Ectonucleoside triphosphate diphosphohydrolase

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGE--VTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETF--GALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +FL++W  +A + NG   V+Q   C+   PGIS + ++   A + ++ CL +E + LIP+    K+  +LGATAGMR++           + +N    R IF  V + L  + +         ++++G  EG   WIT NY   TL     T  ++   E    GALD+GGASTQITFV    I   +T+   RLYG +Y+VY+HSYLC+G+ Q   RLL  L ++        +P   + +PC L G   +  L  +   PCV
Sbjct:   43 FGIVFDAGSSHTSLFLYQW--LANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCL-EEALVLIPEAQHRKTPTFLGATAGMRLL-----------SRKNSSQARDIFAAVTQVLGRSPVD----FWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQS--------RPAALLRHPCYLSGYQTTLALGPLYESPCV 293          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI--SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLK 1734
            N+T  GT +P AC  A++ LF  S C  Q +C F+ VYQP + G+F AF+ F   ++ L    + P    +   A   ++C R    V      ++R    W +  C   +Y+  LL   YGF+   W S+ F       ++GW+LGYM+N T MIP + P    + S G +VA  +VF+V+  +  + A +  + +WL+
Sbjct:  304 NLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQP---LSTVNATIWEFCQRPWKLVEASYPGQDR----WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAK-VVFMVLALVAVVGAAL-VQLFWLQ 494          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGE--VTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETF--GALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +FL++W  +A + NG   V+Q   C+   PGIS + ++   A + ++ CL +E + LIP+    K+  +LGATAGMR++           + +N    R IF  V + L  + +         ++++G  EG   WIT NY   TL     T  ++   E    GALD+GGASTQITFV    I   +T+   RLYG +Y+VY+HSYLC+G+ Q   RLL  L ++        +P   + +PC L G   +  L  +   PCV
Sbjct:   43 FGIVFDAGSSHTSLFLYQW--LANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCL-EEALVLIPEAQHRKTPTFLGATAGMRLL-----------SRKNSSQARDIFAAVTQVLGRSPVD----FWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQS--------RPAALLRHPCYLSGYQTTLALGPLYESPCV 293          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI--SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLK 1734
            N+T  GT +P AC  A++ LF  S C  Q +C F+ VYQP + G+F AF+ F   ++ L    + P    +   A   ++C R    V      ++R    W +  C   +Y+  LL   YGF+   W S+ F       ++GW+LGYM+N T MIP + P    + S G +VA  +VF+V+  +  + A +  + +WL+
Sbjct:  304 NLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQP---LSTVNATIWEFCQRPWKLVEASYPGQDR----WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAK-VVFMVLALVAVVGAAL-VQLFWLQ 494          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYL-KDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRL--YGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSV 1117
            YGI++DAGS+ T MF++KWP       G V Q   C     GIS + ++P+GA   +  CL ++ +  +PK     + +YLGATAGMR+     LNL       NP+A   +   V   L           R  +I+SG  EGV  W+T NYL ++ ++   V   F  +K T GA+DLGGASTQITF +    E   ++V+L  YG++Y VY+HS+LCYG+ Q   RLLA   +T               +PC  +G +   +L  +   PC       QNF +S 
Sbjct:   40 YGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGGGISSYADNPSGASQSLVGCL-EQALQDVPKERHAGTPLYLGATAGMRL-----LNLT------NPEASTSVLMAVTHTLTQYPFD----FRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRWFRPRKGTLGAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQVLQRLLASALQTHGF------------HPCWPRGFSTQVLLGDVYQSPCTMAQ-RPQNFNSSA 297          

Query: 1132 FEKFLNVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP 1623
            F     V+  G++DP  C+  V  LF  S C  + C FN V+QP + G F+AF+ F    + L      P        A + + C++    +      +     ++    C G ++V +LLS  YGF+   +  + F     +  +GW+LGYM+N T++IP + P
Sbjct:  293 FNSSARVSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADY----CAGAMFVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIPADPP 453          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIE---SGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            YGI++DAGS+ T +++++WP       G V+Q   C     GIS + N+P       E C+  ++   +P  L   + ++LGATAGMR++             +N  A   + E ++ +  S         R  +IISG  EGV  WIT NYL        +   ++     ET GALDLGGASTQI+FV+ E ++   S   +V LYG  Y +Y+HS+ CYG+++AE + LA L    + N      LT   NPC  +  + S+ +  +    C 
Sbjct:   57 YGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQ-KVKGQVPSHLHGSTPIHLGATAGMRLLR-----------LQNETAANEVLESIQSYFKSQPFD----FRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAML----LQNSPTKNHLT---NPCYPRDYSISFTMGHVFDSLCT 309          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRN--APPVVTPTTQKEREKENWRKWRCFGFIYVFEL-LSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLG--AFVAILIVF 1671
            +T+ GT DP  C++ V ++F    C  Q  C F+ VYQPKI G F+AFAGF    + L  +  S   D   F + + ++CS+N    P++ P     +  E + +  CF   Y++ L ++ Y F    W  I F   + N+++ WSLGYM++ T+ IP E PLI + +    FV  L  F
Sbjct:  323 ITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASAL-NLSGSFSLDT--FNSSTWNFCSQNWSQLPLLLP-----KFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFF 494          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIE---SGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            YGI++DAGS+ T +++++WP       G V+Q   C     GIS + N+P       E C+  ++   +P  L   + ++LGATAGMR++             +N  A   + E ++ +  S         R  +IISG  EGV  WIT NYL        +   ++     ET GALDLGGASTQI+FV+ E ++   S   +V LYG  Y +Y+HS+ CYG+++AE + LA L    + N      LT   NPC  +  + S+ +  +    C 
Sbjct:   57 YGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFKCSVKGSGISSYGNNPQDVPRAFEECMQ-KVKGQVPSHLHGSTPIHLGATAGMRLLR-----------LQNETAANEVLESIQSYFKSQPFD----FRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHPHGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEKKFLAML----LQNSPTKNHLT---NPCYPRDYSISFTMGHVFDSLCT 309          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRN--APPVVTPTTQKEREKENWRKWRCFGFIYVFEL-LSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLG--AFVAILIVF 1671
            +T+ GT DP  C++ V ++F    C  Q  C F+ VYQPKI G F+AFAGF    + L  +  S   D   F + + ++CS+N    P++ P     +  E + +  CF   Y++ L ++ Y F    W  I F   + N+++ WSLGYM++ T+ IP E PLI + +    FV  L  F
Sbjct:  323 ITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASAL-NLSGSFSLDT--FNSSTWNFCSQNWSQLPLLLP-----KFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIPAESPLIRLPIEPPVFVGTLAFF 494          

Query:  167 PAWYSMTIVFFTLSICGVVIICVLWAFANQLVYS------YGIIIDAGSTSTKMFLFKW---PEIATR-TNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAM-RLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFM-SKKETFGALDLGGASTQITF-VSNETIESGNT----KVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            PA+  + I FF+L +  V      W   + ++ +      + I+IDAGST T++ L+K+   P IA+     +V +    +  PG+S F   P+ A D +E  L       +P  +  K+ + L ATAG+R++               P  M   I E VE  + ++G         V ++ GS EGV +W T N L +TL  D+ T G   +   +  A DLGG STQ+T+  +NE + S +      +  +G +  +++HS+L  G   A   +L
Sbjct:    4 PAFSILLISFFSL-LSVVTTKTQYWCHGDGVLNNQHTCRFFTIVIDAGSTGTRLHLYKFIHDPAIASHGMPFKVEKEIFQEVKPGLSSFAKSPSSAADSLEPLLQ-RARKEVPHFMWEKTPITLKATAGLRLL---------------PGDMADDILESVEERIFNSGF-FAAFPDAVNVMPGSDEGVYSWFTLNILLETLFTDEPTVGHKPAAHRSVAAFDLGGGSTQLTYWPNNEAVFSEHVGYERDIDFFGHHIRLFTHSFLGNGLIAARLNIL 262          

Query:  248 ANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVK---------MCKSAPGISDFINDPNGAIDGIE--MCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKV-----TSGFMSKKETFGALDLGGASTQITF-------VSNETIESGNTKVRLYGE--NYNVYSHSYLCYGKSQA----EYRLLAFLSKTWIANYNPNQPLTPIDNPCM 1021
            A+    SYG+I DAGST T++F++ W  I+T ++ E+ Q++         M K +PG+S F   P  A + +   M L +     IP+  R  + V++ ATAGMR+I               P   +       R  L     M+     ++II G  EG+ +WI  NY               TS   ++++T G +D+GGAS QI F        S+  +E+ N   R       Y ++  ++L YG ++     E+ LL+ L          +Q  T I + CM
Sbjct:   37 ADDQERSYGVICDAGSTGTRLFVYNW--IST-SDSELIQIEPVIYDNKPVMKKISPGLSTFGTKPAQAAEYLRPLMELAERH---IPEEKRPYTPVFIFATAGMRLI---------------PDEQKEAVLKNLRNKLPKITSMQVLKEHIRIIEGKWEGIYSWIAVNYALGKFNKTATLDFPGTSPAHARQKTVGMIDMGGASAQIAFELPDTDSFSSINVENINLGCREDDSLFKYKLFVTTFLGYGVNEGIRKYEHMLLSKLK---------DQNGTVIQDDCM 293          

Query:  269 YGIIIDAGSTSTKMFLFKW-PEIATRTNGEV----TQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLR----DVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITF-VSN--ETIESGNTKVRLYGE-------NYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTP 1003
            YG+I DAGS+ T++F++   P     TN +     ++  + K  PG+S F + P   ++ +   L       IP     ++ + + ATAGMR++               P+A +    +++   L  GLK    LR    +++II G+ EG+ +WI  NY+      DK            G +D+GGAS QI F ++N  E+   GN      G         Y +YS ++L YG ++     L     + + + N N   +P
Sbjct:   49 YGVICDAGSSGTRLFVYTLKPLSGGLTNIDTLIHESEPVVKKVTPGLSSFGDKPEQVVEYLTPLLR-FAEEHIPYEQLGETDLLIFATAGMRLL---------------PEAQKDA--IIKN--LQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRF--DK------ENDSKVGMIDMGGASVQIAFEIANEKESYNGGNVYEINLGSIETNEDYKYKIYSTTFLGYGANEG----LKKYENSLVKSGNSNDSCSP 280          

Query:  269 YGIIIDAGSTSTKMFLFKW-PEIATRTNGEV----TQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLR----DVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITF-VSN--ETIESGNTKVRLYGE-------NYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTP 1003
            YG+I DAGS+ T++F++   P     TN +     ++  + K  PG+S F + P   ++ +   L       IP     ++ + + ATAGMR++               P+A +    +++   L  GLK    LR    +++II G+ EG+ +WI  NY+      DK            G +D+GGAS QI F ++N  E+   GN      G         Y +YS ++L YG ++     L     + + + N N   +P
Sbjct:   49 YGVICDAGSSGTRLFVYTLKPLSGGLTNIDTLIHESEPVVKKVTPGLSSFGDKPEQVVEYLTPLLR-FAEEHIPYEQLGETDLLIFATAGMRLL---------------PEAQKDA--IIKN--LQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRF--DK------ENDSKVGMIDMGGASVQIAFEIANEKESYNGGNVYEINLGSIETNEDYKYKIYSTTFLGYGANEG----LKKYENSLVKSGNSNDSCSP 280          

Query:  269 YGIIIDAGSTSTKMFLFKW-PEIATRTNGEV----TQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLR----DVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITF-VSN--ETIESGNTKVRLYGE-------NYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTP 1003
            YG+I DAGS+ T++F++   P     TN +     ++  + K  PG+S F + P   ++ +   L       IP     ++ + + ATAGMR++               P+A +    +++   L  GLK    LR    +++II G+ EG+ +WI  NY+      +  +          G +D+GGAS QI F ++N  E+   GN      G         Y +YS ++L YG ++     L     + + + N N   +P
Sbjct:   83 YGVICDAGSSGTRLFVYTLKPLSGGLTNIDTLIHESEPVVKKVTPGLSSFGDKPEQVVEYLTPLLR-FAEEHIPYEQLGETDLLIFATAGMRLL---------------PEAQKDA--IIKN--LQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRFDKENDSK--------VGMIDMGGASVQIAFEIANEKESYNGGNVYEINLGSIETNEDYKYKIYSTTFLGYGANEG----LKKYENSLVKSGNSNDSCSP 314          

Query:  179 SMTIVFFTLSICGVVIICVLWAFANQLVYS---YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNE-----TIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            S+ ++ F            L   A++  YS   Y  IIDAGST +++  +K+          + +    +  PG+S F ++P      I++ L DE    IPK   + + + L ATAG+R++                KA  ++  V + F  S   +    +  V+I+ G+ EG+ +W T N+L           G +SK     ALDLGG STQ+TF   +       +    +V    +  NV++HSYL  G   A + + 
Sbjct:   46 SVILLLFVFGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLL-DEARAFIPKEHWSSTPLVLKATAGLRLLP-------------ASKAENILNAVRDLFAKS---EFSVDMDAVEIMDGTDEGIFSWFTVNFLL----------GRLSKTNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVF 282          

Query:  179 SMTIVFFTLSICGVVIICVLWAFANQLVYS---YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNE-----TIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            S+ ++ F            L   A++  YS   Y  IIDAGST +++  +K+          + +    +  PG+S F ++P      I++ L DE    IPK   + + + L ATAG+R++                KA  ++  V + F  S   +    +  V+I+ G+ EG+ +W T N+L           G +SK     ALDLGG STQ+TF   +       +    +V    +  NV++HSYL  G   A + + 
Sbjct:   49 SVILLLFVFGFVSENASPYLARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLL-DEARAFIPKEHWSSTPLVLKATAGLRLLP-------------ASKAENILNAVRDLFAKS---EFSVDMDAVEIMDGTDEGIFSWFTVNFLL----------GRLSKTNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVF 285          

Query:  236 LWAFANQLVYS---YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNE-----TIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            L   A++  YS   Y  IIDAGST +++  +K+          + +    +  PG+S F ++P      I++ L DE    IPK   + + + L ATAG+R++                KA  ++  V + F  S   +    +  V+I+ G+ EG+ +W T N+L           G +SK     ALDLGG STQ+TF   +       +    +V    +  NV++HSYL  G   A + + 
Sbjct:  128 LARLASKFGYSKVQYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLL-DEARAFIPKEHWSSTPLVLKATAGLRLLP-------------ASKAENILNAVRDLFAKS---EFSVDMDAVEIMDGTDEGIFSWFTVNFL----------LGRLSKTNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFTHSYLGLGLMAARHAVF 345          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKS-APGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYL-----KDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            + YGI++DAGS+ T MF++KWP       G V+Q   C +   GIS +     GA   ++ C+ D+ M  IP      + VYLGATAGMR+     LN+        PK    + + VE  L S     K       I++G  EG   WIT NYL     K    G  +T G    ++T GALD GGASTQITFV+ +T+E+ +   K+RLYG +Y +Y+HS+LCYG+ Q   RLLA L     ++       T I +PC     ++S  L  +   PCV
Sbjct:   42 FMYGIVLDAGSSHTSMFIYKWPADKQNGTGIVSQHSECHAKGGGISSYAGVKGGAARSLKECM-DKAMREIPTVRYKHTPVYLGATAGMRL-----LNIS------KPKESAEVLKEVEEKLKSYPFSFK----GASILTGQEEGAYGWITVNYLLENYIKYGFVGQWITPG----RDTVGALDFGGASTQITFVTKQTVENKDDLMKLRLYGRDYQIYTHSFLCYGRDQVLLRLLAHLITIQGSD-------TSIIHPCYPADYSSSIKLSSVFDTPCV 294          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSL--GAFVAILIVFLVILSIGCLF 1701
            GT + + C   V  LF  S CS + C F+ V+QP ITG F+AF+ F   ++ L +         A     +R  C+ +    +    +K ++ E+  K  C   ++V  LL + Y FN+  +  I+F     + ++GWSLGYM++ ++++P E   +  SL  GA+  ++ +F ++L+   +F
Sbjct:  310 GTGNYNQCLGNVSQLFSFSSCSYSKCSFDGVFQPNITGNFMAFSAFFYTHSFLQEATGIKIWTPAHLEDAARVICNMS----LQEMGKKSQDNESRLKDYCAVSVFVRALLVNGYSFNDRTFPQISFQKKAGDTSVGWSLGYMLSLSNLLPAENVALKKSLRSGAWSFLIFLFSILLTSALIF 488          

Query:  203 LSICGVVIICV-LWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSK-----KETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +S  G++++ V    F       YGI++DAGS+ T MF++KWP       G V+Q   C+    GIS +      A   +E C+ D+    IPK  +  + VYLGATAGMR+     LN+        PK    + + V   L S     K       I++G  EG   WIT NYL +      +  GF+ +     ++T GALD GGASTQITFV+ +T+E+ +   K+RLYG +Y +Y+HS+LCYG+ QA  RLLA L KT  ++       T I +PC     ++S  L  +   PCV
Sbjct:   14 VSFVGILLLVVNTEDFKEPAQLMYGIVLDAGSSHTSMFIYKWPADKQNGTGIVSQHSECRVKGGGISSYAGIKGAAARSLEECM-DKATKSIPKSRQRITPVYLGATAGMRL-----LNIS------KPKESAEVLKEVGEKLKSYPFSFK----GASILTGQDEGAYGWITVNYLLENF----IKYGFVGQWITPGRDTVGALDFGGASTQITFVTKQTVENKDDLMKLRLYGRDYQIYTHSFLCYGQDQALLRLLAHLIKTQGSD-------TSIVHPCYPADYSSSIKLSSVFDTPCV 287          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVT--PTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPL 1626
            GT + + C   V  LF  S CS + C F+ V+QP ITG F+AF+ F  ++  L K         AD    ++  C+ +   +    PT     E ++ R +     +    L++ YGF++ ++  I+F   + + ++GWSLGYM++ ++++  E  +
Sbjct:  303 GTGNYNQCLGNVSQLFSFSSCSYSKCSFDGVFQPNITGNFMAFSAFYYIHQFLQKAAGITITSPADLEHAAQFVCNMSFQQMQNKFPT-----EGDHLRDYCADSVLMRVLLINGYGFSDLSFPHISFQEKVEDTSVGWSLGYMLSLSNLLDAENAM 454          

Query:  200 TLSICGVVIICVLWAFANQL----VYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYL-KDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIES--GNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            +L + G+V I +L    +++     Y YGI++DAGS+ T ++++KWP       G VTQ   C     GIS +      A   +E+CL   ++ + P R      VYLGATAGMR+++  N        Y+  + ++ + E ++ F  S         R   I+S   EGV  W+T NYL ++ ++   V     S ++T GALDLGGASTQITF + E +ES   +  +RL+G  Y++Y+HSYLCYGK +A   +LA+L  +   +Y      + + +PC       ++ L+++   PC +
Sbjct:   22 SLLLFGIVSILLLTVSIHEIREPAQYMYGIVLDAGSSHTALYVYKWPADKLNGTGVVTQHSECHVKGGGISGYAGQRGAAGRSLELCLKQAVLDIPPHRHHLTP-VYLGATAGMRLLKLSN-------PYKASQVLQEVKETIKSFPFS--------FRGAVILSSQDEGVYGWVTVNYLLENFIKYGYVGRWLNSGRKTVGALDLGGASTQITFETPERVESELNHMTLRLFGHEYSLYTHSYLCYGKEEALRMILAYLITS--QDYTST---SKMYHPCYPSDFINAFRLKEVFDSPCTA 302          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYV-FELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSL--GAFVAILIVFLVILS 1686
            ++T  GT D  +C      +F    CS + C FN V+QP I+G F+AF+ +   ++ L ++ +      A     ++  C+      +T  T K  + + + K  C   +Y+   +L  Y F+  ++ ++ F      A++GW+LGY+++ +S++P E   I   L   A+  ++ +  V+L+
Sbjct:  314 HITVQGTGDYQSCLGNTSKIFSFKSCSFSQCAFNGVFQPNISGGFMAFSAYYFTHSFLQQITEMKISTYAQLEEATQAVCNMT----ITEMTMKAPDLKKYLKDYCAVAVYIQVLMLRGYNFDENSFQNVAFQKKAGEASVGWALGYILSVSSLLPEESAAIRKGLCPAAWTGLMFLISVLLT 492          

Query:  224 IICVLWAFANQLV----YS--YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            II ++ A AN+      YS  +GI+ DAGS+ T +FL++W        G V+Q + C     GIS ++ +P GA + ++ CL D     IP   +  + VYLGATAGMR+     LNL+        ++  ++ EV +     T        R  +I++G  EG   WITTNYL ++         ++  K  +  GALDLGGASTQI+F   + +   N+   ++LYG  Y +Y++SYLCYGK QA  +L A+L K   ++       + I +PC  KG   +  L ++   PCV
Sbjct:   21 IIALILALANRQTLDQPYSTQFGIVFDAGSSHTALFLYQWQGNKENNTGIVSQKQSCDVDGDGISSYVQNPAGAGESLKKCL-DIAKAAIPTEQQKSTPVYLGATAGMRL-----LNLQ-----NQTQSDSILAEVAK-----TIQTYPFDFRGARILTGMEEGAYGWITTNYLLESFIKHTFEGSWIHPKAGKIIGALDLGGASTQISFTPKDPVRDPNSAFNLQLYGYKYELYTYSYLCYGKDQALKKLQAYLHKNAGSS-------SSISHPCYHKGYNLNLTLAELYNSPCV 293          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPCSQT-NCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFE-LLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK 1620
            + + GT +   C   ++N+   + C+ + +CGFN +YQP + G+F AF+ +   ++ L    K+P       ++     CS+N   +   T +    K  + K  C    Y+   LL  Y FNN  W  I+F   + + ++GW+LGYM+N T+MIP E+
Sbjct:  305 ILFKGTGNSSLCLSLIENIVNLTGCALSPDCGFNGIYQPPVNGEFFAFSAYFYTFDFLGLTPKAPL---TKVLSTIDTLCSKNWTAL---TAENPSIKPKYLKDYCASGHYITTILLKGYKFNN-TWDQISFVKQVADTDIGWTLGYMLNLTNMIPSER 456          

Query:  224 IICVLWAFANQLV----YS--YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            II ++ A AN+      YS  +GI+ DAGS+ T +FL++W        G V+Q + C     GIS ++ +P GA + ++ CL D     IP   +  + VYLGATAGMR+     LNL+        ++  ++ EV +     T        R  +I++G  EG   WITTNYL ++         ++  K  +  GALDLGGASTQI+F   + +   N+   ++LYG  Y +Y++SYLCYGK QA  +L A+L K   ++       + I +PC  KG   +  L ++   PCV
Sbjct:   21 IIALILALANRQTLDQPYSTQFGIVFDAGSSHTALFLYQWQGNKENNTGIVSQKQSCDVDGDGISSYVQNPAGAGESLKKCL-DIAKAAIPTEQQKSTPVYLGATAGMRL-----LNLQ-----NQTQSDSILAEVAK-----TIQTYPFDFRGARILTGMEEGAYGWITTNYLLESFIKHTFEGSWIHPKAGKIIGALDLGGASTQISFTPKDPVRDPNSAFNLQLYGYKYELYTYSYLCYGKDQALKKLQAYLHKNAGSS-------SSISHPCYHKGYNLNLTLAELYNSPCV 293          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPCSQT-NCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFE-LLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK 1620
            + + GT +   C   ++N+   + C+ + +CGFN +YQP + G+F AF+ +   ++ L    K+P       ++     CS+N   +   T +    K  + K  C    Y+   LL  Y FNN  W  I+F   + + ++GW+LGYM+N T+MIP E+
Sbjct:  305 ILFKGTGNSSLCLSLIENIVNLTGCALSPDCGFNGIYQPPVNGEFFAFSAYFYTFDFLGLTPKAPL---TKVLSTIDTLCSKNWTAL---TAENPSIKPKYLKDYCASGHYITTILLKGYKFNN-TWDQISFVKQVADTDIGWTLGYMLNLTNMIPSER 456          

Query:  257 LVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            L  +YG++ DAGS+ T ++L++WP       G + Q   C    PGIS + + P+GA   ++ C+ D+++ +IP   + ++ V LGATAGMR++              N    +LIF+ + + L    +      R  +I++GS EG   W+T NYL  T      +    +  +TFGA+DLGGASTQ+TF     I+  +T++  RLYG NY +Y+HSYLCYG+ Q   RLLA + + W +          + +PC  KG  A+  L  +   PCV
Sbjct:   10 LCNTYGMVFDAGSSHTTLYLYQWPANKENDTGIIRQAYSCDVQGPGISSYADTPSGAAASLQPCM-DQVLSVIPAAQQRQTPVLLGATAGMRLLR-----------IENATKTQLIFDEISKTLGGYPVD----FRGARILTGSEEGSLGWVTVNYLLGTFHTYLGSWVHPTGGQTFGAMDLGGASTQMTFQPTGAIQDKDTEMFFRLYGYNYTIYTHSYLCYGQDQVFKRLLANILQGWSSGL--------VAHPCYAKGYRANISLASVFNSPCV 262          

Query: 1144 LNVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVT--PTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSI 1689
            +NVT  GT DP  C +A+ N+F  S C S+ +C F+ VYQP   G+F AF+ F   ++ L    +    +    +    ++CS +   +    P   ++R  E      C   +Y+  LL   Y F++  W+ I F+    + ++GW+LGYM+N T+MIP E P    +    + +  +F ++LSI
Sbjct:  271 VNVTVEGTGDPTECHRAIGNVFNFSACQSKADCSFDGVYQPPAQGEFYAFSAFYYTFSFLNLTSRQSLSEANGTV---WNFCSSDWATLTGSFPLESRKRLLE-----YCSSGMYILTLLLDGYKFDSQTWNKIYFSKQAGSMDIGWTLGYMLNLTNMIPSEAPTYLKAHSYSLWVGAIFFIVLSI 448          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMS---------KKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            + YG++ DAGS+ T ++L++WP       G + Q   C    PGIS + + P+GA   ++ C+ D+++ +IP   + ++ V LGATAGMR++              N    +LIF+ + + L    +      R  +I++GS EG   W+T NYL  T  G    SG  +           +TFGA+DLGGASTQ+TF     I+  +T++  RLYG NY +Y+HSYLCYG+ Q   RLLA + + W +          + +PC  KG  A+  L  +   PCV
Sbjct:   10 HPYGMVFDAGSSHTTLYLYQWPANKENDTGIIRQAYSCDVQGPGISSYADTPSGAAASLQPCM-DQVLSVIPAAQQRQTPVLLGATAGMRLLR-----------IENATKTQLIFDEISKTLGGYPVD----FRGARILTGSEEGSLGWVTVNYLLGTFVGVS-RSGVHTYLGSWVHPTGGQTFGAMDLGGASTQMTFQPTGAIQDKDTEMFFRLYGYNYTIYTHSYLCYGQDQVFKRLLANILQGWSSGL--------VAHPCYAKGYRANISLASVFNSPCV 268          

Query: 1144 LNVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVT--PTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSI 1689
            +NVT  GT DP  C +A+ N+F  S C S+ +C F+ VYQP   G+F AF+ F   ++ L    +    +    +    ++CS +   +    P   ++R  E      C   +Y+  LL   Y F++  W+ I F+    + ++GW+LGYM+N T+MIP E P    +    + +  +F ++LSI
Sbjct:  277 VNVTVEGTGDPTECHRAIGNVFNFSACQSKADCSFDGVYQPPAQGEFYAFSAFYYTFSFLNLTSRQSLSEANGTV---WNFCSSDWATLTGSFPLESRKRLLE-----YCSSGMYILTLLLDGYKFDSQTWNKIYFSKQAGSMDIGWTLGYMLNLTNMIPSEAPTYLKAHSYSLWVGAIFFIVLSI 454          

Query:  155 DIPKPA-----WYSMTIVF----FTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGD----KVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            D PK A     W+   I+F    F L +  +V I V+          YGI++DAGS+ T +++++WP       G V Q+  CK    GIS + ++P  A   ++ C+N +   +IP++ + ++ VYLGATAGMR++   N  +              +   VE  L S         +  +II+G  EG   WIT NYL      D    K    F    ET GALDLGGASTQITF S   IES    +  RLYG++Y++Y+HS+LCYGK QA         +  IAN   +   + + +PC   G   +     + + PC+S
Sbjct:    2 DEPKAAKQKKTWHKKVIIFLGALFVLGVISLVAIAVVQNKPLPKNIKYGIVLDAGSSHTSVYIYEWPAEKENDTGVVQQINECKVEGNGISSYGHEPLKAGLSLQKCMN-KARQVIPEKQQRETPVYLGATAGMRLLRLTNATM-----------AEEVLSSVENTLRSFPFD----FQGARIITGQEEGAYGWITINYLLGNFIQDSGWFKYIPNF-KPTETSGALDLGGASTQITFESKREIESQENSLHFRLYGKSYDIYTHSFLCYGKDQA--------LRLQIANSIKDATDSILLDPCFNSGYRRNASTNDLYSSPCIS 301          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI-SMSLGAFVAILIVFLVIL 1683
            GT +   C++ V+ +F ++ C+ ++C FN V+QP + G F AF+ +  V N L    +    D      +   +CSR   P         + KE +    CF   Y+  LL   YGF++ NW+ I F   I +++ GW+LGYM+N T+MIP E P    +S   +  +++ F ++L
Sbjct:  316 GTGNYQLCKRNVQAIFNRTHCTYSHCSFNGVFQPSLDGTFGAFSAYYFVMNFLNLTNEQMSLDKVKETVER--HCSR---PWDEVKKDFPKIKEKYLSEYCFSGTYILNLLEYGYGFSSENWNDIRFLGKIKDSDAGWTLGYMLNLTNMIPAELPYSPPLSHAGYTGLMVFFSILL 486          

Query:  164 KPAWYSMTIVF----FTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGD----KVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            K  W+   I+F    F L +  +V I V+          YGI++DAGS+ T +++++WP       G V Q+  CK    GIS + ++P  A   ++ C+N +   +IP++ + ++ VYLGATAGMR++   N  +              +   VE  L S         +  +II+G  EG   WIT NYL      D    K    F    ET GALDLGGASTQITF S   IES    +  RLYG++Y++Y+HS+LCYGK QA         +  IAN   +   + + +PC   G   +     + + PC+S
Sbjct:    8 KKTWHKKVIIFLGALFVLGVISLVAIAVVQNKPLPKNIKYGIVLDAGSSHTSVYIYEWPAEKENDTGVVQQINECKVEGNGISSYGHEPLKAGLSLQKCMN-KARQVIPEKQQRETPVYLGATAGMRLLRLTNATM-----------AEEVLSSVENTLRSFPFD----FQGARIITGQEEGAYGWITINYLLGNFIQDSGWFKYIPNF-KPTETSGALDLGGASTQITFESKREIESQENSLHFRLYGKSYDIYTHSFLCYGKDQA--------LRLQIANSIKDATDSILLDPCFNSGYRRNASTNDLYSSPCIS 299          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI-SMSLGAFVAILIVFLVIL 1683
            GT +   C++ V+ +F ++ C+ ++C FN V+QP + G F AF+ +  V N L    +    D      +   +CSR   P         + KE +    CF   Y+  LL   YGF++ NW+ I F   I +++ GW+LGYM+N T+MIP E P    +S   +  +++ F ++L
Sbjct:  314 GTGNYQLCKRNVQAIFNRTHCTYSHCSFNGVFQPSLDGTFGAFSAYYFVMNFLNLTNEQMSLDKVKETVER--HCSR---PWDEVKKDFPKIKEKYLSEYCFSGTYILNLLEYGYGFSSENWNDIRFLGKIKDSDAGWTLGYMLNLTNMIPAELPYSPPLSHAGYTGLMVFFSILL 484          

Query:  164 KPAWYSMTIVF----FTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGD----KVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            K  W+   I+F    F L +  +V I V+          YGI++DAGS+ T +++++WP       G V Q+  CK    GIS + ++P  A   ++ C+N +   +IP++ + ++ VYLGATAGMR++   N  +              +   VE  L S         +  +II+G  EG   WIT NYL      D    K    F    ET GALDLGGASTQITF S   IES    +  RLYG++Y++Y+HS+LCYGK QA         +  IAN   +   + + +PC   G   +     + + PC+S
Sbjct:   38 KKTWHKKVIIFLGALFVLGVISLVAIAVVQNKPLPKNIKYGIVLDAGSSHTSVYIYEWPAEKENDTGVVQQINECKVEGNGISSYGHEPLKAGLSLQKCMN-KARQVIPEKQQRETPVYLGATAGMRLLRLTNATM-----------AEEVLSSVENTLRSFPFD----FQGARIITGQEEGAYGWITINYLLGNFIQDSGWFKYIPNF-KPTETSGALDLGGASTQITFESKREIESQENSLHFRLYGKSYDIYTHSFLCYGKDQA--------LRLQIANSIKDATDSILLDPCFNSGYRRNASTNDLYSSPCIS 329          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI-SMSLGAFVAILIVFLVIL 1683
            GT +   C++ V+ +F ++ C+ ++C FN V+QP + G F AF+ +  V N L    +    D      +   +CSR   P         + KE +    CF   Y+  LL   YGF++ NW+ I F   I +++ GW+LGYM+N T+MIP E P    +S   +  +++ F ++L
Sbjct:  344 GTGNYQLCKRNVQAIFNRTHCTYSHCSFNGVFQPSLDGTFGAFSAYYFVMNFLNLTNEQMSLDKVKETVER--HCSR---PWDEVKKDFPKIKEKYLSEYCFSGTYILNLLEYGYGFSSENWNDIRFLGKIKDSDAGWTLGYMLNLTNMIPAELPYSPPLSHAGYTGLMVFFSILL 514          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIE---SGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            YG+++DAGS+ T +++++WP       G V+Q   C     GIS + N+P  A    E C+  ++   +P+ L   + +YLGATAGMR++             +N  A R + E ++ +  S         R  +IISG  EGV  WIT NY+        +   ++     +T GALDLGGASTQI+FV+ E +E   S   +V LYG  Y +Y+HS+ CYG+++AE + LA L ++     N       I NPC  +G + ++ L  +    C 
Sbjct:   57 YGVVLDAGSSRTTVYVYQWPAEKENNTGVVSQTFRCSVKGSGISSYENNPQDAPKAFEDCIL-KVKEQVPEHLHGSTRIYLGATAGMRLLR-----------LQNETAAREVLESIQSYFKSQPFD----FRGAQIISGQEEGVYGWITANYIMGNFLEKNLWHMWVHPHGVDTTGALDLGGASTQISFVAGEKMEPNASDTVQVSLYGYTYTLYTHSFQCYGQNEAEKKFLAMLLQSPSTEAN-------ISNPCYPQGYSTAFTLGHVFGSLCT 309          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTN-CGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSR---NAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLG--AFVAILIVFLVI 1680
            +VT++GT DP  C++ V ++F  + C + + C F+ +YQPK+ G F+AFAGF   Y     +  S       F   S D+C       P +++      R  E + +  CF   Y++ LL + Y F    W  I F   + N+++ WSLGYM++ T+ IP   PLI + +    F+ +L  F  I
Sbjct:  322 SVTFMGTGDPRLCREKVASVFDFNACQEQDACSFDGIYQPKVQGPFVAFAGF---YYTASALNLSGSFSLTSFNDSSWDFCRHTWSELPALLS------RFDETYARSYCFSAHYIYHLLVNGYKFTEETWPQIRFEKEVGNSSIAWSLGYMLSLTNQIPAGSPLIHLPIQPPVFMGVLAFFTAI 497          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKET---FGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +F+++WP    +  G V+Q   C+   PGIS + +DP  A + ++ CL +E + LIP+    ++  +LG+TAGMR++           + +N    R I   V + L     K        KI++G  EG   WIT NY+   L   K +SG     E     GALDLGGASTQI+FV    I   +T+V  RLYG NY+VY+HSYLC+G+ Q   RLLA L++  +++      + P+ +PC   G  A   L  +   PC+
Sbjct:   43 FGIVFDAGSSHTSLFVYQWPANKEKDTGVVSQALTCQIEGPGISSYTSDPTQAGESLKSCL-EEALALIPQAQHPETPTFLGSTAGMRLL-----------SQKNSSQARDILAAVSQTLS----KSPVDFWGAKILAGQDEGAFGWITINYVLGMLL--KYSSGQWILPEEGMLVGALDLGGASTQISFVPQGPILDQSTQVTFRLYGANYSVYTHSYLCFGRDQILNRLLAKLAQDRLSS-----QVAPVRHPCYHSGYQAILPLSSLYDSPCI 295          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP 1623
            N+T  GT DP  C  A+++LF  S C  Q +C FN +YQP + G+F AF+ F   ++ L    +       D + K   +C +    V      +ER    W +  C   +Y+  LL   Y F+   W +I F     + ++GW+LG+M+N T MIP E P
Sbjct:  306 NLTVEGTGDPGNCVVALRSLFNFSSCKGQKDCAFNGIYQPPVHGQFYAFSNFYYTFHFLNLTSRQSLNTVNDTVWK---FCQKPWKLVEVSYPGQER----WLRDYCASGLYILVLLLEGYKFSEETWPNIQFQKQAGDTDIGWTLGFMLNLTGMIPAEAP 459          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKET---FGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +F+++WP    +  G V+Q   C+   PGIS + +DP  A + ++ CL +E + LIP+    ++  +LG+TAGMR++           + +N    R I   V + L     K        KI++G  EG   WIT NY+   L   K +SG     E     GALDLGGASTQI+FV    I   +T+V  RLYG NY+VY+HSYLC+G+ Q   RLLA L++  +++      + P+ +PC   G  A   L  +   PC+
Sbjct:   43 FGIVFDAGSSHTSLFVYQWPANKEKDTGVVSQALTCQIEGPGISSYTSDPTQAGESLKSCL-EEALALIPQAQHPETPTFLGSTAGMRLL-----------SQKNSSQARDILAAVSQTLS----KSPVDFWGAKILAGQDEGAFGWITINYVLGMLL--KYSSGQWILPEEGMLVGALDLGGASTQISFVPQGPILDQSTQVTFRLYGANYSVYTHSYLCFGRDQILNRLLAKLAQDRLSS-----QVAPVRHPCYHSGYQAILPLSSLYDSPCI 295          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP 1623
            N+T  GT DP  C  A+++LF  S C  Q +C FN +YQP + G+F AF+ F   ++ L    +       D + K   +C +    V      +ER    W +  C   +Y+  LL   Y F+   W +I F     + ++GW+LG+M+N T MIP E P
Sbjct:  306 NLTVEGTGDPGNCVVALRSLFNFSSCKGQKDCAFNGIYQPPVHGQFYAFSNFYYTFHFLNLTSRQSLNTVNDTVWK---FCQKPWKLVEVSYPGQER----WLRDYCASGLYILVLLLEGYKFSEETWPNIQFQKQAGDTDIGWTLGFMLNLTGMIPAEAP 459          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYL-KDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            YGI++DAGS+ T MF++KWP       G V Q   C     GIS + NDP+ A   +  CL ++ +  +PK     + +YLGATAGMR+     LNL       +P+A   + E V + L     +     R  +I+SG  EGV  W+T NYL ++ ++   V      +K T GA+DLGGASTQITF +    E  + +V  RLYG++Y VY+HS+LCYG+ Q   RLLA  S   I  +          +PC  KG +   +L+++   PC  G   Q
Sbjct:   40 YGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVRGGGISSYANDPSRAGQSLVECL-EQALRDVPKDRYASTPLYLGATAGMRL-----LNLT------SPEATAKVLEAVTQTLT----RYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPDNEVHLRLYGQHYRVYTHSFLCYGRDQVLQRLLA--SALQIHRF----------HPCWPKGYSTQVLLREVYQSPCTMGQRPQ 291          

Query: 1132 FEKFLNVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP 1623
            F     V+  GT++   C+  V  LF  S C  + C FN V+QP + G FIAF+ F    + L  V   P          +   C++    +      ++    ++    C   +++ +LLS  Y F+  ++  + F     +  +GW+LGYM+N T++IP + P
Sbjct:  293 FNSSATVSLSGTSNAALCRDLVSGLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLKTVMGLPVGTLKQLEDATETTCNQTWAELQARVPGQQTRLPDY----CAVAMFIHQLLSRGYRFDERSFRGVVFEKKAADTAVGWALGYMLNLTNLIPADLP 453          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKET---FGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +F+++WP    +  G V+Q   C+   PGIS + +DP  A + ++ CL +E + LIP+    ++  +LG+TAGMR++           + +N    R I   V + L     K        KI++G  EG   WIT NY+   L   K +SG     E     GALDLGGASTQI+FV    I   +T+V  RLYG NY+VY+HSYLC+G+ Q   RLLA L++        +  + P+ +PC   G  A   L  +   PC+
Sbjct:   43 FGIVFDAGSSHTSLFVYQWPANKEKDTGVVSQALTCQIEGPGISSYTSDPTQAGESLKSCL-EEALALIPQAQHPETPTFLGSTAGMRLL-----------SQKNSSQARDILAAVSQTLS----KSPVDFWGAKILAGQDEGAFGWITINYVLGMLL--KYSSGQWILPEEGMLVGALDLGGASTQISFVPQGPILDQSTQVTFRLYGANYSVYTHSYLCFGRDQILNRLLAKLAQ--------DSQVAPVRHPCYHSGYQAILPLSSLYDSPCI 292          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP 1623
            N+T  GT DP  C  A+++LF  S C  Q +C FN +YQP + G+F                                 Y   + P            +E W +  C   +Y+  LL   Y F+   W +I F     + ++GW+LG+M+N T MIP E P
Sbjct:  303 NLTVEGTGDPGNCVVALRSLFNFSSCKGQKDCAFNGIYQPPVHGQF---------------------------------YVEVSYP-----------GQERWLRDYCASGLYILVLLLEGYKFSEETWPNIQFQKQAGDTDIGWTLGFMLNLTGMIPAEAP 419          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSK------KETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            YG++ DAGST T +++++WP       G V+QV+ C  +  GIS + +DP GA   ++ CL D+ M +IP   + ++  YLGATAGMR++   N          + KA ++  EV +        +     R  +I++G+ EG   WIT NYL +TL    +   F  K       E  GALDLGGASTQITF    TIE  NT V  RLYG NY++Y+HSYLCYG+ QA  RL+A L +    +Y  N     I +PC  KG      + +I   PCV
Sbjct:   41 YGLVFDAGSTHTALYVYQWPADKENGTGIVSQVESCTVNGSGISSYADDPAGAGASLKPCL-DKAMAVIPVEQQWQTPTYLGATAGMRLLREQN----------STKAEQVFAEVSKAIR-----EFPVDFRGAQILTGNEEGSFGWITVNYLLETL----IKFSFAGKWEHPQNTEVLGALDLGGASTQITFQPGVTIEDKNTSVLFRLYGTNYSLYTHSYLCYGQIQASKRLMAALHQD--GSYVQN-----ISHPCYPKGYRRIITIAEIYDSPCV 292          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK-PLISMSLGAFVAILIVFLVILSIGCLFAII 1710
            +T  GT +P AC  A+  LF  +  +   CGF+ VYQP + G+F AFAGF   ++ L    +   +  +   A   D+C++N   +V    Q    KE+   +   G   +  L+  Y F+   W +I F+    NA++GW+LG+M+N T+MIP E    +     +  A  I F+V+  +  L AI+
Sbjct:  304 LTVTGTGNPAACPTAILKLFNLTCGANRTCGFDGVYQPPVRGQFFAFAGFYYTFSFLNLTGQ---QSLSHVNATVWDFCNKNWSELVETFPQN---KEHLHTYCVVGLYILTLLVDGYKFDEHTWSNIHFSQKAGNADIGWTLGFMLNLTNMIPTEALEHVKGHEPSLWAGAISFIVLAIVAGLVAIL 485          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYL-KDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            + YGI++DAGS+ T +F++KWP       G V++  MC    PGIS + + P  A   +E CL+  M   +PK     + +YLGATAGMR++              +P +   +  V     ++T           KI+SG  EGV  WIT NYL ++ ++   +     SKK+T GA+D GGASTQITF +++ IE    +V  +LYG+ Y VY+HS+LCYG+ Q   RLL+ + +    NY        + NPC   G   S  L  I   PC 
Sbjct:   36 FKYGIVLDAGSSHTAVFIYKWPADKENDTGVVSEHSMCDVEGPGISSYSSKPPAAGKSLEHCLSQAMRD-VPKEKHADTPLYLGATAGMRLL-----------TIADPPSQTCLSAV-----MATLKSYPFDFGGAKILSGEEEGVFGWITANYLLENFIKRGWLGEWIQSKKKTLGAMDFGGASTQITFETSDAIEDPKNEVMLKLYGQPYKVYTHSFLCYGRDQVLKRLLSKVLQA--ENYQET-----VANPCWPTGYRKSLSLSSIYDSPCT 287          

Query: 1144 LNVTYV--GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMS-LGAFVAILIVFLVILSIGCLFAII 1710
            LN T V  GT + + C   V  LF  + CS ++C F+ V+QP+++G FIAF+ F    + +  V + P    +D    +   C+ +   +     + E+   ++    C    +V+ L++  Y FNN ++ SI F       ++GW+LGYM+N T+MIP ++P    S L  +  ILI+  VI ++  L   +
Sbjct:  296 LNTTVVVSGTGNGNLCAVHVNKLFDFTSCSFSHCSFDGVFQPEVSGNFIAFSAFFYTVDFIRTVMERPVHSPSDLKDAAETICATSWNELYQKAPRLEKRLPDY----CATSTFVYLLITKGYNFNNRSFPSIAFQKKAGETSIGWALGYMLNLTNMIPAQEPASHRSMLYNYWVILILLFVITTLTALLTAV 484          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAID-GIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK-------ETFGALDLGGASTQITFV-SNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLPD 1129
            +GI++DAGS+ T ++++KWP       G V+QV+ CK   PGIS+F     G ID  +E C+ +    ++PK    ++ VYLGATAGMR++   N NL         K +  + E + R+            +  +II+G  EG   WIT NYL D        SG+ + K       ET+GALDLGGASTQITFV  N+ +ES    +  RLYG+NY+VY+HS+LCYGK QA   LL  L+K  + N N       I  PC   G      +  +   PC       + F TS+  P+
Sbjct:   49 FGIVLDAGSSHTSLYIYKWPAEKENDTGVVSQVEECKLKGPGISEFAKKL-GEIDIYLEACM-ERARTVVPKSQHAETPVYLGATAGMRLLRMKNENLA-------SKILSTVAESITRYPFD--------FQGARIITGQEEGAYGWITINYLLDKFIQK---SGWFNLKPRKGDTQETYGALDLGGASTQITFVPQNQVLESPENTLHFRLYGKNYSVYTHSFLCYGKDQA---LLQKLTKD-LKNTNGT-----IHEPCFHSGYQRRMNVSHLYEAPCT------RRFLTSLPFPE 312          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKS----RDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLIS-MSLGAFVAILIVF---LVILSIGCLFAIISYKWYW 1728
            GT D   CQ++++ LF  S C  + C F+ V+ P   G F AF+ F  V       F +   +   F +K       +CSR   P           KE +    CF   Y+  LL S Y F    W +I F   + + ++GW+LGYM+N T+MIP E+P  + +S   +V ++++F   LVI+ I  LF      ++W
Sbjct:  317 GTGDFQKCQQSIRPLFNTSYCPYSRCSFDGVFLPLPQGDFAAFSAFYYVMG-----FLNLTSEEGSFQSKVTSTLEAFCSR---PWAELQMYFGDVKEKYLSEYCFSGTYILTLLLSGYHFTAETWKNIHFMGKVQSTSVGWTLGYMLNLTNMIPSEEPSSTRLSHSTYVFLMVLFSLILVIVVIIGLFVCHRPSYFW 506          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGE--VTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETF--GALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +FL++W  +A + NG   V+Q   C+   PGIS + ++   A + ++ CL +E + LIP+    K+  +LGATAGMR++           + +N    R IF  V + L  + +         ++++G  EG   WIT NY   TL     T  ++   E    GALD+GGASTQITFV    I   +T+   RLYG +Y+VY+HSYLC+G+ Q   RLL  L ++        +P   + +PC L G   +  L  +   PCV
Sbjct:   43 FGIVFDAGSSHTSLFLYQW--LANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCL-EEALVLIPEAQHRKTPTFLGATAGMRLL-----------SRKNSSQARDIFAAVTQVLGRSPVD----FWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQS--------RPAALLRHPCYLSGYQTTLALGPLYESPCV 293          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI--SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLK 1734
            N+T  GT +P AC  A++ LF  S C  Q +C F+ VYQP + G+F AF+ F   ++ L    + P    +   A   ++C R    V      ++R    W +  C   +Y+  LL   YGF+   W S+ F       ++GW+LGYM+N T MIP + P    + S G +VA  +VF+V+  +  + A +  + +WL+
Sbjct:  304 NLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQP---LSTVNATIWEFCQRPWKLVEASYPGQDR----WLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAK-VVFMVLALVAVVGAAL-VQLFWLQ 494          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKS-APGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKET--FGALDLGGASTQITFVSNETI--ESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            +GI+ DAGS+ T +F+++WP       G V+Q   C++  PGIS + ++P    + ++ CL +E + LIPK    ++ ++LGATAGMR++           + +N      +F  V R L  + +      R  ++++G  EG   WIT NY+   L     +  ++   E    GALD+GGASTQITFV    I  ++     RLYG ++ VY+HSYLC+G+ QA  R+LA L +              I +PC   G   +  L  +   PC 
Sbjct:   43 FGIVFDAGSSHTSLFVYQWPANKENDTGIVSQALACQAEGPGISSYASNPARVGESLQGCL-EEALALIPKAKHHETPMFLGATAGMRLL-----------SRKNRSQAEDVFAAVSRALGQSPVD----FRGAELLTGQDEGAFGWITINYILGLLVKYSFSGEWIRPLEETLVGALDMGGASTQITFVPGGPILDKTAQATFRLYGADHTVYTHSYLCFGRDQALSRVLAELVQASTGLL--------IRHPCYHSGYRGTLALASLYESPCA 293          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSR-------NAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI--SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLK 1734
            N+T  GT +P AC +A++ LF  S C  + +C F  VYQP + G+F AF+ F   +N  + +   P    A+  A   ++C R       +APP           ++ W +  C   +Y+  LL   YGF+   W  I F      A++GW+LGYM+N T++IP E P    + S G + A ++   V+L++      ++ + +WL+
Sbjct:  303 NLTVEGTGNPGACVEALRKLFNFSSCDGREDCAFAGVYQPPVQGQFYAFSNFYYTFN-FLNLTSKPSLSGAN--ATIWEFCLRPWKLVEASAPP----------GQDRWLRDYCASGLYILTLLVEGYGFSEETWGGIEFRQQAGGADIGWTLGYMLNLTNLIPAEAPAQGWAQSFGVWAAGVV--FVVLTLAATLGAVAVQVFWLQ 494          

Query:  236 LWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVR-LYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSV----DLPDSL 1135
            L+A A  +   Y ++IDAGSTS+K+ +FKW +   + NG V +VKM K  PGIS + +    A   +E  +   +   IP   R  + V+L ATAGMR++              NP     I E ++  L   GL +     DV+I+SG  EG+ +WIT NYL   L    V    + +K+T GALDLGGASTQITFV      + +T  R L+G+ +N+YS+SYLCYGKS AE R+ A +          NQ    IDNPC  +G+       KI    CVS  Y+    G+++    DLP+++
Sbjct:   35 LYAIACNVGCVYTLLIDAGSTSSKLTVFKWKDWPFQKNGYVEEVKMAKVQPGISAYKDKSADAFAALEPHIMKLLGQTIPSESRHSTRVFLAATAGMRLL-----------TLENPLQSEAIIESLQLQLPQVGLMVDNPYSDVRIMSGRDEGIYSWITVNYLTKKLGSRNVPP--VDEKQTIGALDLGGASTQITFVPENNKPAPHTSTRNLFGKAFNLYSYSYLCYGKSAAEKRIWAEIIG--------NQSAREIDNPCFHQGNVVVVKTSKIFAEQCVSSKYADVLVGSALFPHKDLPENV 318          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPN-WHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAF---VAIL-IVFLVILSIG 1692
            NVT+ GT DP  C++ V+ +F    CSQ  C F+ +Y+P + G F AF+GF  V   L    +       +F  +   +C R+   +   T+   R   ++    CF  +Y+  LLS +GFN  + W SITF+  I    + W+ GY I+ T MI    P I + L AF   VA+L +VF V+L+I 
Sbjct:  317 NVTFKGTGDPTKCREIVEKIFPTKVCSQEPCIFHGIYRPNLRGNFHAFSGFTYVMAYLDFPIEGRKPTRDEFRQRVDAFCKRSWNDISASTSPDSR---SFVSLYCFDGVYIDALLSHFGFNTSDSWRSITFSAKIDGVTVSWAPGYAIDATGMIESTSPKIDLGLLAFTTSVAVLSVVFAVLLAIA 500          

Query:  164 KPAWYSMTIVFFT-LSICGVVIICVLWAFANQLV---YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSG-NYSQQNF 1105
            K  W+   I+F T L + G+V +  +    N+ +   Y YGI++DAGS+ T +++++WP       G V Q+  C     GIS +  +PN A D ++ C+ D+   +IP     ++ VYLGATAGMR++E            +N  A   + E VER L +         +  +IISG  EG   WIT NYL ++L   +  SG      T GALDLGGASTQITFVS +  ES +  +  RLYG +Y+VY+HS+LCYGK Q    +L       I   +       +++PC   G   +   Q +   PCV+G +Y ++NF
Sbjct:   10 KNPWHRPRIIFITVLFVIGIVSMVAIGVVQNKPLHQKYKYGIVLDAGSSHTSVYIYQWPAEKENNTGMVQQMDACNVPGVGISGYSTEPNRAGDSLKSCM-DKARSIIPNHRHPETPVYLGATAGMRLLE-----------MKNAAASEKVLESVERVLQTYPFS----YQGARIISGQEEGAFGWITVNYLNESL---RQASG------TLGALDLGGASTQITFVSGQKQESPDNSIDFRLYGHDYHVYTHSFLCYGKDQ----VLKLSLANEIRPVHTKTETIVVEDPCFHPGYRMNKNFQSVFNSPCVTGLSYPEKNF 302          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQL---VKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI-SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLKPVTEKSSEVV 1764
            N  ++G+ +   C  AV+ +F  S CS + C FN ++QP++ G+F AF+ F  V + L           ++   + A   +   +N P V          KE +    CF   Y+  LL   Y F + NW  I F   I N++ GW+LGYM+N T+MIP E P    +  G +V ++++F V++ +  L A   ++    +P      E++
Sbjct:  301 NFVHMGSGNGTKCHAAVRKVFNDSGCSYSICSFNGIFQPRVEGQFGAFSAFFFVMDFLNLTTLSLDEAKEELGKYCATPWEIIKQNHPNV----------KEKYLAEYCFSGTYILTLLEDGYNFTSHNWQDIKFIKKIGNSDAGWTLGYMLNLTNMIPAESPDTPPLPYGGYVTLMVLFAVMILLLGLLACKVFR----RPTGSAQKEII 497          

Query:  179 SMTIVFFTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVR-LYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSV 1117
            S+ ++ F +    ++ +  L+  A  + Y Y ++IDAGSTS+K+ +FKW +   + NG V +V M K APGIS + + P  A + ++  L D +   +P+  +  + ++L ATAGMR++E             NP     I E +   L   G K+     D++I+SG  EG+ AWIT NYL+       V     S +E  GALDLGGAS QITFV      + +T  R L+G  Y VYS+S+LCYGKS ++ R+ A +          NQ    I+NPC L+         +I T PCV   Y+ +  G+ +
Sbjct:   20 SLLVIIFVV----IITLVALYIVACNVGYLYAVLIDAGSTSSKISVFKWRDWPFQHNGRVEEVYMKKVAPGISSYKDHPEEAFNTLKPTLLDLLQEYVPQESKKSTRLFLAATAGMRLVE-----------LDNPLKADAIMENLRSQLPHVGAKVNNPYSDIRIMSGRDEGINAWITVNYLEKKFGVHGVAPS--SGQEMIGALDLGGASAQITFVPKNPSLAPHTSTRYLFGSEYYVYSYSHLCYGKSASQKRVWAEIIG--------NQSTATINNPCFLQNYELKVKKSEIFTEPCVKSKYAVELIGSEL 308          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGF-NNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVA----ILIVFLVILSI 1689
             +T VGT DPD C++ V+ +F    C+Q+ C F  VY+P + GKF AF+G+A V + L    K          AK  ++C R+   V         E   +    C   +Y+  LLS YGF ++ +W +I F + I    + W+ GY+I+ T MI  E P I + L AFV     + IVF+ +L I
Sbjct:  317 EITLVGTGDPDQCRQFVQKMFPSKACAQSPCMFQGVYRPPLHGKFSAFSGYAFVIDHLNFPTKGQNLTRDAVKAKVDEFCRRDWTQVAQEYPASSLE---FIAGYCQDGVYIDALLSNYGFVDSESWKNIVFASKIAGTTVSWAPGYLIDATGMIDSESPKIDLGLTAFVTSVVILSIVFVALLVI 499          

Query:  266 SYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVR-LYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLP 1126
            +Y ++IDAGSTS+K+ +F W +     NG V ++   K +PGIS + NDP  A + +E  + + +   IP   ++++  YL ATAGMR+++             NP     I EV++  L  TGLK+     DV+++SG  EG+ A+IT NYL     GD+ +S  + + +T G+LDLGGASTQI FVS E + + +T  R L+G +Y +YS+SYLCYGKS AE R+ A   +  + N N   P  PI+NPC+      +     I    CV+G Y+    G+++  P
Sbjct:   44 AYALLIDAGSTSSKLSVFTWKDWPYIDNGYVRELSTDKVSPGISSYKNDPKEAYNKLEPNITNLVKACIPSDQQSRTHQYLAATAGMRLLD-----------LENPLKSEAIIEVLQLNLPRTGLKLGNPYSDVRVMSGRDEGIYAFITVNYLLGKF-GDQQSSP-VDQLQTVGSLDLGGASTQIAFVS-EDVNAPHTSTRGLFGNDYTIYSYSYLCYGKSAAEKRVWA---QIIVNNSNAADPHKPIENPCLNMDKNITIETAPIFDDQCVTGTYASDLVGSALTKP 314          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFAL------VYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGF-NNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVIL 1683
            ++T+ GT DPD C++ V+ +F    CSQT C F ++Y+P + G F+AF+GF        VYN+             D+ A+   +C      V     +K    + +    CF   Y+  LL+ YGF  + +W  ITF + + NA + W++GY I+ T MI    P I +   AF+A ++   +I 
Sbjct:  320 DITFYGTGDPDKCREFVRMMFPSKTCSQTPCMFGDIYRPALRGNFLAFSGFTYSAKFFGVYNKSTT--------RTDYRAQVDKFCKLPYADV-----KKLPGYDKYTYIYCFDGAYIETLLAGYGFEESESWKKITFEDKVNNAIVSWAMGYTIDATGMIESASPQIKLDTNAFIASVVCLSIIF 492          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKET--FGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            YG++ DAGST T +++++WP       G ++QV+ C  S PGIS + ++P GA   ++ CL D+ M ++P   + ++  YLGATAGMR++   N          + KA ++  EV +        +     R  +I++G+ EG   WIT NYL +TL        +   ++T   GALDLGGASTQITF    TIE  NT V  RLYG NY++Y+HSYLCYG++QA  RL    S++   + +P Q    I +PC  KG   S     +   PCV
Sbjct:    3 YGLVFDAGSTHTALYIYRWPADKENGTGIISQVEACTVSGPGISSYADNPAGAGASLKPCL-DKAMKVVPAEQQRETPTYLGATAGMRLLREQN----------STKAEQVFAEVAKAIG-----EYPVDFRGARILTGNEEGSFGWITVNYLLETLVKFSFAEKWEHPQDTEVLGALDLGGASTQITFQPGVTIEDKNTSVFFRLYGTNYSLYTHSYLCYGQTQALKRLPTNCSRSLQGSPSPQQ----ISHPCYPKGYRESITTTDLYDSPCV 257          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWR--CFGFIYVFE-LLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKP--LISMSLGAFVAILIVFLVIL-SIGCLFAII 1710
            +T  GT DPDAC  A++ LF  S      CGFN VYQP + G+F AF+GF   Y+ L  +  +     +   A    +C+ +   V     QKE    N  + R  C    Y    LL  Y FN+  W +I F   + N ++GW+LGYM+N T+MIP E P  +I +    ++A  ++  V+L  I CL  +I
Sbjct:  269 LTVTGTGDPDACSSAIQKLFDFSCGGNRTCGFNGVYQPPVRGQFFAFSGF---YHSLHSLNLTGGLSLSSVNATMEQFCNSSWEKV-----QKEFPAMNRTQLRDACAASSYTLTLLLQGYKFNHTTWLNIHFIRQVTNMDVGWTLGYMLNLTNMIPSETPQRVIGLQRSNWIAATVLLAVMLILIFCLLTVI 453          

Query:  164 KPAWYSMTIVFFT-LSICGVVIICVLWAFANQLV---YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSG-NYSQQNF 1105
            K  W+   I+F T L + G+V +  +    N+ +   Y YGI++DAGS+ T +++++WP       G V Q+  C     GIS +  +PN A D ++ C+ D+   +IP     ++ VYLGATAGMR++E            +N  A   + E VER L +         +  +IISG  EG   WIT NYL ++L   +  SG      T GALDLGGASTQITFVS +  ES +  +  RLYG +Y+VY+HS+LCYGK Q    +L       I   +       +++PC   G   +   Q +   PCV+G +Y ++NF
Sbjct:   10 KNPWHRPRIIFITVLFVIGIVSMVAIGVVQNKPLHQKYKYGIVLDAGSSHTSVYIYQWPAEKENNTGMVQQMDACNVPGVGISGYSTEPNRAGDSLKSCM-DKARSIIPNHRHPETPVYLGATAGMRLLE-----------MKNAAASEKVLESVERVLQTYPFS----YQGARIISGQEEGAFGWITVNYLNESL---RQASG------TLGALDLGGASTQITFVSGQKQESPDNSIDFRLYGHDYHVYTHSFLCYGKDQ----VLKLSLANEIRPVHTKTETIVVEDPCFHPGYRMNKNFQSVFNSPCVTGLSYPEKNF 302          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQL---VKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI-SMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLKPVTEKSSEVV 1764
            N  ++G+ +   C  AV+ +F  S CS + C FN ++QP++ G+F AF+ F  V + L           ++   + A   +   +N P V          KE +    CF   Y+  LL   Y F + NW  I F   I N++ GW+LGYM+N T+MIP E P    +  G +V ++++F V++ +  L A   ++    +P      E++
Sbjct:  301 NFVHMGSGNGTKCHAAVRKVFNDSGCSYSICSFNGIFQPRVEGQFGAFSAFFFVMDFLNLTTLSLDEAKEELGKYCATPWEIIKQNHPNV----------KEKYLAEYCFSGTYILTLLEDGYNFTSHNWQDIKFIKKIGNSDAGWTLGYMLNLTNMIPAESPDTPPLPYGGYVTLMVLFAVMILLLGLLACKVFR----RPTGSAQKEII 497          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMC-KSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIESGN-TKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTP------------IDNPCMLKGDTASYILQKIITI 1069
            YGI++DAGS+ T ++L++WP       G V+Q   C    PGIS+  +D   +   ++ C+ D++   +P    + + ++LGATAGMR++             +N +A   I + ++++L S    +    ++  IISG  EG+  WIT NYL        + + ++     +T G+LDLGGASTQI F + +     +  +V LYG  YNVY+HS+LCYGK++AE ++LA L K+       N P  P             D+ C  K   ASY   K IT 
Sbjct:   61 YGIVLDAGSSRTTVYLYQWPAEKENNTGVVSQTTKCLVKGPGISEMNDD---SWKYLKTCM-DDITKHVPPSQHSSTPIFLGATAGMRLLH-----------IKNEEASNTILQDIQKYLRS----LPFNFQNASIISGQEEGLYGWITVNYLMGNFLEKNMWNAWVHPHGAKTVGSLDLGGASTQIAFTAPDDATGEDLIRVSLYGYEYNVYTHSFLCYGKNEAEKKVLAELVKSSTDWSRVNHPCYPADYSITMAASEIFDSECTKKSTPASYSPAKNITF 324          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPC-SQTNCGFNNVYQPKITGKFIAFAGFALVYNQL-VKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLS-AYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSL--GAFVAILIVFLVILSIGCLFAIIS 1713
            N+T+ G +DP  C+  VK +F    C  + NC F  VYQP ++G+F+A+AGF      L VK   +  + N   ++    +CS+   P  T     E  +++ + + C+   YV  +L+  Y FN+ NW ++ F   +   ++ WSLGYM+ +++MIP E  L+ + +   AF  +L VF  +  I  +F II+
Sbjct:  321 NITFFGGSDPVRCKDLVKRIFDFKSCQGKENCSFEGVYQPPVSGEFMAYAGFYYTAWALDVKGSNTLKQFNTAMLS----FCSK---PWATLKKNYEITEKHLKSY-CYSANYVHTILADGYKFNDDNWENLNFQKEVNQTSIAWSLGYMLAQSNMIPAEAKLLKLPIPNSAFAGLLFVFSALTIITLMFLIIT 506          

Query:  164 KPAWYSMTIVFFT-LSICGVVIICVLWAFANQLV---YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSG-NYSQQNF 1105
            K  W+   I+F T L + G+V +  +    N+ +   Y YGI++DAGS+ T +++++WP       G V Q+  C     GIS +  +PN A D ++ C+ D+   +IP     ++ VYLGATAGMR++E            +N  A   + E VER L +         +  +IISG  EG   WIT NYL ++L   +  SG      T GALDLGGASTQITFVS +  ES +  +  RLYG +Y+VY+HS+LCYGK Q    +L       I   +       +++PC   G   +   Q +   PCV+G +Y ++NF
Sbjct:   10 KNPWHRPRIIFITVLFVIGIVSMVAIGVVQNKPLHQKYKYGIVLDAGSSHTSVYIYQWPAEKENNTGMVQQMDACNVPGVGISGYSTEPNRAGDSLKSCM-DKARSIIPNHRHPETPVYLGATAGMRLLE-----------MKNAAASEKVLESVERVLQTYPFS----YQGARIISGQEEGAFGWITVNYLNESL---RQASG------TLGALDLGGASTQITFVSGQKQESPDNSIDFRLYGHDYHVYTHSFLCYGKDQ----VLKLSLANEIRPVHTKTETIVVEDPCFHPGYRMNKNFQSVFNSPCVTGLSYPEKNF 302          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVY---NQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTI 1551
            N  ++G+ +   C  AV+ +F  S CS + C FN ++QP++ G+F AF+ F  V    N          ++   + A   +   +N P V          KE +    CF   Y+  LL   Y F + NW  I F   +
Sbjct:  301 NFVHMGSGNGTKCHAAVRKVFNDSGCSYSICSFNGIFQPRVEGQFGAFSAFFFVMDFLNLTTLSLDEAKEELGKYCATPWEIIKQNHPNV----------KEKYLAEYCFSGTYILTLLEDGYNFTSHNWQDIKFIKKV 429          

Query:  203 LSICGVVIICVLWAFAN----QLVYS--YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKK--ETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCV 1078
            L++  + I+ ++ + AN    ++ YS  YGI+ DAGST T +FL++WP       G V+Q  MC     GIS ++ +P GA + +  CL D  +  +PK+ +  + VYLGATAGMR++           + +N     +I   V +F+ S         R   IISG+ EG   WIT NYL +          +   K     GA+DLGG+STQI+F   + ++   +   ++LYG+ Y +Y+HSYLC+GK QA  +L A+L KT  AN      L+ +++PC   G   +  L  +   PCV
Sbjct:   16 LAVACMSIVALILSLANYQRVEVPYSTQYGIVFDAGSTHTALFLYQWPGNKENNTGVVSQNLMCDVKGDGISSYVTNPAGAGESLRECL-DVALAAVPKKKQKTTPVYLGATAGMRLL-----------SLQNQTQANIIIAEVSKFIQSYPFD----FRGATIISGTEEGAYGWITINYLLEDFIKYTFDGKWSHPKAGRILGAMDLGGSSTQISFTPKDAVKDPTSAFNLQLYGQKYQLYTHSYLCFGKDQALRKLQAYLQKT--AN------LSTVNHPCYHTGYNLTITLGNLYDSPCV 294          

Query: 1132 FEKFLNVTYVGTADPDACQKAVKNLFLQSPCSQT-NCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSP-PKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLG----AFVAILIVFLVILSIGCLFAI 1707
            F     VT+VGT D   C  + +N+   S C+ + +CGFN VYQP + G F AF+ +   ++ L    ++P P+     ++   ++C+ N   +++ T    +EK+          +     L  Y               + + ++GW+LGYM+N T++IP E+PL    +     A     IVF + LS+  L A+
Sbjct:  300 FNPSAKVTFVGTGDSALCLSSFRNVVNLSDCALSPDCGFNGVYQPPVNGDFYAFSAYFYTFDFLGLAPRTPLPQ----VLSTIDNFCNTNWTTLLS-TYPNVKEKDKQHTHTHTHSLTHCRCLYLY--------------NVSDTDIGWTLGYMLNLTNLIPAERPLAVTGVENKQWAAEVFFIVFGLFLSLIILIAL 478          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKE---GLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSK-----KETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            Y YGI++DAGS+ T MF++KWP       G V+Q   C     GIS +     GA   +E C+ D  +  IPK    ++ +YLGATAGMR+     LN+        PK       V +  L   G K+K     ++   I++G  EG   W+T NYL +      +  GF+       K+T GALD GGASTQITF + E +E+     K+RLYG +Y++Y+ S+LCYG+ Q   +LLA L +T  +N         I +PC       S  L  +   PC +
Sbjct:   40 YMYGIVLDAGSSHTAMFIYKWPANKQNGTGIVSQHSECDVDGGGISSYAGQKGGAARSLEKCM-DHAIQKIPKVRHHQTPIYLGATAGMRL-----LNIS------QPK-------VSDEILKEVGEKLKTYPFSVKGATILTGQEEGAYGWVTVNYLLENF----IKYGFVGHWLSPGKKTVGALDFGGASTQITFETKEKVENVENLMKLRLYGRDYHIYTQSFLCYGRDQMLRKLLAHLVETQGSN-------DAIIHPCYPADYNVSITLDNVFDTPCTA 293          

Query: 1162 GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPT----TQKEREKENWRKWRCFGFIYV-FELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLI--SMSLGAFVAILIVFLVILSI 1689
            G+ +   C   + ++F    C+ + C FN V+QP ++G F+AFA F  +++ L        K        S       A  V   +     QK  E+++  +  C   +++   LL  YGF+  ++  I+F       ++GW+LGYM++ +S++P E   +  ++S GA+  ++ +F V L I
Sbjct:  310 GSGNYQHCLGNMSHIFSFQTCTYSKCSFNGVFQPNVSGNFMAFAAFFYIHSFL--------KSTTGITVTSPSLLEEAAITVCNMSFHEMLQKVPEQQSRLQDYCAATVFMKVLLLKGYGFDRLSFPQISFQKKAGETSVGWALGYMLSLSSLLPAESVSLRKALSPGAWNTLIFLFSVALFI 484          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-----SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNY-LKDTLQGDKVTS-GFMSKKETFGALDLGGASTQITFVSNETIESG--NTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            YGI++DAGS+ T +F+++WP       G + Q  +C      +  GIS + + P+GA + +  C+ D+   ++PK     + + LGATAGMR++E             +  A + +   V   L S     +EG    +IISG  EG   WIT NY L + +Q   +    + +  +  GALDLGGASTQITF++ E ++    +  ++LYG  Y+VYSHSYLCYG+ QA  R L+ L K          P   +DNPC     + +Y L  I   PC S
Sbjct:   42 YGIVLDAGSSHTALFVYEWPAEKQNDTGVIAQRHLCDVDDELAGGGISSYSSSPSGAGESLRACM-DKAKAIVPKDRWADTPLALGATAGMRLLE-----------MSDSVAAKAVLSSVREVLGSYPFSYREG----RIISGQEEGTYGWITANYFLYNFIQFTWLGKWQWTTSTKPIGALDLGGASTQITFMTEEPLQGSPDSLTIQLYGRKYHVYSHSYLCYGRDQAIKRFLSTLYKA--------SPGALVDNPCYPTLYSVAYNLSFIYDSPCTS 297          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFI 1284
            +VT+ GTA+P  C   + ++F  S CS  NC F+ V+QP + G+F+
Sbjct:  309 SVTFRGTANPAECSNTISSIFNFSACSSPNCTFDGVWQPPVRGQFL 354          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLK-DTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSK 961
            YG+++DAGS+ T +F+++WP       G VTQV        GIS + + P  A   +   L +    L+P     ++ + +GATAGMR++             +NP+A   + E V+  L +T           +I++G  EG   W+T NYL+ + LQ D ++       +T GALDLGGASTQI FV      SG  + RLYG ++ V++HSYLCYGK +A  R+ A LS+
Sbjct:    1 YGVVLDAGSSHTSLFVYQWPADKENDTGVVTQVAHIDVEGGGISSYKDHPEMAGQSLVPSLFNATK-LVPPERHHETPISVGATAGMRLLR-----------KQNPEAAERVMESVKTALRATPFLFC----SARILTGQEEGAFGWVTINYLQGNFLQRDWLSWVRPRGAKTVGALDLGGASTQIAFVPAGGALSGTQRFRLYGYDHAVFTHSYLCYGKDEALMRVAATLSR 217          

Query: 1162 GTADPDACQKAVKNLFLQSPCS-QTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKS-RDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYN----ANLGWSLGYMINKTSMIPIE 1617
            G+   D C +AV  +F  S C+ + +C F+ VYQP ++G F+AF+ F  V + L    K   + N D+I    + +C++    V   +  +++  +++    CF   Y+ +LL   Y FN   W +I F   +         GW+LGYM+N+T++IP+E
Sbjct:  279 GSGQADQCAEAVAQIFNYSSCAGRKDCTFDGVYQPPVSGSFMAFSAFYYVMDFL----KLRGEGNVDYIRNVVKRFCNKPWNEVRASSQTEQKHLKSY----CFSANYLLQLLFHGYKFNLSTWMNIKFVKKVEGIQAIGEAGWALGYMLNETNLIPVE 429          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRD-YCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSIGCLFA 1704
            +VT+ GTA+P  C   + ++F  S CS  NC F+ V+QP + G F+AF+ F   Y+ +     + PK   +    + D YC +    +V+ +   +       +  C     +F  +S Y ++  +W +I F        LGW+LG+M+N T+M+P+ K L  +   A V   ++F + + +    A
Sbjct:  106 SVTFRGTANPAECSNTISSIFNFSACSSPNCTFDGVWQPPVRGHFLAFSSF---YHAMAAFNLTNPKPPLNDATNAFDYYCRKTWNELVSRSHPLDSNHCYCYRSTC---KLLFSKVSIYNYDKESWENINFQKEAGGGELGWALGFMLNVTNMVPVGK-LPELYSTAAVGFSLIFTIAIFLAVALA 285          

Query:  785 GALDLGGASTQITFVSNETIESG--NTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVS 1081
            GALDLGGASTQITF++ E ++    +  ++LYG  Y+VYSHSYLCYG+ QA  R L+ L K   +  +       ++NPC     + +Y L  I   PC S
Sbjct:    1 GALDLGGASTQITFMTEEPLQGSPDSLTIQLYGRKYHVYSHSYLCYGRDQAIKRFLSTLYKKASSGAH-------VNNPCYPTLYSVAYNLSFIYDSPCTS 94          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVE-GVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNET--IESGN----TKVRLYGENYNVYSHSYLCYGKSQAEYRLLA 949
            YGI+ DAGST T++ +F + ++      E+T        PG+S + + P  ++  IE  L  +    IP+    ++ V L ATAG+R++                +   ++ E V      +  K+ +    V+I+ G+ E G+++WIT N+L   L+G         + + FG LDLGG STQ+TF+  +   ++S +    T  +++ + + +YSHSYL  G   A   +L 
Sbjct:   63 YGIMFDAGSTGTRIHVFIFKQLNKANLPELTSEVFLSVKPGLSAYADHPEQSVQSIEELLA-KAKKAIPETQWQETPVVLRATAGLRLLP--------------GRKADVLLEQVRNVFDRSPFKVPK--NSVEIMDGANEGGISSWITINFLLGFLRG--------PEDKLFGILDLGGGSTQVTFLPQKQGLLQSASDADVTSFKMFNKTFKIYSHSYLGLGLMSARLAILG 271          

Query:  269 YGIIIDAGSTSTKMFLFKWPEI-----ATRTNGE--------VTQVK--MCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMR--LIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQ--GDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRLYG----------ENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYN--PNQPLTP--IDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            +GI+IDAGS+ +++ +FKW +      AT  + +        + Q K    K  PG+S F   P  A       L D    +IP+   +   V++ ATAGMR++               P+ ++  ++  + +         +++    +++I G  EG+  W+  NYL         +V+  F     TFG +D+GGASTQI F  +++ E    +  +            + ++V+  ++L +G +QA  R LA L  T   N N   N   +   +++PCM +G +  +  +  I     SGNY Q
Sbjct:   10 FGIVIDAGSSGSRIHVFKWQDTESLLHATNQDSQSILQSVPHIHQEKDWTFKLNPGLSSFEKKPQDAYKSHIKPLLDFAKNIIPESHWSSCPVFIQATAGMRLL---------------PQDIQSSILDGLCQGLKHPAEFLVEDCSAQIQVIDGETEGLYGWLGLNYLYGHFNDYNPEVSDHF-----TFGFMDMGGASTQIAFAPHDSGEIARHRDDIATIFLRSVNGDLQKWDVFVSTWLGFGANQARRRYLAQLINTLPENTNDYENDDFSTRNLNDPCMPRGSSTDFEFKDTIFHIAGSGNYEQ 298          

Query: 1159 VGTADPDACQKAVKNLFLQS-PCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKS-RDYCSRNAPPVVTPTTQKEREK--ENWRKWRCFGFIYVFELLSAYGFNNP 1518
             G+ + + C K++  L L++ PC    C FN V+ P+I      F G +  +     VFK   + N D  +KS R++C+ N   ++  + +       EN+ K  CF   +V  +L   GF+ P
Sbjct:  291 AGSGNYEQCTKSIYPLLLKNMPCDDEPCLFNGVHAPRIDFANDKFIGTSEYWYTANDVFKLGGEYNFDKFSKSLREFCNSNWTQILANSDKGVYNSIPENFLKDACFKGNWVLNILHE-GFDMP 413          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQI----TFVSNETIESGNTKVRL-YG-ENYNVYSHSYLCYGKSQAEYRLLAFL 955
            + Y I+IDAGST +++ ++K+ ++ T     + + K     PG+S F  D  GA + ++  L    M  +P + R+ + V + ATAG+R++              + K+ +++  V +         + EG   V I+ G  EGV AWITTNYL   +  +        K  T    DLGG STQI    TF  NE +  G  K  L +G ENY +Y  S+L YG  +   ++ + L
Sbjct:   91 HKYVIMIDAGSTGSRVHIYKF-DVCTSPPTLLDE-KFDMLEPGLSSFDTDSVGAANSLDPLLK-VAMNYVPIKARSCTPVAVKATAGLRLL-------------GDAKSSKILSAVRDHLEKDYPFPVVEG-DGVSIMGGDEEGVFAWITTNYLLGNIGANG------PKLPTAAVFDLGGGSTQIVFEPTFPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVL 304          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQV---KMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRL-IFEVVERFLLSTG---LKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPC-------MLKGDTASYILQ 1054
            Y ++ DAGS+ T+  ++K  +  T    +VTQ+   K  K+ PG+S F   P G    ++  + +    ++P + + ++ VYL ATAGMR++               P   ++ +   V  FL  +       K+G  + K+ISG  E    W+T N+L   L G+  T         +G LD+GGASTQ  F +N T +     + L      +Y+HSYL YG+ +A  R + FL    + N   N+ +  I NPC        ++ D A Y+++
Sbjct:   30 YAVLFDAGSSGTRCKVYKLIQRQTLHVRDVTQLNVPKPNKAKPGLSSFGESPAGVGPYLQTLI-EGAKKVVPVQYQAQTPVYLFATAGMRLL---------------PVDQKIAVINEVNNFLRDSKKSPFAFKKG--NAKVISGIDEATYDWVTVNFLMGALTGESDTE--------YGVLDMGGASTQNAFDTNNT-QHITVVLDLTKGMLPLYAHSYLGYGEQEARKRFIRFL----VNNRRHNRKV--ITNPCYNSNFEKRVEVDGAEYLMR 272          

Query: 1018 HAKGRYSFIHFTKNNNHSLRIWKLFPTEFRNQR*FTRFFEKFLNVTYV-----GTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPK-DNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMI 1608
              + R  FI F  NN    R     P    N       FEK + V        G  +P  C   +K+LF      + NC F+   QP++ GKF +F+ F   + +   V K+  + D      K   +C R+        T+KE   + +   RCF   +++ +L+  G+   N   +    +I   +L W+LG M++   ++
Sbjct:  227 EQEARKRFIRFLVNNRRHNRKVITNPCYNSN-------FEKRVEVDGAEYLMRGGFNPQMCHMIIKSLFFCLSSKKDNCPFHQ--QPRLKGKFYSFSLFTYAFRETGVVSKNGERIDMETLKRKMLSFCGRD-------LTEKELANK-YTTPRCFQLNFIYSMLTD-GYRVDNSFELYNGESINGLDLNWTLGAMLSALKVL 411          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK---SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVER--------FLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITF-VSNETIESGNTKVRLYGENYNVYSHSYLCYGKSQAE 934
            Y ++ DAGS+ T+  ++K     +    +V+Q+K+ K   + PG+S F + P+G    ++  + D  +  +P + ++++ VY+ ATAGMR++              + KA  +I  V +         FL  TG        ++K+ISG  E +  W+T N+L   L G+  T         +GAL++GGAS+Q  F V    + +    +R +G    +Y+HSYL YG+S+A 
Sbjct:    1 YAVMFDAGSSGTRCKVYKLQTRHSLRISDVSQIKVPKPNKATPGLSFFGDSPSGVGPYLQPLI-DAAINAVPSQYQSQAPVYVFATAGMRLLP-------------DNKATAVIRAVEQMLSNSSKSPFLFQTG--------NIKVISGKDEAIYDWVTVNFLMGVLTGESSTE--------YGALEMGGASSQNAFEVPVNQLHTAILNLR-HGTR-RLYAHSYLGYGESEAR 202          

Query: 2737 IGGPGIIVQLDKCKFGKRV--DGAWVFGGVEVAAARKCFSKVVESRDQDTLNDLIMQYV*LGSIVVSVGYKVYNKFKKNDEFE*HCVKNSIHFVNLEGFHTKHFEETW 3054
            IGGPG +VQ+D+ K G R    G WVFGG+E A  +  F   V  R  +TL  +I +     S++VS  ++ Y+K ++ + +    V +S  FVN +G+HT   E  W
Sbjct:    3 IGGPGKLVQIDETKVGHRKCHRGQWVFGGIEEAGWKVVFV-AVPDRTGNTLLPIIKE----SSVIVSYCWRSYSKLEE-EGYNQQPVNHSEEFVNEQGWHTNKIEGHW 104          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSA-PGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNE--TIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            Y YGI++DAGS+ T +++++WP       G V Q   C+ A  GIS +   P  A + +  CL  E    IP+++  ++ +YLGATAGMR+++             N  A   +F+ VE+ L           +  ++++G  EG   W+T NYL      D++T G     ET GALDLGGASTQI+FVS+E    ES +  V  RLYG +Y +Y+HS+LCYGK QA    LA  +K        N   T I +PC  KG   +     +   PCVS    Q
Sbjct:   47 YKYGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLK-EAKENIPQKMHPETPLYLGATAGMRLLK-----------LENSSASDEVFKAVEKTLRGFPF----SYQGARLLAGQEEGAFGWVTVNYLD-----DRLTQGL----ETTGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQALRLALAHQTKV-------NSGPTAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQ 297          

Query: 1156 YVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWR---CFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK----PLISMSLGAFVAILIVFLVILSIGCLFAI 1707
            ++G  +   CQ+ +K++F  + C  + C FN ++QP + G+F AF+ +  V N L     S P      + K  DYC+       TP TQ ++E +   K+    CF   Y+  L+   Y F +  + SI +   I N++ GW+LGYM+N T+MIP E     PL   S  + V ++ + L ++ I  L+++
Sbjct:  305 HLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGIFQPPLQGQFGAFSAYFFVMNFLNLTDTSVPLKTV--MQKLSDYCA-------TPWTQIKKEHDIPLKYLAEYCFSGTYILTLMMEGYNFTSETYSSIKYIQKIKNSDAGWTLGYMLNLTNMIPAEAPDSPPLTYTSYVSVVTVMAILLFVIFILILYSL 487          

Query:  266 SYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSA-PGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQ-----GDKVTSGFMSKKETFGALDLGGASTQITFVSNE--TIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            +YGI++DAGS+ T +++++WP       G V Q   C+ A  GIS +   P  A + +  CL  E    IP+++  ++ +YLGATAGMR+++             N  A   +F+ VE+ L           +  ++++G  EG   W+T NYL D L      G K TS     +   GALDLGGASTQI+FVS+E    ES +  V  RLYG +Y +Y+HS+LCYGK QA    L+           P    T I +PC  KG   +     +   PCVS    Q
Sbjct:   28 TYGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLK-EAKENIPQKMHPETPLYLGATAGMRLLK-----------LENSSASDEVFKAVEKTLRGFPFS----YQGARLLAGQEEGAFGWVTVNYLDDRLTQVSMGGFKYTS-VHGNESAKGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQALRLALS----------GP----TAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQ 283          

Query: 1156 YVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQ-----KEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK----PLISMSLGAFVAILIVFLVILSIGCLFAI 1707
            ++G  +   CQ+ +K++F  + C  + C FN ++QP + G+F AF+ +  V N L     S P      + K  DYC+       TP TQ     K      +    CF   Y+  L+   Y F +  + SI +   I N++ GW+LGYM+N T+MIP E     PL   S  + V ++ + L ++ I  L+++
Sbjct:  291 HLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGIFQPPLQGQFGAFSAYFFVMNFLNLTDTSVPLKTV--MQKLSDYCA-------TPWTQVCAYFKHDIPLKYLAEYCFSGTYILTLMMEGYNFTSETYSSIKYIQKIKNSDAGWTLGYMLNLTNMIPAEAPDSPPLTYTSYVSVVTVMAILLFVIFILILYSL 475          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSA-PGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQ-----GDKVTS--GFMSKKETFGALDLGGASTQITFVSNE--TIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            YGI++DAGS+ T +++++WP       G V Q   C+ A  GIS +   P  A + +  CL  E    IP+++  ++ +YLGATAGMR+++             N  A   +F+ VE+ L   G       +  ++++G  EG   W+T NYL D L      G K TS  G  S  ET GALDLGGASTQI+FVS+E    ES +  V  RLYG +Y +Y+HS+LCYGK QA  RL              + P T I +PC  KG   +     +   PCVS    Q
Sbjct:   31 YGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLK-EAKENIPQKMHPETPLYLGATAGMRLLK-----------LENSSASDEVFKAVEKTL--RGFPFS--YQGARLLAGQEEGAFGWVTVNYLDDRLTQVSMGGFKYTSVHGNESGLETTGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQA-LRL--------------SGP-TAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQ 286          

Query: 1156 YVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQ---LVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELL-SAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK----PLISMSLGAFVAILIVFLVILSIGCLFAI 1707
            ++G  +   CQ+ +K++F  + C  + C FN ++QP + G+F  F  F  +Y Q   ++ +  SP +     I K  D       P+             +    CF   Y+  L+   Y F +  + SI +   + + + GW+LGYM+N T+MIP E     PL   S  + V ++ + L ++ I  L+++
Sbjct:  294 HLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGIFQPPLQGQFGTFVLF--IYTQRFLIISIHFSPSQRLQ--IKKEHDI------PL------------KYLAEYCFSGTYILTLMMEGYNFTSETYSSIKYIQKV-SCDAGWTLGYMLNLTNMIPAEAPDSPPLTYTSYVSVVTVMAILLFVIFILILYSL 462          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSA-PGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNE--TIESGNTKV--RLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            Y YGI++DAGS+ T +++++WP       G V Q   C+ A  GIS +   P  A + +  CL  E    IP+++  ++ +YLGATAGMR+++             N  A   +F+ VE+ L           +  ++++G  EG   W+T NYL      D++T G     ET GALDLGGASTQI+FVS+E    ES +  V  RLYG +Y +Y+HS+LCYGK QA    LA  +K+      P    T I +PC  KG   +     +   PCVS    Q
Sbjct:   47 YKYGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLK-EAKENIPQKMHPETPLYLGATAGMRLLK-----------LENSSASDEVFKAVEKTLRGFPF----SYQGARLLAGQEEGAFGWVTVNYLD-----DRLTQGL----ETTGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQALRLALAHQTKS-----GP----TAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQ 295          

Query: 1156 YVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKE---NWRKWRCFGFIYVFEL-LSAYGFNNPNWHSITFTNTI 1551
            ++G  +   CQ+ +K++F  + C  + C FN ++QP + G+F AF+ +  V N L     S P      + K  DYC+       TP TQ ++E +    +    CF   Y+  L +  Y F +  + SI +   +
Sbjct:  303 HLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGIFQPPLQGQFGAFSAYFFVMNFLNLTDTSVPLKTV--MQKLSDYCA-------TPWTQIKKEHDIPLKYLAEYCFSGTYILTLMMEGYNFTSETYSSIKYIQKV 429          

Query:  263 YSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCK-SAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSK-----KETFGALDLGGASTQITFVSNETIESGNT--KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPID------------NPCMLKGDTASYILQKIITIPCVSGNYSQ 1096
            + YGI++DAGS+ T +F+++WP       G VTQ   C     GIS +      A + +  CL D+ +  IPK     + VYLGATAGMR+     LN+       NPK    I + V   + S   K  EG     I+SG  EG   W+T NYL +      +  GF+ +     + T GALDLGGASTQITF + E +E      ++RLYG  Y++Y+HS+LCYG +Q   R+LA L K+     +   P  P D            +PC  +     Y  +  +T+   SGNY Q
Sbjct:   38 FMYGIVLDAGSSHTALFIYRWPADKQNGTGVVTQHAECHVQGEGISSYAGQKGEAGESLVACL-DQAVRDIPKDKHQLTPVYLGATAGMRL-----LNIS------NPKQSDQILKEVGDKIKSYPFKF-EG---AAILSGQEEGAYGWVTVNYLLENF----IKYGFIGRWMSPGRATVGALDLGGASTQITFATQERVEGKQNMMEMRLYGHKYSLYTHSFLCYGINQVYNRMLAHLVKSQGYVQSVTNPCYPPDVNTTLKMKDVFSSPCTEEHRPKPYNPEGTLTVKG-SGNYQQ 314          

Query: 1150 VTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFEL-LSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEK 1620
            +T  G+ +   C++ + N+F    C  + C FN + QP +TG F+AF+ F  V++ L K+   P          ++  CS     +   + Q   +  +W  + C   +++  L L  Y F+N  +  I+F     + ++GW+LGY++N ++++P EK
Sbjct:  304 LTVKGSGNYQQCEENMSNMFSFEDCPFSQCSFNGISQPNVTGNFMAFSTFFYVHSSLRKLTGKPVNTPQQLQEAAQTTCSMTLSQM---SNQIPDQGPHWMNY-CTASVFIKTLVLRGYAFDNSTFPQISFQKKAGDTSVGWALGYILNLSNLLPAEK 457          

Query:  131 MKKIEKLKDIPKPAWYSMTIVFFTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLPDSLKN 1141
            MKKIEKLKDIPKPAWYSMTIVF TLSICG+VIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE           YRNPKAMRLIFEVVERFLLSTGLKMK+GLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSN TIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLPDSLKN
Sbjct:    1 MKKIEKLKDIPKPAWYSMTIVFLTLSICGIVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE-----------YRNPKAMRLIFEVVERFLLSTGLKMKDGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNGTIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLPDSLKN 326          

Query: 1144 LNVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLKPVTEKSSEVVSLNPKVNNISDDLTNKV 1815
            LNVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLKPVTEKSSEVVSLNPKVNNISDDLTNKV
Sbjct:  329 LNVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSIGCLFAIISYKWYWLKPVTEKSSEVVSLNPKVNNISDDLTNKV 552          

Query:  146 KLKDIPKPAWYSMTIVFFTLSICGVVIICVLWAFANQLVYSYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNT-KVRLYGENYNVYSHSYLCYGKSQAEYRLLAFLSKTWIANYNPNQPLTPIDNPCMLKGDTASYILQKIITIPCVSGNYSQQNFGTSVDLP 1126
            K K+     W  + IV F LS+CG++ +  ++      +++Y +IIDAGSTS+K++L+ W       N +V QV MCK+ PGIS F  +PN + +GI+ CL+ +++PLIP  +R K+FVYLGATAGMR++           +  NP A + I   +   L  + LK+   + D+ II+G+ EG+  W T N+L   L  + V      K    GALD+GGASTQITF+ N       T K++LYG +Y++YSHSYLCYGKSQAEYR LA L +  I N+  N     I NPCM + ++ +Y  + I  +PCV G ++  ++G  V  P
Sbjct:   95 KTKNYQTLMWKPLAIVAFFLSLCGIIALITIYVINLSSIFTYSVIIDAGSTSSKIYLYYWESNKYINNADVLQVAMCKADPGISSFYTNPNKSYNGIKNCLDTKIIPLIPAEMRKKTFVYLGATAGMRML-----------SLNNPNASQQIMYFIRNSLTKSPLKVNNSISDIAIITGAQEGLYGWTTVNFLLKNLPKNIV-----KKPNVIGALDMGGASTQITFIDNSPNNWTETIKLKLYGNSYSIYSHSYLCYGKSQAEYRFLAELIE--IENFTTN-----ISNPCMSETESITYGAKDIFNVPCVMGKFALDHYGHEVIPP 399          

Query: 1147 NVTYVGTADPDACQKAVKNLFLQSPCSQTNCGFNNVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADF---IAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIPIEKPLISMSLGAFVAILIVFLVILSIGCLFA 1704
            N+T+ GT++   C   V++LF +S C+  +C FN VYQP I+GKF AF+ +      L+K   +   +N DF     + ++ C+           +     + W KWRCF  +++ ++L   GFN  NW +I F + I +AN+GW LG++ +KTS++P E+  + +    F  +L V LVI+     F 
Sbjct:  408 NITFKGTSNYTYCNSTVQHLFNKSRCAFGSCPFNGVYQPPISGKFGAFSAY-----NLIKTILNEKNENLDFEKYKTRMKNLCNSKYNSTFVLNGE-----DKWTKWRCFDIVFMIQMLINLGFNESNWSNIEFIDKIGDANVGWGLGFIFDKTSILPKEQHFLPIENYLFGILLAVLLVIMCFAVAFT 586          

Query: 2734 KNVCSSKFVRKQH*IGGPGIIVQLDKCKFGKR-------VDGAWVFGGVEVAAARKCFSKVVESRDQDTLNDLIMQYV*LGSIVVSVGYKVYNKFKKNDEFE*HCVKNSIHFVNLEGFHTKHFEETWN 3096
            K VC S   R+   IGGPG++VQLD+ KFGKR       V+G WVF GVE    RKCF+ +V+ RD DT+N LI++Y   GS VV+ G+K  + FK N  F  H   +S+ FVN EGF+T   + T+N
Sbjct:   31 KKVCES-VSREDLRIGGPGVLVQLDESKFGKRKYNLGHRVEGTWVFAGVEKTPERKCFAVIVDKRDADTVNFLILKYALPGSTVVTDGWKGNDTFKNNINFTHHWANHSVTFVNNEGFNTYTIDGTFN 157          

Query:  266 SYGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSAPGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGNTKVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            ++GI+IDAGS  T+ +L+KW +  T TN EV+++  C +      +  + N   + +  C+   ++ L  + ++ K  +YL ATAGMRI+E  N  L            +++F  ++      G   K     V I+ G  EG++ W T NYLK+T+  +        +  TFG LDLGG+STQI F +    ++G+  V L+   Y +YS SYLCYG +    R L
Sbjct:   93 NFGIVIDAGSGGTRAYLYKWYDENTNTNDEVSEIGNCVTDKLQILYFQNRN---EDLMKCIKSLLLKL--RAVKFKPPIYLAATAGMRILEIENKTL-----------TKVMFNEIKSLFYVLGWNFKF----VGILKGYYEGISGWTTVNYLKNTIGKNSTVRK--DRFSTFGVLDLGGSSTQIAFET----KTGDP-VILFTRKYLLYSRSYLCYGVNMFRIRYL 292          

Query: 1249 NVYQPKITGKFIAFAGFALVYNQLVKVFKSPPKDNADFIAKSRDYCSRNAPPVVTPTTQKEREKENWRKWRCFGFIYVFELLSAYGFNNPNWHSITFTNTIYNANLGWSLGYMINKTSMIP 1611
            +V Q     +F+A A FA     L K ++   K N+ F+  +  +C+ +   +     +  +  +N+    C    ++  L   YG N  N+ ++ F N I   N GW+LGYMI +T  IP
Sbjct:  359 DVIQVDKKMRFVAVAVFAYYNAFLTKYYRMTGKYNS-FVQATGLFCTEDYATLDAKYGKDAKFAQNY----CLVGNFIIVLFQMYGINASNFDNVIFANKIRGQNTGWNLGYMIKQTKDIP 474          

Query:  269 YGIIIDAGSTSTKMFLFKWPEIATRTNGEVTQVKMCKSA-PGISDFINDPNGAIDGIEMCLNDEMMPLIPKRLRTKSFVYLGATAGMRIIE*MNLNLK*FYAYRNPKAMRLIFEVVERFLLSTGLKMKEGLRDVKIISGSVEGVAAWITTNYLKDTLQGDKVTSGFMSKKETFGALDLGGASTQITFVSNETIESGN-TKVRLYGENYNVYSHSYLCYGKSQAEYRLL 946
            Y I+ DAGST T++ ++K+      T   V   ++ +   PG+S + N P     GI   L       IPK    ++++ L ATAG+R++                +  + + + V+  L ++G ++      V I+SG  EG+ +W+T N+L   ++           + +FG +DLGG S QITFV +  +      KV+L      +YSHSYL  G   A Y +L
Sbjct:   28 YAIVFDAGSTGTRIHVYKFRYSQNETYPYVLVDELFEEVKPGVSSYANKPADVKKGIIQLLQSAKRK-IPKPFWVRTWMTLKATAGLRLL--------------GEQQAQTLLDEVKSVLNTSGFQLMPN--GVSIMSGLDEGILSWVTVNFLLQRVR---------QPRHSFGTIDLGGGSMQITFVPDHNVSRRFLQKVKLGNSKKGIYSHSYLGLGLMSARYCIL 229