Lactadherin
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30024840 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of Lactadherin vs. Ensembl Human
Match: MFGE8 (milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:HGNC:7036]) HSP 1 Score: 134.806 bits (338), Expect = 3.844e-34 Identity = 99/334 (29.64%), Postives = 159/334 (47.60%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHILSNK-----GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 EC V PLG+ G+I + QI ASS L+ W ARL NR +W + W+QV+L ++GV+TQG R +++ +F ++YS +G F +I D K F GN + +V N F + A++++ + S H +LR E+LGC+ C LG+ P +I +S S + + +K W A +QW+Q+D+G +T IIT+G + +V Y+V++SN+S NW Y++ + +F GN D++S K N P +AR+ RI P+ W +I +R+ Sbjct: 25 EC--VEPLGLENGNIANSQIAASSVRVTFLGLQHWVPEL----ARL---NRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTG-----------SSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRL 338 HSP 2 Score: 97.8265 bits (242), Expect = 1.652e-21 Identity = 62/156 (39.74%), Postives = 92/156 (58.97%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARLYLE-NRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG-RGDGA-QWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D+QITASS+ K+W + S ARL + N +W A +WLQVDLG+ ++G++TQG R G+ Q+V S+ ++YS D N+ +D GS K+F GN D+ S K N F I AR+++ ++H +LR+E+LGC Sbjct: 189 PLGLKNNSIPDKQITASSS-YKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 343
BLAST of Lactadherin vs. Ensembl Human
Match: MFGE8 (milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:HGNC:7036]) HSP 1 Score: 134.42 bits (337), Expect = 1.386e-33 Identity = 98/334 (29.34%), Postives = 158/334 (47.31%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHILSNK-----GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 E V PLG+ G+I + QI ASS L+ W ARL NR +W + W+QV+L ++GV+TQG R +++ +F ++YS +G F +I D K F GN + +V N F + A++++ + S H +LR E+LGC+ C LG+ P +I +S S + + +K W A +QW+Q+D+G +T IIT+G + +V Y+V++SN+S NW Y++ + +F GN D++S K N P +AR+ RI P+ W +I +R+ Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHW----VPELARL---NRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTG-----------SSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRL 382 HSP 2 Score: 97.4413 bits (241), Expect = 4.435e-21 Identity = 63/159 (39.62%), Postives = 91/159 (57.23%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLE-NRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG-RGDGA-QWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D+QITASS+ L SW S ARL + N +W A +WLQVDLG+ ++G++TQG R G+ Q+V S+ ++YS D N+ +D GS K+F GN D+ S K N F I AR+++ ++H +LR+E+LGC Sbjct: 233 PLGLKNNSIPDKQITASSSYKTWGLHLFSW----NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387
BLAST of Lactadherin vs. Ensembl Human
Match: MFGE8 (milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:HGNC:7036]) HSP 1 Score: 134.42 bits (337), Expect = 1.386e-33 Identity = 98/334 (29.34%), Postives = 158/334 (47.31%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHILSNK-----GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 E V PLG+ G+I + QI ASS L+ W ARL NR +W + W+QV+L ++GV+TQG R +++ +F ++YS +G F +I D K F GN + +V N F + A++++ + S H +LR E+LGC+ C LG+ P +I +S S + + +K W A +QW+Q+D+G +T IIT+G + +V Y+V++SN+S NW Y++ + +F GN D++S K N P +AR+ RI P+ W +I +R+ Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHW----VPELARL---NRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTG-----------SSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRL 382 HSP 2 Score: 97.4413 bits (241), Expect = 4.435e-21 Identity = 63/159 (39.62%), Postives = 91/159 (57.23%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLE-NRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG-RGDGA-QWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D+QITASS+ L SW S ARL + N +W A +WLQVDLG+ ++G++TQG R G+ Q+V S+ ++YS D N+ +D GS K+F GN D+ S K N F I AR+++ ++H +LR+E+LGC Sbjct: 233 PLGLKNNSIPDKQITASSSYKTWGLHLFSW----NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387
BLAST of Lactadherin vs. Ensembl Human
Match: F8 (coagulation factor VIII [Source:HGNC Symbol;Acc:HGNC:3546]) HSP 1 Score: 137.117 bits (344), Expect = 1.344e-32 Identity = 100/337 (29.67%), Postives = 154/337 (45.70%), Query Frame = 3 Query: 114 YEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFH-YIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILS--------------NKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNG--TVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 Y +C T PLGM G I+D QITAS + W ARL Y + +W K + FS W++VDL +I G+ TQG + ++ F+I YS DG + Y + G+ VF GN DS +KHN FN I AR+I+ H + +LR+E++GC C LG+ T + + ++ + + W + N +W+Q+D + +T + T+G YV E+ +S S + W + QNG VF+GN+DS + +N L P + R+ RIHP +W +I +R+ Sbjct: 2036 YSNKCQT--PLGMASGHIRDFQITASG-QYGQWAPKL----ARLHYSGSINAWSTK-EPFS-WIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGM--------ESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLF---------------FQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRM 2340 HSP 2 Score: 90.5077 bits (223), Expect = 6.628e-18 Identity = 58/156 (37.18%), Postives = 84/156 (53.85%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS---TELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ 590 PLGM I D QITASS +W S+ARL+L+ R +W + + EWLQVD ++GV TQG + +V F+IS S DG + + G KVFQGN+DSF+ N + + R+++ H S+ +LR+E+LGC+ Sbjct: 2196 PLGMESKAISDAQITASSYFTNMFATW----SPSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQN-GKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCE 2346
BLAST of Lactadherin vs. Ensembl Human
Match: EDIL3 (EGF like repeats and discoidin domains 3 [Source:HGNC Symbol;Acc:HGNC:3173]) HSP 1 Score: 130.954 bits (328), Expect = 8.438e-32 Identity = 99/329 (30.09%), Postives = 164/329 (49.85%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLG+ G I +QQITASST L+ W ARL N+K +W A W+Q++L + ++GV+TQG R +++ S+ I+YS DG + K VF+GN D+ + N F I+A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W + +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ ++W Y++ + + VF+GN D+++ + N + P AR RI P +W +I +R Sbjct: 150 GPLGIEGGIISNQQITASSTHRALFGLQKWY----PYYARL---NKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQ-----------RKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLR 460 HSP 2 Score: 89.3521 bits (220), Expect = 3.579e-18 Identity = 58/159 (36.48%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVDL ++G++TQG D Q+V S+ ++YS DG ++ +D+ + KVFQGN D+ + + N + I AR I+ +S++G +LR E+LGC Sbjct: 312 PLGMKSGHIQDYQITASSIFRTLNMDMFTW----EPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 466
BLAST of Lactadherin vs. Ensembl Celegans
Match: ddr-1 (Discoidin domain-containing receptor A [Source:UniProtKB/Swiss-Prot;Acc:Q18163]) HSP 1 Score: 58.5362 bits (140), Expect = 1.327e-8 Identity = 54/157 (34.39%), Postives = 75/157 (47.77%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLE-NRKSWCAKFKSFS---EWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHP-SLRVEILGCQ 590 LGM GDI D QITASS+ K + ARL+ E +WC K + S E+LQV L +I+ V TQGR G G ++ +MI Y G+ + K+ G GN D+ + + I A I+F S + +R EI GC+ Sbjct: 29 LGMQNGDIADSQITASSSFDK---QSVGPQNARLHSELASGAWCPKPQINSKSYEFLQVTLNDTFLITSVETQGRYGNGTGREFASHYMIDYLRPGSQWIRYKNRTG-HVYMDGNFDTTTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCK 181
BLAST of Lactadherin vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7]) HSP 1 Score: 53.1434 bits (126), Expect = 6.016e-7 Identity = 50/165 (30.30%), Postives = 78/165 (47.27%), Query Frame = 3 Query: 120 KECNTVGPLGMIQGDIKDQQITASST-ELKSWRDNCKASQARLYLEN-RKSWCAK--FKSFS-EWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYSTDGTN-FHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 +EC+ LGM I+D+QI+ASS+ +L+S AR + E+ +WC K S S EWLQ+ + VI+ V TQGR G G ++ +F I Y N + KDD+ + + N +++ + I R + +RVE+ GC Sbjct: 23 RECS--HQLGMSNRKIRDEQISASSSFDLQS----TGPQHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGC 181
BLAST of Lactadherin vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7]) HSP 1 Score: 49.2914 bits (116), Expect = 9.951e-6 Identity = 45/150 (30.00%), Postives = 71/150 (47.33%), Query Frame = 3 Query: 165 IKDQQITASST-ELKSWRDNCKASQARLYLEN-RKSWCAK--FKSFS-EWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYSTDGTN-FHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 I+D+QI+ASS+ +L+S AR + E+ +WC K S S EWLQ+ + VI+ V TQGR G G ++ +F I Y N + KDD+ + + N +++ + I R + +RVE+ GC Sbjct: 6 IRDEQISASSSFDLQS----TGPQHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGC 151
BLAST of Lactadherin vs. Ensembl Celegans
Match: ddr-2 (Discoidin domain-containing receptor tyrosine kinase B [Source:UniProtKB/Swiss-Prot;Acc:Q95ZV7]) HSP 1 Score: 49.2914 bits (116), Expect = 9.951e-6 Identity = 45/150 (30.00%), Postives = 71/150 (47.33%), Query Frame = 3 Query: 165 IKDQQITASST-ELKSWRDNCKASQARLYLEN-RKSWCAK--FKSFS-EWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYSTDGTN-FHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 I+D+QI+ASS+ +L+S AR + E+ +WC K S S EWLQ+ + VI+ V TQGR G G ++ +F I Y N + KDD+ + + N +++ + I R + +RVE+ GC Sbjct: 6 IRDEQISASSSFDLQS----TGPQHARAHQESGSGAWCPKNQINSLSKEWLQISFSVDTVITSVETQGRFDDGRGMEYATAFKIQYWRPSLNAWASYKDDFELETIPANNDTEHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGC 151
BLAST of Lactadherin vs. Ensembl Fly
Match: Hml (gene:FBgn0029167 transcript:FBtr0333020) HSP 1 Score: 87.8113 bits (216), Expect = 1.857e-17 Identity = 68/309 (22.01%), Postives = 125/309 (40.45%), Query Frame = 3 Query: 237 ARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC------QPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNK----------------------------GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 ARL E R SW ++L+++ GV+ G + +V F I +S DG +HY+ D+ ++F G DS + F I A ++ + +HG ++RVE+L C +P + + P + + + +E G + ++ W ++N++I+ D +P I+ +TKG D +VT Y+V FS W N + +F+ N D+ +E+ ++ + P + ++ +I P W++ I MRI Sbjct: 2107 ARLTKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSHDGIAYHYLVDETEKPQMFNGPLDSRAPVQTLFKIPIEASSLRIYPLKWHGSIAMRVELLICGDKEEPKPVPTVSTILPITERPARLVDLECIDLMGVDE-GKMYQDQVQSSSLWQQPNLGKKLQLLELLKLSTPLAWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDG----WVTGYKVMFSKKKPTW------------NTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRI 2398 HSP 2 Score: 50.447 bits (119), Expect = 6.223e-6 Identity = 27/108 (25.00%), Postives = 56/108 (51.85%), Query Frame = 3 Query: 264 SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 +W S +E+++ D ISG +T+G DG WV + + +S ++ + G ++F+ N D+ + + ++F + I ++IK + + ++R+E LGC Sbjct: 2298 AWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDG--WVTGYKVMFSKKKPTWNTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRIEPLGC 2403
BLAST of Lactadherin vs. Ensembl Fly
Match: Hml (gene:FBgn0029167 transcript:FBtr0075753) HSP 1 Score: 87.8113 bits (216), Expect = 1.890e-17 Identity = 68/309 (22.01%), Postives = 125/309 (40.45%), Query Frame = 3 Query: 237 ARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC------QPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNK----------------------------GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 ARL E R SW ++L+++ GV+ G + +V F I +S DG +HY+ D+ ++F G DS + F I A ++ + +HG ++RVE+L C +P + + P + + + +E G + ++ W ++N++I+ D +P I+ +TKG D +VT Y+V FS W N + +F+ N D+ +E+ ++ + P + ++ +I P W++ I MRI Sbjct: 2108 ARLTKEQPRGSWSPSINDQMQYLELNFAKPEPFYGVVMAGSPEFDNYVTLFKILHSHDGIAYHYLVDETEKPQMFNGPLDSRAPVQTLFKIPIEASSLRIYPLKWHGSIAMRVELLICGDKEEPKPVPTVSTILPITERPARLVDLECIDLMGVDE-GKMYQDQVQSSSLWQQPNLGKKLQLLELLKLSTPLAWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDG----WVTGYKVMFSKKKPTW------------NTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRI 2399 HSP 2 Score: 50.447 bits (119), Expect = 6.438e-6 Identity = 27/108 (25.00%), Postives = 56/108 (51.85%), Query Frame = 3 Query: 264 SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 +W S +E+++ D ISG +T+G DG WV + + +S ++ + G ++F+ N D+ + + ++F + I ++IK + + ++R+E LGC Sbjct: 2299 AWRPLANSQNEFIEFDFLEPRNISGFVTKGGPDG--WVTGYKVMFSKKKPTWNTVLSTDGQARIFEANHDAETERRHHFKNPILTQYIKIVPAYWEKNINMRIEPLGC 2404
BLAST of Lactadherin vs. Ensembl Fly
Match: Nrx-IV (gene:FBgn0013997 transcript:FBtr0075998) HSP 1 Score: 69.3218 bits (168), Expect = 8.771e-12 Identity = 38/119 (31.93%), Postives = 59/119 (49.58%), Query Frame = 3 Query: 702 NKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 N W + N ++ +D+G P ++ I T GR + +VTEY V +S++ + W Y N S P +FKGN D NS N P +A++ RI+P W ++I MR+ Sbjct: 76 NAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDE--FVTEYIVQYSDDGEFWRSYV-NPTSEPQ-----------MFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDRISMRV 180 HSP 2 Score: 61.6178 bits (148), Expect = 2.032e-9 Identity = 36/143 (25.17%), Postives = 70/143 (48.95%), Query Frame = 3 Query: 180 ITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEIL 608 +TA+S+ + D + L +W +++ +L +DLG ++ + T GR ++V +++ YS DG + + ++F+GN D S+ +N F I A++++ + +H S+RVE+ GC E L Sbjct: 57 LTATSSLTERGPDKAR-------LNGNAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDEFVTEYIVQYSDDGEFWRSYVNPTSEPQMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDRISMRVELYGCDYISENL 192
BLAST of Lactadherin vs. Ensembl Fly
Match: Nrx-IV (gene:FBgn0013997 transcript:FBtr0075999) HSP 1 Score: 68.9366 bits (167), Expect = 1.311e-11 Identity = 43/143 (30.07%), Postives = 70/143 (48.95%), Query Frame = 3 Query: 180 ITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEIL 608 +TA+S+ + D + L SW AK F + L +DLG ++ + QGR ++V + ISY F K+ G+ K+F+GN D S+ +N F I A++++ + +H S+RVE+ GC E L Sbjct: 57 LTATSSLTERGPDKAR-------LNAGTSWSAKNSDFDQRLIIDLGVVRNVTHIALQGRPHSNEYVTEYTISYGITDLEFADYKEPGGNVKMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDRISMRVELYGCDYISENL 192 HSP 2 Score: 64.3142 bits (155), Expect = 3.129e-10 Identity = 41/116 (35.34%), Postives = 57/116 (49.14%), Query Frame = 3 Query: 711 WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 W AK + +Q + ID+G +T I +GR S YVTEY +S+ + YKE NV M FKGN D NS N P +A++ RI+P W ++I MR+ Sbjct: 79 WSAKNSDFDQRLIIDLGVVRNVTHIALQGRPHSNE--YVTEYTISYGITDLEFADYKEPG----GNVKM--------FKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDRISMRV 180
BLAST of Lactadherin vs. Ensembl Fly
Match: Ddr (gene:FBgn0053531 transcript:FBtr0340169) HSP 1 Score: 67.0106 bits (162), Expect = 1.726e-11 Identity = 50/156 (32.05%), Postives = 75/156 (48.08%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-SWCAKF---KSFSEWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYS-FHGHPSLRVEILGC 587 LGM G I D QITASS N ARL ++N +WC K + +E+LQVDL ++S + TQGR G G ++ +++I Y G ++V GN +++S N + A ++ + YS + LR EI+GC Sbjct: 110 LGMESGAIADFQITASSAHDMG---NVGPQHARLKIDNNGGAWCPKHMVSRGLTEYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTEAYVIEYWRPGLKKWIRWRSLQGKEVLPGNINTYSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGC 262
BLAST of Lactadherin vs. Ensembl Zebrafish
Match: edil3a (EGF-like repeats and discoidin I-like domains 3a [Source:ZFIN;Acc:ZDB-GENE-060503-366]) HSP 1 Score: 135.191 bits (339), Expect = 7.254e-34 Identity = 102/329 (31.00%), Postives = 164/329 (49.85%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQK-VFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + K + +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E +G + Y SS + E L +G W + +++QW+Q+D+ +P+ IT IIT+G D H +V Y+V++SNN + W Y++ + + VF+GN D+++ + N + P ARF RI P +W +I +R Sbjct: 93 GPLGMEGGIISNQQITASSTHRALFGLQKWY----PYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYKVKGTDEDIIFRGNIDNNTPFANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELSGCSEPMGMKSGHIQDYQITASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQ-----------KKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLR 403 HSP 2 Score: 89.3521 bits (220), Expect = 1.781e-18 Identity = 56/159 (35.22%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVD+ I+G++TQG D Q+V S+ ++YS +G + +D+ + KVFQGN D+ + + N + I ARF++ +S++G +LR E+LGC Sbjct: 255 PMGMKSGHIQDYQITASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQKKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLRAELLGC 409
BLAST of Lactadherin vs. Ensembl Zebrafish
Match: edil3a (EGF-like repeats and discoidin I-like domains 3a [Source:ZFIN;Acc:ZDB-GENE-060503-366]) HSP 1 Score: 135.576 bits (340), Expect = 7.483e-34 Identity = 102/329 (31.00%), Postives = 164/329 (49.85%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQK-VFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + K + +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E +G + Y SS + E L +G W + +++QW+Q+D+ +P+ IT IIT+G D H +V Y+V++SNN + W Y++ + + VF+GN D+++ + N + P ARF RI P +W +I +R Sbjct: 116 GPLGMEGGIISNQQITASSTHRALFGLQKWY----PYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYKVKGTDEDIIFRGNIDNNTPFANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELSGCSEPMGMKSGHIQDYQITASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQ-----------KKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLR 426 HSP 2 Score: 89.3521 bits (220), Expect = 2.091e-18 Identity = 56/159 (35.22%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVD+ I+G++TQG D Q+V S+ ++YS +G + +D+ + KVFQGN D+ + + N + I ARF++ +S++G +LR E+LGC Sbjct: 278 PMGMKSGHIQDYQITASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQKKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLRAELLGC 432
BLAST of Lactadherin vs. Ensembl Zebrafish
Match: edil3a (EGF-like repeats and discoidin I-like domains 3a [Source:ZFIN;Acc:ZDB-GENE-060503-366]) HSP 1 Score: 135.191 bits (339), Expect = 8.175e-34 Identity = 102/329 (31.00%), Postives = 164/329 (49.85%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQK-VFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + K + +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E +G + Y SS + E L +G W + +++QW+Q+D+ +P+ IT IIT+G D H +V Y+V++SNN + W Y++ + + VF+GN D+++ + N + P ARF RI P +W +I +R Sbjct: 106 GPLGMEGGIISNQQITASSTHRALFGLQKWY----PYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYKVKGTDEDIIFRGNIDNNTPFANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELSGCSEPMGMKSGHIQDYQITASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQ-----------KKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLR 416 HSP 2 Score: 88.9669 bits (219), Expect = 2.163e-18 Identity = 56/159 (35.22%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVD+ I+G++TQG D Q+V S+ ++YS +G + +D+ + KVFQGN D+ + + N + I ARF++ +S++G +LR E+LGC Sbjct: 268 PMGMKSGHIQDYQITASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTSGHSDQSQWLQVDMLRPTKITGIITQGAKDFGHVQFVGSYKVAYSNNGERWLIYQDEKQKKDKVFQGNFDNDTHRKNVIDPPIYARFVRILPWSWYGRITLRAELLGC 422
BLAST of Lactadherin vs. Ensembl Zebrafish
Match: f8 (coagulation factor VIII, procoagulant component [Source:ZFIN;Acc:ZDB-GENE-090629-2]) HSP 1 Score: 136.346 bits (342), Expect = 1.367e-32 Identity = 103/349 (29.51%), Postives = 154/349 (44.13%), Query Frame = 3 Query: 63 LLSCVICVASVILIDAD---YEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG----RGDGAQWVVSFMISYSTDGTNFH-YIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHR---TCTEEYGHILSN---KGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 L+ C I + + A Y +CN P+GM I ++QITAS + + K ARL L +W S + WLQVDL ++ G+ TQG G + + + ISYS D N+ Y + F GN D +K N F+ I R+I+ H +F P+LR+E+LGC C LG+ SS S ++ + + + I W K N ++W+Q+D +T +IT+G P VTE+ VS SN+ +W E + +F+GN D+N E +N P RF R+HP W I +R+ Sbjct: 1047 LIECTIGEHQLAGMRAKLLVYNPQCNQ--PIGMQSRWITNKQITASD-----YYGDWKPELARLELTGSINAWMGS--SPNSWLQVDLLRPMILHGIQTQGAKTSMGLSEFFTILYSISYSNDQENWSVYRGNSTKPYYTFNGNMDGSRIKENLFSPPIVGRYIRIHPLTFQKQPTLRIELLGCDLNSCSLPLGMERRSIPNSSISASSFLNKWLLSWSPDLARIHQEGRANAWRPKSNNPHEWLQVDFASVKRVTGLITQGARSVLKPMMVTEFTVSVSNDGHSWSSVTEQG-----------TDSEQIFEGNSDNNEETLNIFDPPLFTRFIRVHPKGWVNDIALRL 1375 HSP 2 Score: 77.7962 bits (190), Expect = 3.017e-14 Identity = 50/153 (32.68%), Postives = 79/153 (51.63%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM + I + I+ASS L W + AR++ E R +W K + EWLQVD + ++G++TQG V F +S S DG ++ + + S+++F+GN D+ N F+ + RFI+ H + +LR+E LGC Sbjct: 1229 PLGMERRSIPNSSISASSF-LNKWLLSWSPDLARIHQEGRANAWRPKSNNPHEWLQVDFASVKRVTGLITQGARSVLKPMMVTEFTVSVSNDGHSWSSVTEQGTDSEQIFEGNSDNNEETLNIFDPPLFTRFIRVHPKGWVNDIALRLEFLGC 1380
BLAST of Lactadherin vs. Ensembl Zebrafish
Match: edil3b (EGF-like repeats and discoidin I-like domains 3b [Source:ZFIN;Acc:ZDB-GENE-090312-42]) HSP 1 Score: 131.339 bits (329), Expect = 1.838e-32 Identity = 99/330 (30.00%), Postives = 160/330 (48.48%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++ ++TQG R ++V SF ++YS DG + K +F GN D+ S N F+ I A++I+ + H +LR+E+LGC+ C E +G + Y SS + + L +G W + +++QW+QID+ P+ +T IIT+G D H +V ++++FSN+ + W Y++ + +F+GN D+ + + N + P ARF RI P +W +I +R+ Sbjct: 97 GPLGMEGGIISNQQITASSTHRALFGLQKWF----PYFARL---NKKGLVNAWSAAEGDRYPWIQINLLRRMRVTALITQGAKRIGSPEYVKSFKVAYSEDGKAWSLFKVKGTDEDMIFTGNTDNSSPSVNSFSPPIEAQYIRVYPQICRKHCTLRMELLGCELTGCSEPMGMKTGHIQDYQLSSSSVFQTLSMDMFSWDPSKARLDKQGKVNAWTSAHNDQSQWLQIDLLIPTKVTGIITQGAKDFGHVQFVGSFKLAFSNDGEKWIIYQDEKQ-----------HKDKIFQGNFDNETHRKNVIDPPIYARFVRILPWSWYGRITVRM 408 HSP 2 Score: 87.4261 bits (215), Expect = 8.034e-18 Identity = 53/159 (33.33%), Postives = 93/159 (58.49%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM G I+D Q+++SS ++ SW S+ARL + + +W + S+WLQ+DL ++G++TQG D Q+V SF +++S DG + +D+ + K+FQGN D+ + + N + I ARF++ +S++G ++R+E+LGC Sbjct: 259 PMGMKTGHIQDYQLSSSSVFQTLSMDMFSW----DPSKARLDKQGKVNAWTSAHNDQSQWLQIDLLIPTKVTGIITQGAKDFGHVQFVGSFKLAFSNDGEKWIIYQDEKQHKDKIFQGNFDNETHRKNVIDPPIYARFVRILPWSWYGRITVRMELLGC 413
BLAST of Lactadherin vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:Xenbase;Acc:XB-GENE-483879]) HSP 1 Score: 142.51 bits (358), Expect = 2.337e-36 Identity = 104/331 (31.42%), Postives = 155/331 (46.83%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---------GHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 E + LGM I D QIT+SS L+ W N ARL + +W A W+QV+L E +SGV+TQG R A++V F ++YS DG F + K + G K+F GN D+ K N F+ I ARFI+ + + +LR E+ GC+P C + LG+ + + I W A + N+ QW+QID+ P I+ IIT+G D + YV ++V++S++ W YK++ + +F GN D+ S K N PF ARF R+ P +W E+I +R+ Sbjct: 87 EISCANALGMEGRAISDAQITSSSMYHGFLGLQRWGPN----LARLNNKGMVNAWTANSLDQHPWIQVNLLREMRVSGVITQGASRMGTAEYVKEFKVAYSVDGHEFTFYKSE-GKDKLFPGNIDNDGRKANLFSPPISARFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSVYKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSR-----------TKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRM 401 HSP 2 Score: 90.5077 bits (223), Expect = 9.903e-19 Identity = 67/186 (36.02%), Postives = 96/186 (51.61%), Query Frame = 3 Query: 54 RFLLLSCVICVASVILIDADYEKECNTVG-PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 RF+ + V C + L Y E + PLGM I D+QI ASS K+W + ARL + +W A + +WLQ+DL ISG++TQG D Q+V SF ++YS DG + KD + K+F GN D++S K N F+ ARF++ S+H +LR+E+LGC Sbjct: 222 RFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSV-YKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSRTKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRMELLGC 406
BLAST of Lactadherin vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:Xenbase;Acc:XB-GENE-483879]) HSP 1 Score: 142.895 bits (359), Expect = 2.869e-36 Identity = 104/331 (31.42%), Postives = 155/331 (46.83%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---------GHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 E + LGM I D QIT+SS L+ W N ARL + +W A W+QV+L E +SGV+TQG R A++V F ++YS DG F + K + G K+F GN D+ K N F+ I ARFI+ + + +LR E+ GC+P C + LG+ + + I W A + N+ QW+QID+ P I+ IIT+G D + YV ++V++S++ W YK++ + +F GN D+ S K N PF ARF R+ P +W E+I +R+ Sbjct: 110 EISCANALGMEGRAISDAQITSSSMYHGFLGLQRWGPN----LARLNNKGMVNAWTANSLDQHPWIQVNLLREMRVSGVITQGASRMGTAEYVKEFKVAYSVDGHEFTFYKSE-GKDKLFPGNIDNDGRKANLFSPPISARFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSVYKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSR-----------TKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRM 424 HSP 2 Score: 90.1225 bits (222), Expect = 1.584e-18 Identity = 67/186 (36.02%), Postives = 96/186 (51.61%), Query Frame = 3 Query: 54 RFLLLSCVICVASVILIDADYEKECNTVG-PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 RF+ + V C + L Y E + PLGM I D+QI ASS K+W + ARL + +W A + +WLQ+DL ISG++TQG D Q+V SF ++YS DG + KD + K+F GN D++S K N F+ ARF++ S+H +LR+E+LGC Sbjct: 245 RFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSV-YKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSRTKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRMELLGC 429
BLAST of Lactadherin vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:Xenbase;Acc:XB-GENE-483879]) HSP 1 Score: 142.124 bits (357), Expect = 5.251e-36 Identity = 106/334 (31.74%), Postives = 156/334 (46.71%), Query Frame = 3 Query: 120 KECN--TVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---------GHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K CN LGM I D QIT+SS L+ W N ARL + +W A W+QV+L E +SGV+TQG R A++V F ++YS DG F + K + G K+F GN D+ K N F+ I ARFI+ + + +LR E+ GC+P C + LG+ + + I W A + N+ QW+QID+ P I+ IIT+G D + YV ++V++S++ W YK++ + +F GN D+ S K N PF ARF R+ P +W E+I +R+ Sbjct: 108 KVCNIRCANALGMEGRAISDAQITSSSMYHGFLGLQRWGPN----LARLNNKGMVNAWTANSLDQHPWIQVNLLREMRVSGVITQGASRMGTAEYVKEFKVAYSVDGHEFTFYKSE-GKDKLFPGNIDNDGRKANLFSPPISARFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSVYKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSR-----------TKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRM 425 HSP 2 Score: 90.8929 bits (224), Expect = 9.286e-19 Identity = 67/186 (36.02%), Postives = 96/186 (51.61%), Query Frame = 3 Query: 54 RFLLLSCVICVASVILIDADYEKECNTVG-PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 RF+ + V C + L Y E + PLGM I D+QI ASS K+W + ARL + +W A + +WLQ+DL ISG++TQG D Q+V SF ++YS DG + KD + K+F GN D++S K N F+ ARF++ S+H +LR+E+LGC Sbjct: 246 RFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSV-YKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSRTKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRMELLGC 430
BLAST of Lactadherin vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:Xenbase;Acc:XB-GENE-483879]) HSP 1 Score: 142.51 bits (358), Expect = 8.545e-36 Identity = 106/334 (31.74%), Postives = 156/334 (46.71%), Query Frame = 3 Query: 120 KECN--TVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---------GHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K CN LGM I D QIT+SS L+ W N ARL + +W A W+QV+L E +SGV+TQG R A++V F ++YS DG F + K + G K+F GN D+ K N F+ I ARFI+ + + +LR E+ GC+P C + LG+ + + I W A + N+ QW+QID+ P I+ IIT+G D + YV ++V++S++ W YK++ + +F GN D+ S K N PF ARF R+ P +W E+I +R+ Sbjct: 145 KVCNIRCANALGMEGRAISDAQITSSSMYHGFLGLQRWGPN----LARLNNKGMVNAWTANSLDQHPWIQVNLLREMRVSGVITQGASRMGTAEYVKEFKVAYSVDGHEFTFYKSE-GKDKLFPGNIDNDGRKANLFSPPISARFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSVYKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSR-----------TKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRM 462 HSP 2 Score: 89.7373 bits (221), Expect = 2.467e-18 Identity = 67/186 (36.02%), Postives = 96/186 (51.61%), Query Frame = 3 Query: 54 RFLLLSCVICVASVILIDADYEKECNTVG-PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 RF+ + V C + L Y E + PLGM I D+QI ASS K+W + ARL + +W A + +WLQ+DL ISG++TQG D Q+V SF ++YS DG + KD + K+F GN D++S K N F+ ARF++ S+H +LR+E+LGC Sbjct: 283 RFIRIYPVTCRVACTLRFELYGCEPSGCSDPLGMKTQVISDKQIKASSV-YKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSRTKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRMELLGC 467
BLAST of Lactadherin vs. Ensembl Xenopus
Match: mef2d (myocyte enhancer factor 2D [Source:Xenbase;Acc:XB-GENE-483879]) HSP 1 Score: 140.584 bits (353), Expect = 2.066e-35 Identity = 106/340 (31.18%), Postives = 156/340 (45.88%), Query Frame = 3 Query: 120 KECN--TVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--------CKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---------GHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K CN LGM I D QIT+SS L+ W N ARL + +W A W+QV+L E +SGV+TQG R A++V F ++YS DG F + K + G K+F GN D+ K N F+ I ARFI+ + + +LR E+ GC+P C + LG+ + + I W A + N+ QW+QID+ P I+ IIT+G D + YV ++V++S++ W YK++ + +F GN D+ S K N PF ARF R+ P +W E+I +R+ Sbjct: 104 KVCNIRCANALGMEGRAISDAQITSSSMYHGFLGLQRWGPN----LARLNNKGMVNAWTANSLDQHPWIQVNLLREMRVSGVITQGASRMGTAEYVKEFKVAYSVDGHEFTFYKSE-GKDKLFPGNIDNDGRKANLFSPPISARFIRIYPVTCRVACTLRFELYGCEPSVYFNMVGCSDPLGMKTQVISDKQIKASSVYKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSR-----------TKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRM 427 HSP 2 Score: 90.8929 bits (224), Expect = 1.023e-18 Identity = 68/190 (35.79%), Postives = 97/190 (51.05%), Query Frame = 3 Query: 51 MRFLLLSC-VICVASVILIDADYEKECNTVG---PLGMIQGDIKDQQITASSTELKSWRDNC---KASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 +R ++C V C L + N VG PLGM I D+QI ASS K+W + ARL + +W A + +WLQ+DL ISG++TQG D Q+V SF ++YS DG + KD + K+F GN D++S K N F+ ARF++ S+H +LR+E+LGC Sbjct: 244 IRIYPVTCRVACTLRFELYGCEPSVYFNMVGCSDPLGMKTQVISDKQIKASSV-YKTWGIDAFTWHPHYARLDKIGKTNAWTALENNQEQWLQIDLRIPKKISGIITQGAKDFGNIQYVESFKVAYSDDGNTWKIYKDSRTKADKIFLGNNDNYSHKKNLFDVPFSARFVRVLPQSWHERITLRMELLGC 432
BLAST of Lactadherin vs. Ensembl Mouse
Match: Mfge8 (milk fat globule-EGF factor 8 protein [Source:MGI Symbol;Acc:MGI:102768]) HSP 1 Score: 174.481 bits (441), Expect = 1.180e-47 Identity = 121/347 (34.87%), Postives = 177/347 (51.01%), Query Frame = 3 Query: 78 ICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 IC V E C+T LGM G I D QI+ASS L+ W ARLY +W A W+QV+L + +SGVMTQG R A+++ +F ++YS DG F +I+D+ G K F GN D+ S+K N FN + A++IK + S H +LR E+LGC+ C E LG+ P ++ +S S R Y H+ L N+G W A+ + +W+Q+D+G +T IIT+G D H YV Y+V+ S++ W Y+E S VF+GN D+NS K N +PF+AR+ R+ P++W +I +R+ Sbjct: 95 ICQCPVGYSGIHCETGCST--QLGMEGGAIADSQISASSVYMGFMGLQRW----GPELARLYRTGIVNAWTASNYDSKPWIQVNLLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRKFEFIQDESGGDKEFLGNLDNNSLKVNMFNPTLEAQYIKLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQMSASSSYKTWNLRA-FGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGSS-------------KVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRL 421 HSP 2 Score: 96.6709 bits (239), Expect = 9.034e-21 Identity = 60/155 (38.71%), Postives = 91/155 (58.71%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENR---KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D Q++ASS+ K+W L L+N+ +W A+ S EWLQVDLGT+ ++G++TQG D Q+V S+ +++S DG + + ++ GS KVFQGN D+ S K N F AR+++ S+H +LR+E+LGC Sbjct: 274 PLGLKNNTIPDSQMSASSS-YKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWT-VYEEQGSSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRLELLGC 426
BLAST of Lactadherin vs. Ensembl Mouse
Match: Mfge8 (milk fat globule-EGF factor 8 protein [Source:MGI Symbol;Acc:MGI:102768]) HSP 1 Score: 172.94 bits (437), Expect = 1.036e-46 Identity = 115/325 (35.38%), Postives = 170/325 (52.31%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 LGM G I D QI+ASS L+ W ARLY +W A W+QV+L + +SGVMTQG R A+++ +F ++YS DG F +I+D+ G K F GN D+ S+K N FN + A++IK + S H +LR E+LGC+ C E LG+ P ++ +S S R Y H+ L N+G W A+ + +W+Q+D+G +T IIT+G D H YV Y+V+ S++ W Y+E S VF+GN D+NS K N +PF+AR+ R+ P++W +I +R+ Sbjct: 152 LGMEGGAIADSQISASSVYMGFMGLQRW----GPELARLYRTGIVNAWTASNYDSKPWIQVNLLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRKFEFIQDESGGDKEFLGNLDNNSLKVNMFNPTLEAQYIKLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQMSASSSYKTWNLRA-FGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGSS-------------KVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRL 458 HSP 2 Score: 97.4413 bits (241), Expect = 6.678e-21 Identity = 60/155 (38.71%), Postives = 91/155 (58.71%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENR---KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D Q++ASS+ K+W L L+N+ +W A+ S EWLQVDLGT+ ++G++TQG D Q+V S+ +++S DG + + ++ GS KVFQGN D+ S K N F AR+++ S+H +LR+E+LGC Sbjct: 311 PLGLKNNTIPDSQMSASSS-YKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWT-VYEEQGSSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRLELLGC 463
BLAST of Lactadherin vs. Ensembl Mouse
Match: Edil3 (EGF-like repeats and discoidin I-like domains 3 [Source:MGI Symbol;Acc:MGI:1329025]) HSP 1 Score: 133.265 bits (334), Expect = 9.789e-33 Identity = 99/329 (30.09%), Postives = 166/329 (50.46%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLG+ G I +QQITASST L+ W ARL N+K +W A W+Q++L + ++GV+TQG R +++ S+ I+YS DG + K + VF+GN D+ + N F I+A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W + +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ ++W +++ + + VF+GN D+++ + N + P ARF RI P +W +I +R Sbjct: 160 GPLGIEGGIISNQQITASSTHRALFGLQKWY----PYYARL---NKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSVFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQ-----------RKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLR 470 HSP 2 Score: 92.0485 bits (227), Expect = 3.454e-19 Identity = 59/159 (37.11%), Postives = 93/159 (58.49%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVDL ++G++TQG D Q+V S+ ++YS DG ++ +D+ + KVFQGN D+ + + N + I ARFI+ +S++G +LR E+LGC Sbjct: 322 PLGMKSGHIQDYQITASSVFRTLNMDMFTW----EPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLRSELLGC 476
BLAST of Lactadherin vs. Ensembl Mouse
Match: Edil3 (EGF-like repeats and discoidin I-like domains 3 [Source:MGI Symbol;Acc:MGI:1329025]) HSP 1 Score: 132.88 bits (333), Expect = 1.117e-32 Identity = 99/329 (30.09%), Postives = 166/329 (50.46%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLG+ G I +QQITASST L+ W ARL N+K +W A W+Q++L + ++GV+TQG R +++ S+ I+YS DG + K + VF+GN D+ + N F I+A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W + +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ ++W +++ + + VF+GN D+++ + N + P ARF RI P +W +I +R Sbjct: 150 GPLGIEGGIISNQQITASSTHRALFGLQKWY----PYYARL---NKKGLINAWTAAENDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEEMVFRGNVDNNTPYANSFTPPIKAQYVRLYPQICRRHCTLRMELLGCELSGCSEPLGMKSGHIQDYQITASSVFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQ-----------RKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLR 460 HSP 2 Score: 92.0485 bits (227), Expect = 3.856e-19 Identity = 59/159 (37.11%), Postives = 93/159 (58.49%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D QITASS ++ +W + +ARL + + +W + S+WLQVDL ++G++TQG D Q+V S+ ++YS DG ++ +D+ + KVFQGN D+ + + N + I ARFI+ +S++G +LR E+LGC Sbjct: 312 PLGMKSGHIQDYQITASSVFRTLNMDMFTW----EPRKARLDKQGKVNAWTSGHNDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWMVHQDEKQRKDKVFQGNFDNDTHRKNVIDPPIYARFIRILPWSWYGRITLRSELLGC 466
BLAST of Lactadherin vs. Ensembl Mouse
Match: F8 (coagulation factor VIII [Source:MGI Symbol;Acc:MGI:88383]) HSP 1 Score: 134.806 bits (338), Expect = 5.226e-32 Identity = 99/335 (29.55%), Postives = 153/335 (45.67%), Query Frame = 3 Query: 114 YEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTN-FHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILS--------------NKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 Y K+C PLGM G I+D QITAS W N ARL Y + +W K + FS W++VDL ++ G+ TQG + ++ F+I YS DG Y + G+ VF GN DS +KHN FN I AR+I+ H +LR+E++GC C LG+ T + + ++ + W + + QW+Q+D+ + +T IIT+G +V E+ +S S + +W N + VF+GN+DS++ +N L P + R+ RIHP W+ +I +R+ Sbjct: 2004 YSKQCQI--PLGMASGSIRDFQITASG-HYGQWAPNL----ARLHYSGSINAWSTK-EPFS-WIKVDLLAPMIVHGIKTQGARQKFSSLYISQFIIMYSLDGKKWLSYQGNSTGTLMVFFGNVDSSGIKHNSFNPPIIARYIRLHPTHSSIRSTLRMELMGCDLNSCSIPLGM--------ESKVISDTQITASSYFTNMFATWSPSQARLHLQGRTNAWRPQVNDPKQWLQVDLQKTMKVTGIITQGVKSLFTSMFVKEFLISSSQDGHHWTQILYNGKV-------------KVFQGNQDSSTPMMNSLDPPLLTRYLRIHPQIWEHQIALRL 2308 HSP 2 Score: 90.1225 bits (222), Expect = 5.578e-18 Identity = 64/189 (33.86%), Postives = 94/189 (49.74%), Query Frame = 3 Query: 45 SNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASS---TELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDY-GSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ 590 S +R L+ C + S+ PLGM I D QITASS +W SQARL+L+ R +W + +WLQVDL ++G++TQG + +V F+IS S DG H+ + Y G KVFQGN+DS + N + + R+++ H + +LR+EILGC+ Sbjct: 2147 STLRMELMGCDLNSCSI---------------PLGMESKVISDTQITASSYFTNMFATW----SPSQARLHLQGRTNAWRPQVNDPKQWLQVDLQKTMKVTGIITQGVKSLFTSMFVKEFLISSSQDG--HHWTQILYNGKVKVFQGNQDSSTPMMNSLDPPLLTRYLRIHPQIWEHQIALRLEILGCE 2314
BLAST of Lactadherin vs. UniProt/SwissProt
Match: sp|P21956|MFGM_MOUSE (Lactadherin OS=Mus musculus OX=10090 GN=Mfge8 PE=1 SV=3) HSP 1 Score: 172.94 bits (437), Expect = 7.247e-46 Identity = 115/325 (35.38%), Postives = 170/325 (52.31%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 LGM G I D QI+ASS L+ W ARLY +W A W+QV+L + +SGVMTQG R A+++ +F ++YS DG F +I+D+ G K F GN D+ S+K N FN + A++IK + S H +LR E+LGC+ C E LG+ P ++ +S S R Y H+ L N+G W A+ + +W+Q+D+G +T IIT+G D H YV Y+V+ S++ W Y+E S VF+GN D+NS K N +PF+AR+ R+ P++W +I +R+ Sbjct: 152 LGMEGGAIADSQISASSVYMGFMGLQRW----GPELARLYRTGIVNAWTASNYDSKPWIQVNLLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRKFEFIQDESGGDKEFLGNLDNNSLKVNMFNPTLEAQYIKLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQMSASSSYKTWNLRA-FGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGSS-------------KVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRL 458 HSP 2 Score: 97.4413 bits (241), Expect = 4.671e-20 Identity = 60/155 (38.71%), Postives = 91/155 (58.71%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENR---KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D Q++ASS+ K+W L L+N+ +W A+ S EWLQVDLGT+ ++G++TQG D Q+V S+ +++S DG + + ++ GS KVFQGN D+ S K N F AR+++ S+H +LR+E+LGC Sbjct: 311 PLGLKNNTIPDSQMSASSS-YKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQRQVTGIITQGARDFGHIQYVASYKVAHSDDGVQWT-VYEEQGSSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPVSWHNRITLRLELLGC 463
BLAST of Lactadherin vs. UniProt/SwissProt
Match: sp|P70490|MFGM_RAT (Lactadherin OS=Rattus norvegicus OX=10116 GN=Mfge8 PE=2 SV=1) HSP 1 Score: 169.088 bits (427), Expect = 8.857e-45 Identity = 120/348 (34.48%), Postives = 178/348 (51.15%), Query Frame = 3 Query: 78 ICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGS-QKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCTEEYGHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 IC V E C+T LG+ G I D QI+ASS L+ W ARLY +W A W+QVD + +SGVMTQG R A+++ +F ++YS DG F +I+D+ G+ K F GN+D+ S+K N FN + A++I+ + S H +LR E+LGC+ C E LG+ P +I +S S R Y H+ L N+G W A+ + +W+Q+D+G +T IIT+G D H YV Y+V+ S++ W Y+E S VF+GN D+NS K N +PF+AR+ R+ P++W +I +R+ Sbjct: 95 ICQCPVGYSGIHCELGCST--KLGLEGGAIADSQISASSVYMGFMGLQRW----GPELARLYRTGIVNAWTASSYDSKPWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRA-FGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGTS-------------KVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRL 422 HSP 2 Score: 97.8265 bits (242), Expect = 2.082e-20 Identity = 61/155 (39.35%), Postives = 91/155 (58.71%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENR---KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I D QITASS+ K+W L L+N+ +W A+ S EWLQVDLGT+ ++G++TQG D Q+V S+ +++S DG + + ++ G+ KVFQGN D+ S K N F AR+++ S+H +LR+E+LGC Sbjct: 275 PLGLKNNTIPDSQITASSS-YKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHSDDGVQWT-VYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRLELLGC 427
BLAST of Lactadherin vs. UniProt/SwissProt
Match: sp|P79385|MFGM_PIG (Lactadherin OS=Sus scrofa OX=9823 GN=MFGE8 PE=1 SV=2) HSP 1 Score: 151.369 bits (381), Expect = 1.121e-38 Identity = 105/332 (31.63%), Postives = 163/332 (49.10%), Query Frame = 3 Query: 126 CNTVGPLGMIQGDIKDQQITASSTEL-----KSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKD-DYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEE------YGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 CN PLGM G I D QI+ASS L + W ARL+ +W A + W+QV+L ++GV+TQG R A+++ +F ++YSTDG F +I+ + K+F GN D+ +K N F + ++++ H +LR E+LGC+ C E LG+ I + +RT + L N+G W A+ + ++W+QID+G +T IIT+G D H YV Y+V++S++ +W Y++ G +F GN D+NS K N PF+ RF RI P+ W +I +R+ Sbjct: 91 CNA--PLGMETGAIADFQISASSMHLGFMGLQRW----APELARLHRAGIVNAWTASNYDRNPWIQVNLLRRMRVTGVVTQGASRAGSAEYMKTFKVAYSTDGRKFQFIQGAEESGDKIFMGNLDNSGLKVNLFEVPLEVQYVRLVPIICHRGCTLRFELLGCELSGCAEPLGL-KDNTIPNKQITASSFYRTWGLSAFSWYPFYARLDNQGKFNAWTAQSNSASEWLQIDLGSQRRVTGIITQGARDFGHIQYVAAYKVAYSDDGVSWTEYRDQGA-----------LEGKIFPGNLDNNSHKKNMFETPFLTRFVRILPVAWHNRITLRV 404 HSP 2 Score: 88.9669 bits (219), Expect = 1.516e-17 Identity = 56/156 (35.90%), Postives = 91/156 (58.33%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKA---SQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I ++QITASS ++W + + ARL + + +W A+ S SEWLQ+DLG++ ++G++TQG D Q+V ++ ++YS DG ++ +D + K+F GN D+ S K N F RF++ ++H +LRVE+LGC Sbjct: 255 PLGLKDNTIPNKQITASSF-YRTWGLSAFSWYPFYARLDNQGKFNAWTAQSNSASEWLQIDLGSQRRVTGIITQGARDFGHIQYVAAYKVAYSDDGVSWTEYRDQGALEGKIFPGNLDNNSHKKNMFETPFLTRFVRILPVAWHNRITLRVELLGC 409
BLAST of Lactadherin vs. UniProt/SwissProt
Match: sp|Q95114|MFGM_BOVIN (Lactadherin OS=Bos taurus OX=9913 GN=MFGE8 PE=1 SV=2) HSP 1 Score: 149.443 bits (376), Expect = 8.525e-38 Identity = 107/347 (30.84%), Postives = 168/347 (48.41%), Query Frame = 3 Query: 78 ICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTEL-----KSWRDNCKASQARLYLEN-RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGV----FPYXXXXXXXXXXXXXHRTCT-EEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 IC + + E C + PLGM G I D QI+ASS L + W ARL+ +W + + W+QV+L + ++GV+TQG R A+++ +F ++YSTDG F +I+ K+F GN ++ +K N F+ + ++++ H +LR E+LGC+ C E LG+ P +I +S + Y L N+G W A+ + ++W+QID+G +T IIT+G D H YV Y+V++ ++ W YK+ S +F GN D+NS K N PF ARF RI P+ W +I +R+ Sbjct: 93 ICKCPLGYVGIHCETTCTS--PLGMQTGAIADSQISASSMHLGFMGLQRW----APELARLHQTGIVNAWTSGNYDKNPWIQVNLMRKMWVTGVVTQGASRAGSAEYLKTFKVAYSTDGRQFQFIQVAGRSGDKIFIGNVNNSGLKINLFDTPLETQYVRLVPIICHRGCTLRFELLGCELNGCTEPLGLKDNTIPNKQITASSYYKTWGLSAFSWFPYYARLDNQGKFNAWTAQTNSASEWLQIDLGSQKRVTGIITQGARDFGHIQYVAAYRVAYGDDGVTWTEYKDPGAS-----------ESKIFPGNMDNNSHKKNIFETPFQARFVRIQPVAWHNRITLRV 422 HSP 2 Score: 95.5153 bits (236), Expect = 1.432e-19 Identity = 59/156 (37.82%), Postives = 92/156 (58.97%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKA---SQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ I ++QITASS K+W + + ARL + + +W A+ S SEWLQ+DLG++ ++G++TQG D Q+V ++ ++Y DG + KD S+ K+F GN D+ S K N F +ARF++ ++H +LRVE+LGC Sbjct: 273 PLGLKDNTIPNKQITASS-YYKTWGLSAFSWFPYYARLDNQGKFNAWTAQTNSASEWLQIDLGSQKRVTGIITQGARDFGHIQYVAAYRVAYGDDGVTWTEYKDPGASESKIFPGNMDNNSHKKNIFETPFQARFVRIQPVAWHNRITLRVELLGC 427
BLAST of Lactadherin vs. UniProt/SwissProt
Match: sp|O18806|FA8_CANLF (Coagulation factor VIII OS=Canis lupus familiaris OX=9615 GN=F8 PE=2 SV=1) HSP 1 Score: 149.443 bits (376), Expect = 6.565e-36 Identity = 108/337 (32.05%), Postives = 155/337 (45.99%), Query Frame = 3 Query: 114 YEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARL-YLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFH-YIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILS--------------NKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNG--TVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 Y K+C T PLGM G I+D QITAS + W ARL Y + +W K FS W++VDL +I G+MTQG + +V F+I YS DG +H Y + G+ VF GN DS +KHN FN I A++I+ H + +LR+E+LGC C LG+ T + +L+ W + N +W+Q+D + +T I T+G YV E+ +S S + NW + +QNG VF+GN DS++ N L P VAR+ R+HP +W I +R+ Sbjct: 2028 YSKKCQT--PLGMASGHIRDFQITASG-QYGQWAPKL----ARLHYSGSINAWSTK-DPFS-WIKVDLLAPMIIHGIMTQGARQKFSSLYVSQFIIMYSLDGNKWHSYRGNSTGTLMVFFGNVDSSGIKHNIFNPPIIAQYIRLHPTHYSIRSTLRMELLGCDFNSCSMPLGM--------ESKAISDAQITASSYLSSMLATWSPSQARLHLQGRTNAWRPQANNPKEWLQVDFRKTMKVTGITTQGVKSLLISMYVKEFLISSSQDGHNWTLF---------------LQNGKVKVFQGNRDSSTPVRNRLEPPLVARYVRLHPQSWAHHIALRL 2332 HSP 2 Score: 100.138 bits (248), Expect = 2.802e-20 Identity = 62/152 (40.79%), Postives = 84/152 (55.26%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDG--AQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM I D QITASS L S SQARL+L+ R +W + + EWLQVD ++G+ TQG + +V F+IS S DG N+ + G KVFQGNRDS + N + AR+++ H S+ H +LR+E+LGC Sbjct: 2188 PLGMESKAISDAQITASSY-LSSMLATWSPSQARLHLQGRTNAWRPQANNPKEWLQVDFRKTMKVTGITTQGVKSLLISMYVKEFLISSSQDGHNWTLFLQN-GKVKVFQGNRDSSTPVRNRLEPPLVARYVRLHPQSWAHHIALRLEVLGC 2337
BLAST of Lactadherin vs. TrEMBL
Match: A0A4S2LLD7 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006732 PE=4 SV=1) HSP 1 Score: 490.345 bits (1261), Expect = 4.345e-162 Identity = 267/679 (39.32%), Postives = 389/679 (57.29%), Query Frame = 3 Query: 36 FFFSNMRFLLLSCVICVASVIL-------------IDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPS---------------------------ERRSQFMKN------------------------------------ANKAVDGHTQWEM---------------DADDQQDSTNV----RIDRRINRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDL-------VENVDKISVFVDQYNSKGTNQFRKTSDL--LCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 F S + L L+ IC+ +L + EC PLGMI G I + QITASST SW C AR + N +WCAKFKS SEWLQ+DLG A+++G+MTQGRGDG++WV SFM+SYS DG + +I D Y +QK+F+GN DSF VKHNY ++ I+ARF+K HTY++H HPSLRVE++GCQPCK++LG+ PY + +S S+G++ R+C EYGH LSNK WC+++Q+ QW+QID+G P+ IT +I KGRGD K P YVT +++S+SN+++ WY+YK+ + P +F+GN + E+I+YL PF+AR+ R+HPINW+ +I MR+G+LGC+ KG C GF ++N+ S C+AN+AYKK AW+ +++ KRN+ S S ERR+ + N A+ AVDG T E+ +DD +++V ++R + R +CTVL+Y+ P WYV+L EQT V+GV+IY + + + + D EN++++SV+V+ GT ++ LCG VT+ N+A+ P++HI C+QP++G+FVY++A GV+ R +F A+LCEVMVY Sbjct: 1 MFGSQVLHLFLTGWICLQPGVLRLTAALEGEHDAHVPTPLPSECENDNPLGMISGTIANWQITASSTYPSSWAKGCSEHNARPFRPNGLAWCAKFKSSSEWLQIDLGVRALVTGIMTQGRGDGSEWVTSFMVSYSDDGNQWKFITDQYANQKIFEGNTDSFMVKHNYLDEPIKARFVKIHTYTWHNHPSLRVELVGCQPCKQLLGIPPYARFAASSSRGQRVQRSCMPEYGHYLSNKAWCSRQQDVQQWLQIDVGPPTQITGVILKGRGDYKRPQYVTRFKLSYSNDTRLWYFYKDATPLDPR-----------LFEGNNELVPERIHYLTSPFIARYVRVHPINWRNRIAMRVGLLGCRQKGPCTTGFFRINNESSCVANLAYKKSAWLNPDSSNPQKRNLPTSLSSINHSYQKDAASPEEASTVVRGPVHRQERRAPMLANHRIGETQTSSSKSMLHFWSANGIRSSPLSGETGDPMASLAVDGWTGEELFTRNSTLTLRSSEGVMSDDPSPTSSVDKHANVERGLERGAVRHSCTVLEYRWPFVELPSWYVDLREQTEVSGVVIYTAGHGRAASQGSHWSPADTDDKLKATSENLERLSVYVESEPRSGTGTALSSTSTSNLCGFVTRLNDAIFNPRLHIPCRQPLLGRFVYVEARGVRGRWSQEFSALLCEVMVY 668
BLAST of Lactadherin vs. TrEMBL
Match: A0A4S2LJG8 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006732 PE=4 SV=1) HSP 1 Score: 488.804 bits (1257), Expect = 3.541e-161 Identity = 269/692 (38.87%), Postives = 395/692 (57.08%), Query Frame = 3 Query: 36 FFFSNMRFLLLSCVICVASVIL-------------IDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMW---WIQN----------GTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPS---------------------------ERRSQFMKN------------------------------------ANKAVDGHTQWEM---------------DADDQQDSTNV----RIDRRINRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDL-------VENVDKISVFVDQYNSKGTNQFRKTSDL--LCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 F S + L L+ IC+ +L + EC PLGMI G I + QITASST SW C AR + N +WCAKFKS SEWLQ+DLG A+++G+MTQGRGDG++WV SFM+SYS DG + +I D Y +QK+F+GN DSF VKHNY ++ I+ARF+K HTY++H HPSLRVE++GCQPCK++LG+ PY + +S S+G++ R+C EYGH LSNK WC+++Q+ QW+QID+G P+ IT +I KGRGD K P YVT +++S+SN+++ WY+YK+ + P + +W W+ + +F+GN + E+I+YL PF+AR+ R+HPINW+ +I MR+G+LGC+ KG C GF ++N+ S C+AN+AYKK AW+ +++ KRN+ S S ERR+ + N A+ AVDG T E+ +DD +++V ++R + R +CTVL+Y+ P WYV+L EQT V+GV+IY + + + + D EN++++SV+V+ GT ++ LCG VT+ N+A+ P++HI C+QP++G+FVY++A GV+ R +F A+LCEVMVY Sbjct: 1 MFGSQVLHLFLTGWICLQPGVLRLTAALEGEHDAHVPTPLPSECENDNPLGMISGTIANWQITASSTYPSSWAKGCSEHNARPFRPNGLAWCAKFKSSSEWLQIDLGVRALVTGIMTQGRGDGSEWVTSFMVSYSDDGNQWKFITDQYANQKIFEGNTDSFMVKHNYLDEPIKARFVKIHTYTWHNHPSLRVELVGCQPCKQLLGIPPYARFAASSSRGQRVQRSCMPEYGHYLSNKAWCSRQQDVQQWLQIDVGPPTQITGVILKGRGDYKRPQYVTRFKLSYSNDTRLWYFYKDATPLDPRST-VWSYEWVHHVEEDGHTKELEKLFEGNNELVPERIHYLTSPFIARYVRVHPINWRNRIAMRVGLLGCRQKGPCTTGFFRINNESSCVANLAYKKSAWLNPDSSNPQKRNLPTSLSSINHSYQKDAASPEEASTVVRGPVHRQERRAPMLANHRIGETQTSSSKSMLHFWSANGIRSSPLSGETGDPMASLAVDGWTGEELFTRNSTLTLRSSEGVMSDDPSPTSSVDKHANVERGLERGAVRHSCTVLEYRWPFVELPSWYVDLREQTEVSGVVIYTAGHGRAASQGSHWSPADTDDKLKATSENLERLSVYVESEPRSGTGTALSSTSTSNLCGFVTRLNDAIFNPRLHIPCRQPLLGRFVYVEARGVRGRWSQEFSALLCEVMVY 691
BLAST of Lactadherin vs. TrEMBL
Match: G4VIR1 (Putative dock OS=Schistosoma mansoni OX=6183 GN=Smp_211020 PE=4 SV=1) HSP 1 Score: 458.373 bits (1178), Expect = 2.104e-150 Identity = 243/577 (42.11%), Postives = 370/577 (64.12%), Query Frame = 3 Query: 120 KECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMW---W----------IQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNI-GYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRINR---------KQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIY------NGNDILFSEKSENRAERDLVENVDKISVFVD-QYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 KEC PLGMI G I D QIT+SST SW C+ ARL+ N +WCAKFKS SEWLQ+DLG +A+ MTQGRGDG++WV SFM+SYS D ++ ++ D Y +QK+F+GN DS+SVKHNYF++ IRARF+K HTY++H HPSLRVE++GCQ CK+I+G+ PY + +S S+GK+ R+CT EYGH LSNK WCA++Q+ QW+QID+G P+LIT +I K RGD K+ YVT +++S+SN+++ WY+YK+ + P + +W W I++ +F+GN + +E+I+YL PF+AR+ RIHP+ W+ +I MR+G+LGCK KG C GF ++N+ S C+ + + ++ ++ M + G++ E +KN+ + + DA D + TN ++++ + ++ +CT+L+Y+ P WYV+L E V GV+IY +G +L S + EN++++S++V+ + T ++S LCG VT+ N+A+ P++HI C+QP++G++VY++A GV+ R +F A+LCEVMVY Sbjct: 45 KECENDDPLGMISGSIADWQITSSSTYPSSWVKGCEEKNARLFRTNGLAWCAKFKSSSEWLQIDLGVQAL----MTQGRGDGSEWVTSFMVSYSDDAMHWKFVTDQYANQKIFEGNSDSYSVKHNYFDEPIRARFVKIHTYTWHNHPSLRVELVGCQSCKQIIGIPPYARFAASSSRGKRSQRSCTPEYGHYLSNKAWCAQRQDALQWLQIDVGPPTLITGVILKSRGDVKNSQYVTRFKLSYSNDTRLWYFYKDAAPLDPRST-VWSFEWSQKMKESDDKIKSDKIFEGNNEQITERIHYLATPFIARYVRIHPVIWRSRIAMRVGLLGCKQKGSCSAGFFRINNESSCVNGMI--NEQFVGESSDGMALLAVDGWTGEE---ILLKNSTLSTRSSERLMNDAPDNKQLTNDSLNKKTIQNVVHTTFVTQKSAHSCTILEYRWPFVELPSWYVDLREHIEVKGVVIYTAGHGRDGRYLLSSLFGSEEKTKFNSENLERLSIYVESEPRHHDTKTLSRSSSSLCGFVTRINDAIFSPRLHIPCRQPLIGRYVYVEARGVRGRWSQEFAALLCEVMVY 611
BLAST of Lactadherin vs. TrEMBL
Match: R7T411 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_223186 PE=4 SV=1) HSP 1 Score: 441.81 bits (1135), Expect = 2.399e-144 Identity = 250/582 (42.96%), Postives = 351/582 (60.31%), Query Frame = 3 Query: 126 CNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYM-------W-WIQNGTV-------------------------FKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMK-NANKAVDGHTQWEMDADDQQDSTNVRIDRRINRKQHMRTCTVLQYKTSSNY---NPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 C+ GPLGMI GDI+D QITASST W C AR+Y N WC+K+KS SEWLQ+DLG A I+GVMTQGRGDG +WV SFM+SYS D ++ Y+ D YG+Q+VF+GN DS++VKH+Y +D I ARFIKFHT ++ HPS+RVEI+GCQ CK + + PYGK+ +S K KK +C E G++L+NKGWCAK N NQW+Q D+G P+L+T I+TKGRGD+ +VT +++++SN+++ WYYYK+ S P YM W W ++GT F GN D + E+ +YL PF ARF R HPI+W+ I MR G++GC G+C GF+++N +PC+ N+A+KK++WI + +KR+I R+Q+M +A +AVDG DD Q + +CT+L N+ PIW V+LG++ +NGV I + + RD + N+DK+ V+VD SKG + + +CG +++ N+AL KP +H+ C PM G++VYI+A GV +R F A+LCEV VY Sbjct: 38 CDLTGPLGMISGDIQDWQITASSTYPSEWDKGCHERYARVYQPNGLGWCSKYKSSSEWLQIDLGVAAKITGVMTQGRGDGVEWVTSFMVSYSMDAFHWQYVSDQYGNQRVFEGNTDSYAVKHSYLDDAIVARFIKFHTVHWNRHPSMRVEIIGCQVCKAPIALPPYGKLTASSVKPYKKGSSCMAEDGYLLTNKGWCAKHNNANQWLQFDVGPPTLVTGIVTKGRGDTGRKHWVTRFRIAYSNDTRVWYYYKDASHLDP-KFYMLAMSQRHWSWRRSGTAPNTTADTNATAMFMIPDRESPEGLEFGGNMDKSIERFHYLNSPFTARFIRFHPIDWENHISMRAGLIGCPFTGECTDGFMRINKYTPCVENLAFKKESWIN--NRRHYKRHI-------RNQWMHGHAGRAVDG--------DDDQS---------------LHSCTILD-----NFYVEKPIWMVDLGKKADINGVRIVTWQG---QGQDPRTSYRDYMYNLDKLVVYVD---SKGGKEQVDLEENMCGFISRLNDALFKPTLHVQCTSPMQGRYVYIEAWGVPNRWSRLFSAVLCEVQVY 575
BLAST of Lactadherin vs. TrEMBL
Match: K1QRH0 (Lactadherin OS=Crassostrea gigas OX=29159 GN=CGI_10015187 PE=4 SV=1) HSP 1 Score: 440.269 bits (1131), Expect = 3.594e-144 Identity = 244/563 (43.34%), Postives = 342/563 (60.75%), Query Frame = 3 Query: 126 CNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKE--NSESGPNNVYMW---------------WIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXX-XXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRINRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 C T GPLGMI G I+D QITASST W C AR+YL N+ WCAK+KS SEWL+VDLG A ++GVMTQGRGDG +WV SF +SYS D N Y+ D Y + +VF+GN D++SVKH Y + I AR+IKFHT +H HPS+RVEILGCQ CKE +G+ PYG+I +S + K+ +C E G+ILS KGWCAK+ N NQW+QID+G P+LIT ++TKGRGDSK +VT +++S+SN+++ WY YK+ + + P N ++W + +G +F GN D ++ +++Y+ PFVARF R HP+ W KI MR G+LG G CG+ F++VND +PC+ N+AYKK+AWI + K KR++ SP R +KAVDG +++ A CT+L P+W V+LG +T+V+G+IIY + E A +D + N+D++ ++VD N S +CG V+K N AL K+H+ C +P G++V ++A G + F A+LCEV+VY Sbjct: 18 CVTNGPLGMITGSIQDWQITASSTYPHEWDKKCAEKYARVYLPNKYGWCAKYKSSSEWLKVDLGVAARVTGVMTQGRGDGKEWVTSFKVSYSMDDYNELYVTDQYSNHRVFEGNTDAYSVKHTYLDRPIIARYIKFHTVHWHRHPSMRVEILGCQLCKESIGLPPYGRITTSSNGKNKRKDSCQPEDGNILSKKGWCAKRNNVNQWLQIDVGPPTLITGVMTKGRGDSKKKHWVTRFKISYSNDTQRWYQYKDAHSVDPRPQNPWLWNPLFNRTTAQLIPDIYTDDGLLFGGNNDKDTVRVHYINSPFVARFIRFHPLEWNGKISMRAGLLGCPHTAGNCGESFMRVNDDTPCVENLAYKKEAWINGKNPK--KRHV--SPKIDRGH----PDKAVDGKIDFDLHA-----------------------CTILDNLYGD--TPVWTVDLGAKTSVSGIIIYTWQESEGQMVKEGTAMKDYLNNLDRLVIYVD--NKSKAEDASSVSGNMCGYVSKLNGALLSHKIHVQCVRPQKGRYVLVEAWGSHNSWSRLFSAVLCEVLVY 545
BLAST of Lactadherin vs. Ensembl Cavefish
Match: edil3b (EGF-like repeat and discoidin I-like domain-containing protein 3 [Source:NCBI gene;Acc:103036235]) HSP 1 Score: 149.058 bits (375), Expect = 2.124e-38 Identity = 107/346 (30.92%), Postives = 171/346 (49.42%), Query Frame = 3 Query: 93 VILIDADYEK-ECNTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCT------EEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 +IL E+ C GPLGM G I +QQITASST L+ W A ARL NR+ +W + WLQV+L ++G++TQG R ++V S+ ++YS DG + +K + +F GN D+ S ++F+ I A++I+ + S H +LR E+LGC+ C E +G+ G I H+T + L +G W + +++QW+Q+D+ P+ +T IIT+G D H +V +++ FSN+ + W Y++ S+ +F+GN D+ + + N + P ARF RI P +W +I MR Sbjct: 118 LILTPPTKERCACECSGPLGMEGGIISNQQITASSTLHALFGLQKWH----AHLARL---NRRGLINAWSPAESDRAPWLQVNLERRLRVTGLITQGAKRIGSPEFVKSYKVAYSDDGKTWSTVKLKNTEEDMIFTGNTDNNSPAESHFSPPIEAQYIRIYPQSCRKHCTLRAELLGCELTGCSEPMGM-KTGHIQDDQISSSSVHQTLNINMFSWQPSKARLDKQGKVNAWTPAQNDQSQWLQVDLLLPTKVTGIITQGAKDFGHVQFVGSFKLGFSNDGEKWSIYQDESQ-----------HRDKIFQGNSDNETHRKNVIDPPIYARFLRIIPWSWYGRITMR 444 HSP 2 Score: 90.5077 bits (223), Expect = 9.033e-19 Identity = 57/167 (34.13%), Postives = 92/167 (55.09%), Query Frame = 3 Query: 126 CNTVG---PLGMIQGDIKDQQITASSTE------LKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 C G P+GM G I+D QI++SS + SW + S+ARL + + +W S+WLQVDL ++G++TQG D Q+V SF + +S DG + +D+ + K+FQGN D+ + + N + I ARF++ +S++G ++R E+LGC Sbjct: 288 CELTGCSEPMGMKTGHIQDDQISSSSVHQTLNINMFSW----QPSKARLDKQGKVNAWTPAQNDQSQWLQVDLLLPTKVTGIITQGAKDFGHVQFVGSFKLGFSNDGEKWSIYQDESQHRDKIFQGNSDNETHRKNVIDPPIYARFLRIIPWSWYGRITMRAELLGC 450
BLAST of Lactadherin vs. Ensembl Cavefish
Match: edil3b (EGF-like repeat and discoidin I-like domain-containing protein 3 [Source:NCBI gene;Acc:103036235]) HSP 1 Score: 144.821 bits (364), Expect = 4.539e-37 Identity = 108/353 (30.59%), Postives = 171/353 (48.44%), Query Frame = 3 Query: 102 IDADYEKEC-----------NTVGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCT------EEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 + ADY EC GPLGM G I +QQITASST L+ W A ARL NR+ +W + WLQV+L ++G++TQG R ++V S+ ++YS DG + +K + +F GN D+ S ++F+ I A++I+ + S H +LR E+LGC+ C E +G+ G I H+T + L +G W + +++QW+Q+D+ P+ +T IIT+G D H +V +++ FSN+ + W Y++ S+ +F+GN D+ + + N + P ARF RI P +W +I MR Sbjct: 103 LAADYSCECPREYAGKNCQYKCSGPLGMEGGIISNQQITASSTLHALFGLQKWH----AHLARL---NRRGLINAWSPAESDRAPWLQVNLERRLRVTGLITQGAKRIGSPEFVKSYKVAYSDDGKTWSTVKLKNTEEDMIFTGNTDNNSPAESHFSPPIEAQYIRIYPQSCRKHCTLRAELLGCELTGCSEPMGM-KTGHIQDDQISSSSVHQTLNINMFSWQPSKARLDKQGKVNAWTPAQNDQSQWLQVDLLLPTKVTGIITQGAKDFGHVQFVGSFKLGFSNDGEKWSIYQDESQ-----------HRDKIFQGNSDNETHRKNVIDPPIYARFLRIIPWSWYGRITMR 436 HSP 2 Score: 88.9669 bits (219), Expect = 2.777e-18 Identity = 55/159 (34.59%), Postives = 90/159 (56.60%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTE------LKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM G I+D QI++SS + SW + S+ARL + + +W S+WLQVDL ++G++TQG D Q+V SF + +S DG + +D+ + K+FQGN D+ + + N + I ARF++ +S++G ++R E+LGC Sbjct: 288 PMGMKTGHIQDDQISSSSVHQTLNINMFSW----QPSKARLDKQGKVNAWTPAQNDQSQWLQVDLLLPTKVTGIITQGAKDFGHVQFVGSFKLGFSNDGEKWSIYQDESQHRDKIFQGNSDNETHRKNVIDPPIYARFLRIIPWSWYGRITMRAELLGC 442
BLAST of Lactadherin vs. Ensembl Cavefish
Match: f5 (venom prothrombin activator omicarin-C non-catalytic subunit [Source:NCBI gene;Acc:103032429]) HSP 1 Score: 136.346 bits (342), Expect = 1.217e-32 Identity = 101/322 (31.37%), Postives = 148/322 (45.96%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIK-DDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHI-------LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 PLG+I G +KD QITAS + R S ARL+ + + + KS EW+QVD VIS V TQG + +V+++ ISYSTD + + K D ++K F+GNR++ VK N F I RFI+ H + P++R+E GC+ C LG+ + T Y L +G W AK + W+QI++ IT I+T+G +VT Y + +S + W Y ++ + +F GN D+N NY+ P +RF RI P W+ I MRI Sbjct: 1737 PLGLISGTVKDSQITASDS-----RSYWLPSLARLHNTGKYNAWSTTKS-GEWIQVDFQRPVVISKVATQGAKQFLTSHYVLNYTISYSTDRKRWIFYKADSKAARKTFEGNREAHEVKENIFFPPIIGRFIRLHPSHSYNFPTVRMEFYGCELDGCSVPLGM----QRNVIQDHQITASSVSTSWYSGPWHPWFARLDKQGSVNAWQAKSNDMQPWLQIELKAVKKITGIVTQGAKSLGTEMFVTAYVLEYSEDGNRWIKYTDDED-----------YEQKIFTGNTDNNGHVKNYIYPPIFSRFIRIIPKRWQNSITMRI 2037 HSP 2 Score: 78.5666 bits (192), Expect = 1.549e-14 Identity = 52/153 (33.99%), Postives = 79/153 (51.63%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG-RGDGAQ-WVVSFMISYSTDGTN-FHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM + I+D QITASS + ARL + +W AK WLQ++L I+G++TQG + G + +V ++++ YS DG Y D+ QK+F GN D+ NY I +RFI+ + ++R+E+LGC Sbjct: 1890 PLGMQRNVIQDHQITASSVSTSWYSGPWHPWFARLDKQGSVNAWQAKSNDMQPWLQIELKAVKKITGIVTQGAKSLGTEMFVTAYVLEYSEDGNRWIKYTDDEDYEQKIFTGNTDNNGHVKNYIYPPIFSRFIRIIPKRWQNSITMRIELLGC 2042
BLAST of Lactadherin vs. Ensembl Cavefish
Match: f8 (coagulation factor VIII, procoagulant component [Source:ZFIN;Acc:ZDB-GENE-090629-2]) HSP 1 Score: 135.961 bits (341), Expect = 1.365e-32 Identity = 101/330 (30.61%), Postives = 146/330 (44.24%), Query Frame = 3 Query: 114 YEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQ----WVVSFMISYSTDGTNFH-YIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSN-------KGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 Y C V PLGM G I D QIT S N +A ARL L +W + W+QVDL V+ G+ TQG + + V F ISYS D + Y + + F GN D + +K N+FN I R+I+ H +F P+LR+E+LGC C LG+ I +S H+ + L+ W K N ++W+Q+D+ +T I+T+G VTE+ VS S++ + W E +F+GN D+ +EK+N L P RF R+HP W I +R+ Sbjct: 1401 YNPRC--VQPLGMQSGWIDDDQITESDH-----YGNWEARLARLELSGSINAWIGNGQG--SWMQVDLLRPMVVHGIQTQGVKTSMRLSEMFAVIFTISYSLDQETWKTYRGNSSEAAYKFNGNMDGYRIKDNFFNPPIIGRYIRIHPLTFGTRPALRLELLGCDLNSCSLPLGM-ERRLIQNSRISASSFHQNWMLSWSPDLARLKQEGRANAWRPKSNNPHEWLQVDLEVVKRVTGILTQGAKSMLTHMMVTEFTVSVSDDGRTWSPVTEQG-----------THREQIFEGNSDAYAEKLNLLEPPLFTRFIRLHPKGWINDIALRL 1709 HSP 2 Score: 78.1814 bits (191), Expect = 1.791e-14 Identity = 50/153 (32.68%), Postives = 80/153 (52.29%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM + I++ +I+ASS ++W + ARL E R +W K + EWLQVDL ++G++TQG V F +S S DG + + + +++F+GN D+++ K N + RFI+ H + +LR+E LGC Sbjct: 1563 PLGMERRLIQNSRISASSFH-QNWMLSWSPDLARLKQEGRANAWRPKSNNPHEWLQVDLEVVKRVTGILTQGAKSMLTHMMVTEFTVSVSDDGRTWSPVTEQGTHREQIFEGNSDAYAEKLNLLEPPLFTRFIRLHPKGWINDIALRLEFLGC 1714
BLAST of Lactadherin vs. Ensembl Cavefish
Match: mfge8b (lactadherin-like [Source:NCBI gene;Acc:103047215]) HSP 1 Score: 123.635 bits (309), Expect = 1.094e-29 Identity = 91/350 (26.00%), Postives = 162/350 (46.29%), Query Frame = 3 Query: 102 IDADYEKECNT-----------VGPLGMIQGDIKDQQITASST-----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFH-YIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYG-----HILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 +D D+ +C++ + +GM G I + QI+ASS L+ W ARL + +W + + W+Q+++ + +G++TQG R A+++ SF ++ S DG + Y + + +F GN D+ S K N F+ I A++I+ +LR+E++GC+ C E LG E + L +G W A +K++W+Q+D+ P IT IIT+G D + +V+ +++++S++ ++W K++ + +F GN D+N K N PF ARF R+ P W E+I +R+ Sbjct: 132 LDGDFTCKCSSPFVGKHCQLRCISLMGMEGGGIAESQISASSVYYGILGLQRW----GPELARLNNKGLVNAWTSATHDKNPWIQINMQRKMRFTGIITQGASRMGSAEFIRSFKVASSLDGRTYTLYRAEGKKTDTIFAGNVDNDSTKTNLFDPPIIAQYIRILPVVCRKACTLRMELVGCELNGCSEPLGFKSRLISDRQLVSSSSFSTWGIEAFTWHPHYARLDKQGKTNAWTAATNSKSEWLQVDLLSPKRITGIITQGAKDFGNVQFVSAFKIAYSDDGQHWTVVKDDK-----------TRTDKIFPGNSDNNVHKKNVFEPPFYARFVRVLPWAWHERITLRM 466 HSP 2 Score: 89.7373 bits (221), Expect = 1.627e-18 Identity = 59/159 (37.11%), Postives = 89/159 (55.97%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG I D+Q+ +SS+ E +W + ARL + + +W A S SEWLQVDL + I+G++TQG D Q+V +F I+YS DG ++ +KDD + K+F GN D+ K N F ARF++ +++H +LR+E+LGC Sbjct: 317 PLGFKSRLISDRQLVSSSSFSTWGIEAFTWHPH----YARLDKQGKTNAWTAATNSKSEWLQVDLLSPKRITGIITQGAKDFGNVQFVSAFKIAYSDDGQHWTVVKDDKTRTDKIFPGNSDNNVHKKNVFEPPFYARFVRVLPWAWHERITLRMELLGC 471
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007561.1 (pep scaffold:Pmarinus_7.0:GL479407:10781:33713:1 gene:ENSPMAG00000006808.1 transcript:ENSPMAT00000007561.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 115.546 bits (288), Expect = 6.682e-27 Identity = 91/333 (27.33%), Postives = 152/333 (45.65%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASSTEL-KSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQG----RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ----PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILS-NKGWCAKKQNK---NQWIQIDIGQPSLITAIITKG-RGD------SKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINW-KEKIGMRI 1058 +CN PLGM G ++ +I ASST + W + QARL+ W EW+QVDLG+ ++SGV TQG +V SF + S+ G ++ ++ + K F GN D+ SV N + + RF++ ++ G +LR E+ GC PC E LGV ++ S + +L+ +GW ++W+Q+D+G + +I +G RGD + P +V +++V FS + W+ ++ S P +F G+ + + ++ EP AR R++P W IG+R+ Sbjct: 201 QCNQ--PLGMESGKVEVDRIVASSTHSSRMW----QPWQARLH-NPINGWTPSRDDPREWIQVDLGSLKLLSGVATQGAVSHESQIGYFVSSFRLEVSSLGADWTVLRGSR-AVKAFAGNVDATSVVENRLAEPVLTRFVRIRPQTWEGGIALRFELYGCSLADFPCLETLGVGQGHVPDNALSASSQWSPPWGAHAARLLAPQRGWAPHMAGLFSFDEWLQVDLGSLFTVRGVILQGVRGDLGTQDKPEGPLFVKKFRVGFSEDGDTWHMVTDDESSQPK-----------IFNGSSNVDLPEMRKF-EPVEARLVRVYPERWSPHGIGLRL 513 HSP 2 Score: 83.1889 bits (204), Expect = 8.832e-17 Identity = 60/164 (36.59%), Postives = 86/164 (52.44%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWC---AKFKSFSEWLQVDLGTEAVISGVMTQG-RGD--------GAQWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHT--YSFHGHPSLRVEILGCQ 590 LG+ QG + D ++ASS W A ARL L ++ W A SF EWLQVDLG+ + GV+ QG RGD G +V F + +S DG +H + DD SQ K+F G+ + + F + + AR ++ + +S HG LR+E+LGCQ Sbjct: 363 LGVGQGHVPDNALSASS----QWSPPWGAHAARL-LAPQRGWAPHMAGLFSFDEWLQVDLGSLFTVRGVILQGVRGDLGTQDKPEGPLFVKKFRVGFSEDGDTWHMVTDDESSQPKIFNGSSNVDLPEMRKF-EPVEARLVRVYPERWSPHGI-GLRLELLGCQ 519
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Match: EDIL3 (EGF like repeats and discoidin domains 3 [Source:HGNC Symbol;Acc:HGNC:3173]) HSP 1 Score: 106.686 bits (265), Expect = 9.281e-25 Identity = 96/352 (27.27%), Postives = 145/352 (41.19%), Query Frame = 3 Query: 102 IDADYEKECN-----------TVGPLGMIQGDIKDQQITASS-----TELKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDY-GSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCT----EEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 +DADY EC PLG+ GDI+D QITASS L+ W S ARL NR +W + W+QV+L ++GV+TQG R A++V +F +++S DG N+ +D G KVF GN+D+ S + N + I A ++ + +LR+E+LGC+ C E LG+ + S E + L +G W A K + NQW+Q+ + + + R Q+ F GN D+NS K N P +AR+ R+ P +W +I +R+ Sbjct: 147 LDADYSCECTGEFMGKDCHLRCWSPLGLEGGDIRDDQITASSLLVAVMGLQRW----LPSLARL---NRAGIVNAWTPAQRDSQPWIQVNLERRLRVTGVVTQGASRFGSAEYVRTFKLAHSGDGRNWTVYRDAATGRDKVFLGNQDNGSPRSNTLSPPIVASLVRLMPLTCRRRCTLRMELLGCETNGCSEPLGLKSGLVGDTQISASSVFQTLLPCWTWEPHLARLDRQGRINAWSAAKGDPNQWLQVCV--------LEAQKRTCCFVCVCFFFLQI---------------------------------FAGNYDNNSHKKNMFNPPIIARYVRVLPYSWYRRITLRV 450
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004027.1 (pep scaffold:Pmarinus_7.0:GL481210:3001:5030:1 gene:ENSPMAG00000003685.1 transcript:ENSPMAT00000004027.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 91.2781 bits (225), Expect = 8.323e-22 Identity = 60/157 (38.22%), Postives = 88/157 (56.05%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST----ELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGA--QWVVSFMISYSTDGTNFHYIKDDYGSQ-KVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLG+ G + D QI+ASS L W + ARL + R +W A ++WLQ+DLG I+G++TQG D Q+V S+ ++ S DG + KDD + K+F GN D+ S K N FN I AR+++ YS++ +LRVE++GC Sbjct: 5 PLGLKSGLVGDTQISASSVFQTLGLPCW--TWEPHLARLDRQGRINAWSAAKGDPNQWLQIDLGEARKITGIVTQGARDLGHMQFVRSYRVASSEDGAAWTVYKDDETRRDKIFAGNYDNNSHKKNMFNPPIIARYVRVLPYSWYRRITLRVELIGC 159 HSP 2 Score: 84.3445 bits (207), Expect = 2.654e-19 Identity = 40/117 (34.19%), Postives = 62/117 (52.99%), Query Frame = 3 Query: 708 GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 W A K + NQW+QID+G+ IT I+T+G D H +V Y+V+ S + W YK++ + +F GN D+NS K N P +AR+ R+ P +W +I +R+ Sbjct: 49 AWSAAKGDPNQWLQIDLGEARKITGIVTQGARDLGHMQFVRSYRVASSEDGAAWTVYKDDE-----------TRRDKIFAGNYDNNSHKKNMFNPPIIARYVRVLPYSWYRRITLRV 154
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001939.1 (pep scaffold:Pmarinus_7.0:GL476444:333387:405756:1 gene:ENSPMAG00000001736.1 transcript:ENSPMAT00000001939.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.9821 bits (245), Expect = 9.503e-22 Identity = 81/319 (25.39%), Postives = 145/319 (45.45%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASST-ELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGR----GDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ----PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNK-GWCAKKQNK-----NQWIQIDIGQPSLITAIITKGRGDSKHP---TYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHP 1025 +CN PLGM +I+D+QITASS K W QARL +W S EW+Q DLG ++SG+ TQG + +V S+ + S++G ++ +K+ + + + N D+ S+ N F++ + RF++ S+ +LR E+ GC PC +LG+ ++ +LS+ GW + +W+Q+++G + II +G P +V +++++ S + + W E+ P +F+GN + ++ ++ EP VA + RI+P Sbjct: 192 KCNQ--PLGMESLEIRDEQITASSMYPNKEWMPK----QARLN-NPVHAWTPAADSNKEWIQADLGYLKILSGIATQGAISKDSKKSYYVTSYKMEVSSNGDDWMMLKEGI-TIIILRNNSDASSLVENKFSEPVLTRFVRVRPRSWENGIALRFELYGCHISDYPCSGMLGMLSGRIQDGQLQSSSQRGLNWAPSSARLLSSAYGWAPMPPHGASHPVGEWLQVELGGRHTVRGIILQGAKSGTVPDNRLHVRKFRLATSLDGETWEMISEDDSDLPK-----------LFEGNSNYDTPELRKF-EPVVASWVRIYP 490 HSP 2 Score: 62.003 bits (149), Expect = 2.722e-10 Identity = 34/118 (28.81%), Postives = 54/118 (45.76%), Query Frame = 3 Query: 711 WCAKKQNKNQWIQIDIGQPSLITAIITKG--RGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 W + +WIQ D+G +++ I T+G DSK YVT Y++ S+N +W KE + + N D++S N EP + RF R+ P +W+ I +R Sbjct: 234 WTPAADSNKEWIQADLGYLKILSGIATQGAISKDSKKSYYVTSYKMEVSSNGDDWMMLKEGITI-------------IILRNNSDASSLVENKFSEPVLTRFVRVRPRSWENGIALRF 338
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003059.1 (pep scaffold:Pmarinus_7.0:GL476485:229541:264028:1 gene:ENSPMAG00000002790.1 transcript:ENSPMAT00000003059.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 97.4413 bits (241), Expect = 1.589e-21 Identity = 86/345 (24.93%), Postives = 149/345 (43.19%), Query Frame = 3 Query: 111 DYEKECNTVGPLGMIQGDIKDQQITASST-ELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGR----GDGAQ-WVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ----PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG---WCAKKQNKNQWIQIDIGQPSLITAIITKG---------------RGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKE-KIGMRI 1058 D E + PLGM G+I D+QI+AS + WR A Q RL+ A +S EWLQVDL ++ V TQG G +V +F + YST G+++ +D KV QGNRD V + F + + AR+++ +HG LR+E+ GC PC E+LG+ S + + + C NK W+ +D+G ++ ++ +G +++ +V +++ S + ++W ++ + + +F GN +++ ++ + +ARF R+ P W IG+R+ Sbjct: 235 DRHGEGACMRPLGMESGEILDEQISASPGFYAEQWR----AEQTRLHRAGAACIHAPTESAREWLQVDLRFVRLLGAVATQGALASNSTGVPCFVTAFRLEYSTSGSDWTVYRD-VEKNKVIQGNRDDGGVALHRFAEAVVARYVRVKPVRWHGGLGLRLELYGCHISDAPCSEMLGLVSGEIGDRQLSASSSRDARWAPPLAPPAAGRSLLFLCQFYLNKF-WLNVDLGTTRQVSGLLLQGAKIGPTKRRRPPLRLPLETESKVFVRSFRLQLSLDGESWAGVQDPAGA------------DKIFPGNSNADKPELRQINAT-LARFLRLFPEKWSTNGIGVRL 560 HSP 2 Score: 62.3882 bits (150), Expect = 2.210e-10 Identity = 49/168 (29.17%), Postives = 80/168 (47.62%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQ-ARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQ-----------------WVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKF--HTYSFHGHPSLRVEILGC 587 LG++ G+I D+Q++ASS+ W R L + + KF WL VDLGT +SG++ QG G +V SF + S DG ++ ++D G+ K+F GN ++ + N + ARF++ +S +G +R+E+LGC Sbjct: 405 LGLVSGEIGDRQLSASSSRDARWAPPLAPPAAGRSLLFLCQFYLNKF-----WLNVDLGTTRQVSGLLLQGAKIGPTKRRRPPLRLPLETESKVFVRSFRLQLSLDGESWAGVQDPAGADKIFPGNSNADKPELRQINATL-ARFLRLFPEKWSTNGI-GVRLEVLGC 565
BLAST of Lactadherin vs. Ensembl Nematostella
Match: EDO29609 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T356]) HSP 1 Score: 160.999 bits (406), Expect = 1.123e-42 Identity = 109/322 (33.85%), Postives = 166/322 (51.55%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-------SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ-----PCKEILGVFPYXXXXXXXXXXXXXH-----RTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 LG+ G IKD Q+TASS W +N A+ ARL NR+ +W AK + +WLQVDLG + + V TQGR D QWV ++ ++YS DG F Y KV GN+D +V + I AR+++F+ ++HGH S+RVE+ GC+ P + +++ S+ H R T GH + W A+ N QW+QID+G+ + +TAI+T+GR D +VT+Y++ +S N +++ Y +G VF+GN D NS+ + L+ +AR+ R+ P W I MR+ Sbjct: 214 LGVQSGFIKDAQMTASSI----WDNNHGAANARL---NRQKIGARTGAWSAKHNNRLQWLQVDLGKLSKVVKVATQGRQDLNQWVTTYKLAYSRDGVLFKYFP------KVLSGNKDRNTVV-THSVGPIYARYVRFYPQTWHGHISMRVELYGCRRGFVDPLVKCAAPLKKKTKVTASSQWDANHSPERSRLDTIRQGHKIG--AWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQ--WVTQYKLEYSQNRVHFHSY----------------LSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHAHISMRV 501 HSP 2 Score: 129.798 bits (325), Expect = 5.791e-32 Identity = 94/316 (29.75%), Postives = 149/316 (47.15%), Query Frame = 3 Query: 168 KDQQITASSTELKSWRDNCKASQARL--YLENRK--SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ---------PCKEILGV---FPYXXXXXXXXXXXXXHRTCTEEYGH--ILSNKG-WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K ++TASS W N ++RL + K +W A+ + ++WLQ+DLG ++ ++TQGR D QWV + + YS + +FH Y S KVFQGN D S + I AR+I+ ++H H S+RV + GC+ CK LGV F +++ S H I + G W AK N+ QW+Q+D+G+ S + + T+GR D +VT Y++++S + + Y+ + V GN+D N+ + + P AR+ R +P W I MR+ Sbjct: 63 KKTKVTASS----QWDANHSPERSRLDTIRQGHKIGAWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQWVTQYKLEYSQNRVHFH----SYLSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHAHISMRVGLYGCRKGFKPPPLWSCKHTLGVQSGFIKDAQMTASSIWDNNHGAANARLNRQKIGARTGAWSAKHNNRLQWLQVDLGKLSKVVKVATQGRQDLNQ--WVTTYKLAYSRDGVLFKYFPK------------------VLSGNKDRNTV-VTHSVGPIYARYVRFYPQTWHGHISMRV 349 HSP 3 Score: 89.3521 bits (220), Expect = 1.011e-18 Identity = 54/157 (34.39%), Postives = 83/157 (52.87%), Query Frame = 3 Query: 135 VGPLGMIQGDIKDQ-QITASSTELKSWRDNCKASQARL--YLENRK--SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ 590 V PL +K + ++TASS W N ++RL + K +W A+ + ++WLQ+DLG ++ ++TQGR D QWV + + YS + +FH Y S KVFQGN D S + I AR+I+ ++H H S+RV + GC+ Sbjct: 359 VDPLVKCAAPLKKKTKVTASS----QWDANHSPERSRLDTIRQGHKIGAWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQWVTQYKLEYSQNRVHFH----SYLSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHAHISMRVGLYGCR 507
BLAST of Lactadherin vs. Ensembl Nematostella
Match: EDO46788 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP38]) HSP 1 Score: 160.614 bits (405), Expect = 2.188e-41 Identity = 110/322 (34.16%), Postives = 165/322 (51.24%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-------SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ-----PCKEILGVFPYXXXXXXXXXXXXXH-----RTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 LG+ G IKD Q+TASS W +N A+ ARL NR+ +W AK +WLQVDLG + + V TQGR D QWV ++ ++YS DG F Y KV GN+D +V + I AR+++FH ++HGH S+RVE+ GC+ P + +++ S+ H R T GH + W A+ N QW+QID+G+ + +TAI+T+GR D +VT+Y++ +S N +++ Y +G VF+GN D NS+ + L+ +AR+ R+ P W I MR+ Sbjct: 293 LGVQSGFIKDAQMTASSI----WDNNHGAANARL---NRQKIGAITGAWSAKQNDRLQWLQVDLGKLSKVVKVATQGRQDLNQWVTTYKLAYSRDGVLFKYFP------KVLSGNKDRNTVVTHSVGT-IYARYVRFHPQTWHGHISMRVELYGCRRGFVAPPVKCAAPLEKKNKVTASSQWDANHSPERSRLDTIRQGHKIG--AWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQ--WVTQYKLEYSQNRVHFHSY----------------LSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHTHISMRV 580 HSP 2 Score: 129.413 bits (324), Expect = 2.957e-31 Identity = 97/330 (29.39%), Postives = 156/330 (47.27%), Query Frame = 3 Query: 135 VGPLGMIQGDIKDQ-QITASSTELKSWRDNCKASQARL--YLENRK--SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ---------PCKEILGV---FPYXXXXXXXXXXXXXH-----RTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 V PL +K + ++TASS W N ++RL + K +W A+ + ++WLQ+DLG ++ ++TQGR D QWV + + YS + +FH Y S KVFQGN D S + I AR+I+ ++H H S+RV + GC+ CK LGV F +++ S H R ++ G I W AK+ ++ QW+Q+D+G+ S + + T+GR D +VT Y++++S + + Y+ + V GN+D N+ + + AR+ R HP W I MR+ Sbjct: 130 VDPLVKCAAPLKKKTKVTASS----QWDANHSPERSRLDTIRQGHKIGAWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQWVTQYKLEYSQNRVHFH----SYLSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHAHISMRVGLYGCRKGFKPPPLWSCKHTLGVQSGFIKDAQMTASSIWDNNHGAANARLNRQKIGAITG--AWSAKQNDRLQWLQVDLGKLSKVVKVATQGRQDLNQ--WVTTYKLAYSRDGVLFKYFPK------------------VLSGNKDRNTV-VTHSVGTIYARYVRFHPQTWHGHISMRV 428 HSP 3 Score: 125.946 bits (315), Expect = 4.466e-30 Identity = 93/316 (29.43%), Postives = 148/316 (46.84%), Query Frame = 3 Query: 168 KDQQITASSTELKSWRDNCKASQARL--YLENRK--SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ---------PCKEILGV---FPYXXXXXXXXXXXXXHRTCTEEYGH--ILSNKG-WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K ++TASS W N ++RL + K +W A+ + ++WLQ+DLG ++ ++TQGR D QWV + + YS + +FH Y S KVFQGN D S + I AR+I+ ++H H S+RV + GC+ CK LGV F +++ S H I + G W AK ++ QW+Q+D+G+ S + + T+GR D +VT Y++++S + + Y+ + V GN+D N+ + + AR+ R HP W I MR+ Sbjct: 450 KKNKVTASS----QWDANHSPERSRLDTIRQGHKIGAWSARHNNIAQWLQIDLGKATKVTAIVTQGRSDLDQWVTQYKLEYSQNRVHFH----SYLSGKVFQGNHDRNSKLSHILKPAIIARYIRVRPQAWHTHISMRVGLYGCRKGFKPPPLWSCKHTLGVQSGFIKDAQMTASSIWDNNHGAANARLNRQKIGARTGAWSAKHNDRLQWLQVDLGKLSKVVKVATQGRQDLNQ--WVTTYKLAYSRDGVLFKYFPK------------------VLSGNKDRNTV-VTHSVGTIYARYVRFHPQTWHGHISMRV 736 HSP 4 Score: 103.219 bits (256), Expect = 7.406e-23 Identity = 64/156 (41.03%), Postives = 88/156 (56.41%), Query Frame = 3 Query: 144 LGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK-------SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ 590 LG+ G IKD Q+TASS W +N A+ ARL NR+ +W AK +WLQVDLG + + V TQGR D QWV ++ ++YS DG F Y KV GN+D +V + I AR+++FH ++HGH S+RVE+ GC+ Sbjct: 601 LGVQSGFIKDAQMTASSI----WDNNHGAANARL---NRQKIGARTGAWSAKHNDRLQWLQVDLGKLSKVVKVATQGRQDLNQWVTTYKLAYSRDGVLFKYFP------KVLSGNKDRNTVVTHSVGT-IYARYVRFHPQTWHGHISMRVELYGCR 742
BLAST of Lactadherin vs. Ensembl Nematostella
Match: EDO48080 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK12]) HSP 1 Score: 153.68 bits (387), Expect = 5.394e-40 Identity = 101/323 (31.27%), Postives = 155/323 (47.99%), Query Frame = 3 Query: 117 EKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNF-HYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILGVFPYXXXXXXXXXXXXXHRTCT----EEYGHILSNKG--WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 K CN P+GM + I + +ITASS + + N QA W + + +WLQVD G + I + +QG D WV F +S S D +F Y+ ++ + K F GNRD SV N FN IRAR+I+ H Y + ++RVE GC C +G+ ++ C+ +G +G WCA+ N+ QWIQ+D G + +T ++T+GR +S +V Y V++S+N N+ YKEN + +F+GN D N + P R+ R+HP++W +I MR+ Sbjct: 206 RKMCNL--PMGMEKRGISNARITASSQYNRYFAANRGRLQAARQGRYLGGWRPRVNNRYQWLQVDFGKPSKIVRIASQGHRDYDYWVTRFSVSSSVDLVHFVQYM--EFSAIKYFTGNRDRNSVVPNVFNPSIRARYIRVHPYGWRSQIAMRVEFYGCHTNRCDMPIGLESGTIADPQFRASSFQNFYCSAFNARLHGTRAGRRGGAWCARALNRKQWIQVDFGTSARVTRVVTQGRQNSNQ--WVKSYYVTYSSNGINFKIYKENGKR-------------KIFEGNYDRYIPVTNTFKTPLNGRYFRVHPVSWHSRIAMRL 509 HSP 2 Score: 134.035 bits (336), Expect = 2.796e-33 Identity = 90/327 (27.52%), Postives = 151/327 (46.18%), Query Frame = 3 Query: 117 EKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ-------PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNK------GWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 E C+T PLG+ I+ + +S + Q R + R W + + +WLQ++LG + ++ + QGR D QW +F +SYS DG+ F + K +++FQGN D + V + A++++ H +++GH +LR EI GC+ C +G+ G + + + +R G + + + GW + N+ QW+Q+D G+PS I I ++G D + +VT + VS S + ++ Y E S F GN D NS N AR+ R+HP W+ +I MR+ Sbjct: 46 EDPCDT--PLGVQDHRIRKSMFSTTSMANHYYGPWSSKLQDRNHGHYRGGWVPRINNNKQWLQINLGARSRVNRIAIQGRYDANQWTETFKLSYSKDGSKFAFYKVG-KYERIFQGNNDRYRVNVLRLIPPVVAQYVRIHPQTWYGHVALRTEIYGCRIGKRSRKMCNLPMGMEKRGISNARITASSQYNRYFAANRGRLQAARQGRYLGGWRPRVNNRYQWLQVDFGKPSKIVRIASQGHRDYDY--WVTRFSVSSSVDLVHFVQYMEFSAI-------------KYFTGNRDRNSVVPNVFNPSIRARYIRVHPYGWRSQIAMRV 354 HSP 3 Score: 105.145 bits (261), Expect = 8.522e-24 Identity = 56/153 (36.60%), Postives = 88/153 (57.52%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARLY--LENRK--SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+G+ G I D Q ASS + C A ARL+ R+ +WCA+ + +W+QVD GT A ++ V+TQGR + QWV S+ ++YS++G NF K++ G +K+F+GN D + N F + R+ + H S+H ++R+E GC Sbjct: 367 PIGLESGTIADPQFRASSFQ----NFYCSAFNARLHGTRAGRRGGAWCARALNRKQWIQVDFGTSARVTRVVTQGRQNSNQWVKSYYVTYSSNGINFKIYKEN-GKRKIFEGNYDRYIPVTNTFKTPLNGRYFRVHPVSWHSRIAMRLEFFGC 514 HSP 4 Score: 85.8853 bits (211), Expect = 1.458e-17 Identity = 58/208 (27.88%), Postives = 93/208 (44.71%), Query Frame = 3 Query: 456 FQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHR------TCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 F+GNRD SV + +IR R I+ + Y++ H S+RVE GC PC LGV + S S + + ++ H GW + N QW+QI++G S + I +GR D+ + +++S+S + + +YK +F+GN D + L P VA++ RIHP W + +R Sbjct: 1 FKGNRDQNSVVMHRLFPRIRCRVIRLYPYTWRSHMSMRVEFYGCAEDPCDTPLGVQDHRIRKSMFSTTSMANHYYGPWSSKLQDRNHGHYRGGWVPRINNNKQWLQINLGARSRVNRIAIQGRYDANQ--WTETFKLSYSKDGSKFAFYKVGKYE-------------RIFQGNNDRYRVNVLRLIPPVVAQYVRIHPQTWYGHVALR 193
BLAST of Lactadherin vs. Ensembl Nematostella
Match: EDO48077 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK09]) HSP 1 Score: 144.05 bits (362), Expect = 3.164e-38 Identity = 103/320 (32.19%), Postives = 151/320 (47.19%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS---TELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP--CKEILG------VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDI----GQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 PLGM I+ Q++A++ L W L +R SW AK ++WLQ+ + ++GV TQGR D QWV + + +STDGT F + S K+FQ NRD SV +N N I ARF++ + Y + + S+R E GC C LG + S S+ +E H W AK +N+NQWIQ+D+ G+PS + + T+G D + +VT+Y +++S + + YK NS N F GN D ++ + L P AR+ RIHP W IG+R Sbjct: 20 PLGMEDKRIRPGQLSANNFYNHHLSPWNSR---------LNSRYSWSAKASDHNQWLQIQF-DQTKVTGVATQGRQDAHQWVTRYNLLHSTDGTTFTTYRYP-SSDKLFQANRDRSSVVYNALNPPIYARFLRINPYGWRSYISMRAEFYGCATDQCNLPLGFQDGRITRSHMTASSLYSQYYGPWNARIQETNHGQVRGAWIAKIRNQNQWIQVDLEFDFGRPSKVVRVSTQGMQDRNY--WVTQYYMTYSLDGLRFLEYKHNS-------------NRKYFTGNRDRSTAVSHVLYPPIRARYVRIHPWGWHAYIGLR 313 HSP 2 Score: 85.5001 bits (210), Expect = 4.092e-18 Identity = 52/160 (32.50%), Postives = 80/160 (50.00%), Query Frame = 3 Query: 123 ECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDL----GTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ 590 +CN PLG G I +TASS + + Q + + R +W AK ++ ++W+QVDL G + + V TQG D WV + ++YS DG F K + ++K F GNRD + + IRAR+++ H + +H + LR E GC Sbjct: 164 QCNL--PLGFQDGRITRSHMTASSLYSQYYGPWNARIQETNHGQVRGAWIAKIRNQNQWIQVDLEFDFGRPSKVVRVSTQGMQDRNYWVTQYYMTYSLDGLRFLEYKHN-SNRKYFTGNRDRSTAVSHVLYPPIRARYVRIHPWGWHAYIGLRAEFFGCH 320
BLAST of Lactadherin vs. Ensembl Nematostella
Match: EDO41038 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S5M9]) HSP 1 Score: 147.902 bits (372), Expect = 5.490e-38 Identity = 97/321 (30.22%), Postives = 169/321 (52.65%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASSTELKSWRDNCKASQARL--YLEN--RKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP----CKEILGVFPYXXXXX---XXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 PLGM I D +ITASST L S N +ARL L++ + +W AK +WLQ+D+G ++ ++TQGR D QWV S+ I +S FH DY + F+GN+D+ + + N I AR+++ ++HGH S+R+E+ GC C + +G S + S+ +R H+ +N+G W + +KN W++ID+G+ + +T I T+G+ D+ + +VT Y + +S + ++ + + +N +F+GN+D ++ + + L P +AR+ R+ P+ W+ +I MR+ Sbjct: 160 PLGMKSKAITDSRITASST-LNS---NHSPQRARLDTVLQDSLKGAWSAKTNDMGQWLQIDMGRATKVTRIVTQGRSDANQWVKSYKIQFSQQDL-FH----DYREGRTFEGNKDTNTKYGHVLNPPIIARYVRVLPVTWHGHISMRMELFGCTEGEFKCLKAIGAQSGTLKDSQFFASSELSSSYRASNARL-HLHTNRGRVGAWSPSRSDKNPWLEIDVGRIAKVTGISTQGQQDANY--WVTSYALQYSLDGSSFTTFSVS-------------RNPKIFEGNKDRSTVRSHALAMPILARYVRVRPMTWRGRIAMRV 455 HSP 2 Score: 146.747 bits (369), Expect = 1.418e-37 Identity = 97/321 (30.22%), Postives = 156/321 (48.60%), Query Frame = 3 Query: 150 MIQGDIKDQQITASSTELKSWRDNCKASQARLYL----ENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--------PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHI-----LSNKG-WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 M G IKD Q+ ASS SW N A ++RL++ R +W A++ ++LQVD ++ + QGR D QWV + +SYS DG + + G+ K F GNRD +V + + I RF++ H ++ H SLR+E GC+ C LG+ S + + + + + S KG W AK + QW+QID+G+ + +T I+T+GR D+ +V Y++ FS ++ Y+E G F+GN+D+N++ + L P +AR+ R+ P+ W I MR+ Sbjct: 1 MASGAIKDAQLNASS----SWDRNHGAGRSRLHIVRASGKRGAWSARYNDRGQYLQVDFSKPIKLTKIDIQGREDANQWVTEYWVSYSLDGGIYRPLYTPKGNVKYFIGNRDRNTVVSSVLEEPIYPRFVRIHPSKWYQHISLRLEFHGCRNDFEIPKVLCASPLGMKSKAITDSRITASSTLNSNHSPQRARLDTVLQDSLKGAWSAKTNDMGQWLQIDMGRATKVTRIVTQGRSDANQ--WVKSYKIQFSQQDL-FHDYRE----------------GRTFEGNKDTNTKYGHVLNPPIIARYVRVLPVTWHGHISMRM 298 HSP 3 Score: 107.457 bits (267), Expect = 1.469e-24 Identity = 74/265 (27.92%), Postives = 119/265 (44.91%), Query Frame = 3 Query: 48 NMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQP---------CKEILGVFPYXXXXXXXXXXXXXHRTCTEE------YGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAI 785 +MR L C E E + +G G +KD Q ASS S+R AS ARL+L + +W + WL++D+G A ++G+ TQG+ D WV S+ + YS DG++F + K+F+GN+D +V+ + I AR+++ ++ G ++RVEI GC C LG+ + + T Y H GW ++K + QW+Q+D+G+ S +T I Sbjct: 295 SMRMELFGCT-------------EGEFKCLKAIGAQSGTLKDSQFFASSELSSSYR----ASNARLHLHTNRGRVGAWSPSRSDKNPWLEIDVGRIAKVTGISTQGQQDANYWVTSYALQYSLDGSSFTTFSVSR-NPKIFEGNKDRSTVRSHALAMPILARYVRVRPMTWRGRIAMRVEIFGCTSGFPLPPVPECMAPLGLQRHIIKDNQMEASSVWSNTHGAANARLYFYPHDGRTGGWSSRKNDGAQWLQVDLGKQSKVTMI 541
BLAST of Lactadherin vs. Ensembl Medaka
Match: edil3a (EGF like repeats and discoidin domains 3 [Source:NCBI gene;Acc:101165646]) HSP 1 Score: 133.65 bits (335), Expect = 3.207e-33 Identity = 102/332 (30.72%), Postives = 162/332 (48.80%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYI----KDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + KDD +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W A +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ + W Y++ + VF+GN D+++ + N + P AR RI P +W +I +R Sbjct: 116 GPLGMEGGIISNQQITASSTHRALFGLQKW----YPYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYRVKGKDD---DMIFRGNVDNNAPSANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELTGCSEPLGMKSGHIQDYQVTASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQG-----------KDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLR 426 HSP 2 Score: 97.0561 bits (240), Expect = 4.675e-21 Identity = 60/159 (37.74%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D Q+TASS ++ +W + +ARL + + +W A S+WLQVDL ++G++TQG D Q+V S+ I+YS DG ++ +D+ G KVFQGN D+ + + N + I AR ++ +S++G +LR EILGC Sbjct: 278 PLGMKSGHIQDYQVTASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQGKDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLRAEILGC 432
BLAST of Lactadherin vs. Ensembl Medaka
Match: edil3a (EGF like repeats and discoidin domains 3 [Source:NCBI gene;Acc:101165646]) HSP 1 Score: 133.265 bits (334), Expect = 3.414e-33 Identity = 102/332 (30.72%), Postives = 162/332 (48.80%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYI----KDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + KDD +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W A +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ + W Y++ + VF+GN D+++ + N + P AR RI P +W +I +R Sbjct: 106 GPLGMEGGIISNQQITASSTHRALFGLQKW----YPYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYRVKGKDD---DMIFRGNVDNNAPSANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELTGCSEPLGMKSGHIQDYQVTASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQG-----------KDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLR 416 HSP 2 Score: 97.0561 bits (240), Expect = 4.944e-21 Identity = 60/159 (37.74%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D Q+TASS ++ +W + +ARL + + +W A S+WLQVDL ++G++TQG D Q+V S+ I+YS DG ++ +D+ G KVFQGN D+ + + N + I AR ++ +S++G +LR EILGC Sbjct: 268 PLGMKSGHIQDYQVTASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQGKDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLRAEILGC 422
BLAST of Lactadherin vs. Ensembl Medaka
Match: edil3a (EGF like repeats and discoidin domains 3 [Source:NCBI gene;Acc:101165646]) HSP 1 Score: 133.265 bits (334), Expect = 3.625e-33 Identity = 102/332 (30.72%), Postives = 162/332 (48.80%), Query Frame = 3 Query: 138 GPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENRK----SWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYI----KDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILG-----VFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMR 1055 GPLGM G I +QQITASST L+ W ARL N+K +W A W+Q++L ++GV+TQG R ++V S+ ++YS DG + KDD +F+GN D+ + N F I A++++ + H +LR+E+LGC+ C E LG + Y SS + E L +G W A +++QW+Q+D+ P+ +T IIT+G D H +V Y++++SN+ + W Y++ + VF+GN D+++ + N + P AR RI P +W +I +R Sbjct: 102 GPLGMEGGIISNQQITASSTHRALFGLQKW----YPYFARL---NKKGLVNAWTAAENDRWPWIQINLQRRMRVTGVITQGAKRIGSPEYVKSYKVAYSDDGKTWRTYRVKGKDD---DMIFRGNVDNNAPSANSFTPPIEAQYVRIYPQVCRRHCTLRMELLGCELTGCSEPLGMKSGHIQDYQVTASSIFRTLNMDMFTWEPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQG-----------KDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLR 412 HSP 2 Score: 96.6709 bits (239), Expect = 6.375e-21 Identity = 60/159 (37.74%), Postives = 92/159 (57.86%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASS------TELKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDD-YGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 PLGM G I+D Q+TASS ++ +W + +ARL + + +W A S+WLQVDL ++G++TQG D Q+V S+ I+YS DG ++ +D+ G KVFQGN D+ + + N + I AR ++ +S++G +LR EILGC Sbjct: 264 PLGMKSGHIQDYQVTASSIFRTLNMDMFTW----EPGKARLDKQGKVNAWTAGHSDQSQWLQVDLLVPTKVTGIITQGAKDFGHVQFVGSYKIAYSNDGERWNVYQDEKQGKDKVFQGNFDNDTHRKNVIDPPIYARLVRILPWSWYGRITLRAEILGC 418
BLAST of Lactadherin vs. Ensembl Medaka
Match: mfge8b (lactadherin [Source:NCBI gene;Acc:101165726]) HSP 1 Score: 122.865 bits (307), Expect = 2.136e-29 Identity = 93/351 (26.50%), Postives = 165/351 (47.01%), Query Frame = 3 Query: 102 IDADYEKECNT-----------VGPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQK--VFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---GHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 +D D++ C + + LGM G I + QI+ASS L+ W ARL+ + +W A + W+Q+++ + ++G++TQG R A+++ +F ++ S DG + + + G +K VF GN D+ S K N F+ I A++I+ +LR+E++GC+ C E +G+ + + E + H L +G W A N+++W+Q+D+ P IT IIT+G D ++ ++V+ S++ K+W K+ + + +F GN D+N K N F +R+ RI P W E+I +R+ Sbjct: 127 LDGDFKCHCPSPFVGKHCQLRCISLLGMEGGGIAESQISASSVRYSLLGLQRW----GPELARLHKKGLVNAWSAAAHDKNPWIQINMQRKMRLTGIVTQGASRMGSAEFIKAFKVASSLDGKTYTMYRTE-GQRKDHVFVGNVDNDSTKTNLFDPPIIAQYIRIVPVVCRKACTLRMELVGCELNGCSEPMGMKSRLVLDRQITASSSFRTWGLEAFTWHPHFARLDKQGKTNAWTASTNNRSEWLQVDLLSPKKITGIITQGAKDFGSVQFIVSFKVAHSDDGKSWTVVKDETS-----------KTDKIFPGNSDNNVHKKNIFEPAFYSRYVRILPWEWHERITLRM 461 HSP 2 Score: 88.9669 bits (219), Expect = 3.126e-18 Identity = 56/159 (35.22%), Postives = 91/159 (57.23%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM + D+QITASS+ E +W + ARL + + +W A + SEWLQVDL + I+G++TQG D Q++VSF +++S DG ++ +KD+ + K+F GN D+ K N F +R+++ + +H +LR+E+LGC Sbjct: 312 PMGMKSRLVLDRQITASSSFRTWGLEAFTWHPH----FARLDKQGKTNAWTASTNNRSEWLQVDLLSPKKITGIITQGAKDFGSVQFIVSFKVAHSDDGKSWTVVKDETSKTDKIFPGNSDNNVHKKNIFEPAFYSRYVRILPWEWHERITLRMELLGC 466
BLAST of Lactadherin vs. Ensembl Medaka
Match: mfge8b (lactadherin [Source:NCBI gene;Acc:101165726]) HSP 1 Score: 122.865 bits (307), Expect = 2.585e-29 Identity = 93/351 (26.50%), Postives = 165/351 (47.01%), Query Frame = 3 Query: 102 IDADYEKECNT-----------VGPLGMIQGDIKDQQITASSTE-----LKSWRDNCKASQARLYLENR-KSWCAKFKSFSEWLQVDLGTEAVISGVMTQG--RGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQK--VFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQ--PCKEILGVFPYXXXXXXXXXXXXXHRTCTEEY---GHI--LSNKG----WCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRI 1058 +D D++ C + + LGM G I + QI+ASS L+ W ARL+ + +W A + W+Q+++ + ++G++TQG R A+++ +F ++ S DG + + + G +K VF GN D+ S K N F+ I A++I+ +LR+E++GC+ C E +G+ + + E + H L +G W A N+++W+Q+D+ P IT IIT+G D ++ ++V+ S++ K+W K+ + + +F GN D+N K N F +R+ RI P W E+I +R+ Sbjct: 138 LDGDFKCHCPSPFVGKHCQLRCISLLGMEGGGIAESQISASSVRYSLLGLQRW----GPELARLHKKGLVNAWSAAAHDKNPWIQINMQRKMRLTGIVTQGASRMGSAEFIKAFKVASSLDGKTYTMYRTE-GQRKDHVFVGNVDNDSTKTNLFDPPIIAQYIRIVPVVCRKACTLRMELVGCELNGCSEPMGMKSRLVLDRQITASSSFRTWGLEAFTWHPHFARLDKQGKTNAWTASTNNRSEWLQVDLLSPKKITGIITQGAKDFGSVQFIVSFKVAHSDDGKSWTVVKDETS-----------KTDKIFPGNSDNNVHKKNIFEPAFYSRYVRILPWEWHERITLRM 472 HSP 2 Score: 88.5817 bits (218), Expect = 3.504e-18 Identity = 56/159 (35.22%), Postives = 91/159 (57.23%), Query Frame = 3 Query: 141 PLGMIQGDIKDQQITASST------ELKSWRDNCKASQARLYLENRK-SWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGD--GAQWVVSFMISYSTDGTNFHYIKDDYG-SQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGC 587 P+GM + D+QITASS+ E +W + ARL + + +W A + SEWLQVDL + I+G++TQG D Q++VSF +++S DG ++ +KD+ + K+F GN D+ K N F +R+++ + +H +LR+E+LGC Sbjct: 323 PMGMKSRLVLDRQITASSSFRTWGLEAFTWHPH----FARLDKQGKTNAWTASTNNRSEWLQVDLLSPKKITGIITQGAKDFGSVQFIVSFKVAHSDDGKSWTVVKDETSKTDKIFPGNSDNNVHKKNIFEPAFYSRYVRILPWEWHERITLRMELLGC 477
BLAST of Lactadherin vs. Planmine SMEST
Match: SMESG000001686.1 (SMESG000001686.1) HSP 1 Score: 1135.55 bits (2936), Expect = 0.000e+0 Identity = 575/578 (99.48%), Postives = 578/578 (100.00%), Query Frame = 3 Query: 27 LLDFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRINRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 ++DFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYGKIISSGSKGKKKHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIGVLGCKHKGKCGKGFLKVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRR+NRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY Sbjct: 3 IVDFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYGKIISSGSKGKKKHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIGVLGCKHKGKCGKGFLKVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRMNRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 580
BLAST of Lactadherin vs. Planmine SMEST
Match: SMESG000001686.1 (SMESG000001686.1) HSP 1 Score: 1102.81 bits (2851), Expect = 0.000e+0 Identity = 564/578 (97.58%), Postives = 567/578 (98.10%), Query Frame = 3 Query: 27 LLDFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYXXXXXXXXXXXXXHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPNNVYMWWIQNGTVFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIXXXXXXXXXXXXXXXXXVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRINRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 1760 ++DFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYGKIISSGSKGKKKHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPN VFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIGVLGCKHKGKCGKGFLKVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRR+NRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY Sbjct: 3 IVDFFFSNMRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTELKSWRDNCKASQARLYLENRKSWCAKFKSFSEWLQVDLGTEAVISGVMTQGRGDGAQWVVSFMISYSTDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYSFHGHPSLRVEILGCQPCKEILGVFPYGKIISSGSKGKKKHRTCTEEYGHILSNKGWCAKKQNKNQWIQIDIGQPSLITAIITKGRGDSKHPTYVTEYQVSFSNNSKNWYYYKENSESGPN-----------VFKGNEDSNSEKINYLREPFVARFTRIHPINWKEKIGMRIGVLGCKHKGKCGKGFLKVNDVSPCIANIAYKKQAWITMETNKMHKRNIGYSPSERRSQFMKNANKAVDGHTQWEMDADDQQDSTNVRIDRRMNRKQHMRTCTVLQYKTSSNYNPIWYVNLGEQTTVNGVIIYNGNDILFSEKSENRAERDLVENVDKISVFVDQYNSKGTNQFRKTSDLLCGSVTKFNNALSKPKVHISCQQPMVGQFVYIQATGVKHRRRTDFKAILCEVMVY 569
BLAST of Lactadherin vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1) HSP 1 Score: 54.6842 bits (130), Expect = 2.067e-7 Identity = 40/128 (31.25%), Postives = 61/128 (47.66%), Query Frame = 3 Query: 264 SWCAK---FKSFSEWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYS------TDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYS-FHGHPSLRVEILGCQPCKEIL 608 +WC KS SE+LQ+DLG +I V+T+GR G G ++ + I YS +D N+ K+ G QK+ G D+F + I R I+ YS L++++ GC +IL Sbjct: 31 AWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDIL 157
BLAST of Lactadherin vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1) HSP 1 Score: 54.299 bits (129), Expect = 2.492e-7 Identity = 40/128 (31.25%), Postives = 61/128 (47.66%), Query Frame = 3 Query: 264 SWCAK---FKSFSEWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYS------TDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYS-FHGHPSLRVEILGCQPCKEIL 608 +WC KS SE+LQ+DLG +I V+T+GR G G ++ + I YS +D N+ K+ G QK+ G D+F + I R I+ YS L++++ GC +IL Sbjct: 17 AWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDIL 143
BLAST of Lactadherin vs. Planmine SMEST
Match: SMESG000014159.1 (SMESG000014159.1) HSP 1 Score: 54.299 bits (129), Expect = 2.598e-7 Identity = 40/128 (31.25%), Postives = 61/128 (47.66%), Query Frame = 3 Query: 264 SWCAK---FKSFSEWLQVDLGTEAVISGVMTQGR---GDGAQWVVSFMISYS------TDGTNFHYIKDDYGSQKVFQGNRDSFSVKHNYFNDKIRARFIKFHTYS-FHGHPSLRVEILGCQPCKEIL 608 +WC KS SE+LQ+DLG +I V+T+GR G G ++ + I YS +D N+ K+ G QK+ G D+F + I R I+ YS L++++ GC +IL Sbjct: 17 AWCPSNQVEKSLSEYLQIDLGRLTMIKVVLTKGRFAQGSGKEFTPLYQIRYSRNNGSGSDWKNYRKFKEK-GFQKILNGPTDAFIDAFETLDPPIIGRVIRIFPYSNVLQRVCLKLQLFGCIFSNDIL 143 The following BLAST results are available for this feature:
BLAST of Lactadherin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 4
BLAST of Lactadherin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Lactadherin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Lactadherin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Lactadherin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Lactadherin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Lactadherin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Lactadherin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Lactadherin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30024840 ID=SMED30024840|Name=Lactadherin|organism=Schmidtea mediterranea sexual|type=transcript|length=1992bpback to top protein sequence of SMED30024840-orf-1 >SMED30024840-orf-1 ID=SMED30024840-orf-1|Name=SMED30024840-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=571bp MRFLLLSCVICVASVILIDADYEKECNTVGPLGMIQGDIKDQQITASSTEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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