Transgelin

Overview


Name	Transgelin
Smed ID	SMED30024775
Length (bp)	898

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Transgelin (SMED30024775) t-SNE clustered cells

Violin plots show distribution of expression levels for Transgelin (SMED30024775) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Transgelin (SMED30024775) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Transgelin (SMED30024775) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024775

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 7

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
Smed sexual biotype	SMED30024775	h1SMcG0008203	Contig42861	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30024775	h1SMcG0008203	Contig42861	newmark_ests	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30024775	h1SMcG0008203	dd_Smed_v4_1512_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30024775	h1SMcG0008203	dd_Smed_v4_1512_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30024775	h1SMcG0008203	dd_Smed_v4_1512_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
pharynx musculature	SMED30024775	h1SMcG0008203	dd_Smed_v6_1512_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
musculature system	SMED30024775	h1SMcG0008203	dd_Smed_v6_1512_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Transgelin vs. Ensembl Human
Match: TAGLN3 (transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868])

HSP 1 Score: 149.443 bits (376), Expect = 1.046e-43
Identity = 87/199 (43.72%), Postives = 126/199 (63.32%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS----KSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K D + E + +DWI     E ++        ++  L  G +LCK++N L P     I KI+E S M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A +N+RGF++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISE-SKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS----KSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K D + E + +DWI     E ++        ++  L  G +LCK++N L P     I KI+E S M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A +N+RGF++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISE-SKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS----KSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K D + E + +DWI     E ++        ++  L  G +LCK++N L P     I KI+E S M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A +N+RGF++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISE-SKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS----KSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K D + E + +DWI     E ++        ++  L  G +LCK++N L P     I KI+E S M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A +N+RGF++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISE-SKMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198

[Close]

BLAST of Transgelin vs. Ensembl Human
Match: CNN1 (calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155])

HSP 1 Score: 150.984 bits (380), Expect = 4.043e-43
Identity = 86/189 (45.50%), Postives = 121/189 (64.02%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +EQE  +WIE + G ++ +  ++ D L+ G++LC+ +NKLQPG +KKINE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F    ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGN--NFMDGLKDGIILCEFINKLQPGSVKKINE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERKFEPGKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. Ensembl Celegans
Match: cpn-1 (CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EFB5])

HSP 1 Score: 125.561 bits (314), Expect = 5.177e-35
Identity = 73/184 (39.67%), Postives = 113/184 (61.41%), Query Frame = 2

Query:   89 GLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNL----RSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            G++ + ++K+ EK D N   E + W++ + G+  D+ +   DNL    + G LLC + N L+PG +KK+N  S M FK MENI+ F +  ++Y V  +++FQTVDLYE +D   V   L +L R  + +   +G  LGPK A  ++R +T E +K G N+IGLQMG+N+GA+ SG+  G  R +
Sbjct:   14 GIALEAQQKIYEKYDKNLAGEILQWVQNVTGQSFDT-QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVN-TSAMAFKKMENISFFLKFAEEY-VQKSELFQTVDLYEGQDPNAVLICLASLARKSEKNFGRSG--LGPKEAQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192

[Close]

Query:   89 GLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNL----RSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            G++ + ++K+ EK D N   E + W++ + G+  D+ +   DNL    + G LLC + N L+PG +KK+N  S M FK MENI+ F +  ++Y V  +++FQTVDLYE +D   V   L +L R  + +   +G  LGPK A  ++R +T E +K G N+IGLQMG+N+GA+ SG+  G  R +
Sbjct:   14 GIALEAQQKIYEKYDKNLAGEILQWVQNVTGQSFDT-QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVN-TSAMAFKKMENISFFLKFAEEY-VQKSELFQTVDLYEGQDPNAVLICLASLARKSEKNFGRSG--LGPKEAQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192

[Close]

Query:   89 GLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNL----RSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            G++ + ++K+ EK D N   E + W++ + G+  D+ +   DNL    + G LLC + N L+PG +KK+N  S M FK MENI+ F +  ++Y V  +++FQTVDLYE +D   V   L +L R  + +   +G  LGPK A  ++R +T E +K G N+IGLQMG+N+GA+ SG+  G  R +
Sbjct:   14 GIALEAQQKIYEKYDKNLAGEILQWVQNVTGQSFDT-QGDADNLVKVFQDGSLLCTLANSLKPGSVKKVN-TSAMAFKKMENISFFLKFAEEY-VQKSELFQTVDLYEGQDPNAVLICLASLARKSEKNFGRSG--LGPKEAQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192

[Close]

BLAST of Transgelin vs. Ensembl Celegans
Match: cpn-2 (Transgelin [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU9])

HSP 1 Score: 122.094 bits (305), Expect = 1.636e-33
Identity = 74/197 (37.56%), Postives = 106/197 (53.81%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL-------DSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEY-NGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN G +YGLS +++KK + +    +  E + WIE + GE+        +SS    + L+ GV+LCK++ KL P      N+   M F +MENI+ F  A K++GV     FQTVDLYE K   +V + L  L    Q    +   P    KLA  + R F +  ++RG  +I LQ GTN+ ASQ GM+ +G  R I
Sbjct:    1 MANHGPSYGLSRELQKKNDARFVLEEAIEVLKWIENVTGERFSFDVTTCESSTDVSNLLKDGVMLCKLIEKLDPSCRVVYNKKPKMAFPMMENISNFLAAAKQFGVMEISCFQTVDLYENKQCYKVIECLRLLAAVAQSRSSHLEHPAWVVKLAQSSPRQFPEAVMRRGEMVIPLQYGTNKCASQKGMSPYGLPRQI 197

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL-------DSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEY-NGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN G +YGLS +++KK + +    +  E + WIE + GE+        +SS    + L+ GV+LCK++ KL P      N+   M F +MENI+ F  A K++GV     FQTVDLYE K   +V + L  L    Q    +   P    KLA  + R F +  ++RG  +I LQ GTN+ ASQ GM+ +G  R I
Sbjct:    1 MANHGPSYGLSRELQKKNDARFVLEEAIEVLKWIENVTGERFSFDVTTCESSTDVSNLLKDGVMLCKLIEKLDPSCRVVYNKKPKMAFPMMENISNFLAAAKQFGVMEISCFQTVDLYENKQCYKVIECLRLLAAVAQSRSSHLEHPAWVVKLAQSSPRQFPEAVMRRGEMVIPLQYGTNKCASQKGMSPYGLPRQI 197

[Close]

BLAST of Transgelin vs. Ensembl Fly
Match: Mp20 (gene:FBgn0002789 transcript:FBtr0087745)

HSP 1 Score: 197.978 bits (502), Expect = 3.577e-63
Identity = 97/179 (54.19%), Postives = 126/179 (70.39%), Query Frame = 2

Query:   92 LSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            L   V+ K+  KR+P  ++EA +WIEAI+ EK  + +SYED L+ G +LCK++N L P  + K+N +S   FK MENIN FQ+A+K+YGVP  DVFQTVDLYEKKDIA VT T+FALGR    H ++ GP LGPK A E KR FT+E +K G  I+GLQ G+N+GA+Q+G   G  R I
Sbjct:    3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN-SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKI 180

[Close]

BLAST of Transgelin vs. Ensembl Fly
Match: Mp20 (gene:FBgn0002789 transcript:FBtr0345532)

HSP 1 Score: 197.978 bits (502), Expect = 4.386e-63
Identity = 97/179 (54.19%), Postives = 126/179 (70.39%), Query Frame = 2

Query:   92 LSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            L   V+ K+  KR+P  ++EA +WIEAI+ EK  + +SYED L+ G +LCK++N L P  + K+N +S   FK MENIN FQ+A+K+YGVP  DVFQTVDLYEKKDIA VT T+FALGR    H ++ GP LGPK A E KR FT+E +K G  I+GLQ G+N+GA+Q+G   G  R I
Sbjct:    3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN-SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKI 180

[Close]

BLAST of Transgelin vs. Ensembl Fly
Match: CG5023 (gene:FBgn0038774 transcript:FBtr0083866)

HSP 1 Score: 180.259 bits (456), Expect = 2.466e-56
Identity = 85/158 (53.80%), Postives = 117/158 (74.05%), Query Frame = 2

Query:  128 RDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSG 601
            R+  QEQE ++W+ A++GEK+ S + YED L+ G+ LCK+ NKL PG +KKI E  T  F++MENI  FQ A+KKYGVP  ++FQT DL+E+++I QVT +L+ALGR  Q HPEY GP LGPK+A +N+R FT+E ++     + LQMG N+GASQ+G
Sbjct:    4 RNKEQEQEVLNWVFAVIGEKVPSGQ-YEDILKDGIWLCKLANKLAPGSVKKIQERGTN-FQLMENIQRFQAAVKKYGVPEEEIFQTADLFERRNIPQVTLSLYALGRITQKHPEYTGPTLGPKMADKNERSFTEEQLRAHEGELNLQMGFNKGASQAG 159

[Close]

BLAST of Transgelin vs. Ensembl Fly
Match: Chd64 (gene:FBgn0035499 transcript:FBtr0073270)

HSP 1 Score: 160.229 bits (404), Expect = 2.559e-48
Identity = 80/192 (41.67%), Postives = 125/192 (65.10%), Query Frame = 2

Query:   62 IMANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS---KSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            + +N+    G +A+ ++K+N K      QE+++WI+A+  E +++S    ++ + L+ GV+LCK+ N LQPG IKKINE S M FK MENI+AF    K +GVP  + FQ+VDL+E++++  V   L +LGR       +N P +GPK A +N R F+ E ++ G+N+I LQ G+N+GA+QSG+ FG  R +
Sbjct:    1 MASNRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANALQPGSIKKINE-SKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKAS---NFNKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGINFGNTRHM 188

[Close]

BLAST of Transgelin vs. Ensembl Fly
Match: Chd64 (gene:FBgn0035499 transcript:FBtr0310531)

HSP 1 Score: 150.984 bits (380), Expect = 6.906e-45
Identity = 77/177 (43.50%), Postives = 116/177 (65.54%), Query Frame = 2

Query:  107 KKKLNEKRDPNQEQEAIDWIEAILGEKLDSS---KSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            + K+N K      QE+++WI+A+  E +++S    ++ + L+ GV+LCK+ N LQPG IKKINE S M FK MENI+AF    K +GVP  + FQ+VDL+E++++  V   L +LGR       +N P +GPK A +N R F+ E ++ G+N+I LQ G+N+GA+QSG+ FG  R +
Sbjct:    3 QSKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANALQPGSIKKINE-SKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKAS---NFNKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGINFGNTRHM 175

[Close]

BLAST of Transgelin vs. Ensembl Zebrafish
Match: tagln2 (transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2])

HSP 1 Score: 149.828 bits (377), Expect = 4.446e-44
Identity = 85/200 (42.50%), Postives = 129/200 (64.50%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD----SSKSYEDNLRSGVLLCKVMNKL----QPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V+ K+++K DP  E   + WI +  GE +       + ++  L+ G +LC+++N L    +P  +KKI ++S+M FK ME I+ F  A ++YG+  +D+FQTVDL+E KD+A V  TL +LG       +  Y G P   PK + EN+R F++E +K G ++IGLQMGTN+GASQ+GMT +G+ R I
Sbjct:    1 MANKGPSYGLSREVQSKIDKKYDPELEGRLVQWIVSQCGEAIGKPQPGKQGFQQWLKDGCILCELINSLFKDSKP--VKKI-QSSSMAFKQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQI 197

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD----SSKSYEDNLRSGVLLCKVMNKL----QPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V+ K+++K DP  E   + WI +  GE +       + ++  L+ G +LC+++N L    +P  +KKI ++S+M FK ME I+ F  A ++YG+  +D+FQTVDL+E KD+A V  TL +LG       +  Y G P   PK + EN+R F++E +K G ++IGLQMGTN+GASQ+GMT +G+ R I
Sbjct:    1 MANKGPSYGLSREVQSKIDKKYDPELEGRLVQWIVSQCGEAIGKPQPGKQGFQQWLKDGCILCELINSLFKDSKP--VKKI-QSSSMAFKQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQI 197

[Close]

BLAST of Transgelin vs. Ensembl Zebrafish
Match: tagln2 (transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2])

HSP 1 Score: 149.828 bits (377), Expect = 9.365e-44
Identity = 85/200 (42.50%), Postives = 129/200 (64.50%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD----SSKSYEDNLRSGVLLCKVMNKL----QPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V+ K+++K DP  E   + WI +  GE +       + ++  L+ G +LC+++N L    +P  +KKI ++S+M FK ME I+ F  A ++YG+  +D+FQTVDL+E KD+A V  TL +LG       +  Y G P   PK + EN+R F++E +K G ++IGLQMGTN+GASQ+GMT +G+ R I
Sbjct:   16 MANKGPSYGLSREVQSKIDKKYDPELEGRLVQWIVSQCGEAIGKPQPGKQGFQQWLKDGCILCELINSLFKDSKP--VKKI-QSSSMAFKQMEQISQFLTAAERYGITKSDIFQTVDLWEGKDLAAVQMTLLSLGSLAVTKDDGCYRGDPAWFPKKSQENRREFSEEQMKEGQSVIGLQMGTNKGASQAGMTGYGRPRQI 212

[Close]

BLAST of Transgelin vs. Ensembl Zebrafish
Match: tagln (transgelin [Source:ZFIN;Acc:ZDB-GENE-070912-1])

HSP 1 Score: 146.747 bits (369), Expect = 7.289e-43
Identity = 86/197 (43.65%), Postives = 128/197 (64.97%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL---DSSK-SYEDNLRSGVLLCKVMNKL-QPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS QV+ K+ +K DP  E   ++W+ A  G  +   D+ K  ++  L+ G +LC+++N L +   +KKI ++S+M FK ME ++ F  A ++YGV  TD+FQTVDL+E KD+A V +TL ALG       +  + G P    K A EN+R F+ + +K G N+IGLQMG+N+GASQ+GMT +G+ R I
Sbjct:    1 MANKGPSYGLSRQVQDKIEQKYDPELELRLVEWLVAQCGSAVGRPDAGKLGFQAWLKDGCVLCELINSLSKEKPVKKI-QSSSMAFKQMEQVSQFLNAAEQYGVAKTDIFQTVDLWEGKDLAAVQRTLMALGSIAVTKEDGAFRGDPNWFFKKAQENRRDFSDDQMKEGKNVIGLQMGSNRGASQAGMTGYGRPRQI 196

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL---DSSK-SYEDNLRSGVLLCKVMNKL-QPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS QV+ K+ +K DP  E   ++W+ A  G  +   D+ K  ++  L+ G +LC+++N L +   +KKI ++S+M FK ME ++ F  A ++YGV  TD+FQTVDL+E KD+A V +TL ALG       +  + G P    K A EN+R F+ + +K G N+IGLQMG+N+GASQ+GMT +G+ R I
Sbjct:    1 MANKGPSYGLSRQVQDKIEQKYDPELELRLVEWLVAQCGSAVGRPDAGKLGFQAWLKDGCVLCELINSLSKEKPVKKI-QSSSMAFKQMEQVSQFLNAAEQYGVAKTDIFQTVDLWEGKDLAAVQRTLMALGSIAVTKEDGAFRGDPNWFFKKAQENRRDFSDDQMKEGKNVIGLQMGSNRGASQAGMTGYGRPRQI 196

[Close]

BLAST of Transgelin vs. Ensembl Xenopus
Match: tagln2 (transgelin 2 [Source:NCBI gene;Acc:394981])

HSP 1 Score: 153.295 bits (386), Expect = 3.197e-45
Identity = 89/197 (45.18%), Postives = 125/197 (63.45%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDS-----SKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G AYGLS +V++K+++K D + E   + WI+A  G    S       + +  L+ G +L  ++N L PG I K+ + S M FK ME I+ F +A ++YG+P +D+FQTVDL+E KD+A V +TL  LG       +  + G P   PK + ENKR F+Q+ +K G NIIGLQMGTN+GASQSGMT +G  R I
Sbjct:    1 MANKGPAYGLSREVQQKIDQKYDNDLETILVQWIKAQCGTHAGSFDGQGKSAVQVWLKDGTVLSHLINSLAPGSIAKV-QTSAMAFKQMEQISQFLKACERYGIPASDLFQTVDLWEGKDMASVQRTLMNLGGIAVTKGDGYFRGDPNWFPKKSQENKREFSQDKLKEGQNIIGLQMGTNKGASQSGMTGYGMPRQI 196

[Close]

BLAST of Transgelin vs. Ensembl Xenopus
Match: slc5a8.1 (solute carrier family 5 member 8, gene 1 [Source:Xenbase;Acc:XB-GENE-479634])

HSP 1 Score: 145.206 bits (365), Expect = 6.006e-41
Identity = 82/191 (42.93%), Postives = 119/191 (62.30%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPI--LGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +E E  +WIE + G  +   K + D+L+ G++LC+++NKLQPG ++KINE +T  +  +ENI  F + I +YGV   D+F+  DL+E  ++ QV  TL AL    +      G    +G K A   +R +  + +K G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    6 NKGPAYGLSAEVKNKLAQKYDVQKEAELREWIEGLTGRTI--GKGFMDSLKDGIILCELINKLQPGTVRKINE-ATQNWHKLENIGNFIKGITQYGVKPHDIFEANDLFENTNLTQVQYTLLALASVAKT----KGATVDIGVKYADRQERKYDLDKLKEGRNIIGLQMGTNKYASQKGMTSYGTRRHLYD 189

[Close]

BLAST of Transgelin vs. Ensembl Xenopus
Match: tfdp1 (transcription factor Dp-1 [Source:Xenbase;Acc:XB-GENE-1219073])

HSP 1 Score: 143.28 bits (360), Expect = 6.288e-40
Identity = 79/189 (41.80%), Postives = 121/189 (64.02%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK K+ +K DP  E+E   WIE + G  +   ++++  LR G++LC ++NKLQPG IKKINE + + +  +ENI  F +A++ YG+   D+F+  DL+E  ++ QV  +L +L    +    +    +G K A + KR F  E +K G ++IGLQMGTN+ ASQ+GMT +G +R + D
Sbjct:    5 NKGPAYGLSAEVKNKIAQKYDPQVEEELRLWIEEVTGMII--GENFQQGLRDGIILCNLINKLQPGSIKKINE-AKLNWHKLENIGNFIKAMQDYGMKPHDIFEANDLFENGNMTQVQTSLVSLAGLAKTRGFHTSVDIGVKYAEKQKRQFGDEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. Ensembl Xenopus
Match: kcnb2 (potassium channel, voltage gated Shab related subfamily B, member 2 [Source:Xenbase;Acc:XB-GENE-989392])

HSP 1 Score: 136.346 bits (342), Expect = 1.040e-38
Identity = 83/199 (41.71%), Postives = 122/199 (61.31%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSK----SYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGR--TCQVHPEYNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YG+S +V+ ++ +K D   EQ  + WI    G+ + + +     ++  L++G++L K++N L P     +K  +   +M FK ME +  F  A + YGV  TD+FQTVDLYE KD+A V +T+ ALG     +   +Y G P    K A E+KR F+ E +K G NIIGLQMG+NQGA+QSGMT +G+ R I
Sbjct:    1 MANKGPSYGMSREVQSRIEKKYDEELEQRLVQWICIQCGDDVGTPEQGRLGFQQWLKNGLVLSKLINSLYPKGSQPVKIPDPPPSMVFKQMEQVAQFLRASEDYGVVKTDMFQTVDLYEGKDMAAVQRTIVALGSIAVTKNDGQYKGDPSWFMKKAQEHKRDFSDEKLKEGKNIIGLQMGSNQGATQSGMTGYGRPRQI 199

[Close]

BLAST of Transgelin vs. Ensembl Xenopus
Match: kcnb2 (potassium channel, voltage gated Shab related subfamily B, member 2 [Source:Xenbase;Acc:XB-GENE-989392])

HSP 1 Score: 136.732 bits (343), Expect = 1.167e-38
Identity = 83/199 (41.71%), Postives = 121/199 (60.80%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSK----SYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQV--HPEYNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YG+S +V+ ++ +K D   EQ  + WI    G+ + + +     ++  L++G++L K++N L P     +K  +   +M FK ME +  F  A + YGV  TD+FQTVDLYE KD+A V +T+ ALG         +Y G P    K A E+KR F+ E +K G NIIGLQMG+NQGA+QSGMT +G+ R I
Sbjct:    7 MANKGPSYGMSREVQSRIEKKYDEELEQRLVQWICIQCGDDVGTPEQGRLGFQQWLKNGLVLSKLINSLYPKGSQPVKIPDPPPSMVFKQMEQVAQFLRASEDYGVVKTDMFQTVDLYEGKDMAAVQRTIVALGSIAVTKNDGQYKGDPSWFMKKAQEHKRDFSDEKLKEGKNIIGLQMGSNQGATQSGMTGYGRPRQI 205

[Close]

BLAST of Transgelin vs. Ensembl Mouse
Match: Cnn1 (calponin 1 [Source:MGI Symbol;Acc:MGI:104979])

HSP 1 Score: 152.91 bits (385), Expect = 9.461e-45
Identity = 86/189 (45.50%), Postives = 122/189 (64.55%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +EQE  +WIE + G ++ +  ++ D L+ G++LC+ +NKLQPG +KK+NE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F  E ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGN--NFMDGLKDGIILCEFINKLQPGSVKKVNE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. Ensembl Mouse
Match: Cnn1 (calponin 1 [Source:MGI Symbol;Acc:MGI:104979])

HSP 1 Score: 153.295 bits (386), Expect = 4.175e-44
Identity = 86/189 (45.50%), Postives = 122/189 (64.55%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +EQE  +WIE + G ++ +  ++ D L+ G++LC+ +NKLQPG +KK+NE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F  E ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGN--NFMDGLKDGIILCEFINKLQPGSVKKVNE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. Ensembl Mouse
Match: Tagln3 (transgelin 3 [Source:MGI Symbol;Acc:MGI:1926784])

HSP 1 Score: 148.673 bits (374), Expect = 1.368e-43
Identity = 87/199 (43.72%), Postives = 126/199 (63.32%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSS----KSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K D + E + +DWI     E ++        ++  L  G +LCK++N L P     I KI+E S M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A +N+RGF++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISE-SKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQI 198

[Close]

BLAST of Transgelin vs. Ensembl Mouse
Match: Tagln2 (transgelin 2 [Source:MGI Symbol;Acc:MGI:1312985])

HSP 1 Score: 140.198 bits (352), Expect = 2.705e-40
Identity = 83/199 (41.71%), Postives = 126/199 (63.32%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEA----ILGEKLDSSKSYEDNLRSGVLLCKVMNKLQP---GIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ ++ D + EQ  I WI       +G+     ++++  L+ G +LCK++N L P     +KKI + S+M FK ME I+ F +A ++YG+  TD+FQTVDL+E K++A V +TL  LG       +  ++G P   PK + EN R F+   ++ G N+IGLQMGTN+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKI-QASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQI 198

[Close]

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEA----ILGEKLDSSKSYEDNLRSGVLLCKVMNKLQP---GIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ ++ D + EQ  I WI       +G+     ++++  L+ G +LCK++N L P     +KKI + S+M FK ME I+ F +A ++YG+  TD+FQTVDL+E K++A V +TL  LG       +  ++G P   PK + EN R F+   ++ G N+IGLQMGTN+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVQQKIEKQYDADLEQILIQWITTQCREDVGQPQPGRENFQKWLKDGTVLCKLINSLYPEGQAPVKKI-QASSMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQI 198

[Close]

BLAST of Transgelin vs. UniProt/SwissProt
Match: sp|Q24799|MYPH_ECHGR (Myophilin OS=Echinococcus granulosus OX=6210 PE=2 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 1.971e-92
Identity = 128/190 (67.37%), Postives = 157/190 (82.63%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            M+N     GLS QVKKKL  KRD +QE EA++WIEA+ G KLD SK YED L+ G +LCK+MN ++PG IKKINEN+TMPFKIMENI+AF EA+K YGVP+ D+FQTVDL+EKKDIAQVT+TLFALGRTCQ HPEY+GP+LGPKLA ENKR FT++ ++ G N++ LQ G+N+GASQ+G+  GKQRMI D
Sbjct:    1 MSNVPPPSGLSYQVKKKLEGKRDKDQENEALEWIEALTGLKLDRSKLYEDILKDGTVLCKLMNSIKPGCIKKINENATMPFKIMENISAFLEAMKGYGVPVADLFQTVDLFEKKDIAQVTRTLFALGRTCQTHPEYSGPVLGPKLATENKREFTEQQLREGQNVVSLQYGSNKGASQAGINMGKQRMIMD 190

[Close]

BLAST of Transgelin vs. UniProt/SwissProt
Match: sp|P14318|MP20_DROME (Muscle-specific protein 20 OS=Drosophila melanogaster OX=7227 GN=Mp20 PE=2 SV=2)

HSP 1 Score: 197.978 bits (502), Expect = 3.585e-62
Identity = 97/179 (54.19%), Postives = 126/179 (70.39%), Query Frame = 2

Query:   92 LSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            L   V+ K+  KR+P  ++EA +WIEAI+ EK  + +SYED L+ G +LCK++N L P  + K+N +S   FK MENIN FQ+A+K+YGVP  DVFQTVDLYEKKDIA VT T+FALGR    H ++ GP LGPK A E KR FT+E +K G  I+GLQ G+N+GA+Q+G   G  R I
Sbjct:    3 LERAVRAKIASKRNPEMDKEAQEWIEAIIAEKFPAGQSYEDVLKDGQVLCKLINVLSPNAVPKVN-SSGGQFKFMENINNFQKALKEYGVPDIDVFQTVDLYEKKDIANVTNTIFALGRATYKHADFKGPFLGPKPADECKRDFTEEQLKAGQTIVGLQAGSNKGATQAGQNLGAGRKI 180

[Close]

BLAST of Transgelin vs. UniProt/SwissProt
Match: sp|Q9GK38|CNN1_MUSPF (Calponin-1 OS=Mustela putorius furo OX=9669 GN=CNN1 PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 6.300e-44
Identity = 87/189 (46.03%), Postives = 122/189 (64.55%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +EQE  +WIE + G ++ S  ++ D L+ G++LC+ +NKLQPG +KK+NE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F  E ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGS--NFMDGLKDGIILCEFINKLQPGSVKKVNE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERKFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. UniProt/SwissProt
Match: sp|Q08290|CNN1_RAT (Calponin-1 OS=Rattus norvegicus OX=10116 GN=Cnn1 PE=1 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 7.470e-44
Identity = 87/189 (46.03%), Postives = 122/189 (64.55%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  +EQE  +WIE + G ++ S  ++ D L+ G++LC+ +NKLQPG +KK+NE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F  E ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGS--NFMDGLKDGIILCEFINKLQPGSVKKVNE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. UniProt/SwissProt
Match: sp|Q08092|CNN1_PIG (Calponin-1 OS=Sus scrofa OX=9823 GN=CNN1 PE=2 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 7.796e-44
Identity = 87/189 (46.03%), Postives = 122/189 (64.55%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND 634
            N+G AYGLSA+VK KL +K D  QEQE  +WIE + G ++ +  ++ D L+ G++LC+ +NKLQPG +KK+NE ST  +  +ENI  F +AI KYGV   D+F+  DL+E  +  QV  TL AL    +   + N   +G K A + +R F  E ++ G NIIGLQMGTN+ ASQ GMT +G +R + D
Sbjct:    7 NRGPAYGLSAEVKNKLAQKYDHQQEQELREWIEGVTGRRIGN--NFMDGLKDGIILCEFINKLQPGSVKKVNE-STQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMAKT--KGNKVNVGVKYAEKQERKFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHLYD 190

[Close]

BLAST of Transgelin vs. TrEMBL
Match: Q6IV29 (Transgelin OS=Echinococcus granulosus OX=6210 PE=3 SV=1)

HSP 1 Score: 301.212 bits (770), Expect = 3.314e-100
Identity = 141/190 (74.21%), Postives = 164/190 (86.32%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQ +A GLSAQVKKKL  KRD +QEQ  +DWI+A+LG K+D SK YE+ L+ GVLLCKV+NKL+PG +KKINENSTMPFKIMENINAFQEAIK YGVP +DVFQTVDL+EKKDIAQVTQ ++ALGRTCQ HPEYNGP LGPKLA ENKR F++E ++ G+N+I LQ GTN+GASQ+GMT GKQRMI D
Sbjct:    1 MANQPLASGLSAQVKKKLEGKRDRDQEQSVLDWIDAVLGTKVDRSKPYEEVLKDGVLLCKVINKLKPGSVKKINENSTMPFKIMENINAFQEAIKAYGVPTSDVFQTVDLFEKKDIAQVTQCIYALGRTCQTHPEYNGPTLGPKLAQENKREFSEEQLREGANVISLQYGTNKGASQAGMTMGKQRMILD 190

[Close]

BLAST of Transgelin vs. TrEMBL
Match: Q86DV9 (Transgelin OS=Schistosoma japonicum OX=6182 GN=EWB00_007587 PE=2 SV=1)

HSP 1 Score: 301.212 bits (770), Expect = 3.314e-100
Identity = 141/190 (74.21%), Postives = 164/190 (86.32%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQ +A GLSAQVKKKL  KRD +QEQ  +DWI+A+LG K+D SK YE+ L+ GVLLCKV+NKL+PG +KKINENSTMPFKIMENINAFQEAIK YGVP +DVFQTVDL+EKKDIAQVTQ ++ALGRTCQ HPEYNGP LGPKLA ENKR F++E ++ G+N+I LQ GTN+GASQ+GMT GKQRMI D
Sbjct:    1 MANQPLASGLSAQVKKKLEGKRDRDQEQSVLDWIDAVLGTKVDRSKPYEEVLKDGVLLCKVINKLKPGSVKKINENSTMPFKIMENINAFQEAIKAYGVPTSDVFQTVDLFEKKDIAQVTQCIYALGRTCQTHPEYNGPTLGPKLAQENKREFSEEQLREGANVISLQYGTNKGASQAGMTMGKQRMILD 190

[Close]

BLAST of Transgelin vs. TrEMBL
Match: G4M0V2 (Transgelin OS=Schistosoma mansoni OX=6183 GN=Smp_086330.1 PE=3 SV=1)

HSP 1 Score: 300.442 bits (768), Expect = 7.281e-100
Identity = 141/190 (74.21%), Postives = 162/190 (85.26%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQ +A GLSAQVK+KL  KRD +QEQ  +DWIEA+LG K+D SK YE+ L+ GVLLCKV+NKL+PG +K+INEN+TMPFKIMENINAFQEAIK YGVP  DVFQTVDL+EKKDIAQVTQ L+ALGRTCQ HPEYNGP LGPKLA ENKR FT E ++ G+N+I LQ GTN+GASQ+GMT GKQRMI D
Sbjct:    1 MANQPLASGLSAQVKRKLEGKRDRDQEQSVLDWIEAVLGTKVDRSKPYEEILKDGVLLCKVINKLKPGSVKRINENATMPFKIMENINAFQEAIKAYGVPTADVFQTVDLFEKKDIAQVTQCLYALGRTCQTHPEYNGPTLGPKLAQENKREFTDEQLREGANVISLQYGTNKGASQAGMTMGKQRMILD 190

[Close]

BLAST of Transgelin vs. TrEMBL
Match: A0A095CGN5 (Transgelin OS=Schistosoma haematobium OX=6185 GN=MS3_10736 PE=3 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 1.434e-99
Identity = 140/190 (73.68%), Postives = 162/190 (85.26%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQ +A GLSAQVK+KL  KRD +QEQ  +DWIEA+LG K+D SK YE+ L+ GVLLCKV+NKL+PG +K+INEN+TMPFKIMENINAFQEAIK YGVP  DVFQTVDL+EKKDIAQVTQ ++ALGRTCQ HPEYNGP LGPKLA ENKR FT E ++ G+N+I LQ GTN+GASQ+GMT GKQRMI D
Sbjct:    1 MANQPLASGLSAQVKRKLEGKRDRDQEQSVLDWIEAVLGTKVDCSKPYEEVLKDGVLLCKVINKLKPGSVKRINENATMPFKIMENINAFQEAIKAYGVPTADVFQTVDLFEKKDIAQVTQCIYALGRTCQTHPEYNGPTLGPKLAQENKREFTDEQLREGANVISLQYGTNKGASQAGMTMGKQRMILD 190

[Close]

BLAST of Transgelin vs. TrEMBL
Match: C1LMV1 (Transgelin OS=Schistosoma japonicum OX=6182 PE=2 SV=1)

HSP 1 Score: 299.671 bits (766), Expect = 1.617e-99
Identity = 140/190 (73.68%), Postives = 163/190 (85.79%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQ +A GLSAQVKKK   KRD +QEQ  +DWI+A+LG K+D SK YE+ L+ GVLLCKV+NKL+PG +KKINENSTMPFKIMENINAFQEAIK YGVP +DVFQTVDL+EKKDIAQVTQ ++ALGRTCQ HPEYNGP LGPKLA ENKR F++E ++ G+N+I LQ GTN+GASQ+GMT GKQRMI D
Sbjct:    1 MANQPLASGLSAQVKKKFEGKRDRDQEQSVLDWIDAVLGTKVDRSKPYEEVLKDGVLLCKVINKLKPGSVKKINENSTMPFKIMENINAFQEAIKAYGVPTSDVFQTVDLFEKKDIAQVTQCIYALGRTCQTHPEYNGPTLGPKLAQENKREFSEEQLREGANVISLQYGTNKGASQAGMTMGKQRMILD 190

[Close]

BLAST of Transgelin vs. Ensembl Cavefish
Match: TAGLN3 (transgelin 3 [Source:NCBI gene;Acc:103030448])

HSP 1 Score: 144.05 bits (362), Expect = 8.365e-42
Identity = 86/199 (43.22%), Postives = 124/199 (62.31%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD----SSKSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V +K+ +K D + E   +DWI A  G  L+      +++++ L  G +LC+++N L P     IKKI E + M FK ME I+ F  A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G      + A  N+R F++E +++G N+IGLQMG+N+GASQ+GMT +G  R I
Sbjct:    1 MANRGPSYGLSREVLEKIEQKYDTDLEVRLVDWIIAQCGGNLERPLPGKQNFQNWLMDGTILCRLINSLYPRGKEPIKKIQE-TQMAFKQMEKISQFLVAAEAYGVITTDIFQTVDLWEGKDMAAVQRTLMALGSVALTKDDGHYRGNRDWFHRTAQSNRREFSEEQLRQGQNLIGLQMGSNRGASQAGMTGYGMHRQI 198

[Close]

BLAST of Transgelin vs. Ensembl Cavefish
Match: tagln (transgelin-like [Source:NCBI gene;Acc:103045968])

HSP 1 Score: 143.665 bits (361), Expect = 1.142e-41
Identity = 84/198 (42.42%), Postives = 124/198 (62.63%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL----DSSKSYEDNLRSGVLLCKVMNKLQPG--IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS QV+ K++ K DP  E   ++WI A  G  +    +  + ++D L+ G +L +++N L      +KKI ++S M FK ME ++ F  A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  + G P    K A EN+R F+ + +K G ++IGLQMG+N+GASQ+GMT +G+ R I
Sbjct:    9 MANKGPSYGLSRQVQDKIDRKYDPELEARLVEWIVAQCGSGVAKPAEGKQGFQDWLKDGCVLSELINSLHDSDKPVKKI-QSSPMAFKQMEQVSQFLNAAEAYGVTKTDMFQTVDLWEGKDLAAVQRTLMALGSIAVTKDDGHFRGNPDWFFKKAQENRRDFSDDQLKSGKHVIGLQMGSNKGASQAGMTGYGRPRQI 205

[Close]

BLAST of Transgelin vs. Ensembl Cavefish
Match: tagln3a (transgelin-3-like [Source:NCBI gene;Acc:103024278])

HSP 1 Score: 138.658 bits (348), Expect = 1.399e-39
Identity = 84/199 (42.21%), Postives = 123/199 (61.81%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL----DSSKSYEDNLRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G +YGLS +V++K+ +K DP+ E   +DWI    G+ L       ++++  L  G +LC+++N L P     IKKI E + M FK ME I+ F EA + YGV   D+FQTVDL+E KD+A V +TL ALG       +  Y+G      + A  ++R F++E +++G  +IGLQMG+N+GASQSGM  +G  R I
Sbjct:    1 MANRGPSYGLSREVQEKIEQKYDPDLESRLVDWIMLQCGDDLVRPEPGKQNFQTWLMDGTILCRLINSLYPSGSEPIKKIPE-TKMAFKQMEKISQFLEAAEVYGVVRGDIFQTVDLWEGKDLAAVQRTLMALGSEALTKDDGHYHGNKDWFRRKAKGHRREFSEEQLRQGRALIGLQMGSNRGASQSGMVGYGTPRQI 198

[Close]

BLAST of Transgelin vs. Ensembl Cavefish
Match: cnn1b (calponin 1 [Source:NCBI gene;Acc:103040806])

HSP 1 Score: 140.969 bits (354), Expect = 1.787e-39
Identity = 81/193 (41.97%), Postives = 117/193 (60.62%), Query Frame = 2

Query:   77 GVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND*RTKME 652
            G A+GLSA+VK KL +K DP +E+E   WI  + G K+    ++ + L+ GV LC+++N LQPG ++KIN NS+  +  +ENI  F   I++YG+   D+F+  DL+E  +  QV  TL AL    +         +G K A + +R F  E +K G NIIGLQMGTN+ ASQ GMT +G +R + D +  ME
Sbjct:    9 GPAFGLSAEVKSKLAQKYDPQKEEELRLWINEVTGRKV--PDNFMEGLKDGVTLCELINALQPGTVRKIN-NSSQNWHQLENIGNFVRGIQEYGLRPHDIFEANDLFENVNHTQVQSTLIALAGMAKSKGLRTKYDIGVKYAEKQQRRFAPEKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHLYDPKVGME 198

[Close]

BLAST of Transgelin vs. Ensembl Cavefish
Match: cnn3a (calponin 3 [Source:NCBI gene;Acc:103024651])

HSP 1 Score: 139.813 bits (351), Expect = 8.009e-39
Identity = 80/195 (41.03%), Postives = 123/195 (63.08%), Query Frame = 2

Query:   71 NQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMIND*RTKME 652
            N+G AYGLSA+VK K+ +K D  +E+E   WIE + G  +    +++  L+ GV+LC+++NKLQPG IKKIN +S + +  +EN+  F +AI  YG+   D+F+  DL+E  ++ QV  TL AL    +     +   +G K A + +R F  E +K G  +IGLQMGTN+ ASQ+GMT +G +R + D +T+ +
Sbjct:    5 NKGPAYGLSAEVKSKIAQKYDLQKEEELRFWIEEVTGMPI--GDNFQKGLKDGVILCELINKLQPGAIKKIN-HSQLNWHKLENLGNFIKAILTYGLKPNDIFEANDLFENGNMTQVQTTLLALASMAKTKGMDSKVDIGVKYADKQERHFDDEKMKAGQCVIGLQMGTNKCASQAGMTAYGTRRHLYDPKTQTD 196

[Close]

BLAST of Transgelin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004017.1 (pep scaffold:Pmarinus_7.0:GL484807:925:1903:-1 gene:ENSPMAG00000003673.1 transcript:ENSPMAT00000004017.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 51.9878 bits (123), Expect = 2.400e-9
Identity = 27/81 (33.33%), Postives = 50/81 (61.73%), Query Frame = 2

Query:   92 LSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAF 334
            L A+   ++ +K D  +EQE   W+E I G  + S+  ++  L+ GV+L +++NKL+PG ++KIN +     K+M +++ F
Sbjct:    1 LCARFASQIAQKYDLQKEQELRAWMEEITGLSIGSN--FQMGLKDGVILGELINKLRPGSVRKINRSKLNWHKVMAHLSFF 79

[Close]

BLAST of Transgelin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010290.1 (pep scaffold:Pmarinus_7.0:GL476446:218476:334684:-1 gene:ENSPMAG00000009276.1 transcript:ENSPMAT00000010290.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 52.7582 bits (125), Expect = 6.352e-8
Identity = 32/109 (29.36%), Postives = 59/109 (54.13%), Query Frame = 2

Query:  146 QEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGII--KKINENST-------MPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALG 445
            +EA  W+EA + E+L  +   E++LR+GV+L K+ +   PG +  KKI +          + F+  +NIN +  A+   G+P     +T D+Y++K++ +    + AL 
Sbjct:   48 EEAKRWLEACIVEELPPTTELEESLRNGVILAKLGHFFMPGKVSLKKIYDKEQTRCKAMGLHFRHTDNINHWLSAMVAIGLPKIFYPETTDIYDRKNMPKTIYCIHALS 156

[Close]

BLAST of Transgelin vs. Ensembl Sea Lamprey
Match: iqgap2 (IQ motif containing GTPase activating protein 2 [Source:ZFIN;Acc:ZDB-GENE-030131-2878])

HSP 1 Score: 49.2914 bits (116), Expect = 5.754e-7
Identity = 41/147 (27.89%), Postives = 68/147 (46.26%), Query Frame = 2

Query:  146 QEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGII--KKINENSTMPFKIM-------ENINAFQEAIKKYGVPITDVFQTVDLYEKKD-------IAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDI 538
            +EA  W+EA L E+L  +   E+ L +GV L K+ N   P ++  +KI +     +K M       +NI  +  A++  G+P     +T D+Y++K+       I  ++  LF LG   Q+   Y             K  FT+E+I
Sbjct:   30 EEAKQWMEACLNEELPPTTELEEGLMNGVFLSKLGNFFAPEVVSLRKIYDKEQTRYKAMGLHFRHTDNIIHWLRAMEAIGLPKIFYPETTDIYDRKNMPRSIYCIHALSLYLFKLGIAPQIQDLY------------GKVNFTEEEI 164

[Close]

BLAST of Transgelin vs. Ensembl Yeast
Match: SCP1 (Component of yeast cortical actin cytoskeleton; binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin [Source:SGD;Acc:S000005894])

HSP 1 Score: 82.4185 bits (202), Expect = 2.406e-19
Identity = 53/146 (36.30%), Postives = 78/146 (53.42%), Query Frame = 2

Query:  218 LRSGVLLCKVMNKLQPGIIKKINE----NSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKR---GSNIIGLQMGTNQGASQS--GMTFGKQRMI 628
            L+ G +LCK+ N L      + N     +S MPF  M+ I+ F    +KYGVP  ++FQT+DL+EKKD A V QTL +L R          P+LGP+L+ +  R   +   K    G+     + G  +GASQ+  G+  G++R I
Sbjct:   54 LKDGTVLCKLANILYEADTGEANHISWKSSKMPFVQMDQISQFLSFSRKYGVPEDELFQTIDLFEKKDPAIVFQTLKSLSRYANKKHTDRFPVLGPQLSTKKPRPPVKSKPKHLQDGTGWSTFEYGYMKGASQATEGVVLGQRRDI 199

[Close]

BLAST of Transgelin vs. Ensembl Yeast
Match: IQG1 (Essential protein required for determination of budding pattern; promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family; relocalizes from bud neck to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000006163])

HSP 1 Score: 60.4622 bits (145), Expect = 1.029e-10
Identity = 38/97 (39.18%), Postives = 54/97 (55.67%), Query Frame = 2

Query:  161 WIEAILGEKLDSS--KSYEDNLRSGVLLCKVMNKLQPGIIKKI-NENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFAL 442
            WIEA++ E L S       D+LR+GV L K+  ++ P +   I      + FK  +NINAF   ++  GVP +  F+  DLY KK+I QV +TL  L
Sbjct:  117 WIEAVIEEALPSEIELCVGDSLRNGVFLAKLTQRINPDLTTVIFPAGDKLQFKHTQNINAFFGLVEHVGVPDSFRFELQDLYNKKNIPQVFETLHIL 213

[Close]

BLAST of Transgelin vs. Ensembl Nematostella
Match: EDO30656 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T059])

HSP 1 Score: 150.984 bits (380), Expect = 2.643e-45
Identity = 83/172 (48.26%), Postives = 115/172 (66.86%), Query Frame = 2

Query:  116 LNEKRDPNQEQEAIDWIEAILGEKLDSSKSY-EDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            ++ K DP  + EA+DWIE +LGE++   KS  ED L+ G +LC++ N L  G I+KIN NS M FK+MENI  F +    +GV  +D+FQTVDLYEK++I QV  ++ AL R        + PILGPK + +N R FT+E  + G  +IGLQMG+N+GASQ+G TFG+ R +
Sbjct:    1 MSAKYDPVMDAEAVDWIEKVLGEEVCQGKSINEDVLKDGQILCRLANHL-GGDIQKIN-NSKMAFKMMENIAKFLDFCGTFGVAKSDLFQTVDLYEKQNIQQVINSIHALARKAN-SKGLSVPILGPKESQKNPREFTEEQKRAGEGVIGLQMGSNKGASQAGDTFGRPRQV 169

[Close]

BLAST of Transgelin vs. Ensembl Nematostella
Match: EDO46712 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPC0])

HSP 1 Score: 145.206 bits (365), Expect = 7.432e-43
Identity = 85/193 (44.04%), Postives = 119/193 (61.66%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDN----LRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPI-LGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            MA++   YG++A++ +K + K D +   +A  WIE ILGE++   K+  D+    L+ G +LC+V NKL   I  KIN +S M FK+MEN   F E     GVP TD+FQTVDLYEK+++  V   + ALGR  + H      + LGPK A  N R FT+E  + G  +IGLQMG+N+GASQ+G  FG+ R +
Sbjct:    1 MASRPKGYGMTAELARKRDAKYDSDLAAQATAWIEGILGERVFGGKTGADDVHEVLKDGQVLCRVANKLGGNI--KIN-SSKMAFKMMENTGKFLEFCDTIGVPKTDMFQTVDLYEKQNMPGVINGIHALGR--KAHSTGKTCLALGPKEASANPREFTEEQRRAGQGVIGLQMGSNKGASQAGDHFGRPRQV 188

[Close]

BLAST of Transgelin vs. Ensembl Nematostella
Match: EDO44075 (Myophilin-like protein; Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWR1])

HSP 1 Score: 139.813 bits (351), Expect = 9.105e-41
Identity = 83/196 (42.35%), Postives = 114/196 (58.16%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDN----LRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQG--ASQSGMTFGKQRMIND 634
            MA++   YG+SA   +K+ EK DP QE+EA  WIEA+LGEK+       D+    L+ G +L ++  KL   I  K+NE + MPFK MENI  F       GV   D FQT DLY+  ++  V   + A+GR CQ+  + + P LGPK A  N R FT+E ++ G +I+G+Q G  Q   ASQSG  +G+ R I D
Sbjct:    1 MASRPRGYGMSAAANRKILEKYDPQQEEEARIWIEAVLGEKVFGGAEGPDDVQKVLKDGKILARLAIKLGAKI--KVNEQN-MPFKQMENIGNFLSHCGHLGVASGDQFQTADLYDNANMTSVISCIHAVGRKCQLIKDLDIPTLGPKEAEANVREFTEEQLRAGESILGMQAGPTQDQVASQSGDHYGRGRQITD 193

[Close]

BLAST of Transgelin vs. Ensembl Nematostella
Match: EDO44073 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWQ9])

HSP 1 Score: 116.316 bits (290), Expect = 5.907e-32
Identity = 73/168 (43.45%), Postives = 95/168 (56.55%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKS----YEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNI 556
            MA +   YG S + K+K+  K D  QE+E  DWIEA+LGE +   K+      D LRSGV+L +  N L   I  KIN +S M FK MENI  F    +  GV   D+FQTVDLYEK+++A V   + ALGR  +     N P LGPK A  N R F ++ ++ G  I
Sbjct:    1 MAARPKGYGFSLEAKRKIESKYDHEQEEEMRDWIEALLGESVFGGKTGIDGVHDILRSGVVLLRCANALGGNI--KIN-DSKMAFKQMENIGNFLLFCESLGVSKVDLFQTVDLYEKQNMAAVVLGVHALGRKARAKG-LNCPQLGPKEAEANPRSFDEDKLRAGKGI 164

[Close]

BLAST of Transgelin vs. Ensembl Nematostella
Match: EDO46658 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPB8])

HSP 1 Score: 114.39 bits (285), Expect = 3.636e-31
Identity = 70/175 (40.00%), Postives = 99/175 (56.57%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKL----DSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIK-KYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMG 574
            MAN+   YG SA+  KK++ K DP +E+EA  WI+ +LGE +        +    L+ G +LC++ N+L  G   KIN+   MPFK MENI  F   I+   GV   D+FQTVDLYEK ++  V   + A+GR        + P+LGPK A  N R F++E ++ G  I+  Q G
Sbjct:    1 MANKPRGYGFSAEAAKKIDSKYDPTKEEEARKWIDTVLGESIFGENGGVDTVHQTLKDGQVLCRLANRL--GGDLKINQQK-MPFKQMENIGNFLSFIENNLGVAKNDLFQTVDLYEKSNMWNVICCIHAVGRRAAAKG-LDVPVLGPKEADANPRQFSEEQLRAGEGILTKQAG 171

[Close]

BLAST of Transgelin vs. Ensembl Medaka
Match: tagln3a (transgelin 3 [Source:NCBI gene;Acc:101158980])

HSP 1 Score: 148.673 bits (374), Expect = 1.677e-43
Identity = 91/211 (43.13%), Postives = 131/211 (62.09%), Query Frame = 2

Query:   29 VFEFSLKTLLQIMANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDN----LRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNGPI-LGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            +F  S   L+  MAN+G +YGLS +V++K+ +K DP+ EQ  +DWI +  G  L+  +  ++N    L  G +LC+++N L P     IKKI E + M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G      + A   +R FT+E +++G ++IGLQMG+N+GASQSGMT +G  R I
Sbjct:    2 LFGSSAAQLIPNMANRGPSYGLSREVQEKIEQKYDPDLEQRLVDWIVSQCGGNLEKPQPGKENFQKWLMDGTILCRLINSLFPRGKEPIKKIPE-TQMAFKQMEKISQFLQAAEAYGVTTTDIFQTVDLWEGKDMAAVQRTLMALGSLAVTKDDGHYKGDRDWFHRKAQGYRREFTEEQLRQGQSLIGLQMGSNRGASQSGMTGYGMHRQI 211

[Close]

BLAST of Transgelin vs. Ensembl Medaka
Match: tagln (transgelin [Source:NCBI gene;Acc:101169057])

HSP 1 Score: 146.747 bits (369), Expect = 5.203e-43
Identity = 88/197 (44.67%), Postives = 124/197 (62.94%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSK----SYEDNLRSGVLLCKVMNKLQPG--IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            MAN+G +YG+S QV++K++ K DP  EQ  ++WI    G  +   +     ++  L+ G +L +++N L  G   +KK  ++S M FK ME I+ F  A +KYGV  TD+FQTVDL+E KD+A V +TL ALG       E  YNG P    K A ENKR F+ + +K G N+IGLQMG+N+GASQ GM++G+ R I
Sbjct:    1 MANKGPSYGMSRQVQEKIDSKYDPELEQILVEWICRQCGSGVGRPEPGKMGFQAWLKDGCILGELINSLFAGEKPVKK-TQSSPMAFKQMEQISQFLNAAEKYGVTKTDMFQTVDLWEGKDLAAVQRTLSALGSLAVTKDEGTYNGDPNWFFKKAQENKRDFSDDQLKAGKNVIGLQMGSNKGASQEGMSYGRPRQI 196

[Close]

BLAST of Transgelin vs. Ensembl Medaka
Match: tagln (transgelin [Source:NCBI gene;Acc:101169057])

HSP 1 Score: 146.747 bits (369), Expect = 6.374e-43
Identity = 88/197 (44.67%), Postives = 124/197 (62.94%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSK----SYEDNLRSGVLLCKVMNKLQPG--IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMI 628
            MAN+G +YG+S QV++K++ K DP  EQ  ++WI    G  +   +     ++  L+ G +L +++N L  G   +KK  ++S M FK ME I+ F  A +KYGV  TD+FQTVDL+E KD+A V +TL ALG       E  YNG P    K A ENKR F+ + +K G N+IGLQMG+N+GASQ GM++G+ R I
Sbjct:    8 MANKGPSYGMSRQVQEKIDSKYDPELEQILVEWICRQCGSGVGRPEPGKMGFQAWLKDGCILGELINSLFAGEKPVKK-TQSSPMAFKQMEQISQFLNAAEKYGVTKTDMFQTVDLWEGKDLAAVQRTLSALGSLAVTKDEGTYNGDPNWFFKKAQENKRDFSDDQLKAGKNVIGLQMGSNKGASQEGMSYGRPRQI 203

[Close]

BLAST of Transgelin vs. Ensembl Medaka
Match: tagln3a (transgelin 3 [Source:NCBI gene;Acc:101158980])

HSP 1 Score: 145.976 bits (367), Expect = 2.121e-42
Identity = 92/215 (42.79%), Postives = 134/215 (62.33%), Query Frame = 2

Query:   20 IQFVFEFSLKTLLQI-MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDN----LRSGVLLCKVMNKLQPG---IIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNGPI-LGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            + FV  F  +T+ +  MAN+G +YGLS +V++K+ +K DP+ EQ  +DWI +  G  L+  +  ++N    L  G +LC+++N L P     IKKI E + M FK ME I+ F +A + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G      + A   +R FT+E +++G ++IGLQMG+N+GASQSGMT +G  R I
Sbjct:    7 VLFVLCFLSQTVGRPNMANRGPSYGLSREVQEKIEQKYDPDLEQRLVDWIVSQCGGNLEKPQPGKENFQKWLMDGTILCRLINSLFPRGKEPIKKIPE-TQMAFKQMEKISQFLQAAEAYGVTTTDIFQTVDLWEGKDMAAVQRTLMALGSLAVTKDDGHYKGDRDWFHRKAQGYRREFTEEQLRQGQSLIGLQMGSNRGASQSGMTGYGMHRQI 220

[Close]

BLAST of Transgelin vs. Ensembl Medaka
Match: ENSORLT00000028673.1 (transgelin [Source:NCBI gene;Acc:101159525])

HSP 1 Score: 144.05 bits (362), Expect = 7.314e-42
Identity = 87/198 (43.94%), Postives = 124/198 (62.63%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSK----SYEDNLRSGVLLCKVMNKLQPGIIKKIN--ENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPE--YNG-PILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMT-FGKQRMI 628
            MAN+G AYGLS +V+ K+++K DP  E+  + WI A  G  +   +     ++  L+ G +LC+++N L  G  K I   +NSTM FK ME I+ F +  + YGV  TD+FQTVDL+E KD+A V +TL ALG       +  Y G P    + A EN+R F++E +  G ++IGLQMGTN+GASQ+GMT +G+ R I
Sbjct:    1 MANRGPAYGLSREVQSKIDKKYDPELEERLVQWIIAQCGSGVGQPEPDKTGFQKWLKDGCVLCELINSLY-GANKPIKTIKNSTMAFKQMEQISLFLKYAEAYGVIKTDMFQTVDLFESKDLAAVQRTLMALGSLAVTKNDGNYRGDPNWFHRKAQENRRDFSEEQLSGGKSVIGLQMGTNKGASQAGMTGYGRPRQI 197

[Close]

BLAST of Transgelin vs. Planmine SMEST
Match: SMESG000000987.1 (SMESG000000987.1)

HSP 1 Score: 390.963 bits (1003), Expect = 3.255e-139
Identity = 189/190 (99.47%), Postives = 190/190 (100.00%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 634
            MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEY+GPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND
Sbjct:    1 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYSGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND 190

[Close]

BLAST of Transgelin vs. Planmine SMEST
Match: SMESG000075026.1 (SMESG000075026.1)

HSP 1 Score: 174.481 bits (441), Expect = 5.250e-54
Identity = 82/136 (60.29%), Postives = 100/136 (73.53%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYEDNLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEY 472
            MA Q   +GLSA +KKKL EKRDP QE+E + WIE I+G  LD S  Y + L  G LLC++ N + PG IKK+N+   MPFKIMENIN F EAI +YGVP+ D+FQT+DL+EKKDI QVTQTL+ALGRT  + P Y
Sbjct:    1 MAYQPAPHGLSADIKKKLQEKRDPGQEEEVLQWIEKIIGTPLDRSIGYVNLLHGGDLLCRMFNCIVPGSIKKVNDKPIMPFKIMENINGFLEAITRYGVPVLDLFQTIDLFEKKDICQVTQTLYALGRTVIIMPYY 136

[Close]

BLAST of Transgelin vs. Planmine SMEST
Match: SMESG000057599.1 (SMESG000057599.1)

HSP 1 Score: 164.081 bits (414), Expect = 2.626e-48
Identity = 90/210 (42.86%), Postives = 129/210 (61.43%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD-SSKSYEDNLRSGVLLCKVMNKLQPGIIKK----------INENS-TMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND*RTKMELA 658
            M+N+    G+  Q+ +KLN K DP  E+E IDW+  + GE +    +S +  L++G +L K++NK+  G  KK          +  N+ + PFK MENI  F +A + YGVP   +FQTVDLYE +++AQV  TL  LG  CQ + E+ GP  GPK   ENKR FT+E ++    IIGLQ G+N+GA+Q+GM  G QR IND  + +E++
Sbjct:    1 MSNRIGDMGMDVQINRKLNSKYDPESEKEVIDWLNKVSGEHVALGMQSVQQTLKNGQILIKLINKIYEGTDKKPAAALKIRCPLKFNTMSAPFKQMENIQLFLKASEAYGVPRASLFQTVDLYESRNMAQVLNTLLQLGTECQRN-EFKGPTCGPKPTYENKREFTEEQLRSSQGIIGLQAGSNKGATQAGMRIGGQRFINDVSSGLEMS 209

[Close]

BLAST of Transgelin vs. Planmine SMEST
Match: SMESG000057599.1 (SMESG000057599.1)

HSP 1 Score: 159.844 bits (403), Expect = 2.669e-46
Identity = 90/204 (44.12%), Postives = 124/204 (60.78%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD-SSKSYEDNLRSGVLLCKVMNKLQPGIIKK----------INENS-TMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND*R 640
            M+N+    G+  Q+ +KLN K DP  E+E IDW+  + GE +    +S +  L++G +L K++NK+  G  KK          +  N+ + PFK MENI  F +A + YGVP   +FQTVDLYE +++AQV  TL  LG  CQ + E+ GP  GPK   ENKR FT+E ++    IIGLQ G+N+GASQSGM+ G  R I D R
Sbjct:    1 MSNRIGDMGMDVQINRKLNSKYDPESEKEVIDWLNKVSGEHVALGMQSVQQTLKNGQILIKLINKIYEGTDKKPAAALKIRCPLKFNTMSAPFKQMENIQLFLKASEAYGVPRASLFQTVDLYESRNMAQVLNTLLQLGTECQRN-EFKGPTCGPKPTYENKREFTEEQLRSSQGIIGLQAGSNKGASQSGMSMGAVRHIADIR 203

[Close]

BLAST of Transgelin vs. Planmine SMEST
Match: SMESG000057600.1 (SMESG000057600.1)

HSP 1 Score: 164.466 bits (415), Expect = 5.581e-46
Identity = 95/217 (43.78%), Postives = 127/217 (58.53%), Query Frame = 2

Query:   65 MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLD-SSKSYEDNLRSGVLLCKVMNKLQPGIIKK------------INENSTMPFKIMENINAFQEAIKKYGVPITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENKRGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND*RTKMELACLRKCV 676
            M+N+    G+  +V  +LN K DP  E+E IDW+  I GE +    ++ +  L++G +L K++N++  G  KK             NE    PFK MENI  F  A + YGVP T +FQTVDLYE +++ QV  TL  LG  CQ   E+ GP  GPK   ENKR FT+E ++ G  IIGLQ G+N+GASQSGM  G QR IND  T +E++   K V
Sbjct:    1 MSNRIRDMGIDVKVNGRLNSKYDPESEKEVIDWLNQITGENISFGMQNVQQALKNGQILIKLVNEIYGGTDKKPEAALKIRSPLKFNEMRA-PFKQMENIQLFLNASEAYGVPRTSLFQTVDLYESRNMVQVINTLLQLGTECQ-RNEFKGPTCGPKPTYENKREFTEEQLRSGQGIIGLQAGSNKGASQSGMRIGTQRFINDVSTGVEISDEGKSV 215

HSP 2 Score: 47.7506 bits (112), Expect = 6.203e-6
Identity = 21/38 (55.26%), Postives = 30/38 (78.95%), Query Frame = 2

Query:  545 GSNIIGLQMGTNQGASQSGMTFGKQRMIND*RTKMELA 658
            G N+IGLQ G+N+GA+Q+GM  G QR IND +T +E++
Sbjct:  569 GKNVIGLQAGSNKGATQAGMRIGTQRFINDIQTGVEMS 606

HSP 3 Score: 47.3654 bits (111), Expect = 9.598e-6
Identity = 23/44 (52.27%), Postives = 31/44 (70.45%), Query Frame = 2

Query:  545 GSNIIGLQMGTNQGASQSGMTFGKQRMIND*RTKMELACLRKCV 676
            G N+IGLQ G+N+GA+Q+GM  G QR IND  T +E++   K V
Sbjct:  410 GKNVIGLQAGSNKGATQAGMRIGTQRFINDVSTGVEISDSGKNV 453

The following BLAST results are available for this feature:

BLAST of Transgelin vs. Ensembl Human
BLAST of Transgelin vs. Ensembl Celegans
BLAST of Transgelin vs. Ensembl Fly
BLAST of Transgelin vs. Ensembl Zebrafish
BLAST of Transgelin vs. Ensembl Xenopus
BLAST of Transgelin vs. Ensembl Mouse
BLAST of Transgelin vs. UniProt/SwissProt
BLAST of Transgelin vs. TrEMBL
BLAST of Transgelin vs. Ensembl Cavefish
BLAST of Transgelin vs. Ensembl Sea Lamprey
BLAST of Transgelin vs. Ensembl Yeast
BLAST of Transgelin vs. Ensembl Nematostella
BLAST of Transgelin vs. Ensembl Medaka
BLAST of Transgelin vs. Planmine SMEST

BLAST of Transgelin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TAGLN3	1.046e-43	43.72	transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]	[more]
TAGLN3	1.046e-43	43.72	transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]	[more]
TAGLN3	1.046e-43	43.72	transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]	[more]
TAGLN3	1.046e-43	43.72	transgelin 3 [Source:HGNC Symbol;Acc:HGNC:29868]	[more]
CNN1	4.043e-43	45.50	calponin 1 [Source:HGNC Symbol;Acc:HGNC:2155]	[more]

BLAST of Transgelin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cpn-1	5.177e-35	39.67	CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EF...	[more]
cpn-1	5.177e-35	39.67	CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EF...	[more]
cpn-1	5.177e-35	39.67	CPN-1; CalPoNin [Source:UniProtKB/TrEMBL;Acc:G5EF...	[more]
cpn-2	1.636e-33	37.56	Transgelin [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU...	[more]
cpn-2	1.636e-33	37.56	Transgelin [Source:UniProtKB/TrEMBL;Acc:A0A0K3AWU...	[more]

BLAST of Transgelin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mp20	3.577e-63	54.19	gene:FBgn0002789 transcript:FBtr0087745	[more]
Mp20	4.386e-63	54.19	gene:FBgn0002789 transcript:FBtr0345532	[more]
CG5023	2.466e-56	53.80	gene:FBgn0038774 transcript:FBtr0083866	[more]
Chd64	2.559e-48	41.67	gene:FBgn0035499 transcript:FBtr0073270	[more]
Chd64	6.906e-45	43.50	gene:FBgn0035499 transcript:FBtr0310531	[more]

BLAST of Transgelin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tagln2	4.446e-44	42.50	transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]	[more]
tagln2	4.446e-44	42.50	transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]	[more]
tagln2	9.365e-44	42.50	transgelin 2 [Source:ZFIN;Acc:ZDB-GENE-020802-2]	[more]
tagln	7.289e-43	43.65	transgelin [Source:ZFIN;Acc:ZDB-GENE-070912-1]	[more]
tagln	7.289e-43	43.65	transgelin [Source:ZFIN;Acc:ZDB-GENE-070912-1]	[more]

BLAST of Transgelin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tagln2	3.197e-45	45.18	transgelin 2 [Source:NCBI gene;Acc:394981]	[more]
slc5a8.1	6.006e-41	42.93	solute carrier family 5 member 8, gene 1 [Source:X...	[more]
tfdp1	6.288e-40	41.80	transcription factor Dp-1 [Source:Xenbase;Acc:XB-G...	[more]
kcnb2	1.040e-38	41.71	potassium channel, voltage gated Shab related subf...	[more]
kcnb2	1.167e-38	41.71	potassium channel, voltage gated Shab related subf...	[more]

BLAST of Transgelin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cnn1	9.461e-45	45.50	calponin 1 [Source:MGI Symbol;Acc:MGI:104979]	[more]
Cnn1	4.175e-44	45.50	calponin 1 [Source:MGI Symbol;Acc:MGI:104979]	[more]
Tagln3	1.368e-43	43.72	transgelin 3 [Source:MGI Symbol;Acc:MGI:1926784]	[more]
Tagln2	2.705e-40	41.71	transgelin 2 [Source:MGI Symbol;Acc:MGI:1312985]	[more]
Tagln2	2.705e-40	41.71	transgelin 2 [Source:MGI Symbol;Acc:MGI:1312985]	[more]

BLAST of Transgelin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q24799\|MYPH_ECHGR	1.971e-92	67.37	Myophilin OS=Echinococcus granulosus OX=6210 PE=2 ...	[more]
sp\|P14318\|MP20_DROME	3.585e-62	54.19	Muscle-specific protein 20 OS=Drosophila melanogas...	[more]
sp\|Q9GK38\|CNN1_MUSPF	6.300e-44	46.03	Calponin-1 OS=Mustela putorius furo OX=9669 GN=CNN...	[more]
sp\|Q08290\|CNN1_RAT	7.470e-44	46.03	Calponin-1 OS=Rattus norvegicus OX=10116 GN=Cnn1 P...	[more]
sp\|Q08092\|CNN1_PIG	7.796e-44	46.03	Calponin-1 OS=Sus scrofa OX=9823 GN=CNN1 PE=2 SV=1	[more]

BLAST of Transgelin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q6IV29	3.314e-100	74.21	Transgelin OS=Echinococcus granulosus OX=6210 PE=3...	[more]
Q86DV9	3.314e-100	74.21	Transgelin OS=Schistosoma japonicum OX=6182 GN=EWB...	[more]
G4M0V2	7.281e-100	74.21	Transgelin OS=Schistosoma mansoni OX=6183 GN=Smp_0...	[more]
A0A095CGN5	1.434e-99	73.68	Transgelin OS=Schistosoma haematobium OX=6185 GN=M...	[more]
C1LMV1	1.617e-99	73.68	Transgelin OS=Schistosoma japonicum OX=6182 PE=2 S...	[more]

BLAST of Transgelin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TAGLN3	8.365e-42	43.22	transgelin 3 [Source:NCBI gene;Acc:103030448]	[more]
tagln	1.142e-41	42.42	transgelin-like [Source:NCBI gene;Acc:103045968]	[more]
tagln3a	1.399e-39	42.21	transgelin-3-like [Source:NCBI gene;Acc:103024278]	[more]
cnn1b	1.787e-39	41.97	calponin 1 [Source:NCBI gene;Acc:103040806]	[more]
cnn3a	8.009e-39	41.03	calponin 3 [Source:NCBI gene;Acc:103024651]	[more]

BLAST of Transgelin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ENSPMAT00000004017.1	2.400e-9	33.33	pep scaffold:Pmarinus_7.0:GL484807:925:1903:-1 gen...	[more]
ENSPMAT00000010290.1	6.352e-8	29.36	pep scaffold:Pmarinus_7.0:GL476446:218476:334684:-...	[more]
iqgap2	5.754e-7	27.89	IQ motif containing GTPase activating protein 2 [S...	[more]

BLAST of Transgelin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
SCP1	2.406e-19	36.30	Component of yeast cortical actin cytoskeleton; bi...	[more]
IQG1	1.029e-10	39.18	Essential protein required for determination of bu...	[more]

BLAST of Transgelin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO30656	2.643e-45	48.26	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46712	7.432e-43	44.04	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO44075	9.105e-41	42.35	Myophilin-like protein; Predicted protein [Source...	[more]
EDO44073	5.907e-32	43.45	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46658	3.636e-31	40.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Transgelin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
tagln3a	1.677e-43	43.13	transgelin 3 [Source:NCBI gene;Acc:101158980]	[more]
tagln	5.203e-43	44.67	transgelin [Source:NCBI gene;Acc:101169057]	[more]
tagln	6.374e-43	44.67	transgelin [Source:NCBI gene;Acc:101169057]	[more]
tagln3a	2.121e-42	42.79	transgelin 3 [Source:NCBI gene;Acc:101158980]	[more]
ENSORLT00000028673.1	7.314e-42	43.94	transgelin [Source:NCBI gene;Acc:101159525]	[more]

BLAST of Transgelin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000000987.1	3.255e-139	99.47	SMESG000000987.1	[more]
SMESG000075026.1	5.250e-54	60.29	SMESG000075026.1	[more]
SMESG000057599.1	2.626e-48	42.86	SMESG000057599.1	[more]
SMESG000057599.1	2.669e-46	44.12	SMESG000057599.1	[more]
SMESG000057600.1	5.581e-46	43.78	SMESG000057600.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024775 ID=SMED30024775|Name=Transgelin|organism=Schmidtea mediterranea sexual|type=transcript|length=898bp
CTCATCCCTATAATTATTGATTCAATTTGTCTTTGAATTCAGTCTAAAAA
CTCTTTTACAGATAATGGCAAATCAAGGTGTTGCATATGGATTGAGTGCT
CAAGTAAAGAAAAAGCTGAACGAGAAACGAGATCCGAACCAGGAACAGGA
AGCCATCGACTGGATTGAAGCAATTCTCGGTGAAAAATTAGACAGTTCAA
AATCTTATGAAGATAATTTAAGAAGCGGAGTTCTCCTATGCAAAGTCATG
AATAAACTTCAACCGGGAATCATTAAGAAAATCAATGAAAACTCTACGAT
GCCATTTAAAATCATGGAAAACATTAATGCATTTCAAGAAGCGATTAAAA
AATACGGAGTTCCGATTACTGATGTGTTTCAAACCGTTGATTTGTACGAA
AAGAAAGACATTGCTCAAGTAACTCAAACTCTTTTTGCACTTGGTCGAAC
GTGCCAAGTCCATCCTGAATACAATGGACCGATTTTGGGACCTAAGCTTG
CCATGGAAAACAAGCGAGGATTCACTCAGGAAGACATAAAACGAGGATCA
AACATAATCGGCTTGCAGATGGGCACAAATCAAGGCGCATCACAAAGTGG
AATGACATTCGGCAAGCAAAGAATGATCAACGATTAAAGAACCAAAATGG
AACTCGCATGCCTCAGAAAATGTGTTTATCGTGATATATATTTAATTTTC
TGTTTAATTTTAGTTCATATTATTATTAATCTCAATATATAAATATATAT
TTATTTCCTATTATTTGTTTTAATTGATAACTGAAAATAACTTATCTTAA
TTTTCTGTCTGTATTTTTATTGTTTGATTAAAATGTCAAGGTGAATAAAT
AAGATTTGTAAACATATTTTTAGATTTTTACAAATTTCTTTTTTTCTC

protein sequence of SMED30024775-orf-1

>SMED30024775-orf-1 ID=SMED30024775-orf-1|Name=SMED30024775-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp
MANQGVAYGLSAQVKKKLNEKRDPNQEQEAIDWIEAILGEKLDSSKSYED
NLRSGVLLCKVMNKLQPGIIKKINENSTMPFKIMENINAFQEAIKKYGVP
ITDVFQTVDLYEKKDIAQVTQTLFALGRTCQVHPEYNGPILGPKLAMENK
RGFTQEDIKRGSNIIGLQMGTNQGASQSGMTFGKQRMIND*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0000428	musculature system
PLANA:0000478	pharynx musculature

Vocabulary: **INTERPRO**
Term	Definition
IPR036872	CH_dom_sf
IPR003096	SM22_calponin
IPR001715	CH-domain
IPR000557	Calponin_repeat

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003096	Smooth muscle protein/calponin	PRINTS	PR00888	SM22CALPONIN	coord: 48..63 score: 38.24 coord: 166..181 score: 80.51 coord: 153..166 score: 40.34 coord: 22..35 score: 42.86 coord: 119..133 score: 36.47 coord: 3..17 score: 61.96 coord: 98..113 score: 52.57 coord: 82..98 score: 47.4
IPR001715	Calponin homology domain	SMART	SM00033	ch_5	coord: 26..126 e-value: 9.8E-26 score: 101.5
IPR001715	Calponin homology domain	PFAM	PF00307	CH	coord: 25..131 e-value: 4.9E-23 score: 81.4
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 24..131 score: 21.353
IPR001715	Calponin homology domain	CDD	cd00014	CH	coord: 25..131 e-value: 1.54847E-28 score: 100.463
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 9..165 e-value: 1.3E-42 score: 146.9
IPR036872	CH domain superfamily	SUPERFAMILY	SSF47576	Calponin-homology domain, CH-domain	coord: 16..175
IPR000557	Calponin repeat	PFAM	PF00402	Calponin	coord: 165..188 e-value: 1.6E-12 score: 46.8
IPR000557	Calponin repeat	PROSITE	PS01052	CALPONIN_1	coord: 165..183
IPR000557	Calponin repeat	PROSITE	PS51122	CALPONIN_2	coord: 165..189 score: 11.924
None	No IPR available	PANTHER	PTHR18959:SF90	MUSCLE-SPECIFIC PROTEIN 20	coord: 11..188
None	No IPR available	PANTHER	PTHR18959	CALPONIN/TRANSGELIN	coord: 11..188