Papilin

Overview
NamePapilin
Smed IDSMED30024859
Length (bp)623
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Papilin (SMED30024859) t-SNE clustered cells

Violin plots show distribution of expression levels for Papilin (SMED30024859) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Papilin (SMED30024859) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Papilin (SMED30024859) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30024859

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30024859 SmedASXL_049784SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
neoblastSMED30024859 dd_Smed_v4_1349_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30024859 dd_Smed_v4_1349_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
prepharyngeal regionSMED30024859 dd_Smed_v6_1349_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30024859 OX_Smed_1.0.09448ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Papilin vs. Ensembl Human
Match: APP (amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620])

HSP 1 Score: 63.1586 bits (152), Expect = 4.071e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  241 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 285
[Close]
BLAST of Papilin vs. Ensembl Human
Match: APP (amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620])

HSP 1 Score: 63.1586 bits (152), Expect = 4.111e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  292 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 336
[Close]
BLAST of Papilin vs. Ensembl Human
Match: APP (amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620])

HSP 1 Score: 63.1586 bits (152), Expect = 4.116e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. Ensembl Human
Match: APP (amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620])

HSP 1 Score: 63.1586 bits (152), Expect = 4.118e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. Ensembl Human
Match: APP (amyloid beta precursor protein [Source:HGNC Symbol;Acc:HGNC:620])

HSP 1 Score: 63.1586 bits (152), Expect = 4.138e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 60.077 bits (144), Expect = 2.015e-10
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 2 
Query:   89 CLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            C++      +  C   +  G C+   +++ FD   +AC+ FTY GCGGN NNF T ++C   C+N G
Sbjct:  854 CVMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVNRG 920

HSP 2 Score: 57.7658 bits (138), Expect = 1.272e-9
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL    +G C  +  +++FD+ +  C  FTYTGC GNGNNF + E+C A C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 3 Score: 57.3806 bits (137), Expect = 1.385e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C+  V  G+C E   +YY+D    +C+ F Y+GC GN NNF + EDC   C+
Sbjct: 2741 LCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCV 2793

HSP 4 Score: 50.8322 bits (120), Expect = 2.394e-7
Identity = 18/44 (40.91%), Postives = 27/44 (61.36%), Query Frame = 2 
Query:  146 GTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            G C     +Y+++     C+ FTY+GCGGNGNN+++ E C   C
Sbjct:  430 GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 5 Score: 49.6766 bits (117), Expect = 6.847e-7
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            T C L    G C +   ++YF+   + CK F + GC GN NNF+  EDC +AC
Sbjct:  537 TRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 48.9062 bits (115), Expect = 1.141e-6
Identity = 20/51 (39.22%), Postives = 27/51 (52.94%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL  V  G C     ++YF+  +  C PF Y GC GN N+F T ++C   C
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1133
[Close]
BLAST of Papilin vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 60.077 bits (144), Expect = 2.034e-10
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 2 
Query:   89 CLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            C++      +  C   +  G C+   +++ FD   +AC+ FTY GCGGN NNF T ++C   C+N G
Sbjct:  845 CVMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVNRG 911

HSP 2 Score: 57.7658 bits (138), Expect = 1.272e-9
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL    +G C  +  +++FD+ +  C  FTYTGC GNGNNF + E+C A C
Sbjct:  728 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 778

HSP 3 Score: 57.3806 bits (137), Expect = 1.385e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C+  V  G+C E   +YY+D    +C+ F Y+GC GN NNF + EDC   C+
Sbjct: 2732 LCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCV 2784

HSP 4 Score: 50.8322 bits (120), Expect = 2.394e-7
Identity = 18/44 (40.91%), Postives = 27/44 (61.36%), Query Frame = 2 
Query:  146 GTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            G C     +Y+++     C+ FTY+GCGGNGNN+++ E C   C
Sbjct:  430 GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 5 Score: 49.6766 bits (117), Expect = 6.847e-7
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            T C L    G C +   ++YF+   + CK F + GC GN NNF+  EDC +AC
Sbjct:  537 TRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 48.9062 bits (115), Expect = 1.141e-6
Identity = 20/51 (39.22%), Postives = 27/51 (52.94%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL  V  G C     ++YF+  +  C PF Y GC GN N+F T ++C   C
Sbjct: 1074 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1124
[Close]
BLAST of Papilin vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 59.6918 bits (143), Expect = 2.692e-10
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 2 
Query:   89 CLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            C++      +  C   +  G C+   +++ FD   +AC+ FTY GCGGN NNF T ++C   C+N G
Sbjct:  725 CVMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVNRG 791

HSP 2 Score: 57.3806 bits (137), Expect = 1.606e-9
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL    +G C  +  +++FD+ +  C  FTYTGC GNGNNF + E+C A C
Sbjct:  608 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 658

HSP 3 Score: 56.9954 bits (136), Expect = 1.798e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C+  V  G+C E   +YY+D    +C+ F Y+GC GN NNF + EDC   C+
Sbjct: 2612 LCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCV 2664

HSP 4 Score: 50.447 bits (119), Expect = 2.961e-7
Identity = 18/44 (40.91%), Postives = 27/44 (61.36%), Query Frame = 2 
Query:  146 GTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            G C     +Y+++     C+ FTY+GCGGNGNN+++ E C   C
Sbjct:  301 GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 344

HSP 5 Score: 49.2914 bits (116), Expect = 8.622e-7
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            T C L    G C +   ++YF+   + CK F + GC GN NNF+  EDC +AC
Sbjct:  408 TRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 460

HSP 6 Score: 48.521 bits (114), Expect = 1.384e-6
Identity = 20/51 (39.22%), Postives = 27/51 (52.94%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL  V  G C     ++YF+  +  C PF Y GC GN N+F T ++C   C
Sbjct:  954 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1004
[Close]
BLAST of Papilin vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667209:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3h.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 58.5362 bits (140), Expect = 6.284e-10
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 2 
Query:   89 CLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            C++      +  C   +  G C+   +++ FD   +AC+ FTY GCGGN NNF T ++C   C+N G
Sbjct:  633 CVMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVNRG 699

HSP 2 Score: 56.225 bits (134), Expect = 3.848e-9
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL    +G C  +  +++FD+ +  C  FTYTGC GNGNNF + E+C A C
Sbjct:  516 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 566

HSP 3 Score: 56.225 bits (134), Expect = 4.226e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C+  V  G+C E   +YY+D    +C+ F Y+GC GN NNF + EDC   C+
Sbjct: 2139 LCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCV 2191

HSP 4 Score: 49.6766 bits (117), Expect = 6.657e-7
Identity = 18/44 (40.91%), Postives = 27/44 (61.36%), Query Frame = 2 
Query:  146 GTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            G C     +Y+++     C+ FTY+GCGGNGNN+++ E C   C
Sbjct:  209 GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 252

HSP 5 Score: 48.1358 bits (113), Expect = 1.748e-6
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            T C L    G C +   ++YF+   + CK F + GC GN NNF+  EDC +AC
Sbjct:  316 TRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 368

HSP 6 Score: 47.7506 bits (112), Expect = 2.830e-6
Identity = 20/51 (39.22%), Postives = 27/51 (52.94%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL  V  G C     ++YF+  +  C PF Y GC GN N+F T ++C   C
Sbjct:  862 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 912
[Close]
BLAST of Papilin vs. Ensembl Celegans
Match: mlt-11 (pep chromosome:WBcel235:V:20667211:20678513:1 gene:WBGene00012186.1 transcript:W01F3.3e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:mlt-11)

HSP 1 Score: 58.151 bits (139), Expect = 8.423e-10
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 2 
Query:   89 CLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            C++      +  C   +  G C+   +++ FD   +AC+ FTY GCGGN NNF T ++C   C+N G
Sbjct:  854 CVMAMKKSPVATCEADIEVGECAGVFSRFAFDKSINACRSFTYGGCGGNANNFATLQECTNKCVNRG 920

HSP 2 Score: 55.8398 bits (133), Expect = 5.058e-9
Identity = 23/51 (45.10%), Postives = 32/51 (62.75%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL    +G C  +  +++FD+ +  C  FTYTGC GNGNNF + E+C A C
Sbjct:  737 CLHPRDSGNCRGQFVRWFFDDEKKNCDVFTYTGCQGNGNNFASKEECMAIC 787

HSP 3 Score: 55.8398 bits (133), Expect = 5.555e-9
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C+  V  G+C E   +YY+D    +C+ F Y+GC GN NNF + EDC   C+
Sbjct: 2215 LCIQPVVKGSCQEAHLRYYYDRVTDSCRLFEYSGCDGNANNFGSLEDCQRLCV 2267

HSP 4 Score: 49.2914 bits (116), Expect = 8.103e-7
Identity = 18/44 (40.91%), Postives = 27/44 (61.36%), Query Frame = 2 
Query:  146 GTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            G C     +Y+++     C+ FTY+GCGGNGNN+++ E C   C
Sbjct:  430 GPCHGSFQRYFYNEDSQKCEQFTYSGCGGNGNNYESREACEDRC 473

HSP 5 Score: 48.1358 bits (113), Expect = 2.187e-6
Identity = 22/53 (41.51%), Postives = 30/53 (56.60%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            T C L    G C +   ++YF+   + CK F + GC GN NNF+  EDC +AC
Sbjct:  537 TRCSLPKERGPCDKYELRFYFNADLNECKYFFWGGCEGNQNNFERVEDCESAC 589

HSP 6 Score: 47.3654 bits (111), Expect = 3.572e-6
Identity = 20/51 (39.22%), Postives = 27/51 (52.94%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL  V  G C     ++YF+  +  C PF Y GC GN N+F T ++C   C
Sbjct: 1083 CLQPVEPGPCKNFADRWYFNVDDGTCHPFKYGGCAGNRNHFFTQKECEVHC 1133
[Close]
BLAST of Papilin vs. Ensembl Fly
Match: Ppn (gene:FBgn0003137 transcript:FBtr0301838)

HSP 1 Score: 58.151 bits (139), Expect = 1.145e-9
Identity = 26/51 (50.98%), Postives = 31/51 (60.78%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            C L   TG CSE++ K++F   E  C PF Y+GCGGN NNF T E C   C
Sbjct: 1790 CALPKQTGDCSEKLAKWHFSESEKRCVPFYYSGCGGNKNNFPTLESCEDHC 1840

HSP 2 Score: 56.9954 bits (136), Expect = 2.743e-9
Identity = 24/62 (38.71%), Postives = 35/62 (56.45%), Query Frame = 2 
Query:   92 LIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +++    T ++C      G C  R T +++D+   AC  FTYTGCGGNGN F+T + C   C
Sbjct: 2183 VVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQC 2244

HSP 3 Score: 53.5286 bits (127), Expect = 4.224e-8
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            IC +    G C+  VT +Y+D  + AC+ F Y GCGGN N F T E C A C
Sbjct: 1848 ICEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARC 1899

HSP 4 Score: 51.6026 bits (122), Expect = 1.604e-7
Identity = 26/69 (37.68%), Postives = 34/69 (49.28%), Query Frame = 2 
Query:  116 LTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKK 322
            L  C   V +G C+    ++Y+DN    C+PFTY GC GN NN+ T   C   C   G     C L K+
Sbjct: 1727 LPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPGVLKDRCALPKQ 1795

HSP 5 Score: 50.8322 bits (120), Expect = 2.885e-7
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            + C L+   G C   VT++++++ E  C  F YTGCGGN NN+ T E+C   C
Sbjct: 2069 SKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNEC 2121

HSP 6 Score: 50.0618 bits (118), Expect = 5.282e-7
Identity = 23/54 (42.59%), Postives = 31/54 (57.41%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C    + G CS  V K++FD    AC+ F Y  CGGNGN F+T  DC   C++
Sbjct: 1921 VCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCLS 1974

HSP 7 Score: 47.7506 bits (112), Expect = 3.319e-6
Identity = 22/52 (42.31%), Postives = 28/52 (53.85%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +CLL  S G C+    K+YFD   + C+ F Y GC G  N FD+ E C   C
Sbjct: 1670 VCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTC 1721

HSP 8 Score: 47.3654 bits (111), Expect = 4.674e-6
Identity = 23/54 (42.59%), Postives = 28/54 (51.85%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            T C L    G CS+   ++YFD     C  F +TGC GN NNF +  DC   CI
Sbjct: 2126 TTCALPPVRGRCSDLSRRWYFDERSGECHEFEFTGCRGNRNNFVSQSDCLNFCI 2179
[Close]
BLAST of Papilin vs. Ensembl Fly
Match: Ppn (gene:FBgn0003137 transcript:FBtr0301837)

HSP 1 Score: 58.151 bits (139), Expect = 1.180e-9
Identity = 26/51 (50.98%), Postives = 31/51 (60.78%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            C L   TG CSE++ K++F   E  C PF Y+GCGGN NNF T E C   C
Sbjct: 1790 CALPKQTGDCSEKLAKWHFSESEKRCVPFYYSGCGGNKNNFPTLESCEDHC 1840

HSP 2 Score: 57.7658 bits (138), Expect = 1.261e-9
Identity = 24/62 (38.71%), Postives = 35/62 (56.45%), Query Frame = 2 
Query:   92 LIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +++    T ++C      G C  R T +++D+   AC  FTYTGCGGNGN F+T + C   C
Sbjct: 2183 VVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQC 2244

HSP 3 Score: 57.3806 bits (137), Expect = 1.835e-9
Identity = 29/71 (40.85%), Postives = 39/71 (54.93%), Query Frame = 2 
Query:  116 LTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI-----NIGK*YLICLL 313
            + +C   V+TG C++  TKYYF+    AC+PFTY GC G GN F    +C   C+      +G    ICLL
Sbjct: 2250 VDVCNEPVTTGPCTDWQTKYYFNTASQACEPFTYGGCDGTGNRFSDLFECQTVCLAGREPRVGSAKEICLL 2320

HSP 4 Score: 53.5286 bits (127), Expect = 4.435e-8
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            IC +    G C+  VT +Y+D  + AC+ F Y GCGGN N F T E C A C
Sbjct: 1848 ICEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARC 1899

HSP 5 Score: 52.373 bits (124), Expect = 9.016e-8
Identity = 26/70 (37.14%), Postives = 34/70 (48.57%), Query Frame = 2 
Query:  116 LTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKKI 325
            L  C   V +G C+    ++Y+DN    C+PFTY GC GN NN+ T   C   C   G     C L K+ 
Sbjct: 1727 LPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPGVLKDRCALPKQT 1796

HSP 6 Score: 50.8322 bits (120), Expect = 3.000e-7
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            + C L+   G C   VT++++++ E  C  F YTGCGGN NN+ T E+C   C
Sbjct: 2069 SKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNEC 2121

HSP 7 Score: 50.0618 bits (118), Expect = 5.917e-7
Identity = 23/54 (42.59%), Postives = 31/54 (57.41%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C    + G CS  V K++FD    AC+ F Y  CGGNGN F+T  DC   C++
Sbjct: 1921 VCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCLS 1974

HSP 8 Score: 47.3654 bits (111), Expect = 4.860e-6
Identity = 22/53 (41.51%), Postives = 28/53 (52.83%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +CLL  S G C+    K+YFD   + C+ F Y GC G  N FD+ E C   C 
Sbjct: 1670 VCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTCA 1722

HSP 9 Score: 46.9802 bits (110), Expect = 6.971e-6
Identity = 23/54 (42.59%), Postives = 28/54 (51.85%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            T C L    G CS+   ++YFD     C  F +TGC GN NNF +  DC   CI
Sbjct: 2126 TTCALPPVRGRCSDLSRRWYFDERSGECHEFEFTGCRGNRNNFVSQSDCLNFCI 2179
[Close]
BLAST of Papilin vs. Ensembl Fly
Match: Ppn (gene:FBgn0003137 transcript:FBtr0301839)

HSP 1 Score: 58.151 bits (139), Expect = 1.190e-9
Identity = 24/62 (38.71%), Postives = 35/62 (56.45%), Query Frame = 2 
Query:   92 LIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +++    T ++C      G C  R T +++D+   AC  FTYTGCGGNGN F+T + C   C
Sbjct: 2126 VVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQC 2187

HSP 2 Score: 57.3806 bits (137), Expect = 1.717e-9
Identity = 29/71 (40.85%), Postives = 39/71 (54.93%), Query Frame = 2 
Query:  116 LTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI-----NIGK*YLICLL 313
            + +C   V+TG C++  TKYYF+    AC+PFTY GC G GN F    +C   C+      +G    ICLL
Sbjct: 2193 VDVCNEPVTTGPCTDWQTKYYFNTASQACEPFTYGGCDGTGNRFSDLFECQTVCLAGREPRVGSAKEICLL 2263

HSP 3 Score: 53.5286 bits (127), Expect = 4.349e-8
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            IC +    G C+  VT +Y+D  + AC+ F Y GCGGN N F T E C A C
Sbjct: 1791 ICEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARC 1842

HSP 4 Score: 50.8322 bits (120), Expect = 2.835e-7
Identity = 22/53 (41.51%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            + C L+   G C   VT++++++ E  C  F YTGCGGN NN+ T E+C   C
Sbjct: 2012 SKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNEC 2064

HSP 5 Score: 50.447 bits (119), Expect = 4.642e-7
Identity = 26/72 (36.11%), Postives = 36/72 (50.00%), Query Frame = 2 
Query:  116 LTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG--K*YLICLLFKKI 325
            L  C   V +G C+    ++Y+DN    C+PFTY GC GN NN+ T   C   C   G  K   IC +  ++
Sbjct: 1727 LPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPGVLKAKDICEIPAEV 1798

HSP 6 Score: 50.0618 bits (118), Expect = 5.644e-7
Identity = 23/54 (42.59%), Postives = 31/54 (57.41%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C    + G CS  V K++FD    AC+ F Y  CGGNGN F+T  DC   C++
Sbjct: 1864 VCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCLS 1917

HSP 7 Score: 47.3654 bits (111), Expect = 4.723e-6
Identity = 22/53 (41.51%), Postives = 28/53 (52.83%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +CLL  S G C+    K+YFD   + C+ F Y GC G  N FD+ E C   C 
Sbjct: 1670 VCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTCA 1722

HSP 8 Score: 46.9802 bits (110), Expect = 6.838e-6
Identity = 23/54 (42.59%), Postives = 28/54 (51.85%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            T C L    G CS+   ++YFD     C  F +TGC GN NNF +  DC   CI
Sbjct: 2069 TTCALPPVRGRCSDLSRRWYFDERSGECHEFEFTGCRGNRNNFVSQSDCLNFCI 2122
[Close]
BLAST of Papilin vs. Ensembl Fly
Match: CG42828 (gene:FBgn0262010 transcript:FBtr0303835)

HSP 1 Score: 50.447 bits (119), Expect = 2.089e-8
Identity = 30/84 (35.71%), Postives = 37/84 (44.05%), Query Frame = 2 
Query:   56 MKLLISVLLFACLIQAMCCTL-------TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINI 286
            MKLL     F CL+  +  T+         C L    G C      + F N E  C PF ++ CGGN N F T E+C  AC  I
Sbjct:    1 MKLLTQ---FLCLLAVLLSTVESAEKRKAFCYLPYEFGKCGGHRIMWAFSNKEQECVPFVFSNCGGNENRFYTKENCEKACATI 81
[Close]
BLAST of Papilin vs. Ensembl Fly
Match: CG13748 (gene:FBgn0033355 transcript:FBtr0088656)

HSP 1 Score: 48.1358 bits (113), Expect = 2.875e-7
Identity = 18/53 (33.96%), Postives = 28/53 (52.83%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
              CL+    G C   + ++ +D  +  C  F + GC GN NNF +Y+DC + C
Sbjct:   58 QFCLMPARKGVCRALIPRWRYDPEQKKCVEFKFGGCDGNENNFASYKDCMSTC 110
[Close]
BLAST of Papilin vs. Ensembl Zebrafish
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 66.2402 bits (160), Expect = 6.891e-13
Identity = 34/91 (37.36%), Postives = 55/91 (60.44%), Query Frame = 2 
Query:   62 LLISVLLFACLIQ-AMCCTLT---ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKK 322
            LL ++LLF  +++ A+  TL    +CLL +  GTC++ + ++Y++     C+ F+Y+GCGGN NNF ++ +C   C  I K   IC   KK
Sbjct:    5 LLGALLLFISVLESAVGLTLQPKEVCLLQIEEGTCNDDIQRFYYNTISQQCEEFSYSGCGGNQNNFRSFVECQKTCFRIPKIPQICRFQKK 95

HSP 2 Score: 50.8322 bits (120), Expect = 1.760e-7
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            ICL ++  G CS  + +YY+++    C+ F YTGCGG+ NNF + + C   C
Sbjct:  149 ICLDNLDKGRCSASIPRYYYNSATKTCEEFMYTGCGGSNNNFISKQSCVDVC 200

HSP 3 Score: 49.2914 bits (116), Expect = 5.909e-7
Identity = 24/64 (37.50%), Postives = 31/64 (48.44%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICL 310
             IC      G C    ++Y+F+     C+PFTY GC GN NNF   E+C   C       +ICL
Sbjct:   88 QICRFQKKEGPCRGLFSRYFFNMTSMQCEPFTYGGCQGNENNFRNPEECIEYCKPPKTIPVICL 151
[Close]
BLAST of Papilin vs. Ensembl Zebrafish
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 66.2402 bits (160), Expect = 6.891e-13
Identity = 34/91 (37.36%), Postives = 55/91 (60.44%), Query Frame = 2 
Query:   62 LLISVLLFACLIQ-AMCCTLT---ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKK 322
            LL ++LLF  +++ A+  TL    +CLL +  GTC++ + ++Y++     C+ F+Y+GCGGN NNF ++ +C   C  I K   IC   KK
Sbjct:    5 LLGALLLFISVLESAVGLTLQPKEVCLLQIEEGTCNDDIQRFYYNTISQQCEEFSYSGCGGNQNNFRSFVECQKTCFRIPKIPQICRFQKK 95

HSP 2 Score: 50.8322 bits (120), Expect = 1.760e-7
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            ICL ++  G CS  + +YY+++    C+ F YTGCGG+ NNF + + C   C
Sbjct:  149 ICLDNLDKGRCSASIPRYYYNSATKTCEEFMYTGCGGSNNNFISKQSCVDVC 200

HSP 3 Score: 49.2914 bits (116), Expect = 5.909e-7
Identity = 24/64 (37.50%), Postives = 31/64 (48.44%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICL 310
             IC      G C    ++Y+F+     C+PFTY GC GN NNF   E+C   C       +ICL
Sbjct:   88 QICRFQKKEGPCRGLFSRYFFNMTSMQCEPFTYGGCQGNENNFRNPEECIEYCKPPKTIPVICL 151
[Close]
BLAST of Papilin vs. Ensembl Zebrafish
Match: appa (amyloid beta (A4) precursor protein a [Source:ZFIN;Acc:ZDB-GENE-000616-13])

HSP 1 Score: 59.3066 bits (142), Expect = 4.424e-10
Identity = 22/51 (43.14%), Postives = 30/51 (58.82%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            C  S  TG C   ++++Y+   E  C PF Y GCGGN NNF++ E C + C
Sbjct:  293 CFASAETGPCRAMLSRWYYVREERRCAPFIYGGCGGNRNNFESEEYCLSVC 343
[Close]
BLAST of Papilin vs. Ensembl Zebrafish
Match: col7a1 (collagen, type VII, alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030131-2427])

HSP 1 Score: 58.9214 bits (141), Expect = 7.070e-10
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C+L +  G CS    ++YF++   AC+PF Y+GCGGN N +   E+C   C+
Sbjct: 3040 CILPMEEGDCSRYTLRWYFNSQVDACRPFIYSGCGGNANRYLQKEECEKLCL 3091
[Close]
BLAST of Papilin vs. Ensembl Zebrafish
Match: col7a1 (collagen, type VII, alpha 1 [Source:ZFIN;Acc:ZDB-GENE-030131-2427])

HSP 1 Score: 58.9214 bits (141), Expect = 7.070e-10
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C+L +  G CS    ++YF++   AC+PF Y+GCGGN N +   E+C   C+
Sbjct: 3040 CILPMEEGDCSRYTLRWYFNSQVDACRPFIYSGCGGNANRYLQKEECEKLCL 3091
[Close]
BLAST of Papilin vs. Ensembl Xenopus
Match: ENSXETT00000014315.1 (collagen type VI alpha 5 chain [Source:NCBI gene;Acc:100486063])

HSP 1 Score: 62.7734 bits (151), Expect = 4.906e-11
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C +    G C++ + K+ ++ G+ AC  F Y GCGGNGN FDT E C A C++
Sbjct: 2646 VCTMKQEEGKCADYILKWSYNQGKKACVQFWYGGCGGNGNRFDTQEQCEATCMS 2699
[Close]
BLAST of Papilin vs. Ensembl Xenopus
Match: ENSXETT00000014204.1 (collagen type VI alpha 5 chain [Source:NCBI gene;Acc:100486063])

HSP 1 Score: 62.7734 bits (151), Expect = 4.907e-11
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C +    G C++ + K+ ++ G+ AC  F Y GCGGNGN FDT E C A C++
Sbjct: 2659 VCTMKQEEGKCADYILKWSYNQGKKACVQFWYGGCGGNGNRFDTQEQCEATCMS 2712
[Close]
BLAST of Papilin vs. Ensembl Xenopus
Match: ENSXETT00000014273.1 (collagen type VI alpha 5 chain [Source:NCBI gene;Acc:100486063])

HSP 1 Score: 62.7734 bits (151), Expect = 4.913e-11
Identity = 23/54 (42.59%), Postives = 34/54 (62.96%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            +C +    G C++ + K+ ++ G+ AC  F Y GCGGNGN FDT E C A C++
Sbjct: 2718 VCTMKQEEGKCADYILKWSYNQGKKACVQFWYGGCGGNGNRFDTQEQCEATCMS 2771
[Close]
BLAST of Papilin vs. Ensembl Xenopus
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:548483])

HSP 1 Score: 56.9954 bits (136), Expect = 1.716e-9
Identity = 29/84 (34.52%), Postives = 37/84 (44.05%), Query Frame = 2 
Query:   62 LLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLL 313
            L+ + LL       M    T+CLL    G C   +  YY+D     C+ F Y GC GN N F + EDC   C  I K    C +
Sbjct:    8 LMAASLLIQVFGSPMQGNTTVCLLPPDEGPCKALIPHYYYDRYTQTCQEFLYGGCDGNSNKFLSMEDCEKFCWKIKKVPKACRM 91

HSP 2 Score: 55.0694 bits (131), Expect = 6.625e-9
Identity = 26/53 (49.06%), Postives = 32/53 (60.38%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            + C      G+CS  VT+YYF+    AC+ F YTGCGGN NNF   EDC + C
Sbjct:  147 SFCYSPKDEGSCSASVTRYYFNIESKACEEFVYTGCGGNSNNFVKMEDCDSVC 199
[Close]
BLAST of Papilin vs. Ensembl Xenopus
Match: APLP2 (amyloid beta (A4) precursor-like protein 2 [Source:NCBI gene;Acc:100380132])

HSP 1 Score: 57.3806 bits (137), Expect = 3.421e-9
Identity = 22/53 (41.51%), Postives = 31/53 (58.49%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            ++C     TG C   + ++YFD G+  C  F Y GCGGN NNF++ + C A C
Sbjct:  273 SVCSQEAMTGPCRAMMPRWYFDLGQKKCVRFIYGGCGGNRNNFESEDYCMAVC 325
[Close]
BLAST of Papilin vs. Ensembl Mouse
Match: Wfdc8 (WAP four-disulfide core domain 8 [Source:MGI Symbol;Acc:MGI:2685552])

HSP 1 Score: 62.003 bits (149), Expect = 2.880e-11
Identity = 29/70 (41.43%), Postives = 41/70 (58.57%), Query Frame = 2 
Query:   83 FACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK 292
            FAC  + M      C+L    G C + +T++YFD+ +H C+ F Y+GC GN NNF T  DC  AC+ + K
Sbjct:  113 FACGRKCMDPYEEPCMLPSDKGNCQDILTRWYFDSQKHQCRAFLYSGCRGNANNFLTKTDCRNACMFVEK 182
[Close]
BLAST of Papilin vs. Ensembl Mouse
Match: Wfdc8 (WAP four-disulfide core domain 8 [Source:MGI Symbol;Acc:MGI:2685552])

HSP 1 Score: 61.6178 bits (148), Expect = 3.872e-11
Identity = 29/70 (41.43%), Postives = 41/70 (58.57%), Query Frame = 2 
Query:   83 FACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK 292
            FAC  + M      C+L    G C + +T++YFD+ +H C+ F Y+GC GN NNF T  DC  AC+ + K
Sbjct:  113 FACGRKCMDPYEEPCMLPSDKGNCQDILTRWYFDSQKHQCRAFLYSGCRGNANNFLTKTDCRNACMFVEK 182
[Close]
BLAST of Papilin vs. Ensembl Mouse
Match: App (amyloid beta (A4) precursor protein [Source:MGI Symbol;Acc:MGI:88059])

HSP 1 Score: 62.3882 bits (150), Expect = 4.639e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. Ensembl Mouse
Match: App (amyloid beta (A4) precursor protein [Source:MGI Symbol;Acc:MGI:88059])

HSP 1 Score: 62.3882 bits (150), Expect = 4.663e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. Ensembl Mouse
Match: App (amyloid beta (A4) precursor protein [Source:MGI Symbol;Acc:MGI:88059])

HSP 1 Score: 62.3882 bits (150), Expect = 4.664e-11
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCVPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. UniProt/SwissProt
Match: sp|Q7YRQ8|TFPI2_BOVIN (Tissue factor pathway inhibitor 2 OS=Bos taurus OX=9913 GN=TFPI2 PE=2 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 8.642e-11
Identity = 30/64 (46.88%), Postives = 35/64 (54.69%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLL 313
            ICLL    G C  R+  YY+D    +C+ F Y GC GN NNF+T E C  AC  I K   IC L
Sbjct:   35 ICLLPPDDGPCRARIPSYYYDRYTQSCREFMYGGCEGNANNFETLEACNEACWKIEKVPKICRL 98

HSP 2 Score: 54.6842 bits (130), Expect = 6.314e-8
Identity = 25/54 (46.30%), Postives = 30/54 (55.56%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
              C      G CS  VT+YYF+    AC+ F YTGCGGN NNF   +DC   C+
Sbjct:  153 VFCYSPKDEGLCSANVTRYYFNPRHKACEAFNYTGCGGNDNNFVNLKDCKRTCV 206
[Close]
BLAST of Papilin vs. UniProt/SwissProt
Match: sp|Q60495|A4_CAVPO (Amyloid-beta A4 protein OS=Cavia porcellus OX=10141 GN=APP PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 1.569e-10
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRSMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. UniProt/SwissProt
Match: sp|Q95241|A4_SAISC (Amyloid-beta A4 protein OS=Saimiri sciureus OX=9521 GN=APP PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.977e-10
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. UniProt/SwissProt
Match: sp|P08592|A4_RAT (Amyloid-beta A4 protein OS=Rattus norvegicus OX=10116 GN=App PE=1 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 1.987e-10
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. UniProt/SwissProt
Match: sp|P79307|A4_PIG (Amyloid-beta A4 protein OS=Sus scrofa OX=9823 GN=APP PE=2 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 1.987e-10
Identity = 25/45 (55.56%), Postives = 29/45 (64.44%), Query Frame = 2 
Query:  143 TGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            TG C   ++++YFD  E  C PF Y GCGGN NNFDT E C A C
Sbjct:  297 TGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
[Close]
BLAST of Papilin vs. TrEMBL
Match: A0A0N4UQN1 (Uncharacterized protein OS=Dracunculus medinensis OX=318479 GN=DME_LOCUS3812 PE=4 SV=2)

HSP 1 Score: 72.0182 bits (175), Expect = 4.624e-11
Identity = 37/67 (55.22%), Postives = 42/67 (62.69%), Query Frame = 2 
Query:   98 QAMC---CTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            QA C   C   +CLLSV  G C  R T+Y F+   + C PF YTGCGGN NNF+T EDC A C NIG
Sbjct:  774 QAECSRTCPAELCLLSVDPGACGGRQTRYAFNRQSNQCTPFQYTGCGGNLNNFNTMEDCMATCGNIG 840
[Close]
BLAST of Papilin vs. TrEMBL
Match: A0A5N4DYL0 (Tissue factor pathway inhibitor 2 OS=Camelus dromedarius OX=9838 GN=Cadr_000007961 PE=4 SV=1)

HSP 1 Score: 68.1662 bits (165), Expect = 2.521e-10
Identity = 31/64 (48.44%), Postives = 38/64 (59.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLL 313
            ICLL +  G C  R+  YY+D    +C+ F Y GC GN NNF+T+EDC  AC  I K   IC L
Sbjct:   36 ICLLPLDEGPCRARIPSYYYDRYTQSCREFMYGGCEGNANNFETWEDCNEACWRIEKVPKICRL 99

HSP 2 Score: 55.8398 bits (133), Expect = 6.655e-6
Identity = 26/56 (46.43%), Postives = 33/56 (58.93%), Query Frame = 2 
Query:  113 TLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            + + C      G CS  VT+YYF+    AC+ FTYTGCGGN NNF   +DC   C+
Sbjct:  152 SPSFCYSPKDEGLCSANVTRYYFNPRYKACEAFTYTGCGGNDNNFVNMKDCKRVCV 207
[Close]
BLAST of Papilin vs. TrEMBL
Match: A0A0V0YFC8 (Papilin OS=Trichinella pseudospiralis OX=6337 GN=Ppn PE=4 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 3.609e-10
Identity = 30/55 (54.55%), Postives = 38/55 (69.09%), Query Frame = 2 
Query:  113 TLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +L  C   + TGTCS+ + ++Y+D+ E  CKPF YTGCGGNGNNF T EDC   C
Sbjct:  893 SLNRCFHPLDTGTCSKNIQRWYYDDVEEKCKPFAYTGCGGNGNNFATKEDCDQNC 947

HSP 2 Score: 56.9954 bits (136), Expect = 8.731e-6
Identity = 36/102 (35.29%), Postives = 49/102 (48.04%), Query Frame = 2 
Query:    5 PTRRSSDLFFRSQK*RKMKLLI------SVLLFACLI--QAMCCTLT--ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            P R   + ++  Q   K KLLI      +   F  LI  Q  C  L   +C      G+C   + +++FD+ E  CKPF Y GC GNGNNF +   C A C+
Sbjct:  761 PCRGHFERWYYDQNEAKCKLLIYGGCGGNANNFESLIGCQETCTELDADVCKQPADKGSCRGNIQRWHFDHKEKQCKPFLYGGCLGNGNNFKSRNACEAKCM 862
[Close]
BLAST of Papilin vs. TrEMBL
Match: E3N6G8 (BPTI/Kunitz inhibitor domain-containing protein OS=Caenorhabditis remanei OX=31234 GN=CRE_06031 PE=4 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 3.696e-10
Identity = 28/56 (50.00%), Postives = 37/56 (66.07%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            +CLLS+  G C  R T+Y ++   + C PF YTGCGGN NNF + +DC A C N+G
Sbjct:   18 LCLLSIDRGACGGRQTRYAYNRQTNQCVPFEYTGCGGNLNNFVSMQDCMATCGNVG 73
[Close]
BLAST of Papilin vs. TrEMBL
Match: A0A5E4MFC0 (Immunoglobulin-like domain,Immunoglobulin subtype,ADAM-TS Spacer 1,Proteinase inhibitor I2, Kunitz OS=Cinara cedri OX=506608 GN=CINCED_3A008612 PE=4 SV=1)

HSP 1 Score: 69.707 bits (169), Expect = 3.761e-10
Identity = 27/51 (52.94%), Postives = 41/51 (80.39%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CL++V+ G+CS+++ ++YFDN E+ACKPF YTGCG N N+++T E C + C
Sbjct: 1666 CLMAVARGSCSKKIPRWYFDNNENACKPFYYTGCGANANSYETQESCESKC 1716
[Close]
BLAST of Papilin vs. Ensembl Cavefish
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:NCBI gene;Acc:103023332])

HSP 1 Score: 57.7658 bits (138), Expect = 5.690e-10
Identity = 25/68 (36.76%), Postives = 39/68 (57.35%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKKI 325
            +CLL    G C   V++Y+++     C+ F+Y GCGGN NNF T+++C+  C  I K   IC    ++
Sbjct:   26 VCLLPAVEGPCRGLVSRYFYNTLTQRCEEFSYGGCGGNANNFVTFQECHKMCYTIPKIPQICRFPSEV 93

HSP 2 Score: 51.9878 bits (123), Expect = 5.323e-8
Identity = 22/57 (38.60%), Postives = 33/57 (57.89%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK 292
            IC   +  G CS  + +YY+++ +  C+ FTYTGCGG+ NNF + + C   C    K
Sbjct:  146 ICQGVLDKGKCSASIPRYYYNSAKKTCEEFTYTGCGGSSNNFVSKQSCMDVCARKSK 202
[Close]
BLAST of Papilin vs. Ensembl Cavefish
Match: ENSAMXT00000053501.1 (pep primary_assembly:Astyanax_mexicanus-2.0:12:31379453:31384888:1 gene:ENSAMXG00000037311.1 transcript:ENSAMXT00000053501.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.7582 bits (125), Expect = 1.900e-9
Identity = 22/56 (39.29%), Postives = 31/56 (55.36%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINI 286
             +C  +  TG C   + ++YF   E  C PF Y GCGGN NNF++ E C + C  +
Sbjct:    4 PVCWANAETGPCRAMLPRWYFVKEEGRCAPFIYGGCGGNRNNFESEEYCLSVCSTV 59
[Close]
BLAST of Papilin vs. Ensembl Cavefish
Match: ENSAMXT00000002208.2 (pep primary_assembly:Astyanax_mexicanus-2.0:13:36140062:36218718:1 gene:ENSAMXG00000002013.2 transcript:ENSAMXT00000002208.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 57.3806 bits (137), Expect = 1.983e-9
Identity = 21/52 (40.38%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C L +  G CS     +YF++   AC+PF Y+GCGGN N +   E+C   C+
Sbjct: 2228 CALPLDEGDCSRYTLHWYFNSQVGACRPFVYSGCGGNANRYTQKEECEKHCL 2279
[Close]
BLAST of Papilin vs. Ensembl Cavefish
Match: col28a2b (collagen, type XXVIII, alpha 2b [Source:ZFIN;Acc:ZDB-GENE-130530-762])

HSP 1 Score: 56.6102 bits (135), Expect = 3.307e-9
Identity = 22/52 (42.31%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C L++  G C E   ++Y+D   +AC  F Y GC GN N FDT E+C   C+
Sbjct: 1083 CELTLDQGPCREYNIRWYYDKQANACAQFWYGGCDGNRNRFDTEEECKKTCV 1134
[Close]
BLAST of Papilin vs. Ensembl Cavefish
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:103022515])

HSP 1 Score: 56.6102 bits (135), Expect = 3.601e-9
Identity = 22/52 (42.31%), Postives = 29/52 (55.77%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +C L   TG C   + +++FD  +  C  F Y GC GN NNFD+ E C A C
Sbjct:  314 VCSLEAETGPCRASMPRWHFDMQQRKCVRFIYGGCAGNRNNFDSEEYCMAVC 365
[Close]
BLAST of Papilin vs. Ensembl Sea Lamprey
Match: tfpi2 (tissue factor pathway inhibitor 2 [Source:ZFIN;Acc:ZDB-GENE-060503-38])

HSP 1 Score: 52.7582 bits (125), Expect = 6.604e-9
Identity = 25/71 (35.21%), Postives = 42/71 (59.15%), Query Frame = 2 
Query:   80 LFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK 292
            +F+C+ +    T   CL    TG C     ++Y++  + +C PF+Y+GCGGN NNF + + C + C++ GK
Sbjct:  134 VFSCIEKPN--TPRECLSRHDTGNCQGNFRRFYYNIQKRSCLPFSYSGCGGNNNNFISAKTCLSTCLSAGK 202

HSP 2 Score: 50.0618 bits (118), Expect = 5.497e-8
Identity = 21/53 (39.62%), Postives = 29/53 (54.72%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            +C     TG C   +T+Y+++     C PF Y GCGGN N F+  E C  +CI
Sbjct:   86 LCRPDAETGRCRAHITRYFYNMTLGMCMPFVYGGCGGNNNRFEDMESCVFSCI 138

HSP 3 Score: 48.1358 bits (113), Expect = 2.563e-7
Identity = 23/61 (37.70%), Postives = 31/61 (50.82%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLIC 307
            C L    G C     +Y+F+     C+ F Y GC  N NNF+T ++C AAC  I K   +C
Sbjct:   27 CTLPAKPGDCRAAFPRYFFNRSTLRCESFIYGGCHSNENNFETMQECRAACSFIKKIPKLC 87
[Close]
BLAST of Papilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005038.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005038.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 5.999e-8
Identity = 20/57 (35.09%), Postives = 32/57 (56.14%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
             ICL+    G C+  + +++++     C+ FTY GCGGN NNF +   C + C  +G
Sbjct:  165 RICLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQVG 221

HSP 2 Score: 47.7506 bits (112), Expect = 3.979e-7
Identity = 19/54 (35.19%), Postives = 31/54 (57.41%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINI 286
            C++ +  G C   + + +++     C+PF Y GC GNGNNF++  +C A C  I
Sbjct:    3 CMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKCAWI 56

HSP 3 Score: 43.8986 bits (102), Expect = 7.658e-6
Identity = 19/53 (35.85%), Postives = 28/53 (52.83%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            C L +  G C   + +Y+F+    +C+ F Y GC GN NNF     CY  C++
Sbjct:   75 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVH 127
[Close]
BLAST of Papilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005043.1 (pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 gene:ENSPMAG00000004579.1 transcript:ENSPMAT00000005043.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 50.0618 bits (118), Expect = 6.249e-8
Identity = 20/56 (35.71%), Postives = 32/56 (57.14%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIG 289
            ICL+    G C+  + +++++     C+ FTY GCGGN NNF +   C + C  +G
Sbjct:  165 ICLMKADPGECTAVIPRFHYNPKTSNCESFTYGGCGGNDNNFSSERSCMSVCGQVG 220

HSP 2 Score: 47.3654 bits (111), Expect = 4.350e-7
Identity = 19/54 (35.19%), Postives = 31/54 (57.41%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINI 286
            C++ +  G C   + + +++     C+PF Y GC GNGNNF++  +C A C  I
Sbjct:    3 CMMDLDPGPCRAYLPRVFYNRYTQRCEPFHYGGCFGNGNNFESLAECNAKCAWI 56

HSP 3 Score: 43.5134 bits (101), Expect = 9.030e-6
Identity = 19/53 (35.85%), Postives = 28/53 (52.83%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            C L +  G C   + +Y+F+    +C+ F Y GC GN NNF     CY  C++
Sbjct:   74 CRLDMEVGVCRALLRRYFFNMTSGSCEEFGYGGCQGNLNNFKDAASCYQHCVH 126
[Close]
BLAST of Papilin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009465.1 (pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 gene:ENSPMAG00000008558.1 transcript:ENSPMAT00000009465.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 47.3654 bits (111), Expect = 5.161e-7
Identity = 23/52 (44.23%), Postives = 28/52 (53.85%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            ICLL  + G C    T++ +D     CK FTY GCGGN NNF    +C   C
Sbjct:   71 ICLLEEAVGPCRGSFTRWIYDAESSNCKEFTYGGCGGNFNNFLEETECMVTC 122

HSP 2 Score: 46.595 bits (109), Expect = 1.184e-6
Identity = 23/52 (44.23%), Postives = 28/52 (53.85%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +CLL   T  C    T++ +D     CK FTY GCGGN NNF    +C A C
Sbjct:  165 VCLLEAVTSPCRGSFTRWTYDAESGHCKEFTYGGCGGNFNNFLEETECVAMC 216

HSP 3 Score: 45.0542 bits (105), Expect = 3.945e-6
Identity = 22/51 (43.14%), Postives = 28/51 (54.90%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CLL+ +TG C    T++ +D     CK FTY GC GN NNF    +C   C
Sbjct:    1 CLLNPTTGPCRGSFTRWTYDAATSTCKEFTYGGCRGNQNNFLEEAECLMDC 51
[Close]
BLAST of Papilin vs. Ensembl Sea Lamprey
Match: WFIKKN1 (WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 [Source:HGNC Symbol;Acc:HGNC:30912])

HSP 1 Score: 46.9802 bits (110), Expect = 1.199e-6
Identity = 22/44 (50.00%), Postives = 26/44 (59.09%), Query Frame = 2 
Query:  152 CSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            C    TK+Y+D+G +AC  F Y GC  N N FDTYE C   C N
Sbjct:  350 CGSARTKWYYDSGLNACDTFVYGGCDSNRNRFDTYEGCKRWCQN 393
[Close]
BLAST of Papilin vs. Ensembl Nematostella
Match: EDO47798 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL44])

HSP 1 Score: 56.6102 bits (135), Expect = 2.166e-11
Identity = 23/52 (44.23%), Postives = 34/52 (65.38%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +C L +  G C E + ++YF+    AC+ F Y+GC GN NNF+TY+ C+A C
Sbjct:    2 LCFLPLQRGPCKEFLPQWYFNASSGACEIFLYSGCDGNNNNFETYDKCFATC 53
[Close]
BLAST of Papilin vs. Ensembl Nematostella
Match: EDO40368 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7B9])

HSP 1 Score: 53.9138 bits (128), Expect = 2.129e-10
Identity = 23/51 (45.10%), Postives = 29/51 (56.86%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            CLL   TG+CS    ++++D     C PF YTGCGGN NNF   + C   C
Sbjct:    1 CLLRSRTGSCSRFTVRWFYDTNRGKCAPFVYTGCGGNENNFMNEQKCLETC 51
[Close]
BLAST of Papilin vs. Ensembl Nematostella
Match: EDO42139 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S2F4])

HSP 1 Score: 57.3806 bits (137), Expect = 6.747e-10
Identity = 21/51 (41.18%), Postives = 29/51 (56.86%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            C+L  +TG C     K+Y+   ++AC  F Y GCGGN N FD+  +C   C
Sbjct:  743 CVLENATGPCRGAFPKWYYSTADNACHEFLYGGCGGNANKFDSKSECLEVC 793
[Close]
BLAST of Papilin vs. Ensembl Nematostella
Match: EDO41922 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S322])

HSP 1 Score: 52.7582 bits (125), Expect = 6.829e-10
Identity = 24/55 (43.64%), Postives = 30/55 (54.55%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            + C L   TG C   +  +Y+D  E  CK F Y GC GN N FDT E C  AC++
Sbjct:    7 SFCSLPAVTGRCMAYIPSFYYDMKEEKCKEFIYGGCNGNLNRFDTQEKCEEACMS 61
[Close]
BLAST of Papilin vs. Ensembl Nematostella
Match: EDO29819 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2J6])

HSP 1 Score: 49.6766 bits (117), Expect = 1.070e-8
Identity = 21/55 (38.18%), Postives = 31/55 (56.36%), Query Frame = 2 
Query:  119 TICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            + C L    G C   + + +F++    C+ F Y GCGGN NNF T E+C  AC++
Sbjct:   12 SACTLPKKVGDCRAAMPRVFFNSQSGKCEDFIYGGCGGNANNFHTMEECKKACMS 66
[Close]
BLAST of Papilin vs. Ensembl Medaka
Match: ENSORLT00000044137.1 (pep primary_assembly:ASM223467v1:2:16334979:16376346:1 gene:ENSORLG00000025630.1 transcript:ENSORLT00000044137.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 59.3066 bits (142), Expect = 5.034e-10
Identity = 23/52 (44.23%), Postives = 31/52 (59.62%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C L +  GTC +   ++Y+D   +AC  F Y GC GNGN FDT E+C   C+
Sbjct:  958 CSLVLVPGTCRDYNIRWYYDKQANACAQFWYGGCNGNGNRFDTEEECKRTCV 1009
[Close]
BLAST of Papilin vs. Ensembl Medaka
Match: COL6A3 (collagen type VI alpha 3 chain [Source:NCBI gene;Acc:101161016])

HSP 1 Score: 59.3066 bits (142), Expect = 5.139e-10
Identity = 24/52 (46.15%), Postives = 30/52 (57.69%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            IC L    G+C+E   K+Y+D    +C  F Y GC GN N FDT E+C  AC
Sbjct: 2638 ICQLPKQEGSCAEFALKWYYDTTSKSCTRFWYGGCDGNQNRFDTQEECKEAC 2689
[Close]
BLAST of Papilin vs. Ensembl Medaka
Match: col28a2a (collagen alpha-1(XXVIII) chain [Source:NCBI gene;Acc:101157899])

HSP 1 Score: 58.9214 bits (141), Expect = 6.499e-10
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 2 
Query:  125 CLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACI 280
            C +++  GTC + V ++Y+D   +AC  F Y GCGGN N F+T  +C   C+
Sbjct:  970 CSITLDQGTCRDYVIRWYYDQQANACAQFWYGGCGGNENRFETESECKKTCV 1021
[Close]
BLAST of Papilin vs. Ensembl Medaka
Match: spint1a (kunitz-type protease inhibitor 1 [Source:NCBI gene;Acc:101175207])

HSP 1 Score: 58.151 bits (139), Expect = 1.033e-9
Identity = 31/76 (40.79%), Postives = 40/76 (52.63%), Query Frame = 2 
Query:   95 IQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACINIGK*YLICLLFKK 322
            I  M     IC  +  TGTC E  TK+Y++  +  C PF Y+GCGGN N FDT   C + C  + K  +  LL  K
Sbjct:  348 IAPMKEEREICTETPDTGTCRESSTKWYYEPYQEDCFPFNYSGCGGNENKFDTKNYCQSFCRGVTKADVFALLNNK 423
[Close]
BLAST of Papilin vs. Ensembl Medaka
Match: aplp2 (amyloid beta precursor like protein 2 [Source:NCBI gene;Acc:101168561])

HSP 1 Score: 56.9954 bits (136), Expect = 2.192e-9
Identity = 22/52 (42.31%), Postives = 29/52 (55.77%), Query Frame = 2 
Query:  122 ICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            +C L   TG C   + +++FD  +  C  F Y GC GN NNFD+ E C A C
Sbjct:  313 VCTLEAETGPCRASMPRWHFDLSQRKCVRFIYGGCAGNRNNFDSEEYCMAVC 364
[Close]
BLAST of Papilin vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.658e-10
Identity = 29/77 (37.66%), Postives = 42/77 (54.55%), Query Frame = 2 
Query:   53 KMKLLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            K K+L+ V+LF+ L Q +   L  C     +G C     ++YF++    C+ F Y GCG NGNNF T ++C   CI 
Sbjct:    2 KSKILVLVVLFS-LSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 77
[Close]
BLAST of Papilin vs. Planmine SMEST
Match: SMESG000037999.1 (SMESG000037999.1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.777e-10
Identity = 29/77 (37.66%), Postives = 42/77 (54.55%), Query Frame = 2 
Query:   53 KMKLLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            K K+L+ V+LF+ L Q +   L  C     +G C     ++YF++    C+ F Y GCG NGNNF T ++C   CI 
Sbjct:    4 KSKILVLVVLFS-LSQLLESRLKECNEPKQSGMCEAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79
[Close]
BLAST of Papilin vs. Planmine SMEST
Match: SMESG000037995.1 (SMESG000037995.1)

HSP 1 Score: 54.6842 bits (130), Expect = 4.562e-10
Identity = 29/77 (37.66%), Postives = 42/77 (54.55%), Query Frame = 2 
Query:   53 KMKLLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            K K+L+ V+LF+ L Q +   L  C     +G C     ++YF++    C+ F Y GCG NGNNF T ++C   CI 
Sbjct:    4 KSKILVLVVLFS-LSQLLESRLKECNEPKQSGMCMAYFKRFYFNSETGKCETFIYGGCGKNGNNFQTEDECEELCIE 79
[Close]
BLAST of Papilin vs. Planmine SMEST
Match: SMESG000044323.1 (SMESG000044323.1)

HSP 1 Score: 52.7582 bits (125), Expect = 1.742e-9
Identity = 25/74 (33.78%), Postives = 35/74 (47.30%), Query Frame = 2 
Query:   56 MKLLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAAC 277
            MKL++++    C IQ + C   IC   V  G C   + ++ +      C PF +TGC GN NNF     C   C
Sbjct:    1 MKLVLAICFVICFIQTLDCLNKICTKPVERGNCKASMDRFSYSTEHGKCIPFKFTGCRGNENNFINEAACNKIC 74
[Close]
BLAST of Papilin vs. Planmine SMEST
Match: SMESG000013916.1 (SMESG000013916.1)

HSP 1 Score: 52.7582 bits (125), Expect = 2.285e-9
Identity = 26/76 (34.21%), Postives = 38/76 (50.00%), Query Frame = 2 
Query:   56 MKLLISVLLFACLIQAMCCTLTICLLSVSTGTCSERVTKYYFDNGEHACKPFTYTGCGGNGNNFDTYEDCYAACIN 283
            M L+ S L    L       +  C L    G CS    +Y+++N    C+ F Y GCG NGN+F ++++CY  C N
Sbjct:    1 MNLIYSTLTITFLASQYLSIMPECNLQKFRGRCSAFSRRYFYNNHTGKCEVFIYGGCGRNGNHFMSWKECYTRCKN 76
The following BLAST results are available for this feature:
BLAST of Papilin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
APP4.071e-1155.56amyloid beta precursor protein [Source:HGNC Symbol... [more]
APP4.111e-1155.56amyloid beta precursor protein [Source:HGNC Symbol... [more]
APP4.116e-1155.56amyloid beta precursor protein [Source:HGNC Symbol... [more]
APP4.118e-1155.56amyloid beta precursor protein [Source:HGNC Symbol... [more]
APP4.138e-1155.56amyloid beta precursor protein [Source:HGNC Symbol... [more]
back to top
BLAST of Papilin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mlt-112.015e-1035.82pep chromosome:WBcel235:V:20667211:20678513:1 gene... [more]
mlt-112.034e-1035.82pep chromosome:WBcel235:V:20667211:20678513:1 gene... [more]
mlt-112.692e-1035.82pep chromosome:WBcel235:V:20667209:20678513:1 gene... [more]
mlt-116.284e-1035.82pep chromosome:WBcel235:V:20667209:20678513:1 gene... [more]
mlt-118.423e-1035.82pep chromosome:WBcel235:V:20667211:20678513:1 gene... [more]
back to top
BLAST of Papilin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Ppn1.145e-950.98gene:FBgn0003137 transcript:FBtr0301838[more]
Ppn1.180e-950.98gene:FBgn0003137 transcript:FBtr0301837[more]
Ppn1.190e-938.71gene:FBgn0003137 transcript:FBtr0301839[more]
CG428282.089e-835.71gene:FBgn0262010 transcript:FBtr0303835[more]
CG137482.875e-733.96gene:FBgn0033355 transcript:FBtr0088656[more]
back to top
BLAST of Papilin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tfpi26.891e-1337.36tissue factor pathway inhibitor 2 [Source:ZFIN;Acc... [more]
tfpi26.891e-1337.36tissue factor pathway inhibitor 2 [Source:ZFIN;Acc... [more]
appa4.424e-1043.14amyloid beta (A4) precursor protein a [Source:ZFIN... [more]
col7a17.070e-1040.38collagen, type VII, alpha 1 [Source:ZFIN;Acc:ZDB-G... [more]
col7a17.070e-1040.38collagen, type VII, alpha 1 [Source:ZFIN;Acc:ZDB-G... [more]
back to top
BLAST of Papilin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000014315.14.906e-1142.59collagen type VI alpha 5 chain [Source:NCBI gene;A... [more]
ENSXETT00000014204.14.907e-1142.59collagen type VI alpha 5 chain [Source:NCBI gene;A... [more]
ENSXETT00000014273.14.913e-1142.59collagen type VI alpha 5 chain [Source:NCBI gene;A... [more]
tfpi21.716e-934.52tissue factor pathway inhibitor 2 [Source:NCBI gen... [more]
APLP23.421e-941.51amyloid beta (A4) precursor-like protein 2 [Source... [more]
back to top
BLAST of Papilin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Wfdc82.880e-1141.43WAP four-disulfide core domain 8 [Source:MGI Symbo... [more]
Wfdc83.872e-1141.43WAP four-disulfide core domain 8 [Source:MGI Symbo... [more]
App4.639e-1155.56amyloid beta (A4) precursor protein [Source:MGI Sy... [more]
App4.663e-1155.56amyloid beta (A4) precursor protein [Source:MGI Sy... [more]
App4.664e-1155.56amyloid beta (A4) precursor protein [Source:MGI Sy... [more]
back to top
BLAST of Papilin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q7YRQ8|TFPI2_BOVIN8.642e-1146.88Tissue factor pathway inhibitor 2 OS=Bos taurus OX... [more]
sp|Q60495|A4_CAVPO1.569e-1055.56Amyloid-beta A4 protein OS=Cavia porcellus OX=1014... [more]
sp|Q95241|A4_SAISC1.977e-1055.56Amyloid-beta A4 protein OS=Saimiri sciureus OX=952... [more]
sp|P08592|A4_RAT1.987e-1055.56Amyloid-beta A4 protein OS=Rattus norvegicus OX=10... [more]
sp|P79307|A4_PIG1.987e-1055.56Amyloid-beta A4 protein OS=Sus scrofa OX=9823 GN=A... [more]
back to top
BLAST of Papilin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0N4UQN14.624e-1155.22Uncharacterized protein OS=Dracunculus medinensis ... [more]
A0A5N4DYL02.521e-1048.44Tissue factor pathway inhibitor 2 OS=Camelus drome... [more]
A0A0V0YFC83.609e-1054.55Papilin OS=Trichinella pseudospiralis OX=6337 GN=P... [more]
E3N6G83.696e-1050.00BPTI/Kunitz inhibitor domain-containing protein OS... [more]
A0A5E4MFC03.761e-1052.94Immunoglobulin-like domain,Immunoglobulin subtype,... [more]
back to top
BLAST of Papilin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tfpi25.690e-1036.76tissue factor pathway inhibitor 2 [Source:NCBI gen... [more]
ENSAMXT00000053501.11.900e-939.29pep primary_assembly:Astyanax_mexicanus-2.0:12:313... [more]
ENSAMXT00000002208.21.983e-940.38pep primary_assembly:Astyanax_mexicanus-2.0:13:361... [more]
col28a2b3.307e-942.31collagen, type XXVIII, alpha 2b [Source:ZFIN;Acc:Z... [more]
aplp23.601e-942.31amyloid beta precursor like protein 2 [Source:NCBI... [more]
back to top
BLAST of Papilin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
tfpi26.604e-935.21tissue factor pathway inhibitor 2 [Source:ZFIN;Acc... [more]
ENSPMAT00000005038.15.999e-835.09pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g... [more]
ENSPMAT00000005043.16.249e-835.71pep scaffold:Pmarinus_7.0:GL481015:31246:35903:1 g... [more]
ENSPMAT00000009465.15.161e-744.23pep scaffold:Pmarinus_7.0:GL478507:22936:25713:-1 ... [more]
WFIKKN11.199e-650.00WAP, follistatin/kazal, immunoglobulin, kunitz and... [more]
back to top
BLAST of Papilin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Papilin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO477982.166e-1144.23Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403682.129e-1045.10Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO421396.747e-1041.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO419226.829e-1043.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO298191.070e-838.18Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Papilin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000044137.15.034e-1044.23pep primary_assembly:ASM223467v1:2:16334979:163763... [more]
COL6A35.139e-1046.15collagen type VI alpha 3 chain [Source:NCBI gene;A... [more]
col28a2a6.499e-1040.38collagen alpha-1(XXVIII) chain [Source:NCBI gene;A... [more]
spint1a1.033e-940.79kunitz-type protease inhibitor 1 [Source:NCBI gene... [more]
aplp22.192e-942.31amyloid beta precursor like protein 2 [Source:NCBI... [more]
back to top
BLAST of Papilin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000037999.11.658e-1037.66SMESG000037999.1[more]
SMESG000037999.11.777e-1037.66SMESG000037999.1[more]
SMESG000037995.14.562e-1037.66SMESG000037995.1[more]
SMESG000044323.11.742e-933.78SMESG000044323.1[more]
SMESG000013916.12.285e-934.21SMESG000013916.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024859 ID=SMED30024859|Name=Papilin|organism=Schmidtea mediterranea sexual|type=transcript|length=623bp
TTTCCCTACACGACGCTCTTCTGATCTTTTCTTTCGCTCTCAAAAATAAA
GAAAAATGAAACTCTTGATCTCGGTTTTATTATTTGCGTGCTTGATCCAA
GCTATGTGTTGTACTCTAACTATTTGCCTTTTATCTGTATCAACGGGGAC
GTGCTCTGAGAGAGTGACTAAATATTATTTTGATAATGGGGAACATGCCT
GTAAACCATTCACTTATACTGGCTGCGGCGGAAACGGAAATAACTTCGAT
ACCTATGAGGACTGCTATGCAGCTTGTATTAACATTGGAAAATAATATCT
CATTTGTTTACTTTTCAAAAAGATCGTGACATTTGAATAAAAATAAAAAA
TAAAAAAAGTGTATGTCGATAAAAAACCTTTAAAAAATATAAATTTAATG
ACAATTATAACATTCAACGTACCATTTTGCTCGTAATATTTGTCATTTCT
GGTGGTATTTTATGAAAGCTAGTGTAACAAACCTTGGCATTAATAGTCAA
TGTGTTAATGAAAGCTAATTATAGTTTATATATTGTTTTATTATTTGCAT
GTTAGGATATTATAAACTTCGTTGATATAATCTATTTCAATTTAGGGGCC
TAAGAGAAAGGATGACGATTGTG
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR036880Kunitz_BPTI_sf
IPR002223Kunitz_BPTI
IPR020901Prtase_inh_Kunz-CS
Vocabulary: molecular function
TermDefinition
GO:0004867serine-type endopeptidase inhibitor activity
GO:0003677DNA binding
GO:0008201heparin binding
GO:0030414peptidase inhibitor activity
GO:0046872metal ion binding
GO:0046914transition metal ion binding
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005794Golgi apparatus
GO:0005905clathrin-coated pit
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030424axon
Vocabulary: biological process
TermDefinition
GO:0006378mRNA polyadenylation
GO:0006417regulation of translation
GO:0006468protein phosphorylation
GO:0006878cellular copper ion homeostasis
GO:0006897endocytosis
GO:0006915apoptotic process
GO:0007155cell adhesion
GO:0007176regulation of epidermal growth factor-activated receptor activity
GO:0007219Notch signaling pathway
GO:0007399nervous system development
GO:0007409axonogenesis
GO:0007617mating behavior
GO:0007626locomotory behavior
GO:0008088axo-dendritic transport
GO:0008344adult locomotory behavior
GO:0008542visual learning
GO:0010466negative regulation of peptidase activity
GO:0010951negative regulation of endopeptidase activity
GO:0016199axon midline choice point recognition
GO:0016322neuron remodeling
GO:0016358dendrite development
GO:0030198extracellular matrix organization
GO:0031175neuron projection development
GO:0035235ionotropic glutamate receptor signaling pathway
GO:0040014regulation of multicellular organism growth
GO:0045931positive regulation of mitotic cell cycle
GO:0048669collateral sprouting in absence of injury
GO:0050803regulation of synapse structure or activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002223Pancreatic trypsin inhibitor Kunitz domainPRINTSPR00759BASICPTASEcoord: 29..39
score: 59.7
coord: 1..13
score: 28.89
coord: 39..54
score: 48.36
IPR002223Pancreatic trypsin inhibitor Kunitz domainSMARTSM00131KU_2coord: 2..55
e-value: 3.5E-22
score: 89.7
IPR002223Pancreatic trypsin inhibitor Kunitz domainPFAMPF00014Kunitz_BPTIcoord: 3..54
e-value: 8.5E-19
score: 67.5
IPR002223Pancreatic trypsin inhibitor Kunitz domainPROSITEPS50279BPTI_KUNITZ_2coord: 4..54
score: 14.87
IPR002223Pancreatic trypsin inhibitor Kunitz domainCDDcd00109KUcoord: 2..55
e-value: 1.12846E-18
score: 68.8158
IPR036880Pancreatic trypsin inhibitor Kunitz domain superfamilyGENE3DG3DSA:4.10.410.10coord: 1..58
e-value: 1.1E-21
score: 78.4
IPR036880Pancreatic trypsin inhibitor Kunitz domain superfamilySUPERFAMILYSSF57362BPTI-likecoord: 3..56
NoneNo IPR availablePANTHERPTHR10083KUNITZ-TYPE PROTEASE INHIBITOR-RELATEDcoord: 4..54
NoneNo IPR availablePANTHERPTHR10083:SF217TISSUE FACTOR PATHWAY INHIBITOR 2coord: 4..54
IPR020901Proteinase inhibitor I2, Kunitz, conserved sitePROSITEPS00280BPTI_KUNITZ_1coord: 32..50