Ankyrin repeat and EF-hand domain-containing protein 1
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30025084 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Match: ANKEF1 (ankyrin repeat and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15803]) HSP 1 Score: 541.576 bits (1394), Expect = 3.298e-180 Identity = 320/776 (41.24%), Postives = 450/776 (57.99%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLG----KNNEP-WALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALP-PVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALK----RANNLLS--YSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI KVLQC KD QI+KL G LINY EP NG + L +A+ ND+D + FLLDLGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN + +GK + ACED + +++CL L+ GA+PN I +TG+T LM A G I L+ G + N D A H+AAK G F L L A+ + N P+HYAA G A CCK++ QRGC+ K KN + + R +AK+ G K KE+ + ER KL KN P WAL L+DW+VE + E +LD G ++K +FV +L + + E I +K + G + +F G +Y+NK +++ ++ KKK+K G KGK K +P+ ICV+PE R DGGPP I + TD +RF+ ++PP + I+DD WYI D ++ F N+N K GDL S+K A + G VD +D +YKT LM+A GN+D+ L+ GA+VNA DNF WTPLH A H+G DIVELL+ +GA++DA ++N +TPL RAIES R + V++LL GAK Q+EN KG + +D+A +AD R+I++IK K+D LP P +++K +G + ++G + + P S + K N+L++ Y+ K DI+F PR + L++ R RR+RF E+DF D+F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLD-RGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKG-KTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKV----DITFIPRRIWSPEATTAELIRKRELRRERFTHEVDF-DDFMMPFQKNITEKARA 769
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Match: ANKEF1 (ankyrin repeat and EF-hand domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15803]) HSP 1 Score: 541.576 bits (1394), Expect = 3.298e-180 Identity = 320/776 (41.24%), Postives = 450/776 (57.99%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLG----KNNEP-WALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALP-PVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALK----RANNLLS--YSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI KVLQC KD QI+KL G LINY EP NG + L +A+ ND+D + FLLDLGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN + +GK + ACED + +++CL L+ GA+PN I +TG+T LM A G I L+ G + N D A H+AAK G F L L A+ + N P+HYAA G A CCK++ QRGC+ K KN + + R +AK+ G K KE+ + ER KL KN P WAL L+DW+VE + E +LD G ++K +FV +L + + E I +K + G + +F G +Y+NK +++ ++ KKK+K G KGK K +P+ ICV+PE R DGGPP I + TD +RF+ ++PP + I+DD WYI D ++ F N+N K GDL S+K A + G VD +D +YKT LM+A GN+D+ L+ GA+VNA DNF WTPLH A H+G DIVELL+ +GA++DA ++N +TPL RAIES R + V++LL GAK Q+EN KG + +D+A +AD R+I++IK K+D LP P +++K +G + ++G + + P S + K N+L++ Y+ K DI+F PR + L++ R RR+RF E+DF D+F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLD-RGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKG-KTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKV----DITFIPRRIWSPEATTAELIRKRELRRERFTHEVDF-DDFMMPFQKNITEKARA 769
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Match: ANK3 (ankyrin 3 [Source:HGNC Symbol;Acc:HGNC:494]) HSP 1 Score: 110.538 bits (275), Expect = 8.333e-24 Identity = 143/616 (23.21%), Postives = 240/616 (38.96%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELK--LLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMSAF-----EXXXXXXXXXXXXXXXXXXIPIEICVMPESH--IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPD----RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
N T L +A+ + + +K LLD GA D +G + + A+ GH E L A + NG + L+ H C++ L++NV +++V+ D T L A G + ++ +LL A+PN +K L +G T +H A K K + L GA ++ PIH AA GH + L G +P N GE A +A A+ EV++ + V++ ++ + K L S + K + V L++ A N P ++G D A FL T KK L++ + + +K + P+ + ++ + +D G K Y T L+ + +N +I Y D + + +++ AA+ G +D + L L + V+ ++ T L AA +++ L+N GA V+A+ +TPLH H G I IV L+ + A V+AK NG TPL +A + +++ LL+ A G T L +A V++ +K
Sbjct: 261 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQ--GDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG--HYKVAKVLLDKKANPN-----------------------AKAL-----------NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMA----ARSGQAEVVR---------------------YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKN--QMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLK 810 HSP 2 Score: 81.2629 bits (199), Expect = 8.171e-15 Identity = 49/133 (36.84%), Postives = 70/133 (52.63%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
AA+ D + L L+ D + T L AAHYGN+++ L+N A V+ TPLH A+ G ++V+LL++ GA +DAK +G TPL S VVE LL + A I + GL+PL +A
Sbjct: 203 AARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 335 HSP 3 Score: 80.4925 bits (197), Expect = 1.281e-14 Identity = 53/160 (33.12%), Postives = 77/160 (48.12%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA G ++ + + G +T + +TAL AA G ++ +L+ GA V AK TPLH +A G DIV+ L+ GA +A +G TPL + +V FLL GA + + KG TPL +A + V N++ K A P K G
Sbjct: 434 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK-SASPDAAGKSG 592 HSP 4 Score: 78.5666 bits (192), Expect = 4.497e-14 Identity = 45/145 (31.03%), Postives = 81/145 (55.86%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ G L+ +K G ++ ++ AL A+ G++++ L+ A+V+A T LH A+ +G ++V++L+ NGA V+A++ NG TPL+ A + + VV+FLL GA + G TPL +A +V++++
Sbjct: 42 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 186 HSP 5 Score: 77.7962 bits (190), Expect = 8.496e-14 Identity = 52/162 (32.10%), Postives = 77/162 (47.53%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
+ F ++ AAK+G L+ L L+K D + T L AAHY N + + L++ GA +A +TPLH AA +DI L+ GA +A G + A + ++V LL + A + + N GLTPL LA V ++ A VDA
Sbjct: 558 KGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA 719 HSP 6 Score: 74.3294 bits (181), Expect = 9.053e-13 Identity = 46/151 (30.46%), Postives = 76/151 (50.33%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
F ++ AA +G+++ L L + VD R T L A+ GN +M L++ GA ++AK TPLH A SG +VE+L++ A + +K NG +PL A + N V+ LL+ + + LT L +A + +V ++
Sbjct: 230 FTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 380 HSP 7 Score: 72.7886 bits (177), Expect = 2.967e-12 Identity = 56/170 (32.94%), Postives = 80/170 (47.06%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLI--NYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
F + A + G + L L+ DT+ + AL AA + L+ + ADV +K F TPLH AAH G I++ LL+N A VD A N TPL A + N+V+ LL +GAKI + GLTPL +V+ ++ +D P+ K G
Sbjct: 168 FTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGF--TPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML---LDRAAPILSKTKNG 328 HSP 8 Score: 72.4034 bits (176), Expect = 3.667e-12 Identity = 65/234 (27.78%), Postives = 105/234 (44.87%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGH--VASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA 917
++ LV +G + + D+ +T L I+ D ++ LL GA P+ G + + ++A+ GH VA+F L GA L + G L+ V+ E L+ + + K G T L A +N+++ L+LL GA P+ K G TPL A I + L+ G D N R G +VH AA+ G+ + L A ++ + + P+H AA
Sbjct: 476 VRYLVQDGAQ--VEAKAKDD-QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF--LLDHGASLSITTKKGFTPLH--VAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAH--YDNQKVALLLLDQGASPHAAAK-NGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAA 699 HSP 9 Score: 71.633 bits (174), Expect = 6.809e-12 Identity = 53/162 (32.72%), Postives = 77/162 (47.53%), Query Frame = 3
Query: 1623 AKHGD-LDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---------KAKVDALP 2078
A GD L+ ++L L+ VD Y TAL AAH G+ + L++ A+ NAK +TPLH A I ++ELL+ +GA + A +G TP+ A N+V L+ GA N +G T L +A + V+ + KAK D P
Sbjct: 335 ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 496 HSP 10 Score: 66.6254 bits (161), Expect = 2.433e-10 Identity = 67/265 (25.28%), Postives = 105/265 (39.62%), Query Frame = 3
Query: 231 LVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
L+D+G I + G T L +A L+ LL A PD G + + +AA Y + L GA NG L+ ++ + + T L Y D N V++ G + A ++G + ++ +LL A+ N+ K +G TPL A ++ + G + + G T +H GN K + L A+ + P+H AA GH L Q +P NG A IA+ G
Sbjct: 545 LLDHGASLSITTKK---GFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEG--HVDMVSLLLGRNANVNLSNK-SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLG 801 HSP 11 Score: 63.1586 bits (152), Expect = 2.417e-9 Identity = 76/251 (30.28%), Postives = 108/251 (43.03%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYN-EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNV---SKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQN--NPIHYAAAG-HASCCKFLGQ 953
+K LV NG N N + NG T L +A EN L+ +KFLLD GA + +G + + +A Q GH L + ND GK V + R + AL D NN SK G T L A G N + +LL A + + TPL A G+ ++ L G + R G T +H A+SG+ + + L A + T+N +P+H A G H +C + L Q
Sbjct: 117 VKVLVTNGA----NVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGK-VRLPALHIAARKDDTKAAALLLQND-NNADVESKSGFTPLHIAAHYGNIN--VATLLLNRAAAVDFTAR-NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAA--PILSKTKNGLSPLHMATQGDHLNCVQLLLQ 349 HSP 12 Score: 62.3882 bits (150), Expect = 4.263e-9 Identity = 46/181 (25.41%), Postives = 82/181 (45.30%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLK---------------------KGAKIQMEN--------SKGLTPLDLAYNWADSRVINIIKAKVDAL 2075
A+K G ++ + L++ VD + TAL A+ G ++ L+ GA+VNA+ +TPL+ AA +++V+ L++NGA +G TPL A++ VV LL+ K A + ++N G TPL +A ++ + V ++ + A+
Sbjct: 75 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAV 255 HSP 13 Score: 55.4546 bits (132), Expect = 5.885e-7 Identity = 37/133 (27.82%), Postives = 61/133 (45.86%), Query Frame = 3
Query: 1671 YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
Y +R + + AA G+L+ + I G D+N + LH A+ G +++V L+ A VDA G T L A + + VV+ L+ GA + ++ G TPL Y A + ++K +D
Sbjct: 26 YSRSSRKSDANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPL---YMAAQENHLEVVKFLLD 155
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Match: TNKS (tankyrase [Source:HGNC Symbol;Acc:HGNC:11941]) HSP 1 Score: 108.612 bits (270), Expect = 2.573e-23 Identity = 155/652 (23.77%), Postives = 257/652 (39.42%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKT-----------VLFHACEDGKE-------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMK------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTF---VNMNDAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDL 2015
+R++L+ D ++K+LVD N N D + L A D ++ LL +GA+ D G + A +GH L GAD D N + + + C+ L++ D N + DGK+ VL C+ + NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N +G+ A +A ++ + +++ R L K + AL + ++ E + L +K+ +LL+R A +NE+ + + P + D + L K+ K+ + + ++ C + S+ G P + L F++ + ++ S P RT + +A+K GDL+++K L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL
Sbjct: 183 LRELLEACRNGDVSRVKRLVDAA-----NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD-NWNYTPLHEAAIKGKIDVCI-VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGQCKSSEHVKFYRSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAARE-ADLAKVKKTLALEIINFKQPQSHETALHCAVASLHP----KRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDTLGQTALHRAALAGH--------LQTCRLLLSY------GSDPSI--------ISLQGFTAAQMGNEAVQQILSE--STPIRTSDVDYRLLEASKAGDLETVK-QLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789 HSP 2 Score: 86.2705 bits (212), Expect = 1.968e-16 Identity = 67/169 (39.64%), Postives = 87/169 (51.48%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSI-KLALKKGYKV-DTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
I D R + DAAK G L + KL + DT+ R T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G TPLDLA AD +I +DA+PP
Sbjct: 797 IQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR-NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA--TAD----DIRALLIDAMPP 958 HSP 3 Score: 68.1662 bits (165), Expect = 6.677e-11 Identity = 40/105 (38.10%), Postives = 56/105 (53.33%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T L AA Y + + L+ +GADV+AKD PLH+A G ++ ELL+ +GA V+A L TPL A +R V LL GA + N G + +D+A
Sbjct: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475 HSP 4 Score: 65.855 bits (159), Expect = 3.212e-10 Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ +D + + L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G + LDLA
Sbjct: 188 EACRNGDVSRVK-RLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322 HSP 5 Score: 59.6918 bits (143), Expect = 2.911e-8 Identity = 48/166 (28.92%), Postives = 78/166 (46.99%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGA-----VVDAK-ALNGATPLFRAI--------ESSRF-------NVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA G D ++ L+ G V RD L +A +G+ ++ L+ GAD NA+DN+++TPLH AA G ID+ +L+ +GA D K AL+ A P +A+ E +F ++ L + + TPL LA + R++ ++
Sbjct: 223 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGQCKSSEHVKFYRSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLL 388 HSP 6 Score: 57.3806 bits (137), Expect = 1.615e-7 Identity = 97/441 (22.00%), Postives = 162/441 (36.73%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSE---NDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILL------------------KHGADPNIIQKATGK------------TPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAK-----------------DKGAKDCMKEVIKV-----ERSFGKLGKNNEPWALG-------LYDWTVENMTEIVEELK--LLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL 1313
+LQ E D ++KK + +IN+ +P + +T L A + + LL GA+ + + + + + +AA+ H E L K GA + D G+ L+ + H + L Y D + +S G F A + G NE + IL K G + Q + + TPL A S+ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + K D K C+ V K+ G+N+ P L + ++ +E+ ++ + K L+ L N+ + LLI+ +N + P + + G L
Sbjct: 493 LLQAAREADLAKVKKTL---ALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR--AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMG--NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922 HSP 7 Score: 56.225 bits (134), Expect = 3.615e-7 Identity = 68/292 (23.29%), Postives = 111/292 (38.01%), Query Frame = 3
Query: 183 KVLQCTYEKDYDQIKKLVDNGVEHLINYNEPD---NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEI--------------CLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
++L+ + D + +K+L + N N D T L A N + +++LL GA D G + A YGH E L + GA + + DL L+ + + E + L++ D ++DG T L E + +++ CL ++ P I + TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN G+
Sbjct: 653 RLLEASKAGDLETVKQLCSSQ-----NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 937 HSP 8 Score: 54.299 bits (129), Expect = 1.205e-6 Identity = 45/173 (26.01%), Postives = 77/173 (44.51%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDA--------------------KALNG--ATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
V +++A +G + +L ++ G V+ D + T L AA G ++C L+ +GAD K+ TPL G DI +LL + A++DA + G +TPL A + V E+LL+ GA + ++ GL PL A ++ + ++
Sbjct: 718 LVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-DLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Match: TNKS (tankyrase [Source:HGNC Symbol;Acc:HGNC:11941]) HSP 1 Score: 108.612 bits (270), Expect = 2.573e-23 Identity = 155/652 (23.77%), Postives = 257/652 (39.42%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKT-----------VLFHACEDGKE-------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMK------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTF---VNMNDAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDL 2015
+R++L+ D ++K+LVD N N D + L A D ++ LL +GA+ D G + A +GH L GAD D N + + + C+ L++ D N + DGK+ VL C+ + NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N +G+ A +A ++ + +++ R L K + AL + ++ E + L +K+ +LL+R A +NE+ + + P + D + L K+ K+ + + ++ C + S+ G P + L F++ + ++ S P RT + +A+K GDL+++K L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL
Sbjct: 183 LRELLEACRNGDVSRVKRLVDAA-----NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD-NWNYTPLHEAAIKGKIDVCI-VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGQCKSSEHVKFYRSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAARE-ADLAKVKKTLALEIINFKQPQSHETALHCAVASLHP----KRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDTLGQTALHRAALAGH--------LQTCRLLLSY------GSDPSI--------ISLQGFTAAQMGNEAVQQILSE--STPIRTSDVDYRLLEASKAGDLETVK-QLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789 HSP 2 Score: 86.2705 bits (212), Expect = 1.968e-16 Identity = 67/169 (39.64%), Postives = 87/169 (51.48%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSI-KLALKKGYKV-DTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
I D R + DAAK G L + KL + DT+ R T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G TPLDLA AD +I +DA+PP
Sbjct: 797 IQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR-NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA--TAD----DIRALLIDAMPP 958 HSP 3 Score: 68.1662 bits (165), Expect = 6.677e-11 Identity = 40/105 (38.10%), Postives = 56/105 (53.33%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T L AA Y + + L+ +GADV+AKD PLH+A G ++ ELL+ +GA V+A L TPL A +R V LL GA + N G + +D+A
Sbjct: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475 HSP 4 Score: 65.855 bits (159), Expect = 3.212e-10 Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ +D + + L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G + LDLA
Sbjct: 188 EACRNGDVSRVK-RLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322 HSP 5 Score: 59.6918 bits (143), Expect = 2.911e-8 Identity = 48/166 (28.92%), Postives = 78/166 (46.99%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGA-----VVDAK-ALNGATPLFRAI--------ESSRF-------NVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA G D ++ L+ G V RD L +A +G+ ++ L+ GAD NA+DN+++TPLH AA G ID+ +L+ +GA D K AL+ A P +A+ E +F ++ L + + TPL LA + R++ ++
Sbjct: 223 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGQCKSSEHVKFYRSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLL 388 HSP 6 Score: 57.3806 bits (137), Expect = 1.615e-7 Identity = 97/441 (22.00%), Postives = 162/441 (36.73%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSE---NDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILL------------------KHGADPNIIQKATGK------------TPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAK-----------------DKGAKDCMKEVIKV-----ERSFGKLGKNNEPWALG-------LYDWTVENMTEIVEELK--LLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL 1313
+LQ E D ++KK + +IN+ +P + +T L A + + LL GA+ + + + + + +AA+ H E L K GA + D G+ L+ + H + L Y D + +S G F A + G NE + IL K G + Q + + TPL A S+ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + K D K C+ V K+ G+N+ P L + ++ +E+ ++ + K L+ L N+ + LLI+ +N + P + + G L
Sbjct: 493 LLQAAREADLAKVKKTL---ALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR--AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMG--NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922 HSP 7 Score: 56.225 bits (134), Expect = 3.615e-7 Identity = 68/292 (23.29%), Postives = 111/292 (38.01%), Query Frame = 3
Query: 183 KVLQCTYEKDYDQIKKLVDNGVEHLINYNEPD---NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEI--------------CLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
++L+ + D + +K+L + N N D T L A N + +++LL GA D G + A YGH E L + GA + + DL L+ + + E + L++ D ++DG T L E + +++ CL ++ P I + TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN G+
Sbjct: 653 RLLEASKAGDLETVKQLCSSQ-----NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 937 HSP 8 Score: 54.299 bits (129), Expect = 1.205e-6 Identity = 45/173 (26.01%), Postives = 77/173 (44.51%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDA--------------------KALNG--ATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
V +++A +G + +L ++ G V+ D + T L AA G ++C L+ +GAD K+ TPL G DI +LL + A++DA + G +TPL A + V E+LL+ GA + ++ GL PL A ++ + ++
Sbjct: 718 LVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-DLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 112.079 bits (279), Expect = 9.617e-25 Identity = 154/639 (24.10%), Postives = 252/639 (39.44%), Query Frame = 3
Query: 291 CLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADL---------------KLNDLNGKNVLY-----------------YCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEI----CVMP---ESH------IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRT----FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
L IA ++D LL +PDV G + + IAA YGH + L + GA++ K N N+L +C + + H + ++ + ++ +K+G L A + ++ + LL H A + + TPL A G + L DPN+ +G T +H A K K + L + A + ++ P+H AA G + +L Q+G NP V+ GE +A D ++ +I R+ K+ L+ + T+IV L L NS + + L I K EE+ +L D N D T L KK L+L S + + P++I V P +H M ++ G K Y T L+ + +N EI + DP+ F ++ +A+ G + L ++ G V + TA+ A ++ + L N GA++N+K N +TPLH A H G +++V+ L+ NGA V K TPL +A + N V +LL+ GA + + G TPL +A V+ ++
Sbjct: 197 ALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSG-HDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG--DHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLI---RNGAKVDAQARELQTPLHIASRLGNTDIVI-LLLQAGANSNATTRDNYSPLHIAAKEG-QEEVAGILL---DHNADKT------LLTKKGFTPLHLASKY------GNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKKN--QMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 2 Score: 82.4185 bits (202), Expect = 1.417e-15 Identity = 48/145 (33.10%), Postives = 79/145 (54.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GDL+ + L+ G ++T + +L A+ G+ ++ LI A V+A T LH A+ +G IV +L+ NGA V+ +++NG TPL+ A + + VV++LLK GA + G TPL +A RV+ ++
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVL 184 HSP 3 Score: 79.7221 bits (195), Expect = 8.140e-15 Identity = 55/191 (28.80%), Postives = 89/191 (46.60%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
+ F ++ A+K+G+L+ ++L L++G VD + T L AAHY N +++ L+ + AD NAK +TPLH +A G +I LLI NG+ V AKA NG T + + V + L GA+I + + G TPL +A ++ +N++K V+
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQ---LNMVKFLVE 743 HSP 4 Score: 77.7962 bits (190), Expect = 3.562e-14 Identity = 53/154 (34.42%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
AA+ +D+ + L VD Y T L AAH G++ + L++ AD N++ +TPLH A I +VELL+ A ++A +G TPL A N+V +LL++GA +E +G TPL LA + V+ ++ AKVDA
Sbjct: 333 AAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486 HSP 5 Score: 70.4774 bits (171), Expect = 4.998e-12 Identity = 71/295 (24.07%), Postives = 122/295 (41.36%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNG 989
L+ D +++ +L+ G + IN + NG L +A+ E + ++ L+ A D +G +A+ IA+ G L + GA++ + +NG LY E H+E ++ L++ + ++DG T L A + G K++ +LL++ +P++ K +G TPL A G ++ L+ G + N RH + +H A K G L + GA D P+H AA +GH L +G K NG
Sbjct: 38 LRAARAGDLEKVLELLRAGTD--INTSNA-NGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ--ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSK-SGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNG 326 HSP 6 Score: 65.855 bits (159), Expect = 1.458e-10 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 168 ILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINY-----NEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+L+ R ++ T E + G +++ Y PD G+T L +A N D ++ L+ GA D E ++ + IA++ G+ L +AGA+ + + L+ ++ E +E L +N D ++K G T L A + G N E+ +LL+ G P I+ TPL A + + L+ G A ++G T +H AAK + L F A + P+H +A GH L + G + K +NG
Sbjct: 411 LLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYG--NLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNG 689 HSP 7 Score: 64.6994 bits (156), Expect = 3.579e-10 Identity = 60/259 (23.17%), Postives = 107/259 (41.31%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG T L IA +N + ++ LL A + G + + +AA G + L + GA+ + + G+ L+ + + + +R ++ +++ +T L A G N +I ++LL+ GA+ N + +PL A G + L D + G T +H A+K GN + + L G D+ Q P+H AA + L + G + K NG IA K + +++
Sbjct: 391 NGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQ--TDVVRVLIRNGAKVDAQARELQTPLHIASRLG--NTDIVILLLQAGANSNATTR-DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQ 644 HSP 8 Score: 62.003 bits (149), Expect = 2.490e-9 Identity = 52/192 (27.08%), Postives = 83/192 (43.23%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALR 854
NG T L IA +N ++ LL A P+ G + + ++AQ GH L + G+D+ NG ++ C E H + ++N+ + G T L AC G+ N + L+++GAD +A+ TPL A G + L+ G PN G+T + A + G + LR
Sbjct: 622 NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQ--EDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLN--MVKFLVENGADVGEKTRAS-YTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 9 Score: 53.1434 bits (126), Expect = 1.060e-6 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G + ++ +K+ +VD R TAL A+ G + L+ GA+VN + +TPL+ AA ++V+ L+ +GA +G TPL A++ VV LL+ +K
Sbjct: 73 ASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSK 190 HSP 10 Score: 52.7582 bits (125), Expect = 1.310e-6 Identity = 64/255 (25.10%), Postives = 105/255 (41.18%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA---DLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT--GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDC 1034
T L A + L+ GA G + + +AAQ HV + +L A D+ ++ L +V +C H + L + D N+ + +G T L AC+ K ++ +LLK+ A I+ T G TPL A G+ +I L+ G +P+ G+T +H AA++ + L GA+ D P+H A+ G+ L Q G N + IA +G ++
Sbjct: 295 TPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHC-----GHVRVAKLLLDRSADPNSRALNGFTPLHIACK--KNRIKVVELLLKYRA---AIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEV 539
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 112.079 bits (279), Expect = 9.617e-25 Identity = 154/639 (24.10%), Postives = 252/639 (39.44%), Query Frame = 3
Query: 291 CLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADL---------------KLNDLNGKNVLY-----------------YCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEI----CVMP---ESH------IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRT----FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
L IA ++D LL +PDV G + + IAA YGH + L + GA++ K N N+L +C + + H + ++ + ++ +K+G L A + ++ + LL H A + + TPL A G + L DPN+ +G T +H A K K + L + A + ++ P+H AA G + +L Q+G NP V+ GE +A D ++ +I R+ K+ L+ + T+IV L L NS + + L I K EE+ +L D N D T L KK L+L S + + P++I V P +H M ++ G K Y T L+ + +N EI + DP+ F ++ +A+ G + L ++ G V + TA+ A ++ + L N GA++N+K N +TPLH A H G +++V+ L+ NGA V K TPL +A + N V +LL+ GA + + G TPL +A V+ ++
Sbjct: 197 ALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSG-HDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG--DHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLI---RNGAKVDAQARELQTPLHIASRLGNTDIVI-LLLQAGANSNATTRDNYSPLHIAAKEG-QEEVAGILL---DHNADKT------LLTKKGFTPLHLASKY------GNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKKN--QMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 2 Score: 82.4185 bits (202), Expect = 1.417e-15 Identity = 48/145 (33.10%), Postives = 79/145 (54.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GDL+ + L+ G ++T + +L A+ G+ ++ LI A V+A T LH A+ +G IV +L+ NGA V+ +++NG TPL+ A + + VV++LLK GA + G TPL +A RV+ ++
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVL 184 HSP 3 Score: 79.7221 bits (195), Expect = 8.140e-15 Identity = 55/191 (28.80%), Postives = 89/191 (46.60%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
+ F ++ A+K+G+L+ ++L L++G VD + T L AAHY N +++ L+ + AD NAK +TPLH +A G +I LLI NG+ V AKA NG T + + V + L GA+I + + G TPL +A ++ +N++K V+
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQ---LNMVKFLVE 743 HSP 4 Score: 77.7962 bits (190), Expect = 3.562e-14 Identity = 53/154 (34.42%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
AA+ +D+ + L VD Y T L AAH G++ + L++ AD N++ +TPLH A I +VELL+ A ++A +G TPL A N+V +LL++GA +E +G TPL LA + V+ ++ AKVDA
Sbjct: 333 AAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486 HSP 5 Score: 70.4774 bits (171), Expect = 4.998e-12 Identity = 71/295 (24.07%), Postives = 122/295 (41.36%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNG 989
L+ D +++ +L+ G + IN + NG L +A+ E + ++ L+ A D +G +A+ IA+ G L + GA++ + +NG LY E H+E ++ L++ + ++DG T L A + G K++ +LL++ +P++ K +G TPL A G ++ L+ G + N RH + +H A K G L + GA D P+H AA +GH L +G K NG
Sbjct: 38 LRAARAGDLEKVLELLRAGTD--INTSNA-NGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ--ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSK-SGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNG 326 HSP 6 Score: 65.855 bits (159), Expect = 1.458e-10 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 168 ILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINY-----NEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+L+ R ++ T E + G +++ Y PD G+T L +A N D ++ L+ GA D E ++ + IA++ G+ L +AGA+ + + L+ ++ E +E L +N D ++K G T L A + G N E+ +LL+ G P I+ TPL A + + L+ G A ++G T +H AAK + L F A + P+H +A GH L + G + K +NG
Sbjct: 411 LLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYG--NLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNG 689 HSP 7 Score: 64.6994 bits (156), Expect = 3.579e-10 Identity = 60/259 (23.17%), Postives = 107/259 (41.31%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG T L IA +N + ++ LL A + G + + +AA G + L + GA+ + + G+ L+ + + + +R ++ +++ +T L A G N +I ++LL+ GA+ N + +PL A G + L D + G T +H A+K GN + + L G D+ Q P+H AA + L + G + K NG IA K + +++
Sbjct: 391 NGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQ--TDVVRVLIRNGAKVDAQARELQTPLHIASRLG--NTDIVILLLQAGANSNATTR-DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQ 644 HSP 8 Score: 62.003 bits (149), Expect = 2.490e-9 Identity = 52/192 (27.08%), Postives = 83/192 (43.23%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALR 854
NG T L IA +N ++ LL A P+ G + + ++AQ GH L + G+D+ NG ++ C E H + ++N+ + G T L AC G+ N + L+++GAD +A+ TPL A G + L+ G PN G+T + A + G + LR
Sbjct: 622 NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQ--EDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLN--MVKFLVENGADVGEKTRAS-YTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 9 Score: 53.1434 bits (126), Expect = 1.060e-6 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G + ++ +K+ +VD R TAL A+ G + L+ GA+VN + +TPL+ AA ++V+ L+ +GA +G TPL A++ VV LL+ +K
Sbjct: 73 ASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSK 190 HSP 10 Score: 52.7582 bits (125), Expect = 1.310e-6 Identity = 64/255 (25.10%), Postives = 105/255 (41.18%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA---DLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT--GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDC 1034
T L A + L+ GA G + + +AAQ HV + +L A D+ ++ L +V +C H + L + D N+ + +G T L AC+ K ++ +LLK+ A I+ T G TPL A G+ +I L+ G +P+ G+T +H AA++ + L GA+ D P+H A+ G+ L Q G N + IA +G ++
Sbjct: 295 TPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHC-----GHVRVAKLLLDRSADPNSRALNGFTPLHIACK--KNRIKVVELLLKYRA---AIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEV 539
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 111.694 bits (278), Expect = 1.487e-24 Identity = 154/639 (24.10%), Postives = 252/639 (39.44%), Query Frame = 3
Query: 291 CLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADL---------------KLNDLNGKNVLY-----------------YCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEI----CVMP---ESH------IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRT----FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
L IA ++D LL +PDV G + + IAA YGH + L + GA++ K N N+L +C + + H + ++ + ++ +K+G L A + ++ + LL H A + + TPL A G + L DPN+ +G T +H A K K + L + A + ++ P+H AA G + +L Q+G NP V+ GE +A D ++ +I R+ K+ L+ + T+IV L L NS + + L I K EE+ +L D N D T L KK L+L S + + P++I V P +H M ++ G K Y T L+ + +N EI + DP+ F ++ +A+ G + L ++ G V + TA+ A ++ + L N GA++N+K N +TPLH A H G +++V+ L+ NGA V K TPL +A + N V +LL+ GA + + G TPL +A V+ ++
Sbjct: 197 ALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARS-GHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG--DHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLI---RNGAKVDAQARELQTPLHIASRLGNTDIVI-LLLQAGANSNATTRDNYSPLHIAAKEG-QEEVAGILL---DHNADKT------LLTKKGFTPLHLASKY------GNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKKN--QMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 2 Score: 82.4185 bits (202), Expect = 1.344e-15 Identity = 48/145 (33.10%), Postives = 79/145 (54.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GDL+ + L+ G ++T + +L A+ G+ ++ LI A V+A T LH A+ +G IV +L+ NGA V+ +++NG TPL+ A + + VV++LLK GA + G TPL +A RV+ ++
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVL 184 HSP 3 Score: 79.7221 bits (195), Expect = 7.588e-15 Identity = 55/191 (28.80%), Postives = 89/191 (46.60%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
+ F ++ A+K+G+L+ ++L L++G VD + T L AAHY N +++ L+ + AD NAK +TPLH +A G +I LLI NG+ V AKA NG T + + V + L GA+I + + G TPL +A ++ +N++K V+
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQ---LNMVKFLVE 743 HSP 4 Score: 77.7962 bits (190), Expect = 3.676e-14 Identity = 53/154 (34.42%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
AA+ +D+ + L VD Y T L AAH G++ + L++ AD N++ +TPLH A I +VELL+ A ++A +G TPL A N+V +LL++GA +E +G TPL LA + V+ ++ AKVDA
Sbjct: 333 AAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486 HSP 5 Score: 70.4774 bits (171), Expect = 5.658e-12 Identity = 71/295 (24.07%), Postives = 122/295 (41.36%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNG 989
L+ D +++ +L+ G + IN + NG L +A+ E + ++ L+ A D +G +A+ IA+ G L + GA++ + +NG LY E H+E ++ L++ + ++DG T L A + G K++ +LL++ +P++ K +G TPL A G ++ L+ G + N RH + +H A K G L + GA D P+H AA +GH L +G K NG
Sbjct: 38 LRAARAGDLEKVLELLRAGTD--INTSNA-NGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ--ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSK-SGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNG 326 HSP 6 Score: 65.4698 bits (158), Expect = 1.706e-10 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 168 ILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINY-----NEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+L+ R ++ T E + G +++ Y PD G+T L +A N D ++ L+ GA D E ++ + IA++ G+ L +AGA+ + + L+ ++ E +E L +N D ++K G T L A + G N E+ +LL+ G P I+ TPL A + + L+ G A ++G T +H AAK + L F A + P+H +A GH L + G + K +NG
Sbjct: 411 LLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYG--NLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNG 689 HSP 7 Score: 64.3142 bits (155), Expect = 4.444e-10 Identity = 60/259 (23.17%), Postives = 107/259 (41.31%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG T L IA +N + ++ LL A + G + + +AA G + L + GA+ + + G+ L+ + + + +R ++ +++ +T L A G N +I ++LL+ GA+ N + +PL A G + L D + G T +H A+K GN + + L G D+ Q P+H AA + L + G + K NG IA K + +++
Sbjct: 391 NGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQ--TDVVRVLIRNGAKVDAQARELQTPLHIASRLG--NTDIVILLLQAGANSNATTR-DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQ 644 HSP 8 Score: 62.003 bits (149), Expect = 2.480e-9 Identity = 52/192 (27.08%), Postives = 83/192 (43.23%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALR 854
NG T L IA +N ++ LL A P+ G + + ++AQ GH L + G+D+ NG ++ C E H + ++N+ + G T L AC G+ N + L+++GAD +A+ TPL A G + L+ G PN G+T + A + G + LR
Sbjct: 622 NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQ--EDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLN--MVKFLVENGADVGEKTRAS-YTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 9 Score: 53.1434 bits (126), Expect = 1.011e-6 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G + ++ +K+ +VD R TAL A+ G + L+ GA+VN + +TPL+ AA ++V+ L+ +GA +G TPL A++ VV LL+ +K
Sbjct: 73 ASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSK 190 HSP 10 Score: 52.7582 bits (125), Expect = 1.638e-6 Identity = 64/255 (25.10%), Postives = 105/255 (41.18%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA---DLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT--GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDC 1034
T L A + L+ GA G + + +AAQ HV + +L A D+ ++ L +V +C H + L + D N+ + +G T L AC+ K ++ +LLK+ A I+ T G TPL A G+ +I L+ G +P+ G+T +H AA++ + L GA+ D P+H A+ G+ L Q G N + IA +G ++
Sbjct: 295 TPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHC-----GHVRVAKLLLDRSADPNSRALNGFTPLHIACK--KNRIKVVELLLKYRA---AIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEV 539
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 111.694 bits (278), Expect = 1.487e-24 Identity = 154/639 (24.10%), Postives = 252/639 (39.44%), Query Frame = 3
Query: 291 CLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADL---------------KLNDLNGKNVLY-----------------YCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEI----CVMP---ESH------IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRT----FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
L IA ++D LL +PDV G + + IAA YGH + L + GA++ K N N+L +C + + H + ++ + ++ +K+G L A + ++ + LL H A + + TPL A G + L DPN+ +G T +H A K K + L + A + ++ P+H AA G + +L Q+G NP V+ GE +A D ++ +I R+ K+ L+ + T+IV L L NS + + L I K EE+ +L D N D T L KK L+L S + + P++I V P +H M ++ G K Y T L+ + +N EI + DP+ F ++ +A+ G + L ++ G V + TA+ A ++ + L N GA++N+K N +TPLH A H G +++V+ L+ NGA V K TPL +A + N V +LL+ GA + + G TPL +A V+ ++
Sbjct: 197 ALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARS-GHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG--DHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLI---RNGAKVDAQARELQTPLHIASRLGNTDIVI-LLLQAGANSNATTRDNYSPLHIAAKEG-QEEVAGILL---DHNADKT------LLTKKGFTPLHLASKY------GNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKKN--QMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 2 Score: 82.4185 bits (202), Expect = 1.344e-15 Identity = 48/145 (33.10%), Postives = 79/145 (54.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GDL+ + L+ G ++T + +L A+ G+ ++ LI A V+A T LH A+ +G IV +L+ NGA V+ +++NG TPL+ A + + VV++LLK GA + G TPL +A RV+ ++
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVL 184 HSP 3 Score: 79.7221 bits (195), Expect = 7.588e-15 Identity = 55/191 (28.80%), Postives = 89/191 (46.60%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
+ F ++ A+K+G+L+ ++L L++G VD + T L AAHY N +++ L+ + AD NAK +TPLH +A G +I LLI NG+ V AKA NG T + + V + L GA+I + + G TPL +A ++ +N++K V+
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQ---LNMVKFLVE 743 HSP 4 Score: 77.7962 bits (190), Expect = 3.676e-14 Identity = 53/154 (34.42%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
AA+ +D+ + L VD Y T L AAH G++ + L++ AD N++ +TPLH A I +VELL+ A ++A +G TPL A N+V +LL++GA +E +G TPL LA + V+ ++ AKVDA
Sbjct: 333 AAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486 HSP 5 Score: 70.4774 bits (171), Expect = 5.658e-12 Identity = 71/295 (24.07%), Postives = 122/295 (41.36%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNG 989
L+ D +++ +L+ G + IN + NG L +A+ E + ++ L+ A D +G +A+ IA+ G L + GA++ + +NG LY E H+E ++ L++ + ++DG T L A + G K++ +LL++ +P++ K +G TPL A G ++ L+ G + N RH + +H A K G L + GA D P+H AA +GH L +G K NG
Sbjct: 38 LRAARAGDLEKVLELLRAGTD--INTSNA-NGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ--ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSK-SGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNG 326 HSP 6 Score: 65.4698 bits (158), Expect = 1.706e-10 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 168 ILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINY-----NEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+L+ R ++ T E + G +++ Y PD G+T L +A N D ++ L+ GA D E ++ + IA++ G+ L +AGA+ + + L+ ++ E +E L +N D ++K G T L A + G N E+ +LL+ G P I+ TPL A + + L+ G A ++G T +H AAK + L F A + P+H +A GH L + G + K +NG
Sbjct: 411 LLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYG--NLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNG 689 HSP 7 Score: 64.3142 bits (155), Expect = 4.444e-10 Identity = 60/259 (23.17%), Postives = 107/259 (41.31%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG T L IA +N + ++ LL A + G + + +AA G + L + GA+ + + G+ L+ + + + +R ++ +++ +T L A G N +I ++LL+ GA+ N + +PL A G + L D + G T +H A+K GN + + L G D+ Q P+H AA + L + G + K NG IA K + +++
Sbjct: 391 NGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQ--TDVVRVLIRNGAKVDAQARELQTPLHIASRLG--NTDIVILLLQAGANSNATTR-DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQ 644 HSP 8 Score: 62.003 bits (149), Expect = 2.480e-9 Identity = 52/192 (27.08%), Postives = 83/192 (43.23%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALR 854
NG T L IA +N ++ LL A P+ G + + ++AQ GH L + G+D+ NG ++ C E H + ++N+ + G T L AC G+ N + L+++GAD +A+ TPL A G + L+ G PN G+T + A + G + LR
Sbjct: 622 NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQ--EDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLN--MVKFLVENGADVGEKTRAS-YTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 9 Score: 53.1434 bits (126), Expect = 1.011e-6 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G + ++ +K+ +VD R TAL A+ G + L+ GA+VN + +TPL+ AA ++V+ L+ +GA +G TPL A++ VV LL+ +K
Sbjct: 73 ASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSK 190 HSP 10 Score: 52.7582 bits (125), Expect = 1.638e-6 Identity = 64/255 (25.10%), Postives = 105/255 (41.18%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA---DLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT--GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDC 1034
T L A + L+ GA G + + +AAQ HV + +L A D+ ++ L +V +C H + L + D N+ + +G T L AC+ K ++ +LLK+ A I+ T G TPL A G+ +I L+ G +P+ G+T +H AA++ + L GA+ D P+H A+ G+ L Q G N + IA +G ++
Sbjct: 295 TPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHC-----GHVRVAKLLLDRSADPNSRALNGFTPLHIACK--KNRIKVVELLLKYRA---AIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEV 539
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Match: unc-44 (AO49 ankyrin [Source:UniProtKB/TrEMBL;Acc:Q7JP86]) HSP 1 Score: 111.309 bits (277), Expect = 1.668e-24 Identity = 154/639 (24.10%), Postives = 252/639 (39.44%), Query Frame = 3
Query: 291 CLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADL---------------KLNDLNGKNVLY-----------------YCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEI----CVMP---ESH------IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRT----FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
L IA ++D LL +PDV G + + IAA YGH + L + GA++ K N N+L +C + + H + ++ + ++ +K+G L A + ++ + LL H A + + TPL A G + L DPN+ +G T +H A K K + L + A + ++ P+H AA G + +L Q+G NP V+ GE +A D ++ +I R+ K+ L+ + T+IV L L NS + + L I K EE+ +L D N D T L KK L+L S + + P++I V P +H M ++ G K Y T L+ + +N EI + DP+ F ++ +A+ G + L ++ G V + TA+ A ++ + L N GA++N+K N +TPLH A H G +++V+ L+ NGA V K TPL +A + N V +LL+ GA + + G TPL +A V+ ++
Sbjct: 197 ALHIAAKKDDTTAATLLLQNEHNPDVTSKSGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARS-GHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQG--DHVDAARTLLYHRAPVDDV-TVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLI---RNGAKVDAQARELQTPLHIASRLGNTDIVI-LLLQAGANSNATTRDNYSPLHIAAKEG-QEEVAGILL---DHNADKT------LLTKKGFTPLHLASKY------GNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGY-TPLHIAAKKN--QMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLNMVKFLVENGADVGEKTRASYTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 2 Score: 82.0333 bits (201), Expect = 1.574e-15 Identity = 48/145 (33.10%), Postives = 79/145 (54.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GDL+ + L+ G ++T + +L A+ G+ ++ LI A V+A T LH A+ +G IV +L+ NGA V+ +++NG TPL+ A + + VV++LLK GA + G TPL +A RV+ ++
Sbjct: 40 AARAGDLEKVLELLRAGTDINTSNANGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVL 184 HSP 3 Score: 79.7221 bits (195), Expect = 8.888e-15 Identity = 55/191 (28.80%), Postives = 89/191 (46.60%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
+ F ++ A+K+G+L+ ++L L++G VD + T L AAHY N +++ L+ + AD NAK +TPLH +A G +I LLI NG+ V AKA NG T + + V + L GA+I + + G TPL +A ++ +N++K V+
Sbjct: 556 KGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQEDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQ---LNMVKFLVE 743 HSP 4 Score: 77.411 bits (189), Expect = 4.024e-14 Identity = 53/154 (34.42%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
AA+ +D+ + L VD Y T L AAH G++ + L++ AD N++ +TPLH A I +VELL+ A ++A +G TPL A N+V +LL++GA +E +G TPL LA + V+ ++ AKVDA
Sbjct: 333 AAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHCGHVRVAKLLLDRSADPNSRALNGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDA 486 HSP 5 Score: 70.0922 bits (170), Expect = 6.518e-12 Identity = 71/295 (24.07%), Postives = 122/295 (41.36%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNG 989
L+ D +++ +L+ G + IN + NG L +A+ E + ++ L+ A D +G +A+ IA+ G L + GA++ + +NG LY E H+E ++ L++ + ++DG T L A + G K++ +LL++ +P++ K +G TPL A G ++ L+ G + N RH + +H A K G L + GA D P+H AA +GH L +G K NG
Sbjct: 38 LRAARAGDLEKVLELLRAGTD--INTSNA-NGLNSLHLASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQ--ENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSKGKVRLPALHIAAKKDDTTAATLLLQNEHNPDVTSK-SGFTPLHIAAHYGHENVGQLLLEKGANVNYQARHNISPLHVATKWGRTNMANLLLSRGAIIDSRTKDLLTPLHCAARSGHDQVVDLLVVQGAPISAKTKNG 326 HSP 6 Score: 65.4698 bits (158), Expect = 1.900e-10 Identity = 71/284 (25.00%), Postives = 119/284 (41.90%), Query Frame = 3
Query: 168 ILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINY-----NEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+L+ R ++ T E + G +++ Y PD G+T L +A N D ++ L+ GA D E ++ + IA++ G+ L +AGA+ + + L+ ++ E +E L +N D ++K G T L A + G N E+ +LL+ G P I+ TPL A + + L+ G A ++G T +H AAK + L F A + P+H +A GH L + G + K +NG
Sbjct: 411 LLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLH--IAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYG--NLEVVRLLLERGT-PVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNG 689 HSP 7 Score: 63.929 bits (154), Expect = 5.252e-10 Identity = 60/259 (23.17%), Postives = 107/259 (41.31%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG T L IA +N + ++ LL A + G + + +AA G + L + GA+ + + G+ L+ + + + +R ++ +++ +T L A G N +I ++LL+ GA+ N + +PL A G + L D + G T +H A+K GN + + L G D+ Q P+H AA + L + G + K NG IA K + +++
Sbjct: 391 NGFTPLHIACKKNRIKVVELLLKYRAAIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQ--TDVVRVLIRNGAKVDAQARELQTPLHIASRLG--NTDIVILLLQAGANSNATTR-DNYSPLHIAAKEGQEEVAGILLDHNADKTLLTKKGFTPLHLASKYGNLEVVRLLLERGTPVDIEGKNQVTPLHVAAHYNNDKVAMLLLENGASAKAAAKNGYTPLHIAAKKNQMEIASTLLQ 644 HSP 8 Score: 61.6178 bits (148), Expect = 2.906e-9 Identity = 52/192 (27.08%), Postives = 83/192 (43.23%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALR 854
NG T L IA +N ++ LL A P+ G + + ++AQ GH L + G+D+ NG ++ C E H + ++N+ + G T L AC G+ N + L+++GAD +A+ TPL A G + L+ G PN G+T + A + G + LR
Sbjct: 622 NGYTPLHIAAKKNQMEIASTLLQFKADPNAKSRAGFTPLHLSAQEGHKEISGLLIENGSDVGAKANNGLTAMHLCAQ--EDHVPVAQILYNNGAEINSKTNAGYTPLHVACHFGQLN--MVKFLVENGADVGEKTRAS-YTPLHQAAQQGHNNCVRYLLENGASPNEQTATGQTPLSIAQRLGYVSVVETLR 808 HSP 9 Score: 53.1434 bits (126), Expect = 1.089e-6 Identity = 36/118 (30.51%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G + ++ +K+ +VD R TAL A+ G + L+ GA+VN + +TPL+ AA ++V+ L+ +GA +G TPL A++ VV LL+ +K
Sbjct: 73 ASKEGHSEVVRELIKRQAQVDAATRKGNTALHIASLAGQSLIVTILVENGANVNVQSVNGFTPLYMAAQENHEEVVKYLLKHGANQALSTEDGFTPLAVALQQGHDRVVAVLLENDSK 190 HSP 10 Score: 52.373 bits (124), Expect = 1.856e-6 Identity = 64/255 (25.10%), Postives = 105/255 (41.18%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA---DLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT--GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDC 1034
T L A + L+ GA G + + +AAQ HV + +L A D+ ++ L +V +C H + L + D N+ + +G T L AC+ K ++ +LLK+ A I+ T G TPL A G+ +I L+ G +P+ G+T +H AA++ + L GA+ D P+H A+ G+ L Q G N + IA +G ++
Sbjct: 295 TPLHCAARSGHDQVVDLLVVQGAPISAKTKNGLAPLHMAAQGDHVDAARTLLYHRAPVDDVTVDYLTPLHVAAHC-----GHVRVAKLLLDRSADPNSRALNGFTPLHIACK--KNRIKVVELLLKYRA---AIEATTESGLTPLHVAAFMGAINIVIYLLQQGANPDVETVRGETPLHLAARANQTDVVRVLIRNGAKVDAQARELQTPLHIASRLGNTDIVILLLQAGANSNATTRDNYSPLHIAAKEGQEEV 539
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089172) HSP 1 Score: 110.538 bits (275), Expect = 3.191e-24 Identity = 152/609 (24.96%), Postives = 238/609 (39.08%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAA-CASGSTSIPSKCLKLGVDPNT--ADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPP-------------VMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
NG L +A + +D LL G D +G +A+ IA+ G L A++ + LNG LY ++ E H C T L + + ++DG T L A + G +++I +LL++ GK L A A+ + + L L DPN + G T +H AA GN L A + P+H A G S C L RG +G A G EVIK L + N P +T+ L L + G E LL+ KAP++E + G A L K ++ F KK +E+ + ++I + G V+Y+ + + S DL E P H AA+ D I++ L+ KVD R +T L A+ GN+++ M L+ +GA++NA+ N ++ LH AA G +IV++L+ NGA +A G TPL A + + NVV+ LL+ GA I + +TPL +A ++ + ++ ++
Sbjct: 72 NGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLY--MAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQG--HDKIVAVLLEN--------DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSG----HVEVIK------HLLQQNAPI-----------LTKTKNGLSALHMAAQG--EHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKM-------VELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLH----------------------LAARANQADIIRILLRSA-KVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELL 615 HSP 2 Score: 82.8037 bits (203), Expect = 1.168e-15 Identity = 63/214 (29.44%), Postives = 105/214 (49.07%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
G+T L +A N D I+ LL A D + EG++ + +A++ G++ L + GA++ + + L+ ++ E + ++ L + N V+K G T L AC+ GK+N + ILL++GA + Q TPL A + SI LK G PN R+G+ A+H A K + + L GA ++ + +P+H AA G
Sbjct: 465 GETPLHLAARANQADIIRILLR-SAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALH--IAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN--VVQILLQNGASIDF-QGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQG 672 HSP 3 Score: 78.1814 bits (191), Expect = 3.234e-14 Identity = 52/178 (29.21%), Postives = 81/178 (45.51%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
+ F ++ A K+G + +++ L+ G +D + + T L A HY N L++ M L+ +GADVN ++PLH AA G +D+V+LL+ G V+ A A NG TPL A + V + LL+ GA I G TPL +A ++
Sbjct: 562 KGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG-VISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYG 738 HSP 4 Score: 75.8702 bits (185), Expect = 1.466e-13 Identity = 57/154 (37.01%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1623 AKHGDLD-SIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--KAKVDAL 2075
A G+ D + L L VD Y TAL AAH G++ + L++Y A+ NA+ +TPLH A I +VELLI +GA + A +G TPL A N+V +LL+ A + +G TPL LA + +I I+ AKVDA+
Sbjct: 340 AAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAI 493 HSP 5 Score: 74.7146 bits (182), Expect = 3.667e-13 Identity = 86/340 (25.29%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 246 VEHLINYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKN-VLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKA-------------------------------TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMT-EIVEELKL 1160
++H N N K + L IA E + ++ LL+ GA + V +G + + +A +YG + L + GA + D GKN V V+ + +E L+ N +++G+ + AC+ K EI + LL+HGAD NII K+ G TPL A G + L+ G + + R+G T +H AA G+ + A ++ + P+H AA GH L + NP +G A IA + G M E +K+ S + N +G + ++ MT E+++E L
Sbjct: 517 LQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASI---DFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACK--KNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVM-ESLKIVTSTSVINSN-----IGAIEEKLKVMTPELMQETLL 845 HSP 6 Score: 67.781 bits (164), Expect = 4.661e-11 Identity = 44/152 (28.95%), Postives = 78/152 (51.32%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
F ++ AA+ G++D ++L L+ G + + T L AA G++ + L+ +GA+++ + +TPLH AAH G +D+V+ I N A ++ + G TPL +A + ++ LL+ A G T L +A N V+ +K
Sbjct: 663 FSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLK 813 HSP 7 Score: 65.855 bits (159), Expect = 1.889e-10 Identity = 50/144 (34.72%), Postives = 72/144 (50.00%), Query Frame = 3
Query: 1680 DTRDRFYKTALMSAAHYGNLDMCMHLINY--GADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
D R + AL AA +++ L+ + AD+ +K F TPLH AAH G +DI LL+NN A V+ A + TPL A + + ++ LL +GAKI GLTPL A + S + +IK + P+ K G
Sbjct: 195 DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGF--TPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCA---SRSGHVEVIKHLLQQNAPILTKTKNG 333 HSP 8 Score: 63.1586 bits (152), Expect = 1.112e-9 Identity = 69/232 (29.74%), Postives = 105/232 (45.26%), Query Frame = 3
Query: 246 VEHLINYN-----EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVL-YYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
+ LI YN + NG T L +A EN + + LL GA+P + +G + + +A Q GH K A L ND+ GK L ++ + + L+++ + + VSK G T L A G N +I +LL + AD N + K TPL AC G S+ + L G + A R G T +H A++SG+ + + L A + +H AA G
Sbjct: 122 INQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGH-------DKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYG--NVDIATLLLNNKADVNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQG 343 HSP 9 Score: 60.4622 bits (145), Expect = 7.487e-9 Identity = 42/147 (28.57%), Postives = 71/147 (48.30%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GD+ + L G +++ + AL AA G +D+C L+ G ++ T LH A+ +G D++ LI A V+ ++LNG TPL+ A + + N LL GA + G TPL +A +++ ++
Sbjct: 45 AARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVL 191 HSP 10 Score: 60.077 bits (144), Expect = 1.078e-8 Identity = 40/145 (27.59%), Postives = 71/145 (48.97%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AAK G + +++ L+ G + + + T L A YG ++ L+ GA ++ + TPLH A H IVELL+ NG+ + A NG + A + + + LL+ GA + + + G +PL LA + ++ ++
Sbjct: 537 AAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL 681 HSP 11 Score: 53.5286 bits (127), Expect = 1.110e-6 Identity = 59/231 (25.54%), Postives = 93/231 (40.26%), Query Frame = 3
Query: 258 INYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFL 947
+NY N T L +A L LL GA D +G + + A++ GHV + L + A + NG + L+ ++ H E L ++ V+ D T L A G + ++ +LL + A+PN + G TPL AC + +K G + G T +H A+ G ++ L A D+ P+H AA A A + L
Sbjct: 260 VNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALH--MAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCG--HVKVAKLLLDYKANPNA-RALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRIL 484
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0300497) HSP 1 Score: 110.538 bits (275), Expect = 3.191e-24 Identity = 152/609 (24.96%), Postives = 238/609 (39.08%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAA-CASGSTSIPSKCLKLGVDPNT--ADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPP-------------VMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
NG L +A + +D LL G D +G +A+ IA+ G L A++ + LNG LY ++ E H C T L + + ++DG T L A + G +++I +LL++ GK L A A+ + + L L DPN + G T +H AA GN L A + P+H A G S C L RG +G A G EVIK L + N P +T+ L L + G E LL+ KAP++E + G A L K ++ F KK +E+ + ++I + G V+Y+ + + S DL E P H AA+ D I++ L+ KVD R +T L A+ GN+++ M L+ +GA++NA+ N ++ LH AA G +IV++L+ NGA +A G TPL A + + NVV+ LL+ GA I + +TPL +A ++ + ++ ++
Sbjct: 72 NGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLY--MAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQG--HDKIVAVLLEN--------DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSG----HVEVIK------HLLQQNAPI-----------LTKTKNGLSALHMAAQG--EHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKM-------VELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLH----------------------LAARANQADIIRILLRSA-KVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELL 615 HSP 2 Score: 82.8037 bits (203), Expect = 1.168e-15 Identity = 63/214 (29.44%), Postives = 105/214 (49.07%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
G+T L +A N D I+ LL A D + EG++ + +A++ G++ L + GA++ + + L+ ++ E + ++ L + N V+K G T L AC+ GK+N + ILL++GA + Q TPL A + SI LK G PN R+G+ A+H A K + + L GA ++ + +P+H AA G
Sbjct: 465 GETPLHLAARANQADIIRILLR-SAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALH--IAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN--VVQILLQNGASIDF-QGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQG 672 HSP 3 Score: 78.1814 bits (191), Expect = 3.234e-14 Identity = 52/178 (29.21%), Postives = 81/178 (45.51%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
+ F ++ A K+G + +++ L+ G +D + + T L A HY N L++ M L+ +GADVN ++PLH AA G +D+V+LL+ G V+ A A NG TPL A + V + LL+ GA I G TPL +A ++
Sbjct: 562 KGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG-VISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYG 738 HSP 4 Score: 75.8702 bits (185), Expect = 1.466e-13 Identity = 57/154 (37.01%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1623 AKHGDLD-SIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--KAKVDAL 2075
A G+ D + L L VD Y TAL AAH G++ + L++Y A+ NA+ +TPLH A I +VELLI +GA + A +G TPL A N+V +LL+ A + +G TPL LA + +I I+ AKVDA+
Sbjct: 340 AAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAI 493 HSP 5 Score: 74.7146 bits (182), Expect = 3.667e-13 Identity = 86/340 (25.29%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 246 VEHLINYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKN-VLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKA-------------------------------TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMT-EIVEELKL 1160
++H N N K + L IA E + ++ LL+ GA + V +G + + +A +YG + L + GA + D GKN V V+ + +E L+ N +++G+ + AC+ K EI + LL+HGAD NII K+ G TPL A G + L+ G + + R+G T +H AA G+ + A ++ + P+H AA GH L + NP +G A IA + G M E +K+ S + N +G + ++ MT E+++E L
Sbjct: 517 LQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASI---DFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACK--KNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVM-ESLKIVTSTSVINSN-----IGAIEEKLKVMTPELMQETLL 845 HSP 6 Score: 67.781 bits (164), Expect = 4.661e-11 Identity = 44/152 (28.95%), Postives = 78/152 (51.32%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
F ++ AA+ G++D ++L L+ G + + T L AA G++ + L+ +GA+++ + +TPLH AAH G +D+V+ I N A ++ + G TPL +A + ++ LL+ A G T L +A N V+ +K
Sbjct: 663 FSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLK 813 HSP 7 Score: 65.855 bits (159), Expect = 1.889e-10 Identity = 50/144 (34.72%), Postives = 72/144 (50.00%), Query Frame = 3
Query: 1680 DTRDRFYKTALMSAAHYGNLDMCMHLINY--GADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
D R + AL AA +++ L+ + AD+ +K F TPLH AAH G +DI LL+NN A V+ A + TPL A + + ++ LL +GAKI GLTPL A + S + +IK + P+ K G
Sbjct: 195 DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGF--TPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCA---SRSGHVEVIKHLLQQNAPILTKTKNG 333 HSP 8 Score: 63.1586 bits (152), Expect = 1.112e-9 Identity = 69/232 (29.74%), Postives = 105/232 (45.26%), Query Frame = 3
Query: 246 VEHLINYN-----EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVL-YYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
+ LI YN + NG T L +A EN + + LL GA+P + +G + + +A Q GH K A L ND+ GK L ++ + + L+++ + + VSK G T L A G N +I +LL + AD N + K TPL AC G S+ + L G + A R G T +H A++SG+ + + L A + +H AA G
Sbjct: 122 INQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGH-------DKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYG--NVDIATLLLNNKADVNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQG 343 HSP 9 Score: 60.4622 bits (145), Expect = 7.487e-9 Identity = 42/147 (28.57%), Postives = 71/147 (48.30%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GD+ + L G +++ + AL AA G +D+C L+ G ++ T LH A+ +G D++ LI A V+ ++LNG TPL+ A + + N LL GA + G TPL +A +++ ++
Sbjct: 45 AARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVL 191 HSP 10 Score: 60.077 bits (144), Expect = 1.078e-8 Identity = 40/145 (27.59%), Postives = 71/145 (48.97%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AAK G + +++ L+ G + + + T L A YG ++ L+ GA ++ + TPLH A H IVELL+ NG+ + A NG + A + + + LL+ GA + + + G +PL LA + ++ ++
Sbjct: 537 AAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL 681 HSP 11 Score: 53.5286 bits (127), Expect = 1.110e-6 Identity = 59/231 (25.54%), Postives = 93/231 (40.26%), Query Frame = 3
Query: 258 INYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFL 947
+NY N T L +A L LL GA D +G + + A++ GHV + L + A + NG + L+ ++ H E L ++ V+ D T L A G + ++ +LL + A+PN + G TPL AC + +K G + G T +H A+ G ++ L A D+ P+H AA A A + L
Sbjct: 260 VNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALH--MAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCG--HVKVAKLLLDYKANPNA-RALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRIL 484
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089171) HSP 1 Score: 110.538 bits (275), Expect = 3.191e-24 Identity = 152/609 (24.96%), Postives = 238/609 (39.08%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAA-CASGSTSIPSKCLKLGVDPNT--ADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPP-------------VMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
NG L +A + +D LL G D +G +A+ IA+ G L A++ + LNG LY ++ E H C T L + + ++DG T L A + G +++I +LL++ GK L A A+ + + L L DPN + G T +H AA GN L A + P+H A G S C L RG +G A G EVIK L + N P +T+ L L + G E LL+ KAP++E + G A L K ++ F KK +E+ + ++I + G V+Y+ + + S DL E P H AA+ D I++ L+ KVD R +T L A+ GN+++ M L+ +GA++NA+ N ++ LH AA G +IV++L+ NGA +A G TPL A + + NVV+ LL+ GA I + +TPL +A ++ + ++ ++
Sbjct: 72 NGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLY--MAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQG--HDKIVAVLLEN--------DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSG----HVEVIK------HLLQQNAPI-----------LTKTKNGLSALHMAAQG--EHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKM-------VELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLH----------------------LAARANQADIIRILLRSA-KVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELL 615 HSP 2 Score: 82.8037 bits (203), Expect = 1.168e-15 Identity = 63/214 (29.44%), Postives = 105/214 (49.07%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
G+T L +A N D I+ LL A D + EG++ + +A++ G++ L + GA++ + + L+ ++ E + ++ L + N V+K G T L AC+ GK+N + ILL++GA + Q TPL A + SI LK G PN R+G+ A+H A K + + L GA ++ + +P+H AA G
Sbjct: 465 GETPLHLAARANQADIIRILLR-SAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALH--IAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN--VVQILLQNGASIDF-QGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQG 672 HSP 3 Score: 78.1814 bits (191), Expect = 3.234e-14 Identity = 52/178 (29.21%), Postives = 81/178 (45.51%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
+ F ++ A K+G + +++ L+ G +D + + T L A HY N L++ M L+ +GADVN ++PLH AA G +D+V+LL+ G V+ A A NG TPL A + V + LL+ GA I G TPL +A ++
Sbjct: 562 KGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG-VISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYG 738 HSP 4 Score: 75.8702 bits (185), Expect = 1.466e-13 Identity = 57/154 (37.01%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1623 AKHGDLD-SIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--KAKVDAL 2075
A G+ D + L L VD Y TAL AAH G++ + L++Y A+ NA+ +TPLH A I +VELLI +GA + A +G TPL A N+V +LL+ A + +G TPL LA + +I I+ AKVDA+
Sbjct: 340 AAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAI 493 HSP 5 Score: 74.7146 bits (182), Expect = 3.667e-13 Identity = 86/340 (25.29%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 246 VEHLINYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKN-VLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKA-------------------------------TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMT-EIVEELKL 1160
++H N N K + L IA E + ++ LL+ GA + V +G + + +A +YG + L + GA + D GKN V V+ + +E L+ N +++G+ + AC+ K EI + LL+HGAD NII K+ G TPL A G + L+ G + + R+G T +H AA G+ + A ++ + P+H AA GH L + NP +G A IA + G M E +K+ S + N +G + ++ MT E+++E L
Sbjct: 517 LQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASI---DFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACK--KNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVM-ESLKIVTSTSVINSN-----IGAIEEKLKVMTPELMQETLL 845 HSP 6 Score: 67.781 bits (164), Expect = 4.661e-11 Identity = 44/152 (28.95%), Postives = 78/152 (51.32%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
F ++ AA+ G++D ++L L+ G + + T L AA G++ + L+ +GA+++ + +TPLH AAH G +D+V+ I N A ++ + G TPL +A + ++ LL+ A G T L +A N V+ +K
Sbjct: 663 FSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLK 813 HSP 7 Score: 65.855 bits (159), Expect = 1.889e-10 Identity = 50/144 (34.72%), Postives = 72/144 (50.00%), Query Frame = 3
Query: 1680 DTRDRFYKTALMSAAHYGNLDMCMHLINY--GADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
D R + AL AA +++ L+ + AD+ +K F TPLH AAH G +DI LL+NN A V+ A + TPL A + + ++ LL +GAKI GLTPL A + S + +IK + P+ K G
Sbjct: 195 DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGF--TPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCA---SRSGHVEVIKHLLQQNAPILTKTKNG 333 HSP 8 Score: 63.1586 bits (152), Expect = 1.112e-9 Identity = 69/232 (29.74%), Postives = 105/232 (45.26%), Query Frame = 3
Query: 246 VEHLINYN-----EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVL-YYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
+ LI YN + NG T L +A EN + + LL GA+P + +G + + +A Q GH K A L ND+ GK L ++ + + L+++ + + VSK G T L A G N +I +LL + AD N + K TPL AC G S+ + L G + A R G T +H A++SG+ + + L A + +H AA G
Sbjct: 122 INQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGH-------DKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYG--NVDIATLLLNNKADVNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQG 343 HSP 9 Score: 60.4622 bits (145), Expect = 7.487e-9 Identity = 42/147 (28.57%), Postives = 71/147 (48.30%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GD+ + L G +++ + AL AA G +D+C L+ G ++ T LH A+ +G D++ LI A V+ ++LNG TPL+ A + + N LL GA + G TPL +A +++ ++
Sbjct: 45 AARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVL 191 HSP 10 Score: 60.077 bits (144), Expect = 1.078e-8 Identity = 40/145 (27.59%), Postives = 71/145 (48.97%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AAK G + +++ L+ G + + + T L A YG ++ L+ GA ++ + TPLH A H IVELL+ NG+ + A NG + A + + + LL+ GA + + + G +PL LA + ++ ++
Sbjct: 537 AAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL 681 HSP 11 Score: 53.5286 bits (127), Expect = 1.110e-6 Identity = 59/231 (25.54%), Postives = 93/231 (40.26%), Query Frame = 3
Query: 258 INYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFL 947
+NY N T L +A L LL GA D +G + + A++ GHV + L + A + NG + L+ ++ H E L ++ V+ D T L A G + ++ +LL + A+PN + G TPL AC + +K G + G T +H A+ G ++ L A D+ P+H AA A A + L
Sbjct: 260 VNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALH--MAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCG--HVKVAKLLLDYKANPNA-RALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRIL 484
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Match: Ank (gene:FBgn0011747 transcript:FBtr0089173) HSP 1 Score: 110.538 bits (275), Expect = 3.191e-24 Identity = 152/609 (24.96%), Postives = 238/609 (39.08%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAA-CASGSTSIPSKCLKLGVDPNT--ADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPP-------------VMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
NG L +A + +D LL G D +G +A+ IA+ G L A++ + LNG LY ++ E H C T L + + ++DG T L A + G +++I +LL++ GK L A A+ + + L L DPN + G T +H AA GN L A + P+H A G S C L RG +G A G EVIK L + N P +T+ L L + G E LL+ KAP++E + G A L K ++ F KK +E+ + ++I + G V+Y+ + + S DL E P H AA+ D I++ L+ KVD R +T L A+ GN+++ M L+ +GA++NA+ N ++ LH AA G +IV++L+ NGA +A G TPL A + + NVV+ LL+ GA I + +TPL +A ++ + ++ ++
Sbjct: 72 NGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLY--MAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQG--HDKIVAVLLEN--------DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSG----HVEVIK------HLLQQNAPI-----------LTKTKNGLSALHMAAQG--EHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKM-------VELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLH----------------------LAARANQADIIRILLRSA-KVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELL 615 HSP 2 Score: 82.8037 bits (203), Expect = 1.168e-15 Identity = 63/214 (29.44%), Postives = 105/214 (49.07%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
G+T L +A N D I+ LL A D + EG++ + +A++ G++ L + GA++ + + L+ ++ E + ++ L + N V+K G T L AC+ GK+N + ILL++GA + Q TPL A + SI LK G PN R+G+ A+H A K + + L GA ++ + +P+H AA G
Sbjct: 465 GETPLHLAARANQADIIRILLR-SAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALH--IAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN--VVQILLQNGASIDF-QGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQG 672 HSP 3 Score: 78.1814 bits (191), Expect = 3.234e-14 Identity = 52/178 (29.21%), Postives = 81/178 (45.51%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGN---------------------------------LDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
+ F ++ A K+G + +++ L+ G +D + + T L A HY N L++ M L+ +GADVN ++PLH AA G +D+V+LL+ G V+ A A NG TPL A + V + LL+ GA I G TPL +A ++
Sbjct: 562 KGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG-VISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYG 738 HSP 4 Score: 75.8702 bits (185), Expect = 1.466e-13 Identity = 57/154 (37.01%), Postives = 80/154 (51.95%), Query Frame = 3
Query: 1623 AKHGDLD-SIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--KAKVDAL 2075
A G+ D + L L VD Y TAL AAH G++ + L++Y A+ NA+ +TPLH A I +VELLI +GA + A +G TPL A N+V +LL+ A + +G TPL LA + +I I+ AKVDA+
Sbjct: 340 AAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAI 493 HSP 5 Score: 74.7146 bits (182), Expect = 3.667e-13 Identity = 86/340 (25.29%), Postives = 140/340 (41.18%), Query Frame = 3
Query: 246 VEHLINYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKN-VLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKA-------------------------------TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMT-EIVEELKL 1160
++H N N K + L IA E + ++ LL+ GA + V +G + + +A +YG + L + GA + D GKN V V+ + +E L+ N +++G+ + AC+ K EI + LL+HGAD NII K+ G TPL A G + L+ G + + R+G T +H AA G+ + A ++ + P+H AA GH L + NP +G A IA + G M E +K+ S + N +G + ++ MT E+++E L
Sbjct: 517 LQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASI---DFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACK--KNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVM-ESLKIVTSTSVINSN-----IGAIEEKLKVMTPELMQETLL 845 HSP 6 Score: 67.781 bits (164), Expect = 4.661e-11 Identity = 44/152 (28.95%), Postives = 78/152 (51.32%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
F ++ AA+ G++D ++L L+ G + + T L AA G++ + L+ +GA+++ + +TPLH AAH G +D+V+ I N A ++ + G TPL +A + ++ LL+ A G T L +A N V+ +K
Sbjct: 663 FSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLK 813 HSP 7 Score: 65.855 bits (159), Expect = 1.889e-10 Identity = 50/144 (34.72%), Postives = 72/144 (50.00%), Query Frame = 3
Query: 1680 DTRDRFYKTALMSAAHYGNLDMCMHLINY--GADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
D R + AL AA +++ L+ + AD+ +K F TPLH AAH G +DI LL+NN A V+ A + TPL A + + ++ LL +GAKI GLTPL A + S + +IK + P+ K G
Sbjct: 195 DVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGF--TPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCA---SRSGHVEVIKHLLQQNAPILTKTKNG 333 HSP 8 Score: 63.1586 bits (152), Expect = 1.112e-9 Identity = 69/232 (29.74%), Postives = 105/232 (45.26%), Query Frame = 3
Query: 246 VEHLINYN-----EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVL-YYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG 923
+ LI YN + NG T L +A EN + + LL GA+P + +G + + +A Q GH K A L ND+ GK L ++ + + L+++ + + VSK G T L A G N +I +LL + AD N + K TPL AC G S+ + L G + A R G T +H A++SG+ + + L A + +H AA G
Sbjct: 122 INQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGH-------DKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYG--NVDIATLLLNNKADVNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQG 343 HSP 9 Score: 60.4622 bits (145), Expect = 7.487e-9 Identity = 42/147 (28.57%), Postives = 71/147 (48.30%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ GD+ + L G +++ + AL AA G +D+C L+ G ++ T LH A+ +G D++ LI A V+ ++LNG TPL+ A + + N LL GA + G TPL +A +++ ++
Sbjct: 45 AARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVL 191 HSP 10 Score: 60.077 bits (144), Expect = 1.078e-8 Identity = 40/145 (27.59%), Postives = 71/145 (48.97%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AAK G + +++ L+ G + + + T L A YG ++ L+ GA ++ + TPLH A H IVELL+ NG+ + A NG + A + + + LL+ GA + + + G +PL LA + ++ ++
Sbjct: 537 AAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL 681 HSP 11 Score: 53.5286 bits (127), Expect = 1.110e-6 Identity = 59/231 (25.54%), Postives = 93/231 (40.26%), Query Frame = 3
Query: 258 INYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFL 947
+NY N T L +A L LL GA D +G + + A++ GHV + L + A + NG + L+ ++ H E L ++ V+ D T L A G + ++ +LL + A+PN + G TPL AC + +K G + G T +H A+ G ++ L A D+ P+H AA A A + L
Sbjct: 260 VNYVAKHN-ITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALH--MAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCG--HVKVAKLLLDYKANPNA-RALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRIL 484
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Match: CG10011 (gene:FBgn0039590 transcript:FBtr0085319) HSP 1 Score: 106.686 bits (265), Expect = 6.726e-23 Identity = 74/266 (27.82%), Postives = 133/266 (50.00%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSP---TERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSF 1067
G+T L A D +K L++ GA + VD +G+++++ A+ GH E L + GA++ DL+G++ L CV+ + + + + T L + + + + DG + L + +G N E+C +LL++ ADP++ G+TPL AAC +G ++ L G + D G+T + A GN +++ L G D+ P+HYAA G C L + G ++ G+ A +A +G C++ ++ + SF
Sbjct: 1350 GRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSAL--CVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEG--NAEVCELLLENAADPDLAD-FMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSF 1610 HSP 2 Score: 71.633 bits (174), Expect = 3.393e-12 Identity = 81/303 (26.73%), Postives = 132/303 (43.56%), Query Frame = 3
Query: 204 EKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLA---KAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGK--LGKNNEP 1094
+ + + +++L+D G++ N G T L A E + LL+ GA D D EGK+A+ +AAQ G + ++L + D K +D GK + ++ E H + +E L++ D+N+ D +T L+ + K E + +L D NI + G+T L A G + ++ G D N+ D +T +H A GN + L +GA D + +A GH C L Q G NP + G +A AK ++K+ S+ K NEP
Sbjct: 1528 QGNVETVRQLLDRGLDETHRDNA---GWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHD--GKTA--FRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKL-EIVKYLLDMTNVDVNI-PDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLA----AKSSRTSILKIFESYTKNEASNPNEP 1817 HSP 3 Score: 65.855 bits (159), Expect = 1.786e-10 Identity = 53/168 (31.55%), Postives = 86/168 (51.19%), Query Frame = 3
Query: 1611 MNDAAKHGDLDSIKLALKK-GYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAI---ESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGR 2102
+ A+ G + ++L + + K+D D+ +TAL +AA G+ D+ LI GADVN+ D T L A++ G DIVE+L+ NGA V+ L+G + L A S V+ LL GA ++ G++PL ++ ++ V ++ A P + D GR
Sbjct: 1320 LRSASWGGHSEVVRLLIAQPACKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENA-ADPDLADFMGR 1486 HSP 4 Score: 65.0846 bits (157), Expect = 3.638e-10 Identity = 44/128 (34.38%), Postives = 64/128 (50.00%), Query Frame = 3
Query: 1677 VDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKA 2060
V+ D +TAL AA G+ DM LI GADVN+ D TPLH A G D++ +L+ GA+ D GAT L + + V LL+ GA + G TP+ LA + + ++ I ++
Sbjct: 1678 VNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSILKIFES 1805 HSP 5 Score: 64.6994 bits (156), Expect = 4.346e-10 Identity = 38/113 (33.63%), Postives = 55/113 (48.67%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLL 1958
A G +KL L G +D D +T L A GN++ L++ G D +DN WTPLH+AA G ++ L+ +GA +D G T L A + R + V+ LL
Sbjct: 1492 ACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALL 1604 HSP 6 Score: 61.2326 bits (147), Expect = 5.191e-9 Identity = 71/282 (25.18%), Postives = 119/282 (42.20%), Query Frame = 3
Query: 228 KLVDNGVEHLINYNEPDN-GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLG---VDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYD-DTQNNPIHYAAAGHASCCKF-LGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKV 1055
K++ ++H N ++ DN G + L +++ E + + + LL+ A PD+ DF G++ + A GH + L G + D G+ VL + + + E + L +D + G T L +A +G E+CL LL+ GA + GKT L A G L + VD D GKTA A G+ ++ L F + D D++ A K+ L + + +S G A +A +G D +K +I+
Sbjct: 1433 KVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVL--SIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGF--HEVCLQLLESGAKIDECDNE-GKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHD--GKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEA 1707 HSP 7 Score: 59.3066 bits (142), Expect = 1.879e-8 Identity = 44/148 (29.73%), Postives = 75/148 (50.68%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAA---HSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA G D +KL ++ G V++ DR +T+L++A++ G+ D+ L+ GA+VN D + L AA SG ++ L+++GA D +G +PL + V E LL+ A + + G TPL A + V+ ++
Sbjct: 1357 AAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLL 1504 HSP 8 Score: 55.4546 bits (132), Expect = 2.840e-7 Identity = 74/331 (22.36%), Postives = 134/331 (40.48%), Query Frame = 3
Query: 312 ENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVA------SFES----------------------------------------LAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAAC---ASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYA-AAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEEL 1154
E L+ K +DL ++ D+ G++A+ IAA+ GH+ SF +A+ + L D G+ L + H++ L+ + D+N+V + G+T L A G + +I ILL++GA+ N + G++ L A +SG + + S L G + + D G + + ++ GN + L A D+ D P+ A AGHA+ K L GC +S G +I +G + +++++ +R + ++N W L+ E E+ +L
Sbjct: 1252 ERALNACKSPIDL----EIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGGHSEVVRLLIAQPACKIDLADKEGRTALR--AAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMG--HYDIVEILLENGANVNHLD-LDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLL--DRGLDETHRDNAGWT-PLHYAAFEGFHEVCLQL 1570 HSP 9 Score: 51.6026 bits (122), Expect = 4.514e-6 Identity = 50/184 (27.17%), Postives = 84/184 (45.65%), Query Frame = 3
Query: 378 EGKSAIMIAAQYGHVASFE---SLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYN------------VDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYD 884
+GK+ I I A G+ E + K+ DL++ D NG+ L ++ H E ++ L ++ VD+N+ +DG T L A G + E+ +L+ A + G+T L AA SG I ++ G D N+ DR G+T++ A+ G++ + L GA + D
Sbjct: 1234 KGKALIHILANDGNHQLLERALNACKSPIDLEIEDYNGQTALN--IAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGG--HSEVVRLLIAQPACKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLD 1413
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Match: ankef1a (ankyrin repeat and EF-hand domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-041001-196]) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 320/787 (40.66%), Postives = 451/787 (57.31%), Query Frame = 3
Query: 150 AQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKL--GKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGI--VNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKK-----------------GRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
A+ RL++LQI ++LQC + D I+KL+ GV+ LIN EP +G L +A N D ++FL+D GA PDV D G++ +M+AA+ G+ LAK AD+KL D+ GK VL+YC+ PT+RH CL+ L N D+NNVS+ G V ACE ++ E +CL +L+ GADPN + TG+T LM A +G+ + LK G + N D+ A H+AA+ G F+ + L A+ A + P+H+AA+G + CC+FL QRGCNPK+KN G R IAKD G K +KE+ K ER GK G N PWAL L+DW+ EN E+ + G+ V K FV +L L APL++ +L DK ++G + DFL G KY+ K Y+M+++ KKKK K GK K K +P+ IC +P+ I R DGGPP I Q++TD R+ ++ P IEDD +WYI +P++ ++N+N K GD++S++LAL + VD +DRFYKT LM+A GN +M L++ GADVNA D F WTPLHHA H+G +DI++LL+ GA VD ALNGATPL RAIES R + VE+L+K GAKI N LD+A+ +AD RV+++++AK++ P KD K G +K G + + S K + S +++ R N L DISF PR N L+ RRQRF +E+DF D+F+ F+KN+ ++ L D
Sbjct: 6 AKGRLQVLQIYRLLQCIQDGDKTYIEKLISMGVDDLINLTEPRDGNGVLHLAAVTNKPDMLEFLVDQGARPDVQDRSGRTPLMLAAELGYDGIVSLLAKKNADMKLVDIEGKGVLFYCLHPTKRHMRCLQVVLNGNADVNNVSEAGIPVFLLACEQAQDCEGMCLSILERGADPNATNQETGRTALMEAARAGALELVRAILKKGGNVNALDKKRFHAAHFAAEKGFFEIIKVLSAYRADVGGVTTEGDTPLHFAASGGYTDCCRFLAQRGCNPKLKNQEGLLPRQIAKDCGHKATVKELKKAERLHGKSSKGGTNGPWALMLHDWSHENENELRSAFESATDGFIGVEFVPKGTFVSVLKELHAPLDDVQIHILLLALDKRREGFININDFLRGLKYLPKTYVMASYGPKKKKAAKAGKTKKSKFNLPLPICTVPQDLIHRRDDGGPPHFMIESWQHATDTQRYDRDHRPERPIEDDTAWYIDEPEKIYINLNYCVKTGDIESLRLALSQKVPVDVKDRFYKTPLMAACASGNYEMAKFLLDNGADVNACDQFKWTPLHHACHAGQLDIIQLLLEAGASVDRPALNGATPLMRAIESCRPSCVEYLIKAGAKINAVNKTEQNCLDVAHAYADFRVVDLLQAKINTQPRPKDNKKPQPVKIHHKPTPASTPGSIKEKQGPVPTPTASSNSAVKKAMKKDSVIVHS-TQITSGRLNKL-----------DISFVPRTNWQNHLTTRDLMDRMARRRQRFSFEVDF-DDFKMPFNKNIQKKSMEFELTD 779
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Match: ankef1a (ankyrin repeat and EF-hand domain containing 1a [Source:ZFIN;Acc:ZDB-GENE-041001-196]) HSP 1 Score: 555.058 bits (1429), Expect = 0.000e+0 Identity = 320/787 (40.66%), Postives = 451/787 (57.31%), Query Frame = 3
Query: 150 AQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKL--GKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGI--VNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKK-----------------GRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
A+ RL++LQI ++LQC + D I+KL+ GV+ LIN EP +G L +A N D ++FL+D GA PDV D G++ +M+AA+ G+ LAK AD+KL D+ GK VL+YC+ PT+RH CL+ L N D+NNVS+ G V ACE ++ E +CL +L+ GADPN + TG+T LM A +G+ + LK G + N D+ A H+AA+ G F+ + L A+ A + P+H+AA+G + CC+FL QRGCNPK+KN G R IAKD G K +KE+ K ER GK G N PWAL L+DW+ EN E+ + G+ V K FV +L L APL++ +L DK ++G + DFL G KY+ K Y+M+++ KKKK K GK K K +P+ IC +P+ I R DGGPP I Q++TD R+ ++ P IEDD +WYI +P++ ++N+N K GD++S++LAL + VD +DRFYKT LM+A GN +M L++ GADVNA D F WTPLHHA H+G +DI++LL+ GA VD ALNGATPL RAIES R + VE+L+K GAKI N LD+A+ +AD RV+++++AK++ P KD K G +K G + + S K + S +++ R N L DISF PR N L+ RRQRF +E+DF D+F+ F+KN+ ++ L D
Sbjct: 6 AKGRLQVLQIYRLLQCIQDGDKTYIEKLISMGVDDLINLTEPRDGNGVLHLAAVTNKPDMLEFLVDQGARPDVQDRSGRTPLMLAAELGYDGIVSLLAKKNADMKLVDIEGKGVLFYCLHPTKRHMRCLQVVLNGNADVNNVSEAGIPVFLLACEQAQDCEGMCLSILERGADPNATNQETGRTALMEAARAGALELVRAILKKGGNVNALDKKRFHAAHFAAEKGFFEIIKVLSAYRADVGGVTTEGDTPLHFAASGGYTDCCRFLAQRGCNPKLKNQEGLLPRQIAKDCGHKATVKELKKAERLHGKSSKGGTNGPWALMLHDWSHENENELRSAFESATDGFIGVEFVPKGTFVSVLKELHAPLDDVQIHILLLALDKRREGFININDFLRGLKYLPKTYVMASYGPKKKKAAKAGKTKKSKFNLPLPICTVPQDLIHRRDDGGPPHFMIESWQHATDTQRYDRDHRPERPIEDDTAWYIDEPEKIYINLNYCVKTGDIESLRLALSQKVPVDVKDRFYKTPLMAACASGNYEMAKFLLDNGADVNACDQFKWTPLHHACHAGQLDIIQLLLEAGASVDRPALNGATPLMRAIESCRPSCVEYLIKAGAKINAVNKTEQNCLDVAHAYADFRVVDLLQAKINTQPRPKDNKKPQPVKIHHKPTPASTPGSIKEKQGPVPTPTASSNSAVKKAMKKDSVIVHS-TQITSGRLNKL-----------DISFVPRTNWQNHLTTRDLMDRMARRRQRFSFEVDF-DDFKMPFNKNIQKKSMEFELTD 779
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Match: ankef1b (ankyrin repeat and EF-hand domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-060810-68]) HSP 1 Score: 456.833 bits (1174), Expect = 3.213e-149 Identity = 261/661 (39.49%), Postives = 384/661 (58.09%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLG-----KNNEPWALGLYDWTVENMTEIVEELKLLDLENSGI--VNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIP-IEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
+A+S +EILQI K+LQ EK+ QIKK+V GV +LIN EP +G L AT + D + ++FLL L AHPD D +G + +M+AAQ G+ L K AD+ D GK VL+YC+SP++ H CL+ AL + NNVS GK +L ACE K+ E++C+ +L+ GADP+ + + T + LM A +G+ + K G +PN D G+ A H+AA+ G + L L A+ A F V N P+H+AAA GCNPK++N G+ +AK G K +KE+ K E+ K NEPWA+ L+DW+ E+ + + N + V+ + F+ LL +AP++ E ++I+ Q DKN + +F G KY+ K +++S++ K KK+KG K K R + IC+MP I + D G P I Q T F+ + P + IE+D +WYI +P++ + N+N + GDL+S++LA + VD +D+FYKT L++A GN + LI+ GADVNA D F WTPLHHA H+G +DI+ +L+ +GAVVDA A+NGATPL RAIES RF+ VE L+ GA + EN +G LD+A + ++R++ +I +KV LP K+ G+G
Sbjct: 16 MAKSNVEILQIYKLLQHVREKNKPQIKKIVCTGVFNLINLTEPKHGLGALYQATVDKDEELVQFLLSLRAHPDTQDKKGCTPLMLAAQLGYYNIVHILIKGYADVNCTDKEGKGVLFYCISPSKEHALCLQMALASKANFNNVSNSGKPLLVFACEKAKDCEDLCINILEKGADPDAVDQVTRCSALMEASKAGALKLVRAISKKGGNPNLVDVEGRCAAHFAAEGGFLEVLQVLSAYSADFCVSTTNGNTPLHFAAA------------GCNPKLRNLEGQLPSQVAKSNGHKAALKELKKAEKRHVKFSAPDAINPNEPWAITLHDWSCEHEAALRRSFESAVELNKPVQTVSLETFMSLLSTNQAPVSNENLQRIIKQHDKNHKNVINLNEFFKGLKYLQKPFVISSYAPKPAKKEKGPKEKKRNKCTSLLPICMMPPELICKREDSGLPYYMIEICQLYTHTKPFNRDQPSIHHIENDSAWYI-EPEKIYSNINYCVRSGDLESLRLAFAQQVPVDIKDQFYKTPLLTACSCGNYQVAEFLISLGADVNAVDQFSWTPLHHACHAGHVDIINMLVQSGAVVDAVAMNGATPLMRAIESCRFSSVECLITAGANVMAENKQGQNCLDIAMIYGNARIVQLITSKVKNLPKNKN-NGKG 662
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Match: ankef1b (ankyrin repeat and EF-hand domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-060810-68]) HSP 1 Score: 456.833 bits (1174), Expect = 3.213e-149 Identity = 261/661 (39.49%), Postives = 384/661 (58.09%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLG-----KNNEPWALGLYDWTVENMTEIVEELKLLDLENSGI--VNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIP-IEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
+A+S +EILQI K+LQ EK+ QIKK+V GV +LIN EP +G L AT + D + ++FLL L AHPD D +G + +M+AAQ G+ L K AD+ D GK VL+YC+SP++ H CL+ AL + NNVS GK +L ACE K+ E++C+ +L+ GADP+ + + T + LM A +G+ + K G +PN D G+ A H+AA+ G + L L A+ A F V N P+H+AAA GCNPK++N G+ +AK G K +KE+ K E+ K NEPWA+ L+DW+ E+ + + N + V+ + F+ LL +AP++ E ++I+ Q DKN + +F G KY+ K +++S++ K KK+KG K K R + IC+MP I + D G P I Q T F+ + P + IE+D +WYI +P++ + N+N + GDL+S++LA + VD +D+FYKT L++A GN + LI+ GADVNA D F WTPLHHA H+G +DI+ +L+ +GAVVDA A+NGATPL RAIES RF+ VE L+ GA + EN +G LD+A + ++R++ +I +KV LP K+ G+G
Sbjct: 16 MAKSNVEILQIYKLLQHVREKNKPQIKKIVCTGVFNLINLTEPKHGLGALYQATVDKDEELVQFLLSLRAHPDTQDKKGCTPLMLAAQLGYYNIVHILIKGYADVNCTDKEGKGVLFYCISPSKEHALCLQMALASKANFNNVSNSGKPLLVFACEKAKDCEDLCINILEKGADPDAVDQVTRCSALMEASKAGALKLVRAISKKGGNPNLVDVEGRCAAHFAAEGGFLEVLQVLSAYSADFCVSTTNGNTPLHFAAA------------GCNPKLRNLEGQLPSQVAKSNGHKAALKELKKAEKRHVKFSAPDAINPNEPWAITLHDWSCEHEAALRRSFESAVELNKPVQTVSLETFMSLLSTNQAPVSNENLQRIIKQHDKNHKNVINLNEFFKGLKYLQKPFVISSYAPKPAKKEKGPKEKKRNKCTSLLPICMMPPELICKREDSGLPYYMIEICQLYTHTKPFNRDQPSIHHIENDSAWYI-EPEKIYSNINYCVRSGDLESLRLAFAQQVPVDIKDQFYKTPLLTACSCGNYQVAEFLISLGADVNAVDQFSWTPLHHACHAGHVDIINMLVQSGAVVDAVAMNGATPLMRAIESCRFSSVECLITAGANVMAENKQGQNCLDIAMIYGNARIVQLITSKVKNLPKNKN-NGKG 662
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 115.161 bits (287), Expect = 2.108e-25 Identity = 137/611 (22.42%), Postives = 244/611 (39.93%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKE----QYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD 2069
N T L +A+ + + +K LLD G+ + +G + + A+ GH E L GA + NG + L+ H C++ L++N +++V+ D T L A G + ++ +++ A+PN + G TPL AC + LK G G T +H AA G+ + L GA + + +H AA AG ++L Q G +K + + A IA G + ++++++ K P A +T L S +E LL+ + L+ +K P K G + A+ L GK + L++ + ++ ++ + ++ P S P G ++I + + T L + +E C+ + ++ AA+ G +D + L L K V+ ++ T L AA + L+N+GA+++A+ +TPLH A H G + + L+ N A +AK NG TPL +A + +++ LL+ GA G T L +A V++ ++ D
Sbjct: 268 NDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGD--HLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCG--HYKVAKVIVDKKANPNA-KALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQ---------KGALPNAATTSGYT--------------PLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVAL------------LLLDQGASPHS----PAKNGYTPLHIAAKKNQLEIGTTLLEYGAE----------CNTVT---RQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYGNMKMANFLLENQAKPNAKTKNGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGVTD 821 HSP 2 Score: 84.3445 bits (207), Expect = 5.237e-16 Identity = 50/133 (37.59%), Postives = 73/133 (54.89%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
AA+ D S L L+ + D + T L AAHYGN+++ L+N GA V+ TPLH A+ G ++V+LL++ G+ ++AK +G TPL S VVE LL +GA I + GL+PL +A
Sbjct: 210 AARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMA 342 HSP 3 Score: 80.8777 bits (198), Expect = 5.500e-15 Identity = 45/145 (31.03%), Postives = 82/145 (56.55%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ G+L+ + LK G ++ ++ AL A+ G++++ L+ GA+V+A T LH A+ +G ++V L+ NGA V+A++ NG TPL+ A + + +VV FLL+ + + G TPL +A +V++++
Sbjct: 49 AARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLL 193 HSP 4 Score: 78.9518 bits (193), Expect = 2.175e-14 Identity = 49/151 (32.45%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
F ++ AA +G+++ L L +G VD R T L A+ GN +M L++ G+ + AK TPLH A SG +VE+L++ GA + +K NG +PL A + N V+ LL+ A + + LT L +A + +V +I
Sbjct: 237 FTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNAPVDDVTNDYLTALHVAAHCGHYKVAKVI 387 HSP 5 Score: 78.9518 bits (193), Expect = 2.735e-14 Identity = 64/209 (30.62%), Postives = 99/209 (47.37%), Query Frame = 3
Query: 1485 MYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLI--NYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
+Y+ ++ D+ RF +E++ S I D F + A + G + L L+ DT+ + AL AA + L+ ++ ADV +K F TPLH AAH G I++ LL+N GA VD A N TPL A + N+V+ LL +G+KI+ + GLTPL +V+ ++ +D P+ K G
Sbjct: 145 LYMAAQENHLDVVRFL--------LENNSSQSIATED-GFTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGF--TPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEML---LDRGAPILSKTKNG 335 HSP 6 Score: 78.1814 bits (191), Expect = 4.436e-14 Identity = 52/162 (32.10%), Postives = 80/162 (49.38%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
+ F ++ AAK+G L+ L L+K D + T L AAHY N + + L++ GA ++ +TPLH AA ++I L+ GA + G +PL A + ++V LL K A + M N GLTPL LA + V ++ A++DA
Sbjct: 565 KGFTPLHVAAKYGQLEVANLLLQKKAAPDAAGKSGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLHLAAQDDKAGVTEVLLNHGAEIDA 726 HSP 7 Score: 77.0258 bits (188), Expect = 1.054e-13 Identity = 68/257 (26.46%), Postives = 116/257 (45.14%), Query Frame = 3
Query: 237 DNGVEHLINYNEPDN-----GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+N V+ L ++ N G+T L +A +D +++LL GA D+ + ++A+ IA++ G + + L + GA +G L+ +S E H+E L L+ +K G T L A + G+ E+ +LL+ A P+ K +G TPL A + + L G P++ ++G T +H AAK + L +GA+ + +P+H AA G L + N + N NG
Sbjct: 447 ENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLH--LSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQL--EVANLLLQKKAAPDAAGK-SGLTPLHVAAHYDNQRVALLLLDQGASPHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNG 698 HSP 8 Score: 73.9442 bits (180), Expect = 8.861e-13 Identity = 49/160 (30.63%), Postives = 77/160 (48.12%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA G + +K G +T + +TAL AA G +D+ +L+ GA V+ K T LH A+ G ++IV+ L+ GA+ +A +G TPL + + LL++G+ + KG TPL +A + V N++ K A P K G
Sbjct: 441 AAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQIDVVRYLLQNGAKVDIKAKDDQTALHIASRLGKLEIVQQLLQKGALPNAATTSGYTPLHLSAREGHQEIAALLLEQGSSLSAATKKGFTPLHVAAKYGQLEVANLLLQK-KAAPDAAGKSG 599 HSP 9 Score: 72.7886 bits (177), Expect = 1.983e-12 Identity = 63/210 (30.00%), Postives = 96/210 (45.71%), Query Frame = 3
Query: 231 LVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAF 860
L+D G ++ NG T L IA +N L+ LL+ GA + V +G S + +AAQ G V L A++ + + NG L+ ++ + E L + +++ +K G T L AC G N ++ LL++ A PN K G TPL A G T I + L+ G PN +G TA+ A + G + LR
Sbjct: 618 LLDQGAS---PHSPAKNGYTPLHIAAKKNQLEIGTTLLEYGAECNTVTRQGISPLHLAAQEGSVDLVSLLLTKQANVNMGNKNGLTPLH--LAAQDDKAGVTEVLLNHGAEIDAQTKSGYTPLHVACHYG--NMKMANFLLENQAKPNAKTK-NGYTPLHQAAQQGHTHIINMLLQYGASPNELTLNGNTALSIARRLGYISVVDTLRGV 819 HSP 10 Score: 68.5514 bits (166), Expect = 4.022e-11 Identity = 69/288 (23.96%), Postives = 119/288 (41.32%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLK--HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
NG L +A+ E ++ + LL LGA+ D +G +A+ IA+ G L GA++ NG LY ++ E H + + L N + ++DG T L A + G K++ + +LL+ H AD ++ +G TPL A G+ ++ + L G + R+ T +H A+K GN + L G++ + P+H A +GH + L RG K NG +A +C++ +++
Sbjct: 74 NGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLY--MAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNAD---VESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGNMVKLLLDRGSKIEAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQ 356 HSP 11 Score: 64.6994 bits (156), Expect = 5.954e-10 Identity = 53/202 (26.24%), Postives = 84/202 (41.58%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK-----------------------------IQMENSKGLTPLDLAYNWADSRVINII---------KAKVDALP-PVKDKKGRGN 2108
A+K G ++ + LK G VD + TAL A+ G ++ L+ GA+VNA+ +TPL+ AA +D+V L+ N + +G TPL A++ VV LL+ K +E+ G TPL +A ++ + V ++ A+ D P V K+G GN
Sbjct: 82 ASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMAAQENHLDVVRFLLENNSSQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVASKRGNGN 283 HSP 12 Score: 56.225 bits (134), Expect = 1.905e-7 Identity = 37/123 (30.08%), Postives = 61/123 (49.59%), Query Frame = 3
Query: 1662 KKGYKVDTRDRFYKT----ALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
K+ + +RD+ K+ + + AA GNL+ + + G D+N + LH A+ G +++V L+ GA VDA G T L A + + VV L+ GA + ++ G TPL +A
Sbjct: 26 KRKTRKHSRDQKKKSDSNASYLRAARAGNLEKVLDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGANVDAATKKGNTALHIASLAGQTEVVRELVTNGANVNAQSQNGFTPLYMA 148
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Match: ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:NCBI gene;Acc:779804]) HSP 1 Score: 548.125 bits (1411), Expect = 0.000e+0 Identity = 321/774 (41.47%), Postives = 456/774 (58.91%), Query Frame = 3
Query: 135 NKMPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHAS-CCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGK----NNEP-WALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXX-XIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQK-SGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIE----DISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTER 2420
KM A+ RLE LQI KVLQC +D +Q++KL+ G++ LIN EP NG L +A + N++D FLL LGA P++ D G + M A ++GH E LAKAGAD+ + + GK +L+YC+S T+RH CL+ AL Y D+NN + +G +LF ACE ++ + +CL LL GA+PN TG+T LM A G+ + L+ G D N D AVH+AAK G F+ L L A+ A + N +H+AA+G S CC+FLGQRGCNP KN + +AK+ G K +KE+ KV R F K K N P WAL L+DW + + E+ +LLD + G V K+EF L+ AP+ E + IL + +K + GT +FL G KY+ K +L+S++ KKKK KK GK + +P+ IC MP I R DGGPP IP Q TDLNRF ++PP N + DD WYI +P++ + +++ A K GD++S++ A + G +D +D FYKT LMSA GNL++ +L+ GADVNA DNF WTPLHHA H+ I +LL+ +GA +DA A NG+TPL RAIES N L+ GAK+Q++N KG T LD+A +AD R+I++I+AK+D+LP K+KKG+ G+ +T P+ P E Q + + ++ + ++ +S E DI+F P+ + + P ++ R RRQ F +++DF D FQ F KNLTE+
Sbjct: 3 QKMAEAEERLETLQIYKVLQCVLNQDKEQLEKLISLGIKDLINSTEPRNGDGALHLAAAANNVDMCVFLLSLGAQPNIQDLNGCTPAMKATEHGHDLVLEVLAKAGADMSIVNNKGKGILFYCISATKRHLRCLQIALDYGADVNNCTTEGMPILFGACEQAQDCKAMCLKLLDKGANPNSSNPKTGRTALMEAAREGALEVVRSILEKGGDVNAIDNERNHAVHFAAKGGFFEVLKVLSAYKADMGIIAMDGNTALHHAASGGFSECCRFLGQRGCNPLWKNVKTMTPKDLAKEGGFKAAVKEIGKVTRLFKKYSKPTAQNPNPLWALTLHDWASVHEAVLREKFQLLD-KGDGTVGKEEFASALLEAGAPITPEQLQNILGRHEKGRTGTLSVEEFLKGSKYLQKAFLLSSYGLKKKKGKKKGKKGKKGKLSLPMPICTMPSDFISRRDDGGPPKFLIPTFQNVTDLNRFDWDHPPQNPLTDDTGWYIDEPEKVYTHISVATKTGDMESLRKAFEDGVPLDVKDMFYKTPLMSACASGNLNVVQYLLEQGADVNATDNFLWTPLHHACHASQDAIADLLLKHGAKIDALAFNGSTPLMRAIESGSLNCAHLLINSGAKVQIQNKKGQTVLDVAKAYADYRLIDMIQAKLDSLPKPKEKKGKTKGNMEGKAKGPKTQTPGPSDPAHIKQELIQTKLAVPSKEKKSGIIHLNSMITAGETKRVDITFVPKSVWIAEPTTAERMKKREVRRQIFSYDVDF-DNFQMPFTKNLTEK 774
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Match: ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:NCBI gene;Acc:779804]) HSP 1 Score: 533.102 bits (1372), Expect = 1.727e-177 Identity = 313/769 (40.70%), Postives = 441/769 (57.35%), Query Frame = 3
Query: 135 NKMPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHAS-CCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGK----NNEP-WALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXX-XIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTER 2420
KM A+ RLE LQI KVLQC +D +Q++KL+ G++ LIN EP NG L +A + N++D FLL LGA P++ D G + M A ++GH E LAKAGAD+ + + GK +L+YC+S T+RH CL+ AL Y D+NN + +G +LF ACE ++ + +CL LL GA+PN TG+T LM A G+ + L+ G D N D AVH+AAK G F+ L L A+ A + N +H+AA+G S CC+FLGQRGCNP KN + +AK+ G K +KE+ KV R F K K N P WAL L+DW + + E+ +LLD + G V K+EF L+ AP+ E + IL + +K + GT +FL G KY+ K +L+S++ KKKK KK GK + +P+ IC MP I R DGGPP IP Q TDLNRF ++PP N + DD WYI +P++ + +++ A K GD++S++ A + G +D +D FYKT LMSA GNL++ +L+ GADVNA DNF WTPLHHA H+ I +LL+ +GA +DA A NG+TPL RAIES N L+ GAK+Q++N KG T LD+A +AD R+I++I+AK+D+L P +K + + +KG +T +P S P I+ + + + P ++ R RRQ F +++DF D FQ F KNLTE+
Sbjct: 3 QKMAEAEERLETLQIYKVLQCVLNQDKEQLEKLISLGIKDLINSTEPRNGDGALHLAAAANNVDMCVFLLSLGAQPNIQDLNGCTPAMKATEHGHDLVLEVLAKAGADMSIVNNKGKGILFYCISATKRHLRCLQIALDYGADVNNCTTEGMPILFGACEQAQDCKAMCLKLLDKGANPNSSNPKTGRTALMEAAREGALEVVRSILEKGGDVNAIDNERNHAVHFAAKGGFFEVLKVLSAYKADMGIIAMDGNTALHHAASGGFSECCRFLGQRGCNPLWKNVKTMTPKDLAKEGGFKAAVKEIGKVTRLFKKYSKPTAQNPNPLWALTLHDWASVHEAVLREKFQLLD-KGDGTVGKEEFASALLEAGAPITPEQLQNILGRHEKGRTGTLSVEEFLKGSKYLQKAFLLSSYGLKKKKGKKKGKKGKKGKLSLPMPICTMPSDFISRRDDGGPPKFLIPTFQNVTDLNRFDWDHPPQNPLTDDTGWYIDEPEKVYTHISVATKTGDMESLRKAFEDGVPLDVKDMFYKTPLMSACASGNLNVVQYLLEQGADVNATDNFLWTPLHHACHASQDAIADLLLKHGAKIDALAFNGSTPLMRAIESGSLNCAHLLINSGAKVQIQNKKGQTVLDVAKAYADYRLIDMIQAKLDSL-PKPKEKKGKTKGNMEGKAKGPKTQTPG----------------------------PSDPAHIK------QEVWIAEPTTAERMKKREVRRQIFSYDVDF-DNFQMPFTKNLTEK 734
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080]) HSP 1 Score: 112.464 bits (280), Expect = 1.606e-24 Identity = 135/604 (22.35%), Postives = 244/604 (40.40%), Query Frame = 3
Query: 216 DQIKKLVDNGVEHLINYN-EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLT-GKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
D +++LV++G N N + G T L +A EN L +KFLL+ GA+ ++ +G + + +A Q GH +NV+ Y +S ++ V L + + ++ +LL++ + +++ K TG TPL A + ++ L G + N ++G +A+H A++ GN + L GAQ D + P+H A GH + L G + K NG +A DC++ +++ + D T++++T + + F++LL++ A ++ EK P + D ADFL K VN A + + G ++ +E P+ P G +++ T + D+ + + + F ++ AAK+G + +L L++ ++ + T L A ++ +L++ L+N GA + +TPLH A +D L+ GA +A++L G TPL A + ++V LL K A + + N LTPL LA
Sbjct: 83 DVVRELVNHGA----NVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGH---------------------ENVVAYLIS----------YGMKGKVRLPALHIAAR----------NDDTRTAAVLLQNDPNADVLSK-TGFTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHID--------------DITLDHLTPL-HVAAHCAIYYYYFFALTSFMELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNA----RAKDDQTPLHCAARSGHYEMVRLLLENGAHPDP----PTTAGHTPLHLTTRGGHTQTAEL---------LLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLA 608 HSP 2 Score: 76.2554 bits (186), Expect = 2.325e-13 Identity = 50/160 (31.25%), Postives = 80/160 (50.00%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA+ G D + L L K V ++ T L A+ G+L++ L+++ A V A+ + PLH A H G I +V+ L+ + A V+A G TPL +A + ++V LLK GA + G+TPL +A V +++ D P ++ KG
Sbjct: 575 AAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLGYISVTDVLSLVTDG-PHIQVSKG 733 HSP 3 Score: 72.7886 bits (177), Expect = 2.865e-12 Identity = 46/143 (32.17%), Postives = 76/143 (53.15%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
F ++ AA + +L+ +L L +G V+ + +AL A+ GN+ M L++ GA ++A TPLH A +G + I E+L+++GA + AK NG +P+ A + + V LL+ A I LTPL +A + A
Sbjct: 198 FTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVAAHCA 340 HSP 4 Score: 70.4774 bits (171), Expect = 1.232e-11 Identity = 47/158 (29.75%), Postives = 75/158 (47.47%), Query Frame = 3
Query: 1611 MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDAL 2075
++ A H L+ ++L L KG R T L A ++D L+ +GA NA+ TPLH AA G D+V LL++ A V + TPL A + N+ E L+ A + E G PL +A ++ + +V+ + +A V+A+
Sbjct: 506 LHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAV 663 HSP 5 Score: 70.0922 bits (170), Expect = 1.589e-11 Identity = 44/142 (30.99%), Postives = 74/142 (52.11%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
AA+ G+LD L+ G ++T ++ AL ++ G++ M L++ + T LH AA +G D+V L+N+GA V++++ G TPL+ A + + VV+FLL+ GA + G TPL +A V+
Sbjct: 10 AARAGNLDKALDHLRNGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVV 151 HSP 6 Score: 69.707 bits (169), Expect = 2.212e-11 Identity = 49/151 (32.45%), Postives = 67/151 (44.37%), Query Frame = 3
Query: 1647 IKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
++L LK G +D +T L AA + D+ LI A VNA+ TPLH AA SG ++V LL+ NGA D G TPL E LL A KG TPL +A + ++ ++ + +A P K G
Sbjct: 353 MELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLER-EAHPNSAGKTG 502 HSP 7 Score: 67.781 bits (164), Expect = 8.961e-11 Identity = 49/172 (28.49%), Postives = 84/172 (48.84%), Query Frame = 3
Query: 1590 PDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRF--------NVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
P ++ A++ G++ ++L L +G ++D + T L A G++ + L+++GA + AK +P+H A+ +D V LL+ A +D L+ TPL A + + + +E LLK GA I K TPL +A A + V + + KAKV+A
Sbjct: 227 PQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVAAHCAIYYYYFFALTSFMELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNA 398 HSP 8 Score: 67.3958 bits (163), Expect = 1.117e-10 Identity = 46/176 (26.14%), Postives = 82/176 (46.59%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--------KAKVDALPPVKDKKGRG 2105
+ ++ A K +D+ + L+ G + + T L AA G+ DM L++ A+V+ + TPLH A+ G ++I E+L+++ A V A+ G PL A VV+FLL+ A + G TPL A + ++ ++ +A ++ + P+ K G
Sbjct: 536 YTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 711 HSP 9 Score: 67.3958 bits (163), Expect = 1.290e-10 Identity = 54/183 (29.51%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSG 827
NG T L +A + +DT + LL GA + +G + + +AAQ GH L A++ L + + L+ ++ E H E + ++ + ++ G L AC G N ++ LL+H A+ N + K G TPL A G T I + LK G PN A +G T + A + G
Sbjct: 534 NGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLH--LASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYG--NIKVVKFLLQHQANVNAVTK-LGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 711 HSP 10 Score: 67.0106 bits (162), Expect = 1.478e-10 Identity = 44/145 (30.34%), Postives = 75/145 (51.72%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
++K G + + L K ++T + TAL AA G D+ L+N+GA+VN++ +TPL+ AA + +V+ L+ NGA + +G TPL A++ NVV +L+ G K ++ L L +A D+R ++
Sbjct: 43 SSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVR----LPALHIAARNDDTRTAAVL 183 HSP 11 Score: 66.2402 bits (160), Expect = 2.767e-10 Identity = 39/120 (32.50%), Postives = 60/120 (50.00%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK 2063
T L AA YG + + L+ A N+ TPLH A + ++IV LL+N GA A NG TPL A++ + LL+ GA ++ +G+TPL LA ++ ++ +K
Sbjct: 471 TPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSK 590 HSP 12 Score: 60.077 bits (144), Expect = 2.085e-8 Identity = 68/260 (26.15%), Postives = 102/260 (39.23%), Query Frame = 3
Query: 285 KTCLSIATSENDLDTIKFLLDLGAHPDVVDF-------------EGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
K+ SI ++T + AH DV DF + ++ + AA+ GH L + GA G L+ ++ H + E L +++K G T L A + GK +I +LL+ A PN K TG TPL A +I L G P+ R+G T +H A K + + AL FGA + P+H AA GH L + N + N + +A +G
Sbjct: 358 KSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLH--LTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKI--QIAELLLEREAHPNSAGK-TGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEG 612 HSP 13 Score: 58.151 bits (139), Expect = 6.825e-8 Identity = 57/201 (28.36%), Postives = 83/201 (41.29%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYG-------------------------------ADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
F + AA+ L +K L+ G + T D F T L A G+ ++ +LI+YG ADV +K F TPLH AAH +++ +LL+N GA V+ NG + L A +V LL +GA+I LTPL A R+ I+ +D P++ K G
Sbjct: 103 FTPLYMAAQENHLPVVKFLLENGANQNLATEDGF--TPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLSKTGF--TPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEIL---LDHGAPIQAKTKNG 296 HSP 14 Score: 53.5286 bits (127), Expect = 1.936e-6 Identity = 31/107 (28.97%), Postives = 54/107 (50.47%), Query Frame = 3
Query: 1698 YKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+ T+ + AA GNLD + + G D+N + LH ++ G + +V L++ V++ G T L A + + +VV L+ GA + ++ KG TPL +A
Sbjct: 3 FTTSFLRAARAGNLDKALDHLRNGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMA 109 HSP 15 Score: 53.5286 bits (127), Expect = 2.217e-6 Identity = 73/308 (23.70%), Postives = 112/308 (36.36%), Query Frame = 3
Query: 213 YDQIKKLVDNGVEHLINYNEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYG--------------------------HVASFES-------LAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
Y+ ++ L++NG PD G T L + T T + LLD A + +G + + +AA+YG HVA + + L GA NG L+ V +R + L++ N S G T L A ++G + ++ +LL A+ ++ K++ TPL A G +I + R G +H A GN K + L A + P+H AA GH L + G P + NG IAK G
Sbjct: 416 YEMVRLLLENGAH-------PDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVK--QRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEG--HGDMVTLLLSKQANVHLGNKSS-LTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 711
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Match: ANK1 (ankyrin 1 [Source:NCBI gene;Acc:613080]) HSP 1 Score: 112.464 bits (280), Expect = 1.932e-24 Identity = 134/603 (22.22%), Postives = 245/603 (40.63%), Query Frame = 3
Query: 216 DQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLT-GKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
D +++LV++G +N ++ G T L +A EN L +KFLL+ GA+ ++ +G + + +A Q GH +NV+ Y +S ++ V L + + ++ +LL++ + +++ K TG TPL A + ++ L G + N ++G +A+H A++ GN + L GAQ D + P+H A GH + L G + K NG +A DC++ +++ + D T++++T + + F++LL++ A ++ EK P + D ADFL K VN A + + G ++ +E P+ P G +++ T + D+ + + + F ++ AAK+G + +L L++ ++ + T L A ++ +L++ L+N GA + +TPLH A +D L+ GA +A++L G TPL A + ++V LL K A + + N LTPL LA
Sbjct: 125 DVVRELVNHGAN--VN-SQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGH---------------------ENVVAYLIS----------YGMKGKVRLPALHIAAR----------NDDTRTAAVLLQNDPNADVLSK-TGFTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHID--------------DITLDHLTPL-HVAAHCAIYYYYFFALTSFMELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNA----RAKDDQTPLHCAARSGHYEMVRLLLENGAHPDP----PTTAGHTPLHLTTRGGHTQTAEL---------LLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLA 650 HSP 2 Score: 76.2554 bits (186), Expect = 2.198e-13 Identity = 50/160 (31.25%), Postives = 80/160 (50.00%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA+ G D + L L K V ++ T L A+ G+L++ L+++ A V A+ + PLH A H G I +V+ L+ + A V+A G TPL +A + ++V LLK GA + G+TPL +A V +++ D P ++ KG
Sbjct: 617 AAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLGYISVTDVLSLVTDG-PHIQVSKG 775 HSP 3 Score: 72.7886 bits (177), Expect = 2.708e-12 Identity = 46/143 (32.17%), Postives = 76/143 (53.15%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWA 2030
F ++ AA + +L+ +L L +G V+ + +AL A+ GN+ M L++ GA ++A TPLH A +G + I E+L+++GA + AK NG +P+ A + + V LL+ A I LTPL +A + A
Sbjct: 240 FTPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVAAHCA 382 HSP 4 Score: 70.4774 bits (171), Expect = 1.194e-11 Identity = 47/158 (29.75%), Postives = 75/158 (47.47%), Query Frame = 3
Query: 1611 MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDAL 2075
++ A H L+ ++L L KG R T L A ++D L+ +GA NA+ TPLH AA G D+V LL++ A V + TPL A + N+ E L+ A + E G PL +A ++ + +V+ + +A V+A+
Sbjct: 548 LHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAV 705 HSP 5 Score: 70.0922 bits (170), Expect = 1.554e-11 Identity = 44/142 (30.99%), Postives = 74/142 (52.11%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
AA+ G+LD L+ G ++T ++ AL ++ G++ M L++ + T LH AA +G D+V L+N+GA V++++ G TPL+ A + + VV+FLL+ GA + G TPL +A V+
Sbjct: 52 AARAGNLDKALDHLRNGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVV 193 HSP 6 Score: 69.707 bits (169), Expect = 2.334e-11 Identity = 49/151 (32.45%), Postives = 67/151 (44.37%), Query Frame = 3
Query: 1647 IKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
++L LK G +D +T L AA + D+ LI A VNA+ TPLH AA SG ++V LL+ NGA D G TPL E LL A KG TPL +A + ++ ++ + +A P K G
Sbjct: 395 MELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLER-EAHPNSAGKTG 544 HSP 7 Score: 67.781 bits (164), Expect = 8.613e-11 Identity = 49/172 (28.49%), Postives = 84/172 (48.84%), Query Frame = 3
Query: 1590 PDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRF--------NVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
P ++ A++ G++ ++L L +G ++D + T L A G++ + L+++GA + AK +P+H A+ +D V LL+ A +D L+ TPL A + + + +E LLK GA I K TPL +A A + V + + KAKV+A
Sbjct: 269 PQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEILLDHGAPIQAKTKNGLSPIHMASQGDHLDCVRLLLQYQAHIDDITLDHLTPLHVAAHCAIYYYYFFALTSFMELLLKSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNA 440 HSP 8 Score: 67.3958 bits (163), Expect = 1.056e-10 Identity = 46/176 (26.14%), Postives = 82/176 (46.59%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII--------KAKVDALPPVKDKKGRG 2105
+ ++ A K +D+ + L+ G + + T L AA G+ DM L++ A+V+ + TPLH A+ G ++I E+L+++ A V A+ G PL A VV+FLL+ A + G TPL A + ++ ++ +A ++ + P+ K G
Sbjct: 578 YTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 753 HSP 9 Score: 67.0106 bits (162), Expect = 1.350e-10 Identity = 54/183 (29.51%), Postives = 85/183 (46.45%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSG 827
NG T L +A + +DT + LL GA + +G + + +AAQ GH L A++ L + + L+ ++ E H E + ++ + ++ G L AC G N ++ LL+H A+ N + K G TPL A G T I + LK G PN A +G T + A + G
Sbjct: 576 NGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLH--LASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYG--NIKVVKFLLQHQANVNAVTK-LGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 753 HSP 10 Score: 67.0106 bits (162), Expect = 1.457e-10 Identity = 44/145 (30.34%), Postives = 75/145 (51.72%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
++K G + + L K ++T + TAL AA G D+ L+N+GA+VN++ +TPL+ AA + +V+ L+ NGA + +G TPL A++ NVV +L+ G K ++ L L +A D+R ++
Sbjct: 85 SSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMAAQENHLPVVKFLLENGANQNLATEDGFTPLAVALQQGHENVVAYLISYGMKGKVR----LPALHIAARNDDTRTAAVL 225 HSP 11 Score: 66.2402 bits (160), Expect = 2.751e-10 Identity = 39/120 (32.50%), Postives = 60/120 (50.00%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK 2063
T L AA YG + + L+ A N+ TPLH A + ++IV LL+N GA A NG TPL A++ + LL+ GA ++ +G+TPL LA ++ ++ +K
Sbjct: 513 TPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSK 632 HSP 12 Score: 59.6918 bits (143), Expect = 2.561e-8 Identity = 68/260 (26.15%), Postives = 102/260 (39.23%), Query Frame = 3
Query: 285 KTCLSIATSENDLDTIKFLLDLGAHPDVVDF-------------EGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
K+ SI ++T + AH DV DF + ++ + AA+ GH L + GA G L+ ++ H + E L +++K G T L A + GK +I +LL+ A PN K TG TPL A +I L G P+ R+G T +H A K + + AL FGA + P+H AA GH L + N + N + +A +G
Sbjct: 400 KSGASIDAVTEKVETPLHMAARAAHTDVADFLIQNKAKVNARAKDDQTPLHCAARSGHYEMVRLLLENGAHPDPPTTAGHTPLH--LTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKI--QIAELLLEREAHPNSAGK-TGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVKQRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEGHGDMVTLLLSKQANVHLGNKSSLTPLHLASQEG 654 HSP 13 Score: 58.5362 bits (140), Expect = 6.613e-8 Identity = 57/201 (28.36%), Postives = 83/201 (41.29%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKG--YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYG-------------------------------ADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
F + AA+ L +K L+ G + T D F T L A G+ ++ +LI+YG ADV +K F TPLH AAH +++ +LL+N GA V+ NG + L A +V LL +GA+I LTPL A R+ I+ +D P++ K G
Sbjct: 145 FTPLYMAAQENHLPVVKFLLENGANQNLATEDGF--TPLAVALQQGHENVVAYLISYGMKGKVRLPALHIAARNDDTRTAAVLLQNDPNADVLSKTGF--TPLHIAAHYENLNVAQLLLNRGANVNFTPQNGISALHIASRRGNVIMVRLLLDRGAQIDACTKDELTPLHCAVRNGHVRISEIL---LDHGAPIQAKTKNG 338 HSP 14 Score: 53.1434 bits (126), Expect = 2.745e-6 Identity = 73/308 (23.70%), Postives = 112/308 (36.36%), Query Frame = 3
Query: 213 YDQIKKLVDNGVEHLINYNEPD----NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYG--------------------------HVASFES-------LAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
Y+ ++ L++NG PD G T L + T T + LLD A + +G + + +AA+YG HVA + + L GA NG L+ V +R + L++ N S G T L A ++G + ++ +LL A+ ++ K++ TPL A G +I + R G +H A GN K + L A + P+H AA GH L + G P + NG IAK G
Sbjct: 458 YEMVRLLLENGAH-------PDPPTTAGHTPLHLTTRGGHTQTAELLLDNQAAHTSMTKKGFTPLHVAAKYGKIQIAELLLEREAHPNSAGKTGLTPLHVAVYHNHLNIVRLLLNKGASPHCTARNGYTPLHMAVK--QRSVDTARALLQFGATCNAQSLQGVTPLHLAAQEG--HGDMVTLLLSKQANVHLGNKSS-LTPLHLASQEGHLNIAEVLVSHDASVAAETRMGFAPLHVACHYGNIKVVKFLLQHQANVNAVTKLGFTPLHQAAQQGHTDIVTLLLKNGACPNQASMNGITPLAIAKRLG 753 HSP 15 Score: 52.373 bits (124), Expect = 4.965e-6 Identity = 31/105 (29.52%), Postives = 53/105 (50.48%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T+ + AA GNLD + + G D+N + LH ++ G + +V L++ V++ G T L A + + +VV L+ GA + ++ KG TPL +A
Sbjct: 47 TSFLRAARAGNLDKALDHLRNGVDINTCNQNGLNALHLSSKEGHVKMVTELLHKDIVLETTTKKGNTALHIAALAGQEDVVRELVNHGANVNSQSQKGFTPLYMA 151
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Match: foxj3 (forkhead box J3 [Source:Xenbase;Acc:XB-GENE-481185]) HSP 1 Score: 110.153 bits (274), Expect = 8.956e-24 Identity = 159/680 (23.38%), Postives = 266/680 (39.12%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE------------------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMK------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMND-------AAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVK 2087
R++ + D ++++L++ G N N D T L A D ++ LL GA+ D G + A +GH L GAD D N + S + C+ L++ D + + DGK+ L A K NEE + LL H +D TPL A I L+ G D + D+ G +H A G+F+ L GA + D Q P+H AA+ C L G +P + N +G+ A +A K+ + +++ R + K + AL + ++ E + L +K+ +LL+R A +NE+ + + P + D + L K+ K M+A + + ++ + R GG + +D + S + ++ ++ I + + T V +D A+K GDLD++K L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL + D+ + ++++ L K
Sbjct: 161 FRELFEACRNGDVSRVRRLLEPG-----NVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQTGANVHARDDGGLIPLHNACSFGHAEVVTLLLCQGADPNARD-NWNYTPLHEASIKGKIDVCI-VLLQHGADPSIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHFEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKERLSYEFKGHSLLQAARE-ADMAKVKKTLALEIINFKQPQSHETALHCAVASLHP----KRKQITELLLRKGASVNEKNKDFMTPLHVAAERAHNDVVEVL--HKHGAK---MNALD------------------------TLGQTALHRAALGGHLQTCRLLLSFGSDASIVSLQGFTAAQMGNEAVQQILNVESTPVRTSDVDYRLLEASKAGDLDTVK-QLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLRGDAALLDAAK 791 HSP 2 Score: 101.293 bits (251), Expect = 3.915e-21 Identity = 164/670 (24.48%), Postives = 253/670 (37.76%), Query Frame = 3
Query: 294 LSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNII-----------------------------------------------------QKATGKTPLMAACAS---GSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNN----EPWALGLYDWTVENMTEIVEELKLLDLEN--------SGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLT---GKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSI-KLALKKGYKV-DTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
L A S N+ + L L + D + + +AA Y V + L + GAD+ D G L+ S H E E L++ +N + T L A K E+C +LL HGADP ++ Q + +T L A AS I L+ G N ++ T +H AA+ + + L GA+ + D +H AA GH C+ L G + + + G A + + +++++ VE + + + E G D TV+ + + + DLE + N+ V+ L+ A ++ + + ++P + G ++ A+ L V L+ + K K EIC + H P T NR N P + ++D I D R + DAAK G L + KL ++ DT+ R T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N + TPLDLA AD +I +DA+PP
Sbjct: 318 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACS--YGHFEVTELLLKHGACVNAMDLWQFTPLHEAAS--KNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELKERLSYEFKGHSLLQAAREADMAKVKKTLALEIINFKQPQSHETALHCAVASLHPKRKQITELLLRKGASVNEKNKDFMTPLHVAAERAHNDVVEVLHKHGAKMNALDTLGQTALHRAALGGHLQTCRLLLSFGSDASIVSLQGFTAAQMGNE-----AVQQILNVESTPVRTSDVDYRLLEASKAGDLD-TVKQLCS-SQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGK-------------YEICKLLLKHGADP----------------TKKNR--DGNTPLDLVKDG-DTDIQDLLRGDAALLDAAKKGCLARVQKLCTQENINCRDTQGR-NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQTPLDLA--TAD----DIRALLIDAMPP 937 HSP 3 Score: 51.6026 bits (122), Expect = 6.576e-6 Identity = 71/293 (24.23%), Postives = 112/293 (38.23%), Query Frame = 3
Query: 183 KVLQCTYEKDYDQIKKLVDNGVEHLINYNEPD---NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKEN---------------EEICLI-LLKHGADPNIIQKAT---GKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
++L+ + D D +K+L + N N D T L A N + +++LL GA D G + A YGH E L + GA + + DL L+ + + E + L++ D ++DG T L +DG + ++ CL + K NI + T TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN +
Sbjct: 632 RLLEASKAGDLDTVKQLCSSQ-----NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPL-DLVKDGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTQENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQESQ 916
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Match: Ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:MGI Symbol;Acc:MGI:2441685]) HSP 1 Score: 537.339 bits (1383), Expect = 8.460e-179 Identity = 308/772 (39.90%), Postives = 439/772 (56.87%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDK---KGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I +TG+T LM + G I L+ G + N D A H+AAK G F L L A+ + N P+H+AA G A CCK++ QRGC+ K KN + R +AKD G K KE+ + ER+ KL K N WAL L+DW++E+ T + K +D G+V+K +FV L + E + +K++ G + +F G KY++K Y++ +F KKKK+ G K + K +P+ IC +PE+ R DGGPP I Q +D +RF+ ++PP + I+DD WYI DP R F N++ K GDL S+K A++ G VD +D YKT LM A GN+D+ LI GA+VNA DNF WTPLH A H+G DIVELL+ GA +DA ++N +TPL RAIES R + V++LL GAK Q+EN KG +D+A +AD R+I++IK K+D LP D KG+ + + + + + P ++ ++ N+L++ + DI+F P+ + L++ R RR+RF +E+DF D F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVD-RGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKK--VDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFED-FMMPFQKNITEKAQA 768
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Match: Ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:MGI Symbol;Acc:MGI:2441685]) HSP 1 Score: 537.339 bits (1383), Expect = 8.460e-179 Identity = 308/772 (39.90%), Postives = 439/772 (56.87%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDK---KGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I +TG+T LM + G I L+ G + N D A H+AAK G F L L A+ + N P+H+AA G A CCK++ QRGC+ K KN + R +AKD G K KE+ + ER+ KL K N WAL L+DW++E+ T + K +D G+V+K +FV L + E + +K++ G + +F G KY++K Y++ +F KKKK+ G K + K +P+ IC +PE+ R DGGPP I Q +D +RF+ ++PP + I+DD WYI DP R F N++ K GDL S+K A++ G VD +D YKT LM A GN+D+ LI GA+VNA DNF WTPLH A H+G DIVELL+ GA +DA ++N +TPL RAIES R + V++LL GAK Q+EN KG +D+A +AD R+I++IK K+D LP D KG+ + + + + + P ++ ++ N+L++ + DI+F P+ + L++ R RR+RF +E+DF D F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVD-RGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKK--VDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFED-FMMPFQKNITEKAQA 768
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Match: Ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:MGI Symbol;Acc:MGI:2441685]) HSP 1 Score: 537.339 bits (1383), Expect = 8.460e-179 Identity = 308/772 (39.90%), Postives = 439/772 (56.87%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDK---KGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I +TG+T LM + G I L+ G + N D A H+AAK G F L L A+ + N P+H+AA G A CCK++ QRGC+ K KN + R +AKD G K KE+ + ER+ KL K N WAL L+DW++E+ T + K +D G+V+K +FV L + E + +K++ G + +F G KY++K Y++ +F KKKK+ G K + K +P+ IC +PE+ R DGGPP I Q +D +RF+ ++PP + I+DD WYI DP R F N++ K GDL S+K A++ G VD +D YKT LM A GN+D+ LI GA+VNA DNF WTPLH A H+G DIVELL+ GA +DA ++N +TPL RAIES R + V++LL GAK Q+EN KG +D+A +AD R+I++IK K+D LP D KG+ + + + + + P ++ ++ N+L++ + DI+F P+ + L++ R RR+RF +E+DF D F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVD-RGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKK--VDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFED-FMMPFQKNITEKAQA 768
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Match: Ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:MGI Symbol;Acc:MGI:2441685]) HSP 1 Score: 298.516 bits (763), Expect = 5.530e-92 Identity = 164/412 (39.81%), Postives = 231/412 (56.07%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAF 1358
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I +TG+T LM + G I L+ G + N D A H+AAK G F L L A+ + N P+H+AA G A CCK++ QRGC+ K KN + R +AKD G K KE+ + ER+ KL K N WAL L+DW++E+ T + K +D G+V+K +FV L + E + +K++ G + +F G KY++K Y++ +F
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVD-RGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSF 411 HSP 2 Score: 50.8322 bits (120), Expect = 5.528e-6 Identity = 29/102 (28.43%), Postives = 52/102 (50.98%), Query Frame = 3
Query: 1701 KTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTP 2006
+TALM ++ G L++ ++ G +VNA DN H AA G DI++LL + ++G TPL A + +++ ++G ++ +N + TP
Sbjct: 186 RTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTP 287
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Match: Ankef1 (ankyrin repeat and EF-hand domain containing 1 [Source:MGI Symbol;Acc:MGI:2441685]) HSP 1 Score: 171.014 bits (432), Expect = 2.329e-48 Identity = 86/180 (47.78%), Postives = 114/180 (63.33%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNII 680
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAI 180
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9NU02|ANKE1_HUMAN (Ankyrin repeat and EF-hand domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKEF1 PE=2 SV=2) HSP 1 Score: 541.576 bits (1394), Expect = 1.584e-179 Identity = 320/776 (41.24%), Postives = 450/776 (57.99%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLG----KNNEP-WALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALP-PVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALK----RANNLLS--YSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI KVLQC KD QI+KL G LINY EP NG + L +A+ ND+D + FLLDLGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN + +GK + ACED + +++CL L+ GA+PN I +TG+T LM A G I L+ G + N D A H+AAK G F L L A+ + N P+HYAA G A CCK++ QRGC+ K KN + + R +AK+ G K KE+ + ER KL KN P WAL L+DW+VE + E +LD G ++K +FV +L + + E I +K + G + +F G +Y+NK +++ ++ KKK+K G KGK K +P+ ICV+PE R DGGPP I + TD +RF+ ++PP + I+DD WYI D ++ F N+N K GDL S+K A + G VD +D +YKT LM+A GN+D+ L+ GA+VNA DNF WTPLH A H+G DIVELL+ +GA++DA ++N +TPL RAIES R + V++LL GAK Q+EN KG + +D+A +AD R+I++IK K+D LP P +++K +G + ++G + + P S + K N+L++ Y+ K DI+F PR + L++ R RR+RF E+DF D+F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLD-RGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKG-KTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKV----DITFIPRRIWSPEATTAELIRKRELRRERFTHEVDF-DDFMMPFQKNITEKARA 769
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9D2J7|ANKE1_MOUSE (Ankyrin repeat and EF-hand domain-containing protein 1 OS=Mus musculus OX=10090 GN=Ankef1 PE=2 SV=1) HSP 1 Score: 537.339 bits (1383), Expect = 5.918e-178 Identity = 308/772 (39.90%), Postives = 439/772 (56.87%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDK---KGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKA 2429
M +A RLE LQI +VLQC KD QI+KL G LIN+ EP +G + L +A+ ND D + FLL LGAHPDV D G + M AA+ GH S E LAKA AD+ + D GK VL+YC+ PT+RH C AL + D+NN++ +GK V ACE+ + +++CL L+ GA+PN I +TG+T LM + G I L+ G + N D A H+AAK G F L L A+ + N P+H+AA G A CCK++ QRGC+ K KN + R +AKD G K KE+ + ER+ KL K N WAL L+DW++E+ T + K +D G+V+K +FV L + E + +K++ G + +F G KY++K Y++ +F KKKK+ G K + K +P+ IC +PE+ R DGGPP I Q +D +RF+ ++PP + I+DD WYI DP R F N++ K GDL S+K A++ G VD +D YKT LM A GN+D+ LI GA+VNA DNF WTPLH A H+G DIVELL+ GA +DA ++N +TPL RAIES R + V++LL GAK Q+EN KG +D+A +AD R+I++IK K+D LP D KG+ + + + + + P ++ ++ N+L++ + DI+F P+ + L++ R RR+RF +E+DF D F F KN+TE+ +A
Sbjct: 1 MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVD-RGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKK--VDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFED-FMMPFQKNITEKAQA 768
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q6PFX9|TNKS1_MOUSE (Poly [ADP-ribose] polymerase tankyrase-1 OS=Mus musculus OX=10090 GN=Tnks PE=1 SV=1) HSP 1 Score: 107.457 bits (267), Expect = 2.547e-22 Identity = 154/653 (23.58%), Postives = 256/653 (39.20%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE------------------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMK------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRP----IDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDL 2015
+R++L+ D ++K+LVD N N D + L A D ++ LL +GA+ D G + A +GH L GAD D N + + + C+ L++ D N + DGK+ L A K NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N +G+ A +A ++ + +++ R L K + AL + ++ E + L +K+ +LL+R A +NE+ + + P + D + L K+ K+ + + + ++ C + S+ P + G + + + + + SE+ P D D + +A+K GDL+++K L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL
Sbjct: 176 LRELLEACRNGDVSRVKRLVDAA-----NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD-NWNYTPLHEAAIKGKIDVCI-VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAARE-ADLAKVKKTLALEIINFKQPQSHETALHCAVASLHP----KRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDSLGQTALHRAALAGH--------LQTCRLLLSYGSDPSIISLQG-----FTAAQMGNEAVQQILSESTP---------MRTSDVDYRLL---EASKAGDLETVK-QLCSPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 782 HSP 2 Score: 85.8853 bits (211), Expect = 1.137e-15 Identity = 65/169 (38.46%), Postives = 87/169 (51.48%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
I D R + DAAK G L ++ L ++ RD + T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G TPLDLA AD +I +DA+PP
Sbjct: 790 IQDLLRGDAALLDAAKKGCLARVQ-KLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA--TAD----DIRALLIDAMPP 951 HSP 3 Score: 68.1662 bits (165), Expect = 3.427e-10 Identity = 40/105 (38.10%), Postives = 56/105 (53.33%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T L AA Y + + L+ +GADV+AKD PLH+A G ++ ELL+ +GA V+A L TPL A +R V LL GA + N G + +D+A
Sbjct: 364 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 468 HSP 4 Score: 65.855 bits (159), Expect = 1.607e-9 Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ +D + + L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G + LDLA
Sbjct: 181 EACRNGDVSRVK-RLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 315 HSP 5 Score: 62.3882 bits (150), Expect = 2.177e-8 Identity = 47/146 (32.19%), Postives = 76/146 (52.05%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGA-----VVDAK-ALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSR 2039
AA G D ++ L+ G V RD L +A +G+ ++ L+ GAD NA+DN+++TPLH AA G ID+ +L+ +GA D K AL+ A P +A+ + + E L + + + LTPL++ + +D R
Sbjct: 216 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 361 HSP 6 Score: 57.7658 bits (138), Expect = 5.519e-7 Identity = 75/311 (24.12%), Postives = 121/311 (38.91%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSE---NDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLIL--------------------------LKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKD 1016
+LQ E D ++KK + +IN+ +P + +T L A + + LL GA+ + + + + + +AA+ H E L K GA + D G+ L+ + H + L Y D + +S G F A + G NE + IL +K P + + TPL A S+ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + K+
Sbjct: 486 LLQAAREADLAKVKKTL---ALEIINFKQPQSHETALHCAVASLHPKRKQVAELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDSLGQTALHR--AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMG--NEAVQQILSESTPMRTSDVDYRLLEASKAGDLETVKQLCSPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 785 HSP 7 Score: 56.225 bits (134), Expect = 1.403e-6 Identity = 61/254 (24.02%), Postives = 96/254 (37.80%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEI--------------CLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
T L A N + +++LL GA D G + A YGH E L + GA + + DL L+ + + E + L++ D ++DG T L E + +++ CL ++ P I + TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN G+
Sbjct: 679 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 930 HSP 8 Score: 54.299 bits (129), Expect = 5.358e-6 Identity = 44/173 (25.43%), Postives = 75/173 (43.35%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALN----------------------GATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
V +++A +G + +L ++ G V+ D + T L AA G ++C L+ +GAD K+ TPL G DI +LL + A++DA +TPL A + V E+LL+ GA + ++ GL PL A ++ + ++
Sbjct: 711 LVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-DLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 882
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|O95271|TNKS1_HUMAN (Poly [ADP-ribose] polymerase tankyrase-1 OS=Homo sapiens OX=9606 GN=TNKS PE=1 SV=2) HSP 1 Score: 107.457 bits (267), Expect = 3.162e-22 Identity = 155/652 (23.77%), Postives = 255/652 (39.11%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE------------------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMK------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTF---VNMNDAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDL 2015
+R++L+ D ++K+LVD N N D + L A D ++ LL +GA+ D G + A +GH L GAD D N + + + C+ L++ D N + DGK+ L A K NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N +G+ A +A ++ + +++ R L K + AL + ++ E + L +K+ +LL+R A +NE+ + + P + D + L K+ K+ + + ++ C + S+ G P + L F++ + ++ S P RT + +A+K GDL+++K L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL
Sbjct: 183 LRELLEACRNGDVSRVKRLVDAA-----NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARD-NWNYTPLHEAAIKGKIDVCI-VLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPELRERLTYEFKGHSLLQAARE-ADLAKVKKTLALEIINFKQPQSHETALHCAVASLHP----KRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVL--HKHGAKMNALDTLGQTALHRAALAGH--------LQTCRLLLSY------GSDPSI--------ISLQGFTAAQMGNEAVQQILSE--STPIRTSDVDYRLLEASKAGDLETVK-QLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789 HSP 2 Score: 86.2705 bits (212), Expect = 9.778e-16 Identity = 67/169 (39.64%), Postives = 87/169 (51.48%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSI-KLALKKGYKV-DTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
I D R + DAAK G L + KL + DT+ R T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G TPLDLA AD +I +DA+PP
Sbjct: 797 IQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGR-NSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA--TAD----DIRALLIDAMPP 958 HSP 3 Score: 68.1662 bits (165), Expect = 3.317e-10 Identity = 40/105 (38.10%), Postives = 56/105 (53.33%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T L AA Y + + L+ +GADV+AKD PLH+A G ++ ELL+ +GA V+A L TPL A +R V LL GA + N G + +D+A
Sbjct: 371 TPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAVDMA 475 HSP 4 Score: 65.855 bits (159), Expect = 1.569e-9 Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ +D + + L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G + LDLA
Sbjct: 188 EACRNGDVSRVK-RLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322 HSP 5 Score: 62.3882 bits (150), Expect = 2.125e-8 Identity = 47/146 (32.19%), Postives = 76/146 (52.05%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGA-----VVDAK-ALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSR 2039
AA G D ++ L+ G V RD L +A +G+ ++ L+ GAD NA+DN+++TPLH AA G ID+ +L+ +GA D K AL+ A P +A+ + + E L + + + LTPL++ + +D R
Sbjct: 223 AAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 368 HSP 6 Score: 57.3806 bits (137), Expect = 6.658e-7 Identity = 76/311 (24.44%), Postives = 122/311 (39.23%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSE---NDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILL------------------KHGADPNIIQKATGK------------TPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKD 1016
+LQ E D ++KK + +IN+ +P + +T L A + + LL GA+ + + + + + +AA+ H E L K GA + D G+ L+ + H + L Y D + +S G F A + G NE + IL K G + Q + + TPL A S+ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + K+
Sbjct: 493 LLQAAREADLAKVKKTL---ALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHR--AALAGHLQTCRLLLSYGSDPSIISLQG----FTAAQMG--NEAVQQILSESTPIRTSDVDYRLLEASKAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKE 792 HSP 7 Score: 56.225 bits (134), Expect = 1.529e-6 Identity = 68/292 (23.29%), Postives = 111/292 (38.01%), Query Frame = 3
Query: 183 KVLQCTYEKDYDQIKKLVDNGVEHLINYNEPD---NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEI--------------CLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
++L+ + D + +K+L + N N D T L A N + +++LL GA D G + A YGH E L + GA + + DL L+ + + E + L++ D ++DG T L E + +++ CL ++ P I + TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN G+
Sbjct: 653 RLLEASKAGDLETVKQLCSSQ-----NVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQ 937 HSP 8 Score: 54.299 bits (129), Expect = 5.596e-6 Identity = 44/173 (25.43%), Postives = 75/173 (43.35%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALN----------------------GATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
V +++A +G + +L ++ G V+ D + T L AA G ++C L+ +GAD K+ TPL G DI +LL + A++DA +TPL A + V E+LL+ GA + ++ GL PL A ++ + ++
Sbjct: 718 LVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPL-DLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALL 889
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Match: sp|G5E8K5|ANK3_MOUSE (Ankyrin-3 OS=Mus musculus OX=10090 GN=Ank3 PE=1 SV=1) HSP 1 Score: 106.301 bits (264), Expect = 7.120e-22 Identity = 141/616 (22.89%), Postives = 238/616 (38.64%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELK--LLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMSAF-----EXXXXXXXXXXXXXXXXXXIPIEICVMPESH--IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPD----RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
N T L +A+ + + +K LLD GA D +G + + A+ GH E L A + NG + L+ H C++ L++NV +++V+ D T L A G + ++ +LL A PN +K L +G T +H A K + + L GA ++ PIH AA GH + L G +P N GE A +A A+ EV++ + V++ ++ + K L S + K + V L++ A N P ++G D A FL T KK L++ + + +K + P+ + ++ + +D G K Y T L+ + +N +I Y D + + +++ AA+ G +D + L L + V+ ++ T L AA +++ L+N GA V+A+ +TPLH H G I IV L+ + A V+AK NG T L +A + +++ LL+ A G T L +A V++ +K
Sbjct: 250 NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQ--GDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCG--HYKVAKVLLDKKASPN-----------------------AKAL-----------NGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMA----ARSGQAEVVR---------------------YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKN--QMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLK 799 HSP 2 Score: 81.6481 bits (200), Expect = 2.426e-14 Identity = 49/133 (36.84%), Postives = 70/133 (52.63%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
AA+ D + L L+ D + T L AAHYGN+++ L+N A V+ TPLH A+ G ++V+LL++ GA +DAK +G TPL S VVE LL + A I + GL+PL +A
Sbjct: 192 AARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMA 324 HSP 3 Score: 80.1073 bits (196), Expect = 8.808e-14 Identity = 53/160 (33.12%), Postives = 77/160 (48.12%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA G ++ + + G +T + +TAL AA G ++ +L+ GA V AK TPLH +A G DIV+ L+ GA +A +G TPL A +V FLL GA + + KG TPL +A + V +++ K A P K G
Sbjct: 423 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQK-SASPDAAGKSG 581 HSP 4 Score: 79.337 bits (194), Expect = 1.358e-13 Identity = 46/145 (31.72%), Postives = 80/145 (55.17%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ G L+ +K G V+ ++ AL A+ G++++ L+ A+V+A T LH A+ +G ++V++L+ NGA V+A++ NG TPL+ A + + VV FLL GA + G TPL +A +V++++
Sbjct: 31 AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLL 175 HSP 5 Score: 78.1814 bits (191), Expect = 3.039e-13 Identity = 52/162 (32.10%), Postives = 77/162 (47.53%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDA 2072
+ F ++ AAK+G L+ L L+K D + T L AAHY N + + L++ GA +A +TPLH AA +DI L+ GA +A G + A + ++V LL + A + + N GLTPL LA V ++ A VDA
Sbjct: 547 KGFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDA 708 HSP 6 Score: 74.7146 bits (182), Expect = 3.770e-12 Identity = 46/151 (30.46%), Postives = 76/151 (50.33%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
F ++ AA +G+++ L L + VD R T L A+ GN +M L++ GA ++AK TPLH A SG +VE+L++ A + +K NG +PL A + N V+ LL+ + + LT L +A + +V ++
Sbjct: 219 FTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 369 HSP 7 Score: 74.3294 bits (181), Expect = 4.354e-12 Identity = 66/234 (28.21%), Postives = 106/234 (45.30%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGH--VASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA 917
++ LV +G + + D+ +T L I+ D ++ LL GA P+ G + + +AA+ GH VA+F L GA L + G L+ V+ E L+ + + K G T L A +N+++ L+LL GA P+ K G TPL A I + L+ G D N R G +VH AA+ G+ + L + A ++ + + P+H AA
Sbjct: 465 VRYLVQDGAQ--VEAKAKDD-QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLAAREGHEDVAAF--LLDHGASLSITTKKGFTPLH--VAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAH--YDNQKVALLLLDQGASPHAAAK-NGYTPLHIAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAA 688 HSP 8 Score: 73.1738 bits (178), Expect = 1.125e-11 Identity = 56/170 (32.94%), Postives = 80/170 (47.06%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLI--NYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRG 2105
F + A + G + L L+ DT+ + AL AA + L+ + ADV +K F TPLH AAH G I++ LL+N A VD A N TPL A + N+V+ LL +GAKI + GLTPL +V+ ++ +D P+ K G
Sbjct: 157 FTPLAVALQQGHDQVVSLLLEN----DTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGF--TPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEML---LDRSAPILSKTKNG 317 HSP 9 Score: 71.2478 bits (173), Expect = 4.150e-11 Identity = 53/162 (32.72%), Postives = 76/162 (46.91%), Query Frame = 3
Query: 1623 AKHGD-LDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---------KAKVDALP 2078
A GD L+ ++L L+ VD Y TAL AAH G+ + L++ A NAK +TPLH A I ++ELL+ +GA + A +G TP+ A N+V L+ GA N +G T L +A + V+ + KAK D P
Sbjct: 324 ATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKASPNAKALNGFTPLHIACKKNRIRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 485 HSP 10 Score: 63.1586 bits (152), Expect = 1.241e-8 Identity = 74/250 (29.60%), Postives = 107/250 (42.80%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYN-EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNN--VSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQN--NPIHYAAAG-HASCCKFLGQ 953
+K LV NG N N + NG T L +A EN L+ ++FLLD GA + +G + + +A Q GH L + ND GK V + R + AL D N SK G T L A G N + +LL A + + TPL A G+ ++ L G + R G T +H A+SG+ + + L A + T+N +P+H A G H +C + L Q
Sbjct: 106 VKVLVTNGA----NVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGK-VRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNIN--VATLLLNRAAAVDFTAR-NDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRSA--PILSKTKNGLSPLHMATQGDHLNCVQLLLQ 338 HSP 11 Score: 63.1586 bits (152), Expect = 1.398e-8 Identity = 65/265 (24.53%), Postives = 104/265 (39.25%), Query Frame = 3
Query: 231 LVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
L+D+G I + G T L +A L+ LL A PD G + + +AA Y + L GA NG L+ ++ + + + L Y D N V++ G + A ++G + ++ +LL A+ N+ K +G TPL A ++ + G + + G T +H GN K + L A+ + +H AA GH L Q +P NG A IA+ G
Sbjct: 534 LLDHGASLSITTKK---GFTPLHVAAKYGKLEVASLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAKKNQMDIATSLLEYGADANAVTRQGIASVHLAAQEG--HVDMVSLLLSRNANVNLSNK-SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTALHQAAQQGHTHIINVLLQNNASPNELTVNGNTALAIARRLG 790 HSP 12 Score: 62.3882 bits (150), Expect = 1.961e-8 Identity = 46/181 (25.41%), Postives = 81/181 (44.75%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLK---------------------KGAKIQMEN--------SKGLTPLDLAYNWADSRVINIIKAKVDAL 2075
A+K G ++ + L++ VD + TAL A+ G ++ L+ GA+VNA+ +TPL+ AA +++V L++NGA +G TPL A++ VV LL+ K A + ++N G TPL +A ++ + V ++ + A+
Sbjct: 64 ASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAV 244 HSP 13 Score: 56.225 bits (134), Expect = 1.508e-6 Identity = 37/119 (31.09%), Postives = 57/119 (47.90%), Query Frame = 3
Query: 1662 KKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+KG K D + + AA G+L+ + I G DVN + LH A+ G +++V L+ A VDA G T L A + + VV+ L+ GA + ++ G TPL +A
Sbjct: 17 RKGKKSDANASYLR-----AARAGHLEKALDYIKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA 130
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Match: A0A1S3J7J3 (ankyrin repeat and EF-hand domain-containing protein 1 isoform X1 OS=Lingula unguis OX=7574 GN=LOC106170893 PE=4 SV=1) HSP 1 Score: 752.281 bits (1941), Expect = 0.000e+0 Identity = 401/784 (51.15%), Postives = 527/784 (67.22%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVS-PTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIE-KKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE-XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALP-PVKDKKGRGNQKSGRTSSKGRRTAS------------PTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
MPIAQ+RLE+LQ+ K+LQC E D QI+KL NG+ HL+NYN+P G T L+IA N+ + IKFLL+LGAHPDV+DF+G+SA+M AA+YGHV E+LAK GAD+KL DL GK +L+Y +S PT+RH CLE AL Y D+NN+SKDGK V ACE ENE++CL LL+ GADPN +Q+ GKT LMAAC SGS + S L G D N DRH TA+H AAK G F+ L L A+ ++FDV DD N P+H+AA GHA CC+FL QRG NPK+KN+ G + IAKD G KDC KE+ K E+SFGK GKNN+PWA+ LYDW+ EIVE ++ D + SG V K +F++ L APL +E E KK+ DKNKD T DY DFLTGKKY+NKLYLMSAFE GKKKKKK G KGK K+KIP+ ICV PE R GGPP ++IPK + TD RF + PP + ++DD +WY+ PD+T+VN+N+AAK+GDLD+++ A KG VDTRD+++KT LM+A +GN+++ + L++ GAD+NA+DNF WTPLHHA H+G +D+VE L++ GA +DA +NG TPL RAIESS+ +V+FL+ +GAKIQ EN KG PLDLA WAD RV++ ++ K D+LP P K K G+ S +R AS P + P + + ++ RA + L+ + EDI++ P + E L+ + RRQR+GWE+DF D F+ F KN++ + G ED
Sbjct: 1 MPIAQNRLEVLQVCKLLQCVREGDKVQIEKLTLNGIPHLVNYNDPSEGDTALAIAACANNDEMIKFLLELGAHPDVMDFKGRSAVMRAAEYGHVQCMENLAKEGADMKLKDLEGKGILFYVISAPTQRHSRCLEIALEYGADVNNMSKDGKPVFLVACETAAENEDMCLKLLEKGADPNAVQEKEGKTALMAACGSGSVKVVSAILAKGGDVNARDRHRSTALHQAAKGGFFEVLQVLSAYASEFDVVDDKGNTPVHFAADGHAMCCRFLIQRGSNPKLKNNEGVLPKAIAKDNGHKDCGKELRKGEKSFGKTGKNNDPWAIQLYDWSFSRQKEIVEMMQKFDPDISGFVQKDDFIECLQNSGAPLPDEAELKKLTLAHDKNKDNTVDYNDFLTGKKYINKLYLMSAFEGGKKKKKKGGKKGKKGKTKIPMPICVQPEGP--RTAGGGPPEVFIPKNIHFTDNTRFDRDKPPEHPLQDDSAWYLHLPDKTYVNVNEAAKYGDLDTLRNAFSKGSPVDTRDKYFKTPLMTACSHGNMEVAIFLLDQGADINARDNFKWTPLHHACHAGQLDLVEYLLSRGAELDATTMNGGTPLTRAIESSKVELVKFLIDRGAKIQTENKKGQNPLDLAMAWADLRVLDTVQTKWDSLPAPSDKKGKGKGGKGGKKSPPPKRAASAPADKEGDIKFPPVQQRATTPSDEPIRHRKGSILRAASALAGGII--ETEDITYVPLKTWTPQKKTEELIHEKEVRRQRYGWEVDFED-FEMPFLKNISHKCAIFGDED 779
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Match: A0A1S3J7U6 (ankyrin repeat and EF-hand domain-containing protein 1 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106170893 PE=4 SV=1) HSP 1 Score: 723.391 bits (1866), Expect = 0.000e+0 Identity = 366/653 (56.05%), Postives = 471/653 (72.13%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVS-PTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIE-KKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE-XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKD 2090
MPIAQ+RLE+LQ+ K+LQC E D QI+KL NG+ HL+NYN+P G T L+IA N+ + IKFLL+LGAHPDV+DF+G+SA+M AA+YGHV E+LAK GAD+KL DL GK +L+Y +S PT+RH CLE AL Y D+NN+SKDGK V ACE ENE++CL LL+ GADPN +Q+ GKT LMAAC SGS + S L G D N DRH TA+H AAK G F+ L L A+ ++FDV DD N P+H+AA GHA CC+FL QRG NPK+KN+ G + IAKD G KDC KE+ K E+SFGK GKNN+PWA+ LYDW+ EIVE ++ D + SG V K +F++ L APL +E E KK+ DKNKD T DY DFLTGKKY+NKLYLMSAFE GKKKKKK G KGK K+KIP+ ICV PE R GGPP ++IPK + TD RF + PP + ++DD +WY+ PD+T+VN+N+AAK+GDLD+++ A KG VDTRD+++KT LM+A +GN+++ + L++ GAD+NA+DNF WTPLHHA H+G +D+VE L++ GA +DA +NG TPL RAIESS+ +V+FL+ +GAKIQ EN KG PLDLA WAD RV++ ++ K D+LP D
Sbjct: 1 MPIAQNRLEVLQVCKLLQCVREGDKVQIEKLTLNGIPHLVNYNDPSEGDTALAIAACANNDEMIKFLLELGAHPDVMDFKGRSAVMRAAEYGHVQCMENLAKEGADMKLKDLEGKGILFYVISAPTQRHSRCLEIALEYGADVNNMSKDGKPVFLVACETAAENEDMCLKLLEKGADPNAVQEKEGKTALMAACGSGSVKVVSAILAKGGDVNARDRHRSTALHQAAKGGFFEVLQVLSAYASEFDVVDDKGNTPVHFAADGHAMCCRFLIQRGSNPKLKNNEGVLPKAIAKDNGHKDCGKELRKGEKSFGKTGKNNDPWAIQLYDWSFSRQKEIVEMMQKFDPDISGFVQKDDFIECLQNSGAPLPDEAELKKLTLAHDKNKDNTVDYNDFLTGKKYINKLYLMSAFEGGKKKKKKGGKKGKKGKTKIPMPICVQPEGP--RTAGGGPPEVFIPKNIHFTDNTRFDRDKPPEHPLQDDSAWYLHLPDKTYVNVNEAAKYGDLDTLRNAFSKGSPVDTRDKYFKTPLMTACSHGNMEVAIFLLDQGADINARDNFKWTPLHHACHAGQLDLVEYLLSRGAELDATTMNGGTPLTRAIESSKVELVKFLIDRGAKIQTENKKGQNPLDLAMAWADLRVLDTVQTKWDSLPAPSD 651
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Match: A0A1I8JDQ0 (ANK_REP_REGION domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 713.761 bits (1841), Expect = 0.000e+0 Identity = 371/799 (46.43%), Postives = 509/799 (63.70%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLL-DLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKL-LDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE--XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSK-------------------------GRRTASPTKXXXXXXXXXXRSYSELALKRANNLL----SYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASG 2435
MPIA+ R++ LQI K++QC +++ DQI+KLV +G+ L+NY EP +G+T L +A END D ++FL+ ++GA PD D G + M AA+ G V + E+LAKAGAD+K D +GKNVL+YC+ PTERH +C++ AL++ D+N+ + DG+T F ACE +N C LL HGA+P+++Q+A+ +TPLMAACASGS + L G DPN D+ TA HYAAK G+ LVAL +GA FD YD Q NP+H AAA A C KFLGQRGCNPK KN++GE R IAKDKG K+C+KE+ KVE+S+G+ G+N E WAL LYDWTV ++ L+ D SG V ++ ++ L AP E+ KK+ P +DK K+G+FDY DFL KKY+NKLYLMSA+E KK K KKG G+ +K+K P EICVMP+ ++R +GGPP+M++P+ TD RF + PP + ++DD +WY+ P TFVN+NDAAKHGDLDSIKLAL+KGY +TRDR +KT LM AAHYGN+++ L+ GADVNA+DNF WTPLHHA H+G+ID+VELL+ NGA ++A ALNGATPL RAIE+S N+VEFLLK+GAK +E G ++ W + VI+ I+ K P++ K + S G R + + P P E ++R +L + E+ ED++ P+ + +P SLL + RQRFGWE DFPD +++ F +N+ +++ G
Sbjct: 1 MPIARERIDSLQICKLIQCVRDRNRDQIRKLVASGIPQLVNYGEPQDGETPLIVAAKENDEDMVEFLIKEMGALPDFGDRGGVTPAMRAAEQGFVQALEALAKAGADMKARDSSGKNVLFYCIQPTERHAQCMQVALKHEADVNSAANDGRTAFFVACETADKNPACCRALLAHGANPDVVQRASNRTPLMAACASGSAEVALAALMGGADPNRVDKQSWTAAHYAAKGGHLSCLVALSGYGANFDAYDLRQCNPVHEAAAADRALCIKFLGQRGCNPKPKNADGETPRVIAKDKGFKECLKELRKVEKSYGRAGRNCERWALALYDWTVVRGADLQARLQAEFDTSGSGQVTLEDAAQTMLALGAPWTEDCAKKLGPLYDKAKNGSFDYRDFLLAKKYINKLYLMSAYEPKQKKGKGKKGKGGRKKKAKYPFEICVMPDEQMLRTAEGGPPIMFVPQVSNVTDAERFDRDRPPAHPLQDDSAWYVAAPAHTFVNINDAAKHGDLDSIKLALQKGYSTETRDRLFKTPLMVAAHYGNMEVAKFLLEAGADVNARDNFKWTPLHHACHAGLIDMVELLLKNGANIEAVALNGATPLLRAIETSNLNLVEFLLKQGAKASIETKTGEMIHEVVQIWGSAEVIDFIRTKF----PIEAAKDGKGKGSKGGGKGGGKKGAAGGGKKSAKGKGSAKGSEGGARRLADSIVQAPAPAPRIEDEEEAHIRRKARILHDANALDGGYEEAEDVTAHPKGHWLEQPDTGSLLASKSRYRQRFGWESDFPD-YRNPFQRNIWNKLEVEG 794
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Match: A0A267GTK0 (ANK_REP_REGION domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig028661g2 PE=4 SV=1) HSP 1 Score: 713.375 bits (1840), Expect = 0.000e+0 Identity = 371/799 (46.43%), Postives = 509/799 (63.70%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLL-DLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKL-LDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE--XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSK-------------------------GRRTASPTKXXXXXXXXXXRSYSELALKRANNLL----SYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASG 2435
MPIA+ R++ LQI K++QC +++ DQI+KLV +G+ L+NY EP +G+T L +A END D ++FL+ ++GA PD D G + M AA+ G V + E+LAKAGAD+K D +GKNVL+YC+ PTERH +C++ AL++ D+N+ + DG+T F ACE +N C LL HGA+P+++Q+A+ +TPLMAACASGS + L G DPN D+ TA HYAAK G+ LVAL +GA FD YD Q NP+H AAA A C KFLGQRGCNPK KN++GE R IAKDKG K+C+KE+ KVE+S+G+ G+N E WAL LYDWTV ++ L+ D SG V ++ ++ L AP E+ KK+ P +DK K+G+FDY DFL KKY+NKLYLMSA+E KK K KKG G+ +K+K P EICVMP+ ++R +GGPP+M++P+ TD RF + PP + ++DD +WY+ P TFVN+NDAAKHGDLDSIKLAL+KGY +TRDR +KT LM AAHYGN+++ L+ GADVNA+DNF WTPLHHA H+G+ID+VELL+ NGA ++A ALNGATPL RAIE+S N+VEFLLK+GAK +E G ++ W + VI+ I+ K P++ K + S G R + + P P E ++R +L + E+ ED++ P+ + +P SLL + RQRFGWE DFPD +++ F +N+ +++ G
Sbjct: 2 MPIARERIDSLQICKLIQCVRDRNRDQIRKLVASGIPQLVNYGEPQDGETPLIVAAKENDEDMVEFLIKEMGALPDFGDRGGVTPAMRAAEQGFVQALEALAKAGADMKARDSSGKNVLFYCIQPTERHAQCMQVALKHEADVNSAANDGRTAFFVACETADKNPACCRALLAHGANPDVVQRASNRTPLMAACASGSAEVALAALMGGADPNRVDKQSWTAAHYAAKGGHLSCLVALSGYGANFDAYDLRQCNPVHEAAAADRALCIKFLGQRGCNPKPKNADGETPRVIAKDKGFKECLKELRKVEKSYGRAGRNCERWALALYDWTVVRGADLQARLQAEFDTSGSGQVTLEDAAQTMLALGAPWTEDCAKKLGPLYDKAKNGSFDYRDFLLAKKYINKLYLMSAYEPKEKKGKGKKGKGGRKKKAKYPFEICVMPDEQMLRTAEGGPPIMFVPQVSNVTDAERFDRDRPPAHPLQDDSAWYVAAPAHTFVNINDAAKHGDLDSIKLALQKGYSTETRDRLFKTPLMVAAHYGNMEVAKFLLEAGADVNARDNFKWTPLHHACHAGLIDMVELLLKNGANIEAVALNGATPLLRAIETSNLNLVEFLLKQGAKASIETKTGEMIHEVVQIWGSAEVIDFIRTKF----PIEAAKDGKGKGSKGGGKGGGKKGAAGGGKKSAKGKGSAKGSEGGARRLADSIVQAPAPAPRIEDEEEAHIRRKARILHDANALDGGYEEAEDVTAHPKGHWLEQPDTGSLLASKSRYRQRFGWESDFPD-YRNPFQRNIWNKLEVEG 795
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Match: A0A210QF97 (Ankyrin repeat and EF-hand domain-containing protein 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT10323 PE=4 SV=1) HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0 Identity = 373/776 (48.07%), Postives = 507/776 (65.34%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELAL---KRANNLL----SYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
MP+AQ+RLE LQ+ K+LQC K+ +QI+K+ NG+ HLINYN+ G T L +A + ND + I+FLL+LGAHPDV DF+G++A M AA++GHV E L KAGAD+K DL GK +L+YC+SPTERH +CLE A+ + NN+S+DG V ACE ENE+ CL+LL+ G+DPN Q+ TGKT LMAA SGS + L+ G D N D A HYAA +G F+ L + A+GA FD ++ N PIH AA GHA CCKFL QRGCNPK KN++GE A+++AK+K K+ KE+ K E++FGK+GKNNEPWA+ LYDW +E +I+ K D + G V K EF D L+ + AP E K++ DK +DG DY DFLTGKK++NK YLMSAFEGKKKKKKKGGKGK +K K + + + R G PP M+I + + TD RF + PP + ++DD +WY+ P++ ++N+NDA K+GD DS+K A +KG VDTRD++YKT LM A GN+DM L+ GA +NA+DNF WTPLHHA HSG +D+V L++NGA ++A +NG TPL RAIESSR +V +L+ +GAK+Q EN KG +PLDLA +WAD RV+N ++A+ D LP K + G S R T+ P ++ P S S L +R ++L + +S ++ EDI++ P +P + L+Q + RR R+GWE+DFPD F+ F KN+T++ A G +D
Sbjct: 1 MPVAQTRLETLQVCKLLQCVRMKEKNQIEKMTVNGIPHLINYNDASEGLTALGVAAAANDDEMIEFLLELGAHPDVPDFKGRTAAMRAAEFGHVQCLEKLTKAGADMKSIDLEGKGILFYCISPTERHAKCLELAVVNGAESNNMSRDGIPVFMFACETAAENEDACLLLLEKGSDPNGKQEKTGKTCLMAASLSGSVKVVRAILEAGGDVNVLDIQHTHAAHYAALTGGFEVLACMSAYGAVFDQCNNKGNTPIHNAALNGHAMCCKFLWQRGCNPKPKNNDGETAKSLAKEKDQKEAGKELRKAEKAFGKVGKNNEPWAIVLYDWVMEQSQKILNAYKRFDPDEKGTVQKDEFSDTLVGMSAPAEEADIAKVMTLHDKARDGNIDYNDFLTGKKWMNKNYLMSAFEGKKKKKKKGGKGKGKKGKFKLAMPICTSEEGPRTYGGAPPEMFIERHIHFTDTGRFDRDRPPKHPLQDDSAWYLQHPEKMYININDATKNGDFDSLKGAFQKGTPVDTRDKYYKTPLMVACSIGNIDMVKFLLENGAYINARDNFKWTPLHHACHSGQLDVVSFLLDNGAELEAHTMNGGTPLTRAIESSREGLVTYLVDRGAKLQTENKKGHSPLDLANSWADPRVLNFMQARCDGLPAGDKKGKGKGKGKGGQKS-ARPTSVPPPADKENTGPIPFSASGEDLPSRQRKGSILRAASALASGVDEEEDITYIPLKAWTKQPTSQELIQEKRVRRDRYGWEVDFPD-FEMPFMKNVTKKNVAMGDDD 774
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Match: ankef1a (ankyrin repeat and EF-hand domain-containing protein 1-like [Source:NCBI gene;Acc:103043611]) HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0 Identity = 323/776 (41.62%), Postives = 460/776 (59.28%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKL----GKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIV-----NKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE-XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGR------TSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERV 2423
+A RLE LQI ++LQ E + QI++LV+ GV+ LIN EP GK L +A+ ND D ++FL+ GA PDV D G++ +M+AA+ GH LAK AD+KL D+ GK VL+YCV PT+RH CL+ AL D+NNVS+ G +L ACE+ E E +CL LL+ GADPN + TG T LM A +G+ + LK G + N +D AVH+AA+ G F+ + L A+ A N +HYAA G A+CC+FL QRGCN K+KN G R IAKD G K +KE+ + ER GK G NEPWAL L+DW+ E+ ++ K D + GIV +++ FV +L LKAP+ +E ++IL D+ ++G + DFL G +Y+ K ++M+++E KKK+ KGGK K K +P+ IC +P + R DGGPP I TD NRF ++PP + +EDD +WY+ DP + +VN++ K GD+ S+KLA + VD +D++YKT LM+A GN ++ L++ GADVNA+D F WTPLHHA H+G +DI+ELL+ GA VDA AL+GATPL RAIES R V++LLK GA + +EN LD+A +AD R++ +I+AK+++L +DKK + + R SSK ++ AS T + +++ N + DISF PR + + L++ + ERRQRF E+DF D F+ F+KNL ++
Sbjct: 5 VADGRLEELQIYRLLQYVQESNKGQIERLVNMGVDDLINLTEPLEGKGVLYLASVANDTDMVEFLIGQGARPDVQDKRGRTPVMLAAELGHDGVVSLLAKKNADMKLVDVEGKGVLFYCVFPTKRHMRCLQAALNSMADVNNVSQAGVPLLMQACENALECEGMCLSLLERGADPNATNQVTGCTALMEAVKAGAVGLVRAILKRGANVNASDTKNFQAVHFAAELGYFEIIRVLSAYAADMGGITAEGNTALHYAAHGGFANCCRFLAQRGCNLKLKNLEGLLPRQIAKDLGHKASLKELKRAERLHGKFSKGSGGTNEPWALTLHDWSHEHEADL---RKAFDSASDGIVGIEVVSRQTFVSVLRGLKAPVEDEHIQRILIAHDRRREGLINIIDFLKGFRYLPKSFVMASYEPRKKKRAAKGGKTKKIKLNLPLPICTVPPELLYRRDDGGPPHFMIENYHLITDPNRFDRDHPPGHPVEDDSAWYVDDPGKVYVNISYCVKTGDIASLKLAFSQKVPVDVKDQYYKTPLMTACGSGNYEVAKFLLDLGADVNARDQFSWTPLHHACHAGQLDIIELLVEAGAAVDAPALSGATPLMRAIESCRPCCVDYLLKAGATVTVENKTEQNCLDIARAYADQRIVELIQAKMNSLYKARDKKDKAAKPQTRPRPLTSMSSKEKQGASSTAKTTVKADSVILHSTQITSGTLNKV-----------DISFQPRTVWGKQLTTRQLMEKKEERRQRFTSEVDFED-FRMPFNKNLRKKT 765
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Match: ankef1a (ankyrin repeat and EF-hand domain-containing protein 1-like [Source:NCBI gene;Acc:103043611]) HSP 1 Score: 571.237 bits (1471), Expect = 0.000e+0 Identity = 323/776 (41.62%), Postives = 460/776 (59.28%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKL----GKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIV-----NKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE-XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGR------TSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERV 2423
+A RLE LQI ++LQ E + QI++LV+ GV+ LIN EP GK L +A+ ND D ++FL+ GA PDV D G++ +M+AA+ GH LAK AD+KL D+ GK VL+YCV PT+RH CL+ AL D+NNVS+ G +L ACE+ E E +CL LL+ GADPN + TG T LM A +G+ + LK G + N +D AVH+AA+ G F+ + L A+ A N +HYAA G A+CC+FL QRGCN K+KN G R IAKD G K +KE+ + ER GK G NEPWAL L+DW+ E+ ++ K D + GIV +++ FV +L LKAP+ +E ++IL D+ ++G + DFL G +Y+ K ++M+++E KKK+ KGGK K K +P+ IC +P + R DGGPP I TD NRF ++PP + +EDD +WY+ DP + +VN++ K GD+ S+KLA + VD +D++YKT LM+A GN ++ L++ GADVNA+D F WTPLHHA H+G +DI+ELL+ GA VDA AL+GATPL RAIES R V++LLK GA + +EN LD+A +AD R++ +I+AK+++L +DKK + + R SSK ++ AS T + +++ N + DISF PR + + L++ + ERRQRF E+DF D F+ F+KNL ++
Sbjct: 5 VADGRLEELQIYRLLQYVQESNKGQIERLVNMGVDDLINLTEPLEGKGVLYLASVANDTDMVEFLIGQGARPDVQDKRGRTPVMLAAELGHDGVVSLLAKKNADMKLVDVEGKGVLFYCVFPTKRHMRCLQAALNSMADVNNVSQAGVPLLMQACENALECEGMCLSLLERGADPNATNQVTGCTALMEAVKAGAVGLVRAILKRGANVNASDTKNFQAVHFAAELGYFEIIRVLSAYAADMGGITAEGNTALHYAAHGGFANCCRFLAQRGCNLKLKNLEGLLPRQIAKDLGHKASLKELKRAERLHGKFSKGSGGTNEPWALTLHDWSHEHEADL---RKAFDSASDGIVGIEVVSRQTFVSVLRGLKAPVEDEHIQRILIAHDRRREGLINIIDFLKGFRYLPKSFVMASYEPRKKKRAAKGGKTKKIKLNLPLPICTVPPELLYRRDDGGPPHFMIENYHLITDPNRFDRDHPPGHPVEDDSAWYVDDPGKVYVNISYCVKTGDIASLKLAFSQKVPVDVKDQYYKTPLMTACGSGNYEVAKFLLDLGADVNARDQFSWTPLHHACHAGQLDIIELLVEAGAAVDAPALSGATPLMRAIESCRPCCVDYLLKAGATVTVENKTEQNCLDIARAYADQRIVELIQAKMNSLYKARDKKDKAAKPQTRPRPLTSMSSKEKQGASSTAKTTVKADSVILHSTQITSGTLNKV-----------DISFQPRTVWGKQLTTRQLMEKKEERRQRFTSEVDFED-FRMPFNKNLRKKT 765
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Match: ankef1a (ankyrin repeat and EF-hand domain-containing protein 1-like [Source:NCBI gene;Acc:103043611]) HSP 1 Score: 551.592 bits (1420), Expect = 0.000e+0 Identity = 320/770 (41.56%), Postives = 448/770 (58.18%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKL----GKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIV-----NKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE-XXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERV 2423
+A RLE LQI ++LQ E + QI++LV+ GV+ LIN EP GK L +A+ ND D ++FL+ GA PDV D G++ +M+AA+ GH LAK AD+KL D+ GK VL+YCV PT+RH CL+ AL D+NNVS+ G +L ACE+ E E +CL LL+ GADPN + TG T LM A +G+ + LK G + N +D AVH+AA+ G F+ + L A+ A N +HYAA G A+CC+FL QRGCN K+KN G R IAKD G K +KE+ + ER GK G NEPWAL L+DW+ E+ ++ K D + GIV +++ FV +L LKAP+ +E ++IL D+ ++G + DFL G +Y+ K ++M+++E KKK+ KGGK K K +P+ IC +P + R DGGPP I TD NRF ++PP + +EDD +WY+ DP + +VN++ K GD+ S+KLA + VD +D++YKT LM+A GN ++ L++ GADVNA+D F WTPLHHA H+G +DI+ELL+ GA VDA AL+GATPL RAIES R V++LLK GA + +EN LD+A +AD R++ +I+AK+++L +DKK + A P R L S SSK E + T R L++ + ERRQRF E+DF D F+ F+KNL ++
Sbjct: 5 VADGRLEELQIYRLLQYVQESNKGQIERLVNMGVDDLINLTEPLEGKGVLYLASVANDTDMVEFLIGQGARPDVQDKRGRTPVMLAAELGHDGVVSLLAKKNADMKLVDVEGKGVLFYCVFPTKRHMRCLQAALNSMADVNNVSQAGVPLLMQACENALECEGMCLSLLERGADPNATNQVTGCTALMEAVKAGAVGLVRAILKRGANVNASDTKNFQAVHFAAELGYFEIIRVLSAYAADMGGITAEGNTALHYAAHGGFANCCRFLAQRGCNLKLKNLEGLLPRQIAKDLGHKASLKELKRAERLHGKFSKGSGGTNEPWALTLHDWSHEHEADL---RKAFDSASDGIVGIEVVSRQTFVSVLRGLKAPVEDEHIQRILIAHDRRREGLINIIDFLKGFRYLPKSFVMASYEPRKKKRAAKGGKTKKIKLNLPLPICTVPPELLYRRDDGGPPHFMIENYHLITDPNRFDRDHPPGHPVEDDSAWYVDDPGKVYVNISYCVKTGDIASLKLAFSQKVPVDVKDQYYKTPLMTACGSGNYEVAKFLLDLGADVNARDQFSWTPLHHACHAGQLDIIELLVEAGAAVDAPALSGATPLMRAIESCRPCCVDYLLKAGATVTVENKTEQNCLDIARAYADQRIVELIQAKMNSLYKARDKKDKA--------------AKPQ-------------------TRPRPLTSMSSK-EKVWGKQLTTR----------QLMEKKEERRQRFTSEVDFED-FRMPFNKNLRKKT 726
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Match: ankef1b (ankyrin repeat and EF-hand domain-containing protein 1 [Source:NCBI gene;Acc:103034645]) HSP 1 Score: 529.25 bits (1362), Expect = 1.418e-175 Identity = 301/784 (38.39%), Postives = 444/784 (56.63%), Query Frame = 3
Query: 147 IAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKN-----NEPWALGLYDWTVENMTEIVEELKLLDLENSGI--VNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXX-------XIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPE-----DIEDISFTPRYLLVNR-----PHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERV 2423
+A+ RLE+LQ+ K+LQ E+D Q++KL+ GV LIN EP GK + + NDLD ++LL+ A+PD+ D GK+ ++++A+ GH LA+ A++ + D GK VL+YC+SPT+RH +CL+ AL D+N+VS+ G+ V ACE E E + L LL+ GADPN + TG+T LM A G+ + L+ G +PN+ D + + A H AA+ G F+ + L A+ A F+ D P+H AAAG H+ CC+FL QRGCNPK+KN +G R IAKD G + +KE+ + E+ K K N PWA+ L+DW+ E+ + + + ++ FV +L +AP++ + + IL D DGT + DF G KY+ K +++S++ K KKK+ GK K +P+ IC +P + R DGGPP I Q TD RFS + PP++ +EDD +WY+ +P+R + N+N K GD +S+ LA + VD RD FYKT LM+A YG+ M L+ GADVNA D F+WTPLHHA H+G +DI++LL+ GA VD ALNGATPL RAIES R + V++L+ GA +Q +N K + LD+A + D R+I ++K K+D++ D K R +S +T SK A PT P E + N+++ + + + DI FTPR + R H+E + +RR+R E+DF D F F KN+ ++
Sbjct: 6 VAEGRLEVLQVYKLLQFVRERDKTQLEKLIRLGVPDLINRTEPAEGKGAMHLVALTNDLDMAQYLLNHRANPDIQDKRGKTPVILSAELGHEGMVALLAQYHANMNVEDNEGKGVLFYCISPTKRHAQCLQVALSSRADVNSVSRAGQPVFLLACEHAGECEGMALSLLEMGADPNATHQVTGRTALMEASRLGAVGLVRAILQKGGNPNSIDTNRQYAAHLAAQGGYFEVIQVLSAYCADFNAVDLKGETPLHLAAAGGHSDCCRFLSQRGCNPKLKNLDGLLPRQIAKDNGHRAALKELKRAEKLHAKFSKPGAKNPNAPWAVTLHDWSCEHQNLLRNAFGTAAGADGPVDSISGDVFVSVLQEHRAPVDPDNLQNILQNHDSKGDGTVNLNDFFKGLKYLQKTFVLSSYATKTKKKQNKKGGKGGKKGKKKGKLVVPLPICTVPPERMPRREDGGPPGYMIESYQQFTDARRFSRDCPPNHPLEDDSAWYLEEPERIYTNINRCVKTGDFESLCLAFSQQIPVDVRDPFYKTPLMTACSYGSYQMTKFLLMVGADVNACDQFNWTPLHHACHAGQVDIIDLLVRTGANVDTAALNGATPLMRAIESCRISCVDYLINAGAAVQAQNKKEQSCLDVARAFGDERIIEMVKMKLDSVSKPADGKERS--RSSKTRSK---PAPPTAVKVAPALSVP---VEKKVNLMENIITVNPRSSITPSINRPDIRFTPRTVWGQRLANSAQHMER----KVDRRKRLTHEVDFTD-FLMPFSKNILQKT 776
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Match: ank3a (ankyrin 3a [Source:ZFIN;Acc:ZDB-GENE-060621-1]) HSP 1 Score: 122.479 bits (306), Expect = 8.538e-28 Identity = 147/626 (23.48%), Postives = 247/626 (39.46%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRP----IDGGPPVMYIPKE---QYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVD----ALPPVKDK 2093
N T L +A + + +K LLD GA D +G + + A+ GH E L GA + NG + L+ H C++ L+++V +++V+ D T L A G + ++ +++ A+PN + G TPL AC + LK G G T +H AA G+ + L GA + + +H AA AG A ++L Q G +K + + A IA G E++++ G W T L L E +E LL+ A L+ +K P K G + A L GK + L++ + ++ + + ++ H P +G P+ K+ + T L F +E N + + ++ AA+ G +D + L L K V+ ++ T L AA + + L+N+GA+V+A +TPLH A H G + +V L+ N A +++K +G TPL +A + +++ LL+ A G T L +A V++ ++ D A PPV +K
Sbjct: 241 NDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGD--HLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCG--HYKVAKVIVDKKANPNA-KALNGFTPLHIACKKNRVKVMELLLKHGASLQAVTESGLTPIHVAAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKA----EIVQLLLQKGA--------------WASAATTSGYTPLHLAVREG-----HQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQKRAAPDTAGKTGLTPLHVAAHYDNQ-------------------RVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAET---NAVTR----------QGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNGLTPLHLAAQEDRVGVAEVLLNHGAEVDAHTKTGYTPLHVACHYGNMKMVSFLLENQAKINSKTKSGYTPLHQAAQQGHTHIINMLLQHRASANELTLNGNTALSIARRLGYISVVDTLRGLTDENLTATPPVSEK 806 HSP 2 Score: 85.5001 bits (210), Expect = 1.890e-16 Identity = 50/158 (31.65%), Postives = 86/158 (54.43%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
+G+ R+ + AA+ G+L+ LK G ++ ++ AL A+ G++++ L+ GA V+A T LH A+ +G D+V L+ NGA V+A++ NG TPL+ A + + VV FLL+ GA + G TPL +A +V++++
Sbjct: 1 MGNSSRSNASYLRAARAGNLEKALDYLKTGVDINICNQNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLL 158 HSP 3 Score: 84.7297 bits (208), Expect = 3.921e-16 Identity = 53/141 (37.59%), Postives = 74/141 (52.48%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYK--------TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
AA+ D S L L+ + D + + T L AAHYGN+++ L+N GA V+ TPLH AA G ++V+LL++ GA +DAK +G TPL S VVE LL +GA I + GL+PL +A
Sbjct: 175 AARKDDTKSAALLLQNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMA 315 HSP 4 Score: 80.4925 bits (197), Expect = 7.777e-15 Identity = 71/257 (27.63%), Postives = 113/257 (43.97%), Query Frame = 3
Query: 237 DNGVEHLINYNEPDN-----GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNG 989
+N V+ L ++ N G+T L +A D +++LL GA D+ + ++A+ IA++ G + L + GA +G L+ V E H+E L + L+ +K G T L A + G+ E +LL+ A P+ K TG TPL A + + L G P+ A ++G T +H AAK + L FGA+ + +P+H AA G L + N + N NG
Sbjct: 420 ENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVR--EGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQI--EAAKLLLQKRAAPDTAGK-TGLTPLHVAAHYDNQRVALLLLDHGASPHAAAKNGYTPLHIAAKKNQLEIGTTLLEFGAETNAVTRQGISPLHLAAQEGSVDLVSLLLTKNANVNMGNKNG 671 HSP 5 Score: 80.1073 bits (196), Expect = 8.908e-15 Identity = 50/151 (33.11%), Postives = 78/151 (51.66%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
F ++ AA +G+++ L L +G VD R T L AA GN +M L++ GA ++AK TPLH A SG +VE+L++ GA + +K NG +PL A + N V+ LL+ + + LT L +A + +V +I
Sbjct: 210 FTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHDVPVDDVTNDYLTALHVAAHCGHYKVAKVI 360 HSP 6 Score: 70.8626 bits (172), Expect = 6.368e-12 Identity = 50/160 (31.25%), Postives = 71/160 (44.38%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
AA G + +K G +T + +TAL AA G D+ +L+ GA V+ K T LH A+ G +IV+LL+ GA A +G TPL A+ LL+ GA + KG TPL +A + ++ K A P K G
Sbjct: 414 AAFMGHENIVKQLTHHGASPNTTNVRGETALHMAARAGQADVVRYLLQNGAKVDIKAKDDQTALHIASRLGKAEIVQLLLQKGAWASAATTSGYTPLHLAVREGHQETASLLLEHGASLSAATKKGFTPLHVAAKYGQIEAAKLLLQK-RAAPDTAGKTG 572 HSP 7 Score: 70.0922 bits (170), Expect = 1.050e-11 Identity = 81/334 (24.25%), Postives = 131/334 (39.22%), Query Frame = 3
Query: 156 SRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDG---------------------------KENEEICLILLKHGADPNIIQKA-------TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
SR +R EK D +K VD IN NG L +A+ E ++ + LL LGA D +G +A+ IA+ G L GA++ NG LY ++ E H E + L + + ++DG T L A + G K++ + +LL++ + ++ K +G TPL A G+ ++ + L G + R+ T +H AAK GN + L GA+ D P+H A +GH + L RG K NG +A +C++ +++
Sbjct: 5 SRSNASYLRAARAGNLEKALDYLKTGVD------INICN-QNGLNALHLASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLY--MAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVESKVHTYTHTHSGFTPLHIAAHYGNINVATLLLNRGAAVDFMARNDITPLHVAAKRGNGNMVKLLLDRGAKIDAKTKDGLTPLHCGARSGHEQVVEMLLDRGAPILSKTKNGLSPLHMATQGDHLNCVQLLLQ 329 HSP 8 Score: 64.6994 bits (156), Expect = 4.117e-10 Identity = 39/118 (33.05%), Postives = 60/118 (50.85%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK 1973
A+K G ++ + LK G VD + TAL A+ G D+ L+ GA+VNA+ +TPL+ AA +++V L+ +GA +G TPL A++ VV LL+ K
Sbjct: 47 ASKEGHVEVVAELLKLGASVDAATKKGNTALHIASLAGQTDVVRELVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLEHGASQSIATEDGFTPLAVALQQGHDQVVSLLLENDTK 164
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ankef1b (ankyrin repeat and EF-hand domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-060810-68]) HSP 1 Score: 344.739 bits (883), Expect = 1.810e-108 Identity = 210/559 (37.57%), Postives = 303/559 (54.20%), Query Frame = 3
Query: 834 KSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSF---------GKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQ-FDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXX-XIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSW-YIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSY---------SSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
K L L A GA + + +H AA GH CC+FL QRGCNPK+KN+ + AR +AK+ G K +K + K ER F GK G ++PWA+ LYDWT E ++ EL + G + ++ +D L R +AP E ++L Q D NK GT +FL G KY+ K YLMSAFE K +K KKG + K +P+ ICV+PE R DGGPP+ I + +TD RF ++ P + IEDD +W Y+ P+RTFV + A + GD +S+ A + VD RD FYKT LM+AA +GN+++ HL+ GADV A+D + WT LHHA H+G DI LL++ GA +A L G+T L RA ES R + V LL++GA++ N + T L++A + + R+ +++A+ DALP K+ +G GN+K G + R +S LA K + + + + + +++FTPR ++ +LL + RQRF +IDFP FQ F K +T+R G D
Sbjct: 1 KVLQVLAAMGADLGLVALDGSTALHLAALKGHTVCCRFLAQRGCNPKLKNAERQTARMLAKESGHKATVKALRKEERLFSRSQRPPADGKKGVCSQPWAVRLYDWTQEYKEDLRAELGAV-CGPDGSLASEQLLDALRRQRAPPLGPPETQLLLQAHDLNKSGTVVLEEFLKGNKYLAKSYLMSAFEPKGRKGKKGRRKGKAKKFTVPLPICVVPEGVTPRRADGGPPLHAIEQLSLTTDCGRFDRDHRPAHPIEDDSAWSYMAAPERTFVGVTAAVRGGDCESLLRAFSQDVPVDVRDPFYKTPLMAAAAHGNMELAAHLLQLGADVQARDAYRWTALHHACHAGQADIAALLLDAGAEANAMTLGGSTALMRAAESGRLDCVTLLLERGARLAQRNKQDNTALEVAQAFGEPRITAVLQARFDALPRAKESRG-GNRKKGDLQAASARASSRPHTSPTEASSQPARDQRLADKLQPKMKATPPPRASPFATDRRANQINVTFTPRTDWRSQASTPALLHQKESLRQRFSEDIDFPG-FQMPFQKGVTQRAALFGALD 556
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ankef1b (ankyrin repeat and EF-hand domain containing 1b [Source:ZFIN;Acc:ZDB-GENE-060810-68]) HSP 1 Score: 261.536 bits (667), Expect = 4.798e-79 Identity = 158/414 (38.16%), Postives = 228/414 (55.07%), Query Frame = 3
Query: 1212 LIRLKAPLNEEIEKKILPQ-FDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXX-XIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSW-YIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
L R +AP E ++L Q D NK GT +FL G KY+ K YLMSAFE K +K KKG + K +P+ ICV+PE R DGGPP+ I + +TD RF ++ P + IEDD +W Y+ P+RTFV + A + GD +S+ A + VD RD FYKT LM+AA +GN+++ HL+ GADV A+D + WT LHHA H+G DI LL++ GA +A L G+T L RA ES R + V LL++GA++ N + T L++A + + R+ +++A+ DALP K+ +G GN+K G + R +S LA K +++++ I F +Y ++ +LL + RQRF +IDFP FQ F K +T+R G D
Sbjct: 2 LRRQRAPPLGPPETQLLLQAHDLNKSGTVVLEEFLKGNKYLAKSYLMSAFEPKGRKGKKGRRKGKAKKFTVPLPICVVPEGVTPRRADGGPPLHAIEQLSLTTDCGRFDRDHRPAHPIEDDSAWSYMAAPERTFVGVTAAVRGGDCESLLRAFSQDVPVDVRDPFYKTPLMAAAAHGNMELAAHLLQLGADVQARDAYRWTALHHACHAGQADIAALLLDAGAEANAMTLGGSTALMRAAESGRLDCVTLLLERGARLAQRNKQDNTALEVAQAFGEPRITAVLQARFDALPRAKESRG-GNRKKGDLQAASARASSRPHTSPTEASSQPARDQRLADKITALVIAFAENRTQI--TIFLGKYDWRSQASTPALLHQKESLRQRFSEDIDFPG-FQMPFQKGVTQRAALFGALD 411
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009608.1 (pep scaffold:Pmarinus_7.0:GL477242:23155:61557:-1 gene:ENSPMAG00000008655.1 transcript:ENSPMAT00000009608.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.931 bits (289), Expect = 1.624e-26 Identity = 167/648 (25.77%), Postives = 259/648 (39.97%), Query Frame = 3
Query: 258 INYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDL---------NGKN-------VLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLF----HACEDGKENEEICLILLKHGADP-NIIQKATGKTPLMAACAS---GSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLEN--------SGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPI----DGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
+N + D K T L +A N + ++ LL GA D G + A YGH E L K GA + DL KN +L Y PT L + +DL S+ + +++ H+ ++ + G D N T +T L A AS + L+ G + N + T +H A+ + + L GA+ +V D +H AA AGH + C+ L GC+P + + G F ++ + + E R+ + E G D TV+ + + + D+E + N+ V+ L++ A ++ + + ++P + G ++ A+ L + V + + F + KG EIC + H P DG P+ + ++ TD I D R + DAAK G L ++ L G V+ RD + T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI A V+A TPL A + R + LL GA M+N +G TPLDLA D R + I DA+PP
Sbjct: 325 VNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLVKHGASVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPT-----LLNCHSKSAIDLAPTSELKERLVYEFRGHSLLQAAREADVTRVKKHLGLDIINFKHPQTHETALHCAVASPYPKRKQVSELLLRKGANVNEKTKDLLTPLHVASDKAHNDVIDVLLKHGAKINVTDSLGQTSLHRAAHAGHLTTCRLLLSHGCDPNLPSLQG-FTAAQLGNESVQQILHESSLPVRNSDVEHQLLEAAKAGDLD-TVKQLC-TTQTVNCRDMEGRHSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKRGAVVNVADLWKFTPLHEAAAKGK----------YEICKLLLKHGADPTKKNRDGNTPLDLV--KEGDTD---------------------IQDLLRGDAALLDAAKKGCLARVQ-KLCSGENVNCRDSQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYSACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPSMKNQEGQTPLDLA-TADDVRALLI-----DAMPP 924 HSP 2 Score: 105.531 bits (262), Expect = 2.664e-23 Identity = 152/610 (24.92%), Postives = 240/610 (39.34%), Query Frame = 3
Query: 246 VEHLIN-----YNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCM------KEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDR--FYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDL 2015
VEHL+ + D G L A S + + LL GA P+ D + + AA G + L + GAD + + +GK L PT + V KD L A G NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N + + A +A K+ + +++ R + + + L + ++ E + S +K+ +LL+R A +NE+ + + P + D D L K+ K+ + + + + C + SH P +P Q T + +E+ +I + S + + D + +AAK GDLD++K L V+ RD + T L AA Y + + +L+ +GADV+AKD PLH+A G ++ ELL+ GAVV+ L TPL A ++ + + LLK GA +N G TPLDL
Sbjct: 197 VEHLLQNGANVHARDDGGLIPLHNACSFGHAEVVNLLLRQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPGIRNTDGKTALDL-AEPTAK-----------AVLTGEYKKD---ELLEAARSG--NEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLVKHGASVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHSKSAIDLAPTSELKERLVYEFRGHSLLQAARE-ADVTRVKKHLGLDIINFKHPQTHETALHCAVA----SPYPKRKQVSELLLRKGANVNEKTKDLLTPLHVASDKAHNDVIDVLL--KHGAKINVTDSLGQTSLHRAAHAGH--------LTTCRLLLSHGCDP--------NLPSLQGFT-AAQLGNESV--QQILHESSLPVRNSDVEH-QLLEAAKAGDLDTVK-QLCTTQTVNCRDMEGRHSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKRGAVVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 755 HSP 3 Score: 69.707 bits (169), Expect = 2.957e-12 Identity = 48/136 (35.29%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ RD + T L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G T LDLA
Sbjct: 153 EACRNGDVGRVK-RLVSPLNVNARDTTGRKSTPLHFAAGFGRKDVVEHLLQNGANVHARDDGGLIPLHNACSFGHAEVVNLLLRQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPGIRNTDGKTALDLA 287 HSP 4 Score: 64.6994 bits (156), Expect = 7.842e-11 Identity = 93/411 (22.63%), Postives = 157/411 (38.20%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGK-TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKEN--EEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAK-----------------DKGAKDCMKEVIKV-----ERSFGKLGKNNEPWALG-------LYDWTVENMTEIVEELK--LLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL 1313
L C Y + K++ + + N NE T L +A+ + D I LL GA +V D G++++ AA GH+ + L G D L L G + + E ++ L + L + D + L A + G + +++C + D + TPL A S+ L+ G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + K D K C+ V K+ G+N+ P L + ++ +E+ ++ + K L+ L N+ + LLI+ A +N + P + + G L
Sbjct: 490 ALHCAVASPYPKRKQVSELLLRKGANVNEKTKDLLTPLHVASDKAHNDVIDVLLKHGAKINVTDSLGQTSLHRAAHAGHLTTCRLLLSHGCDPNLPSLQG-------FTAAQLGNESVQQIL-HESSLPVRNSDVEHQLLEAAKAGDLDTVKQLCTTQTVNCRD----MEGRHSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKRGAVVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCSGENVNCRDSQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYSACVNATDKWAFTPLHEAAQKGRTQLCALL 888 HSP 5 Score: 60.077 bits (144), Expect = 2.358e-9 Identity = 72/306 (23.53%), Postives = 119/306 (38.89%), Query Frame = 3
Query: 135 NKMPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDN-GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEIC------LILLKHGADPNIIQKATGK------------TPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGE 992
+ +P+ S +E ++L+ D D +K+L +N + + T L A N + +++LL GA D G + A YGH E L K GA + + DL L+ + + E + L++ D ++DG T L E + +++ L K G + + +G+ TPL A + + L+ G D N D+ G +H AA G+ L + A + D P+H AA G C L G +P +KN G+
Sbjct: 607 SSLPVRNSDVE----HQLLEAAKAGDLDTVKQLC---TTQTVNCRDMEGRHSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKRGAVVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDAALLDAAKKGCLARVQKLCSGENVNCRDSQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYSACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPSMKNQEGQ 903 HSP 6 Score: 54.299 bits (129), Expect = 1.282e-7 Identity = 48/186 (25.81%), Postives = 84/186 (45.16%), Query Frame = 3
Query: 1593 DRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLH--------------------HAAHSGMIDIVELLINNGAVVDAKALNG--ATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII---KAKVDAL 2075
D + +++A G + + L L++G + RD + T L AA G +D+C+ L+ +GAD ++ T L AA SG + + L+ V+ A +G +TPL A +R +V+ LL+ GA + ++ GL PL A ++ V ++ A V+A+
Sbjct: 212 DGGLIPLHNACSFGHAEVVNLLLRQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPGIRNTDGKTALDLAEPTAKAVLTGEYKKDELLEAARSGNEEKLMALLTP-LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLVKHGASVNAM 396
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003991.1 (pep scaffold:Pmarinus_7.0:GL484476:255315:281660:1 gene:ENSPMAG00000003623.1 transcript:ENSPMAT00000003991.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 114.775 bits (286), Expect = 3.072e-26 Identity = 164/657 (24.96%), Postives = 264/657 (40.18%), Query Frame = 3
Query: 282 GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE---NEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKL----GVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGK-NNE-----------PWALGLYDWTVENMTEIVEELKLLDLENSGIVNKK-----------------EFVDLLIRLKAPLNEEIEKKILP-QFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVM----YIPKEQYSTDLNRFSSE---NPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNF-HWTPLHHAAHSGMIDIVELLINNG---AVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVIN-IIKAKVDALPPVKDKKGR 2102
G+T L A + + FL+ GA+ + D + + AI AA GH + L GAD++ D G + L+ S + ++ L VD+++ + G T L AC +G++ NE L+ GA+ N + G TPL A AS ++ CL+L G D N + GK+ +H A G F L G + D D N P+H AA GH L G + + +G F +A G DC ++++ + + + +NE P G VE L LL L +NKK + V L+ A LNE+ E++ P + DG F N + + S + + +IC+ H++R D P + Y P + +R E P D S + P ++ AA HG ++++ ++ +D R+ T L AA G+ D LI +GA V K+ T LH AA +G ++ + LL+ N VDA N TP+ A+ + + LL KGA I +++KG T L ++ +++ VD +++++GR
Sbjct: 138 GRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQ--IGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNE-----LIDCGANVNQANE-RGFTPLHFAAASTHGAL---CLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEFGRTCLHAAASGGNVECLNLL-LSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSF----SVYNTISVQSYIDVHSTCSEA-------------QICL---EHLLRK-DADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSDGKSGHPISP------LHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLGLAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDV--SLRERRGR 753 HSP 2 Score: 71.2478 bits (173), Expect = 8.726e-13 Identity = 75/320 (23.44%), Postives = 130/320 (40.62%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG-----------------------HASCC------KFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEP 1094
++ LV+NG + +N D GK+ L + + L+ G D D +G + + IAA+YGH +L GAD ++G L+ ++ +C L + VS + A + +E G+T L AA + G+ + L G D N DR +TA+HYAA + N + +V L A GA+ + D+ + P+HYAAA H++C + L ++ +P +++ G A G + C++ +++ +F GK+ P
Sbjct: 287 LELLVNNGAD--VNVQSKD-GKSPLHMTAVHGRFTRSQTLIQNGGEIDCEDRDGNTPLHIAARYGHELLINTLITNGADTAKRGIHGMFPLH--LAALSGFSDCCRKLLSAGQKYSIVSSFSNEHVLSAGFEIDTPDEF------------------GRTCLHAAASGGNVECLNLLLSTGADMNKKDRFERTALHYAAANCNVQCVVTLVASGARLNEQDERRCTPLHYAAAADGDGSTVSFSVYNTISVQSYIDVHSTCSEAQICLEHLLRKDADPGIQDKQGYTPVHYAAAYGHRVCLELLLEQPGAFQSDGKSGHP 583 HSP 3 Score: 65.855 bits (159), Expect = 3.303e-11 Identity = 47/126 (37.30%), Postives = 67/126 (53.17%), Query Frame = 3
Query: 1680 DTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA-YNWADSRVINII 2054
+ DR +TAL AA G+ +M L+ GA++NA D +H AA+ G ++V++L+ +GA V K G +PL A S + VV+ LL G I NS G T L +A YN D V +I
Sbjct: 132 NVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDKKGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELI 257 HSP 4 Score: 65.0846 bits (157), Expect = 6.412e-11 Identity = 80/329 (24.32%), Postives = 136/329 (41.34%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE-------------------------------NEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGH--ASCCKFLGQRGCNPKVKNSNGE-----------FAR--TIAKDKGAKDC 1034
++Q + D D+++ L+ E +N + D +T L A + + I+ L+ GA + D + + + A A+ ++L K AD+ D N + L+ V+ R +C E + N + G+T L HA +G + E+ +L+ HGAD K G +PL AA +SG + L LGVD + + G TA+H A +G + L GA + ++ P+H+AAA A C + L G + V++ +G+ F R T+ ++ G DC
Sbjct: 10 LIQAIFNGDPDEVRSLIYKKEE--VNAVD-DEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLH--VAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAHGADVRCKDK-KGYSPLHAASSSGQIGVVKLLLDLGVDIDDPNSFGNTALHVACYNGQDVVVNELIDCGANVNQANERGFTPLHFAAASTHGALCLELLVNNGADVNVQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDC 332 HSP 5 Score: 63.929 bits (154), Expect = 1.648e-10 Identity = 49/159 (30.82%), Postives = 75/159 (47.17%), Query Frame = 3
Query: 1590 PDRTFVNMNDAAKHGDLDSIKLALKKG---YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLK----KGAKIQMENSKGLTPLDLA-YNWADSRV 2042
PDR ++ AA +G ++ ++L ++ VD D +T +M A G+ D L++ GA +NAKDN T LH A +G + V+LL+ V + G PL A ++ L++ GA I + + G TPL A YN D V
Sbjct: 648 PDRRTA-LHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCV 805 HSP 6 Score: 61.6178 bits (148), Expect = 7.813e-10 Identity = 48/133 (36.09%), Postives = 68/133 (51.13%), Query Frame = 3
Query: 1710 LMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP--VKDKKGR 2102
L+ A G+ D LI +VNA D+ TPLH AA+ G +I+ELL+ +GA V++K TPL RA S V+ LLK A + + TPL +A A +R + +A + L V D+ GR
Sbjct: 10 LIQAIFNGDPDEVRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVA---AANRAVKCAEAIIPMLSSSNVSDRAGR 139 HSP 7 Score: 57.7658 bits (138), Expect = 1.248e-8 Identity = 44/144 (30.56%), Postives = 70/144 (48.61%), Query Frame = 3
Query: 1632 GDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK 2063
GD D ++ + K +V+ D +T L +AA+ G ++ L+ GA VN+KDN TPLH A S V+ L+ + A V+A+ N TPL A + E ++ + + + G T L A S ++N + AK
Sbjct: 17 GDPDEVRSLIYKKEEVNAVDDEKRTPLHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAK 160 HSP 8 Score: 57.7658 bits (138), Expect = 1.269e-8 Identity = 58/209 (27.75%), Postives = 91/209 (43.54%), Query Frame = 3
Query: 330 IKFLLDLGAHPDVVDFEGKSA-----IMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVD-LNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATG---KTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GH 926
++ LL+ P +GKS + +AA +GH + E L ++ DL + + NG L ++ H +C+ +++ L D +T L A +G CL LL AD N A+ +TP+M A +G T S L G N D G TA+H A +G+ + + L + + P+H AAA GH
Sbjct: 564 LELLLE---QPGAFQSDGKSGHPISPLHLAAYHGHHGALEVLIRSLVDLDVREGNGYTPLG--LAALRGHTDCVRVLIQHGASVLLKEGPDRRTALHSAATNGHVE---CLRLLVENADSNEAVDASDANEQTPVMLAVGNGHTDCASLLLSKGASINAKDNKGCTALHRGAATGHEECVDLLLQRSVDVSLRERRGRAPLHMAAACGH 764 HSP 9 Score: 55.0694 bits (131), Expect = 7.124e-8 Identity = 47/163 (28.83%), Postives = 76/163 (46.63%), Query Frame = 3
Query: 1611 MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
++ AA G+ + I+L + G +V+++D + T L A + L+ + ADVNA+D TPLH AA + + E +I + + G T L A + +V FL+ KGA I + K + A + V+ ++ A A KDKKG
Sbjct: 43 LHAAAYLGEAEIIELLVLSGARVNSKDNKWLTPLHRACASRSEAAVQTLLKHSADVNARDKNWQTPLHVAAANRAVKCAEAIIPMLSSSNVSDRAGRTALHHAAFNGHSEMVNFLVAKGANINAFDKKDRRAIHWAAYMGHTEVVKVLVAH-GADVRCKDKKG 204 HSP 10 Score: 48.1358 bits (113), Expect = 9.489e-6 Identity = 63/244 (25.82%), Postives = 100/244 (40.98%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEG---KSAIMIAAQYGHVASFESL---AKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNT----ADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNN---PIHYA 914
I+ LVD V NG T L +A D ++ L+ GA V+ EG ++A+ AA GHV L A + + +D N + + V H +C L +N G T L G +EE +LL+ D ++ ++ G+ PL A A G I S ++ + DR+G T +H+A +G+ + L + DV+ + N P+H A
Sbjct: 603 IRSLVDLDVRE-------GNGYTPLGLAALRGHTDCVRVLIQHGA--SVLLKEGPDRRTALHSAATNGHVECLRLLVENADSNEAVDASDANEQTPVMLAVG--NGHTDCASLLLSKGASINAKDNKGCTALHRGAATG--HEECVDLLLQRSVDVSLRER-RGRAPLHMAAACGHMGILSALVQAAMASGAPIPLTDRNGYTPLHWACYNGHDGCVELLL----ELDVFQKQEGNAFSPLHCA 828
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000095.1 (pep scaffold:Pmarinus_7.0:GL477582:20897:60453:1 gene:ENSPMAG00000000080.1 transcript:ENSPMAT00000000095.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 104.76 bits (260), Expect = 3.225e-23 Identity = 139/613 (22.68%), Postives = 240/613 (39.15%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPH-----NEIE-DDCSWYIGDPDRTFVN-----MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
+G T L IA +++ LL+LGA D G + + +AA+ G+ + L GA + +G L+ C + + H++ +E L + + +K+G + L H G+ + L+L + ++ TPL A G + L G +PN +G T +H A K K + L GA ++ PIH A+ GH + + L Q G + N GE +A G + +K +++ G + ++ L + + K E V LL++ + N P + +++G D A L KK L++ S + + K S K+ + + P H+ D + + + S + P H N++E +G ++ AA+ G D + L L + + + TA+ AA +++ L + ADVN +TPLH A+H G I +V L+ N A+V+AK NG TPL +A + +VV LL+ A + G T L +A V++ +
Sbjct: 204 SGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLH-CAARSG-HEKVIEMLLERDAPILAKTKNGLSPL-HMATQGEHLACVQLLLGRQAPVDDVTLDYL--TPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQT-----------------------PLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTP-LHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYGNIKMVNFLLRNRALVNAKTRNGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLGYISVVDTL 787 HSP 2 Score: 95.9005 bits (237), Expect = 1.814e-20 Identity = 164/661 (24.81%), Postives = 253/661 (38.28%), Query Frame = 3
Query: 216 DQIKKLVDNGVEHLINYN-EPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGK---NVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRA-------------------------------FGAQFDVYDDTQN--NPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL--TGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTR--DRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII-KAKVD 2069
D ++ LV+ G N N + NG T L +A EN L+ +KFLLD GA+ V +G + + +A Q GH L ++ D GK L+ + + L +N D+ SK G T L A G N + +LL GA + + G TPL A G+ ++ L G +T R G T +H AA+SG+ K + L G Q V D T + P+H AA GH K L RG P + NG IA C K IKV K G + ++ T +T I + + V LL++ A N + P ++ G + L +G + K A E + GK+ ++ ++ P + P G +Y + D+ EN D S + F ++ A+K+G L+ L L+K D + + T L A HY + + + L++ GA ++ +TPLH AA +++ ++L+ GA + G PL A + ++V LL + A I + GLT + LA V I+ K K D
Sbjct: 91 DIVRVLVEFGA----NINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLES-------DTKGKVRLPALHIAARKDDTNAAALLLQHEHNADV--TSKSGFTPLHIAAHYGNMN--VATLLLNLGAAVDFTAR-NGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLERDAPILAKTKNGLSPLHMATQGEHLACVQLLLGRQAPVDDVTLDYLTPLHVAAHCGHYRVAKLLLDRGGEPNARALNGFTPLHIA-------CKKNRIKVMELLLKHGAS-------IHTTTESGLTPI---------HVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVK-----AREDQTPLHIASRLGKAEIVQLLLQRGSDPNA----PTASGSTPLYFASREGHGDVASLLLENGA------DISPVT---KKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNGLTPLHVATHYDHQKVALLLLDKGASPHSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMHLAAQEDKVNVAEILTKHKAD 694 HSP 3 Score: 81.2629 bits (199), Expect = 6.247e-16 Identity = 46/145 (31.72%), Postives = 81/145 (55.86%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA++G+L+ + LK G ++T ++ AL A+ G++D+ L+ A+++ T LH AA +G DIV +L+ GA ++A++ NG TPL+ A + + +V+FLL GA + G TPL +A +V+ ++
Sbjct: 18 AARNGNLERLMDHLKGGMDINTCNQNGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLL 162 HSP 4 Score: 78.1814 bits (191), Expect = 4.669e-15 Identity = 58/161 (36.02%), Postives = 84/161 (52.17%), Query Frame = 3
Query: 1647 IKLALKKGYK--------VDTRDRFYKTALMSAAHYGNLDMCMHLINY--GADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
+ +AL++G++ DT+ + AL AA + + L+ + ADV +K F TPLH AAH G +++ LL+N GA VD A NG TPL A + N+V+ LL +GAKI + GLTPL A +VI ++ + DA K K G
Sbjct: 147 LAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGF--TPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGNNNMVKLLLDRGAKIDTKTRDGLTPLHCAARSGHEKVIEMLLER-DAPILAKTKNG 304 HSP 5 Score: 74.3294 bits (181), Expect = 8.340e-14 Identity = 50/157 (31.85%), Postives = 77/157 (49.04%), Query Frame = 3
Query: 1632 GDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK-VDALPPVKDKKG 2099
G L+ ++L L+ G + + +T L A+ G L++ L+ GA V K TPLH A+ G +IV+LL+ G+ +A +G+TPL+ A +V LL+ GA I KG TPL +A + V ++ K A P V + G
Sbjct: 414 GHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKKGFTPLHIASKYGRLEVATLLLEKYASADPKVAGQNG 570 HSP 6 Score: 70.4774 bits (171), Expect = 1.200e-12 Identity = 56/200 (28.00%), Postives = 91/200 (45.50%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAK-----------------------IQMENS------KGLTPLDLAYNWADSRVINI---IKAKVD-----ALPPVKDKKGRGN 2108
A+K G +D + LK+ ++DT + TAL AA G D+ L+ +GA++NA+ +TPL+ AA ++IV+ L++NGA +G TPL A++ VV LL+ K +Q E++ G TPL +A ++ + V + + A VD + P+ RGN
Sbjct: 51 ASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQGHEQVVGLLLESDTKGKVRLPALHIAARKDDTNAAALLLQHEHNADVTSKSGFTPLHIAAHYGNMNVATLLLNLGAAVDFTARNGITPLHVAAKRGN 250 HSP 7 Score: 69.707 bits (169), Expect = 2.039e-12 Identity = 47/164 (28.66%), Postives = 79/164 (48.17%), Query Frame = 3
Query: 1602 FVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDK 2093
F ++ A K + ++L LK G + T T + A+ G+L++ L+ GA NA + TPLH A+ +G +++V+ L+ +GA V KA TPL A + +V+ LL++G+ + G TPL A V +++ + PV K
Sbjct: 371 FTPLHIACKKNRIKVMELLLKHGASIHTTTESGLTPIHVASFMGHLNVVQLLLQNGASSNATNVRGETPLHMASRAGQLEVVKTLLQSGARVGVKAREDQTPLHIASRLGKAEIVQLLLQRGSDPNAPTASGSTPLYFASREGHGDVASLLLENGADISPVTKK 534 HSP 8 Score: 57.3806 bits (137), Expect = 1.434e-8 Identity = 53/188 (28.19%), Postives = 85/188 (45.21%), Query Frame = 3
Query: 264 YNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSG 827
++ NG T L IA +N L+ K LL+LGA +++ +G + + +AAQ GH L A + L G ++ ++ E E ++ D+N +K T L A G N ++ LL++ A N + G TPL A G T + + L+ PN +G TA+ A + G
Sbjct: 597 HSTAKNGYTPLHIAAKKNQLEVGKVLLELGAETNMLTQQGVAPLHLAAQEGHADMVALLLGRHASISLATKGGLTAMH--LAAQEDKVNVAEILTKHKADVNTTTKLCYTPLHVASHYG--NIKMVNFLLRNRALVNAKTR-NGYTPLHQAAQQGHTHVVNALLQHEASPNELTANGNTALAIARRLG 779 HSP 9 Score: 49.2914 bits (116), Expect = 4.395e-6 Identity = 43/148 (29.05%), Postives = 61/148 (41.22%), Query Frame = 3
Query: 582 DGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
D T A +G N E + LK G D N + G L A G + ++ LK + +TA + G TA+H AA +G + L FGA + P++ AA H KFL G N V +G +A +G
Sbjct: 10 DAATSFLRAARNG--NLERLMDHLKGGMDINTCNQ-NGLNALHLASKEGHVDVVTELLKREAEIDTATKVGNTALHIAALAGQTDIVRVLVEFGANINAQSQNGFTPLYMAAQENHLEIVKFLLDNGANQSVATEDGFTPLAVALQQG 154
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Match: HOS4 (Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate [Source:SGD;Acc:S000001374]) HSP 1 Score: 78.5666 bits (192), Expect = 2.613e-15 Identity = 48/112 (42.86%), Postives = 64/112 (57.14%), Query Frame = 3
Query: 1686 RDRFYKTALMSAAHYGNLDMCMHLINYGA-DVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALN--GATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLD 2012
RD +T L A G D+ +I G D+N +DN T LH AA G I+IVELLI NGA V+ K++ G TPL A + +VV++LLK GA + N+KGLT +
Sbjct: 326 RDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTAFE 437 HSP 2 Score: 52.373 bits (124), Expect = 2.829e-7 Identity = 36/99 (36.36%), Postives = 56/99 (56.57%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKG-YKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAK--DNFHWTPLHHAAHSGMIDIVELLINNGA---VVDAKALNG 1898
A G D +K +++G Y ++ +D TAL AA G++++ LI GADVN K + F TPL A+ +G +D+V+ L+ NGA + +AK L
Sbjct: 337 ACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDTPLIDASANGHLDVVKYLLKNGADPTIRNAKGLTA 435 HSP 3 Score: 50.8322 bits (120), Expect = 1.037e-6 Identity = 35/112 (31.25%), Postives = 55/112 (49.11%), Query Frame = 3
Query: 675 IIQKATGKTPLMAACASGSTSIPSKCLKLG-VDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDV-----YDDTQNNP-IHYAAAGHASCCKFLGQRGCNPKVKNSNG 989
I + + G+T L AC G + K ++ G D N D G TA+H AA G+ + + L GA ++ + DT P I +A GH K+L + G +P ++N+ G
Sbjct: 324 IYRDSGGRTRLQIACDKGKYDVVKKMIEEGGYDINDQDNAGNTALHEAALQGHIEIVELLIENGADVNIKSIEMFGDT---PLIDASANGHLDVVKYLLKNGADPTIRNAKG 432
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Match: NAS6 (Evolutionarily conserved 19S regulatory particle assembly-chaperone; proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, also known as p28, which interacts with the Rb tumor suppressor and CDK4/6 [Source:SGD;Acc:S000003464]) HSP 1 Score: 53.1434 bits (126), Expect = 3.544e-8 Identity = 37/109 (33.94%), Postives = 55/109 (50.46%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNG-AVVDAKALNGATPLFRAIESSRFNVVEFLLKK-GAKIQMENSKGLTPLDLAYN 2024
T L A ++ LI GA V KD F+ PLH AA G + ++ELL G + V+ + G TPLF A+ + L++K GA+ + ++KG D+A N
Sbjct: 109 TCLHLAVGKKWFEVSQFLIENGASVRIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYGAEYDLVDNKGAKAEDVALN 217
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Match: PHO81 (Cyclin-dependent kinase (CDK) inhibitor; regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p; relative distribution to the nucleus increases upon DNA replication stress [Source:SGD;Acc:S000003465]) HSP 1 Score: 54.6842 bits (130), Expect = 5.893e-8 Identity = 29/79 (36.71%), Postives = 47/79 (59.49%), Query Frame = 3
Query: 1731 GNLDMCMHLINYGADVNAKDNFH-WTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKK 1964
G+ + LI YGAD N D F+ WTP+ +A SG +++ L+ + A +D + NG +PLF A+ S +V+ LL++
Sbjct: 569 GDPQLIQLLIRYGADPNEIDGFNKWTPIFYAVRSGHSEVITELLKHNARLDIEDDNGHSPLFYALWESHVDVLNALLQR 647
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Match: AKR2 (Ankyrin repeat-containing protein; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p; AKR2 has a paralog, AKR1, that arose from the whole genome duplication [Source:SGD;Acc:S000005560]) HSP 1 Score: 52.7582 bits (125), Expect = 1.981e-7 Identity = 40/120 (33.33%), Postives = 58/120 (48.33%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLI------NNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
TAL AA YGN+ + L+ +GAD KD +H + +S I +V ++ N+ +D+K N TPL A F VE LLK G+ + +++G L A D RVI
Sbjct: 120 TALHWAARYGNIYIVDLLLKHGADPTLKDEQGLNIMHFSVYSSNILLVVYVLYFVVNNNDNVDIDSKDNNNRTPLLWAAYQGDFLTVELLLKFGSTVAWTDNRGFNALHCALVGGDQRVI 239
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Match: AKR1 (Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats; AKR1 has a paralog, AKR2, that arose from the whole genome duplication; any of several human homologs encoding DHHC-type zinc fingers (ZDHHC) can complement temperature sensitivity of yeast akr1 null mutant [Source:SGD;Acc:S000002672]) HSP 1 Score: 48.521 bits (114), Expect = 4.926e-6 Identity = 40/148 (27.03%), Postives = 67/148 (45.27%), Query Frame = 3
Query: 1584 GDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTR-DRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAV-----VDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPL 2009
GD ++ A+ + L + + +G V+ R + T L AA YG + + L+ +GAD D+ + LH + +S I +V ++ N +D + G T L A V LLK GA I++ +++G TPL
Sbjct: 104 GDSTEHITGLHWASINNRLSVVDFLVSQGADVNARAGALHATPLHWAARYGYVYIVDFLLKHGADPTMTDDQGFNLLHLSVNSSNIMLVLYVLFNVVSKGLLDIDCRDPKGRTSLLWAAYQGDSLTVAELLKFGASIKIADTEGFTPL 251
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO28023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7M5]) HSP 1 Score: 67.0106 bits (162), Expect = 1.335e-13 Identity = 36/96 (37.50%), Postives = 55/96 (57.29%), Query Frame = 3
Query: 1773 DVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAV-----VDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
DV+ KD+ WTPLHHAA +G + VE L+ + ++A+ G TPL A R VV+ L++ A + N+KG+T LD+A A++ V+
Sbjct: 1 DVSTKDSSRWTPLHHAAGAGHVRTVETLMRATNIGFSYSLEAEDWRGNTPLMTAAGRGRDRVVQVLIQHKADVTARNAKGMTALDIAIENANATVV 96
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO49269 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH05]) HSP 1 Score: 74.7146 bits (182), Expect = 1.560e-13 Identity = 51/184 (27.72%), Postives = 90/184 (48.91%), Query Frame = 3
Query: 1581 IGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAI-ESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTS 2129
+ + ++ F DA GD+ +++ L +G +D D ++ + A +G D+ L+ GA+VN + TPLH AA G I ++L+ GA V AK TPL ++ + V L++ GA+I N +G+ P+DL + + + ++++ +A K R N SG +S
Sbjct: 415 LSEEEKAFQIAVDAIASGDIAGLEMILDEGLFIDASDHMQRSLIYHAVTFGQADIVQFLLKRGAEVNWEGPEDRTPLHVAAAEGNRTITQMLLAFGANVRAKDSAFCTPLHLSVGKLQNLEVSHLLVEHGARILENNIQGVRPVDLEMQLKEMQRL-LVQSACEAFYSTDLSKSRSN--SGTSS 595
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO41101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5D3]) HSP 1 Score: 66.6254 bits (161), Expect = 2.173e-13 Identity = 38/103 (36.89%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 1773 DVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAV-----VDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI-NIIKAK 2063
DV+ KD+ WTPLHHAA +G + VE L+ + ++A+ G TPL A R VV+ L++ A + N+KG+T LD+A A++ V+ I+K++
Sbjct: 1 DVSTKDSSRWTPLHHAAGAGHVRTVETLMRATNIGFSYSLEAEDWRGNTPLMTAAGRGRDRVVQVLIQHKADVTARNAKGMTALDIAIENANATVVMEILKSE 103
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO41104 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5D3]) HSP 1 Score: 66.6254 bits (161), Expect = 2.173e-13 Identity = 38/103 (36.89%), Postives = 60/103 (58.25%), Query Frame = 3
Query: 1773 DVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAV-----VDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI-NIIKAK 2063
DV+ KD+ WTPLHHAA +G + VE L+ + ++A+ G TPL A R VV+ L++ A + N+KG+T LD+A A++ V+ I+K++
Sbjct: 1 DVSTKDSSRWTPLHHAAGAGHVRTVETLMRATNIGFSYSLEAEDWRGNTPLMTAAGRGRDRVVQVLIQHKADVTARNAKGMTALDIAIENANATVVMEILKSE 103
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Match: EDO36611 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SI88]) HSP 1 Score: 63.1586 bits (152), Expect = 2.183e-12 Identity = 38/90 (42.22%), Postives = 49/90 (54.44%), Query Frame = 3
Query: 1674 KVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNV 1943
+V R+ +TAL A+ G++D LI GA+VN KD WTPLH A + G I IVE LI GA V+ TPL AI ++ V
Sbjct: 1 RVSKRNERGETALHLASIKGDVDELRSLIKAGANVNIKDYAGWTPLHEACNFGHISIVEELIKAGACVNTPGYESITPLHDAIINNHVQV 90 HSP 2 Score: 45.0542 bits (105), Expect = 5.268e-6 Identity = 20/60 (33.33%), Postives = 38/60 (63.33%), Query Frame = 3
Query: 276 DNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGA 455
+ G+T L +A+ + D+D ++ L+ GA+ ++ D+ G + + A +GH++ E L KAGA
Sbjct: 7 ERGETALHLASIKGDVDELRSLIKAGANVNIKDYAGWTPLHEACNFGHISIVEELIKAGA 66
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Match: ankef1a (ankyrin repeat and EF-hand domain containing 1 [Source:NCBI gene;Acc:101165612]) HSP 1 Score: 475.322 bits (1222), Expect = 7.241e-155 Identity = 285/786 (36.26%), Postives = 434/786 (55.22%), Query Frame = 3
Query: 159 RLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNN-------EPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXI--PIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRAN------NLLSYSSKPEDIE-------DISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSY---FHKNLTERVKASGL 2438
RL+ LQI ++LQ ++ ++I+K++ GV +LIN +P+NG L +A S ++LD + FLL GAHPDV D G + +M+AA+ G V L+ + A++++ D GK VL+YC+SP + H CL+ AL D+NNVS +G V CE ICL+++ GADPN TG T LM A +GS + LK G P D+ TA+HYAA G F+ + L A+ A +V D +P+HYAAA G+A CC+FL QRGCNPK+KN G IAK++G K ++E+ ER G GK + E WAL LYDW+ E+ E+ + VN F+ +L +LKAP++ + ++ DK K+G + ADF+ G YV K L+ + KK K++KGGKG +K K P I ++P + R +GGPP+ I K D RF S++PP + I +D WY+ +PD +V++N ++GDL+++ LA +G VD +D F++T +++A G+L++ +L++ GADVN D F WTP+HHAAH+G ++IVELL+ GA V+A++L+G TPL RAIE + V FL+K GA + +EN KG L +A ++ +S +I+I+KA++ +LP + SG G ++ P ++ ++++ + +L S S + I DI+F + + P LL RR ++D D Y H+ + E K L
Sbjct: 9 RLQTLQIYRLLQHVRNRNKEEIEKMLKFGVANLINLRDPENGLVALHLAASADNLDLVDFLLSRGAHPDVQDKGGHTPVMLAAELGSVDIVTRLSHSQANMRIVDSAGKGVLFYCISPKKSHACCLQVALENQADVNNVSSEGVHVFQLMCEKALVCTPICLMMVDAGADPNAKDTKTGVTALMEAAKAGSLQLVRAILKRGGTPEALDKRRCTAMHYAAMGGFFEVIQVLSAYSAPMNVIDLDVCSPLHYAAASGNADCCRFLAQRGCNPKLKNLKGSTPSQIAKERGHKAAVQELKTAERKQGN-GKASKGGQAPTELWALTLYDWSHEHEAELRQAF------GDETVNLHTFMSVLTKLKAPVSPDSLHAVISAHDKKKEGLINTADFIKGVNYVKKDVLLPSRVPKKGKEEKGGKGGKKKGKCTPPFPIFILPLEKMPRRPNGGPPLFMIEKYHSRWDSRRFDSKHPPEHPIMNDSMWYMDNPDTEYVDINVCVENGDLETMDLAFSQGVPVDVQDTFFRTPMITACDSGSLEVVQYLLSKGADVNRGDQFFWTPIHHAAHAGHVEIVELLVKAGADVNAQSLDGGTPLVRAIECGQSLCVHFLVKAGANVYLENKKGQNSLRVAQDFGNSTIIDIVKARMRSLP----------KSSGSMEDPGVKSQRPKPVKKKAVAAEHAAHTDTVTTMSGSKIVQLDLRSVSLQNARIRSMEANPVDITFQAKTVWGEPPTTSQLLSNIQRRRTPVTVDVDLEDLLMPYGQSIHRKIVELSKMKDL 777
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Match: ENSORLT00000038944.1 (tankyrase-1 [Source:NCBI gene;Acc:101158122]) HSP 1 Score: 102.449 bits (254), Expect = 1.220e-21 Identity = 165/666 (24.77%), Postives = 252/666 (37.84%), Query Frame = 3
Query: 294 LSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADP------------------------------NIIQKA-----------------------TGKTPLMAACAS---GSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERS--------FGKLGKNNEPWALGLYDWTVENMT-EIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLT---GKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALP 2078
L A S N+ + L L + D + + +AA Y V + L + GAD+ D G L+ S H E E L++ +N + T L A K E+C +LL HGADP +++Q A T +T L A AS + L+ G + N ++ T +H AA+ + + L+ GA+ + D +H AA AGH C+ L G + + + G F ++ + + E + V S K G + +L T +N+ +E L + N+ V+ L+ A ++ + + ++P + G ++ A+ L V L+ + K K EIC + H P T NR N P + ++D I D R + DAAK G L ++ L ++ RD + T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G TPLDLA D R + I DALP
Sbjct: 287 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACS--YGHYEVTELLLKHGACVNAMDLWQFTPLHEAAS--KNRVEVCSLLLSHGADPTLLNCHSKSSVDMAPTPELKERLTYEFKGHSLLQAAREADMAKAKKTLALEIINFKHPHTHETALHCAVASPHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDIMEVLQKHGAKVNALDTLGQTALHRAALAGHLQTCRLLLGYGADASLVSLQG-FTAAQMGNEAVQQILNESVPVRNSDVDYRLLEAAKAGDLDTIKSL----CTPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGK-------------YEICKLLLKHGADP----------------TKKNR--DGNTPLDLVKDG-DTDIQDLLRGDAALLDAAKKGCLARVQ-KLCSPDNINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTPLDLA-TADDIRALLIDAMPPDALP 909 HSP 2 Score: 85.1149 bits (209), Expect = 2.202e-16 Identity = 57/159 (35.85%), Postives = 87/159 (54.72%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVK 2087
+AAK GDLD+IK +L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G TPLDL + D+ + ++++ L K
Sbjct: 603 EAAKAGDLDTIK-SLCTPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKD-GDTDIQDLLRGDAALLDAAK 759 HSP 3 Score: 68.1662 bits (165), Expect = 3.606e-11 Identity = 47/142 (33.10%), Postives = 75/142 (52.82%), Query Frame = 3
Query: 1599 TFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
F + +A ++GD+ +K L V+ +D + T L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL A + +V LL+ GA + N+ G + LDLA
Sbjct: 129 AFRELFEACRNGDVSRVK-KLVDAMNVNAKDMAGRKSTPLHFAAGFGRKDVVDHLLQMGANVHARDDGGLIPLHNACSFGHSEVVSLLLCQGAEPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 269 HSP 4 Score: 63.5438 bits (153), Expect = 1.095e-9 Identity = 75/297 (25.25%), Postives = 120/297 (40.40%), Query Frame = 3
Query: 162 LEILQIR------KVLQCTYEKDYDQIKKLVDNGVEHLINYNEPD-NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKD 1016
LEI+ + L C + + K++ + + N NE + + T L +A D ++ L GA + +D G++A+ AA GH+ + L GAD L L G + + E ++ L +V + N D + L A + G L +K P + + TPL A S+ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + KD
Sbjct: 458 LEIINFKHPHTHETALHCAVASPHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHNDIMEVLQKHGAKVNALDTLGQTALHRAALAGHLQTCRLLLGYGADASLVSLQG-------FTAAQMGNEAVQQILNESVPVRNSDVDYR--LLEAAKAGD------LDTIKSLCTPQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKD 739 HSP 5 Score: 59.3066 bits (142), Expect = 1.714e-8 Identity = 47/154 (30.52%), Postives = 78/154 (50.65%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGA-----VVDAK-ALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSR 2039
R ++ AA G D + L+ G V RD L +A +G+ ++ L+ GA+ NA+DN+++TPLH AA G ID+ +L+ +GA D K AL+ A P +A+ + + E L + + + LTPL++ + +D R
Sbjct: 162 RKSTPLHFAAGFGRKDVVDHLLQMGANVHARDDGGLIPLHNACSFGHSEVVSLLLCQGAEPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLAEPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 315
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Match: tnksb (tankyrase-1-like [Source:NCBI gene;Acc:105353570]) HSP 1 Score: 97.8265 bits (242), Expect = 2.769e-20 Identity = 165/666 (24.77%), Postives = 253/666 (37.99%), Query Frame = 3
Query: 294 LSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADP------------------------------NIIQKA-----------------------TGKTPLMAACAS---GSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLEN--------SGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLT---GKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIEICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPP 2081
L A S N+ + L L + D + + +AA Y V + L + GAD+ D G L+ S H E E L++ +N + T L A K E+C +LL HGADP +++Q A T +T L A AS + L+ G + N ++ T +H +A+ + L L+ GA+ + D +H AA AGH CK L G + + + G F ++ + + E + S + E G D TV+ + + + DLE + N+ V+ L+ A ++ + + ++P + G ++ A+ L V L+ + K K EIC + H P T NR N P + ++D I D R + DAAK G L ++ L ++ RD + T L AA Y NL++ +L+ +GADVNA+D PLH+AA G +DI LLI V+A TPL A + R + LL GA M+N +G T LDLA AD +I +DA+PP
Sbjct: 270 LEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACS--YGHYEVTELLLKHGACVNAMDLWQFTPLHEAAS--KNRMEVCSLLLSHGADPTLLNCHSKSAVDMAPTPELKERLTYEFKGHSLLQAAREADIAKVKKTLALEVIGFKHPQTNETALHCAVASPHPKRKQVTELLLRKGANINEKNKDFMTPLHISAERAHNDVLEVLQKHGAKVNAVDTLGQTALHRAALAGHIQTCKLLLSFGADAAIVSLQG-FTAAQMGNEAVQQILNENVPTRNSDVDY-RFLEAAKAGDLD-TVQQLC-TPQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGK-------------YEICKLLLKHGADP----------------TKKNR--DGNIPLDMVKDG-DTDIQDLLRGDAALLDAAKKGCLARVQ-KLCSQENINCRDAQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLA--TAD----DIRALLMDAMPP 888 HSP 2 Score: 79.7221 bits (195), Expect = 1.214e-14 Identity = 56/169 (33.14%), Postives = 89/169 (52.66%), Query Frame = 3
Query: 1587 DPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRD--RFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVK 2087
D D F+ +AAK GDLD+++ L V+ RD + T L AA Y + + +L+++GADV+AKD PLH+A G ++ ELL+ +GA V+ L TPL A ++ + + LLK GA +N G PLD+ + D+ + ++++ L K
Sbjct: 579 DVDYRFL---EAAKAGDLDTVQ-QLCTPQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNIPLDMVKD-GDTDIQDLLRGDAALLDAAK 742 HSP 3 Score: 65.4698 bits (158), Expect = 2.755e-10 Identity = 45/136 (33.09%), Postives = 73/136 (53.68%), Query Frame = 3
Query: 1617 DAAKHGDLDSIKLALKKGYKVDTRDRFYK--TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
+A ++GD+ +K L V+ +D + T L AA +G D+ HL+ GA+V+A+D+ PLH+A G ++V LL+ GA +A+ TPL + + +V LL+ GA + N+ G + LDLA
Sbjct: 118 EACRNGDVSRVK-RLVDTVNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQTGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHESAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 252 HSP 4 Score: 64.6994 bits (156), Expect = 4.358e-10 Identity = 69/283 (24.38%), Postives = 114/283 (40.28%), Query Frame = 3
Query: 186 VLQCTYEKDYDQIKKLVDNGVEHLINYNEPD-NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQ----KATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKD 1016
L C + + K++ + + N NE + + T L I+ D ++ L GA + VD G++A+ AA GH+ + + L GAD + L G + + E ++ L NV N D + + D +++C P + + TPL A ++ L G D + D+ G +H A G+++ L GA +V D + P+H AAA G CK L + G +P KN +G + KD
Sbjct: 455 ALHCAVASPHPKRKQVTELLLRKGANINEKNKDFMTPLHISAERAHNDVLEVLQKHGAKVNAVDTLGQTALHRAALAGHIQTCKLLLSFGADAAIVSLQG-------FTAAQMGNEAVQQILNENVPTRNSDVDYRFLEAAKAGDLDTVQQLC--------TPQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNIPLDMVKD 722 HSP 5 Score: 64.3142 bits (155), Expect = 6.440e-10 Identity = 86/323 (26.63%), Postives = 118/323 (36.53%), Query Frame = 3
Query: 228 KLVDNGVEHLINYNEPDNGKTC---LSIATSENDLDTIKFLLDLGAHPDVV---DFEGK--SAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADP-------NI---------------------------------IQK-----------ATGK--TPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIA 1010
++ + V+ ++N N P A DLDT++ L P V D EG+ + + AA Y VA E L GAD+ D G L+ S H E E +R+ +N T L A GK EIC +LLKHGADP NI +QK A G+ TPL A + + L+ G D N D+ G +H AA G+ L + + D P+H AA G C L G +P +KN G+ A +A
Sbjct: 559 QMGNEAVQQILNENVPTRNSDVDYRFLEAAKAGDLDTVQQLCT----PQNVNCRDLEGRHSTPLHFAAGYNRVAVVEYLLHHGADVHAKDKGGLVPLHNACS--YGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKY--EICKLLLKHGADPTKKNRDGNIPLDMVKDGDTDIQDLLRGDAALLDAAKKGCLARVQKLCSQENINCRDAQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTALDLA 873 HSP 6 Score: 58.9214 bits (141), Expect = 2.220e-8 Identity = 47/155 (30.32%), Postives = 79/155 (50.97%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKG-------LTPLDLAYNWADSR 2039
R ++ AA G D ++ L+ G V RD L +A +G+ ++ L+ GAD NA+DN+++TPLH +A G ID+ +L+ +GA + + +G + L A +SS V+ KK ++ S LTPL++ + +D R
Sbjct: 145 RKSTPLHFAAGFGRKDVVEHLLQTGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHESAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA-DSSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR 298 HSP 7 Score: 56.9954 bits (136), Expect = 1.058e-7 Identity = 49/193 (25.39%), Postives = 74/193 (38.34%), Query Frame = 3
Query: 1593 DRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKD------------------------------------------------NFHWT------PLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPL 2009
D + +++A G + + L L +G + RD + T L +A G +D+C+ L+ +GAD N ++ N H + PLH AA + IV+LL+ +GA V AK G PL A + V E LLK GA + + TPL
Sbjct: 177 DGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHESAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADSSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPL 369 HSP 8 Score: 51.2174 bits (121), Expect = 5.466e-6 Identity = 74/306 (24.18%), Postives = 111/306 (36.27%), Query Frame = 3
Query: 177 IRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNG---KTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE------------------NEEICLILLK------HGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIA 1010
+R++ + D ++K+LVD +N N D T L A D ++ LL GA+ D G + A +GH L GAD D L+ S + + L++ D N + DGK+ L A K NEE + LL H +D TPL A I L+ G D + D+ G +H A G+++ L GA + D Q P+H AA+ C L G +P + N + + A +A
Sbjct: 113 LRELFEACRNGDVSRVKRLVDT-----VNVNAKDMAGRKSTPLHFAAGFGRKDVVEHLLQTGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHE--SAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADSSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASD------GRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRMEVCSLLLSHGADPTLLNCHSKSAVDMA 405
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Match: ankrd44 (ankyrin repeat domain 44 [Source:NCBI gene;Acc:101173198]) HSP 1 Score: 95.9005 bits (237), Expect = 1.077e-19 Identity = 156/653 (23.89%), Postives = 263/653 (40.28%), Query Frame = 3
Query: 216 DQIKKLVDNGVEHLINYNEPDN-GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCV-SPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADR------HGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFART---IAKDKGAKDCMK---------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIE-----KKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIE-ICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEI---EDDCSWYIGDPDRTFVN----------MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLI---NNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
D +KL+ +G + + PD+ G+TCL A + ++D ++ LL G + D G++ + AA H E+L G D+ D G++ L+Y S +R R V L S+ + E KE + LL+ GA + K G +P+ A A G CL+L +D + + + ++ +H AA G+ ++L L G + D D P+ AA GHA C L +G +P +++ + RT +A G C++ EV+ V G+ P L + V+ ++ ++E N +KK + L + L +E ++ L Q D A ++++L ++ E K G G P+ C + DG V+ + D N F+ P H + + C+ + D + + ++ AA G + I+L L VD D +T LM+AA G + L++ GA ++ D TPLH A +G D V +++ ++ +++A TPL A + V+ LL +GA Q + GLTP A A SR +
Sbjct: 336 DCCRKLLSSGFQ----IDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDR---------RRRVALEPDSEGVQA------EKEKEAAQCLEFLLQSGAAAALKDK-QGYSPVHYAAAFGH----RHCLELLLDTHDGRQEEADCGNAQSPLHLAAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPL--STDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGR-----TPLMLAVVGGHVDAVSLLLEREA-----NVNTADKKGLMALHLALLCAQDECVQCLLEQDACLLQGDSQGRTPIHLAAAQGHASWLSELLTIACSESSSVPPLKDGSGY-----TPLHWACFYGQ-------DGCVEVLLEQRGCRCIDGNPFT---PLHCAVVNGHESCAALLLDAMGSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDATLINATNAAMQTPLHMAAQRGLKKAVQELLSRGASTQTVDEDGLTP---ALACAPSRQV 934 HSP 2 Score: 77.411 bits (189), Expect = 4.874e-14 Identity = 54/152 (35.53%), Postives = 80/152 (52.63%), Query Frame = 3
Query: 1590 PDRTFVNMND---------AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
P T VN++D AA +G + + L L KG ++ D+ AL AA G+LD+ L+++GA+V+ KD +TPLH AA SG I +V+ L++ +D G T L A + + VV L+ GA + N+KG TPL A
Sbjct: 78 PLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFA 229 HSP 3 Score: 76.2554 bits (186), Expect = 1.077e-13 Identity = 49/155 (31.61%), Postives = 81/155 (52.26%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHS--GMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
R + ++ AA G + +K L ++D + F TAL A G + LI+YGA+V+ +N +TPLH AA S G + +E L+NNGA ++ ++ +G +PL RF + L++ G +I + G TPL +A + +IN +
Sbjct: 155 RGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGAL-CLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTL 308 HSP 4 Score: 71.633 bits (174), Expect = 2.752e-12 Identity = 53/165 (32.12%), Postives = 82/165 (49.70%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHW-TPLHHAAHSGMIDIVELLIN--NGA-VVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGR 2102
AA HG ++++ L+ G +VD RD+ +T L AA G+ D L++ GA + D + TP+H A +G V LL++ +GA V+D G TPL A+ + V LL++ A + + KGL L LA A + + + DA D +GR
Sbjct: 519 AAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLLLEREANVNTADKKGLMALHLALLCAQDECVQCLLEQ-DACLLQGDSQGR 682 HSP 5 Score: 70.8626 bits (172), Expect = 4.789e-12 Identity = 49/128 (38.28%), Postives = 69/128 (53.91%), Query Frame = 3
Query: 1674 KVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA-YNWADSRVINII 2054
V+ DR +TAL AA G+ +M L+ GA++NA D LH AA G +D+V +L+++GA V K G TPL A S + VV+ LL +I N+ G T L LA +N D+ V +I
Sbjct: 82 SVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELI 209 HSP 6 Score: 67.781 bits (164), Expect = 4.987e-11 Identity = 79/326 (24.23%), Postives = 132/326 (40.49%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDN-GKTCLSIAT-SENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG------------------------HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVE---RSFGKLGKNNEPWALGLY 1112
+ +L+D G N ++P+N G T L A S + ++FL++ GA ++ +GKS + + A +G ++L + G ++ D +G L+ V+ H+ + T + D G L A + + + C LL G + + G+T L AA A G+ LK G + N D+ G+T +HYAA S ++ L L G + D + +HYAAA A C +FL Q G +K+ G A G + C++ ++ + G P L Y
Sbjct: 205 VSELIDYGA----NVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLH--VAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNA--HSDCCRKLLSSGFQIDT-PDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELLLDTHDGRQEEADCGNAQSPLHLAAY 521 HSP 7 Score: 62.3882 bits (150), Expect = 1.893e-9 Identity = 46/160 (28.75%), Postives = 77/160 (48.12%), Query Frame = 3
Query: 1578 YIGDPDRTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIK 2057
+ GDP+ + + + LD++++ ++ V+ RD+ ++T L AA L +I VN D T LHHAA +G ++V LL+ GA ++A L A +VV L+ GA++ ++ +G TPL A A S I ++K
Sbjct: 17 FSGDPEEIRMLIYKSEDINVLDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAA---ASSGQIAVVK 173 HSP 8 Score: 62.3882 bits (150), Expect = 2.302e-9 Identity = 74/300 (24.67%), Postives = 120/300 (40.00%), Query Frame = 3
Query: 255 LINYNEPD-NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKE-------------------------------NEEICL-ILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
L + N D G+T L A + + LL GA+ + D + A+ AA GH+ L GA++ D G L+ S + ++ L +V+++ + G T L AC +G++ + +CL L+ +GAD NI Q GK+PL G + ++ G + N+ D+ G T +H AA+ G+ + L GA P+H AA H+ CC+ L G +S G A G DC++ ++K
Sbjct: 80 LTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQ--IAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINI-QSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLK 376 HSP 9 Score: 58.5362 bits (140), Expect = 2.834e-8 Identity = 56/228 (24.56%), Postives = 104/228 (45.61%), Query Frame = 3
Query: 315 NDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGH--ASCCKFLGQRGCNPKVKNSNGE 992
N LD ++ L+ A + D ++ + +AA + E + + ++D G+ L++ + H E + L ++N K L A G + ++ +L+ HGA+ + K G TPL AA +SG ++ L L V+ + + G TA+H A +G + L +GA ++ P+H+AAA A C +FL G + +++ +G+
Sbjct: 35 NVLDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHH--AALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMG--HLDVVSVLVSHGAEVSCKDK-RGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINIQSRDGK 257 HSP 10 Score: 57.7658 bits (138), Expect = 5.792e-8 Identity = 43/168 (25.60%), Postives = 71/168 (42.26%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAI-----------------------ESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA + D + L G+++DT D +T L +AA GN+D L+ G + N D TPLH+AA S +E L+ G ++A G + L A E +EFLL+ GA +++ +G +P+ A + + ++
Sbjct: 329 AALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELL 496 HSP 11 Score: 55.8398 bits (133), Expect = 2.005e-7 Identity = 36/104 (34.62%), Postives = 56/104 (53.85%), Query Frame = 3
Query: 1767 GADVNA-KDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAY-NWADSRVINIIKAKVDA 2072
G+D+ +D TPLH AA +G + ++LL+++ A VD +G TPL A R +E LL GA + + + G TPL +A N + V+ I++ DA
Sbjct: 775 GSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDA 878 HSP 12 Score: 53.5286 bits (127), Expect = 1.071e-6 Identity = 47/174 (27.01%), Postives = 74/174 (42.53%), Query Frame = 3
Query: 645 ILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALG---LYDWTVENMTEIVEEL 1154
+L++H AD N K +TPL A A+ + + L N +DR G+TA+H+AA +G+ + + L A GA + +D +H+AA GH L G K+ G A G +K ++ + +EP A G L+ +V EL
Sbjct: 42 VLIRHSADVNARDK-NWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEI------DEPNAFGNTALHLACFNGQDAVVSEL 208 HSP 13 Score: 51.9878 bits (123), Expect = 3.347e-6 Identity = 39/132 (29.55%), Postives = 59/132 (44.70%), Query Frame = 3
Query: 1623 AKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
A HG + ++ G ++++ D+ T L AA YG+ + LI GAD + PLH AA + D L+++G +D G T L A + V+ LLK G + + G TPL A
Sbjct: 264 AVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYA 395
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Match: ankrd44 (ankyrin repeat domain 44 [Source:NCBI gene;Acc:101173198]) HSP 1 Score: 95.5153 bits (236), Expect = 1.173e-19 Identity = 155/654 (23.70%), Postives = 262/654 (40.06%), Query Frame = 3
Query: 216 DQIKKLVDNGVEHLINYNEPDN-GKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPT--ERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADR------HGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFART---IAKDKGAKDCMK---------EVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIE-----KKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFEXXXXXXXXXXXXXXXXXXIPIE-ICVMPESHIMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEI---EDDCSWYIGDPDRTFVN----------MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLI---NNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVI 2045
D +KL+ +G + + PD+ G+TCL A + ++D ++ LL G + D G++ + AA H E+L G D+ D G++ L+Y + R + LE D + V E KE + LL+ GA + K G +P+ A A G CL+L +D + + + ++ +H AA G+ ++L L G + D D P+ AA GHA C L +G +P +++ + RT +A G C++ EV+ V G+ P L + V+ ++ ++E N +KK + L + L +E ++ L Q D A ++++L ++ E K G G P+ C + DG V+ + D N F+ P H + + C+ + D + + ++ AA G + I+L L VD D +T LM+AA G + L++ GA ++ D TPLH A +G D V +++ ++ +++A TPL A + V+ LL +GA Q + GLTP A A SR +
Sbjct: 386 DCCRKLLSSGFQ----IDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALE-------------PDSEGV---QAEKEKEAAQCLEFLLQSGAAAALKDK-QGYSPVHYAAAFGH----RHCLELLLDTHDGRQEEADCGNAQSPLHLAAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPL--STDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGR-----TPLMLAVVGGHVDAVSLLLEREA-----NVNTADKKGLMALHLALLCAQDECVQCLLEQDACLLQGDSQGRTPIHLAAAQGHASWLSELLTIACSESSSVPPLKDGSGY-----TPLHWACFYGQ-------DGCVEVLLEQRGCRCIDGNPFT---PLHCAVVNGHESCAALLLDAMGSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDATLINATNAAMQTPLHMAAQRGLKKAVQELLSRGASTQTVDEDGLTP---ALACAPSRQV 984 HSP 2 Score: 77.411 bits (189), Expect = 5.436e-14 Identity = 54/152 (35.53%), Postives = 80/152 (52.63%), Query Frame = 3
Query: 1590 PDRTFVNMND---------AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
P T VN++D AA +G + + L L KG ++ D+ AL AA G+LD+ L+++GA+V+ KD +TPLH AA SG I +V+ L++ +D G T L A + + VV L+ GA + N+KG TPL A
Sbjct: 128 PLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFA 279 HSP 3 Score: 76.2554 bits (186), Expect = 1.211e-13 Identity = 49/155 (31.61%), Postives = 81/155 (52.26%), Query Frame = 3
Query: 1596 RTFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHS--GMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
R + ++ AA G + +K L ++D + F TAL A G + LI+YGA+V+ +N +TPLH AA S G + +E L+NNGA ++ ++ +G +PL RF + L++ G +I + G TPL +A + +IN +
Sbjct: 205 RGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGAL-CLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTL 358 HSP 4 Score: 71.2478 bits (173), Expect = 3.567e-12 Identity = 53/165 (32.12%), Postives = 82/165 (49.70%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHW-TPLHHAAHSGMIDIVELLIN--NGA-VVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGR 2102
AA HG ++++ L+ G +VD RD+ +T L AA G+ D L++ GA + D + TP+H A +G V LL++ +GA V+D G TPL A+ + V LL++ A + + KGL L LA A + + + DA D +GR
Sbjct: 569 AAYHGHAQALQVLLRGGREVDERDQAGRTPLALAALRGHADCVHTLLSQGASPLSTDQLYGRTPVHLAVMNGHTTCVRLLLDEPDGAEVLDVADPQGRTPLMLAVVGGHVDAVSLLLEREANVNTADKKGLMALHLALLCAQDECVQCLLEQ-DACLLQGDSQGR 732 HSP 5 Score: 70.8626 bits (172), Expect = 5.015e-12 Identity = 49/157 (31.21%), Postives = 79/157 (50.32%), Query Frame = 3
Query: 1632 GDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGR 2102
GD + I++ + K ++ D +T L +AA G+ ++ LI GA VNAKDN +TPLH A S D V++LI + A V+A+ N TPL A ++ E ++ + + + G T L A + ++N++ AK + K GR
Sbjct: 19 GDPEEIRMLIYKSEDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGR 175 HSP 6 Score: 70.8626 bits (172), Expect = 5.461e-12 Identity = 49/128 (38.28%), Postives = 69/128 (53.91%), Query Frame = 3
Query: 1674 KVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA-YNWADSRVINII 2054
V+ DR +TAL AA G+ +M L+ GA++NA D LH AA G +D+V +L+++GA V K G TPL A S + VV+ LL +I N+ G T L LA +N D+ V +I
Sbjct: 132 SVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELI 259 HSP 7 Score: 67.781 bits (164), Expect = 4.180e-11 Identity = 79/326 (24.23%), Postives = 132/326 (40.49%), Query Frame = 3
Query: 222 IKKLVDNGVEHLINYNEPDN-GKTCLSIAT-SENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAG------------------------HASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVE---RSFGKLGKNNEPWALGLY 1112
+ +L+D G N ++P+N G T L A S + ++FL++ GA ++ +GKS + + A +G ++L + G ++ D +G L+ V+ H+ + T + D G L A + + + C LL G + + G+T L AA A G+ LK G + N D+ G+T +HYAA S ++ L L G + D + +HYAAA A C +FL Q G +K+ G A G + C++ ++ + G P L Y
Sbjct: 255 VSELIDYGA----NVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLH--VAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNA--HSDCCRKLLSSGFQIDT-PDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELLLDTHDGRQEEADCGNAQSPLHLAAY 571 HSP 8 Score: 65.855 bits (159), Expect = 1.762e-10 Identity = 73/273 (26.74%), Postives = 116/273 (42.49%), Query Frame = 3
Query: 255 LINYNEPD-NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKAT-GKTPLMAACASGSTSIPSKCLKL----GVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAA-GHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIK 1052
L + N D G+T L A + + LL GA+ + D + A+ AA GH+ L GA++ D G L+ S + ++ L +V+++ + G T L AC +G+ + + L+ +GA N+ Q G TPL A AS ++ CL+ G D N R GK+ +H A G F L G + + D N P+H AA GH L G + + +G F +A DC ++++
Sbjct: 130 LTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQ--IAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQ--DAVVSELIDYGA--NVSQPNNKGFTPLHFAAASTHGAL---CLEFLVNNGADINIQSRDGKSPLHMTAVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLS 393 HSP 9 Score: 58.5362 bits (140), Expect = 2.927e-8 Identity = 49/163 (30.06%), Postives = 75/163 (46.01%), Query Frame = 3
Query: 1611 MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKG 2099
++ AA GD + +L + G +V+ +D + T L A + D LI + ADVNA+D TPLH AA + + E++I V+ G T L A + +V LL KGA I + K L A V++++ + A KDK+G
Sbjct: 45 LHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSH-GAEVSCKDKRG 206 HSP 10 Score: 57.3806 bits (137), Expect = 6.566e-8 Identity = 57/237 (24.05%), Postives = 106/237 (44.73%), Query Frame = 3
Query: 288 TCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGH--ASCCKFLGQRGCNPKVKNSNGE 992
T L A + D ++ L+ A + D ++ + +AA + E + + ++D G+ L++ + H E + L ++N K L A G + ++ +L+ HGA+ + K G TPL AA +SG ++ L L V+ + + G TA+H A +G + L +GA ++ P+H+AAA A C +FL G + +++ +G+
Sbjct: 76 TPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHH--AALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMG--HLDVVSVLVSHGAEVSCKDK-RGYTPLHAAASSGQIAVVKHLLSLSVEIDEPNAFGNTALHLACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNNGADINIQSRDGK 307 HSP 11 Score: 57.3806 bits (137), Expect = 6.851e-8 Identity = 43/168 (25.60%), Postives = 71/168 (42.26%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAI-----------------------ESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA + D + L G+++DT D +T L +AA GN+D L+ G + N D TPLH+AA S +E L+ G ++A G + L A E +EFLL+ GA +++ +G +P+ A + + ++
Sbjct: 379 AALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYAAASRHYHCLETLVVCGTDINATDQWGRSALHYAAASDLDRRRRVALEPDSEGVQAEKEKEAAQCLEFLLQSGAAAALKDKQGYSPVHYAAAFGHRHCLELL 546 HSP 12 Score: 57.3806 bits (137), Expect = 7.523e-8 Identity = 45/134 (33.58%), Postives = 66/134 (49.25%), Query Frame = 3
Query: 1701 KTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGR 2102
+ AL+ A G+ + LI D+N D TPLH AA G +I ELLI +GA V+AK TPL RA+ S + V+ L++ A + + TPL +A R +I + ++ V D+ GR
Sbjct: 9 QPALIQAIFSGDPEEIRMLIYKSEDINVLDAEKRTPLHAAAFLGDAEITELLILSGARVNAKDNMWFTPLHRAVASRSQDAVQVLIRHSADVNARDKNWQTPLHVAAANNALRCAEVIIPLLTSV-NVSDRGGR 141 HSP 13 Score: 55.4546 bits (132), Expect = 2.432e-7 Identity = 36/104 (34.62%), Postives = 56/104 (53.85%), Query Frame = 3
Query: 1767 GADVNA-KDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA-YNWADSRVINIIKAKVDA 2072
G+D+ +D TPLH AA +G + ++LL+++ A VD +G TPL A R +E LL GA + + + G TPL +A N + V+ I++ DA
Sbjct: 825 GSDITGCRDAKGRTPLHAAAFAGQTECIQLLLSHDAPVDPADDHGRTPLMTAAAKGRVGALEALLDAGAGLSLIDRDGNTPLHVACSNGTEDGVLMILQRLSDA 928 HSP 14 Score: 53.5286 bits (127), Expect = 1.023e-6 Identity = 47/174 (27.01%), Postives = 74/174 (42.53%), Query Frame = 3
Query: 645 ILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALG---LYDWTVENMTEIVEEL 1154
+L++H AD N K +TPL A A+ + + L N +DR G+TA+H+AA +G+ + + L A GA + +D +H+AA GH L G K+ G A G +K ++ + +EP A G L+ +V EL
Sbjct: 92 VLIRHSADVNARDK-NWQTPLHVAAANNALRCAEVIIPLLTSVNVSDRGGRTALHHAALNGHTEMVNLLLAKGANINAFDKKDGRALHWAAFMGHLDVVSVLVSHGAEVSCKDKRGYTPLHAAASSGQIAVVKHLLSLSVEI------DEPNAFGNTALHLACFNGQDAVVSEL 258 HSP 15 Score: 51.6026 bits (122), Expect = 3.690e-6 Identity = 39/132 (29.55%), Postives = 59/132 (44.70%), Query Frame = 3
Query: 1623 AKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
A HG + ++ G ++++ D+ T L AA YG+ + LI GAD + PLH AA + D L+++G +D G T L A + V+ LLK G + + G TPL A
Sbjct: 314 AVHGRFTRSQTLIQNGGEINSVDKDGNTPLHVAARYGHELLINTLITSGADCARRGVHGMFPLHLAALNAHSDCCRKLLSSGFQIDTPDSLGRTCLHAAAAGGNVDCVQLLLKSGGEHNRTDKCGRTPLHYA 445
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006938.1 (SMESG000006938.1) HSP 1 Score: 837.025 bits (2161), Expect = 0.000e+0 Identity = 405/407 (99.51%), Postives = 405/407 (99.51%), Query Frame = 3
Query: 141 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE 1361
MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLE ALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWAL LYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE
Sbjct: 1 MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLEIALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALALYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE 407
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006940.1 (SMESG000006940.1) HSP 1 Score: 479.174 bits (1232), Expect = 3.879e-164 Identity = 243/244 (99.59%), Postives = 243/244 (99.59%), Query Frame = 3
Query: 1713 MSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
MSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKPVEQPPEPPQRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPD FQSYFHKNLTERVKASGLED
Sbjct: 1 MSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKPVEQPPEPPQRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDVFQSYFHKNLTERVKASGLED 244
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006940.1 (SMESG000006940.1) HSP 1 Score: 389.037 bits (998), Expect = 6.641e-130 Identity = 203/204 (99.51%), Postives = 203/204 (99.51%), Query Frame = 3
Query: 1833 MIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKXXXXXXXXXXRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDEFQSYFHKNLTERVKASGLED 2444
MIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKPVEQPPEPPQRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPD FQSYFHKNLTERVKASGLED
Sbjct: 1 MIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAKVDALPPVKDKKGRGNQKSGRTSSKGRRTASPTKPVEQPPEPPQRSYSELALKRANNLLSYSSKPEDIEDISFTPRYLLVNRPHLESLLQIRHERRQRFGWEIDFPDVFQSYFHKNLTERVKASGLED 204
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000006933.1 (SMESG000006933.1) HSP 1 Score: 334.724 bits (857), Expect = 2.884e-109 Identity = 173/218 (79.36%), Postives = 173/218 (79.36%), Query Frame = 3
Query: 708 MAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE 1361
MAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKS GCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWAL LYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE
Sbjct: 1 MAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKS--------------------------------------------GCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALALYDWTVENMTEIVEELKLLDLENSGIVNKKEFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFLTGKKYVNKLYLMSAFE 174
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Match: SMESG000026655.1 (SMESG000026655.1) HSP 1 Score: 94.3597 bits (233), Expect = 2.555e-19 Identity = 146/651 (22.43%), Postives = 272/651 (41.78%), Query Frame = 3
Query: 279 NGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKH----------------------------GADPNI-IQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA-AGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKGAKDCMKEVIKVERSFGKLGKNNEPWALGLYDWTVENMTEIVEELKLLD--LENSGIVNKK-----------------EFVDLLIRLKAPLNEEIEKKILPQFDKNKDGTFDYADFL---------TGKKYVNKLYLMS------AFEXXXXXXXXXXXXXXXXXXIPIEICVMPESH--IMRPIDGGPPVMYIPKEQYSTDLNRFSSENPPHNEIEDDCSWYIGDPD----RTFVNMNDAAKHGDLD-SIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
NG + +A E + + ++ L++ G D+ +G +++ IA+ G + L ++ A++ + NG LY ++ E H + ++ L Y + + DG T L A + G N+++ ILL + +D N+ Q A+G TPL A + ++ ++ D N ++ T +H AAK G + L L + A + +PIH AA +G + L + G + + K+ NG A +A + + +I K + A+ + T ++ + + L+N+ VN + + V+LLI+ KA +N E + P G+ + + L T K N L+L + F+ + ++R+++ P+ I V ++ + + ++ G + K+ Y T L+ + E +EI + PD + F ++ A+K+G + + +L L ++ T L A +Y + +M L++ A+VN +TPLH A MI++ +LLI+ GA V+A++ G TPL + ++E LL A + + GLT L LA
Sbjct: 124 NGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLY--MAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQG--NDKVVQILLDNDSRSKVRLPALHIAAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNITPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLI---------NKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNY-TALHIAAKEG--RHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLA 758 HSP 2 Score: 87.8113 bits (216), Expect = 3.060e-17 Identity = 53/145 (36.55%), Postives = 77/145 (53.10%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ G + I + L+ G + + + TAL A ++C LIN G DV+A + T LH AAH G I+ E+L+ N V+A+ALNG TPL A + + +VE L+K A I GLTPL +A ++NI+
Sbjct: 360 AARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELLIKYKAHINSTTETGLTPLHIAAFMGSKEIVNIL 504 HSP 3 Score: 75.485 bits (184), Expect = 1.500e-13 Identity = 45/145 (31.03%), Postives = 78/145 (53.79%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA+ G+++ +K L+ K D + A+ AA GN ++ LI G V+ T LH A+ +G +++V LL+ + A ++ K+ NG TPL+ A + + +VV+ LL+ GA + G TPL +A + +V+ I+
Sbjct: 99 AARSGNVEKVKEFLQADIKPDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQIL 243 HSP 4 Score: 69.707 bits (169), Expect = 1.059e-11 Identity = 56/158 (35.44%), Postives = 84/158 (53.16%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGY-KVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVN--AKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK---VDAL 2075
AAK D+++ L + VD + T L AAHY N+++ LI ADVN AK+N TPLH AA G ++++LLI+ A V++ +G +P+ A S N++ LL+ GA IQ ++ GLT L +A + V + K VDA+
Sbjct: 260 AAKKDDVNAASLLIGSSDDNVDHQSASGFTPLHIAAHYNNVNVAKLLIEKNADVNFPAKNNI--TPLHVAAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAV 415 HSP 5 Score: 64.6994 bits (156), Expect = 2.988e-10 Identity = 69/279 (24.73%), Postives = 116/279 (41.58%), Query Frame = 3
Query: 189 LQCTYEKDYDQIKK-LVDNG--VEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGA--------------------------------DPNIIQKA-TGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQNNPIHYAA 917
+ C ++ I L++NG ++H + NG T L +AT + + + L++ G D V + +A+ +AA G++ + E L K ++ LNG L+ + + +E ++Y +N+ ++ G T L A G ++EI ILLK+GA + N +A +TPL A G+ SI + L G DPN + TA+H AAK G + L + D P+H A+
Sbjct: 357 IHCAARSGFENIILILLENGADIQH-----KSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQ--SKMVELLIKYKAHINSTTETGLTPLHIAAFMG--SKEIVNILLKNGASISQTTMKCENALHLAARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIAS 626 HSP 6 Score: 64.6994 bits (156), Expect = 3.540e-10 Identity = 41/120 (34.17%), Postives = 66/120 (55.00%), Query Frame = 3
Query: 1704 TALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINIIKAK 2063
T L A +++ LI+ GA+VNA+ +TPLH + +G +I+ELL++ A V+ +A NG T L A E +R ++VE LLK A I + G T L A ++ + + ++ K
Sbjct: 687 TPLHLVAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEK 806 HSP 7 Score: 63.929 bits (154), Expect = 6.038e-10 Identity = 41/127 (32.28%), Postives = 67/127 (52.76%), Query Frame = 3
Query: 1590 PDRTFVN----MNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLL 1958
PD + N M+ AAK G+ + ++L ++ G VD R T+L A+ G L++ L+ A++N K +TPL+ AA +D+V++L+ GA +G TPL A++ VV+ LL
Sbjct: 118 PDMSNANGLNAMHLAAKEGNREVVQLLIENGLSVDIATRKGNTSLHIASLAGKLEVVSLLLESKANINVKSQNGFTPLYMAAQENHLDVVKVLLEYGANQAITTDDGFTPLAVALQQGNDKVVQILL 244 HSP 8 Score: 61.2326 bits (147), Expect = 3.828e-9 Identity = 39/114 (34.21%), Postives = 56/114 (49.12%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLK 1961
AA+ D ++ LK + T+ + TAL +A H+G + L+ DVNA+ N T LH AA G I IV LL++N V+ + G T L A + N+ E L K
Sbjct: 758 AAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVAQKQHYLNIAETLSK 871 HSP 9 Score: 59.3066 bits (142), Expect = 1.399e-8 Identity = 40/145 (27.59%), Postives = 65/145 (44.83%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AAK G + +KL + + V++ R + + AA G ++ + L+ GAD+ K T L A ++ + LIN G VDA ++ T L A N E LLK + G TPL +A S+++ ++
Sbjct: 327 AAKWGKEEMLKLLISQKANVNSVTRDGLSPIHCAARSGFENIILILLENGADIQHKSKNGLTALQMATQGDQAEVCQTLINKGIDVDAVTMDYLTALHVAAHCGNINAAEVLLKNNCNVNARALNGFTPLHIACKKIQSKMVELL 471 HSP 10 Score: 59.3066 bits (142), Expect = 1.472e-8 Identity = 41/140 (29.29%), Postives = 67/140 (47.86%), Query Frame = 3
Query: 1599 TFVNMNDAAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLA 2018
T +++N A G+ + ++L L V+ + TAL AA D+ L+ AD++ K +T LH A H G I V++L+ V+A+ G T L A + +V LL + +N +GLT L++A
Sbjct: 720 TPLHLNSMA--GNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLLLDNEIDVNHQNKQGLTALEVA 857 HSP 11 Score: 56.6102 bits (135), Expect = 9.092e-8 Identity = 40/145 (27.59%), Postives = 66/145 (45.52%), Query Frame = 3
Query: 1620 AAKHGDLDSIKLALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVVEFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AK ++ KL + +G V+ + + T L + GN ++ L++ ADVN + T LH AA DIVE L+ A + K G T L A+ + V+ LL+K + + + G T L LA ++ ++
Sbjct: 692 VAKKNMIEVTKLLIDRGANVNAQSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKNRTDIVEQLLKTEADISTKTQMGYTALHTAVHFGQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQGHIAIVRLL 836 HSP 12 Score: 55.8398 bits (133), Expect = 1.617e-7 Identity = 46/147 (31.29%), Postives = 66/147 (44.90%), Query Frame = 3
Query: 1620 AAKHGDLDSIK-LALKKGYKVDTRDRFYKTALMSAAHYGNLDMCMHLINYGADVNAKDNFHWTPLHHAAHSGMIDIVELLINNGAVVDAKALNGATPLFRAIESSRFNVV-EFLLKKGAKIQMENSKGLTPLDLAYNWADSRVINII 2054
AA++ ++ K L L + R R +T L A GN + L+N GAD N ++T LH AA G +I LL+ + DAK G TPL A + R V + LL GLTPL +A + +I ++
Sbjct: 525 AARNNQEETFKILLLHPEANFNARARENQTPLHIAVRMGNYSIVEQLLNAGADPNMVTKDNYTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLLLSAKVNPNSLGHHGLTPLHVATYYNHYEMIELL 671 HSP 13 Score: 54.6842 bits (130), Expect = 4.139e-7 Identity = 67/277 (24.19%), Postives = 117/277 (42.24%), Query Frame = 3
Query: 210 DYDQIKKLVDNGVEHLINYNEPDNGKTCLSIATSENDLDTIKFLLDLGAHPDVVDFEGKSAIMIAAQYGHVASFESLAKAGADLKLNDLNGKNVLYYCVSPTERHKECLETALRYNVDLNNVSKDGKTVLFHACEDGKENEEICLILLKHGADPNIIQKATGKTPLMAACASGSTSIPSKCLKLGVDPNTADRHGKTAVHYAAKSGNFKSLVALRAFGAQFDVYDDTQ------NNPIHYAAAGHASCCKFLGQRGCNPKVKNSNGEFARTIAKDKG 1022
+Y +++L++ G + N DN T L IA E + + LL+ PD +G + + IA++YG V L A + N L + V+ H E +E L ++N + K+G T L + K E+ +L+ GA+ N Q G TPL +G+ I L D N +G TA+H AA+ ++ + + + D+ TQ + +H+ G K L ++ + + + G + +A +G
Sbjct: 564 NYSIVEQLLNAGADP--NMVTKDN-YTALHIAAKEGRHEISRLLLEHQCKPDAKTKKGFTPLHIASKYGRVQVARQLL-LSAKVNPNSLGHHGLTPLHVATYYNHYEMIELLLDTEANVNCLYKNGYTPLHLVAK--KNMIEVTKLLIDRGANVNA-QSQKGFTPLHLNSMAGNKEIMELLLDANADVNHQAENGLTALHLAAEKN--RTDIVEQLLKTEADISTKTQMGYTALHTAVHF---GQIQTVKMLLEKNFDVNAQTNLGCTSLHLAAQQG 828 The following BLAST results are available for this feature:
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Ankyrin repeat and EF-hand domain-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30025084 ID=SMED30025084|Name=Ankyrin repeat and EF-hand domain-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=2749bpback to top protein sequence of SMED30025084-orf-1 >SMED30025084-orf-1 ID=SMED30025084-orf-1|Name=SMED30025084-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=769bp MPIAQSRLEILQIRKVLQCTYEKDYDQIKKLVDNGVEHLINYNEPDNGKTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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