Protocadherin
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024873 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 5
Homology
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 251.136 bits (640), Expect = 9.774e-69 Identity = 200/679 (29.46%), Postives = 319/679 (46.98%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN-NNLNEPIVD------VSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSD-LIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA-----LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P++ P I L+I EN IG+LF IP A D D + F L + D E + P+L + ++DRE D +L I + D GSPP ++ + +LD NDN P F Y L EN + + I V A D D G ++ Y + + V+R ++ G I + +D + + L +S V+A D G S+ V++ + D+ND P I + + + +T + N++E + + V V D D+G N C + G F L + SD Y L D EK I D G P L+S+ + V +VDVNDN P F+ T + E++ G V+ ++ A D D G N++L+Y + +F + G + V LDR E + + VV +D G P+L + +N++D N+ P F S ++F+V E+ +P +G + V D DKG NAQ+ L+++ + F I + G + S DRE++ Y L A+DG V R G V I + D NDN+P P+ S+K + + ED DSG NA + SI G F I ++ L ++++ H G+H+L+V DRG+PP+ + + + ++++
Sbjct: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQ-VAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSV-IQVKANDSDQGANAEIEYTFHQA-PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS--VLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF--TISPETGEIQVKTSLDREQR-ESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMEN-------MPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG--GVPPRSAYVG-VTINVLDENDNAPYIT----APSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET 815 HSP 2 Score: 145.976 bits (367), Expect = 6.530e-35 Identity = 162/637 (25.43%), Postives = 270/637 (42.39%), Query Frame = 2
Query: 629 IELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVS--NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD---------PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINK---FQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL--SPKNMVH 2389
+E + +TD +GSP L EG I +Q D+NDN P F++ +++ EN + SL PI + A D D+G G SY+ + A + + +LI + D SY + D G P +SS + + ++D ND P + + + EN+ + ++ V +D DQG N + H+ +++ + D + + DRE + ++ D G ++ + V + D+NDN PT + +I E T V V+ D+DEG N+ + ++ T + + +++ L + D +++ +V D G P LS+ + + ++D+N+ PVF QS PE+ KP I I SD D G NA+L +++ F IS G +Q LDRE++E Y+L ++A D G+P +Q T +V++ + D NDN P F + Y V + AL V D D G NA V LS++ G I S DR++QS + + D G PP+S+ + + I + +D+ P +P N H
Sbjct: 134 LEFEVSITDLVQNGSPRLL-EGQIEVQ--DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP--KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-------YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPEN--------NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQ----GTATVLVNVLDCNDNDPKFMLS-------GYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQST-------------YTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSH 723
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH7 (protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659]) HSP 1 Score: 250.366 bits (638), Expect = 1.824e-68 Identity = 211/693 (30.45%), Postives = 325/693 (46.90%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITID---------DSQPLS----PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + ++ DSQ P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRAADLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGIFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNK 909
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH7 (protocadherin 7 [Source:HGNC Symbol;Acc:HGNC:8659]) HSP 1 Score: 250.366 bits (638), Expect = 1.884e-68 Identity = 211/693 (30.45%), Postives = 325/693 (46.90%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITID---------DSQPLS----PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + ++ DSQ P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRAADLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGIFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNK 909
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH1 (protocadherin 1 [Source:HGNC Symbol;Acc:HGNC:8655]) HSP 1 Score: 251.136 bits (640), Expect = 2.086e-68 Identity = 200/679 (29.46%), Postives = 318/679 (46.83%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN-NNLNEPIVD------VSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSD-LIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA-----LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P++ P I L+I EN IG+LF IP A D D + F L D E + P+L + ++DRE D +L I + D GSPP ++ + +LD NDN P F Y L EN + + I V A D D G ++ Y + + V+R ++ G I + +D + + L +S V+A D G S+ V++ + D+ND P I + + + +T + N++E + + V V D D+G N C + G F L + SD Y L D EK I D G P L+S+ + V +VDVNDN P F+ T + E++ G V+ ++ A D D G N++L+Y + +F + G + V LDR E + + VV +D G P+L + +N++D N+ P F S ++F+V E+ +P +G + V D DKG NAQ+ L+++ + F I + G + S DRE++ Y L A+DG V R G V I + D NDN+P P+ S+K + + ED DSG NA + SI G F I ++ L ++++ H G+H+L+V DRG+PP+ + + + ++++
Sbjct: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVA-EDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSV-IQVKANDSDQGANAEIEYTFHQA-PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS--VLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF--TISPETGEIQVKTSLDREQR-ESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMEN-------MPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG--GVPPRSAYVG-VTINVLDENDNAPYIT----APSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET 815 HSP 2 Score: 146.362 bits (368), Expect = 7.092e-35 Identity = 162/637 (25.43%), Postives = 270/637 (42.39%), Query Frame = 2
Query: 629 IELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSY--KHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD---------PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINK---FQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL--SPKNMVH 2389
+E + +TD +GSP L EG I +Q D+NDN P F++ +++ EN + SL PI + A D D+G G SY + + A + + +LI + D SY + D G P +SS + + ++D ND P + + + EN+ + ++ V +D DQG N + H+ +++ + D + + DRE + ++ D G ++ + V + D+NDN PT + +I E T V V+ D+DEG N+ + ++ T + + +++ L + D +++ +V D G P LS+ + + ++D+N+ PVF QS PE+ KP I I SD D G NA+L +++ F IS G +Q LDRE++E Y+L ++A D G+P +Q T +V++ + D NDN P F + Y V + AL V D D G NA V LS++ G I S DR++QS + + D G PP+S+ + + I + +D+ P +P N H
Sbjct: 134 LEFEVSITDLVQNGSPRLL-EGQIEVQ--DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP--KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-------YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPEN--------NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQ----GTATVLVNVLDCNDNDPKFMLS-------GYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQST-------------YTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSH 723
BLAST of Protocadherin vs. Ensembl Human
Match: PCDH9 (protocadherin 9 [Source:HGNC Symbol;Acc:HGNC:8661]) HSP 1 Score: 241.506 bits (615), Expect = 1.074e-65 Identity = 204/658 (31.00%), Postives = 320/658 (48.63%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDI--TIF--ENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPF-LIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYK----EYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRP 2314
D NDNAP +P P I +SI EN I + F IP A D D T N Y++ S F L + T + ++P+L ++ ++DRE D + I + D G+P + I+ + + DVNDN P F + + + EN + + + I + A D D G+ ++ Y + KR FA+N+T G I + +SLD + E + V V G + + TV IN+ DVND P I L + I T++ E + +N I ++V D D +NG+ CF+ F L K + + + + ++ KE F++ I D G PSL + L+ V + D NDN P F+ P S+ E++ G +T + A D+D G N+ ++Y + N F F L G L ++ DR + E F V D+G P L +Q + + ++D N+ P F + F F V E+ +PK +G I V+D D G N +TL+I DN N ++G+++S DRE++ Y + A DG Q + T V I + D+NDNSP+ P+ S+K + ++A +F D D+G NA + +I G F ID ++ L K G+H+L+V D G P
Sbjct: 134 DTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPD-TGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSV-IQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDRE---ETAIHKVTVLASDGS-STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHL--KAVYDNQYLLETSSLLDYEGTKE-FSF-KIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLG----PNASF--FDLDRKTGVLTASRVFDR-EEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSEN-------LPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG---QPPRSSTAKVTINVMDVNDNSPVV---ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 162.925 bits (411), Expect = 3.259e-40 Identity = 171/587 (29.13%), Postives = 264/587 (44.97%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK---GFDLLFK-QNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSM-----PATSFSIL-EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHL---DRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI----KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I I + D NDN P F + IS+ EN +NS PI SA D D+G G Y+ + N SV + + GE +LI + D + +Y + D G P SS+ + + + DVND P+ + ++ I EN + ++ + D D G N + ++ G + LF N + LI Q DRE+ A T+ D S + +T+ + DVNDN P + P L E P+ T + + DKD +N ++I I + PF +++ + NQ+L LLD E FS +V SD G+P+L+ + + L D N+ PP+FNQ +V E+ L L I+ +D D G NA + + N + F + G+L + V DREE+E + T+ A D GTP +Q + +V++ + D NDNSP F H +F + +Y +I V D D+G N V LSI ++ PY + +K N E Q + V D G+PP+SS+ ++ I + D SP
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPI-PSATDPDTGFNGVQHYE--LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPV--FKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIR-YIFGAQVAPATKRLFALNNTTGLITVQ----RSLDREETAIHKVTVLASDGS--STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI-------EREVPFHLKA---VYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLT-------TISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQ----AAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVIT--VTDADAGENKAVTLSILNDNDNFVLDPYSGV------IKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673 HSP 3 Score: 134.806 bits (338), Expect = 1.760e-31 Identity = 157/551 (28.49%), Postives = 243/551 (44.10%), Query Frame = 2
Query: 794 INVSAVDCDSGNFGKLSYKHSVSNTDS--VKRHFAINSTNGEI----------RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING-QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQL--IYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGR-PALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLV-PKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN---KFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE--LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+N+S ++ +G L Y+ D+ VK ++S+ GEI +L Y NE + VV + L + I + D ND P+ + +I+I EN +N S D D G NG Q L G F L + QL+ + DRE++ I D G P +S+ ++ V + DVNDN P F I E++P+GT V ++ A D D G N+++ I+ T ++F L + G + V + LDR + I V V+ SD PA + +TIN+ D+N+ PP N + P + + +L P I I VSD D VN ++ I+ + K + +L++ ++LD E +E+ ++A D G P + T V + L D NDN PIF N P+ ++S E R L + D+DSG NA D+ + G A +F +DR + +R E Q V +D G PP S + +T+ D SPK
Sbjct: 47 LNISHINAATGTSASLVYRLVSKAGDAPLVK----VSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRL---IKIKIIVKDTNDNAPMFP--SPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFA--LNNTTGLITVQRSLDR-EETAIHKVTVLASDGSSTPA---RATVTINVTDVNDNPP--NIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLN----QTALVRVKLEDENDNPPIF--NQPV-IELSVSENNRRGLYLTTISATDEDSGKNA--DIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPK 571
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 197.593 bits (501), Expect = 3.685e-51 Identity = 172/612 (28.10%), Postives = 294/612 (48.04%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGY----IAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDLSIKPGIIAP---YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
++ + +DRET I L ++ +D G+P ++ I ++DVNDN P F++ Y +++ EN + +++ V A D D G GK+ Y + S S I+ + GE+ L + +D + V+ A D QPALSS+ + IN++D+ND P +L + K IT+ EN + E + V D D G NG + G + D + ++ + +L+ DRE A +T D G PSL +S I V++ D+NDN PTF + +I E P G+ + ++A+D DE + ++ Y I + ++F I G +L V+ L R + V V +S + L + + + + D+N+ P FN F +PE H P IGY + D D+G NA++ +I D+ F+I +G + + LDRE++ + + + A D +P + + + + L+D+NDNSP F T SY + ++ + + D D G N +VD + +P F +DR +++++ KL E + L + +DRG P S++ EI +T+ D +P
Sbjct: 327 IQTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIA-TVKATDEDFGTNGKVHYSMASS---SGIGGLTIDYSTGEVTLRERID---AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAP--TLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSE--DFIIDEDSGLIKTTKLL-----DRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEE--ADREVFSILDIGDQGAILSVSGELKR----QDHKVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPE----HSP-------IGYPVITLKAEDHDRGDNARIVYSI-DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLN----TSTQIEVILDDINDNSPQF-------TSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAP 890 HSP 2 Score: 179.489 bits (454), Expect = 2.066e-45 Identity = 156/603 (25.87%), Postives = 282/603 (46.77%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAV--SDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+++L S+DRE D+ L + + P ++ + + +LDV DN P F Y +RE+ + + + ++V A D DSG G++ Y N K AIN+ +G I+ LD ++ + + V+A D G P S+ V I +VDVND P+ + + ++TI EN + I V D D G NG+ + + G L D ++ + + D K + I D P+L+S+ +T+ ++D+ND+ PT ++ E+ IG V +V A+D+D G N + Y + F+I+ + L+ +LLD E +S+ V D G P+L+ I + L DIN+ P F++ ++ T+ E+ +P+ I + +D D+ + ++ A ++ + I G + SV+ + + + ++ + A D +Q R V +F++D+N ++P F+ + P K+ + + +I L ED D G NA + SI + +F ID + ++ L E + +IV D PP ++S +I++ +DD SP+
Sbjct: 221 EIRLAKSMDREVLDKHILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIREDAPIGTTV-LSVFARDLDSGENGEIEYSLGEGNG---KNLLAINAKSGVIQTAAPLDRETLSLIRLD--VIASDKGTPKRESTAMVEITVVDVNDNAPVFASDS--YNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGL----TIDYSTGEVTLRERID-AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED-------FIIDEDSGLI---KTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEE-------MPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRVEISATD-QGGLQGRCVVN----VFIDDVN-SAPYFN-DHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDS---SQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQ 783 HSP 3 Score: 165.236 bits (417), Expect = 4.892e-41 Identity = 185/650 (28.46%), Postives = 288/650 (44.31%), Query Frame = 2
Query: 377 DLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSV--HDLDQGINGQ--------FNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN-----INKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE------LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKL 2254
D+NDNAP + ++I EN I + A D D +S + L D + ++ L+ ID + N I VI D P L+ +TI ++D+ND+ PT + +I+L EN + + V A+D DSG G + Y S F I+ +G I+ K LD ++ YS V A D G P+L++STT+ + + D+ND P + +K ++TI E I+ + +D DQ I + F+ IG +G L L HK E I+ D G L ++ V I DVN + P F+ S I EHSPIG V ++A D D G N++++Y I ++Q F + S+G++ V+ LDR D FSVIV SDH P L+ +I + L DIN+ P F S++ T+ ED +P + ++ D D G N + + ++ I F++ +G L+ + LDRE+ L + A D GTP + + + + L+D+NDN+P F ++SY Y+ + + D D G NA + I G A F I+ D + + R L
Sbjct: 367 DVNDNAPVFASDSYNVTILENITIPAVIATVKATDED----FGTNGKVHYSMASSSGIGGLTID--YSTGEVTLRERIDAK-NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVG-RVYAIDEDSGPNGIIKYSMEGS------EDFIIDEDSGLIKTTKLLDRET--TARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAP--TFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELK-------RQDHKVRVE--------ISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID----SSQFFR--IDPSSGDISVSSDLDRE-DRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISED-------IPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSL----SAASEITLTLSDVNDNAPTFE-------QLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRIL 955 HSP 4 Score: 154.836 bits (390), Expect = 7.823e-38 Identity = 129/527 (24.48%), Postives = 243/527 (46.11%), Query Frame = 2
Query: 731 FSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRN---------FPLPTKVSYKEYV---RHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQG 2272
F KY+ L E+ + ++ +++V + L Y + F +++ +GEIRL KS+D + ++ + V A++ P +S+STTV+++++DV D PI + +I E+ + ++ V DLD G NG+ L G +LL S +I DRE + + D G P S+ ++ + +VDVNDN P F+ + + +ILE+ I V+ V+A D+D G N ++ Y ++ + + S G + + + +D + ++ D +PALS+ + +TIN+IDIN+ P + T+ E+ V +G + D D G N + +++ + + +G++++ +LDRE Y L + A D GTP + T + + L D+NDN+P F + P +++ + V + I +E+ D +++D+ + I++ S + RQ K+ ++ + QG
Sbjct: 165 FQQEKYVKELPEDTPIETI----IASVKASHASSQPLYYSMVAPQDSRSQNLFTLDTMSGEIRLAKSMDREVLDK--HILKVTAYERVDPTISASTTVVVHVLDVQDNSPIFEKDSYFGEIR--EDAPIGTTVLSVFARDLDSGENGEIEYSLGEGNGKNLLAINAKSGVI----QTAAPLDRETLSLIRLDVIASDKGTPKRESTAMVEITVVDVNDNAPVFASDSYNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGLTIDY---STGEVTLRERID--AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEEN-------VAIGEEVGRVYAIDEDSGPNGIIKYSMEGSEDFIIDEDSGLIKTTKLLDRETTARYSLKVTARDMGTPSLNTSTT----IAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILS--VSGELKRQDHKVRVEISATDQG 661 HSP 5 Score: 116.316 bits (290), Expect = 7.177e-26 Identity = 139/504 (27.58%), Postives = 225/504 (44.64%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFD--LLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNG--NLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN 1873
D+NDNAP + K ++ISE G+ AVD D +K + ++ F D Q L + + R+ + ++ + I TD G L G ++ + I DVN + P F+ H + + + E+ + + I + A D D G+ ++ Y + DS + F I+ ++G+I + S D D + ++S +V A DH P L++ST + + + D+ND P S TI E+ + + VS D D G NG + FL LF+ D L K DRE+ A I D G PSL+++ IT+ + DVNDN PTF + I E+SP+G+ V + A D DEG N+ + + I E NG +L D F + S LS+ + + I++ D+N+ P F + + D++ + R IG+I D D+ NA L +++N
Sbjct: 573 DINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADRE------VFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPV-ITLKAEDHDRGDNARIVY-----SIDS-SQFFRIDPSSGDISV--SSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSP--QFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRL---DRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG---QLSSTVPVRIHVSDVNDNKPALKD----FVILMNRFDNVQMA---RQIGFIPAFDPDQ--NATLEYFLEEN 1040
BLAST of Protocadherin vs. Ensembl Celegans
Match: fmi-1 (FlaMIngo (Cadherin plus 7TM domain) homolog [Source:UniProtKB/TrEMBL;Acc:A0A0K3AUS4]) HSP 1 Score: 180.644 bits (457), Expect = 7.578e-46 Identity = 163/573 (28.45%), Postives = 277/573 (48.34%), Query Frame = 2
Query: 686 IITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGY----IAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAP---YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
++ I ++DVNDN P F++ Y +++ EN + +++ V A D D G GK+ Y + S S I+ + GE+ L + +D + + V+ A D QPALSS+ + IN++D+ND P +L + K IT+ EN + E + V D D G NG + G + D + ++ + +L+ DRE A +T D G PSL +S I V++ D+NDN PTF + +I E P G+ + ++A+D DE + ++ Y I + ++F I G +L V+ L R + V V +S + L + + + + D+N+ P FN F +PE H P IGY + D D+G NA++ +I D+ F+I +G + + LDRE++ + + + A D +P + + + + L+D+NDNSP F + T +S V + + D D G N +VD + +P F +DR +++++ KL E + L + +DRG P S++ EI +T+ D +P
Sbjct: 1 MVEITVVDVNDNAPVFASDSYNVTILENITIPAVIA-TVKATDEDFGTNGKVHYSMASS---SGIGGLTIDYSTGEVTLRERIDAKNS---PITAVIRAKDGAQPALSSTVPLTINVIDINDHAP--TLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSE--DFIIDEDSGLIKTTKLL-----DRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDE--DQKITYRIEE--ADREVFSILDIGDQGAILSVSGELKR----QDHKVRVEISATDQGGLQGRCVVNVFIDDVNS-APYFNDHPFSVKIPE----HSP-------IGYPVITLKAEDHDRGDNARIVYSI-DSSQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLN----TSTQIEVILDDINDNSPQFTSSSYAAT-ISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAP 531 HSP 2 Score: 164.851 bits (416), Expect = 5.714e-41 Identity = 185/650 (28.46%), Postives = 288/650 (44.31%), Query Frame = 2
Query: 377 DLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSV--HDLDQGINGQ--------FNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD-----NINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE------LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKL 2254
D+NDNAP + ++I EN I + A D D +S + L D + ++ L+ ID + N I VI D P L+ +TI ++D+ND+ PT + +I+L EN + + V A+D DSG G + Y S F I+ +G I+ K LD ++ YS V A D G P+L++STT+ + + D+ND P + +K ++TI E I+ + +D DQ I + F+ IG +G L L HK E I+ D G L ++ V I DVN + P F+ S I EHSPIG V ++A D D G N++++Y I ++Q F + S+G++ V+ LDR D FSVIV SDH P L+ +I + L DIN+ P F S++ T+ ED +P + ++ D D G N + + + +I F++ +G L+ + LDRE+ L + A D GTP + + + + L+D+NDN+P F ++SY Y+ + + D D G NA + I G A F I+ D + + R L
Sbjct: 8 DVNDNAPVFASDSYNVTILENITIPAVIATVKATDED----FGTNGKVHYSMASSSGIGGLTID--YSTGEVTLRERIDAK-NSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVG-RVYAIDEDSGPNGIIKYSMEGS------EDFIIDEDSGLIKTTKLLDRET--TARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAP--TFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELK-------RQDHKVRVE--------ISATDQG--GLQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSID----SSQFFR--IDPSSGDISVSSDLDR-EDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISED-------IPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSL----SAASEITLTLSDVNDNAPTFE-------QLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRIL 596 HSP 3 Score: 140.584 bits (353), Expect = 2.265e-33 Identity = 145/507 (28.60%), Postives = 230/507 (45.36%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTD-----SVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVV---VSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK--FQI----SHNGMLQ--SVAVLDREEKE-EYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSP 2056
+K +DRET R L + D G+P L I + + D+NDN PTF +Y +++ E S + I + AVD D K++Y+ ++ + + AI S +GE +K D+ E+S A D G L V + I DVN P N + I E++ + P++ + D D+G N + + + F + D + DRE A +T D+ P L +S I VI+ D+NDN P F+ + + +I E P+GT +V A+D D G N + Y +++ ++ + L ++G L V+ LDR E F+VIV+ D G P+LS EIT+ L D+N+ P F Q ++ + E+ P +G I D D+G NA ++ I + F I NG+++ + A D E K ++ L A G Q+ TV V I ++D+NDN P
Sbjct: 174 IKTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEEMPRGSQI-ITLKAVDNDEDQ--KITYRIEEADREVFSILDIGDQGAILSVSGE---LKRQDHKVRVEIS------ATDQG--GLQGRCVVNVFIDDVN-SAPY--FNDHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDSSQFFRI-------DPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRLDRTSGTLRVSSKLDR----EQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENS-------PVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG----QLSSTV--PVRIHVSDVNDNKP 639 HSP 4 Score: 124.02 bits (310), Expect = 2.492e-28 Identity = 115/457 (25.16%), Postives = 211/457 (46.17%), Query Frame = 2
Query: 1022 VIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAV--SDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
V I +VDVND P+ + + ++TI EN + I V D D G NG+ + + G L D ++ + + D K + I D P+L+S+ +T+ ++D+ND+ PT ++ E+ IG V +V A+D+D G N + Y + F+I+ + L+ +LLD E +S+ V D G P+L+ I + L DIN+ P F++ ++ T+ E+ +P+ I + +D D+ + ++ A ++ + I G + SV+ + + + ++ + A D +Q R V +F++D+N ++P F+ + P K+ + + +I L ED D G NA + SI + +F ID + ++ L E + +IV D PP ++S +I++ +DD SP+
Sbjct: 2 VEITVVDVNDNAPVFASDS--YNVTILENITIPAVIATVKATDEDFGTNGKVHYSMASSSGIGGL----TIDYSTGEVTLRERID-AKNSPITAVIRAKDGAQPALSSTVPLTINVIDINDHAPTLIAAQKMITLEENVAIGEEVGRVYAIDEDSGPNGIIKYSMEGSED-------FIIDEDSGLI---KTTKLLDRETTARYSLKVTARDMGTPSLNTSTTIAVVLKDINDNAPTFDKKEYNVTISEE-------MPRGSQIITLKAVDNDEDQKITYRIEEADREVFSILDIGDQGAILSVSGELKRQDHKVRVEISATD-QGGLQGRCVVN----VFIDDVN-SAPYFN-DHPFSVKIPEHSPIGYPVITLKAEDHDRGDNARIVYSIDS---SQFFRIDPSSGDISVSSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSPQ 424 HSP 5 Score: 115.546 bits (288), Expect = 1.038e-25 Identity = 139/504 (27.58%), Postives = 225/504 (44.64%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFD--LLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNG--NLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN 1873
D+NDNAP + K ++ISE G+ AVD D +K + ++ F D Q L + + R+ + ++ + I TD G L G ++ + I DVN + P F+ H + + + E+ + + I + A D D G+ ++ Y + DS + F I+ ++G+I + S D D + ++S +V A DH P L++ST + + + D+ND P S TI E+ + + VS D D G NG + FL LF+ D L K DRE+ A I D G PSL+++ IT+ + DVNDN PTF + I E+SP+G+ V + A D DEG N+ + + I E NG +L D F + S LS+ + + I++ D+N+ P F + + D++ + R IG+I D D+ NA L +++N
Sbjct: 214 DINDNAPTFDKKEYNVTISEEMPRGSQIITLKAVDNDEDQKITYRIEEADRE------VFSILDIGDQGAILSVSGELKRQ-DHKVRVEISATDQGG--LQGRCVVNVFIDDVN-SAPYFNDHPFSVKIPEHSPIGYPV-ITLKAEDHDRGDNARIVY-----SIDS-SQFFRIDPSSGDISV--SSDLDREDRATFSVIVTASDHASPPLNTSTQIEVILDDINDNSP--QFTSSSYAATISEDIPVGTSFLQVSAIDADIGPNGIVDYFLNESSSSPSIQLFRL---DRTSGTLRVSSKLDREQFAVIVLPIFARDRGTPSLSAASEITLTLSDVNDNAPTFEQLSYDLYIAENSPVGSTVGTIVARDADEGDNADISFRIFGGADAKLFDIEEDAEQNGVVRILTRAEFDYEAKANKFFFELQASSG---QLSSTVPVRIHVSDVNDNKPALKD----FVILMNRFDNVQMA---RQIGFIPAFDPDQ--NATLEYFLEEN 681
BLAST of Protocadherin vs. Ensembl Celegans
Match: cdh-1 (CaDHerin family [Source:UniProtKB/TrEMBL;Acc:Q5F4W0]) HSP 1 Score: 159.458 bits (402), Expect = 2.933e-39 Identity = 197/707 (27.86%), Postives = 305/707 (43.14%), Query Frame = 2
Query: 377 DLNDNAPHWP-KPIELSISENAFIGTLFNIPPAVDLDR-XXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELP---IISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAV---LDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE--LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLAL 2467
D NDNAP + + ++L ISE A +GT F +P D D + ++ F LA +++ Q L + +DRE D+ EL+I D G P G+ +I+I+D NDN P FS +Y S+ N + S L I V A D D G ++SY ++ S +FAI S +G I SL S ++ +VVA DHG P+LSSS V I ++ P II L +S + EN+ L + VS+ Q+ + G L Q +Y L+ DRE + + G + QL+T I D+NDN P + S+ +T A D D G N + Y + D + + + G + V +D + EI V D G PALS +++ +L+D + PP F ++ + +PED LV N S C + +L +D ++ + M +V + D E+++ Y+ T+IA + + T T + I L D+NDN PIF +P ++ +E + E L+ + D DSG V I + FSI+ V + L +G L+V KD G +S I IT+ D +P+ F+ SK +I ++ I SV A+
Sbjct: 114 DENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQ-ADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHL-ITVQATDADIGENSRISYDIKKTSAPS-NSNFAI-SQSGVITTTASLLPAS----THDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVES-NSAHLMENSTLGSIVARVSIAQ-------QYRDTKLRLIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQLLT--IGDINDNAPQWHSSQIHISLNRTQGGSRTLT---AKDPDLGQNGWIRYSVLDTELVS------IDKETGRIFVPNTIDCNIGSEI-KFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVAN-----NSQCGNSKRIRYSLQNQDE----HLTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANSE-----TSTSLISIRLKDVNDNWPIF---YPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSE--SSSFSINPVTGEVFAQKPLA---RGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQ----FSRSKYEIRTTEDILPGIAIGSVGAM 766 HSP 2 Score: 124.405 bits (311), Expect = 2.119e-28 Identity = 160/671 (23.85%), Postives = 285/671 (42.47%), Query Frame = 2
Query: 377 DLNDNAPHWPKPIELSISENAFIG---TLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN-------INKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D+NDNAP W ++ IS N G TL P DL + + S D + D E ++ + ++ID I+ + D GSP L+ + + +LD P F + + + E+ + + L + V A + GN ++ Y S+ N D H +++ +G + + K+ D++ + SY V+A + + +S++ + I + DVND PI N+ +T+ E EP++ VS D+D G G+ + ++ ++ + +A+ +F + ++ D G S +S I + ++D + P FS E G + V A+ S++ Y I + +Q + E G + V ++LD + + I G SNQ ++ I + D N+ PP F+ S ++ ED H P + SD DK N ++ +I + I++F G L + ++LD E YKL + A D G P T+ I + D+NDN+P F +++ +V + + + DKDS N + I G + YF ID +V R + E + ++ +D+G PP+SS+ +I++ D
Sbjct: 433 DINDNAPQWHSS-QIHISLNRTQGGSRTLTAKDP--DLGQNGWIRY---------SVLDTELVSIDKETG--RIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCL-VKVVANNSQCGNSKRIRY--SLQNQD---EHLTVDTMSGTVCIQKTFDFE--KQKSYQTTVIATNAN--SETSTSLISIRLKDVNDNWPIFYPNE--YHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHILSESS-SFSINPVTGEVFAQKPLARGRF--------HLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM-------SKVKYSI---YSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQATLPSGE---SNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFY-------VVQASDKDKKKNGEVRYSIISSHPGSSIEIDQF----TGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTL----FIHVLDVNDNAPEFEKSW-YTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNG--SEYFGIDEKLGNVYTKRSIDREVISHVDISIVAEDKGVPPRSSTASARISVLD 1037 HSP 3 Score: 120.553 bits (301), Expect = 3.277e-27 Identity = 127/456 (27.85%), Postives = 202/456 (44.30%), Query Frame = 2
Query: 626 RIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLP-INVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG-HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTP 1984
R LV+ D G I I ++D + P FS KY I E+ +LP I + +V G K+ Y + D +F+I+ G+I + + LD D + + + + G+ S+ T V+I I D ND P S SL +I+I E+ L+EP V D D+ NG+ +I H G + Q QL D E + D GIP +S+ + + ++DVNDN P F + +LE+SP T+V KV A DKD N Q++Y I++ ++ F + E GN+ + +DR + + + +V D G P S+ I+++D+N+ PP S T P+ P IG I D DKG+N + + + F + NG + L+ ++ +L++I D G P
Sbjct: 706 RFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTED-----ILPGIAIGSV----GAMSKVKYSIYSGDQD---HNFSIDEDTGKIYVTRYLDADVHDTVLLN-IQATLPSGE---SNQTQVVIFIEDHNDNPPQFS--SSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSIISSHPGSSIEIDQ-----FTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITN---GSEYFG--IDEKLGNVYTKRSIDREVISHV-DISIVAEDKGVPPRSSTASARISVLDVNDNPP----SCLSITPIVVPAGS----PLSTAIGTIVAMDPDKGLNGSVLYRAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGVP 1124 HSP 4 Score: 75.0998 bits (183), Expect = 2.713e-13 Identity = 181/798 (22.68%), Postives = 312/798 (39.10%), Query Frame = 2
Query: 110 SVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTLE-YCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPK----------LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSST--TVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQ---GINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDRE--KEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLD---GEIFSVIVVVSDHGRPALS--NQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRN---FPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQS----------VKLNRKLKSEHQ-GIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVH 2389
+++E P F+ L+ LA S N + S F + S G+I +LD + LE Y + + I +++ +N+LNDN P +P + EN +G+ A D+D + FL +D Q P + L + +D E L I TD T +TI + D+NDN PTFS Y ++ + A D D+ G L+Y + S+ F + +G + +K L +G Y V A D+G P+ S+S +VII + D+ K+ + EN+ + I ++S + + I + F LF ++ I + A H+F E E + C + VI++D NDNLP F+ A S+ + G + ++ A D+D G N ++ Y I + N + L G++ +N+ D LD + ++V DHG PA + ++++++ + + P F + V ED S ++ K R + + N L ++K++ K I G L LD E + + L DG R V + I + +++ +P+F ++ +P E V ++ A+ D+D G + VV SI DRQS ++L + L S I ++ V+ +++ ++I D QP PK ++H
Sbjct: 1840 TIDEGLPRGQFIAKLQPELAGLTYSIVEGN---IDSAFSVDSEGVIRTNLELDRE--------ILERYSLKVIGTGSGQQIGTRVDVRVNNLNDNVPSFPMSKPRRVPENLRVGSYVATVGAKDVDNLAPLRY---------------FLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDGSFDTFTN---LTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLG-QGSSSI---FRVAPESGAL-FMKVLP-PAGER--YLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKP---GFEKAEFRFEVMENSKIGLQIGNLSGEESREFHYRIQDPEASKIFSIDKFGRLF---VAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCH------------VIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRI---LSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVGT-VLQKIRASNRLGMR------NDGLLYSLKEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGNG----RSAVV-PLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESV-GQMQAI---DEDGGVHGVVKYSIS------------DRQSTVKIEEHTGIIRLQKPLVSRRNLTIEQITVVAYSSPTKQSKTTVYLEIGPFDVQPSLPKLLLH 2549 HSP 5 Score: 72.7886 bits (177), Expect = 1.497e-12 Identity = 84/300 (28.00%), Postives = 137/300 (45.67%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTD--DEHQFP-KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING--------QFNCFLIGHKGFDLLFKQ-NLSD 1237
D NDN P + +E+SI E+ + F + A D D+ K + Y ++ P + QF +L S +D E +L + TD G PP + + I +LDVNDN P F Y + + EN +++ V A D DS G++ Y+ ++N +F I+ G + +S+D + + + S +VA D G P SS+ + I+++DVND P S+ I + + L+ I + D D+G+NG Q + F++ G L +Q N SD
Sbjct: 829 DHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVR---------YSIISSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVG-KVVARDKDSLENGQIVYR--ITNG---SEYFGIDEKLGNVYTKRSIDREVISHVDIS--IVAEDKGVPPRSSTASARISVLDVNDNPPSC---LSITPIVVPAGSPLSTAIGTIVAMDPDKGLNGSVLYRAQLQSSLFVVKSNGDVYLRRQLNASD 1108 HSP 6 Score: 72.7886 bits (177), Expect = 1.497e-12 Identity = 171/771 (22.18%), Postives = 315/771 (40.86%), Query Frame = 2
Query: 134 NYFVTDLKNILAIPLNSSTRFNMLHVHSYFRL-SSSGIISVARQLDCDNDSNLCDKTLEYCMTKLFXXXXXXXXX-XXXXXXXDLNDNAPHW--PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENF--QLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG--------HKGFDLLFKQ-NLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMP--ATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLL--DGEIFSVIVVVSDHGRPALSNQIEITINLIDINNC-PPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD-NINK-FQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY----KEYVRH--ELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNR----KLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI 2350
N + D K ILA + +RF F + S++G ISV L D ++ + E+ + + + + + + D NDN P P EL I+E++ +G + + A D+D + K ++ S DL +P + +L S +I+L ++ D G P G+ + L++++ P + L++ + ++ LP L+Y N DS F+++S G IR +L+ D YS V+ GQ T V + + ++ND +P ++K + + EN + + V D+D FL+ H D +L+ + ++++ +H TI D + T+ +T+ + D+NDN PTFS P T+ S SP G K+ A D D L Y + ++ P +G L + ++L GE + V V +D+G P+ S + +++ + + P F ++ F F V E+ L IG ++ + + + I+D +K F I G L +DRE++ ++ + ID ++ V + + D NDN P+F T V+Y K+ + H ++ + D+DSG N V I G +++ D S++LN +L +++V +D G P +++ ++Q+++
Sbjct: 1644 NVGIEDFKRILATGMTEESRFRFQGNAPKFSINSTTGSISV---LPLDREA-----SQEHLLIIILTDGGSRNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDL--VPETGDLVLRRLSSLQSW------KIKLRVV--DHGVP-----GLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQP-ELAGLTYSIVEGNIDSA---FSVDS-EGVIR--TNLELDREILERYSLKVIGTGSGQQI---GTRVDVRVNNLNDNVPSFPMSKPRR---VPENLRVGSYVATVGAKDVDN--LAPLRYFLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTL----------TIKATDGSFDTFTN---LTIFVSDINDNAPTFSKPLYQTTVSPATFSP-GQPFAKIEAHDLD--ARGALTYSLGQGSSSIFRVAP----ESGALFM-----KVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGL-------QIGNLSGEE-----SREFHYRIQDPEASKIFSIDKFGRLFVAGPIDREQRATHEFQ-VEIDN--EMMTSQKVQCKCHVIVLDENDNLPVF-------TSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSL 2329 HSP 7 Score: 66.2402 bits (160), Expect = 1.413e-10 Identity = 118/517 (22.82%), Postives = 219/517 (42.36%), Query Frame = 2
Query: 887 FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF-------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIG-----------YIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGI-----IAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQP 2365
F+INST G I ++ LD ++ E + +++ D G + + S TV + + D ND P + + + ++ I E++ + + + D+D G NG+F+ L+ L DL++ +L + + + D+G+P L + + + N N T + F +I E P G + K++ + GL ++ + F ++S G + N LDR + E +S+ V+ + G+ + ++++ +N ++ +N P +F + P ++L + +G Y VSD NI++F G + A LD E E+ LT+ A DG+ D T T ++ IF++D+NDN+P F + PL T VS + + A +E D A + S+ G +AP +S L K+ + + V D G P S+S+ + + I +++P
Sbjct: 1673 FSINSTTGSISVLP-LDREASQE--HLLIIILTDGG--SRNDSCTVRVTVADQNDNKPQLDAS-TPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSLDLVPETGDLVLRRLSSLQSWK--------IKLRVVDHGVPGLYVEKNLEI----SNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQP--ELAGLTYSIV--------EGNIDSAFSVDSEGVIRTNLELDREIL-ERYSLKVIGTGSGQ-QIGTRVDVRVNNLN-DNVP------SFPMSKPRRVPENLRVGSYVATVGAKDVDNLAPLRYFLVSDSSGQTPTHF------NIDQF----TGTIHLTAPLDFEVLPEHTLTIKATDGSFD-----TFT-NLTIFVSDINDNAPTFSK--PLYQTTVSPATFSPGQPFAK-IEAHDLDARGALTYSLGQGSSSIFRVAP--------ESGALFMKVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEP 2125 HSP 8 Score: 55.8398 bits (133), Expect = 2.070e-7 Identity = 51/207 (24.64%), Postives = 92/207 (44.44%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKD------------EGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI----NKFQISHNGMLQSVAVL 1927
I V + D NDN P+F+ I E + +GT D D +G N ++ ++ + Q+ +L+VN LDR + + +++ D G+PA Q+ +I +ID N+ PVF++S + +V + S L+ + +D D G N++++ IK + F IS +G++ + A L
Sbjct: 108 ILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGDGPKFDVHRFVILQG-NVNNVFKLASRKVNEQL--------QADLVVNGQLDREFRDK-YELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTASVSANISIGSHLI-------TVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASL 297 HSP 9 Score: 55.4546 bits (132), Expect = 2.252e-7 Identity = 87/340 (25.59%), Postives = 136/340 (40.00%), Query Frame = 2
Query: 1388 LPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLI--ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDK-GVNAQLTLAIKDNINK-FQISH---NGMLQSVAV----LDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
PTF T F++ E + IGT + + ++E + D +T+ FL E +G + HLD + V V V + G I+I + + D N+ P F + E + V+D D + + ++ N+N F+++ N LQ+ V LDRE +++Y+L + A DG +I +I D NDN+P+F R+ VS + LI + D D G N+ + IK AP S QS + H +IV+ D G P SSS + IT+ S SP
Sbjct: 19 FPTFCQCLTKFTVPESAQIGTRIGWISG-KREESAAPKYFVVFPDEQTSK-----FLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESGE-----TIDILVEVDDENDNAPSFADQVVKLEISE-------FAQLGTSFALPTVTDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEII---DANDNAPVFSRSR-YTASVSANISIGSHLITVQATDADIGENSRISYDIKK-TSAPSNSNFAISQSGVITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSP 335 HSP 10 Score: 55.4546 bits (132), Expect = 2.471e-7 Identity = 93/452 (20.58%), Postives = 180/452 (39.82%), Query Frame = 2
Query: 449 TLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSS-------IDRETNDRIELVILLTDSGSPPLTGEGI-ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIR--LIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKG---FDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLP----TFSMPATSFSILEHSPIGTVV-----------TKVRALDKDEGLNSQ---------LIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITIN 1693
T F +P + + + YF P + +F K+ +S +D E + ++V + + +GE I I +++ D NDN P+F+ + + E QL + + + D D F + N ++V + A N +++ L+ + D Y ++ A D G+PA I I+D ND P+ S +S ++ N ++ ++ V D D G N + + + + Q+ L+ D + D+G PSL+SS ++T+ ++ + P + + + S ++E+S +G++V TK+R + Q L+ I D T ++ FL+E +G +++ +H L G+I +D+ S+QI I++N
Sbjct: 27 TKFTVPESAQIGTRIGWISGKREESAAPKYF--VVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEE-----SGETIDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALP-TVTDGDGPKFDVHRFVILQGNVNNVFK-LASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFS--RSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAISQSGVITTTASLLPASTHD--------VIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIII-EHPQLLTIGDI-------NDNAPQWHSSQIHISLN 451
BLAST of Protocadherin vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 126.716 bits (317), Expect = 4.150e-29 Identity = 150/534 (28.09%), Postives = 228/534 (42.70%), Query Frame = 2
Query: 593 LKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIIS-LRENFQLNSLLPINVSAVDCDSG-NFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNEL-SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPI-------VDVSVHDLD----QGINGQF----NCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDRE--KEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKD-EGLNSQLIYHISDPR-----TTNQMFPPFLIESNGNLLVNQHLDR--LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSP---------IFHRNFPL 2080
+K +D E +D+ LV++ +D T + I I DVNDN P F KY + + E+ + +L NV A D D ++ Y+ D V F I +G I L+K+LD D + S++FVV A D L V +N+ D+ND PI + E N EPI +DV D D + N ++ N + G F + QN ++ A DRE E + D G+PS +T+ + D+NDN P F S+ E +PIG V A D D E ++ Y +S+ TT++ S G L V Q LD + + F + + VSD A + + + L+D N+ P + +T H V ED VP+ +IG +D D G A+ + + D +F I +G L+ LDRE+ Y L + A D + ++ + V ++L D+NDN P IF N P+
Sbjct: 1393 VKEPLDFEASDQYHLVLIASDGRHNATTN---VYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVL-FNVHATDADQDEKSSRIVYRLEGQGADEV---FRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE----RLFGYIEENR--EPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRI--DQNTG-----KIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQ---SSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDA---EAAVHVALVDRNDHAPHIHGATEH-RVRED-------VPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQM-----VAVYLQDVNDNGPEPYTVPRPCIFRENTPV 1887 HSP 2 Score: 107.457 bits (267), Expect = 3.185e-23 Identity = 147/600 (24.50%), Postives = 244/600 (40.67%), Query Frame = 2
Query: 608 DRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH------FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQP-ALSSSTTVIINIVDVNDELPIISLNKSLK-DITIFENNNLNEPIV-------------DVSVHDLDQGING--------QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILE--------HSPIGTVVTKVRALDKD-EGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPAL-------SNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL--AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKD--------------SGANAVVDLSIKPGIIAPYFSIDRD 2224
DRET R ++ + TD G PL G +++++D+NDN P F Y S+ F+ I V A D D+ + +++Y + T + +N +GEI LIK + + + F V+A D+G P AL SS V +N++D + P + K IT+ EN LN+ I+ DV G G QFN F G++ +++ + L Y+ + + T+T D + S++ V + DVND +P F++ + +I E G + V+A+D D +G +++ Y I + + E G + N+ DR +++ + V SD AL + +++ I + D+N+ P F + + V E + ++ I D DK N + L A I + +G + LD E ++Y L LIA DG RH T +V I + D+NDN+P F + T + + L + D D GA+ V + G I ++DRD
Sbjct: 938 DRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSV-SRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT---QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLD----YEQVNNYTL----------TLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDR-EKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVIT-------IKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG------RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRD 1504 HSP 3 Score: 100.523 bits (249), Expect = 4.741e-21 Identity = 112/380 (29.47%), Postives = 172/380 (45.26%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNE--LSYSFVVVAHDHGQP-ALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAK--HKFDREKEAFAYTTI----------TCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGT------VVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIF---SVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTV 1753
+TI+I DVNDN PTF+ Y +RE+ LN + + V+AVD D+G+ +++Y SV N +F+INS NGEI LD D NE Y F V A DHG+P +LSSS + I + NDE + L S + E+ P++ + D D+ + + G K NL + + + K H A A I +CC Y + TS + + I DVN+N P F A +S + GT + KV A D D N ++Y + T ++ F+I+ G L + H+ + D E V V +D G L + ++ ++DIN+ P F + ++ +V
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTI-LKVTAVDKDTGDNSRITY--SVDN-----HNFSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVF-LPTSQYTAFVAEDAQGGTPVIQIQARDADR---DEVTYSFMDKNGRSTQ-KMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCA-KYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLY--YTQSESRKAFVIDRQTGVLTPSPHV--VFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSV 988 HSP 4 Score: 94.3597 bits (233), Expect = 3.169e-19 Identity = 172/740 (23.24%), Postives = 300/740 (40.54%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELV-------------ILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTH---KYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNG--------EIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNE--------PIVDVSVHDLDQ-GINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQ-------LITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQ---LTLAIKDNINKFQIS-HNGMLQSVAVLDREEKE---EYKLTLIAID-------GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKV-SYKEYVRHELIA-----LFVEDKDSGANAVVDLSIKPGII-------APYFSIDRDRQSV----KLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
D+NDN+P + +P E S+S +GT A D D + + L T E L ++R + + I L+ ++ D+G P L +T+ +LD P + T K I++ EN +LN ++ + AV + YK + S K N E+ +++ LDY+ N +Y+ + A D ++S+ T ++ + DVND +P +++ L TI E NE PIV V D D G + + ++G + K D + ++ KFDREK T+ D + +L + + ++I DVNDN P+F + E G V ++A D D+ +S L YH+ PF + ++ G + V + LD + + ++++ SD A +N + I++ D+N+ P F Q + TV E+ D P+ + + +D D+ + L + F+I ++G ++ V LDR+ + + AID G DVQ+ + D+NDNSPIF P ++ Y E R + + + V+ +D + +I+ GI+ F ID++ + L+R++ SE + I + V DRG P + + I + D +P
Sbjct: 971 DINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEIT----------YSLEIDTTAGEEHQNDLDFFELVNRRSGE-ITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVI-LRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVN--NYTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVD--LFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEET-KHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDK--HSNLRYHLI---GAGGGRIPFGVRTDSGTIFVKEPLD-FEASDQYHLVLIASDGRHNATTN---VYIHIEDVNDNAPQFEQQKYATTVIEEDVD------IPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVN----------VRDINDNSPIF------PERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFI--IEVRANDRGVPSREGFANVTIKVTDMNDNAP 1659 HSP 5 Score: 77.7962 bits (190), Expect = 3.936e-14 Identity = 139/626 (22.20%), Postives = 249/626 (39.78%), Query Frame = 2
Query: 614 ETNDRIELVILLTDSGS----PPLTGEGIIT--IQILDVNDNYPTF---STHKYIISLREN-FQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFD--------REKEAFAYTTITCCDYGIP-SLTSSQLITVIIVDVNDNLPTFSMP---ATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDP----RTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPED--PSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDGT----PDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQP 2365
E + I L +++ D GS P T T I I DVN+N P F + + I + E ++ + + V A D DS G + Y + ++S ++ F I+ G + + +D V A D G L + +VD+ND P ++ FE + ++ V D D N + L + +++ +DL ++L+ + + + + F + I D GIP +L SS +T+ ++D P + ++ E+ + V+ + RA+ + NS +IY ++ F F NGN V + LD E +++ + +D S + + + D+N+ P F F T+ E+ P++HL + A+ G ++ I N + H G + DRE+ + Y LT+ A D + P + V I +ND+NDN+P F + +V E H++I + D D +N L G P F + D ++ + L E + L++I D GR ++++ I I ++D+ P
Sbjct: 820 EAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSES-RKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFE--AVGTSVITVFAFDNDAAHNAEITYSL---EIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVI-ADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKT-FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYI-GRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRIP-FGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNATTNVYIHIEDVNDNAP 1434 HSP 6 Score: 70.8626 bits (172), Expect = 5.772e-12 Identity = 76/256 (29.69%), Postives = 116/256 (45.31%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGE---IFSVIVVVSDHGRP-ALSNQIEITINLIDINNCPPVF-NQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD-------NINKFQI-SHNGMLQ---SVAVLDREEKEE-YKLTLIAI-DGTPDV--QIRHTVTGSVVIFLNDLNDNSPIF 2062
+T+ I DVNDN+PTF+ P + + E P+ + KV A+DKD G NS++ Y + + F I SNG + LD E ++ V DHG P +LS+ I I + N+ VF S + V ED P++ I D D+ ++T + D +N F I H G+++ V+ D E E LT+I DG+ V HT +++I + D+N+N P F
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHN--------FSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVI-------QIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEF 865 HSP 7 Score: 58.5362 bits (140), Expect = 2.857e-8 Identity = 123/558 (22.04%), Postives = 213/558 (38.17%), Query Frame = 2
Query: 377 DLNDNAPHWPKPIELSISENA----FIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILL--TDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKL---------SYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYD-----SGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPT-FSMPATSFSILEHSPIGTVVT-KVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE---------------------SNGNLLVN--QHLDRL--LDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGML 1909
D+NDN+P +P+ + I EN G F A D D ++ + + D++ ++ S+DRE + E +I + D G P G +TI++ D+NDN P F +Y S+ E + + + ++ SA D D + Y + ++ DS + S+ G +R+ + LDY+ G L HD + V + +VD ND P I + + E+ I + D D G +F Q+ + L H DRE A I Y + Q++ V + DVNDN P +++P E++P+ + T ++RA D+D T + PPF +E NG++ + Q DR + G+I + ++++D R N+ + + + D+N+ + T H + +L + K IG + V D D T + KD+ F++S G +
Sbjct: 1538 DINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMR-SLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAV-MSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQ------SSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHD-------AEAAVHVALVDRNDHAPHI---HGATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGT------LRVAHTLDREDIAVYNLIIEA--YDNSNNIGRQMVAVYLQDVNDNGPEPYTVPRPCI-FRENTPVNQLGTCEIRATDRD----------------TAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILEIPLILAD--RAGRRNEASVHVIIGDLNDNTMHDGRMTIHV------NSYLGRL-KETVIGRVYVDDADDWDLGDKTFSWKDSRPGFELSDKGSI 2043
BLAST of Protocadherin vs. Ensembl Celegans
Match: hmr-1 (Cadherin-related hmr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q967F4]) HSP 1 Score: 126.716 bits (317), Expect = 4.150e-29 Identity = 150/534 (28.09%), Postives = 228/534 (42.70%), Query Frame = 2
Query: 593 LKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIIS-LRENFQLNSLLPINVSAVDCDSG-NFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNEL-SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPI-------VDVSVHDLD----QGINGQF----NCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDRE--KEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKD-EGLNSQLIYHISDPR-----TTNQMFPPFLIESNGNLLVNQHLDR--LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSP---------IFHRNFPL 2080
+K +D E +D+ LV++ +D T + I I DVNDN P F KY + + E+ + +L NV A D D ++ Y+ D V F I +G I L+K+LD D + S++FVV A D L V +N+ D+ND PI + E N EPI +DV D D + N ++ N + G F + QN ++ A DRE E + D G+PS +T+ + D+NDN P F S+ E +PIG V A D D E ++ Y +S+ TT++ S G L V Q LD + + F + + VSD A + + + L+D N+ P + +T H V ED VP+ +IG +D D G A+ + + D +F I +G L+ LDRE+ Y L + A D + ++ + V ++L D+NDN P IF N P+
Sbjct: 1393 VKEPLDFEASDQYHLVLIASDGRHNATTN---VYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVL-FNVHATDADQDEKSSRIVYRLEGQGADEV---FRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVNVRDINDNSPIFPE----RLFGYIEENR--EPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRI--DQNTG-----KIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQ---SSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDA---EAAVHVALVDRNDHAPHIHGATEH-RVRED-------VPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQM-----VAVYLQDVNDNGPEPYTVPRPCIFRENTPV 1887 HSP 2 Score: 107.457 bits (267), Expect = 3.185e-23 Identity = 147/600 (24.50%), Postives = 244/600 (40.67%), Query Frame = 2
Query: 608 DRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH------FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQP-ALSSSTTVIINIVDVNDELPIISLNKSLK-DITIFENNNLNEPIV-------------DVSVHDLDQGING--------QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILE--------HSPIGTVVTKVRALDKD-EGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPAL-------SNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL--AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKD--------------SGANAVVDLSIKPGIIAPYFSIDRD 2224
DRET R ++ + TD G PL G +++++D+NDN P F Y S+ F+ I V A D D+ + +++Y + T + +N +GEI LIK + + + F V+A D+G P AL SS V +N++D + P + K IT+ EN LN+ I+ DV G G QFN F G++ +++ + L Y+ + + T+T D + S++ V + DVND +P F++ + +I E G + V+A+D D +G +++ Y I + + E G + N+ DR +++ + V SD AL + +++ I + D+N+ P F + + V E + ++ I D DK N + L A I + +G + LD E ++Y L LIA DG RH T +V I + D+NDN+P F + T + + L + D D GA+ V + G I ++DRD
Sbjct: 938 DRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSV-SRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT---QKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLD----YEQVNNYTL----------TLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDR-EKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVIT-------IKAHDLDKHSNLRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG------RHNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRD 1504 HSP 3 Score: 100.523 bits (249), Expect = 4.741e-21 Identity = 112/380 (29.47%), Postives = 172/380 (45.26%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNE--LSYSFVVVAHDHGQP-ALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAK--HKFDREKEAFAYTTI----------TCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGT------VVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIF---SVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTV 1753
+TI+I DVNDN PTF+ Y +RE+ LN + + V+AVD D+G+ +++Y SV N +F+INS NGEI LD D NE Y F V A DHG+P +LSSS + I + NDE + L S + E+ P++ + D D+ + + G K NL + + + K H A A I +CC Y + TS + + I DVN+N P F A +S + GT + KV A D D N ++Y + T ++ F+I+ G L + H+ + D E V V +D G L + ++ ++DIN+ P F + ++ +V
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTI-LKVTAVDKDTGDNSRITY--SVDN-----HNFSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVF-LPTSQYTAFVAEDAQGGTPVIQIQARDADR---DEVTYSFMDKNGRSTQ-KMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCA-KYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLY--YTQSESRKAFVIDRQTGVLTPSPHV--VFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSV 988 HSP 4 Score: 94.3597 bits (233), Expect = 3.169e-19 Identity = 172/740 (23.24%), Postives = 300/740 (40.54%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELV-------------ILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTH---KYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNG--------EIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNE--------PIVDVSVHDLDQ-GINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQ-------LITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQ---LTLAIKDNINKFQIS-HNGMLQSVAVLDREEKE---EYKLTLIAID-------GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKV-SYKEYVRHELIA-----LFVEDKDSGANAVVDLSIKPGII-------APYFSIDRDRQSV----KLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
D+NDN+P + +P E S+S +GT A D D + + L T E L ++R + + I L+ ++ D+G P L +T+ +LD P + T K I++ EN +LN ++ + AV + YK + S K N E+ +++ LDY+ N +Y+ + A D ++S+ T ++ + DVND +P +++ L TI E NE PIV V D D G + + ++G + K D + ++ KFDREK T+ D + +L + + ++I DVNDN P+F + E G V ++A D D+ +S L YH+ PF + ++ G + V + LD + + ++++ SD A +N + I++ D+N+ P F Q + TV E+ D P+ + + +D D+ + L + F+I ++G ++ V LDR+ + + AID G DVQ+ + D+NDNSPIF P ++ Y E R + + + V+ +D + +I+ GI+ F ID++ + L+R++ SE + I + V DRG P + + I + D +P
Sbjct: 971 DINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEIT----------YSLEIDTTAGEEHQNDLDFFELVNRRSGE-ITLIKPIPMKTQKFIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVI-LRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVN--NYTLTLTATDM-TSRVASTKTFVVEVRDVNDVVPQFTVD--LFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEET-KHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDK--HSNLRYHLI---GAGGGRIPFGVRTDSGTIFVKEPLD-FEASDQYHLVLIASDGRHNATTN---VYIHIEDVNDNAPQFEQQKYATTVIEEDVD------IPKVLFNVHATDADQDEKSSRIVYRLEGQGADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADVQVN----------VRDINDNSPIF------PERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFI--IEVRANDRGVPSREGFANVTIKVTDMNDNAP 1659 HSP 5 Score: 77.7962 bits (190), Expect = 3.936e-14 Identity = 139/626 (22.20%), Postives = 249/626 (39.78%), Query Frame = 2
Query: 614 ETNDRIELVILLTDSGS----PPLTGEGIIT--IQILDVNDNYPTF---STHKYIISLREN-FQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFD--------REKEAFAYTTITCCDYGIP-SLTSSQLITVIIVDVNDNLPTFSMP---ATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDP----RTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPED--PSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDGT----PDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQP 2365
E + I L +++ D GS P T T I I DVN+N P F + + I + E ++ + + V A D DS G + Y + ++S ++ F I+ G + + +D V A D G L + +VD+ND P ++ FE + ++ V D D N + L + +++ +DL ++L+ + + + + F + I D GIP +L SS +T+ ++D P + ++ E+ + V+ + RA+ + NS +IY ++ F F NGN V + LD E +++ + +D S + + + D+N+ P F F T+ E+ P++HL + A+ G ++ I N + H G + DRE+ + Y LT+ A D + P + V I +ND+NDN+P F + +V E H++I + D D +N L G P F + D ++ + L E + L++I D GR ++++ I I ++D+ P
Sbjct: 820 EAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQSES-RKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFE--AVGTSVITVFAFDNDAAHNAEITYSL---EIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKTQKFIFNVI-ADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATDMTSRVASTKT-FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYI-GRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRIP-FGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNATTNVYIHIEDVNDNAP 1434 HSP 6 Score: 70.8626 bits (172), Expect = 5.772e-12 Identity = 76/256 (29.69%), Postives = 116/256 (45.31%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGE---IFSVIVVVSDHGRP-ALSNQIEITINLIDINNCPPVF-NQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD-------NINKFQI-SHNGMLQ---SVAVLDREEKEE-YKLTLIAI-DGTPDV--QIRHTVTGSVVIFLNDLNDNSPIF 2062
+T+ I DVNDN+PTF+ P + + E P+ + KV A+DKD G NS++ Y + + F I SNG + LD E ++ V DHG P +LS+ I I + N+ VF S + V ED P++ I D D+ ++T + D +N F I H G+++ V+ D E E LT+I DG+ V HT +++I + D+N+N P F
Sbjct: 628 LTIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHN--------FSINSNGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGGTPVI-------QIQARDADRD---EVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEF 865 HSP 7 Score: 58.5362 bits (140), Expect = 2.857e-8 Identity = 123/558 (22.04%), Postives = 213/558 (38.17%), Query Frame = 2
Query: 377 DLNDNAPHWPKPIELSISENA----FIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILL--TDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKL---------SYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYD-----SGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPT-FSMPATSFSILEHSPIGTVVT-KVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE---------------------SNGNLLVN--QHLDRL--LDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGML 1909
D+NDN+P +P+ + I EN G F A D D ++ + + D++ ++ S+DRE + E +I + D G P G +TI++ D+NDN P F +Y S+ E + + + ++ SA D D + Y + ++ DS + S+ G +R+ + LDY+ G L HD + V + +VD ND P I + + E+ I + D D G +F Q+ + L H DRE A I Y + Q++ V + DVNDN P +++P E++P+ + T ++RA D+D T + PPF +E NG++ + Q DR + G+I + ++++D R N+ + + + D+N+ + T H + +L + K IG + V D D T + KD+ F++S G +
Sbjct: 1538 DINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVRNKLINGESVFRIDQNTGKIFAMR-SLDREISSEREFIIEVRANDRGVPSREGFANVTIKVTDMNDNAPFFEKTRYEGSVEETAPIGAAV-MSFSAFDADEEAKDNVFTYQLSEESDYFYVTTDKDSKQ------SSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHD-------AEAAVHVALVDRNDHAPHI---HGATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGT------LRVAHTLDREDIAVYNLIIEA--YDNSNNIGRQMVAVYLQDVNDNGPEPYTVPRPCI-FRENTPVNQLGTCEIRATDRD----------------TAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGSMTITPLQEFDREAPVPGKILEIPLILAD--RAGRRNEASVHVIIGDLNDNTMHDGRMTIHV------NSYLGRL-KETVIGRVYVDDADDWDLGDKTFSWKDSRPGFELSDKGSI 2043
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0339463) HSP 1 Score: 216.083 bits (549), Expect = 7.677e-57 Identity = 202/693 (29.15%), Postives = 317/693 (45.74%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKL-------KLKSSIDRETNDRIELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK--GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVN--QHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINK------FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVV-----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D ND++P + + E SI E A +G+ A D D + + D A L D E ++ +SS+DRET+D L++ D + S T + +++LD NDNYP FS Y + + E+ + ++ A D D GN + Y NT S F+I+S +G++ L+K LDY+S SY V+ A D G P+ S++T +++N++D ND P ++ + ++ EN + I+ V +D D+G N + + I + F L D + DRE++ + D G+P ++S + + + DVNDN P F+ ++ E P GT VT V A D DE +S+L Y I TT F I S NG L+ Q LD + + GR S+ + IN+ D NN P+F + + +V ED P + ++ +D D GVNAQ+T ++ +++IN F I+ G + + A LDRE Y LT+ A DG P + + T V I + D+NDN+P F PL + V +I + D D G N + D I+ G F ID +++ N+ L E + L I D+G PP SS++E+QI ++D
Sbjct: 456 DCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQD----IGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS---QFSIDSMSGDVSLVKPLDYESVR--SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE--SVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDNFPLAV-----DPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI----TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGR---SDTATVHINITDANNFAPIFENAPYSASVFED-------APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSL----SDTTDVEIGVTDVNDNAPAFKS--PLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDG----SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED 1105 HSP 2 Score: 179.104 bits (453), Expect = 3.491e-45 Identity = 173/580 (29.83%), Postives = 259/580 (44.66%), Query Frame = 2
Query: 377 DLNDNAPH-WPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFL----IGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF 2074
D NDNAP + + S+ EN +G A D D + ++ + F LA P Q K +DRE R ++ D G PP + + I + DVNDN P F+ Y ++ E+ Q V+A D D + +L Y+ + NT + FAI S NG I + +SLDY E + V A D G S + TV INI D N+ PI + ++FE+ + ++ VS D D G+N Q L I G F N I + DRE + T+T D G PSL+ + + + + DVNDN P F P SILE + +GT V +V A D D GLN ++ Y +SD + F + ++G + N+ LDR +F + + D G P LS+ +E+ I L D+N+ PP F VPE+ P +G I D D+GVNA + +I D+ N F + S L ++ LD E + + L+ +P ++ + I + D+NDN+P+ R+F
Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDN-FPLAVDPRTGWVQTIK-----PLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED-QPPGTPVTTVTATDPDEDS--RLHYEITTGNT---RGRFAITSQNGRGLITIAQSLDYK--QEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPI--FENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI---VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF--VIDPTSGTIRTNKGLDR-ESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-------SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRAASPPLR----NDAHIEILVTDVNDNAPVL-RDF 1223 HSP 3 Score: 171.014 bits (432), Expect = 1.330e-42 Identity = 158/550 (28.73%), Postives = 253/550 (46.00%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP-PFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI---NKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSI 2215
+ L +D E+ LVI D GSP + + + ++D NDN P F T ++ S+ EN + + I V A D D G +++Y S+S D A++ G ++ IK LD + + ++F VVA D G P S+S++V+I + DVND P + N + + E+ P+ V+ D D+ + +G + QN LI D ++E T+ D G S T++ + + I D N+ P F S S+ E +P+GT V V A D D G+N+Q+ Y +++ P PF I G ++ N LDR + + V D G P+LS+ ++ I + D+N+ P F + ++ ED LV ++ +A SD D G+N ++ + D F I +G +++ LDRE + LT IA+D G+P + + T V I L D+ND+ P F + + V V + + D D G NAVV SI G + FS+
Sbjct: 641 VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITY--SISERDD-NFPLAVDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP--AFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITI----AQSLDYKQEKRFLLTVAATDSGGRSDTAT--VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSG-YLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA-----LVGT--SVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL----SSTVEVQIRLEDVNDSPPTFASD-KITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSL 1163 HSP 4 Score: 164.081 bits (414), Expect = 1.824e-40 Identity = 160/609 (26.27%), Postives = 270/609 (44.33%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRH-----FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN---NNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS-DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN---GMLQSVAVLDREEKEEYKLTLIAID--GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP----GIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+S+DRE D ++ TD PP +G + + +LD ND+ PTF ++ S+RE + S + I + A D D G ++ Y +V++ + + F I+S +G I SLD ++ + SY +V A D +++ +V + ++D ND P S + + + E+ + + + D DQG N +IG ++S D+ + + + D E I D G PS +++ + V ++D NDN P F S+LE+ P+G + +V+A D DEG N+++ Y IS+ R N FP + G + + LDR G F+ VV D G P S + I + D+N+ P FN + V ED P+ + +D D+ + + +F I+ G++ LD ++++ + LT+ A D G D T +V I + D N+ +PIF N P V V ++ + D D G NA + S+ G+ +P FSI+ ++ N L E + L V KD G P S + +++I + D
Sbjct: 420 ASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSD--SYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPL-----DYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDN--FPLAVDPRTGWVQTIKPLDREEQGR-FAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTT-------VTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSD-------TATVHINITDANNFAPIFE-NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999 HSP 5 Score: 93.9745 bits (232), Expect = 6.656e-19 Identity = 92/360 (25.56%), Postives = 156/360 (43.33%), Query Frame = 2
Query: 1373 DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-----------DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV-HFNES 2401
++ + P F S+LE P G VT VRA D ++ + + D R+ + F ++S G + + LDR L+D F V V +D P S + +N++D N+ P F F ++ E + ++ + +D D G NA++ I+ + F+I S +G++ + + LDRE + Y L + A D R T T SV + + D NDN P F R + + +A + D D G NA + +I G FSID V L + L E ++L++ +D G P +S++ ++ + + D+ +P+ F ES
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSL----FKVDSRTGVVTTSASLDRELMDVHYFRV--VATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVIT-------LRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQES 697
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0303223) HSP 1 Score: 215.698 bits (548), Expect = 8.907e-57 Identity = 202/693 (29.15%), Postives = 317/693 (45.74%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKL-------KLKSSIDRETNDRIELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK--GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVN--QHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINK------FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVV-----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D ND++P + + E SI E A +G+ A D D + + D A L D E ++ +SS+DRET+D L++ D + S T + +++LD NDNYP FS Y + + E+ + ++ A D D GN + Y NT S F+I+S +G++ L+K LDY+S SY V+ A D G P+ S++T +++N++D ND P ++ + ++ EN + I+ V +D D+G N + + I + F L D + DRE++ + D G+P ++S + + + DVNDN P F+ ++ E P GT VT V A D DE +S+L Y I TT F I S NG L+ Q LD + + GR S+ + IN+ D NN P+F + + +V ED P + ++ +D D GVNAQ+T ++ +++IN F I+ G + + A LDRE Y LT+ A DG P + + T V I + D+NDN+P F PL + V +I + D D G N + D I+ G F ID +++ N+ L E + L I D+G PP SS++E+QI ++D
Sbjct: 456 DCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQD----IGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS---QFSIDSMSGDVSLVKPLDYESVR--SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE--SVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDNFPLAV-----DPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI----TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGR---SDTATVHINITDANNFAPIFENAPYSASVFED-------APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSL----SDTTDVEIGVTDVNDNAPAFKS--PLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDG----SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED 1105 HSP 2 Score: 178.718 bits (452), Expect = 4.639e-45 Identity = 173/580 (29.83%), Postives = 259/580 (44.66%), Query Frame = 2
Query: 377 DLNDNAPH-WPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFL----IGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF 2074
D NDNAP + + S+ EN +G A D D + ++ + F LA P Q K +DRE R ++ D G PP + + I + DVNDN P F+ Y ++ E+ Q V+A D D + +L Y+ + NT + FAI S NG I + +SLDY E + V A D G S + TV INI D N+ PI + ++FE+ + ++ VS D D G+N Q L I G F N I + DRE + T+T D G PSL+ + + + + DVNDN P F P SILE + +GT V +V A D D GLN ++ Y +SD + F + ++G + N+ LDR +F + + D G P LS+ +E+ I L D+N+ PP F VPE+ P +G I D D+GVNA + +I D+ N F + S L ++ LD E + + L+ +P ++ + I + D+NDN+P+ R+F
Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDN-FPLAVDPRTGWVQTIK-----PLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED-QPPGTPVTTVTATDPDEDS--RLHYEITTGNT---RGRFAITSQNGRGLITIAQSLDYK--QEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPI--FENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI---VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF--VIDPTSGTIRTNKGLDR-ESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-------SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRAASPPLR----NDAHIEILVTDVNDNAPVL-RDF 1223 HSP 3 Score: 170.629 bits (431), Expect = 1.720e-42 Identity = 158/550 (28.73%), Postives = 253/550 (46.00%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP-PFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI---NKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSI 2215
+ L +D E+ LVI D GSP + + + ++D NDN P F T ++ S+ EN + + I V A D D G +++Y S+S D A++ G ++ IK LD + + ++F VVA D G P S+S++V+I + DVND P + N + + E+ P+ V+ D D+ + +G + QN LI D ++E T+ D G S T++ + + I D N+ P F S S+ E +P+GT V V A D D G+N+Q+ Y +++ P PF I G ++ N LDR + + V D G P+LS+ ++ I + D+N+ P F + ++ ED LV ++ +A SD D G+N ++ + D F I +G +++ LDRE + LT IA+D G+P + + T V I L D+ND+ P F + + V V + + D D G NAVV SI G + FS+
Sbjct: 641 VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITY--SISERDD-NFPLAVDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP--AFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITI----AQSLDYKQEKRFLLTVAATDSGGRSDTAT--VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSG-YLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA-----LVGT--SVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL----SSTVEVQIRLEDVNDSPPTFASD-KITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSL 1163 HSP 4 Score: 163.696 bits (413), Expect = 2.440e-40 Identity = 160/609 (26.27%), Postives = 270/609 (44.33%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRH-----FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN---NNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS-DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN---GMLQSVAVLDREEKEEYKLTLIAID--GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP----GIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+S+DRE D ++ TD PP +G + + +LD ND+ PTF ++ S+RE + S + I + A D D G ++ Y +V++ + + F I+S +G I SLD ++ + SY +V A D +++ +V + ++D ND P S + + + E+ + + + D DQG N +IG ++S D+ + + + D E I D G PS +++ + V ++D NDN P F S+LE+ P+G + +V+A D DEG N+++ Y IS+ R N FP + G + + LDR G F+ VV D G P S + I + D+N+ P FN + V ED P+ + +D D+ + + +F I+ G++ LD ++++ + LT+ A D G D T +V I + D N+ +PIF N P V V ++ + D D G NA + S+ G+ +P FSI+ ++ N L E + L V KD G P S + +++I + D
Sbjct: 420 ASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSD--SYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPL-----DYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDN--FPLAVDPRTGWVQTIKPLDREEQGR-FAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVT-------TVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSD-------TATVHINITDANNFAPIFE-NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999 HSP 5 Score: 93.5893 bits (231), Expect = 7.877e-19 Identity = 92/360 (25.56%), Postives = 156/360 (43.33%), Query Frame = 2
Query: 1373 DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-----------DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV-HFNES 2401
++ + P F S+LE P G VT VRA D ++ + + D R+ + F ++S G + + LDR L+D F V V +D P S + +N++D N+ P F F ++ E + ++ + +D D G NA++ I+ + F+I S +G++ + + LDRE + Y L + A D R T T SV + + D NDN P F R + + +A + D D G NA + +I G FSID V L + L E ++L++ +D G P +S++ ++ + + D+ +P+ F ES
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSL----FKVDSRTGVVTTSASLDRELMDVHYFRV--VATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVIT-------LRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQES 697
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0088214) HSP 1 Score: 215.698 bits (548), Expect = 8.907e-57 Identity = 202/693 (29.15%), Postives = 317/693 (45.74%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKL-------KLKSSIDRETNDRIELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK--GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVN--QHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINK------FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVV-----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D ND++P + + E SI E A +G+ A D D + + D A L D E ++ +SS+DRET+D L++ D + S T + +++LD NDNYP FS Y + + E+ + ++ A D D GN + Y NT S F+I+S +G++ L+K LDY+S SY V+ A D G P+ S++T +++N++D ND P ++ + ++ EN + I+ V +D D+G N + + I + F L D + DRE++ + D G+P ++S + + + DVNDN P F+ ++ E P GT VT V A D DE +S+L Y I TT F I S NG L+ Q LD + + GR S+ + IN+ D NN P+F + + +V ED P + ++ +D D GVNAQ+T ++ +++IN F I+ G + + A LDRE Y LT+ A DG P + + T V I + D+NDN+P F PL + V +I + D D G N + D I+ G F ID +++ N+ L E + L I D+G PP SS++E+QI ++D
Sbjct: 456 DCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQD----IGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS---QFSIDSMSGDVSLVKPLDYESVR--SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE--SVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDNFPLAV-----DPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI----TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGR---SDTATVHINITDANNFAPIFENAPYSASVFED-------APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSL----SDTTDVEIGVTDVNDNAPAFKS--PLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDG----SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED 1105 HSP 2 Score: 178.718 bits (452), Expect = 4.639e-45 Identity = 173/580 (29.83%), Postives = 259/580 (44.66%), Query Frame = 2
Query: 377 DLNDNAPH-WPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFL----IGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF 2074
D NDNAP + + S+ EN +G A D D + ++ + F LA P Q K +DRE R ++ D G PP + + I + DVNDN P F+ Y ++ E+ Q V+A D D + +L Y+ + NT + FAI S NG I + +SLDY E + V A D G S + TV INI D N+ PI + ++FE+ + ++ VS D D G+N Q L I G F N I + DRE + T+T D G PSL+ + + + + DVNDN P F P SILE + +GT V +V A D D GLN ++ Y +SD + F + ++G + N+ LDR +F + + D G P LS+ +E+ I L D+N+ PP F VPE+ P +G I D D+GVNA + +I D+ N F + S L ++ LD E + + L+ +P ++ + I + D+NDN+P+ R+F
Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDN-FPLAVDPRTGWVQTIK-----PLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED-QPPGTPVTTVTATDPDEDS--RLHYEITTGNT---RGRFAITSQNGRGLITIAQSLDYK--QEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPI--FENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI---VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF--VIDPTSGTIRTNKGLDR-ESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-------SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRAASPPLR----NDAHIEILVTDVNDNAPVL-RDF 1223 HSP 3 Score: 170.629 bits (431), Expect = 1.720e-42 Identity = 158/550 (28.73%), Postives = 253/550 (46.00%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP-PFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI---NKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSI 2215
+ L +D E+ LVI D GSP + + + ++D NDN P F T ++ S+ EN + + I V A D D G +++Y S+S D A++ G ++ IK LD + + ++F VVA D G P S+S++V+I + DVND P + N + + E+ P+ V+ D D+ + +G + QN LI D ++E T+ D G S T++ + + I D N+ P F S S+ E +P+GT V V A D D G+N+Q+ Y +++ P PF I G ++ N LDR + + V D G P+LS+ ++ I + D+N+ P F + ++ ED LV ++ +A SD D G+N ++ + D F I +G +++ LDRE + LT IA+D G+P + + T V I L D+ND+ P F + + V V + + D D G NAVV SI G + FS+
Sbjct: 641 VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITY--SISERDD-NFPLAVDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP--AFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITI----AQSLDYKQEKRFLLTVAATDSGGRSDTAT--VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSG-YLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA-----LVGT--SVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL----SSTVEVQIRLEDVNDSPPTFASD-KITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSL 1163 HSP 4 Score: 163.696 bits (413), Expect = 2.440e-40 Identity = 160/609 (26.27%), Postives = 270/609 (44.33%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRH-----FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN---NNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS-DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN---GMLQSVAVLDREEKEEYKLTLIAID--GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP----GIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+S+DRE D ++ TD PP +G + + +LD ND+ PTF ++ S+RE + S + I + A D D G ++ Y +V++ + + F I+S +G I SLD ++ + SY +V A D +++ +V + ++D ND P S + + + E+ + + + D DQG N +IG ++S D+ + + + D E I D G PS +++ + V ++D NDN P F S+LE+ P+G + +V+A D DEG N+++ Y IS+ R N FP + G + + LDR G F+ VV D G P S + I + D+N+ P FN + V ED P+ + +D D+ + + +F I+ G++ LD ++++ + LT+ A D G D T +V I + D N+ +PIF N P V V ++ + D D G NA + S+ G+ +P FSI+ ++ N L E + L V KD G P S + +++I + D
Sbjct: 420 ASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSD--SYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPL-----DYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDN--FPLAVDPRTGWVQTIKPLDREEQGR-FAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVT-------TVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSD-------TATVHINITDANNFAPIFE-NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999 HSP 5 Score: 93.5893 bits (231), Expect = 7.877e-19 Identity = 92/360 (25.56%), Postives = 156/360 (43.33%), Query Frame = 2
Query: 1373 DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-----------DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV-HFNES 2401
++ + P F S+LE P G VT VRA D ++ + + D R+ + F ++S G + + LDR L+D F V V +D P S + +N++D N+ P F F ++ E + ++ + +D D G NA++ I+ + F+I S +G++ + + LDRE + Y L + A D R T T SV + + D NDN P F R + + +A + D D G NA + +I G FSID V L + L E ++L++ +D G P +S++ ++ + + D+ +P+ F ES
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSL----FKVDSRTGVVTTSASLDRELMDVHYFRV--VATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVIT-------LRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQES 697
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0304899) HSP 1 Score: 215.698 bits (548), Expect = 9.143e-57 Identity = 202/693 (29.15%), Postives = 317/693 (45.74%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKL-------KLKSSIDRETNDRIELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK--GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVN--QHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINK------FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVV-----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D ND++P + + E SI E A +G+ A D D + + D A L D E ++ +SS+DRET+D L++ D + S T + +++LD NDNYP FS Y + + E+ + ++ A D D GN + Y NT S F+I+S +G++ L+K LDY+S SY V+ A D G P+ S++T +++N++D ND P ++ + ++ EN + I+ V +D D+G N + + I + F L D + DRE++ + D G+P ++S + + + DVNDN P F+ ++ E P GT VT V A D DE +S+L Y I TT F I S NG L+ Q LD + + GR S+ + IN+ D NN P+F + + +V ED P + ++ +D D GVNAQ+T ++ +++IN F I+ G + + A LDRE Y LT+ A DG P + + T V I + D+NDN+P F PL + V +I + D D G N + D I+ G F ID +++ N+ L E + L I D+G PP SS++E+QI ++D
Sbjct: 456 DCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQD----IGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS---QFSIDSMSGDVSLVKPLDYESVR--SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE--SVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDNFPLAV-----DPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI----TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGR---SDTATVHINITDANNFAPIFENAPYSASVFED-------APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSL----SDTTDVEIGVTDVNDNAPAFKS--PLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDG----SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED 1105 HSP 2 Score: 178.718 bits (452), Expect = 5.014e-45 Identity = 173/580 (29.83%), Postives = 259/580 (44.66%), Query Frame = 2
Query: 377 DLNDNAPH-WPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFL----IGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF 2074
D NDNAP + + S+ EN +G A D D + ++ + F LA P Q K +DRE R ++ D G PP + + I + DVNDN P F+ Y ++ E+ Q V+A D D + +L Y+ + NT + FAI S NG I + +SLDY E + V A D G S + TV INI D N+ PI + ++FE+ + ++ VS D D G+N Q L I G F N I + DRE + T+T D G PSL+ + + + + DVNDN P F P SILE + +GT V +V A D D GLN ++ Y +SD + F + ++G + N+ LDR +F + + D G P LS+ +E+ I L D+N+ PP F VPE+ P +G I D D+GVNA + +I D+ N F + S L ++ LD E + + L+ +P ++ + I + D+NDN+P+ R+F
Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDN-FPLAVDPRTGWVQTIK-----PLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED-QPPGTPVTTVTATDPDEDS--RLHYEITTGNT---RGRFAITSQNGRGLITIAQSLDYK--QEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPI--FENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI---VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF--VIDPTSGTIRTNKGLDR-ESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-------SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRAASPPLR----NDAHIEILVTDVNDNAPVL-RDF 1223 HSP 3 Score: 170.629 bits (431), Expect = 1.720e-42 Identity = 158/550 (28.73%), Postives = 253/550 (46.00%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP-PFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI---NKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSI 2215
+ L +D E+ LVI D GSP + + + ++D NDN P F T ++ S+ EN + + I V A D D G +++Y S+S D A++ G ++ IK LD + + ++F VVA D G P S+S++V+I + DVND P + N + + E+ P+ V+ D D+ + +G + QN LI D ++E T+ D G S T++ + + I D N+ P F S S+ E +P+GT V V A D D G+N+Q+ Y +++ P PF I G ++ N LDR + + V D G P+LS+ ++ I + D+N+ P F + ++ ED LV ++ +A SD D G+N ++ + D F I +G +++ LDRE + LT IA+D G+P + + T V I L D+ND+ P F + + V V + + D D G NAVV SI G + FS+
Sbjct: 641 VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITY--SISERDD-NFPLAVDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP--AFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITI----AQSLDYKQEKRFLLTVAATDSGGRSDTAT--VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSG-YLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA-----LVGT--SVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL----SSTVEVQIRLEDVNDSPPTFASD-KITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSL 1163 HSP 4 Score: 163.31 bits (412), Expect = 2.658e-40 Identity = 160/609 (26.27%), Postives = 270/609 (44.33%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRH-----FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN---NNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS-DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN---GMLQSVAVLDREEKEEYKLTLIAID--GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP----GIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+S+DRE D ++ TD PP +G + + +LD ND+ PTF ++ S+RE + S + I + A D D G ++ Y +V++ + + F I+S +G I SLD ++ + SY +V A D +++ +V + ++D ND P S + + + E+ + + + D DQG N +IG ++S D+ + + + D E I D G PS +++ + V ++D NDN P F S+LE+ P+G + +V+A D DEG N+++ Y IS+ R N FP + G + + LDR G F+ VV D G P S + I + D+N+ P FN + V ED P+ + +D D+ + + +F I+ G++ LD ++++ + LT+ A D G D T +V I + D N+ +PIF N P V V ++ + D D G NA + S+ G+ +P FSI+ ++ N L E + L V KD G P S + +++I + D
Sbjct: 420 ASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSD--SYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPL-----DYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDN--FPLAVDPRTGWVQTIKPLDREEQGR-FAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVT-------TVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSD-------TATVHINITDANNFAPIFE-NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999 HSP 5 Score: 93.5893 bits (231), Expect = 8.644e-19 Identity = 92/360 (25.56%), Postives = 156/360 (43.33%), Query Frame = 2
Query: 1373 DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-----------DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV-HFNES 2401
++ + P F S+LE P G VT VRA D ++ + + D R+ + F ++S G + + LDR L+D F V V +D P S + +N++D N+ P F F ++ E + ++ + +D D G NA++ I+ + F+I S +G++ + + LDRE + Y L + A D R T T SV + + D NDN P F R + + +A + D D G NA + +I G FSID V L + L E ++L++ +D G P +S++ ++ + + D+ +P+ F ES
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSL----FKVDSRTGVVTTSASLDRELMDVHYFRV--VATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVIT-------LRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQES 697
BLAST of Protocadherin vs. Ensembl Fly
Match: stan (gene:FBgn0024836 transcript:FBtr0300578) HSP 1 Score: 215.698 bits (548), Expect = 9.143e-57 Identity = 202/693 (29.15%), Postives = 317/693 (45.74%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKL-------KLKSSIDRETNDRIELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK--GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVN--QHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINK------FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPL-PTKVSYKEYVRHELIALFVEDKDSGANAVV-----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D ND++P + + E SI E A +G+ A D D + + D A L D E ++ +SS+DRET+D L++ D + S T + +++LD NDNYP FS Y + + E+ + ++ A D D GN + Y NT S F+I+S +G++ L+K LDY+S SY V+ A D G P+ S++T +++N++D ND P ++ + ++ EN + I+ V +D D+G N + + I + F L D + DRE++ + D G+P ++S + + + DVNDN P F+ ++ E P GT VT V A D DE +S+L Y I TT F I S NG L+ Q LD + + GR S+ + IN+ D NN P+F + + +V ED P + ++ +D D GVNAQ+T ++ +++IN F I+ G + + A LDRE Y LT+ A DG P + + T V I + D+NDN+P F PL + V +I + D D G N + D I+ G F ID +++ N+ L E + L I D+G PP SS++E+QI ++D
Sbjct: 456 DCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQD----IGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQS---QFSIDSMSGDVSLVKPLDYESVR--SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE--SVLENVPVGYNIIRVQAYDSDEGANAEIT-YSISERDDNFPLAV-----DPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE--DSRLHYEI----TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGR---SDTATVHINITDANNFAPIFENAPYSASVFED-------APVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSL----SDTTDVEIGVTDVNDNAPAFKS--PLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDG----SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRLED 1105 HSP 2 Score: 178.718 bits (452), Expect = 5.014e-45 Identity = 173/580 (29.83%), Postives = 259/580 (44.66%), Query Frame = 2
Query: 377 DLNDNAPH-WPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFL----IGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF 2074
D NDNAP + + S+ EN +G A D D + ++ + F LA P Q K +DRE R ++ D G PP + + I + DVNDN P F+ Y ++ E+ Q V+A D D + +L Y+ + NT + FAI S NG I + +SLDY E + V A D G S + TV INI D N+ PI + ++FE+ + ++ VS D D G+N Q L I G F N I + DRE + T+T D G PSL+ + + + + DVNDN P F P SILE + +GT V +V A D D GLN ++ Y +SD + F + ++G + N+ LDR +F + + D G P LS+ +E+ I L D+N+ PP F VPE+ P +G I D D+GVNA + +I D+ N F + S L ++ LD E + + L+ +P ++ + I + D+NDN+P+ R+F
Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDN-FPLAVDPRTGWVQTIK-----PLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGED-QPPGTPVTTVTATDPDEDS--RLHYEITTGNT---RGRFAITSQNGRGLITIAQSLDYK--QEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPI--FENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAI---VTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKYLLSDRDIEDGSF--VIDPTSGTIRTNKGLDR-ESVAVFHLTAIAVDKGSPPLSSTVEVQIRLEDVNDSPPTFASDKITLYVPEN-------SPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSLVTRPGSERAQLLTMTELDYESTRK-RFELVVRAASPPLR----NDAHIEILVTDVNDNAPVL-RDF 1223 HSP 3 Score: 170.629 bits (431), Expect = 1.720e-42 Identity = 158/550 (28.73%), Postives = 253/550 (46.00%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP-PFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI---NKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSI 2215
+ L +D E+ LVI D GSP + + + ++D NDN P F T ++ S+ EN + + I V A D D G +++Y S+S D A++ G ++ IK LD + + ++F VVA D G P S+S++V+I + DVND P + N + + E+ P+ V+ D D+ + +G + QN LI D ++E T+ D G S T++ + + I D N+ P F S S+ E +P+GT V V A D D G+N+Q+ Y +++ P PF I G ++ N LDR + + V D G P+LS+ ++ I + D+N+ P F + ++ ED LV ++ +A SD D G+N ++ + D F I +G +++ LDRE + LT IA+D G+P + + T V I L D+ND+ P F + + V V + + D D G NAVV SI G + FS+
Sbjct: 641 VSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNI-IRVQAYDSDEGANAEITY--SISERDD-NFPLAVDPRTGWVQTIKPLDRE--EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDP--AFNPKYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITI----AQSLDYKQEKRFLLTVAATDSGGRSDTAT--VHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSG-YLLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDA-----LVGT--SVIQVAASDPDVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPL----SSTVEVQIRLEDVNDSPPTFASD-KITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIGGDDSNAFSL 1163 HSP 4 Score: 163.31 bits (412), Expect = 2.658e-40 Identity = 160/609 (26.27%), Postives = 270/609 (44.33%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRH-----FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN---NNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS-DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN---GMLQSVAVLDREEKEEYKLTLIAID--GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP----GIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+S+DRE D ++ TD PP +G + + +LD ND+ PTF ++ S+RE + S + I + A D D G ++ Y +V++ + + F I+S +G I SLD ++ + SY +V A D +++ +V + ++D ND P S + + + E+ + + + D DQG N +IG ++S D+ + + + D E I D G PS +++ + V ++D NDN P F S+LE+ P+G + +V+A D DEG N+++ Y IS+ R N FP + G + + LDR G F+ VV D G P S + I + D+N+ P FN + V ED P+ + +D D+ + + +F I+ G++ LD ++++ + LT+ A D G D T +V I + D N+ +PIF N P V V ++ + D D G NA + S+ G+ +P FSI+ ++ N L E + L V KD G P S + +++I + D
Sbjct: 420 ASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTV-ITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSD--SYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFS--ERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPL-----DYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISE-RDDN--FPLAVDPRTGWVQTIKPLDREEQGR-FAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVT-------TVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSGGRSD-------TATVHINITDANNFAPIFE-NAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGNPSLSDTTDVEIGVTD 999 HSP 5 Score: 93.5893 bits (231), Expect = 8.644e-19 Identity = 92/360 (25.56%), Postives = 156/360 (43.33%), Query Frame = 2
Query: 1373 DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-----------DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV-HFNES 2401
++ + P F S+LE P G VT VRA D ++ + + D R+ + F ++S G + + LDR L+D F V V +D P S + +N++D N+ P F F ++ E + ++ + +D D G NA++ I+ + F+I S +G++ + + LDRE + Y L + A D R T T SV + + D NDN P F R + + +A + D D G NA + +I G FSID V L + L E ++L++ +D G P +S++ ++ + + D+ +P+ F ES
Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPEDSPVVYSMVSLLDSRSQSL----FKVDSRTGVVTTSASLDRELMDVHYFRV--VATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIREGATVGSTVIT-------LRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQES 697
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 253.447 bits (646), Expect = 5.789e-70 Identity = 220/743 (29.61%), Postives = 363/743 (48.86%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF---HRNFP---LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPK---------------SSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLA--LGSFITIVIIKCRKKAK 2515
D+NDNAP + I +SI EN I + + +P A D D Q +K S F L + T + ++P+L ++ S+DRET D + I + D G+PP + I+ + + DVNDN P F + +++ EN + + + ++ A D D G+ ++ + S + S KRHFAI+ST G I + + LD + + +V+A D + S TVI+N+ D+ND +P I +N + + EN LN I ++V D D +NG+ C+ F L K +D + + A ++ +E +A I D G P L +S ++ + I D NDN+P F P SI E++ GT + K+ A D D G N+ +IY + P + F I+S +L V + LDR E +S V+ D+G L + + + + + D N+ P F ++F VPE+ LPL +G I V+D D G NA +TL+I + + F I G+++ DRE++ Y + A+D ++ T V I + D+NDN P+F N+ +P+ S V +F D D+G NA + SI G + F+ID+ ++ L K+ + QG+H+L+V KD G+P S++ IQ + S + + N+ + N +IV+ IA+I + L F+T +++CR+ +
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELVKSVSE-FGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-THLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNP--VHKLIVLASDGS--STPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRL--KPVFNDQFLLETAAPLDYETTRE-YAI-RIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLG-PDAPDG----FNIDSRSGILSVVKRLDR-EKQEKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPEN----LPLY---GTVGLITVTDADAGDNAVVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAG---LMQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPSNTSPGSVVTR----VFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFVNDTVSNATFIQEQLRKSLETPLERNIGDNDVTPQTNGYVIVV-IAIIAGTMTVILVIFVT-ALVRCRQTPR 841 HSP 2 Score: 135.576 bits (340), Expect = 7.125e-32 Identity = 151/540 (27.96%), Postives = 239/540 (44.26%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPT----FSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP----PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE--DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF---HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQS 2233
I D+NDN P F + IS+ EN +NS P+ SA D D G G Y+ S ++ + +LI D + ++ + D G P SS+ + + + DVND P+ S ++ + EN + + + D D G N Q + F ++ + D + K DRE + D S S + V + D+NDN+P+ + M + ++L E++P+ T + + D+D LN ++ + +D ++ P FL+E+ L + +++ +V SD G+P L+ + I + D N+ PVF Q ++PE DP L I+ +D D G NA + ++ D + F I S +G+L V LDRE++E+Y T+IA D GT +Q TV + + D NDNSP F NF +P + Y LI V D D+G NAVV LSI K G+I P + DR++QS
Sbjct: 129 IEDINDNAPLFQSTVINISIPENTAINSRYPVP-SAFDPDIGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPV--FKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIH-FSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGS--STPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCY-TDHDVPFRLKPVFNDQFLLETAAPLDYETTRE-------YAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLI---------KISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVK----LIVQDQNDNSPAFTHPEYNFYVPENLPL--YGTVGLIT--VTDADAGDNAVVTLSIINGKDNFIIDPKTGVIKPNITFDREQQS 637 HSP 3 Score: 85.5001 bits (210), Expect = 2.445e-16 Identity = 101/404 (25.00%), Postives = 168/404 (41.58%), Query Frame = 2
Query: 1253 LMAKHKFDREKEAFAYTTITCCDYGIP-SLTSSQL-----ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDG--TPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIK---PGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
L ++ DREK C Y I ++ ++ I +I D+NDN P F + SI E++ I + A D D G+N I H ++ ++ + G+ L+V Q LDR + F + + V D G P S+ + + + D+N+ PVF S VPE+ P ++ ++ +D D G NAQ+ + + I+ H G++ LDRE +KL ++A DG TP +V++ + D+NDN P + N PL TK++ + V D+DS N V P + P F+ D+ ++ L E + + ++ D G+PP ++S + I I D
Sbjct: 85 LTTANRIDREKLCSGVFNEKRCYYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGING--IQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETK-DTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPEN-------APMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTPS-------RATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIAL----------ITVTDRDSDLNGKVTCYTDHDVPFRLKPVFN---DQFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKD 458
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 253.832 bits (647), Expect = 8.346e-70 Identity = 220/743 (29.61%), Postives = 363/743 (48.86%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF---HRNFP---LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPK---------------SSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLA--LGSFITIVIIKCRKKAK 2515
D+NDNAP + I +SI EN I + + +P A D D Q +K S F L + T + ++P+L ++ S+DRET D + I + D G+PP + I+ + + DVNDN P F + +++ EN + + + ++ A D D G+ ++ + S + S KRHFAI+ST G I + + LD + + +V+A D + S TVI+N+ D+ND +P I +N + + EN LN I ++V D D +NG+ C+ F L K +D + + A ++ +E +A I D G P L +S ++ + I D NDN+P F P SI E++ GT + K+ A D D G N+ +IY + P + F I+S +L V + LDR E +S V+ D+G L + + + + + D N+ P F ++F VPE+ LPL +G I V+D D G NA +TL+I + + F I G+++ DRE++ Y + A+D ++ T V I + D+NDN P+F N+ +P+ S V +F D D+G NA + SI G + F+ID+ ++ L K+ + QG+H+L+V KD G+P S++ IQ + S + + N+ + N +IV+ IA+I + L F+T +++CR+ +
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGINGIQHYELVKSVSE-FGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-THLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNP--VHKLIVLASDGS--STPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCYTDHDVPFRL--KPVFNDQFLLETAAPLDYETTRE-YAI-RIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQLIKISATDADSGSNALIIYSLG-PDAPDG----FNIDSRSGILSVVKRLDREKQ-EKYSFTVIARDNGTTPLQSNVTVKLIVQDQNDNSPAFTHPEYNFYVPEN----LPLY---GTVGLITVTDADAGDNAVVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDAG---LMQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVPSNTSPGSVVTR----VFAIDNDTGMNAELQYSIIGGSLRGLFTIDKTTGNITLQEKIVAADQGLHRLVVKVKDLGQPESLHAIALVHLFVNDTVSNATFIQEQLRKSLETPLERNIGDNDVTPQTNGYVIVV-IAIIAGTMTVILVIFVT-ALVRCRQTPR 841 HSP 2 Score: 135.576 bits (340), Expect = 7.251e-32 Identity = 151/540 (27.96%), Postives = 239/540 (44.26%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPT----FSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP----PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE--DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF---HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQS 2233
I D+NDN P F + IS+ EN +NS P+ SA D D G G Y+ S ++ + +LI D + ++ + D G P SS+ + + + DVND P+ S ++ + EN + + + D D G N Q + F ++ + D + K DRE + D S S + V + D+NDN+P+ + M + ++L E++P+ T + + D+D LN ++ + +D ++ P FL+E+ L + +++ +V SD G+P L+ + I + D N+ PVF Q ++PE DP L I+ +D D G NA + ++ D + F I S +G+L V LDRE++E+Y T+IA D GT +Q TV + + D NDNSP F NF +P + Y LI V D D+G NAVV LSI K G+I P + DR++QS
Sbjct: 129 IEDINDNAPLFQSTVINISIPENTAINSRYPVP-SAFDPDIGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPV--FKDSEVEVNVPENAPMGTSVTHLHATDADLGSNAQIH-FSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGS--STPSRATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIALITVTDRDSDLNGKVTCY-TDHDVPFRLKPVFNDQFLLETAAPLDYETTRE-------YAIRIVASDSGKPPLNTSAMVLIKIKDENDNVPVFPQPEIQLSIPENNDPGTQL---------IKISATDADSGSNALIIYSLGPDAPDGFNIDSRSGILSVVKRLDREKQEKYSFTVIARDNGTTPLQSNVTVK----LIVQDQNDNSPAFTHPEYNFYVPENLPL--YGTVGLIT--VTDADAGDNAVVTLSIINGKDNFIIDPKTGVIKPNITFDREQQS 637 HSP 3 Score: 85.1149 bits (209), Expect = 3.296e-16 Identity = 101/404 (25.00%), Postives = 168/404 (41.58%), Query Frame = 2
Query: 1253 LMAKHKFDREKEAFAYTTITCCDYGIP-SLTSSQL-----ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDG--TPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIK---PGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
L ++ DREK C Y I ++ ++ I +I D+NDN P F + SI E++ I + A D D G+N I H ++ ++ + G+ L+V Q LDR + F + + V D G P S+ + + + D+N+ PVF S VPE+ P ++ ++ +D D G NAQ+ + + I+ H G++ LDRE +KL ++A DG TP +V++ + D+NDN P + N PL TK++ + V D+DS N V P + P F+ D+ ++ L E + + ++ D G+PP ++S + I I D
Sbjct: 85 LTTANRIDREKLCSGVFNEKRCYYEIEVAVLPDEIFRLVKIRFLIEDINDNAPLFQSTVINISIPENTAINSRYPVPSAFDPDIGING--IQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQSLDRETK-DTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPEN-------APMGTSVTHLHATDADLGSNAQIHFSFSNQISPSTKRHFAIDSTTGLITVKQPLDREVNPVHKLIVLASDGSSTPS-------RATVIVNVTDINDNVPSIDTRYIMNLVNGTVLLSENAPLNTKIAL----------ITVTDRDSDLNGKVTCYTDHDVPFRLKPVFN---DQFLLETAAPLDYETTREYAIRIVASDSGKPPLNTSAMVLIKIKD 458
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh7b (protocadherin 7b [Source:ZFIN;Acc:ZDB-GENE-081104-299]) HSP 1 Score: 251.906 bits (642), Expect = 2.745e-69 Identity = 228/777 (29.34%), Postives = 355/777 (45.69%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-------------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLI---IYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFP-------LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD------------SQPLS-PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP + TVIINI D ND +P I + K LKD + E+ ++ PI V V D D+G NG C ++G F L + + Y L D E I D G PSL+S+ + V + D+NDN P FS S E++ G V V ALD D G N+++ Y + + N +F + G++ VN LDR E + V+ D G P L + + + D N+ P F Q F F + E+ + P +G I V D DKG NA ++L I++ N F I +N G + S DRE++ Y + A+DG + T +V + + D+NDN P FP LP + + VR + D D+G NA + I G F +D + L KL+ +H G+H+L+V D G P +S++ + I +++ ++ LS P N + + K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 129 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPI-LQLKAGDTDVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREDVSQL--RFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVTVVALDADSGKNAEISYSLDS--SVNGIFS--IDADTGDIRVNTILDR-EQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSP-------VGMITVMDADKGQNADMSLYIEEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGG---DPPRSATATVSLSVMDVNDNPPTVL--FPMNNSYTLLPPSSNIRTVVR----TVSATDTDTGVNANLSYRIVGGNPFKLFDMDAWTGVISLVGKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHIYVNETLFNSTIVEAQVAKSLSTPLNADIAGDPNYDLGKQRLSIAIGVVSGIMTVILIILVVVMARYCRPKNK 880 HSP 2 Score: 139.428 bits (350), Expect = 4.971e-33 Identity = 163/623 (26.16%), Postives = 271/623 (43.50%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFA------INSTNGEIRLIKSLDYDSGNEL--------------------------SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVN-QHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELI------ALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N +S R ++S +G+ R + S EL SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE + T+ D G P T + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E + N H LD E ++V++V D G P+LS+ + + + D+N+ PPVF++ST + PE+ + P R + +A+ D D G NA+++ ++ ++N F I + G ++ +LDRE+ E Y+ +IA D G P +Q + +VV+ + D NDN P F ++ + Y++ L + V D D G NA + L I+ FSID + ++ N E + + V D G PP+S++ + +++ D P + N S
Sbjct: 127 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTP--RFEKSVYEADLPENSSPGAPILQLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVG-DVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNA------PGERVVTVVAL-DADSGKNAEISYSLDSSVNGIFSIDADTGDIRVNTILDREQTERYEFKVIAKDKGMPVLQ----GSATVVVLVADKNDNEPKFMQDV-------FTFYIQENLQPNSPVGMITVMDADKGQNADMSLYIEEE--ENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGGDPPRSATATVSLSVMDVNDNPPTVLFPMNNS 720 HSP 3 Score: 73.9442 bits (180), Expect = 8.760e-13 Identity = 79/323 (24.46%), Postives = 133/323 (41.18%), Query Frame = 2
Query: 1361 VIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI-------------------SDPRTTNQMFPPFLI---------------ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL---AIKDNINKFQI--SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSP---------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI 2182
VII+D+NDN P+F P + S+ E+ PIGT+ A D+D G N Y + D + + F E L++ LDR + + + + V D G P S+Q + + + D+N+ P F +S + +PE+ S P++ + D D GVN Q+ A +++ + G L + +DRE+ + + T++A D G P T +V+I + D NDN P IF ++ V+ V + + V D+D G N +V ++
Sbjct: 125 VIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDR-EQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPIL-------QLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVLHRIDREDVSQLRFTVMARDRGQPP----KTDKATVIINIKDENDNVPNIDIRKIGRIFLKDG--VANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTV 433
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh7b (protocadherin 7b [Source:ZFIN;Acc:ZDB-GENE-081104-299]) HSP 1 Score: 252.292 bits (643), Expect = 3.128e-69 Identity = 228/777 (29.34%), Postives = 355/777 (45.69%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-------------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLI---IYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFP-------LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD------------SQPLS-PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP + TVIINI D ND +P I + K LKD + E+ ++ PI V V D D+G NG C ++G F L + + Y L D E I D G PSL+S+ + V + D+NDN P FS S E++ G V V ALD D G N+++ Y + + N +F + G++ VN LDR E + V+ D G P L + + + D N+ P F Q F F + E+ + P +G I V D DKG NA ++L I++ N F I +N G + S DRE++ Y + A+DG + T +V + + D+NDN P FP LP + + VR + D D+G NA + I G F +D + L KL+ +H G+H+L+V D G P +S++ + I +++ ++ LS P N + + K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 129 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPI-LQLKAGDTDVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREDVSQL--RFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVTVVALDADSGKNAEISYSLDS--SVNGIFS--IDADTGDIRVNTILDR-EQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSP-------VGMITVMDADKGQNADMSLYIEEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGG---DPPRSATATVSLSVMDVNDNPPTVL--FPMNNSYTLLPPSSNIRTVVR----TVSATDTDTGVNANLSYRIVGGNPFKLFDMDAWTGVISLVGKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHIYVNETLFNSTIVEAQVAKSLSTPLNADIAGDPNYDLGKQRLSIAIGVVSGIMTVILIILVVVMARYCRPKNK 880 HSP 2 Score: 139.428 bits (350), Expect = 4.636e-33 Identity = 163/623 (26.16%), Postives = 271/623 (43.50%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFA------INSTNGEIRLIKSLDYDSGNEL--------------------------SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVN-QHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA------LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N +S R ++S +G+ R + S EL SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE + T+ D G P T + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E + N H LD E ++V++V D G P+LS+ + + + D+N+ PPVF++ST + PE+ + P R + +A+ D D G NA+++ ++ ++N F I + G ++ +LDRE+ E Y+ +IA D G P +Q + +VV+ + D NDN P F ++ + Y++ L + V D D G NA + L I+ FSID + ++ N E + + V D G PP+S++ + +++ D P + N S
Sbjct: 127 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTP--RFEKSVYEADLPENSSPGAPILQLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVG-DVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNA------PGERVVTVVAL-DADSGKNAEISYSLDSSVNGIFSIDADTGDIRVNTILDREQTERYEFKVIAKDKGMPVLQ----GSATVVVLVADKNDNEPKFMQDV-------FTFYIQENLQPNSPVGMITVMDADKGQNADMSLYIEEE--ENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGGDPPRSATATVSLSVMDVNDNPPTVLFPMNNS 720 HSP 3 Score: 73.9442 bits (180), Expect = 8.874e-13 Identity = 79/323 (24.46%), Postives = 133/323 (41.18%), Query Frame = 2
Query: 1361 VIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI-------------------SDPRTTNQMFPPFLI---------------ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL---AIKDNINKFQI--SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSP---------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI 2182
VII+D+NDN P+F P + S+ E+ PIGT+ A D+D G N Y + D + + F E L++ LDR + + + + V D G P S+Q + + + D+N+ P F +S + +PE+ S P++ + D D GVN Q+ A +++ + G L + +DRE+ + + T++A D G P T +V+I + D NDN P IF ++ V+ V + + V D+D G N +V ++
Sbjct: 125 VIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDR-EQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPIL-------QLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVLHRIDREDVSQLRFTVMARDRGQPP----KTDKATVIINIKDENDNVPNIDIRKIGRIFLKDG--VANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTV 433
BLAST of Protocadherin vs. Ensembl Zebrafish
Match: pcdh7b (protocadherin 7b [Source:ZFIN;Acc:ZDB-GENE-081104-299]) HSP 1 Score: 253.062 bits (645), Expect = 3.734e-69 Identity = 228/777 (29.34%), Postives = 355/777 (45.69%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-------------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLI---IYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFP-------LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD------------SQPLS-PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP + TVIINI D ND +P I + K LKD + E+ ++ PI V V D D+G NG C ++G F L + + Y L D E I D G PSL+S+ + V + D+NDN P FS S E++ G V V ALD D G N+++ Y + + N +F + G++ VN LDR E + V+ D G P L + + + D N+ P F Q F F + E+ + P +G I V D DKG NA ++L I++ N F I +N G + S DRE++ Y + A+DG + T +V + + D+NDN P FP LP + + VR + D D+G NA + I G F +D + L KL+ +H G+H+L+V D G P +S++ + I +++ ++ LS P N + + K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 129 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPI-LQLKAGDTDVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREDVSQL--RFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVGDVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNAPGERVVTVVALDADSGKNAEISYSLDS--SVNGIFS--IDADTGDIRVNTILDR-EQTERYEFKVIAKDKGMPVLQGSATVVVLVADKNDNEPKFMQDVFTFYIQENLQPNSP-------VGMITVMDADKGQNADMSLYIEEEENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGG---DPPRSATATVSLSVMDVNDNPPTVL--FPMNNSYTLLPPSSNIRTVVR----TVSATDTDTGVNANLSYRIVGGNPFKLFDMDAWTGVISLVGKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHIYVNETLFNSTIVEAQVAKSLSTPLNADIAGDPNYDLGKQRLSIAIGVVSGIMTVILIILVVVMARYCRPKNK 880 HSP 2 Score: 140.198 bits (352), Expect = 3.544e-33 Identity = 161/608 (26.48%), Postives = 266/608 (43.75%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFA------INSTNGEIRLIKSLDYDSGNEL--------------------------SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVN-QHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA------LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N +S R ++S +G+ R + S EL SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE + T+ D G P T + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E + N H LD E ++V++V D G P+LS+ + + + D+N+ PPVF++ST + PE+ + P R + +A+ D D G NA+++ ++ ++N F I + G ++ +LDRE+ E Y+ +IA D G P +Q T VV+ + D NDN P F ++ + Y++ L + V D D G NA + L I+ FSID + ++ N E + + V D G PP+S++ + +++ D
Sbjct: 127 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTP--RFEKSVYEADLPENSSPGAPILQLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREDVSQLRFTVMARDRGQPPKTDKATVIINIKDENDNVPNIDIRKIGRIFLKDGVANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTVVG-DVPFQLKPASEVEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDMNDNPPVFSKSTVEVSFPENNA------PGERVVTVVAL-DADSGKNAEISYSLDSSVNGIFSIDADTGDIRVNTILDREQTERYEFKVIAKDKGMPVLQGSAT----VVVLVADKNDNEPKFMQDV-------FTFYIQENLQPNSPVGMITVMDADKGQNADMSLYIEEE--ENIFSIDNNTGTIFSNMAFDREQRNNYSFRVKAVDGGDPPRSATATVSLSVMD 705 HSP 3 Score: 74.3294 bits (181), Expect = 6.107e-13 Identity = 79/323 (24.46%), Postives = 133/323 (41.18%), Query Frame = 2
Query: 1361 VIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI-------------------SDPRTTNQMFPPFLI---------------ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL---AIKDNINKFQI--SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSP---------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI 2182
VII+D+NDN P+F P + S+ E+ PIGT+ A D+D G N Y + D + + F E L++ LDR + + + + V D G P S+Q + + + D+N+ P F +S + +PE+ S P++ + D D GVN Q+ A +++ + G L + +DRE+ + + T++A D G P T +V+I + D NDN P IF ++ V+ V + + V D+D G N +V ++
Sbjct: 125 VIILDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGESTVRRIGTSGSGSVDSHSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDR-EQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNTPRFEKSVYEADLPENSSPGAPIL-------QLKAGDTDVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVLHRIDREDVSQLRFTVMARDRGQPP----KTDKATVIINIKDENDNVPNIDIRKIGRIFLKDG--VANVAEDVIVDTPIALVQVSDRDKGPNGIVTCTV 433
BLAST of Protocadherin vs. Ensembl Xenopus
Match: emc7 (ER membrane protein complex subunit 7 [Source:Xenbase;Acc:XB-GENE-945123]) HSP 1 Score: 265.388 bits (677), Expect = 9.103e-74 Identity = 225/777 (28.96%), Postives = 366/777 (47.10%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-----------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL------FKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTK---VSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ L++ EN +GTL+ +P A D D + + + +SS F+L T D + P+L +K +DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ +G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P+I + K +KD + E+ ++ PI V V D DQG NG C ++G F L +QN Y L D E I D G PSL+S+ + V + D NDN P FS + E++ +G V V A D D G N+++ Y + +P M F I + G++ VN LDR + + V+ D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I+++ + F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P +FP+ + +S VR + ++ D D+G NA ++ SI G F ID V L KL S+H G+H+L+V D G+PP+S+ + + ++++ +S +V + ++ ++K+ + I I V+ ++ + I +V++ CR K+K
Sbjct: 131 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELIQDAGESLYVSGRRGAAESSLYPGKRRMESDSRSSVFELQVADTSDGEKQPQLIVKGPLDREQRDSYELTLRVRDGGEPPRSSQSILRVLITDVNDNNPRFEKSVYEADLAENSAPGTPI-LQLRATDYDVGVNGQIEYVFGAA-TESVRRLLRLDENSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPLIDIRKIGRIPVKDGMANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPANDGEGEQNKKK---YFLHTSAPLDYENVKEYNVIIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFSQAVVEVAFPENNVLGERVATVLATDADSGKNAEIAYSL-EP----SMEGIFSIHPDTGDITVNIILDR-EQTDRYEFKVIAKDKGIPVLQGTTSVVVQVADRNDNEPRFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLFIEEDSDIFSIENDTGTIYSTVSFDREHQTSYTFKVKAVDGG---DPPRSATATVSLFVMDENDNAPTI--SFPINSSYAVLSPSSNVRTVVASVVATDSDNGVNADLNYSIVGGNPYKLFEIDSTSGVVSLVGKLTSKHYGLHRLVVQVNDSGQPPQSTIALVHVFVNET--ISNATVVDYQIARSLHTPLTQDIAGDPSYDMSKQRLSIVIGVVAGIMTVILIILVVVMARYCRAKSK 880
BLAST of Protocadherin vs. Ensembl Xenopus
Match: emc7 (ER membrane protein complex subunit 7 [Source:Xenbase;Acc:XB-GENE-945123]) HSP 1 Score: 264.618 bits (675), Expect = 1.656e-73 Identity = 225/777 (28.96%), Postives = 366/777 (47.10%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-----------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL------FKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTK---VSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ L++ EN +GTL+ +P A D D + + + +SS F+L T D + P+L +K +DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ +G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P+I + K +KD + E+ ++ PI V V D DQG NG C ++G F L +QN Y L D E I D G PSL+S+ + V + D NDN P FS + E++ +G V V A D D G N+++ Y + +P M F I + G++ VN LDR + + V+ D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I+++ + F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P +FP+ + +S VR + ++ D D+G NA ++ SI G F ID V L KL S+H G+H+L+V D G+PP+S+ + + ++++ +S +V + ++ ++K+ + I I V+ ++ + I +V++ CR K+K
Sbjct: 131 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELIQDAGESLYVSGRRGAAESSLYPGKRRMESDSRSSVFELQVADTSDGEKQPQLIVKGPLDREQRDSYELTLRVRDGGEPPRSSQSILRVLITDVNDNNPRFEKSVYEADLAENSAPGTPI-LQLRATDYDVGVNGQIEYVFGAA-TESVRRLLRLDENSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPLIDIRKIGRIPVKDGMANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPANDGEGEQNKKK---YFLHTSAPLDYENVKEYNVIIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFSQAVVEVAFPENNVLGERVATVLATDADSGKNAEIAYSL-EP----SMEGIFSIHPDTGDITVNIILDR-EQTDRYEFKVIAKDKGIPVLQGTTSVVVQVADRNDNEPRFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLFIEEDSDIFSIENDTGTIYSTVSFDREHQTSYTFKVKAVDGG---DPPRSATATVSLFVMDENDNAPTI--SFPINSSYAVLSPSSNVRTVVASVVATDSDNGVNADLNYSIVGGNPYKLFEIDSTSGVVSLVGKLTSKHYGLHRLVVQVNDSGQPPQSTIALVHVFVNET--ISNATVVDYQIARSLHTPLTQDIAGDPSYDMSKQRLSIVIGVVAGIMTVILIILVVVMARYCRAKSK 880
BLAST of Protocadherin vs. Ensembl Xenopus
Match: emc7 (ER membrane protein complex subunit 7 [Source:Xenbase;Acc:XB-GENE-945123]) HSP 1 Score: 264.233 bits (674), Expect = 2.043e-73 Identity = 225/777 (28.96%), Postives = 366/777 (47.10%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-----------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL------FKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTK---VSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ L++ EN +GTL+ +P A D D + + + +SS F+L T D + P+L +K +DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ +G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P+I + K +KD + E+ ++ PI V V D DQG NG C ++G F L +QN Y L D E I D G PSL+S+ + V + D NDN P FS + E++ +G V V A D D G N+++ Y + +P M F I + G++ VN LDR + + V+ D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I+++ + F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P +FP+ + +S VR + ++ D D+G NA ++ SI G F ID V L KL S+H G+H+L+V D G+PP+S+ + + ++++ +S +V + ++ ++K+ + I I V+ ++ + I +V++ CR K+K
Sbjct: 131 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELIQDAGESLYVSGRRGAAESSLYPGKRRMESDSRSSVFELQVADTSDGEKQPQLIVKGPLDREQRDSYELTLRVRDGGEPPRSSQSILRVLITDVNDNNPRFEKSVYEADLAENSAPGTPI-LQLRATDYDVGVNGQIEYVFGAA-TESVRRLLRLDENSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPLIDIRKIGRIPVKDGMANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPANDGEGEQNKKK---YFLHTSAPLDYENVKEYNVIIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFSQAVVEVAFPENNVLGERVATVLATDADSGKNAEIAYSL-EP----SMEGIFSIHPDTGDITVNIILDR-EQTDRYEFKVIAKDKGIPVLQGTTSVVVQVADRNDNEPRFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLFIEEDSDIFSIENDTGTIYSTVSFDREHQTSYTFKVKAVDGG---DPPRSATATVSLFVMDENDNAPTI--SFPINSSYAVLSPSSNVRTVVASVVATDSDNGVNADLNYSIVGGNPYKLFEIDSTSGVVSLVGKLTSKHYGLHRLVVQVNDSGQPPQSTIALVHVFVNET--ISNATVVDYQIARSLHTPLTQDIAGDPSYDMSKQRLSIVIGVVAGIMTVILIILVVVMARYCRAKSK 880
BLAST of Protocadherin vs. Ensembl Xenopus
Match: emc7 (ER membrane protein complex subunit 7 [Source:Xenbase;Acc:XB-GENE-945123]) HSP 1 Score: 264.233 bits (674), Expect = 2.462e-73 Identity = 225/777 (28.96%), Postives = 366/777 (47.10%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD-----------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL------FKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTK---VSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ L++ EN +GTL+ +P A D D + + + +SS F+L T D + P+L +K +DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ +G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P+I + K +KD + E+ ++ PI V V D DQG NG C ++G F L +QN Y L D E I D G PSL+S+ + V + D NDN P FS + E++ +G V V A D D G N+++ Y + +P M F I + G++ VN LDR + + V+ D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I+++ + F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P +FP+ + +S VR + ++ D D+G NA ++ SI G F ID V L KL S+H G+H+L+V D G+PP+S+ + + ++++ +S +V + ++ ++K+ + I I V+ ++ + I +V++ CR K+K
Sbjct: 131 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELIQDAGESLYVSGRRGAAESSLYPGKRRMESDSRSSVFELQVADTSDGEKQPQLIVKGPLDREQRDSYELTLRVRDGGEPPRSSQSILRVLITDVNDNNPRFEKSVYEADLAENSAPGTPI-LQLRATDYDVGVNGQIEYVFGAA-TESVRRLLRLDENSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPLIDIRKIGRIPVKDGMANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPANDGEGEQNKKK---YFLHTSAPLDYENVKEYNVIIVAVDSGSPSLSSNNSLIVKVGDTNDNPPVFSQAVVEVAFPENNVLGERVATVLATDADSGKNAEIAYSL-EP----SMEGIFSIHPDTGDITVNIILDR-EQTDRYEFKVIAKDKGIPVLQGTTSVVVQVADRNDNEPRFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLFIEEDSDIFSIENDTGTIYSTVSFDREHQTSYTFKVKAVDGG---DPPRSATATVSLFVMDENDNAPTI--SFPINSSYAVLSPSSNVRTVVASVVATDSDNGVNADLNYSIVGGNPYKLFEIDSTSGVVSLVGKLTSKHYGLHRLVVQVNDSGQPPQSTIALVHVFVNET--ISNATVVDYQIARSLHTPLTQDIAGDPSYDMSKQRLSIVIGVVAGIMTVILIILVVVMARYCRAKSK 880
BLAST of Protocadherin vs. Ensembl Xenopus
Match: pcdh17 (protocadherin 17 [Source:Xenbase;Acc:XB-GENE-480220]) HSP 1 Score: 245.743 bits (626), Expect = 5.241e-67 Identity = 236/799 (29.54%), Postives = 360/799 (45.06%), Query Frame = 2
Query: 65 FIFSMSIIDRDS-ITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRL-SSSGII-----SVARQ--LDCDN--DSNLCDKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDIT-------IFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDL-----IIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE------LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
F + I+ + + V E P N + L + P +S + + H Y R+ +G I S+ R+ +C N C E MT L + ++ I I+ D+NDN P++ P I LSI EN IG LF IP A D D I + F L DE Q P+L + +DRE D +L I + D G+P ++ I ILD NDN P F Y L EN + + + V A D D G ++ Y H S D+V+R ++ + G I + +D + L +S VVA D G ++ T V I I D ND P+I + + +T I E+ + P+ V V D+D+G+N C + G F L + +SD Y L D E I D G P L+S+ + V + DVNDN P FS E++ I +V +V A D D G NSQL Y I + +F + +G + VN LDR E + VV D G P+L + I ++D N+ P F + ++F+V E+ +P+ +G + V D DKG NA + L+++ +F I + G + S DRE + Y L A+DG R + G V I + D NDN+P+ +P+ +SYK Y+ + + + ED D+G NA +D SI G F I + V L + + +H G+H+L+V D+G+P + + + I+++
Sbjct: 56 LFFQLPILGSSTKVAYRVPEEQPPNILIGSLASDYGYP-DSKHLYKLELGHPYLRVDGKTGDIYTTETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDGQIEIM--DINDNTPNFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQ-PQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSV-LQVKANDSDQGVNAEIDYSFHQAS--DTVRRLLHLDRSTGLITVQGPIDREDVGTLKFS--VVAKDKGANPKTARTQVTITIRDTNDNKPVIEI-RGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQL---KQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFS--INPDSGQIRVNTVLDR-EQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLNGYNFSVMEN-------MPRLSPVGMVTVIDADKGENAHIHLSVEPESGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGD--PPRSSYVG-VTINVLDENDNAPV----IVVPSNISYK-YLTPQTHPGTPVNWVRAEDMDTGINAELDYSIASGNPFELFQISHNNGEVTLEKAIIRKHYGLHRLVVKVTDKGKPSRHGTALVHFYINET 823 HSP 2 Score: 155.606 bits (392), Expect = 6.453e-38 Identity = 170/639 (26.60%), Postives = 278/639 (43.51%), Query Frame = 2
Query: 596 KSSIDRETNDR-----------IELVILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVS--NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHS----------PIGTVVTKVRALDKDEGLNSQL-----------IYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI----SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
++SIDRE+ +E + +TD SP P +G I+I+D+NDN P F++ +S+ EN + L PI +A D DSG G SY+ V D A + + +LI D SY + D G PA +SS + I+I+D ND P K + + EN+ + ++ V +D DQG+N + + H+ D + + D + + DRE ++ D G T+ +T+ I D NDN P + F ++ H P+ T V V+ D DEG+N+ + + +SD T + + +++ L + +++ +V D G P LS+ + + + D+N+ PVF+QS PE+ +D LV + ++ +D D G N+QL +I + + I +G ++ VLDRE++E Y ++A+D G P ++ T SVVI + D NDN P F N Y V + L V D D G NA + LS++P + F I ++ + EHQ + + D G PP+SS + + I + D +P
Sbjct: 121 ETSIDRESLRECQNLEPGEKCFLEFEVSMTDLMSPVPRLLDG--QIEIMDINDNTPNFNSPVITLSIPENTNIGMLFPI-PAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAP--KFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSF--HQASDTVRRLLHLDRSTGLITVQGPIDREDVGTLKFSVVAKDKGANPKTARTQVTITIRDTNDNKPVIEI--RGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSD--TGSDSKKKYFLQTTTALDYESVKE-------YTIEIVAVDSGNPPLSSTNSLKVQVTDVNDNAPVFSQSLMEVVFPEN-NDINDLVME------VSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLK----GTASVVITVLDRNDNDPKFMLN-------GYNFSVMENMPRLSPVGMVTVIDADKGENAHIHLSVEPE--SGEFVIQNGTGTILSSISFDREHQSTYTFRLKAVDGGDPPRSSYVGVTINVLDENDNAP 721 HSP 3 Score: 145.206 bits (365), Expect = 9.764e-35 Identity = 138/472 (29.24%), Postives = 223/472 (47.25%), Query Frame = 2
Query: 1028 INIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQ--LMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI-FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPL-VPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI--NKFQISHNG-------MLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEY--VRHELIALFVEDKDSGANAVVDLSIKPGIIA-PYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVH 2389
I I+D+ND P + N + ++I EN N+ + D D G+NG + LI G + DL Q D Q L+ DRE+ TI D G P+ SS L+ + I+D NDN P F A + E+SP+G V +V+A D D+G+N+++ Y T + L S G + V +DR G + FS VV D G + + ++TI + D N+ PV F + ++ VP + + VSD D+GVNA +T + ++ Q+S G LQ+ LD E +EY + ++A+D G P + + T S+ + + D+NDN+P+F ++ +V + E + ++ + D DSG N+ + SI P A FSI+ D +++N L E + + V+ D+G P + + IT+ D PK M++
Sbjct: 164 IEIMDINDNTP--NFNSPVITLSIPENTNIGMLFPIPAATDRDSGVNGVSSYELIVGPEAQDLFGLQVAEDQDEKQPQLIVMGMLDREQRDSYDLTIKVQDGGTPARASSALLRISILDTNDNAPKFEKMAYEAELPENSPMGHSVLQVKANDSDQGVNAEIDYSFHQASDTVRRL-LHLDRSTGLITVQGPIDREDVGTLKFS--VVAKDKGANPKTARTQVTITIRDTNDNKPVIEIRGFGLVTHQGGVANISEDVPVETPVALVQVSDIDEGVNAAVTCVVAGDVPFQLKQVSDTGSDSKKKYFLQTTTALDYESVKEYTIEIVAVDSGNPPL----SSTNSLKVQVTDVNDNAPVFSQSL---MEVVFPENNDINDLVMEVSATDADSGPNSQLHYSILPDPSARGIFSINPDSGQIRVNTVLDREQREHYDFHVVAVDKGIPSLKGTASVVITVLDRNDNDPKFMLN 623
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh7 (protocadherin 7 [Source:MGI Symbol;Acc:MGI:1860487]) HSP 1 Score: 254.603 bits (649), Expect = 4.372e-70 Identity = 212/693 (30.59%), Postives = 327/693 (47.19%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQI---------TIDDSQPL----SPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + T+ DSQ + +P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRATDLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREFNVVIVAVDSGSPSLSSNNSLVVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGTFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDSTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATVIDSQIVRSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVMMARYCRSKNK 909
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh7 (protocadherin 7 [Source:MGI Symbol;Acc:MGI:1860487]) HSP 1 Score: 254.988 bits (650), Expect = 9.197e-70 Identity = 212/693 (30.59%), Postives = 327/693 (47.19%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQI---------TIDDSQPL----SPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + T+ DSQ + +P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRATDLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREFNVVIVAVDSGSPSLSSNNSLVVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGTFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDSTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATVIDSQIVRSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVMMARYCRSKNK 909
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh7 (protocadherin 7 [Source:MGI Symbol;Acc:MGI:1860487]) HSP 1 Score: 254.603 bits (649), Expect = 1.042e-69 Identity = 212/693 (30.59%), Postives = 327/693 (47.19%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQI---------TIDDSQPL----SPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + T+ DSQ + +P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRATDLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSAPLDYETTREFNVVIVAVDSGSPSLSSNNSLVVKVGDTNDNPPVFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGTFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENSNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPRNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDSTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATVIDSQIVRSLHTPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVMMARYCRSKNK 909
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 250.366 bits (638), Expect = 8.471e-69 Identity = 200/679 (29.46%), Postives = 320/679 (47.13%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN-NNLNEPIVD------VSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSD-LIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFV-----EDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P++ P I L+I EN IG+LF IP A D D + F L + D E + P+L + ++DRE D +L I + D G+PP ++ + +LD NDN P F Y L EN + + I V A D D G ++ Y + + V+R ++ G I + +D + + L +S V+A D G S+ V++ + D+ND P I + + + +T + N++E + + V V D D+G N C + G F L + SD Y L D EK I D G P L+S+ + V +VDVNDN P F+ T + E++ G VV +V A D D G N++L+Y + +F + NG + V LDR + + + VV +D G P+L + +N++D N+ P F S ++F+V E+ +P +G + V D DKG NA++ L+++ + F I + G + S DRE++ Y L A+DG V R G V I + D NDN+P P+ S++ + V ED DSG NA + SI G F I ++ L ++++ H G+H+L+V DRG+PP+ + + + ++++
Sbjct: 138 DINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQ-VAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSV-IQVKANDSDQGANAEIDYTFHQA-PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS--VLAKDRGATPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLF--TISPENGEIRVKTSLDR-EQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMEN-------MPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG--GVPPRSAYVG-VTINVLDENDNAPFIT----APSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET 793 HSP 2 Score: 146.362 bits (368), Expect = 3.657e-35 Identity = 159/637 (24.96%), Postives = 272/637 (42.70%), Query Frame = 2
Query: 629 IELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVS--NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD---------PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINK---FQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL--SPKNMVH 2389
+E + +TD +GSP L EG I +Q D+NDN P F++ +++ EN + SL PI + A D D+G G SY+ + A + + +LI + D SY + D G P +SS + + ++D ND P + + + EN+ + ++ V +D DQG N + + H+ +++ + D + + DRE + ++ D G ++ + V + D+NDN PT + +I E T V V+ D+DEG N+ + ++ T + + +++ L + D +++ +V D G P LS+ + + ++D+N+ PVF QS PE+ KP + + SD D G NA+L +++ F IS NG ++ LDRE+++ Y+L ++A D G+P +Q T +V++ + D NDN P F + Y V + AL V D D G NA V LS++ G I S DR++QS + + D G PP+S+ + + I + +D+ P +P N H
Sbjct: 112 LEFEVSITDLVQNGSPRLL-EGQIEVQ--DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAP--KFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-------YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPEN--------NKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQ----GTATVLVNVLDCNDNDPKFMLS-------GYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQST-------------YTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSH 701
BLAST of Protocadherin vs. Ensembl Mouse
Match: Pcdh1 (protocadherin 1 [Source:MGI Symbol;Acc:MGI:104692]) HSP 1 Score: 250.366 bits (638), Expect = 8.471e-69 Identity = 200/679 (29.46%), Postives = 320/679 (47.13%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN-NNLNEPIVD------VSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSD-LIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFV-----EDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P++ P I L+I EN IG+LF IP A D D + F L + D E + P+L + ++DRE D +L I + D G+PP ++ + +LD NDN P F Y L EN + + I V A D D G ++ Y + + V+R ++ G I + +D + + L +S V+A D G S+ V++ + D+ND P I + + + +T + N++E + + V V D D+G N C + G F L + SD Y L D EK I D G P L+S+ + V +VDVNDN P F+ T + E++ G VV +V A D D G N++L+Y + +F + NG + V LDR + + + VV +D G P+L + +N++D N+ P F S ++F+V E+ +P +G + V D DKG NA++ L+++ + F I + G + S DRE++ Y L A+DG V R G V I + D NDN+P P+ S++ + V ED DSG NA + SI G F I ++ L ++++ H G+H+L+V DRG+PP+ + + + ++++
Sbjct: 138 DINDNTPNFASPVITLAIPENTNIGSLFPIPLATDRDAGPNGVASYELQAGPEAQELFGLQ-VAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAPKFERPTYEAELSENSPIGHSV-IQVKANDSDQGANAEIDYTFHQA-PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS--VLAKDRGATPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPENNKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLF--TISPENGEIRVKTSLDR-EQRDSYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMEN-------MPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG--GVPPRSAYVG-VTINVLDENDNAPFIT----APSNTSHRLLTPQTRLGETVSQVTAEDIDSGINAELTYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET 793 HSP 2 Score: 146.362 bits (368), Expect = 3.657e-35 Identity = 159/637 (24.96%), Postives = 272/637 (42.70%), Query Frame = 2
Query: 629 IELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVS--NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD---------PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINK---FQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL--SPKNMVH 2389
+E + +TD +GSP L EG I +Q D+NDN P F++ +++ EN + SL PI + A D D+G G SY+ + A + + +LI + D SY + D G P +SS + + ++D ND P + + + EN+ + ++ V +D DQG N + + H+ +++ + D + + DRE + ++ D G ++ + V + D+NDN PT + +I E T V V+ D+DEG N+ + ++ T + + +++ L + D +++ +V D G P LS+ + + ++D+N+ PVF QS PE+ KP + + SD D G NA+L +++ F IS NG ++ LDRE+++ Y+L ++A D G+P +Q T +V++ + D NDN P F + Y V + AL V D D G NA V LS++ G I S DR++QS + + D G PP+S+ + + I + +D+ P +P N H
Sbjct: 112 LEFEVSITDLVQNGSPRLL-EGQIEVQ--DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ATDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGNPPRASSALLRVTVLDTNDNAP--KFERPTYEAELSENSPIGHSVIQVKANDSDQGANAEIDYTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGATPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-------YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSITEVAFPEN--------NKPGEVVAEVTASDADSGSNAELVYSLEPEPAAQGLFTISPENGEIRVKTSLDREQRDSYELKVVAADRGSPSLQ----GTATVLVNVLDCNDNDPKFMLS-------GYNFSVMENMPALSPVGMVTVIDGDKGENARVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQST-------------YTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPFITAPSNTSH 701
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q08174|PCDH1_HUMAN (Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2) HSP 1 Score: 251.136 bits (640), Expect = 4.694e-68 Identity = 200/679 (29.46%), Postives = 319/679 (46.98%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY--FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFEN-NNLNEPIVD------VSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSD-LIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA-----LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P++ P I L+I EN IG+LF IP A D D + F L + D E + P+L + ++DRE D +L I + D GSPP ++ + +LD NDN P F Y L EN + + I V A D D G ++ Y + + V+R ++ G I + +D + + L +S V+A D G S+ V++ + D+ND P I + + + +T + N++E + + V V D D+G N C + G F L + SD Y L D EK I D G P L+S+ + V +VDVNDN P F+ T + E++ G V+ ++ A D D G N++L+Y + +F + G + V LDR E + + VV +D G P+L + +N++D N+ P F S ++F+V E+ +P +G + V D DKG NAQ+ L+++ + F I + G + S DRE++ Y L A+DG V R G V I + D NDN+P P+ S+K + + ED DSG NA + SI G F I ++ L ++++ H G+H+L+V DRG+PP+ + + + ++++
Sbjct: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQ-VAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSV-IQVKANDSDQGANAEIEYTFHQA-PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS--VLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEI-RGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF--TISPETGEIQVKTSLDREQR-ESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMEN-------MPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG--GVPPRSAYVG-VTINVLDENDNAPYIT----APSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNET 815 HSP 2 Score: 145.976 bits (367), Expect = 3.136e-34 Identity = 162/637 (25.43%), Postives = 270/637 (42.39%), Query Frame = 2
Query: 629 IELVILLTD---SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVS--NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD---------PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINK---FQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIAL------FVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL--SPKNMVH 2389
+E + +TD +GSP L EG I +Q D+NDN P F++ +++ EN + SL PI + A D D+G G SY+ + A + + +LI + D SY + D G P +SS + + ++D ND P + + + EN+ + ++ V +D DQG N + H+ +++ + D + + DRE + ++ D G ++ + V + D+NDN PT + +I E T V V+ D+DEG N+ + ++ T + + +++ L + D +++ +V D G P LS+ + + ++D+N+ PVF QS PE+ KP I I SD D G NA+L +++ F IS G +Q LDRE++E Y+L ++A D G+P +Q T +V++ + D NDN P F + Y V + AL V D D G NA V LS++ G I S DR++QS + + D G PP+S+ + + I + +D+ P +P N H
Sbjct: 134 LEFEVSITDLVQNGSPRLL-EGQIEVQ--DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAP--KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKD-------YTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPEN--------NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQ----GTATVLVNVLDCNDNDPKFMLS-------GYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQST-------------YTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSH 723
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|O60245|PCDH7_HUMAN (Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2) HSP 1 Score: 250.366 bits (638), Expect = 8.760e-68 Identity = 211/693 (30.45%), Postives = 325/693 (46.90%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITID---------DSQPLS----PKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN + + + + A D D G G++ Y + T+SV+R ++ T+G + ++ +D + N+L F V+A D GQP + TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSL+S+ + V + D NDN P F E++ G V V A D D G N+++ Y + + + F I+ + G++LVN LDR + + V D G P L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++N N F I ++ G + S DRE + Y + A+DG + T +V +F+ D NDN+P LP +SY VR + + D D G NA ++ SI G F ID V L KL +H G+H+L+V D G+P +S++ + + ++ DSQ P + +I+K+ + I I V+ ++ + I IV++ CR K K
Sbjct: 241 SSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPI-LQLRAADLDVGVNGQIEYVFGAA-TESVRRLLRLDETSGWLSVLHRIDREEVNQL--RFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLD-----SSVMGIFAIDPDSGDILVNTVLDR-EQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTVT----LPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNK 909
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9HC56|PCDH9_HUMAN (Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2) HSP 1 Score: 240.736 bits (613), Expect = 3.406e-64 Identity = 204/658 (31.00%), Postives = 320/658 (48.63%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDI--TIF--ENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPF-LIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYK----EYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRP 2314
D NDNAP +P P I +SI EN I + F IP A D D T N Y++ S F L + T + ++P+L ++ ++DRE D + I + D G+P + I+ + + DVNDN P F + + + EN + + + I + A D D G+ ++ Y + KR FA+N+T G I + +SLD + E + V V G + + TV IN+ DVND P I L + I T++ E + +N I ++V D D +NG+ CF+ F L K + + + + ++ KE F++ I D G PSL + L+ V + D NDN P F+ P S+ E++ G +T + A D+D G N+ ++Y + N F F L G L ++ DR + E F V D+G P L +Q + + ++D N+ P F + F F V E+ +PK +G I V+D D G N +TL+I DN N ++G+++S DRE++ Y + A DG Q + T V I + D+NDNSP+ P+ S+K + ++A +F D D+G NA + +I G F ID ++ L K G+H+L+V D G P
Sbjct: 134 DTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPD-TGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSV-IQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDRE---ETAIHKVTVLASDGS-STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHL--KAVYDNQYLLETSSLLDYEGTKE-FSF-KIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLG----PNASF--FDLDRKTGVLTASRVFDR-EEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSEN-------LPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGG---QPPRSSTAKVTINVMDVNDNSPVV---ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761 HSP 2 Score: 162.54 bits (410), Expect = 2.989e-39 Identity = 171/587 (29.13%), Postives = 264/587 (44.97%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK---GFDLLFK-QNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSM-----PATSFSIL-EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHL---DRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPG----IIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I I + D NDN P F + IS+ EN +NS PI SA D D+G G Y+ + N SV + + GE +LI + D + +Y + D G P SS+ + + + DVND P+ + ++ I EN + ++ + D D G N + ++ G + LF N + LI Q DRE+ A T+ D S + +T+ + DVNDN P + P L E P+ T + + DKD +N ++I I + PF +++ + NQ+L LLD E FS +V SD G+P+L+ + + L D N+ PP+FNQ +V E+ L L I+ +D D G NA + + N + F + G+L + V DREE+E + T+ A D GTP +Q + +V++ + D NDNSP F H +F + +Y +I V D D+G N V LSI ++ PY + +K N E Q + V D G+PP+SS+ ++ I + D SP
Sbjct: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPI-PSATDPDTGFNGVQHYE--LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPV--FKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIR-YIFGAQVAPATKRLFALNNTTGLITVQ----RSLDREETAIHKVTVLASDGS--STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI-------EREVPFHLKA---VYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLT-------TISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQ----AAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVIT--VTDADAGENKAVTLSILNDNDNFVLDPYSGV------IKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSP 673 HSP 3 Score: 133.265 bits (334), Expect = 3.317e-30 Identity = 157/551 (28.49%), Postives = 243/551 (44.10%), Query Frame = 2
Query: 794 INVSAVDCDSGNFGKLSYKHSVSNTDS--VKRHFAINSTNGEI----------RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING-QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQL--IYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGR-PALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLV-PKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN---KFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE--LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+N+S ++ +G L Y+ D+ VK ++S+ GEI +L Y NE + VV + L + I + D ND P+ + +I+I EN +N S D D G NG Q L G F L + QL+ + DRE++ I D G P +S+ ++ V + DVNDN P F I E++P+GT V ++ A D D G N+++ I+ T ++F L + G + V + LDR + I V V+ SD PA + +TIN+ D+N+ PP N + P + + +L P I I VSD D VN ++ I+ + K + +L++ ++LD E +E+ ++A D G P + T V + L D NDN PIF N P+ ++S E R L + D+DSG NA D+ + G A +F +DR + +R E Q V +D G PP S + +T+ D SPK
Sbjct: 47 LNISHINAATGTSASLVYRLVSKAGDAPLVK----VSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRL---IKIKIIVKDTNDNAPMFP--SPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLF--ALNNTTGLITVQRSLDR-EETAIHKVTVLASDGSSTPA---RATVTINVTDVNDNPP--NIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLN----QTALVRVKLEDENDNPPIF--NQPV-IELSVSENNRRGLYLTTISATDEDSGKNA--DIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPK 571
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q6KEQ9|PC11X_PIG (Protocadherin-11 X-linked OS=Sus scrofa OX=9823 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 237.654 bits (605), Expect = 1.944e-63 Identity = 198/660 (30.00%), Postives = 323/660 (48.94%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHG-QPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS--DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-----HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRP 2314
D+NDNAP +P I +SI EN+ I + + +P +D D T N Y + K S F L + T + + P+L ++ +DRE D + I + D G P + I+ + + D NDN P F ++ +S+ EN + S + + A D D G K+ + S ++ K+ F +NST G I + + LD + ++ +V+A D G PA + V++N+ D+ND +P I +N + + EN LN I ++V D D NG +CF F L + S+ + + A ++ +E +A + D G P L S ++ + + D NDN P F+ P S S+ E++ GT +TK+ A+D D G N+++ Y + P N L G L + LDR E +S V+ D+G P L + + ++D N+ PVF + ++F VPE+ +P+ +G I V+D D G N+ + L+I D + F I G++Q DRE++E Y + A DG +I + T V I + D+NDN P+F + +F L + V ++A+ D D+G NA + S+ G F ID+ ++ L K G+H+L+V KD G+P
Sbjct: 131 DINDNAPLFPATVINISIPENSAINSRYALPATIDPD-TGINGVQNYHLIKGQSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEIEVSIPENAPVGSSV-TQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITIKEPLDREESP--NHKLLVLASDGGLTPARA---MVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNGWVSCFTDHEVPFRL--RPVFSNQFLLETAAYLDYESTRE-YAI-KLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLTKISAMDADSGRNAEINYLLGFDAPSEFN------LDHRTGILTAVKKLDREKQ-EKYSFTVLAKDNGMPPLMTNATVLVTVLDQNDNSPVFTHNEYNFYVPEN-------LPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQESYTFYVKAEDGG---RISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAI---DNDTGMNAELRYSMVGGNTKGLFIIDQTSGNITLKEKCVFADLGLHRLVVKAKDLGQP 759 HSP 2 Score: 145.591 bits (366), Expect = 4.960e-34 Identity = 168/624 (26.92%), Postives = 276/624 (44.23%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCF---LIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSM-----PATSFSIL-EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYV-----RHELIALF-VEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT---IDDSQP--LSPKNMVHFNESKEKINKEMIVITIAVI 2449
I I D+NDN P F IS+ EN +NS + + +D D+G G +Y H + S+ I + GE +LI + D + +Y + D G P SS+ + +++ D ND P+ N+ +++I EN + + + D D G N + + + LI + L + + LI K DRE+ + D G+ + ++ V + D+NDN+P+ + P +L E++P+ T + + DKD N + +D ++ P F SN LL +LD E +++ ++ +D G+P L+ + I + D N+ PVF Q +VPE+ S L I+ D D G NA++ + D ++F + H G+L +V LDRE++E+Y T++A D G P + TV +V+ D NDNSP+F N Y YV RH + L V D D G N+ V LSI + G+I P S DR++Q + V +D GR +SS+ ++ I ++D++P + P + F N +V T+ I
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSRYALPAT-IDPDTGINGVQNY-HLIKG-QSIFGLDVIETPEGEKMPQLIVQKELDREEKDTYVMKIKVEDGGFPQRSSTAILQVSVADTNDNRPVFKENEI--EVSIPENAPVGSSVTQLHATDADIGENAKIHFYFSNLISNMAKKLFHLNSTTGLITI----KEPLDREESPNHKLLVLASDGGL--TPARAMVLVNVTDINDNIPSIDIRYIINPINGTVVLSENAPLNTKIALITVTDKDADHNG-WVSCFTDHEVPFRLRPVF---SNQFLLETAAYLDYESTRE-YAIKLLAADAGKPPLNQSSMLLIKVKDENDNAPVFTQPFLSLSVPENNSPGTQLT-------KISAMDADSGRNAEINYLLGFDAPSEFNLDHRTGILTAVKKLDREKQEKYSFTVLAKDNGMPPLMTNATVLVTVL----DQNDNSPVFTHN-------EYNFYVPENLPRHGTVGLITVTDPDYGENSAVILSILDANDDFTIDPQTGVIQPNISFDREKQES-------------YTFYVKAEDGGRISRSSTAKVTINVVDVNDNKPVFVVPSSNYSFELVPPSTNPGTVVFTVVAI 701
BLAST of Protocadherin vs. UniProt/SwissProt
Match: sp|Q9BZA7|PC11X_HUMAN (Protocadherin-11 X-linked OS=Homo sapiens OX=9606 GN=PCDH11X PE=2 SV=1) HSP 1 Score: 238.039 bits (606), Expect = 3.214e-63 Identity = 209/742 (28.17%), Postives = 365/742 (49.19%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL----NKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYK--------EYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEI-QITIDDS----------------QPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRK 2506
D+NDNAP +P I +SI EN+ I + + +P AVD D N Y++ K + F L + T + + P+L ++ +DRE D + + + D G P + I+ + + D NDN+P F + +S+ EN + + + + A D D G K+ + S ++ +R F +N+T G I + + LD + ++ +V+A D G + + V++N+ DVND +P I + N + + EN LN I ++V D D NG+ CF F L + S+ + + A ++ KE +A + D G P L S ++ + + D NDN P F+ + SI E++ G +TKV A+D D G N+++ Y + P F ++ G L V + LDR + + + ++ D+G P L++ + + +++ID N+ PVF + ++F VPE+ +P+ +G I V+D D G N+ +TL+I D + F I S G+++ DRE++E Y + A DG ++ + + V I + D+NDN P+F P+ SY+ V ++IA+ D D+G NA V SI G F+ID++ ++ L K G+H+++V D G+P S+ I + +++S P++P + S +++V +A I+V+ + FIT V ++CR+
Sbjct: 131 DINDNAPLFPATVINISIPENSAINSKYTLPAAVDPD-VGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV-TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETP--NHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRL--RPVFSNQFLLETAAYLDYESTKE-YAI-KLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGP-----DAPPEFSLDCRTGMLTVVKKLDREKEDK-YLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPEN-------LPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGG---RVSRSSSAKVTINVVDVNDNKPVF---IVPPSNCSYELVLPSTNPGTVVFQVIAV---DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGTITVVVV-IFITAV-VRCRQ 838 HSP 2 Score: 134.42 bits (337), Expect = 1.774e-30 Identity = 161/588 (27.38%), Postives = 263/588 (44.73%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN---CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSM-----PATSFSIL-EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLT-LAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLN--DLNDNSPIFHRNFPLPTKVSYKEYV-----RHELIALF-VEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
I D+NDN P F IS+ EN +NS LP +AVD D G G +Y+ + + ++ I + G+ +LI + D + +Y V D G P SS+ + +++ D ND P+ ++ +++I EN + + + D D G N + + L+ + L + LI K DRE+ + D G+ + + ++ V + DVNDN+P+ + P +L E+ P+ T + + DKD N ++ +D ++ P F SN LL +LD E +++ ++ +D G+P L+ + I + D N+ PVF QS ++PE+ S + L ++ D D G NA++ L D +F + GML V LDRE++++Y T++A D G P +T +V +F++ D NDNSP+F N Y YV RH + L V D D G N+ V LSI + G+I P S DR++Q + V +D GR +SSS ++ I + D
Sbjct: 129 IEDINDNAPLFPATVINISIPENSAINSKYTLP---AAVDPDVGINGVQNYE--LIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV--FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITI----KEPLDREETPNHKLLVLASDGGL--MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTC-FTDHEIPFRLRPVF---SNQFLLETAAYLDYESTKE-YAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLT-------KVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVP------PLTSNVTVFVSIIDQNDNSPVFTHN-------EYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQES-------------YTFYVKAEDGGRVSRSSSAKVTINVVD 665 HSP 3 Score: 129.413 bits (324), Expect = 5.988e-29 Identity = 126/462 (27.27%), Postives = 224/462 (48.48%), Query Frame = 2
Query: 1034 IVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKG-FDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISD--PRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDP-------SDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI----SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I D+ND P+ ++ +I+I EN+ +N + D D GING N LI + F L + + QL+ + + DRE++ + D G P +S+ ++ V + D NDN P F SI E++P+GT VT++ A D D G N+++ + S+ ++F L + G + + + LDR + ++V+ SD G + + + +N+ D+N+ P + + V +P S+++PL K I I V+D D N ++T D+ F++ S+ +L++ A LD E +EY + L+A D G P + + + I + D NDN+P+F ++F + + +L + D DSG NA ++ + P P FS+D + + +KL E + + ++ KD G PP +S++ + ++I D SP
Sbjct: 129 IEDINDNAPLFP--ATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLF--HLNATTGLITIKEPLDR-EETPNHKLLVLASDGG--LMPARAMVLVNVTDVNDNVPSID---IRYIV--NPVNDTVVLSENIPLNTK---IALITVTDKDADHNGRVT-CFTDHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLN----QSAMLFIKVKDENDNAPVFTQSF-VTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPD-APPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP 568 HSP 4 Score: 78.1814 bits (191), Expect = 3.153e-13 Identity = 95/370 (25.68%), Postives = 164/370 (44.32%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD---NINK--FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVV----DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I +I D+NDN P F + SI E+S I + T A+D D G+N Y + + +F +IE+ G+ L+V + LDR + + + + V V D G P S+ + +++ D N+ PVF ++ ++PE+ P ++ + +D D G NA++ + + NI + F + + G++ LDREE +KL ++A DG V++ + D+NDN P + N PL TK++ + V DKD+ N V D I P + P FS ++ ++ L E + + ++ D G+PP + S + I + D +P
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIK---SQNIFGLDVIETPEGDKMPQLIVQKELDR-EEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPEN-------APVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGG-----LMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIAL----------ITVTDKDADHNGRVTCFTDHEI-PFRLRPVFS---NQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAP 464
BLAST of Protocadherin vs. TrEMBL
Match: A0A158QIB0 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS9059 PE=4 SV=1) HSP 1 Score: 332.798 bits (852), Expect = 5.373e-95 Identity = 263/865 (30.40%), Postives = 408/865 (47.17%), Query Frame = 2
Query: 200 MLHVHSYFRL--SSSGIISVARQLDCDNDSNLCDKTL--EYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWP-------------KP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQF------------PKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTH------------KYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKS------LKDITIF-------------ENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTV--TGSVVIFLNDLNDNSPIFHRNFP--------LPT-KVSYKEYVRHELIALFVEDKDSGANAVVDLSI-----KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPL-SPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKA 2560
+L +YF L S + V R LD DND LC + E C + ++ +V + I I D NDN P WP KP IEL I+EN I +LF++P A D D ++ + + T+++ +F P+L++ +DRE D E+ I D G+ + + ++D NDN P F TH K++I + E+ +NS LP++ A D DSG+FG++ Y+ S S + V+R F+I T G I + +LD D+G Y F +VA D L++ TV+I + DVND P ISL + L D T F E + + V+V D D +G+F C L G F L + +YQL++ +FDRE EA T+ C D G P SS++I + ++DVNDN P F P FSI E+ P GT+V +V D D G+N ++ +S +Q F I G + N+ LDR + + VV D G+P+ E+TI + D N+C P F +HF++ ED + V R +G + D D G NA++ I++ + F+IS NG + +V LDRE K Y L+++A D P Q ++ T V + + D+ND++P+F FP +P K+S E + H + L +D D+G NA + S+ P F + D + + KL + H L V D G PP SS++ +QI +D + P SP + +E + +N +++ I +S+ + I I + +++K C+ + KA
Sbjct: 62 ILQDTTYFSLIGSHQNTVVVNRLLDRDNDRKLCREPTWPEVCAWSGVLFAHDGVVLSLRITITDANDNIPRWPESALSKPRNSKDGKPAIELLIAENTPIRSLFDLPLADDRD------------YGKNGIVNYELITTENQGRFSLICTTGPNGVVPRLQVLEMLDREERDEYEMQIAAIDGGNQKTIAG--LYVYLVDENDNSPIF-THLKNLPEEEKQRTKFVIEVDESIPVNSALPMHPVATDADSGDFGRVRYRFSFSTPEYVRRDFSIEPTTGNIIVQNNLDCDAGGVAEYVFSMVAEDSAPQPLTAVATVVIIVHDVNDNAPTISLTPATLKTDGLYDSTFFPSFEDSRDTFHLIEEMPSGQLVATVAVTDPDSDQDGEFFCDLGGSSDFTLHALPWIGATKVYQLLSARRFDREVEALISVTLKCVDRGNPPQASSKIIPITLIDVNDNRPYFQQPIYQFSIRENKPPGTLVGRVIVQDNDAGINGEVDITLSCKTGRHQHL--FSINEKGEIRSNEVLDREANPKRIQFTVVAEDRGKPSFRTTAEVTIEIEDENDCSPKFAFQNYHFSIEEDQEAYRRTV---REVGSVQAFDQDIGPNAEIQYLIEEPDSPFEISQNGTIYAVRKLDREVKSTYLLSVMAKD-LPTQQFEKSLNSTTQVRVTITDINDHAPVFI--FPRLNTSSDAIPKIKLSALEPIGHRIAKLQAKDADTGTNAKIRYSLLENSRLPMGTEKLFHLSEDSGELFIAAKLPTSKGSSHHLKVQATDGGSPPLSSTLSLQIVLDPTLPATSPGDSSGHDEGGDVLNNIYLIVIITFAVSIAFVILVIAIYFMSKDRRSK-GYCCFASSSARNKA 902
BLAST of Protocadherin vs. TrEMBL
Match: A0A4V3SCX5 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009656 PE=4 SV=1) HSP 1 Score: 328.946 bits (842), Expect = 1.341e-92 Identity = 245/809 (30.28%), Postives = 386/809 (47.71%), Query Frame = 2
Query: 251 VARQLDCDNDSNLCDKTL--EYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWP--------KPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXS----SYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHK--------------YIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPII--------------SLNKSLK-DITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPL-VPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR----NFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD---SQPLSPKNMVHFNESKE------KINKEMIVITIAVIISVLALGSFITIVIIKCRK 2506
V LD D D LC + E C I ++ + + I++ D+NDN P W +++S++EN +GT ++P A D D + ++ +++ + FD+ + ++ KL ++ +DRET L+I D G G +TI I D NDN P F+ K + I++ E+ + S LP A D D G+FG+++Y ++S + VKR F I+ G I + LDYD+G Y FV+VA DHG P L++S+ VII + D ND PII S K K + + EN I ++VHD D G NG+F C L L F +NL L +YQL + DRE T+ C D+G+P S++L+ V I DVNDN P F SF E + ++ V A+D D G+N++L Y I P NQ PF+I + G + LDR E F V+ DHG P+LS ++ + LID+N+C P F Q +HFTV E+ +P + IG + +DCD G NAQ+ ++ FQIS +G L + +DRE+ + +T+ AID + R + V I + D+NDN PIF R N +S E + +++ + DKD N + + + F+++ + + L R+L E GI L ++ D G P++++ I+I D ++P S + ++E ++N +I V+I+++ ++ + RK
Sbjct: 83 VKSPLDRDTDRKLCSEGGWPEVCSWSGVIFSSDGRLLSLRIVVRDVNDNTPSWLTSQQHDGLAQLQISVTENCPLGTAIDLPLASDPDVGSNSVVNYERVIQEAVDHRAPFDIISTREPNGVRY-KLVVRGKLDRETTPLYRLMIAAVDGGGN--RGLAQLTILIADENDNRPVFTHTKMEESQSDLGEQQTEFTITIDEDLPVGSRLPRYPVATDADEGDFGRITYSFAISVAEVVKRDFRIDEVTGAIFVRAPLDYDTGGLTHYQFVIVAQDHGIPPLTASSKVIIEVQDRNDNAPIITVTPTTTATMTSSKSNEKHEKTSLHLLENAPSGSLIATITVHDPDSGENGKFMCQLGKVDSLRLEFLKNLGKLSVYQLYSSLPLDRESNPEIRVTLRCRDHGVPGRVSTELLMVNISDVNDNAPMFVNHRYSFQTSEGNDQDELIGLVTAVDSDSGVNAELSYSIIWP--NNQGLNPFIINARGEIRARMTLDRESRPEGFQFTVLAKDHGVPSLSALAKVEVALIDVNDCSPTFTQGVYHFTVEEE----IPFNLSNAYVIGQVKATDCDIGNNAQILYQLETTDAPFQISSDGYLSTTRPIDREQSSSFVITIQAIDSPQTTERRLSSFAEVQITVVDINDNDPIFLRPPFENGTHQVTLSIYEDINCKVVKIEAIDKDIERNGEIRFRLANDVSRGMFALNPESGELTLKRRLTVEEVGIIPLRILAIDNGLKPRTATTTIEILAADVPATKPTSFSGNLDYSEQPNTFLGNLRVNANKFIIVCIVVITLIICLILAAVICVVSRK 882
BLAST of Protocadherin vs. TrEMBL
Match: A0A5J4NT48 (Protocadherin delta 1 OS=Paragonimus westermani OX=34504 GN=DEA37_0000856 PE=4 SV=1) HSP 1 Score: 319.316 bits (817), Expect = 3.156e-90 Identity = 237/761 (31.14%), Postives = 371/761 (48.75%), Query Frame = 2
Query: 263 LDCDNDSNLC--DKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKP-------IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSY----FDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTF-----------STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL-----------NKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN----IGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR-NFPLPT-KVSYKEYVRHELIALFVE--DKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKIN 2416
LD D D LC + E C I ++N + + +II D+NDN P W ++ ++SEN +GT ++P A+D D + + + S FD+ + T + + +L + +DRE + + D G G +TI + D NDNYP F ++I + E+ + + LP AVD D G FG+L Y S+S D VKR F I+ GEI + LDYD+G + Y F+VVA DHG P L +S VI+NI D ND PII++ ++ ++T+ EN+ + I ++VHDLD G NG F C L L + +++ + I+QL++ DRE + C D+G+PS S++L+ V I+DVNDN P F+ SF E G + + A D D LN+Q+ Y I P+ Q PF+I SNG L + LDR E + V+ D G P LS+ ++ + LID+N+C P F Q+ ++F+V E+ +P N IG + +DCD G NAQ+ + F++S+ G L + + +RE + + L L A+D + R + T + I + D+NDN P+F R F T ++ + + E + +VE D+D G N V + F++ + + L R L E G + L V+ D G PK+++ +I+I I D P + +E+ +N
Sbjct: 87 LDRDADRQLCIENGWPETCSWSGVIFVSNGRLLALRVIIRDVNDNTPSWSTKHKDGMAVLQTTVSENCPLGTTVDLPLAIDPDFGGNSIVRYEMVTQGISEGRPPFDVLSVNTSNGVIY-RLVVNGLLDREQKPNYIVTVGAIDGGGN--KGLARLTINVADENDNYPQFVHLKNDTERLHDDQGFVIYIDEDLPVGTRLPRCPVAVDDDEGEFGRLMYSFSISTGDVVKRDFRIDEHVGEIFVRSKLDYDAGGLIQYEFLVVAQDHGLPPLVASARVIVNIQDKNDNPPIITVTSVQRSTDWNNSRGRSNLTLPENSLAGKLIATLTVHDLDSGKNGMFTCKLGETNQLQLSYLKSMGKMNIFQLISTQPVDREMRTELRVMLRCSDHGMPSQVSTELLVVKIIDVNDNPPRFTNQHYSFQTPEGDAAGQFIGSITAYDSDSDLNAQITYFIEWPQI--QESNPFIINSNGELKAHLPLDRESQPEGYQFTVIAHDSGSPRLSSYAKVEVALIDVNDCAPNFTQNVYYFSVEEE-------LPAATNSTYVIGQVKATDCDIGSNAQVNYYLDSLGALFKVSNEGYLYTSSTFNRESQAVFTLKLSAVDSAHAPEQRLSSTAEIQITVTDINDNEPVFVRPPFENGTNEILLSVHEKPESLVTWVEATDEDDGQNGFVSYLLVGE--KRTFNLHSNSGELILLRMLSVEDLGKYPLTVLAVDSGEQPKTATAQIEIRIADIPPKEASQSMKDSETGLSMN 833
BLAST of Protocadherin vs. TrEMBL
Match: A0A419QFC3 (Protocadherin-11 X-linked OS=Clonorchis sinensis OX=79923 GN=PCDH11X PE=4 SV=1) HSP 1 Score: 322.013 bits (824), Expect = 7.999e-90 Identity = 248/853 (29.07%), Postives = 401/853 (47.01%), Query Frame = 2
Query: 251 VARQLDCDNDSNLCDKTL--EYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWP--------KPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXS----SYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHK--------------YIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL-------------NKSLK--DITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPL-VPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR----NFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD---SQPLSPKNMVHFNESKE------KINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISDMDISMNFKVFNEENCMEC 2638
V LD D D LC + E C I ++ + + I++ D+NDN P W +++S++EN +GT ++P A D D + ++ +++ + FD+ + ++ KL ++ +DRET L+I D G G +TI I D NDN P F+ K + I++ E+ + S LP A D D G+FG+++Y ++S + VKR F I+ G I + LDYD+G Y FVVVA DHG P L++S+ VII + D ND PII++ N+ L+ + + EN I ++VHD D G NG+F C L L F +NL L +YQL + DRE T+ C D+G+P S++L+ V I DVNDN P F SF E + ++ V A+D D G+N++L Y I P NQ PF I + G + LDR E F V+ D+G P+LS ++ + LID+N+C P F Q +HFTV E+ +P + IG + +DCD G NAQ+ ++ FQIS +G L + +DRE+ + +T+ A D + R + V I + D+NDN PIF R N +S E + ++++ + DKD N + + + F+++ + + L RKL E GI L ++ D G P++++ I+I D ++P + ++E ++N +I V+I+++ ++ + R+ ++K + + S+ + + VF+ ME
Sbjct: 138 VKSPLDRDTDRKLCSEGGWPEVCSWSGVIFSSDGRLLSLRIVVRDVNDNTPSWLTSQQHDGLAQLQISVTENCPLGTAIDLPLASDPDVGSNSVVNYERVIQEAVDHRAPFDIISTKEPNGVRY-KLVVRGKLDRETTPLYRLMIAAVDGGGN--RGLAQLTILIADENDNRPVFTHMKMEESQSDLDEQQTEFTITIDEDLPVGSRLPRYPVATDADEGDFGRITYSFAISVAEVVKRDFRIDEVTGAIFVRAPLDYDTGGLTHYQFVVVAQDHGIPPLTASSKVIIEVQDRNDNAPIITVTPTITTTAPSSKSNEKLEKTSLQLLENAPSGSLIATITVHDPDSGENGKFTCQLGKVDSLRLEFLKNLGKLSVYQLYSTLPLDRESNPEVRVTLRCRDHGVPGRVSTELLMVNISDVNDNAPMFMNHRYSFQTTESNDQDELIGLVTAVDADSGVNAELSYSIIWP--NNQGLNPFTINARGEIRARMTLDRESRPEGFQFTVLAKDNGVPSLSALAKVEVALIDVNDCSPTFTQGVYHFTVEEE----IPFNLSNAYVIGLVKATDCDIGNNAQIFYQLEATDAPFQISSDGYLSTTRPIDREQSSSFVITIQATDSPQITERRLSSFAEVQITVVDINDNDPIFLRPPFENGTHQVALSIYEDINYKVVKIEAIDKDIERNGEIRFKLANDVPRGMFALNPESGELTLKRKLTVEEAGIIPLRILAIDNGLKPRTATTTIEILAADVPATKPTGISGNLDYSEQPNTFLGNLRVNANKFIIVCIVVITLIICLILAAVICVVSRRGCAAWTGAPNTSARNQKQIHLVSHSNGGLPLTEPVFSTAPDMEA 981 HSP 2 Score: 106.686 bits (265), Expect = 1.689e-19 Identity = 146/581 (25.13%), Postives = 248/581 (42.69%), Query Frame = 2
Query: 530 SSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPL-TGEGII----------TIQILDVNDNYPTFSTH-------KYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINST---NG-EIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS---LNKSLKD---------ITIFENNNLNEPIVDVSVH-DLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYT--TITCCDYGIPSLTSSQLITVIIVDVNDNLPTF-----------------SMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQ-----HLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE-DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI----KDNINKFQISHNGMLQSVAVLDREEK-EEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRN 2071
+SYFD D HQ L +KS +DR+T+ + L ++ G P + + G+I I + DVNDN P++ T + IS+ EN L + + + + A D D G+ ++Y+ + + F I ST NG +L+ D Y ++ A D G + T++ I D ND P+ + + +S D ITI E+ + + V D D+G G+ F I +++ + D + + + D + + + D+GIP LT+S + + + D NDN P + TS +LE++P G+++ + D D G N + + + F +++ G L V Q LDR + E+ V + DHG P + + +N+ D+N+ P+F + F E + D L IG + D D GVNA+L+ +I +N F I+ G +++ LDRE + E ++ T++A D G P + + V + L D+ND SP F +
Sbjct: 123 TSYFDF------DPHQPNTLIVKSPLDRDTDRK-----LCSEGGWPEVCSWSGVIFSSDGRLLSLRIVVRDVNDNTPSWLTSQQHDGLAQLQISVTENCPLGTAIDLPL-ASDPDVGSNSVVNYERVIQEAVDHRAPFDIISTKEPNGVRYKLVVRGKLDRETTPLYRLMIAAVDGGGNRGLAQLTIL--IADENDNRPVFTHMKMEESQSDLDEQQTEFTITIDEDLPVGSRLPRYPVATDADEGDFGRITYSFAISVA--EVVKRDFRIDEVTGAIFVRAPLDYDTGGLTHYQFVVVAQDHGIPPLTASSKVIIEVQDRNDNAPIITVTPTITTTAPSSKSNEKLEKTSLQLLENAPSGSLIATITVHDPDSGENGKFTCQLGKVDSLRLEF----LKNLGKLSVYQLYSTLPLDRESNPEV-RVTLRCRDHGVPGRVSTELLMVNISDVNDNAPMFMNHRYSFQTTESNDQDEL--------IGLVTAVDADSGVNAELSYSIIWPNNQGLNPFTINARGEIRARMTLDRESRPEGFQFTVLAKDNGVPSL----SALAKVEVALIDVNDCSPTFTQG 670
BLAST of Protocadherin vs. TrEMBL
Match: A0A158REZ2 (Uncharacterized protein OS=Hydatigena taeniaeformis OX=6205 GN=TTAC_LOCUS8401 PE=4 SV=1) HSP 1 Score: 319.316 bits (817), Expect = 3.395e-89 Identity = 247/810 (30.49%), Postives = 380/810 (46.91%), Query Frame = 2
Query: 200 MLHVHSYFRLSSSG--IISVARQLDCDNDSNLCDKTL--EYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWP-----KP---------IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQF------------PKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIIT---IQILDVNDNYPTF-----------STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKS------LKDITIF-------------ENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVI-------VVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPED--PSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTV--TGSVVIFLNDLNDNSPIFHRNFP--------LPT-KVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGI----IAPYFSIDRDRQSVKLNRKLKSEHQGI-HKLIVIGKDRGRPPKSSSIEIQITIDDSQP 2365
ML +YF L G I+ V R LD DND LC + E C + ++ +V + I + D+NDN P WP KP IEL I+EN G++F++P A D D + + + D +F P+L++ +DRE + E+ I D G G+ ++ + ++D NDN P F +++I + E+ + + LP + A D D+G+FG++ Y+ S S + VKR FAI S G+I + LD D+G Y F ++A D L++ TV+I + DVND PIISL + + D T + E + + V+V D D +G+F C L + F L + +YQL++ +FDRE EA T++C D G+P SS++I + ++D+NDN P F FSI E+ P GT+V +V D D G N + + IS T Q F I G + N+ LDR + + + I VV D GRP +E+ I + D N+C P F+ +HF++ ED P H PR +G + SDCD G NA++ ++ F+IS NG + +V LDRE K Y LT++A D P T+ T V I + D+ND+SP+F FP LP ++S E + + + L +D DSG NA + ++ + F + D + + KL + + + + L V D G PP+SS+ + I +D + P
Sbjct: 70 MLQDTTYFALRGPGQKIVVVNRLLDRDNDRKLCREASWPETCAWSGVLFAHDGVVFSLRITVIDVNDNIPRWPDSALSKPRNSEEKEPSIELFIAENTPTGSMFDLPLAEDRD------------YGNNGIVNYELVEMDKNGRFSLRCTNGPNGVIPRLQVLEMLDREEREEYEMQIAAADGG-----GQRVVVGLRVYLVDENDNPPIFVHLKNASQEEAQRARFVIEIDESLAIGTALPFHPIATDADAGDFGRVRYRFSFSTPEFVKRDFAIESETGKIIVKNILDCDAGGIPEYVFSMIAEDGAPQPLTALATVVIALHDVNDNAPIISLTPATPKIEDMYDTTFYPTFEDSRDTFCLVEEMPSGQMVATVAVTDPDSDADGEFECGLSTTQDFALHALPWIGATKVYQLLSARRFDREMEALTSVTLSCVDRGVPPRVSSKIIPITLIDINDNRPYFQQQFYQFSIPENRPPGTLVGRVIVQDNDAGKNGLVDFSIS--CKTGQYQHLFSISGMGEVRANEMLDRETNPQNYLEIICFLILKVVAEDKGRPTYRTSVEVCIEIEDENDCIPKFDFPNYHFSIDEDVEPYKH-----GPREVGIVQASDCDTGGNAEIHFFLEGTDTPFKISSNGTIFAVQQLDREIKSSYLLTVVARDSPPPRSPDKTLNSTAQVRITVTDINDHSPVFI--FPRLNSTSGSLPEIRMSALEPIGYRVAKLQAKDADSGVNADIRYTLTEELSVSSTEKLFRVSEDSGELFIAAKLSTSTKEMRYPLQVHATDGGTPPRSSTFNLIIYLDPTLP 853
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 254.218 bits (648), Expect = 1.213e-69 Identity = 204/674 (30.27%), Postives = 330/674 (48.96%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS---------DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-----HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEI 2338
D+NDNAP + I +SI EN I + +P A D D Q +K + F L + T + ++P+L ++ ++DRET D + I + D G+PP + I+ + + DVNDN P F + +++ EN + + + + A D D G+ ++ + S + + KRHFAI+S+ G I + + LD +S + +V+A D A S TVI+N+ DVND +P I +N + + EN LN I ++V D D +NG+ C+ F L K +D + + A ++ +E +A I D G P L +S ++ + I D NDN P F P SI E++ GT + K+ A D D G N+ +IY + DPR+ G L V++ LDR E +S V+ D+G L + + + + + D N+ P F + ++F VPE+ LPL +G I V+D D G NA +TL+I + + F I G+++ DRE++ Y + A+D I+ T V I + D+NDN P+F + ++ L V + + +F D D+G NA + SI G F+ID+ ++ L K+ + QG+H+L+V KD G+P SI +
Sbjct: 131 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-TQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNP--VHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRL--KPVFNDQFLLETAAPLDYETTRE-YAI-KIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRS-------------GILSVSKRLDREKQ-EKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPEN----LPLY---GTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSG---LIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL---VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIAL 768 HSP 2 Score: 136.732 bits (343), Expect = 3.107e-32 Identity = 136/466 (29.18%), Postives = 224/466 (48.07%), Query Frame = 2
Query: 1034 IVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING--QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPP----FLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDP----SDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN---KFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPT-KVSYKEY--VRHELIALFVEDKDSGANAVVDLSIKPGIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I D+ND P+ ++ +I+I EN +N S D D GING + +G F L + QL+ + DRE + I D G P +S+ ++ V + DVNDN P F ++ E++P+GT VT++ A D D G N+Q+ + S NQ+ P F I+S+ L+ V Q LDR + +IV+ SD A ++ + +N+ D+N+ P + T + P + S++ PL K I I V+D D +N ++T ++ K + +L++ A LD E EY + ++A D G P + + V+I + D NDN+P+ FP P ++S E +LI + D DSG+NA++ S+ P AP F+ID + ++++L E Q + VI +D G P S++ +++ + D SP
Sbjct: 129 IEDINDNAPL--FQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFS-----NQISPATKRHFAIDSSTGLITVKQPLDR-ESNPVHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSID--TRYIMNPVNGTVLLSENAPLNTK---IALITVTDRDADLNGKVTCYTDHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLN----TSAMVLIKIKDENDNAPV----FPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPD--APDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSP 569 HSP 3 Score: 129.028 bits (323), Expect = 8.557e-30 Identity = 148/547 (27.06%), Postives = 241/547 (44.06%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINST---NGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVI-IVDVNDNLPT----FSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP----PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE--DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL-----IALF-VEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQS 2233
I D+NDN P F + IS+ EN +N+ P+ SA D D G G Y+ + +++ I T + +LI + D + ++ + D G P SS+ + + + DVND P+ S ++ + EN + + + D D G N Q + F ++ + D + K DRE + D S T S+ ++ + DVNDN+P+ + M + ++L E++P+ T + + D+D LN ++ + +D ++ P FL+E+ L + +++ +V SD G+P L+ + I + D N+ PVF Q ++PE DP L I +D D G NA + ++ D + F I +G+L LDRE++E+Y T+IA D G+ +Q TV + + D NDNSP F T Y YV L + L V D D+G NA+V LSI K G+I P + DR++QS
Sbjct: 129 IEDINDNAPLFQSTVINISIPENTAINNRYPV-PSAFDPDVGINGIQHYE--LVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPV--FKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIH-FSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDG---SATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCY-TDHDVPFRLKPVFNDQFLLETAAPLDYETTRE-------YAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLI---------KITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVK----LIVQDQNDNSPAF-------THAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQS 638 HSP 4 Score: 84.3445 bits (207), Expect = 5.179e-16 Identity = 96/371 (25.88%), Postives = 156/371 (42.05%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDG--TPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIK---PGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I +I D+NDN P F + SI E++ I A D D G+N I H + F +IE+ G+ L+V Q+LDR + F + + V D G P S+ + + + D+N+ PVF S VPE+ P ++ + +D D G NAQ+ + + I+ H G++ LDRE +KL ++A DG TP +V++ + D+NDN P + N PL TK++ + V D+D+ N V P + P F+ D+ ++ L E + + ++ D G+PP ++S + I I D +P
Sbjct: 125 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGING--IQHYELVKVGALEFGLDIIETPEGDKWPQLIVQQNLDRETK-DTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPEN-------APMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPS-------RATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIAL----------ITVTDRDADLNGKVTCYTDHDVPFRLKPVFN---DQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAP 465
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 252.292 bits (643), Expect = 2.248e-69 Identity = 205/674 (30.42%), Postives = 330/674 (48.96%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS---------DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-----HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEI 2338
D+NDNAP + I +SI EN I + +P A D D Q +K S F L + T + ++P+L ++ ++DRET D + I + D G+PP + I+ + + DVNDN P F + +++ EN + + + + A D D G+ ++ + S + + KRHFAI+S+ G I + + LD +S + +V+A D A S TVI+N+ DVND +P I +N + + EN LN I ++V D D +NG+ C+ F L K +D + + A ++ +E +A I D G P L +S ++ + I D NDN P F P SI E++ GT + K+ A D D G N+ +IY + DPR+ G L V++ LDR E +S V+ D+G L + + + + + D N+ P F + ++F VPE+ LPL +G I V+D D G NA +TL+I + + F I G+++ DRE++ Y + A+D I+ T V I + D+NDN P+F + ++ L V + + +F D D+G NA + SI G F+ID+ ++ L K+ + QG+H+L+V KD G+P SI +
Sbjct: 171 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSE-FGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-TQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNP--VHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRL--KPVFNDQFLLETAAPLDYETTRE-YAI-KIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRS-------------GILSVSKRLDR-EKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPEN----LPLY---GTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSG---LIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL---VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIAL 807 HSP 2 Score: 132.109 bits (331), Expect = 8.213e-31 Identity = 136/465 (29.25%), Postives = 223/465 (47.96%), Query Frame = 2
Query: 1034 IVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING-QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPP----FLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDP----SDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN---KFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPT-KVSYKEY--VRHELIALFVEDKDSGANAVVDLSIKPGIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I D+ND P+ ++ +I+I EN +N S D D GING Q + F L + QL+ + DRE + I D G P +S+ ++ V + DVNDN P F ++ E++P+GT VT++ A D D G N+Q+ + S NQ+ P F I+S+ L+ V Q LDR + +IV+ SD A ++ + +N+ D+N+ P + T + P + S++ PL K I I V+D D +N ++T ++ K + +L++ A LD E EY + ++A D G P + + V+I + D NDN+P+ FP P ++S E +LI + D DSG+NA++ S+ P AP F+ID + ++++L E Q + VI +D G P S++ +++ + D SP
Sbjct: 169 IEDINDNAPL--FQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFS-----NQISPATKRHFAIDSSTGLITVKQPLDR-ESNPVHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSID--TRYIMNPVNGTVLLSENAPLNTK---IALITVTDRDADLNGKVTCYTDHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLN----TSAMVLIKIKDENDNAPV----FPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPD--APDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSP 608 HSP 3 Score: 130.568 bits (327), Expect = 2.405e-30 Identity = 146/543 (26.89%), Postives = 236/543 (43.46%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPT----FSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP----PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE--DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL-----IALF-VEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQS 2233
I D+NDN P F + IS+ EN +N+ P+ SA D D G G Y+ S ++ + +LI + D + ++ + D G P SS+ + + + DVND P+ S ++ + EN + + + D D G N Q + F ++ + D + K DRE + D + S + V + DVNDN+P+ + M + ++L E++P+ T + + D+D LN ++ + +D ++ P FL+E+ L + +++ +V SD G+P L+ + I + D N+ PVF Q ++PE DP L I +D D G NA + ++ D + F I +G+L LDRE++E+Y T+IA D G+ +Q TV + + D NDNSP F T Y YV L + L V D D+G NA+V LSI K G+I P + DR++QS
Sbjct: 169 IEDINDNAPLFQSTVINISIPENTAINNRYPVP-SAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPV--FKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIH-FSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCY-TDHDVPFRLKPVFNDQFLLETAAPLDYETTRE-------YAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQL---------IKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVK----LIVQDQNDNSPAF-------THAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQS 677 HSP 4 Score: 84.3445 bits (207), Expect = 4.237e-16 Identity = 93/370 (25.14%), Postives = 155/370 (41.89%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDG--TPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIK---PGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I +I D+NDN P F + SI E++ I A D D G+N I H ++ ++ + G+ L+V Q+LDR + F + + V D G P S+ + + + D+N+ PVF S VPE+ P ++ + +D D G NAQ+ + + I+ H G++ LDRE +KL ++A DG TP +V++ + D+NDN P + N PL TK++ + V D+D+ N V P + P F+ D+ ++ L E + + ++ D G+PP ++S + I I D +P
Sbjct: 165 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGING--IQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETK-DTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPEN-------APMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPS-------RATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIAL----------ITVTDRDADLNGKVTCYTDHDVPFRLKPVFN---DQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAP 504 HSP 5 Score: 52.373 bits (124), Expect = 2.637e-6 Identity = 61/277 (22.02%), Postives = 123/277 (44.40%), Query Frame = 2
Query: 1676 IEITINLIDINNCPPVFNQSTFHFTVPEDPS--DHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKF-----QISHNGMLQSVAV---LDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAP----YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQP-------LSPKNMVHFNESKEKINKEMIVITI 2440
++I + DIN+ P+F + + ++PE+ + + P VP + D D G+N + ++++F + + V LDRE K+ + + + DG + T + + ++D+NDN P+F ++ + V + + L D D G+NA + S I+P +F+ID + + + L E +HKLIV+ D P +++ + +T ++D+ P ++P N +N ++ +IT+
Sbjct: 163 VKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYP-VP--------SAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGG---NPPKSSTAILQVTVSDVNDNRPVF-KDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFS-NQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITV 425
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 253.062 bits (645), Expect = 3.640e-69 Identity = 205/674 (30.42%), Postives = 330/674 (48.96%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS----LNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS---------DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-----HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEI 2338
D+NDNAP + I +SI EN I + +P A D D Q +K S F L + T + ++P+L ++ ++DRET D + I + D G+PP + I+ + + DVNDN P F + +++ EN + + + + A D D G+ ++ + S + + KRHFAI+S+ G I + + LD +S + +V+A D A S TVI+N+ DVND +P I +N + + EN LN I ++V D D +NG+ C+ F L K +D + + A ++ +E +A I D G P L +S ++ + I D NDN P F P SI E++ GT + K+ A D D G N+ +IY + DPR+ G L V++ LDR E +S V+ D+G L + + + + + D N+ P F + ++F VPE+ LPL +G I V+D D G NA +TL+I + + F I G+++ DRE++ Y + A+D I+ T V I + D+NDN P+F + ++ L V + + +F D D+G NA + SI G F+ID+ ++ L K+ + QG+H+L+V KD G+P SI +
Sbjct: 171 DINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSE-FGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSV-TQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNP--VHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCYTDHDVPFRL--KPVFNDQFLLETAAPLDYETTRE-YAI-KIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPDAPDGFNIDPRS-------------GILSVSKRLDREKQ-EKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSPAFTHAEYNFYVPEN----LPLY---GTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQSSYTFVVKAVDSG---LIQTTSYAKVTINVVDVNDNRPVFVIPSSNYSYDL---VPFTTNPGSVVTRVFAIDNDTGMNAELQYSIIGGSPRGLFAIDKTTGNITLQEKIANADQGLHRLVVKVKDLGQPESLHSIAL 807 HSP 2 Score: 133.265 bits (334), Expect = 4.148e-31 Identity = 136/465 (29.25%), Postives = 223/465 (47.96%), Query Frame = 2
Query: 1034 IVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING-QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPP----FLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDP----SDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN---KFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPT-KVSYKEY--VRHELIALFVEDKDSGANAVVDLSIKPGIIAP-YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I D+ND P+ ++ +I+I EN +N S D D GING Q + F L + QL+ + DRE + I D G P +S+ ++ V + DVNDN P F ++ E++P+GT VT++ A D D G N+Q+ + S NQ+ P F I+S+ L+ V Q LDR + +IV+ SD A ++ + +N+ D+N+ P + T + P + S++ PL K I I V+D D +N ++T ++ K + +L++ A LD E EY + ++A D G P + + V+I + D NDN+P+ FP P ++S E +LI + D DSG+NA++ S+ P AP F+ID + ++++L E Q + VI +D G P S++ +++ + D SP
Sbjct: 169 IEDINDNAPL--FQSTVINISIPENTAINNRYPVPSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFS-----NQISPATKRHFAIDSSTGLITVKQPLDR-ESNPVHKLIVLASDGS--ATPSRATVIVNVTDVNDNVPSID--TRYIMNPVNGTVLLSENAPLNTK---IALITVTDRDADLNGKVTCYTDHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDSGKPPLN----TSAMVLIKIKDENDNAPV----FPQPEIQLSIPENNDPGTQLIKITATDADSGSNALIIYSLGPD--APDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVKLIVQDQNDNSP 608 HSP 3 Score: 131.339 bits (329), Expect = 1.539e-30 Identity = 147/544 (27.02%), Postives = 238/544 (43.75%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVI-IVDVNDNLPT----FSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFP----PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPE--DPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL-----IALF-VEDKDSGANAVVDLSI-----------KPGIIAPYFSIDRDRQS 2233
I D+NDN P F + IS+ EN +N+ P+ SA D D G G Y+ S ++ + +LI + D + ++ + D G P SS+ + + + DVND P+ S ++ + EN + + + D D G N Q + F ++ + D + K DRE + D S T S+ ++ + DVNDN+P+ + M + ++L E++P+ T + + D+D LN ++ + +D ++ P FL+E+ L + +++ +V SD G+P L+ + I + D N+ PVF Q ++PE DP L I +D D G NA + ++ D + F I +G+L LDRE++E+Y T+IA D G+ +Q TV + + D NDNSP F T Y YV L + L V D D+G NA+V LSI K G+I P + DR++QS
Sbjct: 169 IEDINDNAPLFQSTVINISIPENTAINNRYPV-PSAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPV--FKDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIH-FSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDG---SATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITVTDRDADLNGKVTCY-TDHDVPFRLKPVFNDQFLLETAAPLDYETTRE-------YAIKIVASDSGKPPLNTSAMVLIKIKDENDNAPVFPQPEIQLSIPENNDPGTQL---------IKITATDADSGSNALIIYSLGPDAPDGFNIDPRSGILSVSKRLDREKQEKYSFTVIARDNGSNPLQSNVTVK----LIVQDQNDNSPAF-------THAEYNFYVPENLPLYGTVGLITVTDADAGDNAIVTLSIINGKDNFIIDPKTGVIKPNITFDREQQS 677 HSP 4 Score: 84.3445 bits (207), Expect = 4.218e-16 Identity = 93/370 (25.14%), Postives = 155/370 (41.89%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH------NGMLQSVAVLDREEKEEYKLTLIAIDG--TPDVQIRHTVTGSVVIFLNDLNDNSP---------------IFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIK---PGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
I +I D+NDN P F + SI E++ I A D D G+N I H ++ ++ + G+ L+V Q+LDR + F + + V D G P S+ + + + D+N+ PVF S VPE+ P ++ + +D D G NAQ+ + + I+ H G++ LDRE +KL ++A DG TP +V++ + D+NDN P + N PL TK++ + V D+D+ N V P + P F+ D+ ++ L E + + ++ D G+PP ++S + I I D +P
Sbjct: 165 IRFLIEDINDNAPLFQSTVINISIPENTAINNRYPVPSAFDPDVGING--IQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETK-DTFVMKIKVEDGGNPPKSSTAILQVTVSDVNDNRPVFKDSEVEVNVPEN-------APMGTSVTQLHATDADLGSNAQIHFSFSNQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPS-------RATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIAL----------ITVTDRDADLNGKVTCYTDHDVPFRLKPVFN---DQFLLETAAPLDYETTREYAIKIVASDSGKPPLNTSAMVLIKIKDENDNAP 504 HSP 5 Score: 52.373 bits (124), Expect = 2.777e-6 Identity = 61/277 (22.02%), Postives = 123/277 (44.40%), Query Frame = 2
Query: 1676 IEITINLIDINNCPPVFNQSTFHFTVPEDPS--DHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKF-----QISHNGMLQSVAV---LDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAP----YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQP-------LSPKNMVHFNESKEKINKEMIVITI 2440
++I + DIN+ P+F + + ++PE+ + + P VP + D D G+N + ++++F + + V LDRE K+ + + + DG + T + + ++D+NDN P+F ++ + V + + L D D G+NA + S I+P +F+ID + + + L E +HKLIV+ D P +++ + +T ++D+ P ++P N +N ++ +IT+
Sbjct: 163 VKIRFLIEDINDNAPLFQSTVINISIPENTAINNRYP-VP--------SAFDPDVGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDRETKDTFVMKIKVEDGG---NPPKSSTAILQVTVSDVNDNRPVF-KDSEVEVNVPENAPMGTSVTQLHATDADLGSNAQIHFSFS-NQISPATKRHFAIDSSTGLITVKQPLDRESNPVHKLIVLASDGSATPSRATVIVNVTDVNDNVPSIDTRYIMNPVNGTVLLSENAPLNTKIALITV 425
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:103034658]) HSP 1 Score: 252.677 bits (644), Expect = 4.531e-69 Identity = 227/774 (29.33%), Postives = 356/774 (45.99%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD----------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLI---IYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFP-------LPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQI---------TIDDSQPL----SPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G P + + I+ + I DVNDN P F Y L EN + + + + A+D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP + T+IINI D ND +P I + K L+D + E+ ++ PI V V D D+G NG C ++G F L + + Y L D E I D G PSL+S+ + V + D+NDN P F+ S E++ G V V ALD D G N+++ Y + + N +F + +G++ VN LDR E + V+ D G P + + + + D N+ P F Q F F V E+ + P +G + V D DKG NA+++L I++ F I +N G + S DRE+K Y + A+DG + T +V +F+ D NDN P FP LP + + VR + D D+G NA + SI G F ID D + L KL+ +H G+H+L+V D G P +S++ + + T+ D+Q +P N + + K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 131 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDGAESSVRRLGSASTDAHSGKRRFDDAQSRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPARSSQAILRVMITDVNDNSPRFEKSVYEADLPENSSPGAPI-LQLKAMDADVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREEVSQL--RFTVMARDRGQPPKTDKATMIINIKDENDNVPNIDIRKIGRIYLRDGVANVAEDVVVDTPIALVQVSDRDKGPNGVVTCTVVGDVPFQLKPASEIEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDINDNPPIFTKSTVEVSFPENNAPGERVATVVALDADSGKNAEIFYSLDS--SVNGIF--SIDADSGDIRVNTILDR-EQTERYEFKVIAKDKGVPVMQGSATVVVLVADKNDNEPKFMQDVFTFYVKENLQPNSP-------VGMVTVMDSDKGQNAEMSLYIEEEEEIFSIENNTGTIFSTVAFDREQKTTYSFRVKAVDGG---DPPRSATATVSLFVMDENDNPPSV--TFPINSSYTLLPPSSNIRTVVR----TVIATDTDTGVNADLSYSIIGGNPFKLFEIDPDTGVISLVSKLEQKHFGLHRLVVQVNDSGVPSQSTTTLVHVYVNETLSNSTVVDAQIAKSLGTPLNADIAGDPNYDLGKQRLSIAIGVVSGIMTVILIILVVVMARYCRPKNK 879 HSP 2 Score: 131.724 bits (330), Expect = 1.352e-30 Identity = 161/605 (26.61%), Postives = 265/605 (43.80%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYK--------------HSVSNTDSVKRHF-------------AINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVN-QHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA------LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ + ++ S KR F ++T+GE +LI D SY + D G PA SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE+ + T+ D G P T + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P IE + N H LD E ++V++V D G P+LS+ + + + DIN+ PP+F +ST + PE+ + P R + + D D G NA++ ++ ++N F I + +G ++ +LDRE+ E Y+ +IA D G P +Q T VV+ + D NDN P F ++ + YV+ L + V D D G NA ++S+ FSI+ + ++ E + + V D G PP+S++ + + + D
Sbjct: 129 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDGAESSVRRLGSASTDAHSGKRRFDDAQSRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPARSSQAILRVMITDVNDNSP--RFEKSVYEADLPENSSPGAPILQLKAMDADVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREEVSQLRFTVMARDRGQPPKTDKATMIINIKDENDNVPNIDIRKIGRIYLRDGVANVAEDVVVDTPIALVQVSDRDKGPNGVVTCTVVG-DVPFQLKPASEIEGDMNKKKYFLHTSAPLDYEAVQEYNVVIVAVDSGSPSLSSNNSLIVKVGDINDNPPIFTKSTVEVSFPENNA------PGER-VATVVALDADSGKNAEIFYSLDSSVNGIFSIDADSGDIRVNTILDREQTERYEFKVIAKDKGVPVMQGSAT----VVVLVADKNDNEPKFMQDV-------FTFYVKENLQPNSPVGMVTVMDSDKGQNA--EMSLYIEEEEEIFSIENNTGTIFSTVAFDREQKTTYSFRVKAVDGGDPPRSATATVSLFVMD 704
BLAST of Protocadherin vs. Ensembl Cavefish
Match: pcdh7a (protocadherin 7a [Source:ZFIN;Acc:ZDB-GENE-120206-1]) HSP 1 Score: 248.825 bits (634), Expect = 1.553e-68 Identity = 204/719 (28.37%), Postives = 329/719 (45.76%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVD-------LDR----------------------------XXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDIT------IFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL----------AIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY-----KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P +P P+ LS+ EN IGTL+ +P A D +DR ++ ++ +S+ F+L T D + P+L +K +DRE D ELV+ + D G+PP + + ++ + I DVNDN P F Y + EN + + + V A D D G G++ Y + T+SV+R ++ +G + ++ +D + ++L F V A D GQP + TVI+N+ D ND +P++ + K + + + EN ++ P+ V V D DQG NG C ++G F L + + L D E TI D G PSL+S+ + V +VD+ND+ PTF+ E++ G V V A D D G N+++ Y + DP + N F ++ NG++ LDR E + V+ D G P+L + + + D N+ P F Q F F V E+ + P +G + V+D D+G NA+L L A F I +N G + S A DRE + Y + A+DG + + T +V +F+ D NDN+P + P SY R + + D D+G+NA + ++ G F I + L L+ H+G+H+L+V D G P ++ + + I++S
Sbjct: 138 DVNDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIDRYELVQDSRDQRRPASATMPAGINNGAGDRRRGQEAGSVPAGRSNVFELQVADTPDGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVAITDVNDNSPRFERAVYEAEMGENTPPGTPV-LQVRASDRDIGVNGQVEYVFGAA-TESVRRLLRLDEASGWLSVLHRIDREEVSQL--RFTVTARDRGQPPRTDRATVILNVRDENDNVPVVEIRKIGRILVRDGAAMVPENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGENRNKKKFFLHTSALLDYEATRDYTVTIVAVDSGSPSLSSNSTLMVRVVDINDHAPTFAQSLVEVHFAENNAPGERVVTVVAADADSGKNAEIAYSL-DP-SVNGAF--YIDADNGDIRATGALDR-EQRERYEFRVIARDKGSPSLQGSATVVVQVTDRNDNAPKFVQEVFTFYVKENLLANSP-------VGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQELFSIENNTGTIFSAASFDRESRSTYTFRVRAVDGG---EPPRSATATVSLFVTDENDNAP----SVTAPANESYTLLPPASGARTVVRTVMASDGDAGSNADLRYALVGGNPFQLFEIGPSSGVITLAEPLERRHRGLHRLVVRVNDSGVPSLCATALVHVFINES 833 HSP 2 Score: 139.428 bits (350), Expect = 4.224e-33 Identity = 162/639 (25.35%), Postives = 268/639 (41.94%), Query Frame = 2
Query: 695 IQILDVNDNYPTFSTHKYIISLRENFQLNSL--LPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFA-----INSTNGEIR-------------------------------LIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPA--------TSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQ----HLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN-KFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA------LFVEDKDSGANAVVDLSI--------KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
I + DVNDN P+F + +S+ EN + +L LP +A D D G G Y+ + D + A IN+ G+ R LI D SY V+ D G P SS + + I DVND P +++ + + EN P++ V D D G+NGQ ++ G + L + + L H+ DRE+ + T+T D G P T + + + D NDN+P + + + E+ + T V V+ D+D+G N + + PF ++ G + H LLD E ++V +V D G P+LS+ + + ++DIN+ P F QS E+ + P R + +A +D D G NA++ ++ ++N F I + NG +++ LDRE++E Y+ +IA D G+P +Q + +VV+ + D NDN+P F + + YV+ L+A + V D D G NA + L + G FSI+ + ++ E + + V D G PP+S++ + + + D +P NES
Sbjct: 134 IVVTDVNDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIDRYELVQDSRDQRRPASATMPAGINNGAGDRRRGQEAGSVPAGRSNVFELQVADTPDGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVAITDVNDNSP--RFERAVYEAEMGENTPPGTPVLQVRASDRDIGVNGQVE-YVFGAATESVRRLLRLDEASGW-LSVLHRIDREEVSQLRFTVTARDRGQPPRTDRATVILNVRDENDNVPVVEIRKIGRILVRDGAAMVPENVLVDTPVALVQVSDRDQGENGAVTCTVVGD-------VPFTLKPAGENRNKKKFFLHTSALLDYEATRDYTVTIVAVDSGSPSLSSNSTLMVRVVDINDHAPTFAQSLVEVHFAENNA------PGERVVTVVA-ADADSGKNAEIAYSLDPSVNGAFYIDADNGDIRATGALDREQRERYEFRVIARDKGSPSLQ----GSATVVVQVTDRNDNAPKFVQEV-------FTFYVKENLLANSPVGMVTVTDADEGENAELCLFVEEDEEEEEAGGRRQELFSIENNTGTIFSAASFDRESRSTYTFRVRAVDGGEPPRSATATVSLFVTDENDNAPSVTAPANES 740
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: pcdh11 (protocadherin 11 [Source:ZFIN;Acc:ZDB-GENE-140106-21]) HSP 1 Score: 213.001 bits (541), Expect = 2.846e-57 Identity = 205/755 (27.15%), Postives = 346/755 (45.83%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXX---XXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-----HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKD----ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHK-GFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS-DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVE-----DKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPK-----------------SSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKC---RKKA 2512
D+NDNAP + P+ +S+ ENA G F I PA D D + S F+L+ T + + P L ++ S+DRE E+ + D GSPP +G ++ I + D NDN P F + + + EN + + + + + A D D+G+ ++ Y+ + KR F ++ +G + + L+ + Y +++A D G + ++ TV + + DVND P I + + I I E +++N P+ ++V D D G NG C++ + F L + L+ Y L + D E + I D G SL+ + +T+ ++D NDN P F+ P S+ E++ IG + V A D+D N++++Y + D T M P G + + + LDR +S ++ D G P L + +N++D+N+ P F+ + F F V E+ VPK +G + V+D D+G N ++ L+I DN F I +GM++S DRE++ Y L + A DG V+ + T VVI + D+NDNSPI P+ +YK V L V D D+ NA + I G F ID ++ L L H G+H+L+V D G + ++ IE I PL ++ F +++ NK +++ + + +AL + +++ +C R+K
Sbjct: 145 DINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREERQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHV-VQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREE--SPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQL---KKLTYPNQYLLETRETLDYETKNEYVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITVSATDRDMDKNAEMVYFLGPDAPTMFHMDP-----ETGIISLTEQLDREKKAN-YSFTILAKDQGIPVLEGNATVIVNVLDVNDNRPRFSLAEFDFYVNEN-------VPKHSTVGMVTVADSDEGENGRVRLSILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVR---SSTVKVVIHVMDINDNSPIV---LMPPSNTTYKFVVPRTLPGTIVTEVSAVDNDAEINAELRYHIVGGNPHNLFHIDPVIGNITLMEPLTETHHGLHRLVVRVSDIGIAVQHHAVALVHVFVNETLENATYIEWLIAGSLQTPLD-TDVAGFGRREQEDNKVLLLAAVLAGVLGVALIVLLGVLVHRCYCNRRKG 873 HSP 2 Score: 110.153 bits (274), Expect = 8.054e-25 Identity = 164/599 (27.38%), Postives = 259/599 (43.24%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKR-HFAINST-NGE----IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDL-------LFK--QNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSM-----PATS-FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQM----FP-PFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDP--SDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYV-----RHELIALF-VEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
+ I + D+NDN P F+ +S+ EN PI A D DS G Y+ S+ +V ++ T NGE + + KSLD + Y + A D G P S S + IN+ D ND P+ +++ ++ I EN+ + +V + D D G N + L G LF+ QN + + L+ +RE+ I D G + ++ +TV + DVNDN PT + P I E S + V + D D G N + +I +P Q+ +P +L+E+ + LD E + V + +D G +LS + +TI L+D N+ PVF + T+ +VPE+ HL V + +D D NA++ + D F + G++ LDRE+K Y T++A D G P ++ TV +V+ D+NDN P F + + YV +H + + V D D G N V LSI FSID + ++ N E + + L V D G P +SS++++ I + D SP
Sbjct: 139 VRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQ-PANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKSLDREE--RQLYEMNLRAVDGGSPPHSGSAVLRINVTDTNDNSPV--FDQAEVNVEIPENSPVGTHVVQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLL-----NREESPVYRIIILATDKGPEPVPATATVTVTVTDVNDNSPTIEIRDIVAPVNGVIYISEASHVNLPVALITVSDPDIGANGAVTCYIYNPEVPFQLKKLTYPNQYLLETR------ETLDYETKNE-YVVQIKAADAGATSLSRTMSVTIKLLDSNDNAPVFTEPTYKVSVPENNVIGKHLITV---------SATDRDMDKNAEMVYFLGPDAPTMFHMDPETGIISLTEQLDREKKANYSFTILAKDQGIPVLEGNATVIVNVL----DVNDNRPRF-------SLAEFDFYVNENVPKHSTVGMVTVADSDEGENGRVRLSILGTDNRQLFSIDPESGMIRSNVGFDREQRHYYVLEVQATDGGEPVRSSTVKVVIHVMDINDNSP 700 HSP 3 Score: 65.0846 bits (157), Expect = 7.426e-11 Identity = 58/232 (25.00%), Postives = 104/232 (44.83%), Query Frame = 2
Query: 1676 IEITINLIDINNCPPVFNQSTFHFTVPED--PSDHLPLVP------KPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLN--DLNDNSPIFHR---NFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAP--------YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRG 2308
IE+ IN+ DIN+ P F +VPE+ P+ P + + + D + L++ + N ++ + + +S LDREE++ Y++ L A+DG +GS V+ +N D NDNSP+F + N +P +V + L D+D+G+NA V + F +D++ V +N L E ++++I++ D+G
Sbjct: 137 IEVRINVEDINDNAPAFAAPVLTVSVPENAPAGKRFPIQPANDPDSEANGVRRYELLPSDPATVSAFELSVTETANGEKVPYLVVRKS---LDREERQLYEMNLRAVDGGSPPH-----SGSAVLRINVTDTNDNSPVFDQAEVNVEIPENSPVGTHV----VQLHASDRDAGSNAEVVYRLGTSTGGAGSGQGGKRLFRLDQNSGLVTVNGLLNREESPVYRIIILATDKG 356
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008517.1 (pep scaffold:Pmarinus_7.0:GL476786:43429:129410:1 gene:ENSPMAG00000007697.1 transcript:ENSPMAT00000008517.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 193.356 bits (490), Expect = 2.390e-50 Identity = 166/599 (27.71%), Postives = 275/599 (45.91%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLL-PINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIY---QLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPA-LSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN--INKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+ + S+DRE +L + D G I+TI + D D PTF+ Y + EN +L+ ++ S +D ++ + + + + D + F+I + G I ++D + + Y VVA+ G ++ +V + + DVN+ P+ +++ +++I E+ +N V D D G NG+ + IG F I+ QL +++ DRE T++ D G+ L+SS + V ++DVNDN P F+ + F E +G++V V+A D D G N + Y P+ ++ ++ + + L R FS VV +D GRP L ++ + + + D+N+ PP F +S + +V E S+ L+ + SD D+GVN L AI + KF + + G + + LDREE Y L + A D GT + TV V+ D NDN P F + L V LI L D+D+G + V +I G F+IDR SV L R+L E Q +++L V +D GRPP+SS+ + + + D
Sbjct: 610 VSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFENVAPGTLVGSVSASTLDLNA------NVTYLIVSGDQ-RGSFSIEWSGGRIFTANAIDRE--EQAFYQLRVVANSGG---VAGEASVSVLVHDVNNHAPV--FDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVK-YEIGEGNGGEKFG-------IFPDGQLYVRYELDRETREEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSLVGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLL-------RVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVL----DENDNPPRFTESL-LSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAIDRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRD 1174 HSP 2 Score: 182.57 bits (462), Expect = 6.182e-47 Identity = 160/616 (25.97%), Postives = 262/616 (42.53%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKG-FDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQST--FHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI-SHNGMLQSVAVLDREE------KEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
K+ S+DRE + LV+ D GSPPL +T+ + D+NDN+P F +Y S+ EN + V+A D D G G + Y+ + + F +N+ G + SLD + Y V A D G S V I + D D P + + +FEN + VS LD N + +G F + + ++ + DRE++AF + G+ S ++V++ DVN++ P F + SI E P+ + VRA DKD G N ++ Y I + + F I +G L V LDR E +S+ V D G LS+ + + + ++D+N+ P+FN S+ FHF ++ +G + +D D G N +T + + F++ S G + S+ V DRE + +++A DG ++ T V +F+ D+NDN P F ++ VS +L+ + D D G N + +I G F++D + L L E + L+V D G P ++S + + + D P+ F ES
Sbjct: 505 KVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVFYPVQYFASILEN-EPGGTAVTTVTATDPDRGANGTVRYQLTAGDA----ARFQVNAVTGAVSTRVSLDRE--ERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDD--YSFVVFENVAPGTLVGSVSASTLDLNANVTYLIVSGDQRGSFSIEWSGG-------RIFTANAIDREEQAFYQLRVVANSGGVAGEAS---VSVLVHDVNNHAPVFDRASYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEK----FGIFPDGQLYVRYELDRETR-EEYSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQEVGSL---------VGAVQATDADAGSNGGVTYSFEKPQVNFELDSETGRIASLRVFDREALIRQGGAASFSFSVVATDGGRPKPLQDRAT--VQVFVQDVNDNPPQFAKSV-YQASVSESASNLTQLLRVTASDVDEGVNGALRYAINEGNEGGKFTVDASTGQITLLGSLDREETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPPR----FTES 1080 HSP 3 Score: 176.792 bits (447), Expect = 3.822e-45 Identity = 183/689 (26.56%), Postives = 303/689 (43.98%), Query Frame = 2
Query: 377 DLNDNAPHWPKP--IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTD--DEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIIS---LNKSLKDITIFENNNLNEPIVDVSVHDLDQ-GINGQFNCFLIG--HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIV-DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVV---VSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI-----NKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLP--TKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
D+NDNAP +P+P +E++ E+A +G + AVD D N + K S + +P + F L +DRE N L + D GSP G + + + D NDN P F Y S+ E+ P+ + D G L+ + G + + LD+++ + Y+ + A D G P LS T +I ++DVND P I L + + ++ E+ V+V D D NG+ + ++G +G +L + L + ++ + + DRE+ TI D G P S+ V+ V DVND+ P F++ A + ++ E +P G+ V V A+D D GLN++L Y I + N + + ES G + + +DR E+ S +V+ D G + +T+ L+D+N+ PP+F Q+ + T E+ L +V ++ +D D G N + ++ F++ S G + ++ LDREE EEY L + A D G+P + T V + + DLNDN P+F +P+ + E + + D D GAN V + G A F ++ +V L E + +++L V D G S + IT+ D+Q P
Sbjct: 15 DVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRD-VGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREANPSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDS------PVGAALRDLLHRGRGPLAVP--------------FDPKTGMVSTRQPLDFEARRQ--YTLSLRAADGGNPPLSGRATAVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVAS--QLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVKDVTAMDADSGLNAKLRYSIV---SGNDLGWFSVDESTGLVTTDGKVDR----EVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVATAVENSLPGLFVV-------SVSAADSDLGENGTVRYNFDPDMPAQYREMFRLDSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLG----STAKVTVVVGDLNDNHPVF---YPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAA-RFQVNAVTGAVSTRVSLDREERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPP 656 HSP 4 Score: 167.548 bits (423), Expect = 2.427e-42 Identity = 171/675 (25.33%), Postives = 293/675 (43.41%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENF----QLNSLLPINVSAVDCDSGNFGKLSYKHSVS-NTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQF----------NCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGI---PSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS-----DPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLT--LAIKDNINKFQISHNGMLQSVAV---LDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE---LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKD 2302
D+NDN P + P +EL + EN G + A D D+ + + F + + L+ +DRE L + +D + +++ + D NDN P FS H Y + E+ + + V A D DSG FG+++Y + S ++D F ++ G + + + LD +S Y A D G L+++ + +N++D ND P + N SL + E+ ++ +S D D+G+N + F +G+ G QL DRE+++F + D L+S+ +++I+ DVNDN P F+ P ++ + E SP+G VV V+A+D D G NS + Y ++ PF + + G + + + LDR + +++ V+ D GRP L++ + + + D N+ P F + + + ED P + ++ D D+G N +L +A D F++ + +L ++AV LDRE Y+L + A DG + + T SV + L+D+ND SP F + P V +E + ++ + D D G++ V + G FS+ D V L R L E Q H LI+ D
Sbjct: 1508 DVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVV-------DAASGVLRASRRLDREERASYLLTVRASDGTH---ATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRES--RACYVLRARATDGG--GLAATARLYVNVLDANDNAPSVQ-NDSLA-AEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDG---------------QLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAFTSPRSALAP-EDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREAR-QSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPRFPRREYEAAIAEDE-------PPGTEVLRLSAWDPDEGANGELRYDIASGDPTGDFRL--DPVLGTLAVARPLDRERTASYELAVRARDGGGPAR---SDTASVRVTLSDVNDCSPAFQLS---PYTVHARENTQGPPVLILQVVARDDDLGSSGQVTYAAAGGNDGGAFSVSPDGH-VHLLRSLDREAQPQHVLIITATD 2133 HSP 5 Score: 159.844 bits (403), Expect = 5.979e-40 Identity = 177/625 (28.32%), Postives = 283/625 (45.28%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFV--VVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING--QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF-SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTG--SVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQ---SVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT---IDDSQPL--SPKNMVHFNESKE 2407
LK+ S +DRE L IL +D+G P + + + + DVND+ P F+ Y +L E S + +V+A+D DSG KL Y VS D F+++ + G + +D E++ S V + A D G ++ T++ + ++DVNDE P+ + K + T EN+ +V VS D D G NG ++N + +F+ D + ++ DRE+ + D G P L S+ +TV++ D+NDN P F P F SILE+ P GT VT V A D D G N + Y ++ F + + G + LDR + ++ + V D G + +TI + D + PP F + + F V E+ V +G ++ S D N + D F I G + + +DREE+ Y+L ++A G V G SV + ++D+N+++P+F R ++ E V ++ DKDSG N V I G F I D Q +L+R+ + E + L V D G P SSS+ + +T ++D++PL S + HF E +E
Sbjct: 292 LKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPRFALSAYAAALSEGAPAGSYVK-DVTAMDADSGLNAKLRYSI-VSGND--LGWFSVDESTGLVTTDGKVD----REVASSVVLNISAQDQGAQPKTAYTSLTVTLLDVNDEPPLFTQTKYVA--TAVENSLPGLFVVSVSAADSDLGENGTVRYNFDPDMPAQYREMFRL---DSLTGKVTTLKSLDREELEEYPLVVQAQDRGSPPLGSTAKVTVVVGDLNDNHPVF-YPVQYFASILENEPGGTAVTTVTATDPDRGANGTVRYQLTAGDAAR-----FQVNAVTGAVSTRVSLDR-EERAVYQLQVTALDGGHLRARSPAIVTITVADAQDTPPTFARDDYSFVVFEN-------VAPGTLVGSVSASTLDLNANVTYLIVSGDQRGSFSIEWSGGRIFTANAIDREEQAFYQLRVVANSG--------GVAGEASVSVLVHDVNNHAPVFDRA-SYEVSIAEDEPVNSRFFSVRATDKDSGKNGEVKYEIGEGNGGEKFGIFPDGQLYVRYELDRETREE----YSLTVSAMDTGVEPLSSSVTVNVTVLDVNDNKPLFNSSSYVFHFCEEQE 876 HSP 6 Score: 141.354 bits (355), Expect = 3.089e-34 Identity = 131/451 (29.05%), Postives = 205/451 (45.45%), Query Frame = 2
Query: 641 ILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQ-LNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG---HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF-SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPP---FLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHG------RPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-SHNGMLQSVAVLDRE 1936
++ TD G P PL + + + DVNDN P F+ Y S+ E+ L LL V+A D D G G L Y + N F ++++ G+I L+ SLD + SY+ VV A D G L++S TV + ++D ND P +SL + E+ + E ++ ++ D D G +G ++ H F + D + + D E + ++ D G P +S+ ++ V + D NDN P F +P F SI+E+ PIGT V V A D D +N +L Y I+ + FPP F I+ +G + +DR + G +F V V +D R AL N +T+ + D N+ P F T D L +G + SD D+ NA + A+ D F++ G++++ LDRE
Sbjct: 941 VVATDGGRPKPLQDRATVQVFVQDVNDNPPQFAKSVYQASVSESASNLTQLL--RVTASDVDEGVNGALRYAINEGNEGG---KFTVDASTGQITLLGSLDRE--ETASYTLVVSATDSGTSPLAASCTVAVQVLDENDNPP--RFTESLLSVDALESTRVGELLITLTASDEDTGPSGDVRYAIVAGNTHATFAI-------DRSTGSVFLARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAF-LPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIA------RQFPPGAHFTIDPESGEICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKN---VTVLVTDENDNAPRFVTPTAILV------DGL-RAAAGSVVGTLQASDPDEAENAAVRYAVTGGDAAILFRLDRRTGIIETSTELDRE 1358 HSP 7 Score: 134.806 bits (338), Expect = 3.480e-32 Identity = 127/479 (26.51%), Postives = 211/479 (44.05%), Query Frame = 2
Query: 995 QPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILE-HSPIG----TVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK--DNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP---------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+P +SS V I++ DVND P+ ++ + ++ + EN E I +S D DQG N L G +G ++ D L A + DRE+ A T+ D + + ++V + D NDN P FS A SF + E +P G V+ V A D D G ++ Y ++ ++ F + G L V + LDR + + +D G L+ + +N++D N+ P + VPED P ++ I+ +D D+GVNA+L +I D +F + ++G L LDRE + Y L + D R + V + L D+NDN+P F P V + + D DSG N+ V+ ++ G F+++ V+L R+L E + + L V+ D+GRPP +S+ + +T+ D+ +P+
Sbjct: 1493 RPPMSSFNQVEISVEDVNDNPPVFAVPE--MELEVEENTGEGEVIFTLSATDADQGQNALVTYSVLSGSEGAFVV------DAASGVLRASRRLDREERASYLLTVRASDG---THATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRA-CYVLRARATDGG--GLAATARLYVNVLDANDNAPSVQNDSLAAEVPED-------APPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDGQLSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTDVNDNAPAF--TSPRSALAPEDSPVGAVVATVQAVDPDSGRNSYVEYALATDGEEGGGGAGAGPGPFALNTVTGEVRLVRELDREARQSYALTVLAVDKGRPPLTSTATLAVTVGDANDNAPR 1948 HSP 8 Score: 102.834 bits (255), Expect = 2.543e-22 Identity = 168/690 (24.35%), Postives = 277/690 (40.14%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRE-TNDRIELVILLTDSGSPPLTGEGI---ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSG-NELSYSFVVVAHDHGQPALS-SSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSV-HDLDQGINGQ--FNCFLIG-HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGI-----PSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRN-IGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-------NGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLN--DLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGR-PPK--SSSIEIQITIDD 2356
D NDN P + P + SI EN IGT A D D + ++ P E + + IDRE T E+ + TD P T +T+ + D NDN P F T I+ S++ + A D D + Y +V+ D+ F ++ G I LD +SG + V V P + T+I N + N LP + I + + + P + + H LD GQ F L+G +G ++ + + + L A+ F F+ + D G P ++S + + + DVNDN P F++P + E++ G V+ + A D D+G N+ + Y + + F+++ ++G L ++ LDR + ++ V + G A ++ + + D N+ P F++ + F V ED + P R IG + D D G ++T A+ + + G L LDRE + Y L A DG + + +++N D NDN+P N L +V L+ + D D G NA ++ SI G F++ D Q + + R L E Q + L+V DR R PP SS++ + + + D
Sbjct: 1174 DFNDNPPAFLPGDVFASIMENIPIGTRVITVTARDPDADVNGELHYSIARQFPPGAHFTIDPESGE-----ICTAAEIDREVTGGLFEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSVVG-TLQASDPDEAENAAVRY--AVTGGDAAI-LFRLDRRTGIIETSTELDRESGHGAFTLEVVAVEAKAAAPRTQRAENTIIANSMTFNHPLPRFPQDYE-SPINLLQGQTIPMPSSYLFLRHHLDWEPEGQLVFFTLLLGVTRGHGVINPLDAPWRVSFDLTARCMF----IVFSSLLSSLRDNGAGSFIRPPMSSFNQVEISVEDVNDNPPVFAVPEMELEVEENTGEGEVIFTLSATDADQGQNALVTYSV-----LSGSEGAFVVDAASGVLRASRRLDR--EERASYLLTVRASDGTHATDARLSVAVR--DANDNSPRFSRHAYSFDVAEDAA---PDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDG-------GGLAATARLYVNVLDANDNAPSVQ-NDSLAAEVPEDAPPGTSLLRISATDDDEGVNAELEFSISSGDPEGRFAVGNDGQ-LSVARALDRERQSFYNLVVRVSDRARHPPARLSSAVRVSLILTD 1828 HSP 9 Score: 90.8929 bits (224), Expect = 1.138e-18 Identity = 148/616 (24.03%), Postives = 242/616 (39.29%), Query Frame = 2
Query: 593 LKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPA---LSSSTTVIINIVDVNDELP-IISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIV----DVNDNLPTF----------------SMPATSFSILEH----SPIGTVV--TKVRALDKDEGLNSQL--IYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALS--NQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR---NFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPY----FSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRG 2308
L +D ET L + D G PP + I+ + + D NDN P F S+ EN + + + I V+A D D+ G+L Y S++ HF I+ +GEI +D + L + V A D P S+ V + + D ND P ++ L D ++ + + D D+ N + G +LF+ + II + DRE A+T + +Q I+ N LP F MP +S+ L H P G +V T + + + G+ + L + +S T MF ++ + L L D S I RP +S NQ+EI++ D+N+ PPVF V E+ + I ++ +D D+G NA +T ++ + F + + +G+L++ LDREE+ Y LT+ A DGT H + + + D NDNSP F R +F + + +I + D DSG V ++ P + + F + ++ + R L E + + L D G
Sbjct: 1136 LARRLDFETQRLYRLNVSAEDGGRPPRSSATILVVHVRDFNDNPPAFLPGDVFASIMENIPIGTRV-ITVTARDPDADVNGELHY--SIARQFPPGAHFTIDPESGEICTAAEIDREVTGGL-FEVTVRATDKAIPVHTRRSALKNVTVLVTDENDNAPRFVTPTAILVDGLRAAAGSV---VGTLQASDPDEAENAAVRYAVTGGDAA-ILFRLDRRTGII---ETSTELDRESGHGAFTLEVVAVEAKAAAPRTQRAENTIIANSMTFNHPLPRFPQDYESPINLLQGQTIPMP-SSYLFLRHHLDWEPEGQLVFFTLLLGVTRGHGVINPLDAPWRVSFDLTARCMF----------IVFSSLLSSLRDNGAGSFI-------RPPMSSFNQVEISVE--DVNDNPPVFAVPEMELEVEENTGEG-------EVIFTLSATDADQGQNALVTYSVLSGSEGAFVVDAASGVLRASRRLDREERASYLLTVRASDGT------HATDARLSVAVRDANDNSPRFSRHAYSFDVAEDAAPDGKTTRAVIGTVLAGDADSGPFGEVTYALAPSEDSDWADGAFGLHPVTGALNVTRPLDRESRACYVLRARATDGG 1707 HSP 10 Score: 75.8702 bits (185), Expect = 4.041e-14 Identity = 87/357 (24.37%), Postives = 152/357 (42.58%), Query Frame = 2
Query: 1355 ITVIIVDVNDNLPTFSMPAT-SFSILEHSPIGTVVTKVRALDKDEGLNS--QLIYHISDPRTTNQMFPPFLIESNG--NLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF--PLPTKVSYKEYVRHELIALF--VEDKDS-GANAVVDLSIKPGIIAPYFSIDR----DRQSVKLNRKLKSEHQGIHKLIVIGKDRGRP-PKSSSIEIQITIDDSQPLSPK 2377
+ V++ DVNDN P+F P + E + +G V A+D+D G N Y I ++ PP + +L LDR + +++ V D G P ++++ + + D N+ PP F + + +V ED P+ R++ + + LA+ + GM+ + LD E + +Y L+L A D G P + R T VI L D+NDN P + P S E +A V D DS AN + +SI G +F + + +K+ +L E ++ L ++ D G+P +S++ + + ++D +P+
Sbjct: 9 VRVVVGDVNDNAPSFPEPGVMEVAFKEDAAVGRQVLLDTAVDRDVGPNGVNHHAYKIVSGNEEGRLVPPRPVTKRAFLHLATTGPLDREAN-PSYALAVQAEDGGSPRRYGRLQVNVTVQDANDNPPAFEKPAYRASVAEDS----PVGAALRDLLH----------RGRGPLAVPFD------PKTGMVSTRQPLDFEARRQYTLSLRAADGGNPPLSGRAT----AVIQLLDVNDNDPAIRFVYLPPAARSASVDESAAPGTVAALVTVTDADSPTANGELSVSIVGGNERGHFVLHAPGVPGLRVLKVASQLDRERIPMYNLTILASDNGKPVARSATASLVVYVNDVNDHAPR 340
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010725.1 (pep scaffold:Pmarinus_7.0:GL479425:26296:30457:-1 gene:ENSPMAG00000009713.1 transcript:ENSPMAT00000010725.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 180.644 bits (457), Expect = 5.657e-47 Identity = 206/811 (25.40%), Postives = 353/811 (43.53%), Query Frame = 2
Query: 92 RDSITLSVEERFPVNYFVTDLK--NILAI---PLNSSTRFNMLHVHSYFRLSS-SGIISVARQLDCDNDSNLCDKTLEYCMTKLFXXXXXXXXXXXXXXXX------------DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPK-----------------LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTF-STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL----NKSLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPAT--------SFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPF-LIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVF---NQST---FHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL-----AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVR-----HELIALFV--EDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRG 2308
+ ++ V+E V Y + DL+ N+L + P LH S ++ SG +SVA +LD + LC + + C + F+ V + D+ND+AP + P + +SISE+ +G +P A+D D + Q L + L+L+ +DRE EL++ D G+P L+G ++TI ++D NDN P F + + E+ ++ + + + + A D D+G G ++Y H+ + + + ++ T G + + + D + VVVA D GQ + S+S TV + + D ND P+ + + L D + I EN P+V +SV D D G +G + L G +L + + L D E+ ++ D G P L+ + + +VD+NDN P F PA+ S+ E+ P GTVV + A D D G N + + +S+ + F L G L + LDR + + V D G P + + + ++D N+ P F + ST + F V E+ S +G ++ SD D+G NA++ L A D I + G+++++ VLDRE++ +Y+L++ A+D G P + + + V I ++D NDN+P+ P ++VR L+ + V D D+G N I G F ++ D ++ L R + S +G+H+L+V +DRG
Sbjct: 26 QGALLYEVDEEVLVGYVIGDLRQSNLLCVCFFPPAPHVSPLPLHTPSLCIVNELSGELSVALRLDREA---LCMEEPDACRSTGFMHTVQVAAMAKGQGSSNLRLLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLPRAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREAVPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVFVDPPTRPVRITEHSKVGTSV-VQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVRNAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFPTGAELASPNKVQ----FLLKTTRLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMR-YELSVEACDGGSPQRKARAIVRVTVLDENDNAPTFVGVSNSTNCMYQFFVEEETS-------VGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYELSVRAVDSGRPAL----SASCRVSITVSDTNDNAPVITS----PNTNDTWKHVRTFSPAGMLVGVSVTANDIDAGDNGRPLYEIIGGNPKGIFLLNADSGALSLARTVSSLDEGLHRLVVRVRDRG 812 HSP 2 Score: 123.25 bits (308), Expect = 7.639e-29 Identity = 154/625 (24.64%), Postives = 264/625 (42.24%), Query Frame = 2
Query: 686 IITIQIL--DVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH-FAINST-------------------NGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGING----QFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFS--------MPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPP----FLIESNGNLLVNQHLDRLLD---GEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVF-NQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-------HNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL-IALFV-----EDKDSGANAVVDLSIKPGIIAPYFSIDRD------RQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
++ +Q+L D+ND+ P F +S+ E+ + +P+ A+D D+G Y+ S ++ D ++ F++ + + L + LD ++ SY ++ D G P LS S + I +VD ND P+ ++ + + I E++ + +V + D D G NG F+ L L + L+ + K DRE + D G S ++S +TV + D NDN P F +P I+E+ P GT V + D D G + + + P T ++ P FL+++ RLLD + ++V V+ +D G P LS + + I+++DIN+ PVF N ++ V P + + +D D G N +T + + ++ G L LDRE++ Y+L++ A DG +P + R V +V+ D NDN+P F T Y+ +V E + +V D D G NA V L++ + D R V L+R+ + +++ L V D GRP S+S + IT+ D+ +P
Sbjct: 127 LLDVQLLVRDINDHAPAFRAPHLNVSISESEAVGRRVPLP-RAIDPDAGTNSIQHYRISAASGDGLQLGPFSLVESDDDDDGGGVGVDGDGGMGHRALLELREQLDREA--VPSYELLLWGEDGGNPKLSGSVLLTIVVVDANDNAPVF-VDPPTRPVRITEHSKVGTSVVQLRAADPDAGPNGAIAYSFHTKLTSLATQAALHVDGTTGLVTVR--NAEKLDRETMPVHRLVVVARDGGQLSRSASVTVTVELNDDNDNAPVFEVIALQGEYLPDGGVKIVENLPSGTPVVLISVSDPDLGSSGTVDVRLEFP-TGAELASPNKVQFLLKTT----------RLLDYEEAQQYNVSVLAADRGTPKLSKLLNLIISVVDINDNTPVFMNPASIEGDVAVYEVSLRENGPAGTVVLNLLATDADSGPNGAITFTLSELAGGESVAELFSLNMRTGQLTLATPLDREKRMRYELSVEACDGGSPQRKARAIVRVTVL----DENDNAPTFV-GVSNSTNCMYQFFVEEETSVGTYVGTVSTSDLDEGDNARVALNLVREAGPDWIGGAGDTPGGVVRTLVVLDREDRVQYE----LSVRAVDSGRPALSASCRVSITVSDTNDNAP 725
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006996.1 (pep scaffold:Pmarinus_7.0:GL476780:2096:143714:1 gene:ENSPMAG00000006222.1 transcript:ENSPMAT00000006996.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 177.948 bits (450), Expect = 1.832e-45 Identity = 199/728 (27.34%), Postives = 328/728 (45.05%), Query Frame = 2
Query: 383 NDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQF---PK---LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPI-NVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGE--IRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGIN-GQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITV--IIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFL--------IESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRP--ALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK--FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE--LIALFVEDKDSGANAVVDLSIKPGIIAPYFSID-RD---RQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLA 2464
NDN P + P+ +S+ ENA +GT A DLD + +++ +DD +F P + + +++D E R + ++ D G G + I +LDVNDN P F Y+ + REN NSL P+ V A D DS +++Y S+ T + +F+I + G + L ++LDY+ + S ++A D G P L+S+ T I+ + D ND PI N I I EN ++ V+ D DQ GQ + D+ L+ DRE + + D G + + + TV ++DVNDN P + + +I+E++P GT + V A D D N L+Y I P PF I + G L + L+ + + S++V +D G P + +T+ L D+N+ P F + V E +P + + +D D+G N +T ++ + + FQ+ + G++ ++ LDRE Y+L L+A D GTP + T T S+V+ D+NDN+P FH P + VS E V + +I+L D DSG NA + I G FS+ RD R V L+R+ K+ + + + I G R ++++++ + ++D++PL F E +++ V A+I+ V A
Sbjct: 24 NDNRPIFSLPLYNVSVWENATLGTSVVQVLATDLD--------------AGVFGQVSYHFSDDSDKFSLDPASGLISVAAALDFEATPRFTVTVMARDGGGQETAGR--VRINLLDVNDNTPVFQRDSYVGTAREND--NSLTPVVRVRATDEDSPPNNQITY--SILPTSAYSSYFSITVSGGYGVVTLARALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNS--YSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQFRINARSGDITSTTLL-----DREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDIFTVSAADPDLNENGTLVYAIDPPN-------PFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQVLEG-------LPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTP--ALSSTTTLSLVVL--DVNDNAPTFH---PARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGFRDGLVRTVVSLDRETKASYSLVIEAIDNGPAGSRRTGTTTLDVLVLDVNDNRPL-------FLEGSYEVSVPENVTRGAIILQVQA 696 HSP 2 Score: 159.844 bits (403), Expect = 7.935e-40 Identity = 157/580 (27.07%), Postives = 267/580 (46.03%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIIT--------IQILDVNDNYPTF-STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRHFAI--NSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVF----NQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-------KDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF---------HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDR 2221
++ ++++DRE D L +L D G P ++T + + D NDN P F + ++ +RE+ +LL + + A D D+G+ G +S + H+ + T ++ I N + I + D+ F +VA D G P S++ + + ++DVND +PI L+ +++ E + V D D G NGQ F I G D L SD II ++ DRE A + D G P L+ S ++ V++ DVND P F P + S+LE +G+ V V+A + +G N++ Y I+ F + + L+ + L L E F++ V +DHGRP L Q + + ++D+N+ PVF N + + T + +P+V R + +AV D D+G N + + + F+I + +G++ + LDRE + Y L L+A D G P + + T + + L+D++DN P+F +++F +P V + A+ D D GANA+V I G F++ R
Sbjct: 1784 EITTQAALDREATDSYMLTVLSRDGG--PREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTV-LHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIF-LSPGGYAVSVVELGAPGTLVASVWATDADAGPNGQV-TFRIESGGGDKL-SIGPSDGII-RVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAGIGKN-----AFTVHATSGLVTSTRL--LKSYERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNIT------EVMPVV--IRIVEVLAV-DGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRESQAVYSLILLASDQGQP---VSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAV---DADVGANAIVYYFIAAGNEGNKFNLSR 2334 HSP 3 Score: 152.91 bits (385), Expect = 1.031e-37 Identity = 163/628 (25.96%), Postives = 278/628 (44.27%), Query Frame = 2
Query: 377 DLNDNAPHWPKPIE--LSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAF-LPTDDEHQFPKLKL-KSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTF-STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMP--ATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYH-ISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGE---IFSVIVVVSDHGRPALSNQIE-ITINLIDINNCPPVF------NQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLT--LAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAI---DGTPDVQI-------RHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVV 2170
D NDN+P + + + E+A GTL + A D D + + L +E + + K+ +T+ I I+ D GSPP + +++ +LDVNDN P F S Y +S+ E +L+ +V A D D+G G+++++ D +I ++G IR+ + D +Y+ +VVA D G P LS S V + + DVNDE P + ++ +++ E+ ++ + V + +G N ++ + G + K + L+ + + E F T + D+G P L + V ++DVND+ P F +P T +I E P+ + +V A+D DEG N + Y + ++ + F I + ++ R LD E ++S+I++ SD G+P + + + L DI++ PVF F++PE H P N+ D D G NA + +A + NKF +S G+L ++ LDRE Y + + A + TP V + V ++L D+ND P+F N V+ V EL+ L D+D G N++V
Sbjct: 1831 DENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLDVNDNVPIFLSPGGYAVSVVELGAPGTLV-ASVWATDADAGPNGQVTFRIESGGGDK----LSIGPSDGIIRVAPGANIDRETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERP--AFLAPVQTVSVLESLSVGSFVATVKATENYKGHNTKYTYKIAG------IGKNAFTVHATSGLVTSTRLLKSYERFNLTAV-ATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPVVIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTA---RALDRESQAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPE----HSPPGTAVGNVS--GAVDADVGANAIVYYFIAAGNEGNKFNLSRWGLLVVLSDLDREVSPYYAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVF-TNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIV 2434 HSP 4 Score: 148.288 bits (373), Expect = 3.011e-36 Identity = 169/628 (26.91%), Postives = 279/628 (44.43%), Query Frame = 2
Query: 689 ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQ-PA--LSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTF-SMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIE--ITINLIDINNCPPVFNQSTFHFTVPED-PSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQISHNGMLQSVAV---LDREE--KEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGA--NAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPL 2524
+ I+I D NDN P F Y + L E + NV+A D D G+ ++ Y NT + F I++ G + +K+LD++ L Y VV A D + PA L+S+ TV +++ DVND P L I + E I D D G+NG+ +I G + + DL + + + + DRE +AF TI D G P L S+ + V ++DV+DN P F ++PA + S+ E + + +V++VRA D +EG N + S N + G + VN+ LDR E + V + P+ + + + + ++D N+ PVF+Q T+ +PE+ P+ + V G I SD D GVNA L ++ + F I + S+A+ LDRE +LT++ DG R T + + + D+NDN+P F+ + V +I + D+D G V SI G F ID + + E + + L+V+ D+ P ++S E+++++ NE EK++ + A +S A+ + + + + KA P L
Sbjct: 1158 VLIRITDENDNAPAFGAATYEVLLTEGPSTAGVAVANVTASDPDEGDNARVVYAIVSGNTAAT---FGIDNGTGVLTAVKALDFEVSAGL-YLLVVTATDQPRDPARRLTSTATVSVHVADVNDVTPWF-LRSYEGPIDVSEGQP-GPRIATFMASDQDSGLNGELEYSIIDGDPRNEFVISPADGDLRVRRYV---ELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANA-SLSEAAAVLAIVSRVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLN----GPIYASDADFGVNATLAYSLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILVQDGG-----RRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASG-GNDTFGIDESTGLIVTVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQ-------------NELDEKLSFSLAAYQAA--LSEAAVPGTVVVRVAAPQMKAPPKL 1750 HSP 5 Score: 138.272 bits (347), Expect = 3.717e-33 Identity = 160/608 (26.32%), Postives = 262/608 (43.09%), Query Frame = 2
Query: 677 GEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREK--EAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI--SHNGMLQSVAV-LDREEKEEYKLTLI-------AIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISV 2458
G + I +++ NDN P FS Y +S+ EN L + + + V A D D+G FG++SY S DS K F+++ +G I + +LD+++ ++ V+A D G ++ V IN++DVND P+ + + T EN+N P+V V D D N Q ++ + F +S +A+ D EK TI D G P L S+ V + D NDN P F + S +I E+ G V V A D D+ + I + Q F I + +G++ LDR + I V V G + + I L+D+N+ P + + T+ E+ P +I ++ +D D N L AI D N F + +G +++ + LDRE+ + A G+P R T + +V + L D+NDN P F P +V L + D D GAN V S+ + P F +D + +L E ++L ++ DRG P SS+ + + + D +P F+ ++ ++ V +V+IS+
Sbjct: 12 GSARVHITLINENDNRPIFSLPLYNVSVWENATLGTSV-VQVLATDLDAGVFGQVSYHFS---DDSDK--FSLDPASGLISVAAALDFEATPR--FTVTVMARDGG--GQETAGRVRINLLDVNDNTPVFQRDSYVG--TARENDNSLTPVVRVRATDEDSPPNNQITYSILPTSAYSSYFSITVSGGYGVVTLAR-ALDYEKIPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQSPEYGQLSLIYSLEGSTQ----FRINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVEN-------TPGGTDIFTVSAADPDLNENGTLVYAI-DPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSP--PRRATASATVTVLLQDVNDNEPSF-VGLPYALQVLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLVQLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPT----FHPARSAVSLMESVARDSVVISL 587 HSP 6 Score: 126.716 bits (317), Expect = 1.374e-29 Identity = 155/620 (25.00%), Postives = 269/620 (43.39%), Query Frame = 2
Query: 215 SYFRLSSSG---IISVARQLDCDNDSNLCDKTLEYCMTKL-FXXXXXXXXXXXXXXXXDLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPT-DDEHQFPKLKLKSS-------IDRETNDRIELVILLTDSG--SPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIK-SLDYDSGNELSY----SFVVVAHDHGQPA--LSSSTTVIINIVDVNDELP-IISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG---HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEIT---INLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI----KDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID 1975
SYF ++ SG ++++AR LD + + T+ + L + + D NDN+P + + ++I EN G A D D++ Y L+ + + + QF ++ +S +DRE + L++ D G + TG + I +LDVNDN P + Y +++ EN + + VSA D D G L Y D + IN+ +G+IR LD + N +S+ S VV D G P ++S TV + + DVND P + L +L+ + E N + V+ D D+G NG + F L L ++ + DRE A + D G P+L+S+ ++++++DVNDN PTF ++ S++E +VV + D D GLN++L + I+ Q F +G + LDR +S+++ D+G PA S + T + ++D+N+ P+F + ++ +VPE+ V + I + +D D+G+N ++ I +D +S + + LDRE + L + A +
Sbjct: 178 SYFSITVSGGYGVVTLARALDYEK---IPGGTISLTIMALDGGSPPLNSTVTAIVEVFDENDNSPIFDRNSYSIAIPENILAGATVLYVNATDGDQS-------------PEYGQLSLIYSLEGSTQF-RINARSGDITSTTLLDREAVSQYILIVRAVDGGDGNDQKTGIATVNITLLDVNDNDPAWRDLPYAVTIVENTPGGTDI-FTVSAADPDLNENGTLVYA-----IDPPNPFYRINAASGKIRTTGLQLDREDLNPISFASMRSIVVSGADRGSPPRRATASATVTVLLQDVNDNEPSFVGLPYALQ---VLEGLPANSTLFQVTATDPDEGANGNVTYSMTAALPRPDFQLDAATGLITTLV-------QLDREAVAAYQLRLVATDRGTPALSSTTTLSLVVLDVNDNAPTFHPARSAVSLMESVARDSVVISLNCTDADSGLNAELSFFITGGNQDGQFSVGF---RDGLVRTVVSLDRETKAS-YSLVIEAIDNG-PAGSRRTGTTTLDVLVLDVNDNRPLFLEGSYEVSVPEN-------VTRGAIILQVQATDIDEGINGRVWYRIISGNQDGNFLVNVSSGLISRGATPLDRETVALHALQVEAFN 752 HSP 7 Score: 118.242 bits (295), Expect = 4.312e-27 Identity = 154/625 (24.64%), Postives = 264/625 (42.24%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAH-DHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNN-------LNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSP-IGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI------KDNINKFQISHN--------GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIR---HTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLS--IKPGIIAP--YFSIDRDRQSVKLNRKLKSEH-QGIHKLI---VIGKDRGRPPKSSSIEIQITIDD 2356
+++ +DRET L I+ D G+PPL + +++LDV+DN P F SL E + +++ V A D + G +HS ++ + +R F +S G + + + LD + E + V + D+ A S +I+ I+D ND P+ S + + I EN+ LN PI D D G+N L+G L ++ ++ + DRE +T ++ + V ++DVNDN PTF++ + + +LE+SP +GT V V+A+D+D G+ S N F + ES G ++ +D E + ++VV +D P + E+ ++L + + F+ + + + E VP + +A L LAI +D +K Q S N G + + A LDRE + Y LT+++ DG P I + V + + D NDNSP F +V L L D+D+G+N V G P Y I ++ V + K++ + + I ++ D G PP+S++ + + + D
Sbjct: 1340 RVRRYVELDRETQAFYNLTIMAKDMGTPPLNSTLTVGVRVLDVHDNDPVFLNLPANASLSEAAAVLAIVS-RVRASDANEGRNCAALLQHSPTSFCNGERAFYADSQTGLVYVNRPLDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFS--QVTYEAEIPENSPNGTVLTVLNGPIY---ASDADFGVNATLAYSLLGGSSAYFLIDRDRGNV---SMALGQGLDREGIPGGRLELTILVQDGGRRNATVRLGVTVLDVNDNTPTFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTF--GIDESTGLIVTVAPIDYETRPE-YLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSE------AAVPGTVVV-RVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDREATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTLLTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPPRSTTFNLSVIVLD 1945 HSP 8 Score: 85.1149 bits (209), Expect = 6.076e-17 Identity = 86/323 (26.63%), Postives = 152/323 (47.06%), Query Frame = 2
Query: 623 DRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTF--STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK--HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTT---VIINIVDVNDELPII--SLNKSLKDITIFENNNLNEPIVDVS-VHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDY---GIPSLTSS-----------QLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI 1516
+R L + TD G PPL G+ + +++LDVND+ P F + ++++ E + + + V AVD D G G + Y H+ F IN+T+G I ++LD +S + YS +++A D GQP ST V+++ +D N+ + I+ + +I E++ + +VS D D G N F+ G++G K NLS + L+ DRE + Y I P++T+ + + V + D+ND P F+ + + + +G+ + ++ A+D+D G NS ++Y I
Sbjct: 2126 ERFNLTAVATDHGRPPLWGQAGLYVEVLDVNDHRPVFVLPPNGTVVNITEVMPV-VIRIVEVLAVDGDEGQNGAVRYSFLHAGGVGSRDWESFRINATSGIISTARALDRES--QAVYSLILLASDQGQPVSYESTQPLQVVLDDIDDNEPVFIVLPDGGAPYQSFSIPEHSPPGTAVGNVSGAVDADVGANAIVYYFIAAGNEGN----KFNLSRWGL--LVVLSDLDREVSPY-YAIIVKASSNPNWTPAVTTGPEFDPSKDRTLREVRVYLEDINDQWPVFTNHEYTAGVAVDAKVGSELLQLEAVDRDVGNNSIVLYRI 2438 HSP 9 Score: 71.633 bits (174), Expect = 7.904e-13 Identity = 164/707 (23.20%), Postives = 272/707 (38.47%), Query Frame = 2
Query: 605 IDRETNDRIELVILLTDSGSPPLTGEG---IITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPI---NVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLI--KSLDYDS--GNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENN-NLNEPIVDVSVHDLDQGI-NGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI------SDPRTTNQMF--PPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRP-----ALSNQ--IEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK---------FQISHNGMLQSVAVLDREEKEEYKL--TLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEY-VRHELIA-LFVEDKDSGANAVVDLSIKPG-----IIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISDM 2587
+DRE L + + D+ P I+ + ILD NDN P FS Y + EN ++L + + A D D G L+Y S +F I+ G + + + LD + G L + +V D G+ +++ + + ++DVND P + N + + + EN+ + ++ V D D G+ + + I G D + LI+ D E + D P T+S + V + + D +FS+ A ++ E + GTVV +V A L I D R Q + G + LDR + ++ V+S G P L+N+ + +N+ D N+ P F + + + L + + +D D G N ++ + Q + VA D EK + ++A+DG +P R T VI L D+NDN PIF P VS E L+A ++ D D+G N V I+ G I P I R ++R E + + L+V+ DRG PP S S +++ +DD P + V T++V+ S L++GSF+ V K Y++ + K A ++ S +
Sbjct: 1455 LDRERVAEYRLTLTVRDNPDNPSYARKDSDIMIVTILDENDNSPVFSQVTYEAEIPENSPNGTVLTVLNGPIYASDADFGVNATLAY----SLLGGSSAYFLIDRDRGNVSMALGQGLDREGIPGGRLELTILV--QDGGR--RNATVRLGVTVLDVNDNTP--TFNVTSQTAHVLENSPAVGTSVIVVKAMDRDLGVCDAGTVRYSIASGGNDTFGIDESTGLIV----TVAPIDYETRPEYLLMVVATDQAPPFHTASCELRVSLQNELDEKLSFSLAAYQAALSEAAVPGTVVVRVAAPQMKAPPKLPLPLAILVQKWHEDKRHKQQESDNAELIAALQGEITTQAALDR--EATDSYMLTVLSRDGGPREAIAVLTNKPGAYVYVNVTDENDNSPEFEAGSATLVEVRESAAPGTL------LTVLHATDRDAGSNGTVSARAHTHTGTRIPPQYILIIQNESGVTIVDVAKADFVEKTSQFILFRIVALDGGSPP---RSTTFNLSVIVL-DVNDNVPIFLS--PGGYAVSVVELGAPGTLVASVWATDADAGPNGQVTFRIESGGGDKLSIGPSDGIIRVAPGANIDR----ETRAAYTLMVVAVDRGNPPLSGSAIVRVLVDDVNDERPAFLAP-------------VQTVSVLES-LSVGSFVATVKATENYKGHNTKYTYKIAGIGKNAFTVHATSGL 2115
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004042.1 (pep scaffold:Pmarinus_7.0:GL479143:9150:31231:-1 gene:ENSPMAG00000003698.1 transcript:ENSPMAT00000004042.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 173.711 bits (439), Expect = 3.448e-44 Identity = 172/607 (28.34%), Postives = 278/607 (45.80%), Query Frame = 2
Query: 656 SGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHG-QPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG--HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKD-NI-NKFQISHN-GMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLS-IKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK--NMVHFNESKEKINKEMIVITIAV 2446
+G P LTG G +T+ + D NDN P F + ++ E+ + S + + V+A D D+G +SY+ + D HF++N + G+I SLD + G E SY V A D G P LSSS T+++ + DVND P LN + + V+ D D G NG L G GF + ++ + + A ++ T+ D G P ++ +TV D + P F+ SFS E P GT +T V A + + YH++ +F + +G + V++ LD + ++V D G P S +++ ++++DIN+ P F+ S F VPE+ PR I + D D G+N Q+ +I D NI N F+++ N G ++SV+ LDRE Y+LT+ A D G+P +H T V+I + D NDNSP F + F V V ++ + D D G NA + S + P + FSI + ++R+L E + + + V D P + S ++ I +DD +P+ ++ E E E +V ++
Sbjct: 1 AGEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVAL-VNATDADAGLNAIISYR--LRGGDG---HFSVNPSTGQIITTASLDRE-GRE-SYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRF-LNAPYVAYAP-SSAPAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGV-------IHAARALQGPRDDLTL-TVRVSDGGAPPRSAVTTVTVRFRDAGE-FPRFAPGPRSFSFREDQPPGTTITVVAA--RSSRRAGPVSYHLASGGNLGDVF--AVDPQSGEVSVHRALDHEYQ-HHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPEN--------TPPRTIVVLTAVDKDSGINGQVDYSIIDGNIGNVFRVNPNSGEIRSVSTLDRENVASYELTVKATDRGSP---TQH-CTVKVLISVTDENDNSPRFTQIF--SAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPSLP---FSIHPSTGEITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSA 563 HSP 2 Score: 164.851 bits (416), Expect = 2.272e-41 Identity = 159/616 (25.81%), Postives = 266/616 (43.18%), Query Frame = 2
Query: 575 QFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMF------------PPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKS--SSIEIQIT-IDDSQPL 2368
Q ++ + ++D E ELV+ DSG PP + + + +LD+NDN P FS+ ++ + EN ++ + ++AVD DSG G++ Y N +V F +N +GEIR + +LD + N SY V A D G P + V+I++ D ND P + + + E+ + P++ VS D D+G N L+ L F + S ++ + +RE + + D P+ T S +T+++ DVNDN P F A E S +V +V A D D+G N Q+ + + R+ + F P +L++ +S +V D GRP LS+ +TIN++ N P F + + V V I ++ D D+ VN Q+ ++ + +F + G L A L + + +T+ A D G P + R T +I + + N +P F + PL + L + D D+G N + SI G + F I R V L +L E + ++ L V D G K+ S + I +T ++D+ P+
Sbjct: 284 QSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTI--VVLTAVDKDSGINGQVDYSIIDGNIGNV---FRVNPNSGEIRSVSTLDRE--NVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFT---QIFSAHVREDAAVGFPVLRVSTLDADEGPNAAITFSLLDPS---LPFSIHPS---TGEITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALVARVSASDADDGANGQVFFFM---RSQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNK------YSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPV-------AATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDVDAGGFLHLRASLAGDAGSIFSVTVEARDRGRPPLSSRAT----AIISVTEENQYAPRFA-HPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVGELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPM 859 HSP 3 Score: 153.295 bits (386), Expect = 8.541e-38 Identity = 150/588 (25.51%), Postives = 261/588 (44.39%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDY------DSGNELS-YSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGH---KGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI--SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRG 2308
++ + ++RE + + +D P T +TI + DVNDN P F Y I E + +L+ VSA D D G G++ + S +F + +GEI ++ L Y SG L+ YSFVV A D G+P LSS TV INIV N P + + I+D+S D D+ +NGQ ++G + FD+ D + L + + + T+ D G P L+S + + + N P F+ P S+ E+ P G+ + +V A D D G+N ++Y I+ + +F + ++G++L+ LD + +++++ V +D G A + ++I++ D+N+ PP+ N S ++ +PE+ P + + D D NA ++ D + G+L + LD E K+ Y+LT+ A + PD H T V + + +N+ P F R + VS V + ++F D+D+G + V + + FS++ + ++ +L E + L VI K+ G
Sbjct: 493 EITVSRRLNREDRSGYAVKVRASD---PAWTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSEGEALV-ARVSASDADDGANGQVFFFMR-----SQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAP--RFLRERYSTPVAATVRAGTRILDMSAVDPDRDVNGQIAYSVVGGNASRRFDV-------DAGGF-LHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSG-LFD--ISRASGDVLLVGELDYETE-KLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPEN-------APSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVLNQKTGVLTTQGFLDYETKQTYELTVRAFN-YPDTF--HYSTAQVHVQITGVNEYFPRFVQREYNF--VVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAG 1045 HSP 4 Score: 135.961 bits (341), Expect = 1.932e-32 Identity = 152/607 (25.04%), Postives = 249/607 (41.02%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSG-SPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIY-----QLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRN-----FPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLK-----SEHQGI----HKLIVIGKDRGRPPKSSSIEIQITI 2350
+S+DRE + L + D G +P L+ + + + DVND+ P F Y+ + + + V+A D D+G G L + S + S F+++ G I ++L G + V D G P S+ TTV + D E P + + + E+ I V+ + G + L NL D+ ++ D E + + D G P ++ + V ++D+NDN P FS + E++P T+V + A+DKD G+N Q+ Y I D N F + N G + LDR + + + V +D G P +++ I++ D N+ P F Q F V ED + P++ ++ D D+G NA +T ++ D F I G + L+RE++ Y + + A D TV+ V I ++D+NDN+P F + FP P++ L+A + D D GAN V ++ F + RD + R L+ G + +V DRGRPP SS + I I
Sbjct: 85 ASLDREGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSSAPAGTAV-FAVTARDADAGPNGDLRF----SLSGSASAGFSVDPRRGVIHAARALQ---GPRDDLTLTVRVSDGGAPPRSAVTTVTVRFRDAG-EFPRFAPGP--RSFSFREDQPPGTTITVVAARSSRR----------AGPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDINDNAPEFSSSRFWAKVPENTPPRTIVV-LTAVDKDSGINGQVDYSIIDGNIGNV----FRVNPNSGEIRSVSTLDR-ENVASYELTVKATDRGSPTQHCTVKVLISVTDENDNSPRFTQ-IFSAHVREDAAVGFPVL-------RVSTLDADEGPNAAITFSLLDPSLPFSIHPSTGEITVSRRLNREDRSGYAVKVRASDPA------WTVSTDVTIVVDDVNDNAPRFGQTAYYIEFPEPSE-------GEALVARVSASDADDGANGQVFFFMR--SQTENFRVGRDSGEIHSVRPLRYRDPAGGGSGANLNKYSFVVTAMDRGRPPLSSDATVTINI 641 HSP 5 Score: 132.109 bits (331), Expect = 2.472e-31 Identity = 156/613 (25.45%), Postives = 267/613 (43.56%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLN----------KSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI-SDPRTTNQMFPPFLI-ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHG--RPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDK--GVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKD----SGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
L L++S+ + + + D G PPL+ I + + N P F+ +SL EN S L V+A D D+G G + Y S+++ D F I+ +G++ L+ LDY++ E Y+ V A D G A + + V I++ DVND P+++ + S + + + + + P V+++ LD +G+ + F++ K +L Q D Y+ K ++ AF Y S+ + V I VN+ P F +F + E +P+G V V A D+D G++ + Y + + R+ F + E G ++V+ LDR + ++ V+ + G R +++ + + + D N+ PPVF+ + +H V E S +V ++ D D G L N + F I +H G++ + LDRE Y LT++A+D G P T T VV+ L D+NDN P KV+ + ++ L D D G L P YFS+ +K R + E + L V D G PP +S++ + +++ D
Sbjct: 707 LHLRASLAGDAGSIFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFAHPPLELSLPENHPAGSSL-ARVTATDTDAGVNGAIVY--SIASGDGSGL-FDISRASGDVLLVGELDYET--EKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLD---DGEADLFVLNQK-TGVLTTQGFLD---YET--KQTYELTVRAFNYPDTF--------HYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKG-----FSVNEHTGEIIVSSQLDREREASA-TLRVIAKNAGSIRGFDVDEVLVNVAITDAND-PPVFSSALYHGRVSEAASVGTHVV-------GVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPA----TGTTVVVVALEDVNDNGPFL---LTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLGSDPAWRG-YFSLS-SSGLLKTARPIDREQKPEFHLPVAIADAGSPPLTSTVTLHLSVLD 1273 HSP 6 Score: 125.176 bits (313), Expect = 4.092e-29 Identity = 134/589 (22.75%), Postives = 246/589 (41.77%), Query Frame = 2
Query: 623 DRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL-FKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQL--TLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVI--FLNDLND----NSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANA-VVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
++ V+ D G PPL+ + +TI I+ N N P F +Y + + + + +++SAVD D G+++Y N R F +++ G + L SL D+G+ +S V A D G+P LSS T II++ + N P + ++++ EN+ + V+ D D G+NG + G L + D+++ + D E E ++ D G + T +++ + DVNDN P + I E++P GT V + A+D D N+ +Y + D F++ +L Q + + + V ++ + ++ + + +N P F Q ++F V E P +G + +D D G++ + L + F ++ H G + + LDRE + L +IA + IR V++ + D ND +S ++H +VS V ++ + D DS I+ G FSI+ + + L E ++ L V+ D G PP + + + + ++D
Sbjct: 615 NKYSFVVTAMDRGRPPLSSDATVTINIVVPNANAPRFLRERYSTPVAATVRAGTRI-LDMSAVDPDRDVNGQIAYSVVGGN---ASRRFDVDA-GGFLHLRASLAGDAGS--IFSVTVEARDRGRPPLSSRATAIISVTEENQYAPRFA--HPPLELSLPENHPAGSSLARVTATDTDAGVNGAIVYSIASGDGSGLFDISRASGDVLLVG-----ELDYETEKLYNLSVCAADGGWQAKTECSGVSISVTDVNDNPPMLNASDYYPVIPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADL-----FVLNQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSES-------APVGAPVGSVFATDRDAGIDGTVFYMLFGESRSKGFSVNEHTGEIIVSSQLDREREASATLRVIAKNAG---SIRGFDVDEVLVNVAITDANDPPVFSSALYH------GRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLIVVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALED 1168 HSP 7 Score: 98.2117 bits (243), Expect = 7.019e-21 Identity = 97/385 (25.19%), Postives = 168/385 (43.64%), Query Frame = 2
Query: 1325 GIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDG-EIFSVIVVVSDHG-RPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQIS-HNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGI-IAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESK--EKINKEMIVITIAVIISV 2458
G P LT + +TV++ D NDNLP F ++ E +PIG+ V V A D D GLN+ + Y + R + F + S G ++ LDR +G E + + V D G P LS+ + + + D+N+ P F + + P P + + D D G N L ++ + + F + G++ + L + +++ LT+ DG R VT +V + D + F R P P S++E V + S V + G + F++D V ++R L E+Q ++L+V +D G PP S+ +++++ + D N F+ S+ K+ + TI V+ +V
Sbjct: 2 GEPRLTGTGTVTVLVEDENDNLPRFGAAELRAAVPEDAPIGSDVALVNATDADAGLNAIISYRL---RGGDGHF--SVNPSTGQIITTASLDR--EGRESYVLEVTALDGGPTPGLSSSATLVVAVTDVNDHTPRFLNAPYVAYAPSS-------APAGTAVFAVTARDADAGPNGDLRFSLSGSASAGFSVDPRRGVIHAARAL-QGPRDDLTLTVRVSDG--GAPPRSAVT-TVTVRFRDAGE----FPRFAPGPRSFSFREDQPPGTTITVVAARSSRRAGPVSYHLASGGNLGDVFAVDPQSGEVSVHRALDHEYQHHYELVVEARDSGFPPFSAYLKLEVDVLDIN----DNAPEFSSSRFWAKVPENTPPRTIVVLTAV 360 HSP 8 Score: 88.9669 bits (219), Expect = 3.897e-18 Identity = 120/461 (26.03%), Postives = 192/461 (41.65%), Query Frame = 2
Query: 377 DLNDNAP------HWPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPIN-VSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIIN--IVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNS-----QLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCP 1717
D+NDN P ++P I ENA GT + AVD D + ++ F L + L + +D ET EL + + + +QI VN+ +P F +Y + E+ + + P+ V A D D+G G + Y + +S + F++N GEI + LD + E S + V+A + G V++N I D ND P+ S +L + E ++ +V VS HD D + FLI F N +I + DRE T+ D G P T + ++ V + DVNDN P + +S + E+ P G V + A D D N QL+ SDP F + S+G L + +DR E F + V ++D G P L++ + + ++++D N+ P
Sbjct: 852 DVNDNPPMLNASDYYPV-----IPENAPSGTTVLVMDAVDADSPSNAVTMYSLDDGEADLFVL-------NQKTGVLTTQGFLDYETKQTYELTVRAFNYPDTFHYSTAQVHVQITGVNEYFPRFVQREYNFVVSESAPVGA--PVGSVFATDRDAGIDGTVFY---MLFGESRSKGFSVNEHTGEIIVSSQLDRE--REASATLRVIAKNAGSIRGFDVDEVLVNVAITDANDP-PVFS--SALYHGRVSEAASVGTHVVGVSAHDFDSPPGWRTFSFLIQSGNAGRAFSINAHTGLI---VVASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPF--LLTSSAKVTENQPAGMTVLNLEAGDPDLPPNKGPYTFQLLG--SDPAWRGY----FSLSSSGLLKTARPIDREQKPE-FHLPVAIADAGSPPLTSTVTLHLSVLDQNDNP 1278 HSP 9 Score: 62.003 bits (149), Expect = 7.038e-10 Identity = 62/234 (26.50%), Postives = 106/234 (45.30%), Query Frame = 2
Query: 593 LKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCD-SGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEP-----IVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFD 1276
+ S +DRE+ L ++ D G PP TG ++ + + DVNDN P T ++ EN Q + +N+ A D D N G +++ + +D R + S++G ++ + +D + E + V D G P L+S+ T+ ++++D ND +D+ + N P I DV D D I+ +FNC L F+ N LI A+ +F+
Sbjct: 1130 VASPLDRESVPLYNLTVVAVDMGEPPATGTTVVVVALEDVNDNGPFLLTSSAKVT--EN-QPAGMTVLNLEAGDPDLPPNKGPYTFQ--LLGSDPAWRGYFSLSSSGLLKTARPIDREQKPE--FHLPVAIADAGSPPLTSTVTLHLSVLDQNDN------PSEARDVRV-HVNYFGSPFPGGFIGDVRPRDPD--ISDRFNCDLTSGPFNVFSFQPNTCRLISQPRSAEGRFE 1347
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO46189 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQM0]) HSP 1 Score: 220.32 bits (560), Expect = 1.074e-58 Identity = 184/611 (30.11%), Postives = 294/611 (48.12%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGI---ITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRH------ELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+ + +DRET LV+ T++GS GE + TI++LDVNDN P F+ Y SL EN + + V+A D D G K++Y+ SV +T F +N G + + LD + ++ SYS V A DHG+P+ S+ + + I D+ND P S +K +T+ EN I+ V D D G NG+ +I G+ G + + ++ DRE A TI+ D G+P S+ + + + D NDN P F+ TS+ I E IG+ V V A D+DEG N+Q+ Y I T+ F I + NG L V + ++R +++ + SD G P +++ E+T+ + D+N+ PPVFN ++ +V E+ + ++ +A D D G NA L +I ++ +F+I S +G++ + LD EEK +Y L + A D ++T +V I + +LND +P F T+ +Y VR ++ + D+DS + + SI G + FSID+ + L E ++ + V D G PP S+ + I I D SPK
Sbjct: 1051 ISVAKRLDRETTANYTLVVRATETGSQ---GESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVA-KVTATDRDEGENAKVTYELSVGDT----SKFEVNPATGLVTTKRPLDRE--DQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYT--LTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVV-----DREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTS-----AFAINAMNGVLTVKKEINRET-VPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLT-------VAADDSDVGANAVLRYSIISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEVTATDS------KYTAKTNVTIRVINLNDITPAF-------TQQNYTASVRENSPTSTSVVKVSASDRDSFGS--LSYSIVGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPK 1616 HSP 2 Score: 207.223 bits (526), Expect = 1.435e-54 Identity = 188/624 (30.13%), Postives = 293/624 (46.96%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIA------LFVEDKDSGANAVVDLSIKPGIIAPYFSIDR 2221
D+NDNAP + + + + E+ +G++ AVDLD + + +SYF T D ++ K + DRET ++ + D GSP +G+ + I+ILDVNDN P FS+ +Y S+ E+ + + + + V+A D D+GN L Y + NT+ F +++ G + + +SLD++ SY+ + D G P L+ ++ ++IN+ D+ND P+ S S + EN VS D D NG F I D +F + S II +AK D E + T+ D G+P + +T+ I DVND+ P FS S I E + IG+ V V A D D G +L Y + + + F I++N G++ V+ LDR +S+ V D G + S+ +TI L DIN+ P+F Q + F V E S IG +A +D D N + A+ DN + F I + G++ LD E+K +Y +T+ A DG + TV V + ++D+NDN P F ++ Y V L A + D DSGAN + SI G F++DR
Sbjct: 160 DVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYF------TVDSQGV--IRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAM-VTVTASDKDNGNNADLRYSFTSGNTN---HAFTLDAVTGVVTVSRSLDFE--QRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFS--PSAYQSRVKENTPAG---TQVSATDRDSSTNGAL-VFGIIKGNDDGVFTIDGSTGIIS--IAKSP-DYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL----ISGNVKGAFNIDANSGSIRVSSELDRETTPS-YSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSS-------PGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTV---VKVMVDDVNDNPPQFAKSL-------YTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDR 737 HSP 3 Score: 187.963 bits (476), Expect = 1.810e-48 Identity = 217/760 (28.55%), Postives = 338/760 (44.47%), Query Frame = 2
Query: 206 HVHSYFRL-SSSGIISVARQLDCDNDSNLCDKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKL---KSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI---KDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNF--------PLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT---IDDSQPL----SPKNMVHFNESKE 2407
+ S F++ SSG+ISVA++LD + +N TL T+ + I + D+NDNAP + P S+ EN IG A D D + K +S F++ P L K +DRE L + D G P + IT+ I D+NDN P FS KY +++ EN S + + V A D D+G G+++Y N + F I+ST G I ++ +D ++ SY+ + A D G P S+ V I + D ND PI + N++ I E ++ + V+ D D+G N Q ++ +G F N + + L K + +RE TI D G P +TS + +TV++ DVNDN P F+ + S+ E+S T V V A D D G N+ L Y I + F I S +G ++ LD + + + V +D A +N +TI +I++N+ P F Q + +V E+ P + + VS D+ L+ +I KD+ +KF I +G++ + VLDRE Y + + D G P + VT I + D NDNSP F + P+ S+K L D D G NA + ++ F I + L + L E++ + L + +D G PP++SSI I++T I+D +PL S + V N+ KE
Sbjct: 1037 NAGSSFKIDQSSGLISVAKRLDRETTANY---TLVVRATET-GSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDTSKFEVN----------PATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNI-LRVLASDPDAGANGRVTYSIISGNHGNA---FRIDSTTGRITVVGVVDREA--LASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNET--SYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV--RGDTSAFAINAMNGV---LTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKR----FKINSTSGVIMTTTPLD-FEEKSQYGLEVTATDSKYTAKTN---VTIRVINLNDITPAFTQQNYTASVREN---------SPTSTSVVKVSASDRDSFGSLSYSIVGGKDS-DKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVT----IKILDENDNSPKFDSSSYSSSILENSAPSSFSFK---------LAATDADEGTNARITYNLSRN---DAFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKE 1735 HSP 4 Score: 187.193 bits (474), Expect = 2.924e-48 Identity = 208/807 (25.77%), Postives = 364/807 (45.11%), Query Frame = 2
Query: 179 NSSTRFNMLHVHSYFRL-SSSGIISVARQLDCDNDSNLCDKTLEYCMT---KLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLI-ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLT--LAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSM 2569
N R+ + F + +S+G+I++ QLD + K +Y +T K + + V+ ++++D+NDN P + K + ++ EN G A D D S ++AF + ++ + +DRET L I D + I I D NDN PTF T ++ E+ + + ++A D D G G ++Y N F ++ +G + + +LD ++ SY+ VV A D G P S + ++ ++++DVND P KSL I E+ +++ ++ V V D D+G NG L G +G D N + +++K D E A T+T D G PS +++ + + I++VNDN+P+F PA SI E I T V K+ A D D + L + I + F I +S+G + V + LDR ++++V ++ G S TI ++D+N+ PVFN ++ ++ E+ +P + + + +D D+G NA++T L++ D +KF+++ G++ + LDRE++ Y L + A+D G P + ++ + +NDLNDNSP F ++ T V+ ++ + D D+GAN V SI G F ID + + + E + L + KD G PP S+ + IT+ D SP + NE+ I++ +++GS + +V R + + Y + D A ++
Sbjct: 614 NGDVRYALSDNTDVFSINTSTGLITLKTQLDYE-------KKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDAD---SGANGKISYSILSGNENMAFAM---DRFTGEITTRVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSPTGTRVG-QLTATDRDIGPNGAVTYAIISGNQ---GNSFQLDPRSGILSVRSTLDRET--IPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAP--RFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSLSG-EGSD-----NFTIDSTGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDIVE----GNAGSSFKIDQSSGLISVAKRLDRETTAN-YTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHEN-------LPIGQTVAKVTATDRDEGENAKVTYELSVGD-TSKFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKP----SQSAVAAITLTINDLNDNSPQFSQSKYTLT-VTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSP--IFASNETSYGIDEG------------VSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAI 1357 HSP 5 Score: 182.185 bits (461), Expect = 1.260e-46 Identity = 169/595 (28.40%), Postives = 276/595 (46.39%), Query Frame = 2
Query: 608 DRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLA-IKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFH-RNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
DRE+ R L +L D+ + G ++ I + D NDN P F + Y+ ++REN + V+A D DSG ++Y S + F +NS GEIR + LD+++ + SY+ + A D +I + DVND P +L S+ ++E+ + + ++ DLD GIN + + L+ G + + Q + + K FDRE +A + D G PS + + + I+DVNDN P FS + S+ E IG + V A DKD G N+ L Y + TN F L G + V++ LD +++ + V+D G P L++ + IN+ DIN+ PPVF+ S + V E + P + ++ +D D N L IK N + F I G++ D E K Y LT+ A D G P +++ T V IF+ D+ND+SP+F N+ ++ + ++ + D DSG ++ + G + F+ID + S++++ +L E + L V +D G +SSS + I + D SP
Sbjct: 29 DRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI--VTATDRDSGTNAAITYSLF-----SGENKFMMNSKTGEIRTVTPLDHETKD--SYTMRISAFDGKHTTF----VPLITVDDVNDNAPFFAL--SVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGV-------IRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGN-TNHAFT--LDAVTGVVTVSRSLD-FEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKE----NTPAGTQ------VSATDRDSSTNGALVFGIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVP---VKYD-TAQVTIFIEDVNDHSPVFSPSNY--SKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSP 581 HSP 6 Score: 175.252 bits (443), Expect = 1.958e-44 Identity = 169/569 (29.70%), Postives = 270/569 (47.45%), Query Frame = 2
Query: 377 DLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLREN-FQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK--FQISH-NGMLQSVAVLDREEKEEYKLTL-IAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFH 2065
D NDN+P + I E IG+ + A D D + ++ +S F + + L +K I+RET L I +D GSP +T + +T+ + DVNDN P F++ YI S+REN Q S+L V+A D D G L Y +S D ++ F INST+G I LD++ ++ Y V A D ++ T V I ++++ND P + + ++ EN+ + +V VS D D G + ++G K D S +I DRE + + D G P L++ +T+ I+D NDN P F + S SILE+S + K+ A D DEG N+++ Y++S N F + S+G + + Q LDR + + + + DHG P ++ I I + +IDIN+ P+ N S+ +V E+ PK ++ I SD D G+NA+LT ++ N +K F + + G + + LDRE++ Y L + +A G P + + V+I + D +DN P F
Sbjct: 1300 DENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSAFAINAMN-------GVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVL--TVAADDSDVGANAVLRYSI-ISGND--EKRFKINSTSGVIMTTTPLDFEEKSQ--YGLEVTATDS---KYTAKTNVTIRVINLNDITP--AFTQQNYTASVRENSPTSTSVVKVSASDRDS--FGSLSYSIVGGKDSDKFSIDQRSGII----STADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYNLS----RNDAF--MIGASSGVITLAQPLDR-ENKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQ-------PKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSL----SSVADVIIDVIDEDDNCPRFQ 1825 HSP 7 Score: 152.525 bits (384), Expect = 2.273e-37 Identity = 148/558 (26.52%), Postives = 242/558 (43.37%), Query Frame = 2
Query: 695 IQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLA-IKDNI-NKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
I + DVNDN P F+ Y + E+ + S++ ++AVD D G +LSY +T +F ++S G IR + D ++ + SY + A D G P+ S TV I I+DVND P+ S + ++ E+ + +V V+ D D G N F G+ D + + D E+ + ++ D G P LT + + + + D+NDN P FS A + E++P GT +V A D+D N L++ I F I+ + ++ + + + V D G P + ++TI + D+N+ PVF+ S + +PE +V + +D D G +L I N+ F I N G ++ + LDRE Y L + A D + + V I L D+NDNSPIF P +VS H++ + D D +N V ++ FSI+ + L +L E + + + V KD G P +SS +++ +DD
Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVR-QLTAVDLDVGINARLSYSLVSGDT----SYFTVDS-QGVIRTKGAFDRET--KASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFS--SAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTL-----DAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QVSATDRDSSTNGALVFGI----IKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVT-------VTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARD---GGSTSRSSSTRVTIALQDINDNSPIFQG--PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDN--TDVFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDD 677 HSP 8 Score: 117.857 bits (294), Expect = 9.441e-27 Identity = 87/293 (29.69%), Postives = 146/293 (49.83%), Query Frame = 2
Query: 605 IDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKD 1483
+DRE + + +TD+G+PPL+ +TI+ILD NDN P F + Y S+ EN +S ++A D D G +++Y S ++ F I +++G I L + LD + N+ +Y + A DHG P +SS T+ + ++D+ND P+I N S ++ EN ++ + D D G+N + L+ ++ + N + + K DRE++A I D G PSL+S + + ++D +DN P F + +I E P G + +V A D D
Sbjct: 1575 LDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSF-SFKLAATDADEGTNARITYNLSRNDA------FMIGASSGVITLAQPLDRE--NKSTYDLAIQARDHGTPPQASSITIRVTVIDINDHRPLI--NSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVFTLDNTTG----DISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852 HSP 9 Score: 96.6709 bits (239), Expect = 3.487e-20 Identity = 96/378 (25.40%), Postives = 160/378 (42.33%), Query Frame = 2
Query: 1265 HKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEIT------------INLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLA-IKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDG-TPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
KFDRE E+ T+ D ++ + + D NDN P F + + F+I E++P V V A D+D G N+ + Y L ++N GEI +V + DH S + I+ I + D+N+ P F S + V ED V + + D D G+NA+L+ + + + + F + G++++ DRE K Y++ L A DG +P + TV I + D+NDN P+F + V + ++ + DKD+G NA + S G F++D V ++R L E + + L + DRG PP + + + I ++D
Sbjct: 26 RKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDVKDENDNAPEFPLNSYVFNIRENTPAAQVAI-VTATDRDSGTNAAITYS--------------LFSGENKFMMNSKT-----GEIRTVTPL--DH-ETKDSYTMRISAFDGKHTTFVPLITVDDVNDNAPFFALSVYKTGVYED-------VAVGSIVRQLTAVDLDVGINARLSYSLVSGDTSYFTVDSQGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVE----IEILDVNDNRPVFS-SAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVND 368
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO35412 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLK9]) HSP 1 Score: 202.986 bits (515), Expect = 2.946e-53 Identity = 180/615 (29.27%), Postives = 295/615 (47.97%), Query Frame = 2
Query: 596 KSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH--FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL--------NKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQF----------NCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQH-LDRLLDGEIFSVIVVVS--DHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN---INK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYV-RHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI 2350
K +DRET D +L I TD G+P L G +I I ILD ND+ P F+ + Y+ S+ EN + + + VSA D DSG+ G + Y + D+++ + F ++S+ G IR ++LD++ N SY+F V+A D G P+ + TV IN++D ND P + + +K+++ EN+ +N I + V D D N Q CF + GF Y + + DRE F T+ D G+PS ++ + + + DVNDN P F+ A + +I E + G+ V ++ A D DEG N + Y I T F ++ L+ LDR ++ SV + ++ DHG + +T+ +ID N+ P F +S++ T+ E S ++ ++ +D D G N ++T I + +N F++ + G+L + + LDRE K Y T++A D G P Q+ +V V + ++D+NDN+P+F +P+ S E +L+ + D D G NAV+ I G FSID + L E + LI+ KD G + + + +T+
Sbjct: 161 KKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSI-LRVSAADRDSGSNGDIKY---AIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKN--SYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRS----ENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGF-------------YFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSI----TGGNDLGWFQVDFQSGLVTTAKPLDRE---QVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQ-------VSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDP--QLMSSV--KVELTISDINDNAPVF---YPVEYFASIMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTV 731 HSP 2 Score: 151.369 bits (381), Expect = 4.770e-37 Identity = 158/609 (25.94%), Postives = 271/609 (44.50%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDL--IIYQLMAKHKFDRE-KEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLP----TFSMPATSFSIL--EHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVV--DLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+ + IDRET +I L + + + P++ + +Q+ D+NDN P F T Y + +RE+ +N+ PIN +A D D+GN G + Y S NT + T + +I D Y + A D G PAL + I I+D ND P+ + N L +I EN I+ VS D D G NG + +D + ++ DL + K D E K ++ + I D G+PS +T+ ++D NDN P T+ P + E+S I T + + DKD NSQ I T F +E G + L + LD E+ +++ + V+D G P+ S + I++ D+N+ P F + + + E L + + +D D+G N ++ +I +++ FQ+ +G++ + LDRE+ +T+ A D G+ TVT +++ D NDN P F ++ +S + ++ + D DSG N + ++S + F ++ + +L E + ++ V+ KD G P SS+++++TI D
Sbjct: 51 ISTTARIDRETTTQISLQLRTLNPSNQPIS----VQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPIN-TATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLG--SIAENTKPGVSILRVSAADRDSGSNGDIKYAI----DWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVI-ASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKI----TNGDDEGCFKVEFLGFYFI--QLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISE-------LAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTII----DGNDNKPRFMKS-SYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISD 629 HSP 3 Score: 150.599 bits (379), Expect = 7.917e-37 Identity = 179/698 (25.64%), Postives = 297/698 (42.55%), Query Frame = 2
Query: 377 DLNDNAPHWPKPIELSISENAFIGTLF-NIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPT----DDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFST-----HKYIISLRENFQLNSLLPINVSAV---DCDSGNFGKLSYKHSVSNTDS--------VKRHFAINSTNGEIRLIKSLDYDSGNELS--YSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRT-TNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF---HRNFPLPTKVSYKEYVRHELIA-LFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
D ND+AP + ++N+++G++ N P V + R + + D + + D + ++ K ++D E + ++ +D G P +TI +LD NDN P H ++R NSL+ N++ + D DS + K ++N D + +F I+L K LD EL Y+ + D G P+ S+ V+I++ DVND P + N +I+ N ++ ++ D D+G NG + + G G DL + Q D + DRE+ + TIT D+G T S +TV I+D NDN P F + +I E + IG V +V A D D G N ++ Y IS N +F L G L LDR ++S V+ DHG P L + +++ + + DIN+ PVF + ++ E+ P + + +D D+G NA ++ I +N F I S G++ ++A LD E +E + L + A DG + V V LN DN P+F NF + Y+ + L+ ++ KD N + +I G F +D +K+N + E + + L VI + P S+ + I + D +P+
Sbjct: 198 DENDHAPVF--------TQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSE---NSLINTNIAYILVTDKDSNTNSQTELK--ITNGDDEGCFKVEFLGFYF--------IQLQKPLD----RELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNG--SYVLQLNATDPDEGDNGTVSYSITG--GNDLGWFQ--VDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFE--LNTQTGVLWTKSQLDRETK-SLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMEN--------EPPGKLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVN--VTVLNKA-DNLPVFLYEMYNFTV-----YENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQ 843 HSP 4 Score: 146.747 bits (369), Expect = 1.255e-35 Identity = 151/610 (24.75%), Postives = 275/610 (45.08%), Query Frame = 2
Query: 578 FP--KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVS-AVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDS--GNELSYSFVVVAHDHGQPALSSSTT-------VIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGM---LQSVAVLDREE----KEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQI 2344
FP KL ++ S+ + +L++ TD G P + +TI I D ND+ F + + ++ EN +L+ V+ A+D K V + S + HFA++ +G+I LD + N S +++ A A+ + TT VI+ + D+ND P+ S +++ IT+ E + P+ + D D+G N +F L+ G D F + + +L DRE + + D +L S+ I + + D ND P F + +I E + IG++V + A DKD G N + Y IS+ + F +ES G L+V + LD +++ + + DHG LS+ + +T+N++D+N+ P+F TV E+ + P +G SD D G NA + ++ S N + ++A +D E ++ ++L ++A D G+P + R ++T + + D NDNSP F P + + ++ + ED D +N V SI G YF++ +++ ++ ++ I++L + D G+P + + + +
Sbjct: 997 FPGGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHS-------RTKDIVYSLISSESHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAE-----AMYNDTTIKRDKAIVIVTVTDLNDNAPVFS--RAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKFFINSSTG----ELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN----GNLAAMFDVESATGRLIVAKSLD-FETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFP-------VGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSIT----VQVTDENDNSP----GFVSPPAAAAGSSLN--VMTITAEDPDRNSNGKVTYSIISGNNG-YFNLHPSTGQLQMIHQIP-DNPTIYQLTIQASDGGQPSRQTQTVVSV 1564 HSP 5 Score: 127.102 bits (318), Expect = 1.321e-29 Identity = 144/515 (27.96%), Postives = 222/515 (43.11%), Query Frame = 2
Query: 881 RHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPII-SLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQ---LMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS-DPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHL----PLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQISHNG--MLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNM 2383
+ F NS G I +D ++ ++S + + QP +V + + D+ND P +L +L+ I E+ ++N + D D G NG + + I F + ++ K DRE F IT D G P+L LI + I+D ND+ P F+ + SI E++ G + +V A D+D G N + Y I D +N +F L S G + Q+LD + ++ V+ SD G P+ ++ +TIN++D N+ P Q + P + + L+ NI YI V+D D N+Q L I D+ F++ G +Q LDRE Y LTL D G P R T+ G V+I + D+NDNSP F N +S ++ L D D G N V SI G +F +D V + L E + + +D G PK+ S + +TI D P+ M
Sbjct: 40 KQFGFNSNTGVISTTARIDRETTTQISLQLRTL-NPSNQP-----ISVQVQVDDINDNEPRFPTLYYTLR---IRESMDVNTTNPINTATDPDAGNNGTVD-YTIASGDNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFD--LDSSTGVIRTKQNLDFEVKNS-YTFNVIASDGGVPSKNDLATVTINVLDTNDNSP---QLKITYLPPHNGDKAIRSENSLINT--NIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKGVPS---RSTL-GFVLIDVTDVNDNSPAFTSN-AYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFM 531 HSP 6 Score: 121.324 bits (303), Expect = 7.792e-28 Identity = 152/571 (26.62%), Postives = 239/571 (41.86%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGE--IFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK--FQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRN 2071
D NDN P + K + +ISE A IG A D+D + + L L T Q L KS +DRET +L D G P L + + I D+NDN P F +Y S+ EN LL V+A D D G +SY N + +F+I+S+ G I + SLD++ E +S ++ A D G + + V + +++ D LP+ + + T++EN + V D+ NG + ++ +L + +I DRE++A + + L++ + + ++D NDN P FS + I +G VV A+D D G N + Y + T+N ++ ++G + + + +L DG+ ++V V+ SD G P + + I I L IN+ PP F S++ V L P Y+ D D G N QL +I + F I G L L + K Y L + A D G P VT I++ D ND+ +F N
Sbjct: 522 DGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSDAQVNGLFELNT----QTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL--QVTATDADEGTNAVISYDIIGGNNNG---NFSIDSSTGVISTLASLDHEV--EEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLY--EMYNFTVYENVPKGTLVGRVYATTKDK--NGSISYAIVSGDPTNLFLVDSTGGII----KINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQL----TSNAEGLLWINSTSGVIKLAR---KLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SINH-PPKFTLSSYVTHV-------LASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPGGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVT----IYIQDSNDHRSLFVNN 1053 HSP 7 Score: 119.783 bits (299), Expect = 2.705e-27 Identity = 173/689 (25.11%), Postives = 290/689 (42.09%), Query Frame = 2
Query: 377 DLNDNAPHWP-KPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREK-----EAFAYTTITCCDYGIPSLTSSQLITVIIV-DVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAV----SDCDKGVNAQLTLAIKDN--INKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE--LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSV----KLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
D NDNAP + + + I +G + AVDLD K L + KL K + ET ++ +L +DSGSPP +TI I ++ P F+ Y+ + + L S V AVD DSG G+L Y N + + F G++ + KSL + SY +V A D G P+ S+S V I I D ND + +N + + + EN++ + + H LD LI + + D+ Q+ + + DRE+ + Y Y ++ + I ++ V D+NDN P FS + ++ E S G+ V +++A+D DEG N++ Y + ++ F+ S G L HL + LD E ++++V +D L + +I I + D N+ PVF +S + + ED IG + + SD D G N + +I + F + S G L LD E + Y+LT+ A D I + T +V + + D+NDN+P+F P ++ +E V + D+D+G NA + S+ + FS++ + ++ + + +L+V+ D+G P S+ I + + D SP
Sbjct: 836 DRNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTSNAE-----GLLWINSTSGVIKLARKLTDGDETQYTVQ--VLASDSGSPPQ--HSTMTIHITLSINHPPKFTLSSYVTHVLASQPL-SYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFP----GGKLYIRKSLL--QALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLF-VNNTFR-FAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAV------DVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMDKF---FINSSTGEL----HLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDAL-----------IGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQD---HGLIPLSSTVNVTVNVLDVNDNAPLFPTQ---PVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSP 1476 HSP 8 Score: 114.775 bits (286), Expect = 8.377e-26 Identity = 133/505 (26.34%), Postives = 229/505 (45.35%), Query Frame = 2
Query: 218 YFRLSSSGIISVARQLDCDNDS--NLCDKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPIN-VSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDS--GNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSD-HGRPALSNQIEITINLIDIN 1708
+F SS+G + +++ LD + S NL K + L+ I D ND P +P+ ++I+E+A IG+L ++L+ + K+ IK S +LA + D E +L + S+D ET EL I D G PL+ +T+ +LDVNDN P F T +++REN +N+ P+ +A D D+G +++ S T S + F++NS EI I ++D ++ S+ VV+A D G P LS+ ++ + + D ND P + ++LN ++ ++ D D+ NG+ +I G+ G+ L +I+Q+ + TI D G PS + +++V PTFS S+ E+ GT V V A LN + Y+++ + +++S G + + +DR G F+++V D G A ++ +TI + D+N
Sbjct: 1207 FFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVG------DSNDQRPVFPESDYTVNITEDALIGSL-----VINLNASDKDIGQNGLIKYSISNGNLAAM-FDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVREN--VNTGFPVGRCTASDRDTGTNAHIAFSM-YSQTPS--KTFSVNSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGF-----VSPPAAAAGSSLN--VMTITAEDPDRNSNGKVTYSIISGNNGYFNLHPSTGQLQMIHQI-------PDNPTIYQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIEYYLTSDSSKGGF---EVVKSTGVVKTTRGIDREGMGASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO40470 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S751]) HSP 1 Score: 195.282 bits (495), Expect = 1.141e-50 Identity = 196/686 (28.57%), Postives = 300/686 (43.73%), Query Frame = 2
Query: 602 SIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQP-ALSSSTTVIINIVDVNDELPIISLNKSLKD-ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVR--HELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRG-------------------RPPKSSSIEIQITIDD-SQPLSPKNMVHFNESKEKINKEMIV-ITIAVIISVLALGSFITIVI---------------IKCRKKAKPPLICY 2533
+DRE D L I +D G+P G ++I + D NDN P FS Y ++ EN + + + + VSA D D G ++ Y S+ + F I+ T G I LDY++ + SY VV A D G LSSS V I ++DVND P+I ++ +L + EN + + VSV D D G NG+ N L G G+ + L+D I + DRE + C D G P T+ + + + DVND P F + E++ + T+V V A+D+D G NS+L+Y I++ + F I+ S+G + LDR ++ + V+V D G P LS+ + +NL D N+ P FNQS+++ ++ E+ P+V + D D G N+ + +I N F G++ + LD E + Y + A DG + +V + L DLNDN P+F P V Y E R + L D+DS A+ I+ G FS+D + L + L E Q + L V D G PP S E TI + SQ LS VH + N E++ I+ +++ + S T+ + ++ + K PPL Y
Sbjct: 129 GVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTSI-LQVSASDKDIGTNAEIQY--SIETHSDPQAIFGIHPTTGVIVNNVRLDYEA--KRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESI--IAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVV-LTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVV-------QLLAQDPDIGENSLILYSILTPNTPFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG-----GRSCNATVHVSLTDLNDNQPVFD---PSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSVD-GSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGY 790 HSP 2 Score: 191.045 bits (484), Expect = 2.116e-49 Identity = 178/606 (29.37%), Postives = 283/606 (46.70%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNEL-SYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGE-IFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI-----DDSQPLSPKN 2380
L L+S +D E + L + D G+PPL G +TI ++D+NDN P F++ ++ L E+ + VS D DSG G++S+ +SN ++ F ++S G + L K +DY GN SY+ V A D G P SS+ + + +VDVND P+ N S + E + I++V D+D G NG+ + +N + I K K DRE + D+G P +SS + VI+ DVNDN P F + +F + E+ P+ T + V A D DEG N + Y R Q+ + + G + +Q LDR +FS +V +D G ++ ++T+ + D+N+C P F+++ + TV ED LP+ + IA D +G N+ +T I F ++ G+L V+ LDRE + L ++A D + Q T+T + I + D+NDN P+F T V K + + A+ D D G N V I G F I+ + R L E + L V D G+ + +S ++ +TI +D++P KN
Sbjct: 759 LYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTF-YTVSVFDADSGVLGRVSFSL-LSNPGTL---FNLDSNTGALSLTKLIDY--GNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFG-NWSYT-AHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGLRNGGKIFI-----KSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTY-----RFDTQVAQFIVDKQTGKITTSQVLDREAKASYVFS--IVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNED----LPVGSSLLTL--IATDDDQQGPNSDITYMIVAGPKAFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGN-QSLETIT-YIEINVLDVNDNYPVFINETTFKT-VPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQL-VTIYVEDANDNRPTFDKN 1333 HSP 3 Score: 182.185 bits (461), Expect = 1.333e-46 Identity = 185/679 (27.25%), Postives = 303/679 (44.62%), Query Frame = 2
Query: 377 DLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLD-REEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
D+ND AP + + E + ENA + TL I AVD D ++ + S L + D + + +DRE ++ L +L+ D GSPPL+ + + + D NDN P F+ Y SL EN S + + + A D D G + Y NT F ++ G + ++LD++ + SY+F V A D G S + TV +++ D+ND P+ + S + FEN + + I + D D F+I D +F + S LI + DRE + T+ D G + ++ + ++DVND P FS +F+I EHS +V+ V A+ +D+G N++++Y IS T N + LI S G L + +D ++ + V D G P L +TI +IDIN+ P FN S+ +PED P ++V D D GV +++ ++ N F + S+ G L ++D Y L + A DG + + T + + + D+ND SP+F N+ V +I + D DSG N + + + F + R+ + + KL E + L VI D G P +SSS ++++ +DD +P HF ++
Sbjct: 381 DVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGM--ITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPV-VQLLAQDPDIGENSLILYSILTPNT-----PFFLDPRKGLVTNSRTLDHEV--QSSYTFQVAATDGG--GRSCNATVHVSLTDLNDNQPV--FDPSSYSVEYFENTRIGQSICQLKAIDRDSP-KFAITRFIIEQGNADEVFSVDGSGLITLAKL----LDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIV----LINSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPED-------TPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPR---SSTAMLELKVVDVNDYSPVFG-NWSYTAHVLETTPPDSNIIEVVATDVDSGENGRISYAFDSKVDTSKFGL-RNGGKIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNP----HFQQA 1019 HSP 4 Score: 181.8 bits (460), Expect = 1.839e-46 Identity = 190/680 (27.94%), Postives = 325/680 (47.79%), Query Frame = 2
Query: 377 DLNDNAP----HWPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH---FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQ-FNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNI-NKFQISHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSI--KPGIIAPYFSIDRDRQSVKLNRKLKSEHQG-IHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
D+NDN P + ++ENA IGT D D + KN ++ ++ YF + F +DE + + S+DRET+D L + D G PP T E I + DVND P F H Y + EN +N+L+ I V+AVD D G+ +L Y +++NT + + FAI+ ++G I LD + ++ V+ HD G P LS + +VI+N+ D ND P N+S + ++FEN+ P+V + D D G N L + F L ++ L + D E ++ + D G S ++ + V + D+NDN P F + S E++ IG + +++A+D+D + I + +++F ++ +G + + + LDR + V G+ +++ I + I ++D+N+ PP+F+++ ++FT+ E S L + IG++ DKG NA++ +I K N N I+ G L + +D E+ LT+ A D GTP + VT +V+ D+NDNSP F+ + L ++ + H + V D DSG V S+ PG + F++D + ++ L + + + + L V +D G PP+SS+ +++ + D SP
Sbjct: 271 DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDAD-SGKNGEVNVTLEGGDGYFSMKFDVLNDES---IIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAI-VNAVDQDFGSNSELVY--TIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQV--VLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPY--FNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNTPFFLDPRKGL-------VTNSRTLDHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDS-PKFAITRFIIEQGNADEVFS---VDGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAI-VNITVLDVNDEPPIFSKAEYNFTIQEH-SQALSV------IGHVHAISRDKGTNAEVVYSISKGNTDNIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVI----DINDNSPQFNSSSIL-VRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLSNPGTL---FNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSP 910 HSP 5 Score: 158.303 bits (399), Expect = 3.755e-39 Identity = 168/600 (28.00%), Postives = 269/600 (44.83%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVD-VSVHDLDQGINGQFNCFLI-GHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGI-PSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLD-----RLLDGEI---FSVIVVVSDHGRPALSNQIE-ITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK--FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIF-HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAP---YFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSS 2326
K+ +KS +DRE + L ++ D G+P + + + + DVNDN P F Y ++EN + + L VSA D D G+ G ++Y+ D+ F ++ G+I + LD ++ + SY F +VA D G T V + + DVND P S NK +T+ E+ + ++ ++ D QG N ++ G K F L + + L DRE + D G SL + I + ++DVNDN P F T ++ E PIG+VV V A+D D+G N ++ Y I + T +G +N+ R LD E+ + + V +D G+ + +TI + D N+ P F+++ + E+ VP N+ I D D G+N+++ I + F+I S G++Q+ +DREE EY L + A D Q R T ++ I + DLNDN+P F RN T V E ++ ++ D D+G V+ I++P FS+D +KL L E + L + D G PP +S
Sbjct: 967 KIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGA-VSASDSDEGSNGHVTYRF-----DTQVAQFIVDKQTGKITTSQVLDREA--KASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNK--YSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKAFSL-------NQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNT------------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYEN-------VPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNL---TYVMEDEPFNFQVTSITALDPDTGQGGNVEYR----IVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTS 1523 HSP 6 Score: 156.377 bits (394), Expect = 1.659e-38 Identity = 175/603 (29.02%), Postives = 273/603 (45.27%), Query Frame = 2
Query: 602 SIDRETNDRIELVILLTDSGSPPL-TGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHG---QPALSSSTTVIINIVDVNDELP-IISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG--HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLV-NQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
++D E +R L + TD G T ++TI + D NDN PTF + I + EN +N+ + + A D DSG ++ Y ++ S + HF INS G I+ +D + +E YS V A D Q L ++ T+ I I D+ND P +S N + + E+ N + ++ D D G G ++ F L K + LI D E I+ D G P LTS QL V++VDVNDN P F+ ++ E+ P GT V KV A D+D G N++L Y I ++ F I+ + L+V N LDR F + V + P + + IN++D N+ PP F VPE+ L I + V D D G N ++ +I + F I + G L + LDRE K Y+L++ A D TP +T ++ IF+ D NDN P+F ++ + +S ++ L DKDSG+N + ++ Y SID V + ++ + + I KD+G+ PK + + ++I I+D +P+
Sbjct: 1286 ALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNV-TTIKAHDDDSGLNSRIWY---TIDSQSPRAHFKINSETGLIQTTHPIDREEISE--YSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTY----VMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLI-------GSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDK----FSIDKHSGLIVTNSILDREKKDTYF-LTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARL--------IYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPY---YTAFANITIFIEDQNDNPPVFQQSL-YSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVY-SIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQ 1853 HSP 7 Score: 154.066 bits (388), Expect = 7.907e-38 Identity = 165/628 (26.27%), Postives = 270/628 (42.99%), Query Frame = 2
Query: 602 SIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENF-QLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLL------------------FKQNLSDLIIYQL-------MAKHKFD-REKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLN-SQLIYHISDPRTTNQMFPPFLI-ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK--DNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEY--VRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHK--LIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
++D E+ L ++ T G L G I+ I ++D NDN P F + L E+ + V+A D DSG GK++Y N V F I+ST GEI K LD ++ S+ V+ D G P S++ V + + D+ND P+ L ++ I E+ + V D D+ +N G +L F SD I Y++ A+ D R +++F + D G+P + + +II P F +P+ + E++ +GT V VR D GL ++ Y+I + F I + +G + VN+ LD V+ + D P+ ++ + IN+ D+N+ PVF QS + E +P + ++ +D D G N ++ AI+ D+ F I G++++ LD E + + +++ A D G+P + HT SV I + DLNDN P+F P P V E + L + D+DSGANA + ++ G F ID+ + N E+ +++ L + D G PP SS+I I + + D P
Sbjct: 2024 ALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGV---FTIDSTTGEITTAKLLDRET--TASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLF---DPLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRIIIT----REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNY-------FRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTA-PSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEG-------IPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPM---HTDV-SVTIRVLDLNDNPPVFR--VPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDP 2618 HSP 8 Score: 152.14 bits (383), Expect = 2.813e-37 Identity = 185/684 (27.05%), Postives = 290/684 (42.40%), Query Frame = 2
Query: 377 DLNDNAPHWPKP-IELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFV--VVAHDH-GQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSL-TSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHI--SDPRTTNQMFPPFLIESNGNLLVNQH-LDRLLDGEIFSVIVVVSDHG---RPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI-KDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNS---PIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
D+NDN PH+ + + EN + T A D D FD + Q K+ +DRE I+ TD GS P + +T+ + DVND P FS +KY +++ E+ + S L ++ D G ++Y + F++N G + L+ LD E+++ + VVA D G +L + T + IN++DVND P+ + K T+ E + + V D DQG NG+ + I + D FK N + +I L A D E ++ D G TS QL+T+ + D NDN PTF I E+ PI T VT ++A D D GLNS++ Y I PR F I S L+ H +DR E +S+ V +D + L N + I + D+N+ P F + + ++P + + I D D G + I + KF + G+L+ + LD E+ +Y L + A D G+P + S +F + D + P F R+ + T VS + ++ + D+DSG+NA + SI G+ FSID+ + N L E + + L V P + SS ++I + D PK
Sbjct: 1008 DVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNGHVTYR--------FDTQVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSSPRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMIVAG-----PKAFSLNQVTGVLTLVSPLD----REVTHRHILHVVASDKGGNQSLETITYIEINVLDVNDNYPVFINETTFK--TVPEKLPIGSVVAAVLAVDSDQGDNGKVR-YKIVNGNTDGTFKINETTGVISTLRA---LDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH------FKINSETGLIQTTHPIDREEISE-YSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTYVMEDEPFNF--------QVTSITALDPDTGQGGNVEYRIVSPDTGKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLT-------SYQLFNVVVVDVNDNPPEFTRDLFIGT-VSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPK 1645 HSP 9 Score: 137.887 bits (346), Expect = 7.456e-33 Identity = 209/836 (25.00%), Postives = 339/836 (40.55%), Query Frame = 2
Query: 110 SVEERFPVNYFVTDLKNILAIPL----NSSTRFNMLHVHS--YFRLS-SSGIISVARQLDCDNDSNLCDKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSS---------IDRETNDRIELVILLTDSG---SPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRE---NFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK-DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYV-----RHELIALFVE---DKDSGANAVVDLSIKPGI-IAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAK 2515
+V E+ P+ V +LA+ N R+ +++ ++ F+++ ++G+IS R LD + + L T + +++ I + D NDN P + K PI I EN I T A D D S + D + K+ S IDRE L + TD L + I I D+NDN P F + + + NFQ+ S ++A+D D+G G + Y+ + + D+ K F+++ G ++LI SLDY+ + Y+ + A D G P L+S + +VDVND P + L T+ EN +V V+ +D D G N + + D S LI+ + DREK+ + T+ P SS + + ++D NDN P F P + + E+SP + T + D D G N++++Y I T + S G L LDR + + V D P + ITI + D N+ PPVF QS + T+ E L P +I + SD D G N + + D + I S G++ S A + K+EY IA D D ++ V I + D N+++P F TK Y+ ++ L+ + D D N V + F ++ + SV+ + + QG H L +I +D G PP +QI I + Q P+ N++ +++ I +GS+IT V + A+
Sbjct: 1232 TVPEKLPIGSVVA---AVLAVDSDQGDNGKVRYKIVNGNTDGTFKINETTGVISTLRALDFEVTNRYV---LRVSATDMGKKQQKTSYQLVTIYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDD---------------SGLNSRIWYTIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFVSRNLTYVMEDEPFNFQVTS-----ITALDPDTGQGGNVEYR--IVSPDTGK--FSLDLKTGVLKLIGSLDYE--DVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPP--EFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHSGLIVTNSI----LDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLIYT-LTVQDLDYGNNTKVLYSIMSGNTDGAFT---IGRSTGELSTTTKLDRETKAS-YQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISE-------LTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIV---PVRIKIEDKNNHAPQF-------TKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPR---FLNQTPARVS----------IPENSKVGSYITTVRARASSDAQ 1994 HSP 10 Score: 131.724 bits (330), Expect = 5.485e-31 Identity = 171/699 (24.46%), Postives = 282/699 (40.34%), Query Frame = 2
Query: 377 DLNDNAPHWPK-PIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHK-YIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKS--LDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEP--IVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVT----------------------------KVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAIDGT-PDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVE--DKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
D N++AP + K P E+ I N L + A D D K S F+ E ++ + R L I+ D GSPPL G GI+ I I ++ D+ P F +S+ EN ++ S ++ V + + +++Y N R F ++ G I + + LDY+S ++ +VA G +L+ + IN++D ND P + L + E+ +P +V V+ D+D G NG+ G++ ++ +L+ DRE A I D GIP +++ + V++ D+NDN P F P + +I E + G VVT +V A D+D G N+Q+ Y P T + + G + + +D + + V D G P + + I I P F ++ VPE+ ++ + V+D G+ +N N F+I +G++ LD E K + L + AID T P +R V I ++D+ND P+F ++ + + E + I + V DKDSGAN V +I+ G F+IDR ++ R L E H + V D G PP + + + I + D
Sbjct: 1846 DKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVV---ESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSY----ITTVRARASSDAQVTYSIISGNK---GRAFYVDPFTGVISVASADALDYESTK--NFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLA--EDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLL-----DRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSF--PITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRI----IITREPKFELPSYFGKVPENAMMGTSVLT-------VRVTDNAAGLPLGRISYNIENSNYFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRV----PVYINVSDVNDEKPVFGQSGYM---AQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLD 2504 HSP 11 Score: 130.954 bits (328), Expect = 9.625e-31 Identity = 160/639 (25.04%), Postives = 269/639 (42.10%), Query Frame = 2
Query: 599 SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDK--DEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVF-NQSTFHFTVPEDPSDHLPLVPKPRNIG-YIAVSDCDKGVNAQLTLAI--KDNINKFQISHNGMLQSVA---VLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLN--DLNDNSPIFH-RNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITI---DDSQPL-SPKNMVHFNESKEKINKEMIVITIAVIISVLA 2464
S +DRE D L + T P + I ++D NDN P F + + + EN + + V D D GN K+ Y NTD F I + GE+ LD ++ + SY V A D P ++ + I I D ND P+ +SL TI E I++++ D D G NG + + + + + + + ++ + +E F D G + + + I D N++ P F+ I ++ +VT V A D D+ N ++ Y + D + + + F++ESN G++ + G ++ ++ DHG P L + I + +I + PP F NQ+ ++PE+ +G YI +AQ+T +I + F + + SVA LD E + ++L L+A TP + ++ G +++ +N D NDNSP FH N + ++ + D DSG N V SI G A F+ID + + L E L++ G D G PPKS++ ++++ + +D+ PL P + V+ E T AV+ SV+A
Sbjct: 1602 SILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENSPARLIYTLTVQ--DLDYGNNTKVLYSIMSGNTDGA---FTIGRSTGELSTTTKLDRET--KASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPV--FQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNI-VYTLSNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFC----IAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSL---FVVESNTGSVRTSAGFSNPPQGR-HALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPEN-----------SKVGSYITTVRARASSDAQVTYSIISGNKGRAFYVDPFTGVISVASADALDYESTKNFRLHLVA---TPQGWV--SLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIREDTR---------TGAVVTSVVA 2197 HSP 12 Score: 125.946 bits (315), Expect = 3.779e-29 Identity = 161/634 (25.39%), Postives = 281/634 (44.32%), Query Frame = 2
Query: 554 LPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTF---STHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRL-----IKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIP-SLTSSQLITVIIVDVNDNLPTFSMPAT---SFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLL-VNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISH-------NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE------LIALFVEDKDSGANAVVDLSI-KPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQIT-IDDSQPL 2368
+P D E+ + K+ +DRE L I+ + +PP + ++ +Q D+NDN P+F ++ K ++ F+ + + AVD D G+ SY N +V + + T+G++ S+ D SY + A D G PA + I + D ND P S N S TI EN ++ I+ VS D D G N + + H +F + + +I + + D E + + D G L+SS ++ + ++DVNDN P + T S+ + E++ IGT V +V D D G N ++ + M F + ++ +++ V Q LDR F V + D G P + + IN+ D+N+C P F++ T+ V E+ + + + + D D G N++L I + H +GM+ + LDRE+ + LT++ D G+P + + SV++ L D NDN P F+++ SY + ++ L +D D G N+++ SI P P+F +D + V +R L E Q + V D G ++++ + +T ++D+QP+
Sbjct: 3 IPADLEYNAGVITTKTVLDREKVSAYNLTIV--EFSTPPKSYTVLVYVQ--DLNDNSPSFVRGTSAKLVV-----FENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFS-NVSYSG-TIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNV---RLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSM--KFDVLNDESIIAVGQSLDRETHDHFFLKAVCI-DKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTL-------VAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPL----SDNCSVIVNLTDSNDNDPYFNQS-------SYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPN--TPFF-LDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPV 598 HSP 13 Score: 117.087 bits (292), Expect = 1.894e-26 Identity = 90/315 (28.57%), Postives = 154/315 (48.89%), Query Frame = 2
Query: 605 IDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEA-FAYT-TITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQM 1543
+D ET R LV+ D +P + I + DVND P F Y+ E + +++ +NVSA D DSG G++ + ++ + D K FAI+ G IR ++LD+++ ++ V A D G P + + +V I ++D+ND P+ + D+ + EN LN + +++ D D G N + + +IG G L S + + FD E A + Y+ TI D G P L+S+ I V + D ++ P+F+ F + ++ IG V +V A D+D G ++ + +P T+N +
Sbjct: 2365 LDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWSEGIPVGTIV-VNVSAADKDSGANGRVWF--AIQSGDD-KGSFAIDRKTGVIRTQRALDHETIK--THHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRV-PGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLTTNIT----FDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGRVFFVFYNP-TSNAL 2667 HSP 14 Score: 112.079 bits (279), Expect = 5.857e-25 Identity = 168/663 (25.34%), Postives = 282/663 (42.53%), Query Frame = 2
Query: 584 KLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLP-----INVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSV--HDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTF--SMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAI--KDNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQ-GIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPP 2521
+L + +DRET +L + D P T ITI I D NDN P F Y ++ E L P +N++A D DSG+ G + Y S ++T V ++I+S G + + +++ + Y+F +A D GQ + V I I D N+ P K+ ++ IF N + + + V+ D D+ NG+ L K LF + + + F + I D+G P L ++ ++I ++ D+ P F PA SI E+S +G+ +T VRA + +Q+ Y I + F ++ ++ D LD E F + +V + G +L+ + + IN+ID N+ P F+ S + ED KPR + + +D D G N ++T +I + F I S G + + +LDRE + L + D G P + V + + DLNDN P+F PL ++V+ + ED +GA ++ + D D++S +L LKS GI L V D+ S+ +I+ + P++ + + + KI+ + VI+ I V SFI I ++ + PP
Sbjct: 1701 ELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISE------LTPPGTSILNLTASDKDSGSNGNIVYTLS-NDTYGV---YSIDSRTGIV--YSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAP--QFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLF---VVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPA-RVSIPENSKVGSYITTVRARASSD---AQVTYSI----ISGNKGRAFYVDPFTGVISVASAD-ALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAF-----KPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTDSGIP----PKSTNCQVKVVVTDLNDNPPLFD---PL-SEVNIR------------EDTRTGA-----------VVTSVVATDTDKES-RLTYNLKSASTPGIAILRVSATDQD---SGSNAQIKYSF----PITNSDQIDY-----KIDADTGVISARRTIDVRIRDSFIQIP-VQAMDQGVPP 2287 HSP 15 Score: 105.145 bits (261), Expect = 8.046e-23 Identity = 104/395 (26.33%), Postives = 179/395 (45.32%), Query Frame = 2
Query: 587 LKLKSSIDRETNDR-IELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSG-NFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPA-TSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDRLLDGEI-FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVP 1756
+ + +ID D I++ + D G PP ++ ++I+ + P F Y + EN + + + + V D +G G++SY SN +F I +G I + K LDY++ + + VV A D P+ V IN+ DVNDE P+ + + + E + +V+VS D D G NG+ F I F + +I + D E + ++ D G P + + +T+ ++D+NDN P F +P +LE+ P+ + + ++ A D+D G N++L + + T Q FLI+ +G L N D +S+ + +D G P LS+ I I +N+ D + P FN+ + F VP
Sbjct: 2259 ISARRTIDVRIRDSFIQIPVQAMDQGVPPQ--RALVYVRIIITRE--PKFELPSYFGKVPENAMMGTSV-LTVRVTDNAAGLPLGRISYNIENSN------YFRIGQRSGVISVNKPLDYET--KRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGYMAQWS--EGIPVGTIVVNVSAADKDSGANGRV-WFAIQSGDDKGSFAIDRKTGVI---RTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRLYEINATDRDSGANARLSFTVIG--GTGQGL--FLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVP 2630 HSP 16 Score: 87.4261 bits (215), Expect = 2.271e-17 Identity = 105/423 (24.82%), Postives = 194/423 (45.86%), Query Frame = 2
Query: 1253 LMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNG----NLLVNQH---LDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI----SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLN--DLNDNSPIFHRNFPLPT--KVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSID----RDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVL 2461
+ K DREK + AY +T ++ P S + V + D+NDN P+F + TS ++ K+ A+D D G NS Y I N +++G +L+VN +DR LD + + + SD G PA + ++I + D N+ P F+ ++ T+PE+ + +I ++ SD D G NA++ +I+ + + I G++ + LD E K Y + + A D H ++ S ++ + D+NDN+P+ H ++ L +V+ + ++ + V D DSG N V+++++ G YFS+ D + + + L E L + D+G PP+++ +I + D +PK H E+ ++ + V T+ I++ +
Sbjct: 14 ITTKTVLDREKVS-AYN-LTIVEFSTPP--KSYTVLVYVQDLNDNSPSF-VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLYADLVVNASSIGVDRERLDSYVLN--ISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYSGTIPEN-------IDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKA----EDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGG--DGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYET--RVWENATVNTLVAIVNAV 414 HSP 17 Score: 77.7962 bits (190), Expect = 2.284e-14 Identity = 64/221 (28.96%), Postives = 108/221 (48.87%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFST-HKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLII 1246
++ + ++D ET + + TD GSPP+ + +TI++LD+NDN P F + + EN LNS L ++A D DSG +LS+ + T + F I+ +G + + DY++ YS + A D G P LSS+ T+I+N+ D ++ P S N+ + N + + + V+ D D G G+ F + + K N + II
Sbjct: 2464 IRTQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLENLPLNSRL-YEINATDRDSGANARLSFT-VIGGTG--QGLFLIDKFSGWLTTNITFDYENTAVYQYSLTIKATDAGNPPLSSNITIIVNVADEDEYDP--SFNRMDYKFDVPGNAKIGDFVGQVTATDRDSGDQGR--VFFVFYNPTSNALKMNATTGII 2676
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO48237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKF4]) HSP 1 Score: 191.045 bits (484), Expect = 2.383e-49 Identity = 180/665 (27.07%), Postives = 294/665 (44.21%), Query Frame = 2
Query: 386 DNAPHWPKPIE-LSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXX----XXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLI-ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKG-VNAQLTLAIKDNINK-FQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
+N P + + E S+SE+A +GT+ A D D ++YF + + + K +DRE DR + D G P L G +TI +LDVNDN P F + Y + E+ + + + V A D DSG+ G++ K+ + N+D F+I +G + ++K LD + +Y+ V A D G P S++ TV I ++DVND P S K + TI E+ +N+ + V D DQG NG+ F G D+ F + I ++ K K D E +T D G P L + + + ++DVNDN P F I E+ +G +V+A DKD G N ++ + N + PF I E+ G + + + LDR + F+ + D G P +ITI L+DIN+ PP F+Q +H ++ E+ ++ + D D G N ++ ++ F+I+ G++ L+ K Y ++ A DG + T V + + D N ++P F R +V + ++ + D+D+G+NA + SI + P FS+D +K L E ++ V D G P + + I I D
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFSI-------DQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKSIGDFV-LAVRASDADSGSNGEV--KYCILNSDGDNSAFSIGEVSGAVTVMKKLDRE--KVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFS--KKVYSATIREDVPVNQLVTTVRATDCDQGSNGEV--FFEIVSGNDMNFFS--INRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSF----MQNDL--PFSINENTGGISIKEELDREKVPK-FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQ-------VKAIDPDSGPTNVVYSIVSSSGHDRCFRINPQGLITLSCTLNYNTKHVYVFSVSASDGM------LSSTALVYVNVTDSNTHAPEFKRR-SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI--ATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIAD 638 HSP 2 Score: 162.54 bits (410), Expect = 1.918e-40 Identity = 161/591 (27.24%), Postives = 255/591 (43.15%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVP-KPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVT-----GSVVIFLNDLNDNSPI---FHRNF-----PLPTKVSYK 2101
D+NDNAP + + I EN +G F A D D + F LP + +K +DRE + I D G P G ITI +LD+NDN P FS +Y S+ EN + + + + V A+D DSG + +S+ ++ R F IN G I L +L+Y++ + Y F V A D LSS+ V +N+ D N P + + E+ +L ++ V D D G N + + L + D + DREK +T D+GIP L + + + I DVNDN P F P+ + E G V +V A D D G N+Q+IY + F + + G + + LDR E + + VV +D G P +++ + L D+ + PP+F + + TVPED P++ K ++ D ++ ++ F I+ N G +Q++ LD E + EY+LT +R T++ +V+++L D+NDN+P+ FH N +P + YK
Sbjct: 331 DVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFS--------FMQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSV-LQVKAIDPDSG---PTNVVYSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKH--VYVFSVSASDG---MLSSTALVYVNVTDSNTHAP--EFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKIS------YSIATLVPEFSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFT--IDSTQGIIRTLKPLDRETIPE-YELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKS------QDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLT-----------VRATLSPFFTETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYK 875 HSP 3 Score: 157.532 bits (397), Expect = 6.918e-39 Identity = 169/648 (26.08%), Postives = 296/648 (45.68%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQG-INGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLI-ESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIK---DNINKFQI-SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYV--RHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIV 2290
D+ND P + K + +I E+ + L A D D+ + + S D+ F + + ++++K +D E L++ D G P L + + I ++DVNDN P F + + + EN+ + V A D D G G++++ ++ F+IN G I + + LD + + ++F + A D G P + + I ++D+ND P S + +I EN+ ++ V D D G N ++ ++ G D F+ N LI + K + + +++ D G+ L+S+ L+ V + D N + P F + S + E + +GT V V A D+D G N+++ Y I+ + P F + E+ G + LDR + + V +DHG P L + + I++ D+N+ PVF + ++ V ED + P R I ++ SD D G NAQ+ + D F I S G+++++ LDRE EY+LT++A D GTP Q + V + L D+ D+ P+F + PL +V+ E R +I + + +D + SI G F I+ + +++ KL E Q ++L V
Sbjct: 226 DVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV----SGNDMNFFSINRING--EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEF-YRVQAYDKDHGTNGEITFSFMQNDLP-----FSINENTGGISIKEELDREKVPK--FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEE--YHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYS--IVSSSGHDRCFRINPQGLITLSCTLNYN---TKHVYVF-SVSASD-GM--LSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIA------TLVPEFSVDETTGVIKTAGSLDR-EKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVRED------IRPGGRVI-EVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ----ASVKVKVILEDVKDSPPLFEK--PL-YEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRLTV 827 HSP 4 Score: 109.768 bits (273), Expect = 3.765e-24 Identity = 103/350 (29.43%), Postives = 159/350 (45.43%), Query Frame = 2
Query: 1382 DNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIES-NGNLLVNQHLDR-LLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIG----YIAVSDCDKGVNAQLTLAI----KDNINKFQISH-NGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
+N P FS S+ E + +GTVV V A D D G N + Y +S P F I+ G + + LDR LD F V D G P+L +++TIN++D+N+ P+F ++ + +PED S IG + SD D G N ++ I DN + F I +G + + LDRE+ Y L + A D G P + T +V I L D+ND +P F +K Y +R ++ + D D G+N V I G +FSI+R V++ +KL E G+ L+V +D+G+P + + I + D +P+
Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMS-PSQNLMSATYFSIDQITGVITTKRGLDREFLDRHFFRV--KAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNIYAADIPEDKS-----------IGDFVLAVRASDADSGSNGEVKYCILNSDGDN-SAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPP----RSATVTVKITLLDVNDCTPQF-------SKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQ 338
BLAST of Protocadherin vs. Ensembl Nematostella
Match: EDO34815 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN97]) HSP 1 Score: 180.644 bits (457), Expect = 8.099e-47 Identity = 158/574 (27.53%), Postives = 266/574 (46.34%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLII---YQLMAKHKFDREKEAFAYT------TITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIE-SNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN-INKFQISH-NGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPI 2059
D NDN P + P I+ +ISE A IG A D D + F++ +++ S+DRE L + D P G G +T+ + DVNDN P F+ + + + E + S++ +N +A D D G+ ++Y S FAINS G + + + LD ++ + +YSF V A D G L S+ V + I D ND P + D+ + + ++ V+ D D G NG H + +L L +I+ + K DRE+++ YT ++ D+G+ TS L+ + + D NDN P F+ S ++LE+ P+GT VT V A D+D G+NSQ++Y ++ F IE S G + + + ++R E + V + SD G P LS+ ++ ++++D+N+ PPVF + T+ E + V + + +D D N +T I + F I+ G++++ VL+RE K+ Y L ++A D + + G++ + + D NDN+PI
Sbjct: 326 DANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGSEGKFEIG-------RSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVI-VNATATDPDQGSNAAITYSMSYPG-------FAINSNTGSVTITRPLDRET--KQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDV--IDRTPVGTIVLAVNAEDRDVGNNG--------HVTYAILI---LPFIIVPDTGNINTSSKLDREQQSL-YTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGDGV------FSIEPSTGQIRLQKAINREAK-ENYHVTITASDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQ------VNATDADVERNGHVTYTIMHGALGMFTINETTGVIRTQGVLNRESKDFYTLIVMARD---QGAVPYMDFGTIDVHVIDKNDNTPI 850 HSP 2 Score: 169.088 bits (427), Expect = 3.866e-43 Identity = 176/677 (26.00%), Postives = 294/677 (43.43%), Query Frame = 2
Query: 377 DLNDNAPHW-PKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSP-PLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI-SHNGMLQSVAVLDREEKEEYKLT--LIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR---------NFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDD 2356
DLNDN P + P ++ EN+ +GT A D D + S F +++ ++DRE ND L I TD G P T I ++ILD NDN P FS +Y S++EN + + S + D ++ ++ +DS++ FA+N G I R+ D +Y+F V+A D S V+I+++D ND P + S++ TI E ++ + + V+ +D D G+NG+ F + G + F+ SD ++ DRE +A ++ D +TV + DVNDN P F+ PA + + E +G+V+ A D D+G N+ + Y +S +P F I SN G++ + + LDR + +S V D G L + + + + + D N+ P F + +D + P + + D D G N +T AI I F I G + + + LDRE++ Y L ++ + T + T + I + D NDN P F++ N P+ TKV+ + D+DSG N+ + S+ G FSI+ ++L + + E + + + + DRG P SS ++ + + D
Sbjct: 106 DLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGL---FRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYRLNGSDSIQ--FAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRF-IPSSIQS-TISEAASIGQSVARVTANDPDSGLNGR--IFFSINSGSEGKFEIGRSDGVV---RVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMS--------YPGFAINSNTGSVTITRPLDRETK-QAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQ-------TDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAIL--ILPFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTM----------VTARDEDSGINSQIMYSLTGG--DGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVLSSDAKVHVHVLD 738 HSP 3 Score: 155.221 bits (391), Expect = 1.172e-38 Identity = 149/571 (26.09%), Postives = 255/571 (44.66%), Query Frame = 2
Query: 725 PTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRH--FAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIP-SLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGT---VVTKVRALDKDEGLNSQLIYHIS---------DPRT---TNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNI-NKFQISH-NGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPK 2377
P F+ Y + E +L V A D D G G + Y N + + F ++ G I+ ++L+ SY+ + A DHG P+ S++T V I + D+ND P+ N + T+FEN+ + ++DV+ D D G N + + + LF+ + DRE F TIT D G+P S T+ + V I+D NDN+P FS + SI E+S G + + + A D+D N+ + Y ++ +PRT T ++ PP ++ +R + ++ V+ +D + E+ I+++D N+ P F S+ T+ E S +++ + +D D G+N ++ +I KF+I +G+++ LDRE K Y L + AIDG+ + + G+V + L D+NDN+P F + VS V ++ D D G+NA + S+ P F+I+ + SV + R L E + + V +D G S++ + + I D SP+
Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLDPNTGMIKTARNLERQQ--TFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPV--FNPTNYSTTVFENSPVGTSLLDVTATDADSGQNA-YVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGPGVPVQMASSIMATDRDIESNADVRYRLNGSDSIQFAVNPRTGVITTRVSPPPSLDH----------ERTTN---YTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAAS-------IGQSVARVTANDPDSGLNGRIFFSINSGSEGKFEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGY---GTVTVTLQDVNDNTPKFTKP-AFNVDVSEGVAVGSVIVNATATDPDQGSNAAITYSMS----YPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQ 536 HSP 4 Score: 144.05 bits (362), Expect = 3.169e-35 Identity = 149/580 (25.69%), Postives = 257/580 (44.31%), Query Frame = 2
Query: 602 SIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDRE-KEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVI-----VVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQIS-HNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPP 2317
S+D E ++ D + I +LD NDN P F ++ E + + V+A D DSG G++ + S+++ K F I ++G +R+ SLD ++ + Y V A D TV + + DVND P K ++ + E + IV+ + D DQG N + + + GF + N + I + + DRE K+A+++T + D G L S+ + V I D NDN P F +++ +P+GT+V V A D+D G N + Y I + P ++ GN+ + LDR +++++ + V+DHG ++ + I++ D N+ P FNQS + TV E+ +P+ K + + D D G+N+Q+ ++ F I G ++ ++RE KE Y +T+ A D GTP + + V + + D+NDN P+F T ++ + D D N V +I G + F+I+ ++ L E + + LIV+ +D+G P
Sbjct: 291 SLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVA-RVTANDPDSGLNGRIFF--SINSGSEGK--FEIGRSDGVVRVSGSLDREA--KAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTP--KFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNAAI-TYSMSYPGFAI--NSNTGSVTITRPL-----DRETKQAYSFT-VHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAI-------LILPFIIVPDTGNINTSSKLDREQQ-SLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLEN----MPVGTK---VTMVTARDEDSGINSQIMYSLTGGDGVFSIEPSTGQIRLQKAINREAKENYHVTITASDRGTPVL----SSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTIMHGALG-MFTINETTGVIRTQGVLNRESKDFYTLIVMARDQGAVP 830 HSP 5 Score: 124.405 bits (311), Expect = 5.169e-29 Identity = 164/680 (24.12%), Postives = 289/680 (42.50%), Query Frame = 2
Query: 587 LKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTV-IINIVDVNDELPIISLNKSLKDITIFENNNLNEPI-VDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKH-----------KFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAV----SDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLS--IKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLI-----VIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVD 2551
+K +++R+ L I D G P + ++I + D+NDN P F+ Y ++ EN + + L ++V+A D DSG ++Y + ++ + R S +G I + +LD + N+ Y+ + A D G P ++ + ++ I+D ND +P S + +I EN+ P+ + S+ D+ I D+ ++ N SD I + + + D E+ + D S + + ++D NDN P F + +I E + IG V +V A D D GLN ++ + I+ + F + S+G + V+ LDR ++ + V D +T+ L D+N+ P F + F+ V E + +G + V +D D+G NA +T ++ F I+ N G + LDRE K+ Y T+ A DG + V +V + + D NDNSP F T V + V ++A+ ED+D G N V + I P II P D ++ + KL E Q ++ L+ + D G +S + I++ D FN+++ + N+ A ++ + +G+ +T+V + I Y L D
Sbjct: 66 IKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTTVFENSPVGTSL-LDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAGNLDREV-NDF-YNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTG--SIQENSGPGVPVQMASSIMATDRDI----------ESNADVRYRLNGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSIN--SGSEGKFE--IGRSDGVVRVSGSLDREAKA-VYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVA-----------VGSVIVNATATDPDQGSNAAITYSMS--YPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDGG---GLESNV--AVNVEIGDENDNSPQFP-TVQYQTDVIDRTPVGTIVLAVNAEDRDVGNNGHVTYAILILPFIIVP------DTGNINTSSKLDREQQSLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTD-----------FNDNQPQFNQSEYS---ATVLENMPVGTKVTMVTARDEDSGINSQIMYSLTGGD 686
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 267.314 bits (682), Expect = 4.156e-74 Identity = 223/770 (28.96%), Postives = 354/770 (45.97%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD--------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL-AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY---KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN S + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSLTS+ + V + D NDN P FS S E++ G VT V A D D G N+++ Y + + N +F + +G++ VN +LDR E + V+ D G L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA++ L ++ + G + S DRE+K Y + A+DG + T +V +F+ D NDN+P FP+ + + VR + + D D+G NA ++ SI G F ID + L KL+ +H G+H+L+V D G+P +S++ + + ++++ LS +V ++ ++K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 131 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPI-LQLKAADADVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREEVSQL--RFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVGDVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDS--SVNGIFS--IDSDSGDIRVNTNLDREQK-ERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSP-------VGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDREQKTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTV--TFPINSSYTLLPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFRLFEIDGATGVISLMAKLEQKHYGLHRLVVQVTDNGQPSQSTTTLVHVYVNET--LSNSTIVETQVARSLSTSLNTNIAGDPNYDLSKQRLSIVIGVVSGIMTVILIILVVVMARYCRPKNK 877 HSP 2 Score: 135.191 bits (339), Expect = 9.132e-32 Identity = 160/631 (25.36%), Postives = 266/631 (42.16%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDS------------VKRHF-------------AINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN-----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGS--VVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDL-----------SIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N ++ KR F ++T+GE +LI D SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE+ + T+ D G P + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E N L + LD E ++V++V D G P+L++ + + + D N+ PP+F+++ + PE+ + P R + + +D D G NA+++ ++ ++N F I S +G ++ LDRE+KE Y+ +IA D + +T+ GS VV+ ++D NDN P F ++ + YV+ L + V D D G NA + L + G I S DR E + + V D G PP+S++ + + + D +P N S
Sbjct: 129 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNP--RFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVG-DVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQE-YNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNA------PGER-VTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKD-----KGINTLQGSATVVVLVDDKNDNEPKFMQDV-------FTFYVKENLDPNSPVGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDR-------------EQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSS 717
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 266.159 bits (679), Expect = 4.333e-74 Identity = 223/770 (28.96%), Postives = 354/770 (45.97%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD--------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL-AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY---KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN S + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSLTS+ + V + D NDN P FS S E++ G VT V A D D G N+++ Y + + N +F + +G++ VN +LDR E + V+ D G L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA++ L ++ + G + S DRE+K Y + A+DG + T +V +F+ D NDN+P FP+ + + VR + + D D+G NA ++ SI G F ID + L KL+ +H G+H+L+V D G+P +S++ + + ++++ LS +V ++ ++K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 131 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPI-LQLKAADADVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREEVSQL--RFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVGDVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDS--SVNGIFS--IDSDSGDIRVNTNLDR-EQKERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSP-------VGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDREQKTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTV--TFPINSSYTLLPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFRLFEIDGATGVISLMAKLEQKHYGLHRLVVQVTDNGQPSQSTTTLVHVYVNET--LSNSTIVETQVARSLSTSLNTNIAGDPNYDLSKQRLSIVIGVVSGIMTVILIILVVVMARYCRPKNK 877 HSP 2 Score: 134.42 bits (337), Expect = 1.734e-31 Identity = 160/631 (25.36%), Postives = 266/631 (42.16%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDS------------VKRHF-------------AINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN-----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGS--VVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDL-----------SIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N ++ KR F ++T+GE +LI D SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE+ + T+ D G P + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E N L + LD E ++V++V D G P+L++ + + + D N+ PP+F+++ + PE+ + P R + + +D D G NA+++ ++ ++N F I S +G ++ LDRE+KE Y+ +IA D + +T+ GS VV+ ++D NDN P F ++ + YV+ L + V D D G NA + L + G I S DR E + + V D G PP+S++ + + + D +P N S
Sbjct: 129 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNP--RFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVG-DVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQE-YNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNA------PGER-VTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKD-----KGINTLQGSATVVVLVDDKNDNEPKFMQDV-------FTFYVKENLDPNSPVGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDR-------------EQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSS 717
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 266.929 bits (681), Expect = 7.081e-74 Identity = 223/770 (28.96%), Postives = 354/770 (45.97%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD--------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL-AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY---KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN S + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSLTS+ + V + D NDN P FS S E++ G VT V A D D G N+++ Y + + N +F + +G++ VN +LDR E + V+ D G L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA++ L ++ + G + S DRE+K Y + A+DG + T +V +F+ D NDN+P FP+ + + VR + + D D+G NA ++ SI G F ID + L KL+ +H G+H+L+V D G+P +S++ + + ++++ LS +V ++ ++K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 131 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPI-LQLKAADADVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREEVSQL--RFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVGDVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDS--SVNGIFS--IDSDSGDIRVNTNLDREQK-ERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSP-------VGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDREQKTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTV--TFPINSSYTLLPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFRLFEIDGATGVISLMAKLEQKHYGLHRLVVQVTDNGQPSQSTTTLVHVYVNET--LSNSTIVETQVARSLSTSLNTNIAGDPNYDLSKQRLSIVIGVVSGIMTVILIILVVVMARYCRPKNK 877 HSP 2 Score: 135.191 bits (339), Expect = 1.101e-31 Identity = 159/631 (25.20%), Postives = 268/631 (42.47%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDS------------VKRHF-------------AINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN-----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGS--VVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDL-----------SIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N ++ KR F ++T+GE +LI D SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE+ + T+ D G P + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E N L + LD E ++V++V D G P+L++ + + + D N+ PP+F+++ + PE+ + P R + + +D D G NA+++ ++ ++N F I S +G ++ LDRE+KE Y+ +IA D + +T+ GS VV+ ++D NDN P F ++ + YV+ L + V D D G NA + L + G I S DR++++ + V D G PP+S++ + + + D +P N S
Sbjct: 129 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNP--RFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVG-DVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQE-YNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNA------PGER-VTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKD-----KGINTLQGSATVVVLVDDKNDNEPKFMQDV-------FTFYVKENLDPNSPVGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDREQKTT-------------YTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSS 717
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh7b (protocadherin 7 [Source:NCBI gene;Acc:101166584]) HSP 1 Score: 266.929 bits (681), Expect = 7.354e-74 Identity = 223/770 (28.96%), Postives = 354/770 (45.97%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLD--------------------------RXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNK----SLKD--ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNL---SDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTL-AIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSY---KEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKE---------------KINKEMIVITIAVIISVLALGSFITIVIIK--CRKKAK 2515
D+NDN P +P P+ LS+ EN IGTL+ +P A D D + K+ + +SS F+L T D + P+L +K ++DRE D EL + + D G PP + + I+ + I DVNDN P F Y L EN S + + + A D D G G++ Y + T+SV+R ++ + G + ++ +D + ++L F V+A D GQP TV++NI D ND +P I + K LKD + E+ ++ PI V V D DQG NG C ++G F L + + Y L D E I D G PSLTS+ + V + D NDN P FS S E++ G VT V A D D G N+++ Y + + N +F + +G++ VN +LDR E + V+ D G L + + + D N+ P F Q F F V E+ + P +G + V D DKG NA++ L ++ + G + S DRE+K Y + A+DG + T +V +F+ D NDN+P FP+ + + VR + + D D+G NA ++ SI G F ID + L KL+ +H G+H+L+V D G+P +S++ + + ++++ LS +V ++ ++K+ + I I V+ ++ + I +V++ CR K K
Sbjct: 135 DINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNPRFEKSVYEADLPENSSPGSPI-LQLKAADADVGVNGQIEYVFGAA-TESVRRLLRLDESTGWLSVLHRIDREEVSQL--RFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVGDVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQEYNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNAPGERVTTVTATDADSGKNAEISYSLDS--SVNGIFS--IDSDSGDIRVNTNLDREQK-ERYEFKVIAKDKGINTLQGSATVVVLVDDKNDNEPKFMQDVFTFYVKENLDPNSP-------VGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDREQKTTYTFRVKAVDGG---DPPRSATATVSLFVMDENDNAPTV--TFPINSSYTLLPPSSTVRTVVRTVIATDTDTGINADLNYSIIGGNPFRLFEIDGATGVISLMAKLEQKHYGLHRLVVQVTDNGQPSQSTTTLVHVYVNET--LSNSTIVETQVARSLSTSLNTNIAGDPNYDLSKQRLSIVIGVVSGIMTVILIILVVVMARYCRPKNK 881 HSP 2 Score: 135.191 bits (339), Expect = 1.113e-31 Identity = 160/631 (25.36%), Postives = 266/631 (42.16%), Query Frame = 2
Query: 701 ILDVNDNYPTFSTHKYIISLRENFQLNS--LLPINVSAVDCDSGNFGKLSYKHSVSNTDS------------VKRHF-------------AINSTNGEI--RLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFN-CFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATS--------FSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGN-----LLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINK-FQI-SHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGS--VVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHEL------IALFVEDKDSGANAVVDL-----------SIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNES 2401
ILD+NDN P+F + +S+ EN + + LLP +A D D G G Y+ N ++ KR F ++T+GE +LI D SY + D G P SS + + I DVND P KS+ + + EN++ PI+ + D D G+NGQ F + L + + S + L H+ DRE+ + T+ D G P + + I D NDN+P + ++ E + T + V+ D+D+G N + + Q+ P +E N L + LD E ++V++V D G P+L++ + + + D N+ PP+F+++ + PE+ + P R + + +D D G NA+++ ++ ++N F I S +G ++ LDRE+KE Y+ +IA D + +T+ GS VV+ ++D NDN P F ++ + YV+ L + V D D G NA + L + G I S DR E + + V D G PP+S++ + + + D +P N S
Sbjct: 133 ILDINDNTPSFPSPVLTLSVEENRPIGTLYLLP---TATDRDFGRNGIERYELIQDNGENSRRSGSSGDSYSGKRRFDEGASRSSVFELQVADTTDGEKQPQLIIKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVMITDVNDNNP--RFEKSVYEADLPENSSPGSPILQLKAADADVGVNGQIEYVFGAATESVRRLLRLDESTGWLSVL---HRIDREEVSQLRFTVMARDRGQPPKMDKATVVLNIKDENDNVPAIEIRKIGRIFLKDGVANVAEDVVVDTPIALVQVSDRDQGENGIVTCTVVG-DVPFQLKPASEMEGEQNKKKYFLHTSAPLDYETTQE-YNVVIVAVDSGSPSLTSNNSLLVKVGDTNDNPPIFSKNVVQVSFPENNA------PGER-VTTVTATDADSGKNAEISYSLDSSVNGIFSIDSDSGDIRVNTNLDREQKERYEFKVIAKD-----KGINTLQGSATVVVLVDDKNDNEPKFMQDV-------FTFYVKENLDPNSPVGMVTVIDADKGQNAEMGLFIEEEEEIFSIENETGTIFSTLSFDR-------------EQKTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTFPINSS 721
BLAST of Protocadherin vs. Ensembl Medaka
Match: pcdh1b (protocadherin-1 [Source:NCBI gene;Acc:101174755]) HSP 1 Score: 245.743 bits (626), Expect = 2.524e-67 Identity = 213/693 (30.74%), Postives = 321/693 (46.32%), Query Frame = 2
Query: 377 DLNDNAPHWPKPI-ELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXX--XSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYK-HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDI------TIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTT--------------ITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHE-----LIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDS 2359
D+NDN P + PI LSI EN GTLF+IP AVD D + F L DE + P++ + ++DRE D +L I + D G PP ++ I + D NDN P F ++Y L EN + + V A D D+G G + Y H S D+V+R I+ + G I + +D + N L F VVA D G + SS V I+I D ND P I + I I E+ + P+ V V D D+G N C + G F L + ++ DR+++ F TT I D G P+L+S+ + V + D+NDN P+FS + E + G V V A D D G+N++L+Y I + + F I SN G + V LDR D E + V +D G P+ + + IN+ D N+ P F S + F+V E + PL P +G + VSD DKG N+Q+TL ++ + KF I + G + S DRE++ Y L A+D G P R + G V I + D NDN+P + P SY + + ED D+G NA + +I G F I + +KL + +H+G+H+L+V D+G+PP+ ++ + + ++++
Sbjct: 143 DINDNTPQFSSPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDE-KIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSV-LQVRANDADTGANGDIDYSLHQAS--DTVQRLLRIDRSTGIIYVKGLVDREEDNLL--KFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQL------------RPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASL----FEINSNTGEIRVRNQLDR-EDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNE---NMPPLNP----VGVVTVSDADKGENSQVTLFVEPDNGKFIIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPP---RSSYVG-VTINVLDENDNAPYVTK----PANSSYTHLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPPRHTTALVHVYVNET 797 HSP 2 Score: 148.288 bits (373), Expect = 7.479e-36 Identity = 185/651 (28.42%), Postives = 281/651 (43.16%), Query Frame = 2
Query: 605 IDRET---------NDR--IELVILLTDS----GSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNG------EIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDL---LFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSF--------SILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEI---FSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPED--PSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDN--INKFQISHN-GMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIF---------HRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP-----------GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSP 2374
IDRET +D+ +E + +TD G P EGII ++LD+NDN P FS+ +S+ EN +L I V AVD DSG+ G Y ++S + F + ++ +I +LD + + SY + D G+P +SS + I + D ND P K+ + + EN+ ++ V +D D G NG + L H+ D L + + S IIY K DRE++ + D G S +S +T+ I D NDN P + +I E PIGT V V+ D+DEG N+ ++ + Q+ P ++ LLD E + + +V D G PALS+ + + + DIN+ P F+ + ED P D + I +A +D D GVNA+L +I ++ + F+I+ N G ++ LDRE+ E Y+ + A D G P T T VVI + D NDN P F + N P V + V D D G N+ V L ++P G I S DR+++S R LK+ D G PP+SS + + I + D +P
Sbjct: 96 IDRETLSDCRNLFEDDKCFLEFEVSITDMVKGIGLGPRLIEGII--EVLDINDNTPQFSSPILTLSIPENTHTGTLFSIPV-AVDRDSGSNGVAEY--ALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKD--SYDLNIRVVDGGKPPRASSALLRITVTDQNDNAP--KFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSL--HQASDTVQRLLRIDRSTGIIY---VKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENA-VVTCVVAGDVPFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPALSSTNSLKVQVTDINDNTPSFSPALLEVNFAEDNQPGDKV--------IDVVA-TDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVP----SKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVG----------VVTVSDADKGENSQVTLFVEPDNGKFIIQNGTGTILSSISFDREKESTYTFR-LKA------------VDAGDPPRSSYVGVTINVLDENDNAP 695 HSP 3 Score: 135.576 bits (340), Expect = 6.032e-32 Identity = 137/511 (26.81%), Postives = 233/511 (45.60%), Query Frame = 2
Query: 593 LKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLN--SLLPIN-----VSAVDCDSGN--------FGKLSYK---HSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESN-GNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDIN-NCPPVFNQSTFHFTVPEDPSDHL-PLVPKPRNIGYIAVSDCDKGVNAQL--TLAIKDNINKFQISHN-GMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDN 2050
+K +DRE ++ ++ ++ D G + + +TI I D NDN P + + +NF N +PI V D D G G + ++ S S D +++F ++ LDY+ + Y +VA D G PALSS+ ++ + + D+ND P S + +L ++ E+N + ++DV D D G+N + + I LF+ N + ++ +++ DRE + D G+PS T + ++ + + D NDN P F + SFS+ E+ P V V D D+G NSQ+ + +P F+I++ G +L + DR + ++ + D G P S+ + +TIN++D N N P V + +T HL P P + + D D GVNA+L T+ + FQISHN G ++ + K ++L + D G P RHT T V +++N+ +N
Sbjct: 324 VKGLVDREEDNLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISEDMPIGTPVALVQVSDRDEGENAVVTCVVAGDVPFQLRPASESANDRKRKYF--------LQTTTLLDYERIKD--YRIEIVAVDSGNPALSSTNSLKVQVTDINDNTP--SFSPALLEVNFAEDNQPGDKVIDVVATDADSGVNAEL-VYSIIESSAASLFEINSN---TGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFMLSGYSFSVNENMPPLNPVGVVTVSDADKGENSQVTLFV-EPDNGK-----FIIQNGTGTILSSISFDREKE-STYTFRLKAVDAGDPPRSSYVGVTINVLDENDNAPYVTKPANSSYT-------HLKPSSPPDTPVEVVKAEDIDAGVNAELYYTITGGNPHGLFQISHNSGEIKLAQGFTGKHKGLHRLVVRVSDKGKPP---RHT-TALVHVYVNETTNN 800 HSP 4 Score: 127.102 bits (318), Expect = 2.933e-29 Identity = 128/478 (26.78%), Postives = 209/478 (43.72%), Query Frame = 2
Query: 1025 IINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLS---DLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFN--------QSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQI----------SHNGMLQSVAVLDREEKEEYKLTLIAID-GTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKE--YVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMV 2386
II ++D+ND P S + ++I EN + D D G NG L + LF ++ D I Q++ DREK+ I D G P SS L+ + + D NDN P F + E+SP G V +VRA D D G N + Y + T Q + S G + V +DR D + VV D G + S++ ++TI++ D N+ P F + ED +P + + VSD D+G NA +T + ++ FQ+ LQ+ +LD E ++Y++ ++A+D G P + + T S+ + + D+NDN+P F P +V++ E ++I + D DSG NA + SI A F I+ + +++ +L E ++ V D+G P K+ + + I ++D PK M+
Sbjct: 138 IIEVLDINDNTPQFS--SPILTLSIPENTHTGTLFSIPVAVDRDSGSNGVAEYALSAGPDANQLFGLQVAEDVDEKIPQVIVIGNLDREKKDSYDLNIRVVDGGKPPRASSALLRITVTDQNDNAPKFEKNQYEAELPENSPPGHSVLQVRANDADTGANGDIDYSLHQASDTVQRL-LRIDRSTGIIYVKGLVDREED-NLLKFYVVARDRGPNSKSSKAQVTISIKDQNDNAPAIEIRGIGLVIHQNFVANISED-------MPIGTPVALVQVSDRDEGENAVVTCVVAGDV-PFQLRPASESANDRKRKYFLQTTTLLDYERIKDYRIEIVAVDSGNPAL----SSTNSLKVQVTDINDNTPSFS---PALLEVNFAEDNQPGDKVIDVVATDADSGVNAELVYSIIESSAASLFEINSNTGEIRVRNQLDREDVERYEFGVAAADKGVPSKTGTAIVVINVEDRNDNDPKFML 596
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000044242.1 (SMESG000044242.1) HSP 1 Score: 1730.69 bits (4481), Expect = 0.000e+0 Identity = 890/895 (99.44%), Postives = 892/895 (99.66%), Query Frame = 2
Query: 77 MSIIDRDSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTLEYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISDMDISMNFKVFNEENCMECQRIKTQNDLIQNHNKLCLSSVYDIKQPSVMPDNLISCFLSP 2761
MSIIDRDSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTLEYCMTKLFIIINNVIVKVINIIINDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRTKKNKQITYKIKKQSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFA+TTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSV VVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREE EEYKLTLIAIDGTPDVQIRHTVTGSVVI LNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISD+DISMNFKVFNEENCMECQRIKTQNDLIQNHNKLCLSSVYDIKQPSVMPDNLISCFLSP
Sbjct: 1 MSIIDRDSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTLEYCMTKLFIIINNVIVKVINIIINDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRTKKNKQITYKIKKQSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAHTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVTVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREENEEYKLTLIAIDGTPDVQIRHTVTGSVVISLNDLNDNSPIFHRNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISDIDISMNFKVFNEENCMECQRIKTQNDLIQNHNKLCLSSVYDIKQPSVMPDNLISCFLSP 895
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000070713.1 (SMESG000070713.1) HSP 1 Score: 416.772 bits (1070), Expect = 4.416e-129 Identity = 301/878 (34.28%), Postives = 461/878 (52.51%), Query Frame = 2
Query: 80 SIIDRDSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTL--EYCMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKDITIF----ENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHR--NFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKP-GIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLS-PKNMVHF----NESKEKINKEMIVITIAVIISVLAL------GSFITIVIIKCRKKAKPPLICYELENVDKKAVSMPEISD-----MDISMNFKVFNEENCMEC 2638
S D +T+SV+E PV +++L+N L + N++ F+ L+ YFRL+ G I + LD DND LC + + C T + + + V + I+INDLNDN P W +SI+EN+ I ++P A+D D + + K F+L + + PKL +K+++DRE L + D P TG ++ I+I D NDN P F Y +S+ ENF +++ LPI+ +A+D DSG FG++SY S++ + VK F+I+ +G+I + K++DYDSG L Y F++VA D G PA SS+ ++II I DVND+ P I++ + F ENN N + ++V D D G G+FNC L F + F + L + IYQL+ FDRE E+ +T I C D G P S +LITV I D+NDN P FS F E + + V +V D D G NS++ Y I +T+ PF I++ G + +DR + F +V D G P L++ +E+ I +IDIN+C P+FN++ + F + E+ L P +IG + +DCD G N ++T + + NKFQIS G+L+ + +DRE + Y T++AID P R+T T V I ++D NDN P+F + N P KVSY+E + E+ + +D D G NA++ IK + F ID S+ + ++L S HQG L ++ D G P SS +E++I IDDS P S P N F N+ I V+ A++ISV+ L S V + + P+ + + K +S + +D +++S NF + N + C
Sbjct: 19 SQFDSTILTISVDENTPVGRKISNLRNELKLN-NTNVTFSPLN-SLYFRLAKHGDIFIQHSLDRDNDPILCADSGFPDTCSTTHVVWLGSTTVISLRILINDLNDNKPFWSAIPTVSIAENSPINIEVDLPLAIDKDTNTNGIERYELLTKNVVEFELKNQQSPN-GIIPKLIIKTNLDREKVSSYNLTLAAIDGSRPHHTGTVVLFIEIADQNDNSPIFEKSTYRVSIFENFTVSTYLPIHPNAIDADSGKFGEISYYFSIATPEDVKNIFSIDRISGKILVEKNIDYDSGKVL-YEFIIVAIDGGSPAFSSTASIIIEINDVNDQAPAIAITHISDETNSFLEFPENNLSNSLVTTITVSDSDTGDGGKFNCSLSLTNSFTMNFYKLLDQISIYQLITVRPFDRETESNIHTQILCQDKGNPVKYSKKLITVNISDINDNPPRFSQTKYRFQFKEENNPNSKVGEVFVTDNDIGNNSRIEYFIV---STDGAKVPFRIDNKGIINATVRIDREIHHNGFKFQIVAKDCGTPYLNDSVEVEIEIIDINDCVPIFNKTEYPFQIIENDGVKSSL---PLSIGLVDATDCDIGNNGKITFKLGEPSNKFQISEKGLLEQIDFVDRENQSFYSFTVLAIDSIPMSLRRNTGTTIVSIRVDDRNDNPPVFIQSINVSNPIKVSYEEEIGFEIHRVQTKDADVGLNAIITYKIKSNNYVNEIFVIDEKSGSITIAKRLTSSHQGEKTLHIVATDLGSPSLSSEMELKIIIDDSSPNSQPPNANRFLINNNKLIIIIVVIATVLVCAILISVICLMVNCKFSSHRNGVTMTYEEDGTKPIRGFPYQGYPKYDLSNGKFTDVNESLLNLSSNFYLINNQQSTNC 886
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000063589.1 (SMESG000063589.1) HSP 1 Score: 345.895 bits (886), Expect = 5.016e-103 Identity = 266/867 (30.68%), Postives = 429/867 (49.48%), Query Frame = 2
Query: 65 FIFSMSIIDR-DSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNM-----LHVHSYFRLSSSGIISVARQLDCDNDSNLC-DKTLEY--CMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRX-XXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKD--------ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS------DPRTTNQMFPPFLIESNGNLLVNQHLDRL--LDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFH--RNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELE----NVDKKAVSM 2569
FIF +S ++ + +++S+ E P+N V +L+ + S F L + YF ++ + + V +D D + +LC + T E+ T + + ++ + I I D+NDN P W PI + I EN G ++ A D D ++ K SS F L P P+L + + +D E L + D P +G I+I+ILD NDN P F + +++ EN+ L L +N++AVD DSG FG + Y S S+ + F+IN+ +G I +I+++DYD G +L ++F+VVA D G P LSS V I I DVND+ P I +N ++I ENN++ + + +S D D + NC L F L+F++N++ + IY+L+A FDRE + T+ C D G P +TSS+ + +I+ DVNDN P F S+ + E + T++ K+RA D D G N +L Y+IS DPR P + NG ++ Q LDR L G F +I + D G S + I+L DIN+C P F+ ++ F + ED + + +P+ +G I V+D D G N + I + F+I N +++ +DRE ++ Y LT++A+DG D +IRHT + V I + D+NDN+P F+ +N +P VS E L D D G NA V I G I F I+ + + ++S+ + + ++ +D G P SS++ I+I + D+ + + N + I+I I V I+ + ITI+ + R C L ++D++A +M
Sbjct: 12 FIFKLSSMNSINKLSVSIYENVPLNVSVVNLRPEIE---KSQKDFKYELLMGLSQNKYFYVNKNYDLIVLTNIDRDRNPDLCKEMTTEFLCVWTGVIMFEGYNVIISLRIEIKDVNDNIPFWNHPILIEIMENNPPGKTIDLTQAQDDDSPPNNVQRYELMSNKYSSIFRLTKEP-GPSGIIPRLTILTVLDHEKYKEFSLTLNAFDGAYPYHSGSVNISIKILDQNDNAPKFEKSHFSLTIPENYPLFKPLMLNLTAVDDDSGQFGSVIYYISESSPPDSLKKFSINN-HGIITVIRNIDYDIGEKL-FTFIVVAKDQGNPPLSSLAMVKITIKDVNDQPPTILINSYSTSGSKNNPSVLSIVENNSIGQAVARISATDSDSFESDFCNCTLTHFSDFQLVFERNVAKMTIYRLIANKVFDRETRSIIKVTVICSDTGYPPMTSSETLRIIVEDVNDNNPIFDKNVYSYVVAEENAPNTIIAKLRATDDDAGKNGKLTYNISPNSKFRDPR------PAIKVNENGEIIAVQPLDRESNLQGYKFQIIAI--DQGDNPRSGTTIVVIHLNDINDCKPKFSDDSYFFQLEEDSG--ISSIFRPKIVGSIKVTDADIGKNGISSFEILPKNSPFKIDENKYIKTTRFIDREHRKNYMLTVLAVDGLADSEIRHTTSTVVNITVTDVNDNAPQFYIPKNLSIPINVSLYEEPGFVFTNLQATDSDEGENARVTYHISGGNIFGLFEIESQTGRLSVRDHIQSKLKVPFTVTILARDHGTPSLSSTVVIRILLTDTPAIGTEINKLNNRTASSTQTNQILIMIIVTITCVICIGLITIICLMARGIVFRQRYCKTLSEKQMSMDERASTM 862
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000063589.1 (SMESG000063589.1) HSP 1 Score: 341.273 bits (874), Expect = 1.510e-101 Identity = 262/856 (30.61%), Postives = 422/856 (49.30%), Query Frame = 2
Query: 95 DSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNM-----LHVHSYFRLSSSGIISVARQLDCDNDSNLC-DKTLEY--CMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWPKPIELSISENAFIGTLFNIPPAVDLDRX-XXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLKSSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISLNKSLKD--------ITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIGHKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHIS------DPRTTNQMFPPFLIESNGNLLVNQHLDRL--LDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNINKFQISHNGMLQSVAVLDREEKEEYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFH--RNFPLPTKVSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSIEIQITIDDSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELE----NVDKKAVSM 2569
+ +++S+ E P+N V +L+ + S F L + YF ++ + + V +D D + +LC + T E+ T + + ++ + I I D+NDN P W PI + I EN G ++ A D D ++ K SS F L P P+L + + +D E L + D P +G I+I+ILD NDN P F + +++ EN+ L L +N++AVD DSG FG + Y S S+ + F+IN+ +G I +I+++DYD G +L ++F+VVA D G P LSS V I I DVND+ P I +N ++I ENN++ + + +S D D + NC L F L+F++N++ + IY+L+A FDRE + T+ C D G P +TSS+ + +I+ DVNDN P F S+ + E + T++ K+RA D D G N +L Y+IS DPR P + NG ++ Q LDR L G F +I + D G S + I+L DIN+C P F+ ++ F + ED + + +P+ +G I V+D D G N + I + F+I N +++ +DRE ++ Y LT++A+DG D +IRHT + V I + D+NDN+P F+ +N +P VS E L D D G NA V I G I F I+ + + ++S+ + + ++ +D G P SS++ I+I + D+ + + N + I+I I V I+ + ITI+ + R C L ++D++A +M
Sbjct: 5 NKLSVSIYENVPLNVSVVNLRPEIE---KSQKDFKYELLMGLSQNKYFYVNKNYDLIVLTNIDRDRNPDLCKEMTTEFLCVWTGVIMFEGYNVIISLRIEIKDVNDNIPFWNHPILIEIMENNPPGKTIDLTQAQDDDSPPNNVQRYELMSNKYSSIFRLTKEP-GPSGIIPRLTILTVLDHEKYKEFSLTLNAFDGAYPYHSGSVNISIKILDQNDNAPKFEKSHFSLTIPENYPLFKPLMLNLTAVDDDSGQFGSVIYYISESSPPDSLKKFSINN-HGIITVIRNIDYDIGEKL-FTFIVVAKDQGNPPLSSLAMVKITIKDVNDQPPTILINSYSTSGSKNNPSVLSIVENNSIGQAVARISATDSDSFESDFCNCTLTHFSDFQLVFERNVAKMTIYRLIANKVFDRETRSIIKVTVICSDTGYPPMTSSETLRIIVEDVNDNNPIFDKNVYSYVVAEENAPNTIIAKLRATDDDAGKNGKLTYNISPNSKFRDPR------PAIKVNENGEIIAVQPLDRESNLQGYKFQIIAI--DQGDNPRSGTTIVVIHLNDINDCKPKFSDDSYFFQLEEDSG--ISSIFRPKIVGSIKVTDADIGKNGISSFEILPKNSPFKIDENKYIKTTRFIDREHRKNYMLTVLAVDGLADSEIRHTTSTVVNITVTDVNDNAPQFYIPKNLSIPINVSLYEEPGFVFTNLQATDSDEGENARVTYHISGGNIFGLFEIESQTGRLSVRDHIQSKLKVPFTVTILARDHGTPSLSSTVVIRILLTDTPAIGTEINKLNNRTASSTQTNQILIMIIVTITCVICIGLITIICLMARGIVFRQRYCKTLSEKQMSMDERASTM 844
BLAST of Protocadherin vs. Planmine SMEST
Match: SMESG000022902.1 (SMESG000022902.1) HSP 1 Score: 307.375 bits (786), Expect = 8.750e-90 Identity = 253/865 (29.25%), Postives = 418/865 (48.32%), Query Frame = 2
Query: 71 FSMSII-DRDSITLSVEERFPVNYFVTDLKNILAIPLNSSTRFNMLHVHSYFRLSSSGIISVARQLDCDNDSNLCDKTLEY---CMTKLFXXXXXXXXXXXXXXXXDLNDNAPHWP-KPIELSISENAFIGTLFNIPPAVDLDRXXXXXXXXXXXXXXSSYFDLAFLPTDDEHQFPKLKLK--SSIDRETNDRIELVILLTDSGSPPLTGEGIITIQILDVNDNYPTFSTHKYIISLRENFQLNSLLPINVSAVDCDSGNFGKLSYKHSVSNTDSVKRHFAINSTNGEIRLIKSLDYDSGNELSYSFVVVAHDHGQPALSSSTTVIINIVDVNDELPIISL----NKSLKDITIFENNNLNEPIVDVSVHDLDQGINGQFNCFLIG--HKGFDLLFKQNLSDLIIYQLMAKHKFDREKEAFAYTTITCCDYGIPSLTSSQLITVIIVDVNDNLPTFSMPATSFSILEHSPIGTVVTKVRALDKDEGLNSQLIYHISDPRTTNQMFPPFLIESNGNLLVNQHLDRLLDGEIFSVIVVVSDHGRPALSNQIEITINLIDINNCPPVFNQSTFHFTVPEDPSDHLPLVPKPRNIGYIAVSDCDKGVNAQLTLAIKDNIN-KFQI-SHNGMLQSVAVLDREEKE-EYKLTLIAIDGTPDVQIRHTVTGSVVIFLNDLNDNSPIFHRNFPLPTK----VSYKEYVRHELIALFVEDKDSGANAVVDLSIKPGIIAPYFSIDRDRQSVKLNRKLKSEHQGIHKLIVIGKDRGRPPKSSSI-EIQITID-----------DSQPLSPKNMVHFNESKEKINKEMIVITIAVIISVLALGSFITIVIIKCRKKAKPPLICYELENVDKKAVSM 2569
+S+SI+ ++ I L ++E + + DL+ L + +F+ L + YF + + ++ LD D D LC + E+ C + + N ++ I IND+NDN P W I L ISEN G P A D D Q S ++ + + + P+L L S +DRE N + ++ D G L+G ++I+ILD NDN P F + Y + + E+ + LP+ + A D D+GNFGK++YK S+S V F+I+ I KSL++ S + Y F +VA D G P ++ T++ + IVD N P I + + + K+I + EN+ +N + +++D D GIN +FNC L G K F+L + L L IY L K FDRE E+ I+C D G+P LT SQ I + + D+ND+ P F P E + ++V + A D D+G N++L Y I P Q PF I+S G L LDR + + ++ V+ D+G P+ S + I L D+N+CPP FN+ + F + ED + + +++G + D D NA + + IN F+I S +G + + ++DRE + +A+D ++ R T T + + + D+NDN P F FP T+ +SY H + + D+D+G NA + I G FS++ D + LN LK ++G L + D G+ +++ +I+I I D +P + +HF+ + +I++ + +IS + +G+ I ++ R+ A E+E D K +++
Sbjct: 15 YSISILQNQRQIFLDIDENIEIGTRIIDLQTKLLSNEEKNIKFS-LTSNPYFHIRENSVLYTKSFLDRDKDRELCHNS-EFPANCQWSRLLTLGNGGYYILKITINDVNDNPPKWEINHIHLKISENTQPGYKLEFPLATDDDFGINGIQYYTIFPISSVFY---VSDSGNGERSPRLVLSKGSKLDRELNSWHNMTLVAYDGGINKLSGTVPVSIEILDENDNGPVFQSSFYNVLIDEDIMPGTTLPLRIHAYDLDAGNFGKITYKFSLSTPQHVLEIFSISPNTANIITSKSLNFKSRRKF-YDFEIVAQDGGIPPKTAQTSIKVEIVDKNTHAPEIKVTPMPDPTSKNIIVPENSAINRIVASFTINDKDSGINSKFNCSLTGLNSKDFNLKHSKKLGKLEIYVLETKRSFDRELESLLTVCISCQDQGVPQLTGSQDILIEVEDINDHSPVFQHPEYRLRTTEGNAPNSLVYHILATDMDKGDNARLRYKIIWPDIETQSL-PFKIDSEGRLFAKYVLDREANPQGYTFQVMAFDYGDPSKSASTIVKIELEDLNDCPPKFNRDHYQFQIKEDYGN----IHIRQHVGDVYAEDLDLQENAIVFYRLSQEINVPFEIDSKSGSIYTSKLIDRESVSVPFSFLCMAVDNPFNLLYRKTATVEITVTIIDVNDNKPQFI--FPNETQQDINLSYYARKEHFVGKVIANDQDAGINAKIKYIITQGNALKLFSLNNDTGVINLNTDLKPSNKGYELLTIKAIDSGQFQIHTAVCQIRIKISNFQLITKPEYKDQKPSNESGFLHFDWWEPNKMIIIIILLVTALISCILIGA---ICVMAKRRNA-------EVEKNDIKMINL 856 The following BLAST results are available for this feature:
BLAST of Protocadherin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protocadherin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protocadherin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protocadherin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protocadherin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Protocadherin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protocadherin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protocadherin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024873 ID=SMED30024873|Name=Protocadherin|organism=Schmidtea mediterranea sexual|type=transcript|length=2961bpback to top protein sequence of SMED30024873-orf-1 >SMED30024873-orf-1 ID=SMED30024873-orf-1|Name=SMED30024873-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=965bp MLCLYLLLTSQFIFSMSIIDRDSITLSVEERFPVNYFVTDLKNILAIPLNback to top Annotated Terms
The following terms have been associated with this transcript:
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