FCH and double SH3 domains protein

Overview
NameFCH and double SH3 domains protein
Smed IDSMED30025026
Length (bp)2767
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of FCH and double SH3 domains protein (SMED30025026) t-SNE clustered cells

Violin plots show distribution of expression levels for FCH and double SH3 domains protein (SMED30025026) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of FCH and double SH3 domains protein (SMED30025026) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for FCH and double SH3 domains protein (SMED30025026) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025026

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 9

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30025026h1SMcG0007958 SmedASXL_016851SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior sideSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
posterior muscle cellSMED30025026h1SMcG0007958 dd_Smed_v4_13998_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30025026h1SMcG0007958 dd_Smed_v6_13998_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Match: FCHSD2 (FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114])

HSP 1 Score: 165.622 bits (418), Expect = 1.058e-41
Identity = 141/425 (33.18%), Postives = 214/425 (50.35%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDL-NVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ MQKL    L KR +P     K +D  D  +++  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V+++ K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     +++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK + +++ V          +       AA SE    +L        E K++E +  IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:   17 IQVEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKLASQYL-KRDWPG---VKADDRNDYRSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRV----------LNDLECHGAAVSEQSRAEL--------EQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 413
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Match: FCHSD2 (FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114])

HSP 1 Score: 160.614 bits (405), Expect = 6.090e-40
Identity = 105/300 (35.00%), Postives = 163/300 (54.33%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDL-NVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGD 1069
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ MQKL    L KR +P     K +D  D  +++  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V+++ K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     +++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D
Sbjct:   17 IQVEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKLASQYL-KRDWPG---VKADDRNDYRSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSD 307
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Match: FCHSD2 (FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114])

HSP 1 Score: 123.25 bits (308), Expect = 9.564e-29
Identity = 120/385 (31.17%), Postives = 186/385 (48.31%), Query Frame = 2 
Query:  299 MQKLILNLLAKRHFPAKENCKENDSEDL-NVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            MQKL    L KR +P     K +D  D  +++  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V+++ K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     +++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK + +++ V          +       AA SE    +L        E K++E +  IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:    1 MQKLASQYL-KRDWPG---VKADDRNDYRSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRV----------LNDLECHGAAVSEQSRAEL--------EQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 357
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Match: FCHSD2 (FCH and double SH3 domains 2 [Source:HGNC Symbol;Acc:HGNC:29114])

HSP 1 Score: 124.405 bits (311), Expect = 1.410e-28
Identity = 120/385 (31.17%), Postives = 186/385 (48.31%), Query Frame = 2 
Query:  299 MQKLILNLLAKRHFPAKENCKENDSEDL-NVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            MQKL    L KR +P     K +D  D  +++  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V+++ K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     +++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK + +++ V          +       AA SE    +L        E K++E +  IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:    1 MQKLASQYL-KRDWPG---VKADDRNDYRSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRV----------LNDLECHGAAVSEQSRAEL--------EQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 357
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Match: FCHSD1 (FCH and double SH3 domains 1 [Source:HGNC Symbol;Acc:HGNC:25463])

HSP 1 Score: 122.094 bits (305), Expect = 6.798e-28
Identity = 115/436 (26.38%), Postives = 206/436 (47.25%), Query Frame = 2 
Query:  203 LQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWE----IFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVT--KKLVKRLI---VREHKIMGYEKEV-KSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSE 1480
            LQ     + DL+EDIR + KQ+AA +REY Q++QKL    L +          E DS    V+  WR LL+        RL  +D  + L+      R  +    ++  + L+  Q ++   V+E+ +++K+Y + E+     + KA D   ++      IF+S  +L K S KLS++   Y  +  AARNEYL  L A NAHL  Y+  +L    + + +++ +  ++ L +++  E    ++ ++V L+   + E+   +  WE    +FL     F+     +FQ    D++ +   L      +A  +  +K V+RL     R++KI  +   V +  E  R    Q A+   A                 +E +++E++ +IR+ ++ + K  A L LL+ +G+D ++ L  A T   A  E+ ++ R SE
Sbjct:   25 LQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKRE----GHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG--RSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTE----LEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCV---LEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRR----QQASEREAPS---------------IEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQ--AQDEVEQERRLSE 426
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0344238)

HSP 1 Score: 167.162 bits (422), Expect = 5.086e-42
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420

HSP 2 Score: 67.0106 bits (162), Expect = 7.951e-11
Identity = 54/182 (29.67%), Postives = 85/182 (46.70%), Query Frame = 2 
Query: 1802 RAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVL--PISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRK 2341
            +  A++ + A +   +EL +V NE++ ++   + DGW++ R+   G EG VP +YL      I Q       N    D     D V+V+  P  +VKS              +     Y + +T  DEL  E+ D I+II++ +  GVDDGWWEG            +  + G FPS+VV +
Sbjct:  546 KCTALYSYTAQNP--DELTIVENEQLEVVGEGDGDGWLRARNYR-GEEGYVPHNYLD-----IDQETAGSAFNDQTVDSMQSPDQVSVIMAPQKRVKSD------------VEWCIALYDYDATAEDELTFEEGDKIKIITKTAH-GVDDGWWEGE-----------LDGKFGNFPSLVVEE 695
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0309276)

HSP 1 Score: 167.162 bits (422), Expect = 6.090e-42
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420

HSP 2 Score: 66.6254 bits (161), Expect = 1.024e-10
Identity = 54/182 (29.67%), Postives = 85/182 (46.70%), Query Frame = 2 
Query: 1802 RAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVL--PISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRK 2341
            +  A++ + A +   +EL +V NE++ ++   + DGW++ R+   G EG VP +YL      I Q       N    D     D V+V+  P  +VKS              +     Y + +T  DEL  E+ D I+II++ +  GVDDGWWEG            +  + G FPS+VV +
Sbjct:  546 KCTALYSYTAQNP--DELTIVENEQLEVVGEGDGDGWLRARNYR-GEEGYVPHNYLD-----IDQETAGSAFNDQTVDSMQSPDQVSVIMAPQKRVKSD------------VEWCIALYDYDATAEDELTFEEGDKIKIITKTAH-GVDDGWWEGE-----------LDGKFGNFPSLVVEE 695
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0344242)

HSP 1 Score: 166.777 bits (421), Expect = 6.899e-42
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420

HSP 2 Score: 66.2402 bits (160), Expect = 1.128e-10
Identity = 54/182 (29.67%), Postives = 85/182 (46.70%), Query Frame = 2 
Query: 1802 RAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVL--PISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRK 2341
            +  A++ + A +   +EL +V NE++ ++   + DGW++ R+   G EG VP +YL      I Q       N    D     D V+V+  P  +VKS              +     Y + +T  DEL  E+ D I+II++ +  GVDDGWWEG            +  + G FPS+VV +
Sbjct:  546 KCTALYSYTAQNP--DELTIVENEQLEVVGEGDGDGWLRARNYR-GEEGYVPHNYLD-----IDQETAGSAFNDQTVDSMQSPDQVSVIMAPQKRVKSD------------VEWCIALYDYDATAEDELTFEEGDKIKIITKTAH-GVDDGWWEGE-----------LDGKFGNFPSLVVEE 695
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0309277)

HSP 1 Score: 166.007 bits (419), Expect = 7.530e-42
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Match: nwk (gene:FBgn0263456 transcript:FBtr0309280)

HSP 1 Score: 166.007 bits (419), Expect = 9.153e-42
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Match: si:ch211-176g13.8 (si:ch211-176g13.8 [Source:ZFIN;Acc:ZDB-GENE-091204-303])

HSP 1 Score: 139.428 bits (350), Expect = 1.619e-33
Identity = 115/421 (27.32%), Postives = 208/421 (49.41%), Query Frame = 2 
Query:  188 EHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTAD-LLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLN--LKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            E    LQ KH +D D +ED+R + ++KA  +++Y+Q++ KL    L KR +    + +  DS   N+W+ WR  L    + +  R+N  +    ++SD +K  R  +    KR  +QL   Q DL   ++++ K++K Y E E+ +  +R KA+  A+       ++F S ++L + S KL ++ + +++++T +RN+YL  L+A NAH   Y+  DL    +++D   YD  +  L+ +   E   S      +  L++ S  + ++ H +IF+ +   F     +++Q  + D +  L+  +   +E++L    +K   R + REHK I+  ++ +  +E                    G+      N E +E K+++ K  IRK +  K K EA L LL+D GV  D  L  A   V
Sbjct:   20 EQLNRLQLKHQTDLDFLEDLRTYSQKKALIEKDYSQALHKLASQYL-KREWTGAPSEEPRDSR--NIWAVWRSYLEGVMKVSQSRINRCENYRSQISDPVKTFRTQKDLQLKRCSEQLSRAQADLQGTIRDLEKSRKTYQEAEQTSQSVREKAEMEAKS----RLSLFQSRSSLKRASVKLKAKKNEWKSKATQSRNDYLLALSATNAHQDRYYETDLISCIRVLDGGFYDHAQGFLIWLCQTELETSQSIQDTFQSLLETSSSVTQETHQQIFIQDNAVFQKAAPFQYQPGENDSVRELLKESGTAEEHSLNKEARKWATR-VAREHKNIILTQRTLSEYE--------------------GLHQQDQNNNE-LELKMDDAKECIRKSETVKLKAEARLNLLRDVGVAVDVWLKSATNQV 411
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Match: srgap1a (SLIT-ROBO Rho GTPase activating protein 1a [Source:ZFIN;Acc:ZDB-GENE-050420-284])

HSP 1 Score: 68.5514 bits (166), Expect = 3.173e-11
Identity = 71/300 (23.67%), Postives = 139/300 (46.33%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADL---------LQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQ-------EMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTN-IFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKS-EKICRKYHWEIFLNNYPS-FNAPVQYKFQSVKGDKI 1075
            L++D++ F ++K+  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +D+         +Q   D  + ++ ++  T +   D +K+L  +LYT ++       E I A+    E EKQ  +   +  D    ++ +  +   +S+  + K   K  ++    + +S  ARNEYL  L A NA +F Y+  DL D     D   +      L T  + E N    + +  L +I+ + + +  +   + F+  YP+ F  PV+++FQ+  GD++
Sbjct:   49 LLQDLQDFFRKKSEIEMEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRLMKKSKEITFQLQEDLMKVL-NELYTVMKTYHMYHTESISAEGKLKEAEKQEEKQIGRVGDPVFHIRLEDRHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASIFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEYNLETSRHE-GLDIIENAVDSLDPRSDRQRFMEMYPTAFCPPVKFEFQAHMGDEV 346
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Match: srgap1b (SLIT-ROBO Rho GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-041210-103])

HSP 1 Score: 65.4698 bits (158), Expect = 2.847e-10
Identity = 74/307 (24.10%), Postives = 128/307 (41.69%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLST-NKRILDQLK----LLQTDLYTCVQEMIKAQKVYS--EEEKQAHEIRIK-AQDAAEKVKNKSTNIF-----------NSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYP-SFNAPVQYKFQSVKGDKIHLLVPL 1093
            L++D++ F ++KA  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +DL   L++ +   R   +S  N R+L + K     LQ DL   + E+    K Y     E  + E ++K A+   E+       +F           N+   + K   K  ++    + +   ARNEYL  L A NA LF Y+  DL       D   +      L T  + E +    + +    L    E +      + F+  +P SF  P ++ FQ   GD++  +  L
Sbjct:   45 LLQDLQDFFRKKAEIESEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDLY--LNNVI--TRFTHVSEDNMRLLKKSKEIIFQLQEDLMKILNELYTVMKTYHMYHTETLSAENKLKEAERQGERQGRGGEAVFSLRTEDRHQRRNAARKIQKMKEKRQAKYSENKLKVMKARNEYLLTLEATNASLFKYYIHDLSHLTDCCDLGYHAGLSRALRTYLSAEYSLETSRHEGLDILEGAVEGLDPGNDRQRFMETHPTSFTPPTRFTFQPHMGDQVSQITAL 347
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Match: srgap1b (SLIT-ROBO Rho GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-041210-103])

HSP 1 Score: 65.4698 bits (158), Expect = 2.936e-10
Identity = 74/307 (24.10%), Postives = 128/307 (41.69%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLST-NKRILDQLK----LLQTDLYTCVQEMIKAQKVYS--EEEKQAHEIRIK-AQDAAEKVKNKSTNIF-----------NSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYP-SFNAPVQYKFQSVKGDKIHLLVPL 1093
            L++D++ F ++KA  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +DL   L++ +   R   +S  N R+L + K     LQ DL   + E+    K Y     E  + E ++K A+   E+       +F           N+   + K   K  ++    + +   ARNEYL  L A NA LF Y+  DL       D   +      L T  + E +    + +    L    E +      + F+  +P SF  P ++ FQ   GD++  +  L
Sbjct:   45 LLQDLQDFFRKKAEIESEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDLY--LNNVI--TRFTHVSEDNMRLLKKSKEIIFQLQEDLMKILNELYTVMKTYHMYHTETLSAENKLKEAERQGERQGRGGEAVFSLRTEDRHQRRNAARKIQKMKEKRQAKYSENKLKVMKARNEYLLTLEATNASLFKYYIHDLSHLTDCCDLGYHAGLSRALRTYLSAEYSLETSRHEGLDILEGAVEGLDPGNDRQRFMETHPTSFTPPTRFTFQPHMGDQVSQITAL 347
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Match: CABZ01070631.2 (F-BAR and double SH3 domains protein 2-like [Source:NCBI gene;Acc:100537850])

HSP 1 Score: 54.299 bits (129), Expect = 7.822e-8
Identity = 37/113 (32.74%), Postives = 63/113 (55.75%), Query Frame = 2 
Query:  176 QIQNEHFIDLQK---KHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPA-KENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRI 499
            +++N H   L +   KH ++ DL+ED+R + ++KA  +R+YAQ++QKL    L KR +P  K + +  D    NV+  WR  L    +    RLN  D  + +++D  K +R+
Sbjct:   13 ELKNTHVEQLGRLHLKHQTECDLLEDMRTYSQKKATLERDYAQALQKLASQYL-KRDWPGIKPDDQRTDYR--NVYGVWRAYLEGTVQVTQSRLNVCDNYKNEITDPAKTVRL 122
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Match: tmem209 (transmembrane protein 209 [Source:Xenbase;Acc:XB-GENE-976000])

HSP 1 Score: 154.451 bits (389), Expect = 4.639e-38
Identity = 134/450 (29.78%), Postives = 223/450 (49.56%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKL-SDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQ-DAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPL--------------------------NLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            I +E    LQ KH ++ DL+ED+R F ++KAA +REYAQ++QKL    L K+ +PA +   +  SE  ++++ W+  L    +    ++N  +  + L S+  + +++ +    KR +DQL  +Q +L   V+++ KA+K Y E E+ AH +R KA  DA  K+     ++F S  +L K + KL +R      ++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+ ++  E + C   Q+  +  L++ S ++ R Y+ ++F+     F+    ++FQ    D     VPL                            +E++L    +K   R + REHK I+  ++ ++  E  + TP+          SE    +L        E K+EE +  +RK +I K K EA L LL+  GV  D  L  A   V
Sbjct:   17 IHSEQMTKLQAKHQAECDLLEDMRTFSQKKAAVEREYAQTIQKLASQYL-KKEWPAVK--PDERSEYRSIYTVWKSFLEGTMQVTQSQINICENYKNLISEPARTVKLYKEQQLKRCVDQLTKIQAELQETVKDLAKAKKKYYEAEQMAHAMREKADIDAKSKL-----SLFQSRISLQKANVKLKARRSECNAKATHARNDYLLTLAAANAHQDRYYQTDLANAMKALDGNVYDHLKDYLMALSRTELEKCQAVQN-TFQYLLETSSRVMRDYNLQLFVQENLVFHKAQPFQFQPCDSDTSFSAVPLVDIEPSPVSAMRMILAKSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIIHSQRALEELEC-QTTPV----------SEQSRMEL--------EQKIEETRENMRKAEITKLKAEARLDLLRQIGVSVDTWLKSAMNQV 437
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Match: tmem209 (transmembrane protein 209 [Source:Xenbase;Acc:XB-GENE-976000])

HSP 1 Score: 154.451 bits (389), Expect = 4.725e-38
Identity = 134/450 (29.78%), Postives = 223/450 (49.56%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKL-SDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQ-DAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPL--------------------------NLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            I +E    LQ KH ++ DL+ED+R F ++KAA +REYAQ++QKL    L K+ +PA +   +  SE  ++++ W+  L    +    ++N  +  + L S+  + +++ +    KR +DQL  +Q +L   V+++ KA+K Y E E+ AH +R KA  DA  K+     ++F S  +L K + KL +R      ++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+ ++  E + C   Q+  +  L++ S ++ R Y+ ++F+     F+    ++FQ    D     VPL                            +E++L    +K   R + REHK I+  ++ ++  E  + TP+          SE    +L        E K+EE +  +RK +I K K EA L LL+  GV  D  L  A   V
Sbjct:   27 IHSEQMTKLQAKHQAECDLLEDMRTFSQKKAAVEREYAQTIQKLASQYL-KKEWPAVK--PDERSEYRSIYTVWKSFLEGTMQVTQSQINICENYKNLISEPARTVKLYKEQQLKRCVDQLTKIQAELQETVKDLAKAKKKYYEAEQMAHAMREKADIDAKSKL-----SLFQSRISLQKANVKLKARRSECNAKATHARNDYLLTLAAANAHQDRYYQTDLANAMKALDGNVYDHLKDYLMALSRTELEKCQAVQN-TFQYLLETSSRVMRDYNLQLFVQENLVFHKAQPFQFQPCDSDTSFSAVPLVDIEPSPVSAMRMILAKSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIIHSQRALEELEC-QTTPV----------SEQSRMEL--------EQKIEETRENMRKAEITKLKAEARLDLLRQIGVSVDTWLKSAMNQV 447
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Match: tmem209 (transmembrane protein 209 [Source:Xenbase;Acc:XB-GENE-976000])

HSP 1 Score: 154.066 bits (388), Expect = 6.132e-38
Identity = 134/450 (29.78%), Postives = 223/450 (49.56%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKL-SDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQ-DAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPL--------------------------NLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            I +E    LQ KH ++ DL+ED+R F ++KAA +REYAQ++QKL    L K+ +PA +   +  SE  ++++ W+  L    +    ++N  +  + L S+  + +++ +    KR +DQL  +Q +L   V+++ KA+K Y E E+ AH +R KA  DA  K+     ++F S  +L K + KL +R      ++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+ ++  E + C   Q+  +  L++ S ++ R Y+ ++F+     F+    ++FQ    D     VPL                            +E++L    +K   R + REHK I+  ++ ++  E  + TP+          SE    +L        E K+EE +  +RK +I K K EA L LL+  GV  D  L  A   V
Sbjct:   16 IHSEQMTKLQAKHQAECDLLEDMRTFSQKKAAVEREYAQTIQKLASQYL-KKEWPAVK--PDERSEYRSIYTVWKSFLEGTMQVTQSQINICENYKNLISEPARTVKLYKEQQLKRCVDQLTKIQAELQETVKDLAKAKKKYYEAEQMAHAMREKADIDAKSKL-----SLFQSRISLQKANVKLKARRSECNAKATHARNDYLLTLAAANAHQDRYYQTDLANAMKALDGNVYDHLKDYLMALSRTELEKCQAVQN-TFQYLLETSSRVMRDYNLQLFVQENLVFHKAQPFQFQPCDSDTSFSAVPLVDIEPSPVSAMRMILAKSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIIHSQRALEELEC-QTTPV----------SEQSRMEL--------EQKIEETRENMRKAEITKLKAEARLDLLRQIGVSVDTWLKSAMNQV 436
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Match: tmem209 (transmembrane protein 209 [Source:Xenbase;Acc:XB-GENE-976000])

HSP 1 Score: 150.599 bits (379), Expect = 7.651e-37
Identity = 133/436 (30.50%), Postives = 221/436 (50.69%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKL-SDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQ-DAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQ----------SQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            I +E    LQ KH ++ DL+ED+R F ++KAA +REYAQ++QKL    L K+ +PA +   +  SE  ++++ W+  L    +    ++N  +  + L S+  + +++ +    KR +DQL  +Q +L   V+++ KA+K Y E E+ AH +R KA  DA  K+     ++F S  +L K + KL +R      ++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+ ++  E + C   Q          S+ +++L K    + R Y+ ++F+     F+    ++FQ    D    L       +E++L    +K   R + REHK I+  ++ ++  E  + TP+          SE    +L        E K+EE +  +RK +I K K EA L LL+  GV  D  L  A   V
Sbjct:   27 IHSEQMTKLQAKHQAECDLLEDMRTFSQKKAAVEREYAQTIQKLASQYL-KKEWPAVK--PDERSEYRSIYTVWKSFLEGTMQVTQSQINICENYKNLISEPARTVKLYKEQQLKRCVDQLTKIQAELQETVKDLAKAKKKYYEAEQMAHAMREKADIDAKSKL-----SLFQSRISLQKANVKLKARRSECNAKATHARNDYLLTLAAANAHQDRYYQTDLANAMKALDGNVYDHLKDYLMALSRTELEKCQAVQNTFQYLLETSSRAFMQL-KFPSSVMRDYNLQLFVQENLVFHKAQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIIHSQRALEELEC-QTTPV----------SEQSRMEL--------EQKIEETRENMRKAEITKLKAEARLDLLRQIGVSVDTWLKSAMNQV 433
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Match: cilp2 (cartilage intermediate layer protein 2 [Source:Xenbase;Acc:XB-GENE-6044552])

HSP 1 Score: 135.961 bits (341), Expect = 2.256e-32
Identity = 143/497 (28.77%), Postives = 234/497 (47.08%), Query Frame = 2 
Query:  185 NEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKL-SDQLKPIRINRLSTNKRI--LDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIID---ADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLI---VREHKIMGY-EKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYXXXXXXXXXXXXXDNPDYDE--------ELSQINNEESFPYSLSKYSGYEYQ 1621
             E    LQ K L DT+L+EDIR FCKQ+AA ++EY Q +  L ++L+        E C        +V+S WR ++         R+  A+  + L S+  K  R  +    K++  ++QL  +Q +L   ++E+ K +K Y + E+ +   + KA D   ++K    +IF+S A+L K S K S+++     + + ARNEYL  L A NAHL  Y+   L D   + +    D+YDR ++ L  I+  E N      + +  ++  S+++ R+ + ++FL +   F+  +  KFQ    DK+  L  L    N + +V  K  +R      R++K+  + E+ ++  E  R      AT+S         ED +S     +E K EE+K ++RK ++ K K +A + LL+  GVD D  L  A   +  A E ++Q R       S           D  D++E        E S +N   S PY       Y YQ
Sbjct:   19 GEQLSSLQNKQLQDTELLEDIRSFCKQRAAIEKEYGQ-VSHLYIDLIM--WLLCMEFCIYR-----SVYSVWRSVVEGTASIGQTRVTGAENYRNLTSEAAKTARSAKELLLKKVTYIEQLLKVQNELLETMKEVNKTKKRYVQLERVSEVAKEKAMDTEARLKKSEHSIFHSKASLQKLSAKFSTQVVECNQQLSEARNEYLLALTAANAHLNHYYQTHLPDIMTVSNLTYGDIYDRLRDYLTLISNTELNTCKFTQERFKDILVASQQVSRQQNLQLFLKDTNLFSPTLIQKFQPAGSDKMSTLESLTKGPN-VESVLDKEARRWTSRAARDYKLKTHGERVLQRLEAKR------ATVS---------EDELS----SMELKTEEVKESVRKAEVSKVKADARVELLRQVGVDVDTWLTGA---MMQANEELEQERRMSEARMSNGELSPTMDEFDFTDFEECDDNGEIFEESSLNLSGSRPYPFPCQVLYSYQ 484
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Match: Fchsd2 (FCH and double SH3 domains 2 [Source:MGI Symbol;Acc:MGI:2448475])

HSP 1 Score: 167.933 bits (424), Expect = 1.379e-42
Identity = 140/425 (32.94%), Postives = 215/425 (50.59%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ +QKL    L KR +P  +    ND   +  +  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V++++K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     T++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK I+  ++ +   E   V       LS  + +E             +E K++E + +IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:   17 IQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYL-KRDWPGIKTDDRNDYRSM--YPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRVLNELECHGV------ALSEQSRAE-------------LEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 413
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Match: Fchsd2 (FCH and double SH3 domains 2 [Source:MGI Symbol;Acc:MGI:2448475])

HSP 1 Score: 162.925 bits (411), Expect = 6.048e-41
Identity = 104/299 (34.78%), Postives = 162/299 (54.18%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGD 1069
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ +QKL    L KR +P  +    ND   +  +  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V++++K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     T++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D
Sbjct:   17 IQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYL-KRDWPGIKTDDRNDYRSM--YPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSD 307
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Match: Fchsd1 (FCH and double SH3 domains 1 [Source:MGI Symbol;Acc:MGI:2441771])

HSP 1 Score: 119.783 bits (299), Expect = 2.749e-27
Identity = 109/448 (24.33%), Postives = 201/448 (44.87%), Query Frame = 2 
Query:  188 EHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWE----IFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVT--KKLVKRLIVRE----------HKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEH-KVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSE 1480
            E    LQ +   + DL+EDIR + KQ+AA +REY Q++QKL    L +      E  +  +++   V+  WR LL+        RL  +D  + L+      R  +    ++  + L+  Q ++   V+E+ +++K+Y + ++     + KA D   ++      IF+S  +L K S KLS++   Y  +  AARNEYL  L A NAHL  Y+  +L    +++ +++ +  ++ L  +   E    ++ +++ L+  +   K   + +WE    +FL     F+     +FQ    D++     L      +A  +  +K V+R   R           H+++   ++ +    GR  P              GVE  +   +E +   +V ++K A            A L LL+++G+D  + L  A T   A  E+ ++ R SE
Sbjct:   20 EQLSILQTRQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKR------EGQRSGEADSRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG--RSAKEQVLRKGTESLQQAQAEVLQSVRELSRSRKLYGQRQRVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAARNEYLLNLVATNAHLAHYYQEELPALLKVLVSELSEYLRDPLTLLGHTE----LEAAEMILEHARHGGKATSQVNWEQDVKLFLQGPGVFSPTPPQQFQPAGADQV---CGLEWGAGGMAGESGLEKEVQRWTSRAARDYKIQHHGHRVLQRLEQRRQQAPGREAP--------------GVEQRLQEVRENIRRAQVSQVKGA------------ARLALLQEAGLDVQRWLKPAMTQ--AQDEVEQERRLSE 424
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Match: Fchsd2 (FCH and double SH3 domains 2 [Source:MGI Symbol;Acc:MGI:2448475])

HSP 1 Score: 90.8929 bits (224), Expect = 1.884e-20
Identity = 56/156 (35.90%), Postives = 88/156 (56.41%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKA 643
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ +QKL    L KR +P  +    ND   +  +  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V++++K +K Y E E+ AH +R KA
Sbjct:   15 IQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYL-KRDWPGIKTDDRNDYRSM--YPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKA 167
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Match: Srgap1 (SLIT-ROBO Rho GTPase activating protein 1 [Source:MGI Symbol;Acc:MGI:2152936])

HSP 1 Score: 66.6254 bits (161), Expect = 1.233e-10
Identity = 71/300 (23.67%), Postives = 137/300 (45.67%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADL---------LQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQ-------EMIKAQKVYSEEEKQAHEIRIKAQDAAEKVK-NKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKS-EKICRKYHWEIFLNNYP-SFNAPVQYKFQSVKGDKI 1075
            L++D++ F ++KA  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +D+         +Q   D  +  + ++    +   D +K+L  +LYT ++       E I A+    E EKQ  +   ++ D    ++  +     +S+  + K   K  ++    + +S  ARNEYL  L A NA +F Y+  DL D     D   +      L T  + E N    + +  L +I+ + + +  +   + F+  YP +F  P++++FQS  GD++
Sbjct:   45 LLQDLQDFFRKKAEIETEYSRNLEKLAERFMAKTRSTKDHQQFKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIYLNNVIMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVL-NELYTVMKTYHMYHSESISAESKLKEAEKQEEKQIGRSGDPVFHIRLEERHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNASVFKYYIHDLSDLIDCCDLGYHASLNRALRTYLSAEYNLETSRHE-GLDIIENAVDNLEPRSDKQRFMEMYPAAFCPPMKFEFQSHMGDEV 342
[Close]
BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Match: sp|Q3USJ8|FCSD2_MOUSE (F-BAR and double SH3 domains protein 2 OS=Mus musculus OX=10090 GN=Fchsd2 PE=1 SV=2)

HSP 1 Score: 167.933 bits (424), Expect = 9.649e-42
Identity = 140/425 (32.94%), Postives = 215/425 (50.59%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ +QKL    L KR +P  +    ND   +  +  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V++++K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     T++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK I+  ++ +   E   V       LS  + +E             +E K++E + +IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:   17 IQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYL-KRDWPGIKTDDRNDYRSM--YPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRVLNELECHGV------ALSEQSRAE-------------LEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 413
[Close]
BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Match: sp|O94868|FCSD2_HUMAN (F-BAR and double SH3 domains protein 2 OS=Homo sapiens OX=9606 GN=FCHSD2 PE=1 SV=3)

HSP 1 Score: 165.622 bits (418), Expect = 5.082e-41
Identity = 141/425 (33.18%), Postives = 214/425 (50.35%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDL-NVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            IQ E    LQ KH ++ DL+ED+R F ++KAA +REYAQ MQKL    L KR +P     K +D  D  +++  W+  L    + A  R+N  +  +  +S+  + +R  +    KR +DQL  +QT+L   V+++ K +K Y E E+ AH +R KA D   K K    ++F S  +L K S KL +R     +++T ARN+YL  LAA NAH   Y+  DL +  + +D +VYD  K+ L+  +  E + C   Q+     L++ S K+ R Y+ ++FL     F+ P  ++FQ    D    L       +E++L    +K   R + REHK + +++ V          +       AA SE    +L        E K++E +  IRK +I K K EA L LLK  GV  D  L  A   V
Sbjct:   17 IQVEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGMQKLASQYL-KRDWPG---VKADDRNDYRSMYPVWKSFLEGTMQVAQSRMNICENYKNFISEPARTVRSLKEQQLKRCVDQLTKIQTELQETVKDLAKGKKKYFETEQMAHAVREKA-DIEAKSK---LSLFQSRISLQKASVKLKARRSECNSKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAVQNTFQF-LLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATR-VAREHKNIVHQQRV----------LNDLECHGAAVSEQSRAEL--------EQKIDEARENIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQV 413
[Close]
BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Match: sp|X2JAU8|NWK_DROME (Protein nervous wreck OS=Drosophila melanogaster OX=7227 GN=nwk PE=1 SV=1)

HSP 1 Score: 166.392 bits (420), Expect = 1.177e-40
Identity = 125/420 (29.76%), Postives = 222/420 (52.86%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCK-ENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQK-LSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIH-LLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            +  E    LQ K+  + DL+EDIRQF  +++A ++ Y++S+ K+    L K+  P   + K E   E  N+WS WR +L + ++ A  RL   ++ Q+ ++D+ K +R  +L+  KR L  +  +Q +L+  V ++ K +K Y +EE  AH++R KA+D  EK+K K  + F S+ +L KNS +++SR +  + +S+ ARN+Y+  LAA NAH   YF VDL      ++  V++R  E L+ +   E   CS  Q+  + K+  +++++ R+Y+ +     YP     +QY F++   D +  +         TL    K L  R++     I    K++   ++ R +  ++    P              N   ++ K+EE +  IR+ + EK+K EACL  L+D G++ D+ + +A
Sbjct:   17 LHTEQVAKLQLKNQHECDLLEDIRQFTIKRSAVEKSYSESLLKISSQYLNKK-IPNIPDIKMEGMEERWNMWSVWRTVLEENEKLARARLAAIEVFQQQIADEAKVLRDYKLAIAKRSLAGIVNVQKELHLSVGDVDKTKKSYFDEEHCAHDVRDKARDIEEKLKKKKGSFFQSITSLQKNSARVTSRKELLEEKSSGARNDYVLSLAAANAHQNRYFTVDLQTTMTTMENYVFERVAEYLMLMGRTELLTCSATQNS-FGKIRDQAQQLTREYNLQCCYLFYPVLKQHIQYDFEACDNDPVRKVTAEHESAAETLTKEAKNLAGRVVKENASIRENAKKLALCQSLRDSGQRTDPNDP--------------NGPDLDTKIEEFRDQIRRSETEKTKAEACLQCLRDGGINVDEWVQEA 420
[Close]
BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Match: sp|Q86WN1|FCSD1_HUMAN (F-BAR and double SH3 domains protein 1 OS=Homo sapiens OX=9606 GN=FCHSD1 PE=1 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 3.265e-27
Identity = 115/436 (26.38%), Postives = 206/436 (47.25%), Query Frame = 2 
Query:  203 LQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWE----IFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVT--KKLVKRLI---VREHKIMGYEKEV-KSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSE 1480
            LQ     + DL+EDIR + KQ+AA +REY Q++QKL    L +          E DS    V+  WR LL+        RL  +D  + L+      R  +    ++  + L+  Q ++   V+E+ +++K+Y + E+     + KA D   ++      IF+S  +L K S KLS++   Y  +  AARNEYL  L A NAHL  Y+  +L    + + +++ +  ++ L +++  E    ++ ++V L+   + E+   +  WE    +FL     F+     +FQ    D++ +   L      +A  +  +K V+RL     R++KI  +   V +  E  R    Q A+   A                 +E +++E++ +IR+ ++ + K  A L LL+ +G+D ++ L  A T   A  E+ ++ R SE
Sbjct:   25 LQTWQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKRE----GHRSGEMDSRGRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG--RSAKEQVLRKGTENLQRAQAEVLQSVRELSRSRKLYGQRERVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTE----LEAAEVILEHAHRGEQTTSQVSWEQDLKLFLQEPGVFSPTPPQQFQPAGTDQVCV---LEWGAEGVAGKSGLEKEVQRLTSRAARDYKIQNHGHRVLQRLEQRR----QQASEREAPS---------------IEQRLQEVRESIRRAQVSQVKGAARLALLQGAGLDVERWLKPAMTQ--AQDEVEQERRLSE 426
[Close]
BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Match: sp|Q6PFY1|FCSD1_MOUSE (F-BAR and double SH3 domains protein 1 OS=Mus musculus OX=10090 GN=Fchsd1 PE=1 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 1.923e-26
Identity = 109/448 (24.33%), Postives = 201/448 (44.87%), Query Frame = 2 
Query:  188 EHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWE----IFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVT--KKLVKRLIVRE----------HKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEH-KVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSE 1480
            E    LQ +   + DL+EDIR + KQ+AA +REY Q++QKL    L +      E  +  +++   V+  WR LL+        RL  +D  + L+      R  +    ++  + L+  Q ++   V+E+ +++K+Y + ++     + KA D   ++      IF+S  +L K S KLS++   Y  +  AARNEYL  L A NAHL  Y+  +L    +++ +++ +  ++ L  +   E    ++ +++ L+  +   K   + +WE    +FL     F+     +FQ    D++     L      +A  +  +K V+R   R           H+++   ++ +    GR  P              GVE  +   +E +   +V ++K A            A L LL+++G+D  + L  A T   A  E+ ++ R SE
Sbjct:   20 EQLSILQTRQQREADLLEDIRSYSKQRAAIEREYGQALQKLAGPFLKR------EGQRSGEADSRTVFGAWRCLLDATVAGGQTRLQASDRYRDLAGGTG--RSAKEQVLRKGTESLQQAQAEVLQSVRELSRSRKLYGQRQRVWALAQEKAADVQARLNRSDHGIFHSRTSLQKLSTKLSAQSAQYSQQLRAARNEYLLNLVATNAHLAHYYQEELPALLKVLVSELSEYLRDPLTLLGHTE----LEAAEMILEHARHGGKATSQVNWEQDVKLFLQGPGVFSPTPPQQFQPAGADQV---CGLEWGAGGMAGESGLEKEVQRWTSRAARDYKIQHHGHRVLQRLEQRRQQAPGREAP--------------GVEQRLQEVRENIRRAQVSQVKGA------------ARLALLQEAGLDVQRWLKPAMTQ--AQDEVEQERRLSE 424
[Close]
BLAST of FCH and double SH3 domains protein vs. TrEMBL
Match: A0A419PNJ8 (F-BAR and double SH3 domains protein 2 OS=Clonorchis sinensis OX=79923 GN=FCHSD2 PE=4 SV=1)

HSP 1 Score: 352.829 bits (904), Expect = 4.089e-102
Identity = 179/413 (43.34%), Postives = 266/413 (64.41%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKIL 1417
            I NEHF  L  K  S+TDL++DIR FCKQ+AA +REY QS++KL    L K+      +   +     ++W  WR LL++    A   L  ++  Q++   LKP+++ R++  KR+ +QL+ LQ DL  CVQEM+K+ KVY+EEEKQA E R+KA    EK++ +ST+IF+SMA LH+N  KL  R  AY  RS  ARNEYLFQLAAINAHL  YF  D+    + +D +++++  E+L T++  E        + + ++ + + +I R Y WE FL   P F+  VQY+F+ ++GD+I LL   + KE +L  + +KL +RL++RE +I  YE E+K+ +TG   P  ++   P +      E+L+S+NQEYVEHKVEE++FAIR+E+IE+ KIEACLGLL++S V+  + +
Sbjct:   71 IHNEHFTKLHNKSTSETDLLDDIRLFCKQRAAIEREYGQSLRKLTNGFLTKKELSNAISMDHDIPNGQSIWRVWRALLDESNNLALSHLRASETQQRICRDLKPLKLQRIAVGKRVFEQLRTLQGDLAACVQEMVKSHKVYAEEEKQAQETRLKAMATEEKIRRRSTDIFHSMAQLHRNYEKLIIRRQAYDARSATARNEYLFQLAAINAHLKHYFTKDVPSLVKTLDGELFEKLSEVLSTLSQHEAEMCALTRERFQRVFRDASQITRSYAWESFLRACPLFDKAVQYQFEPMEGDEITLLRSPDAKEASLEQIARKLARRLVLRERRIASYENELKTLQTGSANPHNNSQAVPGSPDSENQEELLSFNQEYVEHKVEEIQFAIRREEIERVKIEACLGLLRNSAVEVKQFV 483

HSP 2 Score: 74.7146 bits (182), Expect = 8.807e-10
Identity = 46/140 (32.86%), Postives = 75/140 (53.57%), Query Frame = 2 
Query: 1619 QPGSACSTPNKPQSYASTVTKSSDSRESIN-------------------HEIISTKADINNEEKV--SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKV 1975
            +PG+   TPN+  ++ S    +S S +  N                   H  +  +   +N+  V  S+D E  W   G   +A  + EF+A   + +ELDLV++E V+LL+ + + GW+KVRSLIDG EG+VP++YL++
Sbjct:  602 KPGNGTVTPNRTTAWGSLRAINSASHDYQNVEPTPRAHDDLSMDKTRTQHGSLGRREHKSNDALVNESLDLELLWSDHGRLQQASVLHEFRAK--RPDELDLVMHETVVLLDPAGSSGWVKVRSLIDGNEGLVPLNYLRL 739
[Close]
BLAST of FCH and double SH3 domains protein vs. TrEMBL
Match: A0A075ADU2 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_06472 PE=4 SV=1)

HSP 1 Score: 352.443 bits (903), Expect = 9.379e-102
Identity = 179/413 (43.34%), Postives = 266/413 (64.41%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKIL 1417
            I NEHF  L  K  S+TDL++DIR FCKQ+AA +REY QS++KL    L K+      +   +     ++W  WR LL++    A   L  ++  Q++   LKP+++ R++  KR+ +QL+ LQ DL  CVQEM+K+ KVY+EEEKQA E R+KA    EK++ +ST+IF+SMA LH+N  KL  R  AY  RS  ARNEYLFQLAAINAHL  YF  D+    + +D +++++  E+L T++  E        + + ++ + + +I R Y WE FL   P F+  VQY+F+ ++GD+I LL   + KE +L  + +KL +RL++RE +I  YE E+K+ +TG   P  ++   P +      E+L+S+NQEYVEHKVEE++FAIR+E+IE+ KIEACLGLL++S V+  + +
Sbjct:   61 IHNEHFTKLHNKSTSETDLLDDIRLFCKQRAAIEREYGQSLRKLTNGFLTKKELSNAISLDHDIPNGQSIWRVWRALLDESNNLALSHLRASETQQRICRDLKPLKLQRIAVGKRVFEQLRTLQGDLAACVQEMVKSHKVYAEEEKQAQETRLKAMAMEEKIRRRSTDIFHSMAQLHRNYEKLIIRRQAYDARSATARNEYLFQLAAINAHLRHYFTKDVPSLVKTLDGELFEKLSEVLSTLSQHEAEMCALTRERFQRVFRDASQITRSYAWESFLRACPLFDKAVQYQFEPMEGDEITLLRSPDAKEASLEQIARKLARRLVLRERRIASYENELKTLQTGSANPHNNSQAVPGSPDSENQEELLSFNQEYVEHKVEEIQFAIRREEIERVKIEACLGLLRNSAVEVKQFV 473

HSP 2 Score: 74.7146 bits (182), Expect = 9.983e-10
Identity = 46/140 (32.86%), Postives = 75/140 (53.57%), Query Frame = 2 
Query: 1619 QPGSACSTPNKPQSYASTVTKSSDSRESIN-------------------HEIISTKADINNEEKV--SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKV 1975
            +PG+   TPN+  ++ S    +S S +  N                   H  +  +   +N+  V  S+D E  W   G   +A  + EF+A   + +ELDLV++E V+LL+ + + GW+KVRSLIDG EG+VP++YL++
Sbjct:  619 KPGNGTVTPNRTTAWGSLRAINSASHDYQNVEPTLRAHDDLSMDKTRTQHGSLGRREHKSNDALVNESLDLELLWSDHGRLQQASVLHEFRAK--RPDELDLVMHETVVLLDPAGSSGWVKVRSLIDGNEGLVPLNYLRL 756
[Close]
BLAST of FCH and double SH3 domains protein vs. TrEMBL
Match: A0A095CDA4 (FCH and double SH3 domains protein 2 OS=Schistosoma haematobium OX=6185 GN=MS3_09113 PE=4 SV=1)

HSP 1 Score: 350.132 bits (897), Expect = 9.719e-101
Identity = 195/432 (45.14%), Postives = 282/432 (65.28%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKEN-CKENDS----EDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLS---------PAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDAR 1429
            I NEH+  LQ KH S+T+L++D+R +CKQ+A+ +REY QS+QKL+ +LL+K+ F  + +   +ND+    +  NVW  W  LL +    A   L  +D  Q+LS +LKP++  RLS NKR+ +QLK+LQ DL  CVQEM+K+ KVY+EEEKQA E R+K   A EK++ +ST+IF+SMA LH+N +KL  +  A+ +RST ARNEYLFQL AINAHL  YF  DL   A+ +D ++Y++  E+  T+  +E + C++ Q + +  L K+S +I R   WE FL   P FN PVQY+F+ +KGD+   L      E+ L  + +KL +RL++RE  I  YE E+K  + G VTP+ S             P         +L+++NQEYVE+KVEEL+FAIR+EKIE+ KIEACL LL++S +D ++ + +AR
Sbjct:   42 IHNEHYAKLQSKHASETELLDDMRMYCKQRASIEREYGQSLQKLVNSLLSKKEFTTQSSYSSDNDTILPNKQHNVWHIWYSLLAESNNLALSHLRASDNQQRLSTELKPLKSQRLSVNKRVFEQLKILQGDLAACVQEMVKSHKVYAEEEKQAQETRLKTLAAKEKIQRRSTDIFHSMAQLHRNYDKLLGKRQAFDSRSTTARNEYLFQLTAINAHLKHYFSEDLPVLAKTLDGELYEKLGEVFTTLCENEIEFCTITQKR-FDNLFKESSQINRTKAWEDFLKLSPLFNKPVQYQFEPIKGDETTKLCSAT-NESNLEQIARKLSRRLVIRERCIKSYENEMKMLQAGYVTPVSSMMTGSNNQIQQQQPTNSETENNNELLAFNQEYVENKVEELQFAIRREKIEQVKIEACLSLLRNSSIDINEFISEAR 471

HSP 2 Score: 96.6709 bits (239), Expect = 1.633e-16
Identity = 79/262 (30.15%), Postives = 116/262 (44.27%), Query Frame = 2 
Query: 1760 IDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIP--------------QSVTXXXXXXXXXXXXXIAD-------------------YVNVLP---------ISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISR----------------------VSQDGVDDGWWEGYKVIW-----NEEKNCWVILQRGFFPSMVVR 2338
            ID E  W  +    RA  + EF+A      ELDLVV+E V+LLN    +GWIKVRSLIDG EG+VP+SYLK+    +P              QS++    + N   +  + +                   +V++ P           +V S EL   +   + GS  V++   F  TN DEL  +   +I++I R                      +S   +DDGWWEG  ++      NE++  + I  RG FPSM+V+
Sbjct:  700 IDFEAIWSENNRLRRATVVHEFRAKKSN--ELDLVVHETVVLLNNEPQNGWIKVRSLIDGNEGLVPISYLKLSNIDVPKHNSKIIMNGDNSNQSISTLNTSGNDILHSKLTNCSEDIDQKNSKKPNQVDPTFVSLPPEIDPPRLLCSDEVSSHEL---SKPPLSGS-FVRSLIDFRGTNPDELSFKAGAVIRVIGRAPNINDLVNNSSTATRRDQLTSISGYSIDDGWWEGDLLVAESNKNNEDQQFYSI--RGVFPSMLVQ 953
[Close]
BLAST of FCH and double SH3 domains protein vs. TrEMBL
Match: A0A430QJL9 (F-BAR and double SH3 domains protein OS=Schistosoma bovis OX=6184 GN=DC041_0008688 PE=4 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 2.463e-100
Identity = 194/432 (44.91%), Postives = 281/432 (65.05%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKEN-CKENDS----EDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADE-QNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLS---------PAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDAR 1429
            I NEH+  LQ KH S+T+L++D+R +CKQ+A+ +REY QS+QKL+ + L+K+ F  + +   +ND+    +  NVW  W  LL +    A   L  +D  Q+LS +LKP++  RLS NKR+ +QLK+LQ DL  CVQEM+K+ KVY+EEEKQA E R+K   A EK++ +ST+IF+SMA LH+N +KL  +  A+ +RST ARNEYLFQL AINAHL  YF  DL   A+ +D ++Y++  E+  T+  +E + C++ Q + +  L K+S +I R   WE FL   P FN PVQY+F+ +KGD+   L      E+ L  + +KL +RL++RE  I  YE E+K  + G VTP+ S             P         +L+++NQEYVE+KVEEL+FAIR+EKIE+ KIEACL LL++S +D ++ + +AR
Sbjct:   42 IHNEHYAKLQSKHASETELLDDMRMYCKQRASIEREYGQSLQKLVNSFLSKKEFTTQSSYSSDNDTILPNKQHNVWHIWYSLLAESNNLALSHLRASDNQQRLSTELKPLKSQRLSVNKRVFEQLKILQGDLAACVQEMVKSHKVYAEEEKQAQETRLKTLAAKEKIQRRSTDIFHSMAQLHRNYDKLLGKRQAFDSRSTTARNEYLFQLTAINAHLKHYFSEDLPVLAKTLDGELYEKLGEVFTTLCENEIEFCTITQKR-FDNLFKESSQINRTNAWEDFLKLSPLFNKPVQYQFEPIKGDETTKLCSAT-NESNLEQIARKLSRRLVIRERCIKSYENEMKMLQAGYVTPVSSMMTGSNNQIQQQQPTNSETENNNELLAFNQEYVENKVEELQFAIRREKIEQVKIEACLSLLRNSSIDINEFISEAR 471

HSP 2 Score: 95.9005 bits (237), Expect = 2.918e-16
Identity = 96/341 (28.15%), Postives = 148/341 (43.40%), Query Frame = 2 
Query: 1550 ELSQINNEESFPYSLSKYSGYEYQPGSACS--TPNKPQSYASTVTKSSDSRESINHEIISTKADI-----NN--EEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIP--------------QSVTXXXXXXXXXXXXXIAD-------------------YVNVLP---------ISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISR----------------------VSQDGVDDGWWEGYKVIWNEEKN-----CWVILQRGFFPSMVVR 2338
            +L+ +N  + FP +      ++YQ  S  S  T +    + ST+    +S +S  +  +++ + I     NN    K  ID E  W  +    RA  + EF+A      ELDLVV+E V+LLN    +GWIKVRSLIDG EG+VP+SYLK+    +P              QS++    + N   +  + +                   +V++ P           +V S EL   +   + GS  V++   F  TN DEL  +   +I++I R                      +S   +DDGWWEG  ++    KN      + I  RG FPSM+V+
Sbjct:  621 KLNCLNQNDLFPNNNETRVKHDYQNVSQISSRTHDDITVHRSTINNDKNSNKSHPNGTLNSFSSIRIGSSNNLTNNKDDIDFEAIWSENNRLRRATVVHEFRAKKSN--ELDLVVHETVVLLNNEPQNGWIKVRSLIDGNEGLVPISYLKLSNIDVPKHNSKIIMNGDNSNQSISTLNTSGNDILHSKLTNCSEDIDQKNSKKPNQVDPTFVSLPPEIDPPRLLCADEVSSHEL---SKPPLSGS-FVRSLIDFRGTNPDELSFKAGAVIRVIGRAPNINDLVNNSSTATRRDQLTSISGYSIDDGWWEGDLLVAESNKNDEDQQFYSI--RGVFPSMLVQ 953
[Close]
BLAST of FCH and double SH3 domains protein vs. TrEMBL
Match: A0A087W252 (Fch and double sh3 domains protein 2 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000257850 PE=4 SV=1)

HSP 1 Score: 342.043 bits (876), Expect = 3.399e-99
Identity = 189/427 (44.26%), Postives = 270/427 (63.23%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLS-----------PAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDA 1426
            IQ+EHF  L  K  ++T+L+ED+R FCKQ+A  D+EY Q++QKL  + L+K+ F A  N    ++   +VW  W+  L ++   A   L  A++  +LS +LKP++  R++ +KRI +QLK LQ DL   +QEM+K+QK+YSEEEKQAHE R+KA +  +K++ +STN+F++MA LH+N  K+S R D Y+ RS  ARNEYLFQL AINAHL  Y   D+ D AQI+D DVYDRF+E+L   +  E          +  L+++S KI RK  WE F+   P F+A V++ F+   GD I  L+ +N KE +   V KKL +R + RE +I  Y +E+    +GR++P    ++S           P  D +   ED  + NQEYVE+KVEEL+FAIR+E+IEK+KI ACL LLK + VD    L +A
Sbjct:   13 IQSEHFSRLLSKQNNETELLEDMRSFCKQRAILDKEYGQALQKLCSSFLSKKEFLALPNPP--NTGHRSVWDIWKLFLQEFNALALSHLKLAEVHHRLSLELKPVKSLRVAVSKRIFEQLKSLQNDLAASMQEMVKSQKIYSEEEKQAHETRLKAMNIEDKLRRRSTNLFSTMAQLHRNHAKISQRRDEYENRSAGARNEYLFQLTAINAHLDHYLKTDIPDLAQILDGDVYDRFREVLSKTSEMELEICRHHQDPFKALLEESSKINRKTAWENFIKELPIFSADVEFHFEPRDGDTISSLLSVNAKEGSFEQVAKKLARRFVTRERRIKSYRQEINDLCSGRISPSPGMSVSLSQVPSPPRKFPLKDCDTS-EDSGALNQEYVENKVEELEFAIRREEIEKTKISACLELLKKTHVDVQAALYEA 436

HSP 2 Score: 88.9669 bits (219), Expect = 3.336e-14
Identity = 61/212 (28.77%), Postives = 98/212 (46.23%), Query Frame = 2 
Query: 1769 EEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKV--IYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSN--TNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADLSPICPR 2392
            E DW G G   +A A++EF A+  + +E+++V NE V+LL   + + W+KVRSL+DG+ G+VP ++L +       P            D  +  +D   + P S       L +    + + G   V+    F+ T  DEL      +I ++ + +   VDDGW EG  V   + +        G FPSM+V       + +  LS   PR
Sbjct:  570 EVDWTGGGQLPKATAMYEFLAA--RSDEINMVCNERVVLLGTGDGEDWVKVRSLLDGKAGLVPRAFLSIDPTPPPAPPHPAVPALAAKSDTEQEPSDKTPLSPTSSPSEPVALPHLPVEQCLAG-QFVRALIDFAGTAEDELSFGVGAVIHVLGQPAAGEVDDGWIEGELVPLTDAETT-TPPACGVFPSMLVETVTPEDIWQRRLSASRPR 777
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Match: si:ch211-176g13.8 (si:ch211-176g13.8 [Source:ZFIN;Acc:ZDB-GENE-091204-303])

HSP 1 Score: 146.362 bits (368), Expect = 1.349e-35
Identity = 126/422 (29.86%), Postives = 210/422 (49.76%), Query Frame = 2 
Query:  182 QNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLV--PLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
            Q E    L  KH +D DL+ED+R + ++KA  +++YAQ++QKL    L KR +P  ++ ++ D    NV + W+  L    +    R++  D  + ++S+ +K  R+ +    K+ ++QL  +Q +L   V+++ K++K Y E E+ A  +R KA D   K K    ++F S ++L + S KL ++ +   +++T ARN+YL  LAA NAH   ++  DL    +I+D  VYD  K  LV++   E   S      +  L++KS  + + +H E+F+   P       ++FQ  + D +  L       +E++L    +K   R + REHK + + +   S   G   P Q                    N   +E K+EE K +IRK +  K K EA L LL+D GV  D  +  A   V
Sbjct:   18 QAEQLSRLNVKHQTDCDLLEDLRTYSQKKAVIEKDYAQALQKLASQYL-KRDWPGVQSEEQKDYR--NVCTVWKAYLEGVVKVTQSRISGCDSYRNQVSEPIKTFRVQKEQQLKKSIEQLTRIQAELQDTVKDLTKSRKKYQEAEQMAQAVREKA-DMEAKSK---LSLFQSRSSLKRASVKLKAKKNECNSKATHARNDYLLTLAAANAHQGRHYETDLISCIKILDGSVYDHMKGYLVSLCQVELEASHTVQDTFNFLLEKSTGVIQDFHQELFIQENPVLQKGSLFQFQPCENDSVIQLQKETGTAEEHSLNKEARKWATR-VAREHKNIIHNQRTLSDCEG---PPQQ-----------------EQNSSELELKMEEAKESIRKAETVKLKAEARLNLLRDVGVAVDTWMKSAMNQV 411
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Match: ENSAMXT00000014010.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000117.1:1191655:1331390:1 gene:ENSAMXG00000013591.2 transcript:ENSAMXT00000014010.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 141.354 bits (355), Expect = 3.762e-34
Identity = 104/339 (30.68%), Postives = 177/339 (52.21%), Query Frame = 2 
Query:  182 QNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPA-KENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVP--LNLKENTLANVTKKLVKRLIVREHK-IMGYEK 1183
              E    L  KH ++ DL+ED+R + ++KAA +R+YAQ++QKL  N   KR +P  K + +  D    NV+  WR  L    +    RL  ++  + ++SD  K +R+ +    K+ ++QL  +Q +L   V+++ K++K Y E E+ A  +R KA D   K K     +F S  +L K S KL ++     +++T ARNEYL  LAA NAH   Y+  DL +  + +D +VYD  K+ L++    E          +  L++KS ++ + ++ ++FL   P F+    ++FQ    D    L       +E++L    ++   R + REHK I+ Y++
Sbjct:   23 HTEQLTRLHLKHQTECDLLEDMRTYSQKKAALERDYAQALQKLA-NQYLKRDWPGIKPDDQRTDYR--NVYGVWRAYLEGTVQVTQSRLFVSENYKNEISDPAKTVRLYKEQQLKKCIEQLGRIQAELQDSVKDLAKSKKKYFELEQIAQAVREKA-DIEAKSK---LGLFQSRISLQKASVKLKAKRSDCNSKATHARNEYLLTLAAANAHHDRYYQTDLANCIKALDGNVYDHVKDYLMSFCRTELEAVQAVHNTFQFLLEKSSRVVQDFNQQLFLQENPVFHKAQDFQFQPCDSDASRQLESETGTTEEHSLNKEARRWATR-VAREHKNIIHYKR 353
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Match: srgap1b (SLIT-ROBO Rho GTPase activating protein 1b [Source:ZFIN;Acc:ZDB-GENE-041210-103])

HSP 1 Score: 70.0922 bits (170), Expect = 9.903e-12
Identity = 72/304 (23.68%), Postives = 131/304 (43.09%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLST-NKRILDQLK----LLQTDLYTCVQEMIKAQKVYS--EEEKQAHEIRIKAQDAAEKVKNKSTNIF-----------NSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPS-FNAPVQYKFQSVKGDKIHLLV 1087
            L++D++ F ++K+  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +DL   L++ +   RI+ +S  N R+L + K     LQ DL   + E+    K Y     E  + E ++K  +   + + +   +F           N+   + K   K  ++    + +   ARNEYL  L A NA LF Y+  DL       D   +      L T  + E +    + +    L    E +  +   + F+  +P+ F  P ++ FQS  GD++  L 
Sbjct:   35 LLQDLQDFFRKKSEIESEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDLY--LNNVI--TRISHVSEDNTRLLKKSKEITFQLQEDLMKILNELYTVMKTYHMYHTETLSAETKLKEAERQGERQGRGGEVFGLRNEERHQRRNAARKIQKMKEKRQAKYSENKLKVMKARNEYLLTLEAANAALFKYYIQDLSHLIDCCDLGYHASLSRALRTYLSAEYSLETSRHEGLDILEGAVESLDPRSDRQRFMETHPTAFTPPARFTFQSHMGDQVSQLT 334
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Match: srgap1a (SLIT-ROBO Rho GTPase activating protein 1 [Source:NCBI gene;Acc:103045357])

HSP 1 Score: 64.6994 bits (156), Expect = 3.921e-10
Identity = 72/303 (23.76%), Postives = 138/303 (45.54%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNK-RILDQLK----LLQTDLYTCVQEMIKAQKVYS--EEEKQAHEIRIKAQDAAE--KVKNKSTNIFN-----------SMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKS-EKICRKYHWEIFLNNYPS-FNAPVQYKFQSVKGDKI 1075
            L++D++ F ++K+  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +D+   L++ +  +R  ++S +  R+L + K     LQ DL   + E+    K Y     E  + E ++K  +  E  ++      +F+           S+  + K   K  ++    + +S  ARNEYL  L A N+ +F Y+  DL D     D   +      L T  + E N    + +  L +I+ + + +  +   + F+  YP+ F  PV++ FQS  GD++
Sbjct:   46 LLQDLQDFFRKKSEIEMEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIY--LNNVI--MRFMQISEDSTRLLKKSKEIAFQLQEDLMKVLNELYTVMKTYHMYHTESISAESKLKEFEKQEERQIGRSGEPVFSMRMEEKHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNSSVFKYYIHDLPDLIDCCDLGYHFSLNRALRTYLSAEYNLETSRHE-GLDIIENAVDSLDPRSDRQRFMEMYPTAFCPPVKFDFQSHMGDEV 343
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Match: srgap1a (SLIT-ROBO Rho GTPase activating protein 1 [Source:NCBI gene;Acc:103045357])

HSP 1 Score: 64.6994 bits (156), Expect = 4.395e-10
Identity = 72/303 (23.76%), Postives = 138/303 (45.54%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNK-RILDQLK----LLQTDLYTCVQEMIKAQKVYS--EEEKQAHEIRIKAQDAAE--KVKNKSTNIFN-----------SMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKS-EKICRKYHWEIFLNNYPS-FNAPVQYKFQSVKGDKI 1075
            L++D++ F ++K+  + EY+++++KL    +AK          + D   L+  + W  LLNQ +  +      +D+   L++ +  +R  ++S +  R+L + K     LQ DL   + E+    K Y     E  + E ++K  +  E  ++      +F+           S+  + K   K  ++    + +S  ARNEYL  L A N+ +F Y+  DL D     D   +      L T  + E N    + +  L +I+ + + +  +   + F+  YP+ F  PV++ FQS  GD++
Sbjct:   16 LLQDLQDFFRKKSEIEMEYSRNLEKLAERFMAKTRSTKDHQQYKKDQNLLSPVNCWYLLLNQVRRESKDHATLSDIY--LNNVI--MRFMQISEDSTRLLKKSKEIAFQLQEDLMKVLNELYTVMKTYHMYHTESISAESKLKEFEKQEERQIGRSGEPVFSMRMEEKHQRRSSVKKIEKMKEKRQAKYSENKLKSIKARNEYLLTLEATNSSVFKYYIHDLPDLIDCCDLGYHFSLNRALRTYLSAEYNLETSRHE-GLDIIENAVDSLDPRSDRQRFMEMYPTAFCPPVKFDFQSHMGDEV 313
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Nematostella
Match: EDO38999 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBA8])

HSP 1 Score: 173.711 bits (439), Expect = 1.308e-44
Identity = 132/424 (31.13%), Postives = 218/424 (51.42%), Query Frame = 2 
Query:  179 IQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKE-NCKENDSEDLNVWSTWRDLLNQYQESANLRLNTAD-LLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLA--NVTKKLVKRLIVREHKIMGYEKEVKSFET--GRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDART 1432
            IQ E  + LQ+K   + DL+EDIR + KQ++A ++EY+Q++QKL    + KR F A E    E     L+VW T   +L++       RL  A+ LL +++D +K  + N+    K+  + L+ +  +++T V+EM K++K Y E EK AH  R +A +A +K K K+   F S + L KN +K S+R +  + RST ARNEYL  LAA NAH   Y+  DL +    +  D YD+ +E    I+      S  + + +  +  ++  I + +  E FL++       + Y++   +GDKI+ ++ ++ K + LA     +KL  RL   +  I   +K + S  +  G +T   + T  P+AD         +  +E    +V +LK             EACL LLK +GV+ D+ +  A +
Sbjct:   65 IQTEQTLKLQQKFQFEQDLLEDIRVYAKQRSAIEKEYSQALQKLDSQFIQKREFSADEITGNERYRTPLSVWKT---VLDESASVGKHRLEMAEALLTQVADSIKAFKTNKAQIFKKNQELLQKIHEEIFTTVREMSKSKKGYMEMEKLAHVAREQAAEAEDKYKKKNVKFFQSKSTLEKNVSKSSNRKETSERRSTMARNEYLLCLAASNAHAMRYYCTDLQEIMNSVYGDFYDKVREYFSIISNLGVEASTSEHKGYAHVGSEASMIDKNFCVETFLSHNKVLTEVLHYEYDPYRGDKINTILTID-KSSGLALNKEARKLALRLAREQKNIRDKQKALSSMNSSQGDLTDGPTDTDQPSAD---------ALREEIRHSEVIKLK------------AEACLELLKQAGVNVDEWIKSANS 463
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Nematostella
Match: EDO46865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNI7])

HSP 1 Score: 52.373 bits (124), Expect = 7.336e-7
Identity = 54/241 (22.41%), Postives = 113/241 (46.89%), Query Frame = 2 
Query:  233 LIEDIRQFCKQKAAADREYAQSMQKLILNLLAK-RHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTAD-LLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTR-------STAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCS 928
             + D++++CK+ +  + EY++++ +L    L + + F A+   K + + D+     W  LL + +  A  R + +D L   ++++   +  +    +K+  +   +LQ +L   V E+ +  + Y       H +  +++ A  K+K+    +  S  +  KN  K++ + + +Q R       S  A+NEY+  L + N+ L  Y+   LGD     D + +D F+  +   T  E N S
Sbjct:   30 FLADLQEYCKKMSEVETEYSKNLDRLSDRFLDRLQKFKAQRCFKRSTTMDV-----WHKLLVETKNRAKQRQSFSDNLANNIANRFMSMSDDYQRISKKCREAGLILQDELCKTVHELQRKLRKY-------HTMFGESKTAESKLKSTEIALSKSEESGRKNE-KMTKQKEKHQQRYSENKRKSVKAKNEYVLALKSTNSFLQYYYTNCLGDLVDGFDFNFHDSFERAIAAYTQAETNAS 257
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Match: ENSORLT00000042060.1 (FCH and double SH3 domains 2 [Source:NCBI gene;Acc:101161820])

HSP 1 Score: 154.451 bits (389), Expect = 3.150e-38
Identity = 127/423 (30.02%), Postives = 213/423 (50.35%), Query Frame = 2 
Query:  182 QNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLN--LKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
              E    L  KH ++ DL+ED+R +  +K   +R+YAQ++QKL    L KR +P   +  +  ++  NV++ WR  L    + +  +LN  D  + ++S+  K +R+ +    K+ +DQL  +Q +L   V+E+ KA+K Y E E+ AH +R KA D   K K     +F S  +L K S KL ++     +++T ARN+YL  LAA NAH   Y+H DL    Q +D  +Y+  K+ LV +   E   S      +  L++KS +I ++++ ++F+   P F+    ++FQ  + D    L   +   +E++L    +K   R + REHK I+ +++ ++  E+  + P +   L                    +E K+E+ K  +RK +  K K EA L LL+  GV  D  L  A   V
Sbjct:   18 HTEQMTRLHFKHQTECDLLEDMRSYSLKKGQLERDYAQALQKLASQYL-KRDWPGI-SPDDQRTDYRNVYAVWRAYLEGTVQVSQSKLNVCDNYKSQVSEPAKTVRLYKEQQLKKTIDQLSDIQAELQESVKELAKAKKKYYECEQVAHAVREKA-DIEAKSK---LGLFQSRISLQKASVKLKAKRSDCNSKATQARNDYLLTLAAANAHHDRYYHTDLPHCIQALDGRIYEHVKDYLVALCRTELEASQTSHNTFQFLLEKSTRIIQEFNQQLFMQENPVFHKSQDFQFQPSECDMSRQLESESGTTEEHSLNKEARKWATR-VAREHKNIIHFKRSLEECESHGLPPTEQGRLE-------------------LELKIEDTKEMMRKAETIKLKAEARLDLLRQVGVAVDTWLKSAMNQV 414
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Match: ENSORLT00000012890.3 (FCH and double SH3 domains 2 [Source:NCBI gene;Acc:101161820])

HSP 1 Score: 149.828 bits (377), Expect = 6.316e-37
Identity = 127/423 (30.02%), Postives = 212/423 (50.12%), Query Frame = 2 
Query:  182 QNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLN--LKENTLANVTKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
              E    L  KH ++ DL+ED+R +  +K   +R+YAQ++QKL    L KR +P   +  +  ++  NV++ WR  L    + +  +LN  D  + ++S+  K +R+ +    K+ +DQL  +Q +L   V+E+ KA+K Y E E+ AH +R KA D   K K     +F S  +L K S KL ++     +++T ARN+YL  LAA NAH   Y+H DL    Q +D  +Y+  K+ LV +   E   S      +  L++KS ++  K++ ++F+   P F+    ++FQ  + D    L   +   +E++L    +K   R + REHK I+ +++ ++  E+  + P +   L                    +E K+E+ K  +RK +  K K EA L LL+  GV  D  L  A   V
Sbjct:   19 HTEQMTRLHFKHQTECDLLEDMRSYSLKKGQLERDYAQALQKLASQYL-KRDWPGI-SPDDQRTDYRNVYAVWRAYLEGTVQVSQSKLNVCDNYKSQVSEPAKTVRLYKEQQLKKTIDQLSDIQAELQESVKELAKAKKKYYECEQVAHAVREKA-DIEAKSK---LGLFQSRISLQKASVKLKAKRSDCNSKATQARNDYLLTLAAANAHHDRYYHTDLPHCIQALDGRIYEHVKDYLVALCRTELEASQTSHNTFQFLLEKSTRV--KFNQQLFMQENPVFHKSQDFQFQPSECDMSRQLESESGTTEEHSLNKEARKWATR-VAREHKNIIHFKRSLEECESHGLPPTEQGRLE-------------------LELKIEDTKEMMRKAETIKLKAEARLDLLRQVGVAVDTWLKSAMNQV 413
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Match: ENSORLT00000044556.1 (FCH and double SH3 domains 2 [Source:NCBI gene;Acc:101161820])

HSP 1 Score: 144.05 bits (362), Expect = 6.790e-35
Identity = 130/447 (29.08%), Postives = 214/447 (47.87%), Query Frame = 2 
Query:  185 NEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKI----HLLV-----PLNLKENTLANV------------------TKKLVKRLIVREHK-IMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTV 1438
             E    L  KH ++ DL+ED+R +  +K   +R+YAQ++QKL    L KR +P   +  +  ++  NV++ WR  L    + +  +LN  D  + ++S+  K +R+ +    K+ +DQL  +Q +L   V+E+ KA+K Y E E+ AH +R KA D   K K     +F S  +L K S KL ++     +++T ARN+YL  LAA NAH   Y+H DL    Q +D  +Y+  K+ LV +   E   S      +  L++KS +I ++++ ++F+   P F+    ++FQ  + D        LV     P++    TLA                     +K   R + REHK I+ +++ ++  E+  + P +   L                    +E K+E+ K  +RK +  K K EA L LL+  GV  D  L  A   V
Sbjct:   19 TEQMTRLHFKHQTECDLLEDMRSYSLKKGQLERDYAQALQKLASQYL-KRDWPGI-SPDDQRTDYRNVYAVWRAYLEGTVQVSQSKLNVCDNYKSQVSEPAKTVRLYKEQQLKKTIDQLSDIQAELQESVKELAKAKKKYYECEQVAHAVREKA-DIEAKSK---LGLFQSRISLQKASVKLKAKRSDCNSKATQARNDYLLTLAAANAHHDRYYHTDLPHCIQALDGRIYEHVKDYLVALCRTELEASQTSHNTFQFLLEKSTRIIQEFNQQLFMQENPVFHKSQDFQFQPSECDMTLSSEEQLVDIEPSPVSAMRMTLAQSRQLESESGTTEEHSLNKEARKWATR-VAREHKNIIHFKRSLEECESHGLPPTEQGRLE-------------------LELKIEDTKEMMRKAETIKLKAEARLDLLRQVGVAVDTWLKSAMNQV 439
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Match: si:ch211-176g13.8 (F-BAR and double SH3 domains protein 2 [Source:NCBI gene;Acc:101168430])

HSP 1 Score: 137.117 bits (344), Expect = 1.072e-32
Identity = 84/301 (27.91%), Postives = 159/301 (52.82%), Query Frame = 2 
Query:  176 QIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKI 1075
            QI  E    LQ  H +  DL+ED+R F  ++ A +++YAQ++QKL  N   KR +P  E  +E D    N++  W+  L    ++   R+++ +  + +++D  K  R+ +    ++ ++QL ++Q +L   V+E+ K++K Y E E  A  +R    D AE       ++F S ++L + + KL ++ +   +++T ARN+YL  LAA NAH   Y+  DL D  +++D  +Y++ K+ LV++   E          + +L+  S ++ +++H + F+     F     + +Q V  D +
Sbjct:   86 QIHGEQMSQLQINHQTQCDLLEDLRTFSLKRVAVEKDYAQALQKLA-NQYLKRDWPDSEKDEEPDHR--NMYWVWKAYLEATVQATQSRISSCENYKVQVADPAKTARLQKEQQLRKCIEQLTVVQAELQESVKELTKSRKKYQEAELMAQAVR----DKAELEAKSRLSLFQSKSSLQRATVKLKAKRNECSSKATHARNDYLLTLAAANAHQRRYYTTDLMDCIKVLDGRIYEQVKDYLVSLCQTELETYQAVHDTFNQLLNSSTRVAQEFHQQFFVQKNLLFQQSPDFSYQPVDSDTV 379
[Close]
BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Match: si:ch211-176g13.8 (F-BAR and double SH3 domains protein 2 [Source:NCBI gene;Acc:101168430])

HSP 1 Score: 137.117 bits (344), Expect = 1.379e-32
Identity = 84/301 (27.91%), Postives = 159/301 (52.82%), Query Frame = 2 
Query:  176 QIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQ-KLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKI 1075
            QI  E    LQ  H +  DL+ED+R F  ++ A +++YAQ++QKL  N   KR +P  E  +E D    N++  W+  L    ++   R+++ +  + +++D  K  R+ +    ++ ++QL ++Q +L   V+E+ K++K Y E E  A  +R    D AE       ++F S ++L + + KL ++ +   +++T ARN+YL  LAA NAH   Y+  DL D  +++D  +Y++ K+ LV++   E          + +L+  S ++ +++H + F+     F     + +Q V  D +
Sbjct:  105 QIHGEQMSQLQINHQTQCDLLEDLRTFSLKRVAVEKDYAQALQKLA-NQYLKRDWPDSEKDEEPDHR--NMYWVWKAYLEATVQATQSRISSCENYKVQVADPAKTARLQKEQQLRKCIEQLTVVQAELQESVKELTKSRKKYQEAELMAQAVR----DKAELEAKSRLSLFQSKSSLQRATVKLKAKRNECSSKATHARNDYLLTLAAANAHQRRYYTTDLMDCIKVLDGRIYEQVKDYLVSLCQTELETYQAVHDTFNQLLNSSTRVAQEFHQQFFVQKNLLFQQSPDFSYQPVDSDTV 398
[Close]
BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Match: SMESG000023477.1 (SMESG000023477.1)

HSP 1 Score: 1464.13 bits (3789), Expect = 0.000e+0
Identity = 777/814 (95.45%), Postives = 778/814 (95.58%), Query Frame = 2 
Query:  125 MSIQXXXXXXXXXXXXXQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYXXXXXXXXXXXXXDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADLSPICPRIEPRKRPKIKLNFEKIKPVQNPNVNADTMTSETDVVGDYVRLASENEAKTEGDNLNVS 2566
            MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEK SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKS ELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT                                 PNVNADTMTSETDVVGDYVRLASENE KTEGDNLNV+
Sbjct:    1 MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKFSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKSAELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTY--------------------------------PNVNADTMTSETDVVGDYVRLASENEVKTEGDNLNVN 782
[Close]
BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Match: SMESG000023477.1 (SMESG000023477.1)

HSP 1 Score: 1408.66 bits (3645), Expect = 0.000e+0
Identity = 742/744 (99.73%), Postives = 742/744 (99.73%), Query Frame = 2 
Query:  125 MSIQXXXXXXXXXXXXXQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYXXXXXXXXXXXXXDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT 2356
            MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEK SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKS ELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT
Sbjct:    1 MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKFSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKSAELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT 744
[Close]
BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Match: SMESG000023477.1 (SMESG000023477.1)

HSP 1 Score: 1389.02 bits (3594), Expect = 0.000e+0
Identity = 751/814 (92.26%), Postives = 753/814 (92.51%), Query Frame = 2 
Query:  125 MSIQXXXXXXXXXXXXXQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAXXXXXXXXXXXXACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYXXXXXXXXXXXXXDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADLSPICPRIEPRKRPKIKLNFEKIKPVQNPNVNADTMTSETDVVGDYVRLASENEAKTEGDNLNVS 2566
            MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEK SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKS ELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYK+                       KYI        L P                          NVNADTMTSETDVVGDYVRLASENE KTEGDNLNV+
Sbjct:    1 MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAAADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQEMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNKLSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVYDRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPSFNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMGYEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELKFAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKFSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKSAELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKI-----------------------KYIF-------LDP--------------------------NVNADTMTSETDVVGDYVRLASENEVKTEGDNLNVN 758
[Close]
BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Match: SMESG000006893.1 (SMESG000006893.1)

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 352/389 (90.49%), Postives = 353/389 (90.75%), Query Frame = 2 
Query: 1400 DTDKILDDARTTVAAAAEMMKQNRSSEMDYXXXXXXXXXXXXXDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADLSPICPRIEPRKRPKIKLNFEKIKPVQNPNVNADTMTSETDVVGDYVRLASENEAKTEGDNLNVS 2566
            DTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEK SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKS ELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT                                 PNVNADTMTSETDVVGDYVRLASENE KTEGDNLNV+
Sbjct:    1 DTDKILDDARTTVAAAAEMMKQNRSSEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKFSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKSAELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTY--------------------------------PNVNADTMTSETDVVGDYVRLASENEVKTEGDNLNVN 357
[Close]
BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Match: SMESG000006893.1 (SMESG000006893.1)

HSP 1 Score: 577.4 bits (1487), Expect = 0.000e+0
Identity = 306/343 (89.21%), Postives = 307/343 (89.50%), Query Frame = 2 
Query: 1538 DYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTXXXXXXXXXXXXXIADYVNVLPISKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADLSPICPRIEPRKRPKIKLNFEKIKPVQNPNVNADTMTSETDVVGDYVRLASENEAKTEGDNLNVS 2566
            DYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEK SIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKS ELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNT                                 PNVNADTMTSETDVVGDYVRLASENE KTEGDNLNV+
Sbjct:    1 DYDEELSQINNEESFPYSLSKYSGYEYQPGSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKFSIDCEEDWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVRSLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPISKVKSAELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRVSQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTY--------------------------------PNVNADTMTSETDVVGDYVRLASENEVKTEGDNLNVN 311
The following BLAST results are available for this feature:
BLAST of FCH and double SH3 domains protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
FCHSD21.058e-4133.18FCH and double SH3 domains 2 [Source:HGNC Symbol;A... [more]
FCHSD26.090e-4035.00FCH and double SH3 domains 2 [Source:HGNC Symbol;A... [more]
FCHSD29.564e-2931.17FCH and double SH3 domains 2 [Source:HGNC Symbol;A... [more]
FCHSD21.410e-2831.17FCH and double SH3 domains 2 [Source:HGNC Symbol;A... [more]
FCHSD16.798e-2826.38FCH and double SH3 domains 1 [Source:HGNC Symbol;A... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FCH and double SH3 domains protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
nwk5.086e-4229.76gene:FBgn0263456 transcript:FBtr0344238[more]
nwk6.090e-4229.76gene:FBgn0263456 transcript:FBtr0309276[more]
nwk6.899e-4229.76gene:FBgn0263456 transcript:FBtr0344242[more]
nwk7.530e-4229.76gene:FBgn0263456 transcript:FBtr0309277[more]
nwk9.153e-4229.76gene:FBgn0263456 transcript:FBtr0309280[more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-176g13.81.619e-3327.32si:ch211-176g13.8 [Source:ZFIN;Acc:ZDB-GENE-091204... [more]
srgap1a3.173e-1123.67SLIT-ROBO Rho GTPase activating protein 1a [Source... [more]
srgap1b2.847e-1024.10SLIT-ROBO Rho GTPase activating protein 1b [Source... [more]
srgap1b2.936e-1024.10SLIT-ROBO Rho GTPase activating protein 1b [Source... [more]
CABZ01070631.27.822e-832.74F-BAR and double SH3 domains protein 2-like [Sourc... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tmem2094.639e-3829.78transmembrane protein 209 [Source:Xenbase;Acc:XB-G... [more]
tmem2094.725e-3829.78transmembrane protein 209 [Source:Xenbase;Acc:XB-G... [more]
tmem2096.132e-3829.78transmembrane protein 209 [Source:Xenbase;Acc:XB-G... [more]
tmem2097.651e-3730.50transmembrane protein 209 [Source:Xenbase;Acc:XB-G... [more]
cilp22.256e-3228.77cartilage intermediate layer protein 2 [Source:Xen... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Fchsd21.379e-4232.94FCH and double SH3 domains 2 [Source:MGI Symbol;Ac... [more]
Fchsd26.048e-4134.78FCH and double SH3 domains 2 [Source:MGI Symbol;Ac... [more]
Fchsd12.749e-2724.33FCH and double SH3 domains 1 [Source:MGI Symbol;Ac... [more]
Fchsd21.884e-2035.90FCH and double SH3 domains 2 [Source:MGI Symbol;Ac... [more]
Srgap11.233e-1023.67SLIT-ROBO Rho GTPase activating protein 1 [Source:... [more]
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BLAST of FCH and double SH3 domains protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q3USJ8|FCSD2_MOUSE9.649e-4232.94F-BAR and double SH3 domains protein 2 OS=Mus musc... [more]
sp|O94868|FCSD2_HUMAN5.082e-4133.18F-BAR and double SH3 domains protein 2 OS=Homo sap... [more]
sp|X2JAU8|NWK_DROME1.177e-4029.76Protein nervous wreck OS=Drosophila melanogaster O... [more]
sp|Q86WN1|FCSD1_HUMAN3.265e-2726.38F-BAR and double SH3 domains protein 1 OS=Homo sap... [more]
sp|Q6PFY1|FCSD1_MOUSE1.923e-2624.33F-BAR and double SH3 domains protein 1 OS=Mus musc... [more]
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BLAST of FCH and double SH3 domains protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A419PNJ84.089e-10243.34F-BAR and double SH3 domains protein 2 OS=Clonorch... [more]
A0A075ADU29.379e-10243.34Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A095CDA49.719e-10145.14FCH and double SH3 domains protein 2 OS=Schistosom... [more]
A0A430QJL92.463e-10044.91F-BAR and double SH3 domains protein OS=Schistosom... [more]
A0A087W2523.399e-9944.26Fch and double sh3 domains protein 2 OS=Echinococc... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-176g13.81.349e-3529.86si:ch211-176g13.8 [Source:ZFIN;Acc:ZDB-GENE-091204... [more]
ENSAMXT00000014010.23.762e-3430.68pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
srgap1b9.903e-1223.68SLIT-ROBO Rho GTPase activating protein 1b [Source... [more]
srgap1a3.921e-1023.76SLIT-ROBO Rho GTPase activating protein 1 [Source:... [more]
srgap1a4.395e-1023.76SLIT-ROBO Rho GTPase activating protein 1 [Source:... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FCH and double SH3 domains protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of FCH and double SH3 domains protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO389991.308e-4431.13Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO468657.336e-722.41Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of FCH and double SH3 domains protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000042060.13.150e-3830.02FCH and double SH3 domains 2 [Source:NCBI gene;Acc... [more]
ENSORLT00000012890.36.316e-3730.02FCH and double SH3 domains 2 [Source:NCBI gene;Acc... [more]
ENSORLT00000044556.16.790e-3529.08FCH and double SH3 domains 2 [Source:NCBI gene;Acc... [more]
si:ch211-176g13.81.072e-3227.91F-BAR and double SH3 domains protein 2 [Source:NCB... [more]
si:ch211-176g13.81.379e-3227.91F-BAR and double SH3 domains protein 2 [Source:NCB... [more]
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BLAST of FCH and double SH3 domains protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023477.10.000e+095.45SMESG000023477.1[more]
SMESG000023477.10.000e+099.73SMESG000023477.1[more]
SMESG000023477.10.000e+092.26SMESG000023477.1[more]
SMESG000006893.10.000e+090.49SMESG000006893.1[more]
SMESG000006893.10.000e+089.21SMESG000006893.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025026 ID=SMED30025026|Name=FCH and double SH3 domains protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2767bp
TATTTATTTAAAATTATTAGAAATAAACTCTATTAGATTTAAGTGCTTTT
ATGAATAACTAAATATAGTATTTTTTTAAAAATAAATTAGAGAATTTCAT
AAGTTTTTGTAAAATATTTAACTCATGTCTATTCAAACCATAAAAAAGAC
TCCTAAACCATTAATTCTCCTCAAACAAATACAGAATGAACATTTTATCG
ATCTCCAGAAAAAGCATTTATCCGATACAGATTTAATTGAAGATATTCGA
CAGTTCTGCAAACAGAAAGCGGCAGCAGATAGAGAATATGCTCAATCTAT
GCAAAAATTAATTCTAAACCTTTTGGCAAAGCGACATTTTCCCGCCAAAG
AGAATTGCAAAGAAAACGATTCTGAAGATTTAAATGTTTGGAGTACATGG
AGGGATTTATTAAATCAGTATCAAGAATCAGCAAACCTACGATTGAATAC
CGCTGATTTGTTACAGAAACTCAGCGACCAATTAAAACCGATCCGAATCA
ATCGATTATCTACGAATAAGCGGATATTAGACCAATTAAAGTTGTTGCAA
ACTGACTTATACACTTGTGTGCAAGAAATGATTAAGGCCCAAAAAGTTTA
TTCAGAAGAAGAGAAACAAGCTCATGAAATTCGAATTAAAGCACAAGACG
CAGCAGAAAAAGTCAAGAATAAGTCTACTAATATTTTTAATTCAATGGCC
AATCTCCACAAAAACAGTAACAAGCTCAGCAGTCGGCTAGATGCATATCA
GACTCGGTCTACAGCTGCACGGAATGAATACCTTTTTCAACTGGCCGCTA
TCAATGCTCACCTTTTCAGCTATTTTCACGTCGATTTGGGAGATTATGCA
CAGATAATTGATGCCGATGTCTATGATAGATTCAAGGAATTACTTGTAAC
AATTACAGCAGATGAACAAAACTGCTCTATGAAACAAAGTCAAGTTTGGT
TGAAATTGATCAAAAAATCAGAAAAGATATGCAGAAAATATCATTGGGAA
ATTTTTCTTAACAATTATCCATCATTCAATGCTCCAGTGCAATACAAATT
TCAATCTGTTAAAGGGGATAAGATTCATTTACTAGTTCCTTTAAATTTAA
AAGAAAATACTCTTGCCAATGTCACAAAAAAACTTGTCAAAAGGCTCATA
GTACGCGAGCATAAAATTATGGGCTATGAAAAAGAAGTCAAATCATTTGA
AACGGGACGAGTAACTCCTATTCAAAGCGCCACTCTGAGCCCTGCTGCAG
ACAGCGAAGTCGGTGTGGAAGATTTAATATCATATAACCAAGAATATGTA
GAGCATAAAGTTGAAGAATTAAAATTCGCGATTCGCAAAGAAAAGATTGA
AAAAAGCAAAATTGAAGCTTGTTTGGGTTTGCTTAAAGACTCAGGAGTTG
ATACTGATAAAATTTTGGACGATGCTCGCACTACTGTTGCGGCTGCGGCG
GAAATGATGAAGCAGAATAGGAGTTCCGAAATGGACTACTCTTCGCCCTC
AATAAGCATAGAGATTGAACAACCAATTGATAATCCGGATTACGATGAAG
AATTAAGTCAAATTAATAACGAAGAGAGCTTTCCATATTCTTTATCTAAA
TATTCAGGTTATGAATACCAACCTGGTAGTGCTTGCTCTACTCCAAATAA
ACCGCAGTCATACGCCTCTACAGTTACCAAGTCATCCGACAGCCGTGAGT
CTATAAATCACGAAATAATTTCAACAAAAGCCGATATTAACAACGAAGAG
AAAGTTAGTATAGATTGCGAAGAAGATTGGGTGGGGGATGGAGGATATGG
AAGAGCAGTTGCTATATTTGAATTTCAAGCTAGTTCAGGTCAATGGGAAG
AATTGGATCTTGTTGTTAATGAAGAAGTTATTCTTCTCAATGCAAGTGAA
ACAGATGGCTGGATTAAAGTTAGAAGTCTAATCGACGGCAGAGAAGGAAT
AGTTCCAATGAGTTATTTGAAAGTAATATATTCCTGTATTCCTCAGTCTG
TAACAAATGAAGAGGAAAATAAAAACAAAGATGACTATGAAAATATAGCA
GACTATGTAAACGTATTACCTATATCTAAAGTGAAGTCTACGGAGTTGCT
TTCTAATACAAATAAGCTCATTGATGGAAGCGATCTTGTAAAAACCACCT
ATGCATTTAGTAGCACAAATTCAGATGAGTTACAACTTGAGAAAAATGAC
ATAATACAAATAATTAGTCGAGTTTCCCAGGACGGAGTTGACGATGGATG
GTGGGAAGGATATAAGGTAATTTGGAATGAGGAGAAAAATTGCTGGGTAA
TTCTTCAACGTGGTTTTTTTCCTTCAATGGTTGTTCGGAAGTATATAGTG
AATACATTGTCGAAAGCAGATCTGAGTCCAATCTGTCCCAGGATTGAACC
GCGGAAACGGCCTAAAATCAAATTAAATTTTGAAAAAATCAAACCTGTAC
AAAACCCAAATGTAAATGCTGATACAATGACTAGTGAAACTGATGTGGTC
GGAGATTATGTTCGTTTGGCATCGGAAAATGAAGCAAAAACTGAGGGCGA
TAATTTAAATGTATCCTCAACAAATCTGTTAATTATCATTAATTGCCTGT
AGCTTAAAGTTTATACGTATTTTACATTTTCGTCATAAATCGTAGTGTGG
TATTTAGTCAATGGCCACAGGTGACAATTAAACTTGCTTCGCTACAGGTT
TTATTGATAAAAAAAATATTAGTTATTAGAAAATTTTAAAATGGAAAATG
GCTATCGATGATGATTC
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protein sequence of SMED30025026-orf-1

>SMED30025026-orf-1 ID=SMED30025026-orf-1|Name=SMED30025026-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=826bp
MSIQTIKKTPKPLILLKQIQNEHFIDLQKKHLSDTDLIEDIRQFCKQKAA
ADREYAQSMQKLILNLLAKRHFPAKENCKENDSEDLNVWSTWRDLLNQYQ
ESANLRLNTADLLQKLSDQLKPIRINRLSTNKRILDQLKLLQTDLYTCVQ
EMIKAQKVYSEEEKQAHEIRIKAQDAAEKVKNKSTNIFNSMANLHKNSNK
LSSRLDAYQTRSTAARNEYLFQLAAINAHLFSYFHVDLGDYAQIIDADVY
DRFKELLVTITADEQNCSMKQSQVWLKLIKKSEKICRKYHWEIFLNNYPS
FNAPVQYKFQSVKGDKIHLLVPLNLKENTLANVTKKLVKRLIVREHKIMG
YEKEVKSFETGRVTPIQSATLSPAADSEVGVEDLISYNQEYVEHKVEELK
FAIRKEKIEKSKIEACLGLLKDSGVDTDKILDDARTTVAAAAEMMKQNRS
SEMDYSSPSISIEIEQPIDNPDYDEELSQINNEESFPYSLSKYSGYEYQP
GSACSTPNKPQSYASTVTKSSDSRESINHEIISTKADINNEEKVSIDCEE
DWVGDGGYGRAVAIFEFQASSGQWEELDLVVNEEVILLNASETDGWIKVR
SLIDGREGIVPMSYLKVIYSCIPQSVTNEEENKNKDDYENIADYVNVLPI
SKVKSTELLSNTNKLIDGSDLVKTTYAFSSTNSDELQLEKNDIIQIISRV
SQDGVDDGWWEGYKVIWNEEKNCWVILQRGFFPSMVVRKYIVNTLSKADL
SPICPRIEPRKRPKIKLNFEKIKPVQNPNVNADTMTSETDVVGDYVRLAS
ENEAKTEGDNLNVSSTNLLIIINCL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003779actin binding
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0016592mediator complex
GO:0008290F-actin capping protein complex
Vocabulary: biological process
TermDefinition
GO:0051693actin filament capping
GO:0051016barbed-end actin filament capping
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000142posterior region of the whole animal
PLANA:0000418head
PLANA:0002032epidermal cell
PLANA:0002056medial muscle cell
Vocabulary: INTERPRO
TermDefinition
IPR027267AH/BAR_dom_sf
IPR036028SH3-like_dom_sf
IPR001452SH3_domain
IPR001060FCH_dom
IPR031160F_BAR
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 191..211
NoneNo IPR availableCOILSCoilCoilcoord: 159..179
NoneNo IPR availableGENE3DG3DSA:2.30.30.40coord: 670..741
e-value: 3.6E-12
score: 47.6
NoneNo IPR availableGENE3DG3DSA:2.30.30.40coord: 557..620
e-value: 3.8E-10
score: 41.1
NoneNo IPR availablePANTHERPTHR15735FCH AND DOUBLE SH3 DOMAINS PROTEINcoord: 15..740
NoneNo IPR availablePANTHERPTHR15735:SF10NERVOUS WRECK, ISOFORM Icoord: 15..740
IPR001452SH3 domainPRINTSPR00452SH3DOMAINcoord: 684..699
score: 30.96
coord: 728..740
score: 34.54
coord: 559..569
score: 25.4
coord: 706..715
score: 35.64
IPR001452SH3 domainSMARTSM00326SH3_2coord: 559..619
e-value: 7.0E-8
score: 42.2
coord: 670..741
e-value: 1.9E-10
score: 50.7
IPR001452SH3 domainPFAMPF00018SH3_1coord: 562..611
e-value: 4.9E-6
score: 26.0
coord: 676..712
e-value: 4.7E-6
score: 26.1
IPR001452SH3 domainPROSITEPS50002SH3coord: 556..620
score: 18.624
IPR001452SH3 domainPROSITEPS50002SH3coord: 667..742
score: 19.409
IPR001060FCH domainPFAMPF00611FCHcoord: 27..107
e-value: 5.6E-11
score: 42.6
IPR027267AH/BAR domain superfamilyGENE3DG3DSA:1.20.1270.60coord: 18..301
e-value: 1.7E-37
score: 131.1
IPR027267AH/BAR domain superfamilySUPERFAMILYSSF103657BAR/IMD domain-likecoord: 27..308
IPR031160F-BAR domainPROSITEPS51741F_BARcoord: 10..290
score: 14.587
IPR036028SH3-like domain superfamilySUPERFAMILYSSF50044SH3-domaincoord: 552..625
IPR036028SH3-like domain superfamilySUPERFAMILYSSF50044SH3-domaincoord: 646..768