Fzd-1/2/7
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025215 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 12
Homology
BLAST of Fzd-1/2/7 vs. Ensembl Human
Match: FZD1 (frizzled class receptor 1 [Source:HGNC Symbol;Acc:HGNC:4038]) HSP 1 Score: 502.286 bits (1292), Expect = 1.328e-168 Identity = 263/556 (47.30%), Postives = 355/556 (63.85%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL--------------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP ++ C+ +P LC+ N ++K P SL SCP++L++P ++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY V + Y+AGF L D+V C F + + V QGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W + C+S Y C + GG P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 103 NGERGISVP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDK-GTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHF-LGE----KDCGAPCEPTKVYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGA-----RTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSW-VAQSCKS--YAIPCPHLQAG-----GGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 637
BLAST of Fzd-1/2/7 vs. Ensembl Human
Match: FZD7 (frizzled class receptor 7 [Source:HGNC Symbol;Acc:HGNC:4045]) HSP 1 Score: 488.804 bits (1257), Expect = 1.899e-164 Identity = 252/542 (46.49%), Postives = 345/542 (63.65%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEK--------------------------------ESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++ +A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P +C+ N ++ P SCP+ L++P ++ L + +DCG PC YF E R+FAR+WV +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY +V + +VAGF L D+ C F++ + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD L+GVC+ GLS LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +V+ACYF+E W + W L+ C+S Y C H P++ P+F +FMIKYLM++IVGIT+G WIWSGKTL SW+ F+ RL Sbjct: 49 CQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGPGGGPTAYPTAPYLPDLPFTALPPGASDGRGRPAFPFSCPRQLKVPPYLGYRF-LGE----RDCGAPCEPGRANGLMYFKEEE-RRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGY-----RTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTW-LLQTCKS--YAVPCPPGH-FPPMS-----------PDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRL 564
BLAST of Fzd-1/2/7 vs. Ensembl Human
Match: FZD2 (frizzled class receptor 2 [Source:HGNC Symbol;Acc:HGNC:4040]) HSP 1 Score: 475.322 bits (1222), Expect = 2.776e-159 Identity = 246/543 (45.30%), Postives = 343/543 (63.17%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN---NLCIRDNQTEK------ESAPNVSLS---------------------------CPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRS+C + ++ CE ++ KF F+WP+ + C+ +P + +C+ N +E +AP L CP+ L++P +K L + +DC PC +F++ R FAR+W+ WS +C ST FTV T+L+DM+RF+YPERPIIFLS CY +V + Y+AGF L ++V C F+ + VVQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ ++DGD L+GVCF GL+ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLE+L+ RIG+FSVLY VPA +VIACYF+E W + W CK + P + P+F ++MIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 39 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKF-LGE----RDCAAPCEPARPDGSMFFSQEETR-FARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGY-----RTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSW----------VSQHCKSLAIPCPAH-----YTPRMSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 555
BLAST of Fzd-1/2/7 vs. Ensembl Human
Match: FZD5 (frizzled class receptor 5 [Source:HGNC Symbol;Acc:HGNC:4043]) HSP 1 Score: 421.779 bits (1083), Expect = 2.981e-138 Identity = 233/550 (42.36%), Postives = 323/550 (58.73%), Query Frame = 3 Query: 108 NQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP-----ENNLCIRDNQTEKESAPNVSLSCPKSL-----------QIPVSYDF--------------------KIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPG 1643 P C++I VP C+G+ Y +T PN H TQDEA LE++++ PL+ I+C L+ FLCS+Y P+C K LPPCRS+C + K C P+++++ F WP+ MSCD P LC+ N++E +AP +L + P F K+R Q + +C +PC + F+ + R FA W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACYL V L ++ + + VAC+ + P + C I+F+L+YFF MAS+IWWV+L++TW+LAA W +E+I +QYFH AAW IP+ K+I LALS VDGDP+ G+C+ G + ++LRGF++ PL +YLL+GT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIF++LY VPA +V+ACY +E + + W C PG + KPE+ + M+KY M L+VGITSG+WIWSGKT+ SW+ F SR C R G Sbjct: 29 KAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLPGPPGAPASGGECPAGGPFVCKCREPFVPILKESHPLYNKVRTGQ---VPNCAVPCYQPSFSA-DERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHNHIHYETTGPAL---------CTIVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQ----HYRESWEAALTCAC-----------------PGHDTGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTVESWRRFTSRCCCRPRRG 544
BLAST of Fzd-1/2/7 vs. Ensembl Human
Match: FZD10 (frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039]) HSP 1 Score: 396.356 bits (1017), Expect = 1.709e-128 Identity = 224/526 (42.59%), Postives = 314/526 (59.70%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCT-IMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCP---KSLQIPVSYDFKIRLSQNSVIQDCG-------------------------IPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLN-DKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWK 1604 C+ I++P C+ + Y MT PN M H Q EAA++++E+ PL+ CHG L+ FLCSLY P+CT + +P CR +C Q + +C PI+++F FKWP S+ C P N D APN P L P+ + +Q ++D G P Y++ + ++FA VW+A+W+ +C S+ FTVLTFLID RF+YPERPIIFLS CY V + Y+ F + +AC D ++ +G + C ++F++LY+F MAS++WWVVLT+TW+LAA W HE+I NS YFH AAWAIPA KTI IL + +V GD LTGVC+ G D + L GF++ PL YL+IGT F+++GFV++F IR ++KTGG TDKLEKL+ RIG+FSVLY VPA VIACYF+E +N M W ++ +A++K CK + K + + L+ + P E+FM+K M L+VGITSG+WIW+ KTL SW+ Sbjct: 33 KCQPIEIPMCKDIGYNMTRMPNLMGHENQREAAIQLHEFAPLVEYGCHGHLRFFLCSLYAPMCTEQVSTPIPACRVMCEQARLKCSPIMEQFNFKWPDSLDCRKLPNKN----DPNYLCMEAPNNGSDEPTRGSGLFPPLFRPQRPHSAQEHPLKDGGPGRGGCDNPGKFHHVEKSASCAPLCTPGVDVYWSRED-KRFAVVWLAIWAVLCFFSSAFTVLTFLIDPARFRYPERPIIFLSMCYCVYSVGYLIRLFAGAESIAC-------DRDSGQLYVIQEGLESTGCTLVFLVLYYFGMASSLWWVVLTLTWFLAAGKKWGHEAIEANSSYFHLAAWAIPAVKTILILVMRRVAGDELTGVCYVGSMDVNALTGFVLIPLACYLVIGTSFILSGFVALFHIRRVMKTGGENTDKLEKLMVRIGLFSVLYTVPATCVIACYFYERLN----MDYWKIL----AAQHK--CKMNNQTKTL----DCLMAASIPAVEIFMVKIFMLLVVGITSGMWIWTSKTLQSWQ 532
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9969413:1 gene:WBGene00003397.1 transcript:T23D8.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5) HSP 1 Score: 328.176 bits (840), Expect = 6.773e-103 Identity = 189/556 (33.99%), Postives = 289/556 (51.98%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKES---------------APNVSLS---CPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRY----YFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTP-KIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTD----KLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHK-----------PINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGR 1631 +I ++N CE I +P C+ L Y T+FPN + H+TQ EA I ++ PL+++KC ++LFLC++Y PVCT+++K + PCR LCL K CE ++KKF F+WP + C+ +P +LC+ N +E + A V LS CP + F + L + +C + C + +R+ R+W A WS C +LFT++TFL+D+ RF YP RPI++L+ CYL + Y+ G D AC + G TP +V QG + C L ++ YFF M+S WW+VL + W+LAA W ESI S YFH W +PA ++ +L + VDGD TG+C G +PS L F P+ + L +G L+ G SM IR+ IK + + KLEKL+ RIG F+++Y +P + A +++++N+ W++ W C ++ D + P++P A PE +F++KY+ L+VGIT IW+ S KTL S+ + L R Sbjct: 23 TSISSMNGFSTTRKCEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYAPVCTVLEKPIQPCRELCLSAKNGCESLMKKFGFQWPDQLDCNKFPVTDLCVGKNSSESSNSKKSSNDVTFGVSTIANEVVLSPKKCPHHMHTTSGSHFSLPLLSGR-LPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPVRPILYLAFCYLAISTVYMIGVVGEDGFACG-------TYGSTPTTLVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVVSLALGAVLLVCGIWSMIRIRSYIKLQHADVERNISKLEKLMLRIGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGW----------LHHRCVRLQDRELFGFTYPVDDCPMDPKVAA------PEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSYHKAYLALSSR 554
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Match: mom-5 (pep chromosome:WBcel235:I:9965580:9970037:1 gene:WBGene00003397.1 transcript:T23D8.1b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mom-5) HSP 1 Score: 327.791 bits (839), Expect = 1.059e-102 Identity = 189/558 (33.87%), Postives = 289/558 (51.79%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCI---------------RDNQTEKES--APNVSLS---CPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRY----YFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTP-KIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTD----KLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHK-----------PINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGR 1631 +I ++N CE I +P C+ L Y T+FPN + H+TQ EA I ++ PL+++KC ++LFLC++Y PVCT+++K + PCR LCL K CE ++KKF F+WP + C+ +P +LC+ ++ T S A V LS CP + F + L + +C + C + +R+ R+W A WS C +LFT++TFL+D+ RF YP RPI++L+ CYL + Y+ G D AC + G TP +V QG + C L ++ YFF M+S WW+VL + W+LAA W ESI S YFH W +PA ++ +L + VDGD TG+C G +PS L F P+ + L +G L+ G SM IR+ IK + + KLEKL+ RIG F+++Y +P + A +++++N+ W++ W C ++ D + P++P A PE +F++KY+ L+VGIT IW+ S KTL S+ + L R Sbjct: 23 TSISSMNGFSTTRKCEHITIPMCKNLDYNQTVFPNLLGHTTQSEAGPAIAQFNPLIKVKCSEDIRLFLCTVYAPVCTVLEKPIQPCRELCLSAKNGCESLMKKFGFQWPDQLDCNKFPVTDLCVGKNSSESSNSKNYRSSNDVTFGVSTIANEVVLSPKKCPHHMHTTSGSHFSLPLLSGR-LPECSLTCEADNQVPMMFDGRVRRILRIWTAAWSVACFVCSLFTLVTFLVDLSRFAYPVRPILYLAFCYLAISTVYMIGVVGEDGFACG-------TYGSTPTTLVTQGGENVGCSALAVVHYFFFMSSCAWWLVLCLAWFLAANLKWGAESIAALSPYFHAMCWGVPAVLSVTVLVTNSVDGDVFTGICSVGNLNPSALVYFFFTPIVVSLALGAVLLVCGIWSMIRIRSYIKLQHADVERNISKLEKLMLRIGAFAIMYSLPTAMNAAIMWYQAVNMPAWLEGW----------LHHRCVRLQDRELFGFTYPVDDCPMDPKVAA------PEIIVFLLKYVSQLVVGITCAIWVVSSKTLSSYHKAYLALSSR 556
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Match: cfz-2 (Frizzled-2 [Source:UniProtKB/Swiss-Prot;Acc:G5ECQ2]) HSP 1 Score: 282.722 bits (722), Expect = 1.384e-85 Identity = 186/618 (30.10%), Postives = 306/618 (49.51%), Query Frame = 3 Query: 45 FLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE-------NNLCIRDNQTE----------------------KESAPNVSLS--------CPKSLQIPVSYDFKIRLSQNSVI---QDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFES---CIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGG---SKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFF-----SRLCGRLNPGDP-WTRSDWLEK---NNGYYQRHFVGPTANKM 1727 L +S +FL + + A+ + CE+I +P C+G+ Y MT FPN H Q+EA LE++++ PL+ + C L+ FLC++Y P+C K + PC LC++ + +C PI+ K+ F+WP+++SC+ P+ N+C T P V +S P Q + F+ S+ S + +C C+ E + W+A WS C FT LTFLI+ RFQYPERPI L+ C L+V + ++ +F+ ++++AC DS + ++G S C ++F+L YFF MA+++WWV+L++TW L+A W+ E+I S +FH W +PA +T+ ++ + +DGDP+TG+C+ G +D R F++ PL +Y ++G FL+ GF +++ IR ++ K+ +L+++IGIFS+LY +P++++I F+E + W Q +C + + G ++LI S +IK I+G TSG W+ S KTL SWK SR + P D + +SD N H G +K+ Sbjct: 2 LLRISVLFLLLGSCGALFG--KRQKCEQITIPLCKGIGYNMTSFPNSYGHEKQEEAGLEVHQFYPLVEVGCFQHLKFFLCTMYTPICQENYDKPILPCMELCVEARSKCSPIMAKYGFRWPETLSCEALPKMSDQMSTGNICAAPPDTPKKQHKGHHHKNQNQNQNQNHNYSPDGPEVGISKIDNEVIAGPSECQCTCNQPFQFVASEKSKVGNVTNCAYSCHSPALAESH--SLVSNWMAFWSITCCVLASFTFLTFLIETDRFQYPERPIFMLAFCQLMVAVGFMIRYFVGHEEIAC-------DS------MRIKGADDNSGSLCFVVFLLTYFFGMAASVWWVILSLTWVLSAASKWSPEAISSFSFHFHVVGWCLPAIQTVLVIVFNAIDGDPITGICYVGNTDLQFQRIFVLFPLLVYFIVGVLFLVIGFCNLWSIRNEVQKQHPSLESAHKITQLMSKIGIFSLLYTIPSLLIICVLFYEQNHRSLWEQS----QLCSCSPKQ------------TIGDSSLIIS--------LIKTCCMCILGWTSGFWVCSTKTLSSWKNAICCLGSSRSLPKYQPADILYAKSDMSSSQFYNTSLRHNHLYGGIPDKL 578
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Match: lin-17 (Transmembrane receptor LIN-17 [Source:UniProtKB/TrEMBL;Acc:G5EDV1]) HSP 1 Score: 256.144 bits (653), Expect = 8.403e-76 Identity = 167/544 (30.70%), Postives = 263/544 (48.35%), Query Frame = 3 Query: 90 AVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN-NLCIRDNQTEKE---SAPNVSL-----------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFES-CIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYF-FSRLCGRL---NPGDPWTR 1658 ++ D + C I + C+ L Y T FPN +LH+ Q + PLM+ KCH + F+CS++ P+C I M +A+ C+S+C Q+K +C IL++F WP+ ++C +P+ LC++ + E SAP + CP L +D K C C + ++ R W ++ G LF+ LTF ID KRF++PER + +LS C + L Y+ F++ P + + G + GT S C+ F+L YFFS A+A+WW++ + T YL+ W E I S Y HF AW + + TI +L +KVD LT +C G + L F+I P I ++IGT F++ GF SM R +T G+ T KLEKL+ ++G F L+++P V+ + C ++ M L +W + + + K + H P P+ E++M + SL G + +W+ S KT+ +WK F F +C NP +P TR Sbjct: 18 SIFDQAVKGKCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMKPTEDEITGGFSAPRLPTKGSSSSSSKPTGCPSDLVDVDPHDPK---------SHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFID------APIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTR--------MTIDCKQQSGACHRPTP-------------PQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTR 525
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Match: lin-17 (Transmembrane receptor LIN-17 [Source:UniProtKB/TrEMBL;Acc:G5EDV1]) HSP 1 Score: 256.144 bits (653), Expect = 8.403e-76 Identity = 167/544 (30.70%), Postives = 263/544 (48.35%), Query Frame = 3 Query: 90 AVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN-NLCIRDNQTEKE---SAPNVSL-----------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFES-CIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYF-FSRLCGRL---NPGDPWTR 1658 ++ D + C I + C+ L Y T FPN +LH+ Q + PLM+ KCH + F+CS++ P+C I M +A+ C+S+C Q+K +C IL++F WP+ ++C +P+ LC++ + E SAP + CP L +D K C C + ++ R W ++ G LF+ LTF ID KRF++PER + +LS C + L Y+ F++ P + + G + GT S C+ F+L YFFS A+A+WW++ + T YL+ W E I S Y HF AW + + TI +L +KVD LT +C G + L F+I P I ++IGT F++ GF SM R +T G+ T KLEKL+ ++G F L+++P V+ + C ++ M L +W + + + K + H P P+ E++M + SL G + +W+ S KT+ +WK F F +C NP +P TR Sbjct: 18 SIFDQAVKGKCIPIDIELCKDLPYNYTYFPNTILHNDQHTLQTHTEHFKPLMKTKCHPHIHFFICSVFAPMCPIGMPQAVTSCKSVCEQVKADCFSILEEFGIGWPEPLNCAQFPDPPELCMKPTEDEITGGFSAPRLPTKGSSSSSSKPTGCPSDLVDVDPHDPK---------SHCAFACQSNVMFSTDNKRMVRSWSIWFAAANAGVALFSFLTFAIDRKRFRFPERCVFYLSLCIFISSLPYLTPLFID------APIRSCHALGNGRSYLSIGTFDNSYCLASFLLNYFFSTAAALWWLMFSFTLYLSGGRKWVPEGIEACSSYVHFVAWGLSSLATIIVLIFNKVDASELTALCSVGNLNSIALLWFVIVPRTICIVIGTCFIVGGFASMCRERISFRTRGTDTSKLEKLMVKMGFFCALFILPNVIELVCQCYKFMILTQWTR--------MTIDCKQQSGACHRPTP-------------PQAEIYMTAVISSLATGFSCLMWVLSAKTVHAWKNFIFCGMCSSAPVKNPIEPSTR 525
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Match: fz (gene:FBgn0001085 transcript:FBtr0075743) HSP 1 Score: 441.425 bits (1134), Expect = 3.388e-146 Identity = 236/546 (43.22%), Postives = 333/546 (60.99%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN---NLCIRDN-----------------------QTEKESAP-NVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKI--VVQGTK-FESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSD 1664 CE I + C+ + Y MTI PN + H+ Q+EA LE++++ PL++I C LQLFLCSLY PVCTI+++ +PPCRSLC + + CE ++K + F WP+++ C +P + +LC+ +N QT ES N+ CP L+ P+ +++++ + DCG PC+ +F E R R WV W+ +CV S LFTVLTFLID RF+YPER I+FL+ CYLVVG YVAG D V+C PF G+ + + QG + SC +LFM LYF MA+ WW L W+LAA W HE+I S FH AWA+PA +TI +LAL+KV+GD L+GVCF G D +L FLI PLCIYL IG FL+AGF+S+F IRT++KT G +TDKLE+L+ RIG FS L+++PAV ++ C F+E N +WM +W+ DIC+ + C P +P +P F++FM+KYL S++VG+TS +W++S KT++SW+ F RL G+ +P TR+ Sbjct: 52 RCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLC-ESARVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKD-LHDCGAPCHAMFFPERE-RTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHR-DICKP--FSIPCPA--ARAPGSP-------EARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGK----EPRTRAQ 578
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Match: fz (gene:FBgn0001085 transcript:FBtr0330102) HSP 1 Score: 441.81 bits (1135), Expect = 6.470e-146 Identity = 236/546 (43.22%), Postives = 333/546 (60.99%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN---NLCIRDN-----------------------QTEKESAP-NVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKI--VVQGTK-FESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSD 1664 CE I + C+ + Y MTI PN + H+ Q+EA LE++++ PL++I C LQLFLCSLY PVCTI+++ +PPCRSLC + + CE ++K + F WP+++ C +P + +LC+ +N QT ES N+ CP L+ P+ +++++ + DCG PC+ +F E R R WV W+ +CV S LFTVLTFLID RF+YPER I+FL+ CYLVVG YVAG D V+C PF G+ + + QG + SC +LFM LYF MA+ WW L W+LAA W HE+I S FH AWA+PA +TI +LAL+KV+GD L+GVCF G D +L FLI PLCIYL IG FL+AGF+S+F IRT++KT G +TDKLE+L+ RIG FS L+++PAV ++ C F+E N +WM +W+ DIC+ + C P +P +P F++FM+KYL S++VG+TS +W++S KT++SW+ F RL G+ +P TR+ Sbjct: 52 RCEPITISICKNIPYNMTIMPNLIGHTKQEEAGLEVHQFAPLVKIGCSDDLQLFLCSLYVPVCTILERPIPPCRSLC-ESARVCEKLMKTYNFNWPENLECSKFPVHGGEDLCVAENTTSSASTAATPTRSVAKVTTRKHQTGVESPHRNIGFVCPVQLKTPLGMGYELKVGGKD-LHDCGAPCHAMFFPERE-RTVLRYWVGSWAAVCVASCLFTVLTFLIDSSRFRYPERAIVFLAVCYLVVGCAYVAGLGAGDSVSCREPFPPPVKLGRLQMMSTITQGHRQTTSCTVLFMALYFCCMAAFAWWSCLAFAWFLAAGLKWGHEAIENKSHLFHLVAWAVPALQTISVLALAKVEGDILSGVCFVGQLDTHSLGAFLILPLCIYLSIGALFLLAGFISLFRIRTVMKTDGKRTDKLERLMLRIGFFSGLFILPAVGLLGCLFYEYYNFDEWMIQWHR-DICKP--FSIPCPA--ARAPGSP-------EARPIFQIFMVKYLCSMLVGVTSSVWLYSSKTMVSWRNFVERLQGK----EPRTRAQ 578
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0112890) HSP 1 Score: 323.168 bits (827), Expect = 1.898e-99 Identity = 183/423 (43.26%), Postives = 258/423 (60.99%), Query Frame = 3 Query: 432 ENNLCIRDNQTEKESAPNVSLSCPKSL-------------QIPVSYD-----FKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKT-----GGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCG 1628 N+ ++ Q EK S S SC L Q+P+ + + + + + + +CGIPC +F+ + + FA +W+ALWS +C STL T+ TF+ID +RF+YPERPI+FLSACY +V + Y++ FL N+++AC G + STG SC ++F+L YFF MAS+IWWV+L+ TW+LAA W +E+I ++SQYFH AAW IP +++ +L LS VDGDP+ G+C+ G +P L+ F++APL +YL+IGT FL+AGFVS+F IR++IK G K DKLEKL+ RIGIFSVLY VPA +VI CY +E+ W++ C A+ K PG +KP + + M+KY M+L VGITSG+WIWSGKTL SW+ F+ RL G Sbjct: 235 RNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSN-DEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGP-----------HSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKAL----ACPCAQVK------------GPG-------KKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLG 622 HSP 2 Score: 119.783 bits (299), Expect = 1.291e-27 Identity = 53/118 (44.92%), Postives = 78/118 (66.10%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRD 455 CE+I +P C+G+ Y MT FPN M H TQDEA LE++++ PL+ IKC L+ FLCS+Y P+C K LP CRS+C + + C PI++++ F+WP+ M+C+ P +NLC+ Sbjct: 63 RCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQ 180
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0075029) HSP 1 Score: 323.168 bits (827), Expect = 1.898e-99 Identity = 183/423 (43.26%), Postives = 258/423 (60.99%), Query Frame = 3 Query: 432 ENNLCIRDNQTEKESAPNVSLSCPKSL-------------QIPVSYD-----FKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKT-----GGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCG 1628 N+ ++ Q EK S S SC L Q+P+ + + + + + + +CGIPC +F+ + + FA +W+ALWS +C STL T+ TF+ID +RF+YPERPI+FLSACY +V + Y++ FL N+++AC G + STG SC ++F+L YFF MAS+IWWV+L+ TW+LAA W +E+I ++SQYFH AAW IP +++ +L LS VDGDP+ G+C+ G +P L+ F++APL +YL+IGT FL+AGFVS+F IR++IK G K DKLEKL+ RIGIFSVLY VPA +VI CY +E+ W++ C A+ K PG +KP + + M+KY M+L VGITSG+WIWSGKTL SW+ F+ RL G Sbjct: 235 RNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSN-DEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGP-----------HSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKAL----ACPCAQVK------------GPG-------KKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLG 622 HSP 2 Score: 119.783 bits (299), Expect = 1.291e-27 Identity = 53/118 (44.92%), Postives = 78/118 (66.10%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRD 455 CE+I +P C+G+ Y MT FPN M H TQDEA LE++++ PL+ IKC L+ FLCS+Y P+C K LP CRS+C + + C PI++++ F+WP+ M+C+ P +NLC+ Sbjct: 63 RCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQ 180
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Match: fz2 (gene:FBgn0016797 transcript:FBtr0332735) HSP 1 Score: 323.168 bits (827), Expect = 1.898e-99 Identity = 183/423 (43.26%), Postives = 258/423 (60.99%), Query Frame = 3 Query: 432 ENNLCIRDNQTEKESAPNVSLSCPKSL-------------QIPVSYD-----FKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKT-----GGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCG 1628 N+ ++ Q EK S S SC L Q+P+ + + + + + + +CGIPC +F+ + + FA +W+ALWS +C STL T+ TF+ID +RF+YPERPI+FLSACY +V + Y++ FL N+++AC G + STG SC ++F+L YFF MAS+IWWV+L+ TW+LAA W +E+I ++SQYFH AAW IP +++ +L LS VDGDP+ G+C+ G +P L+ F++APL +YL+IGT FL+AGFVS+F IR++IK G K DKLEKL+ RIGIFSVLY VPA +VI CY +E+ W++ C A+ K PG +KP + + M+KY M+L VGITSG+WIWSGKTL SW+ F+ RL G Sbjct: 235 RNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSN-DEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGP-----------HSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKAL----ACPCAQVK------------GPG-------KKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLG 622 HSP 2 Score: 119.783 bits (299), Expect = 1.291e-27 Identity = 53/118 (44.92%), Postives = 78/118 (66.10%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRD 455 CE+I +P C+G+ Y MT FPN M H TQDEA LE++++ PL+ IKC L+ FLCS+Y P+C K LP CRS+C + + C PI++++ F+WP+ M+C+ P +NLC+ Sbjct: 63 RCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQ 180
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Match: fzd1 (frizzled class receptor 1 [Source:ZFIN;Acc:ZDB-GENE-990415-219]) HSP 1 Score: 505.368 bits (1300), Expect = 1.541e-171 Identity = 262/524 (50.00%), Postives = 347/524 (66.22%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENN--LCIRDN---------------QTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP+S++C+ +P + LC+ N Q E + CP SL++P +++ N CG PC YF+E + +KFAR+W+ +WS +C STLFTVLT+L+DMKRF YPERPIIFLS CY +V + Y+AGF L DKV C F N+ T VVQGTK E C ILFM+LYFFSM+S+IWWV+L +TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD L+GVCF G++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIGIFSVLY VPA +VIACYF+E W Q W C++ Y C H P P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 33 CQPISIPLCTDIAYNETIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPESLACESFPVHGGELCVGQNTTGPSPPVSPTPDATQAPPEPSQRGRFQCPPSLRVPPYLNYRFMGEDN-----CGAPCEPRKLHGMMYFSE-DEQKFARIWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTMVSIAYIAGFLLEDKVVCNEQFENEFRT------VVQGTKKEGCTILFMMLYFFSMSSSIWWVILALTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAVGQVDGDVLSGVCFVGINSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFRAHWEQTWS-AHSCKT--YAVPCPA---HNP----------QMNPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 528
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223]) HSP 1 Score: 498.434 bits (1282), Expect = 1.385e-168 Identity = 256/560 (45.71%), Postives = 353/560 (63.04%), Query Frame = 3 Query: 60 FVFLFINNIRAVNDPYNQPN---------CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESA---------------------PNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 F+ LF ++ + Y+ C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P +C+ N ++ S PN +CP L++P + + DCG PC YF E + KF R+WV +WS +C STLFTVLT+L+DM+RF+YPERPIIFLS CY +V + Y AGFFL DKV C F++ K V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD LTGVC+ G+ + +LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W++ CK+ P+N P+F +FMIKYLM++IVGITSG WIWSGKTL SW+ F+ RL Sbjct: 16 FLLLFTVALQTTSGQYHGEKGISIPEHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSMDLKFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDAGSPTSNPTPYVPELITLQPNLVVRPNQQFTCPLQLKVPTYLKYHFMGEK-----DCGAPCEPTRPNGLMYFREEEV-KFGRLWVGIWSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYAAGFFLEDKVVCIDKFSDDGY-----KTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDMLTGVCYVGIYNVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHM----------QTCKRFAVPCPVNNFA-----PMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL 549
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223]) HSP 1 Score: 498.434 bits (1282), Expect = 1.385e-168 Identity = 256/560 (45.71%), Postives = 353/560 (63.04%), Query Frame = 3 Query: 60 FVFLFINNIRAVNDPYNQPN---------CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESA---------------------PNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 F+ LF ++ + Y+ C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P +C+ N ++ S PN +CP L++P + + DCG PC YF E + KF R+WV +WS +C STLFTVLT+L+DM+RF+YPERPIIFLS CY +V + Y AGFFL DKV C F++ K V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD LTGVC+ G+ + +LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W++ CK+ P+N P+F +FMIKYLM++IVGITSG WIWSGKTL SW+ F+ RL Sbjct: 16 FLLLFTVALQTTSGQYHGEKGISIPEHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSMDLKFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDAGSPTSNPTPYVPELITLQPNLVVRPNQQFTCPLQLKVPTYLKYHFMGEK-----DCGAPCEPTRPNGLMYFREEEV-KFGRLWVGIWSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYAAGFFLEDKVVCIDKFSDDGY-----KTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDMLTGVCYVGIYNVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHM----------QTCKRFAVPCPVNNFA-----PMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL 549
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224]) HSP 1 Score: 498.049 bits (1281), Expect = 1.532e-168 Identity = 251/527 (47.63%), Postives = 350/527 (66.41%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQT-----------------EKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNR------YYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H QD+A LE++++ PL++++C L+ FLCS+Y PVCT+++KA+PPCRS+C + K+ CE ++ KF F+WP+++ C+ +P + ++C+ N + + S P+ CP +L++P +K L + DCG PC Y F +FAR+W+ +WS +C STLFTV T+++DM+RF+YPERPIIFLS CY +V + Y+AG+FL DKV C N+ + K +VQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ ++DGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLE+L+ RIG+FSVLY VPA +VIAC+F+E +W + W ++ CK + P+ P + P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F+ RL Sbjct: 39 CQPITIPLCTDIAYNQTIMPNLVGHYNQDDAGLEVHQFYPLVKVQCSPELKFFLCSMYAPVCTVLEKAIPPCRSICERAKQGCEVLMNKFGFQWPEALRCEHFPVLGDGHICVGQNDSMATVSPVHMPIPGTPSVQLYSTPDKPFRCPSTLKVPAYLSYKF-LGE----PDCGAPCESSRTHRAYMFFTDQEIEFARIWILIWSSLCCASTLFTVTTYIVDMQRFKYPERPIIFLSGCYTMVSIAYIAGYFLGDKVVC-----NESFFPDSYKTIVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTISILAMGQIDGDVLSGVCFVGLNNSDALRGFILAPLFLYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACFFYEQAFRQQWEKSWISMN----------CKSLAIPCPMQPAPH-----MTPDFTVFMIKYLMTLIVGITSGFWIWSGKTLHSWQKFYVRL 540
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229]) HSP 1 Score: 490.73 bits (1262), Expect = 1.426e-165 Identity = 251/530 (47.36%), Postives = 343/530 (64.72%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKE--------------------SAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNR------YYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCR+LC + ++ CE ++ KF F+WP+ + C+ +P +C+ N+++ + N + +CP L +P ++ ++N CG PC YF E +R F R+WV +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY +V + Y AGF L DKV C F +D KT V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD LTGVC+ G+ + LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W++ CK+ P N P+F +FMIKYLM++IVGITSG WIWSGKTL SW+ F+ RL Sbjct: 45 CQPISIPLCTDIQYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSQDLKFFLCSMYAPVCTVLEQAIPPCRTLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNKSDPDVPTTNPTPYIPEPFSPRIHTPRQNQAFTCPLQLTVPSYLNYHFLGAKN-----CGAPCEHKQPYGLMYFKEEEVR-FGRLWVGIWSILCCVSTLFTVLTYLVDMRRFHYPERPIIFLSGCYFMVAVAYAAGFLLEDKVVCIDKF--RDDAFKT---VAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILALGQVDGDLLTGVCYVGIYNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHM----------QTCKRF-----AVPCPNNNFAPMTPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL 548
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Match: ntrk1 (neurotrophic receptor tyrosine kinase 1 [Source:Xenbase;Acc:XB-GENE-923001]) HSP 1 Score: 486.493 bits (1251), Expect = 7.319e-164 Identity = 246/529 (46.50%), Postives = 346/529 (65.41%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN---NLCIRDNQTEKESAPNVSLS--------------------CPKSLQIPVSYDFKIRLSQNSVIQDCGIPC-----NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRS+C + + CE ++ KF F+WP+ + C+ +P + +C+ N +E ++ S CP+ L++P +++ L + +DC PC + + F + +FARVW+ +WS +C ST FTV T+L+DM+RF+YPERPIIFLS CY +V + Y+AGF L DKV C N++ + K VVQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ ++DGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLE+L+ RIG+FSVLY VPA +VIACYF+E W + W CK + P+ P+F ++MIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 40 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSSELRFFLCSMYAPVCTVLEQAIPPCRSICERARHGCEALMNKFGFQWPERLRCENFPRHGAEQICVGQNHSEDGGPTLLTTSPPHHGTPGPPIYATLDHPFHCPRVLKVPSYLNYRF-LGE----KDCAAPCEPSKNDGFMFFSQDEIRFARVWILIWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLGDKVVC-----NENFSEDGYKTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNNIDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSW----------VSQNCKSLAIPCPLQYTPR-----MTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 543
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Match: bdh2 (3-hydroxybutyrate dehydrogenase 2 [Source:Xenbase;Acc:XB-GENE-985755]) HSP 1 Score: 484.182 bits (1245), Expect = 4.243e-163 Identity = 246/529 (46.50%), Postives = 349/529 (65.97%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESA-------------------PNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P +C+ N ++ + PN +CP+ L++P ++ L + +DCG PC YF E +R FAR+WV +W+ +C STLFTVLT+L+DM+RF YPERPIIFLS CY +V + Y AGF L ++ C F+ +DS + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD L+GVC+ G++ +LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSV+Y VPA +V+ACYF+E W + W L+ C+ + C ++ P++ P+F +FMIKYLM++IVGITS WIWSGKTL SW+ F+ RL Sbjct: 36 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDNSPSGPTARPTPYLPDSITFHPHPNRDFTCPRQLKVPPYLGYRF-LGE----KDCGAPCEPGKANGLMYFKEEEVR-FARLWVGIWAILCGISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYTAGFLLEERGVCVERFS-EDSY----RTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDILSGVCYVGINSVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVMYTVPATIVLACYFYEQAFRDTWEKTW-LVQTCKG--FAVPCPN-YNFAPMS-----------PDFTVFMIKYLMTMIVGITSSFWIWSGKTLQSWRRFYHRL 538
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Match: zdhhc9 (zinc finger DHHC-type containing 9 [Source:Xenbase;Acc:XB-GENE-1016830]) HSP 1 Score: 432.95 bits (1112), Expect = 6.191e-143 Identity = 241/550 (43.82%), Postives = 329/550 (59.82%), Query Frame = 3 Query: 60 FVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCT-IMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE----NNLCIRDNQTE-----------KESAPNVSLSCPKSLQIPV------SYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNP 1640 FV L ++ V C++I VP C+G+ Y T PN H TQDEA +E++++ PL+ I+C L+ FLCS+Y P+C +K LPPCRS+C + K C P+++K+ F WP+ M+CD PE + LC+ N TE K P+ + P S+ R+ V +C +PC + YF + + + FA W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACYL V + Y+ + ++ VAC + ++TG P + C ++F+L+YFF MAS+IWWV+LT TW+LAA W +E+I SQYFH AAW IP+ K+I +LALS VDGDP+ G+CF G + LRGF++APL +YL GT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIFSVLY VPA +V+ACY +E Y++ +K H+ PG +P++ +FM+KY M L+VGITSG+WIWSGKTL SWK F R C P Sbjct: 13 FVILLLDYFAPVRPASKAIVCQEITVPMCKGIGYNHTYMPNQFNHDTQDEAGMEVHQFWPLVVIQCSLDLKFFLCSMYTPICLPDYRKPLPPCRSVCERAKAGCSPLMRKYGFAWPERMNCDRLPEHGDPDTLCMDYNWTETTTTPPPTHPPKVKTPSSDCDGVCKCREPFLSITRESHPLYNRIKTGQV-PNCAMPCFQPYFTQ-DEKTFATFWIGLWSILCFISTFTTVATFLIDMERFRYPERPIIFLSACYLFVSIGYIVRLIVGHENVACNKDHIHYETTG--PAL---------CTVVFLLIYFFGMASSIWWVILTFTWFLAAGMKWGNEAIASYSQYFHMAAWLIPSVKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVVYLFTGTMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACYIYEQ-------------------HYREHWEKAHNCS--CPGDKK---RYRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWKRFTGRCCRNSKP 525
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Match: fzd8 (frizzled class receptor 8 [Source:NCBI gene;Acc:100038274]) HSP 1 Score: 423.705 bits (1088), Expect = 3.695e-139 Identity = 236/547 (43.14%), Postives = 329/547 (60.15%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE----NNLCIRD-NQTEKESAPNV--------SLSCPKSL------------------------QIPVSYDF-----KIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 +C++I VP C+ + Y T PN H TQDEA +E++++ PL+ I C L+ FLCS+Y P+C KK LPPCRS+C + + C P+++++ F WP M CD PE + LC+ N+TE+ +A + S PK +PV+ + ++R Q I +C +PC+ YF+ P R F W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACYL+V Y+ ++KVAC+ + I + T C ++F+L+YFF MAS+IWWV+L++TW+LAA W +E+I SQYFH AAW +P+ K+I +LALS VDGDP+ G+CF G + LRGF++APL IYL IG+ FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIFSVLY VPA +V+AC+F+E N Q W + C S + + + ++P++ +FM+KY M L+VGITSG+WIWSGKTL SW+ F +R C Sbjct: 26 SCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSAPKGRTRVEPPRPRPRAPGCEPGCQCRAPMVPVTNERHPLYNRVRTGQ---IPNCAMPCHNPYFS-PEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSAGYLVRLIAGHEKVACS-----RGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHN----RQGWEVAHNCNSCQPE------------------VAQPRRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTRCC 541
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Match: FZD9 (frizzled class receptor 9 [Source:NCBI gene;Acc:100487936]) HSP 1 Score: 397.127 bits (1019), Expect = 5.847e-129 Identity = 215/519 (41.43%), Postives = 307/519 (59.15%), Query Frame = 3 Query: 108 NQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCT-IMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENN----LCIR--DNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQD----------CG---IPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWK 1604 + CE I++P CQG+ Y MT PN++ H +Q+EAA ++ E+ PL+ CH L+ FLCSLY P+CT + ++P C+ +C +++C PI++ F + WP+S+ CD P N LC+ +N T + N P + + P I +S D C IP Y++ + + FA VW+A WS +C ST FTV TFL+ +RFQYPE+PIIFLS CY V Y F + + A P D G P ++ +G + C ++F++LY+F MAS++WWVVLT+TW+LAA W HE+I + YFH AAW IPA KTI IL + KV GD LTG+C+ G SDPS L GF++ PL YL+ GT FL+ GFV++F IR ++KTGG+ T+KLEKL+ +IG+FS+LY VPA +I C F+E +NL W R ++ C+ + P + + + P +FM+K MSL VGITSG+W+WS KTL +W+ Sbjct: 24 REAKCEPIQIPMCQGIGYNMTRMPNYVGHESQEEAAAKLQEFAPLVEYGCHIHLRFFLCSLYAPMCTEQVSTSIPACKPMCEAARQKCAPIMESFQYVWPESLDCDRLPSKNDPHALCMEAPENATNGDPPTNGHGMLPVAPRPPRPSGSGIGISSRCANPDKFMYVERSGVCAPRCIPGVDVYWSSGD-KDFALVWMAAWSGLCFISTAFTVFTFLLHPQRFQYPEKPIIFLSMCYNV----YSTAFLI--RAAAGAPSIACDREGGAPYLIREGLESSGCTLVFLILYYFGMASSLWWVVLTLTWFLAASKKWGHEAIESHGSYFHLAAWGIPAIKTIIILTMRKVGGDELTGLCYVGGSDPSALTGFVLVPLSCYLVTGTSFLLTGFVALFHIRRVMKTGGTNTEKLEKLMVKIGVFSILYTVPATCIIVCCFYERLNLAHWDSR----------AREESCRTV----PGSARPDCNLPHSIPSVAVFMLKIFMSLAVGITSGVWVWSSKTLQAWQ 521
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Match: Fzd1 (frizzled class receptor 1 [Source:MGI Symbol;Acc:MGI:1196625]) HSP 1 Score: 500.36 bits (1287), Expect = 3.676e-168 Identity = 262/556 (47.12%), Postives = 354/556 (63.67%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL--------------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP ++ C+ +P LC+ N ++K P SL SCP++L++P ++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY V + Y+AGF L D+V C F + + V QGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W + C+S Y C + G P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 98 NGERGISIP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDK-GTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGTVERGKFSCPRALRVPSYLNYHF-LGE----KDCGAPCEPTKVYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGA-----RTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSW-VAQSCKS--YAIPCPHLQGGG-----GVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 632
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Match: Fzd7 (frizzled class receptor 7 [Source:MGI Symbol;Acc:MGI:108570]) HSP 1 Score: 488.804 bits (1257), Expect = 1.108e-164 Identity = 254/540 (47.04%), Postives = 347/540 (64.26%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQ-----------TEKESAP-------------------NVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNR------YYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++ +A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P +C+ N T +AP + SCP+ L++P ++ L + +DCG PC YF E R+FAR+WV +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY +V + +VAGF L D+ C F++ + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD L+GVC+ GLS LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +V+ACYF+E W + W L+ C+S Y C H P++ P+F +FMIKYLM++IVGIT+G WIWSGKTL SW+ F+ RL Sbjct: 49 CQPISIPLCTDIAYNQTILPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLDQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDGSGGAGGSPTAYPTAPYLPDPPFTAMSPSDGRGRLSFPFSCPRQLKVPPYLGYRF-LGE----RDCGAPCEPGRANGLMYFKEEE-RRFARLWVGVWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAHVAGFLLEDRAVCVERFSDDGY-----RTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDLLSGVCYVGLSSVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVLACYFYEQAFREHWERTW-LLQTCKS--YAVPCPPGH-FSPMS-----------PDFTVFMIKYLMTMIVGITTGFWIWSGKTLQSWRRFYHRL 562
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Match: Fzd2 (frizzled class receptor 2 [Source:MGI Symbol;Acc:MGI:1888513]) HSP 1 Score: 476.478 bits (1225), Expect = 7.070e-160 Identity = 246/543 (45.30%), Postives = 343/543 (63.17%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPEN---NLCIRDNQTEK------ESAPNVSLS---------------------------CPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRS+C + ++ CE ++ KF F+WP+ + C+ +P + +C+ N +E +AP L CP+ L++P +K L + +DC PC +F++ R FAR+W+ WS +C ST FTV T+L+DM+RF+YPERPIIFLS CY +V + Y+AGF L ++V C F+ + VVQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ ++DGD L+GVCF GL+ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLE+L+ RIG+FSVLY VPA +VIACYF+E W + W CK + P + P+F ++MIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 44 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPSGLQPGAGGTPGGPGGGGSPPRYATLEHPFHCPRVLKVPSYLSYKF-LGE----RDCAAPCEPARPDGSMFFSQEETR-FARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGY-----RTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSW----------VSQHCKSLAIPCPAHYTPR-----MSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRL 560
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Match: Fzd5 (frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571]) HSP 1 Score: 423.705 bits (1088), Expect = 3.411e-139 Identity = 233/544 (42.83%), Postives = 326/544 (59.93%), Query Frame = 3 Query: 108 NQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP-----ENNLCIRDNQTEKESA-----------------PNVSLSCP---------KSLQIPVSYDF-----KIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 P C++I VP C+G+ Y +T PN H TQDEA LE++++ PL+ I C L+ FLCS+Y P+C K LPPCRS+C + K C P+++++ F WP+ MSCD P LC+ N++E +A P+ CP + +P+ + K+R Q + +C +PC + F+ P+ R FA W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACYL V L ++ + + VAC+ ++ P + C ++F+L+YFF MAS+IWWV+L++TW+LAA W +E+I +QYFH AAW IP+ K+I LALS VDGDP+ G+C+ G + ++LRGF++ PL +YLL+GT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIF++LY VPA +V+ACY +E + + W C PG +A KPE+ + M+KY M L+VGITSG+WIWSGKTL SW+ F SR C Sbjct: 29 KAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQ---VPNCAVPCYQPSFS-PDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPAL---------CTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQ----HYRESWEAALTCAC-----------------PGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRRFTSRCC 538
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Match: Fzd5 (frizzled class receptor 5 [Source:MGI Symbol;Acc:MGI:108571]) HSP 1 Score: 423.705 bits (1088), Expect = 3.411e-139 Identity = 233/544 (42.83%), Postives = 326/544 (59.93%), Query Frame = 3 Query: 108 NQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP-----ENNLCIRDNQTEKESA-----------------PNVSLSCP---------KSLQIPVSYDF-----KIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 P C++I VP C+G+ Y +T PN H TQDEA LE++++ PL+ I C L+ FLCS+Y P+C K LPPCRS+C + K C P+++++ F WP+ MSCD P LC+ N++E +A P+ CP + +P+ + K+R Q + +C +PC + F+ P+ R FA W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACYL V L ++ + + VAC+ ++ P + C ++F+L+YFF MAS+IWWV+L++TW+LAA W +E+I +QYFH AAW IP+ K+I LALS VDGDP+ G+C+ G + ++LRGF++ PL +YLL+GT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIF++LY VPA +V+ACY +E + + W C PG +A KPE+ + M+KY M L+VGITSG+WIWSGKTL SW+ F SR C Sbjct: 29 KAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFLCSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVLCMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPLYNKVRTGQ---VPNCAVPCYQPSFS-PDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRYPERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPAL---------CTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPVAGICYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTLLYTVPASIVVACYLYEQ----HYRESWEAALTCAC-----------------PGPDAGQPRAKPEYWVLMLKYFMCLVVGITSGVWIWSGKTLESWRRFTSRCC 538
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Match: sp|Q9I9M5|FZD1_XENLA (Frizzled-1 OS=Xenopus laevis OX=8355 GN=fzd1 PE=1 SV=1) HSP 1 Score: 503.056 bits (1294), Expect = 1.795e-169 Identity = 264/540 (48.89%), Postives = 357/540 (66.11%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENN---LCIRDNQTEKES-APNV--------------SLSCPKSLQIP--VSYDFKIRLSQNSVIQDCGIPC-----NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N + ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP+S+ C+ +P N LC+ N TE + P V CP++L++P V+Y F L + +DCG PC + + P FAR+W+ +WS +C STLFTVLT+L+DMKRF YPERPIIFLS CY +V + Y+AGF L DKV C F K V QGTK E C LFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD L+GVCF G+++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIGIFSVLY VPA +VIACYF+E +W + W + C++ Y C H P++ P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 38 NGEKGISIP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELKFFLCSIYAPVCTVLEQALPPCRSLCDRARQGCEALMNKFGFQWPESLRCEKFPINGAGELCVGQNTTESGTPTPAVPETWTSNSRTYYRDKFMCPRALKVPAYVNYHF---LGE----KDCGAPCEVGKVHGLMYFAPEELNFARIWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTMVAIAYIAGFLLEDKVVCNERFAEDGY-----KTVAQGTKKEGCTFLFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAVGQVDGDTLSGVCFVGINNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWEKSW-ISQSCKT--YAIPCPST-GHPPMS-----------PDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 549
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Match: sp|O57328|FZD1_CHICK (Frizzled-1 OS=Gallus gallus OX=9031 GN=FZD1 PE=2 SV=1) HSP 1 Score: 502.286 bits (1292), Expect = 8.965e-169 Identity = 262/550 (47.64%), Postives = 356/550 (64.73%), Query Frame = 3 Query: 87 RAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL---------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHD--HKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP ++ C+ +P LC+ N +E+ P +L SCP++L++P +++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DMKRF YPERPIIFLS CY V + Y+AGF L ++V C F S + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF G+++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIGIFSVLY VPA +VIACYF+E +W + W + C+S Y C H H P++ P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 60 RGISIP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLRCEKFPVHGAGELCVGQNASER-GTPTPALRPESWTSNPHRGGGAGGSGPGEARGRFSCPRALKVPSYLNYRF-LGE----KDCGAPCEPGRLYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMKRFSYPERPIIFLSGCYTAVAVAYIAGFLLEERVVCNERFAEDGS-----RTVAQGTKREGCTILFMMLYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGINNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWERSW-VTQSCKS--YAIPCPNNHSSHHPPMS-----------PDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 582
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Match: sp|Q9UP38|FZD1_HUMAN (Frizzled-1 OS=Homo sapiens OX=9606 GN=FZD1 PE=1 SV=2) HSP 1 Score: 502.286 bits (1292), Expect = 6.378e-168 Identity = 263/556 (47.30%), Postives = 355/556 (63.85%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL--------------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP ++ C+ +P LC+ N ++K P SL SCP++L++P ++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY V + Y+AGF L D+V C F + + V QGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W + C+S Y C + GG P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 103 NGERGISVP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDK-GTPTPSLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHF-LGE----KDCGAPCEPTKVYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGA-----RTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSW-VAQSCKS--YAIPCPHLQAG-----GGAPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 637
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Match: sp|O70421|FZD1_MOUSE (Frizzled-1 OS=Mus musculus OX=10090 GN=Fzd1 PE=1 SV=3) HSP 1 Score: 500.36 bits (1287), Expect = 2.571e-167 Identity = 262/556 (47.12%), Postives = 354/556 (63.67%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL--------------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + ++ CE ++ KF F+WP ++ C+ +P LC+ N ++K P SL SCP++L++P ++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY V + Y+AGF L D+V C F + + V QGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W + C+S Y C + G P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 98 NGERGISIP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDK-GTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGTVERGKFSCPRALRVPSYLNYHF-LGE----KDCGAPCEPTKVYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGA-----RTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSW-VAQSCKS--YAIPCPHLQGGG-----GVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 632
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Match: sp|Q08463|FZD1_RAT (Frizzled-1 OS=Rattus norvegicus OX=10116 GN=Fzd1 PE=1 SV=1) HSP 1 Score: 494.197 bits (1271), Expect = 5.786e-165 Identity = 262/556 (47.12%), Postives = 353/556 (63.49%), Query Frame = 3 Query: 78 NNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVSL--------------------------------SCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 N R ++ P + C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++ALPPCRSLC + + CE ++ KF F+WP ++ C+ +P LC+ N ++K P SL SCP++L++P ++ L + +DCG PC YF LR F+R W+ +WS +C STLFTVLT+L+DM+RF YPERPIIFLS CY V + Y+AGF L D+V C F + + V QGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD L+GVCF GL++ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W + C+S Y C + G P+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F++RL Sbjct: 98 NGERGISIP-DHGYCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVLEQALPPCRSLC-ERAQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDK-GTPTPSLLPEFWTSNPQHGGGGYRGGYPGGAGPVERGKFSCPRALRVPSYLNYHF-LGE----KDCGAPCEPTKVYGLMYFGPEELR-FSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSGCYTAVAVAYIAGFLLEDRVVCNDKFAEDGA-----RTVAQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVGLNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFRDQWERSW-VAQSCKS--YAIPCPHLQGGG-----GVPPHPPMSPDFTVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRL 631
BLAST of Fzd-1/2/7 vs. TrEMBL
Match: T1E1C6 (Fzd-1/2/7 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1250.73 bits (3235), Expect = 0.000e+0 Identity = 637/637 (100.00%), Postives = 637/637 (100.00%), Query Frame = 3 Query: 30 MLIKYFLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLXXXXXXXXXXXXXXXXXXKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 1940 MLIKYFLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM Sbjct: 1 MLIKYFLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 637
BLAST of Fzd-1/2/7 vs. TrEMBL
Match: T1E112 (Fzd-1/2/7 OS=Dendrocoelum lacteum OX=27895 PE=2 SV=1) HSP 1 Score: 982.63 bits (2539), Expect = 0.000e+0 Identity = 502/646 (77.71%), Postives = 556/646 (86.07%), Query Frame = 3 Query: 30 MLIKY--FLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKD-STGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHD-HKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLXXXXXXXXXXXXXXXXXXKPLLS-----NVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 1940 ML K+ FL + +FL +N AVNDPYNQ CEKIKV ACQGLLY MT+FPN M HSTQDEAA EINEY+PL+RIKCH SLQLFLCSLYFPVCT MK ALPPCRSLC IKK CEPILKKFYFKWP +M+CD YPENNLCI+DNQ EK+ +S+SCPK L++P SYDFK+R S NSVI DCGIPCNRY+FNEPNL+KF RVWVALWSF+CV STLFTVLTFLIDM+RFQYPERPIIFLSACYLVVGLTYVAGFFLND+VACAGPF+N D + PKIVVQGTKFESCII+FMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESI RNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDP+ L+GFLIAPLC+YLLIGT FLIAGFVSMFEIR+IIKTGG+KTDKLEKLITRIGIFSVLY+VPAVVVIACYFHESMNL+KWMQRW+ +D+CRS +Y+ C K D +K I P + + +QKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYF S+LCGRL G PWTRS WLE++N Y+QRHF G TANKM+I CDD Q + +QYQ QQ QQ+IG QELQKPLLS V E+++NAQ NGNLLP +QQIGD K QK+G+MM Sbjct: 3 MLFKWNIFLCIFLIFLTVN--EAVNDPYNQAKCEKIKVQACQGLLYDMTLFPNSMGHSTQDEAASEINEYLPLLRIKCHNSLQLFLCSLYFPVCTNMKIALPPCRSLCEDIKKSCEPILKKFYFKWPSNMACDKYPENNLCIKDNQAEKKPNETMSISCPKPLKVPPSYDFKVRYSSNSVIPDCGIPCNRYFFNEPNLKKFTRVWVALWSFLCVASTLFTVLTFLIDMQRFQYPERPIIFLSACYLVVGLTYVAGFFLNDRVACAGPFSNSDLRPNEVPKIVVQGTKFESCIIMFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIERNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPNALQGFLIAPLCLYLLIGTAFLIAGFVSMFEIRSIIKTGGTKTDKLEKLITRIGIFSVLYIVPAVVVIACYFHESMNLHKWMQRWFWVDVCRSPDYRKYCDKNVDLNKIIKPDSSMYLLNQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFLSKLCGRLEVGAPWTRSGWLERSNSYHQRHFAGLTANKMMINPCDDNQVMAMQYQMVQQNQQSIGNQELQKPLLSCHNGTGVTENMMNAQTLNGNLLPSNQQIGDPKNQKLGYMM 646
BLAST of Fzd-1/2/7 vs. TrEMBL
Match: A0A3Q0KT77 (Putative frizzled OS=Schistosoma mansoni OX=6183 PE=3 SV=1) HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0 Identity = 340/553 (61.48%), Postives = 417/553 (75.41%), Query Frame = 3 Query: 24 INMLIKYFLIVSFVFLFINNI--RAVNDPYNQ-PNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTG---KTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKI---HDHKPINPGGNAL------------IFS-----QKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWK 1604 + M ++ IV +F N R + DPY + P CE I++ ACQ L Y +TIFPN M H+TQD+AA EI +Y PL+R C SL+LFLCSL+FPVCT MKK LPPCRSLC Q +K+CEP+++ F+F+WP+ M+CD +PE++LCI +N+TEK + S CP +++P S++F++R+ +N +IQDCGIPC + F + + RKF+R+W+ LWSF+C ST FTVLTFLIDM RFQYPERPIIFLSACYL+V LTYVAGF LND VAC+GPF S + P++V QGTKFE CI+LFMLLYFFSMAS+IWWVVLTITWYLAAKCHWAHE+I RN+QY HFAAWAIPA KTIGILAL KVDGDPL+GVCFTGL+DP LR FLIAPLC+YLLIGT FL AGFVS+F+IRTIIKTGGSKTD LEKLI RIG+FS+LY+VPA+VVIACY HES KWM WY ++CR + I H + + G + IF+ +KPEFELFMIKYLM+L+VGITSG+WIWSGKTL+SWK Sbjct: 1 MAMCLRALFIVVHIFSHSNCYIQRGLEDPYAETPKCEPIRIKACQDLPYNITIFPNDMGHATQDDAAQEIGQYTPLVRTTCSSSLKLFLCSLFFPVCTGMKKPLPPCRSLCEQNRKDCEPLMRGFHFEWPKIMNCDRFPEDSLCIAENKTEKRPSKEPSFVCPVHMKVPPSFEFRVRMGRNQIIQDCGIPCGDFLFGDSSSRKFSRLWIGLWSFLCAASTSFTVLTFLIDMPRFQYPERPIIFLSACYLMVALTYVAGFILNDSVACSGPFPAPQSLSGQIEMPRLVTQGTKFEGCIVLFMLLYFFSMASSIWWVVLTITWYLAAKCHWAHEAISRNAQYLHFAAWAIPAAKTIGILALGKVDGDPLSGVCFTGLTDPVILRAFLIAPLCLYLLIGTCFLFAGFVSLFKIRTIIKTGGSKTDDLEKLIMRIGVFSLLYIVPALVVIACYLHESRMSEKWMLTWYTTEVCRKVDPNQLADSICPGHFKRLVEAGSSTSRSDNSDISVSQNIFAKIPALEKPEFELFMIKYLMTLVVGITSGVWIWSGKTLVSWK 553
BLAST of Fzd-1/2/7 vs. TrEMBL
Match: A0A075FFK0 (Frizzled-like protein OS=Schistosoma mansoni OX=6183 GN=Fz1 PE=2 SV=1) HSP 1 Score: 691.419 bits (1783), Expect = 0.000e+0 Identity = 340/551 (61.71%), Postives = 416/551 (75.50%), Query Frame = 3 Query: 30 MLIKYFLIVSFVFLFINNI--RAVNDPYNQ-PNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTG---KTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKI---HDHKPINPGGNAL------------IFS-----QKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWK 1604 M ++ IV +F N R + DPY + P CE I++ ACQ L Y +TIFPN M H+TQD+AA EI +Y PL+R C SL+LFLCSL+FPVCT MKK LPPCRSLC Q +K+CEP+++ F+F+WP+ M+CD +PE++LCI +N+TEK + S CP +++P S++F++R+ +N +IQDCGIPC + F + + RKF+R+W+ LWSF+C ST FTVLTFLIDM RFQYPERPIIFLSACYL+V LTYVAGF LND VAC+GPF S + P++V QGTKFE CI+LFMLLYFFSMAS+IWWVVLTITWYLAAKCHWAHE+I RN+QY HFAAWAIPA KTIGILAL KVDGDPL+GVCFTGL+DP LR FLIAPLC+YLLIGT FL AGFVS+F+IRTIIKTGGSKTD LEKLI RIG+FS+LY+VPA+VVIACY HES KWM WY ++CR + I H + + G + IF+ +KPEFELFMIKYLM+L+VGITSG+WIWSGKTL+SWK Sbjct: 1 MCLRALFIVVHIFSHSNCYIQRGLEDPYAETPKCEPIRIKACQDLPYNITIFPNDMGHATQDDAAQEIGQYTPLVRTTCSSSLKLFLCSLFFPVCTGMKKPLPPCRSLCEQNRKDCEPLMRGFHFEWPKIMNCDRFPEDSLCIAENKTEKRPSKEPSFVCPVHMKVPPSFEFRVRMGRNQIIQDCGIPCGDFLFGDSSSRKFSRLWIGLWSFLCAASTSFTVLTFLIDMPRFQYPERPIIFLSACYLMVALTYVAGFILNDSVACSGPFPAPQSLSGQIEMPRLVTQGTKFEGCIVLFMLLYFFSMASSIWWVVLTITWYLAAKCHWAHEAISRNAQYLHFAAWAIPAAKTIGILALGKVDGDPLSGVCFTGLTDPVILRAFLIAPLCLYLLIGTCFLFAGFVSLFKIRTIIKTGGSKTDDLEKLIMRIGVFSLLYIVPALVVIACYLHESRMSEKWMLTWYTTEVCRKVDPNQLADSICPGHFKRLVEAGSSTSRSDNSDISVSQNIFAKIPALEKPEFELFMIKYLMTLVVGITSGVWIWSGKTLVSWK 551
BLAST of Fzd-1/2/7 vs. TrEMBL
Match: C6ZDD0 (Frizzled 7 OS=Schistosoma japonicum OX=6182 PE=2 SV=1) HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0 Identity = 335/553 (60.58%), Postives = 418/553 (75.59%), Query Frame = 3 Query: 24 INMLIKYFLIVSFVFLFINNI--RAVNDPYNQ-PNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTG---KTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKI---HDHKPINPGGNAL------------IFS-----QKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWK 1604 +++ ++ +IV+ +F N R + DPY + P CE I++ ACQ L Y +TIFPN M H+TQD+AA EI +Y PL+R C SL+LFLCSL+FPVCT MKK LPPCRSLC Q +K+CEP+++ F+F+WP+ M+CD +PE++LCI +N+TEK + S CP +++P S++F+IR+ N VI DCGIPC+ + F + + R+F+R+W+ LWS +C STLFTVLTFLIDM RFQYPERPIIFLSACYL+V LTYVAGF LN++VAC+GPF S + P+++ QGTKFE CI+LFMLLYFFSMAS+IWWVVLTITWYLAAKCHWAHE+I RN+QY H AAWAIPA KTIGILAL KVDGDPL+GVCFTGL+DP LR FLIAPLC+YLLIGT FL AGFVS+F+IRTIIKTGGSKTD LEKLI RIG+FS+LY+VPA+VVIACY HES KWM WY ++CR + I H + + + IF+ ++PEFELFMIKYLM+LIVGITSGIWIWSGKTL+SW+ Sbjct: 1 MHLTLRVLVIVAHIFSHSNCYVQRGLEDPYAETPKCEPIRIKACQDLPYNITIFPNDMGHATQDDAAQEIGQYTPLVRTTCSSSLKLFLCSLFFPVCTGMKKPLPPCRSLCEQNRKDCEPLMRGFHFEWPEIMNCDRFPEDSLCIAENKTEKRVSKEPSFVCPVHMRVPPSFEFRIRMGSNQVIHDCGIPCDDFLFGDSSSRRFSRLWIGLWSCLCAASTLFTVLTFLIDMPRFQYPERPIIFLSACYLMVALTYVAGFILNNEVACSGPFPAPQSLSGQIEMPRLITQGTKFEGCIVLFMLLYFFSMASSIWWVVLTITWYLAAKCHWAHEAISRNAQYLHSAAWAIPAAKTIGILALGKVDGDPLSGVCFTGLTDPVILRAFLIAPLCLYLLIGTCFLFAGFVSLFKIRTIIKTGGSKTDDLEKLIMRIGVFSLLYIVPALVVIACYLHESRMSEKWMLTWYTTEVCRKVDPNQLADSICPGHFRRLVEASSSTSRSDNSDGSISENIFAKISALERPEFELFMIKYLMTLIVGITSGIWIWSGKTLVSWQ 553
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229]) HSP 1 Score: 493.041 bits (1268), Expect = 1.869e-166 Identity = 252/529 (47.64%), Postives = 346/529 (65.41%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKES--------APNVS-----------LSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNR------YYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + + CE ++ KF F+WP+ + C+ +P +C+ N ++ S AP ++ +CP L +P ++K ++ DCG PC YF E + KF R+WV +W+ +C STLFTVLT+L+DM+RF+YPERPIIFLS CY +V + YV GF L DKV C F +D+ + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILAL +VDGD LTGVCF G+ + LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E +W + W++ CK+ P ++ P+F +FMIKYLM++IVGITSG WIWSGKTL SW+ F+ RL Sbjct: 50 CQPISIPLCTDIQYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSADLKFFLCSMYAPVCTVLEQAIPPCRSLCERARHGCEALMNKFGFQWPERLRCEAFPVHGAGEICVGQNTSDPGSPTSEPTLYAPGLTPPPGPERSGQPFTCPLQLAVPSYLNYKFLGAK-----DCGAPCEHSQPHGLMYFREEEM-KFGRLWVGIWAILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYVTGFLLEDKVVCIDKF-REDAY----RTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILALGQVDGDLLTGVCFVGIYNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREQWEKTWHM----------QTCKRF-----AVPCPSSNFAPMSPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRSFYKRL 552
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Match: FZD7 (frizzled-7-A-like [Source:NCBI gene;Acc:103021589]) HSP 1 Score: 483.411 bits (1243), Expect = 1.085e-162 Identity = 251/543 (46.22%), Postives = 341/543 (62.80%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEK-------ESAPN--------------------------VSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPC------NRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + + CE ++ KF F+WP+ + C+ +P +C+ N +E S P +CP L++P ++ + DCG PC YF E + KF R+WV +WS +C STLFTVLT+L+DM+RF+YPERPIIFLS CY +V + Y AGFFL D+V C F++ + V QGTK E C ILFM+LYFF MAS+IWWVVL++TW+L+A W HE+I N+QYFH AAWA+PA KTI ILAL +VDGD L GVC+ G+ LRGF++APL +YL +GT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA VVIACYF+E +W + W++ CK+ P G A + P+F +FMIKYLM++IVGITSG WIWSGKTL SW+ F+ RL Sbjct: 45 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSADLKFFLCSMYAPVCTVLEQAIPPCRSLCERARHGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSEAAGGGAGATSEPTGYGREPLTLPPGAGGAGGIGSGGKSSPHFTCPLQLRVPSYLNYHFMGEK-----DCGAPCEPTKPNGLMYFREEEV-KFGRLWVGIWSVLCCASTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYAAGFFLEDRVVCIDRFSDDGY-----RTVAQGTKKEGCTILFMILYFFGMASSIWWVVLSLTWFLSAGMKWGHEAIEANAQYFHLAAWAVPAVKTITILALGQVDGDVLAGVCYVGVHSVDALRGFVLAPLFVYLFLGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATVVIACYFYEQAFRPQWERTWHM----------HTCKRF--AVPCPAGDFAPV---TPDFTVFMIKYLMTMIVGITSGFWIWSGKTLQSWRRFYKRL 561
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Match: ENSAMXT00000026985.2 (pep primary_assembly:Astyanax_mexicanus-2.0:19:27065879:27070162:-1 gene:ENSAMXG00000026259.2 transcript:ENSAMXT00000026985.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 424.476 bits (1090), Expect = 1.486e-139 Identity = 228/533 (42.78%), Postives = 320/533 (60.04%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRDNQTEKES-APNVSLSCPKSLQ---------IPVSYDFKIRLS-----------------QNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSR 1619 CE I VP C+G+ Y +T PN H TQ+E LE++++ PL+RI+C L FLCS+Y P+C KK LPPCRS+C + K+ C P++ ++ F+WP+ MSC+ P + LC+ N +E + +P+ P+ +P D + R Q + +C +PC++ YF++ + R F W+ LWS +C STL TV TFLIDM+RF+YPERPIIFL+ACYL V L Y+ ++KVAC G +G I+ T C ++F+L+YFF MAS+IWWVVL+ TW+LAA W +E+I SQYFH AAW +P+ K+I +LALS VDGDP+ G+C+ G +LRGF++APL +YL G+ FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIG+F+VLY VPA +V+AC +E +W Q C + + P++ +FM+KY M L+VGITSG+WIWSGKTL SW+ F +R Sbjct: 37 CEPITVPMCKGIGYNLTYMPNQFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYKKPLPPCRSVCERAKRGCSPLMIQYGFEWPERMSCEQLPMLGDPDRLCMDQNSSETTTLSPSFPKPTPRGSSRHRATSKSAVPQKCDRECRCREPLVPIKKESHPLYNRVQTGSLPNCALPCHQPYFSQ-DERAFTTFWIGLWSVLCFVSTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIVRLLAGHEKVACGG-------SGDQRHILYDTTGPALCTLVFLLIYFFGMASSIWWVVLSFTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLESLRGFVLAPLVVYLFSGSLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGLFTVLYTVPATIVVACLVYEQHYRPEWEQ-----------ALGCSCASERQQQGLG-----------PDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRRFVAR 539
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Match: fzd9a (frizzled class receptor 9a [Source:ZFIN;Acc:ZDB-GENE-060531-77]) HSP 1 Score: 390.963 bits (1003), Expect = 2.036e-126 Identity = 222/541 (41.04%), Postives = 312/541 (57.67%), Query Frame = 3 Query: 81 NIRAVNDPYNQP-NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENN----LCIR--DNQT--------------EKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYY--FNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTY----VAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSR 1619 +I A + +P CE I +P CQG+ Y MT PN M + +Q+EA++++NE+ PL+ C L+ FLCSLY P+CT + +P CR++C+Q +++C PI+++F F WP S+ C P NN LCI +N T + P P K + + S + C C+ F + FA +W+ +WS +C ST FTVLTFL+D +RFQYPERPIIFLS CY V + + VAG + +AC D I+ +G + C I+F++LY+F MAS+IWWV+LT+TW+LAA W HE+I +S YFH AW IPA KTI IL + KV GD LTG+C+ G D + L GF+I PL YL+IGT F++ GFV++F IR I+KTGG+ T+KLEKL+ +IG+FS+LY VPA VI CYF+E +N+ W R + +C P + + S P +FM+K MSL+VGITSG+W+WS KTL +W+ +R Sbjct: 37 DIGAYDGERGRPAKCEPITIPMCQGIGYNMTRMPNFMKYESQEEASIKLNEFAPLVEYGCDVHLRFFLCSLYVPMCTDQVSTTIPACRAMCVQARQKCSPIMEQFSFGWPDSLDCSKLPTNNDPNALCIEAPENDTVPPTKKGEGMLPVPARPRPPGTGAGRPSGGSGSCENHEKFQYVEKS--ESCAPRCSPTVDVFWSRQDKDFAFIWMVVWSTLCFVSTAFTVLTFLLDPQRFQYPERPIIFLSMCYNVYSVAFIIRSVAG---AENIAC-------DRENGQLYIIQEGLESTGCTIVFLILYYFGMASSIWWVILTLTWFLAAGRKWGHEAIEAHSSYFHMVAWGIPAMKTIVILTMRKVAGDELTGLCYVGSMDTNALTGFIIIPLSCYLIIGTSFILTGFVALFHIRKIMKTGGTNTEKLEKLMVKIGVFSILYTVPATCVIICYFYERLNMDYWKFR----------ASESKCVSF----PGRRTEDCTLDSSVPTVAVFMLKIFMSLVVGITSGVWVWSSKTLQTWQGLCAR 551
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3]) HSP 1 Score: 384.415 bits (986), Expect = 1.833e-124 Identity = 222/540 (41.11%), Postives = 313/540 (57.96%), Query Frame = 3 Query: 51 IVSFVFLFINNI-RAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALP---PCRSLCLQIKKE----CEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIP-VSYDFKIRLSQNSV----IQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 I F+FL + + R+ + C++I VP C+G+ Y T PN H TQDEA LE++++ PL+ I+C L+ FLCS+Y P+C KK LP +LC+ + P+L K + + + P R + P + P V + + N V + +C +PC+ YF + + R F W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACY+ V + Y+ ++KVAC+ + + + T C ++F+L+YFF MAS+IWWV+L++TW+LAA W +E+I SQYFH AAW IP+ K+I +LALS VDGDP+ G+C+ G + LRGF++APL IYL IGT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIF+VLY VPA +++ACYF+E N W E C + +H+ ++P++ +FM+KY M L VGITSG+WIWSGKTL SW+ +R C Sbjct: 8 IYLFLFLALGTLQRSSGTTAKELTCQEIAVPLCKGVGYNHTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLRFFLCSMYTPICLEDYKKPLPVQGDPDTLCMDYNRTDSTTASPVLSKPTGRPGKP---HVPPHRTKHGRPGVQPPKRKPGSPCDPGCQCRAPMVRVNSERHPLYNRVKTGQMPNCAMPCHNPYFTQ-DERTFTAFWIGLWSVLCFVSTFATVATFLIDMERFKYPERPIIFLSACYMFVSIGYIVRLIAGHEKVACSREY-------DVEHVHYETTGPALCTVVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYSQYFHLAAWLIPSMKSIAVLALSSVDGDPVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTVLYTVPATIIVACYFYEQHNRQSW-------------ETSHNCSCLMEHE-----------LRRPDYAVFMLKYFMCLSVGITSGVWIWSGKTLDSWRALCTRCC 512
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224]) HSP 1 Score: 490.345 bits (1261), Expect = 1.641e-166 Identity = 260/556 (46.76%), Postives = 351/556 (63.13%), Query Frame = 3 Query: 87 RAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNVS-----------------------------------LSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 RA++ P C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT+++KA+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P + +C+ N T+K + CP+ L++P + ++ +N C PC YF+E LR F+R+WV +WS +C STLFTV T+L+DM+RF+YPERPIIFLS CY +V + YVAGF L+DKV C N+ + + V QGTK E C ILFML+YFFSMAS+IWWVVL +TW+LAA W HE+I NSQYFH AAWAIPA KTI ILA+ VDGD L+GVCF G+S + LRGF++APL +YL +GT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIGIFSVLY VPA +VIACYF+E +W + W CK P+N N KP+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F+++L Sbjct: 3 RAISVP-EHGFCQPISIPLCTDIPYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCTVLEKAIPPCRSLCDRARQGCEALMNKFGFQWPERLRCENFPVQGSDEICVGQNHTDKAGPTALPPTPPGGGGGVIGGIGGGAGDFVTIHTRRPPGRTHPFMCPRVLKVPPYLNAQLFRERN-----CAAPCEPKKPNGLMYFSEEELR-FSRLWVGIWSVLCCASTLFTVTTYLVDMQRFRYPERPIIFLSGCYFMVAVAYVAGFLLDDKVVC-----NEQFSEDIYRTVTQGTKKEGCTILFMLIYFFSMASSIWWVVLALTWFLAAGMKWGHEAIEANSQYFHLAAWAIPAVKTITILAMGLVDGDMLSGVCFVGISSVAALRGFVLAPLFVYLFLGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFREQWEKTW----------VSQSCKGFAIPCPLNHYPN-----MKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTKL 531
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Match: fzd7a (frizzled class receptor 7a [Source:ZFIN;Acc:ZDB-GENE-990415-223]) HSP 1 Score: 490.345 bits (1261), Expect = 1.152e-165 Identity = 260/561 (46.35%), Postives = 355/561 (63.28%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP---ENNLCIRDNQTEKESAPNV----------------------------------------------SLSCPKSLQIP--VSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGR 1631 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P N+C+ N T+++ L+CP L++P ++Y F + ++CG PC YF+ L FAR+WV +WS +C STLFTVLT+L+DM+RF+YPERPIIFLS CY VV + Y+ GFF +K+ C F + ST VVQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD LTGVCF GL+ LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIGIFSVLY VPA +VIACYF+E +W + W + C+S + +C + H P + KP+F +FMIKYLM+LIVGITSG WIWSGKTL SW+ F+SRL + Sbjct: 57 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPDLKFFLCSMYAPVCTVLEEAIPPCRSLCERARQGCETLMNKFGFQWPERLRCENFPVQGSENICVGQNHTDEKGGHPTPPDPHPIPHGDSFTLPPHYRPGGPSSGGGIGGGGGGGASGGDSSSYQLTCPHVLRVPSYLNYQFLGK-------KECGSPCEPSKSNGLMYFDADELW-FARMWVGVWSILCCASTLFTVLTYLVDMERFRYPERPIIFLSGCYAVVSIAYIVGFFFEEKIVCNKFFEDSYST------VVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGLNSIDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGIFSVLYTVPATIVIACYFYEQAFRAQWEKSW-VAHTCKS--FAVQCPQ--GHYP----------NMKPDFTVFMIKYLMTLIVGITSGFWIWSGKTLQSWRNFYSRLSNK 588
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011009.1 (pep scaffold:Pmarinus_7.0:GL485859:2701:4509:1 gene:ENSPMAG00000009982.1 transcript:ENSPMAT00000011009.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 399.823 bits (1026), Expect = 1.565e-130 Identity = 223/549 (40.62%), Postives = 318/549 (57.92%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRDNQTE--------KESAPNVSLSCPK-------------------------SLQIPV------SYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIK-TGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCG 1628 C+ I VP C+G+ Y T PN H +QDEA LE++++ PL+ IKC L+ FLCS+Y P+C K+ LPPCRS+C + + C P+++++ F WP M CD P +N LC+ N+++ K +AP S + K + + P+ + R+ SV+ +C +PC+ YF + + R FA W+ LWS +C ST TV+TFLIDM+RF+YPERPIIFLSACY V + Y+ + +D V C + P + C ++F+L YFF MAS+IWWV+L++TW++AA W+ E+I SQY+H AAW +P+ +++ +LA S VD DPL G+C G LRGF++ PL +YL +G FL+AGF S+ IR IK GG+KTDKLEKL+ RIGIFS+LY VPA+ V+ACYF+E + W + IC S + D +P G+ Q+P++ +FM+KY M L+VGITSG+WIWSGKT+ +WK R CG Sbjct: 9 CQNITVPMCRGIGYNHTYMPNDFNHDSQDEAGLEVHQFWPLVEIKCSPDLRFFLCSMYTPICLEDYKQPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPVLGDQNRLCMDYNKSDTTPQPPEVKPTAPVRSFNPSKNRATTRVGGGGGGGGGSGEACESGCACRAPMVAIGSDRHPLYNRVRTGSVL-NCAMPCHDPYFTQ-DERTFASFWIGLWSILCFVSTFTTVVTFLIDMERFKYPERPIIFLSACYAFVSMGYIVRLVVGHDGVICNQEHRHVHYETTGPAL---------CTVVFLLTYFFGMASSIWWVILSLTWFMAAGMKWSSEAIAGYSQYYHLAAWLLPSVQSVAVLATSSVDADPLAGICSVGAQSLENLRGFVLVPLTVYLCVGAVFLLAGFTSLVRIRNAIKQQGGTKTDKLEKLMVRIGIFSMLYTVPAIAVVACYFYEERSRDGWARAL----ICPSCQ--------GDEEP----GSQQQQQQRPDYGIFMLKYFMCLVVGITSGVWIWSGKTVDTWKRLCCRCCG 530
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3]) HSP 1 Score: 284.648 bits (727), Expect = 3.621e-89 Identity = 161/384 (41.93%), Postives = 225/384 (58.59%), Query Frame = 3 Query: 477 APNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKT--GGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSR 1619 AP V +S P+ V YD ++R Q +++C PC+ + R FA W+ LWS +C +T TV TFLIDM+RF+YPERPIIFLS C ++ L Y+ ++ VAC+ + + P + C +F+L YFF MA +WWV+L++TW++AA W E+I SQY+H AAW +P+ K I LA++ VDGDP+ G+C G LRGF++APL YLL+GT FL+AG V++F IR I GG+KT+KLE+L+ RIG+F+VLY VPA V + C+ +E + W + +C C H P PG +P+F +FM+KY + L+ GITSG WIWSGKT SWK F+ R Sbjct: 9 APLVRISNPRH----VLYD-RVRTGQ---VRNCATPCHSPFLGREQ-RTFASFWIGLWSSLCFAATFATVSTFLIDMERFKYPERPIIFLSLCCMLASLGYIVRMVAGHEAVACSADWHHVLYASSGPAL---------CTAVFLLTYFFGMAGCVWWVILSLTWFMAAGLKWGSEAIAGYSQYYHLAAWLLPSIKAIAALAMNAVDGDPVAGICSVGNQSLDNLRGFVLAPLVAYLLVGTAFLLAGLVALFRIRNAISANPGGAKTEKLERLMVRIGVFAVLYTVPAAVAVVCHLYEQQHRDSWER----TLVC------GACGPGPGHLP-EPG-------ARPDFAVFMLKYFVCLVGGITSGAWIWSGKTAGSWKRFYKR 356
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Match: fzd3b (frizzled class receptor 3b [Source:ZFIN;Acc:ZDB-GENE-070122-1]) HSP 1 Score: 229.95 bits (585), Expect = 1.232e-67 Identity = 153/375 (40.80%), Postives = 215/375 (57.33%), Query Frame = 3 Query: 498 CPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVA-CAGPFTNKDSTGKTPKIVVQGTKF-ESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFS 1616 CP+ L++P + + DC PC YF+ L + R V + S +C+ +T FT LTFL+D KRF+YPERPIIF + CY+ V L+++ GF L+D A C P + G V QG++ ++C +FMLLYF +MA A+WWVVLTITW+LAA W E+I + + FH AW PA T+ +LAL+KV+GD L+GVC+ GL D +TLR F++APL G L+AG VS+ +R ++ G KL K + RIG+FSVLY+VP + ++AC +E + W W L D C EY+ C ++P Q+P LF++KY +L+VGI W+ S KT L W F S Sbjct: 10 CPRELKVPSGLGYSFM-----GVPDCSPPCPNMYFSSGEL-ELTRYLVGVMSVVCLVATTFTFLTFLLDRKRFRYPERPIIFYATCYVAVSLSFLVGFLLDDSAAACNAPGLAPGAAG----TVTQGSRNNKACTAVFMLLYFSAMAGALWWVVLTITWFLAAGLKWGREAIEKRAAAFHALAWGPPAALTVALLALNKVEGDNLSGVCYAGLYDVTTLRYFVLAPLGACAAAGLSLLLAGIVSLNRVRLEMRHDGRNQTKLVKFMVRIGVFSVLYLVPQLALVACLVYEQASRAAWEATW-LRDRC--TEYRIPC-PYQANQP----------KQRPALVLFLVKYFTTLVVGIPPAFWVGSRKTCLGWAAFLS 360
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Match: EDO35751 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKM6]) HSP 1 Score: 487.263 bits (1253), Expect = 5.963e-165 Identity = 250/527 (47.44%), Postives = 343/527 (65.09%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE--NNLCIRDNQTEKESA----------PNVSLS-----CPKSLQIP-VSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLY----KWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGR 1631 CE + +P C GL Y MTIFPN + H TQ+EAALE++++ PL+++ C L FLCS+Y PVCT+++ LPPCRSLCL ++ CE ++K+F F WP S+SC+ +P+ + +C+ +N T S P+V +S CP+S +IP Y F + C C +F + R+ AR+W +W+ +C STLFT+LTFLIDM+RF+YPERPIIFLS CY +V + ++ G+ DK+AC P PK +VQGTK E C ++FM+LYFFSMAS+IWWV+LT+TW+LAA W E+I NSQ+FH AAWAIPA KTI IL ++KVDGD L+GVC+ GLSD S LRG+++APL +Y +IG FL+AGF+S+F +R+++K SK +K+EKL+ RIG+FS+LY VPA+VVI C ++E N W++ W C E K + + P+ QKP+F +FM+KYLM LIVGITSG WIWS KTL SW+ F+ R R Sbjct: 28 RCEPVTIPLCTGLQYNMTIFPNTLKHRTQEEAALEVHQFFPLVKVDCSKDLAFFLCSVYAPVCTVLETPLPPCRSLCLTVRSGCEGLMKRFGFTWPDSLSCERFPKLGDEICVGENTTTPTSDQDGGINNNTYPDVDMSTMRYRCPESQKIPNDQYTFHGE-------KRCAATCRNVFFTKRE-REIARMWTGIWAILCAVSTLFTILTFLIDMRRFRYPERPIIFLSGCYFMVSIAFITGYVAGDKIACNEPIKKG-----FPKTLVQGTKHEGCTVIFMMLYFFSMASSIWWVILTVTWFLAAGLKWGQEAIEANSQFFHLAAWAIPAVKTIAILLMTKVDGDELSGVCYVGLSDVSALRGYVLAPLFVYFIIGATFLLAGFISLFRVRSVLKDDYSKREKIEKLMIRIGVFSILYTVPALVVIGCLYYEQSNRELWDNSWIEGWKRQKKCTEVETKLKGEVSCPPYPVP--------LQKPDFMVFMVKYLMFLIVGITSGFWIWSSKTLNSWRRFYRRFILR 533
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Match: EDO42932 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S003]) HSP 1 Score: 390.578 bits (1002), Expect = 1.941e-127 Identity = 227/566 (40.11%), Postives = 327/566 (57.77%), Query Frame = 3 Query: 18 LAINMLIKYFLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIM-KKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE----NNLCI-RDNQTEKESAPN-------------VSLSC----PKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDK-VAC-AGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGS-KTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLN 1637 +A L + F+ V+F+ +N + + CE+I +P C+G+ Y +T PN H TQ EAALE++++ PL+ I+C L+ FLCS+Y P+C K LPPCRS+C + + C P+++K+ F WP+ M C+ +PE N LC+ R++ E P+ +S +C P + I R + C + CNR YF + FA W+ LW+ +C STL T LTFL+DM RF+YPERPIIFLS CYL+V + Y+ K +AC + D++G SC I+F+L+YFF MAS++WWV+L TW+L+A W+ E+I SQYFH AW +PA + I +LA+S +DGDP++G+C+ G + +L F+I PL +YL+ GT FL+AGF S+ IR +++ GS KTDKLEKL+ RIG+FSVLY VPA +V+ACY++E +N W + IN G + KP+ +F+IKY M+L+VGITSG WIWSGKT+ SW+ F +RL G N Sbjct: 1 MATRRLDRVFVAVAFISC-LNYVLT-----KEMKCEEITIPMCRGIGYNLTYMPNMFNHDTQAEAALEVHQFWPLVEIQCSPDLRFFLCSMYAPLCEKHYDKDLPPCRSVCERARTGCAPLMRKYGFSWPERMKCENFPELGDENTLCMGRNSSGESTPKPSQSPQPAPSPDTAAISANCCSCRPPFVSIAGKNIKPTRAISVGGVPQCAMACNRTYFTH-DQDSFASFWIGLWAILCFISTLVTTLTFLVDMHRFKYPERPIIFLSGCYLMVSVGYIIRLIAGHKQIACDSNGLMRYDTSGPA-----------SCTIVFLLVYFFGMASSVWWVILAFTWFLSAGMKWSSEAITNYSQYFHAVAWLVPAIQAIAVLAMSTIDGDPVSGICYVGNHNLQSLVVFVIVPLVVYLVFGTSFLMAGFYSLVRIRKLLRQHGSTKTDKLEKLMIRIGVFSVLYTVPATIVVACYYYELVNRETW------------------------ERTINCSGCG-VTRVKPDHSVFIIKYFMALVVGITSGFWIWSGKTIESWRNFCARLSGTQN 523
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Match: EDO38567 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCF4]) HSP 1 Score: 365.54 bits (937), Expect = 4.679e-117 Identity = 208/530 (39.25%), Postives = 295/530 (55.66%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKE------SAPNVSLSCP----------KSL-----QIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQG----TKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRW-YLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCG 1628 C I +P C G+ Y T FPN + +Q+EAA I+E+ PL+ + C L+ FLCS++ P+CT + + CRS+C + C P++++F F WP ++ CD P+ D Q + + +APN+ + P +SL +I + + + + C C N ++FA VW+++WS +C ST TVLTF+ID RF+YPERPIIFLS CY + L Y+ AG N+ +T V++ C ++F+LLY+F MASA+WWVVLT W+LAA W E+I R + YFH AW +PA +TI L + KVD D LTG+C+ G D L +++ PLC+YLL+GT FL+AGFVS+F IRT++K + TDKLEKLI RIG+FSVLY +P VIAC F+E N+ W R + ICR G A + + P E+F++KY M LI+GITS +WIWS KT SW+ F+S+ G Sbjct: 32 CTPITIPLCMGIGYNATRFPNFLAQESQEEAAKRIHEFKPLIAVNCAPLLRFFLCSVFVPMCTKEVNVPIYACRSMCESARDGCSPMMQRFGFNWPDTLDCDRLPKKG----DPQAKSDPTKLCMAAPNIKQTAPLNESDIWSNFESLGPEFKKINNTGPLRYKYTYVEKYDQCVPQCKSDLMFSSNNKRFANVWISVWSVLCFISTAVTVLTFVIDTSRFKYPERPIIFLSLCYNLYSLGYIVR-------VTAG--RNEVICDETESFVIRAGMNIADHACCSVVFLLLYYFGMASAVWWVVLTFAWFLAAGRKWGQEAIERKATYFHAVAWTVPAIQTIMALIMRKVDADELTGLCYVGNMDYENLANYVLTPLCLYLLVGTFFLLAGFVSLFRIRTVLKNKETNTDKLEKLIVRIGVFSVLYTIPVSAVIACSFYEYNNMDVWKVRAPFNTYICR-------------------GDQACLENYGPSIEVFIVKYFMLLIIGITSNMWIWSTKTFKSWRKFYSKRKG 529
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Match: EDO30865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZJ6]) HSP 1 Score: 311.997 bits (798), Expect = 9.880e-98 Identity = 193/525 (36.76%), Postives = 284/525 (54.10%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKC-HGSLQLFLCSLYFPVCT-IMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLY----PENNLCIRD---NQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNS-------VIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDK-VACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGG-SKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNP 1640 CEKI + C+ + Y +T PN + H TQ EA ++ +++PL++ C L FLCS Y P+CT + + CR LC ++K C P+L +F WP ++C + E N+C+ ++ ++ P+ + + P + + R +NS + C + CN + + ++ +W+ +WS C ST T+ TFLI+ RF+YPER II+L+ CY L+Y+ + ++C + D T + G + C I+F++ YFF MA+ IWWVVL +TW+LAA W E+IG ++ FH AW +P KTI IL KVDGD LTG+CF G D L F++ P YL+IGT FLIAGFV++F IRT ++ GG +KTDKLE+LI RIGIFSVL VPA VIACYF+E N + WY G +P F +FM+K MSL G+ +G+WIWS KT+ +W+ F+ ++ G+ P Sbjct: 4 CEKISIDLCRSVGYNVTRMPNLIGHETQKEAESQLKQFLPLIQYGCAREQLVFFLCSAYAPMCTDKVDVVITSCRPLCEYVRKSCLPVLTEFGIPWPNPLNCTRFLVRNNERNMCMPGPNFTESPEKPRPDFKPINDTTEKPPSTGSEQCRRFKNSKNYFYVQSTESCAVRCNEDGIFKTSDKETMDIWITIWSIFCFISTTITLTTFLIETGRFKYPERSIIWLALCYNFYSLSYIIRLGAGRQAISC-----DTDPTTHVKFHIQDGLRNTGCAIVFLIQYFFCMAATIWWVVLALTWFLAAGMKWGCEAIGSYAKLFHIIAWILPCIKTIFILITRKVDGDELTGLCFVGNQDLIALAAFVLGPQFTYLIIGTLFLIAGFVALFRIRTTVQRGGQAKTDKLERLIVRIGIFSVLSTVPATAVIACYFYEYAN----KEYWYY-------------------------GQRDGAVAEPNFSIFMLKVFMSLFTGVITGMWIWSHKTMNTWRAFYYKVSGKRPP 494
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Match: EDO40119 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S829]) HSP 1 Score: 179.489 bits (454), Expect = 1.502e-48 Identity = 147/530 (27.74%), Postives = 250/530 (47.17%), Query Frame = 3 Query: 72 FINNIRAVNDPYNQPN--CEKIKVPACQG--LLYQMTIFPNHMLHSTQDEAALEINEYVPLMRI-KCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMK-RFQYPERPIIFLSACYLVVGLTYVAGFFLN--DKVACAGPFTNKDSTGKTPKIVVQGTKFES--CIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWA-HESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKT--GGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 F I + + Y+Q + CE +K C G L Y T S+QD+ + ++ L + KC LQ FLC +Y P C LP CR C +K C + + Y +WP+ + CD PE N N T K+ N S +C L + +Y + S I+ CGI C F+E + R +VA + + TLFTV+TFL+ K + +YP + F++AC+ V + ++ F + KV C +D T + + + T+ +S C++ F+L+Y+FS+A W+V+L +W + K + ++ + YFH +W++PA T +L + +VD + ++G+CF G +PS GFL+APL + L+IG FL G ++F++R + K+++ I R+G F+ + + AC+ +E N +W + + +C I +H+ + N + + + GI W W+ T +WK + R+ Sbjct: 8 FCGIITSYSSAYSQGSYKCEPLKEQTCLGEKLDYHYTTTELVTDSSSQDQVKKNLEKWEGLKFLPKCWEVLQPFLCQIYKPKCKNGSVELP-CREQCFATRKPCSVV--ESYRRWPEFLRCDKLPEGNC----NGTLKKLHLNES-ACKAPL-VETAY----KPSWYEGIEGCGIQCMNPIFSEEEHTRIHR-FVAAFGTLTTVCTLFTVVTFLVGWKSQNRYPSVILFFMNACFCVASVGFLIQFSSDARRKVVC-----RRDDTMR----LGEPTESDSFLCVLTFVLVYYFSLAGMTWFVMLAYSWCICFKTLGSTRDNFAGKTGYFHIISWSLPAVLTGCVLLVKQVDANSISGICFVGYKNPSMRAGFLLAPLGLDLVIGGMFLAKGLFTLFKLRKSNPNFLSNRASIKIKETIMRVGFFAFVAFAFVFITFACHVYEYYNQERWERSYRAFLMC-----------IANHE-VKGVSNTCSIKDRANLSVLELSLSSLFGAGIAMSGWTWTSNTFKTWKKLWHRV 502
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Match: fzd7b (frizzled class receptor 7b [Source:ZFIN;Acc:ZDB-GENE-990415-229]) HSP 1 Score: 492.656 bits (1267), Expect = 1.534e-166 Identity = 258/545 (47.34%), Postives = 352/545 (64.59%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENN---LCIRDNQTEKESA--------------PNV-------------SLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNR------YYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGD 1646 C+ I +P C + Y TI PN + H+ Q++A LE++++ PL++++C L+ FLCS+Y PVCT++++A+PPCRSLC + ++ CE ++ KF F+WP+ + C+ +P N +C+ N +E S PN SCP L++P ++ ++DCG PC YF E + KF R+WV +WS +C STLFTVLT+L+DM+RF+YPERPIIFLS CY +V + Y AGFFL DKV C F G+ + V QGTK E C ILFM+LYFF MAS+IWWV+L++TW+L+A W HE+I NSQYFH AAWA+PA KTI ILA+ +VDGD LTGVCF G+ + LRGF++APL +YL IGT FL+AGFVS+F IRTI+K G+KT+KLEKL+ RIG+FSVLY VPA +VIACYF+E W + W++ C+ + C +H+ P+ P+F +FMIKYLM++IVGITSG W+WSGKTL SW+ F+ RL G N G+ Sbjct: 30 CQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSTELKFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLHCEAFPVNGGSEICVGQNTSEPGSPSSSSPHVPELVTVPPNRFPNPPQPPHNSYHQFSCPLQLEVPSYLGYRFM-----GVKDCGAPCEPTKPSGIMYFREDEV-KFGRLWVGIWSILCCVSTLFTVLTYLVDMRRFRYPERPIIFLSGCYFMVAVAYAAGFFLEDKVVCVDKFK-----GEGFRTVAQGTKKEGCTILFMVLYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILAMGQVDGDVLTGVCFVGIFNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERTWHM-QTCK--RFAVPC-PVHNFAPMT-----------PDFTVFMIKYLMTMIVGITSGFWVWSGKTLQSWRRFYKRL-GNGNHGE 547
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Match: fzd2 (frizzled class receptor 2 [Source:ZFIN;Acc:ZDB-GENE-990415-224]) HSP 1 Score: 475.322 bits (1222), Expect = 9.387e-160 Identity = 250/534 (46.82%), Postives = 345/534 (64.61%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRDNQTE-------------KESAPNVS-----LSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCN------RYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLN 1637 C++I +P C + Y TI PN M + Q++A LE++++ PL++++C L+ FLCS+Y PVCT+++K +PPCR +C + ++ CE ++ KF F+WP+ + C+ +P +C+ N++ P VS +CP L++P ++ + DCG PC +F++ + FAR+WV +WS +C ST FTV T+LIDM+RF+YPERPIIFLS CY +V + ++AG+FL DKVAC F N D K VVQGTK E C ILFM+LYFFSMAS+IWWV+L++TW+LAA W HE+I NSQYFH AAWA+PA KTI ILA+ +++GD L+GVCF LS+ LRGF++APL IYL IGT FL+AGFVS+F IRTI+K G+KT+KLE+L+ RIG+FSVLY VPA +VIAC+F+E W + W + CRS + +P P+F ++MIKYLM+LIVGITSG WIWSGKTL SW+ F++RL N Sbjct: 35 CQQISIPLCTDIAYNQTIMPNLMGNHNQEDAGLEVHQFFPLVKVQCSPELKFFLCSMYAPVCTVLEKPIPPCRPICEKARQGCEALMNKFGFQWPEKLRCENFPLLGDHGQICVGQNESSSPTAPPPLPPAPGTRELPRVSTHERPFTCPSVLRVPPYLNYHFLEEK-----DCGAPCESPRNGGNMFFSDKEIH-FARMWVLIWSVLCCTSTFFTVTTYLIDMQRFRYPERPIIFLSGCYTMVSIAFIAGYFLGDKVACNDSF-NPDGY----KTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTISILAMGQIEGDVLSGVCFVSLSNLDPLRGFVLAPLFIYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEQLMVRIGVFSVLYTVPATIVIACFFYEQAFRPHWERSWVSRN-CRSLAIPCPAQS----RP----------HMTPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTSGKN 542
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Match: ENSORLT00000002667.2 (pep primary_assembly:ASM223467v1:17:316235:318512:1 gene:ENSORLG00000002147.2 transcript:ENSORLT00000002667.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 422.935 bits (1086), Expect = 4.321e-139 Identity = 235/552 (42.57%), Postives = 326/552 (59.06%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE----NNLCIRDNQTEKESAPNVSLSCPKSLQ----------------------------------IPVSYDF-----KIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVAC----AGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 C++I VP C+G+ Y T PN H TQDEA LE++++ PL+ IKC L+ FLCS+Y P+C KK LPPCR +C + K C P+++++ F WP M CDL PE ++LC+ + +P ++ + L+ +PVS + ++R Q I +C +PC YF + R F W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACY+ V + Y+ +++VAC + + ++TG P + C I+F+L+YFF MAS+IWWV+L++TW+LAA W +E+IG SQ+FH AAW IP+ K+I +LALS VDGD + GVC+ G + +LRGF++APL IYL+IGT FL+AGFVS+F IR++IK GG+KTDKLE+LI RIG+F+VLY VPA V++ACYF+E N Q W + C A + Q+P + +FM+KY M L+VGITSG WIWSGKTL +W+ F R C Sbjct: 23 QCQEISVPLCKGIGYNYTHMPNKFHHDTQDEAGLEVHQFWPLVEIKCSPDLRFFLCSMYTPICLEDYKKPLPPCRGVCERAKAGCAPLMRQYGFPWPDRMRCDLLPEQGNHDSLCMDYSSQTTTVSPALAKPTNRPLKPYNKRKGPYGRTFPGKHKPAGSPCEAACSCRAPMVPVSSEGHPLHNRVRTGQ---IVNCAVPCYNPYFTQEE-RTFTSFWIGLWSILCFISTFTTVATFLIDMERFKYPERPIIFLSACYMFVSVGYIVRLVAGHEEVACNMWNGAGYIHYETTG--PAL---------CTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIGSYSQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGVCYVGNQNLDSLRGFVLAPLVIYLVIGTMFLLAGFVSLFRIRSVIKQGGTKTDKLERLIIRIGVFTVLYTVPATVIVACYFYEQHN----RQAWEITHNCTCATEPSK--------------------QRPNYAVFMLKYFMCLLVGITSGAWIWSGKTLDTWRTFCRRCC 535
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Match: fzd8a (frizzled class receptor 8a [Source:ZFIN;Acc:ZDB-GENE-000328-3]) HSP 1 Score: 422.165 bits (1084), Expect = 8.237e-139 Identity = 236/544 (43.38%), Postives = 322/544 (59.19%), Query Frame = 3 Query: 117 NCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP----ENNLCIRDNQTEKESAP-------NVSLSCPKS------------------------LQIPVSYDFKIRLSQNSV----IQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 C+ I VP C+G+ Y T PN H TQDEA LE++++ PL+ I+C L+ FLCS+Y P+C KK LPPCRS+C + + C P+++++ F WP M CDL P + LC+ N+ + +A N PKS L+ V+ + N V + +C +PC+ YF + R F W+ LWS +C ST TV TFLIDM+RF+YPERPIIFLSACY+ V + Y+ ++KVAC N+D I + T C I+F+L+YFF MAS+IWWV+L++TW+LAA W +E+I +Q+FH AAW IP+ K+I +LALS VDGD + G+C+ G + LRGF++APL IYL IGT FL+AGFVS+F IR++IK GG+KTDKLEKL+ RIGIF+VLY VPA V++ACYF+E N Q W + C S + E + P++ +FM+KY M L+VGITSG+WIWSGKTL SW+ F +R C Sbjct: 20 TCQGIAVPLCKGIGYNYTYMPNQFNHDTQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFPWPDRMRCDLLPVQGNPDTLCMDYNRNDSTTASPVLSKPTNHPGRSPKSKPGRAGAPGKYKPPAAPCEPGCRCLEPMVAVTTERHPLYNRVKTGQVTNCAMPCHNPYFTH-DERAFTAFWIGLWSVLCFVSTFATVATFLIDMERFKYPERPIIFLSACYMFVSVGYIVRLIAGHEKVAC-----NRDF--DVEHIHYETTGPALCTIVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIASYAQHFHLAAWLIPSMKSIAVLALSSVDGDSVAGICYVGNQNLDNLRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTVLYTVPATVIVACYFYEQHN----RQDWEMTHNCSSCLMERERAR-----------------SGPDYAVFMLKYFMCLLVGITSGVWIWSGKTLDSWRTFCTRCC 534
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Match: ENSORLT00000013002.2 (pep primary_assembly:ASM223467v1:21:5638676:5644296:-1 gene:ENSORLG00000010376.2 transcript:ENSORLT00000013002.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 420.624 bits (1080), Expect = 2.279e-138 Identity = 235/529 (44.42%), Postives = 318/529 (60.11%), Query Frame = 3 Query: 120 CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVC-TIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPE---NNLCIRDNQTEKE-SAPNVSLSCPKSLQIPVS---YDFKIRLS-----------------QNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECK-KIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLC 1625 CE I VP C+G+ Y +T PN H TQ+E LE++++ PL+RI+C L FLCS+Y P+C +K LPPCRS+C + K+ C P++ ++ F+WP+ MSC+ P+ LC+ N +E SAP S PK P S D + R Q + +C +PC+ YF+ + R F WV LWS +C STL TV TFLIDM+RF+YPERPIIFL+ACYL V L Y+ +++VAC T++ I+ T C ++F+L+YFF MAS+IWWVVL+ TW+LAA W E+I SQYFH AAW IP+ K+I +LALS VDGDP+ G+C+ G LRGF++APL +YL GT FL+AGFVS+F IR+IIK GG+KTDKLE+L+ RIG+F+VLY VPA +V+AC +E W E C + + I + P++ +FM+KY M L+VGITSG+WIWSGKTL SW+ F +R C Sbjct: 24 CEPITVPMCKGIGYNLTYMPNKFNHDTQEEVGLEVHQFWPLVRIRCSPDLLFFLCSMYTPICLPDYRKPLPPCRSVCERAKRGCSPLMSQYGFEWPERMSCEGLPQLGDETLCMDQNSSEATTSAPPFPKSTPKVRTRPPSPSQCDRECRCRDPLIPIKRESHALFGRVQTGPLPNCALPCHLPYFSA-DERAFTSFWVGLWSVLCFISTLTTVATFLIDMERFKYPERPIIFLAACYLFVSLGYIIRLVAGHERVACGAGGTSQL------HILYDATGPALCTLVFLLVYFFGMASSIWWVVLSFTWFLAAGMKWGSEAIAGYSQYFHLAAWLIPSVKSILVLALSSVDGDPVAGICYVGNQSLENLRGFVLAPLVVYLFTGTLFLLAGFVSLFRIRSIIKQGGTKTDKLERLMIRIGLFTVLYTVPATIVVACLVYEQHYRPSW-------------ERALACSCPLERQRSI----------RGPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRSFVARCC 522
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Match: SMESG000040115.1 (SMESG000040115.1) HSP 1 Score: 1159.05 bits (2997), Expect = 0.000e+0 Identity = 592/592 (100.00%), Postives = 592/592 (100.00%), Query Frame = 3 Query: 165 MTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLXXXXXXXXXXXXXXXXXXKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 1940 MTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM Sbjct: 1 MTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 592
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Match: SMESG000040115.1 (SMESG000040115.1) HSP 1 Score: 1143.26 bits (2956), Expect = 0.000e+0 Identity = 585/585 (100.00%), Postives = 585/585 (100.00%), Query Frame = 3 Query: 186 MLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLXXXXXXXXXXXXXXXXXXKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 1940 MLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM Sbjct: 1 MLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGGSKTDKLEKLITRIGIFSVLYVVPAVVVIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRLCGRLNPGDPWTRSDWLEKNNGYYQRHFVGPTANKMIIQGCDDKQAIPLQYQFPQQTQQTIGTQELQKPLLSNVPESILNAQAQNGNLLPPSQQIGDSKTQKIGFMM 585
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Match: SMESG000005043.1 (SMESG000005043.1) HSP 1 Score: 370.163 bits (949), Expect = 3.295e-118 Identity = 217/531 (40.87%), Postives = 304/531 (57.25%), Query Frame = 3 Query: 87 RAVNDPYNQPN-----CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIM-KKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIRDNQTEKESAPNVSLSCPKSLQIPVSYDFKIRLSQNSVIQ----DCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDK-VACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGG-SKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL----CGR 1631 RA D NQ N C I +P C+ + Y +T PN H TQ+EA L ++++ PL+ I C +L+LFLCSLY P+C K + CRS+C + C P++ + FKWP+SM CD EN C++ + P S C + P YD K + NSVI +C C+ F + + F W+ LW+ +C S+ TVLTFL+D RF+YPERPI+FLS CY++V + Y+ + + +AC G +TG C I+F+L+YFF MA+++WWV+LTITW+L+A W E+I + S+ FHF AW + K+I L L +DGDP+ G+C+ G ++ L+ FLI PL +YLLIG+ FL++GF+++ IR I+ G SKTDKLEKL+ RIGIF +LY VPA VVI C+ +E N W E + C + ++ I N FS KPE+ +FM+KY M L+VGITSG WIW+ KTL SW F RL CG+ Sbjct: 43 RASADRSNQENFRPNKCVPIAIPMCKNIGYNLTYMPNEFHHETQEEAGLVVHQFYPLVEIACSDNLRLFLCSLYAPICLPNWPKPIQACRSVCESARDGCAPVMNTYGFKWPKSMDCDKLTENQACLKKDTKNVTKPP--SKGCECKCRSPYIYDNKPQF--NSVITGGVANCFQSCHSANFVSID-KSFVTFWLGLWAVLCCLSSTATVLTFLLDRSRFKYPERPIVFLSGCYMMVSIGYIIRVAVGHELIACDGDKLRYGTTGPA-----------RCSIVFLLIYFFGMAASVWWVILTITWFLSAGLKWGSEAISKYSEIFHFLAWFLSGVKSILALTLVAIDGDPVGGICYIGNTNSLNLKLFLIVPLTVYLLIGSCFLLSGFIALISIRKTIRAKGESKTDKLEKLMMRIGIFGLLYSVPAAVVIGCHLYEVKNREFW-------------EKSNNC---YCNRNIKSQEN---FS-KPEYSVFMLKYFMCLVVGITSGFWIWTSKTLDSWHNAFRRLSQSICGQ 537
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Match: SMESG000035834.1 (SMESG000035834.1) HSP 1 Score: 368.622 bits (945), Expect = 3.664e-116 Identity = 215/562 (38.26%), Postives = 312/562 (55.52%), Query Frame = 3 Query: 84 IRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTIMK-KALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYP-----ENNLCIRDN-QTEKESAPNVSLSCPK------SLQIP-------VSYDFKIRLSQNSVIQ---------------------------DCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFLNDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIK--TGGSKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 +++ N ++ CE IK+P C+ + Y MT+ PN H QDEA E +++ PL++IKC LQ FLCS+Y P+C K+LPPCRS+C ++KK C+P+L+K+ FKWP+ M+CD +P E LC+ N T + +V PK S Q+ VSY + + Q +C C +F+ + +KF W+ LW+ +C+ ST V TF ID R++YPERPIIF+S CY +V L ++ + + KD + + + G+ C I+F+L+Y+F MA+++WWV+LTITW+LAA W E+I + SQ +HF AW +P K+I L +S VDGDP++G+C+ G + L F+++PL +YL IGT LI+GF S+F IR+IIK TGG KT+KLEKL+ RIG+FSVLY PA V++AC +E N +W Q +C + H+ P +P + +FM KY M + VG+TSG WIWS KT+LSWK RL Sbjct: 31 LKSDNTNRDKGKCEIIKIPMCKDIHYNMTMMPNMFNHENQDEAGFEAHQFYPLVQIKCSEDLQFFLCSIYTPICLKQYVKSLPPCRSVCERVKKGCDPLLQKYTFKWPEKMNCDQFPVYNNPEKILCMEKNLSTASTTLASVVTLAPKEQNDANSRQVAEQNLLNEVSYQLTRQYNSRVFCQCSCRKPLIDIAEINKAHFNRVSTLGMFNCAQGCKSPFFSSESDQKFIGFWLGLWTIICLLSTFSIVATFSIDPGRYRYPERPIIFMSICYFMVSLGFLIRIVMGHEDLACDSIKAKDGSSLS-LLRYGGSGPAHCTIVFLLIYYFGMAASLWWVLLTITWFLAAGLKWGSEAISKYSQIYHFLAWFLPGIKSIVALTMSAVDGDPVSGICYVGNTSDFNLILFVLSPLLVYLTIGTLVLISGFASLFRIRSIIKLQTGG-KTEKLEKLMIRIGVFSVLYTAPAAVIVACIIYELQNRAEWYQ-----------NLSCDCFDSNRHQLNLP---------RPSYSVFMFKYFMFMGVGMTSGFWIWSKKTILSWKMVCYRL 570
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Match: SMESG000031852.1 (SMESG000031852.1) HSP 1 Score: 360.918 bits (925), Expect = 4.179e-115 Identity = 205/527 (38.90%), Postives = 305/527 (57.87%), Query Frame = 3 Query: 90 AVNDPYNQPN-CEKIKVPACQGLLYQMTIFPNHMLHSTQDEAALEINEYVPLMRIKCHGSLQLFLCSLYFPVCTI-MKKALPPCRSLCLQIKKECEPILKKFYFKWPQSMSCDLYPENNLCIR-DNQTEKESAPNV---------SLSCPKSLQIPVSYDFKIRLSQ--NSVIQDCGIPCNRYYFNEPNLRKFARVWVALWSFMCVGSTLFTVLTFLIDMKRFQYPERPIIFLSACYLVVGLTYVAGFFL-NDKVACAGPFTNKDSTGKTPKIVVQGTKFESCIILFMLLYFFSMASAIWWVVLTITWYLAAKCHWAHESIGRNSQYFHFAAWAIPAGKTIGILALSKVDGDPLTGVCFTGLSDPSTLRGFLIAPLCIYLLIGTGFLIAGFVSMFEIRTIIKTGG-SKTDKLEKLITRIGIFSXXXXXXXXXXIACYFHESMNLYKWMQRWYLIDICRSAEYKDECKKIHDHKPINPGGNALIFSQKPEFELFMIKYLMSLIVGITSGIWIWSGKTLLSWKYFFSRL 1622 +++ P +P+ C I++ C+G+ Y +T PN + H++ +EA LEI ++ L+ I C L+LFLCS+Y P+C +P CRSLC+ ++ C ++ ++ FKWP+ M+C+ PE+N C+R DN+T N S C + P+ D + ++ I +C + C YF E + + F+ W+ +W+ +C+ ST T+LTF ID RFQYPERPIIFLS CYL++ + Y+ L ++ VAC S+G P C I+F+ +YFF MAS+IWWVVLT TW+LAA W E+I + +HF AW IP ++I IL +S VDGDP++G+C+ G + L F+I PL +YLL+GTGFL+AGF+++ +IR IK G SKTDKLEKL+ RI IF ++Y VP + V+ C +E + W Q + CR+ +Y +PE+ +FM+KY M+L+VG T+G WIW+ KTL SW F +L Sbjct: 24 SISKPDLRPSTCIPIEISMCKGIGYNLTYIPNDLNHASLEEAGLEIQQFNALVEINCSEDLRLFLCSMYAPICLPNWPNRIPACRSLCISAREGCTRVMNQYGFKWPEGMNCEKLPEDNACLRKDNKTRSNKTANFVSERPYLLKSKKCHCHCRSPLIIDSRDHFNKVVTGNISNCLMNCRSPYFGEFD-KSFSTFWLGIWACVCIISTSVTILTFCIDKSRFQYPERPIIFLSICYLLMSVGYLIRVALGHEAVACKSDAIRYGSSGAVP-----------CSIVFLFIYFFGMASSIWWVVLTATWFLAAGLKWGSEAILMYADIYHFFAWFIPGIQSIIILTMSSVDGDPVSGICYVGNLNKYNLLFFVIIPLIVYLLVGTGFLLAGFLALMKIRKTIKEKGESKTDKLEKLMIRISIFGIVYSVPTMTVVFCSIYEFIFRDLWEQSYTC--PCRTKKY------------------------QPEYSVFMLKYFMNLVVGTTAGFWIWTPKTLDSWSKVFCKL 512 The following BLAST results are available for this feature:
BLAST of Fzd-1/2/7 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Fzd-1/2/7 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Fzd-1/2/7 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Fzd-1/2/7 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Fzd-1/2/7 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025215 ID=SMED30025215|Name=Fzd-1/2/7|organism=Schmidtea mediterranea sexual|type=transcript|length=2307bpback to top protein sequence of SMED30025215-orf-1 >SMED30025215-orf-1 ID=SMED30025215-orf-1|Name=SMED30025215-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=638bp MLIKYFLIVSFVFLFINNIRAVNDPYNQPNCEKIKVPACQGLLYQMTIFPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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