3-hydroxybutyrate dehydrogenase, type 1

Overview


Name	3-hydroxybutyrate dehydrogenase, type 1
Smed ID	SMED30024934
Length (bp)	1272

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of 3-hydroxybutyrate dehydrogenase, type 1 (SMED30024934) t-SNE clustered cells

Violin plots show distribution of expression levels for 3-hydroxybutyrate dehydrogenase, type 1 (SMED30024934) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of 3-hydroxybutyrate dehydrogenase, type 1 (SMED30024934) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for 3-hydroxybutyrate dehydrogenase, type 1 (SMED30024934) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024934

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 9

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v4_8012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v4_8012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v4_8012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v4_8012_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1 SMESG000065255.1 SMESG000050057.1	OX_Smed_1.0.02541	ox_Smed_v2	PMID:24238224 Kao et al., 2013
gut	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	SMED30024934	smed_20140614	PMID:26457503 Tu et al., 2015
parenchyma	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	SMED30024934	smed_20140614	PMID:26457503 Tu et al., 2015
Category 3 cell	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v6_8012_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
Category 3 cell	SMED30024934	SMESG000039796.1 SMESG000039794.1 SMESG000039792.1	dd_Smed_v4_8012_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Human
Match: SDR9C7 (short chain dehydrogenase/reductase family 9C member 7 [Source:HGNC Symbol;Acc:HGNC:29958])

HSP 1 Score: 154.066 bits (388), Expect = 1.015e-42
Identity = 98/259 (37.84%), Postives = 145/259 (55.98%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK--MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTN---------KVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKP 982
            K V +TGCDSGFG +LA+ L  RGM V A       EG+  L+ ++  ++    +DVTK E ++     VR  + +    LWA+VNNAGVG  S   E+L  D   +++ VN +GL+ V    LP++ R  GR+VN++S SG  V+   GGYC SKF  EA SD++R EL+  G+ V  I P  Y+T IL   N         +    E    YGE + +   D L+N ++ A    ++VIN++E AI++R+ + +Y P
Sbjct:   26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFT--EEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQG--LWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSS-SGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNP 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Human
Match: BDH1 (3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Symbol;Acc:HGNC:1027])

HSP 1 Score: 149.058 bits (375), Expect = 1.291e-40
Identity = 94/288 (32.64%), Postives = 157/288 (54.51%), Query Frame = 2

Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +     V + +S+    ++ ++++V   EEVE+ + IVR +L D +  +W +VNNAG+     +EF  ++  +Q+ EVN  G +R+ + FLPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E++PLG+ V  + P  +     L + +       K+           YG+K+  +    +  +  S S +   VI+A+  A+   T   +Y P   +   RM+I+     ++++ I
Sbjct:   53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMI 340

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Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +     V + +S+    ++ ++++V   EEVE+ + IVR +L D +  +W +VNNAG+     +EF  ++  +Q+ EVN  G +R+ + FLPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E++PLG+ V  + P  +     L + +       K+           YG+K+  +    +  +  S S +   VI+A+  A+   T   +Y P   +   RM+I+     ++++ I
Sbjct:   53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMI 340

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Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +     V + +S+    ++ ++++V   EEVE+ + IVR +L D +  +W +VNNAG+     +EF  ++  +Q+ EVN  G +R+ + FLPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E++PLG+ V  + P  +     L + +       K+           YG+K+  +    +  +  S S +   VI+A+  A+   T   +Y P   +   RM+I+     ++++ I
Sbjct:   53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMI 340

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Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +     V + +S+    ++ ++++V   EEVE+ + IVR +L D +  +W +VNNAG+     +EF  ++  +Q+ EVN  G +R+ + FLPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E++PLG+ V  + P  +     L + +       K+           YG+K+  +    +  +  S S +   VI+A+  A+   T   +Y P   +   RM+I+     ++++ I
Sbjct:   53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMI 340

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
Match: dhs-20 (DeHydrogenases, Short chain [Source:UniProtKB/TrEMBL;Acc:Q20012])

HSP 1 Score: 127.487 bits (319), Expect = 4.430e-33
Identity = 73/194 (37.63%), Postives = 119/194 (61.34%), Query Frame = 2

Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV---VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMME-FLPIDKLRQLLEVNALGLLRVCQKFLPLLRG-HGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL 802
            ++++++L+TGCD+GFG  LA+  AK G  VFAG L   +E A  L+  S    ++ + +DV+KDE VE+ +  V+++L +  + LW VVNNAG+      + +  ++  +  L+VN LG++RV Q F  L++   GRIV +TS++G + +P  G Y  SKF A A  D +R EL+  G+ V  + P  ++T +L
Sbjct:   39 LQDRAILITGCDTGFGRELAKKCAKNGFLVFAGCLT--TEAAKTLESESANPRLRTVPLDVSKDESVEKTVEFVKKSLGN--HKLWGVVNNAGIFSCYGPDDWCRMNDYKLALDVNCLGVIRVTQAFKKLVKAAKGRIVTVTSVNGRLSTPAAGPYVVSKFGAAAYMDCIRQELYNFGVKVSILEPGIFRTPLL 228

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
Match: dhs-16 (3 beta-hydroxysteroid dehydrogenase dhs-16 [Source:UniProtKB/Swiss-Prot;Acc:O16881])

HSP 1 Score: 125.561 bits (314), Expect = 5.989e-32
Identity = 88/297 (29.63%), Postives = 144/297 (48.48%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFA------GVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMME-FLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL------LSTNKVFGT---EETKLYGEKFIKKSEDILRNWVESASV----NFQEVINALESAILNRTYQYKYKPNF--VFRMKILMMKANSLNNRIQTG 1051
            VE   K V++TGCDSGFG +LA SL  + + VFA      G+ +L+SE          +  +++DVT    V+     V + L + +  LW +VNNAG+      + +  +D+    L VN LG +R+C  F+PL++   GRIV + S +G +   ++  Y  +KF  EA  D LR E+ P G+ V  + P  +KT +L      +   K++ +   E  + YGE +     D  R W    +V    N   V++    A+ +   + +Y P +  +F    L +   +L + I  G
Sbjct:   28 VESSGKYVMITGCDSGFGRLLATSLLDKHVNVFAACFTQQGMASLHSEWKLKKGPKGQLYTLQLDVTSQASVDSAKSFVTKILKEQNSKLWGLVNNAGIFSIHGPDDWCSVDEYASSLNVNTLGAVRMCHAFVPLIKKSRGRIVTMGSTAGRLHGLYVAPYVTAKFAVEAYMDCLRLEMRPFGVSVHILEPGCFKTELLNNDAQRMRIQKIWNSLSVETKEEYGEDY---RNDFERAWEAGVNVVANPNIGWVVDCYSHALFSWWPRLRYCPGWDAIFMFIPLSIFPTALQDWILAG 321

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
Match: drd-5 (Dietary restriction down regulated [Source:UniProtKB/TrEMBL;Acc:Q20840])

HSP 1 Score: 112.849 bits (281), Expect = 7.502e-28
Identity = 85/270 (31.48%), Postives = 138/270 (51.11%), Query Frame = 2

Query:  212 YEDLHKVEVKN---KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK---MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL-LSTNKV------FGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            Y  L K  V N   K+V ++GCDSGFG +LA  L K+G+ V AGVL     G S+ K  +   ++    ++V  DE V+E + +V +T+ +    LW VV NAG+ G+S   ++L        ++VN  G++R  Q     ++   GR+V ++SISG    P +G YC SK   EA +D +R EL    + V  + P  + T I   +TN +         E  K YG++F    ++   + +   + +   VI+A + A+L +  + +Y
Sbjct:   23 YNFLIKQRVDNYGKKTVAISGCDSGFGRLLAVRLVKQGVPVIAGVLK-KENGESLKKEVNTPSLLTFGILNVANDESVKEFVKLVEKTVENRG--LWGVVANAGILGNSGPDDWLSAQDYINTMQVNTFGVMRFIQGLKKFVKKQEGRVVIISSISGRTPRPTVGPYCVSKHAVEAYADVIRHELIDFNVSVHLLEPGFFTTNITQTATNDLDAVWERLDDETKKEYGKEFYDDYKNSRFSRLSHCADDLNPVIDAYDHALLGKYPKTRY 289

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Query:  212 YEDLHKVEVKN---KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK---MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL-LSTNKV------FGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            Y  L K  V N   K+V ++GCDSGFG +LA  L K+G+ V AGVL     G S+ K  +   ++    ++V  DE V+E + +V +T+ +    LW VV NAG+ G+S   ++L        ++VN  G++R  Q     ++   GR+V ++SISG    P +G YC SK   EA +D +R EL    + V  + P  + T I   +TN +         E  K YG++F    ++   + +   + +   VI+A + A+L +  + +Y
Sbjct:   23 YNFLIKQRVDNYGKKTVAISGCDSGFGRLLAVRLVKQGVPVIAGVLK-KENGESLKKEVNTPSLLTFGILNVANDESVKEFVKLVEKTVENRG--LWGVVANAGILGNSGPDDWLSAQDYINTMQVNTFGVMRFIQGLKKFVKKQEGRVVIISSISGRTPRPTVGPYCVSKHAVEAYADVIRHELIDFNVSVHLLEPGFFTTNITQTATNDLDAVWERLDDETKKEYGKEFYDDYKNSRFSRLSHCADDLNPVIDAYDHALLGKYPKTRY 289

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
Match: dhs-2 (DeHydrogenases, Short chain [Source:UniProtKB/TrEMBL;Acc:Q86NJ7])

HSP 1 Score: 108.997 bits (271), Expect = 2.418e-26
Identity = 88/279 (31.54%), Postives = 134/279 (48.03%), Query Frame = 2

Query:  209 FYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVL------NLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYI--LWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI---------LLSTNKVFGTEETKLYGEKFI---KKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYK 979
            F E L    +  ++V +TGCDSGFG  LA    ++GM VFAG L      +L++E    +     +    MDVT DE V E   + ++     +    L AVVNNAG+ G     +FL I++  ++  +N  G +R       LL+   GR+V + SI   V  P LG Y  SK+   A  D +R EL P GI V  + P  + T +         +L   K    E  + YGEKF    ++S  +  N V S+ ++   V++A   AI ++  + +Y+
Sbjct:   33 FIEKLQINNLSKRAVFITGCDSGFGRGLALKCLEQGMPVFAGCLTEQGIESLSAEARKSIGNGRSLDAFLMDVTSDESVGE---VAKRLEKKCEQYGGLHAVVNNAGITGKHIADDFLDINEYLKVANINLWGPIRTTMAVKKLLKKARGRVVTVASICARVGLPGLGPYSVSKYGVSAYCDVIRQELRPFGISVHVLEPGFFNTPLINREKIDAEILEAWKHAPNEVKQEYGEKFFNDARESTHLFLNSVASSQISL--VVDAYFHAITSKHPRSRYQ 306

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Match: CG8888 (gene:FBgn0033679 transcript:FBtr0088022)

HSP 1 Score: 101.293 bits (251), Expect = 2.511e-23
Identity = 83/292 (28.42%), Postives = 139/292 (47.60%), Query Frame = 2

Query:  161 AIIGLIVWIILSELQ--LFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNL--NSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY--------KTYILLSTNKVF---GTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKP 982
            +   + VW  L+ +   LFY  + KV    K VL+TGC++     LA+ L   G  V+AG       S+ A +LK   +  +K++ +DVT ++ + E    V Q L      LW+VV+ A       +E++P   LR+ L++N LG  R+ Q FLPL+R  HGR+V LTS    V SP  G  CA++   +  +  LR E+   G+ V  +    +        +T +     +++    +E+ K YGE + + +   +  +   A+ + Q  +  L  A+       +Y P
Sbjct:   67 STFAVFVWFALATVGAVLFYHFV-KVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTSVEKYSRQAA-DIQPTLRVLIDAVTRTFPMARYTP 356

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Match: sro (gene:FBgn0262112 transcript:FBtr0085481)

HSP 1 Score: 86.6557 bits (213), Expect = 1.525e-18
Identity = 65/192 (33.85%), Postives = 99/192 (51.56%), Query Frame = 2

Query:  251 VLVTGCDSGFGLMLA----QSLAKRGMFVFAGVLNLNSEGASVLKFNSVVK-------VIKMDVTKDEEVEEGLCIVRQTLT-DMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY 787
            VL+TGCDSG G  +A    +SL    M V +   N+ SEGA +L+  +  K        +++D+ + + +      +R  L  D  Y L A++NNAGV      E+   +++   +  N LG +R+  + LPLLR   GRI+N+TS  G    P LG Y ASK      +D+LR EL   G+ V+   P ++
Sbjct:   29 VLITGCDSGLGHSMAVYCHESLH---MTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLELDLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLGTMRLTHELLPLLRQQQGRIINVTSHCGLQALPALGPYAASKAALRFWTDSLRVELQQYGMEVVNFIPGSF 217

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Match: CG3699 (gene:FBgn0040349 transcript:FBtr0070186)

HSP 1 Score: 76.6406 bits (187), Expect = 1.417e-15
Identity = 64/186 (34.41%), Postives = 99/186 (53.23%), Query Frame = 2

Query:  242 NKSVLVTGCDSGFGLMLAQSLAKRG---MFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLP-LLRGHGRIVNLTSISGEVVSPFLGG--YCASKFCAEAISDALRFELHPLGIPVITINP 778
            NK V+VTG  SG G  +AQ LA+ G     V   V NL +   S LK  +  +++  DVTKD +      IV+QTL     I   +VNNAG+ G   +++ L I++   +L  N  G++ + +  LP LL+  G +VN++S +G  + PF G   Y  SK   +  +  +  E+ P G+ V ++NP
Sbjct:    5 NKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKS-LK-GTQAEIVVADVTKDAD-----AIVQQTLAKFGRI-DVLVNNAGILGKGGLID-LDIEEFDAVLNTNLRGVILLTKAVLPHLLKTKGAVVNVSSCAG--IRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNP 179

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Match: CG13377 (gene:FBgn0261446 transcript:FBtr0332990)

HSP 1 Score: 75.0998 bits (183), Expect = 1.201e-14
Identity = 62/234 (26.50%), Postives = 111/234 (47.44%), Query Frame = 2

Query:  128 LPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNL-NSEGASVL------------KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLG----GYCASKFCAEAISDALRFELHPLGIPVITIN 775
            L LGF  L L +I G ++  ++ +++      +     ++ VL+T  D+  GL L   LA +G  VFAG+    +S  A +L                 +  +++DVT+++ + E   I+   L   +  + AV+N +G      +E   + +   +L  N LG LRV + F+  LR   GR++ L  +SG   +   G     + AS+   +  ++ LR ELHP G+ V+ ++
Sbjct:    7 LVLGFQLLALFSIAGALLIYLICKVREDSASANADSHPSRVVLITSADTALGLQLCTHLANKGYRVFAGMKEAQDSLPAKLLCGWMKIREYSEEPIAGTIIPMRLDVTREDVLREATVIIGANLNADERGIAAVINTSGSVFRGQVESQNVQQWEHMLRTNILGTLRVAKAFVCFLRPTRGRLLYLGGVSGGGNARNEGDGLVAFNASRVAVDKCAEELRKELHPYGVSVVALD 240

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Match: CG13377 (gene:FBgn0261446 transcript:FBtr0070106)

HSP 1 Score: 75.0998 bits (183), Expect = 1.201e-14
Identity = 62/234 (26.50%), Postives = 111/234 (47.44%), Query Frame = 2

Query:  128 LPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNL-NSEGASVL------------KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLG----GYCASKFCAEAISDALRFELHPLGIPVITIN 775
            L LGF  L L +I G ++  ++ +++      +     ++ VL+T  D+  GL L   LA +G  VFAG+    +S  A +L                 +  +++DVT+++ + E   I+   L   +  + AV+N +G      +E   + +   +L  N LG LRV + F+  LR   GR++ L  +SG   +   G     + AS+   +  ++ LR ELHP G+ V+ ++
Sbjct:    7 LVLGFQLLALFSIAGALLIYLICKVREDSASANADSHPSRVVLITSADTALGLQLCTHLANKGYRVFAGMKEAQDSLPAKLLCGWMKIREYSEEPIAGTIIPMRLDVTREDVLREATVIIGANLNADERGIAAVINTSGSVFRGQVESQNVQQWEHMLRTNILGTLRVAKAFVCFLRPTRGRLLYLGGVSGGGNARNEGDGLVAFNASRVAVDKCAEELRKELHPYGVSVVALD 240

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
Match: bdh1 (3-hydroxybutyrate dehydrogenase, type 1 [Source:ZFIN;Acc:ZDB-GENE-070410-130])

HSP 1 Score: 163.696 bits (413), Expect = 4.251e-46
Identity = 94/288 (32.64%), Postives = 159/288 (55.21%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY---KPNFVFRMKILMMKANSLNNRI 1042
            V+V+ K++L+TGCD+GFGL LA+   K G  VFAG L  + EGA  L+   +  +KV+ +DV  +E+V + +  V + L D +  LW VVNNAG+     +EF  +D  +Q+ EVN  G +RV + FLPL+ R  GR+VN+ S+ G + +     YC SK+  EA SD LR+E+   G+ V  I P  +     + T  +  T   KL           YG+   ++   ++R++  S     + V++ +  AI+++    +Y   +P++  R++I+     ++++R+
Sbjct:   74 VKVEGKALLITGCDTGFGLALAKHFHKLGFTVFAGCLFKDGEGAKELENIHSEKLKVVPLDVCSEEQVSQAVQFVTENLPDSEKGLWGVVNNAGISTFGEVEFTTMDTYKQVSEVNLWGTIRVTKAFLPLIRRAKGRVVNIASMYGRMGNALRSPYCISKYGVEAFSDCLRYEMKTWGVKVSVIEPGNFIVATGILTRDIVTTTAEKLWKEAPPIVQEDYGKAHFEQYMALMRSYCNSGQREIEPVLDDITDAIMSQRPYTRYSPMEPHWWIRVQIMTHLPGAISDRL 361

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
Match: hsd17b2 (hydroxysteroid (17-beta) dehydrogenase 2 [Source:ZFIN;Acc:ZDB-GENE-040928-1])

HSP 1 Score: 133.265 bits (334), Expect = 7.742e-35
Identity = 94/259 (36.29%), Postives = 143/259 (55.21%), Query Frame = 2

Query:  257 VTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVK--VIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLG--GYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPN 985
            V  CDSGFG  LAQ L + GM VFAGVL+  S GA  LK ++ V   V+++D+T + ++ +    ++         LWA+VNNAGV G+    E LP+   +  L+VN LG + +   FLPL+R   GR++N+TS++GEV  P +G  GY ASK      S A+R EL   G+ VI + P A++T IL S+ +    +E  L          YGE++I   +  L +   ++S +    + +L+ AIL+   ++ Y P 
Sbjct:   63 VFSCDSGFGHELAQVLDRAGMRVFAGVLDELSPGALKLKESASVNLTVLQLDITNNTQITQTHQFIKSQTGKTG--LWALVNNAGVLGYVCDGEILPMKMYKSCLDVNFLGSVMMTHTFLPLIRHSRGRVINITSMAGEV--PLVGFAGYGASKAALNIYSGAIRQELSRWGVRVIIVQPGAFRTNILGSSEQWERAQEQILSGLSEEVKDSYGEEYIHSMQKRLLDMSSASSEDKGPFLQSLKHAILSSNPKHFYYPG 317

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
Match: hsd11b2 (hydroxysteroid (11-beta) dehydrogenase 2 [Source:ZFIN;Acc:ZDB-GENE-030131-6030])

HSP 1 Score: 132.494 bits (332), Expect = 4.729e-34
Identity = 99/317 (31.23%), Postives = 154/317 (48.58%), Query Frame = 2

Query:  110 WFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLH-KVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAG----VGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKK--------------------SEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            W     L     +L + A++  +V  +   L   +      + V++K+V +TGCDSGFG   A+ L   G  VFA VLNL  EGA  L+   +S + ++++D+T+ ++V++ L   +  L   D  LW +VNNAG    +G +++     +   R  +EVN  G + V + FLPLLR   GRIV ++S SGE   P L  Y ASK       + LR EL P G+ V TI P AYKT          G      Y EK  K                     ++++ +N+ ++A+ +   VI+ +  A+L+   Q +Y
Sbjct:   40 WLGATLLVERLCALCMPAVLARLVLCVCCWLYFTWATPKPSLPVEDKAVFITGCDSGFGNATAKKLDAMGFEVFATVLNLEGEGAKHLRKVCSSRLTLLQVDITQPQQVQQALLDTKAKLGIRD--LWGLVNNAGWCVNIGDAELSL---MSNYRGCMEVNFFGTVTVTRTFLPLLRQSKGRIVTISSPSGEHPFPCLASYGASKAALNLFINTLRHELDPWGVKVSTILPSAYKT----------GQSSNAEYWEKQYKSLLQGLSPNLLEEYGEEYLLETKELFQNYAKTANEDLSPVIDTIVEALLSPQPQVRY 341

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
Match: rdh5 (retinol dehydrogenase 5 (11-cis/9-cis) [Source:ZFIN;Acc:ZDB-GENE-050208-411])

HSP 1 Score: 125.561 bits (314), Expect = 2.761e-32
Identity = 99/301 (32.89%), Postives = 147/301 (48.84%), Query Frame = 2

Query:  140 FLSLVLGAIIGLIVWIILSELQLFYEDLHKV-EVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAG----VGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI---------LLSTNKVFGTEETKLYGEKFIKKSEDILRNWVES-ASVNFQEVINALESAILNRTYQYKYKPNF 988
            FLS    +   L  + IL  L  FY D  K+  V  K V VTGCDSGFG +L + L KRG  V AG   L  +GA  LK      +K   +DVT    +++ +   ++ + D    LW +VNNAG    +G S+ M+   I+     L+VN  G++     FLPL+ +  GR+VN+ S+ G V +   GGYC SKF  E+ SD LR ++   G+ V  I P  +KT +         L         E  + YG+K++ K   I R  + +    +  +V N +E A+L    + +Y   +
Sbjct:    4 FLSNSCPSTYALGTFAILWVLVWFYRDNLKITRVSEKHVFVTGCDSGFGNLLCKRLDKRGFRVLAGC--LTEKGADDLKRAAGPFLKTCILDVTSSASIQKAMEWTKKEVGDKG--LWGLVNNAGRSLPMGPSEWMK---IEDFESTLKVNMTGVIETTMTFLPLVKKARGRVVNVASVLGRVAANG-GGYCISKFAVESFSDCLRRDIQGFGVNVCIIEPGFFKTQVTSLEPIERELHRLWNQLTPEVKESYGDKYLDKYIWIQRLIMNAICDSDLSKVTNCMEHALLAVHPRTRYSAGW 296

[Close]

Query:  140 FLSLVLGAIIGLIVWIILSELQLFYEDLHKV-EVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAG----VGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI---------LLSTNKVFGTEETKLYGEKFIKKSEDILRNWVES-ASVNFQEVINALESAILNRTYQYKYKPNF 988
            FLS    +   L  + IL  L  FY D  K+  V  K V VTGCDSGFG +L + L KRG  V AG   L  +GA  LK      +K   +DVT    +++ +   ++ + D    LW +VNNAG    +G S+ M+   I+     L+VN  G++     FLPL+ +  GR+VN+ S+ G V +   GGYC SKF  E+ SD LR ++   G+ V  I P  +KT +         L         E  + YG+K++ K   I R  + +    +  +V N +E A+L    + +Y   +
Sbjct:    4 FLSNSCPSTYALGTFAILWVLVWFYRDNLKITRVSEKHVFVTGCDSGFGNLLCKRLDKRGFRVLAGC--LTEKGADDLKRAAGPFLKTCILDVTSSASIQKAMEWTKKEVGDKG--LWGLVNNAGRSLPMGPSEWMK---IEDFESTLKVNMTGVIETTMTFLPLVKKARGRVVNVASVLGRVAANG-GGYCISKFAVESFSDCLRRDIQGFGVNVCIIEPGFFKTQVTSLEPIERELHRLWNQLTPEVKESYGDKYLDKYIWIQRLIMNAICDSDLSKVTNCMEHALLAVHPRTRYSAGW 296

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Match: atp13a1 (ATPase type 13A1 [Source:Xenbase;Acc:XB-GENE-984166])

HSP 1 Score: 167.933 bits (424), Expect = 9.411e-48
Identity = 97/297 (32.66%), Postives = 164/297 (55.22%), Query Frame = 2

Query:  224 HKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRN----------------WVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            H  E  +K+VLVTGCDSGFG  LA+ L  +G  V+AG L  +   A V + +S+    ++ I+++V K +EV+  + I+R+ LT+ +  LW VVNNAG+     +EF  ++  +++ EVN  G +RV +  LPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     ++   ++  E+ K  G+K      ++++N                +  S S +  EVI+A+  A+   T   +Y P   +   RM+I+     +++++I
Sbjct:   44 HTAE-DSKAVLVTGCDSGFGFSLAKHLHNKGFIVYAGCLFKDKGEAGVKELDSMKSDRMRTIQLNVVKQDEVDRTVEIIRENLTNPEKGLWGVVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRVTKACLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNF-----IAGTSLYSPEKIKAIGDKMWADLPEVIKNDYGKKYFDEKIATMNTYCNSGSTDTSEVIDAITHALTASTPYTRYHPMDYYWWLRMQIMTHMPGAISDKI 334

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Match: atp13a1 (ATPase type 13A1 [Source:Xenbase;Acc:XB-GENE-984166])

HSP 1 Score: 167.548 bits (423), Expect = 1.333e-47
Identity = 97/297 (32.66%), Postives = 164/297 (55.22%), Query Frame = 2

Query:  224 HKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRN----------------WVESASVNFQEVINALESAILNRTYQYKYKP---NFVFRMKILMMKANSLNNRI 1042
            H  E  +K+VLVTGCDSGFG  LA+ L  +G  V+AG L  +   A V + +S+    ++ I+++V K +EV+  + I+R+ LT+ +  LW VVNNAG+     +EF  ++  +++ EVN  G +RV +  LPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     ++   ++  E+ K  G+K      ++++N                +  S S +  EVI+A+  A+   T   +Y P    +  RM+I+     +++++I
Sbjct:   53 HTAE-DSKAVLVTGCDSGFGFSLAKHLHNKGFIVYAGCLFKDKGEAGVKELDSMKSDRMRTIQLNVVKQDEVDRTVEIIRENLTNPEKGLWGVVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRVTKACLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNF-----IAGTSLYSPEKIKAIGDKMWADLPEVIKNDYGKKYFDEKIATMNTYCNSGSTDTSEVIDAITHALTASTPYTRYHPMDYYWWLRMQIMTHMPGAISDKI 343

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Match: mgc89248 (MGC89248 protein [Source:NCBI gene;Acc:448371])

HSP 1 Score: 129.413 bits (324), Expect = 1.174e-33
Identity = 84/193 (43.52%), Postives = 113/193 (58.55%), Query Frame = 2

Query:  242 NKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLS 808
            +K VL+TGCDSGFG +LA+ L +RG+ V A  L  N  GA  LK   +S ++ + +DVT  + V      V   + D    LW +VNNAG+       E+L  +  R +++VN LG++ V    LPL+R   GRIVN++SI+G V +   GGYC SKF  EA SD LR EL P G+ V  I P  +KT IL S
Sbjct:   30 DKYVLITGCDSGFGNLLAKQLHRRGVQVLAACLTQN--GAEELKKETSSRLRTVILDVTDSQSVSATAKWVSHIVQDQG--LWGLVNNAGILIPVTPNEWLKKEDFRTIIDVNLLGMVDVTLNLLPLIRKAKGRIVNVSSIAGRV-AICGGGYCISKFGVEAFSDTLRRELRPFGVTVSIIAPDFFKTLILES 217

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Match: mgc89248 (MGC89248 protein [Source:NCBI gene;Acc:448371])

HSP 1 Score: 128.257 bits (321), Expect = 1.560e-32
Identity = 91/273 (33.33%), Postives = 142/273 (52.01%), Query Frame = 2

Query:  212 YEDLHKVE-VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV--VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL------LSTNKVFG--TEETKL-YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNF 988
            Y+D H +  + +K VL+TGCDSGFG +LA++L +RG+ V A  L     GA  LK  +   ++ + +DVT    V+       Q + D    LW +VNNAG+       E+L  +   +++ VN LGL+ V    L L+R   GR+VN+ S++G +     GGYC SK+  E+ SD+LR E+ P G+ V  + P  +KT I        S  + +   TEE +  YG+++ KKS +  +  V     N   V + LE A+     + +Y   +
Sbjct:   18 YKDRHILHNLTDKYVLITGCDSGFGNLLARNLDRRGIRVLAACLT--DRGAEELKKQTSDRLQTVLLDVTDSNSVKTAANWASQIVGDKG--LWGLVNNAGISFPCAPNEWLTKEDFMKVMNVNLLGLIDVTINMLHLIRKARGRVVNIASVAGRITISG-GGYCMSKYGVESFSDSLRREMRPFGVKVCIVEPGFFKTQITNTDLVKQSLERAWNSTTEEIRQSYGQEYFKKSCNASQTIVPLCKANLSLVTDCLEHALTAAHPRTRYSAGW 285

HSP 2 Score: 69.707 bits (169), Expect = 2.069e-12
Identity = 41/89 (46.07%), Postives = 56/89 (62.92%), Query Frame = 2

Query:  479 LWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFE 739
            LW +VNNAG+       E+L  +  R +++VN LG++ V    LPL+R   GRIVN++SI+G V +   GGYC SKF  EA SD LR+ 
Sbjct:  308 LWGLVNNAGILIPVTPNEWLKKEDFRTIIDVNLLGMVDVTLNLLPLIRKAKGRIVNVSSIAGRV-AICGGGYCISKFGVEAFSDTLRYS 395

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Match: rdh5 (retinol dehydrogenase 5 [Source:NCBI gene;Acc:496830])

HSP 1 Score: 125.561 bits (314), Expect = 3.248e-32
Identity = 93/297 (31.31%), Postives = 158/297 (53.20%), Query Frame = 2

Query:  149 LVLGAIIGLIVWIILSELQLFYEDLHKV-EVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHS-QMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI--LLSTNKVFG------TEETKL-YGEKFIK---KSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNF 988
            ++L A++  I W++         D  K+    NK V +TGCD+GFG +LA+ L+++G  V AG   L   GA  L+    + +K   +DVT  E + + +  V+  + D    L+ +VNNAG+ +     E++ I   +++++VNA G + V   FL L+ +  GRI+N+ SI G  +S   GGYC SK+  EA SD+LR ++   G+ V  I P  +KT +  L S  +           ETK+ YG+K+ +   K + ++ N++  A ++  +V   +E A+  R  + +Y P +
Sbjct:    5 VLLFAMVWAIGWLL--------RDRQKISRFSNKHVFITGCDTGFGNLLAKRLSRKGFQVLAGC--LTQAGADDLQKACPTGLKCTLLDVTSQESINKAVEWVKSEVGDRG--LYGLVNNAGIANPIGPTEWMTIQDYKRVMDVNAFGTIAVSLSFLSLIKKAQGRIINMASILGR-ISANGGGYCVSKYAVEAFSDSLRRDMQHFGVRVCIIEPGFFKTAVTNLDSIERSLQLLWDQMPPETKMTYGDKYFQQYLKVQRLIMNFICDADIS--KVPKCIEHALQARYPRTRYSPGW 286

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Mouse
Match: Bdh1 (3-hydroxybutyrate dehydrogenase, type 1 [Source:MGI Symbol;Acc:MGI:1919161])

HSP 1 Score: 165.236 bits (417), Expect = 8.565e-47
Identity = 94/285 (32.98%), Postives = 154/285 (54.04%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-KTYILLSTNKVFGTEET----------KLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            K++L+TGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  +R  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLLR   GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     L S  ++    +           K YG K+  +    +  +  S S +   VINA+  A+   T   +Y P   +   RM+I+     +++++I
Sbjct:   56 KAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKI 340

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Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-KTYILLSTNKVFGTEET----------KLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            K++L+TGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  +R  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLLR   GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     L S  ++    +           K YG K+  +    +  +  S S +   VINA+  A+   T   +Y P   +   RM+I+     +++++I
Sbjct:   56 KAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKI 340

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Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-KTYILLSTNKVFGTEET----------KLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            K++L+TGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  +R  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLLR   GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     L S  ++    +           K YG K+  +    +  +  S S +   VINA+  A+   T   +Y P   +   RM+I+     +++++I
Sbjct:   56 KAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKI 340

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Mouse
Match: Sdr9c7 (4short chain dehydrogenase/reductase family 9C, member 7 [Source:MGI Symbol;Acc:MGI:1917311])

HSP 1 Score: 153.295 bits (386), Expect = 1.092e-42
Identity = 106/265 (40.00%), Postives = 150/265 (56.60%), Query Frame = 2

Query:  236 VKN---KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVL--KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL------LSTNKVFG--TEETK-LYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKP 982
            VKN   K V +TGCDSGFG +LA+ L  RGM V A  L    EGA  L    +  ++   +DVTK E V+E    VR  + +    LWA+VNNAGVG  S   E+L I    +++ +N +GL+ V    LP+++   GR+VN++S SG  V+ F GGYC SKF  EA SD++R ELH  G+ V  I P  YKT IL          K++    +ET+  YGE++ +     L N + SA     +V N++E AI++R+ + +Y P
Sbjct:   20 VKNLSEKYVFITGCDSGFGNLLAKQLVDRGMKVLAACLT--EEGAQKLLQDTSHQLQTFLLDVTKSENVKEAAQWVRDQVGEQG--LWALVNNAGVGLPSGPNEWLTIKDFVKVININLVGLIDVTLNMLPMIKKARGRVVNMSS-SGGRVAIFGGGYCVSKFGVEAFSDSIRRELHFFGVKVSIIEPGNYKTSILGQEALESRMKKLWDRLPQETRDSYGEEYFQTYTKKLVNLMRSAEPRISDVTNSMEHAIVSRSPRIRYNP 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Mouse
Match: Bdh1 (3-hydroxybutyrate dehydrogenase, type 1 [Source:MGI Symbol;Acc:MGI:1919161])

HSP 1 Score: 141.739 bits (356), Expect = 8.520e-39
Identity = 71/177 (40.11%), Postives = 109/177 (61.58%), Query Frame = 2

Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPL 751
               K++L+TGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  +R  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLL R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPL
Sbjct:   89 ASGKAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPL 265

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Match: sp|P29147|BDH_RAT (D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Rattus norvegicus OX=10116 GN=Bdh1 PE=1 SV=2)

HSP 1 Score: 166.007 bits (419), Expect = 2.459e-46
Identity = 96/285 (33.68%), Postives = 155/285 (54.39%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-KTYILLSTNKVFGTEET----------KLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  VR  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLLR   GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     L S  ++    +           K YG+K+  +    +  +  S S +   VINA+  A+   T   +Y P   +   RM+++     +++++I
Sbjct:   56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLLKDKGDAGVRELDSLKSDRLRTIQLNVCNSEEVEKAVETVRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDELPEVVRKDYGKKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQVMTHFPGAISDKI 340

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Match: sp|Q80XN0|BDH_MOUSE (D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Mus musculus OX=10090 GN=Bdh1 PE=1 SV=2)

HSP 1 Score: 165.236 bits (417), Expect = 5.991e-46
Identity = 94/285 (32.98%), Postives = 154/285 (54.04%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-KTYILLSTNKVFGTEET----------KLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            K++L+TGCDSGFG  LA+ L  +G  VFAG L  +   A V + +S+    ++ I+++V   EEVE+ +  +R  L D +  +W +VNNAG+     +EF  ++  +++ EVN  G +R  + FLPLLR   GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     L S  ++    +           K YG K+  +    +  +  S S +   VINA+  A+   T   +Y P   +   RM+I+     +++++I
Sbjct:   56 KAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVCNSEEVEKAVETIRSGLKDPEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRTTKSFLPLLRRAKGRVVNISSMLGRMANPARSPYCITKFGIEAFSDCLRYEMHPLGVKVSVVEPGNFIAATSLYSPERIQAIAKKMWDDLPEVVRKDYGRKYFDEKIAKMETYCNSGSTDTSSVINAVTHALTAATPYTRYHPMDYYWWLRMQIMTHFPGAISDKI 340

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Match: sp|Q02337|BDH_BOVIN (D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Bos taurus OX=9913 GN=BDH1 PE=1 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 2.743e-45
Identity = 95/293 (32.42%), Postives = 158/293 (53.92%), Query Frame = 2

Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL----------------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VL+TGCDSGFG  LA+ L   G  VFAG L  +     V + +S+    ++ ++++V K EEV++   ++R +L D +  LW +VNNAG+     +EF  ++  +++ EVN  G +RV + FLPL+ R  GR+VN++S+ G + +     YC +KF  EA SD LR+E+HPLG+ V  + P  +    + +T+   GTE  +                 YG K+  +    + ++  S S +   VI A+  A+   T   +Y P   +   RM+I+     ++++RI
Sbjct:   53 VGSKAVLITGCDSGFGFSLAKHLHSEGFLVFAGCLMKDKGSDGVKELDSMKSDRLRTVQLNVCKSEEVDKAAEVIRSSLEDPEKGLWGLVNNAGISTFGDVEFTSMETYKEVAEVNLWGTVRVTKAFLPLIRRAKGRVVNISSMMGRMANVARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNF----IAATSLYGGTERIQAIANKMWEELPEVVRQDYGRKYFDEKVARMESYCTSGSTDTSPVIKAVTHALTATTPYTRYHPMDYYWWLRMQIMTHFPGAISDRI 341

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Match: sp|Q8NEX9|DR9C7_HUMAN (Short-chain dehydrogenase/reductase family 9C member 7 OS=Homo sapiens OX=9606 GN=SDR9C7 PE=1 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 4.875e-42
Identity = 98/259 (37.84%), Postives = 145/259 (55.98%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK--MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTN---------KVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKP 982
            K V +TGCDSGFG +LA+ L  RGM V A       EG+  L+ ++  ++    +DVTK E ++     VR  + +    LWA+VNNAGVG  S   E+L  D   +++ VN +GL+ V    LP++ R  GR+VN++S SG  V+   GGYC SKF  EA SD++R EL+  G+ V  I P  Y+T IL   N         +    E    YGE + +   D L+N ++ A    ++VIN++E AI++R+ + +Y P
Sbjct:   26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFT--EEGSQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVGEQG--LWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSS-SGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNP 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Match: sp|Q8K3P0|DR9C7_MOUSE (Short-chain dehydrogenase/reductase family 9C member 7 OS=Mus musculus OX=10090 GN=Sdr9c7 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 7.637e-42
Identity = 106/265 (40.00%), Postives = 150/265 (56.60%), Query Frame = 2

Query:  236 VKN---KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVL--KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL------LSTNKVFG--TEETK-LYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKP 982
            VKN   K V +TGCDSGFG +LA+ L  RGM V A  L    EGA  L    +  ++   +DVTK E V+E    VR  + +    LWA+VNNAGVG  S   E+L I    +++ +N +GL+ V    LP+++   GR+VN++S SG  V+ F GGYC SKF  EA SD++R ELH  G+ V  I P  YKT IL          K++    +ET+  YGE++ +     L N + SA     +V N++E AI++R+ + +Y P
Sbjct:   20 VKNLSEKYVFITGCDSGFGNLLAKQLVDRGMKVLAACLT--EEGAQKLLQDTSHQLQTFLLDVTKSENVKEAAQWVRDQVGEQG--LWALVNNAGVGLPSGPNEWLTIKDFVKVININLVGLIDVTLNMLPMIKKARGRVVNMSS-SGGRVAIFGGGYCVSKFGVEAFSDSIRRELHFFGVKVSIIEPGNYKTSILGQEALESRMKKLWDRLPQETRDSYGEEYFQTYTKKLVNLMRSAEPRISDVTNSMEHAIVSRSPRIRYNP 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Match: A0A087UML5 (Estradiol 17-beta-dehydrogenase 2 (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_17677 PE=3 SV=1)

HSP 1 Score: 178.333 bits (451), Expect = 3.480e-48
Identity = 107/270 (39.63%), Postives = 156/270 (57.78%), Query Frame = 2

Query:  227 KVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLST----NKVFGTEETKL---YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKI 1006
            +++ +NK+VL+TGCDSGFG +LA+ L  RG  VFA  L  N  GA  LK   +  ++V+++DVT DE V+  +  V++ +   D  LWA+VNNAGV     +E   ID+ +  +EVNA+G +RV + FLPLLR   GR++NLTS++G V  P    Y  SKF A A ++ L+ E+   G+ VI++ P+ + T I+ +T    +  F + E  +   YGEKF+K  +  L      AS     VI+ LESAI        YKP   F  +I
Sbjct:   63 RIQPQNKAVLITGCDSGFGNLLAKRLDSRGFHVFASCLFPNGPGAEDLKKSCSKRLQVLELDVTNDESVQNAVNFVKENIGSSD--LWAIVNNAGVQKGFSIELTGIDEFKDTMEVNAIGPVRVTKAFLPLLRQAKGRVINLTSLAGRVTMPHFSPYTTSKFAAVAFTECLKQEMDVWGVKVISVEPEMFMTPIIHATIKNIDHTFDSLEKGIRADYGEKFLKGFKVFLECLTSMASTKINIVIDDLESAIALEYPNAIYKPRRNFAARI 330

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Match: K1P606 (D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Crassostrea gigas OX=29159 GN=CGI_10009966 PE=3 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.914e-46
Identity = 103/296 (34.80%), Postives = 171/296 (57.77%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV-VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI-----LLSTNKV----FGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVK 1084
            V  ++K+VL+TGCDSGFG  LA +L ++G  VFAG L  + EGA  LK NS  ++V+++DVT D +V + +  V++ L     +LWA+VNNAG+   Q +E+  + + +Q+++VN +G++RV + FLPLLR G GR++N+ S++G    P    Y  SK    A SD LR E+   G+ VITI P  Y+T I     L++ N+       +E  ++YGE++       +   +  A  N  EV+  +E A+ +   +++Y P ++  ++  ++ A  L++  +  F  S   +P K
Sbjct:   48 VAPEDKAVLITGCDSGFGHSLALNLDRQGFTVFAGCLFSDREGARSLKENSKNIQVVQLDVTDDWQVRKAVQTVKENLNGK--VLWALVNNAGIATFQEIEWCSVTQFQQIMDVNVIGVVRVTKAFLPLLRGGEGRVINVASLAGRFTVPAFAAYSMSKKACIAFSDGLRQEMAKFGVKVITIEPGLYRTPIVESDYLINANRRSWAETPSEVKEVYGEEYFDAFCKSISLHMRRARSNVGEVVKQMEEAVTSANPKHRYVPYWMSDLRATILGA--LSDETRDKFFLSTYKLPTK 339

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Match: A0A1L8GAD9 (Uncharacterized protein OS=Xenopus laevis OX=8355 GN=XELAEV_18027517mg PE=3 SV=1)

HSP 1 Score: 171.4 bits (433), Expect = 6.985e-46
Identity = 98/297 (33.00%), Postives = 167/297 (56.23%), Query Frame = 2

Query:  224 HKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRN----------------WVESASVNFQEVINALESAILNRTYQYKYKP---NFVFRMKILMMKANSLNNRI 1042
            H  E ++K+VLVTGCDSGFG  LA+ L  +G  VFAG L    +G  V + +S+    ++ ++++V K +EV+ G+ I+R+ L D +  LW VVNNAG+     +EF  ++  +++ EVN  G +RV +  LPL+ R  GR+VN++S+ G + +P    YC +KF  EA SD LR+E+HPLG+ V  + P  +     ++   ++  E+ K  G+K  ++  ++++N                +  S S +  EVI+A+  A+   T   +Y P    +  RM+I+     +++++I
Sbjct:   44 HSAE-ESKAVLVTGCDSGFGFSLAKHLHGKGFTVFAGCL-FKDKGEGVKELDSMKSDRMRTLQLNVVKPDEVDRGVEIIRENLKDPEKGLWGVVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVRVTKACLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNF-----IAATSLYSPEKIKAIGDKMWEELPEVIKNDYGRKYFDEKIARMNTYCNSGSTDTSEVIDAITHALTASTPYTRYHPMDYYWWLRMQIMTHMPGAISDKI 333

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Match: A0A210PFG1 (17-beta-hydroxysteroid dehydrogenase type 6 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT05973 PE=3 SV=1)

HSP 1 Score: 170.629 bits (431), Expect = 1.840e-45
Identity = 102/279 (36.56%), Postives = 160/279 (57.35%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNS--VVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRG-HGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI-----LLSTNKV----FGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFV--FRMKILMMKANSLNNR 1039
            K+V++TGCDSGFG  LA+ L K G  VFAG L  + +GA+ L+ +S   ++V++++VT D+ V   +  V+Q L D  + LWA VNNAG+   Q +E+  + + +Q+++VN +G++RV + FLPL+R   GR+VN+ S++G    P    Y  SK    A SD LR E++   I VIT+ P  YKT I     L+ TN+       TE   +YGE++       +   ++ A  N +EV++ +  A+  +    +Y PNF+   R  ILM    S+ +R
Sbjct:   64 KAVIITGCDSGFGNSLARRLDKLGFKVFAGCLAPDRKGATQLEEDSGGRIQVVELNVTDDQHVRCAVRFVKQNLGD--HTLWACVNNAGIAVFQEIEWCSVIQFQQIMDVNVIGVVRVTKAFLPLIRASKGRVVNVASLAGRFTVPSFAAYSMSKKACIAFSDGLRQEMNKFDIKVITVEPGLYKTPIAATDYLIDTNRKSWAETPTEVKDVYGEEYFDAFLKNIEGQMKRARSNVEEVVDQMVEAVTTKEPHVRYVPNFMSNVRASILMYLPTSITDR 340

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Match: F1SQX8 (3-hydroxybutyrate dehydrogenase 1 OS=Sus scrofa OX=9823 GN=BDH1 PE=1 SV=3)

HSP 1 Score: 168.703 bits (426), Expect = 7.028e-45
Identity = 99/288 (34.38%), Postives = 159/288 (55.21%), Query Frame = 2

Query:  236 VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            V +K+VLVTGCDSGFG  LA+ L  +G  VFAG L  +     V + +S+    ++ ++++V K EEVE+ +  +R +L D +  LW +VNNAG+     +EF  ++  +++ EVN  G +RV + FLPL+ R  GR+VN++SI G + +     YC +KF  EA SD LR+E+HPLG+ V  + P  +     L + +      TK+           YG K+  +    + N+  S S +   VINA+  A+ + T   +Y P   +   RM+I+     ++++RI
Sbjct:   56 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLKSDRLRTVQLNVCKSEEVEKVVETIRSSLQDPEKGLWGLVNNAGISTFGDVEFTSMETYKEVAEVNLWGTVRVTKSFLPLIRRAKGRVVNISSIMGRLANVSRSPYCITKFGVEAFSDCLRYEMHPLGVKVSVVEPGNFIVATSLYSPERIRAIATKMWEQVPEAVRQDYGRKYFDEMVARMENFCNSGSTDTSPVINAVTHALTSTTPYTRYHPMDYYWWVRMQIMTHLPGAISDRI 343

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Match: bdh1 (3-hydroxybutyrate dehydrogenase 1 [Source:NCBI gene;Acc:103031845])

HSP 1 Score: 156.377 bits (394), Expect = 1.693e-43
Identity = 100/342 (29.24%), Postives = 176/342 (51.46%), Query Frame = 2

Query:  140 FLSLVLG----AIIGLIVW-------------IILSELQLFYEDLHK-----VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV----VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY---KPNFVFRMKILMMKANSLNNRI 1042
            FL+L+LG    + + L+ W             ++L  L + Y  L +     V V+ K++L+TGCDSGFG  LA+   K G  VFAG L  +  G   ++  ++    +KV+++DV  D+EV + +  ++  L D +  LWAVVNNAG+     +EF  ++  +Q+ +VN  G +RV +  LPL+ R  GR+VN+ S+ G + +     YC SK+  EA SD LR+E+   G+ V  I P  +     + T  +  T   KL           YG+   ++   ++R++  S   +   V++ +  AI ++    +Y   +P++  RM+++     ++++R+
Sbjct:   18 FLTLILGFGLPSALNLLAWLCGLPEASATECVVLLYSLFVLYIALPRLPRGSVRVEGKALLITGCDSGFGHGLAKHFHKLGFTVFAGCLFKDKAGEGAVELENMHSDRMKVVQLDVCSDDEVSQAVEFIKANLDDPEKGLWAVVNNAGISTFGEVEFTTMETYKQVSDVNLWGTIRVTKAVLPLIRRAKGRVVNIASMYGRMGNALRSPYCISKYGVEAFSDCLRYEMKSWGVKVSVIEPGNFIVATGILTRDIVATTAEKLWKEAPPGVQEDYGKTHFEQYMALMRSYCNSGQRDISPVLDDITDAITSKRPYTRYNPMEPHWWIRMQVMTHLPAAISDRL 359

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Match: hsd17b2 (hydroxysteroid 17-beta dehydrogenase 2 [Source:NCBI gene;Acc:103032973])

HSP 1 Score: 148.673 bits (374), Expect = 2.451e-40
Identity = 109/313 (34.82%), Postives = 165/313 (52.72%), Query Frame = 2

Query:  104 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSEL-QLFY----EDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK--FNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV-GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNK----------VFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPN 985
            G W  ++   LG L+L   A  G +V  +LS    +FY     + H +   NKSVL+TGCDSGFG  LA+ L   G+ V+AGVL  +  GA  L+   +S + V+++DVT   ++   L +++    +    LW +VNNAGV G+    E LPI  LR+ L+VN +  + + Q FLPL+R   GRIVN++S++GEV  P    Y +SK    + S ALR EL   G+ V  I P  +KT IL +  +              E  + YG+++I   +  L +     S +   V+ A++ A+L+ T +  Y P 
Sbjct:   32 GSWVAWSVALLG-LTLCCMAPAGCLVLALLSVCYTVFYFTSRREEHLLPAHNKSVLITGCDSGFGHSLAKILDSAGIKVYAGVLKESGPGAQELRRLSSSQLTVLQLDVTDTSQISAALQLIKSQTGERG--LWGLVNNAGVIGYLCDGEILPIRILRKTLDVNFIAGVEMTQTFLPLIRQSKGRIVNISSLAGEVPFPGFAAYGSSKAAVISYSGALRQELSQWGVRVAVIQPGGFKTNILGNQQEWIQVQKEILSSLPQEVREAYGDEYICSLQQRLSSMNTQGSTDVGPVVEAIKHALLSETPRAFYHPG 341

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Match: hsd11b2 (hydroxysteroid 11-beta dehydrogenase 2 [Source:NCBI gene;Acc:103026519])

HSP 1 Score: 137.117 bits (344), Expect = 6.390e-36
Identity = 91/268 (33.96%), Postives = 147/268 (54.85%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKV--IKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV----GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL------------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            + V+ K+V +TGCD+GFG   A+ L   G  VFA VLNL  +GA  L+ +   ++  I++D+T+ ++V++ L      L      LWAVVNNAGV    G +++     +   R  +EVN  G L V + FLPLLR + GRI+N++S SG+   P L  Y ASK      ++ LR EL P G+ V TI P A+KT    S+N  +  ++ +             YGE+++ +++++ ++  ++A  +   V+N +  A+L    Q +Y
Sbjct:   81 LPVEGKAVFITGCDTGFGHATAKRLDALGFEVFATVLNLEGQGAKHLRSSCSPRLTLIQVDITQPQQVQQALITTTSKLGMKG--LWAVVNNAGVCVNFGDAELSL---MSNYRGCMEVNFFGTLSVTKAFLPLLRQNKGRILNISSPSGDQPFPCLASYGASKAALNLFTNTLRHELEPWGVKVCTILPSAFKTG--QSSNTEYWEKQYEHLLQNLPPSLLEEYGEEYLMETKELFQSHAKTACEDLSPVVNTIVEALLATHPQARY 341

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Match: ENSAMXT00000037146.1 (retinol dehydrogenase 7-like [Source:NCBI gene;Acc:103028830])

HSP 1 Score: 125.946 bits (315), Expect = 1.727e-32
Identity = 88/291 (30.24%), Postives = 149/291 (51.20%), Query Frame = 2

Query:  185 IILSELQLFYEDLHKVEVK-NKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGT---------EETK-LYGEKFIKKSEDIL-RNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMM 1015
            ++L  +  +Y +L +V  + NK V VTGCDSGFG +LA+ L K G  V A       E       ++ +    +DV K E +++    ++  + +    LWAVVNNAGV   S   +++ ++  + +L+VN  G++ V    +PL+ +  GR+VN+ S+ G  +SP  G YC SK+  E  +D+LR  L P G+ V+ I P  +KT +   TN +            +ETK  YG+ F+ K E ++   + +    +  + +  +E A+     + +Y P +  +M  L M
Sbjct:    9 VVLYYVVRWYRELARVPDRGNKYVYVTGCDSGFGNLLARHLDKCGFCVVAACFTEKGEEELKKSCSNRLTTTHLDVRKTESIDKVAAFIKNLVGNRG--LWAVVNNAGVSVPSGPCDWMTLEDYKSMLDVNLNGVIGVTLSVIPLIKKARGRVVNVASVFGR-ISPVGGPYCVSKYGVEGFNDSLRRGLKPFGVKVLCIEPGFFKTSV-TDTNLLIKCVRSLWDKLPQETKDDYGDDFVSKVEKVMEETFAKMPDSDLMKCVRCMEHAVSAVHPRTRYSPGWDAKMFWLPM 295

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Match: dhrs9 (retinol dehydrogenase 7-like [Source:NCBI gene;Acc:103044374])

HSP 1 Score: 123.635 bits (309), Expect = 1.075e-31
Identity = 85/283 (30.04%), Postives = 148/283 (52.30%), Query Frame = 2

Query:  185 IILSELQLFYEDLHKVEVKN-KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL-----------YGEKFIKKSEDILR-NWVESASVNFQEVINALESAILNRTYQYKYKPNF 988
            ++L  +  ++ +L +V  K+ K V +TGCDSGFG +LA+ L   G  V AG      E       ++ +  + +DVT ++ + +   I+R+ + +    LWAVVNNAGV   S   ++L ID    ++ VN  G++ V    LPL+ +  GR+VN+ S+ G  VSPF G YC SK+  EA +D+LR  +   G+ V+ I P  +KT +  +  K+      KL           YG  ++ + + +++  +V+    +  +V++ +E A+     + +Y P +
Sbjct:    9 VVLLYIYRWFRELKRVPNKSEKYVYITGCDSGFGNLLARHLDSLGFSVIAGCYTEKGEDELKKACSTRLSTVPLDVTNNDSIRKATEIIRKLVGERG--LWAVVNNAGVSVPSAPNDWLVIDDFMHMINVNLNGVIAVTLSVLPLIKKAKGRVVNVASVFGR-VSPFGGPYCVSKYGVEAFNDSLRMNMVHFGVKVLCIEPGFFKTSV--TDTKLLENSIQKLWERLPQDVKNDYGSDYMDRVKVMMKEKFVKMLDGDLMKVVSCMEHAVSAVHPRTRYSPGW 286

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000338.1 (pep scaffold:Pmarinus_7.0:GL483939:3417:7986:-1 gene:ENSPMAG00000000300.1 transcript:ENSPMAT00000000338.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 165.236 bits (417), Expect = 7.895e-48
Identity = 117/302 (38.74%), Postives = 158/302 (52.32%), Query Frame = 2

Query:  128 LPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVE-VKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK-FNSV-VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEET------------KLYGEKFIKKSEDILR-NWVESASVNFQEVINALESAILNRTYQYKYKP 982
            L L  L   LG ++GL V      LQ + ED  +V+ +  K+VLVTGCDSGFGL  A+ L   GM V AG L   S GAS L   NS  + V+ +DVT DE VEE L + +  +TD    LW VVNNAGVG    +E+  +   R + EVN  G +R+ + FLPLL R  GRIVN++SI+    S     Y  +K   E+ SDALR E+H  G+ V  I P  Y     L TN V  T               + YG +++      LR N   ++S +   V++AL  A+ +R  + +Y P
Sbjct:    3 LSLAGLVGALGTMLGLTVLY----LQSWQEDTKRVDALHKKAVLVTGCDSGFGLQFARELHGLGMTVLAGCLQTKSPGASELAALNSPRMHVLALDVTSDENVEEVLRVAQGIVTDNGLELWCVVNNAGVGCMGEIEWTRMSSFRMVAEVNLWGAVRITKAFLPLLRRSRGRIVNMSSIAARTSSYNNCAYAITKVALESFSDALRLEMHKWGVQVSLIEPGNYT----LHTNLVGDTSGADHFWNALPEPLQRDYGREYVAAFASQLRLNLESNSSTDASPVVSALRHAVTSRWPRRRYLP 296

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Match: bdh1 (3-hydroxybutyrate dehydrogenase, type 1 [Source:ZFIN;Acc:ZDB-GENE-070410-130])

HSP 1 Score: 142.51 bits (358), Expect = 2.902e-39
Identity = 88/300 (29.33%), Postives = 156/300 (52.00%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVL--NLNSEGASVLKF--NSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMD-----YILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL----------------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVF---RMKILMMKANSLNNRI 1042
            +++++K+VLVTGCDSGFGL LAQ L  +G  +FAG L  +   +GA  L+   +  +KV++M+V  D+EV + +  +R +L D +       LW VVNNAG+     +E+ P+D  + + EVN  G++R  +  LPL+ R  GR+VN++S+ G + +     YC +KF  EA SD LR+E+   G+ V  + P  +     ++   ++G +  K                 Y  ++  +   I+ ++    S +   VI  ++ A+ +     +Y P   +   R++ +      +++RI
Sbjct:   21 IQIRDKAVLVTGCDSGFGLSLAQHLHSKGFKIFAGCLLKDKGGDGAKQLEAMKSERLKVVQMNVASDDEVAKAVEFIRSSLPDPEDGERGTGLWGVVNNAGISTFGEIEWTPMDTYKNVAEVNLWGIVRTTKACLPLIRRARGRVVNISSMMGRMGNTARSPYCITKFGIEAFSDCLRYEMMRWGVKVSVVEPGNF-----IAATALYGEDRVKEIADGMWAKMSPQVQSDYTREYFDRQVTIMLSYTGGGSTDVSPVIEDIQDALTSYFPLTRYTPMDAYWWTRVQAITHLPAGISDRI 315

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004317.1 (pep scaffold:Pmarinus_7.0:GL477490:75458:82048:1 gene:ENSPMAG00000003943.1 transcript:ENSPMAT00000004317.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 136.346 bits (342), Expect = 9.677e-37
Identity = 76/200 (38.00%), Postives = 115/200 (57.50%), Query Frame = 2

Query:  227 KVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVL--KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNK 817
            +V ++ ++VL+TGCDSGFG  LA+ L   G+ V AG L  + EGA  L  K +  ++V+  DVT DE+V+E    V +     D  LWAVVNNAG+ H   +E   ++  ++   VN  G +R    FLPL++   GRIVN++SIS  + +PF   YC SK   +A S+ LR E+    + V+ I P  + ++  +  N+
Sbjct:   45 RVSLRGRAVLITGCDSGFGFELARRLDGMGVRVLAGCLQPDGEGARELASKSSDRLRVLPFDVTSDEQVQEARAAVTRMGRQAD--LWAVVNNAGITHLGEVEMCNMNSYQRAANVNLWGTIRTTMAFLPLVKASKGRIVNMSSISAHLHTPFNSAYCVSKSGVDAFSNCLRVEMKKWDVKVVLIEPGTFISHTNIMQNQ 242

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Match: dhrs9 (dehydrogenase/reductase (SDR family) member 9 [Source:ZFIN;Acc:ZDB-GENE-030131-1249])

HSP 1 Score: 130.954 bits (328), Expect = 6.334e-35
Identity = 91/250 (36.40%), Postives = 132/250 (52.80%), Query Frame = 2

Query:  242 NKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGG--YCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL------LSTNKVFGT---EETKLYGEKFIKKSEDI-LRNWVESASVNFQEVINALESAI 949
            +K V +TGCD+GFG +LA+ L  RG  V A       + A   + +  +K + +DVT +E V+     V+  + D    LW +VNNAGV      M++L I+  R  +EVNA+GL+ V    LP+L RG GR+VN+ S+ G +    LGG  Y  SKFC EA SD LR ++   GI VI I P  +KT +        S   ++ T   +    YGE FI+K  D   +N  +    +  +V  A+E A+
Sbjct:   40 DKYVFITGCDTGFGKLLAKRLDTRGFHVIAACFTEEGQNAIKAETSQRLKTVSLDVTNNESVKRAAEAVQGIVGDTG--LWGLVNNAGVCLPVGPMDWLTIEDFRPCMEVNAMGLVAVTLACLPMLKRGRGRVVNIASVMGRLA---LGGGSYSLSKFCVEAFSDILRRDVRVFGIKVIIIEPGFFKTNLTDEKKFNKSLRDIWATLPKDTRHQYGEDFIEKVTDANTKNLGKLLDTDISKVPIAVERAL 284

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004325.1 (pep scaffold:Pmarinus_7.0:GL477490:105787:111731:1 gene:ENSPMAG00000003950.1 transcript:ENSPMAT00000004325.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 129.798 bits (325), Expect = 1.189e-34
Identity = 73/190 (38.42%), Postives = 110/190 (57.89%), Query Frame = 2

Query:  227 KVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVL--KFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY 787
            +V ++ ++VL+TGCDSGFG  LA+ L   G+ V AG L  + EGA  L  K +  ++V+  DVT DE+V+E    V +     D  LWAVVNNAG+     +E   ++  +++ +VN  G +R    FLPL++ + GRIVN++SI+  + S F   YC +K   E  S  LR E+    + VI I P ++
Sbjct:   27 RVLLRGRAVLITGCDSGFGFELARRLDGMGVRVLAGCLQPDGEGARELASKSSDRLRVLPFDVTSDEQVQEARAAVTRMGRQAD--LWAVVNNAGIAQMGEVEMSNMNSYQRVADVNLWGTIRTTLAFLPLIKANKGRIVNISSIAARLPSAFTSSYCITKSGVEIFSTCLRLEMQKWDVKVIFIEPGSF 214

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
Match: YMR226C (NADP(+)-dependent serine dehydrogenase and carbonyl reductase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments [Source:SGD;Acc:S000004839])

HSP 1 Score: 70.0922 bits (170), Expect = 5.108e-14
Identity = 58/189 (30.69%), Postives = 90/189 (47.62%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLA-----QSLAKRGMFVFAGVLNLNSEGASVLKF---NSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL--RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINP 778
            K+VL+TG  +G G   A      S     + + A  L    E    +     N+ V V ++D+T+ E+++  +  + Q   D+D +    VNNAG    S  +  +  + ++ + + N   L+ + Q  LP+   +  G IVNL SI+G    P    YCASKF   A +D+LR EL    I VI I P
Sbjct:   14 KTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDIL----VNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAP 198

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
Match: AYR1 (Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase; NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase involved in phosphatidic acid biosynthesis; lipid droplet triacylglycerol lipase involved in the mobilization of non-polar lipids; found in lipid particles, the endoplasmic reticulum and the mitochondrial outer membrane; required for spore germination; role in cell wall biosynthesis; capable of metabolizing steroid hormones; oleic acid inducible [Source:SGD;Acc:S000001386])

HSP 1 Score: 68.1662 bits (165), Expect = 2.848e-13
Identity = 54/180 (30.00%), Postives = 82/180 (45.56%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKF-NSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPID----KLRQLLEVNALGLLRVCQKFLP-LLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVI 766
            K  +VTG   G G  + + LA+ G  V+A    L       ++F N  +K  K+D++K EE+      +R  L D    L  + NNAG    Q   F  +D     + Q  +VN  G + +C++    L++  G IV   S++G V  PF   Y ASK      +  L  E+ P  + VI
Sbjct:   10 KIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPMAQLAIQFGNDSIKPYKLDISKPEEIVTFSGFLRANLPDGKLDL--LYNNAG----QSCTFPALDATDAAVEQCFKVNVFGHINMCRELSEFLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVI 183

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
Match: YDL114W_mRNA (Putative short-chain dehydrogenase/reductase; YDL114W is not an essential gene [Source:SGD;Acc:S000002272])

HSP 1 Score: 53.9138 bits (128), Expect = 1.620e-8
Identity = 51/198 (25.76%), Postives = 94/198 (47.47%), Query Frame = 2

Query:  239 KNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL--RGHGRIVNLTSISGEVVSPFLGGYCASK-------FCAEAISDALRFELHPLGIPVITINPQAYKTYILL 805
            KN + L+TG  SG G  LA+ L++R   V    +      A V ++N++    + D+T  +E++     +++ +      +  ++NNAGV H + +E +   ++ QL+++N +G  R+   F   +     G I+N+ S+ GE+    L  Y ASK        C      +L  E +  GI  + + P   KT + +
Sbjct:   37 KNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQV-EYNNIF-YYQCDITSLDEIKN----LKKAIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTNMFI 228

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
Match: IFA38 (Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides [Source:SGD;Acc:S000000363])

HSP 1 Score: 49.6766 bits (117), Expect = 4.571e-7
Identity = 58/239 (24.27%), Postives = 94/239 (39.33%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLK-----FNSVVKVIKMDVTKDEEVE----EGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPID--KLRQLLEVNALGLLRVCQKFLPLL-----------RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITI--------------------NPQAYKTYILLSTNKVFGTEE 835
            K   +TG   G G   A+ +AKRG F    +    S+  ++ K      + VVK++ +D+ +D+E      + LC            +  +VNN G  HS  + FL  +  +LR ++ +N    L + Q   P +              G I+ + S  G + +P L  Y  SK   +  S++L  EL    I V  I                    NPQ +    L S  +  G++E
Sbjct:   63 KYCAITGASDGIGKEFARQMAKRG-FNLVLISRTQSKLEALQKELEDQHHVVVKILAIDIAEDKESNYESIKELC--------AQLPITVLVNNVGQSHSIPVPFLETEEKELRNIITINNTATLLITQIIAPKIVETVKAENKKSGTRGLILTMGSFGGLIPTPLLATYSGSKSFLQGWSNSLAGELSKDAIDVELIISYLVTSSMSKIRRSSLMIPNPQQFVKSTLRSVGRRCGSQE 292

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Match: EDO35671 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKS9])

HSP 1 Score: 161.77 bits (408), Expect = 2.437e-46
Identity = 94/256 (36.72%), Postives = 146/256 (57.03%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTL-TDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGH-GRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEE---------TKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYK 979
            K VL+TGCD+GFG  LA+ L K G+ VFAG L+   E       ++ +  I++DVTK  ++E+ LC++ Q + +    +LWA+VNNAG+G     +++ + +++++ +VN  GLL V + FLPLL+   GRIVN+ S +G++  P L  Y ASK+  ++ SDALR E+ P G+ V  I+P  +KT +  + N+    E             YGE F  K       W   AS N +EV+ A+E A+ +     +YK
Sbjct:   35 KWVLITGCDTGFGHQLAKRLDKLGLRVFAGCLSEGGEKNLQQCCSARLTTIRLDVTKQVDIEKTLCLITQEMASSSGSVLWAIVNNAGIGSGGPFDWITVQQMQRVFDVNVWGLLNVTKAFLPLLKKSCGRIVNVASCAGKLPGPGLSAYSASKYAVQSFSDALRIEMRPFGVSVHIIDPGFFKTNLTDAHNQKRQLEGLWNGLDQRVKDEYGEDFYLKGAIDFMGWF--ASSNTEEVVGAMEHAVTSCFPCVRYK 288

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Match: EDO41770 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3H1])

HSP 1 Score: 144.05 bits (362), Expect = 1.957e-39
Identity = 96/286 (33.57%), Postives = 149/286 (52.10%), Query Frame = 2

Query:  164 IIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTN---------KVFGTEETKLYGEKFIKKSEDILRNWVES-----ASVNFQEVINALESAILNRTYQYKY 976
            II L+V+ +    +L   D    ++++K VL+TGCDSGFG   A  L   G+ V A  L    E     +    V+  ++DVTK +EV+E    +++ L      LW VVNNAG+     ++++P+++ + + ++N  GL+ V + FLPL+ R  GRIVN+TSI+G    PF   Y  SK+ AEA SDA+R EL P GI V  + P  ++T +    N         +    ++   YGE +       ++N VE      AS N   V  A+  A+ +RT + +Y
Sbjct:   17 IIVLLVFTLWIFRKLVKSDCPIKDLESKYVLITGCDSGFGQETAILLDSLGVHVIATCLTARGEQELQKECCGRVRTFRLDVTKSKEVQEVYRALQEELPH-GTGLWGVVNNAGIAGVGPVDWIPVERFKHVADINLWGLVDVTKTFLPLVKRARGRIVNVTSIAGRFTLPFASPYSVSKYGAEAFSDAIRRELAPFGISVSIVEPGFFRTKMPTRENLTQQWETLWENLDDDKRDEYGEHYYNTR---VKNMVEGIADMMASPNTHHVCKAIAHALTSRTPKPRY 298

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Match: EDO35114 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SME6])

HSP 1 Score: 140.969 bits (354), Expect = 1.447e-38
Identity = 93/261 (35.63%), Postives = 137/261 (52.49%), Query Frame = 2

Query:  233 EVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK--MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGE--VVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL--LSTNKVFG------TEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            +  NK VLVTGCDSG G  LA  L   G  VF   L    +G   L+     + +   MDVT  E++ E    V+  L      LWAV NNAG      +E+ P+D  +++ +VN  GL+ V + FLPL++   GR+VN++SI G   + +     Y  +K+  EA SD LR E+ P G+ V  I PQA+KT +   ++T K          E  K YGEKF+++    LR ++  +S  F  V++A   AI +R  +++Y
Sbjct:   22 DYHNKYVLVTGCDSGLGRDLAIRLDGMGFHVFGACLT--QQGKRDLEQTCSKRTVGLLMDVTSHEQIAEAFEQVKSVLHS-GTGLWAVYNNAGYMTLAPLEWFPLDDYKRMADVNLWGLVDVTKTFLPLVKMARGRVVNVSSIVGGCLIANELTAPYSITKYGVEAFSDVLRREMLPWGVRVSIIEPQAFKTPLWDNIATKKYMSLWNGLDPEMKKEYGEKFVEEDVAFLRKFIHDSSTAFYMVVDAAVDAITSRDPKHRY 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Match: EDO48707 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIH3])

HSP 1 Score: 138.658 bits (348), Expect = 2.215e-38
Identity = 80/212 (37.74%), Postives = 121/212 (57.08%), Query Frame = 2

Query:  209 FYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVI--KMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEE 835
            ++  L   +   + VL+TGCDSGFG M A+ L   G  VFA  L    +G + LK +   +++   +DVT   ++EE   IV+  L      LWA++NNA V  +  +E++P++  R +L+VN  G++ V + FLPL++   GRIVN++S  G +  P +G YC SKF  EA S ALR EL P G+ VI + P  Y+T +    N +   E+
Sbjct:    9 YFHSLKVGDYCERYVLITGCDSGFGKMAAEQLDNMGFHVFASCLT--DKGQAFLKAHCSERLVTLPLDVTDSTQIEEAYNIVKCLLPLKG--LWALLNNAAVTTTGPIEWVPMETCRWVLDVNLYGMMDVTKTFLPLVKTSGGRIVNMSSAGGYISVPSIGVYCISKFAVEAFSSALRLELEPWGVKVIVVEPGGYRTEMTHKHNLIQALEQ 216

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Match: EDO35116 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SMF0])

HSP 1 Score: 140.584 bits (353), Expect = 2.425e-38
Identity = 93/261 (35.63%), Postives = 138/261 (52.87%), Query Frame = 2

Query:  233 EVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIK--MDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGE--VVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL--LSTNKVFG------TEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            +  NK VLVTGCDSG G  LA  L   G  VF   L    +G   L+     + +   MDVT  E++ E    V+  L      LWAV NNAG      +E+ P+D  +++ +VN  GL+ V + FLPL++   GR+VN++SI G   + +     Y  +K+  EA SD LR E+ P G+ V  I PQA+KT +   ++T K          E  K YGEKF+++    LR +++ +S  F  V++A   AI +R  +++Y
Sbjct:   22 DYHNKYVLVTGCDSGLGRDLAIRLDGMGFHVFGACLT--QQGKRDLEQTCSKRTVGLLMDVTSHEQIAEAFEQVKSVLPS-GTGLWAVYNNAGYMTLAPLEWFPLDDYKRMADVNLWGLVDVTKTFLPLVKMARGRVVNVSSIVGGCLIANELTAPYSITKYGVEAFSDVLRREMLPWGVRVSIIEPQAFKTPLWDNIATKKYMSLWNGLDPEMKKEYGEKFVEEDVAGLRKYIDMSSTAFYMVVDAAIDAITSRDPKHRY 279

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Match: bdh1 (D-beta-hydroxybutyrate dehydrogenase, mitochondrial [Source:NCBI gene;Acc:101169570])

HSP 1 Score: 163.31 bits (412), Expect = 4.578e-46
Identity = 102/288 (35.42%), Postives = 156/288 (54.17%), Query Frame = 2

Query:  230 VEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVL--NLNSEGASVLK-FNS-VVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLL-RGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSED-----------ILRNWVESASVNFQEVINALESAILNRTYQYKY---KPNFVFRMKILMMKANSLNN 1036
            VEVK K VL+TGCDSGFG  LA+ L + G  VFAG L  +   EGA  L+ F+S  +KV+++DV  D EV+  +  +R  L D    LWAVVNNAGV     +EF  +D  +Q+ EVN  G +RV +  LPL+ R  GR+VN+ S+ G + +     YC SK+  EA SD LR+E+   G+ V  + P  +     + T  V  T   KL+ E      ED           ++R++  S   +   V++ +  AI+++    +Y   +P++  RM+I+     ++++
Sbjct:   70 VEVKGKGVLITGCDSGFGHALAKHLHRLGFTVFAGCLLKDKGGEGAKALEEFHSDRMKVLQLDVCSDGEVKAAVEFIRNNLEDSQRGLWAVVNNAGVSTFGEVEFTSVDTYKQVSEVNLWGTIRVTKAVLPLIRRAKGRVVNIASMYGRMGNMMRSPYCVSKYGVEAFSDCLRYEMKSWGVKVSVVEPGNFIVATGILTRDVVATTANKLWSEAPPDVKEDYGKAHFEHLMALMRSYCNSGQKDDAPVMDDITDAIVSKRPYTRYSPMEPHWWIRMQIMTHLPGAISD 357

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Match: hsd11b2 (corticosteroid 11-beta-dehydrogenase isozyme 2 [Source:NCBI gene;Acc:100125474])

HSP 1 Score: 133.265 bits (334), Expect = 1.866e-34
Identity = 86/265 (32.45%), Postives = 142/265 (53.58%), Query Frame = 2

Query:  239 KNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKV--IKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGV----GHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKL------------YGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            + K+V +TGCDSGFG   A+ L   G  VFA VL L  +GA  L+ +   ++  +++D+T+ ++V++ L   +  L      LW +VNNAGV    G +++     +   R  +EVN  G L V + FLPLLR   GRI+ ++S +G+   P L  Y ASK     ++D LR EL P G+ V TI P +Y+T    ++N  +  ++ K             YGE ++ +++D+ +++   A+ +   VI+ +  A+L    Q +Y
Sbjct:   87 QGKTVFITGCDSGFGKEAAKRLDSLGFEVFATVLELTGDGARELQRSCSPRLTLLQVDITQPQQVQQALLDTKAKLGLRG--LWGLVNNAGVCVNFGDAELSL---MSNFRGCMEVNFFGTLSVTKSFLPLLRQAKGRIITISSPAGDQPFPCLAAYGASKAALNLLTDTLRHELEPWGVQVSTILPSSYRTG--RTSNHTYWDQQYKQLLQGLPPALLEEYGEDYVIETKDLFQSFASQANPDVTPVIDTIVQALLAAQPQARY 344

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Match: dhrs9 (retinol dehydrogenase 7 [Source:NCBI gene;Acc:101157170])

HSP 1 Score: 130.183 bits (326), Expect = 4.240e-34
Identity = 91/288 (31.60%), Postives = 145/288 (50.35%), Query Frame = 2

Query:  164 IIGLI-VWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVG-HSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYIL---LSTNKV------FGTEETKLYGEKFIKKS-EDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNF 988
            I+ L+ VW I    + F E        +K V +TGCDSGFG  LA+ L + G  V AG      E       +  +  + +DVTK E V +    ++  + +    LWAVVNNAGVG  S   ++L I+  + +L VN  G++ +    LPL++   GR+VN+ S+ G + SPF G YC SK+  EA +D LR  + P G+ V+ I P  +KT +    L  N +         +  + YG  F++K+ E +   + +    +  +V+  +E A+     +Y+Y P +
Sbjct:    5 ILALVAVWFIY---RWFKETKRVPNQGDKYVYITGCDSGFGNKLARHLDQLGFRVIAGCYTETGEVQLKKLCSERLNTVSLDVTKSESVAKAAAFIKTLVEEKG--LWAVVNNAGVGVPSGPNDWLTIEDFKSMLAVNLNGVIDITLSVLPLIKKARGRVVNVASVFGRI-SPFGGPYCVSKYGVEAFNDCLRLNMAPFGVKVLCIEPGFFKTSVTDTALVKNSLKKLWDKLPQDVQEEYGHAFLEKTLEGVDERFSQLTDGDLMKVVGCMEHAVAAVHPRYRYSPGW 286

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Match: zgc:113142 (D-beta-hydroxybutyrate dehydrogenase, mitochondrial [Source:NCBI gene;Acc:101170075])

HSP 1 Score: 126.331 bits (316), Expect = 1.656e-32
Identity = 80/254 (31.50%), Postives = 134/254 (52.76%), Query Frame = 2

Query:  245 KSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSV--VKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAY-------KTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKY 976
            ++VLVTGCDSGFG  LA +L + G  VFAG L+ + +GA  L  +    +KV+++DVTK+EEV++    V++ L +    LWAVVNNAG+     +E+  ++  R + +VN  G +R    FLPL+R   GR+V ++SI        +G Y  SK   EA +D LR E+   G+ V  I P  +       KT            +   ++  ++++ + D  ++  ++     + V+ A+  A+ +   + +Y
Sbjct:   43 RAVLVTGCDSGFGHRLAGALDRGGFVVFAGCLSPDGDGAQSLVRDGSGNLKVLQLDVTKEEEVQQARKTVQENLPEEG--LWAVVNNAGISDWAEIEWSSLEDFRHMADVNLFGSIRTTIAFLPLVRAAKGRVVFVSSIFAFFHCLNMGAYSVSKRGLEAFADCLRVEMASFGVKVSIIQPGNFAGATNILKTKTASDIWAKLDDDRKVVFNRRYVELANDYFKSTCKTGFKTAEPVVTAMLHALTSTRPKSRY 294

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Match: rdh5 (retinol dehydrogenase 5 [Source:NCBI gene;Acc:100125503])

HSP 1 Score: 122.479 bits (306), Expect = 2.661e-31
Identity = 80/213 (37.56%), Postives = 120/213 (56.34%), Query Frame = 2

Query:  182 WIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNS--VVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAG----VGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLR-GHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI 799
            W+    LQ+  E+ H+     K V VTGCDSGFG +L + L ++G  V AG L    +GA  LK  +   +K + +DVT  E +++ +   ++ + D    LW +VNNAG    +G S   E++ +D     L+VN +G++ +   FLPL++   GRIVN+ S+ G V +   GGYC SKF  EA SD LR +++  GI V  I P  +KT +
Sbjct:    8 WLFRDSLQI--ENFHE-----KYVFVTGCDSGFGHLLCKKLDRKGFRVLAGCLT--EKGADDLKRATGPYLKTVLLDVTSQESIQKTMEWTKKEVGDKG--LWGLVNNAGRSLPMGPS---EWMTVDDYHSTLKVNMIGVIAMTTTFLPLIKKARGRIVNVASVLGRVAANG-GGYCISKFAVEAFSDCLRRDINHFGISVCIIEPGFFKTAV 205

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BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Match: SMESG000039792.1 (SMESG000039792.1)

HSP 1 Score: 660.603 bits (1703), Expect = 0.000e+0
Identity = 324/330 (98.18%), Postives = 327/330 (99.09%), Query Frame = 2

Query:  104 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF 1093
            GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGAS LKF SVVKVIKMDVTKDEEVEEGLCIVRQTLT M+YILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPF+GGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRI+TGFRYSDISIPVKTEF
Sbjct:   19 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASDLKFISVVKVIKMDVTKDEEVEEGLCIVRQTLTGMNYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFIGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIRTGFRYSDISIPVKTEF 348

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Match: SMESG000039794.1 (SMESG000039794.1)

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 320/330 (96.97%), Postives = 327/330 (99.09%), Query Frame = 2

Query:  104 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF 1093
            GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLT M+YILWAVVNNAGVG  QMMEFLPIDKL+Q+L+VNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVV+PF+GGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRI+TGFRYSDISIPVKTEF
Sbjct:   19 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTGMNYILWAVVNNAGVGRFQMMEFLPIDKLQQMLDVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVNPFIGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIRTGFRYSDISIPVKTEF 348

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Match: SMESG000039796.1 (SMESG000039796.1)

HSP 1 Score: 625.935 bits (1613), Expect = 0.000e+0
Identity = 323/356 (90.73%), Postives = 338/356 (94.94%), Query Frame = 2

Query:   26 SVDLFFEKMNXXXXXXXXXXXXXXXXGFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF 1093
            SVDLFFEKMNLFLFILLIFLCQSFLFGFWFDF+YLPLGFLS+VLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSL+KRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTK+EEVEEGLCIVR+TLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSI+GEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITI PQAYKT IL STN+VFG  ET LYGEKFIKKSEDIL+NW+E AS NF EVIN LESAILNRTYQYKY PNF+FRMK+LM+  NS +N  +TGF+  DISIPVKTEF
Sbjct:  211 SVDLFFEKMNLFLFILLIFLCQSFLFGFWFDFSYLPLGFLSIVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLSKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKNEEVEEGLCIVRKTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSIAGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITIKPQAYKTSILFSTNEVFGANETNLYGEKFIKKSEDILQNWIEGASENFHEVINTLESAILNRTYQYKYIPNFIFRMKLLMLNFNSTSNLTRTGFQNGDISIPVKTEF 566

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Match: SMESG000039792.1 (SMESG000039792.1)

HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0
Identity = 306/317 (96.53%), Postives = 310/317 (97.79%), Query Frame = 2

Query:  143 LSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF 1093
            LS+ LG   GLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGAS LKF SVVKVIKMDVTKDEEVEEGLCIVRQTLT M+YILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPF+GGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRI+TGFRYSDISIPVKTEF
Sbjct:   73 LSVDLGD--GLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASDLKFISVVKVIKMDVTKDEEVEEGLCIVRQTLTGMNYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFIGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIRTGFRYSDISIPVKTEF 387

[Close]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Match: SMESG000039796.1 (SMESG000039796.1)

HSP 1 Score: 612.068 bits (1577), Expect = 0.000e+0
Identity = 297/330 (90.00%), Postives = 312/330 (94.55%), Query Frame = 2

Query:  104 GFWFDFNYLPLGFLSLVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYILLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAILNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF 1093
            GFWFDF+YLPLGFLS+VLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSL+KRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTK+EEVEEGLCIVR+TLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSI+GEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITI PQAYKT IL STN+VFG  ET LYGEKFIKKSEDIL+NW+E AS NF EVIN LESAILNRTYQYKY PNF+FRMK+LM+  NS +N  +TGF+  DISIPVKTEF
Sbjct:   19 GFWFDFSYLPLGFLSIVLGAIIGLIVWIILSELQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLSKRGMFVFAGVLNLNSEGASVLKFNSVVKVIKMDVTKNEEVEEGLCIVRKTLTDMDYILWAVVNNAGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTSIAGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITIKPQAYKTSILFSTNEVFGANETNLYGEKFIKKSEDILQNWIEGASENFHEVINTLESAILNRTYQYKYIPNFIFRMKLLMLNFNSTSNLTRTGFQNGDISIPVKTEF 348

The following BLAST results are available for this feature:

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Human
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Mouse
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SDR9C7	1.015e-42	37.84	short chain dehydrogenase/reductase family 9C memb...	[more]
BDH1	1.291e-40	32.64	3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Sym...	[more]
BDH1	1.291e-40	32.64	3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Sym...	[more]
BDH1	1.291e-40	32.64	3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Sym...	[more]
BDH1	1.291e-40	32.64	3-hydroxybutyrate dehydrogenase 1 [Source:HGNC Sym...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
dhs-20	4.430e-33	37.63	DeHydrogenases, Short chain [Source:UniProtKB/TrE...	[more]
dhs-16	5.989e-32	29.63	3 beta-hydroxysteroid dehydrogenase dhs-16 [Sourc...	[more]
drd-5	7.502e-28	31.48	Dietary restriction down regulated [Source:UniPro...	[more]
drd-5	7.502e-28	31.48	Dietary restriction down regulated [Source:UniPro...	[more]
dhs-2	2.418e-26	31.54	DeHydrogenases, Short chain [Source:UniProtKB/TrE...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CG8888	2.511e-23	28.42	gene:FBgn0033679 transcript:FBtr0088022	[more]
sro	1.525e-18	33.85	gene:FBgn0262112 transcript:FBtr0085481	[more]
CG3699	1.417e-15	34.41	gene:FBgn0040349 transcript:FBtr0070186	[more]
CG13377	1.201e-14	26.50	gene:FBgn0261446 transcript:FBtr0332990	[more]
CG13377	1.201e-14	26.50	gene:FBgn0261446 transcript:FBtr0070106	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bdh1	4.251e-46	32.64	3-hydroxybutyrate dehydrogenase, type 1 [Source:ZF...	[more]
hsd17b2	7.742e-35	36.29	hydroxysteroid (17-beta) dehydrogenase 2 [Source:Z...	[more]
hsd11b2	4.729e-34	31.23	hydroxysteroid (11-beta) dehydrogenase 2 [Source:Z...	[more]
rdh5	2.761e-32	32.89	retinol dehydrogenase 5 (11-cis/9-cis) [Source:ZFI...	[more]
rdh5	2.761e-32	32.89	retinol dehydrogenase 5 (11-cis/9-cis) [Source:ZFI...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atp13a1	9.411e-48	32.66	ATPase type 13A1 [Source:Xenbase;Acc:XB-GENE-98416...	[more]
atp13a1	1.333e-47	32.66	ATPase type 13A1 [Source:Xenbase;Acc:XB-GENE-98416...	[more]
mgc89248	1.174e-33	43.52	MGC89248 protein [Source:NCBI gene;Acc:448371]	[more]
mgc89248	1.560e-32	33.33	MGC89248 protein [Source:NCBI gene;Acc:448371]	[more]
rdh5	3.248e-32	31.31	retinol dehydrogenase 5 [Source:NCBI gene;Acc:4968...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Bdh1	8.565e-47	32.98	3-hydroxybutyrate dehydrogenase, type 1 [Source:MG...	[more]
Bdh1	8.565e-47	32.98	3-hydroxybutyrate dehydrogenase, type 1 [Source:MG...	[more]
Bdh1	8.565e-47	32.98	3-hydroxybutyrate dehydrogenase, type 1 [Source:MG...	[more]
Sdr9c7	1.092e-42	40.00	4short chain dehydrogenase/reductase family 9C, me...	[more]
Bdh1	8.520e-39	40.11	3-hydroxybutyrate dehydrogenase, type 1 [Source:MG...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P29147\|BDH_RAT	2.459e-46	33.68	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
sp\|Q80XN0\|BDH_MOUSE	5.991e-46	32.98	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
sp\|Q02337\|BDH_BOVIN	2.743e-45	32.42	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
sp\|Q8NEX9\|DR9C7_HUMAN	4.875e-42	37.84	Short-chain dehydrogenase/reductase family 9C memb...	[more]
sp\|Q8K3P0\|DR9C7_MOUSE	7.637e-42	40.00	Short-chain dehydrogenase/reductase family 9C memb...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A087UML5	3.480e-48	39.63	Estradiol 17-beta-dehydrogenase 2 (Fragment) OS=St...	[more]
K1P606	1.914e-46	34.80	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
A0A1L8GAD9	6.985e-46	33.00	Uncharacterized protein OS=Xenopus laevis OX=8355 ...	[more]
A0A210PFG1	1.840e-45	36.56	17-beta-hydroxysteroid dehydrogenase type 6 OS=Miz...	[more]
F1SQX8	7.028e-45	34.38	3-hydroxybutyrate dehydrogenase 1 OS=Sus scrofa OX...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bdh1	1.693e-43	29.24	3-hydroxybutyrate dehydrogenase 1 [Source:NCBI gen...	[more]
hsd17b2	2.451e-40	34.82	hydroxysteroid 17-beta dehydrogenase 2 [Source:NCB...	[more]
hsd11b2	6.390e-36	33.96	hydroxysteroid 11-beta dehydrogenase 2 [Source:NCB...	[more]
ENSAMXT00000037146.1	1.727e-32	30.24	retinol dehydrogenase 7-like [Source:NCBI gene;Acc...	[more]
dhrs9	1.075e-31	30.04	retinol dehydrogenase 7-like [Source:NCBI gene;Acc...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000000338.1	7.895e-48	38.74	pep scaffold:Pmarinus_7.0:GL483939:3417:7986:-1 ge...	[more]
bdh1	2.902e-39	29.33	3-hydroxybutyrate dehydrogenase, type 1 [Source:ZF...	[more]
ENSPMAT00000004317.1	9.677e-37	38.00	pep scaffold:Pmarinus_7.0:GL477490:75458:82048:1 g...	[more]
dhrs9	6.334e-35	36.40	dehydrogenase/reductase (SDR family) member 9 [Sou...	[more]
ENSPMAT00000004325.1	1.189e-34	38.42	pep scaffold:Pmarinus_7.0:GL477490:105787:111731:1...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 4


Match Name	E-value	Identity	Description
YMR226C	5.108e-14	30.69	NADP(+)-dependent serine dehydrogenase and carbony...	[more]
AYR1	2.848e-13	30.00	Bifunctional triacylglycerol lipase and 1-acyl DHA...	[more]
YDL114W_mRNA	1.620e-8	25.76	Putative short-chain dehydrogenase/reductase; YDL1...	[more]
IFA38	4.571e-7	24.27	Microsomal beta-keto-reductase; contains oleate re...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO35671	2.437e-46	36.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41770	1.957e-39	33.57	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35114	1.447e-38	35.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48707	2.215e-38	37.74	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO35116	2.425e-38	35.63	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
bdh1	4.578e-46	35.42	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
hsd11b2	1.866e-34	32.45	corticosteroid 11-beta-dehydrogenase isozyme 2 [So...	[more]
dhrs9	4.240e-34	31.60	retinol dehydrogenase 7 [Source:NCBI gene;Acc:1011...	[more]
zgc:113142	1.656e-32	31.50	D-beta-hydroxybutyrate dehydrogenase, mitochondria...	[more]
rdh5	2.661e-31	37.56	retinol dehydrogenase 5 [Source:NCBI gene;Acc:1001...	[more]

BLAST of 3-hydroxybutyrate dehydrogenase, type 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000039792.1	0.000e+0	98.18	SMESG000039792.1	[more]
SMESG000039794.1	0.000e+0	96.97	SMESG000039794.1	[more]
SMESG000039796.1	0.000e+0	90.73	SMESG000039796.1	[more]
SMESG000039792.1	0.000e+0	96.53	SMESG000039792.1	[more]
SMESG000039796.1	0.000e+0	90.00	SMESG000039796.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024934 ID=SMED30024934|Name=3-hydroxybutyrate dehydrogenase, type 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1272bp
CTAAATTTAAATAAAATTATTTTAGTCTGTTGATTTATTTTTCGAAAAAA
TGAATTTATTTTTGTTTATTTTATTAATTTTTCTCTGCCAATCGTTTTTG
TTTGGATTTTGGTTCGATTTCAATTATTTGCCATTGGGTTTCCTGAGTCT
TGTGTTGGGTGCAATAATAGGCTTGATCGTTTGGATAATATTATCGGAAC
TTCAACTTTTCTATGAAGATTTACACAAGGTCGAAGTAAAGAACAAAAGC
GTTTTGGTTACTGGATGTGATTCTGGATTCGGATTGATGCTCGCACAGTC
ATTGGCAAAGAGAGGAATGTTTGTCTTTGCTGGAGTTCTCAATTTAAATA
GTGAAGGAGCCAGCGTTTTGAAGTTCAATTCAGTTGTTAAAGTAATAAAA
ATGGACGTCACTAAGGATGAAGAAGTTGAAGAAGGACTTTGCATAGTTCG
ACAAACTCTTACTGACATGGATTATATTTTATGGGCAGTGGTAAACAATG
CTGGTGTGGGACATAGTCAAATGATGGAATTTTTACCCATTGATAAATTG
CGACAATTGTTGGAAGTTAATGCATTAGGGTTACTTCGAGTGTGTCAGAA
GTTTTTGCCTTTATTACGCGGTCATGGAAGGATTGTGAATTTAACTAGCA
TTTCAGGTGAGGTTGTAAGTCCATTTCTTGGTGGATATTGTGCTTCAAAG
TTTTGTGCTGAAGCCATTTCGGATGCTTTAAGATTCGAATTGCATCCTTT
GGGAATACCCGTTATTACTATTAACCCACAAGCTTACAAAACCTATATTT
TATTATCTACTAATAAAGTTTTCGGAACTGAAGAAACCAAGTTATATGGA
GAGAAGTTCATTAAAAAGTCTGAAGATATTCTTAGAAATTGGGTTGAGAG
CGCCAGTGTAAACTTCCAGGAAGTGATCAATGCATTGGAAAGTGCTATTT
TGAATCGGACTTACCAATATAAATACAAACCAAATTTCGTTTTCCGAATG
AAGATTTTGATGATGAAAGCCAATTCTCTTAATAATCGGATCCAAACGGG
ATTTCGCTATTCTGATATTTCAATCCCTGTAAAAACTGAATTTTGAATTT
ATTTTGAATTATTTTTATACTCGAAATTTACATTGTGATATTGTTTGATG
TTGTTTTGATCTTGCTTGGAAGTATTTAGTTAAAAAGGTTGTCGGAGAAC
TAATTTTACATGTTTTTCTTCGAGGCCCAAATATGTGTTATTTTTCTTTG
TTTAAAATATATGGTATTTATC

protein sequence of SMED30024934-orf-1

>SMED30024934-orf-1 ID=SMED30024934-orf-1|Name=SMED30024934-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=349bp
MNLFLFILLIFLCQSFLFGFWFDFNYLPLGFLSLVLGAIIGLIVWIILSE
LQLFYEDLHKVEVKNKSVLVTGCDSGFGLMLAQSLAKRGMFVFAGVLNLN
SEGASVLKFNSVVKVIKMDVTKDEEVEEGLCIVRQTLTDMDYILWAVVNN
AGVGHSQMMEFLPIDKLRQLLEVNALGLLRVCQKFLPLLRGHGRIVNLTS
ISGEVVSPFLGGYCASKFCAEAISDALRFELHPLGIPVITINPQAYKTYI
LLSTNKVFGTEETKLYGEKFIKKSEDILRNWVESASVNFQEVINALESAI
LNRTYQYKYKPNFVFRMKILMMKANSLNNRIQTGFRYSDISIPVKTEF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0016491	oxidoreductase activity

Vocabulary: **biological process**
Term	Definition
GO:0055114	oxidation-reduction process

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000035	Category 3 cell
PLANA:0000099	neuron
PLANA:0000418	head
PLANA:0002032	epidermal cell
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR036291	NAD(P)-bd_dom_sf
IPR002347	SDR_fam
IPR016040	NAD(P)-bd_dom

Vocabulary: **cellular component**
Term	Definition
GO:0016020	membrane
GO:0016021	integral component of membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002347	Short-chain dehydrogenase/reductase SDR	PRINTS	PR00081	GDHRDH	coord: 25..36 score: 40.48 coord: 96..115 score: 28.32 coord: 70..86 score: 33.62
IPR002347	Short-chain dehydrogenase/reductase SDR	PRINTS	PR00080	SDRFAMILY	coord: 25..36 score: 38.02 coord: 96..115 score: 30.22 coord: 76..84 score: 50.65
IPR002347	Short-chain dehydrogenase/reductase SDR	PFAM	PF00106	adh_short	coord: 1..133 e-value: 1.3E-23 score: 83.5
None	No IPR available	GENE3D	G3DSA:3.40.50.720		coord: 1..215 e-value: 1.3E-34 score: 121.6
None	No IPR available	PANTHER	PTHR43313:SF1	ALCOHOL DEHYDROGENASE-RELATED 31 KDA PROTEIN	coord: 1..194
None	No IPR available	PANTHER	PTHR43313	FAMILY NOT NAMED	coord: 1..194
IPR036291	NAD(P)-binding domain superfamily	SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	coord: 2..186