Ectonucleoside triphosphate diphosphohydrolase 5

Overview
NameEctonucleoside triphosphate diphosphohydrolase 5
Smed IDSMED30024795
Length (bp)1471
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Ectonucleoside triphosphate diphosphohydrolase 5 (SMED30024795) t-SNE clustered cells

Violin plots show distribution of expression levels for Ectonucleoside triphosphate diphosphohydrolase 5 (SMED30024795) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ectonucleoside triphosphate diphosphohydrolase 5 (SMED30024795) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ectonucleoside triphosphate diphosphohydrolase 5 (SMED30024795) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30024795

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30024795h1SMcG0016849 SmedASXL_004561SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30024795h1SMcG0016849 dd_Smed_v4_15646_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024795h1SMcG0016849 dd_Smed_v4_15646_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30024795h1SMcG0016849 dd_Smed_v4_15646_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Match: ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive) [Source:HGNC Symbol;Acc:HGNC:3367])

HSP 1 Score: 137.117 bits (344), Expect = 4.719e-35
Identity = 112/390 (28.72%), Postives = 181/390 (46.41%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFS------VKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  ++  S K  LS F +     +        L   A  +IP    + TP+ ++ TAG+R + +  +K +L  ++ I  KS        V I+    EG LAWV++N+L G+   ++  ETVG LDLGG STQI+F      T   T   +     +F   Y +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG        F  C+ + L++V      RG   + E V   ++Y     ++   +  + D++++       V+D   +A ++C N +      S   FLC+D+SYI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   51 IMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAET---VQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHR-QETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEV-GFEPCYAEVLRVV------RGKLHQPEEVQRGSFYAF---SYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLEN---FTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Match: ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive) [Source:HGNC Symbol;Acc:HGNC:3367])

HSP 1 Score: 135.191 bits (339), Expect = 1.999e-34
Identity = 105/362 (29.01%), Postives = 169/362 (46.69%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFS------VKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGY 1261
            I+ D GS+GTR+H + F++        L  ++  S K  LS F +     +        L   A  +IP    + TP+ ++ TAG+R + +  +K +L  ++ I  KS        V I+    EG LAWV++N+L G+   ++  ETVG LDLGG STQI+F      T   T   +     +F   Y +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++V      RG   + E V   ++Y     ++   +  + D++++       V+D   +A ++C N +      S   FLC+D+SYI ALL +G+G+
Sbjct:   51 IMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAET---VQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHR-QETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEVGFEPCYAEVLRVV------RGKLHQPEEVQRGSFYAF---SYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLEN---FTSGSPFLCMDLSYITALLKDGFGF 393          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Match: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:HGNC Symbol;Acc:HGNC:3368])

HSP 1 Score: 112.849 bits (281), Expect = 3.000e-26
Identity = 99/381 (25.98%), Postives = 174/381 (45.67%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLK--NDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGG-KPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            + I+ D GS+GTR+H F+F +   +     H T K + K  LS +++   D          L   A  +IP    + TP+ ++ TAG+R +    ++K+L  ++ +   S      + V I++   EG  AW+++N+L G  ++   S +VGMLDLGGGSTQI+F      T   +   +   + +F + Y +Y+  Y  +G+   R+  L        K   + V S CL P  K  +     T  + G K   S    C   +   +++Q  +        ++F A S YY +      I  +    L+   V D    A  +C+  + + +      F C+D++Y+  LL   +G+     + ++ +I+ +  SWALG
Sbjct:   85 YGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETFK-ALKPGLSAYAD---DVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTGSLKTPGGS-SVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELV-SPCLSPSFKGEWEHAEVTYRVSGQKAAASLHELCAARVS--EVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLV---VGDFEIAAKYVCRTLETQPQSSP---FSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDNVETSWALG 450          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Match: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:HGNC Symbol;Acc:HGNC:3368])

HSP 1 Score: 112.849 bits (281), Expect = 3.263e-26
Identity = 99/381 (25.98%), Postives = 174/381 (45.67%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLK--NDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGG-KPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            + I+ D GS+GTR+H F+F +   +     H T K + K  LS +++   D          L   A  +IP    + TP+ ++ TAG+R +    ++K+L  ++ +   S      + V I++   EG  AW+++N+L G  ++   S +VGMLDLGGGSTQI+F      T   +   +   + +F + Y +Y+  Y  +G+   R+  L        K   + V S CL P  K  +     T  + G K   S    C   +   +++Q  +        ++F A S YY +      I  +    L+   V D    A  +C+  + + +      F C+D++Y+  LL   +G+     + ++ +I+ +  SWALG
Sbjct:  101 YGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETFK-ALKPGLSAYAD---DVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTGSLKTPGGS-SVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELV-SPCLSPSFKGEWEHAEVTYRVSGQKAAASLHELCAARVS--EVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLV---VGDFEIAAKYVCRTLETQPQSSP---FSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDNVETSWALG 466          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Match: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:HGNC Symbol;Acc:HGNC:3368])

HSP 1 Score: 112.849 bits (281), Expect = 3.482e-26
Identity = 99/381 (25.98%), Postives = 174/381 (45.67%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLK--NDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGG-KPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            + I+ D GS+GTR+H F+F +   +     H T K + K  LS +++   D          L   A  +IP    + TP+ ++ TAG+R +    ++K+L  ++ +   S      + V I++   EG  AW+++N+L G  ++   S +VGMLDLGGGSTQI+F      T   +   +   + +F + Y +Y+  Y  +G+   R+  L        K   + V S CL P  K  +     T  + G K   S    C   +   +++Q  +        ++F A S YY +      I  +    L+   V D    A  +C+  + + +      F C+D++Y+  LL   +G+     + ++ +I+ +  SWALG
Sbjct:  102 YGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETFK-ALKPGLSAYAD---DVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKKVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTGSLKTPGGS-SVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTYKLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELV-SPCLSPSFKGEWEHAEVTYRVSGQKAAASLHELCAARVS--EVLQNRVHRTEEVKHVDFYAFSYYYDLAAGVGLIDAEKGGSLV---VGDFEIAAKYVCRTLETQPQSSP---FSCMDLTYVSLLLQE-FGFPRSKVLKLTRKIDNVETSWALG 467          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Match: uda-1 (Nucleoside-diphosphatase uda-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9XU84])

HSP 1 Score: 104.375 bits (259), Expect = 7.902e-24
Identity = 114/467 (24.41%), Postives = 204/467 (43.68%), Query Frame = 2
Query:  146 VLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKN----DNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFK-PEFVDILSTEKEGRLAWVSLNYLLGKFQSNKIS--------ETVGMLDLGGGSTQISFATNNVTLIPHSV----KMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVK-AHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQP--VIPIRGTFDEMEFVAISAYYYIIKSAFN--ITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFL---CLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML**YLYYTSALKVLTLMDNFLLYLDLFCIFKLYFIYSGYDDVM 1471
            VL N++ C           R F IV+D GS+GTRLH ++F+ +     + M   +  +I  +V     S A++  S    +   L   A   +P    E TPI ++ TAG+R +   M+  IL  +   +  S      P+ V+++    EG  +W +LN LL    +++ +         +V   DLGGGSTQ+++  NN  +    V     +  FG    ++T  +   G+   R+  L       ++  +Q + S C+    +   + +  +   I G    S   F +C+      V+   ++ +R    E++   +  + Y    A N  + K NE   +E  ++     A   C+  K E+  D   H++   CLD++YI +LL +GY +E    + ++ +I  + +SW  G A +    +     A+K     +     +D   IF L  +YSG + V+
Sbjct:   33 VLNNQHTC-----------RFFTIVIDAGSTGTRLHLYKFIHDPAIASHGMPFKVEKEIFQEVKPGLSSFAKSPSSAADSL-EPLLQRARKEVPHFMWEKTPITLKATAGLRLLPGDMADDILESVEERIFNSGFFAAFPDAVNVMPGSDEGVYSWFTLNILLETLFTDEPTVGHKPAAHRSVAAFDLGGGSTQLTYWPNNEAVFSEHVGYERDIDFFGHHIRLFTHSFLGNGLIAARLNILQLETDNEIESTHQLITS-CMPEGYQLTEWEYALKFWNING---SSSHSFESCYGTTKNFVESSEIMHLR----ELKGSPVYLFSYFFDRALNSGLVKGNEGGKIE--LRQFKEAAEIACRREKTEI--DDGSHWMPWQCLDLTYIYSLLRDGYQFEDNQPLVLAKKIKGMEVSWGQGLAFATANEFQLTEGAIKTALSSEPNSTVVD--QIFDL--VYSGTNQVL 471          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Match: mig-23 (Nucleoside-diphosphatase mig-23 [Source:UniProtKB/Swiss-Prot;Acc:Q21815])

HSP 1 Score: 80.1073 bits (196), Expect = 8.548e-16
Identity = 99/437 (22.65%), Postives = 176/437 (40.27%), Query Frame = 2
Query:  203 RKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI-SSKVALSKFSNARTDWSLMRIM----FNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLK-SKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQ------------SNKISETVGMLDLGGGSTQI--------SFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTV-RSEC----LHPKVKAHFHFGNRTLVIGGKPIKSC----RRFCN-------CFLKGLK-----MVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFL-----------CLDMSYIVALLHNGYGYE-WFDXXXXXXXXXXXXLSWALGYAI 1336
            R + ++ D GS+GTRL  + ++   ++  + +   I  +K  + K S   + +             L   A  +IPE+    TP+++  TAG+R I     + +L ++R+ L K + +    E + I+  + EG  +W+++NY LGKF             ++   +TVGM+D+GG S QI        SF++ NV  I    +      +Y ++   +   G+NE  IR         LK QN TV + +C    LH  V      G   +  G     +C    ++  N       C  +  K     +  P IP+      +E    S Y+Y       +  Q       +  ++I  +    C      ++ +S +              C   ++I ++LH+G+  +   +K      I    + WALG  I
Sbjct:   42 RSYGVICDAGSTGTRLFVYNWISTSDSELIQIEPVIYDNKPVMKKISPGLSTFGTKPAQAAEYLRPLMELAERHIPEEKRPYTPVFIFATAGMRLIPDEQKEAVLKNLRNKLPKITSMQVLKEHIRIIEGKWEGIYSWIAVNYALGKFNKTATLDFPGTSPAHARQKTVGMIDMGGASAQIAFELPDTDSFSSINVENINLGCREDDSLFKYKLFVTTFLGYGVNE-GIRKYEHMLLSKLKDQNGTVIQDDCMPLNLHKTVT--LENGENFVRRGTGNWNTCSNEVKKLLNPESSSEVCKAEAAKCYFGAVPAPSIPL----SNIEMYGFSEYWYSTHDVLGLGGQ-------YDAENIAKKTQQYCSKRWSTIQAESKKQLYPRADEERLRTQCFKSAWITSVLHDGFSVDKTHNKFQSVSTIAGQEVQWALGAMI 464          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Match: ntp-1 (Nucleoside-triphosphatase ntp-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18411])

HSP 1 Score: 71.633 bits (174), Expect = 4.124e-13
Identity = 51/177 (28.81%), Postives = 90/177 (50.85%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEF------LKNDNNMKLHLTDKISSKV--ALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLK-SKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNN 709
            K+ ++ D GSSGTRL  +        L N + + +H ++ +  KV   LS F +       +      L  FA  +IP + + +T + +  TAG+R + +     I+ ++++ L   + L      + I+    EG  +W+++NY+LG+F     S+ VGM+D+GG S QI+F   N
Sbjct:   82 KYGVICDAGSSGTRLFVYTLKPLSGGLTNIDTL-IHESEPVVKKVTPGLSSFGDKPEQ---VVEYLTPLLRFAEEHIPYEQLGETDLLIFATAGMRLLPEAQKDAIIKNLQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRFDKENDSK-VGMIDMGGASVQIAFEIAN 253          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Match: ntp-1 (Nucleoside-triphosphatase ntp-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18411])

HSP 1 Score: 71.633 bits (174), Expect = 4.246e-13
Identity = 51/177 (28.81%), Postives = 90/177 (50.85%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEF------LKNDNNMKLHLTDKISSKV--ALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLK-SKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNN 709
            K+ ++ D GSSGTRL  +        L N + + +H ++ +  KV   LS F +       +      L  FA  +IP + + +T + +  TAG+R + +     I+ ++++ L   + L      + I+    EG  +W+++NY+LG+F     S+ VGM+D+GG S QI+F   N
Sbjct:   48 KYGVICDAGSSGTRLFVYTLKPLSGGLTNIDTL-IHESEPVVKKVTPGLSSFGDKPEQ---VVEYLTPLLRFAEEHIPYEQLGETDLLIFATAGMRLLPEAQKDAIIKNLQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRFDKENDSK-VGMIDMGGASVQIAFEIAN 219          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Match: ntp-1 (Nucleoside-triphosphatase ntp-1 [Source:UniProtKB/Swiss-Prot;Acc:Q18411])

HSP 1 Score: 71.633 bits (174), Expect = 4.246e-13
Identity = 51/177 (28.81%), Postives = 90/177 (50.85%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEF------LKNDNNMKLHLTDKISSKV--ALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLK-SKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNN 709
            K+ ++ D GSSGTRL  +        L N + + +H ++ +  KV   LS F +       +      L  FA  +IP + + +T + +  TAG+R + +     I+ ++++ L   + L      + I+    EG  +W+++NY+LG+F     S+ VGM+D+GG S QI+F   N
Sbjct:   48 KYGVICDAGSSGTRLFVYTLKPLSGGLTNIDTL-IHESEPVVKKVTPGLSSFGDKPEQ---VVEYLTPLLRFAEEHIPYEQLGETDLLIFATAGMRLLPEAQKDAIIKNLQNGLKSVTALRVSDSNIRIIDGAWEGIYSWIAVNYILGRFDKENDSK-VGMIDMGGASVQIAFEIAN 219          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Match: NTPase (gene:FBgn0024947 transcript:FBtr0077683)

HSP 1 Score: 121.709 bits (304), Expect = 9.581e-30
Identity = 99/392 (25.26%), Postives = 203/392 (51.79%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWS-LMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP----HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAH-FHFGNRTLVIGGKP--IKSCRRFCNCFLKGLKMVQP-VIP-IRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            ++  ++D GS+G+R+  ++F ++  + KL L +++    K  LS F++   + +  ++++ +   +F    IP++    TP+ ++ TAG+R +  + ++ ILN +R +  KS+ +   + V+I+    EG  +W ++N+LLG+      +     LDLGGGSTQ++F+  +   +P    +  ++V   ++ NV+T  + Y+G+  +  R+  A    G K ++  + S C++P +    + +GN    + GK     S  +    F   L++V+  V+P ++     ++  A++A+ Y  + A      +     E +V+    +A ++C  P  E      + F+C D+++I  LL  G+G     KI +  +I+   +SWALG A ++L
Sbjct:   78 QYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAF----IPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSEFSVDMDAVEIMDGTDEGIFSWFTVNFLLGRLSK---TNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFT--HSYLGLGLMAARH--AVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDE------QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVL 452          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Match: NTPase (gene:FBgn0024947 transcript:FBtr0332459)

HSP 1 Score: 121.709 bits (304), Expect = 1.167e-29
Identity = 99/392 (25.26%), Postives = 203/392 (51.79%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWS-LMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP----HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAH-FHFGNRTLVIGGKP--IKSCRRFCNCFLKGLKMVQP-VIP-IRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            ++  ++D GS+G+R+  ++F ++  + KL L +++    K  LS F++   + +  ++++ +   +F    IP++    TP+ ++ TAG+R +  + ++ ILN +R +  KS+ +   + V+I+    EG  +W ++N+LLG+      +     LDLGGGSTQ++F+  +   +P    +  ++V   ++ NV+T  + Y+G+  +  R+  A    G K ++  + S C++P +    + +GN    + GK     S  +    F   L++V+  V+P ++     ++  A++A+ Y  + A      +     E +V+    +A ++C  P  E      + F+C D+++I  LL  G+G     KI +  +I+   +SWALG A ++L
Sbjct:   81 QYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAF----IPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSEFSVDMDAVEIMDGTDEGIFSWFTVNFLLGRLSK---TNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFT--HSYLGLGLMAARH--AVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDE------QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVL 455          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Match: NTPase (gene:FBgn0024947 transcript:FBtr0332460)

HSP 1 Score: 121.709 bits (304), Expect = 1.782e-29
Identity = 99/392 (25.26%), Postives = 203/392 (51.79%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWS-LMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP----HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAH-FHFGNRTLVIGGKP--IKSCRRFCNCFLKGLKMVQP-VIP-IRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            ++  ++D GS+G+R+  ++F ++  + KL L +++    K  LS F++   + +  ++++ +   +F    IP++    TP+ ++ TAG+R +  + ++ ILN +R +  KS+ +   + V+I+    EG  +W ++N+LLG+      +     LDLGGGSTQ++F+  +   +P    +  ++V   ++ NV+T  + Y+G+  +  R+  A    G K ++  + S C++P +    + +GN    + GK     S  +    F   L++V+  V+P ++     ++  A++A+ Y  + A      +     E +V+    +A ++C  P  E      + F+C D+++I  LL  G+G     KI +  +I+   +SWALG A ++L
Sbjct:  141 QYAAIIDAGSTGSRVLAYKFNRSFIDNKLVLYEELFKERKPGLSSFADNPAEGAHSIKLLLDEARAF----IPKEHWSSTPLVLKATAGLRLLPASKAENILNAVRDLFAKSEFSVDMDAVEIMDGTDEGIFSWFTVNFLLGRLSK---TNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFT--HSYLGLGLMAARH--AVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDE------QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVL 515          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Match: NTPase (gene:FBgn0024947 transcript:FBtr0077680)

HSP 1 Score: 79.337 bits (194), Expect = 3.373e-16
Identity = 71/272 (26.10%), Postives = 135/272 (49.63%), Query Frame = 2
Query:  557 VDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP----HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAH-FHFGNRTLVIGGKP--IKSCRRFCNCFLKGLKMVQP-VIP-IRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            V+I+    EG  +W ++N+LLG+      +     LDLGGGSTQ++F+  +   +P    +  ++V   ++ NV+T  + Y+G+  +  R+  A    G K ++  + S C++P +    + +GN    + GK     S  +    F   L++V+  V+P ++     ++  A++A+ Y  + A      +     E +V+    +A ++C  P  E      + F+C D+++I  LL  G+G     KI +  +I+   +SWALG A ++L
Sbjct:    4 VEIMDGTDEGIFSWFTVNFLLGRLSK---TNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFT--HSYLGLGLMAARH--AVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDE------QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVL 262          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Match: NTPase (gene:FBgn0024947 transcript:FBtr0077682)

HSP 1 Score: 79.337 bits (194), Expect = 3.373e-16
Identity = 71/272 (26.10%), Postives = 135/272 (49.63%), Query Frame = 2
Query:  557 VDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP----HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAH-FHFGNRTLVIGGKP--IKSCRRFCNCFLKGLKMVQP-VIP-IRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            V+I+    EG  +W ++N+LLG+      +     LDLGGGSTQ++F+  +   +P    +  ++V   ++ NV+T  + Y+G+  +  R+  A    G K ++  + S C++P +    + +GN    + GK     S  +    F   L++V+  V+P ++     ++  A++A+ Y  + A      +     E +V+    +A ++C  P  E      + F+C D+++I  LL  G+G     KI +  +I+   +SWALG A ++L
Sbjct:    4 VEIMDGTDEGIFSWFTVNFLLGRLSK---TNQAAALDLGGGSTQVTFSPTDPDQVPVYDKYMHEVVTSSKKINVFT--HSYLGLGLMAARH--AVFTHGYKKEDTVLESVCVNPIIANRTWTYGNVQYKVSGKENGKSSAEQPIVDFDACLELVKSKVMPLVKPKPFTLKQHAVAAFSYYFERAIESGLVDPLAGGETTVEAYRKKAQEICAIPNDE------QPFMCFDLTFISTLLREGFGLNDGKKIKLYKKIDGHEISWALGCAYNVL 262          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Match: entpd5b (ectonucleoside triphosphate diphosphohydrolase 5b [Source:ZFIN;Acc:ZDB-GENE-091118-88])

HSP 1 Score: 157.918 bits (398), Expect = 1.346e-42
Identity = 116/388 (29.90%), Postives = 193/388 (49.74%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN-----ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSV-----KMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI--PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAI 1336
            I+ D GS+GTR+H + F++ + +    L +++  S K  LS +++       T   L+R+        A   +P    + TP+  + TAG+R +    +  +L  ++ +  +S     P+ V I++   EG LAWV++N+L G+ + N   +TVG+LDLGGGSTQI+F   +   I  +      +  +F   Y +YT  Y   GI   R+  L A N  GL  + +  RS CL     A F FG  +  + G  I   R +  C+ + +K+V+ +I  P+    D   F A S YY     A  I +Q    +    V+D    A  +C  P +  +L+    FLC+D++YI  LL +G+G++    + ++ ++  +  SWALG AI
Sbjct:   61 IMFDAGSTGTRIHVYTFIQREPDGLPVLDNEMFHSMKPGLSAYADMPEIAGHTVRQLLRV--------AKKTVPPLEWKRTPLVFRATAGLRLLPAAKAHALLEEVQDVFDESPFYVPPDSVRIMNGTSEGILAWVTVNFLTGRLERN-TEKTVGILDLGGGSTQITFLPKSKKTIEAAPPDYISRFQMFNCSYQLYTHSYLGNGIKAARLSALGALNADGL--EKKLFRSSCLSRSHTAEFSFGGVSYHVSGD-ISGVRGYKACYQELVKVVKGIIKQPLE-LRDSSSFYAFSYYYDHAVEAGLIDEQRGGAV---KVRDFRKTARQVCNRPARHTQLN---QFLCMDLTYITCLLKDGFGFKESTVLQLTKKVRNVETSWALGAAI 429          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Match: entpd5b (ectonucleoside triphosphate diphosphohydrolase 5b [Source:ZFIN;Acc:ZDB-GENE-091118-88])

HSP 1 Score: 145.976 bits (367), Expect = 4.307e-38
Identity = 116/418 (27.75%), Postives = 194/418 (46.41%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN-----ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTV------------------------------RSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI--PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAI 1336
            I+ D GS+GTR+H + F++ + +    L +++  S K  LS +++       T   L+R+        A   +P    + TP+  + TAG+R +    +  +L  ++ +  +S     P+ V I++   EG LAWV++N+L G+ + N   +TVG+LDLGGGSTQI+F   +   I  +      +  +F   Y +YT  Y   GI   R+  L A N  G + ++  V                              RS CL     A F FG  +  + G  I   R +  C+ + +K+V+ +I  P+    D   F A S YY     A  I +Q    +    V+D    A  +C  P +  +L+    FLC+D++YI  LL +G+G++    + ++ ++  +  SWALG AI
Sbjct:   61 IMFDAGSTGTRIHVYTFIQREPDGLPVLDNEMFHSMKPGLSAYADMPEIAGHTVRQLLRV--------AKKTVPPLEWKRTPLVFRATAGLRLLPAAKAHALLEEVQDVFDESPFYVPPDSVRIMNGTSEGILAWVTVNFLTGRLERN-TEKTVGILDLGGGSTQITFLPKSKKTIEAAPPDYISRFQMFNCSYQLYTHSYLGNGIKAARLSALGALNADGTRHESVCVFVFICACTFVCVCVHLCVCVCVAGLEKKLFRSSCLSRSHTAEFSFGGVSYHVSGD-ISGVRGYKACYQELVKVVKGIIKQPLE-LRDSSSFYAFSYYYDHAVEAGLIDEQRGGAV---KVRDFRKTARQVCNRPARHTQLN---QFLCMDLTYITCLLKDGFGFKESTVLQLTKKVRNVETSWALGAAI 461          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Match: entpd5a (ectonucleoside triphosphate diphosphohydrolase 5a [Source:ZFIN;Acc:ZDB-GENE-100419-1])

HSP 1 Score: 139.043 bits (349), Expect = 9.276e-36
Identity = 120/409 (29.34%), Postives = 205/409 (50.12%), Query Frame = 2
Query:  143 PVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI---SSKVALSKFSN--ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFAT---NNVTLIP--HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            PV++ E     ++ FS   R  + I+ D GSSGTR+H ++F++ D  ++L + D     + K  LS +++   +   S+++++       A   IP++    TP+ ++ TAG+R + +  +K +LN ++ +   S        V I++   EG LAWV++N+L G   S K   TVG+LDLGGGSTQI+F       V   P  +  K+ +F   Y +YT  Y   G+   R+  L A    GL+   +  RS CL  K    + FG  T  + G P      +  C+ + L++V+ ++     ++G+     F A S YYY       +   +    +E  V+D   +A ++C    K   +  Y   LC+DM+YI  LL +G+G++    + ++ ++N +  SWALG
Sbjct:   53 PVVM-EPVAPRQVNFS---RVFYGIMFDAGSSGTRIHIYKFIQKDP-VELPVLDNEMYHAVKPGLSAYADMPEKGGESIVQLL-----KVAKKTIPKEQWIQTPVVLKATAGLRLLPEEKAKALLNEVKEVFDDSPFFVPNNSVTIMNGINEGVLAWVTVNFLTGHLYS-KTKRTVGILDLGGGSTQITFLPRLKKTVQSAPSDYIAKINMFNSTYELYTHSYLGNGVFASRLATLGALGADGLEW--KVFRSSCLPKKFSEEWSFGGLTYKVSGTP-DGYAGYKLCYQEVLQVVKGIVHQPFEVKGS---SIFYAFS-YYYDRAVESGLIDGSRGGTVE--VRDFKKKAKEVCNKMTKYRPISPY---LCMDMTYITCLLKDGFGFKDSTVLQLAKKVNNVETSWALG 438          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Match: entpd6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:ZFIN;Acc:ZDB-GENE-050417-412])

HSP 1 Score: 129.798 bits (325), Expect = 1.974e-32
Identity = 112/383 (29.24%), Postives = 180/383 (47.00%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNM-KLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFA-TNNVTLIPHSVKMVLFGQQYNV----YTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGG-KPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYA 1333
            ++ I+ D GS+GTR+H F+F    N   KL      + K  LS +++   + S   I+   L + A   +PE     TP+ ++ TAG+R +    +  +L+ +R +  +S   +KP+ V I+    EG  AW+++N+L+G     + + TVGMLDLGGGSTQI+FA  + +T+    +  V   Q +N+    Y+  Y  +G+   R+  L       L    + V S CL P     +        + G KP +    + +C  K  KM+   +        M+F A S YY     A ++   +E       V D I  A  +C N       +S   FLCLD++YI  LL     +    ++ ++ +IN    SWALG A
Sbjct:   60 QYGIMFDAGSTGTRIHIFKFQMEPNEAPKLAHETFRAIKPGLSAYAD-EPEKSKEGIL--ELLNVAKDTVPEVLWSSTPLMLRATAGLRLLPGEKATILLDKVREVFSESLFLYKPDSVSIMDGTDEGMSAWITINFLIGALHGTE-TPTVGMLDLGGGSTQITFALQDEITIQTSPIDYVTSFQMFNISHALYSHSYLGLGLMSARLAVLGGIEGQPLAGPQELV-SPCLAPDYSGQWEHAEVLYTVKGQKPGEPI--YESCLRKVEKMIYKQVRKAEEVKNMDFYAFSYYY---DRAVDLGLIDESTGGTVRVSDYIEGAKKVCNNMSAGGIKES--PFLCLDLTYISVLLQE-LDFPPDKELKLARQINNAETSWALGAA 429          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Match: entpd3 (ectonucleoside triphosphate diphosphohydrolase 3 [Source:ZFIN;Acc:ZDB-GENE-030131-6186])

HSP 1 Score: 114.005 bits (284), Expect = 9.976e-27
Identity = 130/496 (26.21%), Postives = 220/496 (44.35%), Query Frame = 2
Query:  125 FLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFL--KNDNNMKLHLTDKI------SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQT---MSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKI---------SETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLN--------------------------ASNCFGLKCQNQTVRSECLHPKVKAHFHFGN------RTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVR-LDSYEHFLCLDMSYIVALLHNGYGY--EWFDXXXXXXXXXXXXLSWALGYAISML**YLYYTSALKVLTLMDNFLLYLDLFCIFKLYFI 1447
            F+L  I V+I+      + +       K+ IV+D GSS T ++ +E+   K +N   +  T K        S + L    + +T W+ ++    N+T      IP      TP+++  TAG+R +  T    S  +L  +++ L  S L FK +   I+S ++EG   W+++NYL G F    +         ++TVG LDLGG STQI+FAT++       +K+ L+G +YN+YT  +   G NE   R L                           A   FG +C    V S    PK    F FG       + LV     + SC+   NC   G+   QP  P+ G     +F A + +Y+   +A  +       + +F+    +F + D  KN K+     DS+    C   +Y+  +L +GY +  + ++ +  S  +N  S++W+LGY +++        +  K++ L  N +L+  L  +F +  I
Sbjct:   12 FMLASIAVIISIAVVQTQKKTYVSRGLKYGIVLDAGSSRTTVYLYEWPAEKENNTGVVSQTTKCLVKGPGISDLGLDGDQDQKT-WNSLKECMKNMTEA----IPSHQHNSTPVFLGATAGMRLLHMTNEGRSNDVLTQMKNYL--SSLPFKFQNASIISGQEEGLYGWITVNYLKGNFLEKNLWNAWVHPHGAKTVGSLDLGGASTQIAFATSDDAKGEDIIKVSLYGYEYNIYTHSFLCYGKNEAEKRVLAKLAKEPINWANVKHPCFPTGYNTSIPAEEIFGSECTKNNVPSR-YDPKRSITF-FGQSNPEQCKALVRSIFDLTSCQGTENCSFDGV--YQP--PLNG-----DFTAYAGFYW---TALALKVNGSNSMEKFNTNMKLFCSNDW-KNLKQNYENKDSHLKSFCYSANYVHTILADGYKFNTDNWENLEFSKEVNNTSIAWSLGYMLAL---SNMIPAEGKIIKLPINNVLFTGLLLLFSVLTI 482          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Match: entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:NCBI gene;Acc:677734])

HSP 1 Score: 150.599 bits (379), Expect = 5.860e-40
Identity = 109/385 (28.31%), Postives = 185/385 (48.05%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN-ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF---ATNNVTLIPHS--VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F +      L L  ++  S K  LS F++  +   + +R++ +     A   +P      TP+ ++ TAG+R + +T S  +L+ +R +  +S        V I++   EG  AW+++N+L G+  S++   TVG+LDLGGGSTQI+F     N +   PH     + LF   Y +YT  Y  +G+   R+  L  S       Q Q   S C    VK  + F   TL    K       F  C+ + L ++Q  +          F A S YYY   +  N+       +++  V D    A ++C+  ++     ++ HFLC+D+++I ALL  G+G+E    + ++ ++  + +SW LG    +L
Sbjct:   53 IMFDAGSTGTRIHIYRFKQRARGSHLELEGEVFESIKPGLSAFADQPKKGAATVRLLLD----LAQKEVPSTQWSHTPVVLKATAGLRLLSETQSDALLSEVREVFHESPFLVPENSVSIINGADEGIFAWITVNFLTGRLHSHR---TVGILDLGGGSTQITFLPLTKNTLDQTPHDFLASVELFNSTYRLYTHSYLGLGLKLARLAVLGVSE--DNDQQKQFFHSNCFLHGVKGEWSFAGVTLKYEKKS-DGQSGFDACYSEILPIIQDKLHQVPEMQHSPFYAFS-YYYDRAADANLIDHMHGGVLQ--VYDFAKSAKEVCERTEQS---PTHSHFLCMDLTFITALLKEGFGFEDNTSLQLTKKMYDVEMSWTLGAIFHVL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Match: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 (putative) [Source:NCBI gene;Acc:677735])

HSP 1 Score: 120.553 bits (301), Expect = 4.024e-29
Identity = 110/397 (27.71%), Postives = 182/397 (45.84%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMK-LHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF---ATNNVTLIPHS--VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGK----PIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML**YLYYTSAL 1375
            I+ D GS+GTR+H ++F +  +    L   +  + K  LS +++     +      N L   A   IP+     TP+ ++ TAG+R +    ++K+L+ +R +   S      + V I++   EG  AW+++N+L G   S++   + GMLDLGGGSTQI+F   + N +T  P     +  LF   Y++Y+  Y   G+   R+  +       LK   + V S CL P+ K  F     T  I G+    P+     + +C+ + L ++   +        + F A S YY     A  I  +    L    VKD    A   CK  ++       + FLC+D++YI  LL    G+    ++ ++ +IN +  SWALG          YYTS +
Sbjct:   73 IMFDAGSTGTRIHVYQFSRTPSGAPNLDHEEFRALKPGLSSYADNPLKCA---PGINELLDIAKKEIPQNLWASTPLVLKATAGLRLLPGEKAQKLLDMVRELFKASPFLIGKDSVSIMNGTDEGIFAWITVNFLTGSLTSHEKKHS-GMLDLGGGSTQITFYPYSKNTLTSSPPGYITEFELFHNTYSLYSHSYLGYGLMSARLAIMGGEEGKALKEGEELVTS-CLTPEHKTEFKHAEITYKIKGQKNDEPL-----YVSCYKRVLAVLGGKVERSKEIPNLFFYAFSYYYDRAVDAHLIDPELGGSL---KVKDFDMAAKKECKLIEEA---PGEKPFLCMDLTYITVLLQES-GFPVEKELKLAKKINDVETSWALGAT-------FYYTSIM 445          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Match: ENTPD6 (ectonucleoside triphosphate diphosphohydrolase 6 (putative) [Source:NCBI gene;Acc:677735])

HSP 1 Score: 120.168 bits (300), Expect = 8.123e-29
Identity = 110/395 (27.85%), Postives = 181/395 (45.82%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMK-LHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF---ATNNVTLIPHS--VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGK----PIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML**YLYYTS 1369
            I+ D GS+GTR+H ++F +  +    L   +  + K  LS +++     +      N L   A   IP+     TP+ ++ TAG+R +    ++K+L+ +R +   S      + V I++   EG  AW+++N+L G   S++   + GMLDLGGGSTQI+F   + N +T  P     +  LF   Y++Y+  Y   G+   R+  +       LK   + V S CL P+ K  F     T  I G+    P+     + +C+ + L ++   +        + F A S YY     A  I  +    L    VKD    A   CK  ++       + FLC+D++YI  LL    G+    ++ ++ +IN +  SWALG          YYTS
Sbjct:   92 IMFDAGSTGTRIHVYQFSRTPSGAPNLDHEEFRALKPGLSSYADNPLKCA---PGINELLDIAKKEIPQNLWASTPLVLKATAGLRLLPGEKAQKLLDMVRELFKASPFLIGKDSVSIMNGTDEGIFAWITVNFLTGSLTSHEKKHS-GMLDLGGGSTQITFYPYSKNTLTSSPPGYITEFELFHNTYSLYSHSYLGYGLMSARLAIMGGEEGKALKEGEELVTS-CLTPEHKTEFKHAEITYKIKGQKNDEPL-----YVSCYKRVLAVLGGKVERSKEIPNLFFYAFSYYYDRAVDAHLIDPELGGSL---KVKDFDMAAKKECKLIEE---APGEKPFLCMDLTYITVLLQES-GFPVEKELKLAKKINDVETSWALGAT-------FYYTS 462          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Match: n4bp2l1 (NEDD4 binding protein 2-like 1 [Source:Xenbase;Acc:XB-GENE-1001194])

HSP 1 Score: 105.531 bits (262), Expect = 8.896e-24
Identity = 114/430 (26.51%), Postives = 196/430 (45.58%), Query Frame = 2
Query:  194 PCRRKFIIVVDGGSSGTRLHFFEFL---KNDNNMKLHLTDKISSKVALSKFSNA--RTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSN----------KISETVGMLDLGGGSTQISFATN-NVTLIPHSVKMVLFGQQYNVYTAGYDYMGINE-IRIRYLNA----------SNCF--GLK---CQNQTVRSECLHPKVKAHFHFGNRTLVIGGKP-IKSCRRFCNCFLKGLKMVQPVIPIRGTFD---EMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLD------SYEHFLCLDMSYIVALLHNGYGY--EWFDXXXXXXXXXXXXLSWALGYAISM 1342
            P   K+ IV+D GSS T ++ +E+    +ND  +   + +       +S + +   +   SL + M     + A   IPE+   +TP+Y+  TAG+R +   + TM++++L+ + + L     +F  +   I++ ++EG   W+++NYLLG F  +          K +ET G LDLGG STQI+F +   +    +S+   L+G+ Y++YT  +   G ++ +R++  N+            CF  G +     N    S C+    K        TL I G    + C+R                   G F    +  F A SAYY+++ +  N+T  NE+  ++  VK+ + R    C  P  EV+ D       Y    C   +YI+ LL  GYG+  E ++ I    +I      W LGY +++
Sbjct:   44 PKNIKYGIVLDAGSSHTSVYIYEWPAEKENDTGVVQQINECKVEGNGISSYGHEPLKAGLSLQKCM-----NKARQVIPEKQQRETPVYLGATAGMRLLRLTNATMAEEVLSSVENTLRSFPFDF--QGARIITGQEEGAYGWITINYLLGNFIQDSGWFKYIPNFKPTETSGALDLGGASTQITFESKREIESQENSLHFRLYGKSYDIYTHSFLCYGKDQALRLQIANSIKDATDSILLDPCFNSGYRRNASTNDLYSSPCIS---KLRIPTAPSTLDIRGTGNYQLCKRNVQAIFNRTHCTYSHCSFNGVFQPSLDGTFGAFSAYYFVM-NFLNLT--NEQMSLD-KVKETVERH---CSRPWDEVKKDFPKIKEKYLSEYCFSGTYILNLLEYGYGFSSENWNDIRFLGKIKDSDAGWTLGYMLNL 456          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Match: n4bp2l1 (NEDD4 binding protein 2-like 1 [Source:Xenbase;Acc:XB-GENE-1001194])

HSP 1 Score: 105.531 bits (262), Expect = 9.038e-24
Identity = 114/430 (26.51%), Postives = 196/430 (45.58%), Query Frame = 2
Query:  194 PCRRKFIIVVDGGSSGTRLHFFEFL---KNDNNMKLHLTDKISSKVALSKFSNA--RTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSN----------KISETVGMLDLGGGSTQISFATN-NVTLIPHSVKMVLFGQQYNVYTAGYDYMGINE-IRIRYLNA----------SNCF--GLK---CQNQTVRSECLHPKVKAHFHFGNRTLVIGGKP-IKSCRRFCNCFLKGLKMVQPVIPIRGTFD---EMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLD------SYEHFLCLDMSYIVALLHNGYGY--EWFDXXXXXXXXXXXXLSWALGYAISM 1342
            P   K+ IV+D GSS T ++ +E+    +ND  +   + +       +S + +   +   SL + M     + A   IPE+   +TP+Y+  TAG+R +   + TM++++L+ + + L     +F+     I++ ++EG   W+++NYLLG F  +          K +ET G LDLGG STQI+F +   +    +S+   L+G+ Y++YT  +   G ++ +R++  N+            CF  G +     N    S C+    K        TL I G    + C+R                   G F    +  F A SAYY+++ +  N+T  NE+  ++  VK+ + R    C  P  EV+ D       Y    C   +YI+ LL  GYG+  E ++ I    +I      W LGY +++
Sbjct:   42 PKNIKYGIVLDAGSSHTSVYIYEWPAEKENDTGVVQQINECKVEGNGISSYGHEPLKAGLSLQKCM-----NKARQVIPEKQQRETPVYLGATAGMRLLRLTNATMAEEVLSSVENTLRSFPFDFQG--ARIITGQEEGAYGWITINYLLGNFIQDSGWFKYIPNFKPTETSGALDLGGASTQITFESKREIESQENSLHFRLYGKSYDIYTHSFLCYGKDQALRLQIANSIKDATDSILLDPCFNSGYRRNASTNDLYSSPCIS---KLRIPTAPSTLDIRGTGNYQLCKRNVQAIFNRTHCTYSHCSFNGVFQPSLDGTFGAFSAYYFVM-NFLNLT--NEQMSLD-KVKETVERH---CSRPWDEVKKDFPKIKEKYLSEYCFSGTYILNLLEYGYGFSSENWNDIRFLGKIKDSDAGWTLGYMLNL 454          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Match: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385])

HSP 1 Score: 134.035 bits (336), Expect = 5.074e-34
Identity = 115/393 (29.26%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F       A T   L+ +        A  +IP    E TP+ ++ TAG+R + +  ++ +L  +  I   S        V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F      T   T   +     +F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++VQ  +     +RG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N        S   FLC+D++YI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVLRVVQGKLHQPEEVRGS----AFYAFS-YYYDRAADTHLIDYEKGGVLK--VEDFERKAREVCDNLGS---FSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Match: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385])

HSP 1 Score: 134.035 bits (336), Expect = 5.074e-34
Identity = 115/393 (29.26%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F       A T   L+ +        A  +IP    E TP+ ++ TAG+R + +  ++ +L  +  I   S        V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F      T   T   +     +F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++VQ  +     +RG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N        S   FLC+D++YI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVLRVVQGKLHQPEEVRGS----AFYAFS-YYYDRAADTHLIDYEKGGVLK--VEDFERKAREVCDNLGS---FSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Match: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385])

HSP 1 Score: 134.035 bits (336), Expect = 5.074e-34
Identity = 115/393 (29.26%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F       A T   L+ +        A  +IP    E TP+ ++ TAG+R + +  ++ +L  +  I   S        V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F      T   T   +     +F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++VQ  +     +RG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N        S   FLC+D++YI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVLRVVQGKLHQPEEVRGS----AFYAFS-YYYDRAADTHLIDYEKGGVLK--VEDFERKAREVCDNLGS---FSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Match: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385])

HSP 1 Score: 134.035 bits (336), Expect = 5.074e-34
Identity = 115/393 (29.26%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F       A T   L+ +        A  +IP    E TP+ ++ TAG+R + +  ++ +L  +  I   S        V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F      T   T   +     +F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++VQ  +     +RG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N        S   FLC+D++YI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVLRVVQGKLHQPEEVRGS----AFYAFS-YYYDRAADTHLIDYEKGGVLK--VEDFERKAREVCDNLGS---FSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Match: Entpd5 (ectonucleoside triphosphate diphosphohydrolase 5 [Source:MGI Symbol;Acc:MGI:1321385])

HSP 1 Score: 134.035 bits (336), Expect = 5.074e-34
Identity = 115/393 (29.26%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F       A T   L+ +        A  +IP    E TP+ ++ TAG+R + +  ++ +L  +  I   S        V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F      T   T   +     +F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ + L++VQ  +     +RG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N        S   FLC+D++YI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVLRVVQGKLHQPEEVRGS----AFYAFS-YYYDRAADTHLIDYEKGGVLK--VEDFERKAREVCDNLGS---FSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Match: sp|E1C1L6|ENTP5_CHICK (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Gallus gallus OX=9031 GN=ENTPD5 PE=3 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 3.284e-40
Identity = 115/390 (29.49%), Postives = 193/390 (49.49%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN--ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++    +   L  +I  S K  LS +++   +   S+ R++       A+  +P    + TP+ ++ TAG+R + +  ++ +L+ ++ +  +S      + V I+    EG LAW+++N+L G+  S +   TVG LDLGG STQI+F       +  S         +F   Y +YT  Y   G+   R+  L A N        Q  RS CL  +++A +HFG      GG   +    F  C+L+ LK+V+  +     IRG+     F A S YYY   +  N+    +  ++E  V+D   +A ++C N +   R  S   FLC+D++YI ALL  G+G+     + ++ ++N I  SW LG    +L
Sbjct:   51 IMFDAGSTGTRIHIYTFVQKSPEILPELEGEIFESVKPGLSAYADQPEKGAESVKRLL-----DMAIDAVPPHLWKKTPVVLKATAGLRLLSEEKAQALLSEVKEVFEESPFLVPEDSVSIMDGSYEGILAWITVNFLTGQL-SGQNQHTVGTLDLGGASTQITFLPRFEETLKESPTDFLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALNT--EVADRQMFRSSCLPKQLEAEWHFGGVKYRYGGNK-EGETGFKPCYLEVLKVVKGKLHQPDEIRGS----SFYAFS-YYYDRAADTNLIDYEQGGVLE--VRDFERKAKEVCDNME---RFSSASPFLCMDLTYITALLKEGFGFRDNTLLQLTKKVNNIETSWTLGATFHLL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Match: sp|E1BPW0|ENTP5_BOVIN (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Bos taurus OX=9913 GN=ENTPD5 PE=3 SV=1)

HSP 1 Score: 141.739 bits (356), Expect = 5.939e-36
Identity = 114/393 (29.01%), Postives = 182/393 (46.31%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKN--DNNMKLHLTDK---ISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFS------VKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++   DN  +L + +     S K  LS F +     +        L   A  +IP    + TP+ ++ TAG+R + +  ++ +L  ++ I  KS      + V I+    EG LAWV++N+L G+   +   ETVG LDLGG STQI+F      T   T   +     +F   Y +YT  Y   G+   R+  L A    G+     T RS CL   ++A + FG      GG        F  C+ + L++VQ  +          F A S YY          +  + D++++       V+D   +A ++C N +      S   FLC+D+SYI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   51 IMFDAGSTGTRIHVYTFVQKVPDNTGQLPVLEGEIFDSVKPGLSAFVDQPKQGAET---VQELLEVAKDSIPPSHWKRTPVVLKATAGLRLLPEEKAEALLFEVKEIFKKSPFLVPDDSVSIMDGSYEGILAWVTVNFLTGQLHGHN-QETVGTLDLGGASTQITFLPQFEKTLEQTPRDYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETAGI--DGYTFRSACLPRWLEAEWIFGGVKYQYGGNQEAGEVGFEPCYAEVLRVVQGKLHQPDEVQRGSFYAFSYYY---------DRAVDTDMIDYEKGGVLKVEDFERKAREVCDNLE---NFTSGSPFLCMDLSYITALLKDGFGFASSTVLQLTKKVNNIETGWALGATFHLL 425          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Match: sp|D2GZV9|ENTP5_AILME (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Ailuropoda melanoleuca OX=9646 GN=ENTPD5 PE=3 SV=1)

HSP 1 Score: 137.502 bits (345), Expect = 2.012e-34
Identity = 114/394 (28.93%), Postives = 182/394 (46.19%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRR----FCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFS------VKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  +I  S K  LS F +     +        L   A  ++P    + TP+ ++ TAG+R + +  ++ +L  +R I  KS      + V I+    EG LAWV++N+L G+   +   +TVG LDLGG STQI+F      T   T   +     +F   Y +YT  Y   G+   R+  L A    G+     T RS CL   ++A + FG      GG    +       F  C+ + L++VQ  +       +  F A S YY          +  + D++++       V+D   +A ++C N +K     S   FLC+D+SYI ALL +G+G+     + +S ++N I   WALG    +L
Sbjct:   51 IMFDAGSTGTRIHIYTFVQKIPGQLPILEGEIFESVKPGLSAFVDQPKQGAET---VEELLEVAKDSVPRSHWKRTPVVLKATAGLRLLPEQKAEALLFEVREIFRKSPFLVPDDSVSIMDGSYEGILAWVTVNFLTGQLHGHS-QKTVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGI--DGHTFRSACLPRWLEAEWIFGGVKYQYGGNKEGNEGSGEVGFEPCYAEVLRVVQGKLHQPDEVRKSSFYAFSYYY---------DRAADTDMIDYETGGVLKVEDFERKAREVCDNLEK---FTSGSPFLCMDLSYITALLKDGFGFADSTILQLSKKVNNIETGWALGATFHLL 426          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Match: sp|O75356|ENTP5_HUMAN (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Homo sapiens OX=9606 GN=ENTPD5 PE=1 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 2.266e-34
Identity = 112/390 (28.72%), Postives = 181/390 (46.41%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFS------VKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++        L  ++  S K  LS F +     +        L   A  +IP    + TP+ ++ TAG+R + +  +K +L  ++ I  KS        V I+    EG LAWV++N+L G+   ++  ETVG LDLGG STQI+F      T   T   +     +F   Y +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG        F  C+ + L++V      RG   + E V   ++Y     ++   +  + D++++       V+D   +A ++C N +      S   FLC+D+SYI ALL +G+G+     + ++ ++N I   WALG    +L
Sbjct:   51 IMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAET---VQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHR-QETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEV-GFEPCYAEVLRVV------RGKLHQPEEVQRGSFYAF---SYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLEN---FTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Match: sp|Q6P6S9|ENTP5_RAT (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Rattus norvegicus OX=10116 GN=Entpd5 PE=2 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 2.275e-34
Identity = 116/393 (29.52%), Postives = 185/393 (47.07%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKF-----SNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVL-----FGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++  +     L  +I  S K  LS F       A T   L+ +        A  +IP    + TP+ ++ TAG+R + +  ++ +L  +  I   S      + V I+    EG LAWV++N+L G+    +  ETVG LDLGG STQI+F       +  + K  L     F   + +YT  Y   G+   R+  L A    G      T RS CL   ++A + FG      GG   +    F  C+ +  ++VQ  +     IRG+     F A S YYY   +  ++    +  +++  V+D   +A ++C N +      S   FLC+D+SYI ALL +G+G+E    + ++ ++N I   WALG    +L
Sbjct:   50 IMFDAGSTGTRIHVYTFVQRTSGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEV--------AKDSIPRSHWKRTPVVLKATAGLRLLPEQKAQTLLLEVEEIFKNSPFLVPDDSVSIMDGSYEGILAWVTVNFLTGQLH-GRGQETVGTLDLGGASTQITFLPQLEKTLEQTPKGYLASFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAEG--TDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQ-EGEMGFEPCYAEVRRVVQGKLHQPEEIRGS----SFYAFS-YYYDRAAETHLIDYEKGGVLK--VEDFERKAREVCDNLES---FSSGSPFLCMDLSYITALLKDGFGFEDGTLLQLTKKVNNIETGWALGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Match: A0A099YW50 (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Tinamus guttatus OX=94827 GN=N309_00875 PE=3 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 4.321e-40
Identity = 131/434 (30.18%), Postives = 209/434 (48.16%), Query Frame = 2
Query:  128 LLVLIPVLINEYCCLN----EMEFSE-------PCRRK----FIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN--ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF-----ATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            L +L+ V  +  C L+    EM F E       P   K    + I+ D GS+GTR+H + F++      + L  +I  S K  LS +++   +   S+ R++       A+  +P    + TP+ ++ TAG+R + +  ++ +L  +R +  +S      + V IL    EG LAW+++N+L G+  S +   TVG LDLGG STQI+F      T   T         +F   Y +YT  Y   G+   R+  L A +        QT RS CL  +++A +HFG      GG  I+    F  C+L+ LK+V+  +     IRG+     F A S YYY      N+    E  ++E  V+D   +A ++C N +   R  S   FLC+D++YI ALL  G+G+     + ++ ++N I  SW LG    +L
Sbjct:    6 LPILLAVAFSLSCVLSHSHREMWFQELFPPNTCPINAKPNTFYGIMFDAGSTGTRIHIYTFVQKSPEKLIELEGEIFESVKPGLSAYADQPEKGAESVKRLL-----DMAVDAVPPHLWKKTPVVLKATAGLRLLSEEKAQALLLEVREVFEESPFLVPEDSVSILDGSYEGILAWITVNFLTGQL-SGQNQHTVGTLDLGGASTQITFLPRFEETLKQTPADFLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALDT--KAADGQTFRSSCLPRQLEAEWHFGGVKYRYGGN-IEGETGFKPCYLEVLKIVKGKLHQPDEIRGS----SFYAFS-YYYDRAVDTNLIDYEEGGVLE--VRDFEIKAKEVCDNME---RYSSASPFLCMDLTYITALLKEGFGFRDSTLLQLTKKVNNIETSWTLGATFHLL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Match: E9QI88 (Ectonucleoside triphosphate diphosphohydrolase 5b OS=Danio rerio OX=7955 GN=entpd5b PE=3 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 3.013e-39
Identity = 116/388 (29.90%), Postives = 193/388 (49.74%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN-----ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSV-----KMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI--PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAI 1336
            I+ D GS+GTR+H + F++ + +    L +++  S K  LS +++       T   L+R+        A   +P    + TP+  + TAG+R +    +  +L  ++ +  +S     P+ V I++   EG LAWV++N+L G+ + N   +TVG+LDLGGGSTQI+F   +   I  +      +  +F   Y +YT  Y   GI   R+  L A N  GL  + +  RS CL     A F FG  +  + G  I   R +  C+ + +K+V+ +I  P+    D   F A S YY     A  I +Q    +    V+D    A  +C  P +  +L+    FLC+D++YI  LL +G+G++    + ++ ++  +  SWALG AI
Sbjct:   61 IMFDAGSTGTRIHVYTFIQREPDGLPVLDNEMFHSMKPGLSAYADMPEIAGHTVRQLLRV--------AKKTVPPLEWKRTPLVFRATAGLRLLPAAKAHALLEEVQDVFDESPFYVPPDSVRIMNGTSEGILAWVTVNFLTGRLERN-TEKTVGILDLGGGSTQITFLPKSKKTIEAAPPDYISRFQMFNCSYQLYTHSYLGNGIKAARLSALGALNADGL--EKKLFRSSCLSRSHTAEFSFGGVSYHVSGD-ISGVRGYKACYQELVKVVKGIIKQPLE-LRDSSSFYAFSYYYDHAVEAGLIDEQRGGAV---KVRDFRKTARQVCNRPARHTQLN---QFLCMDLTYITCLLKDGFGFKESTVLQLTKKVRNVETSWALGAAI 429          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Match: A0A5N5LAU8 (Uncharacterized protein OS=Pangasianodon hypophthalmus OX=310915 GN=PHYPO_G00094260 PE=4 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 1.255e-38
Identity = 115/381 (30.18%), Postives = 186/381 (48.82%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVT---LIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKC-QNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAIS 1339
            I+ D GS+GTR+H + FL+ + N    L +++  S K  LS +++              L  FA S +P    + TP+ ++ TAG+R +    +  +L  ++ +   S      + V I++   EG LAWV++N+L G+   N   ++VG+LDLGGGSTQI+F     T      ++ +  +F   Y +YT  + Y G N I+   L A    G K  + +  +S CL    K    FG     + GKP      + +C+ + LK+V+ VI      DEME   I A+ Y    A      +E       V+D   RA ++C    K    +    FLC+D++YI  LL +GYG+E    + ++ +++ +  SWALG  +S
Sbjct:   53 IMFDAGSTGTRIHIYTFLQKEPNRLPVLDNEMFQSLKPGLSAYADMPEKAG---DSVRQLLEFAKSTVPHVEWKQTPVMLKATAGLRMLPPAKAHALLQEVQDVFDDSPFYVPADSVSIMNGTSEGVLAWVTVNFLTGQLYPN-TKKSVGILDLGGGSTQITFLPKKTTERFPADYTARFSMFNTTYKLYT--HSYSG-NGIKAAQLAAIGALGSKAPEGKVFQSSCLPKNYKGKISFGGLIYKVSGKP-GGPTGYKSCYKEMLKVVKGVIQ---EPDEMEDSWIYAFSYYFDHAVEAGLVDEARGGAVKVRDFRKRAKEVC---NKVSMYNPDYPFLCMDLTYITCLLKSGYGFEEETVLELTKKLHNVEASWALGATLS 419          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Match: A0A093FIM6 (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Gavia stellata OX=37040 GN=N328_01684 PE=3 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 1.666e-38
Identity = 117/388 (30.15%), Postives = 189/388 (48.71%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI----PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++      L L  +I  S K  LS +++     +        L   A+  +P    + TP+ ++ TAG+R + +  ++ +L  +R +  +S      + V I+    EG LAW+++N+L G+  S +   TVG LDLGG STQI+F       +  +         +F   Y +YT  Y   G+   R+  L A N   +    Q  RS CL  +++A +HFG      GG   +    F  C+L+ LK+V+  +     IRG+     F A S YYY      N+    E  ++E  VKD   +A ++C N +   R +S   FLC+D++YI ALL  G+G+     + ++ ++N I  SW LG    +L
Sbjct:   51 IMFDAGSTGTRIHIYTFVQKSPENPLELEGEIFESVKPGLSAYADQPEKGAET---VKRLLDMAIDAVPPHLWKTTPVVLKATAGLRLLSEEKAQALLLEVREVFEESPFLVPEDSVSIMDGSYEGILAWITVNFLTGQL-SGQNQHTVGTLDLGGASTQITFLPRFEETLKETPGDFLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALNMEAV--DGQMFRSSCLPKQLEAEWHFGGVKYRYGGNK-EGETGFKPCYLEVLKVVKGKLHQPDEIRGS----SFYAFS-YYYDRAVDINLIDYEEGGVLE--VKDFERKAKEVCDNME---RYNSASPFLCMDLTYITALLKEGFGFRDNTLLQLTKKVNNIETSWTLGATFHLL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Match: A0A091HPN2 (Ectonucleoside triphosphate diphosphohydrolase 5 OS=Calypte anna OX=9244 GN=N300_05671 PE=3 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 2.214e-38
Identity = 119/389 (30.59%), Postives = 189/389 (48.59%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMV-----QPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            I+ D GS+GTR+H + F++      L L  +I  S K  LS +++       M +    L   A+  +P    + TP+ ++ TAG+R + +  ++ +L  +R +  +S      + V I+    EG LAW+++N+L G+  S +   TVG LDLGG STQI+F       +  +         +F   Y +YT  Y   G+   R+  L A N   +    Q  RS CL   ++A +HFG      GG   +    F  C+L+ LK+V     QP   IRG+     F A S YYY      N+    +  ++E  VKD   +A ++C N +   R +S   FLC+D++YI ALL  G+G+     + ++ ++N I  SW LG    +L
Sbjct:   51 IMFDAGSTGTRIHIYTFVQKSPENLLELEGEIFESVKPGLSAYADQPEKEKNMSL---RLLDMAIDAVPPHLWKKTPVVLKATAGLRLLSEEKAQALLLEVREVFEESPFLVPEDSVSIMDGSYEGILAWITVNFLTGQL-SGQNQHTVGTLDLGGASTQITFLPQFEETLKEAPGDFLTSFEMFNSTYKLYTHSYLGFGLKAARLAILGALNMEAV--DGQMFRSSCLPKHLEAEWHFGGVKYRYGGNK-EGETGFKPCYLEVLKVVKGKLHQPT-EIRGS----SFYAFS-YYYDRAVDTNLIDYEQGGILE--VKDFERKAKEVCDNME---RYNSASPFLCMDLTYITALLKEGFGFRDNTLLQLTKKVNNIETSWTLGATFHLL 421          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Match: entpd5b (ectonucleoside triphosphate diphosphohydrolase 5 (inactive) [Source:NCBI gene;Acc:103043327])

HSP 1 Score: 144.821 bits (364), Expect = 4.391e-38
Identity = 113/399 (28.32%), Postives = 196/399 (49.12%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSN--ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTF-DEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML**YLYYTSAL 1375
            + I+ D GS+GTR+H + F++ D +    L +++  S K  LS +++      +SL +++       A S +P    + TP+ ++ TAG+R++    +  +L  ++ +  +       + V I+    EG  AWV++N+L G  + N I  TVG+LDLGGGSTQI+F   +   I +       +  +F   + +YT  Y   GI   RI  L AS   GL+   +  ++ CL    +  F FG  T  + G P +    +  C+ +  K+V+ +I       D   F A S Y++      ++  +N    ++   +D   RA ++C    K    +  + FLC+D++YI  LL +GYG++    + +  ++N +  SWALG AI+    Y  Y S L
Sbjct:   52 YAIMFDAGSTGTRIHVYTFIQKDPDGLPVLDNEMYSSEKPGLSAYADNPENAGYSLRKLLV-----VAKSTVPRVEWKRTPVVLRATAGLRRLPLAKALALLEEVQYVFDEYPFYVPADSVSIMDGTNEGIFAWVTMNFLTGNLRPN-IKRTVGILDLGGGSTQITFLPKSKKTIKNVSADFIARFSMFNTTHELYTHSYSEKGIKAARIAALGASGSEGLEW--KVYKTSCLPKNYEGEFQFGEFTYKVTGNP-EGYTGYKACYQEMKKIVKGIIQQPNELKDGAVFFAFS-YFFDHAVEADLIDENRGGAVQ--TRDFRKRAKEVC---NKMSMFNPMKAFLCMDLTYITCLLKDGYGFKENTVLELIKKVNNVEASWALGAAIN----YFKYISLL 431          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Match: entpd6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:NCBI gene;Acc:103031064])

HSP 1 Score: 131.724 bits (330), Expect = 3.268e-33
Identity = 108/384 (28.12%), Postives = 181/384 (47.14%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEF-LKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFA-----TNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVI----GGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            ++ I+ D GS+GTR+H F+F ++     KL      + K  LS +++   D S   ++   L   A  ++P      TP+ ++ TAG+R +    +  +L+ ++ +   S    +P+ V I+    EG  AW+++N+L+G    ++ + TVGMLDLGGGSTQI+F+     T     I +     +F   +++Y+  Y  +G+   R+  L      G    NQ + S CL P     +        +     G+PI     + +C  K  KM+   +        MEF A S YY     A ++   +E+      V + I  A  +CKN +  V  +    FLCLD++YI  LL    G+    +  ++ +IN +  SWALG
Sbjct:   62 QYGIMFDAGSTGTRIHVFQFQMEPKEAPKLAHETFKAIKPGLSAYAD-DPDKSSAGLL--QLLDVAKESVPAALWASTPLALRATAGLRLLPGDKASHLLDKVKEVFGTSPFLHRPDSVSIMDGTDEGVSAWITVNFLIGGLHGSE-TPTVGMLDLGGGSTQITFSPQDEKTIQTAPIDYVTSFQMFNTSHSLYSHSYLGLGLMSARLAVLGGIE--GQPASNQELISPCLAPDYTGEWEHAEVNYKLKGQKAGEPI-----YESCLSKVEKMIYKKVKKAEEVKNMEFYAFSYYY---DRAVDLGLIDEETGGTIRVSNYIEGAKKVCKNMEAGVGENP---FLCLDLTYISVLLQE-LGFPQDKEFKLARKINDVETSWALG 427          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Match: entpd3 (ectonucleoside triphosphate diphosphohydrolase 3 [Source:NCBI gene;Acc:103030351])

HSP 1 Score: 110.153 bits (274), Expect = 1.726e-25
Identity = 111/432 (25.69%), Postives = 189/432 (43.75%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTD-WSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKI---------SETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNA------------SNCFGLK-----CQNQTVRSECLHPKVKAHFHFG-NRTLVIGGKPI------------KSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNP----KK-----EVRLDSYEHFLCLDMSYIVALLHNGYGY--EWFDXXXXXXXXXXXXLSWALGYAIS 1339
            K+ IV+D GSS T ++ +++     N    ++      V     S    D W  ++   +++T     ++P      TPI++  TAG+R +   ++  S  IL  I+  L     NF  +   I+S ++EG   W+++NYL+G F    +         ++TVG LDLGG STQI+F   +       +++ L+G +YNVYT  +   G NE   + L                C+          ++   SEC      A +    N T   G  P+            KSC+   NC  +G+   QP  P+ G     EF+A + +YY   +A+ +  +    L +F+   + F     C  P    KK     E  L SY    C   +Y+  +L +GY +  + ++ +N    +N+ S++W+LGY ++
Sbjct:   60 KYGIVLDAGSSRTTVYLYQWPAEKENNTGVVSQTTKCLVKGPGISEMNDDSWKYLKTCMDDITK----HVPPSQHSSTPIFLGATAGMRLLHIKNEEASNTILQDIQKYLRSLPFNF--QNASIISGQEEGLYGWITVNYLMGNFLEKNMWNAWVHPHGAKTVGSLDLGGASTQIAFTAPDDATGEDLIRVSLYGYEYNVYTHSFLCYGKNEAEKKVLAELVKSSTDWSRVNHPCYPADYSITMAASEIFDSECTKKSTPASYSPAKNITFFGGSDPVRCKDLVKRIFDFKSCQGKENCSFEGV--YQP--PVSG-----EFMAYAGFYY---TAWALDVKGSNTLKQFNTAMLSF-----CSKPWATLKKNYEITEKHLKSY----CYSANYVHTILADGYKFNDDNWENLNFQKEVNQTSIAWSLGYMLA 464          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Match: entpd2a.1 (ectonucleoside triphosphate diphosphohydrolase 2 [Source:NCBI gene;Acc:103024136])

HSP 1 Score: 97.4413 bits (241), Expect = 3.033e-21
Identity = 108/440 (24.55%), Postives = 187/440 (42.50%), Query Frame = 2
Query:  167 CLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQID---QTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQS--------NKISETVGMLDLGGGSTQISFAT-NNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYL------NASN------CFGLKCQ-----NQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCR------------RFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYI---IKSAFNITKQNEKDLMEFSVK--DIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYE--WFDXXXXXXXXXXXXLSWALGYAISM 1342
             +N  +  EP +  + IV+D GSS T +  +++  N  N    ++      V     S+                  A+  IP+     TPIY+  TAG+R ++     +S +IL  +   L      F  +   IL+ ++EG   WV++NYLL  F          +   +TVG LD GG STQI+F T   V  + + +K+ L+G+ Y++YT  +   G +++  + L        SN      C+          +    + C      + ++ G +  + G    + C              +  C   G+   QP +          F+A +A++YI   +KS   IT  +   L E ++   ++ F  M L K P+++ RL  Y    C    ++  LL  GYG++   F +I+   +  + S+ WALGY +S+
Sbjct:   28 AINSEDIEEPPQYMYGIVLDAGSSHTAMFIYKWPANKQNGTGIVSQHSECDVDGGGISSYAGQKGGAARSLEKCMDHAIQKIPKVRHHQTPIYLGATAGMRLLNISQPKVSDEILKEVGEKL--KTYPFSVKGATILTGQEEGAYGWVTVNYLLENFIKYGFVGHWLSPGKKTVGALDFGGASTQITFETKEKVENVENLMKLRLYGRDYHIYTQSFLCYGRDQMLRKLLAHLVETQGSNDAIIHPCYPADYNVSITLDNVFDTPCTADSKPSPYNAGKKLQIQGSGNYQHCLGNMSHIFSFQTCTYSKCSFNGV--FQPNV-------SGNFMAFAAFFYIHSFLKSTTGITVTSPSLLEEAAITVCNMSFHEM-LQKVPEQQSRLQDY----CAATVFMKVLLLKGYGFDRLSFPQISFQKKAGETSVGWALGYMLSL 451          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Match: entpd1 (ectonucleoside triphosphate diphosphohydrolase 1 [Source:NCBI gene;Acc:103029336])

HSP 1 Score: 94.7449 bits (234), Expect = 1.810e-20
Identity = 98/407 (24.08%), Postives = 173/407 (42.51%), Query Frame = 2
Query:  200 RRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQID---QTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIP-HSVKMVLFGQQYNVYTAGYDYMGINEI-RIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFG---NRTLVIG-GKPIKS-----------CRRFCNCFLKGLKMVQPVIPIRGTFD---EMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGY---EWFDXXXXXXXXXXXXLSWALGYAISM 1342
            + K+ IV+D GSS T ++ +++     N    +    +  V     S   T+ +       +    A S IP     +TP+Y+  TAG+R ++      S+K+L  +  +L     ++  +   I+S ++EG   W+++NYL    +  + S T+G LDLGG STQI+F +      P +S+   L+G  Y+VYT  +   G +++ ++   N       K +   V   C HP  + + +F    N   V G   P K+           C                +    G F    E +F A SA+++++    N+T  +  +  E  +        ++ K     V+ + Y    C   +YI+ LL +GY +    W D   I    N  +  W LGY +++
Sbjct:   46 KYKYGIVLDAGSSHTSVYIYQWPAEKENNTGMVQQMDACNVPGVGISGYSTEPNRAGDSLKSCMDKARSIIPNHRHPETPVYLGATAGMRLLEMKNAAASEKVLESVERVLQTYPFSY--QGARIISGQEEGAFGWITVNYLNESLR--QASGTLGALDLGGASTQITFVSGQKQESPDNSIDFRLYGHDYHVYTHSFLCYGKDQVLKLSLANEIRPVHTKTETIVVEDPCFHPGYRMNKNFQSVFNSPCVTGLSYPEKNFVHMGSGNGTKCHAAVRKVFNDSGCSYSICSFNGIFQPRVEGQFGAFSAFFFVM-DFLNLTTLSLDEAKE-ELGKYCATPWEIIKQNHPNVK-EKYLAEYCFSGTYILTLLEDGYNFTSHNWQDIKFIKKIGNSDA-GWTLGYMLNL 444          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Sea Lamprey
Match: entpd6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:ZFIN;Acc:ZDB-GENE-050417-412])

HSP 1 Score: 125.561 bits (314), Expect = 9.246e-32
Identity = 102/388 (26.29%), Postives = 182/388 (46.91%), Query Frame = 2
Query:  188 SEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRL-AWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS-----VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            + P R  + I+ D GS+GTR+H F F + +      LT ++  S K  LS +++   + S+  I    L + A   IPE   ++TP+ ++ TAG+R +    +  +L  +R++  +S        V+I+    EG + +W+++N+LLG F      +  G+LDLGGGSTQ++F      L+  +         +F + + +Y+  Y  +G+   R+  L        +   + + S CL    K  +   + T +IGG+   S   F  C +K  KM+   +   G   +  F A S Y+     +  I  +         V D   +A  +C   K+ ++    + FLC+D++YI   L  G G+     + ++ +IN +  +WALG
Sbjct:   56 AAPGRMFYGIMFDAGSTGTRIHVFIFKQLNKANLPELTSEVFLSVKPGLSAYAD-HPEQSVQSI--EELLAKAKKAIPETQWQETPVVLRATAGLRLLPGRKADVLLEQVRNVFDRSPFKVPKNSVEIMDGANEGGISSWITINFLLG-FLRGPEDKLFGILDLGGGSTQVTFLPQKQGLLQSASDADVTSFKMFNKTFKIYSHSYLGLGLMSARLAILGGDTG---EPGGRRLLSPCLPSDYKGEWKQSSVTYLIGGQKGAS---FSLCAMKVEKMLSGKVEQPGGIHQQHFYAFSYYFDRAVESGLIAPEGGT----LKVGDYEDKAKSVCDG-KQAIK--GADPFLCMDLAYIAGFLQKGLGFSRDTPLQLAKKINNVETAWALG 426          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003192.1 (pep scaffold:Pmarinus_7.0:GL484058:1986:12022:-1 gene:ENSPMAG00000002913.1 transcript:ENSPMAT00000003192.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 88.9669 bits (219), Expect = 1.375e-19
Identity = 65/224 (29.02%), Postives = 112/224 (50.00%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNN-----MKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLL---------GKFQSNKISETVGMLDLGGGSTQISFATNN-VTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLN 823
            K+ IV+D GSS T L  +E+     N      + HL D +  ++A    S+  +  S            A + +P+    DTP+ +  TAG+R +   D   +K +L+ +R +L     +++     I+S ++EG   W++ NY L         GK+Q    ++ +G LDLGG STQI+F T   +   P S+ + L+G++Y+VY+  Y   G ++   R+L+
Sbjct:   41 KYGIVLDAGSSHTALFVYEWPAEKQNDTGVIAQRHLCD-VDDELAGGGISSYSSSPSGAGESLRACMDKAKAIVPKDRWADTPLALGATAGMRLLEMSDSVAAKAVLSSVREVLGSYPFSYREG--RIISGQEEGTYGWITANYFLYNFIQFTWLGKWQWTTSTKPIGALDLGGASTQITFMTEEPLQGSPDSLTIQLYGRKYHVYSHSYLCYGRDQAIKRFLS 261          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008355.1 (pep scaffold:Pmarinus_7.0:GL477173:2090:22790:1 gene:ENSPMAG00000007537.1 transcript:ENSPMAT00000008355.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.8853 bits (211), Expect = 3.012e-18
Identity = 105/446 (23.54%), Postives = 186/446 (41.70%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLKNDNN-----MKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKF-QSNKIS-------ETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHP----KVKAHFHFG--------------------------NRTLVIGGKPIKSCRRFC-------------NCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDS---YEHF--LCLDMSYIVALLHNGYGYE---WFDXXXXXXXXXXXXL---SWALGYAI 1336
            + +V+D GSS T L  +++  +  N      ++   D     ++  K        SL+  +FN     A   +P +   +TPI V  TAG+R +   +   +++++  +++ L  +   F      IL+ ++EG   WV++NYL G F Q + +S       +TVG LDLGG STQI+F      L   + +  L+G  + V+T  Y   G +E  +R + A+   G    +  V   C H     +++  + FG                           R L+ G      C                 +C   G+   QP  P+ G+     F+A SA+YY++    +  K   +  +++ +++++ R    C  P  EVR  S    +H    C   +Y++ LL +GY +    W +   +       ++    WALGY +
Sbjct:    1 YGVVLDAGSSHTSLFVYQWPADKENDTGVVTQVAHIDVEGGGISSYKDHPEMAGQSLVPSLFN-----ATKLVPPERHHETPISVGATAGMRLLRKQNPEAAERVMESVKTALRATPFLFCS--ARILTGQEEGAFGWVTINYLQGNFLQRDWLSWVRPRGAKTVGALDLGGASTQIAFVPAGGAL-SGTQRFRLYGYDHAVFTHSYLCYGKDEALMR-VAATLSRGNSSSDVEVTFPCYHSGFEERLEVGYMFGKPCTAALKPAVGPRGGGGGAGSGPLQGRVLLRGSGQADQCAEAVAQIFNYSSCAGRKDCTFDGV--YQP--PVSGS-----FMAFSAFYYVM----DFLKLRGEGNVDY-IRNVVKR---FCNKPWNEVRASSQTEQKHLKSYCFSANYLLQLLFHGYKFNLSTWMNIKFVKKVEGIQAIGEAGWALGYML 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Yeast
Match: GDA1 (Guanosine diphosphatase located in the Golgi; involved in the transport of GDP-mannose into the Golgi lumen, converting GDP to GMP after mannose is transferred to substrates; null mutants are defective in sporulation and pre-meiotic S phase entry; orthologous to human ENTPD6, a meiosis-associated non-obstructive azoospermia (NOA) related gene identified in GWAS studies [Source:SGD;Acc:S000000768])

HSP 1 Score: 99.7525 bits (247), Expect = 6.072e-23
Identity = 115/437 (26.32%), Postives = 181/437 (41.42%), Query Frame = 2
Query:  200 RRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISS-KVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSK--LNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKIS-ETVGMLDLGGGSTQISFATNNVTLIPHSVKMV--------LFGQQ-YNVYTAGYDYMGINEIR--IRYLNASNCF-------GLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPI-------------KSCRRFCNCFL-KGLKMVQPVIPIRG--------TFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPK-----------KEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
              K++I++D GS+G+R+H ++F    +   L L +K    +  LS F    TD        + L   AM+ +P +    TP+ V+ TAG+R +    S KIL+ +R  L K       + + V I+  ++EG  AW++ NYLLG   +N     T  + DLGGGSTQI F        P + KMV         FG + Y +Y   +   G+ E R  +  +   N         G   +   + S CL PKV A     N  + +  K                 CR   +  L K  +   P     G        TF E   + I +Y+Y       +        + F++ ++   A  +CK  +               L+S  HF CLD+S+ V+LLH GY      ++    +I    + W LG ++ +L
Sbjct:   90 EHKYVIMIDAGSTGSRVHIYKFDVCTSPPTL-LDEKFDMLEPGLSSFD---TDSVGAANSLDPLLKVAMNYVPIKARSCTPVAVKATAGLRLLGDAKSSKILSAVRDHLEKDYPFPVVEGDGVSIMGGDEEGVFAWITTNYLLGNIGANGPKLPTAAVFDLGGGSTQIVFEPT----FPINEKMVDGEHKFDLKFGDENYTLYQFSHLGYGLKEGRNKVNSVLVENALKDGKILKGDNTKTHQLSSPCLPPKVNAT----NEKVTLESKETYTIDFIGPDEPSGAQCRFLTDEILNKDAQCQSPPCSFNGVHQPSLVRTFKESNDIYIFSYFYDRTRPLGMP-------LSFTLNELNDLARIVCKGEETWNSVFSGIAGSLDELESDSHF-CLDLSFQVSLLHTGYDIPLQRELRTGKKIANKEIGWCLGASLPLL 506          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Yeast
Match: YND1 (Apyrase with wide substrate specificity; helps prevent inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates that inhibit glycotransferases; partially redundant with Gda1p; mediates adenovirus E4orf4-induced toxicity [Source:SGD;Acc:S000000807])

HSP 1 Score: 99.3673 bits (246), Expect = 1.268e-22
Identity = 102/416 (24.52%), Postives = 169/416 (40.62%), Query Frame = 2
Query:  191 EPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALS-KFSNARTDWSL----------------MRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEF--------VDILSTEKEGRLAWVSLNYLLGKFQ--SNKISE--TVGMLDLGGGSTQISFATNN-----------VTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYL---------NASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKP-IKSC-RRFCNCFLKGLK------MVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDII-FRAMDLCKNPKKEVRLDSYEHFL---CLDMSYIVALLHNGY 1255
            E    +F IV+D GSSG+R+H F++   D    LH T++ S  +  S    +   DW+                  +     L  FA + IPE      P+++Q TAG+R + Q +   IL+      L   L    EF        + ++  E EG   W+ LNYL G F   + ++S+  T G +D+GG STQI+FA ++            T+   SV   L  Q+++V+ + +   G N+ R RYL         N ++        + +   C+       F F +    I G    + C +      LK +       +   V   R  F   +F+  S Y+Y     F +  +   D    S+++        +  N  K V     E+FL   C   ++++ +LH G+
Sbjct:    4 ENTNDRFGIVIDAGSSGSRIHVFKW--QDTESLLHATNQDSQSILQSVPHIHQEKDWTFKLNPGLSSFEKKPQDAYKSHIKPLLDFAKNIIPESHWSSCPVFIQATAGMRLLPQDIQSSILDG-----LCQGLKHPAEFLVEDCSAQIQVIDGETEGLYGWLGLNYLYGHFNDYNPEVSDHFTFGFMDMGGASTQIAFAPHDSGEIARHRDDIATIFLRSVNGDL--QKWDVFVSTWLGFGANQARRRYLAQLINTLPENTNDYENDDFSTRNLNDPCMPRGSSTDFEFKDTIFHIAGSGNYEQCTKSIYPLLLKNMPCDDEPCLFNGVHAPRIDFANDKFIGTSEYWYTANDVFKLGGEYNFDKFSKSLREFCNSNWTQILANSDKGVYNSIPENFLKDACFKGNWVLNILHEGF 410          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Nematostella
Match: EDO43911 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX67])

HSP 1 Score: 83.9593 bits (206), Expect = 1.396e-17
Identity = 96/406 (23.65%), Postives = 171/406 (42.12%), Query Frame = 2
Query:  167 CLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKND-----NNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILL---KSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLN--ASNCFGLKCQNQTVRSECLHPKVKAHFHF-GNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFD-EMEFVAISAYYYIIKSAFNITKQNEK-DLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            CL  +      + K+ ++ D GSSGTR   ++ ++       +  +L++     +K  LS F  +      +      L   A   +P Q    TP+Y+  TAG+R +       ++N + + L    KS   FK     ++S   E    WV++N+L+G       +E  G+LD+GG STQ +F TNN   I  +V + L      +Y   Y   G  E R R++    +N    +   + + + C +   +      G   L+ GG   + C          L   +   P       + +F + S + Y  +    ++K  E+ D+     K + F   DL    +KE+  + Y    C  +++I ++L +GY  +   ++     IN + L+W LG  +S L
Sbjct:   16 CLALVSARTIPKAKYAVLFDAGSSGTRCKVYKLIQRQTLHVRDVTQLNVPKPNKAKPGLSSFGESPAG---VGPYLQTLIEGAKKVVPVQYQAQTPVYLFATAGMRLLPVDQKIAVINEVNNFLRDSKKSPFAFKKGNAKVISGIDEATYDWVTVNFLMGALTGESDTE-YGVLDMGGASTQNAFDTNNTQHI--TVVLDLTKGMLPLYAHSYLGYGEQEARKRFIRFLVNN---RRHNRKVITNPCYNSNFEKRVEVDGAEYLMRGGFNPQMCHMIIKSLFFCLSSKKDNCPFHQQPRLKGKFYSFSLFTYAFRETGVVSKNGERIDMETLKRKMLSFCGRDLT---EKEL-ANKYTTPRCFQLNFIYSMLTDGYRVDNSFELYNGESINGLDLNWTLGAMLSAL 408          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Nematostella
Match: EDO42571 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S133])

HSP 1 Score: 60.4622 bits (145), Expect = 1.082e-10
Identity = 42/172 (24.42%), Postives = 84/172 (48.84%), Query Frame = 2
Query:  209 FIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKIS------SKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSIL---LKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF 697
            + ++ D GSSGTR   ++ L+  +++++    +I       +   LS F ++ +    +      L   A++ +P Q     P+YV  TAG+R +    +  ++  +  +L    KS   F+   + ++S + E    WV++N+L+G       +E  G L++GG S+Q +F
Sbjct:    1 YAVMFDAGSSGTRCKVYK-LQTRHSLRISDVSQIKVPKPNKATPGLSFFGDSPSG---VGPYLQPLIDAAINAVPSQYQSQAPVYVFATAGMRLLPDNKATAVIRAVEQMLSNSSKSPFLFQTGNIKVISGKDEAIYDWVTVNFLMGVLTGESSTE-YGALEMGGASSQNAF 167          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Nematostella
Match: EDO31584 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SXJ5])

HSP 1 Score: 43.8986 bits (102), Expect = 7.661e-6
Identity = 25/83 (30.12%), Postives = 41/83 (49.40%), Query Frame = 2
Query:  383 NLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNF---KPEFVDILSTEKEGRLAWVSLNYLLG 622
            +L   A   IP      TP+ ++ TAG+R +    +K +L+ +  +   S  N    +P  V I+    EG  AWV++N+L G
Sbjct:    3 DLLQKAKDVIPVHQWHATPVALKATAGLRLLPVKSAKHLLHEVYEVFSASPFNIPAHQPHCVSIMDGLDEGIFAWVTVNFLTG 85          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Match: entpd5a (ectonucleoside triphosphate diphosphohydrolase 5 (inactive) [Source:NCBI gene;Acc:101165115])

HSP 1 Score: 144.821 bits (364), Expect = 2.826e-37
Identity = 116/385 (30.13%), Postives = 191/385 (49.61%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDK---ISSKVALSKFS-NARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISF---ATNNVTLIP--HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLME-----FSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            ++ D GS+GTR+H ++F++ D  ++L + D     + K  LS++  N     + +R     L   A   +PE+  + TP+ ++ TAG+R + +  ++ IL  +R +  +S        V I++   EG LAWV++N+L G   SN    TVG+LDLGGGSTQI+F   +   +   P  ++ +  LF   Y +YT  Y   G+   R+  L A    GL  +  T  S CL  K +A   FG  T  + G P      +  C+ +    VQ V  I+G F +   V  +  +Y     F+  + NE  L+        V+D   +A ++C    K  +      FLC+DM+YI  LL  G+G++    ++++ ++N +  SWALG
Sbjct:  184 VMFDAGSTGTRIHIYKFIQKDP-VELPVLDSEMYHAIKPGLSEYKYNPEEGGNTIR----QLLKIAKKTVPEEEWKRTPVVLRATAGLRLLTEEQAEGILKEVREVFEESPFYVPSNSVSIMNGINEGVLAWVTVNFLTGHLYSN-TRRTVGILDLGGGSTQITFLPKSKKTIETAPSSYTARFSLFNNTYELYTHSYLKNGLIAARLATLGALGADGLDWKVFT--SPCLPKKYRAEVTFGGNTYKVSGIP-DGYAGYKLCYYE----VQRV--IKGIFHQPYEVKGTNVFYAFSHYFD--RANETGLISERGGTVEVRDFKKKAKEVC---NKMTKYRPISPFLCMDMTYITCLLKEGFGFKDSTVLHLAKKVNNVETSWALG 548          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Match: entpd5b (ectonucleoside triphosphate diphosphohydrolase 5 [Source:NCBI gene;Acc:101158069])

HSP 1 Score: 131.724 bits (330), Expect = 2.346e-33
Identity = 105/386 (27.20%), Postives = 183/386 (47.41%), Query Frame = 2
Query:  215 IVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKI--SSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHS------VKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLC----KNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAI 1336
            ++ D GS+GTR+H + F++ D+     L +++  S K  LS +++A     +       L   A   +P    + TP+ ++ TAG+R +    ++ +L+ I+ +  +S      + V I++   EG LAWVSLN+L G  ++    +TVG+LDLGGGSTQI+F       I  +       ++      + +Y+  Y   GI   R+  L A      + + +  RS CL  K +  + FG     + G+P      +  C+ + LK V+ +I      +        +YYY    A +    +        V+D   RA ++C    KNP           FLC+D++YI  LL +G+G++    + ++ ++N +  SWALG A+
Sbjct:   51 VMFDAGSTGTRIHVYTFIQGDSEPLPVLDNEMFHSVKPGLSAYADAP---EVAGHTVRMLLKVAKKTVPRVDWKRTPLVLRATAGLRLLPAERAQALLDQIQLVFDESPFFVPDDGVSIMNGTDEGILAWVSLNFLTGHLKAQS-KKTVGILDLGGGSTQITFLPTVRKTIEDAPAADFVARLDFLNTTFELYSHSYLGSGIMAARLSTLGALTTD--ESEWRVFRSSCLPGKFRDEWSFGGLVYRVSGEP-GGPEGYKPCYQEVLKAVKGIIHQPYQLESGGVFYAFSYYY--DRAVDAGLIDGLTGGTVQVRDFRKRAKEVCSDMTKNPPA-------SPFLCMDLTYITCLLKDGFGFKDSAALQLTKKVNNVEASWALGAAL 420          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Match: entpd6 (ectonucleoside triphosphate diphosphohydrolase 6 [Source:NCBI gene;Acc:101173329])

HSP 1 Score: 129.798 bits (325), Expect = 1.278e-32
Identity = 111/387 (28.68%), Postives = 179/387 (46.25%), Query Frame = 2
Query:  206 KFIIVVDGGSSGTRLHFFEFLKNDNNMKL--HLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSV-----KMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVI----GGKPI-KSCRRFCNCFLKG-LKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALG 1327
            ++ ++ D GS+GTR+H F+         +  H T K + K  LS +++   D          L   A S++P      TP+ ++ TAG+R +    +K++L  +R I  KS    + + V I+    EG  AW+++N L+G      ++ TVGMLDLGGGSTQI+F+  +   I  S         +F + + VYT  Y  +G+   R+  L  S        +  + S CL P+    +   +    +     G+P+ ++C       L G +K V  V+        M+F A S YY     A N+   +EK      V D    A  +C  P  E + +    FLCLD+ YI  LL   +G+    ++ ++  IN++  SWALG
Sbjct:   63 QYGVMFDAGSTGTRVHIFKLQMKSKEPPIVDHETFK-AIKPGLSAYAD---DPEKCAAGIQELLHVAKSSVPPSMWAKTPLVLKATAGLRLLPGEKAKQLLEKVRQIFHKSPFLSRDDSVSIMDGTDEGISAWITVNVLIGGLSRADLT-TVGMLDLGGGSTQITFSPRDEKTIQMSPIDFIRSFEMFDRTHTVYTHSYLGLGLMSARLTILGGS--VDPPGGSTELVSPCLPPQYSGRWEHADVVFTVKGQKAGEPVFETCLTRVQKVLYGKIKRVSEVV-------SMDFYAFSFYY---DRAVNLGIIDEKLGGAIRVSDYTDAARRVCSGPSAEPQQNP---FLCLDLVYISVLLQE-FGFPPHQQLRLARTINQVETSWALG 428          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Match: entpd1 (ectonucleoside triphosphate diphosphohydrolase 1 [Source:NCBI gene;Acc:101166588])

HSP 1 Score: 100.908 bits (250), Expect = 2.161e-22
Identity = 110/467 (23.55%), Postives = 202/467 (43.25%), Query Frame = 2
Query:  200 RRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSN-ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATN--NVTLIP-HSVKMVLFGQQYNVYTAGYDYMGINE-IRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFG----------------NRTLV-IGGKPIKSCR------------RFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLD-----SYEHFLCLDMSYIVALLHNGYGY--EWFDXXXXXXXXXXXXLSWALGYAISML**Y---------LYYTSALKVLTLMDNFLLYLDLFCIFKLY 1441
            + K+ IV+D GSS T L+ +++    +N    +  K   +VA    S+   T +     + + L   A  NIP++   +TP+Y+  TAG+R +   + + S ++   +   L      F  +   +L+ ++EG   WV++NYL  +       ET G LDLGG STQISF ++  N +  P ++V   L+G  Y +YT  +   G ++ +R+   + +    +      +   C H       H+                 + T + +GG     C+            R+  C   G+   QP  P++G     +F A SAY++++ +  N+T  +        +K ++ +  D C  P  +++ +      Y    C   +YI+ L+  GY +  E +  I    +I      W LGY +++             L YTS + V+T+M   L  + +  ++ L+
Sbjct:   46 KYKYGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLKE-AKENIPQKMHPETPLYLGATAGMRLLKLENSSASDEVFKAVEKTL--RGFPFSYQGARLLAGQEEGAFGWVTVNYLDDRLTQGL--ETTGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQALRLALAHQTK---VNSGPTAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQIVSETFIHLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGI--FQP--PLQG-----QFGAFSAYFFVM-NFLNLTDTS------VPLKTVMQKLSDYCATPWTQIKKEHDIPLKYLAEYCFSGTYILTLMMEGYNFTSETYSSIKYIQKIKNSDAGWTLGYMLNLTNMIPAEAPDSPPLTYTSYVSVVTVMAILLFVIFILILYSLW 488          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Match: entpd1 (ectonucleoside triphosphate diphosphohydrolase 1 [Source:NCBI gene;Acc:101166588])

HSP 1 Score: 97.0561 bits (240), Expect = 2.440e-21
Identity = 95/395 (24.05%), Postives = 170/395 (43.04%), Query Frame = 2
Query:  200 RRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSN-ARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQI---DQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATN--NVTLIP-HSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFG----------------NRTLV-IGGKPIKSCR------------RFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLD-----SYEHFLCLDMSYIVALLHNGYGY 1261
            + K+ IV+D GSS T L+ +++    +N    +  K   +VA    S+   T +     + + L   A  NIP++   +TP+Y+  TAG+R +   + + S ++   +   L      F  +   +L+ ++EG   WV++NYL  +       ET G LDLGG STQISF ++  N +  P ++V   L+G  Y +YT  +   G ++     L  +     K     +   C H       H+                 + T + +GG     C+            R+  C   G+   QP  P++G     +F A SAY++++ +  N+T  +        +K ++ +  D C  P  +++ +      Y    C   +YI+ L+  GY +
Sbjct:   46 KYKYGIVLDAGSSHTSLYIYQWPAEKDNNTGRVEQKHHCQVAGKGISSYTATPYKAGESLISCLKE-AKENIPQKMHPETPLYLGATAGMRLLKLENSSASDEVFKAVEKTL--RGFPFSYQGARLLAGQEEGAFGWVTVNYLDDRLTQGL--ETTGALDLGGASTQISFVSDEYNGSESPDNAVSFRLYGYDYTLYTHSFLCYGKDQA----LRLALAHQTKSGPTAIMDPCFHKGYNETKHYAAVYDSPCVSDQKPQIVSETFIHLGGGNFTQCQEVIKSVFNFTSCRYSRCSFNGI--FQP--PLQG-----QFGAFSAYFFVM-NFLNLTDTS------VPLKTVMQKLSDYCATPWTQIKKEHDIPLKYLAEYCFSGTYILTLMMEGYNF 415          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Match: SMESG000077452.1 (SMESG000077452.1)

HSP 1 Score: 827.009 bits (2135), Expect = 0.000e+0
Identity = 410/412 (99.51%), Postives = 412/412 (100.00%), Query Frame = 2
Query:  110 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDW+LMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKM+LFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDKINISIRINKISLSWALGYAISML
Sbjct:    1 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWNLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMILFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDKINISIRINKISLSWALGYAISML 412          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Match: SMESG000077431.1 (SMESG000077431.1)

HSP 1 Score: 514.998 bits (1325), Expect = 0.000e+0
Identity = 253/412 (61.41%), Postives = 319/412 (77.43%), Query Frame = 2
Query:  110 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            M  IKFL++ I VL NE CC  + E  +PC RKF +VVDGGS+GTRLHFFEF+ N  +MK+  TDKISSKVALSKFS+AR DW LMRIMF NLTSFAMS IP++C  +TPIYVQVTAGVRQI+QTMS KILNHIRSIL K +  FK EFV ILST+KEG LAWVS+N+LLGK Q NK  +TVG+LDLGGGSTQ++FAT NV LIP + +M++F Q+Y VY+ GYDYMG++E RI+Y+NAS+C GL+C NQ +RSECLHP VK +F FGNR++ IGG P+ +  RF NC  KG+ +   + PIR  F +M+FVA+SAYYYII SAFNI K+ + DL  +S+  I+ RA ++CK+PK +   ++++H  CLD++Y+ ALL  GY +  ++ I  S +INKISLSWALGYAIS L
Sbjct:    1 MINIKFLIIFIFVLNNEICCQKKKELLKPCLRKFTVVVDGGSTGTRLHFFEFIGNQTDMKMSFTDKISSKVALSKFSDARADWGLMRIMFINLTSFAMSKIPKECFNNTPIYVQVTAGVRQINQTMSNKILNHIRSILFKLQFKFKAEFVGILSTDKEGILAWVSVNFLLGKLQKNKCLDTVGVLDLGGGSTQVAFATINVNLIPKTTRMIIFNQEYYVYSGGYDYMGMDETRIKYVNASHCLGLQCTNQVMRSECLHPDVKTNFQFGNRSITIGGMPVDNEIRFYNCLTKGINLATNIKPIRQNFRKMKFVAVSAYYYIIMSAFNIKKE-KSDLTSYSLVKILCRATEICKSPKTDT--NNFQHLQCLDITYVYALLSKGYQFHIYENIYFSKKINKISLSWALGYAISKL 409          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Match: SMESG000077449.1 (SMESG000077449.1)

HSP 1 Score: 488.034 bits (1255), Expect = 7.104e-171
Identity = 247/412 (59.95%), Postives = 313/412 (75.97%), Query Frame = 2
Query:  110 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            M YIK L++LI V I E CC N+ +  +PCRRKFIIVVDGGS+GTRLHFFEF + DN + L LTDK SSKVALSKFS+AR +W LMRIMFNNLTSFAMS IP++C  +TPIYVQVTAGVRQI+Q MSKKILNHIR IL+K+   FK EFV ILST KEG LAW+S+NYLLGKFQS+K  ETVG+LDLGGGSTQI+FAT N + I +  K +LFGQQY VY+AGYDYMGINEIR+++  AS CFG KC NQT+RS C+H  +  +F++G+ +L +GGKP     R+ NC ++   ++  V  IR TF +M+FVAISA+Y+I +S F+I   +E DL  ++V  I   A+  C++P K     ++ HFLC+D++Y+ +L+  GYG++  D INISI I  ISLSWALG+AIS+L
Sbjct:    1 MIYIKVLIILITVFIIEICCQNKAKSLKPCRRKFIIVVDGGSTGTRLHFFEFKRMDNQINLILTDKFSSKVALSKFSDARAEWGLMRIMFNNLTSFAMSKIPKECFNNTPIYVQVTAGVRQINQAMSKKILNHIRGILIKTHFKFKSEFVGILSTNKEGLLAWISVNYLLGKFQSDKCLETVGVLDLGGGSTQIAFATVNASFIKNCTKTILFGQQYYVYSAGYDYMGINEIRLKHFRASKCFGSKCHNQTMRSNCMHENLTTNFYYGSMSLKVGGKPNLRSDRYNNCIVQSYNLISHVKQIRHTFWKMDFVAISAFYHIFRSVFHINIGDETDLKSYNVFKIFMYAVANCQDPSKNTL--NFRHFLCIDIAYVNSLISRGYGFDVSDDINISISIKNISLSWALGFAISVL 410          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Match: SMESG000077446.1 (SMESG000077446.1)

HSP 1 Score: 480.33 bits (1235), Expect = 5.529e-168
Identity = 242/412 (58.74%), Postives = 303/412 (73.54%), Query Frame = 2
Query:  110 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            M YIK L+ LIPVLINE CC N+ +  +PC RKFIIVVDGGS+GTRLHFFEF + DN + L LTDK SSKVALSKFS+AR DW LMRIMFNNLTSFAMS IP++C   TP+YVQVTAGVRQ++Q MSKKILNHI   LLKS+  F+PEF  ILS ++EG+ AWVS+N+LLGKFQS+K  +TVG+LDLGGGSTQI+F+TN   LIP + K V+FGQQYNVY+ GYD MG++ +R+ Y  A+NC GLKCQN+ +RSEC+HP V  +FHFGN ++ IGG PIK  RRF  C    L++ +    +R   ++MEFVAISA+Y+II S    + + + D +E++V  I   A   C +P K    D Y+HF CLDMS+I  L    YG+++  K   S +I  +SLSWALGYAIS L
Sbjct:    1 MIYIKLLITLIPVLINEICCQNKAKLLKPCLRKFIIVVDGGSTGTRLHFFEFKQIDNQINLILTDKFSSKVALSKFSDARADWGLMRIMFNNLTSFAMSKIPKECFNSTPMYVQVTAGVRQMNQAMSKKILNHIIGFLLKSQFKFEPEFGGILSPKREGKFAWVSVNFLLGKFQSDKCLDTVGVLDLGGGSTQIAFSTNKAKLIPETTKTVIFGQQYNVYSNGYDNMGMDIMRLEYFEATNCKGLKCQNEVMRSECIHPNVTTNFHFGNVSITIGGIPIKDERRFDECISMTLRIFRDFGILRSYVNDMEFVAISAFYHIISSVIK-SNKTKTDFLEYTVSKIGEEANLRCMSPLKAT--DHYKHFQCLDMSFISTLFWAFYGFDFDYKFKFSKKIKNVSLSWALGYAISTL 409          
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Match: SMESG000077439.1 (SMESG000077439.1)

HSP 1 Score: 473.396 bits (1217), Expect = 2.926e-165
Identity = 240/413 (58.11%), Postives = 300/413 (72.64%), Query Frame = 2
Query:  110 MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFFEFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSNIPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFVDILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNNVTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQTVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCF-LKGLKMVQPVIPIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDLCKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDXXXXXXXXXXXXLSWALGYAISML 1345
            M YIK L+ LIPVLINE CC N+ +  +PC RKFIIVVDGGS+GTRLHFFEF + DN + L LTDK SSKVALS+FS+AR DW LMRIMFNNLTSFAMS IP++C   TP+YVQVTAGVRQ++Q MSKKILNHIR IL+K++  FK EFV +LSTEKEGR AWVS+N+LLGKF+ +K  +TVG+LDLGGGSTQI+F+TN   L+P + K V+FGQQYNVY+ GYD MG++ +R+ Y NA++C GL CQNQ +RS CLHP V  +FHFGN ++ IGG PI++ +R   C  +     + P    R     MEFVAISA+Y+II S     K  + D +E++V  I+      C +P K    D Y+HF CLDMS+I  LL   YG++   K+  S +I  +SLSWALGYAIS L
Sbjct:    1 MVYIKLLITLIPVLINEICCQNKAKLLKPCLRKFIIVVDGGSTGTRLHFFEFKQMDNQINLILTDKFSSKVALSQFSDARADWGLMRIMFNNLTSFAMSKIPKECFNSTPMYVQVTAGVRQMNQAMSKKILNHIRGILIKTQFKFKSEFVGMLSTEKEGRFAWVSVNFLLGKFKRDKSLDTVGVLDLGGGSTQIAFSTNKTELLPKTTKTVIFGQQYNVYSEGYDKMGMDVMRLEYFNATHCKGLTCQNQVMRSPCLHPNVTTNFHFGNMSITIGGTPIETDKRHLTCLAIAYYTFIDPKKLTR-YISHMEFVAISAFYHIINSVIKSNKA-KSDFLEYTVTRIVEETNLRCMSPLKAT--DRYKHFQCLDMSFISVLLWGFYGFDNNYKLKFSKKIKNVSLSWALGYAISTL 409          
The following BLAST results are available for this feature:
BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENTPD54.719e-3528.72ectonucleoside triphosphate diphosphohydrolase 5 (... [more]
ENTPD51.999e-3429.01ectonucleoside triphosphate diphosphohydrolase 5 (... [more]
ENTPD63.000e-2625.98ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
ENTPD63.263e-2625.98ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
ENTPD63.482e-2625.98ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
uda-17.902e-2424.41Nucleoside-diphosphatase uda-1 [Source:UniProtKB/... [more]
mig-238.548e-1622.65Nucleoside-diphosphatase mig-23 [Source:UniProtKB... [more]
ntp-14.124e-1328.81Nucleoside-triphosphatase ntp-1 [Source:UniProtKB... [more]
ntp-14.246e-1328.81Nucleoside-triphosphatase ntp-1 [Source:UniProtKB... [more]
ntp-14.246e-1328.81Nucleoside-triphosphatase ntp-1 [Source:UniProtKB... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NTPase9.581e-3025.26gene:FBgn0024947 transcript:FBtr0077683[more]
NTPase1.167e-2925.26gene:FBgn0024947 transcript:FBtr0332459[more]
NTPase1.782e-2925.26gene:FBgn0024947 transcript:FBtr0332460[more]
NTPase3.373e-1626.10gene:FBgn0024947 transcript:FBtr0077680[more]
NTPase3.373e-1626.10gene:FBgn0024947 transcript:FBtr0077682[more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
entpd5b1.346e-4229.90ectonucleoside triphosphate diphosphohydrolase 5b ... [more]
entpd5b4.307e-3827.75ectonucleoside triphosphate diphosphohydrolase 5b ... [more]
entpd5a9.276e-3629.34ectonucleoside triphosphate diphosphohydrolase 5a ... [more]
entpd61.974e-3229.24ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
entpd39.976e-2726.21ectonucleoside triphosphate diphosphohydrolase 3 [... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
entpd55.860e-4028.31ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
ENTPD64.024e-2927.71ectonucleoside triphosphate diphosphohydrolase 6 (... [more]
ENTPD68.123e-2927.85ectonucleoside triphosphate diphosphohydrolase 6 (... [more]
n4bp2l18.896e-2426.51NEDD4 binding protein 2-like 1 [Source:Xenbase;Acc... [more]
n4bp2l19.038e-2426.51NEDD4 binding protein 2-like 1 [Source:Xenbase;Acc... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Entpd55.074e-3429.26ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
Entpd55.074e-3429.26ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
Entpd55.074e-3429.26ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
Entpd55.074e-3429.26ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
Entpd55.074e-3429.26ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|E1C1L6|ENTP5_CHICK3.284e-4029.49Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
sp|E1BPW0|ENTP5_BOVIN5.939e-3629.01Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
sp|D2GZV9|ENTP5_AILME2.012e-3428.93Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
sp|O75356|ENTP5_HUMAN2.266e-3428.72Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
sp|Q6P6S9|ENTP5_RAT2.275e-3429.52Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A099YW504.321e-4030.18Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
E9QI883.013e-3929.90Ectonucleoside triphosphate diphosphohydrolase 5b ... [more]
A0A5N5LAU81.255e-3830.18Uncharacterized protein OS=Pangasianodon hypophtha... [more]
A0A093FIM61.666e-3830.15Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
A0A091HPN22.214e-3830.59Ectonucleoside triphosphate diphosphohydrolase 5 O... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
entpd5b4.391e-3828.32ectonucleoside triphosphate diphosphohydrolase 5 (... [more]
entpd63.268e-3328.13ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
entpd31.726e-2525.69ectonucleoside triphosphate diphosphohydrolase 3 [... [more]
entpd2a.13.033e-2124.55ectonucleoside triphosphate diphosphohydrolase 2 [... [more]
entpd11.810e-2024.08ectonucleoside triphosphate diphosphohydrolase 1 [... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
entpd69.246e-3226.29ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
ENSPMAT00000003192.11.375e-1929.02pep scaffold:Pmarinus_7.0:GL484058:1986:12022:-1 g... [more]
ENSPMAT00000008355.13.012e-1823.54pep scaffold:Pmarinus_7.0:GL477173:2090:22790:1 ge... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
GDA16.072e-2326.32Guanosine diphosphatase located in the Golgi; invo... [more]
YND11.268e-2224.52Apyrase with wide substrate specificity; helps pre... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO439111.396e-1723.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO425711.082e-1024.42Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO315847.661e-630.12Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
entpd5a2.826e-3730.13ectonucleoside triphosphate diphosphohydrolase 5 (... [more]
entpd5b2.346e-3327.20ectonucleoside triphosphate diphosphohydrolase 5 [... [more]
entpd61.278e-3228.68ectonucleoside triphosphate diphosphohydrolase 6 [... [more]
entpd12.161e-2223.55ectonucleoside triphosphate diphosphohydrolase 1 [... [more]
entpd12.440e-2124.05ectonucleoside triphosphate diphosphohydrolase 1 [... [more]
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BLAST of Ectonucleoside triphosphate diphosphohydrolase 5 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000077452.10.000e+099.51SMESG000077452.1[more]
SMESG000077431.10.000e+061.41SMESG000077431.1[more]
SMESG000077449.17.104e-17159.95SMESG000077449.1[more]
SMESG000077446.15.529e-16858.74SMESG000077446.1[more]
SMESG000077439.12.926e-16558.11SMESG000077439.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024795 ID=SMED30024795|Name=Ectonucleoside triphosphate diphosphohydrolase 5|organism=Schmidtea mediterranea sexual|type=transcript|length=1471bp
TTTTTGTTTAAATTAGTTAAAAGGATAATATTAGGTTTTTGTTCTAATTT
TACTTCGAATACTTTGATGATAGTTTCTCAATCTTTTGTTATAAAGATTT
TCTCAAAACATGACCTATATAAAATTTCTATTGGTTTTGATTCCTGTGCT
AATTAATGAATATTGCTGTTTAAATGAAATGGAATTCTCAGAGCCTTGTA
GAAGAAAATTCATAATTGTAGTTGACGGAGGAAGTTCTGGAACAAGATTG
CATTTCTTTGAATTTTTAAAAAATGACAATAACATGAAATTACATTTAAC
GGACAAAATTTCTTCAAAAGTAGCTTTATCAAAATTTTCAAATGCGCGTA
CAGATTGGAGTCTAATGAGAATAATGTTTAACAATTTGACCTCCTTTGCA
ATGTCAAATATTCCAGAACAGTGCATCGAAGATACTCCGATATATGTCCA
AGTAACGGCTGGAGTTCGACAAATTGATCAAACCATGAGTAAAAAGATTT
TGAATCATATCAGAAGTATTCTTCTTAAATCTAAATTGAATTTCAAGCCT
GAATTTGTTGACATATTAAGCACTGAAAAAGAAGGAAGATTAGCTTGGGT
AAGCCTGAACTATTTGCTAGGAAAGTTTCAAAGTAATAAAATCTCAGAAA
CCGTTGGCATGCTTGATCTCGGAGGGGGCTCAACACAAATATCATTCGCT
ACAAATAATGTTACTTTAATACCACATAGTGTTAAAATGGTACTTTTTGG
ACAACAATATAATGTGTATACCGCTGGTTATGATTACATGGGAATTAATG
AAATACGAATCAGGTATTTGAATGCTTCAAATTGTTTTGGATTAAAATGC
CAAAATCAAACAGTGAGATCTGAATGTTTGCACCCAAAGGTAAAAGCTCA
TTTTCATTTTGGTAACAGAACTCTCGTTATCGGTGGAAAGCCGATCAAAA
GTTGCCGACGGTTTTGTAATTGTTTTCTAAAAGGCCTCAAAATGGTTCAA
CCTGTGATTCCCATTAGAGGAACATTTGATGAAATGGAATTTGTCGCCAT
TTCTGCATATTATTATATAATAAAGTCCGCATTTAATATTACTAAACAAA
ACGAAAAAGATTTAATGGAATTTTCAGTCAAAGACATTATTTTTCGTGCC
ATGGATCTTTGTAAAAATCCTAAGAAAGAAGTCAGACTTGATAGTTACGA
ACATTTCCTATGCTTAGACATGTCTTATATTGTTGCTCTACTTCACAATG
GCTATGGATACGAGTGGTTTGATAAAATAAACATTTCAATACGGATAAAC
AAAATAAGCTTAAGTTGGGCTCTAGGATATGCTATTTCAATGTTATAATG
ATATTTATATTATACCTCCGCTTTGAAAGTTTTAACATTAATGGATAATT
TTCTATTATATTTAGATTTATTCTGTATATTCAAATTATATTTCATTTAC
TCTGGGTATGATGATGTCATG
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protein sequence of SMED30024795-orf-1

>SMED30024795-orf-1 ID=SMED30024795-orf-1|Name=SMED30024795-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=413bp
MTYIKFLLVLIPVLINEYCCLNEMEFSEPCRRKFIIVVDGGSSGTRLHFF
EFLKNDNNMKLHLTDKISSKVALSKFSNARTDWSLMRIMFNNLTSFAMSN
IPEQCIEDTPIYVQVTAGVRQIDQTMSKKILNHIRSILLKSKLNFKPEFV
DILSTEKEGRLAWVSLNYLLGKFQSNKISETVGMLDLGGGSTQISFATNN
VTLIPHSVKMVLFGQQYNVYTAGYDYMGINEIRIRYLNASNCFGLKCQNQ
TVRSECLHPKVKAHFHFGNRTLVIGGKPIKSCRRFCNCFLKGLKMVQPVI
PIRGTFDEMEFVAISAYYYIIKSAFNITKQNEKDLMEFSVKDIIFRAMDL
CKNPKKEVRLDSYEHFLCLDMSYIVALLHNGYGYEWFDKINISIRINKIS
LSWALGYAISML*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0005524ATP binding
GO:0016787hydrolase activity
GO:0004382guanosine-diphosphatase activity
GO:0017110nucleoside-diphosphatase activity
GO:0045134uridine-diphosphatase activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000407GDA1_CD39_NTPase
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
GO:0005783endoplasmic reticulum
GO:0070062extracellular exosome
Vocabulary: biological process
TermDefinition
GO:0006486protein glycosylation
GO:0006487protein N-linked glycosylation
GO:0008283cell proliferation
GO:0014066regulation of phosphatidylinositol 3-kinase signaling
GO:0016049cell growth
GO:0045821positive regulation of glycolytic process
GO:0046034ATP metabolic process
GO:0051084'de novo' posttranslational protein folding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3DG3DSA:3.30.420.40coord: 33..409
e-value: 4.5E-65
score: 222.2
NoneNo IPR availableGENE3DG3DSA:3.30.420.150coord: 154..397
e-value: 4.5E-65
score: 222.2
NoneNo IPR availablePANTHERPTHR11782:SF83NTPASE, ISOFORM Fcoord: 8..412
NoneNo IPR availableCDDcd00012NBD_sugar-kinase_HSP70_actincoord: 36..199
e-value: 6.73009E-7
score: 47.1983
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..20
score: 0.584
IPR000407Nucleoside phosphatase GDA1/CD39PFAMPF01150GDA1_CD39coord: 31..410
e-value: 2.8E-53
score: 181.1
IPR000407Nucleoside phosphatase GDA1/CD39PANTHERPTHR11782ADENOSINE/GUANOSINE DIPHOSPHATASEcoord: 8..412