RING-type domain-containing protein

Overview


Name	RING-type domain-containing protein
Smed ID	SMED30024800
Length (bp)	1409

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of RING-type domain-containing protein (SMED30024800) t-SNE clustered cells

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30024800) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RING-type domain-containing protein (SMED30024800) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RING-type domain-containing protein (SMED30024800) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024800

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30024800	SMESG000036117.1 SMESG000036064.1 SMESG000000776.1 SMESG000000765.1 SMESG000000754.1 SMESG000000687.1 SMESG000000587.1	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024800	SMESG000036117.1 SMESG000036064.1 SMESG000000776.1 SMESG000000765.1 SMESG000000754.1 SMESG000000687.1 SMESG000000587.1	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30024800	SMESG000036117.1 SMESG000036064.1 SMESG000000776.1 SMESG000000765.1 SMESG000000754.1 SMESG000000687.1 SMESG000000587.1	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30024800	SMESG000036117.1 SMESG000000754.1 SMESG000000587.1	Contig31191	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30024800	SMESG000036117.1 SMESG000000754.1 SMESG000000587.1	Contig31191	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30024800	SMESG000036117.1 SMESG000036064.1 SMESG000000776.1 SMESG000000765.1 SMESG000000754.1 SMESG000000687.1 SMESG000000587.1	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
dorsal region of the epidermis	SMED30024800	SMESG000036117.1 SMESG000036064.1 SMESG000000776.1 SMESG000000765.1 SMESG000000754.1 SMESG000000687.1 SMESG000000587.1	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: AL136295.10 (novel transcript)

HSP 1 Score: 124.79 bits (312), Expect = 1.002e-29
Identity = 94/338 (27.81%), Postives = 157/338 (46.45%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  677 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 1010

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 124.79 bits (312), Expect = 1.002e-29
Identity = 94/338 (27.81%), Postives = 157/338 (46.45%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  677 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 1010

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Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  677 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 1010

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: AL136295.5 (novel transcript)

HSP 1 Score: 124.79 bits (312), Expect = 1.002e-29
Identity = 94/338 (27.81%), Postives = 157/338 (46.45%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  677 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 1010

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Human
Match: RNF31 (ring finger protein 31 [Source:HGNC Symbol;Acc:HGNC:16031])

HSP 1 Score: 124.405 bits (311), Expect = 1.398e-29
Identity = 94/338 (27.81%), Postives = 157/338 (46.45%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  522 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 855

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BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 59.6918 bits (143), Expect = 3.236e-9
Identity = 47/202 (23.27%), Postives = 82/202 (40.59%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN-HVNDKIKC--PKCNELSCKKCKNKWHENEFCDFTKQN--------GNQNIFQDFSHNLID----------CPKCKAKFY-LDKGGCLHL 987
            +CPLC    P S    +  C  + C+ C + +V E+ +  +  ++ CP C        ++ L+    + ++    TL   Y    +  ++  +A+  WC    C + F  +      ++KC  P C  L C  CK +WH N+ CD  ++           + I +   H   D          CP+CK     +D G C H+
Sbjct:   54 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYV-ELSITENRVEVPCPEC--------SSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHM 246

[Close]

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN-HVNDKIKC--PKCNELSCKKCKNKWHENEFCDFTKQN--------GNQNIFQDFSHNLID----------CPKCKAKFY-LDKGGCLHL 987
            +CPLC    P S    +  C  + C+ C + +V E+ +  +  ++ CP C        ++ L+    + ++    TL   Y    +  ++  +A+  WC    C + F  +      ++KC  P C  L C  CK +WH N+ CD  ++           + I +   H   D          CP+CK     +D G C H+
Sbjct:   54 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYV-ELSITENRVEVPCPEC--------SSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHM 246

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BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 59.3066 bits (142), Expect = 3.682e-9
Identity = 47/202 (23.27%), Postives = 82/202 (40.59%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN-HVNDKIKC--PKCNELSCKKCKNKWHENEFCDFTKQN--------GNQNIFQDFSHNLID----------CPKCKAKFY-LDKGGCLHL 987
            +CPLC    P S    +  C  + C+ C + +V E+ +  +  ++ CP C        ++ L+    + ++    TL   Y    +  ++  +A+  WC    C + F  +      ++KC  P C  L C  CK +WH N+ CD  ++           + I +   H   D          CP+CK     +D G C H+
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYV-ELSITENRVEVPCPEC--------SSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHM 276

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 59.3066 bits (142), Expect = 3.682e-9
Identity = 47/202 (23.27%), Postives = 82/202 (40.59%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN-HVNDKIKC--PKCNELSCKKCKNKWHENEFCDFTKQN--------GNQNIFQDFSHNLID----------CPKCKAKFY-LDKGGCLHL 987
            +CPLC    P S    +  C  + C+ C + +V E+ +  +  ++ CP C        ++ L+    + ++    TL   Y    +  ++  +A+  WC    C + F  +      ++KC  P C  L C  CK +WH N+ CD  ++           + I +   H   D          CP+CK     +D G C H+
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYV-ELSITENRVEVPCPEC--------SSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHM 276

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Match: C17H11.6 (RBR-type E3 ubiquitin transferase [Source:UniProtKB/TrEMBL;Acc:A0A0K3AYH3])

HSP 1 Score: 59.3066 bits (142), Expect = 3.818e-9
Identity = 47/202 (23.27%), Postives = 82/202 (40.59%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN-HVNDKIKC--PKCNELSCKKCKNKWHENEFCDFTKQN--------GNQNIFQDFSHNLID----------CPKCKAKFY-LDKGGCLHL 987
            +CPLC    P S    +  C  + C+ C + +V E+ +  +  ++ CP C        ++ L+    + ++    TL   Y    +  ++  +A+  WC    C + F  +      ++KC  P C  L C  CK +WH N+ CD  ++           + I +   H   D          CP+CK     +D G C H+
Sbjct:   84 ECPLCAAKMPGSAFPKLKGCQHRSCRACLRQYV-ELSITENRVEVPCPEC--------SSYLHPNDIKMLIGDIPTLIEKYEAFSLRRYLMTEADARWCPAPDCGFVFIATKCAACPQLKCQRPDCGTLFCYHCKREWHSNQTCDEARRPEKRKSRGLAFEEIMRTGFHQSADSTLKPGDVKACPRCKTYIVKMDDGSCNHM 276

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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331216)

HSP 1 Score: 112.849 bits (281), Expect = 5.959e-26
Identity = 95/337 (28.19%), Postives = 159/337 (47.18%), Query Frame = 1

Query:  436 ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTS---LYFLSFQEIVNS--DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----DFTKQNG----NQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG-CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXX------PCYKDT------------------GLCTDHFKEYIAALIFK 1317
            +LQ++C LC++ +P+++M +ML C  + CK C K +    I + S +   CP C  PE++   ++      YF +    + S  D  +  ++  K     + +D N  WC   +CS GF  +     ++ CP C  ++C +C+  W   HE   C    ++ ++N      Q + +  + N IDCPKCK ++ L +GGC+H  C +CK EFC  C + F+    C           HAHHP+ C ++LRD    ++  Q+Q   K +N       ++I ++SS +SK         P  K+T                  G+C  H+ EY+A  + K
Sbjct: 2509 MLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCI--QCSSGF-FARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRD----KIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAK 2838

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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331218)

HSP 1 Score: 112.849 bits (281), Expect = 6.056e-26
Identity = 95/337 (28.19%), Postives = 159/337 (47.18%), Query Frame = 1

Query:  436 ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTS---LYFLSFQEIVNS--DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----DFTKQNG----NQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG-CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXX------PCYKDT------------------GLCTDHFKEYIAALIFK 1317
            +LQ++C LC++ +P+++M +ML C  + CK C K +    I + S +   CP C  PE++   ++      YF +    + S  D  +  ++  K     + +D N  WC   +CS GF  +     ++ CP C  ++C +C+  W   HE   C    ++ ++N      Q + +  + N IDCPKCK ++ L +GGC+H  C +CK EFC  C + F+    C           HAHHP+ C ++LRD    ++  Q+Q   K +N       ++I ++SS +SK         P  K+T                  G+C  H+ EY+A  + K
Sbjct: 2468 MLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCI--QCSSGF-FARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRD----KIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAK 2797

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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331220)

HSP 1 Score: 112.849 bits (281), Expect = 6.164e-26
Identity = 95/337 (28.19%), Postives = 159/337 (47.18%), Query Frame = 1

Query:  436 ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTS---LYFLSFQEIVNS--DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----DFTKQNG----NQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG-CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXX------PCYKDT------------------GLCTDHFKEYIAALIFK 1317
            +LQ++C LC++ +P+++M +ML C  + CK C K +    I + S +   CP C  PE++   ++      YF +    + S  D  +  ++  K     + +D N  WC   +CS GF  +     ++ CP C  ++C +C+  W   HE   C    ++ ++N      Q + +  + N IDCPKCK ++ L +GGC+H  C +CK EFC  C + F+    C           HAHHP+ C ++LRD    ++  Q+Q   K +N       ++I ++SS +SK         P  K+T                  G+C  H+ EY+A  + K
Sbjct: 2456 MLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCI--QCSSGF-FARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRD----KIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAK 2785

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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: LUBEL (gene:FBgn0031857 transcript:FBtr0331221)

HSP 1 Score: 112.464 bits (280), Expect = 6.922e-26
Identity = 95/337 (28.19%), Postives = 159/337 (47.18%), Query Frame = 1

Query:  436 ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTS---LYFLSFQEIVNS--DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----DFTKQNG----NQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG-CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXX------PCYKDT------------------GLCTDHFKEYIAALIFK 1317
            +LQ++C LC++ +P+++M +ML C  + CK C K +    I + S +   CP C  PE++   ++      YF +    + S  D  +  ++  K     + +D N  WC   +CS GF  +     ++ CP C  ++C +C+  W   HE   C    ++ ++N      Q + +  + N IDCPKCK ++ L +GGC+H  C +CK EFC  C + F+    C           HAHHP+ C ++LRD    ++  Q+Q   K +N       ++I ++SS +SK         P  K+T                  G+C  H+ EY+A  + K
Sbjct: 2415 MLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCI--QCSSGF-FARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRD----KIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAK 2744

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BLAST of RING-type domain-containing protein vs. Ensembl Fly
Match: ari-1 (gene:FBgn0017418 transcript:FBtr0089508)

HSP 1 Score: 51.2174 bits (121), Expect = 1.381e-6
Identity = 42/213 (19.72%), Postives = 86/213 (40.38%), Query Frame = 1

Query:  364 SEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHENEFCDFTKQ-----NGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHL 987
            + VI P++  +A+   T  +  ++     C +C    P   M   L C  +FC  C+ +++   I+     + +  +    +    + ++  L       +D  +R  Y +   + F++ +    WC +  C+Y   +      ++ C KC  + C  C   WH+   C + K+     + +       + N  +CP+C      D GGC H+
Sbjct:  109 AHVINPFNATEAIKQKTSRSQCEE-----CEICFSQLPPDSMAG-LECGHRFCMPCWHEYLSTKIVAEGLGQTISCAAHGCDILVDDVTVANLV------TDARVRVKYQQLITNSFVECNQLLRWCPSVDCTYAVKVPYAEPRRVHC-KCGHVFCFACGENWHDPVKCRWLKKWIKKCDDDSETSNWIAANTKECPRCSVTIEKD-GGCNHM 307

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-181m9.8 (si:dkey-181m9.8 [Source:ZFIN;Acc:ZDB-GENE-070912-399])

HSP 1 Score: 114.39 bits (285), Expect = 1.000e-26
Identity = 101/365 (27.67%), Postives = 166/365 (45.48%), Query Frame = 1

Query:  346 DKQEVYSEVIE-------PYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTSLYFLSF---QEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIK--CPKCNELSCKKCKNKW---HENEFCDFTK--------QNGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG--CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFE-------KPKNS----TLTLCDIEIYNXXXXX-----XXXXXPCYKDTGLCTDHFKEYIAALI 1311
            DK E++  ++          DV++A+     +      L   CP+C +    ++M  M +C+C FC++C+K +   VI   +    +CP C  P++   ++  ++ + S    Q     D  +  ++  K     +    N  WC +  C +G     H  D+++  CP C + +C KCK  W   HE   C+  K        +  N  + Q  S N IDCPKCK +F+L +GGCLH  C +C+HEFC  C + F ++G  C           HAHHP+ C Y LRD  V  L + +Q +         PK+     +  +C +  + ++         + + P Y  +G CT H+KE +  LI
Sbjct:  176 DKAEMFRSIMSLEGCSFSSTDVLEAVQSCRDLPSALKYLCHDCPICQEQVSFNRMVTMTHCSCTFCESCFKKYFSSVIKEKNIVHAVCPLCNLPDVRGGRREDTMEYFSLLDTQIRYYLDSQIHELFQRKLRDRALQEMPNFRWCAH--CCFGL---LHEADRLRMDCPSCGKSTCFKCKRPWAPQHEGISCEKFKEWEQLNSPEYQNSRLEQLLSRNKIDCPKCKFRFFLARGGCLHFRCTQCQHEFCGGCSQPF-KQGSTCNFSIECAAKGLHAHHPRNCLYHLRDWSVPRLRTLLQRYGVSHPLMFSPKHPMGRHSKGICGVMEFQETGAVKEEACGRQAFPEY--SGYCTLHYKEVLVELI 532

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: FO834800.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:100334178])

HSP 1 Score: 110.153 bits (274), Expect = 3.607e-25
Identity = 78/273 (28.57%), Postives = 136/273 (49.82%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ 1161
            DV+QA+ +    + I+ +L ++CP+CL  FP SKM ++  C C  C  C++      + +     ++CP C E +         + S  +I   D   + VY  + K+++E  + +D   +WC++  CSYGF I +    K+ C +C +  C +CK  W          +F  + ++N      Q +      N I CP C+ ++ L +GGC+H +C +C+++FC  C   F    C    C +    HAHHP+ C ++LRD +   L++ +Q
Sbjct:  665 DVVQAVRESPDRDFIRRVLNKECPICLSVFPHSKMRSLTSCQCSVCCGCFQQHFTIAVRDKHIRDMVCPVCTEPDINDPEHLNSYFSTLDIQLRDCLEQEVYELFHKKLTEQALIKDPKFLWCSH--CSYGF-IYDDDQLKVTCSQCRKSFCAQCKKTWEPQHMGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPF-HTTCAVNQCTV-TGLHAHHPRDCLFYLRDWEPARLQALLQ 932

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: FO834800.2 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:108179742])

HSP 1 Score: 78.9518 bits (193), Expect = 4.406e-16
Identity = 65/239 (27.20%), Postives = 114/239 (47.70%), Query Frame = 1

Query:  487 MHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ 1161
            M ++  C C  C  C++      + +     ++CP C E +         + S  +I   D   + VY  + K+++E  + +D   +WC++  CSYGF I +    K+ C +C +  C +CK  W   H    C+    + ++N      Q +      N I CP C+ ++ L +GGC+H +C +C+++FC  C   F    C    C +    HAHHP+ C ++LRD +   L++ +Q
Sbjct:    1 MRSLTSCQCSVCCGCFQQHFTIAVRDKHIRDMVCPVCTEPDINDPEHLNSYFSTLDIQLRDCLEQEVYELFHKKLTEQALIKDPKFLWCSH--CSYGF-IYDDDQLKVTCSQCRKSFCAQCKKTWEPQHMGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPF-HTTCAVNQCTV-TGLHAHHPRDCLFYLRDWEPARLQALLQ 234

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: rnf144ab (ring finger protein 144ab [Source:NCBI gene;Acc:437000])

HSP 1 Score: 57.7658 bits (138), Expect = 7.944e-9
Identity = 48/197 (24.37%), Postives = 81/197 (41.12%), Query Frame = 1

Query:  424 DIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCP--SCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN---HVNDKIKCPKCNELSCKKCKNKWHENEFCD--------FTKQNGNQNI-FQDFSHNLIDCPKCKAKFYLDKG 972
            D+  +L   C LCL  FPL +M  +  C C FC  C K +V  +I       + CP  +CP+     +N         E + + E +++ Y   +    +  D    WC +  C     ++     +   ++CP+C+   C  C+   H  + C            +NG+ N+  Q+    +  CPKCK     D+G
Sbjct:   13 DLAPLL--SCKLCLGEFPLEQMTTISQCQCIFCSLCLKQYVELLIKEGLETAISCPDSTCPKQGHLLENEI-------ECMVAGEVMQH-YKRLQFEREVLLDPCRTWCPSSSCQAVCQLNEAEVQLPQPVQCPECSLRFCSACRADCHTGQACQEMLPITTFLPGENGSSNLKSQEDEAPIKRCPKCKVYIERDEG 199

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-278j3.3 (si:ch211-278j3.3 [Source:ZFIN;Acc:ZDB-GENE-041014-147])

HSP 1 Score: 58.151 bits (139), Expect = 1.257e-8
Identity = 49/206 (23.79%), Postives = 82/206 (39.81%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQ------NGNQNIFQDFSHN--------LIDCPKCKAKFY-LDKGGCLHLN 990
            +CPLCL   P +    +  C  + C  C + ++R  I  S    + CP CPE        +L     + I++ D  L   + E ++  F+  D +T WC    CSY             C +C +LSC +          C+  WH ++ CD  ++      +G  ++   +  N        +  CP+C A     + G C  +N
Sbjct:  111 ECPLCLLSQPRAHFPRLSSCQHRACTDCLRQYLRIEISESRVG-IACPQCPE--------ALALPDVRAILD-DGALLERFEEFQLRRFLAADPDTRWCPAPDCSYAV-------IAYGCAECPKLSCGREGCETEFCYHCRQLWHPDQTCDQARRQRARHTSGANDVSTLYVFNEEPGDAEEIKPCPRCGAYIMKTNDGSCNRMN 299

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 129.798 bits (325), Expect = 2.122e-31
Identity = 99/334 (29.64%), Postives = 165/334 (49.40%), Query Frame = 1

Query:  376 EPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHE-------NEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELES--QIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            E  DV++A+ +    + IK +L ++C +C    P +KM ++  C C  C  C++      +       ++CP+C E   + +   L++ S  +I+  D    + Y  + K+++E  + +D   +WCT+  CS+GF I       +KCP+C    C+KCK  W E       ++F ++ ++N  +   Q  +     N I CP CK  + L +GGC+H  C +C+H+FC  C   F  R  C   +C +  S HAHHP+ C ++LRD DV  L+   Q+    + K + L  C + +  K        + C K T     GLC  H+KEY+ + I
Sbjct:  588 ELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLSEVKGTLLCGCRV-MEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRI 917

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 128.257 bits (321), Expect = 5.715e-31
Identity = 95/329 (28.88%), Postives = 160/329 (48.63%), Query Frame = 1

Query:  376 EPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHE-------NEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELES--QIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCTDHFKEYIAALI 1311
            E  DV++A+ +    + IK +L ++C +C    P +KM ++  C C  C  C++      +       ++CP+C E   + +   L++ S  +I+  D    + Y  + K+++E  + +D   +WCT+  CS+GF I       +KCP+C    C+KCK  W E       ++F ++ ++N  +   Q  +     N I CP CK  + L +GGC+H  C +C+H+FC  C   F  R  C   +C +  S HAHHP+ C ++LRD DV  L+   Q+    + K     +   EI +     +          GLC  H+KEY+ + I
Sbjct:  589 ELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLSEVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRI 914

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 127.872 bits (320), Expect = 7.553e-31
Identity = 95/329 (28.88%), Postives = 160/329 (48.63%), Query Frame = 1

Query:  376 EPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHE-------NEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELES--QIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCTDHFKEYIAALI 1311
            E  DV++A+ +    + IK +L ++C +C    P +KM ++  C C  C  C++      +       ++CP+C E   + +   L++ S  +I+  D    + Y  + K+++E  + +D   +WCT+  CS+GF I       +KCP+C    C+KCK  W E       ++F ++ ++N  +   Q  +     N I CP CK  + L +GGC+H  C +C+H+FC  C   F  R  C   +C +  S HAHHP+ C ++LRD DV  L+   Q+    + K     +   EI +     +          GLC  H+KEY+ + I
Sbjct:  535 ELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLSEVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRI 860

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 127.872 bits (320), Expect = 8.537e-31
Identity = 95/329 (28.88%), Postives = 160/329 (48.63%), Query Frame = 1

Query:  376 EPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHE-------NEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELES--QIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCTDHFKEYIAALI 1311
            E  DV++A+ +    + IK +L ++C +C    P +KM ++  C C  C  C++      +       ++CP+C E   + +   L++ S  +I+  D    + Y  + K+++E  + +D   +WCT+  CS+GF I       +KCP+C    C+KCK  W E       ++F ++ ++N  +   Q  +     N I CP CK  + L +GGC+H  C +C+H+FC  C   F  R  C   +C +  S HAHHP+ C ++LRD DV  L+   Q+    + K     +   EI +     +          GLC  H+KEY+ + I
Sbjct:  539 ELQDVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQVSKLSEVKGGCRVMEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRI 864

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Match: rnf31 (ring finger protein 31 [Source:NCBI gene;Acc:100036616])

HSP 1 Score: 118.627 bits (296), Expect = 9.466e-28
Identity = 98/338 (28.99%), Postives = 161/338 (47.63%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHE-------NEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVN-----ELESQIQDFEKPKNSTLTL----CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+ +    + IK +L ++C +C    P +KM ++  C C  C  C++      +       ++CP+C E   + +   L++ S  +I+  D    + Y  + K+++E  + +D   +WCT+  CS+GF I       +KCP+C    C+KCK  W E       ++F ++ ++N  +   Q  +     N I CP CK  + L +GGC+H  C +C+H+FC  C   F  R  C   +C +  S HAHHP+ C ++LRD DV           +Q    P   T T     C + +  K        + C K T     GLC  H+KEY+ + I
Sbjct:  639 DVVEAVRESQDRDFIKRMLTQECAVCGWELPRNKMRSLTSCECCICPDCFRMHFTVAVKEKHIRDMICPACEEPEISDEGELLHYFSTLDILLRDTLEVDAYDLFHKKLTERTLMKDPKFLWCTH--CSFGF-IYERDQLDVKCPQCQCSFCRKCKRPWEEQHRSLNCDDFQNWKRENDAEYQAQGLAVYLLENGITCPHCKFSYALARGGCMHFICSQCRHQFCSGCYNTFHQRNKCTVPSCTVRMSLHAHHPRDCLFYLRDWDVTRLQRLLQMLLVQFNTDPPAGTQTAPGGGCRV-MEQKEIPDGLRDEACGKITPPGYAGLCESHYKEYLVSRI 972

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 123.635 bits (309), Expect = 1.473e-29
Identity = 92/338 (27.22%), Postives = 159/338 (47.04%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  ++ C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C + NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + +  K   +    + C K+T     GLC  H+KEY+ +LI
Sbjct:  517 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRV-MEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLI 850

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 123.635 bits (309), Expect = 1.596e-29
Identity = 92/338 (27.22%), Postives = 159/338 (47.04%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  ++ C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C + NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + +  K   +    + C K+T     GLC  H+KEY+ +LI
Sbjct:  671 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRV-MEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLI 1004

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf19b (ring finger protein 19B [Source:MGI Symbol;Acc:MGI:1922484])

HSP 1 Score: 62.003 bits (149), Expect = 1.154e-9
Identity = 48/204 (23.53%), Postives = 76/204 (37.25%), Query Frame = 1

Query:  451 CPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQNGNQNIFQDFSH-------------NLIDCPKCKAKFY-LDKGGCLHLN 990
            CPLCL   P  +   +L C  + C+ C + ++R  I  S    + CP C E      +  L          +D  L + Y E  +  ++  D +  WC    C Y             C  C +L+C++          CK  WH N+ CD  +Q   Q +     H             ++  CP+C A    ++ G C H+ 
Sbjct:  116 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSE-RLNPHDIRLLL--------ADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVI-------AYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSAYIIKMNDGSCNHMT 302

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf19b (ring finger protein 19B [Source:MGI Symbol;Acc:MGI:1922484])

HSP 1 Score: 61.6178 bits (148), Expect = 1.327e-9
Identity = 48/205 (23.41%), Postives = 76/205 (37.07%), Query Frame = 1

Query:  451 CPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQNGNQNIFQDFSH--------------NLIDCPKCKAKFY-LDKGGCLHLN 990
            CPLCL   P  +   +L C  + C+ C + ++R  I  S    + CP C E      +  L          +D  L + Y E  +  ++  D +  WC    C Y             C  C +L+C++          CK  WH N+ CD  +Q   Q +     H              ++  CP+C A    ++ G C H+ 
Sbjct:  116 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSE-RLNPHDIRLLL--------ADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVI-------AYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT 303

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Match: Rnf31 (ring finger protein 31 [Source:MGI Symbol;Acc:MGI:1934704])

HSP 1 Score: 55.8398 bits (133), Expect = 2.232e-9
Identity = 33/80 (41.25%), Postives = 48/80 (60.00%), Query Frame = 1

Query:  928 IDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD 1164
            IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C + NC +  S H HHP+ C ++LRD     L+  +Q 
Sbjct:    3 IDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQG 82

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q96EP0|RNF31_HUMAN (E3 ubiquitin-protein ligase RNF31 OS=Homo sapiens OX=9606 GN=RNF31 PE=1 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 4.812e-29
Identity = 94/338 (27.81%), Postives = 157/338 (46.45%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  +  C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C E NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + I  K        + C K+T     GLC  H+KEY+ +LI
Sbjct:  677 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPHNRMQALTSCECTICPDCFRQHFTIALKEKHITDMVCPACGRPDLTDDTQLLSYFSTLDIQLRESLEPDAYALFHKKLTEGVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRMNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPEPNCRVKKSLHGHHPRDCLFYLRDWTALRLQKLLQDNNVMFNTEPPAGARAVPGGGCRV-IEQKEVPNGLRDEACGKETPAGYAGLCQAHYKEYLVSLI 1010

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q924T7|RNF31_MOUSE (E3 ubiquitin-protein ligase RNF31 OS=Mus musculus OX=10090 GN=Rnf31 PE=1 SV=2)

HSP 1 Score: 123.635 bits (309), Expect = 1.117e-28
Identity = 92/338 (27.22%), Postives = 159/338 (47.04%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHEN-------EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF-VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD------FEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV++A+        ++ +L ++C +C    P ++M  ++ C C  C  C++      +       ++CP+C   +       L + S  +I   +    + Y  + K+++E  + RD   +WC   +CS+GF I      +  CP+C++  C +CK +W E        +F ++ + N      Q +      N IDCPKCK  + L +GGC+H +C +C+H+FC  C   F  +  C + NC +  S H HHP+ C ++LRD     L+  +QD       E P  +       C + +  K   +    + C K+T     GLC  H+KEY+ +LI
Sbjct:  671 DVVEAVRHSQDRAFLRRLLAQECAVCGWALPRNRMQALISCECTICPECFRQHFTIALKEKHITDMVCPACGRPDLTDDAQLLSYFSTLDIQLRESLDPDAYALFHKKLTEAVLMRDPKFLWCA--QCSFGF-IYEREQLEATCPQCHQTFCVRCKRQWEEQHRGRSCEDFQNWKRTNDPEYQAQGLAMYLQENGIDCPKCKFSYALARGGCMHFHCTQCRHQFCSGCYNAFYAKNKCPDPNCKVKKSLHGHHPRDCLFYLRDWTAARLQKLLQDNNVMFNTEPPAGTRAVPGGGCRV-MEQKEVHSGFRDEACGKETPPGYAGLCQAHYKEYLVSLI 1004

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8IPJ3|LUBEL_DROME (E3 ubiquitin-protein ligase lubel OS=Drosophila melanogaster OX=7227 GN=LUBEL PE=1 SV=2)

HSP 1 Score: 112.849 bits (281), Expect = 5.973e-25
Identity = 95/337 (28.19%), Postives = 159/337 (47.18%), Query Frame = 1

Query:  436 ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTS---LYFLSFQEIVNS--DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----DFTKQNG----NQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREG-CKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXX------PCYKDT------------------GLCTDHFKEYIAALIFK 1317
            +LQ++C LC++ +P+++M +ML C  + CK C K +    I + S +   CP C  PE++   ++      YF +    + S  D  +  ++  K     + +D N  WC   +CS GF  +     ++ CP C  ++C +C+  W   HE   C    ++ ++N      Q + +  + N IDCPKCK ++ L +GGC+H  C +CK EFC  C + F+    C           HAHHP+ C ++LRD    ++  Q+Q   K +N       ++I ++SS +SK         P  K+T                  G+C  H+ EY+A  + K
Sbjct: 2509 MLQQECELCMNSYPMNQMVSMLKCLHKCCKQCAKSYFTVQITDRSINDCSCPFCKLPELSNEAQHEDEHLEYFSNLDIFLKSILDNDVHELFQRKLRDRSLLQDPNFKWCI--QCSSGF-FARPKQKRLICPDCGSVTCAQCRKPWERQHEGSSCEAYLEWKRENDPELQAQGVQEHLAQNGIDCPKCKFRYSLARGGCMHFTCTQCKFEFCYGCARPFMMGAKCTVSTYCAKLGLHAHHPRNCLFYLRD----KIPLQLQFLLKEQNVKFDTEPMQIKDESSSSSKARAQARCPIPLQKETPQGLVDTVCNTEVPDKHAGMCRTHYVEYLAGKVAK 2838

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|A2A7Q9|RN19B_MOUSE (E3 ubiquitin-protein ligase RNF19B OS=Mus musculus OX=10090 GN=Rnf19b PE=1 SV=2)

HSP 1 Score: 61.6178 bits (148), Expect = 9.285e-9
Identity = 48/205 (23.41%), Postives = 76/205 (37.07%), Query Frame = 1

Query:  451 CPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQNGNQNIFQDFSH--------------NLIDCPKCKAKFY-LDKGGCLHLN 990
            CPLCL   P  +   +L C  + C+ C + ++R  I  S    + CP C E      +  L          +D  L + Y E  +  ++  D +  WC    C Y             C  C +L+C++          CK  WH N+ CD  +Q   Q +     H              ++  CP+C A    ++ G C H+ 
Sbjct:  116 CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSE-RLNPHDIRLLL--------ADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVI-------AYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT 303

[Close]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZMZ0|RN19B_HUMAN (E3 ubiquitin-protein ligase RNF19B OS=Homo sapiens OX=9606 GN=RNF19B PE=1 SV=2)

HSP 1 Score: 61.6178 bits (148), Expect = 9.868e-9
Identity = 48/206 (23.30%), Postives = 77/206 (37.38%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQNGNQNIFQDFSH--------------NLIDCPKCKAKFY-LDKGGCLHLN 990
            +CPLCL   P  +   +L C  + C+ C + ++R  I  S    + CP C E      +  L          +D  L + Y E  +  ++  D +  WC    C Y             C  C +L+C++          CK  WH N+ CD  +Q   Q +     H              ++  CP+C A    ++ G C H+ 
Sbjct:  118 ECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESRV-PISCPECSE-RLNPHDIRLLL--------ADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVI-------AYGCASCPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCSAYIIKMNDGSCNHMT 306

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: A0A2T7NIC0 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19059 PE=4 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.510e-30
Identity = 102/342 (29.82%), Postives = 167/342 (48.83%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSEF-IDRDANTMWCTNDRCSYGFDISNHVNDKIK--CPKCNELSCKKCKNKWHEN-------EFCDFTKQNGNQN----IFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGC--KEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFE------KPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALIFKKN 1323
            DV++A+ +          L ++C +C   +P+SK+ N+ +C C+ C  C K     VI         CP C + +   +     +++F  ++   +  + VY  +E ++ ++ + +D +  WC +  C  GF I++  + ++K  CP C++ +C +CK +W E        +F  +   N   N    + +    N IDCP CK ++ L KGGC+H  C +C HEFC  C + F + G   + +NC M N  HAHHP+ C ++LRD DV  L+  +Q+         P N   T     I  K   + K  + C KD+     GLC  H+KEY+  LI K N
Sbjct: 1448 DVVEAVRNCEDKRSALVYLMQECQICFSHYPMSKIRNLNFCQCKICSDCLKQNFEVVIREKHVRHWTCPLCSKPDLNDEELGSEYINFLGMLLQMQVDKEVYDLFETKVRDWHLQKDPHFRWCAH--CGNGF-IADGGDRQLKMVCPHCSQKTCYQCKKQWEEQHEGVTCEQFAQWKIDNDPNNQAVGLARHLEENGIDCPSCKMRYALAKGGCMHFKCPQCGHEFCSGCCQPFYQRGMCNRLKNCKM-NGLHAHHPRDCFFYLRDCDVQHLQVLLQNANVEFNTVPPANQEETSRCPVIEQKEFDSGKRDESCGKDSGDGLAGLCLLHYKEYLVGLINKNN 1785

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: H2ZW95 (Uncharacterized protein OS=Latimeria chalumnae OX=7897 GN=RNF31 PE=4 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 8.232e-30
Identity = 101/338 (29.88%), Postives = 168/338 (49.70%), Query Frame = 1

Query:  382 YDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSE-FIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HEN----EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ------DFEKPKNSTLTL---CDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            +DV++A+      + IK +L ++C +C   FP ++M ++  C C  C  C+K +    +   +   L+CP C +   + +   L + S  +I   D   ++ Y  + K+++E  +  D   +WC++  CS+GF I +    K+ C +C +  C KCK  W   H+     EF ++ ++N      Q +      N I CP CK  + L +GGC+H NC +C+HEFC  C   F +  C  +NC M  + HAHHP+ C ++LRD DV  L+  ++      + E P  +       C + +  K   +    +PC K T     GLC  H+KEY+ +LI
Sbjct:  692 HDVVEAVKQSHDKHFIKRMLSQECAVCFYSFPRNRMQSLTSCECTICPDCFKQYFTITVKEKNIKDLVCPQCSKPEISDEGELLNYFSTLDIQLRDCLDKDAYDLFHKKLTERTLMNDPKFVWCSH--CSFGF-IYDGDQLKVTCLQCKKSFCIKCKRPWEVQHQGITCEEFQNWKRENDPEYQAQGLAAYLKENGIICPHCKFAYALARGGCMHFNCSQCRHEFCSGCYNTFAKNDCTFKNCTMGKTLHAHHPRDCLFYLRDWDVARLQVLLKKDGVNFNMEPPHGTQAAPGGGCRV-LEQKELPSGVKDEPCAKVTPAGYAGLCISHYKEYLVSLI 1025

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: M3ZQS2 (Ring finger protein 31 OS=Xiphophorus maculatus OX=8083 GN=RNF31 PE=4 SV=2)

HSP 1 Score: 133.65 bits (335), Expect = 1.535e-29
Identity = 99/333 (29.73%), Postives = 160/333 (48.05%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSEF-IDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDF-----EKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            DV+QA+ +      I+ +L  +CP+CL  FP SKM ++  C C  C  C++      + +     ++CP+C E +         + S  +I   D     VY  + K+++E  + +D   +WC +  C+ GF I++    K+ CP C +  C +CK  W   H++  C+    + ++N      Q +      N I CP+CK ++ L KGGC+H  C +C+H+FC  C   + +  CK   C  P   HAHHP+ C ++LRD D + L++ +Q         P N T T     +  K         PC   T     GLC  H++EY+ +LI
Sbjct:  729 DVVQAVKESQDREFIRRLLNTECPVCLSIFPRSKMQSLTSCQCSVCHECFRQHFTIAVRDKHIRDMVCPACSEPDINDPEQLDSYFSTLDIQLRDCLEHEVYELFHKKLTEHALMKDPKFLWCCH--CTSGF-INDGNQLKVTCPSCRKSFCAQCKKPWEPQHQDVSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPECKFQYALTKGGCMHFTCSQCRHQFCSGCNNPYYKMECKIPQCKFPG-LHAHHPRDCLFYLRDWDADRLQALLQRSGVAFNTDPSNETQTDSCGVMEQKDEGGQPADSPCGLQTQPGQAGLCMKHYREYLVSLI 1057

[Close]

BLAST of RING-type domain-containing protein vs. TrEMBL
Match: V4A3V4 (RING-type domain-containing protein (Fragment) OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_52443 PE=4 SV=1)

HSP 1 Score: 130.568 bits (327), Expect = 2.195e-29
Identity = 124/417 (29.74%), Postives = 191/417 (45.80%), Query Frame = 1

Query:  172 ISDKAKRQKLSKSLSNIAEINDTDQYDDI---YSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYS----EVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIV---NSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCDFTKQ-----NGNQNIFQDFSH---NLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPM---PNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTL----TLCDIEIYNXXXXXXXXXXPCYKD-----TGLCTDHFKEYIAALIFKKN 1323
            I  K  +  L   +  + E  D  +Y DI    SN R  RT  + ++      G  +       E  S    E+    DVI+A  +          LQ++C +C   FP++K+ ++  C C+ C  C K      + + +  +  CP C   N A  +T+  +L+F  I+     DE  ++++ +K     I +DAN  WC +  C  GF I       + CP C + +C +CK +W   HEN  C+  +Q     + N   F   +H   N IDCP CK ++ L KGGC+H  C +C HEFC  C + F  E      CP+       H HHP+ C +FLRD + + L+  +Q   K  N+ +    + C +    + S +S   + C K+      GLC DH+KEY+  LI K N
Sbjct:   63 IETKLNQIALQPFMDRVWEDEDGSEYSDICNSVSNSR--RTRMVFMEGKLKSWGRAETVIKIVDEELSKSCLEMSSLEDVIEACRNCLGFKTSLGYLQQECEICYTKFPMNKITSLNICQCKLCIECMKQHFEYCVKDMNVKRWSCPVCSRPNMADYDTAQNYLAFLTILIRNYCDEPTQDLFDKKANLWSIQQDANFRWCAH--CETGF-IYQGNQLCMTCPNCYKKTCFRCKKEWEIQHENITCEEFEQWKYDNDPNNQAFGLANHLKENGIDCPSCKMRYSLSKGGCMHFTCPECSHEFCSGCCQPFYHEN----TCPLECVGKGLHCHHPRDCFFFLRDEEPSTLQELLQMHAKSFNTEVSESSSGCPVMEQKERSHSSNYDEACGKEVKEGWAGLCIDHYKEYLVGLINKHN 470

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BLAST of RING-type domain-containing protein vs. TrEMBL
Match: V9KFD6 (RING finger protein 31 OS=Callorhinchus milii OX=7868 PE=2 SV=1)

HSP 1 Score: 132.109 bits (331), Expect = 3.838e-29
Identity = 102/337 (30.27%), Postives = 160/337 (47.48%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY---YEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HEN----EFCDFTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQF--VREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ----DF--EKPKNSTLTLCD-IEIYNXXXXXXXXXXPCYKD-----TGLCTDHFKEYIAALI 1311
            DV+ +  +    + IK +L   CP+C + FP  KM ++  C C  C  C+K+    ++       L+CP C +    +++  + + S  ++   D   + VY   ++K +   + +D    WC  + CS GF I +    ++ CP+C    C KC   W   H+N    EF D+ + N      Q +      N I CP CK ++ L KGGC+H  C  C+HEFC  C   F  +++ C + NC +  + HAHHP+ C ++LRD  V  L+S ++    DF  E PK +     D   +  +         PC KD      GLC  H+KEY+  LI
Sbjct:  336 DVVDSAKESQDKSFIKRMLSHPCPICFEMFPRHKMQSLTSCECLMCSGCFKEHFTLIVKERHIKDLVCPICGKPEIDEESELINYFSTLDVQLRDCLEKEVYSLFHKKLIERTLMKDPKFKWC--NHCSNGF-IYDGNQLRVTCPQCYHSFCFKCNRPWESQHQNISCDEFQDWKRLNDPEYQAQGLAAYLQDNGIACPGCKFRYALAKGGCMHFTCYFCRHEFCSGCYNTFYGLKKVCPDGNCRLLKALHAHHPRDCLFYLRDWSVERLQSLLKNNKVDFNTEPPKGAQTVPGDKCRVMEQKDTQGNAEVPCSKDAPAGHAGLCLTHYKEYLVWLI 669

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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000018785.2 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:103042649])

HSP 1 Score: 127.487 bits (319), Expect = 7.119e-31
Identity = 119/454 (26.21%), Postives = 193/454 (42.51%), Query Frame = 1

Query:   37 NNLQKLVKQISRMGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKK----NEPRIGYRDGPFLDKQEVYSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTSLYF-LSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC-DFTK-------QNGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ------DFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCY-----KDTGLCTDHFKEYIAALI 1311
             N QK V  I R     N+ ++++  + + F  ++   K               L + L      N   +   IY N   +  + +  +     N P  G         QE  +E     DVIQA+ +    + I  IL+++C +C   FP  KM  + +C C  C  C+       + +     ++CP C  PE+N  +   + +F L  Q  +N +  + +++ +K M   + +D   +WC +  C+ GF I      K+ C  C +  C KCK  W   HE   C DF K       +   Q +      N I CP CK ++ L KGGC+H  C +C++EFC  C   F ++ C    C +   FHAHHP+ C Y+LRD +   L++ +Q      + + P  +   LC   +  +          C         GLC  H++EY+ +LI
Sbjct:  545 GNTQKAVANILR-----NRAEKLRLLRTLGFVDRLACEKALSMSGGDLDGALSHLQRPLLEHFHQNIWKKQPQIYFNINHQDKDRLYRRLLGLYNLPSWGRSQMALTLLQEPDAEY-SVEDVIQAVREHHDKDFINRILKKECQICYASFPQRKMQALTFCQCSMCSECFIQHFTVALRDKHIRDMVCPVCEEPEINDPEALETYFFTLDVQLRLNLEPEVYDLFGKKLMEHTLKKDPKFLWCCH--CTNGF-IYEKDELKVTCQNCRKSFCSKCKKAWEDQHEGLTCNDFQKWKRENDPEYQKQGLVGFLRENGIKCPSCKFQYALAKGGCMHFTCSQCRYEFCCGCNNPFHKKPCPGNQC-ISKGFHAHHPRDCLYYLRDWEPVRLQALLQKHKVEFNTDHPDGTGNGLCG--VMEQKEGGQALDDACGIQVEEGHAGLCDKHYREYLVSLI 986

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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000014446.2 (ring finger protein 31 [Source:NCBI gene;Acc:103030581])

HSP 1 Score: 121.709 bits (304), Expect = 5.434e-29
Identity = 95/342 (27.78%), Postives = 165/342 (48.25%), Query Frame = 1

Query:  379 PY---DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKKNTSLYF----LSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ------DFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            PY   DV+QA+ +    + I+ +L ++CP+CL  FP SKM ++  C C  C  C+K      + +     ++CP C  P++N  +   S YF    +  +E V  +  +  ++++K   + + +D   +WC++  CSYGF I +    K+ C +C    C +CK  W   H    C+    + ++N      Q +      N I CP C+ ++ L +GGC+H +C +C+++FC  C   F    C    C +    HAHHP+ C ++LRD +   L++ +Q      + +    +   +C + I  K     +    C   T     GLC  H++EY+ +LI
Sbjct:  672 PYTLEDVVQAVRESHDRDFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCSGCFKQHFTIAVRDKHIRDMVCPVCWEPDINNPEHLNS-YFSTLDIQLRECVEPE--VYELFHKKLTEQALIKDPKFLWCSH--CSYGF-IYDGDQLKVTCLQCRNSFCAQCKKPWEAQHNGLSCEQFQLWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALARGGCMHFSCSQCRYQFCSGCNNPF-HTTCAVAQCSV-TGLHAHHPRDCLFYLRDWEPARLQALLQKNGVAYNTDTAPGTQTGVCGV-IEQKDEGPRQTDSACGAQTQPGQAGLCEKHYREYLVSLI 1004

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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: si:dkey-181m9.8 (E3 ubiquitin-protein ligase RNF31-like [Source:NCBI gene;Acc:103040600])

HSP 1 Score: 120.553 bits (301), Expect = 1.205e-28
Identity = 114/385 (29.61%), Postives = 173/385 (44.94%), Query Frame = 1

Query:  292 INLKKNE-PRIGYRDGPFLDKQEVYSEVIE-------PYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFA-KKNTSLYFLSFQEIVNS---DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIK--CPKCNELSCKKCKNKW---HENEFCDFTK--QNGNQNIFQD------FSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCK---EQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQD--------FEKPKNSTLTLCDI--EIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            I LKK E   +   +G   +K E++  ++        P DV++A+     +      L   CP+C +     KM  M +C+C FC++C+K +   VI   S    +CP C  P++  A ++  S+ + S  +       D     ++  K   + +    N  WC +  CS+G     H  D+++  CP C + +C  CK+ W   HE   C+  K  Q  N   +Q+       S N IDCPKC+ +F+L KGGCLH  C +C+HEFC  C + F R G        C      HAHHP+ C Y LRD DV  L S +Q         + +   S L    +   ++      S   +PC +       G CT H+KE +  LI
Sbjct:  396 IQLKKFEGSEVLIPEGVRGEKAEMFRSILSLGDCNFNPADVLEAVQACRDLPSALKYLSHDCPICQEQMSFGKMITMTHCSCTFCESCFKAYFSSVIKEKSIVHAVCPMCNQPDVRGAGRREESMEYFSLLDTQIRHYLDPQTHELFQRKLRDQALQEMPNFRWCAH--CSFGL---LHEADRLRMDCPNCGKSTCFNCKSPWASQHEGLSCEKFKEWQQLNSPEYQNSRLELLLSRNKIDCPKCRFRFFLSKGGCLHFKCTQCQHEFCGGCSRPF-RNGSACNFSAECGT-KGLHAHHPRDCLYHLRDWDVARLCSLLQHHGVAHPLIYSQRDGSVLGSQRVVCAVFEHKELGSPREEPCGRVALPEYNGYCTLHYKECLVELI 773

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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf144ab (probable E3 ubiquitin-protein ligase RNF144A-B [Source:NCBI gene;Acc:103030723])

HSP 1 Score: 62.003 bits (149), Expect = 3.045e-10
Identity = 48/187 (25.67%), Postives = 73/187 (39.04%), Query Frame = 1

Query:  451 CPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCP--SCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISN---HVNDKIKCPKCNELSCKKCKNKWHENEFCD--------FTKQNGNQNIFQDFSHNLIDCPKCKAKFYLDKG 972
            C LCL  FPL KM ++  C C FC  C K +V  +I       + CP  +CP          L  +  + +V +D   R  Y   +    +  D    WC +  C     +      V   ++CP C+   C  C+  WH  + C            +NG+    ++    +  CPKCK     D+G
Sbjct:   42 CKLCLGEFPLEKMTSISQCQCVFCSLCLKQYVELLIREGLETGISCPDSACPNQG------QLQEIEIEAMVTADVMQR--YKRLQFEREVLLDPCRTWCPSSSCQAVCQLKEAEVRVPQLVQCPLCSLRFCSSCRGDWHIGQACRSSLPIITFLPGENGSICKSEEDEAPIKRCPKCKVYIERDEG 220

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BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Match: rnf19b (ring finger protein 19B [Source:NCBI gene;Acc:103021791])

HSP 1 Score: 60.077 bits (144), Expect = 3.562e-9
Identity = 50/210 (23.81%), Postives = 81/210 (38.57%), Query Frame = 1

Query:  430 KDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTKQNGNQNIFQDFSHN------------LIDCPKCKAKFY-LDKGGCLHLN 990
            +D+L+  CPLCL   P  ++  +  C+ + C  C + ++R  I  S   +L CP C E   A +  +L           D  L   Y E  +   +  D +  WC    C +    S        C  C  L C++          CK  WH N+ CD  +Q    ++    +H+            +  CP+C A    ++ G C H+ 
Sbjct:  108 QDLLE--CPLCLVRQPRDQLAELQGCSHRSCLCCLRQYLRIEITESRV-QLSCPECAE-RLAPRQVALIL--------DDPALLEKYEEFLLRRCLASDPDCRWCPAPDCGFAVIASG-------CASCPRLVCRREGCGAEFCYHCKQAWHPNQTCDSARQQRALSLRTHSTHSPSYTAEQGPTDDIKPCPRCGAYIIKMNDGSCNHMT 298

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BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006434.1 (pep scaffold:Pmarinus_7.0:GL492086:439:5313:1 gene:ENSPMAG00000005812.1 transcript:ENSPMAT00000006434.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 62.3882 bits (150), Expect = 2.159e-11
Identity = 54/166 (32.53%), Postives = 76/166 (45.78%), Query Frame = 1

Query:  730 NTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFC----------DFTKQNGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXX-----XXXXXXXQFVREGCKEQNCPMP---NSFHAHHPKYCAYFLRDLDVNELESQIQD 1164
            N  WC +  C  G  I + +  ++ C  CN+ +C KCK  W   HE   C          D   Q      F     N I CPKCK ++ L KGGC+H  C +CKHE     +    ++   R+   E  C M       HAHHP+ C ++LRD D+  L++ + D
Sbjct:   28 NFRWCAH--CPNG-SIHDALRLRMDCTYCNKSTCSKCKKPWEVQHEGLTCEAFHTWKLDNDPEMQAAGLAAF--LKENGIACPKCKFRYALAKGGCMHFTCGQCKHEFCSGCYNPAAERSVHRDVNPESECGMGCTHMGLHAHHPRDCLHYLRDWDIARLQALLTD 188

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BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: rnf19a (ring finger protein 19A, RBR E3 ubiquitin protein ligase [Source:ZFIN;Acc:ZDB-GENE-030131-9414])

HSP 1 Score: 60.077 bits (144), Expect = 5.661e-10
Identity = 51/206 (24.76%), Postives = 82/206 (39.81%), Query Frame = 1

Query:  448 KCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKK----------CKNKWHENEFCDFTK------------QNGNQNIFQDFSH--NLIDCPKCKAKFY-LDKGGCLHLN 990
            +CPLCL          +L C  + C  C + ++R  I  S  + + CP C E         L     Q I+ +D TL   Y E  +  F+  D +  WC    C +    +        C  C +L+C++          CK  WH N+ CD  +            Q+ + +  QD +H  ++  CP+C A    ++ G C H+ 
Sbjct:  109 ECPLCLVRRSAEHFPELLSCPHRSCLDCLRQYLRIEISESRVN-ICCPECAER--------LNPHDIQRIL-ADATLMGKYEEFMLRRFLVADPDCRWCPAPDCGFAVIATG-------CASCPKLTCEREGCGTEFCYHCKAMWHPNQTCDAARQQRSATLRLRSIQSASASYSQDGAHADDIKPCPRCAAYIMKMNDGSCNHMT 297

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BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007741.1 (pep scaffold:Pmarinus_7.0:GL477427:676:25209:1 gene:ENSPMAG00000006996.1 transcript:ENSPMAT00000007741.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 48.1358 bits (113), Expect = 4.194e-6
Identity = 43/195 (22.05%), Postives = 78/195 (40.00%), Query Frame = 1

Query:  442 QRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDR-CSYGFDISNHVNDKIKCPKCNELSCKKCKN-KWHENEFCD----FTKQNG-----NQNIFQDFSHNLID--CPKCKAKFYLDKGGCLHL 987
            Q  CP+CL      ++   LYC  + CK+C++ +++  I  +   K    +CP M+   + T  +  +  E    D     +Y    +  +++  +N  WC N + C               C KC+  +C  C   + H    C+    +  + G     + +        LI   CP C A+   ++ GCLH+
Sbjct: 1390 QPTCPICLGVTGEVELLAPLYCTHRCCKSCWRAYLKTSIDQNMLAKC---TCPIMDCPAQPTGAFIRTMME---DDSDRLELYKRALLRGYVESCSNLAWCANPQGCDRVLCKDGTGGHAATCAKCHWSTCFSCSFLEAHCPASCNQIAWWVDEGGYYEGMSSDALSKHLAKLISKPCPSCHAQIEKNE-GCLHM 1577

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BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Match: EDO46475 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RQ03])

HSP 1 Score: 118.242 bits (295), Expect = 2.513e-28
Identity = 94/338 (27.81%), Postives = 159/338 (47.04%), Query Frame = 1

Query:  385 DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPE-MNFAKKNTSLYFLSFQEIVNS---DETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HEN----EFCDFTKQNGNQ----NIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMP-----NSFHAHHPKYCAYFLRDLDVNELESQIQD----FEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            D I A  D   +   K  LQR+C +C+D  P ++M  ML C C+FC  C   +V+++I   +   L+CP+C E  N      +  + +  +I+     D    +++  K     + ++ N  WC++  CS GF        K+ CP C++ +C +CK +W   HE     +F  + + N  +     +      N I+CP CK ++ L KGGC+H  C +C HE+C  C   F R G    +CP+         HAHHP+ C ++LRD D  EL+  + +    F+  + +        +  ++   ++  + C + T     GLC  H+ EY+   +
Sbjct:  624 DSIIAAQDNGDLERSKKFLQRECIVCMDLKPENRMITMLNCQCRFCSDCVSQYVKQIIQEQNIMHLVCPACSEPKNLEDDTVATNYFNLLDILIRPLVDNPTHDLFQRKLRDRTLMKEPNFRWCSH--CSSGFINERPGILKMPCPHCHKYTCFQCKKQWEDQHEGISCEQFAAWKEANDPEAQATGLAAHLKQNGIECPNCKFRYDLAKGGCMHFKCGQCSHEYCSGCYGPF-RHGA---HCPVSPHCAMRGLHAHHPRDCLFYLRDRDPEELQQLLAENNVAFDTEEGAAAAPGHCRVMEQAEAGTEDKE-CGRPTPDGYAGLCRMHYIEYLVERV 954

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BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000016758.2 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101174057])

HSP 1 Score: 125.176 bits (313), Expect = 3.820e-30
Identity = 98/349 (28.08%), Postives = 163/349 (46.70%), Query Frame = 1

Query:  358 VYSEVIEP------YDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVY--YEKRMSEF-IDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCDFTKQ--------NGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ------DFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            V S ++EP       DV+ A+ +    + I+ +L  +CP+CL  FP SKM ++  C C  C  C+       I +     ++CP C E +         + S  +I   D  L +VY  + K+++E  + +D   +WC +  C+ GF I++    K+ C  C++  C KCK  W   H++  C+  +Q           Q +      N I C +C  ++ L KGGC+H  C +C+++FC  C   + +  CK   C  P   HAHHP+ C ++LRD D   L++ +Q      + +    +    C + +  K     +   PC   T     GLC  H++EY+ +LI
Sbjct:  710 VLSLLLEPDVSYSLEDVVHAVKESHDKDFIRRLLNNECPICLSIFPRSKMQSLTSCQCSVCHECFSQHFTVAIRDKHIRDMVCPVCGEPDINDPQQLDSYFSTLDIQLRDCLLHDVYELFHKKLTEHTLMKDPKFLWCCH--CTSGF-INDGDQLKVTCLSCHKSFCAKCKKAWEPQHQDVSCEQFQQWKRDNDPEYQKQGLAGYLRDNGITCLQCGFQYALTKGGCMHFTCSQCRYQFCSGCNNPYHKTACKAPQCSYPG-LHAHHPRDCLFYLRDWDAARLQALLQRNRVGYNTDPSSGAQTDACGV-MEQKDEGGQQVDSPCGVQTQPGQAGLCDKHYREYLVSLI 1053

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BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028853.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 122.094 bits (305), Expect = 4.613e-29
Identity = 98/339 (28.91%), Postives = 162/339 (47.79%), Query Frame = 1

Query:  379 PY---DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKK-NTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ----DF--EKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            PY   DV+QA+ +      I+ +L ++CP+CL  FP SKM ++  C C  C  C++      + +     ++CP C  P++N  +  N+    L  Q     +  +  ++++K   + + +D   +WC +  CSYGF I +    K+ C +C    C +CK  W   HE   C+    + ++N      Q +      N I CP C+ ++ L KGGC+H  C +C+++FC  C   F    C    C + +  HAHHP+ C ++LRD +   L++ +Q    DF  E P  +   LC + I  K     +    C   T      LC  H++EY+ +LI
Sbjct:  688 PYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVCWEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSV-SGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGV-IEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLI 1020

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000005329.2 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 121.709 bits (304), Expect = 5.021e-29
Identity = 98/339 (28.91%), Postives = 162/339 (47.79%), Query Frame = 1

Query:  379 PY---DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKK-NTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ----DF--EKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            PY   DV+QA+ +      I+ +L ++CP+CL  FP SKM ++  C C  C  C++      + +     ++CP C  P++N  +  N+    L  Q     +  +  ++++K   + + +D   +WC +  CSYGF I +    K+ C +C    C +CK  W   HE   C+    + ++N      Q +      N I CP C+ ++ L KGGC+H  C +C+++FC  C   F    C    C + +  HAHHP+ C ++LRD +   L++ +Q    DF  E P  +   LC + I  K     +    C   T      LC  H++EY+ +LI
Sbjct:  688 PYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVCWEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSV-SGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGV-IEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLI 1020

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044452.1 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101155382])

HSP 1 Score: 121.709 bits (304), Expect = 5.021e-29
Identity = 98/339 (28.91%), Postives = 162/339 (47.79%), Query Frame = 1

Query:  379 PY---DVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNFAKK-NTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCD----FTKQN----GNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQ----DF--EKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            PY   DV+QA+ +      I+ +L ++CP+CL  FP SKM ++  C C  C  C++      + +     ++CP C  P++N  +  N+    L  Q     +  +  ++++K   + + +D   +WC +  CSYGF I +    K+ C +C    C +CK  W   HE   C+    + ++N      Q +      N I CP C+ ++ L KGGC+H  C +C+++FC  C   F    C    C + +  HAHHP+ C ++LRD +   L++ +Q    DF  E P  +   LC + I  K     +    C   T      LC  H++EY+ +LI
Sbjct:  688 PYSLEDVVQAVRESHDREFIRRVLAKECPICLSVFPHSKMQSLTSCQCSVCCDCFQQHFTIAVRDKHIRDMVCPVCWEPDINDPEHLNSYFSTLDIQLRECLEPEVYELFHKKLTEQALIKDPKFLWCCH--CSYGF-IYDGDQLKVTCFQCRNSFCAQCKKPWEPQHEGLSCEQYQTWKRENDPEYQRQGLAGYLRDNGITCPNCRFQYALSKGGCMHFCCSQCRYQFCSGCNNPF-HTTCAVDGCSV-SGLHAHHPRDCLFYLRDWEPARLQALLQNNGVDFNTEPPPGTQTGLCGV-IEQKDEGGQQSDAACGAQTQSGHAALCEKHYREYLVSLI 1020

[Close]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Match: si:dkey-181m9.8 (E3 ubiquitin-protein ligase RNF31 [Source:NCBI gene;Acc:101162956])

HSP 1 Score: 102.064 bits (253), Expect = 1.452e-22
Identity = 97/362 (26.80%), Postives = 153/362 (42.27%), Query Frame = 1

Query:  340 FLDKQEVYSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSC--PEMNF--AKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFI-----DRDANTM----WCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKW---HENEFCDFTKQNGNQNIFQDFS----HNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVR-EGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFE------KPKNST------LTLCDIEIYNXXXXXXXXXXPCYKDT-----GLCTDHFKEYIAALI 1311
            FL    +  +   P D ++A+      +     L   CP+C +    SK+  M +C+C  C+ C+  +    I   S D+L+CP C  PE+      ++ + YF       N  +T    Y  + + E       DR    M    WC +  CS+G  +      ++ CP C + +C +C++ W   H+   C+  K    QN           N I+CP C++ F L +GGCLH  C +C+H+FC  C + F     C           HAHHP+ C + LRD  V+ L   +Q +       KP + +        +C   +       SK  +PC + T     G C  H+KE +  LI
Sbjct:  366 FLALMTLQGQSFSPADALEAVQLNKDFSSALKFLTHTCPICHEQVSFSKIVTMTHCSCFLCQVCFTAFFSVAIKERSVDQLVCPQCGKPEVRAQGGLEDATEYF-------NLLDTQIRHYLPRDIHELFQRKLRDRTLREMPDFCWCAH--CSFGI-LHEAERLRMDCPSCKKSTCSRCRSPWAPQHQRLSCEQFKAWQEQNQLDHHGSTPISNSIECPGCRSVFSLARGGCLHFTCTQCQHQFCGGCARTFTAGSACGFSAECGTKGLHAHHPRDCLFHLRDWSVSRLLLLLQHYRISPAWIKPASGSSSDGTQTAVCS--VLELRDDGSKREEPCGRPTPQGFQGYCQLHYKERLVELI 715

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000036117.1 (SMESG000036117.1)

HSP 1 Score: 719.153 bits (1855), Expect = 0.000e+0
Identity = 375/402 (93.28%), Postives = 385/402 (95.77%), Query Frame = 1

Query:   73 MGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHENEFCDFTKQNGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCT 1278
            MGNTSNKVDRIKATKI  FFS MNANKTKKDVD SDK KRQKLSKSL NIAEINDTDQYD+IYSNKRTERTNDIN KKNEPRIGYRDG FLD QEVYSE IEPYDVIQALNDLTKIND+KDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWV+EVIMNSSCDKLLC SCPEMNFAKKNTSL+FLSFQEIVNSDETLRNVYY+KRMSEFIDRDANTMWCTNDRC YGFDISNHVNDKIK PKCNELSCKKCKNKWHE+EF DFTKQNGNQNIFQDFSH LIDCPKCKAKFYL KGGCLHLNCIKCKHEFC+CC KQFVREGCKEQNCPMP++FHAHHPKYCAYFLRDLDVNELESQI+DFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCT
Sbjct:    1 MGNTSNKVDRIKATKIRAFFSIMNANKTKKDVDKSDKTKRQKLSKSLPNIAEINDTDQYDEIYSNKRTERTNDINFKKNEPRIGYRDGSFLDNQEVYSEAIEPYDVIQALNDLTKINDLKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVKEVIMNSSCDKLLCSSCPEMNFAKKNTSLHFLSFQEIVNSDETLRNVYYKKRMSEFIDRDANTMWCTNDRCLYGFDISNHVNDKIKSPKCNELSCKKCKNKWHESEFFDFTKQNGNQNIFQDFSHKLIDCPKCKAKFYLTKGGCLHLNCIKCKHEFCDCCNKQFVREGCKEQNCPMPDNFHAHHPKYCAYFLRDLDVNELESQIEDFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCT 402

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000036117.1 (SMESG000036117.1)

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 356/380 (93.68%), Postives = 366/380 (96.32%), Query Frame = 1

Query:  139 MNANKTKKDVDISDKAKRQKLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCKKCKNKWHENEFCDFTKQNGNQNIFQDFSHNLIDCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCT 1278
            MNANKTKKDVD SDK KRQKLSKSL NIAEINDTDQYD+IYSNKRTERTNDIN KKNEPRIGYRDG FLD QEVYSE IEPYDVIQALNDLTKIND+KDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWV+EVIMNSSCDKLLC SCPEMNFAKKNTSL+FLSFQEIVNSDETLRNVYY+KRMSEFIDRDANTMWCTNDRC YGFDISNHVNDKIK PKCNELSCKKCKNKWHE+EF DFTKQNGNQNIFQDFSH LIDCPKCKAKFYL KGGCLHLNCIKCKHEFC+CC KQFVREGCKEQNCPMP++FHAHHPKYCAYFLRDLDVNELESQI+DFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCT
Sbjct:    1 MNANKTKKDVDKSDKTKRQKLSKSLPNIAEINDTDQYDEIYSNKRTERTNDINFKKNEPRIGYRDGSFLDNQEVYSEAIEPYDVIQALNDLTKINDLKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVKEVIMNSSCDKLLCSSCPEMNFAKKNTSLHFLSFQEIVNSDETLRNVYYKKRMSEFIDRDANTMWCTNDRCLYGFDISNHVNDKIKSPKCNELSCKKCKNKWHESEFFDFTKQNGNQNIFQDFSHKLIDCPKCKAKFYLTKGGCLHLNCIKCKHEFCDCCNKQFVREGCKEQNCPMPDNFHAHHPKYCAYFLRDLDVNELESQIEDFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCT 380

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000000587.1 (SMESG000000587.1)

HSP 1 Score: 276.944 bits (707), Expect = 8.722e-87
Identity = 134/158 (84.81%), Postives = 139/158 (87.97%), Query Frame = 1

Query:  361 YSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCK 834
            Y  VIEPYDVIQALNDLTKINDIK ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDR   G+       +  K P+  +L+ K
Sbjct:  357 YENVIEPYDVIQALNDLTKINDIKYILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDR---GY-------ESYKVPEVKQLTTK 504

HSP 2 Score: 150.214 bits (378), Expect = 1.988e-39
Identity = 74/80 (92.50%), Postives = 77/80 (96.25%), Query Frame = 1

Query:  139 MNANKTKKDVDISDKAKRQKLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIE 378
            MNANKTKKDVDISDKAKRQKLSKSLSNIAEIND DQYD+IYSNKRTERTNDINLKKNEPRIGYRDGPFLD QE+YSEV +
Sbjct:    1 MNANKTKKDVDISDKAKRQKLSKSLSNIAEINDIDQYDEIYSNKRTERTNDINLKKNEPRIGYRDGPFLDNQEIYSEVTD 80

HSP 3 Score: 89.7373 bits (221), Expect = 7.434e-19
Identity = 55/109 (50.46%), Postives = 64/109 (58.72%), Query Frame = 1

Query:  103 IKATKIMEFFSKMNANKTKKDVDISDKAKRQ-----------------KLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIE 378
            I   KI  FFSK+  NKTK DVD SD  K Q                 +LSKSL  IAEINDTDQYD+IYSNK  E+ N + +K NE R  YRD PFL   E+Y+EV +
Sbjct:  140 INLDKIRTFFSKIILNKTKTDVDESDVGKTQIEAKSKKQKFKKIFLQRELSKSLPAIAEINDTDQYDEIYSNKMKEKANVLIIKMNETRNFYRDRPFLGNHEIYAEVTD 248

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000000587.1 (SMESG000000587.1)

HSP 1 Score: 277.33 bits (708), Expect = 9.080e-87
Identity = 134/158 (84.81%), Postives = 139/158 (87.97%), Query Frame = 1

Query:  361 YSEVIEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNELSCK 834
            Y  VIEPYDVIQALNDLTKINDIK ILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDR   G+       +  K P+  +L+ K
Sbjct:  379 YENVIEPYDVIQALNDLTKINDIKYILQRKCPLCLDCFPLSKMHNMLYCACQFCKTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDETLRNVYYEKRMSEFIDRDANTMWCTNDR---GY-------ESYKVPEVKQLTTK 526

HSP 2 Score: 192.971 bits (489), Expect = 7.007e-55
Identity = 96/102 (94.12%), Postives = 99/102 (97.06%), Query Frame = 1

Query:   73 MGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIE 378
            MGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNIAEIND DQYD+IYSNKRTERTNDINLKKNEPRIGYRDGPFLD QE+YSEV +
Sbjct:    1 MGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNIAEINDIDQYDEIYSNKRTERTNDINLKKNEPRIGYRDGPFLDNQEIYSEVTD 102

HSP 3 Score: 89.7373 bits (221), Expect = 8.024e-19
Identity = 58/121 (47.93%), Postives = 69/121 (57.02%), Query Frame = 1

Query:  103 IKATKIMEFFSKMNANKTKKDVDISDKAKRQ-----------------KLSKSLSNIAEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEVIEPYDVIQALNDLT 414
            I   KI  FFSK+  NKTK DVD SD  K Q                 +LSKSL  IAEINDTDQYD+IYSNK  E+ N + +K NE R  YRD PFL   E+Y+EV + Y    + N+ T
Sbjct:  162 INLDKIRTFFSKIILNKTKTDVDESDVGKTQIEAKSKKQKFKKIFLQRELSKSLPAIAEINDTDQYDEIYSNKMKEKANVLIIKMNETRNFYRDRPFLGNHEIYAEVTD-YKATNSGNEST 281

[Close]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Match: SMESG000000776.1 (SMESG000000776.1)

HSP 1 Score: 229.565 bits (584), Expect = 1.131e-73
Identity = 139/142 (97.89%), Postives = 141/142 (99.30%), Query Frame = 1

Query:  931 DCPKCKAKFYLDKGGCLHLNXXXXXXXXXXXXXXQFVREGCKEQNCPMPNSFHAHHPKYCAYFLRDLDVNELESQIQDFEKPKNSTLTLCDIEIYNXXXXXXXXXXPCYKDTGLCTDHFKEYIAALIFKKNREVYYEKMVSN 1356
            DCPKCKAKFYLDKGGCLHLNCIKCKHEFCECCKKQFVREGCKEQNC MPNSFHAHHPKYCAYFLRDLDVNELESQI+DFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCTDHFKEYIAAL+FKKNREVYYEKMVSN
Sbjct:   18 DCPKCKAKFYLDKGGCLHLNCIKCKHEFCECCKKQFVREGCKEQNCSMPNSFHAHHPKYCAYFLRDLDVNELESQIEDFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGLCTDHFKEYIAALVFKKNREVYYEKMVSN 159

The following BLAST results are available for this feature:

BLAST of RING-type domain-containing protein vs. Ensembl Human
BLAST of RING-type domain-containing protein vs. Ensembl Celegans
BLAST of RING-type domain-containing protein vs. Ensembl Fly
BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
BLAST of RING-type domain-containing protein vs. Ensembl Mouse
BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
BLAST of RING-type domain-containing protein vs. TrEMBL
BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
BLAST of RING-type domain-containing protein vs. Ensembl Yeast
BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
BLAST of RING-type domain-containing protein vs. Ensembl Medaka
BLAST of RING-type domain-containing protein vs. Planmine SMEST

BLAST of RING-type domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
AL136295.10	1.002e-29	27.81	novel transcript	[more]
RNF31	1.002e-29	27.81	ring finger protein 31 [Source:HGNC Symbol;Acc:HGN...	[more]
RNF31	1.002e-29	27.81	ring finger protein 31 [Source:HGNC Symbol;Acc:HGN...	[more]
AL136295.5	1.002e-29	27.81	novel transcript	[more]
RNF31	1.398e-29	27.81	ring finger protein 31 [Source:HGNC Symbol;Acc:HGN...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
C17H11.6	3.236e-9	23.27	RBR-type E3 ubiquitin transferase [Source:UniProt...	[more]
C17H11.6	3.236e-9	23.27	RBR-type E3 ubiquitin transferase [Source:UniProt...	[more]
C17H11.6	3.682e-9	23.27	RBR-type E3 ubiquitin transferase [Source:UniProt...	[more]
C17H11.6	3.682e-9	23.27	RBR-type E3 ubiquitin transferase [Source:UniProt...	[more]
C17H11.6	3.818e-9	23.27	RBR-type E3 ubiquitin transferase [Source:UniProt...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LUBEL	5.959e-26	28.19	gene:FBgn0031857 transcript:FBtr0331216	[more]
LUBEL	6.056e-26	28.19	gene:FBgn0031857 transcript:FBtr0331218	[more]
LUBEL	6.164e-26	28.19	gene:FBgn0031857 transcript:FBtr0331220	[more]
LUBEL	6.922e-26	28.19	gene:FBgn0031857 transcript:FBtr0331221	[more]
ari-1	1.381e-6	19.72	gene:FBgn0017418 transcript:FBtr0089508	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-181m9.8	1.000e-26	27.67	si:dkey-181m9.8 [Source:ZFIN;Acc:ZDB-GENE-070912-3...	[more]
FO834800.1	3.607e-25	28.57	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]
FO834800.2	4.406e-16	27.20	E3 ubiquitin-protein ligase RNF31-like [Source:NCB...	[more]
rnf144ab	7.944e-9	24.37	ring finger protein 144ab [Source:NCBI gene;Acc:43...	[more]
si:ch211-278j3.3	1.257e-8	23.79	si:ch211-278j3.3 [Source:ZFIN;Acc:ZDB-GENE-041014-...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
rnf31	2.122e-31	29.64	ring finger protein 31 [Source:NCBI gene;Acc:10003...	[more]
rnf31	5.715e-31	28.88	ring finger protein 31 [Source:NCBI gene;Acc:10003...	[more]
rnf31	7.553e-31	28.88	ring finger protein 31 [Source:NCBI gene;Acc:10003...	[more]
rnf31	8.537e-31	28.88	ring finger protein 31 [Source:NCBI gene;Acc:10003...	[more]
rnf31	9.466e-28	28.99	ring finger protein 31 [Source:NCBI gene;Acc:10003...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Rnf31	1.473e-29	27.22	ring finger protein 31 [Source:MGI Symbol;Acc:MGI:...	[more]
Rnf31	1.596e-29	27.22	ring finger protein 31 [Source:MGI Symbol;Acc:MGI:...	[more]
Rnf19b	1.154e-9	23.53	ring finger protein 19B [Source:MGI Symbol;Acc:MGI...	[more]
Rnf19b	1.327e-9	23.41	ring finger protein 19B [Source:MGI Symbol;Acc:MGI...	[more]
Rnf31	2.232e-9	41.25	ring finger protein 31 [Source:MGI Symbol;Acc:MGI:...	[more]

BLAST of RING-type domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q96EP0\|RNF31_HUMAN	4.812e-29	27.81	E3 ubiquitin-protein ligase RNF31 OS=Homo sapiens ...	[more]
sp\|Q924T7\|RNF31_MOUSE	1.117e-28	27.22	E3 ubiquitin-protein ligase RNF31 OS=Mus musculus ...	[more]
sp\|Q8IPJ3\|LUBEL_DROME	5.973e-25	28.19	E3 ubiquitin-protein ligase lubel OS=Drosophila me...	[more]
sp\|A2A7Q9\|RN19B_MOUSE	9.285e-9	23.41	E3 ubiquitin-protein ligase RNF19B OS=Mus musculus...	[more]
sp\|Q6ZMZ0\|RN19B_HUMAN	9.868e-9	23.30	E3 ubiquitin-protein ligase RNF19B OS=Homo sapiens...	[more]

BLAST of RING-type domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2T7NIC0	1.510e-30	29.82	Uncharacterized protein OS=Pomacea canaliculata OX...	[more]
H2ZW95	8.232e-30	29.88	Uncharacterized protein OS=Latimeria chalumnae OX=...	[more]
M3ZQS2	1.535e-29	29.73	Ring finger protein 31 OS=Xiphophorus maculatus OX...	[more]
V4A3V4	2.195e-29	29.74	RING-type domain-containing protein (Fragment) OS=...	[more]
V9KFD6	3.838e-29	30.27	RING finger protein 31 OS=Callorhinchus milii OX=7...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000018785.2	7.119e-31	26.21	E3 ubiquitin-protein ligase RNF31-like [Source:NCB...	[more]
ENSAMXT00000014446.2	5.434e-29	27.78	ring finger protein 31 [Source:NCBI gene;Acc:10303...	[more]
si:dkey-181m9.8	1.205e-28	29.61	E3 ubiquitin-protein ligase RNF31-like [Source:NCB...	[more]
rnf144ab	3.045e-10	25.67	probable E3 ubiquitin-protein ligase RNF144A-B [So...	[more]
rnf19b	3.562e-9	23.81	ring finger protein 19B [Source:NCBI gene;Acc:1030...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSPMAT00000006434.1	2.159e-11	32.53	pep scaffold:Pmarinus_7.0:GL492086:439:5313:1 gene...	[more]
rnf19a	5.661e-10	24.76	ring finger protein 19A, RBR E3 ubiquitin protein ...	[more]
ENSPMAT00000007741.1	4.194e-6	22.05	pep scaffold:Pmarinus_7.0:GL477427:676:25209:1 gen...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of RING-type domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO46475	2.513e-28	27.81	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of RING-type domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000016758.2	3.820e-30	28.08	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]
ENSORLT00000028853.1	4.613e-29	28.91	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]
ENSORLT00000005329.2	5.021e-29	28.91	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]
ENSORLT00000044452.1	5.021e-29	28.91	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]
si:dkey-181m9.8	1.452e-22	26.80	E3 ubiquitin-protein ligase RNF31 [Source:NCBI gen...	[more]

BLAST of RING-type domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000036117.1	0.000e+0	93.28	SMESG000036117.1	[more]
SMESG000036117.1	0.000e+0	93.68	SMESG000036117.1	[more]
SMESG000000587.1	8.722e-87	84.81	SMESG000000587.1	[more]
SMESG000000587.1	9.080e-87	84.81	SMESG000000587.1	[more]
SMESG000000776.1	1.131e-73	97.89	SMESG000000776.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024800 ID=SMED30024800|Name=RING-type domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1409bp
ATCTATATAAATCTTATATGAGTGCCTTGTAAGTAAAATAATTTACAAAA
GTTAGTGAAGCAAATTTCAAGAATGGGTAATACCAGTAATAAAGTCGATC
GAATAAAGGCTACAAAAATTATGGAATTTTTTTCTAAAATGAATGCTAAT
AAAACGAAAAAAGATGTTGATATCAGTGATAAGGCTAAGAGACAAAAACT
TAGTAAATCTCTATCAAATATAGCAGAAATAAATGACACAGATCAATATG
ATGATATCTATTCGAATAAAAGGACAGAAAGAACAAATGATATTAATTTA
AAAAAGAATGAACCAAGAATTGGTTATCGGGACGGGCCATTTTTGGATAA
ACAAGAAGTTTACTCCGAGGTCATTGAACCTTATGATGTTATTCAAGCCT
TAAATGATTTAACTAAAATAAACGACATAAAAGATATTTTGCAAAGAAAG
TGTCCATTATGTCTTGACTGCTTTCCGTTGTCAAAGATGCATAATATGCT
TTATTGTGCTTGTCAGTTTTGCAAAACTTGTTACAAAGACTGGGTTAGGG
AGGTAATAATGAACAGCAGTTGCGATAAGTTGTTGTGTCCCTCTTGTCCG
GAAATGAATTTTGCAAAAAAAAATACGAGTTTGTATTTCCTTTCTTTCCA
AGAAATAGTTAATTCTGATGAAACTCTGAGAAATGTTTACTATGAGAAAC
GGATGTCTGAATTTATTGATAGAGATGCAAATACTATGTGGTGCACTAAT
GATAGATGCTCATATGGATTTGATATATCTAATCATGTCAATGACAAAAT
TAAATGCCCAAAATGTAATGAATTATCGTGCAAGAAGTGCAAAAATAAAT
GGCATGAAAATGAATTTTGTGATTTTACCAAGCAAAATGGAAATCAAAAT
ATTTTCCAAGACTTCAGTCATAACTTAATTGATTGTCCAAAATGCAAAGC
CAAATTTTATTTAGACAAAGGCGGCTGTTTGCATTTAAATTGTATTAAAT
GCAAACATGAATTCTGTGAATGTTGTAAGAAGCAATTTGTCAGAGAAGGT
TGCAAGGAGCAGAATTGTCCCATGCCCAACAGCTTTCATGCTCACCATCC
GAAATATTGCGCATATTTTCTGAGAGATCTAGATGTAAATGAATTGGAAT
CACAAATCCAGGATTTTGAAAAACCCAAAAATTCAACCTTGACTCTCTGT
GATATTGAAATTTATAACAAATCATCTAAAGCCAGCAAATGCTCCAAACC
CTGTTACAAGGATACAGGGTTATGCACAGATCATTTTAAAGAATACATAG
CCGCATTGATATTCAAAAAAAATCGAGAGGTCTACTATGAAAAAATGGTT
TCTAATTAATCCCTGTTTTGAATTTTTAACACATTAAATTTTTTTGTCTT
CAAAAAAAA

protein sequence of SMED30024800-orf-1

>SMED30024800-orf-1 ID=SMED30024800-orf-1|Name=SMED30024800-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=429bp
MGNTSNKVDRIKATKIMEFFSKMNANKTKKDVDISDKAKRQKLSKSLSNI
AEINDTDQYDDIYSNKRTERTNDINLKKNEPRIGYRDGPFLDKQEVYSEV
IEPYDVIQALNDLTKINDIKDILQRKCPLCLDCFPLSKMHNMLYCACQFC
KTCYKDWVREVIMNSSCDKLLCPSCPEMNFAKKNTSLYFLSFQEIVNSDE
TLRNVYYEKRMSEFIDRDANTMWCTNDRCSYGFDISNHVNDKIKCPKCNE
LSCKKCKNKWHENEFCDFTKQNGNQNIFQDFSHNLIDCPKCKAKFYLDKG
GCLHLNCIKCKHEFCECCKKQFVREGCKEQNCPMPNSFHAHHPKYCAYFL
RDLDVNELESQIQDFEKPKNSTLTLCDIEIYNKSSKASKCSKPCYKDTGL
CTDHFKEYIAALIFKKNREVYYEKMVSN*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0016740	transferase activity
GO:0008270	zinc ion binding
GO:0005515	protein binding
GO:0004842	ubiquitin-protein transferase activity
GO:0016874	ligase activity
GO:0046872	metal ion binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000054	dorsal region of the epidermis
PLANA:0000099	neuron
PLANA:0002032	epidermal cell
PLANA:0002089	reproductive organ

Vocabulary: **INTERPRO**
Term	Definition
IPR026254	RNF31-like
IPR002867	IBR_dom
IPR013083	Znf_RING/FYVE/PHD
IPR001841	Znf_RING

Vocabulary: **cellular component**
Term	Definition
GO:0005622	intracellular
GO:0071797	LUBAC complex

Vocabulary: **biological process**
Term	Definition
GO:0016567	protein ubiquitination

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002867	IBR domain	SMART	SM00647	ibrneu5	coord: 182..244 e-value: 4.5E-7 score: 39.5
IPR002867	IBR domain	PFAM	PF01485	IBR	coord: 184..244 e-value: 1.5E-9 score: 37.9
IPR013083	Zinc finger, RING/FYVE/PHD-type	GENE3D	G3DSA:3.30.40.10		coord: 101..195 e-value: 1.9E-8 score: 36.2
IPR026254	E3 ubiquitin-protein ligase RNF31-like	PANTHER	PTHR16004	RING FINGER PROTEIN 31-RELATED	coord: 82..347
None	No IPR available	PROSITE	PS51873	TRIAD	coord: 101..323 score: 19.135
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 184..249
None	No IPR available	SUPERFAMILY	SSF57850	RING/U-box	coord: 104..168
IPR001841	Zinc finger, RING-type	PROSITE	PS50089	ZF_RING_2	coord: 105..153 score: 9.598

Main menu

RING-type domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Owlery

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