Leucine--tRNA ligase, cytoplasmic
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024910 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Human
Match: LARS1 (leucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6512]) HSP 1 Score: 1184.09 bits (3062), Expect = 0.000e+0 Identity = 609/1199 (50.79%), Postives = 820/1199 (68.39%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETP---VAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ +VFE N + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E +++ + I +K KGKKSKA AK+G KYQW IM+ G++DEEI KF+E ++W+ Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC ++AARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ Y I D VLPFEPV VI+IP +G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ +I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E WK T CL + TF +E RRNFEA L L E+ACSR+YGLGT +PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG+L G++ + GI MT + W+YV + + KLD L++EF +WYPVDLRVSGKDLVPNHL+YYL+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP S +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G V+E L +YL ++H+ R + ++ + I++AK+YPPWQ + L L GKLPDNK + S L PELKK MKK M + I+ + + L+ E DEK+V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F + P V +V++VNP +G S +IEI GD+ ++ RR+ I+D + V+L F D R +P+ + + PI +A F+V I + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAE-SPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAK--EKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQL-EFDEKAVLMENIVYLTNSLELE--HIEVKFASEAED-KIREDCCPGKPLNVFRI--------EPGV---------------SVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Human
Match: LARS1 (leucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6512]) HSP 1 Score: 1132.86 bits (2929), Expect = 0.000e+0 Identity = 583/1148 (50.78%), Postives = 785/1148 (68.38%), Query Frame = 3
Query: 318 MNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETP---VAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
MNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E +++ + I +K KGKKSKA AK+G KYQW IM+ G++DEEI KF+E ++W+ Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC ++AARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ Y I D VLPFEPV VI+IP +G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ +I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E WK T CL + TF +E RRNFEA L L E+ACSR+YGLGT +PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG+L G++ + GI MT + W+YV + + KLD L++EF +WYPVDLRVSGKDLVPNHL+YYL+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP S +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G V+E L +YL ++H+ R + ++ + I++AK+YPPWQ + L L GKLPDNK + S L PELKK MKK M + I+ + + L+ E DEK+V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F + P V +V++VNP +G S +IEI GD+ ++ RR+ I+D + V+L F D R +P+ + + PI +A F+V I + NG+ IG+
Sbjct: 1 MNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAE-SPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAK--EKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQL-EFDEKAVLMENIVYLTNSLELE--HIEVKFASEAED-KIREDCCPGKPLNVFRI--------EPGV---------------SVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGD 1115
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Human
Match: LARS1 (leucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6512]) HSP 1 Score: 368.237 bits (944), Expect = 1.398e-114 Identity = 205/507 (40.43%), Postives = 303/507 (59.76%), Query Frame = 3
Query: 2229 IWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP S +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G V+E L +YL ++H+ R + ++ + I++AK+YPPWQ + L L GKLPDNK + S L PELKK MKK M + I+ + + L+ E DEK+V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F + P V +V++VNP +G S +IEI GD+ ++ RR+ I+D + V+L F D R +P+ + + PI +A F+V I + NG+ IG+
Sbjct: 1 MWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQL-EFDEKAVLMENIVYLTNSLELE--HIEVKFASEAED-KIREDCCPGKPLNVFRI--------EPGV---------------SVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGD 478
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Human
Match: LARS1 (leucyl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:6512]) HSP 1 Score: 157.147 bits (396), Expect = 1.441e-43 Identity = 73/116 (62.93%), Postives = 90/116 (77.59%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPE 512
RKGTAK++ +K IE Q++W+ +VFE N + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+
Sbjct: 4 RKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPD 119
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Match: lars-1 (Leucine--tRNA ligase [Source:UniProtKB/Swiss-Prot;Acc:Q09996]) HSP 1 Score: 1076.62 bits (2783), Expect = 0.000e+0 Identity = 563/1108 (50.81%), Postives = 738/1108 (66.61%), Query Frame = 3
Query: 186 KLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKT---EINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKH--GVLICVERAARNMAYQEILTDQPGEV---IILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESK-PNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMG---DYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXH------NAAIIWIAKSYPPWQMSILDSLIDMSD-KEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECS-DEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFS 3449
K+ +++IE + Q+ WE+ K FEA+ D K KY VTFP+PYMNG LHLGH FS SKCEF+ G++RL+GK L+ FGFHCTGMPIK+ ADKLKREM+ FG+PP FPE EE + EI +K KGKKSK VAK+G KYQWQIM+ G+ DEEIK+F++ ++W+ Y+PP I ++K++G+K DWRRSFITTD NP++DSFVRWQF L+ KI FGKR TI+SP D QPCMDHDR+SGEGVGPQEYTLIK+K+ P PQ L IK+D++LVAATLRPETMYGQTNC++HP I+Y +T++ V + R+AR M+YQ LT + G+V + L K G +++G L APL Y+ +Y LPM +IK +KGTG+VTSVPSDSPDD+AAL DLK+K+ R Y + D VLPFEPV +I I G AV+ KI+SQN+ DKL EAK++ Y GFY G +++GKYAG K++IQ DL GLA Y EPE++V+SRSG ECVVALCDQWYLNY + +WK+ K L + TF+DE RR E ++ LHEYACSRSYGLGT++PWD QYL+ESLSDSTIY AYYTVAH+LQ G+ DG S V +GI MT +W YV + + + P KL LR+EF YWYP+D+R SGKDL+ NHLTY LFNH AIWP ++ + WPK IRANGHLLLNNEKMSKSTGNF+T+ EAIEK+SADGMR++ ADAGD +EDANFV MADA +LRL++ IEW+KE++E + + +D VFAN +N I TE NY+ +K L+ GF E+Q+IRD YRE C G L+ F+E Q LILSPICPHI +YIW +L K I+N WP VDEKL+ R++ EFR + K A+I++AK YPPWQ +ILD L + G LPDNK+++ + + LKK KKAM +Q I+ + ++ + +P +D+ S++ N ++ L+LD ++ ++++DE D + ++ P+ P + F + P V R N++ V +VN D S
Sbjct: 10 KVAQLQEIEKSIQELWESKKAFEADA--RDDGKPKYLVTFPFPYMNGRLHLGHTFSASKCEFAAGFQRLQGKEVLFPFGFHCTGMPIKACADKLKREMQDFGYPPNFPEDVVEEVKEEVSAVDEIIKDKSKGKKSKLVAKTGNAKYQWQIMKSLGLCDEEIKEFSDPNHWLYYFPPHCIADLKKMGLKADWRRSFITTDVNPYFDSFVRWQFNLLRAAKKIDFGKRYTIYSPKDGQPCMDHDRASGEGVGPQEYTLIKLKVLDPKPQALSHIKEDIYLVAATLRPETMYGQTNCYLHPDIQYSVFYATENEKQVFVATARSARIMSYQG-LTKENGKVNYVLGLEKIAGSKILGAPLSAPLAKYERVYALPMLTIKDDKGTGVVTSVPSDSPDDFAALSDLKKKKPLREKYGLTDEMVLPFEPVPIIKIEGLGDLAAVEMCSRLKIESQNEKDKLEEAKKEVYLKGFYDGVMLVGKYAGKKTADVKKVIQDDLTAEGLATKYVEPEKKVMSRSGDECVVALCDQWYLNYGEAEWKAAAKKVLEPLRTFNDETRRGLETTVDWLHEYACSRSYGLGTKLPWDTQYLIESLSDSTIYNAYYTVAHLLQQGAFDG-SVVGPAGIKADQMTDASWSYVFLGEIYDSKTM-PVEEEKLKSLRKEFMYWYPIDMRASGKDLIGNHLTYLLFNHAAIWPTDTSK-WPKGIRANGHLLLNNEKMSKSTGNFMTLEEAIEKFSADGMRLSLADAGDGLEDANFVYAMADAAILRLFTMIEWIKEMIEQRDAGLLRKDAKKFADRVFANEMNSLIAATEQNYEATNFKDALKTGFFEYQAIRDTYRELCAGIDEPMSESLVFRFIETQMLILSPICPHIAEYIW-QLLGKDGLIVNAPWPTVDPVDEKLAIGARFITESLAEFRARLKTYMTPKKKALKEIPEVPTEAVIYVAKEYPPWQKTILDILEKQAKANNGALPDNKAISQLIGKEESLKKFAKKAMPFVQMIKERFEQKGVSALASSSP-VDQTSILNENIDFIMNALDLD--RVTIRHTDEEGIDANIVETTVPLVPMLNFT------PNRPTIKLVARNVQICNAMFDVDVPIVNGDSVS 1101
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Match: lars-1 (Leucine--tRNA ligase [Source:UniProtKB/Swiss-Prot;Acc:Q09996]) HSP 1 Score: 1076.62 bits (2783), Expect = 0.000e+0 Identity = 563/1108 (50.81%), Postives = 738/1108 (66.61%), Query Frame = 3
Query: 186 KLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKT---EINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKH--GVLICVERAARNMAYQEILTDQPGEV---IILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESK-PNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMG---DYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXH------NAAIIWIAKSYPPWQMSILDSLIDMSD-KEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECS-DEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFS 3449
K+ +++IE + Q+ WE+ K FEA+ D K KY VTFP+PYMNG LHLGH FS SKCEF+ G++RL+GK L+ FGFHCTGMPIK+ ADKLKREM+ FG+PP FPE EE + EI +K KGKKSK VAK+G KYQWQIM+ G+ DEEIK+F++ ++W+ Y+PP I ++K++G+K DWRRSFITTD NP++DSFVRWQF L+ KI FGKR TI+SP D QPCMDHDR+SGEGVGPQEYTLIK+K+ P PQ L IK+D++LVAATLRPETMYGQTNC++HP I+Y +T++ V + R+AR M+YQ LT + G+V + L K G +++G L APL Y+ +Y LPM +IK +KGTG+VTSVPSDSPDD+AAL DLK+K+ R Y + D VLPFEPV +I I G AV+ KI+SQN+ DKL EAK++ Y GFY G +++GKYAG K++IQ DL GLA Y EPE++V+SRSG ECVVALCDQWYLNY + +WK+ K L + TF+DE RR E ++ LHEYACSRSYGLGT++PWD QYL+ESLSDSTIY AYYTVAH+LQ G+ DG S V +GI MT +W YV + + + P KL LR+EF YWYP+D+R SGKDL+ NHLTY LFNH AIWP ++ + WPK IRANGHLLLNNEKMSKSTGNF+T+ EAIEK+SADGMR++ ADAGD +EDANFV MADA +LRL++ IEW+KE++E + + +D VFAN +N I TE NY+ +K L+ GF E+Q+IRD YRE C G L+ F+E Q LILSPICPHI +YIW +L K I+N WP VDEKL+ R++ EFR + K A+I++AK YPPWQ +ILD L + G LPDNK+++ + + LKK KKAM +Q I+ + ++ + +P +D+ S++ N ++ L+LD ++ ++++DE D + ++ P+ P + F + P V R N++ V +VN D S
Sbjct: 10 KVAQLQEIEKSIQELWESKKAFEADA--RDDGKPKYLVTFPFPYMNGRLHLGHTFSASKCEFAAGFQRLQGKEVLFPFGFHCTGMPIKACADKLKREMQDFGYPPNFPEDVVEEVKEEVSAVDEIIKDKSKGKKSKLVAKTGNAKYQWQIMKSLGLCDEEIKEFSDPNHWLYYFPPHCIADLKKMGLKADWRRSFITTDVNPYFDSFVRWQFNLLRAAKKIDFGKRYTIYSPKDGQPCMDHDRASGEGVGPQEYTLIKLKVLDPKPQALSHIKEDIYLVAATLRPETMYGQTNCYLHPDIQYSVFYATENEKQVFVATARSARIMSYQG-LTKENGKVNYVLGLEKIAGSKILGAPLSAPLAKYERVYALPMLTIKDDKGTGVVTSVPSDSPDDFAALSDLKKKKPLREKYGLTDEMVLPFEPVPIIKIEGLGDLAAVEMCSRLKIESQNEKDKLEEAKKEVYLKGFYDGVMLVGKYAGKKTADVKKVIQDDLTAEGLATKYVEPEKKVMSRSGDECVVALCDQWYLNYGEAEWKAAAKKVLEPLRTFNDETRRGLETTVDWLHEYACSRSYGLGTKLPWDTQYLIESLSDSTIYNAYYTVAHLLQQGAFDG-SVVGPAGIKADQMTDASWSYVFLGEIYDSKTM-PVEEEKLKSLRKEFMYWYPIDMRASGKDLIGNHLTYLLFNHAAIWPTDTSK-WPKGIRANGHLLLNNEKMSKSTGNFMTLEEAIEKFSADGMRLSLADAGDGLEDANFVYAMADAAILRLFTMIEWIKEMIEQRDAGLLRKDAKKFADRVFANEMNSLIAATEQNYEATNFKDALKTGFFEYQAIRDTYRELCAGIDEPMSESLVFRFIETQMLILSPICPHIAEYIW-QLLGKDGLIVNAPWPTVDPVDEKLAIGARFITESLAEFRARLKTYMTPKKKALKEIPEVPTEAVIYVAKEYPPWQKTILDILEKQAKANNGALPDNKAISQLIGKEESLKKFAKKAMPFVQMIKERFEQKGVSALASSSP-VDQTSILNENIDFIMNALDLD--RVTIRHTDEEGIDANIVETTVPLVPMLNFT------PNRPTIKLVARNVQICNAMFDVDVPIVNGDSVS 1101
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Match: Y105E8A.20 (pep chromosome:WBcel235:I:14486890:14495252:-1 gene:WBGene00013678.1 transcript:Y105E8A.20a.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y105E8A.20) HSP 1 Score: 55.4546 bits (132), Expect = 1.766e-7 Identity = 33/94 (35.11%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 2151 YPVDLRVSGKDLVPNHLTYYLFNHCAIWPE---NSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANF 2423
+P +V GKD+ HL Y WP + P+ + +GH L++N KMSKS GN + SEAI K++A+G+R G+ D +F
Sbjct: 147 WPPTCQVIGKDITKFHLYY--------WPAFLMAAGLSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAEGLRYFLLKHGNPSYDCSF 232
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Match: Y105E8A.20 (pep chromosome:WBcel235:I:14486898:14495255:-1 gene:WBGene00013678.1 transcript:Y105E8A.20a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y105E8A.20) HSP 1 Score: 55.4546 bits (132), Expect = 1.766e-7 Identity = 33/94 (35.11%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 2151 YPVDLRVSGKDLVPNHLTYYLFNHCAIWPE---NSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANF 2423
+P +V GKD+ HL Y WP + P+ + +GH L++N KMSKS GN + SEAI K++A+G+R G+ D +F
Sbjct: 147 WPPTCQVIGKDITKFHLYY--------WPAFLMAAGLSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAEGLRYFLLKHGNPSYDCSF 232
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Match: Y105E8A.20 (pep chromosome:WBcel235:I:14486878:14496560:-1 gene:WBGene00013678.1 transcript:Y105E8A.20b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y105E8A.20) HSP 1 Score: 55.4546 bits (132), Expect = 2.066e-7 Identity = 33/94 (35.11%), Postives = 49/94 (52.13%), Query Frame = 3
Query: 2151 YPVDLRVSGKDLVPNHLTYYLFNHCAIWPE---NSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANF 2423
+P +V GKD+ HL Y WP + P+ + +GH L++N KMSKS GN + SEAI K++A+G+R G+ D +F
Sbjct: 265 WPPTCQVIGKDITKFHLYY--------WPAFLMAAGLSLPQKVFIHGHWLIDNVKMSKSLGNVVNPSEAITKFTAEGLRYFLLKHGNPSYDCSF 350
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Fly
Match: LeuRS (gene:FBgn0284253 transcript:FBtr0345640) HSP 1 Score: 1118.99 bits (2893), Expect = 0.000e+0 Identity = 577/1164 (49.57%), Postives = 786/1164 (67.53%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKN--KYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIE--TPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHG-VLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGD-YHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFR-----------XXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLK-TPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSD-EKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAME-SNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIR-DSTAVELYHFIDEKASARLIP 3599
RKGT K+ ++ IE Q+ WE +V E++ K+ K+FVTFP+PYMNG LHLGH FSLSK E+SM Y RLKG+ LW FGFHCTGMPIK+ ADKL RE+E FGFPP FPE E PVA E +E+ +K KGKKSKAVAK+G KYQWQIM+ G+ DEEIK F ++W+ Y+PPL + ++KR+G+ VDWRR+FITTDANP++DSFVRWQF LK+ KIM+GKR TI+SP D QPCMDHDRSSGEGVGPQEYTLIKMK+ + P+ L IK +F+VAATLRPETMYGQTNCW+HP I+Y+A ++ K+ V + RAARNM YQ T GE+ +L++ G++L+G L APLT +K +Y+LPM SIK++KGTG+VTSVPSDSPDDYAAL DL++KE R Y ++D VLP+EP+ +I++P G+ AV E KI+SQND DKL EAKE CY FY G +++G +AG +Q K+ +Q L+ + A Y EPE+ ++SRS ECVVALC+QWYLNY + +W++ L+ + TF +E R NFEA L LHEYACSR+YGLGT++PWD+++L+ESLSDSTIYMA+YTV H+LQGG+ G GI +DMT + W+Y+ + + + L LRREF YWYP+DLRVSGKDL+ NHLT+ L+NH AIWP N + WPK +R NGHLLLN+ KMSKS GNFLT++EA++K+SADGMR+ ADAGDS+EDANFVE ADAG+LRLY+FIEWVKE++E++ ++R G +D VF + +N ++T+ NY++M++K L+ GF+E Q RD+YRE C + H DL+ F+ Q L++SPICPH+ +++W + NK SI++ WP G ++E YL +H FR K K + + + N ++W+AK+YPPWQ +LD++ ++ +K LPDNK + + L + ELKK MK+ M Q IR K E + V+ L T E DE+ V+ SN Y+ TL+LD+ LE+KY+D+ S EK + P P I+F V P V++E +N + R+++ VN I +GD+ ++ +++ I ++ D+ ++++ + D R IP
Sbjct: 6 RKGTFKVEYLQKIEREVQQRWEAERVHESDAPTAPKKRQAEKFFVTFPFPYMNGRLHLGHTFSLSKAEYSMRYHRLKGRRVLWPFGFHCTGMPIKACADKLTRELEQFGFPPQFPETEEVVPVAAEAASEVPKDKSKGKKSKAVAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRRTFITTDANPYFDSFVRWQFNHLKERGKIMYGKRYTIYSPKDGQPCMDHDRSSGEGVGPQEYTLIKMKVLE-VPKALSSIKQPIFMVAATLRPETMYGQTNCWLHPDIKYIAWQANKNNEVWVSTRRAARNMTYQG-FTAVEGEIKVLAEVTGQDLLGVPLSAPLTKHKVVYSLPMLSIKEDKGTGVVTSVPSDSPDDYAALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKIQSQNDKDKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDLQKRLVDANEADVYYEPEKTIMSRSADECVVALCNQWYLNYGEPEWQAQATKILHGMETFHEEARNNFEACLNWLHEYACSRTYGLGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFRGEKP-GPFGIKPSDMTGEIWDYIFFKETPLPKKTAIK-QEHLAVLRREFEYWYPMDLRVSGKDLIQNHLTFCLYNHAAIWP-NDENKWPKGMRVNGHLLLNSAKMSKSDGNFLTLTEAVDKFSADGMRLCLADAGDSVEDANFVESTADAGILRLYTFIEWVKEMLENRSSLRKGTDKTFNDQVFLSELNLKTQQTDENYRKMLFKEALRSGFYELQLARDKYRELCGANGMHEDLVLEFIRRQALLVSPICPHMAEHVWGLLGNK-ESIVHARWPEVGAINEVDILCSEYLMEAAHSFRLNLKNLLQIKGKAGKDKSVNVQAAKPNRGLVWVAKTYPPWQCCVLDTMKELFNKSQALPDNKVIAATLQQKAELKKFMKRVMPFAQMIREKV-ESGKGVAALAVTLEFDERQVLISNLEYLKNTLDLDV--LEIKYTDDPSAPEKTREEVRPGSPFISFSV-------------APNVSVELTNPIERSSLFQVN-----------TVISEGDTVQSLREKLSKIIGLKTDAATLKIWRYEDPVLGPRKIP 1136
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Fly
Match: LeuRS (gene:FBgn0284253 transcript:FBtr0077562) HSP 1 Score: 1118.99 bits (2893), Expect = 0.000e+0 Identity = 577/1164 (49.57%), Postives = 786/1164 (67.53%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKN--KYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIE--TPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHG-VLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGD-YHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFR-----------XXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLK-TPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSD-EKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAME-SNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIR-DSTAVELYHFIDEKASARLIP 3599
RKGT K+ ++ IE Q+ WE +V E++ K+ K+FVTFP+PYMNG LHLGH FSLSK E+SM Y RLKG+ LW FGFHCTGMPIK+ ADKL RE+E FGFPP FPE E PVA E +E+ +K KGKKSKAVAK+G KYQWQIM+ G+ DEEIK F ++W+ Y+PPL + ++KR+G+ VDWRR+FITTDANP++DSFVRWQF LK+ KIM+GKR TI+SP D QPCMDHDRSSGEGVGPQEYTLIKMK+ + P+ L IK +F+VAATLRPETMYGQTNCW+HP I+Y+A ++ K+ V + RAARNM YQ T GE+ +L++ G++L+G L APLT +K +Y+LPM SIK++KGTG+VTSVPSDSPDDYAAL DL++KE R Y ++D VLP+EP+ +I++P G+ AV E KI+SQND DKL EAKE CY FY G +++G +AG +Q K+ +Q L+ + A Y EPE+ ++SRS ECVVALC+QWYLNY + +W++ L+ + TF +E R NFEA L LHEYACSR+YGLGT++PWD+++L+ESLSDSTIYMA+YTV H+LQGG+ G GI +DMT + W+Y+ + + + L LRREF YWYP+DLRVSGKDL+ NHLT+ L+NH AIWP N + WPK +R NGHLLLN+ KMSKS GNFLT++EA++K+SADGMR+ ADAGDS+EDANFVE ADAG+LRLY+FIEWVKE++E++ ++R G +D VF + +N ++T+ NY++M++K L+ GF+E Q RD+YRE C + H DL+ F+ Q L++SPICPH+ +++W + NK SI++ WP G ++E YL +H FR K K + + + N ++W+AK+YPPWQ +LD++ ++ +K LPDNK + + L + ELKK MK+ M Q IR K E + V+ L T E DE+ V+ SN Y+ TL+LD+ LE+KY+D+ S EK + P P I+F V P V++E +N + R+++ VN I +GD+ ++ +++ I ++ D+ ++++ + D R IP
Sbjct: 6 RKGTFKVEYLQKIEREVQQRWEAERVHESDAPTAPKKRQAEKFFVTFPFPYMNGRLHLGHTFSLSKAEYSMRYHRLKGRRVLWPFGFHCTGMPIKACADKLTRELEQFGFPPQFPETEEVVPVAAEAASEVPKDKSKGKKSKAVAKTGAAKYQWQIMQSLGLKDEEIKDFANAEHWLNYFPPLAVQDLKRIGVHVDWRRTFITTDANPYFDSFVRWQFNHLKERGKIMYGKRYTIYSPKDGQPCMDHDRSSGEGVGPQEYTLIKMKVLE-VPKALSSIKQPIFMVAATLRPETMYGQTNCWLHPDIKYIAWQANKNNEVWVSTRRAARNMTYQG-FTAVEGEIKVLAEVTGQDLLGVPLSAPLTKHKVVYSLPMLSIKEDKGTGVVTSVPSDSPDDYAALVDLQKKEAFRQKYGLKDEMVLPYEPIPIIEVPTLGKLSAVHAYETLKIQSQNDKDKLAEAKEMCYLKSFYDGVMLVGAFAGRKIQDVKKDLQKRLVDANEADVYYEPEKTIMSRSADECVVALCNQWYLNYGEPEWQAQATKILHGMETFHEEARNNFEACLNWLHEYACSRTYGLGTKLPWDDKWLIESLSDSTIYMAFYTVVHLLQGGTFRGEKP-GPFGIKPSDMTGEIWDYIFFKETPLPKKTAIK-QEHLAVLRREFEYWYPMDLRVSGKDLIQNHLTFCLYNHAAIWP-NDENKWPKGMRVNGHLLLNSAKMSKSDGNFLTLTEAVDKFSADGMRLCLADAGDSVEDANFVESTADAGILRLYTFIEWVKEMLENRSSLRKGTDKTFNDQVFLSELNLKTQQTDENYRKMLFKEALRSGFYELQLARDKYRELCGANGMHEDLVLEFIRRQALLVSPICPHMAEHVWGLLGNK-ESIVHARWPEVGAINEVDILCSEYLMEAAHSFRLNLKNLLQIKGKAGKDKSVNVQAAKPNRGLVWVAKTYPPWQCCVLDTMKELFNKSQALPDNKVIAATLQQKAELKKFMKRVMPFAQMIREKV-ESGKGVAALAVTLEFDERQVLISNLEYLKNTLDLDV--LEIKYTDDPSAPEKTREEVRPGSPFISFSV-------------APNVSVELTNPIERSSLFQVN-----------TVISEGDTVQSLREKLSKIIGLKTDAATLKIWRYEDPVLGPRKIP 1136
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Zebrafish
Match: lars1b (leucyl-tRNA synthetase 1b [Source:ZFIN;Acc:ZDB-GENE-030114-7]) HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0 Identity = 376/825 (45.58%), Postives = 527/825 (63.88%), Query Frame = 3
Query: 1275 MFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHN--------AAIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
M +IK++KGTG+VTSVPSD+PDD AALRD+K+K+ R Y I+D+ VLPFEPV +I+IP YG A +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E+WK L + TF DE R+NFEA L L E+ACSR+YGLGTR+PW+EQ+L+ESLSDSTIYMAYYTVAH+LQGG L G+ G + GI MT + W+Y+ P+ L LRREF +WYPVD+RVSGKDLVPNHL+YYL+NH A+WP +S + WP+ +RANGHLLLN+EKMSKSTGNFLT+S+AI K+SADGMR+A ADAGD++EDANFVE MADAG+LRL++++EWVKE++ ++ N+RTGP +D VF + +N I +T+ +Y++MMYK L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++ W+ +L K S++M WP G VDE L +YL +H+ R + + ++ + I++AK+YPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L LD ++++ ++ E +DEK+ + CCP +P F +S P + +++VNP +G S +I+I GDS ++ RR++ I+D + V+L + D R IP+ + P+ ++ F +S +S + S NG+ IG+
Sbjct: 1 MLTIKEDKGTGVVTSVPSDAPDDIAALRDIKKKQALREKYGIQDFMVLPFEPVPIIEIPGYGNLSAPLVCDELKIQSQNDREKLAEAKEKVYLKGFYEGIMLVEGFKGQKVQDVKKPIQKMMVEKGEALIYMEPEKQVLSRSADECVVALCDQWYLDYGNEEWKKQAHGVLEHLETFCDETRKNFEATLAWLQEHACSRTYGLGTRLPWNEQWLIESLSDSTIYMAYYTVAHLLQGGVLSGQ-GPSPLGIRPQQMTREVWDYIFFKTSPFPKTDIPK--EHLLKLRREFEFWYPVDVRVSGKDLVPNHLSYYLYNHVAMWPNDSGK-WPQAVRANGHLLLNSEKMSKSTGNFLTLSQAIAKFSADGMRLALADAGDTVEDANFVEAMADAGILRLFTWVEWVKEMIANQDNLRTGPADTFNDRVFISEMNSGIIKTDQHYERMMYKEALKSGFFEFQAAKDKYRELAIEGMHKDLVFQFIENQTLLLAPICPHLCEHTWS-LLGKSSTVMKAQWPTAGPVDEILIRSSQYLMDTAHDLRLRLKAYTQPAKGKKGDNKPPAKPTHCTIYVAKTYPPWQHSALSLLGKHYKSNNGALPDNKVIAMELGAMPELKKYMKRVMPFVAMIKDNLEKNGPRVLDLEL-EFDERAVLLENIVYLTNSLELD--QIDVVFASE-ADEKVKEDCCPGKPFCVF-------RSEPGVI----------------ISLVNPQPSNGLFSTKIDIRQGDSKDSIIRRLSRVNRGIKDLSKVKLMRYEDPVLGPRRIPVLGKEEEGKLPVSNSSVFHISLQESKVHMSDNGLKVDIGD 793
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Zebrafish
Match: lars1b (leucyl-tRNA synthetase 1b [Source:ZFIN;Acc:ZDB-GENE-030114-7]) HSP 1 Score: 645.966 bits (1665), Expect = 0.000e+0 Identity = 342/773 (44.24%), Postives = 483/773 (62.48%), Query Frame = 3
Query: 1431 VEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHN--------AAIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
V +I+IP YG A +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E+WK L + TF DE R+NFEA L L E+ACSR+YGLGTR+PW+EQ+L+ESLSDSTIYMAYYTVAH+LQGG L G+ G + GI MT + W+Y+ P+ L LRREF +WYPVD+RVSGKDLVPNHL+YYL+NH A+WP +S + WP+ +RANGHLLLN+EKMSKSTGNFLT+S+AI K+SADGMR+A ADAGD++EDANFVE MADAG+LRL++++EWVKE++ ++ N+RTGP +D VF + +N I +T+ +Y++MMYK L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++ W+ +L K S++M WP G VDE L +YL +H+ R + + ++ + I++AK+YPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L LD ++++ ++ E +DEK+ + CCP +P F +S P + +++VNP +G S +I+I GDS ++ RR++ I+D + V+L + D R IP+ + P+ ++ F +S +S + S NG+ IG+
Sbjct: 2 VPIIEIPGYGNLSAPLVCDELKIQSQNDREKLAEAKEKVYLKGFYEGIMLVEGFKGQKVQDVKKPIQKMMVEKGEALIYMEPEKQVLSRSADECVVALCDQWYLDYGNEEWKKQAHGVLEHLETFCDETRKNFEATLAWLQEHACSRTYGLGTRLPWNEQWLIESLSDSTIYMAYYTVAHLLQGGVLSGQ-GPSPLGIRPQQMTREVWDYIFFKTSPFPKTDIPK--EHLLKLRREFEFWYPVDVRVSGKDLVPNHLSYYLYNHVAMWPNDSGK-WPQAVRANGHLLLNSEKMSKSTGNFLTLSQAIAKFSADGMRLALADAGDTVEDANFVEAMADAGILRLFTWVEWVKEMIANQDNLRTGPADTFNDRVFISEMNSGIIKTDQHYERMMYKEALKSGFFEFQAAKDKYRELAIEGMHKDLVFQFIENQTLLLAPICPHLCEHTWS-LLGKSSTVMKAQWPTAGPVDEILIRSSQYLMDTAHDLRLRLKAYTQPAKGKKGDNKPPAKPTHCTIYVAKTYPPWQHSALSLLGKHYKSNNGALPDNKVIAMELGAMPELKKYMKRVMPFVAMIKDNLEKNGPRVLDLEL-EFDERAVLLENIVYLTNSLELD--QIDVVFASE-ADEKVKEDCCPGKPFCVF-------RSEPGVI----------------ISLVNPQPSNGLFSTKIDIRQGDSKDSIIRRLSRVNRGIKDLSKVKLMRYEDPVLGPRRIPVLGKEEEGKLPVSNSSVFHISLQESKVHMSDNGLKVDIGD 742
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Zebrafish
Match: lars1a (leucyl-tRNA synthetase 1a [Source:ZFIN;Acc:ZDB-GENE-110411-16]) HSP 1 Score: 408.297 bits (1048), Expect = 1.455e-131 Identity = 213/354 (60.17%), Postives = 266/354 (75.14%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFE--ANPIYGKD-KKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTE---INLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDD-VFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGK 1211
RKGTAKL+ +K IE Q++WE +K+FE A G++ KNKYF+TFPYPYMNG LHLGH F LSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKREME +G+PP FPE + ++KT I +K KGKKSKAVAKSG K+QW IM+ G+ D EI KF E ++W+ Y+PPL + ++KR+G+KVDWRRSFITTD NPFYDSFVRWQF+ LK+ KI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +PYP L +K VFLVAATLRPETM+GQTNCWI P ++YV ++ + I +R+ARNM+YQ T + G V ++ +G+
Sbjct: 4 RKGTAKLDFLKKIEEEVQQKWEQDKLFENEAPATIGENTNKNKYFITFPYPYMNGRLHLGHTFCLSKCEFAVGYQRLKGKQCLFPFGLHCTGMPIKACADKLKREMELYGYPPQFPEEDEEEEEQKKTSDDVIIKDKTKGKKSKAVAKSGSSKFQWDIMKSLGLQDAEIVKFAEAEHWLDYFPPLAVEDLKRMGLKVDWRRSFITTDVNPFYDSFVRWQFINLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKVVEPYPTKLGALKGKTVFLVAATLRPETMFGQTNCWIRPDMKYVVFETANGDLFISTQRSARNMSYQG-FTKENGVVPVIMNIMGQ 356
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Match: lars (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:548548]) HSP 1 Score: 1154.04 bits (2984), Expect = 0.000e+0 Identity = 607/1202 (50.50%), Postives = 815/1202 (67.80%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPV----AIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVA-GNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDMSDKE-GKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ K+FE N + ++ K KY VTFPYPYMNG LHLGH FSLSKCEF++GY+R+KGK L+ FG HCTGMPIK+ ADKLKRE E FG+PP FPE E A +E I +K KGKKSKA AKSG KYQW IM+ G++DEEI +F+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NPFYDSFV+WQFL LK+ N+I FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +P P L +K +VFLVAATLRPETM+GQTNCW+ P + Y+A ++ + IC +RAARNM+YQ D G V ++ + +G++L+G AL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRDLK+K+ R Y I+D VLPFEPV +IDIP YG A +E KI+SQND +KL EAKEK Y GFY G +I+ Y G VQ K+ IQ +I G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y + WK+ T CL + TF +E RRNFEA+L L E+ACSR+YGLG+R+PWDEQ+L+ESLSDSTIYMAYYTV H+LQG L G+ G + GI MT + W+Y+ + E KL+ L++EF +WYPVDLRVSGKDLVPNHL+Y+L+NH A+WPE+S + WP +RANGHLLLN+EKMSKSTGNFLT+SEA+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ + ++R+G +D VFA+ IN I +TE NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++IW+ +L K S+M SWP+ G VDE L +YL +H+ R + ++ + I++AK+YPPWQ L +L + G+LPDNK + + L+ PELKK MK+ M + I+ ++ V L+ E DE++V+ N Y+ +L LD ++E+K++ + +D+K+ + CCP +P F V + + P V V +VNP +G S +I I +GDS ++ RR+ D+ I+D T V+L + D R +P+ + I A F + ++ + + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKDIQEKWDAQKLFEVNASDLQAQNSKGKYLVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRMKGKICLFPFGLHCTGMPIKACADKLKRETELFGYPPQFPEEEEEEEETSAKKEDEVIIKDKAKGKKSKAAAKSGSSKYQWGIMKSLGLSDEEIIRFSEAEHWLDYFPPLAVEDLKSMGLKVDWRRSFITTDVNPFYDSFVKWQFLTLKERNRIKFGKRYTIYSPRDGQPCMDHDRQTGEGVGPQEYTLIKMKVLEPIPTKLSGLKGRNVFLVAATLRPETMFGQTNCWLRPDMPYIAFETANGDIFICTQRAARNMSYQGFTKDN-GVVPVVKELMGEDLLGAALSAPLTSYKVIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDLKKKQALRQKYGIKDEMVLPFEPVPIIDIPGYGNLSAPMVCDELKIQSQNDREKLTEAKEKVYLKGFYEGVMIVPGYEGQKVQDVKKPIQKLMIEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGEANWKTQTTECLKSLETFCEETRRNFEASLGWLQEHACSRTYGLGSRLPWDEQWLIESLSDSTIYMAYYTVCHLLQGKELSGQ-GASPLGIRPEQMTKEVWDYIFFKKAPFPKTTIQKE---KLEKLKQEFEFWYPVDLRVSGKDLVPNHLSYFLYNHVAMWPEDSGK-WPVAVRANGHLLLNSEKMSKSTGNFLTLSEAVEKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLANFDSLRSGTSHTFNDRVFASEINAGIVKTEQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFKFIETQTLLLAPICPHLCEHIWS-LLGKTDSLMKASWPVTGPVDEVLIRSSQYLTETAHDLRLRLKNYMAPAKGKKVDKQPPQKPSHCTIYVAKNYPPWQHKTLLTLRKHYEANAGQLPDNKVIATELNALPELKKYMKRVMPFVAMIKENLEKKGLRVLDLEL-EFDEQTVLLENIVYLTNSLELD--QIEVKFASD-ADDKVKEDCCPGKP---FSVFRTE-----PGV---------------PVFLVNPQPANGHFSTKIAIREGDSRESIIRRLMKTDR-GIKDVTKVKLMRYDDPVLGPRRVPVLGKEEVGKSVISPKAAFHIDLNEKKVHIADNGLKTDIGD 1170
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Match: lars (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:548548]) HSP 1 Score: 1129.78 bits (2921), Expect = 0.000e+0 Identity = 574/1069 (53.70%), Postives = 757/1069 (70.81%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPV----AIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDMSDKE-GKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITF 3329
RKGTAK++ +K IE Q++W+ K+FE N + K KY VTFPYPYMNG LHLGH FSLSKCEF++GY+R+KGK L+ FG HCTGMPIK+ ADKLKRE E FG+PP FPE E A +E I +K KGKKSKA AKSG KYQW IM+ G++DEEI +F+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NPFYDSFV+WQFL LK+ N+I FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +P P L +K +VFLVAATLRPETM+GQTNCW+ P + Y+A ++ + IC +RAARNM+YQ D G V ++ + +G++L+G AL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRDLK+K+ R Y I+D VLPFEPV +IDIP YG A +E KI+SQND +KL EAKEK Y GFY G +I+ Y G VQ K+ IQ +I G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y + WK+ T CL + TF +E RRNFEA+L L E+ACSR+YGLG+R+PWDEQ+L+ESLSDSTIYMAYYTV H+LQG L G+ G + GI MT + W+Y+ + KL+ L++EF +WYPVDLRVSGKDLVPNHL+Y+L+NH A+WPE+S + WP +RANGHLLLN+EKMSKSTGNFLT+SEA+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ + ++R+G +D VFA+ IN I +TE NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++IW+ +L K S+M SWP+ G VDE L +YL +H+ R + ++ + I++AK+YPPWQ L +L + G+LPDNK + + L+ PELKK MK+ M + I+ ++ V L+ E DE++V+ N Y+ +L LD ++E+K++ + +D+K+ + CCP +P F
Sbjct: 4 RKGTAKVDFLKKIEKDIQEKWDAQKLFEVNASDLQHKTSICKYLVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRMKGKICLFPFGLHCTGMPIKACADKLKRETELFGYPPQFPEEEEEEEETSAKKEDEVIIKDKAKGKKSKAAAKSGSSKYQWGIMKSLGLSDEEIIRFSEAEHWLDYFPPLAVEDLKSMGLKVDWRRSFITTDVNPFYDSFVKWQFLTLKERNRIKFGKRYTIYSPRDGQPCMDHDRQTGEGVGPQEYTLIKMKVLEPIPTKLSGLKGRNVFLVAATLRPETMFGQTNCWLRPDMPYIAFETANGDIFICTQRAARNMSYQGFTKDN-GVVPVVKELMGEDLLGAALSAPLTSYKVIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDLKKKQALRQKYGIKDEMVLPFEPVPIIDIPGYGNLSAPMVCDELKIQSQNDREKLTEAKEKVYLKGFYEGVMIVPGYEGQKVQDVKKPIQKLMIEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGEANWKTQTTECLKSLETFCEETRRNFEASLGWLQEHACSRTYGLGSRLPWDEQWLIESLSDSTIYMAYYTVCHLLQGKELSGQ-GASPLGIRPEQMTKEVWDYIFFKKAPFPKTTIQK--EKLEKLKQEFEFWYPVDLRVSGKDLVPNHLSYFLYNHVAMWPEDSGK-WPVAVRANGHLLLNSEKMSKSTGNFLTLSEAVEKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLANFDSLRSGTSHTFNDRVFASEINAGIVKTEQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFKFIETQTLLLAPICPHLCEHIWS-LLGKTDSLMKASWPVTGPVDEVLIRSSQYLTETAHDLRLRLKNYMAPAKGKKVDKQPPQKPSHCTIYVAKNYPPWQHKTLLTLRKHYEANAGQLPDNKVIATELNALPELKKYMKRVMPFVAMIKENLEKKGLRVLDLEL-EFDEQTVLLENIVYLTNSLELD--QIEVKFASD-ADDKVKEDCCPGKPFSVF 1062
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Match: lars (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:548548]) HSP 1 Score: 1104.35 bits (2855), Expect = 0.000e+0 Identity = 592/1199 (49.37%), Postives = 795/1199 (66.31%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPV----AIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDMSDKE-GKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ K+FE N D K KY VTFPYPYMNG LHLGH FSLSKCE S L+ H +++ ADKLKRE E FG+PP FPE E A +E I +K KGKKSKA AKSG KYQW IM+ G++DEEI +F+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NPFYDSFV+WQFL LK+ N+I FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +P P L +K +VFLVAATLRPETM+GQTNCW+ P + Y+A ++ + IC +RAARNM+YQ D G V ++ + +G++L+G AL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRDLK+K+ R Y I+D VLPFEPV +IDIP YG A +E KI+SQND +KL EAKEK Y GFY G +I+ Y G VQ K+ IQ +I G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y + WK+ T CL + TF +E RRNFEA+L L E+ACSR+YGLG+R+PWDEQ+L+ESLSDSTIYMAYYTV H+LQG L G+ G + GI MT + W+Y+ + KL+ L++EF +WYPVDLRVSGKDLVPNHL+Y+L+NH A+WPE+S + WP +RANGHLLLN+EKMSKSTGNFLT+SEA+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ + ++R+G +D VFA+ IN I +TE NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++IW+ +L K S+M SWP+ G VDE L +YL +H+ R + ++ + I++AK+YPPWQ L +L + G+LPDNK + + L+ PELKK MK+ M + I+ ++ V L+ E DE++V+ N Y+ +L LD ++E+K++ + +D+K+ + CCP +P F V + + P V V +VNP +G S +I I +GDS ++ RR+ D+ I+D T V+L + D R +P+ + I A F + ++ + + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKDIQEKWDAQKLFEVN---ASDFKGKYLVTFPYPYMNGRLHLGHTFSLSKCEVSACISTLRKSYVTNPVTTH-----LQACADKLKRETELFGYPPQFPEEEEEEEETSAKKEDEVIIKDKAKGKKSKAAAKSGSSKYQWGIMKSLGLSDEEIIRFSEAEHWLDYFPPLAVEDLKSMGLKVDWRRSFITTDVNPFYDSFVKWQFLTLKERNRIKFGKRYTIYSPRDGQPCMDHDRQTGEGVGPQEYTLIKMKVLEPIPTKLSGLKGRNVFLVAATLRPETMFGQTNCWLRPDMPYIAFETANGDIFICTQRAARNMSYQGFTKDN-GVVPVVKELMGEDLLGAALSAPLTSYKVIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDLKKKQALRQKYGIKDEMVLPFEPVPIIDIPGYGNLSAPMVCDELKIQSQNDREKLTEAKEKVYLKGFYEGVMIVPGYEGQKVQDVKKPIQKLMIEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGEANWKTQTTECLKSLETFCEETRRNFEASLGWLQEHACSRTYGLGSRLPWDEQWLIESLSDSTIYMAYYTVCHLLQGKELSGQ-GASPLGIRPEQMTKEVWDYIFFKKAPFPKTTIQK--EKLEKLKQEFEFWYPVDLRVSGKDLVPNHLSYFLYNHVAMWPEDSGK-WPVAVRANGHLLLNSEKMSKSTGNFLTLSEAVEKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLANFDSLRSGTSHTFNDRVFASEINAGIVKTEQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFKFIETQTLLLAPICPHLCEHIWS-LLGKTDSLMKASWPVTGPVDEVLIRSSQYLTETAHDLRLRLKNYMAPAKGKKVDKQPPQKPSHCTIYVAKNYPPWQHKTLLTLRKHYEANAGQLPDNKVIATELNALPELKKYMKRVMPFVAMIKENLEKKGLRVLDLEL-EFDEQTVLLENIVYLTNSLELD--QIEVKFASD-ADDKVKEDCCPGKP---FSVFRTE-----PGV---------------PVFLVNPQPANGHFSTKIAIREGDSRESIIRRLMKTDR-GIKDVTKVKLMRYDDPVLGPRRVPVLGKEEVGKSVISPKAAFHIDLNEKKVHIADNGLKTDIGD 1160
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Match: lars (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:548548]) HSP 1 Score: 1097.03 bits (2836), Expect = 0.000e+0 Identity = 588/1201 (48.96%), Postives = 794/1201 (66.11%), Query Frame = 3
Query: 168 NRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPV----AIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVA-GNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDMSDKE-GKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ K+FE N D +Y FS KC F++GY+R+KGK L+ FG HCTGMPIK+ ADKLKRE E FG+PP FPE E A +E I +K KGKKSKA AKSG KYQW IM+ G++DEEI +F+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NPFYDSFV+WQFL LK+ N+I FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +P P L +K +VFLVAATLRPETM+GQTNCW+ P + Y+A ++ + IC +RAARNM+YQ D G V ++ + +G++L+G AL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRDLK+K+ R Y I+D VLPFEPV +IDIP YG A +E KI+SQND +KL EAKEK Y GFY G +I+ Y G VQ K+ IQ +I G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y + WK+ T CL + TF +E RRNFEA+L L E+ACSR+YGLG+R+PWDEQ+L+ESLSDSTIYMAYYTV H+LQG L G+ G + GI MT + W+Y+ + E KL+ L++EF +WYPVDLRVSGKDLVPNHL+Y+L+NH A+WPE+S + WP +RANGHLLLN+EKMSKSTGNFLT+SEA+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ + ++R+G +D VFA+ IN I +TE NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++IW+ +L K S+M SWP+ G VDE L +YL +H+ R + ++ + I++AK+YPPWQ L +L + G+LPDNK + + L+ PELKK MK+ M + I+ ++ V L+ E DE++V+ N Y+ +L LD ++E+K++ + +D+K+ + CCP +P F V + + P V V +VNP +G S +I I +GDS ++ RR+ D+ I+D T V+L + D R +P+ + I A F + ++ + + NG+ IG+
Sbjct: 3 GRKGTAKVDFLKKIEKDIQEKWDAQKLFEVN---ASDLFERY----------------KTFSKGKCIFAVGYQRMKGKICLFPFGLHCTGMPIKACADKLKRETELFGYPPQFPEEEEEEEETSAKKEDEVIIKDKAKGKKSKAAAKSGSSKYQWGIMKSLGLSDEEIIRFSEAEHWLDYFPPLAVEDLKSMGLKVDWRRSFITTDVNPFYDSFVKWQFLTLKERNRIKFGKRYTIYSPRDGQPCMDHDRQTGEGVGPQEYTLIKMKVLEPIPTKLSGLKGRNVFLVAATLRPETMFGQTNCWLRPDMPYIAFETANGDIFICTQRAARNMSYQGFTKDN-GVVPVVKELMGEDLLGAALSAPLTSYKVIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDLKKKQALRQKYGIKDEMVLPFEPVPIIDIPGYGNLSAPMVCDELKIQSQNDREKLTEAKEKVYLKGFYEGVMIVPGYEGQKVQDVKKPIQKLMIEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGEANWKTQTTECLKSLETFCEETRRNFEASLGWLQEHACSRTYGLGSRLPWDEQWLIESLSDSTIYMAYYTVCHLLQGKELSGQ-GASPLGIRPEQMTKEVWDYIFFKKAPFPKTTIQKE---KLEKLKQEFEFWYPVDLRVSGKDLVPNHLSYFLYNHVAMWPEDSGK-WPVAVRANGHLLLNSEKMSKSTGNFLTLSEAVEKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLANFDSLRSGTSHTFNDRVFASEINAGIVKTEQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFKFIETQTLLLAPICPHLCEHIWS-LLGKTDSLMKASWPVTGPVDEVLIRSSQYLTETAHDLRLRLKNYMAPAKGKKVDKQPPQKPSHCTIYVAKNYPPWQHKTLLTLRKHYEANAGQLPDNKVIATELNALPELKKYMKRVMPFVAMIKENLEKKGLRVLDLEL-EFDEQTVLLENIVYLTNSLELD--QIEVKFASD-ADDKVKEDCCPGKP---FSVFRTE-----PGV---------------PVFLVNPQPANGHFSTKIAIREGDSRESIIRRLMKTDR-GIKDVTKVKLMRYDDPVLGPRRVPVLGKEEVGKSVISPKAAFHIDLNEKKVHIADNGLKTDIGD 1149
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Match: lars (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:548548]) HSP 1 Score: 1077.39 bits (2785), Expect = 0.000e+0 Identity = 577/1164 (49.57%), Postives = 775/1164 (66.58%), Query Frame = 3
Query: 282 KNKYFVTFPYPYMNGNLHLGHAFSLSKCEFS--MGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPV----AIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKD-DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDMSDKE-GKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
K KY VTFPYPYMNG LHLGH FSLSKCE S + +RL+ H +++ ADKLKRE E FG+PP FPE E A +E I +K KGKKSKA AKSG KYQW IM+ G++DEEI +F+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NPFYDSFV+WQFL LK+ N+I FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +P P L +K +VFLVAATLRPETM+GQTNCW+ P + Y+A ++ + IC +RAARNM+YQ D G V ++ + +G++L+G AL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRDLK+K+ R Y I+D VLPFEPV +IDIP YG A +E KI+SQND +KL EAKEK Y GFY G +I+ Y G VQ K+ IQ +I G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y + WK+ T CL + TF +E RRNFEA+L L E+ACSR+YGLG+R+PWDEQ+L+ESLSDSTIYMAYYTV H+LQG L G+ G + GI MT + W+Y+ + KL+ L++EF +WYPVDLRVSGKDLVPNHL+Y+L+NH A+WPE+S + WP +RANGHLLLN+EKMSKSTGNFLT+SEA+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ + ++R+G +D VFA+ IN I +TE NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ ++IW+ +L K S+M SWP+ G VDE L +YL +H+ R + ++ + I++AK+YPPWQ L +L + G+LPDNK + + L+ PELKK MK+ M + I+ ++ V L+ E DE++V+ N Y+ +L LD ++E+K++ + +D+K+ + CCP +P F V + + P V V +VNP +G S +I I +GDS ++ RR+ D+ I+D T V+L + D R +P+ + I A F + ++ + + NG+ IG+
Sbjct: 15 KGKYLVTFPYPYMNGRLHLGHTFSLSKCEVSACISTKRLRKSYVTNPVTTH-----LQACADKLKRETELFGYPPQFPEEEEEEEETSAKKEDEVIIKDKAKGKKSKAAAKSGSSKYQWGIMKSLGLSDEEIIRFSEAEHWLDYFPPLAVEDLKSMGLKVDWRRSFITTDVNPFYDSFVKWQFLTLKERNRIKFGKRYTIYSPRDGQPCMDHDRQTGEGVGPQEYTLIKMKVLEPIPTKLSGLKGRNVFLVAATLRPETMFGQTNCWLRPDMPYIAFETANGDIFICTQRAARNMSYQGFTKDN-GVVPVVKELMGEDLLGAALSAPLTSYKVIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDLKKKQALRQKYGIKDEMVLPFEPVPIIDIPGYGNLSAPMVCDELKIQSQNDREKLTEAKEKVYLKGFYEGVMIVPGYEGQKVQDVKKPIQKLMIEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGEANWKTQTTECLKSLETFCEETRRNFEASLGWLQEHACSRTYGLGSRLPWDEQWLIESLSDSTIYMAYYTVCHLLQGKELSGQ-GASPLGIRPEQMTKEVWDYIFFKKAPFPKTTIQK--EKLEKLKQEFEFWYPVDLRVSGKDLVPNHLSYFLYNHVAMWPEDSGK-WPVAVRANGHLLLNSEKMSKSTGNFLTLSEAVEKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLANFDSLRSGTSHTFNDRVFASEINAGIVKTEQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFKFIETQTLLLAPICPHLCEHIWS-LLGKTDSLMKASWPVTGPVDEVLIRSSQYLTETAHDLRLRLKNYMAPAKGKKVDKQPPQKPSHCTIYVAKNYPPWQHKTLLTLRKHYEANAGQLPDNKVIATELNALPELKKYMKRVMPFVAMIKENLEKKGLRVLDLEL-EFDEQTVLLENIVYLTNSLELD--QIEVKFASD-ADDKVKEDCCPGKP---FSVFRTE-----PGV---------------PVFLVNPQPANGHFSTKIAIREGDSRESIIRRLMKTDR-GIKDVTKVKLMRYDDPVLGPRRVPVLGKEEVGKSVISPKAAFHIDLNEKKVHIADNGLKTDIGD 1139
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Match: Lars (leucyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1913808]) HSP 1 Score: 1168.68 bits (3022), Expect = 0.000e+0 Identity = 602/1203 (50.04%), Postives = 815/1203 (67.75%), Query Frame = 3
Query: 168 NRKGTAKLNTIKDIEVAKQKEWENNKVFEANPI----YGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINL---NXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLID-MSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAK++ +K+IE Q++WE KVFE + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK+ L+ FG HCTGMPIK+ ADKLKRE+E +G PP FPE E ++ +K KGKKSKA AK+G KYQW IM+ G++D++I KF+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC +RAARNM+YQ T G V ++ + +G+E++G +L APLT YK +Y LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ + I D VLPFEPV V++IP G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G +Q K+ IQ ++I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y DE WK T CL + TF +E R+NFEA+L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG L+G++ + GI MT D W+YV D P+ KLD L++EF +WYPVDLR SGKDL+PNHL+YY++NH A+WPE SD+ WP ++RANGHLLLN+EKMSKSTGNFLT+S+A++K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ S ++R+GP +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE H +L+ F+E+Q ++L+P CPH+ ++IWT +L KP SIM+ SWP+ G VDE L +YL ++H+ R + ++ + I++AK+YP WQ L +L GKLPDNK + S L PELKK MKK M + I+ ++ V L+ E DE++V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F P V V++VNP SG S +I+I GDS ++ RR+ D+ I+D + V+L F D R +P+ + I NA F V + + NG+ IG+
Sbjct: 3 GRKGTAKVDFLKEIEKEAQQKWEAEKVFEVSASRLEKQKQSSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPEEEEEEEESSAKPGDIVVRDKAKGKKSKAAAKAGSSKYQWDIMKSLGLSDDDIVKFSEAEHWLDYFPPLAVQDLKTIGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLVKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETANGDIFICTQRAARNMSYQG-FTKHNGVVPVVKELMGEEILGASLSAPLTCYKVVYVLPMLTIKEDKGTGVVTSVPSDSPDDLAALRDLKKKQALRTKFGIRDDMVLPFEPVPVLEIPGIGNLPAVTVCDELKIQSQNDREKLAEAKEKLYLRGFYDGVMLVDGFKGQKIQHVKKTIQKNMIDAGDALIYMEPEKQVMSRSADECVVALCDQWYLDYGDENWKKQTFQCLKNMETFCEESRKNFEASLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGDLNGQAE-SPLGIRPQQMTKDVWDYVFFKDAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRASGKDLIPNHLSYYIYNHVAMWPEQSDK-WPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLASCSSLRSGPADSFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELATEGMHRELVFRFIEVQTILLTPFCPHLCEHIWT-LLGKPDSIMHASWPVAGPVDESLIRSSQYLMEVAHDLRLRLKNYMMPAKGKKTDKQPAQRPSHCTIYVAKNYPVWQHITLTTLRSHFEANNGKLPDNKVIASELGSLPELKKYMKKVMPFVAMIKENMEKKGPRVLDLEL-EFDEQAVLMENIVYLTNSLELE--HIEVKFASEAED-KVREECCPGKPLNVF--------RTEPGV---------------PVSLVNPQPSSGHFSTKIDIRQGDSCESIIRRLMKTDR-GIKDLSKVKLMRFDDPLLGPRRVPVLGREHSEKTLISENAVFHVDLVSKKVHLTENGLRTDIGD 1171
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Match: Lars (leucyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1913808]) HSP 1 Score: 236.884 bits (603), Expect = 8.101e-71 Identity = 109/178 (61.24%), Postives = 141/178 (79.21%), Query Frame = 3
Query: 2019 GITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFA 2552
GI MT D W+YV D P+ KLD L++EF +WYPVDLR SGKDL+PNHL+YY++NH A+WPE SD+ WP ++RANGHLLLN+EKMSKSTGNFLT+S+A++K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ S ++R+GP +D VFA
Sbjct: 9 GIRPQQMTKDVWDYVFFKDAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRASGKDLIPNHLSYYIYNHVAMWPEQSDK-WPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLASCSSLRSGPADSFNDRVFA 183
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Match: Lars (leucyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1913808]) HSP 1 Score: 130.183 bits (326), Expect = 4.871e-35 Identity = 61/98 (62.24%), Postives = 74/98 (75.51%), Query Frame = 3
Query: 168 NRKGTAKLNTIKDIEVAKQKEWENNKVFEANPI----YGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIK 449
RKGTAK++ +K+IE Q++WE KVFE + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK+ L+ FG HCTGMPIK
Sbjct: 3 GRKGTAKVDFLKEIEKEAQQKWEAEKVFEVSASRLEKQKQSSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIK 100
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Match: Lars (leucyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1913808]) HSP 1 Score: 63.1586 bits (152), Expect = 1.572e-11 Identity = 44/99 (44.44%), Postives = 66/99 (66.67%), Query Frame = 3
Query: 444 IKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINL---NXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRL 731
+ + ADKLKRE+E +G PP FPE E ++ +K KGKKSKA AK+G KYQW IM+ G++D++I KF+E ++W+ Y+PPL + ++K +
Sbjct: 1 MAACADKLKREIELYGCPPDFPEEEEEEEESSAKPGDIVVRDKAKGKKSKAAAKAGSSKYQWDIMKSLGLSDDDIVKFSEAEHWLDYFPPLAVQDLKTI 99
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Match: Lars (leucyl-tRNA synthetase [Source:MGI Symbol;Acc:MGI:1913808]) HSP 1 Score: 50.8322 bits (120), Expect = 9.494e-8 Identity = 17/41 (41.46%), Postives = 29/41 (70.73%), Query Frame = 3
Query: 2652 RDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWT 2774
+D+YRE H +L+ F+E+Q ++L+P CPH+ ++IWT
Sbjct: 4 KDKYRELATEGMHRELVFRFIEVQTILLTPFCPHLCEHIWT 44
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Match: sp|Q9P2J5|SYLC_HUMAN (Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2) HSP 1 Score: 1184.09 bits (3062), Expect = 0.000e+0 Identity = 609/1199 (50.79%), Postives = 820/1199 (68.39%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETP---VAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ +VFE N + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E +++ + I +K KGKKSKA AK+G KYQW IM+ G++DEEI KF+E ++W+ Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC ++AARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ Y I D VLPFEPV VI+IP +G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ +I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E WK T CL + TF +E RRNFEA L L E+ACSR+YGLGT +PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG+L G++ + GI MT + W+YV + + KLD L++EF +WYPVDLRVSGKDLVPNHL+YYL+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP S +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G V+E L +YL ++H+ R + ++ + I++AK+YPPWQ + L L GKLPDNK + S L PELKK MKK M + I+ + + L+ E DEK+V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F + P V +V++VNP +G S +IEI GD+ ++ RR+ I+D + V+L F D R +P+ + + PI +A F+V I + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAE-SPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAK--EKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVNEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQL-EFDEKAVLMENIVYLTNSLELE--HIEVKFASEAED-KIREDCCPGKPLNVFRI--------EPGV---------------SVSLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Match: sp|Q8BMJ2|SYLC_MOUSE (Leucine--tRNA ligase, cytoplasmic OS=Mus musculus OX=10090 GN=Lars1 PE=1 SV=2) HSP 1 Score: 1168.68 bits (3022), Expect = 0.000e+0 Identity = 602/1203 (50.04%), Postives = 815/1203 (67.75%), Query Frame = 3
Query: 168 NRKGTAKLNTIKDIEVAKQKEWENNKVFEANPI----YGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINL---NXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLID-MSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAK++ +K+IE Q++WE KVFE + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK+ L+ FG HCTGMPIK+ ADKLKRE+E +G PP FPE E ++ +K KGKKSKA AK+G KYQW IM+ G++D++I KF+E ++W+ Y+PPL + ++K +G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC +RAARNM+YQ T G V ++ + +G+E++G +L APLT YK +Y LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ + I D VLPFEPV V++IP G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G +Q K+ IQ ++I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y DE WK T CL + TF +E R+NFEA+L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG L+G++ + GI MT D W+YV D P+ KLD L++EF +WYPVDLR SGKDL+PNHL+YY++NH A+WPE SD+ WP ++RANGHLLLN+EKMSKSTGNFLT+S+A++K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ S ++R+GP +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE H +L+ F+E+Q ++L+P CPH+ ++IWT +L KP SIM+ SWP+ G VDE L +YL ++H+ R + ++ + I++AK+YP WQ L +L GKLPDNK + S L PELKK MKK M + I+ ++ V L+ E DE++V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F P V V++VNP SG S +I+I GDS ++ RR+ D+ I+D + V+L F D R +P+ + I NA F V + + NG+ IG+
Sbjct: 3 GRKGTAKVDFLKEIEKEAQQKWEAEKVFEVSASRLEKQKQSSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPEEEEEEEESSAKPGDIVVRDKAKGKKSKAAAKAGSSKYQWDIMKSLGLSDDDIVKFSEAEHWLDYFPPLAVQDLKTIGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLVKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETANGDIFICTQRAARNMSYQG-FTKHNGVVPVVKELMGEEILGASLSAPLTCYKVVYVLPMLTIKEDKGTGVVTSVPSDSPDDLAALRDLKKKQALRTKFGIRDDMVLPFEPVPVLEIPGIGNLPAVTVCDELKIQSQNDREKLAEAKEKLYLRGFYDGVMLVDGFKGQKIQHVKKTIQKNMIDAGDALIYMEPEKQVMSRSADECVVALCDQWYLDYGDENWKKQTFQCLKNMETFCEESRKNFEASLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGDLNGQAE-SPLGIRPQQMTKDVWDYVFFKDAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRASGKDLIPNHLSYYIYNHVAMWPEQSDK-WPVSVRANGHLLLNSEKMSKSTGNFLTLSQAVDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMLASCSSLRSGPADSFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELATEGMHRELVFRFIEVQTILLTPFCPHLCEHIWT-LLGKPDSIMHASWPVAGPVDESLIRSSQYLMEVAHDLRLRLKNYMMPAKGKKTDKQPAQRPSHCTIYVAKNYPVWQHITLTTLRSHFEANNGKLPDNKVIASELGSLPELKKYMKKVMPFVAMIKENMEKKGPRVLDLEL-EFDEQAVLMENIVYLTNSLELE--HIEVKFASEAED-KVREECCPGKPLNVF--------RTEPGV---------------PVSLVNPQPSSGHFSTKIDIRQGDSCESIIRRLMKTDR-GIKDLSKVKLMRFDDPLLGPRRVPVLGREHSEKTLISENAVFHVDLVSKKVHLTENGLRTDIGD 1171
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Match: sp|Q5R614|SYLC_PONAB (Leucine--tRNA ligase, cytoplasmic OS=Pongo abelii OX=9601 GN=LARS1 PE=2 SV=1) HSP 1 Score: 1166.76 bits (3017), Expect = 0.000e+0 Identity = 608/1203 (50.54%), Postives = 821/1203 (68.25%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFG-----FPPVFPEIETPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQ---MSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ +VFE N + + K KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G E ET V E+ T I +K KGKKSKA AK+G KYQW IM+ G++DEEI KF+E ++W+ Y+PPL I ++KRLG+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTL+K+K+ +PYP L +K ++FLVAATLRPET++GQTNCW+ P ++Y+ ++ + IC ++AARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ Y I D VLPFEPV VI+IP +G AV +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ +I +G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y +E WK T CL + TF +E RRNFEA L L E+ACSR+YGLGT +PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG+L G++ + GI MT + W+YV + + KLD L++EF +WYPVDLRVSGKDLVPNHL+YYL+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP + +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G VDE L +YL ++H+ R + ++ + I++AK+YPPWQ +S+L + +++ KLPDNK + S L PELKK MKK M + I+ + + L+ E DEK+V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F + P V ++++VNP +G S +IEI GD+ ++ RR+ I+D + V+L F D R +P+ + + PI +A F+V I + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKEIQQKWDTERVFEVNASSLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEDEEEETNVKTED-TRIK-DKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRLGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETLFGQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQAE-SPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAK--EKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPANTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAVEGMHRELVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVDEVLIHSSQYLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFEANNR--KLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQL-EFDEKAVLMENIVYLTNSLELE--HIEVKFASEAED-KIREDCCPGKPLNVFRI--------EPGV---------------SISLVNPQPSNGHFSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEHTEKTPISEHAVFNVDLMSKKIHLTENGIRVDIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Match: sp|Q09996|SYLC_CAEEL (Leucine--tRNA ligase OS=Caenorhabditis elegans OX=6239 GN=lars-1 PE=3 SV=2) HSP 1 Score: 1076.62 bits (2783), Expect = 0.000e+0 Identity = 563/1108 (50.81%), Postives = 738/1108 (66.61%), Query Frame = 3
Query: 186 KLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKT---EINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKH--GVLICVERAARNMAYQEILTDQPGEV---IILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESK-PNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMG---DYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXH------NAAIIWIAKSYPPWQMSILDSLIDMSD-KEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECS-DEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFS 3449
K+ +++IE + Q+ WE+ K FEA+ D K KY VTFP+PYMNG LHLGH FS SKCEF+ G++RL+GK L+ FGFHCTGMPIK+ ADKLKREM+ FG+PP FPE EE + EI +K KGKKSK VAK+G KYQWQIM+ G+ DEEIK+F++ ++W+ Y+PP I ++K++G+K DWRRSFITTD NP++DSFVRWQF L+ KI FGKR TI+SP D QPCMDHDR+SGEGVGPQEYTLIK+K+ P PQ L IK+D++LVAATLRPETMYGQTNC++HP I+Y +T++ V + R+AR M+YQ LT + G+V + L K G +++G L APL Y+ +Y LPM +IK +KGTG+VTSVPSDSPDD+AAL DLK+K+ R Y + D VLPFEPV +I I G AV+ KI+SQN+ DKL EAK++ Y GFY G +++GKYAG K++IQ DL GLA Y EPE++V+SRSG ECVVALCDQWYLNY + +WK+ K L + TF+DE RR E ++ LHEYACSRSYGLGT++PWD QYL+ESLSDSTIY AYYTVAH+LQ G+ DG S V +GI MT +W YV + + + P KL LR+EF YWYP+D+R SGKDL+ NHLTY LFNH AIWP ++ + WPK IRANGHLLLNNEKMSKSTGNF+T+ EAIEK+SADGMR++ ADAGD +EDANFV MADA +LRL++ IEW+KE++E + + +D VFAN +N I TE NY+ +K L+ GF E+Q+IRD YRE C G L+ F+E Q LILSPICPHI +YIW +L K I+N WP VDEKL+ R++ EFR + K A+I++AK YPPWQ +ILD L + G LPDNK+++ + + LKK KKAM +Q I+ + ++ + +P +D+ S++ N ++ L+LD ++ ++++DE D + ++ P+ P + F + P V R N++ V +VN D S
Sbjct: 10 KVAQLQEIEKSIQELWESKKAFEADA--RDDGKPKYLVTFPFPYMNGRLHLGHTFSASKCEFAAGFQRLQGKEVLFPFGFHCTGMPIKACADKLKREMQDFGYPPNFPEDVVEEVKEEVSAVDEIIKDKSKGKKSKLVAKTGNAKYQWQIMKSLGLCDEEIKEFSDPNHWLYYFPPHCIADLKKMGLKADWRRSFITTDVNPYFDSFVRWQFNLLRAAKKIDFGKRYTIYSPKDGQPCMDHDRASGEGVGPQEYTLIKLKVLDPKPQALSHIKEDIYLVAATLRPETMYGQTNCYLHPDIQYSVFYATENEKQVFVATARSARIMSYQG-LTKENGKVNYVLGLEKIAGSKILGAPLSAPLAKYERVYALPMLTIKDDKGTGVVTSVPSDSPDDFAALSDLKKKKPLREKYGLTDEMVLPFEPVPIIKIEGLGDLAAVEMCSRLKIESQNEKDKLEEAKKEVYLKGFYDGVMLVGKYAGKKTADVKKVIQDDLTAEGLATKYVEPEKKVMSRSGDECVVALCDQWYLNYGEAEWKAAAKKVLEPLRTFNDETRRGLETTVDWLHEYACSRSYGLGTKLPWDTQYLIESLSDSTIYNAYYTVAHLLQQGAFDG-SVVGPAGIKADQMTDASWSYVFLGEIYDSKTM-PVEEEKLKSLRKEFMYWYPIDMRASGKDLIGNHLTYLLFNHAAIWPTDTSK-WPKGIRANGHLLLNNEKMSKSTGNFMTLEEAIEKFSADGMRLSLADAGDGLEDANFVYAMADAAILRLFTMIEWIKEMIEQRDAGLLRKDAKKFADRVFANEMNSLIAATEQNYEATNFKDALKTGFFEYQAIRDTYRELCAGIDEPMSESLVFRFIETQMLILSPICPHIAEYIW-QLLGKDGLIVNAPWPTVDPVDEKLAIGARFITESLAEFRARLKTYMTPKKKALKEIPEVPTEAVIYVAKEYPPWQKTILDILEKQAKANNGALPDNKAISQLIGKEESLKKFAKKAMPFVQMIKERFEQKGVSALASSSP-VDQTSILNENIDFIMNALDLD--RVTIRHTDEEGIDANIVETTVPLVPMLNFT------PNRPTIKLVARNVQICNAMFDVDVPIVNGDSVS 1101
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Match: sp|Q54N83|SYLC_DICDI (Leucine--tRNA ligase, cytoplasmic OS=Dictyostelium discoideum OX=44689 GN=leuS PE=3 SV=1) HSP 1 Score: 916.761 bits (2368), Expect = 0.000e+0 Identity = 486/1041 (46.69%), Postives = 681/1041 (65.42%), Query Frame = 3
Query: 180 TAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKN-KYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLN--XXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDD---VFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDE--QWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPE----LVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXX-------XXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGK--LPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTP-EIDEKSVIESNFRYMAKTLNL 3236
TAKL+ ++ E Q +WE++K FE + + D ++ KY TFPYPYMNG LH+GH F+++K EF ++RL GK L+ F FHCTGMPIK+ ADKLK+E+E FG PPVFP IE E T + + K KK+KAVAKSGG YQW+IM+ G++DEEI F ++ YW+ Y+PP +++K LG+ VDWRRSFITTD N +YDSFVRWQF LK L K+ +GKR +I+S ID+Q C DH+R+ GEGVGPQ YTLIK+++ +P P+CL++I ++LV TLRPETMYGQTNCWI PT +Y A + + +C ER+ARNM+YQ++ T + GE L+KF G +++G AL+APL +Y LPM +I +NKGTG+VTSVPSDSPDDYA+L+DLK K R+ + I+D VLPFE V +IDIP Y + AV+ ++ IKSQND L +AK+ CY+ GF G + +G YAG V + K+II+ +++ SG A++YSEP +V+SRSG ECVVAL DQWY+NY D+ +WK+ T L + +S E ++ FE L ++++ACSRS+GLGT +PWDE++L+ESLSDSTIYMA+YTVAH+LQG + G S+GIT MT W+YVL G PE KL L++EF YWYPVD+RVSG DL+ NHLT++L+ H AI+ + ++ PK+IRANG + LN EKMSKSTGNFLT+ +++ K+SADG R+A ADAGDSIEDANFV+ A LL+L++ I+WV+E ++S R+GPL D +F + IN I E+E Y++ ++ L L F + Q+ RD Y+ T + H DL+ F+E+Q L++ PI PH ++ ++L K +I++ WP G +D + + Y+ + FR + K+K + + + I ++KSYP WQ +L+ L + +++ K DN ++ L E+K K M + S E ++ L+T DE S + N Y+ KTL L
Sbjct: 3 TAKLDFVRAYEKEVQNKWESDKQFEIDALDAPDAEHPKYLATFPYPYMNGRLHVGHVFTITKAEFMCQFQRLMGKRVLFPFAFHCTGMPIKACADKLKKEIEQFGCPPVFPVIEEKPIQEVTTAVKEDPLSFKSKKTKAVAKSGGAVYQWKIMQSLGISDEEIPMFADSAYWLNYFPPHCESDLKLLGVGVDWRRSFITTDVNGYYDSFVRWQFESLKALGKVKYGKRYSIWSTIDDQQCADHERAQGEGVGPQNYTLIKLEVVEPIPECLKEIHSQGKKIYLVPGTLRPETMYGQTNCWILPTGKYGAFEMANGDIFVCTERSARNMSYQQMTTGK-GEYKCLAKFEGSDILGAALKAPLAINPIVYVLPMLTIDENKGTGVVTSVPSDSPDDYASLQDLKAKAPLRAKFSIKDEWVLPFEVVPIIDIPGYSNESAVRAYKDLGIKSQNDRALLDQAKDLCYQKGFNDGVMSVGPYAGRKVSEVKKIIKDEMVASGQAVDYSEPTSKVVSRSGDECVVALSDQWYINYGDDDIEWKNQTIKQLESMEFYSAETKKKFEIALGWMNQWACSRSFGLGTHLPWDEKFLIESLSDSTIYMAFYTVAHLLQGDVNGSKPG--SAGITPKQMTSACWDYVL------MGKPYPEGCEVSEEKLKELKKEFTYWYPVDIRVSGADLIQNHLTFFLYTHAAIFEK---KFQPKSIRANGFVNLNGEKMSKSTGNFLTLVDSVAKFSADGTRVALADAGDSIEDANFVDQTAVTSLLKLHTQIQWVQETLDSIDKFRSGPLDRIQDTIFESEINNIIVESEKAYQKTNFRDALHLVFFDLQNARDHYKVTTLDQMHKDLVLRFIEVQALLIYPIAPHFAQKLF-NMLGK-GNILSAGWPKAGAIDYEALKKNNYVQQTIYNFRMKLQVYQKAKLKGKPAGTKAIPDQSTIIVSKSYPKWQQDVLEYLATIYNEDSKSFTKDNNAIAEELLSREEMKPHKKNLMGFVASAIQNVKESGKDA--LQTSLSFDETSTLTDNIDYICKTLEL 1027
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Match: A0A2Y9E0T2 (leucine--tRNA ligase, cytoplasmic OS=Trichechus manatus latirostris OX=127582 GN=LOC101349569 PE=3 SV=1) HSP 1 Score: 1199.88 bits (3103), Expect = 0.000e+0 Identity = 620/1199 (51.71%), Postives = 824/1199 (68.72%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVA-IEEKTE--INLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLID-MSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVAD-KISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGTAK++ +K IE Q++W+ KVFE N + + K+KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK+ L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E I KTE I +K KGKKSKA AK+G KYQW IMR G++DEEI KF+E ++W+ Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLI++K+ +PYP L +K ++FLVAATLRPETM+GQTNCW+ P ++Y+ ++ + IC +RAARNMAYQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD AALRDLK+K+ R+ Y I D VLPFEPV VI++P +G AV +E KI+SQND +KL EAKEK Y GFY G +++ ++ G VQ K+ IQ +I G A Y EPE+QV+SRS ECVVALCDQWYL+Y +E WK T CL + TF +E RRNFEA L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YTVAH+LQGG+L G+ G + I MT D W+Y+ + P+ KLD L++EF +WYPVDLRVSGKDLVPNHL+YYL+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT+++AI+K+SADGMRMA ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP S +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H +L+ F+E+Q L+L+P CPH+ ++IWT +L KP SIM SWP+ G VDE L +YL ++H+ R + ++ + I++AK+YPPWQ + L L + GKLPDNK + S L+ PELKK MKK M + I+ + V L+ E DE++V+ N Y+ +L L+ +E+K++ E D K+ + CCP +P F ++ P + V++VNP SG S +IEI GD+ ++ RR+ I+D + V+L F D R IP+ + + PI +A F V + I + NG+ IG+
Sbjct: 4 RKGTAKVDFLKKIEKEIQQKWDAEKVFEVNASDLEKQSSKSKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKSCLFPFGLHCTGMPIKACADKLKREIELYGCPPEFPDEEEEEEEINVKTEDIIIKDKAKGKKSKATAKAGSSKYQWGIMRSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIRLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIGFETVTGDIFICTQRAARNMAYQGFTKDD-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEVPGFGSLSAVTICDELKIQSQNDREKLAEAKEKLYLKGFYDGVMLVDEFKGEKVQDVKKTIQKKMIDMGDAFIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCEETRRNFEATLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNLHGQ-GESPLDIRPQQMTKDVWDYIFFKEAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDK-WPTAVRANGHLLLNSEKMSKSTGNFLTLTQAIDKFSADGMRMALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVANWDSLRSGPASTFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRELVFWFIEVQTLLLTPFCPHLCEHIWT-LLGKPGSIMKASWPVAGPVDEALIRSSQYLMEVAHDLRLRLKNYMMPARGKKTDKQPPQRPSHCTIYVAKNYPPWQHTTLSVLRNHFEANSGKLPDNKVIASELANLPELKKYMKKVMPFVAMIKENLEKLGPRVLDLQL-EFDEQAVLMENIVYLTNSLELE--HIEVKFASEAED-KVKEDCCPGKPLNVF-------RTEPGVL----------------VSLVNPQPSSGHFSTKIEIRQGDNHDSIIRRLMKMDRGIKDLSRVKLMRFDDPLLGPRQIPVLGKEYSEKTPISEHAVFHVDLTSKKIHLTENGLKADIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Match: A0A2J7PZ40 (Leucine--tRNA ligase, cytoplasmic OS=Cryptotermes secundus OX=105785 GN=Lars PE=3 SV=1) HSP 1 Score: 1199.88 bits (3103), Expect = 0.000e+0 Identity = 602/1203 (50.04%), Postives = 802/1203 (66.67%), Query Frame = 3
Query: 165 MNRKGTAKLNTIKDIEVAKQKEWENNKVFEAN-PIYGKDKKN-KYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEE-KTEINLNXXXXXXXXXXXXXXGF-KYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDD-VFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHG--VLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRE-TCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEF----------RXXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDEC-SDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATF--SVSKSGISFSVNGVAHRIG 3710
++RKGT K+ ++ IE Q WE K++E + P+ K + K+F TFP+PYMNG LHLGH FSLSKCEF+ Y+RLKGK L+ FGFHCTGMPIK+ +DKLKREME FGFPP FP V EE K + + K G KYQWQIM+ G+ D+EIKKF + +W+ ++PPL + +++R+GI VDWRR+FITTD+NPF+D FVRWQFL+LK NK+M+GKR T+FSP DNQPCMDHDRS+GEGVGPQEYTLIKMKL +P+ L +K VFLVAATLRPETMYGQTNCW+ P ++Y+A +T V IC R+ARNMAYQ T + G++ +L + G+++MG ALQAPLT+ IYTLPM +IK++KGTG+VTSVPSDSPDDYAAL DLK+K+ R Y IED VLPFEP+ +ID+P+YG AV E+ KI+SQND DKL EAK+ Y GFY G +++G + G VQ K+ +Q LI A+ Y EPE+Q+ISRSG ECVVALCDQWYL+Y +E+WK+ LN++NT+ +EV++NF A L LHEYACSR+YGLGT++PWDE++L+ESLSDSTIYMA+YTVAH+LQGG+ +G + NS GI MTP+ W Y+ D N N LD +RREF YWYPVDLR SGKDL+ NHLT++++NHCA+WP++ + WP IRANGHLLLN+ KMSKS GNFLT+SEA+EK+SADGMR AD+GDS+EDANFVE ADAG+LRLY+FIEWVKE+ K R GP +D VF++ IN I ET+ NY++M++K L+ GF E Q+ RD+YRE T + H DL+ F+++Q L+LSP+CPH+ +++W ++L + SI++E WPI G +DE L YL +H F RK + SE+ N A IW+AK +P WQ ++L +L + DK LPDNK + S LS+ PELKK MK+ M Q+ R K + L T E DE V+ + Y+ T LD+ +ELKYSD + E++ + CCP P I F V P ++M T++NP SG +H + + DGD+ + ++ + D +++L+ + D + R +P + + I+ NA F +V+K I +VNG + +G
Sbjct: 5 LDRKGTFKVEYLRKIEQDVQARWEEEKIYEVDAPVEPKKSLDEKFFCTFPFPYMNGRLHLGHTFSLSKCEFAARYQRLKGKRVLFPFGFHCTGMPIKACSDKLKREMEEFGFPPEFPATAFEVEPEESKADAVVKDKSKGKKSKAVAKSGSGKYQWQIMQSLGLCDDEIKKFADASHWLDHFPPLAVKDLRRIGIHVDWRRTFITTDSNPFFDQFVRWQFLQLKARNKVMYGKRYTVFSPRDNQPCMDHDRSTGEGVGPQEYTLIKMKLLEPFTSKLSSLKGKPVFLVAATLRPETMYGQTNCWVRPDLQYIAFSTTTGPGEVFICTRRSARNMAYQG-FTREEGKLDVLLELTGQDIMGVALQAPLTSNTKIYTLPMLTIKEDKGTGVVTSVPSDSPDDYAALLDLKKKQALREKYGIEDEMVLPFEPIPIIDVPDYGSLSAVTLYEKLKIQSQNDKDKLQEAKDLIYLKGFYDGVMLVGDFKGKKVQDVKKALQKQLIDKYEAVTYYEPEKQIISRSGDECVVALCDQWYLDYGEERWKAQAVKVLNRMNTYHEEVKKNFMATLNWLHEYACSRTYGLGTKLPWDEKWLIESLSDSTIYMAFYTVAHLLQGGTFNG-NKTNSFGIKAEQMTPEVWNYIFYKDAEFPANTNIS-KASLDVMRREFEYWYPVDLRCSGKDLIQNHLTFFIYNHCALWPDDESK-WPLGIRANGHLLLNSAKMSKSEGNFLTLSEAVEKFSADGMRFCLADSGDSVEDANFVESTADAGILRLYTFIEWVKEVQNLKATFRVGPADTFNDKVFSSEINLKIRETDDNYQKMLFKEALRTGFFELQASRDKYRELTLVEGMHKDLVIRFIKVQALLLSPVCPHVAEHVW-ELLGEKRSILHEQWPIAGPIDEVLVKSSCYLMEAAHMFRIFLKNHMQPRKSNKVTVSGSVSEKPNQATIWVAKKFPSWQATVLMTLKQLLDKTAYLPDNKVIASELSKKPELKKYMKRVMPFAQATREKIDTVGVQALNL-TLEFDELEVLSRSIVYLKST--LDVESIELKYSDSAEATERIREDCCPGIPYIAFTV-------------CPSMSM----------TLINPQPQSGHFTHVVSVRDGDNVAKLTAQLTRADQLIDPNSIQLWRYDDPELGPRKMPAFNSPTQGVVRIEDNAVFCVNVAKKNIELAVNGTRYPVG 1176
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Match: A0A481ADW1 (Leucine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 PE=3 SV=1) HSP 1 Score: 1196.8 bits (3095), Expect = 0.000e+0 Identity = 608/1202 (50.58%), Postives = 820/1202 (68.22%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVA-IEEKTE-INLNXXXXXXXXXXXXXXGF-KYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQ---MSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGT K++ +K IE Q++W+ KVFE N + + K+KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E I KTE I L K + G KYQW IM+ G++DEEI KF+E ++W++Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIK+K+ +PYP L +K +VFLVAATLRPETM+GQTNCW+HP I+Y+ ++ + IC RAARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD+AA RDLK+K+ R+ Y I D VLPFEPV +I+IP +G+ AV +E K++SQND +KL EAKEK Y GFY G +++ + G VQ K+ I++ +I +G A Y EPE+QV+SRS ECVVALCDQWYL+Y +E+WK T CL + TF +E RRNFEA L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YT AH+LQGG + G++ + GI MT + W+Y+ + P+ KLD L++EF +WYPVDLRVSGKDL+PNHL+Y+L+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT++EA++KYSADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP + +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G VDE L +YL ++H+ R + ++ + I++AK YP WQ +S+L S + S GKLPDNK + S L PELKK MKK M + I+ + V L+ E DE++V+ N Y+ +L L+ ++E+K++ E D K+ + CCP +P F ++ P + V++VNP FSG S +IEI GD+ +V RR+ D+ I+D + V+L F D R +P+ + + PI A F V + + + NG+ IG+
Sbjct: 4 RKGTTKVDFLKKIEKEIQQKWDTEKVFEVNASNLEKQTSKDKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKTCLYPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEEINAKTEDIILKDKAKGKKSKASAKTGSSKYQWDIMKSLGLSDEEIVKFSEAEHWLEYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKLKVLEPYPCKLSGLKGKNVFLVAATLRPETMFGQTNCWVHPEIKYIGFETVNGDIFICTPRAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDFAAFRDLKKKQALRAKYGIRDDMVLPFEPVPIIEIPGFGKLSAVTLCDELKVQSQNDREKLAEAKEKLYLKGFYDGIMLVDGFEGQKVQDVKKSIRNRMIDTGDAYAYMEPEKQVMSRSSDECVVALCDQWYLDYGEEKWKEQTCQCLKNLETFCEETRRNFEATLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTAAHLLQGGDIRGQAE-SPLGIRPQQMTKEVWDYIFFKEAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRVSGKDLIPNHLSYFLYNHVAMWPEESDK-WPVAVRANGHLLLNSEKMSKSTGNFLTLTEALDKYSADGMRLALADAGDTVEDANFVEAMADAGVLRLYTWVEWVKEMVANWDSLRSGPANTFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVDESLIRSSQYLMEVAHDLRLRLKNYMTPAKGKKPDKQPPQKPSHCTIYVAKDYPSWQHVTLSVLRSHFETSS--GKLPDNKVIASELGNLPELKKYMKKVMPFVAMIKENLEKTGPRVLDLQL-EFDEQAVLMENIVYLTNSLELE--RIEVKFASEAED-KVREDCCPGKPLNVF-------RTEPGVL----------------VSLVNPQPFSGHFSAKIEIRQGDNRDSVIRRLMKVDR-GIKDLSKVKLMRFDDPLLGPRRVPVLGKEHTEKTPISEQAVFHVDLTSKKVHLTENGLRADIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Match: A0A481AHZ8 (Leucine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 PE=3 SV=1) HSP 1 Score: 1196.42 bits (3094), Expect = 0.000e+0 Identity = 608/1202 (50.58%), Postives = 820/1202 (68.22%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVA-IEEKTE-INLNXXXXXXXXXXXXXXGF-KYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQ---MSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGT K++ +K IE Q++W+ KVFE N + + K+KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E I KTE I L K + G KYQW IM+ G++DEEI KF+E ++W++Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIK+K+ +PYP L +K +VFLVAATLRPETM+GQTNCW+HP I+Y+ ++ + IC RAARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD+AA RDLK+K+ R+ Y I D VLPFEPV +I+IP +G+ AV +E K++SQND +KL EAKEK Y GFY G +++ + G VQ K+ I++ +I +G A Y EPE+QV+SRS ECVVALCDQWYL+Y +E+WK T CL + TF +E RRNFEA L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YT AH+LQGG + G++ + GI MT + W+Y+ + P+ KLD L++EF +WYPVDLRVSGKDL+PNHL+Y+L+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT++EA++KYSADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP + +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G VDE L +YL ++H+ R + ++ + I++AK YP WQ +S+L S + S GKLPDNK + S L PELKK MKK M + I+ + V L+ E DE++V+ N Y+ +L L+ ++E+K++ E D K+ + CCP +P F ++ P + V++VNP FSG S +IEI GD+ +V RR+ D+ I+D + V+L F D R +P+ + + PI A F V + + + NG+ IG+
Sbjct: 4 RKGTTKVDFLKKIEKEIQQKWDTEKVFEVNASDLEKQTSKDKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKTCLYPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEEINAKTEDIILKDKAKGKKSKASAKTGSSKYQWDIMKSLGLSDEEIVKFSEAEHWLEYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKLKVLEPYPCKLSGLKGKNVFLVAATLRPETMFGQTNCWVHPEIKYIGFETVNGDIFICTPRAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDFAAFRDLKKKQALRAKYGIRDDMVLPFEPVPIIEIPGFGKLSAVTLCDELKVQSQNDREKLAEAKEKLYLKGFYDGIMLVDGFEGQKVQDVKKSIRNRMIDTGDAYAYMEPEKQVMSRSSDECVVALCDQWYLDYGEEKWKEQTCQCLKNLETFCEETRRNFEATLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTAAHLLQGGDIRGQAE-SPLGIRPQQMTKEVWDYIFFKEAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRVSGKDLIPNHLSYFLYNHVAMWPEESDK-WPVAVRANGHLLLNSEKMSKSTGNFLTLTEALDKYSADGMRLALADAGDTVEDANFVEAMADAGVLRLYTWVEWVKEMVANWDSLRSGPANTFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVDESLIRSSQYLMEVAHDLRLRLKNYMTPAKGKKPDKQPPQKPSHCTIYVAKDYPSWQHVTLSVLRSHFETSS--GKLPDNKVIASELGNLPELKKYMKKVMPFVAMIKENLEKTGPRVLDLQL-EFDEQAVLMENIVYLTNSLELE--RIEVKFASEAED-KVREDCCPGKPLNVF-------RTEPGVL----------------VSLVNPQPFSGHFSAKIEIRQGDNRDSVIRRLMKVDR-GIKDLSKVKLMRFDDPLLGPRRVPVLGKEHTEKTPISEQAVFHVDLTSKKVHLTENGLRADIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Match: A0A480JIP6 (Leucine--tRNA ligase, cytoplasmic OS=Sus scrofa OX=9823 PE=3 SV=1) HSP 1 Score: 1196.42 bits (3094), Expect = 0.000e+0 Identity = 608/1202 (50.58%), Postives = 820/1202 (68.22%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP--IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVA-IEEKTE-INLNXXXXXXXXXXXXXXGF-KYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQ---MSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSV--SKSGISFSVNGVAHRIGE 3713
RKGT K++ +K IE Q++W+ KVFE N + + K+KYFVTFPYPYMNG LHLGH FSLSKCEF++GY+RLKGK L+ FG HCTGMPIK+ ADKLKRE+E +G PP FP+ E I KTE I L K + G KYQW IM+ G++DEEI KF+E ++W++Y+PPL I ++KR+G+KVDWRRSFITTD NP+YDSFVRWQFL L++ NKI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIK+K+ +PYP L +K +VFLVAATLRPETM+GQTNCW+HP I+Y+ ++ + IC RAARNM+YQ D G V ++ + +G+E++G +L APLT+YK IY LPM +IK++KGTG+VTSVPSDSPDD+AA RDLK+K+ R+ Y I D VLPFEPV +I+IP +G+ AV +E K++SQND +KL EAKEK Y GFY G +++ + G VQ K+ I++ +I +G A Y EPE+QV+SRS ECVVALCDQWYL+Y +E+WK T CL + TF +E RRNFEA L+ L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMA+YT AH+LQGG + G++ + GI MT + W+Y+ + P+ KLD L++EF +WYPVDLRVSGKDL+PNHL+Y+L+NH A+WPE SD+ WP +RANGHLLLN+EKMSKSTGNFLT++EA++KYSADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE+V + ++R+GP + +D VFA+ +N I +T+ NY++MM+K L+ GF EFQ+ +D+YRE + H DL+ F+E+Q L+L+P CPH+ ++IWT +L KP SIMN SWP+ G VDE L +YL ++H+ R + ++ + I++AK YP WQ +S+L S + S GKLPDNK + S L PELKK MKK M + I+ + V L+ E DE++V+ N Y+ +L L+ ++E+K++ E D K+ + CCP +P F ++ P + V++VNP FSG S +IEI GD+ +V RR+ D+ I+D + V+L F D R +P+ + + PI A F V + + + NG+ IG+
Sbjct: 4 RKGTTKVDFLKKIEKEIQQKWDTEKVFEVNASNLEKQTSKDKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKTCLYPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEEINAKTEDIILKDKAKGKKSKASAKTGSSKYQWDIMKSLGLSDEEIVKFSEAEHWLEYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKLKVLEPYPCKLSGLKGKNVFLVAATLRPETMFGQTNCWVHPEIKYIGFETVNGDIFICTPRAARNMSYQGFTKDN-GVVPVVKELMGEEILGASLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDFAAFRDLKKKQALRAKYGIRDDMVLPFEPVPIIEIPGFGKLSAVTMCDELKVQSQNDREKLAEAKEKLYLKGFYDGIMLVDGFEGQKVQDVKKSIRNRMIDTGDAYAYMEPEKQVMSRSSDECVVALCDQWYLDYGEEKWKEQTCQCLKNLETFCEETRRNFEATLDWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAFYTAAHLLQGGDIRGQAE-SPLGIRPQQMTKEVWDYIFFKEAPFPKTQIPK--EKLDQLKQEFEFWYPVDLRVSGKDLIPNHLSYFLYNHVAMWPEESDK-WPVAVRANGHLLLNSEKMSKSTGNFLTLTEALDKYSADGMRLALADAGDTVEDANFVEAMADAGVLRLYTWVEWVKEMVANWDSLRSGPANTFNDRVFASEMNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAIEGMHRDLVFRFIEVQTLLLAPFCPHLCEHIWT-LLGKPDSIMNASWPVAGPVDESLIRSSQYLMEVAHDLRLRLKNYMTPAKGKKPDKQPPQKPSHCTIYVAKDYPSWQHVTLSVLRSHFETSS--GKLPDNKVIASELGNLPELKKYMKKVMPFVAMIKENLEKTGPRVLDLQL-EFDEQAVLMENIVYLTNSLELE--RIEVKFASEAED-KVREDCCPGKPLNVF-------RTEPGVL----------------VSLVNPQPFSGHFSAKIEIRQGDNRDSVIRRLMKVDR-GIKDLSKVKLMRFDDPLLGPRRVPVLGKEHTEKTPISEQAVFHVDLTSKKVHLTENGLRADIGD 1169
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Cavefish
Match: lars1b (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:103037167]) HSP 1 Score: 1174.07 bits (3036), Expect = 0.000e+0 Identity = 612/1203 (50.87%), Postives = 817/1203 (67.91%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDK---KNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEIN-----LNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNP-ELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHN--------AAIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKI-SIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAKL+ ++ IE Q++WE K FE + + ++ KNKYFVTFPYPYMNG LHLGH F LSKCEFSMGY+RLKGK L+ FG HCTGMPIK+ ADKLKREME +G PP FP+ E A EEK + N +K KGKKSKA AK+GG K+QW IM+ G+ D++I KF ++W++Y+PPL + ++K++G+KVDWRRSFITTD NPFYDSFVRWQFL LK+ KI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +PYP L +K ++VFLVAATLRPETM+GQTNCW+ P ++Y+A ++ V I +R+ARNMAYQ T + G V ++ + +G++++GCAL APLT+YKTIY LPM +IK++KGTG+VTSVPSD+PDD AALRD+K+K+ R Y IED+ VLPFEPV +I+IP YG A +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y D++WK + L + TF DE R+NFEA L L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMAYYTVAH+LQGG L+G+ G + GI MT + W+Y+ P E + KL G EF YWYPVD R+SGKDLVPNHL+YYL+NH A+WPE+S + WPK +RANGHLLLN+EKMSKSTGNFLT+S+AI K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ ++ N+RTGP +D VF + +N I +TE +Y++MMYK L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ +Y WT +L K S+M SWP+ G VDE L +YL +H+ R + + +++ + +++AKSYPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L LD ++++ ++ E +DEK+ + CCP +P F + P V +V+++NP +G S I+I GDS ++ RR++ I+D + V+L F D R +P+ + + P+ + F +S + + S NG+ IG+
Sbjct: 4 RKGTAKLDFLRKIEQDIQQKWEKEKAFECDALTTAEEIKNKNKYFVTFPYPYMNGRLHLGHTFCLSKCEFSMGYQRLKGKRCLFPFGLHCTGMPIKACADKLKREMELYGTPPQFPDEEEDGA-EEKPKTNDEIIIKDKAKGKKSKAAAKAGGSKFQWDIMKSLGLPDKDIVKFANAEHWLEYFPPLAVEDLKKMGVKVDWRRSFITTDVNPFYDSFVRWQFLTLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKIVEPYPAKLSDLKGNNVFLVAATLRPETMFGQTNCWVRPDMKYIAFETANGDVFISTQRSARNMAYQG-FTKENGVVPVVKQIMGQDILGCALSAPLTSYKTIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDIKKKQALREKYGIEDHMVLPFEPVPIIEIPGYGNLSAPVVCDELKIQSQNDREKLAEAKEKVYLKGFYEGIMLVDGFKGQKVQDVKKPIQKMMVEKGEALIYMEPEKQVMSRSADECVVALCDQWYLDYGDKEWKQQAVNVLEPMETFCDETRKNFEATLAWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAYYTVAHLLQGGVLNGQ-GSSPLGIRPEQMTREVWDYIFFKTAPFPKTTIPKECLQKLKG---EFEYWYPVDARISGKDLVPNHLSYYLYNHVAMWPEDSGK-WPKAVRANGHLLLNSEKMSKSTGNFLTLSQAINKFSADGMRLALADAGDTVEDANFVETMADAGILRLYTWVEWVKEMIANQNNLRTGPADTFNDRVFVSEMNSGIVKTEQHYERMMYKEALKSGFFEFQAAKDKYRELAIEGMHRDLVFKFIENQTLLLAPICPHLCEYTWT-LLGKTGSLMKASWPVAGPVDEILIRSSQYLMETAHDLRLRLKAYLQPPKNKKGDNRPPGKPSHCTVYVAKSYPPWQHSALSLLGKHYKSNNGTLPDNKVIAMELGAMPELKKYMKRVMPFVAMIKDNLEKNGPRVLDLEL-EFDERAVLLENIVYLTNSLELD--QIDVLFASE-ADEKVKEDCCPGKPFSVF--------RSEPGV---------------SVSLLNPQPSNGLFSTRIDIRQGDSKDSIIRRLSKTSRGIKDLSKVKLMRFEDPVLGPRRVPVLGKEEQGKLPVSDKSVFHISLEEKKVHLSDNGLKVDIGD 1171
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Cavefish
Match: lars1b (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:103037167]) HSP 1 Score: 1174.07 bits (3036), Expect = 0.000e+0 Identity = 612/1203 (50.87%), Postives = 817/1203 (67.91%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDK---KNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEIN-----LNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNP-ELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHN--------AAIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKI-SIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAKL+ ++ IE Q++WE K FE + + ++ KNKYFVTFPYPYMNG LHLGH F LSKCEFSMGY+RLKGK L+ FG HCTGMPIK+ ADKLKREME +G PP FP+ E A EEK + N +K KGKKSKA AK+GG K+QW IM+ G+ D++I KF ++W++Y+PPL + ++K++G+KVDWRRSFITTD NPFYDSFVRWQFL LK+ KI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +PYP L +K ++VFLVAATLRPETM+GQTNCW+ P ++Y+A ++ V I +R+ARNMAYQ T + G V ++ + +G++++GCAL APLT+YKTIY LPM +IK++KGTG+VTSVPSD+PDD AALRD+K+K+ R Y IED+ VLPFEPV +I+IP YG A +E KI+SQND +KL EAKEK Y GFY G +++ + G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y D++WK + L + TF DE R+NFEA L L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMAYYTVAH+LQGG L+G+ G + GI MT + W+Y+ P E + KL G EF YWYPVD R+SGKDLVPNHL+YYL+NH A+WPE+S + WPK +RANGHLLLN+EKMSKSTGNFLT+S+AI K+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ ++ N+RTGP +D VF + +N I +TE +Y++MMYK L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ +Y WT +L K S+M SWP+ G VDE L +YL +H+ R + + +++ + +++AKSYPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L LD ++++ ++ E +DEK+ + CCP +P F + P V +V+++NP +G S I+I GDS ++ RR++ I+D + V+L F D R +P+ + + P+ + F +S + + S NG+ IG+
Sbjct: 4 RKGTAKLDFLRKIEQDIQQKWEKEKAFECDALTTAEEIKNKNKYFVTFPYPYMNGRLHLGHTFCLSKCEFSMGYQRLKGKRCLFPFGLHCTGMPIKACADKLKREMELYGTPPQFPDEEEDGA-EEKPKTNDEIIIKDKAKGKKSKAAAKAGGSKFQWDIMKSLGLPDKDIVKFANAEHWLEYFPPLAVEDLKKMGVKVDWRRSFITTDVNPFYDSFVRWQFLTLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKIVEPYPAKLSDLKGNNVFLVAATLRPETMFGQTNCWVRPDMKYIAFETANGDVFISTQRSARNMAYQG-FTKENGVVPVVKQIMGQDILGCALSAPLTSYKTIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDIKKKQALREKYGIEDHMVLPFEPVPIIEIPGYGNLSAPVVCDELKIQSQNDREKLAEAKEKVYLKGFYEGIMLVDGFKGQKVQDVKKPIQKMMVEKGEALIYMEPEKQVMSRSADECVVALCDQWYLDYGDKEWKQQAVNVLEPMETFCDETRKNFEATLAWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAYYTVAHLLQGGVLNGQ-GSSPLGIRPEQMTREVWDYIFFKTAPFPKTTIPKECLQKLKG---EFEYWYPVDARISGKDLVPNHLSYYLYNHVAMWPEDSGK-WPKAVRANGHLLLNSEKMSKSTGNFLTLSQAINKFSADGMRLALADAGDTVEDANFVETMADAGILRLYTWVEWVKEMIANQNNLRTGPADTFNDRVFVSEMNSGIVKTEQHYERMMYKEALKSGFFEFQAAKDKYRELAIEGMHRDLVFKFIENQTLLLAPICPHLCEYTWT-LLGKTGSLMKASWPVAGPVDEILIRSSQYLMETAHDLRLRLKAYLQPPKNKKGDNRPPGKPSHCTVYVAKSYPPWQHSALSLLGKHYKSNNGTLPDNKVIAMELGAMPELKKYMKRVMPFVAMIKDNLEKNGPRVLDLEL-EFDERAVLLENIVYLTNSLELD--QIDVLFASE-ADEKVKEDCCPGKPFSVF--------RSEPGV---------------SVSLLNPQPSNGLFSTRIDIRQGDSKDSIIRRLSKTSRGIKDLSKVKLMRFEDPVLGPRRVPVLGKEEQGKLPVSDKSVFHISLEEKKVHLSDNGLKVDIGD 1171
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005898.1 (pep scaffold:Pmarinus_7.0:GL480199:186:9945:1 gene:ENSPMAG00000005301.1 transcript:ENSPMAT00000005898.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 485.337 bits (1248), Expect = 5.250e-158 Identity = 261/630 (41.43%), Postives = 386/630 (61.27%), Query Frame = 3
Query: 1881 LGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNES-WPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA---------AIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRV--ADK-ISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVSKS------GISFSVNGVAHRIGE 3713
+GTR+PWDE++L+ESLSDSTIYMA+YTV H+LQGG+LDG GV+ GI DM+ W+YVL D V ++ + KLD LRREF +WYP+DLRVSGKDLVPNHLTYYL+NH A+WP++S+ WP+ +RANGHLLLN+EKMSKSTGNFLT+SEAI K+SADGMR+A ADAGD++EDANFVE +A++G+LRL++++EW +++++S R GP S +D VF + +N + +TE Y++MM+K L+ GF EFQ+ RDRYRE + + DL+ F+E+Q L+L+P+CPH+ +++W +L KP S++ E+ WP+ DE L Y+ +H+ R + S S + I ++AK+YPPWQ L +L GKLPDNK ++ L PELKK +K+ M + I+ + L+ E DE++V+ N Y+ TL +D ++ + ++ E +++++ D C P +P + F V P V +V +VN +L +G S + + DGD + RR+ +D+ I + + V L ++D R IP M PI R+A F ++ + GI S+ G +H +G+
Sbjct: 1 VGTRLPWDERWLIESLSDSTIYMAFYTVCHLLQGGTLDGH-GVSPLGIRPEDMSCAVWDYVLFPDAPVPDSVISK--EKLDLLRREFQFWYPMDLRVSGKDLVPNHLTYYLYNHVAMWPKHSEM-WPRAVRANGHLLLNSEKMSKSTGNFLTLSEAISKFSADGMRLALADAGDTVEDANFVESVAESGVLRLHAWVEWARDVLQSPHGQRLGPASSFNDRVFISEMNAGVHKTEKLYEKMMFKEALKTGFFEFQACRDRYRELALDGMNRDLLLRFIELQTLLLAPVCPHVCEHVW-GLLGKPGSVVREARWPVVDAPDEILLRSAEYMREATHDARIRLKVSLASTHSRSPSPLQPHRPPSHCIFYVAKNYPPWQHVTLTTLQRHYQANGKLPDNKQISVELGAKPELKKHLKRVMPFVVMIKDNLERQGPRALDLQL-EFDERAVLMENITYLTTTLEVD--EVRVLFASE-AEQRIRDECRPGKPHVNFYV--------EPGV---------------SVMLVNHELSNGHFSTRVTVHDGDCTDRIIRRLMKSDRGIKMPVLSQVSLLRYLDPNMGPRTIPHLGSPMHGTAPIPRDALFHITGTPSDGGCGIRVSIGGESHEVGD 598
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000019.1 (pep scaffold:Pmarinus_7.0:GL486658:1337:8958:-1 gene:ENSPMAG00000000017.1 transcript:ENSPMAT00000000019.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 336.65 bits (862), Expect = 1.090e-106 Identity = 164/283 (57.95%), Postives = 202/283 (71.38%), Query Frame = 3
Query: 891 MDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIK-DDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQW 1736
MDHDR +GEGVGPQEYTLIKMKL +P+P L + + VFLVAATLRPETM+GQTNCW+ P + YVA ++ V +C RAARNM+YQ T G V L++ G +LMG AL APL ++ IYTLPM ++K++KGTG+VTSVPSDSPDD AALRDLKRK R Y I D VLPFEPV +I++P G AV ++E I SQN+ D+L AKE+ Y GFY G +++ Y G VQ K++IQ LI+ G A+ Y EPERQV+SRSG ECVVALCDQW
Sbjct: 1 MDHDRQTGEGVGPQEYTLIKMKLLEPFPAKLSHLAGESVFLVAATLRPETMFGQTNCWLGPDVRYVAFRTACGSVFVCTARAARNMSYQG-FTTADGHVDKLAQLTGVDLMGAALSAPLCSFPVIYTLPMLTVKEDKGTGVVTSVPSDSPDDIAALRDLKRKSALREKYGITDAMVLPFEPVPIIEVPGLGPLAAVTVLDEMGISSQNERDRLALAKERVYLKGFYEGVMLVAGYEGCRVQDVKKVIQGKLISDGHAVLYMEPERQVMSRSGDECVVALCDQW 282
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Sea Lamprey
Match: mars2 (methionyl-tRNA synthetase 2, mitochondrial [Source:ZFIN;Acc:ZDB-GENE-111201-1]) HSP 1 Score: 53.5286 bits (127), Expect = 2.927e-7 Identity = 36/108 (33.33%), Postives = 51/108 (47.22%), Query Frame = 3
Query: 2148 WYPVDLRVSGKDLVPNHLTYYLFNHCAIWPE---NSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANF----VEDMADAGL 2450
W+P DL V GKD++ H Y WP + P+ + + H + KMSKS GN + +E I +YSADG+R G D ++ VE M +A L
Sbjct: 254 WWPCDLHVLGKDILKFHALY--------WPAFLMAAGLEPPRRLLVHSHWTVAGRKMSKSLGNSVDPNEDINRYSADGLRYFLLRQGVPESDGDYYPEKVEKMLNAEL 353
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Sea Lamprey
Match: mars2 (methionyl-tRNA synthetase 2, mitochondrial [Source:ZFIN;Acc:ZDB-GENE-111201-1]) HSP 1 Score: 53.1434 bits (126), Expect = 3.141e-7 Identity = 36/105 (34.29%), Postives = 51/105 (48.57%), Query Frame = 3
Query: 2148 WYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANF----VEDMADAGL 2450
W+P DL V GKD++ H Y+ A E P+ + + H + KMSKS GN + +E I +YSADG+R G D ++ VE M +A L
Sbjct: 288 WWPCDLHVLGKDILKFHALYWPAFLMAAGLEP-----PRRLLVHSHWTVAGRKMSKSLGNSVDPNEDINRYSADGLRYFLLRQGVPESDGDYYPEKVEKMLNAEL 387
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Yeast
Match: CDC60 (Cytosolic leucyl tRNA synthetase; ligates leucine to the appropriate tRNA; human homolog LARS can complement yeast temperature-sensitive mutant at restrictive temperature [Source:SGD;Acc:S000006081]) HSP 1 Score: 770 bits (1987), Expect = 0.000e+0 Identity = 443/1058 (41.87%), Postives = 620/1058 (58.60%), Query Frame = 3
Query: 180 TAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKK------------NKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFG----FPPVFPEIETPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIK---MKLEKPYPQCLEQIKD-----DVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLP----FEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGK-VDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHN-------AAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVK-CNERSENV--SRLKTPEIDEKSVIESNFRYMAKTLNL 3236
TA+ + + IE QK W FE + +D+ K+ + YPYMNG +H GH F+LSK EFS+G+ER+ GK AL+ GFHCTGMPI + ADKLKRE E FG P E EK ++ K K KKSKA AK G KYQ++IM G+ EEI KF + YW+ Y+PPL ++ LG ++DWRRSF+TTDANP+YD+F+RWQ KLK KI FG+R TI+S D Q CMDHDR SGEGV PQEY +K ++ + ++ D + VAATLRPETMYGQT C++ PTIEY + I ERA +NM+YQ+ LT + G + GK +G + AP + Y + LPM ++ KGTG+VT VPS+SPDDY +DL L+K E Y + P E V ++ +YG A VEE KI+S D + L EAK+ YK +Y+G +I G Y G V++AK +++D+I +G A Y+EPE QV+SRSG +C+V+L DQWY++Y +E WK CL + F+ EV+ FE L+ L +A R+YGLGTR+PWDE+YLVESLSDSTIY ++YT+AH+L G GI+ MT + ++Y+ V P + L LRREF Y+YP+D+ +SGKDL+PNHLT++++ H A++P+ ++WPK IRANGHL+LNN KMSKSTGNF+T+ + +EK+ AD R+AFADAGD++EDANF E A+A +LRL++ EW +EI + + N+RTG ++ D+ F + +N IE+T Y YK L+ G +FQ+ RD YRE G H DLI ++E Q L+L+PI PH +YI+ ++L +S+ N +P K VD+ + YL + R+ Q K K + + I++S+P WQ ++ ++ E L DNK + + K MK+AM I ++ + NE+ E+V L+ EID N + A+ L +
Sbjct: 10 TARRDALIAIEKKYQKIWAEEHQFEIDAPSIEDEPITMDSEELHRTYPKFMSSMAYPYMNGVMHAGHCFTLSKVEFSIGFERMNGKRALFPLGFHCTGMPILACADKLKREAELFGKNFDNVPAEEEEIKEETPAEKDHEDVTKFKAKKSKAAAKKGRGKYQFEIMLQLGIPREEIIKFADAKYWLTYFPPLCESDCTSLGARIDWRRSFVTTDANPYYDAFIRWQMNKLKAAGKIKFGERYTIYSEKDGQACMDHDRQSGEGVTPQEYIGVKIEALEFADDAAKIIDSSSDLDKSKKFYFVAATLRPETMYGQTCCFVSPTIEY-GIFDAGDSYFITTERAFKNMSYQK-LTPKRGFYKPIVTVPGKAFIGTKIHAPQSVYPELRILPMETVIATKGTGVVTCVPSNSPDDYITTKDL--------LHKPEYYGIKPEWIDHEIVPIMHTEKYGDLTAKAIVEEKKIQSPKDKNLLAEAKKIAYKEDYYTGTMIYGPYKGEKVEQAKNKVKADMIAAGEAFVYNEPESQVMSRSGDDCIVSLEDQWYVDYGEESWKKQAIECLEGMQLFAPEVKNAFEGVLDWLKNWAVCRTYGLGTRLPWDEKYLVESLSDSTIYQSFYTIAHLLFKDYYGNEIG--PLGISADQMTDEVFDYIFQHQDDVKNTNIP--LPALQKLRREFEYFYPLDVSISGKDLIPNHLTFFIYTHVALFPK---KFWPKGIRANGHLMLNNSKMSKSTGNFMTLEQTVEKFGADAARIAFADAGDTVEDANFDESNANAAILRLFNLKEWAEEITK-ESNLRTGEITDFFDIAFEHEMNALIEKTYEQYALTNYKNALKYGLFDFQAARDYYREAS-GVMHKDLIARYIETQALLLAPIAPHFAEYIYREVLGNQTSVQNAKFPRASKPVDKGVLAALDYLRNLQRSIREGEGQALKKKKGKSAEIDASKPVKLTLLISESFPEWQSQCVE-IVRKLFSEQTLDDNKKVREHIE-----PKEMKRAMPFISLLKQRLANEKPEDVFERELQFSEIDTVKAAARNVKKAAQALKI 1042
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Yeast
Match: YNL247W_mRNA (Cysteinyl-tRNA synthetase; may interact with ribosomes, based on co-purification experiments; human gene CARS allows growth of the yeast haploid null mutant after sporulation of a heterozygous diploid [Source:SGD;Acc:S000005191]) HSP 1 Score: 48.521 bits (114), Expect = 6.446e-6 Identity = 29/78 (37.18%), Postives = 41/78 (52.56%), Query Frame = 3
Query: 2157 VDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFA 2390
+D+ G DL H L A + +Q W GHL + +KMSKS NF+TI EA++K+S +R+AFA
Sbjct: 381 IDIHSGGIDLAFPHHDNELAQSEARF---DNQQWINYFLHTGHLHIEGQKMSKSLKNFITIQEALKKFSPRQLRLAFA 455
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Nematostella
Match: EDO40441 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S766]) HSP 1 Score: 611.683 bits (1576), Expect = 0.000e+0 Identity = 295/504 (58.53%), Postives = 368/504 (73.02%), Query Frame = 3
Query: 612 YQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQI---------------KDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKS-TKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDD 2075
YQWQIM+ G+ EEI KF ETDYW+ Y+PPL ++K +G+K DWRRS+ITTD NP+YDSFVRW F LK+ K+ FGKR TIFSP D+QPCMDHDR SGEGVGPQEY +IKMK+ P+ + L +V+LVAATLRPETMYGQTNCW+ P ++Y+A ++ + V IC +RAARNM+YQ T + V IL+K G+++MG AL+APLT+ K IYTLPM +IK++KGTGIVTSVPSD+PDDYAALRD+++K D R Y I D LPF P+ +I++P YG CAVK E+ KIKSQND D L+EAKE YK GFY G +I+G++AG VQ+ K+++Q ++ +G A Y EPE+ VISRSG ECVVALCDQWYL+Y + W++ L+Q NTFS+E RRNF A L+ LHE+ACSRSYGLGTR+PWDEQYLVESLSDSTIY AYYTVAH+LQGG DG +G + GI MT W+YV D
Sbjct: 14 YQWQIMQSLGIPQEEIPKFAETDYWLSYFPPLAKEDLKSMGLKTDWRRSYITTDVNPYYDSFVRWHFWNLKERGKVKFGKRYTIFSPADDQPCMDHDRQSGEGVGPQEYNVIKMKVVPPFKEKLRYSVIPELFLSHANFVLEGKNVYLVAATLRPETMYGQTNCWVRPDMKYIAFETNVPNDVYICTQRAARNMSYQG-FTAKESHVNILAKLTGQDIMGIALEAPLTSNKIIYTLPMLTIKEDKGTGIVTSVPSDAPDDYAALRDIQKKPDFRKKYGITDEMALPFNPIPIINVPGYGDLCAVKACEDMKIKSQNDRDLLLEAKELSYKKGFYEGTMIVGEFAGQKVQEVKKLVQMKMLQAGDARIYMEPEKLVISRSGDECVVALCDQWYLDYGEPAWRAQATEALSQCNTFSEETRRNFVATLDWLHEHACSRSYGLGTRLPWDEQYLVESLSDSTIYNAYYTVAHLLQGGVFDGSAG-SPVGIMPEQMTKAVWDYVFFHD 515
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Nematostella
Match: EDO40444 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S771]) HSP 1 Score: 256.529 bits (654), Expect = 1.302e-76 Identity = 137/328 (41.77%), Postives = 196/328 (59.76%), Query Frame = 3
Query: 2373 MRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSLIDM-SDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITF 3329
MR+A ADAGD++EDANFVE MADAG+LRLY+F EW++E++ SK +RTGP + + D VF + IN+ I +TE NY+QM Y+ ++ GF+E Q+ RD+YRE C+ H DL+ F+E+Q L+LSPICPH+ + IW ++ K SI+N WP+ G VDE L YL +HEFR + K +Q +A ++++A S+PPWQ L +L + G PDN+ + + L + E+KK MKK M +Q +R ER + T +E V+ N Y+ K LDL LE+K S E D K+ + C P +P F
Sbjct: 1 MRLALADAGDTLEDANFVEKMADAGILRLYTFHEWIREMIASKDQLRTGPKTSYEDRVFESEINQAIRQTELNYEQMTYRDAVKTGFYELQASRDKYREMCLNGMHRDLVFRFIEVQTLLLSPICPHLCEDIW-KVIGKSGSILNADWPVAGDVDETLLKSAVYLTSSTHEFRLRIKNLLAPKGKKQKDAPPPAKPTHGLVYVASSFPPWQHVTLTTLKQLYHSNGGAFPDNRIIMNSLKDAAEVKKYMKKLMPFVQYVRSNV-ERDGPSAMDTTVPFNELEVLRENEGYLKKA--LDLVHLEIKPSSE-GDAKVQEECAPGKPFTVF 323
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Nematostella
Match: EDO40440 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S765]) HSP 1 Score: 146.362 bits (368), Expect = 6.888e-41 Identity = 72/119 (60.50%), Postives = 89/119 (74.79%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEAN-PIYGKD--KKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIE 518
RK TAK++ +K IE Q++WE K+FE + P G D KK K+F TFPYPYMNG LHLGH F+L+K F+ G++RLKGKN L+ F FHCTGMPIK+ ADKLKREME FG PP FP ++
Sbjct: 2 RKSTAKVDFLKGIETDVQQQWEKMKIFEIDAPDPGSDAAKKGKFFCTFPYPYMNGKLHLGHTFTLAK--FASGFQRLKGKNTLYPFAFHCTGMPIKACADKLKREMEQFGNPPRFPAVD 118
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Medaka
Match: lars1b (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:101154887]) HSP 1 Score: 1142.1 bits (2953), Expect = 0.000e+0 Identity = 591/1208 (48.92%), Postives = 798/1208 (66.06%), Query Frame = 3
Query: 171 RKGTAKLNTIKDIEVAKQKEWENNKVFEANP---IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKT--EINLNXXXXXXXXXXXXXXGFK-YQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQI--------KDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKIS--IRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
RKGTAKL+ ++ IE+ Q++WE K FE + + KNKYFVTFPYPYMNG LHLGH FSLSKCEF++GY+ LKG+ L+ FG HCTGMPIK+ ADKLKREME +G PP FP+ E + K EI + K G +QW IMR G+ND+EI +F ++W++Y+PPL I ++K++G+KVDWRRSFITTD NPFYDSFVRWQF+ LK+ KI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +PY + ++FLVAATLRPETM+GQTNCW+ P ++YVA ++ V I R+ARNM++Q T + G V ++ + LG++L+GCAL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRD+K+K+ R Y IED VLPFEP+ +I+IP YG A +E KI+SQND +KL+EAKEK Y GFY G +++ Y G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y D +WK L + TF +E RRNFEA L L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMAYYTVAH+LQGG L+GR G + GI MT + W+++ P+ L LRREF YWYPVD+RVSGKDLVPNHL+Y+L+NH A+WP+++ + WP+ +RANGHLLLN+EKMSKSTGNFLT+S+A+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ ++ N+RTGP +D VFA+ +N I +TE +Y++MMYK L+ GF EFQ+ +D+YRE + H DL+ F+E Q L+L+PICPH+ +Y W +L K +S+M SWP G VDE L +YL +H+ R + +++ + I++AKSYPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L L+ ++++ ++ E +D+K+ + CCP +P F + P V V++VNP +G S +++I GDS V RR+A K++ I+D + V+L + D R +P+ + + PI + F V+ + ++ + N + IG+
Sbjct: 4 RKGTAKLDYLRKIELDIQEKWEKEKTFERDAPTTVGESSNKNKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQSLKGRKCLFPFGLHCTGMPIKACADKLKREMELYGTPPQFPDDEEEEKEKPKASDEIIIKDKAKGKKSKAVAKAGSSSFQWDIMRSLGLNDKEIVRFANAEHWLEYFPPLAIKDLKKMGVKVDWRRSFITTDVNPFYDSFVRWQFVTLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKIVEPYTAKFKSKVFYSSGMKGKNLFLVAATLRPETMFGQTNCWVRPDMKYVAFETASGDVFISTRRSARNMSFQG-FTKENGVVPVIMEILGQDLLGCALSAPLTSYKIIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDIKKKQALREKYGIEDKMVLPFEPIPIIEIPGYGNLSAPLVCDELKIQSQNDKEKLVEAKEKVYLKGFYEGIMLVDGYKGQKVQDVKKPIQKMMVEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGDAEWKKQATEALKSLETFCEETRRNFEATLAWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAYYTVAHLLQGGVLNGR-GDSPLGIKPEQMTREVWDFIFFKTAPFPKTDIPK--EHLQKLRREFEYWYPVDVRVSGKDLVPNHLSYFLYNHVAVWPKDNKK-WPQAVRANGHLLLNSEKMSKSTGNFLTLSQAVEKFSADGMRLALADAGDTVEDANFVETMADAGILRLYTWVEWVKEMIANQNNLRTGPADTFNDRVFASEMNAGIIKTEQHYERMMYKEALKSGFFEFQAAKDKYRELAIEGMHRDLVFQFIERQTLLLAPICPHLCEYTW-GLLVKTTSLMKASWPAAGPVDEILVRSSQYLMETAHDLRLRLKAYMLPPKNKKGDTKPPVKPSHCNIYVAKSYPPWQHSALCLLGKHYRSNNGVLPDNKVIAGELGALPELKKYMKRVMPFVAMIKENLEKNGPRVLDLEL-EFDERTVLMENLVYLTNSLELE--QIDVLFATE-ADDKVKEDCCPGKPFSVF--------RSEPGV---------------CVSLVNPQPSNGLFSTKVDIRQGDSKDNVIRRLA-KVNRLIKDLSQVKLMRYEDPVLGPRRVPVLGQEEKGKLPISEKSVFHVNLEEKRVTLADNSLTVDIGD 1177
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Medaka
Match: lars1b (leucyl-tRNA synthetase 1 [Source:NCBI gene;Acc:101154887]) HSP 1 Score: 1051.2 bits (2717), Expect = 0.000e+0 Identity = 549/1148 (47.82%), Postives = 740/1148 (64.46%), Query Frame = 3
Query: 318 MNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKT--EINLNXXXXXXXXXXXXXXGFK-YQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNA--------AIIWIAKSYPPWQMSILDSL-IDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKIS--IRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVS--KSGISFSVNGVAHRIGE 3713
MNG LHLGH FSLSKCEF++GY+ LKG+ L+ FG HCTGMPIK+ ADKLKREME +G PP FP+ E + K EI + K G +QW IMR G+ND+EI +F ++W++Y+PPL I ++K++G+KVDWRRSFITTD NPFYDSFVRWQF+ LK+ KI FGKR TI+SP D QPCMDHDR +GEGVGPQEYTLIKMK+ +PY + ++FLVAATLRPETM+GQTNCW+ P ++YVA ++ V I R+ARNM++Q T + G V ++ + LG++L+GCAL APLT+YK IY LPM +IK++KGTG+VTSVPSD+PDD AALRD+K+K+ R Y IED VLPFEP+ +I+IP YG A +E KI+SQND +KL+EAKEK Y GFY G +++ Y G VQ K+ IQ ++ G A+ Y EPE+QV+SRS ECVVALCDQWYL+Y D +WK L + TF +E RRNFEA L L E+ACSR+YGLGTR+PWDEQ+L+ESLSDSTIYMAYYTVAH+LQGG L+GR G + GI MT + W+++ P+ L LRREF YWYPVD+RVSGKDLVPNHL+Y+L+NH A+WP+++ + WP+ +RANGHLLLN+EKMSKSTGNFLT+S+A+EK+SADGMR+A ADAGD++EDANFVE MADAG+LRLY+++EWVKE++ ++ N+RTGP +D VFA +D+YRE + H DL+ F+E Q L+L+PICPH+ +Y W +L K +S+M SWP G VDE L +YL +H+ R + +++ + I++AKSYPPWQ S L L G LPDNK + L PELKK MK+ M + I+ + V L+ E DE++V+ N Y+ +L L+ ++++ ++ E +D+K+ + CCP +P F + P V V++VNP +G S +++I GDS V RR+A K++ I+D + V+L + D R +P+ + + PI + F V+ + ++ + N + IG+
Sbjct: 1 MNGRLHLGHTFSLSKCEFAVGYQSLKGRKCLFPFGLHCTGMPIKACADKLKREMELYGTPPQFPDDEEEEKEKPKASDEIIIKDKAKGKKSKAVAKAGSSSFQWDIMRSLGLNDKEIVRFANAEHWLEYFPPLAIKDLKKMGVKVDWRRSFITTDVNPFYDSFVRWQFVTLKERKKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVGPQEYTLIKMKIVEPYTAKFKSKGKNLFLVAATLRPETMFGQTNCWVRPDMKYVAFETASGDVFISTRRSARNMSFQG-FTKENGVVPVIMEILGQDLLGCALSAPLTSYKIIYALPMLTIKEDKGTGVVTSVPSDAPDDIAALRDIKKKQALREKYGIEDKMVLPFEPIPIIEIPGYGNLSAPLVCDELKIQSQNDKEKLVEAKEKVYLKGFYEGIMLVDGYKGQKVQDVKKPIQKMMVEKGEAMIYMEPEKQVMSRSADECVVALCDQWYLDYGDAEWKKQATEALKSLETFCEETRRNFEATLAWLQEHACSRTYGLGTRLPWDEQWLIESLSDSTIYMAYYTVAHLLQGGVLNGR-GDSPLGIKPEQMTREVWDFIFFKTAPFPKTDIPK--EHLQKLRREFEYWYPVDVRVSGKDLVPNHLSYFLYNHVAVWPKDNKK-WPQAVRANGHLLLNSEKMSKSTGNFLTLSQAVEKFSADGMRLALADAGDTVEDANFVETMADAGILRLYTWVEWVKEMIANQNNLRTGPADTFNDRVFA--------------------------------AKDKYRELAIEGMHRDLVFQFIERQTLLLAPICPHLCEYTW-GLLVKTTSLMKASWPAAGPVDEILVRSSQYLMETAHDLRLRLKAYMLPPKNKKGDTKPPVKPSHCNIYVAKSYPPWQHSALCLLGKHYRSNNGVLPDNKVIAGELGALPELKKYMKRVMPFVAMIKENLEKNGPRVLDLEL-EFDERTVLMENLVYLTNSLELE--QIDVLFATE-ADDKVKEDCCPGKPFSVF--------RSEPGV---------------CVSLVNPQPSNGLFSTKVDIRQGDSKDNVIRRLA-KVNRLIKDLSQVKLMRYEDPVLGPRRVPVLGQEEKGKLPISEKSVFHVNLEEKRVTLADNSLTVDIGD 1082
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Match: SMESG000031601.1 (SMESG000031601.1) HSP 1 Score: 2402.86 bits (6226), Expect = 0.000e+0 Identity = 1180/1183 (99.75%), Postives = 1181/1183 (99.83%), Query Frame = 3
Query: 165 MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVSKSGISFSVNGVAHRIGE 3713
MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFG HCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLNKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYL+NHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPA EVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVSKSGISFSVNGVAHRIGE
Sbjct: 1 MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGLHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLNKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQYLVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLYNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAAEVPRVAMESNSLMRATVTVVNPDLFSGFVSHEIEILDGDSFVTVARRVADKISIRDSTAVELYHFIDEKASARLIPLSTEMMRDLQPIDRNATFSVSKSGISFSVNGVAHRIGE 1183
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Match: SMESG000029599.1 (SMESG000029599.1) HSP 1 Score: 2117.81 bits (5486), Expect = 0.000e+0 Identity = 1048/1100 (95.27%), Postives = 1059/1100 (96.27%), Query Frame = 3
Query: 162 HMNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQY--LVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGF 3455
H++RKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFG HCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEIN+NKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQ + + R+ W+ ++ + SDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYL+NHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPA EVPRVAMESNSLMRATVTVVNPDLFSG
Sbjct: 17 HVDRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGLHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEININKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQKTSMNTPAH----------------------ARMDWEREFPGMNNIWSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLYNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAAEVPRVAMESNSLMRATVTVVNPDLFSGL 1094
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Match: SMESG000029599.1 (SMESG000029599.1) HSP 1 Score: 2116.66 bits (5483), Expect = 0.000e+0 Identity = 1049/1099 (95.45%), Postives = 1058/1099 (96.27%), Query Frame = 3
Query: 165 MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEINLNXXXXXXXXXXXXXXGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQVNTFSDEVRRNFEANLENLHEYACSRSYGLGTRIPWDEQY--LVESLSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLFNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRXXXXXXXXXXXXXXHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAVEVPRVAMESNSLMRATVTVVNPDLFSGF 3455
MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFG HCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEIN+NKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQ + + R+ W+ ++ + SDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYL+NHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPA EVPRVAMESNSLMRATVTVVNPDLFSG
Sbjct: 1 MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGLHCTGMPIKSSADKLKREMESFGFPPVFPEIETPVAIEEKTEININKVKGKKSKAVAKSGGFKYQWQIMRHNGMNDEEIKKFTETDYWIKYYPPLTITNMKRLGIKVDWRRSFITTDANPFYDSFVRWQFLKLKKLNKIMFGKRQTIFSPIDNQPCMDHDRSSGEGVGPQEYTLIKMKLEKPYPQCLEQIKDDVFLVAATLRPETMYGQTNCWIHPTIEYVAVKSTKHGVLICVERAARNMAYQEILTDQPGEVIILSKFLGKELMGCALQAPLTTYKTIYTLPMFSIKQNKGTGIVTSVPSDSPDDYAALRDLKRKEDTRSLYKIEDYKVLPFEPVEVIDIPEYGRQCAVKCVEEFKIKSQNDADKLMEAKEKCYKLGFYSGKLIIGKYAGMPVQKAKEIIQSDLITSGLAINYSEPERQVISRSGGECVVALCDQWYLNYKDEQWKSITKSCLNQKTSMNTPAH----------------------ARMDWEREFPGMNNIWSDSTIYMAYYTVAHVLQGGSLDGRSGVNSSGITITDMTPDAWEYVLGDDRSVAGNLNPELVGKLDGLRREFHYWYPVDLRVSGKDLVPNHLTYYLYNHCAIWPENSDQYWPKNIRANGHLLLNNEKMSKSTGNFLTISEAIEKYSADGMRMAFADAGDSIEDANFVEDMADAGLLRLYSFIEWVKEIVESKPNMRTGPLSLHSDLVFANAINRTIEETETNYKQMMYKRVLQLGFHEFQSIRDRYRETCMGDYHADLITLFVEIQCLILSPICPHITDYIWTDILNKPSSIMNESWPIPGKVDEKLSTEERYLDGISHEFRKQSLQKPKSKSSEQHNAAIIWIAKSYPPWQMSILDSLIDMSDKEGKLPDNKSLNSRLSENPELKKRMKKAMDLIQSIRVKCNERSENVSRLKTPEIDEKSVIESNFRYMAKTLNLDLGKLELKYSDECSDEKLFDSCCPMEPKITFLVVKEDDKSAPPAAEVPRVAMESNSLMRATVTVVNPDLFSGL 1077
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Match: SMESG000031004.1 (SMESG000031004.1) HSP 1 Score: 51.6026 bits (122), Expect = 3.217e-6 Identity = 26/75 (34.67%), Postives = 39/75 (52.00%), Query Frame = 3
Query: 264 IYGKDKKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESF 488
++ K N YF+T P Y N H+GH ++ C+ + RLKGKN ++ G G+ I+ SA+ LK F
Sbjct: 13 LFNFKKLNSYFITSPIYYPNDKPHIGHLYTNCLCDVIARWNRLKGKNVIFSTGTDEHGIKIQKSAENLKMNYNKF 87
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Match: SMESG000031004.1 (SMESG000031004.1) HSP 1 Score: 51.2174 bits (121), Expect = 3.479e-6 Identity = 26/70 (37.14%), Postives = 37/70 (52.86%), Query Frame = 3
Query: 279 KKNKYFVTFPYPYMNGNLHLGHAFSLSKCEFSMGYERLKGKNALWGFGFHCTGMPIKSSADKLKREMESF 488
K N YF+T P Y N H+GH ++ C+ + RLKGKN ++ G G+ I+ SA+ LK F
Sbjct: 18 KLNSYFITSPIYYPNDKPHIGHLYTNCLCDVIARWNRLKGKNVIFSTGTDEHGIKIQKSAENLKMNYNKF 87 The following BLAST results are available for this feature:
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 4
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 3
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Leucine--tRNA ligase, cytoplasmic vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Leucine--tRNA ligase, cytoplasmic vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Leucine--tRNA ligase, cytoplasmic vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024910 ID=SMED30024910|Name=Leucine--tRNA ligase, cytoplasmic|organism=Schmidtea mediterranea sexual|type=transcript|length=3785bpback to top protein sequence of SMED30024910-orf-1 >SMED30024910-orf-1 ID=SMED30024910-orf-1|Name=SMED30024910-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1193bp MNRKGTAKLNTIKDIEVAKQKEWENNKVFEANPIYGKDKKNKYFVTFPYPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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