGNTPAAKRGNEMESVKEFLAFAKEDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIRVSFTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4]) HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0 Identity = 281/351 (80.06%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKG+ + VK FL AK+DFL KWE P Q+T CLDDFDR KTLGTGSFGRV+LV+HK + YYAMK+LDKQKVVKLKQVEHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIKNHKWFATT+W IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEF+EF
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6]) HSP 1 Score: 567 bits (1460), Expect = 0.000e+0 Identity = 281/352 (79.83%), Postives = 318/352 (90.34%), Query Frame = 1
Query: 79 MTTEPATK-KGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M P K KG+ + VK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK++ ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE F+DN+NLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+W IY+K++++PF PKCKG GD SNFDDY+EE +R++ TEKC KEFAEF
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIRVSITEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0 Identity = 261/336 (77.68%), Postives = 307/336 (91.37%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K L AK+DFL KWE ++TACLDDFD++KTLGTGSFGRVMLV+HK+++ Y+AMKILDK KVVKLKQ+EHTLNEK+ILQA++FPFLV LE F+DNSNLYMV+ ++ GGEMFSHLRRIGRFSE +ARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIKNH+WFA+T+W IY+K++D+P PKC+G GD SNFD+Y+EE +R++ +E+CSKEF +F
Sbjct: 60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 545.043 bits (1403), Expect = 0.000e+0 Identity = 261/336 (77.68%), Postives = 307/336 (91.37%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K L AK+DFL KWE ++TACLDDFD++KTLGTGSFGRVMLV+HK+++ Y+AMKILDK KVVKLKQ+EHTLNEK+ILQA++FPFLV LE F+DNSNLYMV+ ++ GGEMFSHLRRIGRFSE +ARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVR+PSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIKNH+WFA+T+W IY+K++D+P PKC+G GD SNFD+Y+EE +R++ +E+CSKEF +F
Sbjct: 60 MKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053]) HSP 1 Score: 578.17 bits (1489), Expect = 0.000e+0 Identity = 283/351 (80.63%), Postives = 318/351 (90.60%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKG+ + VK FL AK+DFL KWE P QNTA LDDF+R+KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIKNHKWFATT+W IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFA+F
Sbjct: 1 MGNAATAKKGNEIESVKEFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSLTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 572.778 bits (1475), Expect = 0.000e+0 Identity = 278/345 (80.58%), Postives = 316/345 (91.59%), Query Frame = 1
Query: 94 ATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
A K G+ VK FL AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct: 7 AKKGGEIESVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 276/354 (77.97%), Postives = 318/354 (89.83%), Query Frame = 1
Query: 67 SNNLMTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
S + ++ G ++K FL AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct: 4 SVRIAICATSSNAGLCKNMKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 568.54 bits (1464), Expect = 0.000e+0 Identity = 278/359 (77.44%), Postives = 322/359 (89.69%), Query Frame = 1
Query: 58 YKHSNNLMTTEPAT--KKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K + + ++ P ++G VK FL AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct: 10 WKLATSQLSPSPPNLDREGQERYVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 368
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 275/336 (81.85%), Postives = 312/336 (92.86%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
VK FL AK+DFL+KWE P+QNTA L+ F+R+KTLGTGSFGRVMLV+HK+N ++AMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV DIK HKWF+TT+W +Y+K++++PF PKCKG GD SNFDDYEEE +R++ TEKC+KEF++F
Sbjct: 2 VKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0 Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0 Identity = 281/337 (83.38%), Postives = 312/337 (92.58%), Query Frame = 1
Query: 118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
DVK FL AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF EF
Sbjct: 7 DVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 556.214 bits (1432), Expect = 0.000e+0 Identity = 274/348 (78.74%), Postives = 308/348 (88.51%), Query Frame = 1
Query: 85 TEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
T A K + VK FL AK+DFL KWE P + A L+DF+R KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct: 4 TAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 553.518 bits (1425), Expect = 0.000e+0 Identity = 270/336 (80.36%), Postives = 304/336 (90.48%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K FL AK+DFL KWE P + A L+DF+R KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct: 63 MKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 398
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 553.132 bits (1424), Expect = 0.000e+0 Identity = 271/337 (80.42%), Postives = 305/337 (90.50%), Query Frame = 1
Query: 118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+VK FL AK+DFL KWE P + A L+DF+R KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W IY++++++PF PK +G+GD SNFDDYEEE +R++ TEKC KEF EF
Sbjct: 2 NVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 338
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P05132|KAPCA_MOUSE (cAMP-dependent protein kinase catalytic subunit alpha OS=Mus musculus OX=10090 GN=Prkaca PE=1 SV=3) HSP 1 Score: 577.015 bits (1486), Expect = 0.000e+0 Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P27791|KAPCA_RAT (cAMP-dependent protein kinase catalytic subunit alpha OS=Rattus norvegicus OX=10116 GN=Prkaca PE=1 SV=2) HSP 1 Score: 575.474 bits (1482), Expect = 0.000e+0 Identity = 285/351 (81.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK++ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P25321|KAPCA_CRIGR (cAMP-dependent protein kinase catalytic subunit alpha OS=Cricetulus griseus OX=10029 GN=PRKACA PE=1 SV=2) HSP 1 Score: 574.318 bits (1479), Expect = 0.000e+0 Identity = 284/351 (80.91%), Postives = 316/351 (90.03%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK++FL+KWE PSQNTA LD FDR+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P17612|KAPCA_HUMAN (cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2) HSP 1 Score: 573.933 bits (1478), Expect = 0.000e+0 Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|Q9MZD9|KAPCA_SHEEP (cAMP-dependent protein kinase catalytic subunit alpha OS=Ovis aries OX=9940 GN=PRKACA PE=1 SV=3) HSP 1 Score: 571.622 bits (1472), Expect = 0.000e+0 Identity = 282/351 (80.34%), Postives = 316/351 (90.03%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG + VK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+H + ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+NFPFLV LEF F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++PF PK KG GD SNFDDYEEE +R++ EKC KEF+EF
Sbjct: 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A0X3NYD4 (cAMP-dependent protein kinase catalytic subunit alpha OS=Schistocephalus solidus OX=70667 GN=KAPCA PE=3 SV=1) HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0 Identity = 316/350 (90.29%), Postives = 336/350 (96.00%), Query Frame = 1
Query: 79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A+K+G+PADVKAFL+DAKKDFLEKWEKPSQNTACLDDFDR+KTLGTGSFGRVMLVQHK KDYYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV LE+HF+DNSNLYMVLEFVNGGEMFSHLR+IGRFSE HARFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF+ADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGV+DIKNHKWFA T+WF+IYK+EL++PF PKCKG GDASNFDDYEEEPLRIATTEKC K+FAEF
Sbjct: 1 MGNAAASKRGEPADVKAFLDDAKKDFLEKWEKPSQNTACLDDFDRLKTLGTGSFGRVMLVQHKAKKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVKLEYHFKDNSNLYMVLEFVNGGEMFSHLRKIGRFSEHHARFYASQVVLAFEYLHHLELVYRDLKPENILIDQQGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFYADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVSDIKNHKWFAPTDWFSIYKRELEAPFMPKCKGPGDASNFDDYEEEPLRIATTEKCVKDFAEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: C7DPD5 (Serine/threonine kinase; cAMP-dependent protein kinase catalytic subunit OS=Schistosoma mansoni OX=6183 PE=2 SV=1) HSP 1 Score: 635.18 bits (1637), Expect = 0.000e+0 Identity = 311/350 (88.86%), Postives = 336/350 (96.00%), Query Frame = 1
Query: 79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct: 1 MGNAQAAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JVC2 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma haematobium OX=6185 PE=2 SV=1) HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0 Identity = 309/350 (88.29%), Postives = 335/350 (95.71%), Query Frame = 1
Query: 79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMK LDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPEN+LIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct: 1 MGNAQAAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKTLDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENVLIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JWR5 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma japonicum OX=6182 GN=EWB00_007721 PE=2 SV=1) HSP 1 Score: 633.639 bits (1633), Expect = 0.000e+0 Identity = 310/350 (88.57%), Postives = 335/350 (95.71%), Query Frame = 1
Query: 79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKGDPADVKA LE+AKK+FLEKWEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSESH+RFYASQVVL FEYLHHLELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYE+IVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWFATT+WF+I+K+++++PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct: 1 MGNAQTAKKGDPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A5J4NMV3 (Protein kinase A OS=Paragonimus westermani OX=34504 GN=DEA37_0002990 PE=3 SV=1) HSP 1 Score: 627.091 bits (1616), Expect = 0.000e+0 Identity = 309/350 (88.29%), Postives = 332/350 (94.86%), Query Frame = 1
Query: 79 MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M TKKGDPADVKAFLE+AKK+FLE+WEKP+QNTA LD FDR+KTLGTGSFGRVMLVQHK +K+YYAMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV L++HF+DNSNLYMVLEFVNGGEMFS+LRR+GRF+E HARFYA QVVL FEYLH+LELVYRDLKPENILIDQ GYLK+TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIK HKWF+TT+W YK+ELD+PFTPKC GAGDASNFDDYEEEPLRIATTEKC+KEF+EF
Sbjct: 1 MGNAQTTKKGDPADVKAFLEEAKKEFLERWEKPTQNTATLDAFDRIKTLGTGSFGRVMLVQHKTSKNYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSYLRRVGRFNECHARFYAGQVVLAFEYLHYLELVYRDLKPENILIDQFGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFSTTDWIATYKRELDTPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 575.089 bits (1481), Expect = 0.000e+0 Identity = 283/351 (80.63%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG+ + VK FL AK+DFL KWE P Q+T CLDDF+R+KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++P PKC+G GD SNFDDYEEE +RI+ TEKC+KEF EF
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacab (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103023241]) HSP 1 Score: 569.696 bits (1467), Expect = 0.000e+0 Identity = 275/351 (78.35%), Postives = 316/351 (90.03%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M PA K+G+ + V+ FL A++DFL KWE P+QNTA LD FD +KTLGTGSFGRVMLV+H++N +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYASQ+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPI IYEKIVSGKVRFPSHF+SDLK+LLRNLLQVDLTKR+GNLKNGVNDIK HKWF+TT+W IY++ +++PF PKC+G GD SNFDDYEEE +R++ TEKC KEFAEF
Sbjct: 1 MGNTPAAKRGNEMESVREFLALAREDFLRKWETPAQNTASLDQFDLLKTLGTGSFGRVMLVRHRENGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEYSFKDNSNLYMVMEYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIHIYEKIVSGKVRFPSHFSSDLKELLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCGKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000056663.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0 Identity = 277/336 (82.44%), Postives = 310/336 (92.26%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+K FL AK+DFL KWE P Q+T CLDDF+R+KTLGTGSFGRVMLV+HK + YYAMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT+W IY++++++P PKC+G GD SNFDDYEEE +RI+ TEKC+KEF EF
Sbjct: 60 MKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112]) HSP 1 Score: 568.926 bits (1465), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M A KKG+ + VK FL AK+DFL KWE P Q+T LDDF+R+KTLGTGSFGRVMLV+HK + ++AMK+LDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIKNHKWFATT+W IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEF EF
Sbjct: 1 MGNAAAAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 277/338 (81.95%), Postives = 311/338 (92.01%), Query Frame = 1
Query: 115 ADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
DVK FL AK+DFL+KWE P+QNTA LD F+R+KTLGTGSFGRVMLV+HK+ ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFATT+W IY++++++PF PKCKG GD SNFDDYEEE +R++ TEKC KEFAEF
Sbjct: 82 VDVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 419
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 497.278 bits (1279), Expect = 1.501e-178 Identity = 227/265 (85.66%), Postives = 253/265 (95.47%), Query Frame = 1
Query: 334 EHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
EHTLNEKRILQAI+FPFLV LE+ F+DNSNLYMVLE+V GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF+TT+W IY++++++PF PKCKG GDASNFDDYEEE +RI++TEKC+KEFA+F
Sbjct: 24 EHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISSTEKCAKEFADF 288
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 254.988 bits (650), Expect = 1.010e-84 Identity = 132/168 (78.57%), Postives = 152/168 (90.48%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKV 624
VK FL AK+DFL+KWE P QNT+CLDDF+R+KTLGTGSFGRVMLV+HK Y+AMKILDKQKVVKLKQVEHTLNEKRILQAI+FPFLV LE+ ++DNSNLYMVLE+V GGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++V
Sbjct: 16 VKEFLAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 249.595 bits (636), Expect = 1.924e-80 Identity = 129/295 (43.73%), Postives = 188/295 (63.73%), Query Frame = 1
Query: 205 FDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEE 1077
D + TLG G FGRV LV+ K + +A+K L K+ VV+ +Q EH +EKRILQ + PF+V FRD +++++E GGE++S LR G F E ARF + VV YLH ++YRDLKPEN+L+D GY+K+ DFGFAK++ GR WT CGTPEY+ PE+I+++G+++ D WALGVL+YE+ AG PPF P++ Y I+ G +V FP+ +D++R L + + ++R GN K+GV D++ HKWF +W ++ +L SP + G D NFD + E+
Sbjct: 34 MDVIATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPED 328
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 243.817 bits (621), Expect = 4.108e-77 Identity = 129/315 (40.95%), Postives = 192/315 (60.95%), Query Frame = 1
Query: 175 PSQN-TACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRIL-QAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD-YEEEPLRIATTE 1101
PS N A DFD + LG GSFG+V+L +HK + +YA+K++ K +++ K+ +H + E+ +L + + PFLV L + F+ LY V+++VNGGE+F HL+R G F ES A+FYA+++ YLH L +VYRDLKPENIL+D G++ +TDFG K T T CGTPEYLAPE++ Y++ VDWW LG ++YEM G PPF++ Q+YE I+ ++ T+ +L LL D +R G + + +IKNH +F+T W ++ K + SP+ P G D NFD + EPL ++ +
Sbjct: 81 PSANLQAKPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSD-ILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMSMAQ 394
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 239.195 bits (609), Expect = 9.728e-75 Identity = 126/302 (41.72%), Postives = 185/302 (61.26%), Query Frame = 1
Query: 172 KPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLH-HLELVYRDLKPENILIDQTGYLKVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD 1065
KP ++ +++FD +K LG G+FG+V+LV+ K YYAMKIL K+ +V +V HTL E R+LQ PFL L++ F+ + L V+E+VNGGE+F HL R FSE RFY +++V +YLH +VYRDLK EN+++D+ G++K+ DFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM G PF+ +++E I+ +RFP ++D + LL LL+ D +R G + +I H +FA W ++Y +++ PF P+ D FD+
Sbjct: 140 KP-KSKVTMNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFDE 440
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 326.25 bits (835), Expect = 4.133e-110 Identity = 161/303 (53.14%), Postives = 221/303 (72.94%), Query Frame = 1
Query: 178 SQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPK-CKGAGDASNFDDYEEEPL 1083
S+ L DF ++TLGTGSFGRV LV+ N YYA+K+L KQ+VVK+KQVEHT +E+R+L+ + PFL+ + F+D N++MV++++ GGE+FS LR+ RF A+FYA++V+L EYLH ++YRDLKPENIL+D+ G++K+TDFGFAK V+ TWTLCGTP+Y+APE+I +K YNK+VDWW+LGVLIYEM AGY PF+ P++ YEKI+ GKV +P +F D+ DLL L+ DLT+R GNL++G DIK H WF+ W + K++++P+ P G GD S FD Y EE L
Sbjct: 61 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQL 363
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 313.153 bits (801), Expect = 9.311e-105 Identity = 151/322 (46.89%), Postives = 224/322 (69.57%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKC-KGAGDASNFDDYEEEPL 1083
V + E+ K F+ + + + L DF ++TLGTGSFGRV L++ + N YYAMK+L K+ VV+LKQVEHT +E+ +L + PF++ + F+D ++M+++++ GGE+FS LR+ RF A+FYA++V L EYLH +++YRDLKPENIL+D+ G++K+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK++DWW+ G+LIYEM AGY PF+ ++ YEKI++ ++RFP F D+KDLL L+ DL++R GNL+NG D+KNH WF W + + +++P+ P +G GD S FD Y EE +
Sbjct: 60 VTYYNEEQYKQFIAQ-ARVTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEEDI 380
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 306.605 bits (784), Expect = 4.290e-102 Identity = 146/296 (49.32%), Postives = 212/296 (71.62%), Query Frame = 1
Query: 193 CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKC-KGAGDASNFDDYEEE 1077
L DF ++TLGTGSFGRV L++ N +YA+K L K +VKLKQVEHT +E+R+L ++ PF++ + F+D+ ++MV++++ GGE+FS LR+ RF A+FYA++V L EYLH +++YRDLKPENIL+D+ G++K+TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+VDWW+ GVLIYEM AGY PF+ ++ YE I++ +++FP F D +DLL+ L+ DL++R GNL+NG D+KNH WF W + + +++P+ P +G GD S FD Y EE
Sbjct: 84 SLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 272.707 bits (696), Expect = 8.774e-86 Identity = 142/320 (44.38%), Postives = 201/320 (62.81%), Query Frame = 1
Query: 172 KPSQNTA-CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD--YEEEPLRIATTEKCSK 1113
KPS+N +DDFD +K +G GSFG+VM V+ K + YA+K + K +V +V HTL E+ +L ++ PF+V L+F F+ LY VL F+NGGE+F HL++ GRF S ARFY ++++ + LH L++VYRDLKPENIL+D G++ + DFG K + +T T CGTPEYLAPE++L GY KAVDWW LGVL+YEM G PP++ + ++Y+KI+ + FP F D KDLL LL D T+R G NG ++I+NH +F+ W + K P+ P + D SNFD+ E+P+ E S+
Sbjct: 335 KPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFDEEFTREKPIDSVVDEYLSE 652
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 263.462 bits (672), Expect = 2.843e-82 Identity = 138/319 (43.26%), Postives = 198/319 (62.07%), Query Frame = 1
Query: 172 KPSQNTA-CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDD--YEEEPLRIATTEKCS 1110
KPS+N +DDFD +K +G GSFG+VM V+ K + YA+K L K +V +V HTL E+ +L ++ PF+V L+F F+ LY+VL F+NGGE+F HL+ GRFS + +RFY ++++ + LH L+++YRDLKPENIL+D G++ + DFG K + +T T CGTPEYLAPEI+L +GY K VDWW LG+L+YEM G PP++ + +Y+KI+ + FP F KDLL LL D ++R G NG ++I+NH +F W + K P+ P K D +NFD +E+P+ E S
Sbjct: 332 KPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFDQEFTKEKPIDSVVDEYLS 648
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 333.954 bits (855), Expect = 2.518e-113 Identity = 166/302 (54.97%), Postives = 218/302 (72.19%), Query Frame = 1
Query: 190 ACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF-TSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIA 1092
L DF+ KTLGTG+FGRV+L + ++ ++YA+KI++ +V++LKQVEH NEK IL +I PF+V+L + D + LYM+LE+ GGE+F++LR GRF+ F+ S++V +YLH +VYRDLKPENIL+D+ G++K+TDFGFAK V +TWTLCGTPEYLAPEII SKG+NKAVDWWALG+LIYEM GYPPFF D P IYEKI+SGKV +P H + KDL++ LL D T+R G++KNG D+KNHKWF +W + +++L P PK GD NFDDY EE R A
Sbjct: 13 TTLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEEDWRGA 314
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7]) HSP 1 Score: 258.84 bits (660), Expect = 3.197e-80 Identity = 135/292 (46.23%), Postives = 187/292 (64.04%), Query Frame = 1
Query: 196 LDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNF 1059
L+D VKTLG G FGRV LVQ +K +A+K L K +V+ +Q +H ++EK+I+ N PF+V L F+D LYM+LE GGE+++ LR G F +S RFY V+ F+YLH +VYRDLKPEN+L+D GY K+ DFGFAK++ GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP T + L++ L + + +R G K G+ DI HKWF W + ++L+SP PK K DASNF
Sbjct: 349 LEDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSPVDASNF 640
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 246.514 bits (628), Expect = 4.623e-78 Identity = 130/354 (36.72%), Postives = 206/354 (58.19%), Query Frame = 1
Query: 76 LMTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRIL-QAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFD-DYEEEPLRIATTEKCSKEFA 1122
L P + + D + +DA + ++ E + A DF +K +G GSFG+V L ++K+ +YA+K+L+K + K + +H + E+ +L Q + PFLV L + F+ LY VL++VNGGE+F HL+R F ES ARFYA+++ YLH L+++YRDLKPENIL+D G++ +TDFG K G T T CGTPEYLAPE++ + Y+K+VDWW LG ++YEM G PPF++ ++Y+ I+ +R ++ + + +L LLQ D TKR G+ + DI+ H +F + W + + ++ P+ P G D +FD ++ EP+ + + F
Sbjct: 32 LSLDNPKNAQANDEDEQPGSDDADVEKIDLGES-NNPKAKPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFDPEFVREPVPGSVGKSADSNFV 384
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 237.269 bits (604), Expect = 2.087e-74 Identity = 121/308 (39.29%), Postives = 173/308 (56.17%), Query Frame = 1
Query: 160 EKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQ----HKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRV---KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFD 1062
E+ P + F+ +K LG G +G+V LV+ H K K + + + K HT E+ IL+ + PF+V L + F+ LY++LE+++GGE+F L R G F E A FY S++ + E+LH +VYRDLKPENIL+D G++K+TDFG K T T CGT EY+APEI+ G+ KAVDWW+LG L+Y+M G PPF AD + +KI+ GK+ P + T + KD +R LL+ R G + N IK H +F W ++ K+++ PF P G D S FD
Sbjct: 50 EETVNPKDEKVGPESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFD 357
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 231.876 bits (590), Expect = 4.690e-70 Identity = 131/297 (44.11%), Postives = 186/297 (62.63%), Query Frame = 1
Query: 151 DFLEKWEKPSQNTA--CLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRV-KGR-TWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFT 1023
D E+ K S+ A L+D + V TLGTG FGRV LV YA+K L K+ ++ +Q EH +EKRIL N PF+ + F+D +YM+LE GGE+++ LR G F ++ ARF + VV GFEYLH +VYRDLKPEN+L+D GY+K+ DFGFAK++ GR TWT CGTPEY+APEIIL+KG++ + D+W+LG+LI+E+ G PPF + P++ Y I+ G V FP + ++L++ L + + +R G K+G++DIK HK+ WF + P T
Sbjct: 311 DVPEEERKVSKEFADLTLEDLEVVATLGTGGFGRVELVT-------YALKCLKKKHILDTRQQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKHKYVVP--WFPLAGTHRRDPRT 598
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 570.852 bits (1470), Expect = 0.000e+0 Identity = 279/351 (79.49%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKG+ + VK FL AK+DFL KWE P Q+T CL+DFDR+KTLGTGSFGRVMLV+HK ++ Y+AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFATT+W IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct: 1 MGNAATAKKGNELESVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 569.311 bits (1466), Expect = 0.000e+0 Identity = 279/354 (78.81%), Postives = 317/354 (89.55%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD----VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M KKG+ + VK FL AK+DFL KWE P Q+T CL+DFDR+KTLGTGSFGRVMLV+HK ++ Y+AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE+ F+DNSNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LID GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFATT+W IY++++++PF PKC+G GD SNFDDYEEE +R++ TEKC+KEFAEF
Sbjct: 1 MGNAATAKKGNELESDTFVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 354
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 278/351 (79.20%), Postives = 316/351 (90.03%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M P KKG+ + VK FL AK+DFL+KWE P+Q TA LD F+R+KTLGTGSFGRVMLV+HK+ ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE F+D SNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIK HKWFATT+W IY++++++PF PKCKG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct: 1 MGNTPTAKKGNEVESVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0 Identity = 274/337 (81.31%), Postives = 310/337 (91.99%), Query Frame = 1
Query: 118 DVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
DVK FL AK+DFL+KWE P+Q TA LD F+R+KTLGTGSFGRVMLV+HK+ ++AMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV LE F+D SNLYMV+E+V GGEMFSHLRRIGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKRFGNL+NGVNDIK HKWFATT+W IY++++++PF PKCKG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct: 41 DVKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 377
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000040218.1 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 563.533 bits (1451), Expect = 0.000e+0 Identity = 274/351 (78.06%), Postives = 317/351 (90.31%), Query Frame = 1
Query: 79 MTTEPATKKGDPAD-VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M P +KG+ + VK FL AK+DFL+KWE PSQNTA L+ F+R+KTLGTGSFGRVMLV+H++ +YAMKIL+KQKVVKLKQ+EHTLNEKRILQA++FPFLV LEF F+DN+NLYMV+E+V GGEMFSHLR+IGRFSE HARFYA+Q+VL FEYLH L+L+YRDLKPEN+LIDQ GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF+SDLKDLLRNLLQVDLTKR+GNLKNGVNDIK HKWFA T+W I++K++++PF PK KG GD SNFDDYEEE +R++ +EKC+KEFAEF
Sbjct: 1 MGNAPTARKGNEMESVKEFLAKAKEDFLKKWENPSQNTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFAATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0 Identity = 280/336 (83.33%), Postives = 309/336 (91.96%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
VKAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF +W I+KKEL++PF P KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct: 172 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 507
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 566.614 bits (1459), Expect = 0.000e+0 Identity = 280/336 (83.33%), Postives = 309/336 (91.96%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
VKAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF +W I+KKEL++PF P KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct: 295 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 630
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 566.229 bits (1458), Expect = 0.000e+0 Identity = 279/336 (83.04%), Postives = 309/336 (91.96%), Query Frame = 1
Query: 121 VKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+KAFLE+AK+ F+EKW+KPSQNTA L DF+R++TLGTGSFGRVMLVQHK K+Y A+KILDKQKVVKLKQVEHTLNEKRILQAI F FLV L++HF+DNSNLYMVLEFVNGGEMFSHLRRIGRFSE H+RFYA+Q+VL FEYLH+L+L+YRDLKPEN+LID GY+KVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF++DLKDLLRNLLQVDLTKR+GNLKN V DIK HKWF +W I+KKEL++PF P KG GD+SNFDDYEEEPLRIA TEKC KEFA+F
Sbjct: 247 MKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 582
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000016651.1 (SMESG000016651.1) HSP 1 Score: 526.168 bits (1354), Expect = 0.000e+0 Identity = 254/352 (72.16%), Postives = 308/352 (87.50%), Query Frame = 1
Query: 79 MTTEPATKKG--DPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
M P K+ D + VK FLE+AKK+F +K++ P Q T LD+F+ +KTLGTGSFGRV+L HKK+K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI+FPFL+ L++ F+DNSNLYMVLEFVNGGEMFSHLRR+G+FSE+HA+FYASQVVL FEYLHHL+L+YRDLKPENILID GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF+ +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + +W++ +KKEL +PF PKC+G GD SNFD+YEEE L+I+TT KC+ EF EF
Sbjct: 1 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAVKVLDKLKIVKLKQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1) HSP 1 Score: 483.797 bits (1244), Expect = 1.098e-171 Identity = 236/346 (68.21%), Postives = 289/346 (83.53%), Query Frame = 1
Query: 94 ATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGTGSFGRVMLVQHKKNKDYYAMXXXXXXXXXXXXXXEHTLNEKRILQAINFPFLVHLEFHFRDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHARFYASQVVLGFEYLHHLELVYRDLKPENILIDQTGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFTSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF-ATTEWFNIYKKELDSPFTPKCKGAGDASNFDDYEEEPLRIATTEKCSKEFAEF 1128
+KK + +V+ FLE+A+++F +KW+ P N A L +F RVKTLGTG+FG V+LV + YYAMK+L+KQK+VK+KQVEHTLNEKRILQA+NFPFLV+L + F+DNS LY+VLE+V GGEMFSHLR+ GR+SE A FYASQVV+ FEYLH+L++VYRDLKPENILI++ GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALG+LIYEM GYPPF ADQPI IYEKIV GK +FP++ + D KDL+R LLQ DLTKR+GNLKNGV DIKNHKWF ++W NIYK+++ PF P+ K GD S FDDY+EEPL+I+ EKC+KEF +F
Sbjct: 5 TSKKENNCEVEEFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 350 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025257 ID=SMED30025257|Name=cAMP-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1189bpback to top protein sequence of SMED30025257-orf-1 >SMED30025257-orf-1 ID=SMED30025257-orf-1|Name=SMED30025257-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=351bp MTTEPATKKGDPADVKAFLEDAKKDFLEKWEKPSQNTACLDDFDRVKTLGback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
