Nudix hydrolase domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024846 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Fly
Match: CG12567 (gene:FBgn0039958 transcript:FBtr0344847) HSP 1 Score: 199.134 bits (505), Expect = 2.293e-60 Identity = 116/283 (40.99%), Postives = 161/283 (56.89%), Query Frame = 2 Query: 116 IVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDT--HNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKH---GNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDD 949 I+++K NN +SG F V VG+I +V K+L ++P+VF + ++++ P + E++ + KV LR AL+ WR+EY+ V + R ALLK+ERAA+ L GV KYGV +NGY +H G C +W+ QRS TK T+PG DNM GGGL+ + + + A E EEAS+P DL+ L S G +S +FE +G+ P Y +DL LP F P N+DGEV F + + FK TSA V+IDFLIRHG IT DD Sbjct: 13 ILAQKFNNFYLSGIHKCDIRPFVVEGKQVGLIKSDVLKHLEKYPEVFCIRACEQTKQGLVELNPAFRDYNERTEQLEKVLRNLRSEGLFPALQGWRDEYFEVKADCR--ALLKMERAATPLFGVRKYGVDINGYV--RHPTLGLC--IWLQQRSNTKETWPGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESRQGLFPNTEYVFDLELPLDFVPQNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIRHGHITADD 289
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Fly
Match: CG12567 (gene:FBgn0039958 transcript:FBtr0113704) HSP 1 Score: 199.134 bits (505), Expect = 2.293e-60 Identity = 116/283 (40.99%), Postives = 161/283 (56.89%), Query Frame = 2 Query: 116 IVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDT--HNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKH---GNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDD 949 I+++K NN +SG F V VG+I +V K+L ++P+VF + ++++ P + E++ + KV LR AL+ WR+EY+ V + R ALLK+ERAA+ L GV KYGV +NGY +H G C +W+ QRS TK T+PG DNM GGGL+ + + + A E EEAS+P DL+ L S G +S +FE +G+ P Y +DL LP F P N+DGEV F + + FK TSA V+IDFLIRHG IT DD Sbjct: 13 ILAQKFNNFYLSGIHKCDIRPFVVEGKQVGLIKSDVLKHLEKYPEVFCIRACEQTKQGLVELNPAFRDYNERTEQLEKVLRNLRSEGLFPALQGWRDEYFEVKADCR--ALLKMERAATPLFGVRKYGVDINGYV--RHPTLGLC--IWLQQRSNTKETWPGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESRQGLFPNTEYVFDLELPLDFVPQNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIRHGHITADD 289
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Fly
Match: CG12567 (gene:FBgn0039958 transcript:FBtr0300704) HSP 1 Score: 193.356 bits (490), Expect = 3.224e-58 Identity = 112/277 (40.43%), Postives = 156/277 (56.32%), Query Frame = 2 Query: 179 FFVGSYHVGIILPEVAKYLLQFPDVFITDT--HNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKH---GNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 F V VG+I +V K+L ++P+VF + ++++ P + E++ + KV LR AL+ WR+EY+ V + R ALLK+ERAA+ L GV KYGV +NGY +H G C +W+ QRS TK T+PG DNM GGGL+ + + + A E EEAS+P DL+ L S G +S +FE +G+ P Y +DL LP F P N+DGEV F + + FK TSA V+IDFLIRHG IT DD ++ +H L Sbjct: 26 FVVEGKQVGLIKSDVLKHLEKYPEVFCIRACEQTKQGLVELNPAFRDYNERTEQLEKVLRNLRSEGLFPALQGWRDEYFEVKADCR--ALLKMERAATPLFGVRKYGVDINGYV--RHPTLGLC--IWLQQRSNTKETWPGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESRQGLFPNTEYVFDLELPLDFVPQNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIRHGHITADDVVDFTQIVELLHVPL 296
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Fly
Match: CG12567 (gene:FBgn0039958 transcript:FBtr0300702) HSP 1 Score: 192.971 bits (489), Expect = 3.578e-58 Identity = 110/262 (41.98%), Postives = 151/262 (57.63%), Query Frame = 2 Query: 179 FFVGSYHVGIILPEVAKYLLQFPDVFITDT--HNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKH---GNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDD 949 F V VG+I +V K+L ++P+VF + ++++ P + E++ + KV LR AL+ WR+EY+ V + R ALLK+ERAA+ L GV KYGV +NGY +H G C +W+ QRS TK T+PG DNM GGGL+ + + + A E EEAS+P DL+ L S G +S +FE +G+ P Y +DL LP F P N+DGEV F + + FK TSA V+IDFLIRHG IT DD Sbjct: 20 FVVEGKQVGLIKSDVLKHLEKYPEVFCIRACEQTKQGLVELNPAFRDYNERTEQLEKVLRNLRSEGLFPALQGWRDEYFEVKADCR--ALLKMERAATPLFGVRKYGVDINGYV--RHPTLGLC--IWLQQRSNTKETWPGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESRQGLFPNTEYVFDLELPLDFVPQNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIRHGHITADD 275
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Zebrafish
Match: tpk2 (thiamin pyrophosphokinase 2 [Source:ZFIN;Acc:ZDB-GENE-060503-173]) HSP 1 Score: 224.557 bits (571), Expect = 1.287e-70 Identity = 125/303 (41.25%), Postives = 169/303 (55.78%), Query Frame = 2 Query: 86 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 M + +E++ ++ ++ NN + GS L C F V VG I P+VA L +FP VF + I +L TF +S AV +V LR + L WR+E Y V L+ +ERAA++L GV +YGVHVNGYT D GN MW+ +RSLTK TYPG +DNMA GGL V EC+EEA +P L + VGT+S +ED G+ PE + +DL LP +F+P DGEV F ++K L V E FKP A+V++DFLIRH I PD +P+Y + +H L Sbjct: 1 MASWSEKMLQLL-RRMNNFHLPGSILESCLRFEVAGEQVGWISPKVASVLGRFPSVF----RPYGSAITFCSSLDTFASRSVAVDEVLQELRREASFTCLIGWRDEQYAVMPRYCDPPLMYMERAATSLFGVKRYGVHVNGYTRDSSGNLN-MWLARRSLTKQTYPGRLDNMAAGGLAAGCSVRHTMVKECEEEACIPPGLAEQARPVGTVSYTYEDDEGIFPECQFVFDLELPLNFQPHIGDGEVQAFYYYPIEKVKDLLVSEEFKPNCAMVVLDFLIRHAIIEPDSEPYYHEFVAGLHRSL 297
BLAST of Nudix hydrolase domain-containing protein vs. UniProt/SwissProt
Match: sp|P47173|YJ9J_YEAST (Uncharacterized protein YJR142W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YJR142W PE=1 SV=1) HSP 1 Score: 153.68 bits (387), Expect = 4.332e-42 Identity = 94/295 (31.86%), Postives = 150/295 (50.85%), Query Frame = 2 Query: 167 MCTHFFVGSYHVGIILPEVAKYLLQ-----FPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLL----------AYLKSVGTLSL--FFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPF 1000 MCTH +G +L + F + F D +E K + F+ ++ + ++ + ++L+ +K WRNE Y V+V + L VERA + +LG++ YG+H+NGY +D W+ +RS TK T+P ++DN+ GGL + Y + + E EEA++ ++ +YL G +S+ F ++ + EV Y YDL L P +DGEV F E + + FKP ALV++DFLIRHG+ITP+++P+Y MH +LPF Sbjct: 53 MCTH---DGTKIGFVLKFAINEMETVCSEIFEETFQLDESRHELRFKSE----DFDHRNNLIDQLARKMYLESSLSGVKGWRNEKYAVWVNKKPYVL--VERAVAGVLGIITYGIHINGYVLDPKSKKVQFWVPRRSKTKQTWPLMLDNIIAGGLGYPYGIYETVLKESMEEANLEKSVIEDNIKATGSVSYLYFTGDISVTKFNKESDFIVGEVQYVYDLKLSEDIIPKPNDGEVESFNLFSLQETINALRKKEFKPNCALVMVDFLIRHGYITPENEPNYLELVTRMHRRLPF 338
BLAST of Nudix hydrolase domain-containing protein vs. UniProt/SwissProt
Match: sp|P0C026|NUD24_ARATH (Nudix hydrolase 24, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=NUDT24 PE=2 SV=1) HSP 1 Score: 151.369 bits (381), Expect = 6.030e-41 Identity = 98/283 (34.63%), Postives = 142/283 (50.18%), Query Frame = 2 Query: 128 KCNNAIIS-GSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDER-FKPTSALVLIDFLIRHGFITPDDDPHYSAY 970 +CN + G +P F + VG I KYL F D+F + + + L EE++ AVA V IL N + RNE Y V + A +ERAA+ G+ Y +HVNGY V++ G +++WIG+RSL K TYPG +D++ GGL V + EC+EEA + L +VG +S D +V++CYDL LP F P N DGEV F + +++ ++ FK + +LV+IDFL RHG I P+ + Y Sbjct: 85 RCNRGLEKLGEFIP----FVIEEQIVGYIHKGFTKYLRDFNDIFTFSQYGGHVTLNMM--LDKPEERTRAVAHVIKIL---GNKGIIPGIRNELYPVKPSFNAPAFFSIERAAAPYFGLKGYAIHVNGY-VERDGQ-KFLWIGKRSLAKSTYPGKLDHLVAGGLPHGISVCENLVKECEEEAGISKVLADRAIAVGVVSYMDIDRYCFTRDVLFCYDLELPQDFVPTNQDGEVDSFRLIPVAQVANVVRKTSFFKDSCSLVIIDFLFRHGLIRPESPGYLDLY 356
BLAST of Nudix hydrolase domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VXZ0|NUD20_ARATH (Nudix hydrolase 20, chloroplastic OS=Arabidopsis thaliana OX=3702 GN=NUDT20 PE=2 SV=1) HSP 1 Score: 146.362 bits (368), Expect = 5.204e-39 Identity = 93/273 (34.07%), Postives = 140/273 (51.28%), Query Frame = 2 Query: 179 FFVGSYHVGIILPEVAKYLLQFPDVFITDTHNN-----ETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARN---ECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDER-FKPTSALVLIDFLIRHGFITPDDDPHYSAY 970 F + VG I +YL +F D+F + + + + + L E+++ AVA V IL D + + RNE Y V + +ERAA+ G+ YGVH+NGY V++ G + +WIG+RSL+K TYPG++D++ GGL + C N EC+EEA + + +VG +S D +V++CYDL LP F P N DGEV F + +++ + FK +LV+IDFL RHGFI P+ + Y Sbjct: 101 FVIEEQIVGYIHKRFTEYLREFHDIFTFSQNGSCPDRVDGYVTLNLMLQKPEDRTRAVADVIKILGDKGIIPGI---RNELYPVKPSFNAPVFFSLERAAAPYFGIKGYGVHMNGY-VERDGQ-KLLWIGKRSLSKSTYPGMLDHLVAGGLPHG---ISCGGNLVKECEEEAGISRAIADRAIAVGAVSYLDIDQYCFKRDVLFCYDLELPEDFVPKNQDGEVESFKLIPVAQVASVIKKTSFFKANCSLVIIDFLFRHGFIRPESSGYLDLY 365
BLAST of Nudix hydrolase domain-containing protein vs. UniProt/SwissProt
Match: sp|P41888|TNR3_SCHPO (Thiamine pyrophosphokinase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tnr3 PE=4 SV=1) HSP 1 Score: 125.561 bits (314), Expect = 2.530e-30 Identity = 90/284 (31.69%), Postives = 137/284 (48.24%), Query Frame = 2 Query: 149 SGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLS-LFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLP 997 +G +P F +G + P V + L++ + + I+I N STFE+++ +AKV R WRNE Y V+ +++ K +L VER L G + GVH Y + +W+ +RS TK T+P +DN GG+ V+ E EEA++ + + L GT+S + E + PE+ Y +DL + P +DGEV+ F + +++ H + FKP ALVL+DFLIRHG ITP P Y +H LP Sbjct: 25 NGEFVPGTIPFRANGAAIGYVTPLVLEILIKADNFKFNWVYVPGEYIEI--NASTFEKRTDILAKVLEHWRHNNTFGIADQWRNELYTVYGKSK-KPVLAVERGGFWLFGFLSTGVHCTMYIPATKEHPLRIWVPRRSPTKQTWPNYLDNSVAGGIAHGDSVIGTMIKEFSEEANLDVSSMN-LIPCGTVSYIKMEKRHWIQPELQYVFDLPVDDLVIPRINDGEVAGFSLLPLNQVLHELELKSFKPNCALVLLDFLIRHGIITP-QHPQYLQTLERIHRPLP 303
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Match: Q5D8P4 (Nudix hydrolase 20 isoform 2 OS=Schistosoma japonicum OX=6182 GN=EWB00_011171 PE=2 SV=1) HSP 1 Score: 284.648 bits (727), Expect = 3.482e-90 Identity = 148/328 (45.12%), Postives = 198/328 (60.37%), Query Frame = 2 Query: 107 LWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTH--NNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDK-----------HGNCE----------------YMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 L ++V KCNN +++GSS C F + Y VG I P V +LL++ VF+ +H + + + + L+ +++S AVA+V LR T+ ALK WRNE YGV++ NR K LLK+ER+AS LLGV++YGVHVNG+ + +GN +MW+G RS+ K T+PG++DNMA GGL + D ++CAR ECQEEASVP +L L V LS FED RG+ P++ YC+DL LP F PV+SDGEV F V SE+K L DERFK SALV++DFL RH FI D DP ++ MH LP D Sbjct: 9 LRNLVLNKCNNFLLAGSSRDKCYKFLLDGYFVGFIQPGVLDWLLKYAKVFVKISHPQHGDQCVTVHQTLTNVKDRSDAVAEVMQDLRATSPFKALKGWRNEDYGVYIHNREKLLLKIERSASNLLGVIRYGVHVNGFFSSRCNYYQKSDRVTNGNLHSSDDPKSLDQTDPDNVFMWLGIRSMNKPTWPGMLDNMAAGGLTYGLDAVECARKECQEEASVPAHMLDKLTLVNQLSYIFEDERGVCPQIEYCFDLELPPDFIPVSSDGEVDSFQLVSISEIKQLIFDERFKSNSALVVLDFLYRHKFIDKDSDPRHAEIQSLMHVNLPLD 336
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Match: A0A504YE52 (Nudix hydrolase 20 chloroplastic OS=Fasciola gigantica OX=46835 GN=FGIG_03962 PE=4 SV=1) HSP 1 Score: 284.263 bits (726), Expect = 5.671e-90 Identity = 151/346 (43.64%), Postives = 199/346 (57.51%), Query Frame = 2 Query: 92 NINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFI--TDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGY-----------------------------TVDKHG-----------NCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 N LW + S+KCNN ++ GSS C F V + VG++ P+V LL +P VF+ E I + P+LSTF+ +S+AVA V LR AL+ WRNE YGV++ +R + LL++ER+AS+LLGVV+YGVHVNGY TV K + MW+G RSL K T+PG++DN+A GGL F D L CAR ECQEEASVP +LL + +VG LS FED RG+ P+V YC+DL LP+ F PV +DGEV F V +++K L +RFK SALV++DFL RH FI P DP ++ MH + FD Sbjct: 4 NTFSNLWKLASQKCNNFLLPGSSRCSCCKFLVDGHFVGLVRPDVIPSLLTYPTVFVWAVQPDTGERCITLHPSLSTFDARSSAVADVMLDLRSKKTFRALEGWRNEDYGVYIGDRQQPLLRLERSASSLLGVVRYGVHVNGYFIKCSSELNGINNSKSNGSAVGNGKSPSSTVSKTSVRDQPLSEHDPSSVMMWLGMRSLNKPTWPGMLDNIAAGGLTFGLDALSCARKECQEEASVPEELLNTMSAVGRLSYVFEDERGVCPQVEYCFDLELPADFVPVGADGEVDSFQLVSIAQVKELIFSDRFKANSALVILDFLYRHKFIDPLSDPRHAEIQSLMHMQFEFD 349
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Match: A0A0V0J957 (Uncharacterized protein YJR142W OS=Schistocephalus solidus OX=70667 GN=YJ9J PE=4 SV=1) HSP 1 Score: 276.559 bits (706), Expect = 5.546e-87 Identity = 138/336 (41.07%), Postives = 201/336 (59.82%), Query Frame = 2 Query: 107 LWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFIT--DTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYT--------------------------------VDKHGNCEY---MWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 +W ++++KCNN +SGS+ +C FFV Y VG+I PE LLQ P+VF+ D + + +++ PNL+ F E++ AV V LRD + +L+ WRNE+YGVFV R++ALL VERAAS +LGV ++ VH+ GYT K N +WI +RSL++ +PGL+DN+A GGL + V++CA+ E EEA +P DLL+ L+ G +S ++D G+ + +C+D+ LP FEP N DGEV+ F V E+ L +FKPTSALV++DFL+RHG+++P+D+P Y + WMH KLPFD Sbjct: 8 VWKMLTQKCNNFFLSGSTSEVCVKFFVDKYFVGLIHPEFCGTLLQHPEVFVEGLDPSSEKPCVRLNPNLTNFAERTAAVENVMRNLRDCPSFPSLRGWRNEHYGVFVNGRTEALLSVERAASRVLGVNRHNVHITGYTFLNGAMSSAERQTGLSDVLDMNLEEEEEENEPELKLSNVPRNLRLWIAKRSLSRPKHPGLLDNLAAGGLTYGLTVMECAKKESMEEAGIPEDLLSSLRPGGCVSFAYDDEDGVAAGIDFCFDIELPPHFEPTNVDGEVAEFHLVSLPEVAKLIGCPQFKPTSALVMLDFLVRHGYVSPEDNPFYEKWLQWMHLKLPFD 343
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Match: A0A3Q0KR39 (Thiamin pyrophosphokinase-related OS=Schistosoma mansoni OX=6183 PE=4 SV=1) HSP 1 Score: 275.018 bits (702), Expect = 2.117e-86 Identity = 140/328 (42.68%), Postives = 195/328 (59.45%), Query Frame = 2 Query: 107 LWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTH--NNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCE---------------------------YMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 L ++V KCNN ++ GSS C F + Y VG I P +LL++ +VF+ +H + + I + + ++S AVA+V LR T+ ALK WRNE YGV++ +R + LL++ER+AS+LLG+ +YGVHVNG++++++ + +MW+G RS+ K T PG++DNMA GGL + DV++CAR ECQEEASVP +L L V +S FED RG+ P++ YC+DL LP F PV+SDGEV F SE+K L DE FK SALV +DFL RH FI D DP ++ MH LPFD Sbjct: 9 LRNLVLNKCNNFLLPGSSRDKCYKFLLDGYFVGFIHPMFLDWLLKYANVFVKTSHPQHGDHCITVHQAIINVNDRSNAVAEVMQDLRATSPFKALKGWRNEDYGVYIHDREEVLLRIERSASSLLGITRYGVHVNGFSLNRYNYSKKSDRIVNGSSHNSNDSNSLAQIDPDNVFMWLGLRSINKPTSPGMLDNMAAGGLTYGLDVMECARKECQEEASVPEHMLGKLTLVNQISYIFEDERGVCPQIEYCFDLELPPDFIPVSSDGEVDSFRLASISEIKQLIFDEHFKSNSALVALDFLYRHKFIDKDSDPRHAEVQSLMHVNLPFD 336
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Match: G7Y8Y3 (Nudix hydrolase 20 OS=Clonorchis sinensis OX=79923 GN=NUDT20 PE=4 SV=1) HSP 1 Score: 273.478 bits (698), Expect = 6.621e-86 Identity = 143/326 (43.87%), Postives = 193/326 (59.20%), Query Frame = 2 Query: 104 RLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFI--TDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTV--------------------DKHGNCE----YMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 RLW +VS++CNN ++ GSS C F V + +G+I + LL +P+VF+ +D E I + P+L+T E+++AV+ LR + ALK WRNE YGV+ NR K L +ER+AS LLG+ +YG H+NG+ V D G + MW+G RS +K T+PG++DNMA GGL F D ++CAR ECQEEASVP LL L V LS FED RG+ P+V YC+DL LP F PV++DGEV F V S++K L + E+FK SA+V++DFL RH FI P+ DP + MH K FD Sbjct: 8 RLWTLVSQRCNNFLLPGSSRSSCFKFVVDGFFLGLIRHDALSTLLSYPEVFVWTSDPITGEQCITLHPSLNTPYERTSAVSDAMLDLRAAGTVPALKGWRNEDYGVYAHNRGKTLFCIERSASALLGITRYGCHINGFVVLPETVNGIDQISTHEKLQLKDSFGQIDASRVMMWLGVRSSSKPTWPGMLDNMAAGGLTFGLDPMECARKECQEEASVPEALLGPLTPVSRLSYIFEDDRGVCPQVEYCFDLELPCDFVPVSADGEVDSFRLVSISQVKELILSEQFKANSAMVVLDFLYRHKFIDPESDPLHKDIISLMHVKFDFD 333
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Cavefish
Match: tpk2 (nudix hydrolase 20, chloroplastic-like [Source:NCBI gene;Acc:103029024]) HSP 1 Score: 218.779 bits (556), Expect = 1.576e-68 Identity = 118/303 (38.94%), Postives = 165/303 (54.46%), Query Frame = 2 Query: 86 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 M + +ER+ ++ ++ N+ + GSS+ C F VG VG + VA L +FP+VF + + + P L + E +S A+ V LR L WRNE Y V L+ +ERAA++L GV +YGVHVNG++ D GN MW+ +RS TK TYPG +DN+A GGL V EC+EEA +P L VGT+S +ED G+ PE + +DL LP+ F+P DGEV F +K L E FKP A+V++DFLIRH I PD +P+Y + +H L Sbjct: 1 MNSWSERVLQLL-RRMNSFHLPGSSIERCLRFEVGGQQVGWVPESVASVLGRFPEVFCPP---HTGTVSLCPGLDSLERRSEAMEAVLQDLRGGATFTCLSGWRNEKYAVMPRYCDPPLMHMERAATSLFGVKRYGVHVNGFSRDGSGNLS-MWVARRSKTKQTYPGKLDNLAAGGLAAGCSVKHTLVKECEEEACIPSSLAERATPVGTISYTYEDEDGVFPECQFVFDLELPTDFKPKIGDGEVQDFYYYPIETVKELLASEEFKPNCAMVVLDFLIRHSVIHPDSEPYYQEFVAGLHRSL 298
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Cavefish
Match: tpk2 (nudix hydrolase 20, chloroplastic-like [Source:NCBI gene;Acc:103029024]) HSP 1 Score: 206.838 bits (525), Expect = 1.728e-63 Identity = 111/267 (41.57%), Postives = 146/267 (54.68%), Query Frame = 2 Query: 146 ISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPD 946 +SGSS+ C F VG VG + VA L +FP+VF + + + P L + E +S A+ V LR L WRNE Y V L+ +ERAA++L GV +YGVHVNG++ D GN MW+ +RS TK TYPG +DN+A GGL V EC+EEA +P L VGT+S +ED G+ PE + +DL LP+ F+P DGEV F +K L E FKP A+V++DFLIRH I PD Sbjct: 14 LSGSSIERCLRFEVGGQQVGWVPESVASVLGRFPEVFCPP---HTGTVSLCPGLDSLERRSEAMEAVLQDLRGGATFTCLSGWRNEKYAVMPRYCDPPLMHMERAATSLFGVKRYGVHVNGFSRDGSGNLS-MWVARRSKTKQTYPGKLDNLAAGGLAAGCSVKHTLVKECEEEACIPSSLAERATPVGTISYTYEDEDGVFPECQFVFDLELPTDFKPKIGDGEVQDFYYYPIETVKELLASEEFKPNCAMVVLDFLIRHSVIHPD 276
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Sea Lamprey
Match: tpk2 (thiamin pyrophosphokinase 2 [Source:ZFIN;Acc:ZDB-GENE-060503-173]) HSP 1 Score: 138.272 bits (347), Expect = 1.011e-39 Identity = 75/178 (42.13%), Postives = 100/178 (56.18%), Query Frame = 2 Query: 464 STLLGVVKYGVHVNGYTV-DKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 S L GV +YGVH+NGYT HG C +WIG+RS +K TYPG +DNMA GGL + + E EEA +P L VGT+S E+ RG+ PE + YDL +P F P +DGE+ F ++ FKP ALV +DFLIRHG + P+ +P+Y Y +H + Sbjct: 1 SGLFGVKQYGVHMNGYTHHPSHGLC--LWIGRRSESKQTYPGKLDNMAAGGLAVGVGIKETLVKEAAEEAGIPACLAERAVPVGTVSYTHENERGIFPECQFVYDLEIPDGFTPHAADGEMQDFYLWPVDKVLEELASGDFKPNCALVTLDFLIRHGLVDPETEPYYHCYVEGIHRTI 176
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Yeast
Match: YJR142W_mRNA (8-oxo-dGTP diphosphatase of the Nudix hydrolase family; converts diphosphates of damaged forms of thiamin to monophosphates; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition [Source:SGD;Acc:S000003903]) HSP 1 Score: 153.68 bits (387), Expect = 6.239e-44 Identity = 94/295 (31.86%), Postives = 150/295 (50.85%), Query Frame = 2 Query: 167 MCTHFFVGSYHVGIILPEVAKYLLQ-----FPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLL----------AYLKSVGTLSL--FFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPF 1000 MCTH +G +L + F + F D +E K + F+ ++ + ++ + ++L+ +K WRNE Y V+V + L VERA + +LG++ YG+H+NGY +D W+ +RS TK T+P ++DN+ GGL + Y + + E EEA++ ++ +YL G +S+ F ++ + EV Y YDL L P +DGEV F E + + FKP ALV++DFLIRHG+ITP+++P+Y MH +LPF Sbjct: 53 MCTH---DGTKIGFVLKFAINEMETVCSEIFEETFQLDESRHELRFKSE----DFDHRNNLIDQLARKMYLESSLSGVKGWRNEKYAVWVNKKPYVL--VERAVAGVLGIITYGIHINGYVLDPKSKKVQFWVPRRSKTKQTWPLMLDNIIAGGLGYPYGIYETVLKESMEEANLEKSVIEDNIKATGSVSYLYFTGDISVTKFNKESDFIVGEVQYVYDLKLSEDIIPKPNDGEVESFNLFSLQETINALRKKEFKPNCALVMVDFLIRHGYITPENEPNYLELVTRMHRRLPF 338
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Nematostella
Match: EDO49598 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFF7]) HSP 1 Score: 211.46 bits (537), Expect = 3.918e-66 Identity = 112/275 (40.73%), Postives = 160/275 (58.18%), Query Frame = 2 Query: 125 KKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVF-ITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPD 946 ++ NN +GSS C F V VG ILP V + ++PD+F + T +++ + + P+L TFEE++ V +V R L+ WR+E Y V + +ER+A+ LLG+ +YGVH+NGY D +G +MW+ +RSL+K TYPG +D + GG+ + + EC EEA + L A K VGT+S FED RG+ PEV + YDL LP SF P SDGEVS F S++K + +K SALV++DFLIRHG ++PD Sbjct: 15 QRLNNFHAAGSSKVHCKPFVVDGITVGTILPNVLTQIRKYPDIFAVIKTTDSDEHVTLVPSLLTFEERTQKVNEVVQEFRKKDLFVTLRGWRDEMYAVGRSFSDRPFFMMERSAACLLGITQYGVHLNGYHRDVNGML-FMWVARRSLSKPTYPGKLDQLVAGGIPCGSNTRETLIKECAEEALIAESLAANAKPVGTVSYVFEDERGVFPEVQFVYDLELPESFTPKASDGEVSDFYYWPISKVKEMIATNEYKFNSALVVLDFLIRHGEVSPD 288
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Nematostella
Match: EDO49616 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFK4]) HSP 1 Score: 200.29 bits (508), Expect = 5.286e-62 Identity = 106/269 (39.41%), Postives = 148/269 (55.02%), Query Frame = 2 Query: 143 IISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETI--IKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITP 943 I SGSS F V VG +LP V +L PDVF +++ ++ + + P+L TFEE++ V V R L+ WR E + V + K+ER+A+ LLGV +YGVH+NGY + + YMWI +RS K T PG +D MA GG+ + + + EC+EEASVP + + VG++S FE +G+ P V + YDL LP F P +DGEVS F ++K + FKP ALV++DFLIRHG I P Sbjct: 5 IASGSSHTESKPFLVEGTRVGTVLPRVMPHLQSHPDVFTIVMNDDGSVEHVTLAPSLKTFEERTKGVNDVMEEFRKNDVFVTLRGWREEEFAVSRAFNERKFFKIERSAACLLGVTQYGVHINGYFRKANSDL-YMWIARRSANKPTGPGKLDQMAAGGITYSSTITETLIKECKEEASVPEHIARHAVPVGSVSFTFETEKGLFPGVQFIYDLCLPEDFTPSVNDGEVSDFYCWPIDKVKEKIITNEFKPNCALVVLDFLIRHGEINP 272
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Medaka
Match: tpk2 (nudix hydrolase 20, chloroplastic [Source:NCBI gene;Acc:101173445]) HSP 1 Score: 207.994 bits (528), Expect = 3.090e-64 Identity = 117/303 (38.61%), Postives = 168/303 (55.45%), Query Frame = 2 Query: 86 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 M + +ER+ ++++ NN +GS C F V VG I P VA L ++P VF T + + +L ++E +S AV +V LR +L L+ WR+E Y V ++ +ERAA++L GV +YGVH+N YTV G MW+ +RS TK TYPGL+DNMA GGL + ECQEEA VP+D + T+S +ED G+ PE + +DL +P+ F P DGEV F + ++K L + FKP SA+V++DFLIRH + PD +PHY + +H L Sbjct: 1 MPSWSERVLHLLNR-MNNFYSTGSCRASCLRFEVDGAQVGWIRPHVASLLSRYPQVF---TAPRGGAVSLCQSLDSYEGRSEAVHEVLLALRQEDSLTCLRGWRDERYSVMPRFSDPPVMWMERAATSLFGVKRYGVHLNAYTVSDGGEVS-MWLARRSSTKQTYPGLLDNMAAGGLAAGVGIKHTLVKECQEEACVPVDTAMTARPAATVSYTYEDEEGVFPESQFVFDLEVPAGFRPRVGDGEVQDFYLLPIEKVKELLATDDFKPNSAMVVLDFLIRHSLVEPDTEPHYQEFVAGLHQTL 298
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Medaka
Match: tpk2 (nudix hydrolase 20, chloroplastic [Source:NCBI gene;Acc:101173445]) HSP 1 Score: 206.453 bits (524), Expect = 1.151e-63 Identity = 114/289 (39.45%), Postives = 159/289 (55.02%), Query Frame = 2 Query: 128 KCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKL 994 + NN +GS C F V VG I P VA L ++P VF T + + +L ++E +S AV +V LR +L L+ WR+E Y V ++ +ERAA++L GV +YGVH+N YTV G MW+ +RS TK TYPGL+DNMA GGL + ECQEEA VP+D + T+S +ED G+ PE + +DL +P+ F P DGEV F + ++K L + FKP SA+V++DFLIRH + PD +PHY + +H L Sbjct: 16 RMNNFYSTGSCRASCLRFEVDGAQVGWIRPHVASLLSRYPQVF---TAPRGGAVSLCQSLDSYEGRSEAVHEVLLALRQEDSLTCLRGWRDERYSVMPRFSDPPVMWMERAATSLFGVKRYGVHLNAYTVSDGGEVS-MWLARRSSTKQTYPGLLDNMAAGGLAAGVGIKHTLVKECQEEACVPVDTAMTARPAATVSYTYEDEEGVFPESQFVFDLEVPAGFRPRVGDGEVQDFYLLPIEKVKELLATDDFKPNSAMVVLDFLIRHSLVEPDTEPHYQEFVAGLHQTL 300
BLAST of Nudix hydrolase domain-containing protein vs. Planmine SMEST
Match: SMESG000064369.1 (SMESG000064369.1) HSP 1 Score: 639.802 bits (1649), Expect = 0.000e+0 Identity = 306/306 (100.00%), Postives = 306/306 (100.00%), Query Frame = 2 Query: 86 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 1003 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD Sbjct: 1 MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLLQFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEYMWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPHYSAYGYWMHSKLPFD 306
BLAST of Nudix hydrolase domain-containing protein vs. Planmine SMEST
Match: SMESG000051615.1 (SMESG000051615.1) HSP 1 Score: 208.764 bits (530), Expect = 3.420e-65 Identity = 110/241 (45.64%), Postives = 146/241 (60.58%), Query Frame = 2 Query: 239 QFPDVFITDTHNNETIIKIKPNLSTFEEKSTAVAKVFSILRDTTNLAALKCWRNEYYGVFVENRSKALLKVERAASTLLGVVKYGVHVNGYTVDKHGNCEY-MWIGQRSLTKLTYPGLMDNMAGGGLNFDYDVLQCARNECQEEASVPLDLLAYLKSVGTLSLFFEDYRGMNPEVMYCYDLILPSSFEPVNSDGEVSHFLKVHCSELKHLAVDERFKPTSALVLIDFLIRHGFITPDDDPH 958 Q+ DVF D + I+ L + EK+ A+ K+FS +RD LK WRNE Y ++ E+ +ER+A+ +LGVV+ GVHV GYT++ N +Y +WIG+RS+ K T+PG +DNM GGG N +Y + + ECQEEA V LL LK G +SL FEDYRG+ PE++YCYDL LP+ F P N DGEV F+ + E+ L FK SALV +DF RHG I PD H Sbjct: 7 QYSDVFRIDDISKTVILN--EELKSSSEKTEAINKIFSEIRDKGTFPFLKKWRNENYAIYSEDLLTYWFDMERSATGILGVVRRGVHVTGYTIN---NGDYFIWIGKRSMNKETHPGKLDNMVGGGCNCNYSIWENVTKECQEEAGVNDGLLKALKPAGCISLMFEDYRGILPEIIYCYDLCLPNDFIPENKDGEVGEFMLMSVEEVGALLGKPCFKYDSALVTLDFYFRHGIIQPDSCEH 242 The following BLAST results are available for this feature:
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 0
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 0
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 0
BLAST of Nudix hydrolase domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of Nudix hydrolase domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 1
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of Nudix hydrolase domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Nudix hydrolase domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 2
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024846 ID=SMED30024846|Name=Nudix hydrolase domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1156bpback to top protein sequence of SMED30024846-orf-1 >SMED30024846-orf-1 ID=SMED30024846-orf-1|Name=SMED30024846-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=307bp MTNINERLWDIVSKKCNNAIISGSSLPMCTHFFVGSYHVGIILPEVAKYLback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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