Zinc finger CCCH domain-containing protein 4

Overview


Name	Zinc finger CCCH domain-containing protein 4
Smed ID	SMED30025064
Length (bp)	2499

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Zinc finger CCCH domain-containing protein 4 (SMED30025064) t-SNE clustered cells

Violin plots show distribution of expression levels for Zinc finger CCCH domain-containing protein 4 (SMED30025064) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Zinc finger CCCH domain-containing protein 4 (SMED30025064) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30025064

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
parenchymal cell	SMED30025064	h1SMcG0007031	dd_Smed_v4_10815_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30025064	h1SMcG0007031	dd_Smed_v4_5258_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30025064	h1SMcG0007031	dd_Smed_v4_5258_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
Match: ZC3H6 (zinc finger CCCH-type containing 6 [Source:HGNC Symbol;Acc:HGNC:24762])

HSP 1 Score: 77.0258 bits (188), Expect = 1.020e-13
Identity = 29/64 (45.31%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            KRK +CK+Y  G C  G NC++MH +FPCKF+H   + C  GD+CK+SH  L  + K ++D  +
Sbjct:  302 KRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHS-GAKCYQGDNCKFSHDDLTKETKKLLDKVL 364

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Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            KRK +CK+Y  G C  G NC++MH +FPCKF+H   + C  GD+CK+SH  L  + K ++D  +
Sbjct:  302 KRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHS-GAKCYQGDNCKFSHDDLTKETKKLLDKVL 364

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
Match: ZC3H4 (zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:HGNC:17808])

HSP 1 Score: 74.3294 bits (181), Expect = 6.853e-13
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  +
Sbjct:  420 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKML 482

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
Match: ZC3H4 (zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:HGNC:17808])

HSP 1 Score: 74.3294 bits (181), Expect = 6.999e-13
Identity = 28/66 (42.42%), Postives = 43/66 (65.15%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHE 626
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  + +
Sbjct:  111 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKMLAD 175

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
Match: ZC3H8 (zinc finger CCCH-type containing 8 [Source:HGNC Symbol;Acc:HGNC:30941])

HSP 1 Score: 68.5514 bits (166), Expect = 7.615e-12
Identity = 26/64 (40.62%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K+K +CK+Y  G C  G NCL++H ++PCKF+H   + C  G+ CK+SHAPL  + + ++   +
Sbjct:  221 KKKEMCKFYVQGYCTRGENCLYLHNEYPCKFYHT-GTKCYQGEYCKFSHAPLTPETQELLAKVL 283

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Celegans
Match: T26A8.4 (pep chromosome:WBcel235:IV:8428961:8431493:-1 gene:WBGene00020827.1 transcript:T26A8.4.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T26A8.4)

HSP 1 Score: 64.6994 bits (156), Expect = 1.757e-10
Identity = 25/66 (37.88%), Postives = 40/66 (60.61%), Query Frame = 3

Query:  423 TVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            +++R +LC +YA+  CK G  CL +H +FPCK FH    N    D C++SH PL D  + +++  +
Sbjct:  194 SLRRPVLCNFYANSFCKKGLQCLMLHGEFPCKSFHKGQCN---HDPCRFSHVPLTDYTRPIIEKIL 256

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Fly
Match: su(sable) (gene:FBgn0003575 transcript:FBtr0340081)

HSP 1 Score: 54.6842 bits (130), Expect = 3.844e-7
Identity = 24/61 (39.34%), Postives = 39/61 (63.93%), Query Frame = 3

Query:  432 RKI-LCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHA-PLADDMKTVM 608
            RK+ LCK+Y    C     C +MH++FPCK+++    +C AGDDC + H  PL++ ++ V+
Sbjct:  331 RKLELCKFYLMDCCAKRDKCSYMHKEFPCKYYY-LGMDCYAGDDCLFYHGEPLSEQLRNVL 390

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Fly
Match: su(sable) (gene:FBgn0003575 transcript:FBtr0070120)

HSP 1 Score: 54.6842 bits (130), Expect = 3.879e-7
Identity = 24/61 (39.34%), Postives = 39/61 (63.93%), Query Frame = 3

Query:  432 RKI-LCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHA-PLADDMKTVM 608
            RK+ LCK+Y    C     C +MH++FPCK+++    +C AGDDC + H  PL++ ++ V+
Sbjct:  331 RKLELCKFYLMDCCAKRDKCSYMHKEFPCKYYY-LGMDCYAGDDCLFYHGEPLSEQLRNVL 390

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Fly
Match: su(sable) (gene:FBgn0003575 transcript:FBtr0340082)

HSP 1 Score: 54.6842 bits (130), Expect = 3.879e-7
Identity = 24/61 (39.34%), Postives = 39/61 (63.93%), Query Frame = 3

Query:  432 RKI-LCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHA-PLADDMKTVM 608
            RK+ LCK+Y    C     C +MH++FPCK+++    +C AGDDC + H  PL++ ++ V+
Sbjct:  331 RKLELCKFYLMDCCAKRDKCSYMHKEFPCKYYY-LGMDCYAGDDCLFYHGEPLSEQLRNVL 390

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Zebrafish
Match: zc3h6 (zinc finger CCCH-type containing 6 [Source:ZFIN;Acc:ZDB-GENE-120727-18])

HSP 1 Score: 73.9442 bits (180), Expect = 5.706e-13
Identity = 36/109 (33.03%), Postives = 58/109 (53.21%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQN-RTKCLLPTPEVEPHISQL 743
            V  K+K LCK+Y  G C  G  C+++  ++PCKFFH   + C  GD+CK+SH PL D  K ++D  ++   +         H   + ++N R + + P P+  P +  L
Sbjct:  253 VPEKKKELCKFYVQGYCTKGDICIYILREYPCKFFH-TGAKCYQGDNCKFSHEPLTDVTKELLDKILNTDEET-------VHEDEIELENLRKQGIAPLPKPPPGVGLL 353

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Zebrafish
Match: zc3h4 (zinc finger CCCH-type containing 4 [Source:ZFIN;Acc:ZDB-GENE-100330-1])

HSP 1 Score: 72.7886 bits (177), Expect = 1.399e-12
Identity = 29/66 (43.94%), Postives = 42/66 (63.64%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHE 626
            K+K LCK+Y +G C    NC +MH DFPCK FH  + NC  G++C +SH  L +D + ++D  + E
Sbjct:  392 KKKELCKFYITGFCARAENCPYMHGDFPCKLFH-TTGNCVNGEECMFSHDSLTEDTQELLDKMLAE 456

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BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Xenopus
Match: iqcb1 (IQ motif containing B1 [Source:Xenbase;Acc:XB-GENE-975373])

HSP 1 Score: 77.7962 bits (190), Expect = 6.059e-14
Identity = 30/66 (45.45%), Postives = 43/66 (65.15%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHE 626
            +R+ LCK+Y SG C    NC FMH DFPCK +H  + NC  G+DC +SH PL D+ + +++  + E
Sbjct:  384 RRRGLCKFYVSGYCARAENCPFMHNDFPCKLYH-TTGNCINGEDCMFSHEPLTDETQELLNKILAE 448

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Xenopus
Match: zc3h6 (zinc finger CCCH type containing 6 [Source:NCBI gene;Acc:100124753])

HSP 1 Score: 77.411 bits (189), Expect = 6.621e-14
Identity = 29/65 (44.62%), Postives = 44/65 (67.69%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIH 623
            K++ +CK+Y  G C  G NCL+MH +FPCKF+H   + C  GD+CK+SH PL DD + ++   ++
Sbjct:  296 KKREICKFYIQGYCTKGDNCLYMHNEFPCKFYH-TGAKCYQGDNCKFSHDPLTDDTRELLHKVLN 359

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Xenopus
Match: zc3h6 (zinc finger CCCH type containing 6 [Source:NCBI gene;Acc:100124753])

HSP 1 Score: 61.2326 bits (147), Expect = 7.405e-9
Identity = 24/65 (36.92%), Postives = 39/65 (60.00%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIH 623
            K++ +CK+Y  G C  G NCL+MH      +F+   + C  GD+CK+SH PL DD + ++   ++
Sbjct:  270 KKREICKFYIQGYCTKGDNCLYMHNIL--FYFYHTGAKCYQGDNCKFSHDPLTDDTRELLHKVLN 332

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
Match: Zc3h4 (zinc finger CCCH-type containing 4 [Source:MGI Symbol;Acc:MGI:2682314])

HSP 1 Score: 74.7146 bits (182), Expect = 3.822e-13
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  +
Sbjct:  370 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKML 432

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
Match: Zc3h4 (zinc finger CCCH-type containing 4 [Source:MGI Symbol;Acc:MGI:2682314])

HSP 1 Score: 74.7146 bits (182), Expect = 3.941e-13
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  +
Sbjct:  378 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKML 440

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
Match: Zc3h6 (zinc finger CCCH type containing 6 [Source:MGI Symbol;Acc:MGI:1926001])

HSP 1 Score: 74.3294 bits (181), Expect = 4.709e-13
Identity = 28/64 (43.75%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K+K +CKYY  G C  G NC++MH +FPCKF+H   + C  GD CK+SH  L  + + ++D  +
Sbjct:  300 KKKEVCKYYLQGYCTKGENCIYMHSEFPCKFYHS-GAKCYQGDKCKFSHDDLTKETRKLLDKVL 362

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
Match: Zc3h8 (zinc finger CCCH type containing 8 [Source:MGI Symbol;Acc:MGI:1930128])

HSP 1 Score: 71.2478 bits (173), Expect = 6.939e-13
Identity = 27/64 (42.19%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K+K +CKYY  G C  G NCL++H ++PCKF+H   + C  GD C +SHAPL  + + ++   +
Sbjct:  235 KKKEMCKYYVQGYCTKGENCLYLHSEYPCKFYHT-GTKCYQGDHCNFSHAPLTAETQELLAKVL 297

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Match: sp|P61129|ZC3H6_HUMAN (Zinc finger CCCH domain-containing protein 6 OS=Homo sapiens OX=9606 GN=ZC3H6 PE=1 SV=2)

HSP 1 Score: 77.0258 bits (188), Expect = 4.898e-13
Identity = 29/64 (45.31%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            KRK +CK+Y  G C  G NC++MH +FPCKF+H   + C  GD+CK+SH  L  + K ++D  +
Sbjct:  302 KRKEICKFYLQGYCTKGENCIYMHNEFPCKFYHS-GAKCYQGDNCKFSHDDLTKETKKLLDKVL 364

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Match: sp|Q6ZPZ3|ZC3H4_MOUSE (Zinc finger CCCH domain-containing protein 4 OS=Mus musculus OX=10090 GN=Zc3h4 PE=1 SV=2)

HSP 1 Score: 74.7146 bits (182), Expect = 2.593e-12
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  +
Sbjct:  419 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKML 481

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Match: sp|Q8BYK8|ZC3H6_MOUSE (Zinc finger CCCH domain-containing protein 6 OS=Mus musculus OX=10090 GN=Zc3h6 PE=2 SV=2)

HSP 1 Score: 74.3294 bits (181), Expect = 3.266e-12
Identity = 28/64 (43.75%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K+K +CKYY  G C  G NC++MH +FPCKF+H   + C  GD CK+SH  L  + + ++D  +
Sbjct:  300 KKKEVCKYYLQGYCTKGENCIYMHSEFPCKFYHS-GAKCYQGDKCKFSHDDLTKETRKLLDKVL 362

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Match: sp|Q9UPT8|ZC3H4_HUMAN (Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3)

HSP 1 Score: 74.3294 bits (181), Expect = 3.291e-12
Identity = 28/64 (43.75%), Postives = 42/64 (65.62%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K++ LCK+Y +G C    NC +MH DFPCK +H  + NC  GDDC +SH PL ++ + ++D  +
Sbjct:  420 KKRELCKFYITGFCARAENCPYMHGDFPCKLYH-TTGNCINGDDCMFSHDPLTEETRELLDKML 482

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Match: sp|Q9JJ48|ZC3H8_MOUSE (Zinc finger CCCH domain-containing protein 8 OS=Mus musculus OX=10090 GN=Zc3h8 PE=1 SV=2)

HSP 1 Score: 71.2478 bits (173), Expect = 4.854e-12
Identity = 27/64 (42.19%), Postives = 41/64 (64.06%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K+K +CKYY  G C  G NCL++H ++PCKF+H   + C  GD C +SHAPL  + + ++   +
Sbjct:  235 KKKEMCKYYVQGYCTKGENCLYLHSEYPCKFYHT-GTKCYQGDHCNFSHAPLTAETQELLAKVL 297

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Match: A0A132A0T4 (Uncharacterized protein OS=Sarcoptes scabiei OX=52283 GN=QR98_0030170 PE=4 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 7.804e-14
Identity = 34/67 (50.75%), Postives = 50/67 (74.63%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEG 629
            KRK LCK+Y  G C  G +CLFMH +FPCKFFH  ++ C AG++C++SH PL+D+M+ V+ +++  G
Sbjct:  363 KRKELCKFYLQGFCGKGDDCLFMHSEFPCKFFH-TNTKCYAGENCRFSHKPLSDEMREVLRNYLDSG 428

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Match: A0A443SRM2 (Uncharacterized protein (Fragment) OS=Leptotrombidium deliense OX=299467 GN=B4U80_01604 PE=4 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 1.821e-13
Identity = 31/71 (43.66%), Postives = 50/71 (70.42%), Query Frame = 3

Query:  408 PEENVTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            P ++   K+K +CK+Y  G C  G +CLFMH +FPCKFFH   + C +GD+C++SH PL D+M++++  ++
Sbjct:   18 PHDSPQQKKKDICKFYLQGYCGKGDHCLFMHGEFPCKFFH-TGAECYSGDNCRFSHQPLTDEMRSILKLYL 87

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Match: A0A0R3S937 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS726 PE=4 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 2.634e-13
Identity = 36/76 (47.37%), Postives = 52/76 (68.42%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSN 647
            +  K+K LCK+YA+G C  G  C FMH +FPCKFFH K +NC  G+ CK+SHAPL+ D + +++ ++ E    KS+
Sbjct:  149 IPAKKKDLCKFYAAGSCSKGPACPFMHNEFPCKFFHLK-NNCYHGNTCKFSHAPLSPDSRAMLEKYVEEIEKKKSS 223

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Match: A0A443RAV3 (Uncharacterized protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_13395 PE=4 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 2.004e-12
Identity = 29/68 (42.65%), Postives = 48/68 (70.59%), Query Frame = 3

Query:  426 VKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEG 629
            VK+K +CK+Y  G C  G +CLFMH +FPCKF+H   + C +GD+C++SH PL ++ + ++ +++  G
Sbjct:  425 VKKKDICKFYLQGYCGKGEHCLFMHGEFPCKFYH-TGAECYSGDNCRFSHEPLTEETRAILKAYLDSG 491

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Match: A0A3B4DMI9 (Zinc finger CCCH-type containing 6 OS=Pygocentrus nattereri OX=42514 PE=4 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 2.697e-12
Identity = 38/109 (34.86%), Postives = 62/109 (56.88%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQN-RTKCLLPTPEVEPHISQL 743
            +  K+K LCK+Y  G C  G NC++MH ++PCKFFH   + C  GD+CK+SH PL +  K ++D  ++   DH       +H   + +++ R + + P P+  P +  L
Sbjct:  318 IPEKKKELCKFYVQGYCTKGENCIYMHNEYPCKFFH-TGAKCYQGDNCKFSHDPLTEVTKELLDKILNTDDDH-------AHEDELELEDLRKQGIAPLPKPPPGVGLL 418

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Cavefish
Match: zc3h4 (zinc finger CCCH-type containing 4 [Source:NCBI gene;Acc:103043707])

HSP 1 Score: 79.337 bits (194), Expect = 1.094e-14
Identity = 32/66 (48.48%), Postives = 42/66 (63.64%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHE 626
            K+K LCK+Y +G C    NC +MH DFPCK FH  + NC  GDDC +SH  L DD + ++D  + E
Sbjct:  388 KKKELCKFYITGYCARADNCPYMHGDFPCKLFH-TTGNCVNGDDCMFSHDSLTDDTQELLDKMLAE 452

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Cavefish
Match: zc3h6 (zinc finger CCCH-type containing 6 [Source:ZFIN;Acc:ZDB-GENE-120727-18])

HSP 1 Score: 72.4034 bits (176), Expect = 1.499e-12
Identity = 37/110 (33.64%), Postives = 59/110 (53.64%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFM-HEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQN-RTKCLLPTPEVEPHISQL 743
            V  K+K LCK+Y  G C  G NC++M   ++PCKFFH   + C  GD+CK+SH PL +  K ++   ++   DH       +H   + +++ R   + P P+  P +  L
Sbjct:  314 VPGKKKELCKFYVQGYCTKGENCIYMIANEYPCKFFH-TGAKCYQGDNCKFSHDPLTEITKELLAKILNTDEDH-------AHDDELELEDLRKHGIAPIPKPPPGVGLL 415

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Match: zc3h6 (zinc finger CCCH-type containing 6 [Source:NCBI gene;Acc:101161746])

HSP 1 Score: 75.0998 bits (183), Expect = 2.406e-13
Identity = 31/67 (46.27%), Postives = 43/67 (64.18%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            V  K+K LCK+Y  G C  G +C++MH ++PCKFFH   + C  GD+CK+SH  L D  K ++D  I
Sbjct:  312 VPDKKKELCKFYLQGYCSKGDHCIYMHNEYPCKFFH-TGAKCYQGDNCKFSHDALTDVTKELLDKII 377

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Match: zc3h6 (zinc finger CCCH-type containing 6 [Source:NCBI gene;Acc:101161746])

HSP 1 Score: 75.0998 bits (183), Expect = 2.471e-13
Identity = 31/67 (46.27%), Postives = 43/67 (64.18%), Query Frame = 3

Query:  420 VTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            V  K+K LCK+Y  G C  G +C++MH ++PCKFFH   + C  GD+CK+SH  L D  K ++D  I
Sbjct:  342 VPDKKKELCKFYLQGYCSKGDHCIYMHNEYPCKFFH-TGAKCYQGDNCKFSHDALTDVTKELLDKII 407

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Match: zc3h4 (zinc finger CCCH-type containing 4 [Source:NCBI gene;Acc:101162773])

HSP 1 Score: 72.0182 bits (175), Expect = 1.891e-12
Identity = 29/66 (43.94%), Postives = 42/66 (63.64%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHE 626
            K+K LCK+Y +G C    +C +MH +FPCK FH  + NC  GD+C +SH  L DD + ++D  + E
Sbjct:  393 KKKELCKFYITGFCARADHCPYMHREFPCKLFH-TTGNCVNGDECMFSHEALNDDTQELLDKMLAE 457

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Match: ENSORLT00000030636.1 (zinc finger CCCH domain-containing protein 6 [Source:NCBI gene;Acc:101155004])

HSP 1 Score: 66.6254 bits (161), Expect = 9.197e-11
Identity = 26/62 (41.94%), Postives = 38/62 (61.29%), Query Frame = 3

Query:  435 KILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K +CK+Y  G C  G +C +MH+ FPCK+FH +   C   D C++SH PL +  K ++D  I
Sbjct:  203 KAVCKFYVVGCCIKGESCPYMHKSFPCKYFHQR-GKCLQQDSCRFSHEPLTELTKKLLDEAI 263

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Match: ENSORLT00000028182.1 (zinc finger CCCH domain-containing protein 6 [Source:NCBI gene;Acc:101155004])

HSP 1 Score: 66.6254 bits (161), Expect = 9.414e-11
Identity = 26/62 (41.94%), Postives = 38/62 (61.29%), Query Frame = 3

Query:  435 KILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFI 620
            K +CK+Y  G C  G +C +MH+ FPCK+FH +   C   D C++SH PL +  K ++D  I
Sbjct:  203 KAVCKFYVVGCCIKGESCPYMHKSFPCKYFHQR-GKCLQQDSCRFSHEPLTELTKKLLDEAI 263

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Match: SMESG000044440.1 (SMESG000044440.1)

HSP 1 Score: 1459.12 bits (3776), Expect = 0.000e+0
Identity = 750/754 (99.47%), Postives = 751/754 (99.60%), Query Frame = 3

Query:  177 DENHRTSRRKSSNSPGSRERKRKHYHKLDLNEIKRHRRSSXXXXXXXXXXXXXXLPDYNSNKKPIEIVPELIADIKKPEENVTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQNRTKCLLPTPEVEPHISQLSQTQFHKPVFYSDFCDPEPYEEPLVNNSNHFISRYSNSSMRISYPINKPRLLDQDFRQFPGNFTRKQPDFNTKNNRMPFEPSGNLYVENYRSDFYSTDMAPASPPEINFHEPPSCDIGTSQHHVTPNIPYNNHAPARFIVGNNNNASKPIVDSSMEDEVFKEALKRLADTVTLPDISSNQDSIQKSNFEEQENYSQVKLEKTNPMIYRKNNSTKPTKFVPKDKNGYKSKFITVPPGKPLQSVKKPEPIRMNSNCEENVNPSSIKQENIDYDPFQPHINDEYGPVSSNVIHDKVSYSPAQPNTSQVSYSTFTQEKVSYSPILSNIKQESVSYSPILSNIKQESVSYSPAQPDNITFNTKPETKSYSNVQQVKQSQNTIQAENDKNSIKTEAVAQNIVRIADNVSIFQINENELSESERQYIDEMRSLINLDAQFENKVPWVAVKLQPVLKQPYILFSLKVDQVHENAASDPRLVGHPVLREIETLNDLDEMSSVNDASKNPSRNIAHAXXXXXXXXXXXXXXXXXSGDYLKIDLESSNQPKSPCDTRSYLYNYKVKKENISGQIML 2438
            DENHRTSRRKSSNSPGSRERKRKHYHKLDLNEIKRHRRSSENKEKVEKFIKIEKLPDYNSNKKPIEIVPELIADIKKPEENVTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQNRTKCLLPTPEVEPHISQLSQTQFHKPVFYSDFCDPEPYEEPLVNNSNHFISRYSNSSMRISYPINKPRLLDQDFRQFPGNFTRKQPDFNTKNNRMPFEPSGNLYVENYRSDFYSTDMAPASPPEINFHEPPSCDIGTSQHH TPNIPYNNHAPARFIVGNNNNASKPIVDSSMEDEVFKEALKRLADTVTLPDISSNQDSIQKSNFEEQENYSQVKLEKTNPMIYRKNNSTKPTKFVPKDKNGYKSKFITVPPGKPLQSVKK EPIRMNSNCEENVNPSSIKQENIDYDPFQPHINDEYGPVSSNVIHDKVSYSPAQPNTSQVSYSTFTQEKVSYSPILSNIKQESVSYSPILSNIKQESVSYSPAQPDNITFNTKPETKSYSNVQQVKQSQNTIQAENDKNSIKTEAVAQNIVRIADNVSIFQINENELSESERQYIDEMRSLINLDAQFENKVPWVAVKLQPVLKQPYILFSLKVDQVHENAASDPRLVGHPVLREIETLNDLDEMSSVNDASKNPSRNIAHAENNN+DENEENNENIENS DYLKIDLESSNQPKSPCDTRSYLYNYKVKKENISGQIML
Sbjct:   57 DENHRTSRRKSSNSPGSRERKRKHYHKLDLNEIKRHRRSSENKEKVEKFIKIEKLPDYNSNKKPIEIVPELIADIKKPEENVTVKRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQNRTKCLLPTPEVEPHISQLSQTQFHKPVFYSDFCDPEPYEEPLVNNSNHFISRYSNSSMRISYPINKPRLLDQDFRQFPGNFTRKQPDFNTKNNRMPFEPSGNLYVENYRSDFYSTDMAPASPPEINFHEPPSCDIGTSQHHFTPNIPYNNHAPARFIVGNNNNASKPIVDSSMEDEVFKEALKRLADTVTLPDISSNQDSIQKSNFEEQENYSQVKLEKTNPMIYRKNNSTKPTKFVPKDKNGYKSKFITVPPGKPLQSVKKLEPIRMNSNCEENVNPSSIKQENIDYDPFQPHINDEYGPVSSNVIHDKVSYSPAQPNTSQVSYSTFTQEKVSYSPILSNIKQESVSYSPILSNIKQESVSYSPAQPDNITFNTKPETKSYSNVQQVKQSQNTIQAENDKNSIKTEAVAQNIVRIADNVSIFQINENELSESERQYIDEMRSLINLDAQFENKVPWVAVKLQPVLKQPYILFSLKVDQVHENAASDPRLVGHPVLREIETLNDLDEMSSVNDASKNPSRNIAHAENNNDDENEENNENIENS-DYLKIDLESSNQPKSPCDTRSYLYNYKVKKENISGQIML 809

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Match: SMESG000038705.1 (SMESG000038705.1)

HSP 1 Score: 82.0333 bits (201), Expect = 1.224e-15
Identity = 32/73 (43.84%), Postives = 49/73 (67.12%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSN 647
            K+K LC++Y   +C   SNC +MHE+FPCK FH  S  C +GD CKYSHAPL  + + +++ ++ E  D +++
Sbjct:  758 KKKELCRFYEHQQCYKRSNCSYMHEEFPCKLFHAGSKMCPSGDSCKYSHAPLNQETRALLEKYLDEKVDERTD 830

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Match: SMESG000038705.1 (SMESG000038705.1)

HSP 1 Score: 81.2629 bits (199), Expect = 2.214e-15
Identity = 32/73 (43.84%), Postives = 49/73 (67.12%), Query Frame = 3

Query:  429 KRKILCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSN 647
            K+K LC++Y   +C   SNC +MHE+FPCK FH  S  C +GD CKYSHAPL  + + +++ ++ E  D +++
Sbjct:  758 KKKELCRFYEHQQCYKRSNCSYMHEEFPCKLFHAGSKMCPSGDSCKYSHAPLNQETRALLEKYLDEKVDERTD 830

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Match: SMESG000049281.1 (SMESG000049281.1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.254e-12
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 3

Query:  441 LCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSN-CRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQ 686
            +CKYYA GEC  G  C +MH+ FPC FFH+K  N C  G+ C +SH PL++    ++++ +    +        +    +PVQ
Sbjct:   74 MCKYYAVGECAKGEMCCYMHKTFPCIFFHNKLGNKCNKGEKCLFSHEPLSEAKSVILENHLKNQSNRGKVIEEKASENLIPVQ 156

[Close]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Match: SMESG000033996.1 (SMESG000033996.1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.254e-12
Identity = 30/83 (36.14%), Postives = 46/83 (55.42%), Query Frame = 3

Query:  441 LCKYYASGECKNGSNCLFMHEDFPCKFFHDKSSN-CRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKSNFSAPSHTANVPVQ 686
            +CKYYA GEC  G  C +MH+ FPC FFH+K  N C  G+ C +SH PL++    ++++ +    +        +    +PVQ
Sbjct:   74 MCKYYAVGECAKGEMCCYMHKTFPCIFFHNKLGNKCNKGEKCLFSHEPLSEAKSVILENHLKNQSNRGKVIEEKASENLIPVQ 156

The following BLAST results are available for this feature:

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Celegans
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Fly
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Zebrafish
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Xenopus
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Cavefish
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Sea Lamprey
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Yeast
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Nematostella
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ZC3H6	1.020e-13	45.31	zinc finger CCCH-type containing 6 [Source:HGNC Sy...	[more]
ZC3H6	1.020e-13	45.31	zinc finger CCCH-type containing 6 [Source:HGNC Sy...	[more]
ZC3H4	6.853e-13	43.75	zinc finger CCCH-type containing 4 [Source:HGNC Sy...	[more]
ZC3H4	6.999e-13	42.42	zinc finger CCCH-type containing 4 [Source:HGNC Sy...	[more]
ZC3H8	7.615e-12	40.63	zinc finger CCCH-type containing 8 [Source:HGNC Sy...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
T26A8.4	1.757e-10	37.88	pep chromosome:WBcel235:IV:8428961:8431493:-1 gene...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3


Match Name	E-value	Identity	Description
su(sable)	3.844e-7	39.34	gene:FBgn0003575 transcript:FBtr0340081	[more]
su(sable)	3.879e-7	39.34	gene:FBgn0003575 transcript:FBtr0070120	[more]
su(sable)	3.879e-7	39.34	gene:FBgn0003575 transcript:FBtr0340082	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
zc3h6	5.706e-13	33.03	zinc finger CCCH-type containing 6 [Source:ZFIN;Ac...	[more]
zc3h4	1.399e-12	43.94	zinc finger CCCH-type containing 4 [Source:ZFIN;Ac...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3


Match Name	E-value	Identity	Description
iqcb1	6.059e-14	45.45	IQ motif containing B1 [Source:Xenbase;Acc:XB-GENE...	[more]
zc3h6	6.621e-14	44.62	zinc finger CCCH type containing 6 [Source:NCBI ge...	[more]
zc3h6	7.405e-9	36.92	zinc finger CCCH type containing 6 [Source:NCBI ge...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Zc3h4	3.822e-13	43.75	zinc finger CCCH-type containing 4 [Source:MGI Sym...	[more]
Zc3h4	3.941e-13	43.75	zinc finger CCCH-type containing 4 [Source:MGI Sym...	[more]
Zc3h6	4.709e-13	43.75	zinc finger CCCH type containing 6 [Source:MGI Sym...	[more]
Zc3h8	6.939e-13	42.19	zinc finger CCCH type containing 8 [Source:MGI Sym...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P61129\|ZC3H6_HUMAN	4.898e-13	45.31	Zinc finger CCCH domain-containing protein 6 OS=Ho...	[more]
sp\|Q6ZPZ3\|ZC3H4_MOUSE	2.593e-12	43.75	Zinc finger CCCH domain-containing protein 4 OS=Mu...	[more]
sp\|Q8BYK8\|ZC3H6_MOUSE	3.266e-12	43.75	Zinc finger CCCH domain-containing protein 6 OS=Mu...	[more]
sp\|Q9UPT8\|ZC3H4_HUMAN	3.291e-12	43.75	Zinc finger CCCH domain-containing protein 4 OS=Ho...	[more]
sp\|Q9JJ48\|ZC3H8_MOUSE	4.854e-12	42.19	Zinc finger CCCH domain-containing protein 8 OS=Mu...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A132A0T4	7.804e-14	50.75	Uncharacterized protein OS=Sarcoptes scabiei OX=52...	[more]
A0A443SRM2	1.821e-13	43.66	Uncharacterized protein (Fragment) OS=Leptotrombid...	[more]
A0A0R3S937	2.634e-13	47.37	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A443RAV3	2.004e-12	42.65	Uncharacterized protein OS=Dinothrombium tinctoriu...	[more]
A0A3B4DMI9	2.697e-12	34.86	Zinc finger CCCH-type containing 6 OS=Pygocentrus ...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
zc3h4	1.094e-14	48.48	zinc finger CCCH-type containing 4 [Source:NCBI ge...	[more]
zc3h6	1.499e-12	33.64	zinc finger CCCH-type containing 6 [Source:ZFIN;Ac...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zc3h6	2.406e-13	46.27	zinc finger CCCH-type containing 6 [Source:NCBI ge...	[more]
zc3h6	2.471e-13	46.27	zinc finger CCCH-type containing 6 [Source:NCBI ge...	[more]
zc3h4	1.891e-12	43.94	zinc finger CCCH-type containing 4 [Source:NCBI ge...	[more]
ENSORLT00000030636.1	9.197e-11	41.94	zinc finger CCCH domain-containing protein 6 [Sour...	[more]
ENSORLT00000028182.1	9.414e-11	41.94	zinc finger CCCH domain-containing protein 6 [Sour...	[more]

BLAST of Zinc finger CCCH domain-containing protein 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000044440.1	0.000e+0	99.47	SMESG000044440.1	[more]
SMESG000038705.1	1.224e-15	43.84	SMESG000038705.1	[more]
SMESG000038705.1	2.214e-15	43.84	SMESG000038705.1	[more]
SMESG000049281.1	1.254e-12	36.14	SMESG000049281.1	[more]
SMESG000033996.1	1.254e-12	36.14	SMESG000033996.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30025064 ID=SMED30025064|Name=Zinc finger CCCH domain-containing protein 4|organism=Schmidtea mediterranea sexual|type=transcript|length=2499bp
AAAAAATGAAATTATTTAACGTTTTCAAATCGATTATCAGAGCGGCCATT
GTTAATTTGGAAGTGAAAAGTTGCTATTTATAGATTTCTAGCGTTATCAT
AGTGGATTTTTTTTGCAATTTTTTTAAATGATGGATTTGATTACGTTTCA
ATAATTAATCTAATGATTTCTGTTAGGATGAAAACCACAGAACTAGTAGA
AGGAAATCTAGCAATAGTCCCGGTTCACGAGAAAGAAAACGGAAGCATTA
TCATAAATTGGATTTGAATGAAATTAAAAGGCATAGGAGATCGAGTGAAA
ACAAAGAAAAAGTCGAGAAATTTATTAAAATCGAAAAGTTACCAGATTAT
AATTCCAATAAAAAACCCATCGAAATTGTGCCGGAATTAATTGCCGACAT
AAAGAAGCCCGAAGAAAATGTAACTGTAAAACGGAAAATCCTTTGTAAAT
ATTACGCGAGTGGTGAATGCAAAAACGGTTCAAATTGTCTGTTTATGCAC
GAGGATTTCCCCTGTAAATTTTTCCATGATAAATCGTCAAATTGCCGGGC
AGGAGACGACTGTAAGTATTCCCACGCGCCATTGGCAGATGACATGAAGA
CCGTTATGGACAGTTTTATTCACGAAGGAAGAGATCACAAATCCAATTTC
TCGGCTCCTAGTCACACGGCGAATGTTCCAGTTCAAAATCGAACAAAATG
CCTTCTCCCTACTCCCGAAGTTGAGCCACACATATCCCAATTAAGTCAAA
CCCAGTTTCATAAACCAGTATTTTATAGCGATTTTTGTGATCCAGAACCA
TATGAGGAACCGTTAGTCAACAACTCGAATCATTTTATATCTCGTTATTC
TAACTCATCAATGAGAATTTCATATCCAATAAATAAACCGAGACTACTTG
ATCAAGATTTTAGACAATTTCCAGGAAACTTTACTAGGAAGCAGCCTGAT
TTTAATACTAAAAACAATCGTATGCCTTTTGAACCGAGCGGTAACTTGTA
TGTGGAAAATTATCGCAGCGATTTCTATTCCACAGATATGGCACCCGCAT
CACCTCCTGAAATCAATTTTCATGAACCCCCATCATGTGATATAGGTACA
AGCCAGCACCATGTTACCCCAAACATCCCCTACAACAATCACGCACCTGC
TCGCTTCATTGTCGGTAACAATAACAACGCTTCTAAGCCTATTGTTGATT
CAAGTATGGAGGATGAGGTGTTTAAAGAGGCATTAAAACGTTTGGCAGAC
ACAGTCACTCTCCCTGATATCTCATCAAATCAAGATAGTATTCAGAAGTC
GAATTTTGAAGAACAGGAAAACTATAGTCAAGTAAAACTAGAGAAAACCA
ATCCAATGATTTATCGCAAAAATAATTCCACAAAACCAACAAAATTTGTC
CCGAAAGATAAAAATGGATATAAATCAAAATTTATAACTGTTCCACCCGG
TAAACCATTACAAAGCGTTAAGAAACCAGAACCAATACGAATGAACTCAA
ATTGCGAAGAAAATGTAAATCCAAGTTCAATAAAACAAGAAAATATAGAT
TATGACCCCTTTCAACCACATATAAATGATGAATACGGCCCCGTTTCATC
AAATGTCATCCATGACAAAGTCTCATACAGTCCAGCTCAACCGAATACTA
GTCAGGTTTCCTACAGTACATTTACCCAGGAAAAAGTCTCATATAGTCCG
ATATTATCTAATATCAAACAGGAATCCGTCTCATACAGTCCGATACTGTC
TAATATCAAACAGGAATCCGTCTCATACAGTCCAGCGCAACCGGACAATA
TAACATTCAATACTAAACCAGAAACTAAATCGTACAGTAACGTTCAACAG
GTTAAACAGTCCCAGAATACAATACAAGCAGAAAACGATAAAAACAGCAT
TAAAACGGAAGCAGTTGCTCAAAATATTGTTAGAATCGCTGACAACGTCT
CAATATTTCAAATCAATGAAAACGAACTAAGCGAATCCGAACGACAATAT
ATTGACGAAATGAGAAGTTTGATTAATCTCGACGCGCAATTTGAAAATAA
AGTCCCGTGGGTTGCTGTGAAGCTTCAGCCGGTTTTAAAGCAGCCATACA
TTTTGTTCAGCTTAAAAGTCGATCAGGTCCATGAGAATGCAGCGTCTGAT
CCGCGCTTAGTCGGCCATCCTGTACTTAGGGAAATTGAAACGTTGAATGA
TCTGGATGAAATGTCCTCTGTCAATGATGCCAGCAAGAACCCTAGCCGTA
ATATCGCACATGCTGAAAACAATAACAATGATGAAAACGAAGAGAACAAT
GAGAACATCGAGAACAGTGGTGATTACCTTAAGATCGACTTGGAATCATC
GAATCAACCGAAGTCTCCTTGTGATACCCGTTCATATTTGTACAATTATA
AAGTGAAAAAAGAAAATATTTCTGGACAAATAATGTTGTAATTCAGTATT
TATACGTTACTTTTCAGATGTTATTTTTTATAAATAAATGTATCTATTG

protein sequence of SMED30025064-orf-1

>SMED30025064-orf-1 ID=SMED30025064-orf-1|Name=SMED30025064-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=649bp
MHEDFPCKFFHDKSSNCRAGDDCKYSHAPLADDMKTVMDSFIHEGRDHKS
NFSAPSHTANVPVQNRTKCLLPTPEVEPHISQLSQTQFHKPVFYSDFCDP
EPYEEPLVNNSNHFISRYSNSSMRISYPINKPRLLDQDFRQFPGNFTRKQ
PDFNTKNNRMPFEPSGNLYVENYRSDFYSTDMAPASPPEINFHEPPSCDI
GTSQHHVTPNIPYNNHAPARFIVGNNNNASKPIVDSSMEDEVFKEALKRL
ADTVTLPDISSNQDSIQKSNFEEQENYSQVKLEKTNPMIYRKNNSTKPTK
FVPKDKNGYKSKFITVPPGKPLQSVKKPEPIRMNSNCEENVNPSSIKQEN
IDYDPFQPHINDEYGPVSSNVIHDKVSYSPAQPNTSQVSYSTFTQEKVSY
SPILSNIKQESVSYSPILSNIKQESVSYSPAQPDNITFNTKPETKSYSNV
QQVKQSQNTIQAENDKNSIKTEAVAQNIVRIADNVSIFQINENELSESER
QYIDEMRSLINLDAQFENKVPWVAVKLQPVLKQPYILFSLKVDQVHENAA
SDPRLVGHPVLREIETLNDLDEMSSVNDASKNPSRNIAHAENNNNDENEE
NNENIENSGDYLKIDLESSNQPKSPCDTRSYLYNYKVKKENISGQIML*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036855	Znf_CCCH_sf
IPR000571	Znf_CCCH

Vocabulary: **molecular function**
Term	Definition
GO:0046872	metal ion binding
GO:0003674	molecular_function

Vocabulary: **cellular component**
Term	Definition
GO:0005575	cellular_component

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 587..607
None	No IPR available	GENE3D	G3DSA:4.10.1000.10		coord: 1..59 e-value: 4.4E-10 score: 41.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 572..589
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 572..602
IPR000571	Zinc finger, CCCH-type	PROSITE	PS50103	ZF_C3H1	coord: 6..30 score: 12.868
IPR036855	Zinc finger, CCCH-type superfamily	SUPERFAMILY	SSF90229	CCCH zinc finger	coord: 5..46

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Zinc finger CCCH domain-containing protein 4

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Owlery

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