Transferase caf17 mitochondrial-like protein

Overview
NameTransferase caf17 mitochondrial-like protein
Smed IDSMED30025003
Length (bp)1304
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Transferase caf17 mitochondrial-like protein (SMED30025003) t-SNE clustered cells

Violin plots show distribution of expression levels for Transferase caf17 mitochondrial-like protein (SMED30025003) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transferase caf17 mitochondrial-like protein (SMED30025003) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transferase caf17 mitochondrial-like protein (SMED30025003) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30025003

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 1

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X2 cellSMED30025003SMESG000026669.1 SmedASXL_015301SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Human
Match: IBA57 (iron-sulfur cluster assembly factor IBA57 [Source:HGNC Symbol;Acc:HGNC:27302])

HSP 1 Score: 149.828 bits (377), Expect = 1.195e-40
Identity = 102/323 (31.58%), Postives = 155/323 (47.99%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSI-------YSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPEN-QSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWP 1262
            L  R+L+ V G D   FL GL+TN++     +           Y+ FLN +GR LYDVI+YG    S     F  ECD  V  ++ +HL +YR+R+K+ +       ++ + P + ++    SL+        L+    DPR      R +  D+    ++ G +     +Y + R + GV EG  +   G  LPLE N   MNG++F KGCYIGQELTART+H GV+RKR+ PVRF     D L T+        +  SG  +G+  +      GLA +  S  +     ++A+            E +++ +    P WWP
Sbjct:   53 LDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSG-FLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILI---RDPRTARMGWRLLTQDEGPA-LVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRF----LDPLPTSGITPGATVLTASGQTVGKFRAGQG-NVGLALL-WSEKIKGPLHIRAS------------EGAQVALAASVPDWWP 352
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Celegans
Match: F39H2.3 (pep chromosome:WBcel235:I:8664925:8666499:1 gene:WBGene00009563.1 transcript:F39H2.3.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F39H2.3)

HSP 1 Score: 134.806 bits (338), Expect = 3.390e-36
Identity = 95/328 (28.96%), Postives = 156/328 (47.56%), Query Frame = 3 
Query:  291 TQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDVL 1274
            TQR      L  R L+++ G+D  +FLQGLITND+  +  + N + +  LN+KGR++ DV+++         +  + EC       + + +  YRLRK++EI     ++  +   E+ S+                    DPR   +  R  G   S E   +  K      Y   R  AG+ EG+ E  + + LP + NGD++N ++ +KGCY+GQELTART HTGV+R+R++P   +     +++  A     + +DE    +G++IS D   R L  ++LSS                 F+S K+    + +    P W P  +L
Sbjct:    3 TQRLI---KLPHRVLLKLHGSDTNAFLQGLITNDVTKL-QTQNGLAAFLLNTKGRIVEDVLLW-----RRGTDDLFLECSKENKTILTKEILKYRLRKQVEITE---SSDQIFFTEDVSDK---------------QAHRDPRFSGFGARVFGNPSSSEVSENREK------YENLRRSAGIAEGSQE--LAELLPFQANGDLLNMVSLDKGCYVGQELTARTAHTGVIRRRILPFECE----GQVKIGA-----EVLDEKKNKVGKIISSDTT-RCLGILQLSS-----------------FKSQKLTADGVSLTAKQPEWMPDKIL 268
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Celegans
Match: F39H2.3 (pep chromosome:WBcel235:I:8664976:8666497:1 gene:WBGene00009563.1 transcript:F39H2.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F39H2.3)

HSP 1 Score: 134.806 bits (338), Expect = 3.390e-36
Identity = 95/328 (28.96%), Postives = 156/328 (47.56%), Query Frame = 3 
Query:  291 TQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDVL 1274
            TQR      L  R L+++ G+D  +FLQGLITND+  +  + N + +  LN+KGR++ DV+++         +  + EC       + + +  YRLRK++EI     ++  +   E+ S+                    DPR   +  R  G   S E   +  K      Y   R  AG+ EG+ E  + + LP + NGD++N ++ +KGCY+GQELTART HTGV+R+R++P   +     +++  A     + +DE    +G++IS D   R L  ++LSS                 F+S K+    + +    P W P  +L
Sbjct:    3 TQRLI---KLPHRVLLKLHGSDTNAFLQGLITNDVTKL-QTQNGLAAFLLNTKGRIVEDVLLW-----RRGTDDLFLECSKENKTILTKEILKYRLRKQVEITE---SSDQIFFTEDVSDK---------------QAHRDPRFSGFGARVFGNPSSSEVSENREK------YENLRRSAGIAEGSQE--LAELLPFQANGDLLNMVSLDKGCYVGQELTARTAHTGVIRRRILPFECE----GQVKIGA-----EVLDEKKNKVGKIISSDTT-RCLGILQLSS-----------------FKSQKLTADGVSLTAKQPEWMPDKIL 268
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Fly
Match: CG8043 (gene:FBgn0037610 transcript:FBtr0081902)

HSP 1 Score: 157.532 bits (397), Expect = 6.625e-44
Identity = 108/337 (32.05%), Postives = 161/337 (47.77%), Query Frame = 3 
Query:  294 QRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHN--SIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVG--------LDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLV-DFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDV 1271
            QR F  E L +R L+ V G +   FLQGL TND+  I +     S+Y+ FLN  GR+LYD I+Y    +++N      ECD        RHL  YR+R++IE+  ++      +   N  ++ E++ +P       ++   DPR+     R +         L +      +    + DN+Y   R   GV EG  E   GK  PLE N D ++G++F+KGCY+GQELTAR +H+GV+RKR MP+R        L    D G   D    +G  +G++  F A   G+A +R+  ++    +L     DG                V  P WWP D+
Sbjct:   35 QRNFTLEPLGNRELIRVHGAEVVPFLQGLATNDVARIQSPGGPASMYAHFLNKAGRLLYDTILY----RTNNPETILVECDREASSDFRRHLRTYRVRRRIEVDSVDDEYTPWVM-FNLKDASEAVPNP----HPDLFVSPDPRLHVLGTRILAPTDMDWSKLSKCFADFGTATAASSDNSYQLLRYKQGVGEGCSELTPGKCFPLEANADYLHGVSFHKGCYVGQELTARVHHSGVIRKRYMPIR--------LTAPIDVGSSQDVTSLAGAKLGRVFGF-AHKHGIALLRIEKVLNGRPELMI---DGE------------RCYVERPEWWPEDL 338
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Zebrafish
Match: iba57 (iron-sulfur cluster assembly factor IBA57 [Source:NCBI gene;Acc:100330979])

HSP 1 Score: 162.54 bits (410), Expect = 1.387e-45
Identity = 106/346 (30.64%), Postives = 170/346 (49.13%), Query Frame = 3 
Query:  255 YFCKNYYAICSFTQR-------YFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIG-NSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPR--IKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWP 1262
            + C +   I + +Q        +F    L  R+++ V G D  SFLQG+ITND+N +G +S N++Y+  LN +GR LYD+I+Y         N    ECD  V DSV++ L +Y++R+K+ +      +++ + P ++   L   +  +   + ++    DPR  +  W +     D  ++ I+S  +      Y   R   G+ EG  +   G+ LPLE N   M GI+F+KGCYIGQELTART+HTGV+RKR+MPV    +  +KL   +       +   GG             GL+ VRL+    + + L+   S           +  + ++   P WWP
Sbjct:   26 FLCTSRTRIKTHSQTRAASSTAHFSCYRLPHRTVLNVSGQDTSSFLQGIITNDMNLLGEDSLNAMYAHVLNVQGRTLYDIILYSLKGNPDGLNGVLLECDSTVQDSVMQLLKVYKIRRKVNLSVCPSLSLWALLPHSKEAVLG--RPDVTTTDKVLVLEKDPRTELMGWRMITSAQDNPLD-IVSACRLGNTEEYHRHRYEIGLPEGVGDLPPGEALPLEANLVYMQGISFSKGCYIGQELTARTHHTGVIRKRLMPVSLS-APAEKLNQGS------ALQTEGGKPAGKYRTGVDKLGLSLVRLAH---AKETLQLKSSG----------DETVTVLASVPDWWP 348
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Xenopus
Match: IBA57 (IBA57, iron-sulfur cluster assembly [Source:NCBI gene;Acc:100489125])

HSP 1 Score: 154.836 bits (390), Expect = 6.144e-43
Identity = 99/329 (30.09%), Postives = 161/329 (48.94%), Query Frame = 3 
Query:  282 CSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLD-QSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPH 1265
            C  T+R         R L+++ G D   FLQGLITND+  +  +  ++Y+  LN +GR L+DVI+Y    +    +    ECD   V  + +HL +Y  R+K+ I      +++ +   +Q +  +    P     + V   +DPR+++   R V    ++ + ++   +    N Y + R   GV EG  +   G  LPLE N   MNGI+F+KGCY+GQELTART+HTG++RKR++P+RF           A+    D +  +G   G+  +      GLA +R++ +    ++L    S G          S + +    P WWP 
Sbjct:   23 CPLTER---------RGLLQLRGPDPAMFLQGLITNDVQRL--AEGALYAHLLNVQGRSLFDVILYRLPTEHSETSAILLECDVAAVGPIQKHLSLYNFRRKVIICPCPELSVWAVISGSQKQDTQMPDLP-----SSVICAADPRVEAMGFRLVAQSGENPKKLLPETETGSYNEYTKHRYEQGVPEGVQDIPPGVALPLESNLVYMNGISFSKGCYLGQELTARTHHTGIIRKRLLPIRFSTPL------PAEAEGADILTSAGKPAGKYRAGHG-DIGLALLRMAHI---GEELHIKPSSG----------SSVSVKASIPEWWPQ 315
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Mouse
Match: Iba57 (IBA57 homolog, iron-sulfur cluster assembly [Source:MGI Symbol;Acc:MGI:3041174])

HSP 1 Score: 152.91 bits (385), Expect = 5.594e-42
Identity = 105/329 (31.91%), Postives = 152/329 (46.20%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGN-------SHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITP-ENQSESLESLKSPLIKNENLVYYGSDPRIK--SWLLRCVGLDQSVEPIMSGMKQAPD-NNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHA---PSWWP 1262
            L  R+LV V G D   FL GL TN++   G        S  + Y+ FLN +GR LYDVI+YG    +     F  ECD  V+ ++ +HL +Y++R+K+ +       ++ + P   Q+     L+    + E       DPR     W L    L Q   P +    Q  D  +Y + R   G+ EG  +   G  LPLE N   MNG++F KGCYIGQELTART+HTGV+RKR+ PV+ +                  +  SG   G +++  A G+     R       H  L    S+  +     I+ SE +++      P WWP
Sbjct:   53 LDGRALVRVRGPDAAPFLLGLSTNELPLSGPPTGAAQPSARAAYAHFLNVQGRTLYDVILYGLPECTEGAPSFLLECDSSVLGALQKHLSMYKIRRKVTVEPSPELHVWAVLPCVPQTSETAPLEE---RVEGTTMLIRDPRTARMGWRL----LTQDDGPALVPRGQLGDLQDYHKYRYQQGIPEGVCDLPPGMALPLESNLVFMNGVSFTKGCYIGQELTARTHHTGVIRKRLFPVKLEGP----------------LPASGVSPGAIVTVTATGQAAGKFRAGQ---GHVGLALLRSE-TIKGPLHIKTSESQLVAVTAVVPDWWP 354
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Mouse
Match: Iba57 (IBA57 homolog, iron-sulfur cluster assembly [Source:MGI Symbol;Acc:MGI:3041174])

HSP 1 Score: 50.0618 bits (118), Expect = 1.348e-6
Identity = 28/62 (45.16%), Postives = 35/62 (56.45%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGN-------SHNSIYSLFLNSKGRVLYDVIIYG 482
            L  R+LV V G D   FL GL TN++   G        S  + Y+ FLN +GR LYDVI+YG
Sbjct:   53 LDGRALVRVRGPDAAPFLLGLSTNELPLSGPPTGAAQPSARAAYAHFLNVQGRTLYDVILYG 114
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Match: sp|B8JMH0|CAF17_DANRE (Putative transferase CAF17 homolog, mitochondrial OS=Danio rerio OX=7955 GN=iba57 PE=3 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 1.047e-44
Identity = 106/346 (30.64%), Postives = 170/346 (49.13%), Query Frame = 3 
Query:  255 YFCKNYYAICSFTQR-------YFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIG-NSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPR--IKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWP 1262
            + C +   I + +Q        +F    L  R+++ V G D  SFLQG+ITND+N +G +S N++Y+  LN +GR LYD+I+Y         N    ECD  V DSV++ L +Y++R+K+ +      +++ + P ++   L   +  +   + ++    DPR  +  W +     D  ++ I+S  +      Y   R   G+ EG  +   G+ LPLE N   M GI+F+KGCYIGQELTART+HTGV+RKR+MPV    +  +KL   +       +   GG             GL+ VRL+    + + L+   S           +  + ++   P WWP
Sbjct:   26 FLCTSRTRIKTHSQTRAASSTAHFSCYRLPHRTVLNVSGQDTSSFLQGIITNDMNLLGEDSLNAMYAHVLNVQGRTLYDIILYSLKGNPDGLNGVLLECDSTVQDSVMQLLKVYKIRRKVNLSVCPSLSLWALLPHSKEAVLG--RPDVTTTDKVLVLEKDPRTELMGWRMITSAQDNPLD-IVSACRLGNTEEYHRHRYEIGLPEGVGDLPPGEALPLEANLVYMQGISFSKGCYIGQELTARTHHTGVIRKRLMPVSLS-APAEKLNQGS------ALQTEGGKPAGKYRTGVDKLGLSLVRLAH---AKETLQLKSSG----------DETVTVLASVPDWWP 348
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Match: sp|Q8CAK1|CAF17_MOUSE (Putative transferase CAF17 homolog, mitochondrial OS=Mus musculus OX=10090 GN=Iba57 PE=1 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 3.913e-41
Identity = 105/329 (31.91%), Postives = 152/329 (46.20%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGN-------SHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITP-ENQSESLESLKSPLIKNENLVYYGSDPRIK--SWLLRCVGLDQSVEPIMSGMKQAPD-NNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHA---PSWWP 1262
            L  R+LV V G D   FL GL TN++   G        S  + Y+ FLN +GR LYDVI+YG    +     F  ECD  V+ ++ +HL +Y++R+K+ +       ++ + P   Q+     L+    + E       DPR     W L    L Q   P +    Q  D  +Y + R   G+ EG  +   G  LPLE N   MNG++F KGCYIGQELTART+HTGV+RKR+ PV+ +                  +  SG   G +++  A G+     R       H  L    S+  +     I+ SE +++      P WWP
Sbjct:   53 LDGRALVRVRGPDAAPFLLGLSTNELPLSGPPTGAAQPSARAAYAHFLNVQGRTLYDVILYGLPECTEGAPSFLLECDSSVLGALQKHLSMYKIRRKVTVEPSPELHVWAVLPCVPQTSETAPLEE---RVEGTTMLIRDPRTARMGWRL----LTQDDGPALVPRGQLGDLQDYHKYRYQQGIPEGVCDLPPGMALPLESNLVFMNGVSFTKGCYIGQELTARTHHTGVIRKRLFPVKLEGP----------------LPASGVSPGAIVTVTATGQAAGKFRAGQ---GHVGLALLRSE-TIKGPLHIKTSESQLVAVTAVVPDWWP 354
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Match: sp|Q5T440|CAF17_HUMAN (Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 5.737e-40
Identity = 102/323 (31.58%), Postives = 155/323 (47.99%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSI-------YSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPEN-QSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWP 1262
            L  R+L+ V G D   FL GL+TN++     +           Y+ FLN +GR LYDVI+YG    S     F  ECD  V  ++ +HL +YR+R+K+ +       ++ + P + ++    SL+        L+    DPR      R +  D+    ++ G +     +Y + R + GV EG  +   G  LPLE N   MNG++F KGCYIGQELTART+H GV+RKR+ PVRF     D L T+        +  SG  +G+  +      GLA +  S  +     ++A+            E +++ +    P WWP
Sbjct:   53 LDGRTLLRVRGPDAAPFLLGLLTNELPLPSPAAAGAPPAARAGYAHFLNVQGRTLYDVILYGLQEHSEVSG-FLLECDSSVQGALQKHLALYRIRRKVTVEPHPELRVWAVLPSSPEACGAASLQERAGAAAILI---RDPRTARMGWRLLTQDEGPA-LVPGGRLGDLWDYHQHRYLQGVPEGVRDLPPGVALPLESNLAFMNGVSFTKGCYIGQELTARTHHMGVIRKRLFPVRF----LDPLPTSGITPGATVLTASGQTVGKFRAGQG-NVGLALL-WSEKIKGPLHIRAS------------EGAQVALAASVPDWWP 352
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Match: sp|Q7RYZ1|CAF17_NEUCR (Putative transferase caf-17, mitochondrial OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=caf-17 PE=3 SV=1)

HSP 1 Score: 147.517 bits (371), Expect = 1.729e-38
Identity = 87/230 (37.83%), Postives = 127/230 (55.22%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQ-FYFECDGRVVDSVIRHLCIYRLRKKIEIRHI---EGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMP 995
            L SR L+ V G D   FLQG+ITN+IN   N+ N  Y+ FL ++GRV++DVIIY +        Q F  E D     ++ +H+  Y+LR K  ++ +   E A  +     +Q+     L    ++N        DPR+ ++  R V    S    ++     P+++Y  +R + G+ EG  E + G  LPLE N D+MNGI+F KGCY+GQELT RT H GVVRKR++P
Sbjct:   59 LTSRRLISVSGPDASKFLQGVITNNINAPHNA-NGFYTGFLTAQGRVVHDVIIYPDDLGPEPGKQSFLIEVDADEAATLHKHIKRYKLRSKFNLKLLDPEERALYHSWNDVDQAGPWTKLIDE-VQNAGNARAVPDPRVPAFGSRVVVNQTSSSSPLTDGDLTPESSYHLRRFLLGIPEGQSEIISGTALPLESNMDVMNGIDFRKGCYVGQELTIRTKHRGVVRKRILP 286
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Match: sp|Q4P7A4|CAF17_USTMA (Putative transferase CAF17, mitochondrial OS=Ustilago maydis (strain 521 / FGSC 9021) OX=237631 GN=CAF17 PE=3 SV=1)

HSP 1 Score: 143.665 bits (361), Expect = 2.951e-37
Identity = 106/370 (28.65%), Postives = 168/370 (45.41%), Query Frame = 3 
Query:  276 AICSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNS------HNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVD--FVDESGGHIGQLISFD---------------ACGR--------GLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHA----PSWWPHDVLLP 1280
            A    T   +    +  R +V+V G D    LQGL++ND+  + ++       N +Y+ F+N +GR+L DV I+          ++  + D R + S++  +  ++LR K+++  +     +V+    Q+    S   P I  +  +    DPR  S   R V     +  + +         Y   R+  GV EGA +F     LPLE N D M+G++F KGCY+GQELTART+HTGVVRKR++P+ F   Y       A    VD  F  +   H+ ++ S                 A G+        GLA +RL  +    D   A+ +       F + +++ E  + A    PSWWPHD  +P
Sbjct:   41 AAADKTSSTWKLAKVPHRGVVQVSGRDTVKLLQGLVSNDVKALDSTTLTHQPPNMVYAGFMNPQGRMLADVFIHRQPANQDGSPRWLLDIDSRTLPSLVAFIKKFKLRSKVKLTDLS-TDYHVV----QAWDSNSQAPPTIAEKLSI----DPRSPSIGYRGVLSAAEILDVAAAASTVDGLEYTLHRITNGVAEGALDFPQASSLPLENNLDYMHGVDFRKGCYVGQELTARTHHTGVVRKRIVPLSF---YLAGTPPPASIHDVDPAFPHQLPTHLAEIRSKPISTASEAATKPARGKAAGKFTSGVYNVGLACLRLEQVRRWADSSSADPNSKHDALEFSVLSADGETTLLARPWIPSWWPHDQPVP 398
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Match: A0A154P2U7 (Putative transferase CAF17, mitochondrial OS=Dufourea novaeangliae OX=178035 GN=WN55_10164 PE=4 SV=1)

HSP 1 Score: 193.356 bits (490), Expect = 4.193e-54
Identity = 123/329 (37.39%), Postives = 184/329 (55.93%), Query Frame = 3 
Query:  312 ESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEK---------RLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDV 1271
            E L SRSL+ + G D  +FLQGLITND+  I     ++Y+LFLN KGRV+YDVIIY    KSH D+ FY ECD + VD + +HL +YR+R+KI+I +IE   I V    + S+ L    +    + N++ Y  DPR+    +R +  + ++E   S +K+  + N L           R   G+ EG D+   GK LPLE N D ++G++F+KGCYIGQELTARTYHTGVVRKR+MP+ F     ++L T + +     +DESG  +G+    +    GL  +R++                    +  +   ++++ +  P WWP ++
Sbjct:   39 EHLNSRSLLRIRGRDASNFLQGLITNDMKHIEEGAANLYALFLNIKGRVMYDVIIY----KSHEDDVFYIECDSKAVDPLQKHLKMYRVRRKIDIDNIENN-INVWALFDTSQYLNKNDA----DNNIMMY-EDPRLADLGIRILA-ESNIE--RSDIKKHLNFNALMSNNPLSYKAFRYTLGISEGVDDLPPGKPLPLEVNCDYLHGVSFHKGCYIGQELTARTYHTGVVRKRIMPLLF-----EELSTKSFSYDEKIIDESGNVVGKFRG-NEKEHGLGLMRITE----------------ALNAKSLTMLDMKLKISKPIWWPQEI 332
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Match: A0A023EWT1 (Putative transcription factor component of ccr4 transcriptional complex (Fragment) OS=Triatoma infestans OX=30076 PE=2 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 1.196e-53
Identity = 122/323 (37.77%), Postives = 180/323 (55.73%), Query Frame = 3 
Query:  312 ESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITP---ENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLIS-FDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHD 1268
            E LK R+++++ G  C  FLQGLITNDI  + N+  +IY++FLN+KGR+LYD IIY    K+   N F+ ECD   +D V RHL +Y++R+KI+I   E +   +  P   ENQ   +E  +  +I          DPR+     R V + Q    +  G ++A D +Y   R   G+ EG +E L+GK  PLE N D +NG++FNKGCYIGQELTART+HTGV+RKR+MP+       +    + D+ ++D       +IG+L   F+  G GL  +R++  + S              ++ KI N+ I+     P WWP +
Sbjct:   34 EQLKERTILKLKGEQCSEFLQGLITNDIK-VLNNQKAIYAMFLNTKGRILYDTIIY----KTDCKNTFFLECDTACMDDVERHLKVYKVRRKIDISRGEHSVWVIFKPNIQENQDFKIELSEKCII--------CPDPRLPDLGYRAV-VPQDANLVNDGNERA-DISYKMYRYKLGIPEGKEELLIGKCFPLEMNCDFLNGVSFNKGCYIGQELTARTHHTGVIRKRLMPLELLSLPEN---VSLDDPIIDTSTLKPSNIGKLRGIFENYGLGL--MRVTETLAS--------------KNLKIGNTNIK--CSKPLWWPTE 320
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Match: A0A2R7VYK2 (GCV_T domain-containing protein OS=Oncopeltus fasciatus OX=7536 GN=OFAS_OFAS002613 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.538e-53
Identity = 125/335 (37.31%), Postives = 180/335 (53.73%), Query Frame = 3 
Query:  303 FFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGA----AIY--------VITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAP-DNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYD-KLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPH 1265
            F  E L +R ++ + GND   FLQGLITND+N + N  +SIY++FLNSKGRVLYD  IY    K+   N FY +CD   V+ +++HL +YR+R+KI+I  ++      AIY         I+   +  +  +L S + + +       DPR+ S   R +     V      +++ P DN Y+  R   GV EG +EF +G+  PLE N D +NG++F+KGCYIGQELTART+HTGV+RKR+MP+ F++   D    T  D   V      G   G    F     GL  +R+S  +                +SFK+   +I+  V AP WWP+
Sbjct:   35 FSAEKLINRKVLRISGNDSCEFLQGLITNDMNILLNGSSSIYTMFLNSKGRVLYDAFIY----KTKRSNCFYVDCDNVCVEELVKHLKMYRVRRKIDISTLDSEYSVWAIYDSKIIDHLRISGRKEDVAAGTLTSLINETQVENIIACDPRLSSLGYRALITSDDV------LREIPLDNRYMSCRHKLGVGEGVNEFQIGQSFPLEINCDFLNGVSFDKGCYIGQELTARTFHTGVIRKRLMPLEFEKEPKDIPYDTVFDYSGVKRKSPLGKFKGSSGCF-----GLGLMRVSEALEC--------------KSFKL--LDIKTKVMAPYWWPN 338
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Match: A0A069DRJ9 (Putative transcription factor component of ccr4 transcriptional complex (Fragment) OS=Panstrongylus megistus OX=65343 PE=2 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 1.886e-53
Identity = 120/318 (37.74%), Postives = 174/318 (54.72%), Query Frame = 3 
Query:  312 ESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLIS-FDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWP 1262
            E LK R+++++ G  C  FLQGLITNDI  + N+  +IY++FLN+KGR+LYD IIY    K+   N F+ ECD   +D V RHL +Y++R+KI+I   E +   +  P NQ    +  K  L +         DPR+     R V + Q    + +G  + PD +Y   R   G+ EG  E  +GK  PLE N D +NG++FNKGCYIGQELTART+HTGV+RKR+MP+ F     +    + D+ ++D       ++G+L   F+  G GL  +R++  + S              +  KI N  I +    P WWP
Sbjct:   22 EQLKERTVLKLKGEQCSEFLQGLITNDIK-VLNNQKAIYAMFLNTKGRILYDTIIY----KTDCKNTFFLECDNACIDDVERHLKLYKVRRKIDISRGEHSVWVIFKPNNQEN--QDFKIELSEK---CIICPDPRLSDLGYRAV-VPQDANLVNNGNDE-PDISYKMYRYKLGIPEGKAELPIGKCFPLEMNCDYLNGVSFNKGCYIGQELTARTHHTGVIRKRLMPIEFLSLSEN---VSLDDPIIDTSTIKPSNVGKLRGIFENLGLGL--MRVTETLAS--------------KKLKIGN--ISVKCSKPPWWP 306
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Match: A0A4W4GKG2 (IBA57, iron-sulfur cluster assembly OS=Electrophorus electricus OX=8005 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.909e-53
Identity = 114/329 (34.65%), Postives = 170/329 (51.67%), Query Frame = 3 
Query:  300 YFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNS-HNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEP-IMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYD---KLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDV 1271
            +F   SL SRSLV++ G D  +FLQG+ITND+N +G     S+Y+  LN KGR LYDVIIY  S  S + N    ECD  ++ +V++HL +Y++R+++ +      +++ + P+    + + LK      E  +    DPR      R V  +    P  ++  +Q   + Y   R   G+ EGA +   G+ LPLE N   MNGI+F+KGCY+GQELTART+HTGVVRKR++PVR          +LR+  D      V +    +G++        GL  VR +    + + L+   S  R           + + V  P WWP D 
Sbjct:   51 HFICYSLPSRSLVQIHGQDTSAFLQGIITNDMNLLGEGRQRSLYAHMLNVKGRTLYDVIIYSLSESSADLNSIVLECDSSLLGAVVQHLTMYKIRRRVTVNTCADLSLWALLPQETRSASQQLKPEPTSAEKALVLVEDPRTDLMGWRLVARNSENPPDFIAACQQGDPDEYHSHRYKIGLPEGARDLPPGEALPLESNLVFMNGISFSKGCYLGQELTARTHHTGVVRKRLVPVRLSSPSLQAGAELRSPGDKP----VGKYRAGLGRV--------GLGLVRTAH---TDETLRLASSQDRT----------VTLEVSVPDWWPEDT 354
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Cavefish
Match: iba57 (iron-sulfur cluster assembly factor IBA57 [Source:NCBI gene;Acc:103035458])

HSP 1 Score: 170.629 bits (431), Expect = 1.077e-48
Identity = 110/324 (33.95%), Postives = 167/324 (51.54%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHN--SIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLE-SLKSPLIKNENLVYYGSDPR--IKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGR-GLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDV 1271
            L  RSL+ + G D  ++LQG+ITND+N +       ++Y+  LN +GR LYD+IIY     S +  +   ECDG V+DSV RHL +Y++R+++ +      A++ + P +   + + S   P      LV    DPR  +  W +   G  ++   +++  +      Y + R   G+ EG  +   G  LPLE N   MNGI+F+KGCYIGQELTART+HTGVVRKR++P+    +  D L+     G +D    +G   G+L +    GR GL  VRL+    ++D L    S           ++ +      P WWP D 
Sbjct:   60 LPGRSLLHIRGPDTCAYLQGIITNDMNLLQEEEERRALYAHMLNVQGRTLYDIIIYSVREPSGDPVEVLLECDGSVLDSVTRHLKVYKIRRRVTVTPRSDLALWALLPRDAGSARDGSQPRPTAAGRPLVLV-PDPRTDLMGWRM-ITGSSENPAELLTDCENRETEEYQQHRYTIGLPEGVADLPPGDALPLESNLVFMNGISFSKGCYIGQELTARTHHTGVVRKRLLPLSLS-AAGDALQP---GGALDST-AAGKPAGKLRA--GLGRQGLGLVRLAH---ANDTLTLKSS----------SSTPVTARASIPDWWPKDA 361
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Yeast
Match: IBA57 (Protein involved in incorporating iron-sulfur clusters into proteins; mitochondrial matrix protein; involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system [Source:SGD;Acc:S000003883])

HSP 1 Score: 92.4337 bits (228), Expect = 8.653e-21
Identity = 81/279 (29.03%), Postives = 123/279 (44.09%), Query Frame = 3 
Query:  393 INGIGNSHNSIYSLFLNSKGRVLYDVIIYGN----SHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESL---------ESLKSPLIKNENLV------------YYGSDPRI---------KSWLLRCVGLDQSVEPIMSGMKQAPDNNYL---------------------EKRLIAGVCEGADEFLVGKKLPLEFNGDIM-NGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDF 1061
            I G   S   +YS FLN KG+++ D IIY      S +  N  ++  E  G VVD ++  L  ++L  KI+   I+ +++     E Q  +L         ++L  P+   +N +             + SDPRI         +S         QS   + S  +Q  D + L                     E R   G+ +  ++++    LPLE N D   N I+ NKGCY+GQELTARTY TG++RKR++PV+ D   Y  L T  +    +F
Sbjct:  125 IQGPYISRFGLYSAFLNGKGKLITDTIIYPTPVTVSEQISNYPEYLLELHGNVVDKILHVLQTHKLANKIKFEKIDHSSLKTWDVEVQFPNLPKDIENPWFDNLLDPMALPKNSIDANNFAVNVLNSLFNSDPRILGIYVERRTESMSRHYSTFPQSFRVVTS--EQVDDLSKLFNFNVFDFPFQVNKKASVQVREIRFQKGLIDSTEDYISETLLPLELNFDFFPNTISTNKGCYVGQELTARTYATGILRKRLVPVKLDN--YQLLDTDPERKYAEF 399
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Nematostella
Match: EDO42091 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2C9])

HSP 1 Score: 177.948 bits (450), Expect = 2.948e-52
Identity = 119/329 (36.17%), Postives = 173/329 (52.58%), Query Frame = 3 
Query:  309 YESLKSRSLVEVIGNDCRSFLQGLITNDINGI-GNSH-NSIYSLFLNSKGRVLYDVIIYGNSHKSHNDN-QFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPL-IKNENLVYYGSDPRIKSWLLRCVGLDQSVEP--IMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGL---VDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHD 1268
            Y  L  R ++ V G D   FLQGL+TN+I    G+S   S+Y++FLN++GRVLYD I+  +  K+H++   F+ ECD  +  ++ +HL  ++LR K +I H EG   + +     SE +  LK     K+ ++V    DPR+K    R + L    +P   + G   AP   Y E R   GVCEG +E  +   +PLE+N D +NG++F+KGCYIGQELTART+HTGV+RKR+MP            T A N +        E+G   G++        GL  +RL++L     +L     DG+            EM  + P WWP D
Sbjct:   33 YSQLDKRCILRVSGPDSVKFLQGLVTNNIELFHGDSTIRSMYTMFLNAQGRVLYDAIL--SKDKTHSETPSFFIECDRSISAALTKHLKFFKLRSKADISHAEGLVPWTVF----SEEIVDLKPEEDWKDFSIV---PDPRVKKLGHRLI-LPSDTDPSACIEGAGHAPRGAYEEHRARLGVCEGEEEIPIANAMPLEYNLDFLNGVSFHKGCYIGQELTARTHHTGVIRKRIMPF-----------TIASNNISSGAAIKTEAGKASGKVCIVHG-QYGLGMIRLANL--KAGKLLVEAKDGQ----------HTEMRPYVPDWWPKD 327
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Medaka
Match: iba57 (iron-sulfur cluster assembly factor IBA57 [Source:NCBI gene;Acc:101156530])

HSP 1 Score: 165.236 bits (417), Expect = 1.061e-46
Identity = 111/327 (33.94%), Postives = 163/327 (49.85%), Query Frame = 3 
Query:  318 LKSRSLVEVIGNDCRSFLQGLITNDINGI--GNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPI--MSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGR---GLATVRLSSLVPSH--DQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDV 1271
            L  R+L+++ G D   FLQGLITND+  +       ++Y+  LN +GR LYDV++Y    K       + ECD  V DSV+RHL +Y++R+K+ I      +++ +         E+ +  L   E  + + +DPR      R V L +  +P+  +   ++     Y + R   GV EG  +   G  LPLE N   M GI+F+KGCYIGQELTART+HTGVVRKR+MPVR          ++   GL       G  + Q  S  A G+   G+  + LS +  +H  + L    SD          +S + +    P WWP DV
Sbjct:   57 LPHRALLKIHGTDTSPFLQGLITNDMGLLEEPGQAAAMYAHMLNVQGRTLYDVMLY--RMKEAEGLGVFLECDTTVHDSVLRHLRVYKIRRKVSISPCPELSVWAVLSLQNRPDQEAGQPELSAPEKALVWEADPRTSQMGWRLV-LQRETDPLDLIVPCEKGDTEEYQKHRYRIGVPEGVKDLPPGVALPLESNLVFMQGISFSKGCYIGQELTARTHHTGVVRKRLMPVRL---------SSPPKGL------QGETLLQTQSGKAAGKHRAGVGELGLSLIRTAHAKEMLTLKCSD----------DSTVTLEASVPDWWPKDV 355
[Close]
BLAST of Transferase caf17 mitochondrial-like protein vs. Planmine SMEST
Match: SMESG000026669.1 (SMESG000026669.1)

HSP 1 Score: 714.916 bits (1844), Expect = 0.000e+0
Identity = 345/346 (99.71%), Postives = 346/346 (100.00%), Query Frame = 3 
Query:  246 MLKYFCKNYYAICSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDVLLPV 1283
            MLKYFCKNYYAICSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAP+WWPHDVLLPV
Sbjct:    1 MLKYFCKNYYAICSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDINGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVDSVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENLVYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEGADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMPVRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSSLVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPNWWPHDVLLPV 346
The following BLAST results are available for this feature:
BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 1
Match NameE-valueIdentityDescription
IBA571.195e-4031.58iron-sulfur cluster assembly factor IBA57 [Source:... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
F39H2.33.390e-3628.96pep chromosome:WBcel235:I:8664925:8666499:1 gene:W... [more]
F39H2.33.390e-3628.96pep chromosome:WBcel235:I:8664976:8666497:1 gene:W... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
CG80436.625e-4432.05gene:FBgn0037610 transcript:FBtr0081902[more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
iba571.387e-4530.64iron-sulfur cluster assembly factor IBA57 [Source:... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
IBA576.144e-4330.09IBA57, iron-sulfur cluster assembly [Source:NCBI g... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Iba575.594e-4231.91IBA57 homolog, iron-sulfur cluster assembly [Sourc... [more]
Iba571.348e-645.16IBA57 homolog, iron-sulfur cluster assembly [Sourc... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|B8JMH0|CAF17_DANRE1.047e-4430.64Putative transferase CAF17 homolog, mitochondrial ... [more]
sp|Q8CAK1|CAF17_MOUSE3.913e-4131.91Putative transferase CAF17 homolog, mitochondrial ... [more]
sp|Q5T440|CAF17_HUMAN5.737e-4031.58Putative transferase CAF17, mitochondrial OS=Homo ... [more]
sp|Q7RYZ1|CAF17_NEUCR1.729e-3837.83Putative transferase caf-17, mitochondrial OS=Neur... [more]
sp|Q4P7A4|CAF17_USTMA2.951e-3728.65Putative transferase CAF17, mitochondrial OS=Ustil... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A154P2U74.193e-5437.39Putative transferase CAF17, mitochondrial OS=Dufou... [more]
A0A023EWT11.196e-5337.77Putative transcription factor component of ccr4 tr... [more]
A0A2R7VYK21.538e-5337.31GCV_T domain-containing protein OS=Oncopeltus fasc... [more]
A0A069DRJ91.886e-5337.74Putative transcription factor component of ccr4 tr... [more]
A0A4W4GKG21.909e-5334.65IBA57, iron-sulfur cluster assembly OS=Electrophor... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
iba571.077e-4833.95iron-sulfur cluster assembly factor IBA57 [Source:... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
IBA578.653e-2129.03Protein involved in incorporating iron-sulfur clus... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO420912.948e-5236.17Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
iba571.061e-4633.94iron-sulfur cluster assembly factor IBA57 [Source:... [more]
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BLAST of Transferase caf17 mitochondrial-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000026669.10.000e+099.71SMESG000026669.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30025003 ID=SMED30025003|Name=Transferase caf17 mitochondrial-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1304bp
TTCGAGCCCCAGTTTTGATGACTCAACAGAATTCAGTGAAGATGATGATG
GGCAGCTTTTCGGTGGTTTTAACAATAAGAACATTGATATTGCTGACGTG
TTTGATTGAATTAAATAAATATTTTTAAAAATCAGTTTTTTGTTAACTTT
TTAATTTATTTATTTGGAAAACTTGTAATAGTTTTTATTATGAAAATTTG
TTATAATTTTCATTTTTTTAATATTATTATTATTAATATTATATTATGTT
GAAATATTTTTGTAAGAATTATTATGCAATATGTTCCTTTACACAACGAT
ATTTTTTTTATGAATCTTTAAAATCAAGAAGTCTTGTTGAGGTTATTGGT
AATGATTGTAGAAGTTTTTTACAAGGTTTAATCACAAATGACATAAATGG
TATTGGAAATTCCCACAACTCGATTTATTCATTATTTTTGAATTCAAAAG
GACGTGTTTTATATGATGTTATCATTTATGGAAATTCTCACAAATCACAT
AATGATAATCAATTTTATTTTGAGTGTGATGGTAGAGTTGTTGATTCAGT
AATACGGCATTTGTGTATTTACAGATTGAGGAAGAAGATCGAAATAAGAC
ATATTGAAGGTGCCGCTATATATGTTATAACTCCTGAGAATCAATCTGAA
TCATTGGAGTCACTAAAATCTCCATTAATTAAAAATGAAAATCTCGTTTA
TTATGGATCGGATCCAAGGATAAAATCATGGTTATTACGATGTGTTGGTC
TTGATCAATCAGTGGAGCCAATAATGAGTGGAATGAAACAAGCTCCGGAT
AATAATTATTTGGAAAAGAGATTAATTGCAGGGGTTTGCGAAGGTGCGGA
TGAGTTTCTTGTTGGTAAGAAATTGCCATTGGAATTCAATGGTGACATCA
TGAATGGAATCAATTTTAATAAAGGATGTTACATTGGGCAGGAGTTAACA
GCACGCACATATCATACTGGAGTCGTAAGGAAACGGGTAATGCCGGTCAG
GTTCGATCGGTCATATTATGACAAATTGAGAACGGCAGCTGATAACGGAT
TGGTCGATTTTGTTGATGAATCAGGTGGGCACATTGGGCAATTGATATCT
TTCGATGCTTGTGGTCGCGGTTTAGCCACTGTACGCTTGTCGAGCTTGGT
TCCGTCACATGACCAGTTGAAAGCCAATGAGTCAGACGGGCGCGTATTCC
GATCATTCAAAATCGAGAACAGTGAGATTGAAATGATTGTTCATGCTCCT
AGTTGGTGGCCACATGATGTTCTGTTGCCGGTTTAAATATATTGATTTTG
TCTT
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protein sequence of SMED30025003-orf-1

>SMED30025003-orf-1 ID=SMED30025003-orf-1|Name=SMED30025003-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=347bp
MLKYFCKNYYAICSFTQRYFFYESLKSRSLVEVIGNDCRSFLQGLITNDI
NGIGNSHNSIYSLFLNSKGRVLYDVIIYGNSHKSHNDNQFYFECDGRVVD
SVIRHLCIYRLRKKIEIRHIEGAAIYVITPENQSESLESLKSPLIKNENL
VYYGSDPRIKSWLLRCVGLDQSVEPIMSGMKQAPDNNYLEKRLIAGVCEG
ADEFLVGKKLPLEFNGDIMNGINFNKGCYIGQELTARTYHTGVVRKRVMP
VRFDRSYYDKLRTAADNGLVDFVDESGGHIGQLISFDACGRGLATVRLSS
LVPSHDQLKANESDGRVFRSFKIENSEIEMIVHAPSWWPHDVLLPV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR017703YgfZ/GcvT_CS
IPR027266TrmE/GcvT_dom1
IPR006222GCV_T_N
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0016740transferase activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR017703YgfZ/GcvT conserved siteTIGRFAMTIGR03317TIGR03317coord: 187..252
e-value: 4.3E-20
score: 69.4
IPR006222Aminomethyltransferase, folate-binding domainPFAMPF01571GCV_Tcoord: 31..119
e-value: 1.1E-6
score: 28.3
IPR027266GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1GENE3DG3DSA:3.30.1360.120coord: 13..317
e-value: 2.4E-45
score: 157.0
NoneNo IPR availablePANTHERPTHR22602UNCHARACTERIZEDcoord: 21..341
NoneNo IPR availableSUPERFAMILYSSF103025Folate-binding domaincoord: 17..243