Endoplasmic reticulum chaperone BiP

Overview


Name	Endoplasmic reticulum chaperone BiP
Smed ID	SMED30025067
Length (bp)	2317

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Endoplasmic reticulum chaperone BiP (SMED30025067) t-SNE clustered cells

Violin plots show distribution of expression levels for Endoplasmic reticulum chaperone BiP (SMED30025067) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Endoplasmic reticulum chaperone BiP (SMED30025067) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Endoplasmic reticulum chaperone BiP (SMED30025067) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025067

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 34

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30025067	h1SMcG0021280	Contig37881	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30025067	h1SMcG0021280	Contig37881	newmark_ests	PMID:29674431 Fincher et al., 2018
pharynx	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cilated neuron	SMED30025067	h1SMcG0021280	dd_Smed_v4_511_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
whole organism	SMED30025067	h1SMcG0021280	Contig50519	newmark_ests	PMID:27612384 Roberts-Galbraith et al., 2016
whole organism	SMED30025067	h1SMcG0021280	Contig50519	uc_Smed_v2	PMID:27612384 Roberts-Galbraith et al., 2016
epidermis	SMED30025067	h1SMcG0009603	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30025067	h1SMcG0009603	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30025067	h1SMcG0009603	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30025067	h1SMcG0009603	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30025067	h1SMcG0009604	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30025067	h1SMcG0009604	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30025067	h1SMcG0009604	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30025067	h1SMcG0009604	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 2 cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
secretory system	SMED30025067	h1SMcG0021280	dd_Smed_v6_511_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
epidermis	SMED30025067	h1SMcG0021280	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
progenitor cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
neoblast	SMED30025067	h1SMcG0021280	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30025067	h1SMcG0021280	dd_Smed_v6_320_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA5 (heat shock protein family A (Hsp70) member 5 [Source:HGNC Symbol;Acc:HGNC:5238])

HSP 1 Score: 965.681 bits (2495), Expect = 0.000e+0
Identity = 488/612 (79.74%), Postives = 552/612 (90.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K  PFKV+ K  KP ++V +G  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES Y+GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKET+ KAV+E I WLE +Q A+ E+FK +KK++E+IV PI++KLY  +G
Sbjct:   28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAG 639

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA8 (heat shock protein family A (Hsp70) member 8 [Source:HGNC Symbol;Acc:HGNC:5241])

HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0
Identity = 395/611 (64.65%), Postives = 488/611 (79.87%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF V+N   +P V+V+   E KSF PEE+S+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+++KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D+K ++KV +KN LE YA+++K  V D EKL  K++  DK+ I+   +E I+WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF V+N   +P V+V+   E KSF PEE+S+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+++KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D+K ++KV +KN LE YA+++K  V D EKL  K++  DK+ I+   +E I+WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF V+N   +P V+V+   E KSF PEE+S+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+++KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D+K ++KV +KN LE YA+++K  V D EKL  K++  DK+ I+   +E I+WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIINWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Match: HSPA2 (heat shock protein family A (Hsp70) member 2 [Source:HGNC Symbol;Acc:HGNC:5235])

HSP 1 Score: 762.296 bits (1967), Expect = 0.000e+0
Identity = 391/613 (63.78%), Postives = 489/613 (79.77%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG---GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXX--XXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NT+FD KR+IGR F D TVQ DMKH+PF+V+++  KP V+V+   E K+F PEEIS+MVL KMK IAEAYLG KV  AV+TVPAYFND+QRQAT DAG I GLNVLRIINEPTAAAIAYGLDKKG   GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ +  + +K+K  KDI  +KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T++PVEK L+DA++ K  I EIVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA+GAAVQA ++     E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQ +V +QVYEGER MTKDN+ LGKFDLTGIP APRGVPQIEVTF+ID NGIL V+A DK TG +NKI I  D+ RL+ +DI++M+++AE Y  +D+  +++V AKN LE Y Y++K  V D EKL  K+S  DK  I+    E I+WL++NQ AE +E++ ++K++E +  PI++KLYQ
Sbjct:    5 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGETKTFFPEEISSMVLTKMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ 615

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Match: hsp-3 (Heat shock 70 kDa protein C [Source:UniProtKB/Swiss-Prot;Acc:P27420])

HSP 1 Score: 956.051 bits (2470), Expect = 0.000e+0
Identity = 498/645 (77.21%), Postives = 574/645 (88.99%), Query Frame = 1

Query:  142 MKSITII-FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTA-EGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MK++ ++  I+L   S+Y  +++K EK + + YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAF+  +G+RLIGDAAKNQLT NPENT+FD KR+IGR++NDKTVQ D+KH+PFKVI+K+NKPSVEV+VG++ K F PEE+SAMVL KMK IAE+YLGK+V +AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H  ++EIESL+DGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KK+D++EIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQ GVI G E+TG+IVLLDV PLT+GIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTG+P APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +A+ DKKVK+K EA+N+LE YAY+LK Q+ DKEKLG KL   DK+TI +AV+EAISWL  N +A  EE K QKK +E  V PI++KLY+ +G
Sbjct:    1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETK-YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644

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Query:  142 MKSITII-FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTA-EGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MK++ ++  I+L   S+Y  +++K EK + + YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAF+  +G+RLIGDAAKNQLT NPENT+FD KR+IGR++NDKTVQ D+KH+PFKVI+K+NKPSVEV+VG++ K F PEE+SAMVL KMK IAE+YLGK+V +AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H  ++EIESL+DGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KK+D++EIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQ GVI G E+TG+IVLLDV PLT+GIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTG+P APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +A+ DKKVK+K EA+N+LE YAY+LK Q+ DKEKLG KL   DK+TI +AV+EAISWL  N +A  EE K QKK +E  V PI++KLY+ +G
Sbjct:    1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETK-YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644

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Query:  142 MKSITII-FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTA-EGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MK++ ++  I+L   S+Y  +++K EK + + YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAF+  +G+RLIGDAAKNQLT NPENT+FD KR+IGR++NDKTVQ D+KH+PFKVI+K+NKPSVEV+VG++ K F PEE+SAMVL KMK IAE+YLGK+V +AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H  ++EIESL+DGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KK+D++EIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQ GVI G E+TG+IVLLDV PLT+GIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTG+P APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +A+ DKKVK+K EA+N+LE YAY+LK Q+ DKEKLG KL   DK+TI +AV+EAISWL  N +A  EE K QKK +E  V PI++KLY+ +G
Sbjct:    1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETK-YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644

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Query:  142 MKSITII-FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTA-EGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MK++ ++  I+L   S+Y  +++K EK + + YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAF+  +G+RLIGDAAKNQLT NPENT+FD KR+IGR++NDKTVQ D+KH+PFKVI+K+NKPSVEV+VG++ K F PEE+SAMVL KMK IAE+YLGK+V +AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H  ++EIESL+DGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KK+D++EIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQ GVI G E+TG+IVLLDV PLT+GIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTG+P APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +A+ DKKVK+K EA+N+LE YAY+LK Q+ DKEKLG KL   DK+TI +AV+EAISWL  N +A  EE K QKK +E  V PI++KLY+ +G
Sbjct:    1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETK-YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644

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Query:  142 MKSITII-FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTA-EGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MK++ ++  I+L   S+Y  +++K EK + + YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAF+  +G+RLIGDAAKNQLT NPENT+FD KR+IGR++NDKTVQ D+KH+PFKVI+K+NKPSVEV+VG++ K F PEE+SAMVL KMK IAE+YLGK+V +AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H  ++EIESL+DGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KK+D++EIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQ GVI G E+TG+IVLLDV PLT+GIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTG+P APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +A+ DKKVK+K EA+N+LE YAY+LK Q+ DKEKLG KL   DK+TI +AV+EAISWL  N +A  EE K QKK +E  V PI++KLY+ +G
Sbjct:    1 MKTLFLLGLIALSAVSVYCEEEEKTEKKETK-YGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFSGDQGDRLIGDAAKNQLTINPENTIFDAKRLIGRDYNDKTVQADIKHWPFKVIDKSNKPSVEVKVGSDNKQFTPEEVSAMVLVKMKEIAESYLGKEVKNAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKDGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDKRAVQKLRREVEKAKRALSTQHQTKVEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKDDVHEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQGGVISGEEDTGEIVLLDVNPLTMGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHQLGKFDLTGLPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFAEDDKKVKDKAEARNELESYAYNLKNQIEDKEKLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073610)

HSP 1 Score: 946.036 bits (2444), Expect = 0.000e+0
Identity = 484/611 (79.21%), Postives = 545/611 (89.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFTA+GERLIGDAAKNQLTTNPENTVFD KR+IGR ++D  VQ D+K FPFKV+ KN+KP + V      K FAPEEISAMVLGKMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGL V+RIINEPTAAAIAYGLDKK GEKN+LVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS +H  RIEIES ++G+DFSETLTRA+FEELN+DLFRST+KPV+KVL+DA+M K+D++EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+ G ++T  IVLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQVFSTA+DNQ TVTIQVYEGERPMTKDNH LGKFDLTGIP APRG+PQIEV+FEID NGIL+VSAEDKGTGNK KI+I  DQNRL  EDI++MI+DAE +AD+DKK+KE+VE++N+LE YAYSLK Q+ DK+KLGAKLS  +K  +  A+DE+I WLE+N  A+ EE+K QKK +E IV P++ KLYQ +G
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAG 639

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0345166)

HSP 1 Score: 946.036 bits (2444), Expect = 0.000e+0
Identity = 484/611 (79.21%), Postives = 545/611 (89.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFTA+GERLIGDAAKNQLTTNPENTVFD KR+IGR ++D  VQ D+K FPFKV+ KN+KP + V      K FAPEEISAMVLGKMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGL V+RIINEPTAAAIAYGLDKK GEKN+LVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS +H  RIEIES ++G+DFSETLTRA+FEELN+DLFRST+KPV+KVL+DA+M K+D++EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+ G ++T  IVLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQVFSTA+DNQ TVTIQVYEGERPMTKDNH LGKFDLTGIP APRG+PQIEV+FEID NGIL+VSAEDKGTGNK KI+I  DQNRL  EDI++MI+DAE +AD+DKK+KE+VE++N+LE YAYSLK Q+ DK+KLGAKLS  +K  +  A+DE+I WLE+N  A+ EE+K QKK +E IV P++ KLYQ +G
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAG 639

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073609)

HSP 1 Score: 946.036 bits (2444), Expect = 0.000e+0
Identity = 484/611 (79.21%), Postives = 545/611 (89.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFTA+GERLIGDAAKNQLTTNPENTVFD KR+IGR ++D  VQ D+K FPFKV+ KN+KP + V      K FAPEEISAMVLGKMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGL V+RIINEPTAAAIAYGLDKK GEKN+LVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS +H  RIEIES ++G+DFSETLTRA+FEELN+DLFRST+KPV+KVL+DA+M K+D++EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+ G ++T  IVLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQVFSTA+DNQ TVTIQVYEGERPMTKDNH LGKFDLTGIP APRG+PQIEV+FEID NGIL+VSAEDKGTGNK KI+I  DQNRL  EDI++MI+DAE +AD+DKK+KE+VE++N+LE YAYSLK Q+ DK+KLGAKLS  +K  +  A+DE+I WLE+N  A+ EE+K QKK +E IV P++ KLYQ +G
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAG 639

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073611)

HSP 1 Score: 946.036 bits (2444), Expect = 0.000e+0
Identity = 484/611 (79.21%), Postives = 545/611 (89.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFTA+GERLIGDAAKNQLTTNPENTVFD KR+IGR ++D  VQ D+K FPFKV+ KN+KP + V      K FAPEEISAMVLGKMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGL V+RIINEPTAAAIAYGLDKK GEKN+LVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS +H  RIEIES ++G+DFSETLTRA+FEELN+DLFRST+KPV+KVL+DA+M K+D++EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+ G ++T  IVLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQVFSTA+DNQ TVTIQVYEGERPMTKDNH LGKFDLTGIP APRG+PQIEV+FEID NGIL+VSAEDKGTGNK KI+I  DQNRL  EDI++MI+DAE +AD+DKK+KE+VE++N+LE YAYSLK Q+ DK+KLGAKLS  +K  +  A+DE+I WLE+N  A+ EE+K QKK +E IV P++ KLYQ +G
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAG 639

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Match: Hsc70-3 (gene:FBgn0001218 transcript:FBtr0073608)

HSP 1 Score: 946.036 bits (2444), Expect = 0.000e+0
Identity = 484/611 (79.21%), Postives = 545/611 (89.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFTA+GERLIGDAAKNQLTTNPENTVFD KR+IGR ++D  VQ D+K FPFKV+ KN+KP + V      K FAPEEISAMVLGKMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGL V+RIINEPTAAAIAYGLDKK GEKN+LVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS +H  RIEIES ++G+DFSETLTRA+FEELN+DLFRST+KPV+KVL+DA+M K+D++EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+ G ++T  IVLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQVFSTA+DNQ TVTIQVYEGERPMTKDNH LGKFDLTGIP APRG+PQIEV+FEID NGIL+VSAEDKGTGNK KI+I  DQNRL  EDI++MI+DAE +AD+DKK+KE+VE++N+LE YAYSLK Q+ DK+KLGAKLS  +K  +  A+DE+I WLE+N  A+ EE+K QKK +E IV P++ KLYQ +G
Sbjct:   29 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTTNPENTVFDAKRLIGREWSDTNVQHDIKFFPFKVVEKNSKPHISVDTSQGAKVFAPEEISAMVLGKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLQVMRIINEPTAAAIAYGLDKKEGEKNVLVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSGSHQVRIEIESFFEGDDFSETLTRAKFEELNLDLFRSTLKPVQKVLEDADMNKKDVHEIVLVGGSTRIPKVQQLVKDFFGGKEPSRGINPDEAVAYGAAVQAGVLSGEQDTDAIVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQVFSTASDNQHTVTIQVYEGERPMTKDNHLLGKFDLTGIPPAPRGIPQIEVSFEIDANGILQVSAEDKGTGNKEKIVITNDQNRLTPEDIDRMIRDAEKFADEDKKLKERVESRNELESYAYSLKNQIGDKDKLGAKLSDDEKNKLESAIDESIKWLEQNPDADPEEYKKQKKDLEAIVQPVIAKLYQGAG 639

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848])

HSP 1 Score: 970.689 bits (2508), Expect = 0.000e+0
Identity = 490/612 (80.07%), Postives = 555/612 (90.69%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR + D +VQ D+K+FPFKVI K NKP +++ +G+ ++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS  H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G EETGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  EDIE+M+ +AE +AD+DKK+KE+++++N+LE YAYSLK Q+ DKEKLG KLS  DKE I KAV+E I WLE +Q A+ EEF+ +KK++E++V PI++KLY  +G
Sbjct:   26 GTVIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKRDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKPDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEETGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNEAERFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWLEAHQDADLEEFQAKKKELEEVVQPIVSKLYGSAG 637

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 782.711 bits (2020), Expect = 0.000e+0
Identity = 396/613 (64.60%), Postives = 489/613 (79.77%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N++P V+V+   E KSF PEEIS+MVL KMK IAEAYLGK V++AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L++++FNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E I WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ +
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVED-EKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSA 614

[Close]

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N++P V+V+   E KSF PEEIS+MVL KMK IAEAYLGK V++AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L++++FNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E I WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ +
Sbjct:    9 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVED-EKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSA 619

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Match: hspa8 (heat shock protein 8 [Source:NCBI gene;Acc:573376])

HSP 1 Score: 782.326 bits (2019), Expect = 0.000e+0
Identity = 396/613 (64.60%), Postives = 489/613 (79.77%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N++P V+V+   E KSF PEEIS+MVL KMK IAEAYLGK V++AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L++++FNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E I WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ +
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVED-EKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSA 614

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N++P V+V+   E KSF PEEIS+MVL KMK IAEAYLGK V++AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L++++FNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E I WL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ +
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDGVVQSDMKHWPFNVINDNSRPKVQVEYKGESKSFYPEEISSMVLTKMKEIAEAYLGKTVSNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDYFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVED-EKLKGKISDEDKQKILDKCNEVIGWLDKNQTAEREEFEHQQKELEKVCNPIITKLYQSA 614

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 970.304 bits (2507), Expect = 0.000e+0
Identity = 499/644 (77.48%), Postives = 570/644 (88.51%), Query Frame = 1

Query:  139 SMKSITIIFISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            +MK   ++   L+  S++AADDD K +      GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI +  KP ++V +G+++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL DA++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q ++ EEFK +KK++E+IV PI+ KLY  +G
Sbjct:    3 TMKLFALVL--LVSASVFAADDDDKRED----VGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIVGKLYGGAG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 969.918 bits (2506), Expect = 0.000e+0
Identity = 495/636 (77.83%), Postives = 565/636 (88.84%), Query Frame = 1

Query:  163 FISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            F+  L+  + A+     +  K+ED GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI +  KP ++V +G+++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL DA++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q ++ EEFK +KK++E+IV PI+ KLY  +G
Sbjct:    6 FLFALVLLVSASVFAADDDDKREDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIVGKLYGGAG 641

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 968.763 bits (2503), Expect = 0.000e+0
Identity = 499/640 (77.97%), Postives = 569/640 (88.91%), Query Frame = 1

Query:  154 TIIFISLLI-CSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            T+  + LL+  S++AADDD K +      GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI +  KP ++V +G+++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL DA++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q ++ EEFK +KK++E+IV PI+ KLY  +G
Sbjct:    5 TLFALVLLVSASVFAADDDDKRED----VGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIVGKLYGGAG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 967.992 bits (2501), Expect = 0.000e+0
Identity = 489/611 (80.03%), Postives = 553/611 (90.51%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI +  KP ++V +G+++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL DA++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q ++ EEFK +KK++E+IV PI+ KLY  +G
Sbjct:   30 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDSDIEEFKAKKKELEEIVQPIVGKLYGGAG 640

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Match: nsg1 (neuronal vesicle trafficking associated 1 [Source:Xenbase;Acc:XB-GENE-992527])

HSP 1 Score: 923.694 bits (2386), Expect = 0.000e+0
Identity = 477/602 (79.24%), Postives = 538/602 (89.37%), Query Frame = 1

Query:  139 SMKSITIIFISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKA 1944
            +MK   ++   L+  S++AADDD K +      GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI +  KP ++V +G+++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL DA++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KA
Sbjct:    3 TMKLFALVL--LVSASVFAADDDDKRED----VGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIERKTKPYIQVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDADLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKA 598

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa5 (heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95835])

HSP 1 Score: 962.214 bits (2486), Expect = 0.000e+0
Identity = 487/612 (79.58%), Postives = 551/612 (90.03%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K  PFKV+ K  KP ++V +G  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKET+ KAV+E I WLE +Q A+ E+FK +KK++E+IV PI++KLY   G
Sbjct:   29 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGG 640

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K  PFKV+ K  KP ++V +G  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKET+ KAV+E I WLE +Q A+ E+FK +KK++E+IV PI++KLY   G
Sbjct:   29 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa8 (heat shock protein 8 [Source:MGI Symbol;Acc:MGI:105384])

HSP 1 Score: 784.252 bits (2024), Expect = 0.000e+0
Identity = 396/611 (64.81%), Postives = 488/611 (79.87%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF V+N   +P V+V+   E KSF PEE+S+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+++KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D+K ++KV +KN LE YA+++K  V D EKL  K++  DK+ I+   +E ISWL+KNQ AE EEF+ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFMVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLTKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVED-EKLQGKINDEDKQKILDKCNEIISWLDKNQTAEKEEFEHQQKELEKVCNPIITKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Match: Hspa2 (heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96243])

HSP 1 Score: 761.911 bits (1966), Expect = 0.000e+0
Identity = 390/613 (63.62%), Postives = 490/613 (79.93%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG---GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXX--XXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NT+FD KR+IGR F D TVQ DMKH+PF+V+++  KP V+V+   E+K+F PEEIS+MVL KMK IAEAYLG KV  AV+TVPAYFND+QRQAT DAG I GLNVLRIINEPTAAAIAYGLDKKG   GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ +  + +K+K  KDI  +KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T++PVEK L+DA++ K  I EIVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA+GAAVQA ++     E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQ +V +QVYEGER MTKDN+ LGKFDLTGIP APRGVPQIEVTF+ID NGIL V+A DK TG +NKI I  D+ RL+ +DI++M+++AE Y  +D+  +++V AKN +E Y Y++K  V D EKL  K+S  DK  I+    E I+WL++NQ AE +E++ ++K++E +  PI++KLYQ
Sbjct:    5 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ 615

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG---GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXX--XXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NT+FD KR+IGR F D TVQ DMKH+PF+V+++  KP V+V+   E+K+F PEEIS+MVL KMK IAEAYLG KV  AV+TVPAYFND+QRQAT DAG I GLNVLRIINEPTAAAIAYGLDKKG   GEKN+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++ +  + +K+K  KDI  +KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T++PVEK L+DA++ K  I EIVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA+GAAVQA ++     E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQ +V +QVYEGER MTKDN+ LGKFDLTGIP APRGVPQIEVTF+ID NGIL V+A DK TG +NKI I  D+ RL+ +DI++M+++AE Y  +D+  +++V AKN +E Y Y++K  V D EKL  K+S  DK  I+    E I+WL++NQ AE +E++ ++K++E +  PI++KLYQ
Sbjct:    5 GPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEMKTFFPEEISSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVAAKNAVESYTYNIKQTVED-EKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQKELERVCNPIISKLYQ 615

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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q16956|BIP_APLCA (Endoplasmic reticulum chaperone BiP OS=Aplysia californica OX=6500 PE=1 SV=1)

HSP 1 Score: 982.245 bits (2538), Expect = 0.000e+0
Identity = 503/611 (82.32%), Postives = 558/611 (91.33%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGVFK GRV+IIANDQGNRITPSYVAFTA+GERLIGDAAKNQLT+NPENT+FDVKR+IGR F+DK+VQ D+K +PFKV N NNKP ++   G   +SFAPEEISAMVL KM+ IAE YLGKK+T+AVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV++TNGDTHLGGEDFDQRVM +FIKLYKKKKGKDI  D RAVQKLRREVEKAKRALS+AH  R+EIES +DGEDFSE+LTRA+FEELNMDLFRSTMKPV++VL+DA++K +DI+EIVLVGGSTRIPKVQQLVKE+FNGKEPSRGINPDEAVA+GAAVQAGV+ G E+TGD+VLLDV PLT+GIETVGGVMTKLIPRNTVIPTKKSQ+FSTAADNQPTVTIQVYEGER MTKDNH LGKFDLTGIP APRGVPQIEVTFEIDVNGILKV+AEDKGTG+KN+I+IQ DQNRL+ EDIE+MI DAE YAD+DKKVKEKV+AKN+LE YAYSLK Q+ DKEKLGAKLS  DKE I +AVDEAI WLE N +AE+E F  +K ++E IV PIMTKLY+QSG
Sbjct:   38 GTVIGIDLGTTYSCVGVFKNGRVDIIANDQGNRITPSYVAFTADGERLIGDAAKNQLTSNPENTIFDVKRLIGRTFDDKSVQHDIKFYPFKVTNANNKPHIQAATGEGDRSFAPEEISAMVLSKMRDIAEEYLGKKITNAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVSTNGDTHLGGEDFDQRVMEHFIKLYKKKKGKDIRKDNRAVQKLRREVEKAKRALSSAHQVRLEIESFFDGEDFSESLTRAKFEELNMDLFRSTMKPVKQVLEDADLKTDDIDEIVLVGGSTRIPKVQQLVKEYFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDLVLLDVNPLTMGIETVGGVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERSMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILKVTAEDKGTGSKNQIVIQNDQNRLSPEDIERMINDAEKYADEDKKVKEKVDAKNELESYAYSLKNQIGDKEKLGAKLSDEDKEKITEAVDEAIKWLESNAEAESEAFNEKKTELEGIVQPIMTKLYEQSG 648

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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q90593|BIP_CHICK (Endoplasmic reticulum chaperone BiP OS=Gallus gallus OX=9031 GN=HSPA5 PE=1 SV=1)

HSP 1 Score: 967.222 bits (2499), Expect = 0.000e+0
Identity = 489/612 (79.90%), Postives = 554/612 (90.52%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKV+ K  KP ++V VG  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++A+N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q A+ E+FK +KK++E++V PI++KLY  +G
Sbjct:   26 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVVEKKAKPHIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDARNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDADIEDFKSKKKELEEVVQPIVSKLYGSAG 637

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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q0VCX2|BIP_BOVIN (Endoplasmic reticulum chaperone BiP OS=Bos taurus OX=9913 GN=HSPA5 PE=2 SV=1)

HSP 1 Score: 966.452 bits (2497), Expect = 0.000e+0
Identity = 489/612 (79.90%), Postives = 552/612 (90.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K  PFKV+ K  KP ++V VG  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES Y+GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKET+ KAV+E I WLE +Q A+ E+FK +KK++E+IV PI++KLY  +G
Sbjct:   29 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|Q91883|BIP_XENLA (Endoplasmic reticulum chaperone BiP OS=Xenopus laevis OX=8355 GN=hspa5 PE=2 SV=1)

HSP 1 Score: 965.681 bits (2495), Expect = 0.000e+0
Identity = 489/611 (80.03%), Postives = 552/611 (90.34%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K+ PFKVI K  KP +EV +G+++K+FAPEEISAMVL KMK  AEAYLG+KVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  DKRAVQKLRREVEKAKRALS  H +RIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL D+++KK DI+EIVLVGGSTRIPK+QQLVKE FNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I WLE +Q A+ E+FK +KK++E+IV PI+ KLY  +G
Sbjct:   30 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKYLPFKVIEKKTKPYIEVDIGDQMKTFAPEEISAMVLVKMKETAEAYLGRKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRADKRAVQKLRREVEKAKRALSAQHQSRIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLDDSDLKKSDIDEIVLVGGSTRIPKIQQLVKELFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVTDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETIEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIVGKLYGGAG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Match: sp|P06761|BIP_RAT (Endoplasmic reticulum chaperone BiP OS=Rattus norvegicus OX=10116 GN=Hspa5 PE=1 SV=1)

HSP 1 Score: 965.681 bits (2495), Expect = 0.000e+0
Identity = 488/612 (79.74%), Postives = 552/612 (90.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGDAAKNQLT+NPENTVFD KR+IGR +ND +VQ D+K  PFKV+ K  KP ++V +G  + K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDK+ GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK DI+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G ++TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +A++DKK+KE+++ +N+LE YAYSLK Q+ DKEKLG KLSP DKET+ KAV+E I WLE +Q A+ E+FK +KK++E+IV PI++KLY   G
Sbjct:   28 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGG 639

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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: G8JF14 (Glucose-regulated protein 78 OS=Dugesia japonica OX=6161 GN=grp78 PE=2 SV=2)

HSP 1 Score: 1157.13 bits (2992), Expect = 0.000e+0
Identity = 608/643 (94.56%), Postives = 629/643 (97.82%), Query Frame = 1

Query:  142 MKSITIIFISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MKSIT++ ISLL+C IYAA +++KEKTKKEDYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITP YVAFT+EG+RLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQ+DMKHFPFKV+NKNNKPSVEVQVG+E K+FAPEEISAMVLGKM+ IAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAG IAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVM YF+KLYKKKKGKDI+DDKRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQV+EGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKI+IQKDQNRLNTEDIEKMIKDAETYADQDKKVKE+VEAKNDLEGYAYSLKTQ+NDKEKLG KLSPSDKE I KA +EAISWLEKNQQA+TEE K QKKKVEDIVTPIMTKLYQQSG
Sbjct:    1 MKSITVLLISLLVCGIYAAGEEEKEKTKKEDYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPPYVAFTSEGDRLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQEDMKHFPFKVVNKNNKPSVEVQVGSETKTFAPEEISAMVLGKMRTIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGTIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMSYFMKLYKKKKGKDISDDKRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVFEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIVIQKDQNRLNTEDIEKMIKDAETYADQDKKVKERVEAKNDLEGYAYSLKTQINDKEKLGGKLSPSDKEIITKAAEEAISWLEKNQQADTEEMKAQKKKVEDIVTPIMTKLYQQSG 643

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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A1I8HNI7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g1 PE=3 SV=1)

HSP 1 Score: 1021.54 bits (2640), Expect = 0.000e+0
Identity = 528/650 (81.23%), Postives = 596/650 (91.69%), Query Frame = 1

Query:  118 LIRNLFESMKSITIIFISLLIC---SIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            L+ +  +++ +  + ++++L+C   ++  +D +K ++ KKED GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLTTNPENT+FDVKRIIGRN+ D  VQ D+K  P+ V+NKN+KP+++VQVG+E K+FAPEEISAMVLGKMK IAE+YLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKKKGKD+  D RAVQKLRREVEKAKRALS+AH+AR+EIESLYDGEDFSETLTRARFEELNMDLFRSTMKPV+KVL+DA++KKEDI EIVLVGGSTRIPKVQQLVKEFF+GKEP+RGINPDEAVA+GAAVQAGV+GG E+TGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIP APRGVPQIEVTFEID NGIL+VSAEDKGTGNKNKI+I KDQNRL+ ++IEKMIKDA+T+ADQDKKVKE+VEAKN+LE YAYS+KTQ+ DKEKLG K+S  +K  + KA+  AI WLEKNQQA+TE  K QKK++E +V PI++KLY
Sbjct:    1 LLNSQTQTIMNKQLFYLAMLVCIGLALADSDKEKTDQKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSETKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYFIKLYKKKKGKDLRTDNRAVQKLRREVEKAKRALSSAHTARVEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVQKVLEDADLKKEDIAEIVLVGGSTRIPKVQQLVKEFFSGKEPNRGINPDEAVAYGAAVQAGVLGGAEDTGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPNAPRGVPQIEVTFEIDANGILQVSAEDKGTGNKNKIVINKDQNRLSPDEIEKMIKDADTFADQDKKVKERVEAKNELESYAYSMKTQLADKEKLGGKVSADEKAKMEKAIQAAIDWLEKNQQADTEALKEQKKELEAVVQPIVSKLY 650

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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A1I8H5I1 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g3 PE=3 SV=1)

HSP 1 Score: 1021.54 bits (2640), Expect = 0.000e+0
Identity = 529/641 (82.53%), Postives = 589/641 (91.89%), Query Frame = 1

Query:  157 IIFISLLIC-------SIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            + ++++L+C       S  +AD +K ++ KKED GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLTTNPENT+FDVKRIIGRN+ D  VQ D+K  P+ V+NKN+KP+++VQVG+E K+FAPEEISAMVLGKMK IAE+YLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKKKGKD+  D RAVQKLRREVEKAKRALS+AH+AR+EIESLYDGEDFSETLTRARFEELNMDLFRSTMKPV+KVL+DA++KKEDI EIVLVGGSTRIPKVQQLVKEFF+GKEP+RGINPDEAVA+GAAVQAGV+GG E+TGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIP APRGVPQIEVTFEID NGIL+VSAEDKGTGNKNKI+I KDQNRL+ ++IEKMIKDA+T+ADQDKKVKE+VEAKN+LE YAYS+KTQ+ DKEKLG K+S  +K  + KA+  AI WLEKNQQA+TE  K QKK++E +V PI++KLY
Sbjct:   14 LFYLAMLVCIGLALADSDKSADKEKTDQKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSEAKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYFIKLYKKKKGKDLRTDNRAVQKLRREVEKAKRALSSAHTARVEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVQKVLEDADLKKEDIAEIVLVGGSTRIPKVQQLVKEFFSGKEPNRGINPDEAVAYGAAVQAGVLGGAEDTGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPNAPRGVPQIEVTFEIDANGILQVSAEDKGTGNKNKIVINKDQNRLSPDEIEKMIKDADTFADQDKKVKERVEAKNELESYAYSMKTQLADKEKLGGKVSADEKAKMEKAIQAAIDWLEKNQQADTEALKEQKKELEAVVQPIVSKLY 654

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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A267GFX2 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig032526g2 PE=3 SV=1)

HSP 1 Score: 1021.15 bits (2639), Expect = 0.000e+0
Identity = 527/637 (82.73%), Postives = 589/637 (92.46%), Query Frame = 1

Query:  157 IIFISLLIC---SIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            + ++++L+C   ++  +D +K ++ KKED GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLTTNPENT+FDVKRIIGRN+ D  VQ D+K  P+ V+NKN+KP+++VQVG+E K+FAPEEISAMVLGKMK IAE+YLGKKVTHAVVTVPAYFNDAQRQAT DAG+IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLYKKKKGKD+  D RAVQKLRREVEKAKRALS+AH+AR+EIESLYDGEDFSETLTRARFEELNMDLFRSTMKPV+KVL+DA++KKEDI EIVLVGGSTRIPKVQQLVKEFF+GKEP+RGINPDEAVA+GAAVQAGV+GG E+TGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIP APRGVPQIEVTFEID NGIL+VSAEDKGTGNKNKI+I KDQNRL+ ++IEKMIKDA+T+ADQDKKVKE+VEAKN+LE YAYS+KTQ+ DKEKLG K+S  +K  + KA+  AI WLEKNQQA+TE  K QKK++E +V PI++KLY
Sbjct:   14 LFYLAMLVCIGLALADSDKEKTDQKKKEDVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTTNPENTIFDVKRIIGRNYADDVVQKDIKLLPYTVVNKNSKPAIQVQVGSEAKTFAPEEISAMVLGKMKEIAESYLGKKVTHAVVTVPAYFNDAQRQATKDAGVIAGLNVMRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEYFIKLYKKKKGKDLRTDNRAVQKLRREVEKAKRALSSAHTARVEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVQKVLEDADLKKEDIAEIVLVGGSTRIPKVQQLVKEFFSGKEPNRGINPDEAVAYGAAVQAGVLGGAEDTGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPNAPRGVPQIEVTFEIDANGILQVSAEDKGTGNKNKIVINKDQNRLSPDEIEKMIKDADTFADQDKKVKERVEAKNELESYAYSMKTQLADKEKLGGKVSADEKAKMEKAIQAAIDWLEKNQQADTEALKEQKKELEAVVQPIVSKLY 650

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BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Match: A0A0N5AHC4 (Uncharacterized protein OS=Syphacia muris OX=451379 PE=3 SV=1)

HSP 1 Score: 986.867 bits (2550), Expect = 0.000e+0
Identity = 509/638 (79.78%), Postives = 571/638 (89.50%), Query Frame = 1

Query:  166 ISLLICSI--YAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAE-GERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            + LL+C++   A     KE+  +  YGT+IGIDLGTTYSCVGV+K GRVEIIANDQGNRITPSYVAFT++ GERLIGDAAKNQLT NPENTVFD KR+IGR++ND+TVQDDMK +PFK++NKNNKP V+++V  E K+FAPEEISAMVLGKMK IAEAYLGK+V HAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GE+NILVFDLGGGTFDVS+LTIDNGVFEV+ATNGDTHLGGEDFDQRV+ YFIKLYKKK GKDI  D RAVQKLRREVEKAKRALS  H  R+E+ESLYDGEDFSETLTRA+FEELNMDLFR+T+KPV+KVL+D+++KKED+NEIVLVGGSTRIPKVQQL+KEFFNGKEPSRGINPDEAVA+GAAVQAGVI G E TGDIVLLDV PLTLGIETVGGVMTKLI RNTVIPTKKSQ+FSTAADNQPTVTIQVYEGERPMTKDNH LGKFDLTGIP APRGVPQIEVTFEIDVNGIL V+AEDKGTGNKNKI I  DQNRL+ EDIE+MI DAE +AD+DKKVKE+VEA+N+LE Y+YSLK Q+NDKEKLG KL  SDK+TI +AVDEAISWL+ ++ A  EE + QKK +E  V PI++KLY+ +G
Sbjct:    3 LWLLLCAVGVLALSAFSKEEKSETKYGTIIGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTSDSGERLIGDAAKNQLTINPENTVFDAKRLIGRDYNDRTVQDDMKVWPFKLVNKNNKPMVQMKVAKESKTFAPEEISAMVLGKMKEIAEAYLGKEVKHAVVTVPAYFNDAQRQATKDAGTIAGLNVVRIINEPTAAAIAYGLDKKEGERNILVFDLGGGTFDVSMLTIDNGVFEVLATNGDTHLGGEDFDQRVIEYFIKLYKKKTGKDIRKDTRAVQKLRREVEKAKRALSTQHQVRVEVESLYDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDSDLKKEDVNEIVLVGGSTRIPKVQQLIKEFFNGKEPSRGINPDEAVAYGAAVQAGVISGEESTGDIVLLDVNPLTLGIETVGGVMTKLITRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHILGKFDLTGIPPAPRGVPQIEVTFEIDVNGILHVTAEDKGTGNKNKITITNDQNRLSPEDIERMINDAEKFADEDKKVKEQVEARNELESYSYSLKNQINDKEKLGGKLDESDKKTIEEAVDEAISWLDSHKDASAEELQEQKKDLEGKVQPIISKLYKDAG 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:103030781])

HSP 1 Score: 971.074 bits (2509), Expect = 0.000e+0
Identity = 490/608 (80.59%), Postives = 554/608 (91.12%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVG-NEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            GTV+GIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLT+NPENTVFD KR+IGR + D +VQ D+K+FPFKV+ K +KP ++V +G  ++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS+ H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK +INEIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G E+TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  EDIE+M+ DAE +AD+DKK+KE+++++N+LE YAYSLK QV DKEKLG KLS  DKE I KAV+E I WLE +Q A+ EEF+ +KK++E++V PI++KLY
Sbjct:   26 GTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWGDSSVQQDVKYFPFKVLEKKSKPHIQVDIGAGQLKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEINEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKKLKERIDSRNELESYAYSLKNQVGDKEKLGGKLSDEDKEAIEKAVEEKIEWLESHQDADLEEFQAKKKELEEVVQPIISKLY 633

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8 (heat shock cognate 71 kDa protein [Source:NCBI gene;Acc:103043364])

HSP 1 Score: 781.556 bits (2017), Expect = 0.000e+0
Identity = 395/613 (64.44%), Postives = 488/613 (79.61%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NT+FD KR+IGR F+D  VQ DMKH+PF VIN + +P V+V    E KSF PEEIS+MVL KMK IAEAYLGK VT+AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV +KN LE YA+++K+ V D EKL  K+S  DK+ I+   +E ISWL+KNQ AE +EF+ Q+K++E +  PI+TKLYQ +
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFDDGVVQSDMKHWPFTVINDSTRPKVQVDYKGEAKSFYPEEISSMVLVKMKEIAEAYLGKTVTNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAADKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSSKNSLESYAFNMKSTVED-EKLKGKISDEDKQKIMDKCNEVISWLDKNQTAERDEFEHQQKELEKVCNPIITKLYQSA 614

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hspa8b (heat shock cognate 70 kDa protein-like [Source:NCBI gene;Acc:103047344])

HSP 1 Score: 780.015 bits (2013), Expect = 0.000e+0
Identity = 396/611 (64.81%), Postives = 488/611 (79.87%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN + +P V+V+   E K+F PEEIS+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ E+IE+M++DAE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E ISWL+KNQ AE +EF+ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDAVVQSDMKHWPFTVINDSTRPKVQVEYKGETKAFYPEEISSMVLVKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFISEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILAGDKSENVQDLLLLDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEEIERMVQDAEKYKAEDDVQRDKVAAKNGLESYAFNMKSTVED-EKLKGKISDEDKQKILDKCNEVISWLDKNQTAEKDEFEHQQKELEKVCNPIITKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: ENSAMXT00000004733.2 (pep primary_assembly:Astyanax_mexicanus-2.0:20:27541457:27560661:-1 gene:ENSAMXG00000004628.2 transcript:ENSAMXT00000004733.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 775.778 bits (2002), Expect = 0.000e+0
Identity = 391/611 (63.99%), Postives = 487/611 (79.71%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            GT +GIDLGTTYSCVG+F+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NT+FD KR+IGR F D  VQ DMKH+PFKVI+   +P VEV+   E K+F PEEIS+MVL KMK IAEAYLGK + +AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV +KN LE YA+++K+ V D +KL  K+S  DK+ I+   +E ISWL+KNQ AE EE++ Q++++E +  PI+TKLYQ
Sbjct:    4 GTAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTIFDAKRLIGRRFEDTVVQSDMKHWPFKVISDGGRPKVEVEYKGETKNFYPEEISSMVLVKMKEIAEAYLGKSINNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTALIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSSKNSLESYAFNMKSTVED-DKLQGKISDEDKQKILDKCNEIISWLDKNQTAEKEEYEHQQQELEKVCNPIITKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Match: hsc70 (heat shock cognate 71 kDa protein-like [Source:NCBI gene;Acc:103045816])

HSP 1 Score: 775.778 bits (2002), Expect = 0.000e+0
Identity = 391/611 (63.99%), Postives = 490/611 (80.20%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVG+F+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PFKV++   KP +EV+   E+K+F PEE+S+MVL KMK I+EAYLGK VT+AV+TVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK GGE+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDIT +KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++FFNG++ ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++A+ Y  +D+  +EKV +KN LE  A+++K+ V D EKL  K+S  DK+TIV   +E I+WL++NQ AE EE++ Q+K++E +  PI+TKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTVFDAKRLIGRRFDDAVVQSDMKHWPFKVVSDGGKPKMEVEYKGEIKTFYPEEVSSMVLTKMKEISEAYLGKPVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNSDLFRGTLDPVEKALRDAKLDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEADQYRAEDEAQREKVTSKNTLESLAFNMKSTVED-EKLKDKISAEDKKTIVDKCNEVIAWLDRNQTAEKEEYEHQQKELEKVCNPIITKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa5 (heat shock protein 5 [Source:NCBI gene;Acc:378848])

HSP 1 Score: 968.378 bits (2502), Expect = 0.000e+0
Identity = 492/608 (80.92%), Postives = 551/608 (90.62%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQV-GNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLT+NPENTVFD KR+IGR++ D TVQ D+K +PF V+ K  KP ++V+V   E K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTID+GVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKR LS  H ARI+IES YDG+DFSETLTRA+FEELNMDLFRSTMKPV+KV++D+++KK DI+EIVLVGGSTRIPK+QQLVKE FNGKEPSRGINPDEAVA+GAAVQAGV+ G + TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTAADNQPTVTIQV+EGERPMTKDNH LGKFDLTGIP APRGVPQIEVTFEIDVNGIL+VSAEDKGTGNKNKI I  DQNRL  E+IE+M+ DAE +AD DK+VKE+VEA+N+LE YAYSLK Q+ DKEKLG KLS  D+ET+ KAV++ I+WLE +Q+A+T++FK QKK++E++V PI++KLY
Sbjct:   33 GTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWTDPTVQHDIKFWPFTVLEKKGKPHIQVEVIAGESKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDHGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDHRAVQKLRREVEKAKRTLSTQHQARIDIESFYDGDDFSETLTRAKFEELNMDLFRSTMKPVQKVMEDSDLKKTDIDEIVLVGGSTRIPKIQQLVKELFNGKEPSRGINPDEAVAYGAAVQAGVLSGEDNTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTAADNQPTVTIQVFEGERPMTKDNHLLGKFDLTGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGNKNKITITNDQNRLTPEEIERMVSDAERFADDDKRVKERVEARNELESYAYSLKNQIGDKEKLGGKLSDEDRETVEKAVEDKIAWLEGHQEADTDDFKAQKKELEEVVQPIVSKLY 640

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa9 (heat shock protein 9 [Source:ZFIN;Acc:ZDB-GENE-030828-12])

HSP 1 Score: 550.051 bits (1416), Expect = 0.000e+0
Identity = 316/614 (51.47%), Postives = 423/614 (68.89%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESL----YDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVND-KEKLGAKLSPSDKETIVK--------------AVDEAISWLEKNQQAETEEFKVQKKKV 2022
            G VIGIDLGTT SCV V +G + +++ N +G R TPS VAFTA+GERL+G  AK Q  TNP NT +  KR+IGR F+D  VQ DM +  +K++  +N    +  V    K ++P +I A VL KMK  AE ++G  V +AV+TVPAYFND+QRQAT DAG I+GLNVLR+INEPTAAA+AYGLDK   +K I V+DLGGGTFD+S+L I  GVFEV +TNGDT LGGEDFD  ++ Y +K +K++ G D+T D  A+Q++R   EKAK  LS++    I +  L       +  +  LTR++FE +  DL R T+ P +K LQD E+ K DI +++LVGG TR+PKVQQ V+E F G+ PS+ +NPDEAVA GAA+Q GV+ G  +  D++LLDV PL+LGIET+GGV TKLI RNT IPTKKSQVFSTAAD Q  V I+V++GER M  DN  LG+F L G+P APRGVPQIEVTF+ID NGI+ VSA+DKGTG + +I+IQ     L+ ++IE M+K+AE YA++D++ K++VEA N  EG  + +++++ + K++L A      KE I K              A+ +A S L   QQ+  + F++  KK+
Sbjct:   53 GAVIGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRFDDSDVQKDMNNLSYKIVRASNG---DAWVEAHGKMYSPSQIGAFVLLKMKETAENFMGTSVKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDK-ADDKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDNALLKYIVKEFKRESGVDLTKDSMALQRVREAAEKAKCELSSSLQTDINLPYLTMDSSGPKHLNMKLTRSQFENIVGDLIRKTIAPCQKALQDGEVAKSDIGDVILVGGMTRMPKVQQTVQEVF-GRAPSKAVNPDEAVAIGAAIQGGVLAG--DVTDVLLLDVTPLSLGIETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVFQGEREMAGDNKNLGQFTLVGVPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGG-LSKDEIENMVKNAEKYAEEDRRRKDRVEAVNQAEGIVHDIESKMEEFKDQLPADECTKLKEEIAKVRELLTRKDTETGEAIKQAASTL---QQSSLKLFEMAYKKM 655

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa14 (heat shock protein 14 [Source:NCBI gene;Acc:565232])

HSP 1 Score: 246.514 bits (628), Expect = 2.702e-73
Identity = 164/518 (31.66%), Postives = 258/518 (49.81%), Query Frame = 1

Query:  247 IGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEK--NILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVC---PLTLGIETVG-------------GVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHF----LGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQ 1734
            +G+ LG+T +CV ++K GR ++IAND G+R+TP+ VAF  + E+++G AAK     N   TV  VKRI+G  F D  VQ  +      VI K+  P   +  G   K     E++ ++L KMK  A   +G     AV+T P  F   Q      A   AG NVLRI++EP AA +A+G+ ++       +LV+ LGG     + + +++G++ V+ +  D  +GGE+F + +  Y    ++K   +D+  + RA+ KL    E AK  LS    +   ++SL+DG DF   +TRARF+ L   LF+ +++P+  +L    +   D  ++VL GGS RIPK+QQL++E F G E    I  DE +A GAA          E G ++  D     P  L IE                   T + P  T +P ++   F  A    P+V + VYEG   + K + F    L +  L  +     G+  I   F +  +G L ++  D+ +G    + ++
Sbjct:    4 VGVHLGSTCACVAIYKDGRADVIANDAGDRVTPAMVAFR-DSEKIVGLAAKQGRIRNATTTVVGVKRILGHRFEDDVVQKYISSSSCPVIEKDGCPVFSINNGTVKKHITRHEVATLILQKMKETALFAVGADAKDAVITTPLNFTTQQVDELRQAAESAGFNVLRILSEPAAALLAFGIGQESSHSKCKVLVYKLGGTCAYATAIEVNSGLYRVLGSVSDDTVGGEEFTEALAEYLATEFQKFHRQDLRGNSRAMMKLHTNAEMAKHVLSTMAISNCFVDSLHDGLDFECNITRARFDSLCSVLFQQSLQPIHDLLAQINLTTSDFQKVVLCGGSARIPKLQQLLQEQFVGSELMCSIPVDEVIALGAAA---------EAGILLGRDAVRFEPEALSIECASLDILVKEQDEAGQDCYTVVFPVGTPLPARRQHTFQ-APGTLPSVLVDVYEG---VAKGSSFEGVHLAQLVLKDLQQQDNGLRDISTVFTMKRDGSLLITCTDQLSGTSETVTVE 507

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Match: hspa13 (heat shock protein 70 family, member 13 [Source:ZFIN;Acc:ZDB-GENE-070410-58])

HSP 1 Score: 242.662 bits (618), Expect = 3.359e-72
Identity = 141/406 (34.73%), Postives = 221/406 (54.43%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGG--RVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQ-VGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARI------------------------------------------EIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPD 1326
            ++GIDLGTTY  +GV+  G   VE++A+  G R  PS VA  ++G  L G  A  Q   NP  T++D KR IGR F+   ++ +   + F V   + +    ++  G   ++  PE + A +L +++++AE  LG  V +AV+ VPA F++ QR +T  A  +AGL VLR++NEPTAAA+AYGL ++    ++LV DLGGGT DVSLLT   G+F   A  G+ HLGG+DF QR++ +       + G      +   Q LR   E AK  L++   AR+                                          +++  ++  +  ET+TR  FE LN DLF+  M+P+ +VL+   +  + ++ +VLVGGSTRIP+V++++ ++F G EP   ++P+
Sbjct:   33 IVGIDLGTTYCSIGVYHAGVGEVEVLADADGRRAFPSVVAAGSDGRVLAGFPALQQAADNPHATLYDAKRFIGRAFSPGELEREAGRYQFTVRQVSGEVVFVLRGHGGAEQTVTPEWVGAQMLDQLRLLAEERLGLPVRYAVLAVPAEFDERQRNSTIKAATMAGLEVLRVVNEPTAAALAYGLHEEESVSSVLVVDLGGGTTDVSLLTKQGGMFFTRAMAGNNHLGGQDFTQRLVEHLTGRLADRHGGGRPWGRADTQLLREAAEMAKLELTHNDRARVSLRLSLVFMPDNRPCCVHQETTVYIRRPLCTGGNAHVLFFGLKLKGTHNTVEMDETVTRQEFESLNEDLFQKVMEPIVEVLRSGRLVAKQVDRVVLVGGSTRIPRVRRMLADYF-GSEPDTSVDPE 437

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: KAR2 (ATPase involved in protein import into the ER; also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p [Source:SGD;Acc:S000003571])

HSP 1 Score: 783.097 bits (2021), Expect = 0.000e+0
Identity = 407/609 (66.83%), Postives = 493/609 (80.95%), Query Frame = 1

Query:  235 YGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKN-QQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            YGTVIGIDLGTTYSCV V K G+ EI+AN+QGNRITPSYVAFT + ERLIGDAAKNQ+  NP+NT+FD+KR+IG  +ND++VQ D+KH PF V+NK+ KP+VEV V  E K F PEEIS M+LGKMK IAE YLG KVTHAVVTVPAYFNDAQRQAT DAG IAGLNVLRI+NEPTAAAIAYGLDK   E  I+V+DLGGGTFDVSLL+I+NGVFEV AT+GDTHLGGEDFD +++   IK +KKK G D++D+ +A+ KL+RE EKAKRALS+  S RIEI+S  DG D SETLTRA+FEELN+DLF+ T+KPVEKVLQD+ ++K+D+++IVLVGGSTRIPKVQQL++ +F+GK+ S+GINPDEAVA+GAAVQAGV+ G E   DIVLLDV  LTLGIET GGVMT LI RNT IPTKKSQ+FSTA DNQPTV I+VYEGER M+KDN+ LGKF+LTGIP APRGVPQIEVTF +D NGILKVSA DKGTG    I I  D+ RL  E+I++M+++AE +A +D  +K KVE++N LE YA+SLK QVN    LG KL   DKET++ A ++ + WL+ N + A  E+F  + + +  +  PI +KLY
Sbjct:   49 YGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVAFT-DDERLIGDAAKNQVAANPQNTIFDIKRLIGLKYNDRSVQKDIKHLPFNVVNKDGKPAVEVSVKGEKKVFTPEEISGMILGKMKQIAEDYLGTKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRIVNEPTAAAIAYGLDKSDKEHQIIVYDLGGGTFDVSLLSIENGVFEVQATSGDTHLGGEDFDYKIVRQLIKAFKKKHGIDVSDNNKALAKLKREAEKAKRALSSQMSTRIEIDSFVDGIDLSETLTRAKFEELNLDLFKKTLKPVEKVLQDSGLEKKDVDDIVLVGGSTRIPKVQQLLESYFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQPTVMIKVYEGERAMSKDNNLLGKFELTGIPPAPRGVPQIEVTFALDANGILKVSATDKGTGKSESITITNDKGRLTQEEIDRMVEEAEKFASEDASIKAKVESRNKLENYAHSLKNQVNG--DLGEKLEEEDKETLLDAANDVLEWLDDNFETAIAEDFDEKFESLSKVAYPITSKLY 654

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA1 (ATPase involved in protein folding and NLS-directed nuclear transport; member of HSP70 family; required for ubiquitin-dependent degradation of short-lived proteins; forms chaperone complex with Ydj1p; localized to nucleus, cytoplasm, cell wall; 98% identical to paralog Ssa2p with different functional specificity in propagation of yeast [URE3] prions, vacuolar-mediated degradations of gluconeogenesis enzymes; general targeting factor of Hsp104p to prion fibrils [Source:SGD;Acc:S000000004])

HSP 1 Score: 760.37 bits (1962), Expect = 0.000e+0
Identity = 392/608 (64.47%), Postives = 491/608 (80.76%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXE--ETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
             +GIDLGTTYSCV  F   RV+IIANDQGNR TPS+VAFT + ERLIGDAAKNQ   NP NTVFD KR+IGRNFND  VQ DMKHFPFK+I+ + KP ++V+   E K+F PE+IS+MVLGKMK  AE+YLG KV  AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKKG E+++L+FDLGGGTFDVSLL+I++G+FEV AT GDTHLGGEDFD R++++FI+ +K+K  KD++ ++RA+++LR   E+AKR LS++    +EI+SL++G DF  ++TRARFEEL  DLFRST+ PVEKVL+DA++ K  ++EIVLVGGSTRIPKVQ+LV ++FNGKEP+R INPDEAVA+GAAVQA ++ G E  +T D++LLDV PL+LGIET GGVMTKLIPRN+ IPTKKS++FST ADNQP V IQV+EGER  TKDN+ LGKF+L+GIP APRGVPQIEVTF++D NGIL VSA +KGTG  NKI I  D+ RL+ EDIEKM+ +AE + ++D+K  +++ +KN LE  AYSLK  +++    G KL  +DK+T+ K  +E ISWL+ N  A  EEF  + K+++DI  PIM+KLYQ
Sbjct:    4 AVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFT-DTERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEA---GDKLEQADKDTVTKKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQ 607

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA2 (HSP70 family ATP-binding protein; involved in protein folding, vacuolar import of proteins; required for ubiquitin-dependent degradation of short-lived proteins; associated with chaperonin-containing T-complex; 98% identical to paralog Ssa1p with distinct functional specificity in propagation of yeast [URE3] prions and vacuolar-mediated degradation of gluconeogenesis enzymes; binds tRNA, has role in tRNA nuclear import during starvation [Source:SGD;Acc:S000003947])

HSP 1 Score: 756.133 bits (1951), Expect = 0.000e+0
Identity = 390/611 (63.83%), Postives = 490/611 (80.20%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXE--ETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
             +GIDLGTTYSCV  F   RV+IIANDQGNR TPS+V FT + ERLIGDAAKNQ   NP NTVFD KR+IGRNFND  VQ DMKHFPFK+I+ + KP ++V+   E K+F PE+IS+MVLGKMK  AE+YLG KV  AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKKG E+++L+FDLGGGTFDVSLL+I++G+FEV AT GDTHLGGEDFD R++++FI+ +K+K  KD++ ++RA+++LR   E+AKR LS++    +EI+SL++G DF  ++TRARFEEL  DLFRST+ PVEKVL+DA++ K  ++EIVLVGGSTRIPKVQ+LV ++FNGKEP+R INPDEAVA+GAAVQA ++ G E  +T D++LLDV PL+LGIET GGVMTKLIPRN+ IPTKKS+VFST ADNQP V IQV+EGER  TKDN+ LGKF+L+GIP APRGVPQIEVTF++D NGIL VSA +KGTG  NKI I  D+ RL+ EDIEKM+ +AE + ++D+K  +++ +KN LE  AYSLK  +++    G KL  +DK+ + K  +E I+WL+ N  A  EEF  Q K+++++  PIM+KLYQ  G
Sbjct:    4 AVGIDLGTTYSCVAHFSNDRVDIIANDQGNRTTPSFVGFT-DTERLIGDAAKNQAAMNPANTVFDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLDVAPLSLGIETAGGVMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERAKTKDNNLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLSKEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEA---GDKLEQADKDAVTKKAEETIAWLDSNTTATKEEFDDQLKELQEVANPIMSKLYQAGG 610

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA3 (ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm; SSA3 has a paralog, SSA4, that arose from the whole genome duplication [Source:SGD;Acc:S000000171])

HSP 1 Score: 748.814 bits (1932), Expect = 0.000e+0
Identity = 389/611 (63.67%), Postives = 481/611 (78.72%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG-GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXE--ETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVND---KEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
             +GIDLGTTYSCV  F   RVEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ   NP NTVFD KR+IGR F+D  V  D KHFPFKVI+++ KP V+V+   E K+F PEEIS+MVL KMK  AE YLG  V  AVVTVPAYFND+QRQAT DAG IAG+NVLRIINEPTAAAIAYGLDKKG  E N+L+FDLGGGTFDVSLL+ID GVFEV AT GDTHLGGEDFD R++++    +K+K  KDI++++R++++LR   E+AKRALS++    IEI+SL++G DF  +LTRARFEEL  DLFRST++PVEKVL+D+++ K  I+EIVLVGGSTRIPK+Q+LV +FFNGKEP+R INPDEAVA+GAAVQA ++ G +  +T D++LLDV PL+LGIET GG+MTKLIPRN+ IPTKKS+ FST ADNQP V IQV+EGER  TKDN+ LGKF+L+GIP APRGVPQI+VTF+ID NGIL VSA +KGTG  NKI I  D+ RL+ +DI++M+ +AE Y   D++  E+V+AKN LE YA++LK  +N+   KEK+G      D + +  A  E I WL+ +Q A T+E+K ++K++E I  PIMTK Y
Sbjct:    4 AVGIDLGTTYSCVAHFSNDRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQAAINPHNTVFDAKRLIGRKFDDPEVTTDAKHFPFKVISRDGKPVVQVEYKGETKTFTPEEISSMVLSKMKETAENYLGTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAAAIAYGLDKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLATEFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCADLFRSTLEPVEKVLKDSKLDKSQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSTKTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDIDANGILNVSALEKGTGKSNKITITNDKGRLSKDDIDRMVSEAEKYRADDEREAERVQAKNQLESYAFTLKNTINEASFKEKVGE----DDAKRLETASQETIDWLDASQAASTDEYKDRQKELEGIANPIMTKFY 609

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Match: SSA4 (Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation; SSA4 has a paralog, SSA3, that arose from the whole genome duplication [Source:SGD;Acc:S000000905])

HSP 1 Score: 743.806 bits (1919), Expect = 0.000e+0
Identity = 388/611 (63.50%), Postives = 481/611 (78.72%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG-GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEE--TGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQV---NDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
             +GIDLGTTYSCV  F   RVEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ   NP NTVFD KR+IGR F+D  V +D KH+PFKVI+K  KP V+V+   E K+F PEEIS+M+L KMK  AE +LG +V  AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK   E N+L+FDLGGGTFDVSLL+ID GVFEV AT GDTHLGGEDFD R++++  + +K+K  KD+T ++R++++LR   E+AKR LS++    IEI+SL++G DF  ++TRARFEEL  DLFRST++PVEKVL D+++ K  I+EIVLVGGSTRIPKVQ+LV +FFNGKEP+R INPDEAVA+GAAVQA ++ G +   T D++LLDV PL+LGIET GG+MTKLIPRN+ IPTKKS+VFST ADNQP V IQV+EGER  TKDN+ LGKF+L+GIP APRGVPQIEVTF+ID NGIL VSA +KGTG  NKI I  D+ RL+ EDI+KM+ +AE +  +D++  ++V+AKN LE YA++LK  V   N KEK+G +    D   +  A  +AI+WL+ +Q A TEE+K ++K++E +  PIM+K Y
Sbjct:    4 AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQAAMNPHNTVFDAKRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFLGTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKSQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLLDVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEKFKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEE----DARKLEAAAQDAINWLDASQAASTEEYKERQKELEGVANPIMSKFY 609

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO33296 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL5])

HSP 1 Score: 955.281 bits (2468), Expect = 0.000e+0
Identity = 501/639 (78.40%), Postives = 563/639 (88.11%), Query Frame = 1

Query:  142 MKSITIIFISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLY 2058
            MK I  I    L  S+  AD  ++ K ++E  GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT EGERLIGD AKNQLTTNPENTVFD KR+IGR+++D +VQ+D+K FPFKV++KN KP V+V+V +E+K+FA EEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGL V+RIINEPTAAAIAYG+DKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQ VM +FIKLYKKKKGK+I  D RAVQKLRREVEKAKRALS  H AR+EIES ++GEDFSE LTRARFEELN  LF+ST+KPV+KVL+DA++KK +I+EIVLVGGSTRIPKVQQLVK+FF GKEPSRGINPDEAVA+GAAVQAGV+GG E+TG++VLLDV PLTLGIETVGGVMTKLI RNTVIPTKKSQVFSTAADNQ TVTIQV+EGERPMTKDNH LGKFDL GIP APRGVPQIEVTFEIDVNGIL+VSAEDKGTGNK KI I  DQNRL  EDIE+M+ DAE +AD+DKK KEKVEA+N+LE YAYSLK QV DKEKLG KLS  DK+TI +AV++AISW++KNQ A  E+FK +KK++ED+V PI++KLY
Sbjct:    1 MKCIYTICTLALASSLVFADKKEERKEQREKVGTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTEEGERLIGDGAKNQLTTNPENTVFDAKRLIGRSWDDTSVQNDLKFFPFKVVDKNKKPHVQVKVKDEIKTFAAEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLTVMRIINEPTAAAIAYGMDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQNVMEHFIKLYKKKKGKNIRKDNRAVQKLRREVEKAKRALSTQHQARVEIESFFEGEDFSEMLTRARFEELNAKLFKSTLKPVQKVLEDADLKKSEIHEIVLVGGSTRIPKVQQLVKDFFEGKEPSRGINPDEAVAYGAAVQAGVLGGEEDTGEVVLLDVNPLTLGIETVGGVMTKLISRNTVIPTKKSQVFSTAADNQNTVTIQVFEGERPMTKDNHPLGKFDLNGIPPAPRGVPQIEVTFEIDVNGILRVSAEDKGTGNKEKITITNDQNRLTPEDIERMVNDAEKFADEDKKTKEKVEARNELESYAYSLKNQVGDKEKLGGKLSEDDKKTITEAVEKAISWMDKNQDASVEDFKKEKKELEDVVQPIVSKLY 639

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO30323 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T144])

HSP 1 Score: 743.036 bits (1917), Expect = 0.000e+0
Identity = 374/610 (61.31%), Postives = 480/610 (78.69%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMK-KEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
             IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT E ERL+GDAAKNQ+  NP NT+FD KR+IGR F+D  V+DDMKH+ F+V+N+  +P V+V+   E K+F  EEIS+MVL KMK  AEAYLG KVT AVVTVPAYFND+QRQAT DAG+I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+L+I++G+FEV +T+GDTHLGGEDFD  ++ +F+K +K+K  KDIT +KRA+++LR   E+AKR LS++  A IEI+SLYDG DF  ++TRARFEE+N  LF+ T++PVEK ++D++++ KE I+EIV+VGGSTRIPK+Q L++ FFNGKE ++ INPDEAVA               E T D++LLDV PLTLG+ET GGVMT  I RNT IPTK++Q F+T +DNQ +V IQVYEGER +TKDN+ LGKF+L+GIP APRGVPQI+VTF++D NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+K+AE +   D+ V+E++++KN LE YA+S+K+ + D EK+  KLS  ++E ++      + WLE NQ AE EE    +K++E +  PI+TKLYQ
Sbjct:    6 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDE-ERLVGDAAKNQVAMNPTNTIFDAKRLIGRRFDDPGVKDDMKHWSFEVVNEAGRPKVKVEYKGETKTFFAEEISSMVLNKMKETAEAYLGCKVTDAVVTVPAYFNDSQRQATKDAGVISGLNVLRIINEPTAAAIAYGLDKKVGQERNVLIFDLGGGTFDVSVLSIEDGIFEVKSTHGDTHLGGEDFDNNMVDFFVKQFKQKYKKDITPNKRALRRLRTACERAKRTLSSSTQASIEIDSLYDGIDFYTSITRARFEEMNAHLFKKTLEPVEKAIKDSKLESKEKIDEIVMVGGSTRIPKIQSLLQNFFNGKELNKSINPDEAVAYGAAVQAAILHGDKSEATQDLLLLDVAPLTLGLETAGGVMTAAIKRNTTIPTKQTQTFTTYSDNQTSVLIQVYEGERSLTKDNNLLGKFELSGIPPAPRGVPQIDVTFDVDSNGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVKEAEKFKAADEAVRERIQSKNSLESYAFSMKSTMED-EKVKDKLSEDEREKVISRCKATLDWLEHNQSAEKEEIDAHQKELEGVCNPIITKLYQ 613

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO37280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG65])

HSP 1 Score: 733.021 bits (1891), Expect = 0.000e+0
Identity = 378/611 (61.87%), Postives = 488/611 (79.87%), Query Frame = 1

Query:  247 IGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGG-EKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMK--KEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEE--TGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQ 2064
            +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAF ++ ERLIGDAAKNQ+  NPENTVFD KR+IGR F+D  V  DM H+PF VI +  +P ++V+   E KSF PEEIS+MVL KMK  AEAYLG KVT AVVTVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK G E+N+L++DLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD +++ +F+K +K+K  KDIT +KRA+++LR   E+AKR LS++  A IEI+SL++G DF  ++TRARFEELN DLF+ T +PVE+ ++D+++   KE I++IVLVGGSTRIPK+Q++++E F GKE ++ INPDEAVA+GAAVQA ++ G ++    D++LLDV PL++GIET GGVM+ LI RN+ IPTK++Q F+T +DNQP V IQV+EGER MT  N+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+ +A  Y ++D+K +++++ KN LE YAYS+K+ V D +K+  K+S  DK+ I+    E + WL+ NQ AE +EF+  +K++E +  PI+TKLYQQ
Sbjct:    7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAF-SDTERLIGDAAKNQVAMNPENTVFDAKRLIGRKFDDPVVARDMTHWPFHVIREGERPKIQVEFKGEKKSFFPEEISSMVLTKMKETAEAYLGAKVTDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGVERNVLIYDLGGGTFDVSVLTIEDGIFEVKSTAGDTHLGGEDFDNKMVDHFVKQFKQKYKKDITPNKRAMRRLRTACERAKRTLSSSTQASIEIDSLFEGIDFYTSITRARFEELNQDLFKKTTEPVEQAIRDSKIPGGKESIHDIVLVGGSTRIPKIQKMLQELFGGKELNKSINPDEAVAYGAAVQAAILHGDKDDTVKDLLLLDVAPLSMGIETAGGVMSVLIKRNSTIPTKQTQTFTTYSDNQPGVLIQVFEGERSMTAHNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVNEASKYKEEDEKQRDRIQTKNSLESYAYSMKSTVED-DKVKDKISEEDKKAILDKCTEVLKWLDTNQTAEKDEFEYHQKELEKVCNPIITKLYQQ 615

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO44530 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RV88])

HSP 1 Score: 727.243 bits (1876), Expect = 0.000e+0
Identity = 374/613 (61.01%), Postives = 485/613 (79.12%), Query Frame = 1

Query:  244 VIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNG-VFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXX--XXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
             IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYV FT + ERL+GDAAKNQ+  NPENT+FD KR+IGR ++D TVQ DMK +PFK+I+ NNKP ++V+   E K+FA EEIS+MVLGKMK  AEAYLG+KVT AV+TVPAYFND+QRQAT DAG IAGLNVLR+INEPTAAA+AYGLDK   GEKN+L+FDLGGGTFDVS+LTID+G +FEV +T GDTHLGGEDFD R++++F+  +K+K  KD++ + RA+++LR   E+AKR LS++  A IE++SL++G DF   ++RARFE+L  DLF S + PV K L DA+  K DI+E+VLVGGSTR+PK+Q++++E+F+GK  ++ INPDEAVA+GAAVQA        +E  D++L+DV PL+LGIET G VMTKLI RN  IPTK +Q F+T +DNQP VTI+V+EGERP+TK N+ LGKFDL+GIP APRGVPQIEVTF+ID NGIL VSA+DK TG    I I  D+ RL+ E+I++MI DAE Y  +D+  +EK+ A+N LE YA+ +K+ +++   L  KLS SDK+T+   V+E ++WLEKN  AE EEF+ Q+K+++ + +PIM K++  SG
Sbjct:    6 AIGIDLGTTYSCVGVFQNGKVEIIANDQGNRTTPSYVGFT-DTERLVGDAAKNQVALNPENTIFDAKRLIGRRYDDATVQSDMKLWPFKIISDNNKPKIQVEYKGERKTFAAEEISSMVLGKMKETAEAYLGQKVTSAVITVPAYFNDSQRQATKDAGTIAGLNVLRVINEPTAAALAYGLDKSLSGEKNVLIFDLGGGTFDVSILTIDDGSLFEVKSTAGDTHLGGEDFDNRLVNHFVAEFKRKYKKDMSKNSRAMRRLRTACERAKRTLSSSTEASIEVDSLFEGIDFYTKISRARFEDLCSDLFLSCLDPVNKALSDAKFSKSDIHEVVLVGGSTRVPKIQKMLEEYFSGKSLNKSINPDEAVAYGAAVQAAILSGDKSDEVKDVLLVDVAPLSLGIETAGEVMTKLIERNARIPTKATQTFTTYSDNQPAVTIRVFEGERPLTKHNNLLGKFDLSGIPPAPRGVPQIEVTFDIDANGILNVSAKDKSTGKTGSITITNDKGRLSKEEIDRMINDAEKYKSEDEAQREKIAARNRLESYAFGVKSAISEPS-LEGKLSQSDKDTVKNKVEEVLNWLEKNSLAEKEEFEEQEKELQRVCSPIMAKVHGGSG 616

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Match: EDO47723 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN7])

HSP 1 Score: 536.569 bits (1381), Expect = 0.000e+0
Identity = 309/575 (53.74%), Postives = 402/575 (69.91%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSE------TLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVND-KEKLGAKLSPSDKETIVK 1941
            G V GIDLGTT SCV V  G   ++I N +G+R TPS VAFT EGERL+G  A+ Q  TNP+NT++  KR IGR F+   ++ D+K+  +K++  +N  +     G   K ++P ++ A VL KMK  AE+YLG  V +AVVTVPAYFND+QRQAT DAG IAGLNVLR+INEPTAAA+AYG+DK   +K I V+DLGGGTFD+S+L I  GVFEV ATNGDT+LGGEDFD  ++ + I  +KK+ G D++ D  A+Q+LR   EKAK  LS+  S + +I   Y   D S        L+R++FE L  DL   T+ P +K LQDAE+ K +I +++LVGG TR+PKVQQ V++ F G+ PS+ +NPDEAVA GAA+Q GV+ G  +  D++LLDV PL+LGIET+GGV TKLI RNT IPTKKSQVFSTAAD Q  V I+V++GER M  DN  LG+F L GIP APRGVPQ+EVTF+ID NGI+ VSA DKGTG + +I+IQ     L+ + IE MIK+AE YA+ DK+ KE  EA N  EG  +  +T++ + K++L ++     KE I K
Sbjct:   12 GAVCGIDLGTTNSCVAVMDGKTPKVIENAEGSRTTPSVVAFTPEGERLVGAPARRQAITNPQNTLYATKRYIGRRFDAPEIKKDLKNVSYKIVRASNGDAWFEVAG---KVYSPSQVGAFVLMKMKETAESYLGTNVNNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKTE-DKIIAVYDLGGGTFDISILEIQKGVFEVKATNGDTYLGGEDFDNTLLKFLIAEFKKESGVDLSKDSMALQRLREAAEKAKIELSS--SVQTDINLPYITVDASGPKHLNMKLSRSKFESLVADLINRTVGPCKKCLQDAEINKGEIGDVLLVGGMTRMPKVQQTVQDIF-GRVPSKAVNPDEAVAIGAAIQGGVLAG--DVKDVLLLDVTPLSLGIETLGGVFTKLITRNTTIPTKKSQVFSTAADGQTQVEIKVFQGEREMAIDNKLLGQFQLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDKGTGREQQIVIQSSGG-LSKDAIENMIKEAEKYAEADKQKKETTEAVNQAEGMIHDTETKMEEFKDQLPSEEVEKLKEEIAK 576

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa5 (heat shock protein family A (Hsp70) member 5 [Source:NCBI gene;Acc:101157378])

HSP 1 Score: 976.082 bits (2522), Expect = 0.000e+0
Identity = 492/612 (80.39%), Postives = 558/612 (91.18%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLT+NPENTVFD KR+IGR++ D +VQ D+K+FPFKVI K +KP +++ +G  ++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS  H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK +I+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G E+TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  EDIE+M+ DAE +AD+DK++KE+++A+N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I W+E +Q AETE+F+ +KK++E++V PI+TKLY  +G
Sbjct:   26 GTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDVVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKRLKERIDARNELESYAYSLKNQIGDKEKLGGKLSDDDKETIEKAVEEKIEWMESHQDAETEDFQAKKKELEEVVQPIITKLYGSAG 637

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Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGN-EVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            GTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT+EGERLIGDAAKNQLT+NPENTVFD KR+IGR++ D +VQ D+K+FPFKVI K +KP +++ +G  ++K+FAPEEISAMVL KMK  AEAYLGKKVTHAVVTVPAYFNDAQRQAT DAG IAGLNV+RIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM +FIKLYKKK GKD+  D RAVQKLRREVEKAKRALS  H ARIEIES ++GEDFSETLTRA+FEELNMDLFRSTMKPV+KVL+D+++KK +I+EIVLVGGSTRIPK+QQLVKEFFNGKEPSRGINPDEAVA+GAAVQAGV+ G E+TGD+VLLDVCPLTLGIETVGGVMTKLIPRNTV+PTKKSQ+FSTA+DNQPTVTI+VYEGERP+TKDNH LG FDLTGIP APRGVPQIEVTFEIDVNGIL+V+AEDKGTGNKNKI I  DQNRL  EDIE+M+ DAE +AD+DK++KE+++A+N+LE YAYSLK Q+ DKEKLG KLS  DKETI KAV+E I W+E +Q AETE+F+ +KK++E++V PI+TKLY  +G
Sbjct:   26 GTVIGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTSEGERLIGDAAKNQLTSNPENTVFDAKRLIGRSWGDSSVQQDIKYFPFKVIEKKSKPHIQIDIGGGQMKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKKDGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSEIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEEDTGDVVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNDAERFADEDKRLKERIDARNELESYAYSLKNQIGDKEKLGGKLSDDDKETIEKAVEEKIEWMESHQDAETEDFQAKKKELEEVVQPIITKLYGSAG 637

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hspa8b (heat shock cognate 70 kDa protein [Source:NCBI gene;Acc:100125490])

HSP 1 Score: 785.023 bits (2026), Expect = 0.000e+0
Identity = 399/611 (65.30%), Postives = 489/611 (80.03%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N +P V+V+   E K+F PEEIS+MVL KMK IAEAYLGK VT+AVVTVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T ADNQP V IQV+EGER MTKDN+ LGKFDLTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   +EKV AKN LE YA+++K+ V ++EKL  K+S  D++ I+   +E ISWL++NQ AE EEF+ Q+K++E +  PIMTKLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPNNTVFDAKRLIGRRFDDSVVQSDMKHWPFTVINDNTRPKVKVEYKGETKTFYPEEISSMVLVKMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFISEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKALRDAKMDKAQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYADNQPGVLIQVFEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQREKVSAKNGLESYAFNMKSTV-EEEKLKDKISEDDRKKILDKCNEVISWLDRNQSAEKEEFEHQQKELEKVCNPIMTKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsp70-3 (heat shock protein 70 [Source:NCBI gene;Acc:100125493])

HSP 1 Score: 783.867 bits (2023), Expect = 0.000e+0
Identity = 391/611 (63.99%), Postives = 494/611 (80.85%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  +GIDLGTTYSCVG+F+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PFKV+N ++KP VEV+   E+K+F PEEIS+MVL KMK I+EAYLGK VT+AV+TVPAYFND+QRQAT DAG IAGLNVLRIINEPTAAAIAYGLDKK GGE+N+L+FDLGGGTFDVS+LTI++G+FEV AT GDTHLGGEDFD R++++FI  +K+K  K+IT++KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T++PVEK L+DA+M K  I+++VLVGGSTRIPK+Q+L+++ FNG++ ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGIL VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE +  +D+  ++K+ AKN LE  A+++K+ V+D EKL  K+S  DK+TIV   +E I+WL+KNQ AE +E++ Q+K++E +  PI++KLYQ
Sbjct:    4 GPAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPANTVFDAKRLIGRKFDDAVVQSDMKHWPFKVVNDSSKPKVEVEYKGEIKTFYPEEISSMVLTKMKEISEAYLGKSVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFDLGGGTFDVSILTIEDGIFEVKATAGDTHLGGEDFDNRMVNHFITEFKRKFKKEITNNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGTDFYTSITRARFEELNADLFRGTIEPVEKALRDAKMDKSQIHDVVLVGGSTRIPKIQKLLQDLFNGRDLNKSINPDEAVAYGAAVQAAILAGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGKFELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEQFKAEDESQRDKITAKNSLESLAFNMKSTVDD-EKLQDKISSEDKKTIVDKCNEIIAWLDKNQMAEKDEYEHQQKELEKVCNPIISKLYQ 612

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BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Match: hsc70 (heat shock protein 70 cognate [Source:NCBI gene;Acc:100049425])

HSP 1 Score: 781.941 bits (2018), Expect = 0.000e+0
Identity = 396/610 (64.92%), Postives = 487/610 (79.84%), Query Frame = 1

Query:  247 IGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQS 2067
            IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F+D  VQ DMKH+PF VIN N +P V+V+   E KSF PEEIS+MVL KMK IAEAYLGK V +AV+TVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI  +K+K  KDI+D+KRAV++LR   E+AKR LS++  A IEI+SLY+G DF  ++TRARFEELN DLFR T+ PVEK L+DA+M K  I++IVLVGGSTRIPK+Q+L+++FFNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q F+T +DNQP V IQVYEGER MTKDN+ LGKF+LTGIP APRGVPQIEVTF+ID NGI+ VSA DK TG +NKI I  D+ RL+ EDIE+M+++AE Y  +D   ++KV AKN LE YA+++K+ V D EKL  K+S  DK+ I+   +E ISWL+KNQ AE +E++ Q+K++E +  PI+TKLYQ +
Sbjct:    4 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPTNTVFDAKRLIGRRFDDHVVQSDMKHWPFNVINDNTRPKVQVEYKGETKSFYPEEISSMVLTKMKEIAEAYLGKTVNNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIAEFKRKYKKDISDNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKMDKGQIHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAEDDVQRDKVSAKNGLESYAFNMKSTVED-EKLAGKISDEDKQKILDKCNEVISWLDKNQTAERDEYEHQQKELEKVCNPIITKLYQSA 611

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BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000062699.1 (SMESG000062699.1)

HSP 1 Score: 1180.62 bits (3053), Expect = 0.000e+0
Identity = 643/643 (100.00%), Postives = 643/643 (100.00%), Query Frame = 1

Query:  142 MKSITIIFISLLICSIYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            MKSITIIFISLLICSIYAADDDKKEKTKKEDYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIKLYKKKKGKDITDDKRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG
Sbjct:    1 MKSITIIFISLLICSIYAADDDKKEKTKKEDYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIKLYKKKKGKDITDDKRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAFGAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 643

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1)

HSP 1 Score: 996.112 bits (2574), Expect = 0.000e+0
Identity = 527/640 (82.34%), Postives = 583/640 (91.09%), Query Frame = 1

Query:  163 FISLLICS----IYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            FI +++C      YA ++ K  ++ K+DYGTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENT+FDVKR IGR F+D+TV+ D+K++PF VINKNNKP V+V+VG E + FAPEEISAMVLGKMK IAE+YLGK+VTHAVVTVPAYFNDAQRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLY+KK GKD+  D RAVQKLRREVEKAKR+LSN+HSARI+IES YDG+DFSETLTRARFEELNMDLF++TMKPVEKVLQD+++KKED++EIVLVGGSTRIPK+QQLVKE F+GKEPSRGINPDEAVAFGAAVQAGVIGG EETGD+VLLDVCPLTLGIETVG VMTKLIPRNTVIPTKKSQ+FSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKI+I KDQNRL+ E+IEKMI DAE +A+ DKK+K+KVEAKN+LEGYAYSLKTQVNDK KLG KLS  +++ I+ A  E ISWLEKN QAE EEFK +KKK+EDI  PI++K YQQ G
Sbjct:    6 FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYFIKLYRKKHGKDVRKDNRAVQKLRREVEKAKRSLSNSHSARIDIESFYDGDDFSETLTRARFEELNMDLFKNTMKPVEKVLQDSDLKKEDVSEIVLVGGSTRIPKIQQLVKELFDGKEPSRGINPDEAVAFGAAVQAGVIGGAEETGDLVLLDVCPLTLGIETVGAVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIVINKDQNRLSPENIEKMINDAEKFAESDKKLKDKVEAKNELEGYAYSLKTQVNDKTKLGGKLSADEQKIILDAAQETISWLEKNPQAEVEEFKKEKKKLEDIAQPIVSKFYQQEG 645

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000068215.1 (SMESG000068215.1)

HSP 1 Score: 995.727 bits (2573), Expect = 0.000e+0
Identity = 527/640 (82.34%), Postives = 583/640 (91.09%), Query Frame = 1

Query:  163 FISLLICS----IYAAXXXXXXXXXXXXYGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            FI +++C      YA ++ K  ++ K+DYGTVIGIDLGTTYSCVGVFK GRVEIIANDQGNRITPSYVAFT E ERLIGDAAKNQLT+NPENT+FDVKR IGR F+D+TV+ D+K++PF VINKNNKP V+V+VG E + FAPEEISAMVLGKMK IAE+YLGK+VTHAVVTVPAYFNDAQRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK GEKNILVFDLGGGTFDVSLLTIDNGVFEV+ATNGDTHLGGEDFDQRVM YFIKLY+KK GKD+  D RAVQKLRREVEKAKR+LSN+HSARI+IES YDG+DFSETLTRARFEELNMDLF++TMKPVEKVLQD+++KKED++EIVLVGGSTRIPK+QQLVKE F+GKEPSRGINPDEAVAFGAAVQAGVIGG EETGD+VLLDVCPLTLGIETVG VMTKLIPRNTVIPTKKSQ+FSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKI+I KDQNRL+ E+IEKMI DAE +A+ DKK+K+KVEAKN+LEGYAYSLKTQVNDK KLG KLS  +++ I+ A  E ISWLEKN QAE EEFK +KKK+EDI  PI++K YQQ G
Sbjct:    7 FICIILCINVVISYATENKKDSESPKDDYGTVIGIDLGTTYSCVGVFKSGRVEIIANDQGNRITPSYVAFTQESERLIGDAAKNQLTSNPENTIFDVKRFIGRGFDDETVKQDIKNYPFLVINKNNKPHVQVKVGEENRIFAPEEISAMVLGKMKEIAESYLGKRVTHAVVTVPAYFNDAQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKEGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMDYFIKLYRKKHGKDVRKDNRAVQKLRREVEKAKRSLSNSHSARIDIESFYDGDDFSETLTRARFEELNMDLFKNTMKPVEKVLQDSDLKKEDVSEIVLVGGSTRIPKIQQLVKELFDGKEPSRGINPDEAVAFGAAVQAGVIGGAEETGDLVLLDVCPLTLGIETVGAVMTKLIPRNTVIPTKKSQIFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIVINKDQNRLSPENIEKMINDAEKFAESDKKLKDKVEAKNELEGYAYSLKTQVNDKTKLGGKLSADEQKIILDAAQETISWLEKNPQAEVEEFKKEKKKLEDIAQPIVSKFYQQEG 646

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000061528.1 (SMESG000061528.1)

HSP 1 Score: 860.136 bits (2221), Expect = 0.000e+0
Identity = 448/616 (72.73%), Postives = 513/616 (83.28%), Query Frame = 1

Query:  235 YGTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKKG----GEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXXXXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSG 2070
            YGTVIGIDLGTTYSCVG+FK GRVEII NDQGNRITPSY+AFT +GERLIGD+AKNQLTTNP NT+FDVKR+IGR + D +VQ D+ H+PFKVIN +NKP + V +  E KSF PEEISAMVLGKMK IAE YLGKKVTHAVVTVPAYFNDAQRQAT +AGIIAGL VLRIINEPTAAAIAYGLDKK      E  ILVFDLGGGTFDVSLLTID GVFEV+ATNGDTHLGGEDFDQRV+ YF  LYKKKK KD+  D RA+QKLRREVEKAKRALS+  + RIEIESL DGEDFSETLTRA+FEELN DLF+ST+ PVEKVLQDA +KK DI EIVLVGGSTRIPKVQ+LV+ FFNGKEP++GINPDEAVA+GAAVQAGV+ G   TGD++LLDVCPLTLG+E  GGVM KLI RNT IPT K  VF+T  DNQ TVT  VYEGER + KDNHFLG+FDLTGIP APRGVPQIEVTFEID NGILKVSAEDKGTGNK  I+I  D+NRL  EDI+KMIKDAE + ++D+ +K+++EA+++LE Y YS+K Q+NDK KLG K+S  D +    AV + I WL+ N+ A  E++  QK  +E I+ PI++KLY++ G
Sbjct:   34 YGTVIGIDLGTTYSCVGIFKEGRVEIIPNDQGNRITPSYIAFTQDGERLIGDSAKNQLTTNPVNTIFDVKRLIGREWTDSSVQKDITHYPFKVINVDNKPHISVNIKGEEKSFQPEEISAMVLGKMKTIAEEYLGKKVTHAVVTVPAYFNDAQRQATKNAGIIAGLIVLRIINEPTAAAIAYGLDKKAKSEPKEHQILVFDLGGGTFDVSLLTIDQGVFEVVATNGDTHLGGEDFDQRVIDYFSLLYKKKKNKDLKKDIRAIQKLRREVEKAKRALSSVLTTRIEIESLIDGEDFSETLTRAKFEELNADLFKSTLIPVEKVLQDANLKKNDIAEIVLVGGSTRIPKVQELVRGFFNGKEPNKGINPDEAVAYGAAVQAGVLSGDSTTGDLLLLDVCPLTLGMELEGGVMAKLINRNTPIPTIKKDVFTTVVDNQNTVTTAVYEGERQLVKDNHFLGQFDLTGIPPAPRGVPQIEVTFEIDANGILKVSAEDKGTGNKQHIVITNDKNRLKPEDIDKMIKDAEKFKEEDESIKQRIEARSELEQYVYSMKNQLNDKTKLGGKISSDDLKKSNDAVLKVIDWLDLNKSATKEDYIKQKSDIESILNPIVSKLYEKDG 649

[Close]

BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Match: SMESG000051570.1 (SMESG000051570.1)

HSP 1 Score: 774.237 bits (1998), Expect = 0.000e+0
Identity = 391/611 (63.99%), Postives = 486/611 (79.54%), Query Frame = 1

Query:  238 GTVIGIDLGTTYSCVGVFKGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDVKRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEISAMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVLRIINEPTAAAIAYGLDKK-GGEKNILVFDLGGGTFDVSLLTIDNGVFEVIATNGDTHLGGEDFDQRVMHYFIXXXXXXXXXXXXXXXRAVQKLRREVEKAKRALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVLQDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEXXX--XXXXXXXXXXXXXEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQIEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAETYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVKAVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQ 2061
            G  IGIDLGTTYSCVGVF+ G+VEIIANDQGNR TPSYVAFT + ERLIGDAAKNQ+  NP NTVFD KR+IGR F++ +VQ DMKH+ F VIN+  +P + V+   E K+F PEEIS+MVL KMK IAEAYLGK V  AVVTVPAYFND+QRQAT DAG I+GLNVLRIINEPTAAAIAYGLDKK G E+N+L+FDLGGGTFDVS+LTI++G+FEV +T GDTHLGGEDFD R++++FI+ +K+K  KDI+D+KRAV++LR   E+AKR LS++  A +EI+SLY+G DF  ++TRARFEELN DLFRST++PVEK L+DA++ K  I++IVLVGGSTRIPK+Q+L+++ FNGKE ++ INPDEAVA               E   D++LLDV PL+LGIET GGVMT LI RNT IPTK++Q+F+T +DNQP V IQVYEGER MTKDN+ LGKF+L GIP APRGVPQIEVTF+ID NGIL VSA +KGTG +NKI I  D+ RL+ +DIE+M+ +AE Y  +D++ K+++  KN LE YAY +K+ V D EKL  K+S SD++ I+    EAI+WLEKNQQA  EEF+   K++E +  PIMTK+YQ
Sbjct:    3 GNAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFDESSVQSDMKHWSFDVINETGRPKIRVEFKGETKTFFPEEISSMVLIKMKEIAEAYLGKTVKDAVVTVPAYFNDSQRQATKDAGAISGLNVLRIINEPTAAAIAYGLDKKVGAERNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNHFIQEFKRKHKKDISDNKRAVRRLRTACERAKRTLSSSAQANLEIDSLYEGIDFYTSITRARFEELNADLFRSTLEPVEKALRDAKLDKNTIHDIVLVGGSTRIPKIQKLLQDLFNGKELNKSINPDEAVAYGAAVQAAILSGDKSEAVQDLLLLDVAPLSLGIETAGGVMTALIKRNTTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELAGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKENKITITNDKGRLSKDDIERMVNEAEKYKKEDEEQKDRIAGKNSLESYAYQMKSTVED-EKLKDKISESDRKLIIDKCQEAINWLEKNQQATKEEFEYHYKELEKLCNPIMTKMYQ 611

The following BLAST results are available for this feature:

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
HSPA5	0.000e+0	79.74	heat shock protein family A (Hsp70) member 5 [Sour...	[more]
HSPA8	0.000e+0	64.65	heat shock protein family A (Hsp70) member 8 [Sour...	[more]
HSPA8	0.000e+0	64.65	heat shock protein family A (Hsp70) member 8 [Sour...	[more]
HSPA8	0.000e+0	64.65	heat shock protein family A (Hsp70) member 8 [Sour...	[more]
HSPA2	0.000e+0	63.78	heat shock protein family A (Hsp70) member 2 [Sour...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hsp-3	0.000e+0	77.21	Heat shock 70 kDa protein C [Source:UniProtKB/Swi...	[more]
hsp-3	0.000e+0	77.21	Heat shock 70 kDa protein C [Source:UniProtKB/Swi...	[more]
hsp-3	0.000e+0	77.21	Heat shock 70 kDa protein C [Source:UniProtKB/Swi...	[more]
hsp-3	0.000e+0	77.21	Heat shock 70 kDa protein C [Source:UniProtKB/Swi...	[more]
hsp-3	0.000e+0	77.21	Heat shock 70 kDa protein C [Source:UniProtKB/Swi...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hsc70-3	0.000e+0	79.21	gene:FBgn0001218 transcript:FBtr0073610	[more]
Hsc70-3	0.000e+0	79.21	gene:FBgn0001218 transcript:FBtr0345166	[more]
Hsc70-3	0.000e+0	79.21	gene:FBgn0001218 transcript:FBtr0073609	[more]
Hsc70-3	0.000e+0	79.21	gene:FBgn0001218 transcript:FBtr0073611	[more]
Hsc70-3	0.000e+0	79.21	gene:FBgn0001218 transcript:FBtr0073608	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hspa5	0.000e+0	80.07	heat shock protein 5 [Source:NCBI gene;Acc:378848]	[more]
hspa8	0.000e+0	64.60	heat shock protein 8 [Source:NCBI gene;Acc:573376]	[more]
hspa8	0.000e+0	64.60	heat shock protein 8 [Source:NCBI gene;Acc:573376]	[more]
hspa8	0.000e+0	64.60	heat shock protein 8 [Source:NCBI gene;Acc:573376]	[more]
hspa8	0.000e+0	64.60	heat shock protein 8 [Source:NCBI gene;Acc:573376]	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
nsg1	0.000e+0	77.48	neuronal vesicle trafficking associated 1 [Source:...	[more]
nsg1	0.000e+0	77.83	neuronal vesicle trafficking associated 1 [Source:...	[more]
nsg1	0.000e+0	77.97	neuronal vesicle trafficking associated 1 [Source:...	[more]
nsg1	0.000e+0	80.03	neuronal vesicle trafficking associated 1 [Source:...	[more]
nsg1	0.000e+0	79.24	neuronal vesicle trafficking associated 1 [Source:...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Hspa5	0.000e+0	79.58	heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95...	[more]
Hspa5	0.000e+0	79.58	heat shock protein 5 [Source:MGI Symbol;Acc:MGI:95...	[more]
Hspa8	0.000e+0	64.81	heat shock protein 8 [Source:MGI Symbol;Acc:MGI:10...	[more]
Hspa2	0.000e+0	63.62	heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96...	[more]
Hspa2	0.000e+0	63.62	heat shock protein 2 [Source:MGI Symbol;Acc:MGI:96...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q16956\|BIP_APLCA	0.000e+0	82.32	Endoplasmic reticulum chaperone BiP OS=Aplysia cal...	[more]
sp\|Q90593\|BIP_CHICK	0.000e+0	79.90	Endoplasmic reticulum chaperone BiP OS=Gallus gall...	[more]
sp\|Q0VCX2\|BIP_BOVIN	0.000e+0	79.90	Endoplasmic reticulum chaperone BiP OS=Bos taurus ...	[more]
sp\|Q91883\|BIP_XENLA	0.000e+0	80.03	Endoplasmic reticulum chaperone BiP OS=Xenopus lae...	[more]
sp\|P06761\|BIP_RAT	0.000e+0	79.74	Endoplasmic reticulum chaperone BiP OS=Rattus norv...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
G8JF14	0.000e+0	94.56	Glucose-regulated protein 78 OS=Dugesia japonica O...	[more]
A0A1I8HNI7	0.000e+0	81.23	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8H5I1	0.000e+0	82.53	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A267GFX2	0.000e+0	82.73	Uncharacterized protein (Fragment) OS=Macrostomum ...	[more]
A0A0N5AHC4	0.000e+0	79.78	Uncharacterized protein OS=Syphacia muris OX=45137...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hspa5	0.000e+0	80.59	heat shock protein family A (Hsp70) member 5 [Sour...	[more]
hspa8	0.000e+0	64.44	heat shock cognate 71 kDa protein [Source:NCBI gen...	[more]
hspa8b	0.000e+0	64.81	heat shock cognate 70 kDa protein-like [Source:NCB...	[more]
ENSAMXT00000004733.2	0.000e+0	63.99	pep primary_assembly:Astyanax_mexicanus-2.0:20:275...	[more]
hsc70	0.000e+0	63.99	heat shock cognate 71 kDa protein-like [Source:NCB...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4


Match Name	E-value	Identity	Description
hspa5	0.000e+0	80.92	heat shock protein 5 [Source:NCBI gene;Acc:378848]	[more]
hspa9	0.000e+0	51.47	heat shock protein 9 [Source:ZFIN;Acc:ZDB-GENE-030...	[more]
hspa14	2.702e-73	31.66	heat shock protein 14 [Source:NCBI gene;Acc:565232...	[more]
hspa13	3.359e-72	34.73	heat shock protein 70 family, member 13 [Source:ZF...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
KAR2	0.000e+0	66.83	ATPase involved in protein import into the ER; als...	[more]
SSA1	0.000e+0	64.47	ATPase involved in protein folding and NLS-directe...	[more]
SSA2	0.000e+0	63.83	HSP70 family ATP-binding protein; involved in prot...	[more]
SSA3	0.000e+0	63.67	ATPase involved in protein folding and the respons...	[more]
SSA4	0.000e+0	63.50	Heat shock protein that is highly induced upon str...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO33296	0.000e+0	78.40	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO30323	0.000e+0	61.31	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37280	0.000e+0	61.87	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44530	0.000e+0	61.01	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47723	0.000e+0	53.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
hspa5	0.000e+0	80.39	heat shock protein family A (Hsp70) member 5 [Sour...	[more]
hspa5	0.000e+0	80.39	heat shock protein family A (Hsp70) member 5 [Sour...	[more]
hspa8b	0.000e+0	65.30	heat shock cognate 70 kDa protein [Source:NCBI gen...	[more]
hsp70-3	0.000e+0	63.99	heat shock protein 70 [Source:NCBI gene;Acc:100125...	[more]
hsc70	0.000e+0	64.92	heat shock protein 70 cognate [Source:NCBI gene;Ac...	[more]

BLAST of Endoplasmic reticulum chaperone BiP vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000062699.1	0.000e+0	100.00	SMESG000062699.1	[more]
SMESG000068215.1	0.000e+0	82.34	SMESG000068215.1	[more]
SMESG000068215.1	0.000e+0	82.34	SMESG000068215.1	[more]
SMESG000061528.1	0.000e+0	72.73	SMESG000061528.1	[more]
SMESG000051570.1	0.000e+0	63.99	SMESG000051570.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025067 ID=SMED30025067|Name=Endoplasmic reticulum chaperone BiP|organism=Schmidtea mediterranea sexual|type=transcript|length=2317bp
CTACGACCAATCAAAATTTCACACGAATATTAGAACACACAATAATTCTC
TTATACGTGTATATATTCATATAAAAGGGATTTATTTATATTATTTCTAT
CATTTCTGTATTGTTCTTTAATACGAAACTTATTTGAATCGATGAAATCG
ATAACAATTATCTTTATTTCATTATTGATTTGCAGTATTTATGCTGCAGA
CGATGATAAAAAGGAGAAAACTAAAAAGGAAGATTATGGAACTGTTATTG
GTATAGATTTGGGAACTACTTATTCATGCGTTGGTGTCTTTAAAGGAGGT
CGTGTAGAAATAATTGCAAACGATCAAGGAAACAGAATCACTCCATCATA
TGTGGCTTTCACTGCTGAAGGTGAAAGGTTGATTGGAGACGCAGCAAAGA
ATCAATTAACTACAAATCCTGAAAATACAGTTTTCGATGTCAAAAGAATT
ATTGGCAGAAATTTCAACGATAAAACTGTTCAGGATGACATGAAGCATTT
TCCATTTAAAGTTATAAACAAAAATAATAAACCAAGTGTGGAAGTTCAGG
TAGGAAATGAAGTTAAATCTTTCGCACCAGAAGAAATATCTGCCATGGTT
TTAGGTAAGATGAAAGTTATAGCTGAGGCTTACTTGGGTAAGAAAGTCAC
TCATGCAGTTGTAACTGTACCTGCATATTTTAATGATGCCCAAAGACAAG
CAACAAGTGATGCTGGAATAATTGCTGGATTGAATGTATTGAGAATTATT
AACGAACCTACAGCAGCGGCCATTGCATATGGATTGGACAAAAAAGGAGG
TGAAAAAAACATTCTTGTATTTGACCTTGGAGGAGGAACTTTTGATGTTT
CATTGTTGACAATCGATAATGGAGTTTTTGAAGTTATTGCAACTAATGGA
GATACTCACTTGGGAGGTGAAGATTTCGATCAAAGAGTAATGCATTACTT
CATTAAATTATACAAGAAAAAGAAAGGAAAGGATATCACCGATGACAAAA
GAGCTGTTCAGAAATTGCGTAGAGAAGTTGAAAAGGCCAAGAGAGCATTG
AGTAATGCACACAGTGCAAGAATTGAAATTGAATCATTATACGATGGTGA
AGATTTCTCAGAAACATTGACAAGAGCTAGATTTGAAGAATTAAACATGG
ATTTGTTTAGATCTACGATGAAACCAGTAGAAAAAGTACTACAGGATGCT
GAAATGAAAAAAGAGGATATTAATGAAATTGTTCTTGTCGGTGGTTCAAC
TAGAATTCCTAAAGTTCAACAGTTAGTTAAAGAATTTTTTAATGGCAAAG
AACCCAGTCGAGGTATTAATCCAGATGAAGCTGTTGCTTTTGGTGCAGCT
GTTCAGGCCGGTGTTATTGGTGGTGTTGAAGAAACCGGAGATATCGTTCT
TTTGGATGTATGCCCATTGACTTTAGGTATTGAAACAGTTGGTGGTGTTA
TGACCAAATTAATTCCAAGAAACACTGTTATTCCTACTAAAAAATCACAA
GTCTTTTCAACAGCAGCTGATAATCAACCAACTGTCACAATTCAGGTTTA
TGAAGGAGAGAGACCTATGACTAAGGATAATCATTTCCTTGGTAAATTTG
ATCTTACTGGCATTCCAGCTGCACCTCGTGGTGTTCCACAAATTGAAGTT
ACATTTGAAATAGATGTTAATGGTATTCTGAAAGTATCAGCGGAAGACAA
AGGTACTGGAAACAAGAACAAAATCATCATTCAAAAAGACCAAAATAGAT
TGAATACTGAAGACATTGAAAAAATGATTAAAGATGCTGAAACATATGCT
GACCAGGATAAGAAAGTGAAAGAAAAGGTTGAAGCTAAAAACGACTTAGA
AGGTTATGCTTATTCATTGAAAACTCAGGTAAATGATAAAGAAAAATTGG
GAGCTAAATTAAGCCCTTCAGACAAAGAAACTATAGTAAAAGCAGTTGAT
GAAGCTATTAGTTGGTTAGAGAAGAATCAACAAGCAGAAACTGAAGAATT
TAAAGTGCAAAAGAAGAAAGTTGAAGATATTGTTACACCAATTATGACCA
AGTTATATCAACAAAGTGGTGCACCTCCTCCCCAACCTGATGATAAGAAA
GACGATGCTAAAACTGAATTGTAATACTTTCACTTTCTCAGATCAAGCTT
TTTAATGTATATATTTTCTGTTATTGTTTTCTAATAAATTCCAATTTCCG
GATGTTTAAGTTTTTGAATTTTCAATCTTTTAATTGAAATAATTTGGTTA
GTCAATTTAGTGTTGTTCAAAAGGAAAGGGTTAATTTTTTATAAATAAAG
GTTTGGAAAGCAAAACA

protein sequence of SMED30025067-orf-1

>SMED30025067-orf-1 ID=SMED30025067-orf-1|Name=SMED30025067-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=661bp
MKSITIIFISLLICSIYAADDDKKEKTKKEDYGTVIGIDLGTTYSCVGVF
KGGRVEIIANDQGNRITPSYVAFTAEGERLIGDAAKNQLTTNPENTVFDV
KRIIGRNFNDKTVQDDMKHFPFKVINKNNKPSVEVQVGNEVKSFAPEEIS
AMVLGKMKVIAEAYLGKKVTHAVVTVPAYFNDAQRQATSDAGIIAGLNVL
RIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSLLTIDNGVFEVIA
TNGDTHLGGEDFDQRVMHYFIKLYKKKKGKDITDDKRAVQKLRREVEKAK
RALSNAHSARIEIESLYDGEDFSETLTRARFEELNMDLFRSTMKPVEKVL
QDAEMKKEDINEIVLVGGSTRIPKVQQLVKEFFNGKEPSRGINPDEAVAF
GAAVQAGVIGGVEETGDIVLLDVCPLTLGIETVGGVMTKLIPRNTVIPTK
KSQVFSTAADNQPTVTIQVYEGERPMTKDNHFLGKFDLTGIPAAPRGVPQ
IEVTFEIDVNGILKVSAEDKGTGNKNKIIIQKDQNRLNTEDIEKMIKDAE
TYADQDKKVKEKVEAKNDLEGYAYSLKTQVNDKEKLGAKLSPSDKETIVK
AVDEAISWLEKNQQAETEEFKVQKKKVEDIVTPIMTKLYQQSGAPPPQPD
DKKDDAKTEL*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0016787	hydrolase activity
GO:0016887	ATPase activity
GO:0000166	nucleotide binding
GO:0005524	ATP binding

Vocabulary: **biological process**
Term	Definition
GO:0031333	negative regulation of protein complex assembly
GO:1903895	negative regulation of IRE1-mediated unfolded protein response

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000028	Category 2 cell
PLANA:0000034	epidermis
PLANA:0000035	Category 3 cell
PLANA:0000120	progenitor cell
PLANA:0000136	whole organism
PLANA:0000418	head
PLANA:0000429	neoblast
PLANA:0000484	secretory system
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR042050	BIP_NBD
IPR043129	ATPase_NBD
IPR013126	Hsp_70_fam
IPR029047	HSP70_peptide-bd_sf
IPR029048	HSP70_C_sf
IPR018181	Heat_shock_70_CS
IPR019651	Glutamate_DH_NAD-spec

Vocabulary: **cellular component**
Term	Definition
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 282..309
None	No IPR available	PRINTS	PR00301	HEATSHOCK70	coord: 62..74 score: 80.3 coord: 172..192 score: 87.32 coord: 392..412 score: 69.91 coord: 232..242 score: 79.97 coord: 498..514 score: 75.34 coord: 360..376 score: 78.37 coord: 417..436 score: 74.46 coord: 85..93 score: 65.96 coord: 34..47 score: 82.73
None	No IPR available	GENE3D	G3DSA:3.30.420.40		coord: 214..392 e-value: 7.6E-176 score: 586.3
None	No IPR available	GENE3D	G3DSA:3.30.420.40		coord: 35..405 e-value: 7.6E-176 score: 586.3
None	No IPR available	GENE3D	G3DSA:3.90.640.10		coord: 258..341 e-value: 7.6E-176 score: 586.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 637..660
None	No IPR available	PANTHER	PTHR19375:SF380	ENDOPLASMIC RETICULUM CHAPERONE BIP	coord: 24..647
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..18 score: 0.831
IPR029048	Heat shock protein 70kD, C-terminal domain superfamily	GENE3D	G3DSA:1.20.1270.10		coord: 537..641 e-value: 1.5E-31 score: 110.6
IPR029048	Heat shock protein 70kD, C-terminal domain superfamily	SUPERFAMILY	SSF100934	Heat shock protein 70kD (HSP70), C-terminal subdomain	coord: 564..647
IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily	GENE3D	G3DSA:2.60.34.10		coord: 406..534 e-value: 1.6E-60 score: 204.5
IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily	SUPERFAMILY	SSF100920	Heat shock protein 70kD (HSP70), peptide-binding domain	coord: 413..570
IPR013126	Heat shock protein 70 family	PFAM	PF00012	HSP70	coord: 35..640 e-value: 3.6E-259 score: 861.0
IPR013126	Heat shock protein 70 family	PANTHER	PTHR19375	HEAT SHOCK PROTEIN 70KDA	coord: 24..647
IPR018181	Heat shock protein 70, conserved site	PROSITE	PS00297	HSP70_1	coord: 38..45
IPR018181	Heat shock protein 70, conserved site	PROSITE	PS00329	HSP70_2	coord: 226..239
IPR018181	Heat shock protein 70, conserved site	PROSITE	PS01036	HSP70_3	coord: 363..377
IPR042050	Endoplasmic reticulum chaperone BIP, nucleotide-binding domain	CDD	cd10241	HSPA5-like_NBD	coord: 33..407 e-value: 0.0 score: 788.814
IPR043129	ATPase, nucleotide binding domain	SUPERFAMILY	SSF53067	Actin-like ATPase domain	coord: 220..408
IPR043129	ATPase, nucleotide binding domain	SUPERFAMILY	SSF53067	Actin-like ATPase domain	coord: 33..217