Calcium/calmodulin-dependent protein kinase type II

Overview
NameCalcium/calmodulin-dependent protein kinase type II
Smed IDSMED30025071
Length (bp)2052
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Calcium/calmodulin-dependent protein kinase type II (SMED30025071) t-SNE clustered cells

Violin plots show distribution of expression levels for Calcium/calmodulin-dependent protein kinase type II (SMED30025071) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Calcium/calmodulin-dependent protein kinase type II (SMED30025071) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Calcium/calmodulin-dependent protein kinase type II (SMED30025071) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025071

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 15

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
parapharyngeal regionSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30025071h1SMcG0014565 dd_Smed_v4_7480_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0014565 Contig42490uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0014565 Contig42490newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0014565 Contig42491newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0014565 Contig42491uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0014565 Contig2955newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30025071h1SMcG0018489 Contig2955newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30025071h1SMcG0014565 dd_Smed_v6_7480_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Match: CAMK2D (calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462])

HSP 1 Score: 703.36 bits (1814), Expect = 0.000e+0
Identity = 339/502 (67.53%), Postives = 405/502 (80.68%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS   S      + KK +G  K  + S    +E T+ S         N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKS------LLKKPDGVKKRKSSSSVQMMESTESS---------NTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 481
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Match: CAMK2D (calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462])

HSP 1 Score: 701.434 bits (1809), Expect = 0.000e+0
Identity = 339/503 (67.40%), Postives = 405/503 (80.52%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS   S      + KK +G  K  + S    +E T+ S         N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKS------LLKKPDGVKKRKSSSSVQMMESTESS---------NTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 481
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Match: CAMK2D (calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 338/502 (67.33%), Postives = 402/502 (80.08%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Match: CAMK2D (calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 338/502 (67.33%), Postives = 402/502 (80.08%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Match: CAMK2D (calcium/calmodulin dependent protein kinase II delta [Source:HGNC Symbol;Acc:HGNC:1462])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 338/502 (67.33%), Postives = 402/502 (80.08%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 327/523 (62.52%), Postives = 409/523 (78.20%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSS----------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M+  + KFSD Y++KEELG+GAFS+V+RCV K + LEFAAKIINTK+LS+RD QKLEREARICR L+HPNIVRLHDSIQ++ FHYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILES+ YCH N I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ ++E  +W GFAGTPGYLSPEVL+KDPY KPVD+WACGVILYILLVGYPPFWDEDQ+RLYAQIK+G +DYPSPEWDTVT EAK+LI+ MLTVNP KRITA +ALK PWI  RE +AS +HRQ TVDCLKKFNARRKLKGAILTTM+ATRN S    N    L++KK  G    IK+S++S +  I+D D  K   ++ + N TV+++D ++                  +  +KQ+I++VT+ L+ +IS  DF +YT+L D+++TCF PE++GNLIEG++ HRFYF+          HT++LNP VH++GE+ AC+AYV+L QF DR NG +   T Q +E+R+W K+   +W  +HVHRS
Sbjct:    1 MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSE--AWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTMIATRNLSNLGRN----LLNKKEQGPPSTIKESSES-SQTIDDNDSEKGGGQLKHEN-TVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFD---GNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDR-NGEAH--TRQSQESRVWSKK-QGRWVCVHVHRS 508
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 327/523 (62.52%), Postives = 409/523 (78.20%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSS----------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M+  + KFSD Y++KEELG+GAFS+V+RCV K + LEFAAKIINTK+LS+RD QKLEREARICR L+HPNIVRLHDSIQ++ FHYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILES+ YCH N I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ ++E  +W GFAGTPGYLSPEVL+KDPY KPVD+WACGVILYILLVGYPPFWDEDQ+RLYAQIK+G +DYPSPEWDTVT EAK+LI+ MLTVNP KRITA +ALK PWI  RE +AS +HRQ TVDCLKKFNARRKLKGAILTTM+ATRN S    N    L++KK  G    IK+S++S +  I+D D  K   ++ + N TV+++D ++                  +  +KQ+I++VT+ L+ +IS  DF +YT+L D+++TCF PE++GNLIEG++ HRFYF+          HT++LNP VH++GE+ AC+AYV+L QF DR NG +   T Q +E+R+W K+   +W  +HVHRS
Sbjct:    1 MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSE--AWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTMIATRNLSNLGRN----LLNKKEQGPPSTIKESSES-SQTIDDNDSEKGGGQLKHEN-TVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFD---GNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDR-NGEAH--TRQSQESRVWSKK-QGRWVCVHVHRS 508
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 673.7 bits (1737), Expect = 0.000e+0
Identity = 327/523 (62.52%), Postives = 409/523 (78.20%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSS----------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M+  + KFSD Y++KEELG+GAFS+V+RCV K + LEFAAKIINTK+LS+RD QKLEREARICR L+HPNIVRLHDSIQ++ FHYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILES+ YCH N I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ ++E  +W GFAGTPGYLSPEVL+KDPY KPVD+WACGVILYILLVGYPPFWDEDQ+RLYAQIK+G +DYPSPEWDTVT EAK+LI+ MLTVNP KRITA +ALK PWI  RE +AS +HRQ TVDCLKKFNARRKLKGAILTTM+ATRN S    N    L++KK  G    IK+S++S +  I+D D  K   ++ + N TV+++D ++                  +  +KQ+I++VT+ L+ +IS  DF +YT+L D+++TCF PE++GNLIEG++ HRFYF+          HT++LNP VH++GE+ AC+AYV+L QF DR NG +   T Q +E+R+W K+   +W  +HVHRS
Sbjct:    1 MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSE--AWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTMIATRNLSNLGRN----LLNKKEQGPPSTIKESSES-SQTIDDNDSEKGGGQLKHEN-TVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFD---GNRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDR-NGEAH--TRQSQESRVWSKK-QGRWVCVHVHRS 508
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 326/523 (62.33%), Postives = 409/523 (78.20%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSS----------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M+  + KFSD Y++KEELG+GAFS+V+RCV K + LEFAAKIINTK+LS+RD QKLEREARICR L+HPNIVRLHDSIQ++ FHYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILES+ YCH N I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ ++E  +W GFAGTPGYLSPEVL+KDPY KPVD+WACGVILYILLVGYPPFWDEDQ+RLYAQIK+G +DYPSPEWDTVT EAK+LI+ MLTVNP KRITA +ALK PWI  RE +AS +HRQ TVDCLKKFNARRKLKGAILTTM+ATRN S        +L++KK  G    IK+S++S +  I+D D  K   ++ + N TV+++D ++                  +  +KQ+I++VT+ L+ +IS  DF +YT+L D+++TCF PE++GNLIEG++ HRFYF+          HT++LNP VH++GE+ AC+AYV+L QF DR NG +   T Q +E+R+W K+   +W  +HVHRS
Sbjct:    1 MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSE--AWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTMIATRNLSS------RNLLNKKEQGPPSTIKESSES-SQTIDDNDSEKGGGQLKHEN-TVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDG---NRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDR-NGEAH--TRQSQESRVWSKK-QGRWVCVHVHRS 506
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Match: unc-43 (Calcium/calmodulin-dependent protein kinase type II [Source:UniProtKB/Swiss-Prot;Acc:O62305])

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 326/523 (62.33%), Postives = 409/523 (78.20%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSS----------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M+  + KFSD Y++KEELG+GAFS+V+RCV K + LEFAAKIINTK+LS+RD QKLEREARICR L+HPNIVRLHDSIQ++ FHYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILES+ YCH N I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ ++E  +W GFAGTPGYLSPEVL+KDPY KPVD+WACGVILYILLVGYPPFWDEDQ+RLYAQIK+G +DYPSPEWDTVT EAK+LI+ MLTVNP KRITA +ALK PWI  RE +AS +HRQ TVDCLKKFNARRKLKGAILTTM+ATRN S        +L++KK  G    IK+S++S +  I+D D  K   ++ + N TV+++D ++                  +  +KQ+I++VT+ L+ +IS  DF +YT+L D+++TCF PE++GNLIEG++ HRFYF+          HT++LNP VH++GE+ AC+AYV+L QF DR NG +   T Q +E+R+W K+   +W  +HVHRS
Sbjct:    1 MMNASTKFSDNYDVKEELGKGAFSVVRRCVHKTTGLEFAAKIINTKKLSARDFQKLEREARICRKLQHPNIVRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESIAYCHSNGIVHRDLKPENLLLASKAKGAAVKLADFGLAIEVNDSE--AWHGFAGTPGYLSPEVLKKDPYSKPVDIWACGVILYILLVGYPPFWDEDQHRLYAQIKAGAYDYPSPEWDTVTPEAKSLIDSMLTVNPKKRITADQALKVPWICNRERVASAIHRQDTVDCLKKFNARRKLKGAILTTMIATRNLSS------RNLLNKKEQGPPSTIKESSES-SQTIDDNDSEKGGGQLKHEN-TVVRADGATGIVSSSNSSTASKSSSTNLSAQKQDIVRVTQTLLDAISCKDFETYTRLCDTSMTCFEPEALGNLIEGIEFHRFYFDG---NRKNQVHTTMLNPNVHIIGEDAACVAYVKLTQFLDR-NGEAH--TRQSQESRVWSKK-QGRWVCVHVHRS 506
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0100147)

HSP 1 Score: 730.324 bits (1884), Expect = 0.000e+0
Identity = 349/500 (69.80%), Postives = 415/500 (83.00%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D  +     ++ ++TV    VS      ++QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTV----VSKEPEAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 492
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0089219)

HSP 1 Score: 730.324 bits (1884), Expect = 0.000e+0
Identity = 349/500 (69.80%), Postives = 415/500 (83.00%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D  +     ++ ++TV    VS      ++QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTV----VSKEPEAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 492
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0100148)

HSP 1 Score: 728.398 bits (1879), Expect = 0.000e+0
Identity = 348/503 (69.18%), Postives = 416/503 (82.70%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETK---KQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D  +     ++ ++TV+  +   +    K   +QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEVNLFTNKAARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 499
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0300378)

HSP 1 Score: 726.087 bits (1873), Expect = 0.000e+0
Identity = 350/517 (67.70%), Postives = 420/517 (81.24%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTD---------------DSKTPSRV-MNCNSTVLKSDVSSSEIET-KKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D                SK P  + + C +   + ++ +S+  + ++QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 513
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Match: CaMKII (gene:FBgn0264607 transcript:FBtr0100146)

HSP 1 Score: 726.087 bits (1873), Expect = 0.000e+0
Identity = 350/517 (67.70%), Postives = 420/517 (81.24%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTD---------------DSKTPSRV-MNCNSTVLKSDVSSSEIET-KKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D                SK P  + + C +   + ++ +S+  + ++QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 513
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Match: camk2d2 (calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2 [Source:NCBI gene;Acc:436815])

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 336/498 (67.47%), Postives = 403/498 (80.92%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            +F+D Y++ EELG+GAFS+V+RCV+ +S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESV++CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTT+L TRNFS        SL++KK + G+K+   +V     D +   T S     N+T+   D     ++ +KQEIIKVTEQLI SI+  DF +Y K+ D  LT F PE++GNL+EG D HRFYFENALSK  K  HT +LNP VHL+GE+ ACIAY+RL Q+ D   G     T Q EETR+W +R + KW NIH HRS
Sbjct:    8 RFTDEYQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTLLVTRNFSA-----AKSLLNKKPD-GVKEPQTTVIHNPVDRNKESTES----ANTTIEDED-----LKARKQEIIKVTEQLIESINNGDFEAYAKICDPGLTSFEPEALGNLVEGHDFHRFYFENALSKGNKPVHTILLNPHVHLIGEDAACIAYIRLTQYMD---GSGMPRTMQSEETRVWHRR-DGKWLNIHFHRS 485
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Match: camk2b1 (calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 [Source:ZFIN;Acc:ZDB-GENE-030131-9588])

HSP 1 Score: 687.567 bits (1773), Expect = 0.000e+0
Identity = 329/528 (62.31%), Postives = 410/528 (77.65%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS--------------------------KFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RCV+ ++  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYL+FDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK KNA VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA EALKHPW+ QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTML +RNFS                               +  +L++KK++  +K  T+S   +I  +     PS  +  +S    + V   E++ +KQEIIK+TEQLI +I+  DF +Y K+ D  LTCF PE++GNL+EG+D HRFYFEN LSKN+K  HT+ILNP VHL+GEE ACIAY+RL Q+ D   G  +  + Q EETR+W +R ++KWQN+H H S
Sbjct:    4 TTCTRFTDEYQLYEELGKGAFSVVRRCVKLSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSVGSRQTTAPASVTAAAAAVAAAAGTTAGLVEQAKTLLNKKAD--VKPQTNSTKNSIVTSPKGNLPSPALE-SSDSSNATVEDEEMKARKQEIIKITEQLIEAINNGDFEAYAKICDPGLTCFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEEAACIAYIRLTQYVD---GQGRPRSSQSEETRVWHRR-DSKWQNVHFHCS 523
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Match: camk2a (calcium/calmodulin-dependent protein kinase II alpha [Source:ZFIN;Acc:ZDB-GENE-051113-72])

HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0
Identity = 334/498 (67.07%), Postives = 402/498 (80.72%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            +F++ Y++ EELG+GAFS+V+RCV+  S  E+AAKIINTK+LS+RD QKL+REARICRLLKHPNIVRLHDSI ++G HYL+FDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SKSK A VKLADFGLA+E+ E E+ +W GFAGTPGYLSPEVLRKDPYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI  R  +AS +HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS     + G  +SKK++ G+K+S++S    IED D     +RV                   +KQEIIKVTEQLI +IS  DF SYTK+ D ++T F PE++GNL+EG+D HRFYFEN  SKN+K  HT+ILNP +HL+GEE ACIAY+R+ Q+ D  N G  C T Q EETRIW  R + KWQ +H HRS
Sbjct:    8 RFTEEYQLFEELGKGAFSVVRRCVKVLSGQEYAAKIINTKKLSTRDHQKLDREARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVECLKKFNARRKLKGAILTTMLATRNFS---GGKSG--VSKKTD-GVKESSESTNTTIEDED-----TRV-------------------RKQEIIKVTEQLIEAISNGDFESYTKMCDPSVTAFEPEALGNLVEGLDFHRFYFENLWSKNSKPVHTTILNPHIHLIGEEAACIAYIRITQYLD--NNGMPC-TAQSEETRIWH-RKDGKWQIVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Match: camk2d1 (calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1 [Source:NCBI gene;Acc:445208])

HSP 1 Score: 682.174 bits (1759), Expect = 0.000e+0
Identity = 331/502 (65.94%), Postives = 399/502 (79.48%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++ ++  E+AAKIINTK+LS+RD QKLEREARICRLLKH NIVRLHDSI ++G HYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+PYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITAAEALKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS        S    K   G+K+   +V      TD +K  S   N       + +   +I+ +KQEIIKVTE LI +I+  +F +YTK+ D  LT F PE++GNL+EG D HRFYFEN+LSK  K  HT +LNP VHL+GE+ ACIAY+RL Q+ D +N      T Q EETR+W +R + KWQNIH HRS
Sbjct:    4 TTCTRFTDEYQLYEELGKGAFSVVRRCMKISTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHANIVRLHDSISEEGVHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITAAEALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFS--------SKNPYKKPDGVKEPQTTVIH--NPTDGNKESSESTN-------TTIEDEDIKARKQEIIKVTELLIEAINNGEFEAYTKICDPGLTSFEPEALGNLVEGTDFHRFYFENSLSKGHKPIHTILLNPHVHLIGEDAACIAYIRLTQYMDVNNMPR---TMQSEETRVWHRR-DGKWQNIHFHRS 483
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Match: camk2d2 (calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2 [Source:NCBI gene;Acc:436815])

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 342/545 (62.75%), Postives = 407/545 (74.68%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCS----NRDGSLISKKSNGGI-------------------------KDSTDSVAPAIEDTDDSK------------TPSRVMNCNSTVLKSDVSSSEI-----ETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +F+D Y++ EELG+GAFS+V+RCV+ +S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESV++CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTT+L TRNFS   S      DG  ++ K+N                            K+ST+S    IED D                PS     NS   ++  SS +      + +KQEIIKVTEQLI SI+  DF +Y K+ D  LT F PE++GNL+EG D HRFYFENALSK  K  HT +LNP VHL+GE+ ACIAY+RL Q+ D   G     T Q EETR+W +R + KW NIH HRS
Sbjct:    7 TRFTDEYQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTLLVTRNFSAAKSLLNKKPDGVKVNNKTNLASSPKDTGPAPALEPQTTVIHNPVDRNKESTESANTTIEDEDLKARRFGNLSINSIWQPSVGRPQNSEPKQAPNSSVQTCQVINKARKQEIIKVTEQLIESINNGDFEAYAKICDPGLTSFEPEALGNLVEGHDFHRFYFENALSKGNKPVHTILLNPHVHLIGEDAACIAYIRLTQYMD---GSGMPRTMQSEETRVWHRR-DGKWLNIHFHRS 546
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Match: atp6v1d (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D [Source:Xenbase;Acc:XB-GENE-973447])

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 346/506 (68.38%), Postives = 411/506 (81.23%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKS----DVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITAAEAL+HPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D   T       + T L        SSS ++++KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+GE+ ACIAY+RL Q+ D S G  K  T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTCTRFTDEYQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITAAEALRHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA------KSLLKKPD--GVKESTESSNTTIEDEDVKATKCTENTYSKTHLHESEPSRNSSSSVQSRKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHRFYFENALSKSNKPVHTIILNPHVHLIGEDAACIAYIRLTQYLD-STGMPK--TMQSEETRVWHRR-DGKWQNVHFHRS 496
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Match: atp6v1d (ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D [Source:Xenbase;Acc:XB-GENE-973447])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 340/502 (67.73%), Postives = 403/502 (80.28%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITAAEAL+HPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+GE+ ACIAY+RL Q+ D S G  K  T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTCTRFTDEYQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITAAEALRHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA------KSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHRFYFENALSKSNKPVHTIILNPHVHLIGEDAACIAYIRLTQYLD-STGMPK--TMQSEETRVWHRR-DGKWQNVHFHRS 468
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Match: camk2a (calcium/calmodulin dependent protein kinase (CaM kinase) II alpha [Source:NCBI gene;Acc:100101771])

HSP 1 Score: 686.797 bits (1771), Expect = 0.000e+0
Identity = 337/511 (65.95%), Postives = 404/511 (79.06%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTV-LKSDVSSSEIE--TKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLP 1597
             +FS+ Y++ EELG+GAFSIV+RCV+  S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++G HYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK K A VKLADFGLA+E+ E E+ +W GFAGTPGYLSPEVLRKDPYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI  R  +AS +HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS       G   S K N G+K+S++S    IED D         N N T  L++ ++  +     +KQEIIKVTEQLI +IS  DF  YTK+ D  +T F PE++GNL+EG+D HRFYFEN  S++ K  HT+ILNP +HL+G+E+ACIAY+R+ Q+ D S       T Q EET IW +R + KWQN+H HRS     S+LP
Sbjct:    7 TRFSEEYQLFEELGKGAFSIVRRCVKVLSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------GGKSGSNKKNDGVKESSESTNTTIEDEDTKDFSLAAQNENITPGLENPIAPKKPSQTVRKQEIIKVTEQLIEAISNGDFECYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRSNKPLHTTILNPHIHLMGDESACIAYIRITQYLDTSGVPR---TAQSEETCIWHRR-DGKWQNVHFHRS--GAPSVLP 504
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Match: eg435916.1 (eg435916, gene 1 [Source:Xenbase;Acc:XB-GENE-920022])

HSP 1 Score: 683.715 bits (1763), Expect = 0.000e+0
Identity = 328/524 (62.60%), Postives = 406/524 (77.48%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNR--DGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSR------VMNCNSTVLKSDVS-----SSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESL 1591
            M     +F+D Y++ EE+G+GAFS+V+RCV+  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYL+FDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA EALKHPW+ QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS  CS+R       S K++ G+      + PA   +D   +  R           + V +  +S     S   + +KQEIIK+TEQLI +++  DF +Y K+ D  LT F PE++GNL+EG+D HRFYFEN LSKN K  HT+ILNP VH++GE+ ACIAY+RL Q+ D + G  +  T Q EETR+W +R + KWQN+H H S   +  L
Sbjct:    1 MAVTCTRFTDEYQLYEEIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSGKCSSRLLQPQTNSTKNSAGVTSPKGPIPPAALFSDILSSVRRGSGALEAEGPQAAVAQQPLSPSFPHSPLAQPRKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTTFEPEALGNLVEGIDFHRFYFENLLSKNNKPIHTTILNPHVHVVGEDAACIAYIRLTQYID-TQGRPR--TSQSEETRVWHRR-DGKWQNVHFHCSGAPVAPL 519
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Match: camk2a (calcium/calmodulin dependent protein kinase (CaM kinase) II alpha [Source:NCBI gene;Acc:100101771])

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 336/516 (65.12%), Postives = 407/516 (78.88%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS--KFCSNRDGSLISKK---SNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTV-LKSDVSSSEIE--TKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLP 1597
             +FS+ Y++ EELG+GAFSIV+RCV+  S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++G HYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK K A VKLADFGLA+E+ E E+ +W GFAGTPGYLSPEVLRKDPYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI  R  +AS +HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS  K  SN+    + K+   S+  + +S++S    IED D         N N T  L++ ++  +     +KQEIIKVTEQLI +IS  DF  YTK+ D  +T F PE++GNL+EG+D HRFYFEN  S++ K  HT+ILNP +HL+G+E+ACIAY+R+ Q+ D S       T Q EET IW +R + KWQN+H HRS     S+LP
Sbjct:    7 TRFSEEYQLFEELGKGAFSIVRRCVKVLSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGHHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEV-EGEQQAWFGFAGTPGYLSPEVLRKDPYGKAVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSGGKSGSNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKDFSLAAQNENITPGLENPIAPKKPSQTVRKQEIIKVTEQLIEAISNGDFECYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRSNKPLHTTILNPHIHLMGDESACIAYIRITQYLDTSGVPR---TAQSEETCIWHRR-DGKWQNVHFHRS--GAPSVLP 515
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Match: Camk2d (calcium/calmodulin-dependent protein kinase II, delta [Source:MGI Symbol;Acc:MGI:1341265])

HSP 1 Score: 702.205 bits (1811), Expect = 0.000e+0
Identity = 340/513 (66.28%), Postives = 409/513 (79.73%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS---KFCSNRDGSLISKKSNGGIKDSTDSVAPAIE-------DTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS         DG  I+ K+N       +   PA+E       + D +K  +   + N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTE--SSNTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 504
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Match: Camk2d (calcium/calmodulin-dependent protein kinase II, delta [Source:MGI Symbol;Acc:MGI:1341265])

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 338/503 (67.20%), Postives = 404/503 (80.32%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS          + KK +G  K  + S    +E T+ S         N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFS-------AKSLLKKPDGVKKRKSSSSVQMMESTESS---------NTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 480
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Match: Camk2d (calcium/calmodulin-dependent protein kinase II, delta [Source:MGI Symbol;Acc:MGI:1341265])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 340/513 (66.28%), Postives = 409/513 (79.73%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS---KFCSNRDGSLISKKSNGGIKDSTDSVAPAIE-------DTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS         DG  I+ K+N       +   PA+E       + D +K  +   + N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTE--SSNTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 504
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Match: Camk2d (calcium/calmodulin-dependent protein kinase II, delta [Source:MGI Symbol;Acc:MGI:1341265])

HSP 1 Score: 701.049 bits (1808), Expect = 0.000e+0
Identity = 338/502 (67.33%), Postives = 402/502 (80.08%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    5 TTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Match: Camk2d (calcium/calmodulin-dependent protein kinase II, delta [Source:MGI Symbol;Acc:MGI:1341265])

HSP 1 Score: 699.893 bits (1805), Expect = 0.000e+0
Identity = 338/503 (67.20%), Postives = 402/503 (79.92%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Match: sp|Q00168|KCC2A_DROME (Calcium/calmodulin-dependent protein kinase type II alpha chain OS=Drosophila melanogaster OX=7227 GN=CaMKII PE=1 SV=1)

HSP 1 Score: 726.087 bits (1873), Expect = 0.000e+0
Identity = 350/517 (67.70%), Postives = 420/517 (81.24%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGG-IKDSTDSVAPAIEDTD---------------DSKTPSRV-MNCNSTVLKSDVSSSEIET-KKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +FSD Y++KEELG+GAFSIVKRCVQK++  EFAAKIINTK+L++RD QKLEREARICR L HPNIVRLHDSIQ++ +HYLVFDLVTGGELFEDIVAREFYSEADAS+C+QQILESVN+CHQN ++HRDLKPENLLL+SK+K A VKLADFGLA+E++ + +A W GFAGTPGYLSPEVL+K+PYGK VD+WACGVILYILLVGYPPFWDEDQ+RLY+QIK+G +DYPSPEWDTVT EAKNLINQMLTVNP KRITAAEALKHPWI QRE +AS+VHRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        S+I+KK  G  +K+STDS +  +ED D                SK P  + + C +   + ++ +S+  + ++QEIIK+TEQLI +I++ DF+ YTK+ D +LT F PE++GNL+EG+D H+FYFEN L KN K  +T+ILNP VHLLGEE ACIAYVRL Q+ D+        T Q EETR+W KR +NKWQN+H HRS
Sbjct:    8 TRFSDNYDIKEELGKGAFSIVKRCVQKSTGFEFAAKIINTKKLTARDFQKLEREARICRKLHHPNIVRLHDSIQEENYHYLVFDLVTGGELFEDIVAREFYSEADASHCIQQILESVNHCHQNGVVHRDLKPENLLLASKAKGAAVKLADFGLAIEVQGDHQA-WFGFAGTPGYLSPEVLKKEPYGKSVDIWACGVILYILLVGYPPFWDEDQHRLYSQIKAGAYDYPSPEWDTVTPEAKNLINQMLTVNPNKRITAAEALKHPWICQRERVASVVHRQETVDCLKKFNARRKLKGAILTTMLATRNFS------SRSMITKKGEGSQVKESTDSSSTTLEDDDIKEDKKGTVDRSTTVVSKEPEDIRILCPAKTYQQNIGNSQCSSARRQEIIKITEQLIEAINSGDFDGYTKICDPHLTAFEPEALGNLVEGIDFHKFYFENVLGKNCKAINTTILNPHVHLLGEEAACIAYVRLTQYIDKQGHAH---THQSEETRVWHKR-DNKWQNVHFHRS 513
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Match: sp|O77708|KCC2D_RABIT (Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Oryctolagus cuniculus OX=9986 GN=CAMK2D PE=2 SV=2)

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 340/513 (66.28%), Postives = 408/513 (79.53%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS---KFCSNRDGSLISKKSNGGIKDSTDSVAPAIE-------DTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI  R  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS         DG  I+ K+N       +   PA+E       + D +K  +   + N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+GE+ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWISHRATVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTE--SSNTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGEDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 504
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Match: sp|Q2HJF7|KCC2D_BOVIN (Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Bos taurus OX=9913 GN=CAMK2D PE=2 SV=1)

HSP 1 Score: 701.819 bits (1810), Expect = 0.000e+0
Identity = 338/503 (67.20%), Postives = 404/503 (80.32%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS          + KK +G  K  + S    +E T+ S         N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFS-------AKSLLKKPDGVKKRKSSSSVQMMESTESS---------NTTIEDEDVKA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 480
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Match: sp|Q95266|KCC2D_PIG (Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Sus scrofa OX=9823 GN=CAMK2D PE=2 SV=1)

HSP 1 Score: 700.664 bits (1807), Expect = 0.000e+0
Identity = 340/513 (66.28%), Postives = 405/513 (78.95%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPS 1600
             T   +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS      + PS
Sbjct:    4 TTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GSGMPKTMQSEETRVWHRR-DGKWQNVHFHRSGSPTVPIKPS 480
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Match: sp|Q5ZKI0|KCC2D_CHICK (Calcium/calmodulin-dependent protein kinase type II delta chain OS=Gallus gallus OX=9031 GN=CAMK2D PE=2 SV=1)

HSP 1 Score: 700.279 bits (1806), Expect = 0.000e+0
Identity = 337/499 (67.54%), Postives = 400/499 (80.16%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             +F+D Y++ EELG+GAFS+V+RC++  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESVN+CH N I+HRDLKPENLLL+SKSK A VKLADFGLA+E+ + E+ +W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KRITA+EALKHPWI QR  +ASM+HRQ+TVDCLKKFNARRKLKGAILTTMLATRNFS        SL+ K    G+K+ST+S    IED D                        ++ +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG+D HRFYFENALSK+ K  HT ILNP VHL+G++ ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQN+H HRS
Sbjct:    8 TRFTDEYQLFEELGKGAFSVVRRCMKITTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEV-QGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSA-----AKSLLKKPD--GVKESTESSNTTIEDED------------------------VKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMD---GTGMPKTMQSEETRVWHRR-DGKWQNVHFHRS 470
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Match: A0A267F019 (Protein kinase domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000566g3 PE=4 SV=1)

HSP 1 Score: 757.673 bits (1955), Expect = 0.000e+0
Identity = 362/514 (70.43%), Postives = 429/514 (83.46%), Query Frame = 2 
Query:   56 KMVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTP---SRVMNCNSTVLKSDVSSSEI-----ETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSH 1573
            +M T   KF DLY++KEE+GRGAFSIV+RCVQK + LEFAAKIINT+RLS+RDMQKLEREARICRLLKHPNIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQ++I+HRDLKPENLLL+SK+K A VKLADFGLA+E++ ++ ++W GFAGTPGYLSPEVLRKD YGKPVDVWACGVILYILLVGYPPFWDEDQ+RLYAQIK+G FDYPSPEWDTVTAEAKNLINQML  NP KRITAAEALKHPWI QRE IAS+VHRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS   +++  +   K S  GI++S DS A  IE+ +++K     +  +  + TV+KSDV +        ET+KQEIIKVTEQL+ +I++ DF++Y+KL D  +T F PE+ GNLIEG+D H+FYF++    ++K  HTSILNPTVHLL E++ACIAY+RL QF D+SN      + Q EETR+W +R ++KW N+H HRS 
Sbjct:   24 RMTT--AKFGDLYDLKEEIGRGAFSIVRRCVQKTTGLEFAAKIINTRRLSTRDMQKLEREARICRLLKHPNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQHSIVHRDLKPENLLLASKTKGAVVKLADFGLAIELQPDQSSAWFGFAGTPGYLSPEVLRKDAYGKPVDVWACGVILYILLVGYPPFWDEDQSRLYAQIKAGAFDYPSPEWDTVTAEAKNLINQMLNTNPAKRITAAEALKHPWICQRERIASVVHRQETVECLKKFNARRKLKGAILTTMLATRNFSTSSASKVVTAAKKASGNGIRESADSGATTIEEAEEAKAVNCFNATLTSSGTVVKSDVCAGGGGGGGNETRKQEIIKVTEQLLQAIASSDFDTYSKLSDPQITAFEPEAFGNLIEGLDFHKFYFDHG-KNSSKAVHTSILNPTVHLLSEDSACIAYIRLTQFLDKSNNPR---SRQSEETRVWCRR-DSKWINVHFHRSQ 530
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Match: A0A3Q0KCB8 (Protein kinase OS=Schistosoma mansoni OX=6183 PE=4 SV=1)

HSP 1 Score: 750.355 bits (1936), Expect = 0.000e+0
Identity = 361/510 (70.78%), Postives = 425/510 (83.33%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGS--LISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKN-TKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLA 1579
            M T   KFSDLY +KEE+GRGAFSIV++C+Q ++ LEFAAKIINTKRLS+RDMQKLEREARICRLLKHPNIVRL+D IQD+GFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQI+ESVNYCHQNNI+HRDLKPENLLL+SKSK A VKLADFGLA+E++ ++ A W GFAGTPGYLSPEVLRK+PYGK VDVWACGVILYILLVGYPPFWDEDQNRLY+QIKSG +DYPSPEWDTVT EAKNLIN MLTV+P +RITAAEALKHPWI QRE +AS+VHRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS       GS   ++KKSN GIK+S+DS    +ED+ D K   +++ C ST++K++   S +E+KKQ+II+ TEQL+++ +A DF  Y K +DS  T FGPE+ GNL+EG D H+FYFE  + K+  +  HTSILNPTVHL+GE+ ACIAY RL QF D+        T+Q EETR+W +R +  WQN+HVHRS L+
Sbjct:    1 MATVLPKFSDLYSLKEEVGRGAFSIVRKCIQLSTGLEFAAKIINTKRLSTRDMQKLEREARICRLLKHPNIVRLYDDIQDEGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQIIESVNYCHQNNIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQPA-WFGFAGTPGYLSPEVLRKEPYGKAVDVWACGVILYILLVGYPPFWDEDQNRLYSQIKSGAYDYPSPEWDTVTPEAKNLINLMLTVSPARRITAAEALKHPWICQRERVASLVHRQETVECLKKFNARRKLKGAILTTMLATRNFSTGRGTVPGSHTSVTKKSNDGIKESSDSSTAVMEDSADIK---KLLAC-STIVKAE---SSVESKKQDIIRATEQLLAAAAAGDFELYLKFLDSQFTYFGPEACGNLLEGADFHKFYFEQIIPKSVVRAIHTSILNPTVHLMGEDAACIAYTRLTQFLDKCGMPH---TQQTEETRVWVRRNDRGWQNVHVHRSCLS 499
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Match: A0A504Z1R5 (Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Fasciola gigantica OX=46835 GN=FGIG_04063 PE=4 SV=1)

HSP 1 Score: 748.043 bits (1930), Expect = 0.000e+0
Identity = 362/512 (70.70%), Postives = 421/512 (82.23%), Query Frame = 2 
Query:   59 MVTNNV-KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFS---KFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMS-HTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLA 1579
            M T+ + KFSDLYE+KEELGRGAFSIV+RC+Q ++ LEFA+KIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQI+ESVNYCHQNNI+HRDLKPENLLL+SKSK A VKLADFGLA+E+ +NE+ +W GFAGTPGYLSPEVLRK+PYGK VD+WACGVILYILLVGYPPFWDEDQNRLY+QIK+G +DYPSPEWDTVT EAK+LIN MLTV+PT+RITAAEALKHPWI QRE +AS++HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS      S   GS ++KK+NG IKD+TD      ED  D K    V+      L  D       +KKQ+II+ TEQL+++ +A DF++Y K +D   T FGPES GNL+EG D H+FYFE  + K+   S HTSILNPTVHL+GE++ACIAY RL QF D++N      T+Q EETR+W +R    WQN+H HRS +A
Sbjct:    1 MATSGLPKFSDLYELKEELGRGAFSIVRRCIQLSTGLEFASKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQIIESVNYCHQNNIVHRDLKPENLLLASKSKGAAVKLADFGLAIEV-QNEQPAWFGFAGTPGYLSPEVLRKEPYGKAVDIWACGVILYILLVGYPPFWDEDQNRLYSQIKTGAYDYPSPEWDTVTPEAKSLINSMLTVDPTRRITAAEALKHPWICQRERVASIMHRQETVECLKKFNARRKLKGAILTTMLATRNFSTGRTVLSGTSGS-VAKKTNGAIKDATDIPRILNEDGTDGKVEVLVLTDPKCQLGGD-------SKKQDIIRATEQLLAAAAAGDFDTYLKYLDPQFTYFGPESCGNLLEGADFHKFYFEQIIPKSVVRSIHTSILNPTVHLMGEDSACIAYTRLTQFLDKTNMPH---TQQTEETRLWVRRDGRNWQNVHAHRSAMA 500
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Match: A0A4S2LHM9 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_007200 PE=4 SV=1)

HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0
Identity = 369/524 (70.42%), Postives = 421/524 (80.34%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMS-HTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW 1645
            KFSDLYE+KEELGRGAFSIV+RC+Q ++ LEFA+KIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQI+ESVNYCHQNNI+HRDLKPENLLL+SKSK A VKLADFGLA+E+ +N++  W GFAGTPGYLSPEVLRK+PYGK VD+WACGVILYILLVGYPPFWDEDQNRLY+QIKSG FDYPSPEWDTVT EAKNLIN MLTV P++RITAAEALKHPWI QRE +ASMVHRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS   +    S   KK NGG K+++DS A A ED  D+K                       +KKQ+II+VTEQL+++ +A DF  Y K +D   T FGPE+ GNL+EGVD H+FYFE  + K+   S HT+ILNPTVHLLGE+ ACIAYVRL QF D+        T+Q EETRIW +R    WQN+HVHRS + L S   S+AT   GN   ++S+
Sbjct:    8 KFSDLYELKEELGRGAFSIVRRCIQLSTGLEFASKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQIIESVNYCHQNNIVHRDLKPENLLLASKSKGAAVKLADFGLAIEV-QNDQPQWFGFAGTPGYLSPEVLRKEPYGKAVDIWACGVILYILLVGYPPFWDEDQNRLYSQIKSGAFDYPSPEWDTVTPEAKNLINAMLTVCPSRRITAAEALKHPWICQRERVASMVHRQETVECLKKFNARRKLKGAILTTMLATRNFSTGRTVIGSS--QKKPNGGTKEASDSTAIA-EDPLDAK-----------------------SKKQDIIRVTEQLLAAAAAGDFECYAKYLDPQFTYFGPEARGNLLEGVDFHKFYFEQIIPKSVVRSIHTTILNPTVHLLGEDAACIAYVRLTQFLDKCGIPH---TQQTEETRIWTRRDGRSWQNVHVHRSCMPLSSGPASLAT---GNPNVSTSF 498
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Match: A0A267F963 (Protein kinase domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005291g1 PE=3 SV=1)

HSP 1 Score: 740.339 bits (1910), Expect = 0.000e+0
Identity = 353/505 (69.90%), Postives = 414/505 (81.98%), Query Frame = 2 
Query:   68 NNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLIS---KKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSH 1573
               KF DLY++KEE+GRGAFSIV+RCVQK + LEFAAKIINT+RLS+RDMQKLEREARICRLLKHPNIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQ++I+HRDLKPENLLL+SK+K A VKLADFGLA+E++ ++ ++W GFAGTPGYLSPEVLRKD YGKPVDVWACGVILYILLVGYPPFWDEDQ+RLYAQIK+G FDYPSPEWDTVTAEAKNLINQML  NP KRITAAEALKHPWI QRE IAS+VHRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS   S+    +++   K S  GI++S DS A  IE+ +++K                        +KQEIIKVTEQL+ +I++ DF++Y+KL D  +T F PE+ GNLIEG+D H+FYF++    ++K  HTSILNPTVHLL E++ACIAY+RL QF D+SN      + Q EETR+W +R ++KW N+H HRS 
Sbjct:    2 TTAKFGDLYDLKEEIGRGAFSIVRRCVQKTTGLEFAAKIINTRRLSTRDMQKLEREARICRLLKHPNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQHSIVHRDLKPENLLLASKTKGAVVKLADFGLAIELQPDQSSAWFGFAGTPGYLSPEVLRKDAYGKPVDVWACGVILYILLVGYPPFWDEDQSRLYAQIKAGAFDYPSPEWDTVTAEAKNLINQMLNTNPAKRITAAEALKHPWICQRERIASVVHRQETVECLKKFNARRKLKGAILTTMLATRNFSMNKSSSASKVVTAAKKASGNGIRESADSGATTIEEAEEAK-----------------------ARKQEIIKVTEQLLQAIASSDFDTYSKLSDPQITAFEPEAFGNLIEGLDFHKFYFDHG-KNSSKAVHTSILNPTVHLLSEDSACIAYIRLTQFLDKSNNPR---SRQSEETRVWCRR-DSKWINVHFHRSQ 478
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Match: camk2b1 (calcium/calmodulin-dependent protein kinase type II subunit beta [Source:NCBI gene;Acc:103043420])

HSP 1 Score: 689.108 bits (1777), Expect = 0.000e+0
Identity = 333/528 (63.07%), Postives = 413/528 (78.22%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSN-------------GGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSS------------SEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RCV+  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYL+FDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK KNA VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA EALKHPW+ QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTML +RNFS        SL++KK++              GIK+S+DS    +ED D      + ++ +S +  S+ SS              + T+KQEIIK+TEQLI +I+  DF +Y K+ D  LT F PE++GNL+EG+D HRFYFEN LSKN+K  HT+ILNP VHL+GE+ ACIAY+RL Q+ D   G  +  + Q EETR+W +R ++KWQN+H H S
Sbjct:    3 TTTCTRFTDEYQLYEELGKGAFSVVRRCVKLCTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSA-----AKSLLNKKADVKEAQSTVIHNPLDGIKESSDSSNATVEDED---MKGKSVDHSSGLAHSNPSSHPDHAHAAQSPAPAVFTRKQEIIKITEQLIEAINNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEDAACIAYIRLTQYVD---GQGRPRSSQSEETRVWHRR-DSKWQNVHFHCS 517
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Match: camk2b1 (calcium/calmodulin-dependent protein kinase type II subunit beta [Source:NCBI gene;Acc:103043420])

HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0
Identity = 330/512 (64.45%), Postives = 412/512 (80.47%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSK---TPSRVMNCNSTVLKSDVSSS------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
             T   +F+D Y++ EELG+GAFS+V+RCV+  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYL+FDLVTGGELFEDIVARE+YSEADAS+C+ QIL+SVN+ HQ++I+HRDLKPENLLL+SK KNA VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA EALKHPW+ QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTML +RNFS        SL++KK++   + S+ +V    + T+ +K     S   N  S  L+S  SS+      +++ +KQEIIK+TEQLI +I+  DF +Y K+ D  LT F PE++GNL+EG+D HRFYFEN LSKN+K  HT+ILNP VHL+GE+ ACIAY+RL Q+ D   G  +  + Q EETR+W +R ++KWQN+H H S
Sbjct:    3 TTTCTRFTDEYQLYEELGKGAFSVVRRCVKLCTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIHQILDSVNHIHQHDIVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSA-----AKSLLNKKADVKKRKSSSTVQYMPQQTNSTKNSIVTSPKGNLPSPALESSDSSNATVEDEDMKARKQEIIKITEQLIEAINNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEDAACIAYIRLTQYVD---GQGRPRSSQSEETRVWHRR-DSKWQNVHFHCS 504
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Match: camk2b2 (calcium/calmodulin-dependent protein kinase type II subunit beta [Source:NCBI gene;Acc:103033831])

HSP 1 Score: 686.026 bits (1769), Expect = 0.000e+0
Identity = 329/502 (65.54%), Postives = 407/502 (81.08%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RCV+  +  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYL+FDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK KNA VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRK+ YGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA EALKHPW+ QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTML +RNFS        SL++KK++   + S+ +V   +E +D S         N+T+   DV +     +KQEIIK+TEQLI +++  DF +Y K+ D  LT F PE++GNL+EG+D HRFYFEN LSKN+K  HT+ILNP VHL+GE+ ACIAY+RL QF D S G  +  + Q EETR+W +R ++KWQN+H H S
Sbjct:    4 TTCTRFTDEYQLYEELGKGAFSVVRRCVKLCTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLLFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKCKNAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAQEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLVSRNFSA-----AKSLLNKKADVKKRKSSSTVQ-YMESSDSS---------NTTIEDEDVKA-----RKQEIIKITEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLSKNSKPIHTTILNPHVHLIGEDAACIAYIRLTQFVD-SQGRPR--SSQSEETRVWHRR-DSKWQNVHFHCS 480
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Match: camk2g1 (calcium/calmodulin-dependent protein kinase type II subunit gamma-like [Source:NCBI gene;Acc:103032713])

HSP 1 Score: 685.641 bits (1768), Expect = 0.000e+0
Identity = 329/524 (62.79%), Postives = 412/524 (78.63%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNG---GIKDSTDSVAPAI-----EDTDDSKTPSRVMNCNSTVLKSDVSSS-------------EIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            +  + +F+D Y++ EELG+GAFS+V+RCV+K++  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS C+ QILESVN+ HQ++I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA +ALKHPW+ QR  +ASM+HRQ+TV+CL+KFNARRKLKGAILTTML +RNFS  C     SL++KK++G      ++ +SV  A+     E    S TP   M   +TV+ +    +             +++ +KQEIIK+TEQLI +++  DF +YT++ D  LT F PE++GNL+EG+D H+FYFEN LSKN K  HT+ILNP VHL+GE+ ACIAY+RL Q+ D       C   Q EETR+W +R ++KW N+H H S
Sbjct:    4 IVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASQCINQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAEQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSA-CK----SLLNKKADGVKPQTNNTKNSVVSAVVSALKESNSASSTP---MEPQTTVVHNPADGTKGSTESCNTNEEEDMKVRKQEIIKITEQLIEAVNNGDFEAYTRICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNNKPVHTTILNPHVHLIGEDAACIAYIRLTQYIDSQGRPRSC---QSEETRVWHRR-DSKWLNVHFHCS 514
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Match: camk2g2 (calcium/calmodulin dependent protein kinase II gamma [Source:NCBI gene;Acc:103044561])

HSP 1 Score: 684.871 bits (1766), Expect = 0.000e+0
Identity = 327/503 (65.01%), Postives = 407/503 (80.91%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            +  + +F+D Y++ EELG+GAFS+V+RCV+K++  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+ QILESV++ HQ++I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA +ALKHPW+ QR  +ASM+HRQ+TV+CL+KFNARRKLKGAILTTML +RNFS  C     SL++KKS+G  K  + S    +  T+         +CN+T  + D+     + +KQEIIK+TEQLI +I+  DF +YT++ D  LT F PE++GNL+EG+D H+FYFEN LSKN+K  HT+ILNP VHL+GE+ ACIAY+RL Q+ D       C   Q EETR+W +R + KW N+H H S
Sbjct:    4 IATSTRFTDEYQLYEELGKGAFSVVRRCVKKSTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCINQILESVSHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSA-CK----SLLNKKSDGVKKRKSSSSVYLMGSTE---------SCNTTE-EEDMKGR--KARKQEIIKITEQLIEAINNGDFEAYTRICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPVHTTILNPHVHLIGEDAACIAYIRLTQYIDSQGRPRSC---QSEETRVWHRR-DAKWLNVHFHCS 484
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008748.1 (pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 gene:ENSPMAG00000007907.1 transcript:ENSPMAT00000008748.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 548.51 bits (1412), Expect = 0.000e+0
Identity = 257/362 (70.99%), Postives = 309/362 (85.36%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDV 1162
            +F+D Y++ EELG+GAFS+V+RCV+ ++  EFAAKIINTK+LS+RD QKLEREARICRLLKH NIVRLH+SI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESV++CHQ+ I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVTAEAKNLINQMLT+NP KRITAAEALKHPWI QR  +AS +HRQ+TV+CL+KFNARRKLKGAILTTMLATRNFS        SL++KK+  G+K    S +  + ++ +S         N+T+   DV
Sbjct:    9 RFTDEYQLYEELGKGAFSVVRRCVKVSTGQEFAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHESIAEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHQHGIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTAEAKNLINQMLTINPAKRITAAEALKHPWICQRSTVASCMHRQETVECLRKFNARRKLKGAILTTMLATRNFSA-----AKSLLNKKTQDGVKKRKSSASVQVLESSESS--------NTTIEDEDV 356
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Match: camk2a (calcium/calmodulin-dependent protein kinase II alpha [Source:ZFIN;Acc:ZDB-GENE-051113-72])

HSP 1 Score: 476.478 bits (1225), Expect = 2.263e-165
Identity = 228/341 (66.86%), Postives = 275/341 (80.65%), Query Frame = 2 
Query:  329 VTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFEN 1351
            VTGGELFEDIVARE+YSEADAS  +QQILE+V +CHQ  I+HRDLKPENLLL+SK+K A VKLADFGLA+E+ + E+ +W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LINQMLT+NP KRITA+EAL HPWI+QR  +AS +HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS        SL++KK++ G+K+STDS    +ED D               LK   +   ++ +KQEIIKVTEQLI +++  DF +YTKL D  +T F PE++GNL+ G++ H+FYFEN
Sbjct:    1 VTGGELFEDIVAREYYSEADASTGIQQILEAVLHCHQLGIVHRDLKPENLLLASKTKGAAVKLADFGLAIEV-QGEQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKSLINQMLTINPAKRITASEALTHPWIFQRSTVASCMHRQETVECLKKFNARRKLKGAILTTMLATRNFSA-----AKSLMNKKTD-GVKESTDSSNTTLEDED---------------LKLKKTKCSLKMRKQEIIKVTEQLIEAVNHGDFEAYTKLCDPGMTSFEPEALGNLVGGMEFHKFYFEN 319
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Match: phkg1b (phosphorylase kinase, gamma 1b (muscle) [Source:ZFIN;Acc:ZDB-GENE-050522-52])

HSP 1 Score: 234.958 bits (598), Expect = 7.278e-71
Identity = 126/322 (39.13%), Postives = 188/322 (58.39%), Query Frame = 2 
Query:   80 FSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTK--RLSSRDMQKLE----REARICRLLK-HPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLR------KDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKF 1006
            F+D YE KE LG G  S+V+RCV K +  +FA KII+    RLS  +++ +     +E  I + +  HP+I+ L D+ +   F +LVFDL+  GELF+ +  +   SE D  + M+ I E V++ H  NI+HRDLKPEN+LL     N  ++L+DFG +++++  E    L   GTPGYLSPE+L+         YGK VD+WACGVI+Y LL G PPFW   Q  +   I  G +D+ +PEW+  +   K+LI+++L V P KR TA +AL HP+            +Q  V+ ++ F+  RK K  +LT + + R +  +
Sbjct:   21 FNDKYEPKEVLGSGVSSVVRRCVHKRTGQDFAVKIIDITPDRLSEEELEDIYSSTVKEVDILKAVSGHPHIITLIDAYESSTFFFLVFDLMKRGELFDYLTEKVALSEKDTRSIMRSIFEVVHFLHAKNIVHRDLKPENILLDD---NMNIRLSDFGFSMQLRPGERLREL--CGTPGYLSPELLKCSMDESHPGYGKEVDLWACGVIMYTLLAGSPPFWHRKQMTMLRLIMDGKYDFSTPEWEDRSDTVKDLISRLLVVEPEKRFTAEQALAHPFF-----------QQYDVEEVRHFSPYRKFKTIMLTVLASVRMYYHY 326
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Match: RPS6KA3 (ribosomal protein S6 kinase A3 [Source:HGNC Symbol;Acc:HGNC:10432])

HSP 1 Score: 212.231 bits (539), Expect = 5.263e-64
Identity = 106/274 (38.69%), Postives = 169/274 (61.68%), Query Frame = 2 
Query:   68 NNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKII--NTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNAR-VKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFW---DEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWI 871
            N+V+FSD YE++E++G G++S+ KRC+ K +N+E+A K+I   +KR  S +++ L R        +HPN++ L D   D    YLV +L+ GGEL + I+ ++F+SE +AS  +Q I  +V Y H   ++HRDLKP N+L   +S N   +++ DFG A +++  E    +    T  +++PEVL++  Y    D+W+ GV+LY +L G+ PF    D+    +  +I SG F      WDTV+  AK+L+ +ML V+P +R TAA+ L+HPWI
Sbjct:    4 NSVQFSDGYELREDIGVGSYSVCKRCIHKTTNMEYAVKVIIDKSKRDPSEEIEILLRYG------QHPNVITLKDVYDDGKSVYLVTELMKGGELLDKILRQKFFSEREASAVLQTIARTVEYLHSQGVVHRDLKPSNILYVDESGNPESLRICDFGFAKQLRA-ENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLAGHTPFANGPDDTPGVILTRIGSGRFLLSGGNWDTVSEAAKDLVKKMLHVDPHQRFTAAQVLRHPWI 270
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003135.1 (pep scaffold:Pmarinus_7.0:GL491838:799:5626:1 gene:ENSPMAG00000002863.1 transcript:ENSPMAT00000003135.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 201.445 bits (511), Expect = 3.254e-60
Identity = 106/259 (40.93%), Postives = 155/259 (59.85%), Query Frame = 2 
Query:  116 RGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVT----GGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFA-GTPGYLS---PEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPW 868
            RGAFS V    ++++    A K I    L  +D   +E E  +   +KH NI+ L D  + D   YL+  LV     GGELF+ IV R FY+E DAS  ++Q+L +V++ H   ++HRDLKPENLL  S   ++++ ++DFGL+   K     S +  A GTPGY++   PEVL + PY + VD W+ GVI YILL GYPPF+DE  +RL+ QI    +++ SP WD ++  AK+ I  ++  +  +R T  +AL+HPW
Sbjct:    1 RGAFSEVVLAEERSTGRHVAIKCIAKTALRGKD-NTVENEVCVLSRIKHENIIALEDIYETDSHLYLIMQLVLLLIRGGELFDRIVERGFYTERDASALIRQVLRAVSHLHGQGVVHRDLKPENLLYYSAEDDSKIMISDFGLS---KVEAPGSVMSTACGTPGYVACEAPEVLAQKPYTRAVDCWSIGVISYILLCGYPPFYDEVDSRLFDQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDVAERFTCEQALQHPW 255
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Match: CMK2 (Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005376])

HSP 1 Score: 206.453 bits (524), Expect = 6.128e-60
Identity = 115/304 (37.83%), Postives = 169/304 (55.59%), Query Frame = 2 
Query:   92 YEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRD--MQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLF--DYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATR 991
            Y     LG G+F +V++  + ++N + A KI+  K L   +  +Q L  E  I + L HPNIV   D  +     Y+V  L TGGELF+ I++R  ++E DA   + QIL +V Y H  N++HRDLKPEN+L   KS+N+ + +ADFG+A ++K  E+  +   AG+ GY++PEVL +D +GKP D+W+ GVI Y LL GY PF  E       +  +  +   +  P WD ++ + K  I + L +NP  R TA E L  PWI  +    S +      D  K F+ R+KL+ AI    L  R
Sbjct:   47 YIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKA-AGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNI----LPDVKKGFSLRKKLRDAIEIVKLNNR 345
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Match: CMK1 (Calmodulin-dependent protein kinase; may play a role in stress response, many Ca++/calmodulin dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to mammalian Cam Kinase II; CMK1 has a paralog, CMK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001910])

HSP 1 Score: 197.593 bits (501), Expect = 1.031e-56
Identity = 129/396 (32.58%), Postives = 204/396 (51.52%), Query Frame = 2 
Query:   92 YEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQ--KLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYP----SPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKK-FNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDST--DSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNS 1252
            Y   + LG G F +V++     +  + A KI+  K L    +Q   L  E  I + L HPNIV   D  +     Y++  L  GGELF+ I+ +  ++E DA   + +IL +V Y H  NI+HRDLKPENLL   KS  + + +ADFG+A  +K +EE  +   AG+ GY++PEVL +D +GKP D+W+ GVI Y LL GY  F  E       +  +G  +YP     P WD+V+ +AK  I + L ++P+KR TAAE L+ PWI     I + +     +  LK+  +AR+K + ++    L      K    RD  L   +S+    + +  +   P ++ TD S+   ++     + LKS+++S         ++   E+ ++    C  +S
Sbjct:   37 YVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKP-AGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTG--EYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWI-----ICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNM----KIQKLRDLYLEQTESDSDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVNTVLAEKEKFLNINRVCSSDS 420
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Match: SNF1 (AMP-activated S/T protein kinase; forms a complex with Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis; regulates nucleocytoplasmic shuttling of Hxk2p; regulates filamentous growth and acts as a non-canonical GEF, activating Arf3p during invasive growth; SUMOylation by Mms21p inhibits its function and targets Snf1p for destruction via the Slx5-Slx8 Ub ligase [Source:SGD;Acc:S000002885])

HSP 1 Score: 185.267 bits (469), Expect = 8.738e-51
Identity = 107/263 (40.68%), Postives = 156/263 (59.32%), Query Frame = 2 
Query:   92 YEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQ-KLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFA-GTPGYLSPEVLRKDPYGKP-VDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWI 871
            Y++ + LG G+F  VK      +  + A KIIN K L+  DMQ ++ERE    RLL+HP+I++L+D I+      +V +   G ELF+ IV R+  SE +A    QQI+ +V YCH++ I+HRDLKPENLLL    ++  VK+ADFGL+  M    + ++L  + G+P Y +PEV+    Y  P VDVW+CGVILY++L    PF DE    L+  I +G++  P      ++  A  LI +ML VNP  RI+  E ++  W 
Sbjct:   55 YQIVKTLGEGSFGKVKLAYHTTTGQKVALKIINKKVLAKSDMQGRIEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEYA-GNELFDYIVQRDKMSEQEARRFFQQIISAVEYCHRHKIVHRDLKPENLLL---DEHLNVKIADFGLSNIMT---DGNFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYVMLCRRLPFDDESIPVLFKNISNGVYTLPK----FLSPGAAGLIKRMLIVNPLNRISIHEIMQDDWF 306
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Match: DUN1 (Cell-cycle checkpoint S/T protein kinase; required for transient G2/M arrest after DNA damage, damage-induced transcription, and nuclear-to-cytoplasmic redistribution of Rnr2p-Rnr4p after genotoxic stress and iron deprivation; phosphorylates repair protein Rad55p, transcriptional repressor Sml1p, superoxide dismutase, and ribonucleotide reductase inhibitors Crt1p and Dif1p; functions in the Mec1p pathway to regulate dNTP pools and telomere length; postreplicative repair role [Source:SGD;Acc:S000002259])

HSP 1 Score: 181.8 bits (460), Expect = 2.022e-50
Identity = 111/312 (35.58%), Postives = 163/312 (52.24%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLERE-ARICRLLKHPNIVRLHDSI-----QDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSK----------------NARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDE-DQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPW---IYQREHIASMVHRQQTVD 922
            T  V F D Y + +ELG G +++VK    K +  + A KI + ++   +   K  RE   I   ++HPNIV L DS      +     YLV + +  GELFE IV +    + ++    +Q+L  + Y H+ NIIHRD+KPEN+LL+   +                + +VK+ADFGLA    E +  + L   GTP Y++PEVL K  Y   VD+W+ GVILY+ L G+PPF D+     L  QI    + + SP WD +     +LI+ +L +NP +R    EAL HPW   I Q+  ++  + R Q  D
Sbjct:  191 TRPVSFFDKYLLGKELGAGHYALVKEAKNKKTGQQVAVKIFHAQQNDDQKKNKQFREETNILMRVQHPNIVNLLDSFVEPISKSQIQKYLVLEKIDDGELFERIVRKTCLRQDESKALFKQLLTGLKYLHEQNIIHRDIKPENILLNITRRENPSQVQLGPWDEDEIDIQVKIADFGLAKFTGEMQFTNTL--CGTPSYVAPEVLTKKGYTSKVDLWSAGVILYVCLCGFPPFSDQLGPPSLKEQILQAKYAFYSPYWDKIDDSVLHLISNLLVLNPDERYNIDEALNHPWFNDIQQQSSVSLELQRLQITD 500
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Match: HSL1 (Nim1p-related protein kinase; septin-binding kinase that localizes to the bud neck septin ring and regulates the morphogenesis checkpoint; phosphorylates Hsl7p and cooperates with Elm1p to recruit Hsl7p to the mother-bud neck, as a prerequisite for the subsequent recruitment, phosphorylation, and degradation of Swe1p; autophosphorylation enhances interactions with Hsl7p [Source:SGD;Acc:S000001584])

HSP 1 Score: 182.57 bits (462), Expect = 1.558e-48
Identity = 94/218 (43.12%), Postives = 142/218 (65.14%), Query Frame = 2 
Query:  224 LEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFA-GTPGYLSPEVLRKDPY-GKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWI 871
            +ERE  I +L+ H N++ L +  ++    YLV + V GGELF+ +V++    E +A +  +QI+E V+YCH  NI HRDLKPENLLL    KN R+K+ADFG+A     N+    L  + G+P Y SPE++   PY G P DVW+CG++L+ LL G+ PF D++  +L  +++SG +  PS     +++EA++LI+++L ++P KRIT  E LKHP I
Sbjct:  161 IEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLD--KKNRRIKIADFGMAALELPNK---LLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDNIKKLLLKVQSGKYQMPS----NLSSEARDLISKILVIDPEKRITTQEILKHPLI 369
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Match: EDO30537 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T0H5])

HSP 1 Score: 646.351 bits (1666), Expect = 0.000e+0
Identity = 313/502 (62.35%), Postives = 394/502 (78.49%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T++  F D YE+KEELG+GAFSIV+RC+ K S +E+AAKIINT++LSSRD+QKL+REARICRLLKHPNIVRLH SI ++G+HYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQI+ESV +CH NN++HRDLKPENLLL+SK KNA VKLADFGLA+E+ E E+  W GFAGTPGYLSPEVL+K+PYGKPVD+WACGVILYILLVGYPPFWDEDQ++LYAQIK+G +DYPSPEWDTVT EAK+LIN MLTV+ +KRI A EALKHPWI  RE +AS VHRQ+T+D LKKFNARRKLKGAILTT+LAT NF+   +             G ++S + +    ED +     ++V                   ++QEII++T++LI+SI+  D+++Y+KLVD ++TCF P S GNL+EG++ H+FYF+N LSK +   +T+IL+P VH+LGE+ ACI Y+RL Q  + S+G +K L  Q EETR+WQK+  N W N+H H S
Sbjct:    4 THSRGFHDTYELKEELGKGAFSIVRRCIHKESRIEYAAKIINTRKLSSRDLQKLDREARICRLLKHPNIVRLHASIAEEGYHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQIIESVQHCHTNNVVHRDLKPENLLLASKEKNAAVKLADFGLAIEV-EIEKTGWYGFAGTPGYLSPEVLKKEPYGKPVDLWACGVILYILLVGYPPFWDEDQHKLYAQIKTGNYDYPSPEWDTVTDEAKDLINMMLTVDQSKRIGAGEALKHPWIVNRERVASKVHRQETLDGLKKFNARRKLKGAILTTILATSNFNTNIA-------------GAQNSDEELMAHSEDEEGQDVTAKV-------------------REQEIIRLTQKLITSITTGDYDTYSKLVDPHVTCFEPFSNGNLVEGLEFHKFYFDNTLSKRSVPINTTILSPHVHVLGEDAACICYMRLTQSVN-SSGEAKTL--QQEETRVWQKKGGN-WINVHFHIS 468
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Match: EDO49898 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF52])

HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0
Identity = 300/507 (59.17%), Postives = 381/507 (75.15%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAI-EDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCL--TEQFEETRIWQKRPNNKWQNIHVHRS 1570
            ++T    F++ YE+KEELG+GAFS V++C  + + +E+A KI++TK ++ RD+ K+EREARICR L+HPN+VRLH +I  DGF++LVFDLVTGGELFEDIVARE+YSEADAS+C+QQ+L SV +CH+N I+HRDLKPENLLL+S+ + A VKLADFGLA+E+ + E   W GFAGTPGYLSPEVL+KDPYGKPVD+WACGVILYILLVGYPPFWDE+Q +LY+QIK+G +DYPSPEWDTVTA+AK+LI++MLTV+  KRITAAEALKHPWI  RE IAS VHRQQT+D LK+FNARRKL+GAI  T+LAT NFS       GS   KK +       DS+A  I EDT+ +KT                       ++QEII++T+QLI+SI+A DF+SY+KLVD  +T F PE++GN +EG++ H+FYF+N  +K     +T+IL P V +LGEE ACI+YVRL Q       G   L  T Q EETR+WQK+    W N+H HRS
Sbjct:    6 IITEGGTFNEKYELKEELGKGAFSTVRKCCHRETKIEYAVKILDTKNMTQRDVHKVEREARICRHLRHPNVVRLHANIMSDGFYFLVFDLVTGGELFEDIVAREYYSEADASHCIQQVLLSVQHCHENGIVHRDLKPENLLLASRERGAMVKLADFGLAIEV-DGERLGWYGFAGTPGYLSPEVLKKDPYGKPVDLWACGVILYILLVGYPPFWDEEQQKLYSQIKAGTYDYPSPEWDTVTADAKDLIDKMLTVDAPKRITAAEALKHPWIVNRERIASKVHRQQTLDGLKRFNARRKLRGAIHATILATHNFS------SGSRHKKKGS-----DEDSIATIIEEDTESTKT----------------------QREQEIIRLTQQLITSITAKDFDSYSKLVDPKITAFEPEALGNQVEGLEFHKFYFDNLPNKRNTTVNTTILAPHVQMLGEEGACISYVRLTQ-----GIGPDGLPRTTQSEETRVWQKK-KGVWLNVHFHRS 472
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Match: EDO33022 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7STC5])

HSP 1 Score: 264.618 bits (675), Expect = 3.151e-83
Identity = 138/310 (44.52%), Postives = 193/310 (62.26%), Query Frame = 2 
Query:   74 VKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNAR---VKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASM-VHRQQTVDCLKKFNARRKLKGAILTTMLATR 991
            +KF D+YE+ + +G+GAF  V +CV   +   FA K I+    S  D +K + EA+IC LL HP+IV L D         LV + + GG+LF+ +V R  +SE DA  C++Q+L+++ Y  +  IIHRDLKPENLLLS +  + R   +KL DFG+A ++K N         G+P YL+PE + ++     VD+WACGVILY+LLVGYPPFW+E    L   I    + +PSP WDTV+  AK+LI +ML V+P  RITA EALKH W+   + I  + ++RQ T+  L  FNARRKL+G +L  +   R
Sbjct:    1 MKFEDVYEITDFIGKGAFGQVSKCVNLQTREVFAVKEIDFSG-SEEDKKKAQNEAKICGLLDHPSIVHLEDVFFTPRRMLLVLEYLPGGDLFDGVVTRTQFSEKDACACVRQVLKALRYLTRKGIIHRDLKPENLLLSERPSDHRPPIIKLTDFGIAKQLKGN---------GSPLYLAPETILEEGLTYAVDIWACGVILYLLLVGYPPFWNEQTEFLLLSILQSNYTFPSPYWDTVSEPAKDLIRKMLVVDPRDRITAVEALKHEWVSGSDDIPGLRLNRQSTLVRLTAFNARRKLRGVVLGLIARKR 300
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Match: EDO42276 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1X1])

HSP 1 Score: 258.455 bits (659), Expect = 1.429e-80
Identity = 130/318 (40.88%), Postives = 206/318 (64.78%), Query Frame = 2 
Query:   50 IFKMVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSK 1003
             F+ ++      D Y++ +ELGRGA S+VK C QK +N EFA KI+      + D + ++ E  I   + HPNI+ + +  +     ++V +LVTGGELF+ +V + +Y E DA++ ++ ILE+V + H+N+I+HRDLKPENLL +++ +++ +K+ADFGL+  + +    S +   GTPGY +PEVL+ + Y   VD+WA GVI YILL G+ PF+DE   +++ +I    +D+ SP WD V++ AK+L+ +++T +  KR+TA +AL HPW+  +   A     ++T   LK+FNA+RKLKG +L  M A  NF+K
Sbjct:    4 FFEDLSRKEPIEDFYDIGKELGRGASSVVKLCRQKGTNKEFAVKIMK----KTVDKKIIQTETGILFRINHPNIIHMKELFETHTHLFMVLELVTGGELFDRVVEKGYYCEKDAADAIKMILEAVGHLHKNDIVHRDLKPENLLYANEREDSPLKIADFGLSKILPQEVMTSTV--CGTPGYCAPEVLKGESYDTGVDMWAIGVIAYILLCGFEPFYDETDQQMFQRILKCDYDFVSPWWDDVSSGAKDLVKRLITGDKNKRLTAKQALDHPWV--KGENARREDMERTRKKLKEFNAKRKLKGGMLGVM-AAENFAK 312
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Match: EDO36253 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJ85])

HSP 1 Score: 242.662 bits (618), Expect = 9.548e-75
Identity = 123/292 (42.12%), Postives = 181/292 (61.99%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFA-GTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARR 949
            K +  Y+++E LG GAFS V    +KA+   FA K I+ K L  ++ + +E E  I + ++H NI+ L D   +    YLV DLV GGELF+ IV +  Y+E DAS  +QQILE+ +Y H   I+HRDLKPENLL  S  +++++ ++DFGL+   K   + S++  A GTPGY++PEVL++ PYGK VD W+ GVI YILL GYPPF+D+    L+AQI    +++ SP WD ++  AK+ I  ++ ++P  R T  +AL HPWI   E +   +H   +    K F  ++
Sbjct:   12 KITKKYDLREVLGTGAFSEVVLAEEKATGSLFAVKCISKKELKGKE-ESVENEIAILKKVRHKNIIGLKDIFDNKSHLYLVMDLVQGGELFDRIVEKGNYTEQDASALVQQILEAADYLHSLGIVHRDLKPENLLYYSPDEDSKIMISDFGLS---KIEAQGSFMDTACGTPGYVAPEVLKQQPYGKAVDCWSIGVITYILLCGYPPFYDDSDANLFAQIMRAEYEFDSPYWDEISESAKDFIRHLMELDPKLRYTCRQALSHPWICGGEALTRDIHASVSEQIKKNFYKQK 299
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Match: ENSORLT00000033503.1 (calcium/calmodulin-dependent protein kinase type II delta 1 chain [Source:NCBI gene;Acc:101172229])

HSP 1 Score: 687.952 bits (1774), Expect = 0.000e+0
Identity = 329/502 (65.54%), Postives = 399/502 (79.48%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++ ++  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KR+TA + LKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS        SL++KK + G+K+S++S    IED D                        +  +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG D HRFYFENA  K  +  HT +LNP VHL+G++ ACIAY+RL Q+ D   GG    T Q EETRIW +R ++KWQNIH HRS
Sbjct:    4 TTCTRFTDEYQLYEELGKGAFSVVRRCMKISTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQADQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRVTATDVLKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSA------KSLLAKKPD-GVKESSESTNTTIEDED------------------------VRARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGTDFHRFYFENAPPKGKQPIHTILLNPHVHLIGDDAACIAYIRLTQYID---GGGLPRTTQSEETRIWHRR-DSKWQNIHFHRS 469
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Match: ENSORLT00000046433.1 (calcium/calmodulin-dependent protein kinase type II delta 1 chain [Source:NCBI gene;Acc:101172229])

HSP 1 Score: 684.485 bits (1765), Expect = 0.000e+0
Identity = 329/502 (65.54%), Postives = 403/502 (80.28%), Query Frame = 2 
Query:   65 TNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            T   +F+D Y++ EELG+GAFS+V+RC++ ++  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILE+V +CHQ  ++HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP KR+TA + LKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTTMLATRNFS        SL++KK + G+K+   +V     + +   + S     N+T+   DV +     +KQEIIKVTEQLI +I+  DF +YTK+ D  LT F PE++GNL+EG D HRFYFENA  K  +  HT +LNP VHL+G++ ACIAY+RL Q+ D   GG    T Q EETRIW +R ++KWQNIH HRS
Sbjct:    4 TTCTRFTDEYQLYEELGKGAFSVVRRCMKISTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQADQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRVTATDVLKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSA------KSLLAKKPD-GVKEPQSTVIHNPPEGNKESSES----TNTTIEDEDVRA-----RKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGTDFHRFYFENAPPKGKQPIHTILLNPHVHLIGDDAACIAYIRLTQYID---GGGLPRTTQSEETRIWHRR-DSKWQNIHFHRS 484
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Match: camk2d2 (calcium/calmodulin-dependent protein kinase type II delta 2 chain [Source:NCBI gene;Acc:101168431])

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 331/503 (65.81%), Postives = 397/503 (78.93%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            +T   +F+D Y++ EELG+GAFS+V+RCV+ +S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+QQILESV++CH N I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ+RLY QIK+G +D+PSPEWDTVT EAK+LIN+MLT+NP+KRITAAEALKHPWI QR  +ASM+HRQ+TV+CLKKFNARRKLKGAILTT+L TRNFS   +     +        + +  ++V       D    P+ V     TV        +++ +KQEIIKVTEQLI SI+  DF +Y K+ D  LT F PE++GNL+EG D HRFYFENALSK  K  HT +LNP VHL+GE  ACIAY+RL Q+ D   G     T Q EETR+W +R + KWQNIH HRS
Sbjct:    3 LTICTRFTDEYQLFEELGKGAFSVVRRCVKISSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVHHCHVNGIVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPSKRITAAEALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTLLVTRNFSGMENVCMCVMCPLHCPLQVNNKANTVT---SPKDTGPAPALVYTLICTV------DEDVKARKQEIIKVTEQLIESINNGDFEAYAKICDPGLTSFEPEALGNLVEGHDFHRFYFENALSKGNKPVHTILLNPHVHLIGENAACIAYIRLTQYMD---GSGMPRTMQSEETRVWHRR-DGKWQNIHFHRS 491
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Match: camk2g2 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101159287])

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 325/503 (64.61%), Postives = 407/503 (80.91%), Query Frame = 2 
Query:   62 VTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            V  + +F+D Y++ EELG+GAFS+V+RCV+K+++ E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+ QILES+++ HQ++I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA +ALKHPW+ QR  +ASM+HRQ+TV+CL+KFNARRKLKGAILTTML +RNFS  C     +L++KKS+ G+K++  ++     D     T S    CN+     +      + +KQEIIK+TEQLI +I+  DF +YT++ D  LT F PE++GNL+EG+D H+FYF+N LSKN+K  HT+ILNP VHL+GE+ ACIAY+RL QF D       C   Q EETR+W +R + KW N+H H S
Sbjct:    4 VVTSTRFTDEYQLYEELGKGAFSVVRRCVKKSTSQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESISHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSA-CK----TLLNKKSD-GVKEAQTTIVHNPADGTKGSTES----CNNA---EEEEMKGRKARKQEIIKMTEQLIEAINNGDFEAYTRICDPGLTSFEPEALGNLVEGMDFHKFYFDNLLSKNSKPVHTTILNPHVHLIGEDAACIAYIRLTQFIDGQGRPRSC---QSEETRVWHRR-DAKWLNVHFHCS 488
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Match: ENSORLT00000013395.2 (calcium/calmodulin-dependent protein kinase type II subunit gamma [Source:NCBI gene;Acc:101170226])

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 332/531 (62.52%), Postives = 414/531 (77.97%), Query Frame = 2 
Query:   71 NVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDG----------------SLISKKSNGG---IKDSTDSVAPAIEDTDDSKTPSRV-MNCNSTVL-----------KSDVSSSEIETK--KQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVH 1564
            + +F+D Y++ EELG+GAFS+V+RCV+K+S  E+AAKIINTK+LS+RD QKLEREARICRLLKHPNIVRLHDSI ++GFHYLVFDLVTGGELFEDIVARE+YSEADAS+C+ QILESVN+ HQ++I+HRDLKPENLLL+SK K A VKLADFGLA+E++ +++A W GFAGTPGYLSPEVLRKDPYGKPVD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +D+PSPEWDTVT EAKNLINQMLT+NP KRITA +ALKHPW+  R  +ASM+HRQ+TV+CL+KFNARRKLKGAILTTML +RNFS    + +                 SL++KKS+       +S +S+  AI    D+   +   M   STV+           +S+ ++ E E K  KQEIIK+TEQLI +I+  DF +YT++ D  LT F PE++GNL+EG+D H+FYFEN LSKN+K  HT++LNP VHL+GE+ ACIAY+RL QF D S G  +  + Q EETR+W +R + KW N+H H
Sbjct:    7 STRFTDEYQLYEELGKGAFSVVRRCVKKSSGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCISQILESVNHIHQHDIVHRDLKPENLLLASKMKGAAVKLADFGLAIEVQGDQQA-WFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITAEQALKHPWVCHRSTVASMMHRQETVECLRKFNARRKLKGAILTTMLVSRNFSVGRQHTNSAAAASSTASLAQEACKSLLNKKSDSAKPSTNNSKNSIVSAINALKDTNMATNAQMESQSTVVHNPPDGVKGSTESNATNDEEEMKARKQEIIKITEQLIEAINNGDFEAYTRICDPGLTSFEPEALGNLVEGMDFHKFYFENLLSKNSKPVHTTLLNPHVHLIGEDAACIAYIRLTQFVD-SMGRPR--SSQSEETRVWHRR-DGKWLNVHFH 532
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Match: SMESG000008997.1 (SMESG000008997.1)

HSP 1 Score: 1107.43 bits (2863), Expect = 0.000e+0
Identity = 529/529 (100.00%), Postives = 529/529 (100.00%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW 1645
            MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW
Sbjct:    1 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW 529
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Match: SMESG000008997.1 (SMESG000008997.1)

HSP 1 Score: 1080.86 bits (2794), Expect = 0.000e+0
Identity = 519/529 (98.11%), Postives = 520/529 (98.30%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW 1645
            MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNF         S+ISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW
Sbjct:    1 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNF---------SMISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRSHLALESLLPSVATCFIGNQAKTSSW 520
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Match: SMESG000029689.1 (SMESG000029689.1)

HSP 1 Score: 670.618 bits (1729), Expect = 0.000e+0
Identity = 324/499 (64.93%), Postives = 397/499 (79.56%), Query Frame = 2 
Query:   77 KFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSK-NTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            K SDLY++KEELGRGAFSIV+RCVQK+++LEFAAKIINTK+L++RDMQKLEREARICRLLKHPNIVRLHD+IQD+GFHY++FDL+TGGELFEDIVAREFYSEADASNCMQQILESVNYCH +NI+HRDLKPENL+L+SK+K A VKLADFGLA+E+ + +  SW GFAGTPGYLSPEVLRKDPYGK VDVWACGVILYILLVGYPPFWDEDQ++LY+QIKSG FDYPSPEWDTVT+EAK+LIN ML +N +KRI+AA+AL+HPWI QRE +AS  HRQ+TVDCLKKFNARRKLKGAILTTM+ATRNFSK  S+R    I+  +N G K  TD+                     + V  ++  S ++  KKQE++KVTE L S I+  D+ S+ KLVD  +T F P S GNL+EG++  +F+F+ A +K + K  + +IL+P VHLL ++NA IAY+++ Q+ DR    +    +Q EETR+W K+   KW N+H H S
Sbjct:    8 KVSDLYDIKEELGRGAFSIVRRCVQKSTSLEFAAKIINTKKLNARDMQKLEREARICRLLKHPNIVRLHDNIQDEGFHYMIFDLITGGELFEDIVAREFYSEADASNCMQQILESVNYCHMHNIVHRDLKPENLILASKTKGAAVKLADFGLAIEV-QADALSWYGFAGTPGYLSPEVLRKDPYGKLVDVWACGVILYILLVGYPPFWDEDQSKLYSQIKSGAFDYPSPEWDTVTSEAKHLINSMLQINTSKRISAADALRHPWICQRERVASAFHRQETVDCLKKFNARRKLKGAILTTMIATRNFSKILSDRKNKSIT-SANSGKKTITDT---------------------TEVTSTNDESDDLRIKKQEVLKVTELLESHIATGDYASFAKLVDPQITYFEPLSKGNLMEGIEFQKFFFDTAFAKRDGKSININILSPAVHLLNDDNAFIAYIKVTQYVDRQGMPN---VKQSEETRVWCKK-EGKWMNVHWHSS 479
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Match: SMESG000062800.1 (SMESG000062800.1)

HSP 1 Score: 669.463 bits (1726), Expect = 0.000e+0
Identity = 331/512 (64.65%), Postives = 401/512 (78.32%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSD-------VSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSK-NTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M     KFSDLYE+K+ELGRGAFSIVK+CVQ ++ LEFAAKIINTKRLS+RD+QKLEREARICRLLKH NIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSE DASNCMQQILESV+YCH +NI+HRDLKPENLLL+SK+K A VKLADFGLA+E+ + +  +W GFAGTPGYLSPEVLRK+PYGK VD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +DYPSPEWDTVT EAK LIN ML VN +KRI+AAEALK+PWI QR+ +ASM HRQQTVDCL+KFNARRKLKGAILTTMLAT+NF                         S+A +I ++  ++  ++    N+ V KSD        ++++ + KKQEI+K+TE L+SSI+  +++S+ KLVD  +T F P++ GNLIEG+D ++F F N  SK + K  + SILNPT+H+LGE+ A IA+V++VQ  D+ NG       + EETRIWQ R   KWQNIHVH+S
Sbjct:    1 MAVTVAKFSDLYELKDELGRGAFSIVKKCVQLSTGLEFAAKIINTKRLSNRDLQKLEREARICRLLKHSNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEVDASNCMQQILESVSYCHNHNIVHRDLKPENLLLASKTKGAIVKLADFGLAIEV-QGDATAWYGFAGTPGYLSPEVLRKEPYGKAVDIWACGVILYILLVGYPPFWDEDQSKLYGQIKAGAYDYPSPEWDTVTIEAKKLINSMLQVNVSKRISAAEALKNPWICQRDRVASMFHRQQTVDCLRKFNARRKLKGAILTTMLATKNF-------------------------SLAKSITNSTSNQNNTQ----NTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDK-NGS--VTVGRGEETRIWQ-RKEGKWQNIHVHKS 478
[Close]
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Match: SMESG000062800.1 (SMESG000062800.1)

HSP 1 Score: 668.692 bits (1724), Expect = 0.000e+0
Identity = 331/512 (64.65%), Postives = 401/512 (78.32%), Query Frame = 2 
Query:   59 MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSSRDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDIVAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNARVKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACGVILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQMLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLKGAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDSKTPSRVMNCNSTVLKSD-------VSSSEIETKKQEIIKVTEQLISSISACDFNSYTKLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSK-NTKMSHTSILNPTVHLLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIHVHRS 1570
            M     KFSDLYE+K+ELGRGAFSIVK+CVQ ++ LEFAAKIINTKRLS+RD+QKLEREARICRLLKH NIVRLHDSIQD+GFHYLVFDLVTGGELFEDIVAREFYSE DASNCMQQILESV+YCH +NI+HRDLKPENLLL+SK+K A VKLADFGLA+E+ + +  +W GFAGTPGYLSPEVLRK+PYGK VD+WACGVILYILLVGYPPFWDEDQ++LY QIK+G +DYPSPEWDTVT EAK LIN ML VN +KRI+AAEALK+PWI QR+ +ASM HRQQTVDCL+KFNARRKLKGAILTTMLAT+NF                         S+A +I ++  ++  ++    N+ V KSD        ++++ + KKQEI+K+TE L+SSI+  +++S+ KLVD  +T F P++ GNLIEG+D ++F F N  SK + K  + SILNPT+H+LGE+ A IA+V++VQ  D+ NG       + EETRIWQ R   KWQNIHVH+S
Sbjct:    1 MAVTVAKFSDLYELKDELGRGAFSIVKKCVQLSTGLEFAAKIINTKRLSNRDLQKLEREARICRLLKHSNIVRLHDSIQDEGFHYLVFDLVTGGELFEDIVAREFYSEVDASNCMQQILESVSYCHNHNIVHRDLKPENLLLASKTKGAIVKLADFGLAIEV-QGDATAWYGFAGTPGYLSPEVLRKEPYGKAVDIWACGVILYILLVGYPPFWDEDQSKLYGQIKAGAYDYPSPEWDTVTIEAKKLINSMLQVNVSKRISAAEALKNPWICQRDRVASMFHRQQTVDCLRKFNARRKLKGAILTTMLATKNF-------------------------SLAKSITNSTSNQNNTQ----NTIVKKSDKEMIDNISANADCKNKKQEILKLTENLLSSIANGNYSSFIKLVDPQITVFEPDTCGNLIEGIDYYKFLFNNVYSKRDAKSVNMSILNPTIHILGEDCASIAFVKVVQIVDK-NGS--VTVGRGEETRIWQ-RKEGKWQNIHVHKS 478
The following BLAST results are available for this feature:
BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CAMK2D0.000e+067.53calcium/calmodulin dependent protein kinase II del... [more]
CAMK2D0.000e+067.40calcium/calmodulin dependent protein kinase II del... [more]
CAMK2D0.000e+067.33calcium/calmodulin dependent protein kinase II del... [more]
CAMK2D0.000e+067.33calcium/calmodulin dependent protein kinase II del... [more]
CAMK2D0.000e+067.33calcium/calmodulin dependent protein kinase II del... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
unc-430.000e+062.52Calcium/calmodulin-dependent protein kinase type I... [more]
unc-430.000e+062.52Calcium/calmodulin-dependent protein kinase type I... [more]
unc-430.000e+062.52Calcium/calmodulin-dependent protein kinase type I... [more]
unc-430.000e+062.33Calcium/calmodulin-dependent protein kinase type I... [more]
unc-430.000e+062.33Calcium/calmodulin-dependent protein kinase type I... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CaMKII0.000e+069.80gene:FBgn0264607 transcript:FBtr0100147[more]
CaMKII0.000e+069.80gene:FBgn0264607 transcript:FBtr0089219[more]
CaMKII0.000e+069.18gene:FBgn0264607 transcript:FBtr0100148[more]
CaMKII0.000e+067.70gene:FBgn0264607 transcript:FBtr0300378[more]
CaMKII0.000e+067.70gene:FBgn0264607 transcript:FBtr0100146[more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
camk2d20.000e+067.47calcium/calmodulin-dependent protein kinase (CaM k... [more]
camk2b10.000e+062.31calcium/calmodulin-dependent protein kinase (CaM k... [more]
camk2a0.000e+067.07calcium/calmodulin-dependent protein kinase II alp... [more]
camk2d10.000e+065.94calcium/calmodulin-dependent protein kinase (CaM k... [more]
camk2d20.000e+062.75calcium/calmodulin-dependent protein kinase (CaM k... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
atp6v1d0.000e+068.38ATPase, H+ transporting, lysosomal 34kDa, V1 subun... [more]
atp6v1d0.000e+067.73ATPase, H+ transporting, lysosomal 34kDa, V1 subun... [more]
camk2a0.000e+065.95calcium/calmodulin dependent protein kinase (CaM k... [more]
eg435916.10.000e+062.60eg435916, gene 1 [Source:Xenbase;Acc:XB-GENE-92002... [more]
camk2a0.000e+065.12calcium/calmodulin dependent protein kinase (CaM k... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Camk2d0.000e+066.28calcium/calmodulin-dependent protein kinase II, de... [more]
Camk2d0.000e+067.20calcium/calmodulin-dependent protein kinase II, de... [more]
Camk2d0.000e+066.28calcium/calmodulin-dependent protein kinase II, de... [more]
Camk2d0.000e+067.33calcium/calmodulin-dependent protein kinase II, de... [more]
Camk2d0.000e+067.20calcium/calmodulin-dependent protein kinase II, de... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q00168|KCC2A_DROME0.000e+067.70Calcium/calmodulin-dependent protein kinase type I... [more]
sp|O77708|KCC2D_RABIT0.000e+066.28Calcium/calmodulin-dependent protein kinase type I... [more]
sp|Q2HJF7|KCC2D_BOVIN0.000e+067.20Calcium/calmodulin-dependent protein kinase type I... [more]
sp|Q95266|KCC2D_PIG0.000e+066.28Calcium/calmodulin-dependent protein kinase type I... [more]
sp|Q5ZKI0|KCC2D_CHICK0.000e+067.54Calcium/calmodulin-dependent protein kinase type I... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267F0190.000e+070.43Protein kinase domain-containing protein (Fragment... [more]
A0A3Q0KCB80.000e+070.78Protein kinase OS=Schistosoma mansoni OX=6183 PE=4... [more]
A0A504Z1R50.000e+070.70Calcium/calmodulin-dependent protein kinase type I... [more]
A0A4S2LHM90.000e+070.42Protein kinase domain-containing protein OS=Opisth... [more]
A0A267F9630.000e+069.90Protein kinase domain-containing protein OS=Macros... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
camk2b10.000e+063.07calcium/calmodulin-dependent protein kinase type I... [more]
camk2b10.000e+064.45calcium/calmodulin-dependent protein kinase type I... [more]
camk2b20.000e+065.54calcium/calmodulin-dependent protein kinase type I... [more]
camk2g10.000e+062.79calcium/calmodulin-dependent protein kinase type I... [more]
camk2g20.000e+065.01calcium/calmodulin dependent protein kinase II gam... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000008748.10.000e+070.99pep scaffold:Pmarinus_7.0:GL476577:591:63029:-1 ge... [more]
camk2a2.263e-16566.86calcium/calmodulin-dependent protein kinase II alp... [more]
phkg1b7.278e-7139.13phosphorylase kinase, gamma 1b (muscle) [Source:ZF... [more]
RPS6KA35.263e-6438.69ribosomal protein S6 kinase A3 [Source:HGNC Symbol... [more]
ENSPMAT00000003135.13.254e-6040.93pep scaffold:Pmarinus_7.0:GL491838:799:5626:1 gene... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
CMK26.128e-6037.83Calmodulin-dependent protein kinase; may play a ro... [more]
CMK11.031e-5632.58Calmodulin-dependent protein kinase; may play a ro... [more]
SNF18.738e-5140.68AMP-activated S/T protein kinase; forms a complex ... [more]
DUN12.022e-5035.58Cell-cycle checkpoint S/T protein kinase; required... [more]
HSL11.558e-4843.12Nim1p-related protein kinase; septin-binding kinas... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO305370.000e+062.35Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO498980.000e+059.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO330223.151e-8344.52Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO422761.429e-8040.88Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO362539.548e-7542.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000033503.10.000e+065.54calcium/calmodulin-dependent protein kinase type I... [more]
ENSORLT00000046433.10.000e+065.54calcium/calmodulin-dependent protein kinase type I... [more]
camk2d20.000e+065.81calcium/calmodulin-dependent protein kinase type I... [more]
camk2g20.000e+064.61calcium/calmodulin-dependent protein kinase type I... [more]
ENSORLT00000013395.20.000e+062.52calcium/calmodulin-dependent protein kinase type I... [more]
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BLAST of Calcium/calmodulin-dependent protein kinase type II vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000008997.10.000e+0100.00SMESG000008997.1[more]
SMESG000008997.10.000e+098.11SMESG000008997.1[more]
SMESG000029689.10.000e+064.93SMESG000029689.1[more]
SMESG000062800.10.000e+064.65SMESG000062800.1[more]
SMESG000062800.10.000e+064.65SMESG000062800.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025071 ID=SMED30025071|Name=Calcium/calmodulin-dependent protein kinase type II|organism=Schmidtea mediterranea sexual|type=transcript|length=2052bp
AATATCGTGTATGTTGAAATCGTCTAAATAGAATTACTGTAAACTATAAA
TATTTAAAATGGTTACAAATAATGTGAAATTTTCTGATCTTTATGAAATG
AAAGAAGAACTTGGCAGAGGTGCATTTTCAATTGTTAAAAGATGTGTTCA
GAAAGCCTCAAATTTAGAATTCGCAGCAAAAATAATCAATACAAAGAGAT
TATCTTCAAGAGATATGCAAAAATTAGAAAGAGAAGCCAGAATTTGCAGA
CTTTTAAAACATCCTAATATAGTTCGACTTCATGACAGTATTCAAGATGA
TGGATTTCATTATTTAGTATTTGACTTGGTCACAGGAGGAGAACTATTTG
AAGATATTGTAGCTCGCGAATTTTACAGTGAAGCAGATGCAAGCAATTGT
ATGCAACAAATTCTCGAAAGCGTTAATTACTGCCACCAGAATAATATTAT
TCACCGTGACCTCAAGCCCGAAAACCTTTTGTTGTCGAGCAAATCTAAGA
ATGCTAGAGTTAAGTTAGCTGATTTTGGATTAGCCGTTGAAATGAAAGAG
AATGAGGAGGCGTCCTGGCTTGGATTTGCCGGTACTCCTGGTTATTTGTC
TCCAGAGGTTTTACGCAAAGACCCGTATGGTAAACCGGTCGATGTCTGGG
CATGTGGTGTTATTCTGTATATTCTATTGGTTGGTTATCCACCTTTTTGG
GACGAAGATCAGAATCGACTTTATGCCCAAATCAAATCTGGTTTATTTGA
TTATCCGTCACCTGAATGGGATACTGTAACCGCAGAAGCAAAGAATCTCA
TCAATCAAATGTTGACTGTTAATCCCACAAAGAGAATAACAGCTGCAGAG
GCATTGAAACACCCGTGGATTTATCAACGAGAGCACATTGCATCGATGGT
CCATAGACAACAAACTGTGGATTGTCTTAAGAAGTTTAATGCTCGTCGAA
AATTAAAGGGTGCTATTCTAACAACTATGTTGGCCACGAGAAACTTTTCA
AAGTTTTGTTCAAATAGAGATGGATCTTTGATTAGTAAGAAATCCAATGG
CGGAATCAAGGATTCCACAGACAGTGTAGCTCCTGCTATAGAAGATACTG
ATGATTCTAAAACTCCAAGTCGGGTAATGAATTGCAACAGTACGGTGTTG
AAATCAGACGTCAGTTCTTCAGAAATTGAAACGAAGAAGCAGGAGATTAT
CAAAGTCACTGAACAGTTGATCTCCTCTATATCTGCCTGCGATTTCAACT
CATATACTAAACTTGTGGATTCCAATTTAACTTGCTTTGGTCCTGAATCC
ATGGGAAATTTAATAGAAGGAGTTGATATTCATCGATTCTACTTTGAGAA
CGCTTTATCGAAAAATACTAAAATGTCGCATACGAGTATTCTGAATCCAA
CAGTTCATCTGTTAGGCGAAGAAAATGCTTGTATTGCCTATGTAAGACTC
GTTCAGTTTCAAGACCGGTCGAATGGTGGATCTAAATGTCTTACAGAACA
ATTTGAGGAAACCCGAATATGGCAGAAGCGACCAAATAATAAATGGCAGA
ATATCCACGTCCATCGTTCACATCTTGCATTAGAATCCCTGTTGCCGTCA
GTGGCCACTTGTTTTATTGGGAACCAAGCAAAGACCAGTTCATGGATTTG
AAAAAAAAATCGTTTGAACAAAAAAATTATTTGAAATTTTTTTCTGATCA
AGTTATATGATCGAGTTAGCCAATTTTGAGCCAGATAATAATGTTATTCT
CTGATTAGAGATTTTCTCCATGACAAACTTTAAATAGAGTGTCTATGATG
TTTTGTACAACAATAGTATTTCTACTACTGATTCTATCATGTGTGACTGT
GGATTTGTTGAATTCAGGTGTTCAAATTTGAAAACATTTTCCAGATCTGT
TTTTTGTCACAATAGTATCGAGAAAATTTTATTCTTTGAATCCGATTTTC
TATCTTTCTATTCTTAACGATTTATTTAAATATTGATTAAAGCTGTTTGA
TTTGTTTTTAACGTTTATTTTTAGATCAAAAGTATCGATTACTCTAATTT
CA
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protein sequence of SMED30025071-orf-1

>SMED30025071-orf-1 ID=SMED30025071-orf-1|Name=SMED30025071-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=531bp
MVTNNVKFSDLYEMKEELGRGAFSIVKRCVQKASNLEFAAKIINTKRLSS
RDMQKLEREARICRLLKHPNIVRLHDSIQDDGFHYLVFDLVTGGELFEDI
VAREFYSEADASNCMQQILESVNYCHQNNIIHRDLKPENLLLSSKSKNAR
VKLADFGLAVEMKENEEASWLGFAGTPGYLSPEVLRKDPYGKPVDVWACG
VILYILLVGYPPFWDEDQNRLYAQIKSGLFDYPSPEWDTVTAEAKNLINQ
MLTVNPTKRITAAEALKHPWIYQREHIASMVHRQQTVDCLKKFNARRKLK
GAILTTMLATRNFSKFCSNRDGSLISKKSNGGIKDSTDSVAPAIEDTDDS
KTPSRVMNCNSTVLKSDVSSSEIETKKQEIIKVTEQLISSISACDFNSYT
KLVDSNLTCFGPESMGNLIEGVDIHRFYFENALSKNTKMSHTSILNPTVH
LLGEENACIAYVRLVQFQDRSNGGSKCLTEQFEETRIWQKRPNNKWQNIH
VHRSHLALESLLPSVATCFIGNQAKTSSWI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
PLANA:0000099neuron
PLANA:0000418head
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR032710NTF2-like_dom_sf
IPR013543Ca/CaM-dep_prot_kinase-assoc
IPR017441Protein_kinase_ATP_BS
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0005516calmodulin binding
GO:0004683calmodulin-dependent protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0009931calcium-dependent protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
GO:0044325ion channel binding
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0007399nervous system development
GO:0016310phosphorylation
GO:0018105peptidyl-serine phosphorylation
GO:0018107peptidyl-threonine phosphorylation
GO:0030154cell differentiation
GO:0035556intracellular signal transduction
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0030424axon
GO:0042995cell projection
GO:0043005neuron projection
GO:0043204perikaryon
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 12..271
e-value: 2.0E-109
score: 379.5
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 12..271
e-value: 2.4E-76
score: 256.6
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 12..271
score: 52.428
NoneNo IPR availableGENE3DG3DSA:3.30.200.20coord: 1..92
e-value: 9.0E-35
score: 120.9
NoneNo IPR availableGENE3DG3DSA:3.10.450.50coord: 355..506
e-value: 6.9E-52
score: 177.1
NoneNo IPR availableGENE3DG3DSA:1.10.510.10coord: 93..316
e-value: 1.5E-72
score: 245.4
NoneNo IPR availablePANTHERPTHR24347SERINE/THREONINE-PROTEIN KINASEcoord: 361..499
coord: 3..328
NoneNo IPR availablePANTHERPTHR24347:SF403CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT BETAcoord: 361..499
coord: 3..328
NoneNo IPR availableCDDcd14086STKc_CaMKIIcoord: 10..302
e-value: 0.0
score: 631.379
IPR013543Calcium/calmodulin-dependent protein kinase II, association-domainPFAMPF08332CaMKII_ADcoord: 376..505
e-value: 3.8E-45
score: 153.1
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 130..142
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 18..41
IPR011009Protein kinase-like domain superfamilySUPERFAMILYSSF56112Protein kinase-like (PK-like)coord: 12..272
IPR032710NTF2-like domain superfamilySUPERFAMILYSSF54427NTF2-likecoord: 374..504