CCD25

Overview


Name	CCD25
Smed ID	SMED30024991
Length (bp)	737

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of CCD25 (SMED30024991) t-SNE clustered cells

Violin plots show distribution of expression levels for CCD25 (SMED30024991) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of CCD25 (SMED30024991) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for CCD25 (SMED30024991) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024991

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 5

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
X1 cell	SMED30024991	SMESG000046670.1	SmedASXL_010046	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30024991	SMESG000046670.1	SmedASXL_010046	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
nervous system	SMED30024991	SMESG000046670.1	dd_Smed_v4_4506_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30024991	SMESG000046670.1	dd_Smed_v4_4506_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30024991	SMESG000046670.1	dd_Smed_v4_4506_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of CCD25 vs. Ensembl Human
Match: CCDC25 (coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591])

HSP 1 Score: 214.542 bits (545), Expect = 9.429e-70
Identity = 114/201 (56.72%), Postives = 141/201 (70.15%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQGCK+NN++VVYT WSNLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER       +  +K EKE  ++K+   E + YS L     M SN+D
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFP-DLAAEKECRDREERNEKKAQIQEMKKREKEEMKKKREMDELRSYSSLMKVENMSSNQD 200

[Close]

BLAST of CCD25 vs. Ensembl Human
Match: CCDC25 (coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591])

HSP 1 Score: 129.028 bits (323), Expect = 7.289e-38
Identity = 58/83 (69.88%), Postives = 68/83 (81.93%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGC 307
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQG 
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQGA 83

[Close]

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGC 307
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQG 
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQGA 83

[Close]

BLAST of CCD25 vs. Ensembl Human
Match: CCDC25 (coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591])

HSP 1 Score: 129.028 bits (323), Expect = 9.483e-38
Identity = 58/82 (70.73%), Postives = 68/82 (82.93%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQG 304
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQG
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQG 82

[Close]

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQG 304
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQG
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQG 82

[Close]

BLAST of CCD25 vs. Ensembl Celegans
Match: Y54G11A.2 (pep chromosome:WBcel235:II:14252357:14255705:1 gene:WBGene00013213.1 transcript:Y54G11A.2.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y54G11A.2)

HSP 1 Score: 201.445 bits (511), Expect = 4.930e-65
Identity = 97/158 (61.39%), Postives = 119/158 (75.32%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKR 535
            MV  F SN    P  IYMG DK ENEDLIK+GWPEDVWFHVDKLSSAHVYLRL+   TI+S+PE+++ DC QLVK+NSI+GCKLNN+ +VYT WSNLKKT DM VGQVGFH +K V    V  K +E + RL KT+ +D   D+K  ++ RD+KER++
Sbjct:    1 MVIKFSSNTTNPPTMIYMGVDKVENEDLIKYGWPEDVWFHVDKLSSAHVYLRLHSGMTIDSIPEALLIDCCQLVKQNSIEGCKLNNVAIVYTMWSNLKKTGDMAVGQVGFHSHKQVKHTVVPTKINEIVNRLEKTRRKD-DIDYKEERDARDAKERQK 157

[Close]

BLAST of CCD25 vs. Ensembl Celegans
Match: F43C1.7 (pep chromosome:WBcel235:III:4241477:4242593:-1 gene:WBGene00023423.1 transcript:F43C1.7.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F43C1.7)

HSP 1 Score: 135.576 bits (340), Expect = 3.826e-40
Identity = 64/129 (49.61%), Postives = 88/129 (68.22%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETI 448
            MVF FIS+ V  P  I+MG  + ENE L K G P DVWFHVDK+SSAHVYL+L    TI+++PE ++++C QLVK+NSIQG K+  ++V YT   NLKK   M  G++GF+    + +  V KKN++ +
Sbjct:    1 MVFGFISSTVTPPALIFMGEHQVENEKLFKCGDPGDVWFHVDKVSSAHVYLQLPSGITIDTIPEELLEECCQLVKKNSIQGVKMEKVEVNYTLKENLKKVKGMQTGEIGFYDKNIIKSRSVLKKNTKKV 129

[Close]

BLAST of CCD25 vs. Ensembl Fly
Match: CG4593 (gene:FBgn0029929 transcript:FBtr0343331)

HSP 1 Score: 223.402 bits (568), Expect = 1.741e-73
Identity = 109/202 (53.96%), Postives = 150/202 (74.26%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMA 667
            MVFYF SNVV+ P  +YMGRDK ENE+LI+WGWPEDVWFHV  LSSAHVYLRL + +TI+ +P  V+ D AQL K NSIQG K+NN++VVYT W NLKKT DM+ GQV +H  K+V  IR++K+ +E + RLN+TK+E+   DF+ ++E RD+ ER+   + +R RR++EKE+ +Q+++EAE + Y+ L  +  M +N D  
Sbjct:    1 MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTDVLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVNRLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASLQKSENMRTNYDAG 202

[Close]

BLAST of CCD25 vs. Ensembl Fly
Match: CG4593 (gene:FBgn0029929 transcript:FBtr0071009)

HSP 1 Score: 223.402 bits (568), Expect = 1.741e-73
Identity = 109/202 (53.96%), Postives = 150/202 (74.26%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMA 667
            MVFYF SNVV+ P  +YMGRDK ENE+LI+WGWPEDVWFHV  LSSAHVYLRL + +TI+ +P  V+ D AQL K NSIQG K+NN++VVYT W NLKKT DM+ GQV +H  K+V  IR++K+ +E + RLN+TK+E+   DF+ ++E RD+ ER+   + +R RR++EKE+ +Q+++EAE + Y+ L  +  M +N D  
Sbjct:    1 MVFYFKSNVVQPPAMLYMGRDKHENEELIRWGWPEDVWFHVHDLSSAHVYLRLRKGQTIDDIPTDVLVDAAQLCKANSIQGNKVNNLEVVYTMWENLKKTPDMEPGQVAYHNEKAVRRIRLEKRINEIVNRLNRTKTEEEHPDFRGLREARDAAERQDQKKIQRERREQEKEAAKQRELEAELRSYASLQKSENMRTNYDAG 202

[Close]

BLAST of CCD25 vs. Ensembl Zebrafish
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:393359])

HSP 1 Score: 221.861 bits (564), Expect = 7.932e-73
Identity = 113/204 (55.39%), Postives = 149/204 (73.04%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVFYF S VV  P+TIYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI+ +P+ V+ DC QLVK NSIQGCK+NNI++VYT WSNLKKT DMD+GQ+GFH+ K V  + V+KK +E + RL KTK E+   D    KE RD +ER       + ++K+EKE  ++K+   + K+Y+ L  +  M +N+D  GY
Sbjct:    1 MVFYFTSAVVSPPHTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGTTIDDIPKEVLIDCVQLVKNNSIQGCKMNNINIVYTPWSNLKKTADMDIGQIGFHRQKEVKIVAVEKKINEIVNRLEKTK-EERYPDLAAEKESRDREERNEKKAQIQEQKKKEKEEVKKKKEMEDLKNYTSLMKSDNMTTNED--GY 201

[Close]

BLAST of CCD25 vs. Ensembl Xenopus
Match: CCDC25 (coiled-coil domain containing 25 [Source:HGNC Symbol;Acc:HGNC:25591])

HSP 1 Score: 129.798 bits (325), Expect = 2.915e-38
Identity = 54/77 (70.13%), Postives = 66/77 (85.71%), Query Frame = 2

Query:   74 FISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQG 304
            F   V+  PYT+YMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLRL +++TI  +P+ V+ DCAQLVK NSIQG
Sbjct:    6 FFPPVISPPYTMYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKDQTIEDIPKEVLLDCAQLVKANSIQG 82

[Close]

BLAST of CCD25 vs. Ensembl Mouse
Match: Ccdc25 (coiled-coil domain containing 25 [Source:MGI Symbol;Acc:MGI:1914429])

HSP 1 Score: 216.083 bits (549), Expect = 1.470e-70
Identity = 113/201 (56.22%), Postives = 142/201 (70.65%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLRL + E I  +P+ V+ DCA LVK NSIQGCK+NN++VVYT WSNLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER       +  +++EKE  ++K+   E + YS L     M SN+D
Sbjct:    1 MVFYFTSSSVNSSTYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKLEKFP-DLAAEKEGRDREERNEKKAQIQEMKRKEKEEMKKKREMDELRSYSSLMKVENMSSNQD 200

[Close]

BLAST of CCD25 vs. UniProt/SwissProt
Match: sp|Q6GLE1|CCD25_XENTR (Coiled-coil domain-containing protein 25 OS=Xenopus tropicalis OX=8364 GN=ccdc25 PE=2 SV=1)

HSP 1 Score: 224.557 bits (571), Expect = 5.260e-73
Identity = 114/200 (57.00%), Postives = 147/200 (73.50%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF SNV+  PYT+YMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLRL +++TI  +P+ V+ DCAQLVK NSIQGCK+NNI+VVYT W+NLKKT DMD+GQ+GFH+ K V T+ V+K  S+ + RL KTK E    D    KE RD +ER       +  +++EKE  ++K+   E + YS L  +  M SN+D
Sbjct:    1 MVFYFTSNVISPPYTMYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKDQTIEDIPKEVLLDCAQLVKANSIQGCKMNNINVVYTPWANLKKTADMDIGQIGFHRQKDVKTMTVEKV-SKIVNRLEKTKDERFP-DLAAEKEARDREERNEKKAQIQEIKRKEKEEMKKKKEMDELRSYSSLMKSENMSSNQD 198

[Close]

BLAST of CCD25 vs. UniProt/SwissProt
Match: sp|Q7T312|CCD25_DANRE (Coiled-coil domain-containing protein 25 OS=Danio rerio OX=7955 GN=ccdc25 PE=1 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 5.988e-72
Identity = 113/204 (55.39%), Postives = 149/204 (73.04%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVFYF S VV  P+TIYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI+ +P+ V+ DC QLVK NSIQGCK+NNI++VYT WSNLKKT DMD+GQ+GFH+ K V  + V+KK +E + RL KTK E+   D    KE RD +ER       + ++K+EKE  ++K+   + K+Y+ L  +  M +N+D  GY
Sbjct:    1 MVFYFTSAVVSPPHTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGTTIDDIPKEVLIDCVQLVKNNSIQGCKMNNINIVYTPWSNLKKTADMDIGQIGFHRQKEVKIVAVEKKINEIVNRLEKTK-EERYPDLAAEKESRDREERNEKKAQIQEQKKKEKEEVKKKKEMEDLKNYTSLMKSDNMTTNED--GY 201

[Close]

BLAST of CCD25 vs. UniProt/SwissProt
Match: sp|Q3SZX8|CCD25_BOVIN (Coiled-coil domain-containing protein 25 OS=Bos taurus OX=9913 GN=CCDC25 PE=2 SV=1)

HSP 1 Score: 216.468 bits (550), Expect = 7.099e-70
Identity = 113/201 (56.22%), Postives = 143/201 (71.14%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQGCK+NN++VVYT WSNLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D +  KE RD +ER       +  ++ EKE  ++K+   E + YS L     M SN+D
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLHKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKMERFP-DLEAEKECRDHEERNEKKAQIQEMKRREKEEMKKKREMDELRSYSSLMKVENMSSNQD 200

[Close]

BLAST of CCD25 vs. UniProt/SwissProt
Match: sp|Q78PG9|CCD25_MOUSE (Coiled-coil domain-containing protein 25 OS=Mus musculus OX=10090 GN=Ccdc25 PE=1 SV=1)

HSP 1 Score: 216.083 bits (549), Expect = 1.028e-69
Identity = 113/201 (56.22%), Postives = 142/201 (70.65%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLRL + E I  +P+ V+ DCA LVK NSIQGCK+NN++VVYT WSNLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER       +  +++EKE  ++K+   E + YS L     M SN+D
Sbjct:    1 MVFYFTSSSVNSSTYTIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRLQKGEKIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKLEKFP-DLAAEKEGRDREERNEKKAQIQEMKRKEKEEMKKKREMDELRSYSSLMKVENMSSNQD 200

[Close]

BLAST of CCD25 vs. UniProt/SwissProt
Match: sp|Q5R9S1|CCD25_PONAB (Coiled-coil domain-containing protein 25 OS=Pongo abelii OX=9601 GN=CCDC25 PE=2 SV=2)

HSP 1 Score: 214.542 bits (545), Expect = 4.528e-69
Identity = 113/201 (56.22%), Postives = 141/201 (70.15%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF S+ V  + YTIYMG+DK+ENEDLIK GWPED+WFHVDKLSSAHVYLRL++ E I  +P+ V+ DCA LVK NSIQGCK+NN++VVYT WSNLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER       +  ++ EKE  ++K+   E + YS L     M SN+D
Sbjct:    1 MVFYFTSSSVNSSAYTIYMGKDKYENEDLIKHGWPEDIWFHVDKLSSAHVYLRLHKGENIEDIPKEVLMDCAHLVKANSIQGCKMNNVNVVYTPWSNLKKTADMDVGQIGFHRQKDVKIVTVEKKVNEILNRLEKTKVERFP-DLAAEKECRDREERNEKKAQIQEMKRREKEEMKKKREMDELRSYSSLMKVENMSSNQD 200

[Close]

BLAST of CCD25 vs. TrEMBL
Match: A0A0B6ZWY3 (NFACT-R_1 domain-containing protein (Fragment) OS=Arion vulgaris OX=1028688 GN=ORF85347 PE=4 SV=1)

HSP 1 Score: 247.669 bits (631), Expect = 2.671e-79
Identity = 121/203 (59.61%), Postives = 156/203 (76.85%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAG 670
            MV +F SNVV  PYT++MG DKFENE+LI+WGWPEDVWFHVDKLSSAHVYLRL+  ETI+ VP++VI DCAQLVK NSIQG K NN++VVYT W+NLKKT  MDVGQVGFH+ K V  I+V+K+ +ET+ RLNKTK+E+   DF+ ++E RDSKER+     ++ +++ EKE  ++K  +AE + YS L  +  M +NKD  G
Sbjct:   21 MVLFFTSNVVVPPYTLFMGFDKFENEELIRWGWPEDVWFHVDKLSSAHVYLRLHPGETIDDVPQAVIDDCAQLVKANSIQGNKQNNLEVVYTMWNNLKKTQSMDVGQVGFHREKDVKKIKVEKRINETVNRLNKTKTEEDKPDFRALREARDSKERENQRRVQQEQKQREKEDEKRKLEQAEVRSYSGLMKSENMKTNKDFQG 223

[Close]

BLAST of CCD25 vs. TrEMBL
Match: A0A183AQ16 (NFACT-R_1 domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS9051 PE=4 SV=1)

HSP 1 Score: 243.432 bits (620), Expect = 5.281e-78
Identity = 120/204 (58.82%), Postives = 151/204 (74.02%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVFY+   +V  PY +YMG DK EN++LI+WGWPEDVWFHVDKLSSAHVYLRL E ET++ VP++VIQDCAQLVK+NSIQGCKLN++ VVYT W NLKKT DM VGQVGFH  K V  I V+K+  E IKRL KTK E    D + ++EERD + R +   A+  R+K E+E+ + ++ EAE + Y +LF  SKM +N+D  GY
Sbjct:    1 MVFYYKCELVHPPYILYMGADKNENDELIRWGWPEDVWFHVDKLSSAHVYLRLREGETLDDVPDAVIQDCAQLVKDNSIQGCKLNDVTVVYTMWENLKKTGDMAVGQVGFHNGKLVRKIVVEKRIGEVIKRLEKTKEERSAVDLRALREERDQQMRAKEKAAQSARKKAEREAQKLREAEAERRSYDRLFVESKMRTNED--GY 202

[Close]

BLAST of CCD25 vs. TrEMBL
Match: A0A4V3SGC5 (NFACT-R_1 domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_002433 PE=4 SV=1)

HSP 1 Score: 242.662 bits (618), Expect = 9.318e-78
Identity = 120/204 (58.82%), Postives = 152/204 (74.51%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVF++   +V   Y IYMG DK ENE+LI+WGWPEDVWFHVDKLSSAHVYLRL E ET++ VP++V++DCAQLVKENSIQGCKLN++ VVYT W NLKKT DM VGQVGFH  K+V  I V+K+  E IKRL KTK E L  D++  +EERD + R +   A+  R+K E+E+ + ++ EAE + Y +LF  SKM +N+D  GY
Sbjct:    1 MVFFYKCELVHPAYIIYMGADKNENEELIRWGWPEDVWFHVDKLSSAHVYLRLREGETLDDVPDAVLKDCAQLVKENSIQGCKLNDVTVVYTMWENLKKTGDMAVGQVGFHSGKAVRKITVEKRIGEVIKRLEKTKEERLNFDYRAEREERDQRMRAKEKAAQTARKKAEREAQKIREAEAERRSYDRLFVESKMRTNED--GY 202

[Close]

BLAST of CCD25 vs. TrEMBL
Match: G7YEW3 (Coiled-coil domain-containing protein 25 (Fragment) OS=Clonorchis sinensis OX=79923 GN=CLF_106259 PE=4 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 1.196e-77
Identity = 120/204 (58.82%), Postives = 152/204 (74.51%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVF++   +V   Y IYMG DK ENE+LI+WGWPEDVWFHVDKLSSAHVYLRL E ET++ VP++V++DCAQLVKENSIQGCKLN++ VVYT W NLKKT DM VGQVGFH  K+V  I V+K+  E IKRL KTK E L  D++  +EERD + R +   A+  R+K E+E+ + ++ EAE + Y +LF  SKM +N+D  GY
Sbjct:    1 MVFFYKCELVHPAYIIYMGADKNENEELIRWGWPEDVWFHVDKLSSAHVYLRLREGETLDDVPDAVLKDCAQLVKENSIQGCKLNDVTVVYTMWENLKKTGDMAVGQVGFHSGKAVRKITVEKRIGEIIKRLEKTKEERLNFDYRAEREERDQRIRAKEKAAQTARKKAEREAQKIREAEAERRSYDRLFVESKMRTNED--GY 202

[Close]

BLAST of CCD25 vs. TrEMBL
Match: A0A075AE16 (NFACT-R_1 domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_06305 PE=4 SV=1)

HSP 1 Score: 242.276 bits (617), Expect = 1.834e-77
Identity = 120/204 (58.82%), Postives = 152/204 (74.51%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MVF++   +V   Y IYMG DK ENE+LI+WGWPEDVWFHVDKLSSAHVYLRL E ET++ VP++V++DCAQLVKENSIQGCKLN++ VVYT W NLKKT DM VGQVGFH  K+V  I V+K+  E IKRL KTK E L  D++  +EERD + R +   A+  R+K E+E+ + ++ EAE + Y +LF  SKM +N+D  GY
Sbjct:    1 MVFFYKCELVHPAYIIYMGADKNENEELIRWGWPEDVWFHVDKLSSAHVYLRLREGETLDDVPDAVLKDCAQLVKENSIQGCKLNDVTVVYTMWENLKKTGDMAVGQVGFHSGKAVRKITVEKRIGEVIKRLEKTKEERLNFDYRAEREERDQRIRAKEKAAQTARKKAEREAQKIREAEAERRSYDRLFVESKMRTNED--GY 202

[Close]

BLAST of CCD25 vs. Ensembl Cavefish
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:393359])

HSP 1 Score: 223.016 bits (567), Expect = 5.702e-73
Identity = 113/202 (55.94%), Postives = 147/202 (72.77%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMA 667
            MVFYF S VV  PY IYMG+DK+ENEDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI  +P+ V+ DCAQLVK NSIQGCK+NNI+VVYT WSNLKKT DMDVGQ+GF++ K V T+ V+KK +E + RL KTK E+   D    KE RD +ER       +  +K+EKE  ++K+ + + + YS L  +  M +N+ ++
Sbjct:    1 MVFYFTSAVVSPPYIIYMGKDKYENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGSTIEDIPKEVLIDCAQLVKNNSIQGCKMNNINVVYTPWSNLKKTGDMDVGQIGFYRQKEVKTVAVEKKINEIVNRLEKTK-EERYPDLAAEKESRDREERNEKKAQVQETKKKEKEEMKRKKEQEDLRSYSSLMKSDNMTTNEVLS 201

[Close]

BLAST of CCD25 vs. Ensembl Sea Lamprey
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:393359])

HSP 1 Score: 220.705 bits (561), Expect = 3.263e-73
Identity = 116/200 (58.00%), Postives = 148/200 (74.00%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKD 661
            MVFYF+SNV  TPYTIY+G+DK+ENE+LIK+GWPEDVWFHVDKLSSAHVYLRL + +T++ +P  V+ DCAQLVK NSIQG K+NNI VVYT W NLKKT DMDVGQVGFHK K V T+ V+K+ +E + RLN+T+ E L  D    +E+RD +ER       + +++ EKE  R+K+ + E + YS L     M SN+D
Sbjct:    1 MVFYFVSNVGSTPYTIYVGKDKYENEELIKYGWPEDVWFHVDKLSSAHVYLRLQKGQTMDDIPTEVLIDCAQLVKANSIQGNKMNNIAVVYTPWGNLKKTADMDVGQVGFHKQKEVRTVTVEKRVNEIMNRLNRTRDERLP-DLASEREDRDREERGEKKAQLQEQKRNEKEETRRKREQEELRSYSALMKEENMTSNQD 199

[Close]

BLAST of CCD25 vs. Ensembl Yeast
Match: JLP2 (Protein of unknown function; contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein) [Source:SGD;Acc:S000004739])

HSP 1 Score: 123.25 bits (308), Expect = 2.519e-35
Identity = 64/143 (44.76%), Postives = 88/143 (61.54%), Query Frame = 2

Query:   62 MVFYFISNVVE--TPYTIYMGRDKFENEDLIKWGWPE--DVWFHVDKLSSAHVYLRLNENE-TINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSE 475
            MV+++ S   E  TPY I MG+DKFEN+ LIKW + E   VWFH DK SS HVYL+L  NE TI+ +P+ VI DC QL K  SIQG K+    ++ T W NL+K   M+ G+V F   +    +    ++++ + RL KT+ E
Sbjct:    1 MVYFYESKPTEYSTPYQIVMGKDKFENDLLIKWSYRELNYVWFHADKYSSGHVYLKLRPNEKTIDDIPQEVICDCLQLCKSESIQGNKMPQCTILITPWHNLRKNRYMNPGEVSFKSLRQCRKMECGARDNKILNRLAKTRVE 143

[Close]

BLAST of CCD25 vs. Ensembl Nematostella
Match: EDO37379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SG12])

HSP 1 Score: 191.815 bits (486), Expect = 1.317e-61
Identity = 92/139 (66.19%), Postives = 108/139 (77.70%), Query Frame = 2

Query:   62 MVFYFISNVV-ETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSE 475
            MVFYF SN      YT+YMG DK ENE+LIKWG+PEDVWFHVDKLSSAHVYLRL + +T + +P  V+ DCAQLVK NSIQG K+NNI +VYT WSNLKKT DM+VGQVGF+ +K V  I V K+ +E + RLNKTK E
Sbjct:    1 MVFYFTSNAAFPAIYTLYMGLDKHENEELIKWGFPEDVWFHVDKLSSAHVYLRLPKGKTWDDIPPEVLDDCAQLVKANSIQGNKMNNIKIVYTPWSNLKKTADMEVGQVGFYNDKQVRLIPVVKRRNEAVNRLNKTKEE 139

[Close]

BLAST of CCD25 vs. Ensembl Medaka
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:101156713])

HSP 1 Score: 230.335 bits (586), Expect = 5.335e-74
Identity = 103/156 (66.03%), Postives = 122/156 (78.21%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKER 529
            MVFYF S VV+ P+TIYMG+DK ENEDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI+ VP  V+ DCAQLVK NSIQGCK+NNI+VVYT W+NLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER
Sbjct:    1 MVFYFTSAVVDPPFTIYMGKDKHENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGGTIDDVPPEVLVDCAQLVKNNSIQGCKMNNINVVYTPWANLKKTGDMDVGQIGFHRQKEVRVVAVEKKINEIVNRLEKTKVERFP-DLAAEKESRDREER 155

[Close]

BLAST of CCD25 vs. Ensembl Medaka
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:101156713])

HSP 1 Score: 190.66 bits (483), Expect = 3.552e-58
Identity = 86/133 (64.66%), Postives = 103/133 (77.44%), Query Frame = 2

Query:  131 ENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKER 529
            E+EDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI+ VP  V+ DCAQLVK NSIQGCK+NNI+VVYT W+NLKKT DMDVGQ+GFH+ K V  + V+KK +E + RL KTK E    D    KE RD +ER
Sbjct:   60 EDEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGGTIDDVPPEVLVDCAQLVKNNSIQGCKMNNINVVYTPWANLKKTGDMDVGQIGFHRQKEVRVVAVEKKINEIVNRLEKTKVERFP-DLAAEKESRDREER 191

[Close]

BLAST of CCD25 vs. Ensembl Medaka
Match: ccdc25 (coiled-coil domain containing 25 [Source:NCBI gene;Acc:101156713])

HSP 1 Score: 151.369 bits (381), Expect = 3.406e-45
Identity = 82/156 (52.56%), Postives = 100/156 (64.10%), Query Frame = 2

Query:   62 MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKER 529
            MVFYF S VV+ P+TIYMG+DK ENEDLIK+GWPED+WFHVDKLSSAHVYLR+ +  TI+ VP  V+ DCAQLVK NSIQG    +    +T      K      G+ G     +V  + V+KK +E + RL KTK E    D    KE RD +ER
Sbjct:    1 MVFYFTSAVVDPPFTIYMGKDKHENEDLIKYGWPEDIWFHVDKLSSAHVYLRMPKGGTIDDVPPEVLVDCAQLVKNNSIQGESRGSAGSGWT------KRGTWMWGRSG----STVRVVAVEKKINEIVNRLEKTKVERFP-DLAAEKESRDREER 145

[Close]

BLAST of CCD25 vs. Planmine SMEST
Match: SMESG000046670.1 (SMESG000046670.1)

HSP 1 Score: 356.295 bits (913), Expect = 2.383e-126
Identity = 187/187 (100.00%), Postives = 187/187 (100.00%), Query Frame = 2

Query:  113 MGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHXXXXXXXXXXXXSNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 673
            MGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHEAERLRRKEEKESNRQKQIEAESKDYSKLFDTSKMISNKDMAGY
Sbjct:    1 MGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVYLRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKTNDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEERDSKERKRSHEAERLRRKEEKESNRQKQIEAESKDYSKLFDTSKMISNKDMAGY 187

The following BLAST results are available for this feature:

BLAST of CCD25 vs. Ensembl Human
BLAST of CCD25 vs. Ensembl Celegans
BLAST of CCD25 vs. Ensembl Fly
BLAST of CCD25 vs. Ensembl Zebrafish
BLAST of CCD25 vs. Ensembl Xenopus
BLAST of CCD25 vs. Ensembl Mouse
BLAST of CCD25 vs. UniProt/SwissProt
BLAST of CCD25 vs. TrEMBL
BLAST of CCD25 vs. Ensembl Cavefish
BLAST of CCD25 vs. Ensembl Sea Lamprey
BLAST of CCD25 vs. Ensembl Yeast
BLAST of CCD25 vs. Ensembl Nematostella
BLAST of CCD25 vs. Ensembl Medaka
BLAST of CCD25 vs. Planmine SMEST

BLAST of CCD25 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CCDC25	9.429e-70	56.72	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]
CCDC25	7.289e-38	69.88	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]
CCDC25	7.289e-38	69.88	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]
CCDC25	9.483e-38	70.73	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]
CCDC25	9.483e-38	70.73	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]

BLAST of CCD25 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2


Match Name	E-value	Identity	Description
Y54G11A.2	4.930e-65	61.39	pep chromosome:WBcel235:II:14252357:14255705:1 gen...	[more]
F43C1.7	3.826e-40	49.61	pep chromosome:WBcel235:III:4241477:4242593:-1 gen...	[more]

BLAST of CCD25 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
CG4593	1.741e-73	53.96	gene:FBgn0029929 transcript:FBtr0343331	[more]
CG4593	1.741e-73	53.96	gene:FBgn0029929 transcript:FBtr0071009	[more]

BLAST of CCD25 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ccdc25	7.932e-73	55.39	coiled-coil domain containing 25 [Source:NCBI gene...	[more]

BLAST of CCD25 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1


Match Name	E-value	Identity	Description
CCDC25	2.915e-38	70.13	coiled-coil domain containing 25 [Source:HGNC Symb...	[more]

BLAST of CCD25 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Ccdc25	1.470e-70	56.22	coiled-coil domain containing 25 [Source:MGI Symbo...	[more]

BLAST of CCD25 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q6GLE1\|CCD25_XENTR	5.260e-73	57.00	Coiled-coil domain-containing protein 25 OS=Xenopu...	[more]
sp\|Q7T312\|CCD25_DANRE	5.988e-72	55.39	Coiled-coil domain-containing protein 25 OS=Danio ...	[more]
sp\|Q3SZX8\|CCD25_BOVIN	7.099e-70	56.22	Coiled-coil domain-containing protein 25 OS=Bos ta...	[more]
sp\|Q78PG9\|CCD25_MOUSE	1.028e-69	56.22	Coiled-coil domain-containing protein 25 OS=Mus mu...	[more]
sp\|Q5R9S1\|CCD25_PONAB	4.528e-69	56.22	Coiled-coil domain-containing protein 25 OS=Pongo ...	[more]

BLAST of CCD25 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A0B6ZWY3	2.671e-79	59.61	NFACT-R_1 domain-containing protein (Fragment) OS=...	[more]
A0A183AQ16	5.281e-78	58.82	NFACT-R_1 domain-containing protein OS=Echinostoma...	[more]
A0A4V3SGC5	9.318e-78	58.82	NFACT-R_1 domain-containing protein OS=Opisthorchi...	[more]
G7YEW3	1.196e-77	58.82	Coiled-coil domain-containing protein 25 (Fragment...	[more]
A0A075AE16	1.834e-77	58.82	NFACT-R_1 domain-containing protein OS=Opisthorchi...	[more]

BLAST of CCD25 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ccdc25	5.702e-73	55.94	coiled-coil domain containing 25 [Source:NCBI gene...	[more]

BLAST of CCD25 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ccdc25	3.263e-73	58.00	coiled-coil domain containing 25 [Source:NCBI gene...	[more]

BLAST of CCD25 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1


Match Name	E-value	Identity	Description
JLP2	2.519e-35	44.76	Protein of unknown function; contains sequence tha...	[more]

BLAST of CCD25 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO37379	1.317e-61	66.19	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of CCD25 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ccdc25	5.335e-74	66.03	coiled-coil domain containing 25 [Source:NCBI gene...	[more]
ccdc25	3.552e-58	64.66	coiled-coil domain containing 25 [Source:NCBI gene...	[more]
ccdc25	3.406e-45	52.56	coiled-coil domain containing 25 [Source:NCBI gene...	[more]

BLAST of CCD25 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000046670.1	2.383e-126	100.00	SMESG000046670.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024991 ID=SMED30024991|Name=CCD25|organism=Schmidtea mediterranea sexual|type=transcript|length=737bp
TTGAAATATATTATCGATTGATTTGTTTTAATATTCAATATACAAACTGA
CGTTTGAAATCATGGTATTTTATTTTATAAGTAATGTTGTTGAAACTCCT
TATACAATTTATATGGGAAGAGATAAATTTGAAAATGAAGATTTAATTAA
ATGGGGATGGCCAGAAGATGTATGGTTTCATGTTGATAAATTAAGTTCAG
CCCATGTTTATCTTCGATTAAATGAAAATGAAACCATTAACAGTGTTCCA
GAATCTGTAATTCAGGATTGTGCTCAATTAGTCAAAGAAAATAGTATTCA
GGGATGTAAGTTGAATAATATAGATGTGGTTTATACATCTTGGTCTAATT
TAAAAAAGACTAATGACATGGATGTTGGTCAAGTAGGATTTCATAAAAAT
AAGAGTGTTATGACTATCCGAGTTGATAAGAAAAATAGTGAAACTATTAA
ACGCTTGAATAAAACAAAATCTGAAGACCTTACTCAAGACTTCAAATTAA
TAAAAGAAGAAAGAGATTCCAAAGAACGTAAAAGATCGCATGAAGCTGAA
CGATTGAGAAGGAAGGAAGAAAAAGAATCAAATAGACAAAAGCAGATTGA
AGCAGAATCAAAAGACTATAGCAAATTGTTCGATACTTCAAAAATGATAA
GCAATAAGGACATGGCGGGCTATGATTCTGATGACTTTTTTAGTTGATTT
TAAATACCAATAAATTATTTTTAACATAATTGTTGAT

protein sequence of SMED30024991-orf-1

>SMED30024991-orf-1 ID=SMED30024991-orf-1|Name=SMED30024991-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=212bp
MVFYFISNVVETPYTIYMGRDKFENEDLIKWGWPEDVWFHVDKLSSAHVY
LRLNENETINSVPESVIQDCAQLVKENSIQGCKLNNIDVVYTSWSNLKKT
NDMDVGQVGFHKNKSVMTIRVDKKNSETIKRLNKTKSEDLTQDFKLIKEE
RDSKERKRSHEAERLRRKEEKESNRQKQIEAESKDYSKLFDTSKMISNKD
MAGYDSDDFFS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0005575	cellular_component

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000429	neoblast
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR039730	Jlp2/Ccd25
IPR008532	NFACT_RNA-bd

Vocabulary: **molecular function**
Term	Definition
GO:0003674	molecular_function

Vocabulary: **biological process**
Term	Definition
GO:0008150	biological_process

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 162..182
None	No IPR available	COILS	Coil	Coil	coord: 137..157
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 150..184
None	No IPR available	PANTHER	PTHR13049:SF2	COILED-COIL DOMAIN-CONTAINING PROTEIN 25	coord: 1..209
IPR008532	NFACT, RNA-binding domain	PFAM	PF05670	NFACT-R_1	coord: 1..111 e-value: 1.7E-44 score: 150.9
IPR039730	Jlp2/Ccd25	PANTHER	PTHR13049	DUF814-RELATED	coord: 1..209