Ubiquitin carboxyl-terminal hydrolase

Overview


Name	Ubiquitin carboxyl-terminal hydrolase
Smed ID	SMED30024745
Length (bp)	1226

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Ubiquitin carboxyl-terminal hydrolase (SMED30024745) t-SNE clustered cells

Violin plots show distribution of expression levels for Ubiquitin carboxyl-terminal hydrolase (SMED30024745) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Ubiquitin carboxyl-terminal hydrolase (SMED30024745) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Ubiquitin carboxyl-terminal hydrolase (SMED30024745) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024745

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30024745	h1SMcG0005844	dd_Smed_v4_4781_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_4781_1_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30024745	h1SMcG0005844	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30024745	h1SMcG0005844	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
reproductive organ	SMED30024745	h1SMcG0005844	Contig31191	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30024745	h1SMcG0005844	Contig31191	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_4781_1_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_12110_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
dorsal region of the epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_12110_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
dorsal region of the epidermis	SMED30024745	h1SMcG0005844	dd_Smed_v4_4074_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
Match: USP21 (ubiquitin specific peptidase 21 [Source:HGNC Symbol;Acc:HGNC:12620])

HSP 1 Score: 64.3142 bits (155), Expect = 1.911e-10
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  350 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 553

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Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  350 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 553

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
Match: USP2 (ubiquitin specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:12618])

HSP 1 Score: 56.6102 bits (135), Expect = 2.928e-8
Identity = 64/234 (27.35%), Postives = 96/234 (41.03%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTN------DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIG--PKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   PKS         D     + ++ Y       + D F G L  +LTC  C +  S  F     L LP+ K     + L +C+ L F K  V ++   K  C         I + +I   PK L ++L R S   I   K TTFV          +F    T   +  Y L +V +H GT++ GHY   C    T  W+  ND+    + P S+ ++ T +A + 
Sbjct:  126 LHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGY-CSTVFDPFWDLSLPIAKRGYPEVTLMDCMRL-FTKEDV-LDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSS---VTPMSSSQVRTSDAYLL 351

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
Match: USP2 (ubiquitin specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:12618])

HSP 1 Score: 56.6102 bits (135), Expect = 3.550e-8
Identity = 64/234 (27.35%), Postives = 96/234 (41.03%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTN------DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIG--PKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   PKS         D     + ++ Y       + D F G L  +LTC  C +  S  F     L LP+ K     + L +C+ L F K  V ++   K  C         I + +I   PK L ++L R S   I   K TTFV          +F    T   +  Y L +V +H GT++ GHY   C    T  W+  ND+    + P S+ ++ T +A + 
Sbjct:  160 LHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGY-CSTVFDPFWDLSLPIAKRGYPEVTLMDCMRL-FTKEDV-LDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSS---VTPMSSSQVRTSDAYLL 385

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
Match: USP2 (ubiquitin specific peptidase 2 [Source:HGNC Symbol;Acc:HGNC:12618])

HSP 1 Score: 56.6102 bits (135), Expect = 5.661e-8
Identity = 64/235 (27.23%), Postives = 96/235 (40.85%), Query Frame = 2

Query:  413 NLLSTINDVIKNPKSGTN------DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIG--PKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
             L + +N V   PKS         D     + ++ Y       + D F G L  +LTC  C +  S  F     L LP+ K     + L +C+ L F K  V ++   K  C         I + +I   PK L ++L R S   I   K TTFV          +F    T   +  Y L +V +H GT++ GHY   C    T  W+  ND+    + P S+ ++ T +A + 
Sbjct:  368 GLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGY-CSTVFDPFWDLSLPIAKRGYPEVTLMDCMRL-FTKEDV-LDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHAV--YNLYAVSNHSGTTMGGHYTAYCRSPGTGEWHTFNDSS---VTPMSSSQVRTSDAYLL 594

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Match: Usp2 (gene:FBgn0031187 transcript:FBtr0392899)

HSP 1 Score: 62.003 bits (149), Expect = 2.263e-10
Identity = 53/213 (24.88%), Postives = 89/213 (41.78%), Query Frame = 2

Query:  413 NLLSTINDVIK----NPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-------------QYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            +L S +N  +K    N     +D   A+ T++ Y       + D F G L   L C  C    S  F     L +P+P +S   KLE CL+L   +  ++ ++   C      ++ +    I   PKYL ++L R S       +T +   S+ +E  T+   L              Y L ++ +H+G++  GHY   C +  +  W+  ND
Sbjct:   87 SLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCG-NTSVTFDPFWDLSVPLPSSSRC-KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS-------ETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFND 290

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Match: Usp2 (gene:FBgn0031187 transcript:FBtr0339506)

HSP 1 Score: 61.2326 bits (147), Expect = 7.509e-10
Identity = 53/213 (24.88%), Postives = 89/213 (41.78%), Query Frame = 2

Query:  413 NLLSTINDVIK----NPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-------------QYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            +L S +N  +K    N     +D   A+ T++ Y       + D F G L   L C  C    S  F     L +P+P +S   KLE CL+L   +  ++ ++   C      ++ +    I   PKYL ++L R S       +T +   S+ +E  T+   L              Y L ++ +H+G++  GHY   C +  +  W+  ND
Sbjct:  337 SLHSALNSGVKGETLNIDDNLSDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCG-NTSVTFDPFWDLSVPLPSSSRC-KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS-------ETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFND 540

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Match: Usp2 (gene:FBgn0031187 transcript:FBtr0077346)

HSP 1 Score: 60.4622 bits (145), Expect = 1.700e-9
Identity = 48/192 (25.00%), Postives = 81/192 (42.19%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-------------QYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            +D   A+ T++ Y       + D F G L   L C  C    S  F     L +P+P +S   KLE CL+L   +  ++ ++   C      ++ +    I   PKYL ++L R S       +T +   S+ +E  T+   L              Y L ++ +H+G++  GHY   C +  +  W+  ND
Sbjct:  649 SDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGN-TSVTFDPFWDLSVPLPSSSRC-KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS-------ETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFND 831

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Match: Usp2 (gene:FBgn0031187 transcript:FBtr0077348)

HSP 1 Score: 60.4622 bits (145), Expect = 1.700e-9
Identity = 48/192 (25.00%), Postives = 81/192 (42.19%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-------------QYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            +D   A+ T++ Y       + D F G L   L C  C    S  F     L +P+P +S   KLE CL+L   +  ++ ++   C      ++ +    I   PKYL ++L R S       +T +   S+ +E  T+   L              Y L ++ +H+G++  GHY   C +  +  W+  ND
Sbjct:  649 SDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGN-TSVTFDPFWDLSVPLPSSSRC-KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS-------ETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFND 831

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Match: Usp2 (gene:FBgn0031187 transcript:FBtr0077347)

HSP 1 Score: 60.4622 bits (145), Expect = 1.700e-9
Identity = 48/192 (25.00%), Postives = 81/192 (42.19%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-------------QYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            +D   A+ T++ Y       + D F G L   L C  C    S  F     L +P+P +S   KLE CL+L   +  ++ ++   C      ++ +    I   PKYL ++L R S       +T +   S+ +E  T+   L              Y L ++ +H+G++  GHY   C +  +  W+  ND
Sbjct:  649 SDNKKADLTWEWYTRHENSLVRDLFVGQLKSTLKCTTCGN-TSVTFDPFWDLSVPLPSSSRC-KLEACLDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRFS-------ETRWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISNHMGSTAGGHYVALCKHPVSRKWHEFND 831

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Zebrafish
Match: usp2a (ubiquitin specific peptidase 2a [Source:ZFIN;Acc:ZDB-GENE-041212-59])

HSP 1 Score: 71.633 bits (174), Expect = 3.286e-13
Identity = 60/236 (25.42%), Postives = 104/236 (44.07%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTND------KSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
            L + +N V   P+  T D      +   +K +  Y       + D F G L  +LTC +C +  S  F     L LP+ K    + L +C+ L  ++  ++ ++   C      +  +    +   PK L ++L R S   I   K +TFV          +F   +++S +  Y L +V +H GT++ GHY  +C CN E   WY  ND+    + P S  ++ + +A V   ++
Sbjct:  163 LHNEVNRVTVRPRGNTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCSECGY-CSTVFDPFWDLSLPIAKGYGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTVQKFPKILVLHLKRFSEARIRTSKLSTFVNFPMKDLDLREFASDRSSSAV--YNLYAVSNHSGTTMGGHYTAYC-CNPENGEWYTYNDSR---VTPMSASQVRSSDAYVLFYER 391

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Zebrafish
Match: usp2b (ubiquitin specific peptidase 2b [Source:ZFIN;Acc:ZDB-GENE-100208-2])

HSP 1 Score: 69.707 bits (169), Expect = 1.435e-12
Identity = 55/187 (29.41%), Postives = 87/187 (46.52%), Query Frame = 2

Query:  524 LFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTSKI-LQYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            + D F G L  +LTC +C F  S  F     L LP+ KTS  + L +CL L  ++  ++  +   C+     ++ +    I   PK L ++L R S   +   K +TFV       D  E  + + +   Y L +V +H GTS+ GHY   C    T  WY  ND+    + P S+ ++ + +A V 
Sbjct:  206 VVDLFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKTSGEVSLNDCLRLFTKEDVLDGNERPTCHRCKTRRKCTKKFTIQKFPKILVLHLKRFSECRVRTSKLSTFVNFPLKELDLREFASDNSVNAVYNLYAVSNHTGTSLGGHYTAYCRSPCTGEWYTYNDSR---VSPMSSSQVCSSDAYVL 388

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Zebrafish
Match: usp21 (ubiquitin specific peptidase 21 [Source:ZFIN;Acc:ZDB-GENE-100210-3])

HSP 1 Score: 60.8474 bits (146), Expect = 9.498e-10
Identity = 49/184 (26.63%), Postives = 80/184 (43.48%), Query Frame = 2

Query:  476 DAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSD---IIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQ------TTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT 1000
            +A   +Q + + +   + D F G L  +L C  C    SN F +   L LP+PK SD    + L  CL+L  ++ K++ E++  C   +   E +    I   P+ L ++L+R ++      K+T         +            + Y L +V +H GT   GHY   C  E E W   ND+
Sbjct:  193 EAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCSHY-SNTFDVFCDLSLPIPKKSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTIQRFPRVLVIHLNRFAMSRFSISKSTVPVSFPLTALDLGLFGPVDCGPVLYDLYAVCNHSGTVNMGHYTAACR-EEEGWCFYNDS 374

[Close]

Query:  476 DAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSD---IIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQ------TTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT 1000
            +A   +Q + + +   + D F G L  +L C  C    SN F +   L LP+PK SD    + L  CL+L  ++ K++ E++  C   +   E +    I   P+ L ++L+R ++      K+T         +            + Y L +V +H GT   GHY   C  E E W   ND+
Sbjct:  193 EAFAMWQRHLDRDDSKIVDLFSGQLRSSLHCSVCSHY-SNTFDVFCDLSLPIPKKSDYGRAVTLRECLDLFSQEEKLDKENSPMCERCNRRTESTKRLTIQRFPRVLVIHLNRFAMSRFSISKSTVPVSFPLTALDLGLFGPVDCGPVLYDLYAVCNHSGTVNMGHYTAACR-EEEGWCFYNDS 374

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Match: med4 (mediator complex subunit 4 [Source:Xenbase;Acc:XB-GENE-972352])

HSP 1 Score: 55.4546 bits (132), Expect = 7.671e-8
Identity = 60/230 (26.09%), Postives = 100/230 (43.48%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTND---KSDAEK---TYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSL-MIDGEKKTTFVTCS----DFIEIQTTSKI-LQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   P+  + D     D+EK    ++ Y       + + F G L  +LTC +C +  S  F     L LP+ K S   + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S   I   K +TFV       D  E  + S     Y L +V +H GT++ GHY   C N     WY  ND+    +   S++++ + +A V 
Sbjct:  115 LHNEVNRVTVKPRPSSQDLDHMPDSEKGKHMWKRYLEREDSRIVELFVGQLKSSLTCTECGY-CSTVFDPFWDLSLPIAKKSASEVSLVDCMRLFTKEDVLDGDEKPTCCRCKARRRCTKKFTIQKFPKILVLHLKRFSEGRIRSGKLSTFVNFPLKDLDLREFSSESNPHATYNLYAVSNHSGTTMGGHYTAYCKNPSNGEWYTFNDSRVTAM---SSNQVRSSDAYVL 340

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Match: med4 (mediator complex subunit 4 [Source:Xenbase;Acc:XB-GENE-972352])

HSP 1 Score: 55.0694 bits (131), Expect = 1.003e-7
Identity = 60/230 (26.09%), Postives = 100/230 (43.48%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTND---KSDAEK---TYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSL-MIDGEKKTTFVTCS----DFIEIQTTSKI-LQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   P+  + D     D+EK    ++ Y       + + F G L  +LTC +C +  S  F     L LP+ K S   + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S   I   K +TFV       D  E  + S     Y L +V +H GT++ GHY   C N     WY  ND+    +   S++++ + +A V 
Sbjct:  117 LHNEVNRVTVKPRPSSQDLDHMPDSEKGKHMWKRYLEREDSRIVELFVGQLKSSLTCTECGY-CSTVFDPFWDLSLPIAKKSASEVSLVDCMRLFTKEDVLDGDEKPTCCRCKARRRCTKKFTIQKFPKILVLHLKRFSEGRIRSGKLSTFVNFPLKDLDLREFSSESNPHATYNLYAVSNHSGTTMGGHYTAYCKNPSNGEWYTFNDSRVTAM---SSNQVRSSDAYVL 342

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Match: med4 (mediator complex subunit 4 [Source:Xenbase;Acc:XB-GENE-972352])

HSP 1 Score: 55.0694 bits (131), Expect = 1.432e-7
Identity = 60/230 (26.09%), Postives = 100/230 (43.48%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTND---KSDAEK---TYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSL-MIDGEKKTTFVTCS----DFIEIQTTSKI-LQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   P+  + D     D+EK    ++ Y       + + F G L  +LTC +C +  S  F     L LP+ K S   + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S   I   K +TFV       D  E  + S     Y L +V +H GT++ GHY   C N     WY  ND+    +   S++++ + +A V 
Sbjct:  328 LHNEVNRVTVKPRPSSQDLDHMPDSEKGKHMWKRYLEREDSRIVELFVGQLKSSLTCTECGY-CSTVFDPFWDLSLPIAKKSASEVSLVDCMRLFTKEDVLDGDEKPTCCRCKARRRCTKKFTIQKFPKILVLHLKRFSEGRIRSGKLSTFVNFPLKDLDLREFSSESNPHATYNLYAVSNHSGTTMGGHYTAYCKNPSNGEWYTFNDSRVTAM---SSNQVRSSDAYVL 553

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Match: klkb1 (kallikrein B1 [Source:Xenbase;Acc:XB-GENE-985051])

HSP 1 Score: 50.8322 bits (120), Expect = 1.940e-6
Identity = 45/194 (23.20%), Postives = 82/194 (42.27%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKK-----------TTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT 1000
            +D   A + ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++  E+A  C+ C   T+    +  I   P+ L ++L+R S      KK              +  +  + +   +    Y L ++ +H G+   GHY   C  ++ +WY  ND+
Sbjct:  110 SDDERANQMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSPTFEVFCDLSLPIPKKGFAGGRVSLLDCFSLFTKEEELNSENAPICDRCRQRTRSTKKLT-IQRFPRILVLHLNRFSTTRFSIKKCSVSVDFPLLPAGLLPVTSLVPLIFCTGNPTYNLYALCNHSGSVHYGHYTAYCRTQS-SWYAYNDS 300

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Match: klkb1 (kallikrein B1 [Source:Xenbase;Acc:XB-GENE-985051])

HSP 1 Score: 49.2914 bits (116), Expect = 8.076e-6
Identity = 45/194 (23.20%), Postives = 82/194 (42.27%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKK-----------TTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT 1000
            +D   A + ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++  E+A  C+ C   T+    +  I   P+ L ++L+R S      KK              +  +  + +   +    Y L ++ +H G+   GHY   C  ++ +WY  ND+
Sbjct:  289 SDDERANQMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSPTFEVFCDLSLPIPKKGFAGGRVSLLDCFSLFTKEEELNSENAPICDRCRQRTRSTKKLT-IQRFPRILVLHLNRFSTTRFSIKKCSVSVDFPLLPAGLLPVTSLVPLIFCTGNPTYNLYALCNHSGSVHYGHYTAYCRTQS-SWYAYNDS 479

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
Match: Usp21 (ubiquitin specific peptidase 21 [Source:MGI Symbol;Acc:MGI:1353665])

HSP 1 Score: 64.3142 bits (155), Expect = 1.110e-10
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  351 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 554

[Close]

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  351 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 554

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
Match: Usp21 (ubiquitin specific peptidase 21 [Source:MGI Symbol;Acc:MGI:1353665])

HSP 1 Score: 64.3142 bits (155), Expect = 1.175e-10
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  354 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 557

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
Match: Usp50 (ubiquitin specific peptidase 50 [Source:MGI Symbol;Acc:MGI:1922333])

HSP 1 Score: 57.7658 bits (138), Expect = 7.597e-9
Identity = 49/217 (22.58%), Postives = 98/217 (45.16%), Query Frame = 2

Query:  383 SGDDVNKCFMNLLSTINDVIKNP-KSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDR--------GSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDT 1000
            +  D  +  + +L+ +++ +K   +   N+K   +   +         +   F G LS+++TC KC+   +++ ++   L LP+P   +   L++CL+  F++  +   + + C+  +  +E ++   I+  PK +  +  R          L  D     T +  + +I      K   Y L +V++H G    GHY  FCK N  T+ WY  +DT
Sbjct:   67 TQQDAQEFLIYVLNELHEALKKHCRRRVNEKRTGQSCCRKVPAQETSIITRLFEGQLSYSITCLKCE-SCTHKNEVFTILSLPIPSDYEC-SLQDCLQCFFQQDTLTWSNQIYCSFCEIKQEAAVRTTISKVPKIIVFHFKRFDIQGTVKRKLRTDIHYPLTNLDLTPYI-CPVFRKHPMYNLCAVVNHFGDLDGGHYTAFCK-NSVTQAWYSFDDT 279

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
Match: Usp50 (ubiquitin specific peptidase 50 [Source:MGI Symbol;Acc:MGI:1922333])

HSP 1 Score: 57.7658 bits (138), Expect = 1.066e-8
Identity = 49/217 (22.58%), Postives = 99/217 (45.62%), Query Frame = 2

Query:  383 SGDDVNKCFMNLLSTINDVIK-NPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDR--------GSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDT 1000
            +  D  +  + +L+ +++ +K + +   N+K   +   +         +   F G LS+++TC KC+   +++ ++   L LP+P   +   L++CL+  F++  +   + + C+  +  +E ++   I+  PK +  +  R          L  D     T +  + +I      K   Y L +V++H G    GHY  FCK N  T+ WY  +DT
Sbjct:  128 TQQDAQEFLIYVLNELHEALKKHCRRRVNEKRTGQSCCRKVPAQETSIITRLFEGQLSYSITCLKCE-SCTHKNEVFTILSLPIPSDYEC-SLQDCLQCFFQQDTLTWSNQIYCSFCEIKQEAAVRTTISKVPKIIVFHFKRFDIQGTVKRKLRTDIHYPLTNLDLTPYI-CPVFRKHPMYNLCAVVNHFGDLDGGHYTAFCK-NSVTQAWYSFDDT 340

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Match: sp|O57429|UBP2_CHICK (Ubiquitin carboxyl-terminal hydrolase 2 OS=Gallus gallus OX=9031 GN=USP2 PE=2 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 3.906e-11
Identity = 74/293 (25.26%), Postives = 123/293 (41.98%), Query Frame = 2

Query:  269 EMVRNLLSDFCSLFYKLKIKRPID-----DHLNEIQQY---FISSSSGDDVNKCFMNLL-----STINDVIKNPKSGTN------DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTS-KILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
             M   L+S+F  L   L    P D     +   +IQ+Y   F+  +  D     F+  L       +N V+  P++  +      D   + + ++ Y+      + D F G L  +LTC +C +  S  F     L LP+PK     + L +CL L  ++  ++ ++   C         +    I   PK L ++L R S   I   K TTFV       D  E  + S     Y L +V +H GT++ GHY  +CK    +E W+  ND+    + P S+  + + +A + 
Sbjct:   61 RMRTALMSEFAKLIQLLWTSSPNDSVSPSEFKTQIQRYAPRFVGYNQQDAQE--FLRFLLDGLHGEVNRVLVRPRANADTLDHLPDDEKSRQMWRRYQEREDSRVSDLFVGQLKSSLTCSECGY-CSTAFDPFWDLSLPIPKKGYGEVTLMDCLRLFTKEDVLDGDEKPTCCRCKARTRCTKKFSIQKFPKILVLHLKRFSEARIRASKLTTFVNFPLKDLDLREFASQSCNHAVYNLYAVSNHSGTTMGGHYTAYCKSPISSE-WHSFNDSR---VTPMSSSHVRSSDAYLL 346

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Match: sp|Q4R6D3|UBP50_MACFA (Putative ubiquitin carboxyl-terminal hydrolase 50 OS=Macaca fascicularis OX=9541 GN=USP50 PE=2 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 6.539e-10
Identity = 47/221 (21.27%), Postives = 103/221 (46.61%), Query Frame = 2

Query:  374 SSSSGDDVNKCFMNLLSTINDVIKN---PKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTS-------KILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDT 1000
            +  +  D  +  + +L+ +++ +K    P+  +++K  A++  + +       +   F G L++++ C KC+   + + ++   L LP+P   +   L++CL+  F++  +   + + C+  +  +E ++   I+  PK +  +L R  +    ++K           +  T        K  +Y L +V++H G    GHY  FCK N  T+ WY  +DT
Sbjct:  124 TKKTQQDAQEFLIYVLNELHEALKKYHYPRRRSHEKGSAQRCCRKWITTETSVITQLFEGQLNYSIVCLKCE-KCTYKNEVFTVLSLPIPSEYEC-SLQDCLQCFFQQDTLTWNNQIHCSFCETKQETAVRAGISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICPIFRKYPKYNLCAVVNHFGDLDGGHYTAFCK-NSFTQAWYSFDDT 341

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Match: sp|Q9QZL6|UBP21_MOUSE (Ubiquitin carboxyl-terminal hydrolase 21 OS=Mus musculus OX=10090 GN=Usp21 PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 8.188e-10
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  351 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSTSRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 554

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Match: sp|Q9UK80|UBP21_HUMAN (Ubiquitin carboxyl-terminal hydrolase 21 OS=Homo sapiens OX=9606 GN=USP21 PE=1 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 9.176e-10
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  350 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 553

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Match: sp|Q2KJ72|UBP21_BOVIN (Ubiquitin carboxyl-terminal hydrolase 21 OS=Bos taurus OX=9913 GN=USP21 PE=2 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 1.155e-9
Identity = 52/212 (24.53%), Postives = 95/212 (44.81%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK---TSDIIKLENCLELLFEKSKVEIEDAMKCN-CVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTF--------VTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A   ++ Y       + D F G L   L C+ C +  S  F++   L LP+PK       + L +C  L  ++ ++E E+A  C+ C   T+    +  +   P+ L ++L+R S      KK++         ++  DF   +  S +  YQL ++ +H G+   GHY   C  +T  W++ ND+    + P S +++ +    V 
Sbjct:  350 SDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGY-RSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLT-VQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFASDKAGSPV--YQLYALCNHSGSVHYGHYTALCRCQT-GWHVYNDSR---VSPVSENQVASSEGYVL 553

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Match: A0A087UWQ5 (Ubiquitin carboxyl-terminal hydrolase (Fragment) OS=Stegodyphus mimosarum OX=407821 GN=X975_09807 PE=3 SV=1)

HSP 1 Score: 77.7962 bits (190), Expect = 9.070e-12
Identity = 73/297 (24.58%), Postives = 127/297 (42.76%), Query Frame = 2

Query:  245 NQLSYVPYEMVRNLLSDFCSLFYKLKIKRPIDDHL--NEIQQYF--ISSSSGDDVNKCFMNLLSTINDVIKNPKSGTN-------DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCK--FIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDF------IEIQTTSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
            N  S    +++R + +D     ++ K K  I+ +   +E+Q+Y    S +S  D  +    LL  ++D I   K  +N          D+ ++++ Y+ ++   + D F G L   L C  C    +  + F     + +P+P+    + L  C  L      ++  +   C         S   E++  PK L ++L R S    G+K+   V C  F      +  Q  +    Y L  V+DH G++ +GHY  KC N  T+ WY  NDT        +TD I  K  I+F +++
Sbjct:  219 NHRSPTRGDLMR-VFADVVKKVFESKTKSAINPYQLKSEVQRYAPRFSGNSQQDAQEFLRYLLQGLHDDINRIKLSSNMTIRRDSGSGDSFRSWRKYREIDDSLVVDLFAGQLKSTLKCTICNNDSVTHDPFW---DISVPIPEGGRTVSLRQCFSLFSANEYLDGANKPYCEVCKKKSRSSKKMEVSKFPKVLVIHLKRFSATCYGQKRNVMVDCPLFLGNISELAAQNCTGDGSYVLYGVVDHDGSNNSGHYTAKCQNPSTKEWYEFNDTRITK----ATDIISHKAYILFYIQE 507

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Match: A0A132A5A7 (Ubiquitin carboxyl-terminal hydrolase OS=Sarcoptes scabiei OX=52283 GN=QR98_0042870 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 2.966e-11
Identity = 58/208 (27.88%), Postives = 86/208 (41.35%), Query Frame = 2

Query:  476 DAEKTYQTYK-NMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDF------IEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETEN--WYILNDTDCRFLGPCSTDKIVTKNAIVFMLK 1072
            DA   + T+    N   +   F GL+   +TC  CK  VS   +    L LP+P+      L+NC+ L   + ++  E   +C      ++      I   P+ L ++L R     DG  +    T  DF      IE Q   K   Y L SV++H G+   GHY      + EN  W   +D D   + P     +VT+NA V   K
Sbjct:  615 DATSKFWTWHIKQNSSIVTTMFEGLIVSTVTCLHCK-SVSKSLEAFTCLTLPIPENQSRTTLKNCINLFLRRERISNEAEWQCQECKQKRDAEKCTIIWRLPQILIIHLKR--FTYDGMWRQKISTFVDFPLDNLIIEAQNGQKNQSYSLYSVVNHFGSLEGGHYVAYSRNKDENIDWNRYDDQDVSSMSPSD---VVTQNAYVLFYK 816

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Match: H0ZXR2 (USP domain-containing protein OS=Taeniopygia guttata OX=59729 PE=3 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 9.721e-11
Identity = 48/211 (22.75%), Postives = 98/211 (46.45%), Query Frame = 2

Query:  389 DDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKI-------LQYQLISVIDHIGTSVNGHYFCKCNYE-TENWYILND 997
            DD+++ F  + + + +  ++P +G + +S +  +  T+           F G LS+ + C  CK  +S+R +    L LP+P T  +  L++CLE  F+   +   + ++C+     ++ ++   I   P+ +  +L R +      +K +   C  F  +  +  I        +Y L +V++H G    GHY   C +  T++WY  +D
Sbjct:   54 DDLHEAFKEVRAQLQER-QSPAAGASTRSSSGTSIITH----------LFEGQLSYGIRCLTCK-TLSDRPESFTILSLPIPSTR-VCSLQDCLECFFQPDTLTWNNQIRCHRCGSNQDATVKASITKAPQIIIFHLKRFAWQDKHRRKLSTTVCYPFSHLDLSPYISTSCHNNTEYSLCAVVNHAGDLDYGHYTAFCKHSITKHWYSFDD 251

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Match: J7S0Y5 (Ubiquitin carboxyl-terminal hydrolase OS=Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520 / NBRC 10181 / NCYC 3082) OX=1071383 GN=KNAG0G01590 PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 1.355e-10
Identity = 57/232 (24.57%), Postives = 109/232 (46.98%), Query Frame = 2

Query:  419 LSTINDVIKNPKSGTNDKSDA-------EKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKIL-----QYQLISVIDHIGTSVNGHYFCKCNYETEN-WYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
            L  + ++ ++   G    SDA        + +  Y+  N  ++ D F G +   LTC+ C+   SN ++    L LP+P  S +  + +C++ LF+   +  +D   C+        +L   I   P+ L ++ +R   +++  KK  FV     +++   + +L      Y+L++V  H GT  +GHY   C   +EN WY  +DT C+   P S  + ++++A +   +K
Sbjct:  445 LRLLEEIHEDSNWGRPQNSDAAMQVDDYREAWNLYRKGNSSYIVDTFKGQIKSQLTCQVCQ-TQSNNYEPFSILNLPIPLVS-MCHIYDCMKELFKVHVLTGDDRWYCSTCKTKTHSTLGTTITNVPEVLIIHFNRFDNLLN--KKECFVKYPYLLDLSQGNGLLGKCDVPYKLVAVACHTGTLFSGHYTAYCFKNSENGWYHFDDTQCK---PVSNGECISQSAYLLFYQK 669

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Match: A0A3B4DGS8 (Ubiquitin specific peptidase 2b OS=Pygocentrus nattereri OX=42514 PE=3 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 1.375e-10
Identity = 58/206 (28.16%), Postives = 93/206 (45.15%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A++ +  Y       + D F G L  +LTC +C F  S  F     L LP+ K+S  + L +CL L  ++  ++  +   C      ++ +    I   PK L ++L R S   I   K  TFV+      D  E  + +    Y L +V +H GT++ GHY   C N  T  WY  ND+    + P S+ ++ + +A V 
Sbjct:  140 SDDEKAKRMWNKYLEREDSKVVDLFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPISKSSGDVSLIDCLRLFTKEDVLDGNEKPTCQRCKARRKCTKKFSIQKFPKVLVLHLKRFSEARIKTAKLCTFVSFPIKELDLREFASDNMNAIYNLYAVSNHTGTTLGGHYTAYCRNPSTGEWYTYNDSR---VSPMSSSQVRSSDAYVL 341

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Match: usp2b (ubiquitin carboxyl-terminal hydrolase 2-like [Source:NCBI gene;Acc:103044554])

HSP 1 Score: 73.559 bits (179), Expect = 5.459e-14
Identity = 57/206 (27.67%), Postives = 93/206 (45.15%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A++ +  Y       + D F G L  +LTC +C F  S  F     L LP+ K+S  + L +CL L  ++  ++  +   C      ++ +    I   PK L ++L R S   +   K +TFV       D  E  + +    Y L +V +H GT++ GHY   C N  T  WY  ND+    + P S+ ++ + +A V 
Sbjct:  165 SDDEKAKRMWNKYLEREDSKVVDLFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKSSGEVALIDCLRLFTKEDVLDGNEKPTCQRCKARRKCTKKFSIQKFPKVLVLHLKRFSEARVKTAKLSTFVNFPIKELDLREFASDNMNAIYNLYAVSNHTGTTLGGHYTAYCRNPSTGEWYTYNDSR---VSPMSSSQVRSSDAYVL 366

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Match: usp2a (ubiquitin carboxyl-terminal hydrolase 2-like [Source:NCBI gene;Acc:103025848])

HSP 1 Score: 71.633 bits (174), Expect = 2.602e-13
Identity = 60/237 (25.32%), Postives = 106/237 (44.73%), Query Frame = 2

Query:  413 NLLSTINDVIKNPKSGTND------KSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
             L + +N V   P++ T D      +   +K +  Y       + D F G L  +LTC +C +  S  F     L LP+ K    + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S   +   K +TFV          +F   +++S +  Y L +V +H GT++ GHY  +C CN  T  WY  ND+    + P S+ ++ + +A V   ++
Sbjct:  163 GLHNEVNRVTVRPRATTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCTECGY-CSTVFDPFWDLSLPIAKGYGEVSLMDCVRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTIQRFPKILVLHLKRFSEARVRSSKLSTFVNFPMKDLDLREFASDRSSSAV--YNLYAVSNHSGTTMGGHYTAYC-CNPATGEWYTYNDSR---VTPMSSSQVRSSDAYVLFYER 392

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Match: usp2b (ubiquitin carboxyl-terminal hydrolase 2-like [Source:NCBI gene;Acc:103044554])

HSP 1 Score: 71.633 bits (174), Expect = 2.709e-13
Identity = 57/207 (27.54%), Postives = 94/207 (45.41%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTSKILQ-YQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A++ +  Y       + D F G L  +LTC +C F  S  F     L LP+ K+S  + L +CL L  ++  ++  +   C      ++ +    I   PK L ++L R S   +   K +TFV       D  E  + + +   Y L +V +H GT++ GHY   C N  T  WY  ND+    + P S+ ++ + +A V 
Sbjct:  186 SDDEKAKRMWNKYLEREDSKVVDLFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKSSGEVALIDCLRLFTKEDVLDGNEKPTCQRCKARRKCTKKFSIQKFPKVLVLHLKRFSEARVKTAKLSTFVNFPIKELDLREFASDNSMNAIYNLYAVSNHTGTTLGGHYTAYCRNPSTGEWYTYNDSR---VSPMSSSQVRSSDAYVL 388

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Match: usp2b (ubiquitin carboxyl-terminal hydrolase 2-like [Source:NCBI gene;Acc:103044554])

HSP 1 Score: 71.2478 bits (173), Expect = 4.542e-13
Identity = 57/207 (27.54%), Postives = 94/207 (45.41%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVTCS----DFIEIQTTSKILQ-YQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            +D   A++ +  Y       + D F G L  +LTC +C F  S  F     L LP+ K+S  + L +CL L  ++  ++  +   C      ++ +    I   PK L ++L R S   +   K +TFV       D  E  + + +   Y L +V +H GT++ GHY   C N  T  WY  ND+    + P S+ ++ + +A V 
Sbjct:  306 SDDEKAKRMWNKYLEREDSKVVDLFVGQLKSSLTCSECGF-CSTVFDPFWDLSLPIAKSSGEVALIDCLRLFTKEDVLDGNEKPTCQRCKARRKCTKKFSIQKFPKVLVLHLKRFSEARVKTAKLSTFVNFPIKELDLREFASDNSMNAIYNLYAVSNHTGTTLGGHYTAYCRNPSTGEWYTYNDSR---VSPMSSSQVRSSDAYVL 508

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Match: usp2a (ubiquitin carboxyl-terminal hydrolase 2-like [Source:NCBI gene;Acc:103025848])

HSP 1 Score: 68.1662 bits (165), Expect = 5.583e-12
Identity = 60/238 (25.21%), Postives = 106/238 (44.54%), Query Frame = 2

Query:  413 NLLSTINDVIKNPKSGTND------KSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGS-LMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
             L + +N V   P++ T D      +   +K +  Y       + D F G L  +LTC +C +  S  F     L LP+ K     + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S   +   K +TFV          +F   +++S +  Y L +V +H GT++ GHY  +C CN  T  WY  ND+    + P S+ ++ + +A V   ++
Sbjct:  335 GLHNEVNRVTVRPRATTEDFDHLPDEEKGKKMWSKYLEREDSKIVDLFVGQLKSSLTCTECGY-CSTVFDPFWDLSLPIAKKGYGEVSLMDCVRLFTKEDVLDGDEKPTCYRCKARRRCTKKFTIQRFPKILVLHLKRFSEARVRSSKLSTFVNFPMKDLDLREFASDRSSSAV--YNLYAVSNHSGTTMGGHYTAYC-CNPATGEWYTYNDSR---VTPMSSSQVRSSDAYVLFYER 565

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008243.1 (pep scaffold:Pmarinus_7.0:GL481682:14201:19993:-1 gene:ENSPMAG00000007452.1 transcript:ENSPMAT00000008243.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.6842 bits (130), Expect = 1.643e-8
Identity = 47/196 (23.98%), Postives = 87/196 (44.39%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK-TSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKK--------TTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFC-KCNYETENWYILNDTDCRFLGP 1021
            +D   A+  +  YK++N   L   F+G     + C  C+  VS  F++  +L L +P  T+    L++CL++  +  K+   +   C+     +E     EI   P  L ++L R S     ++K         T +    +I I   ++  +Y L +V +H G+   GHY     N   ++W+  +D +  F+ P
Sbjct:  221 SDSMAAQLAWDAYKHINESILVTLFHGQFRSTIKCLTCQ-KVSRTFEVFMNLTLHLPSDTTSKCTLQDCLQMFSKPEKMTDANRYLCSHCKQRRESVKTMEIWKLPPVLIIHLKRFSYSGRWKQKLQTNVGFPLTSLDMKPYI-INKDNRYSEYNLYAVSNHYGSLDGGHYTAYTHNTVRDSWFKFDDHEVEFIYP 414

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Nematostella
Match: EDO36301 (Ubiquitin carboxyl-terminal hydrolase [Source:UniProtKB/TrEMBL;Acc:A7SIY1])

HSP 1 Score: 59.3066 bits (142), Expect = 9.844e-10
Identity = 48/196 (24.49%), Postives = 77/196 (39.29%), Query Frame = 2

Query:  440 IKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFI--------EIQTTSKILQYQLISVIDHIGTSVNGHY--FCKCNYETENWYILND 997
            +K P    +    A  T+  ++  N   + + F G+    + C  C    S  ++   +L LP+P  S+   L +C++L     ++  +D   C      +  S   +I   P  L V+L R     DG  +    T   F          I   +K   Y L  V +H GT   GHY  FCK N   + W+  +D
Sbjct:  186 LKAPDDNIDPAEAANITWDNHRKRNESLMLNLFDGMFKSTVRCLVCA-KDSVTYETFSNLTLPLPGNSNHCSLRDCIKLFTRAERMSGDDMWYCPRCKQHRVASKQLQIWRLPPILIVHLKR--FQYDGMWRQKLQTAVSFPVDGLDMSGYITGPTKRPAYHLYGVSNHYGTMHGGHYTAFCK-NAHNQRWFKFDD 377

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Nematostella
Match: EDO34837 (Ubiquitin carboxyl-terminal hydrolase [Source:UniProtKB/TrEMBL;Acc:A7SN67])

HSP 1 Score: 53.1434 bits (126), Expect = 7.814e-8
Identity = 69/339 (20.35%), Postives = 132/339 (38.94%), Query Frame = 2

Query:  161 SVYFSQLSNKIITKAILICIFINIFW*YNQLSYVPYEMVRNLLSDFCSLFYKLKIKRPIDDHLNEIQQ------YFISSSSGDDVNKCFMNLLSTINDVIKNPK-------SGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDI------------IKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVT--------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNY-ETENWYILNDTDCRFLGPCSTDKIVTKNAIVFMLKK 1075
              Y S ++NK   K  L+  F ++       S   ++   + +S      +K +I+R     +   QQ      +F+     DD+NK           V + PK       +  +D   A+K ++ Y   +   + D F G+L   L C +C F  S  F     L LP+P+ S              + + +C+EL  ++  ++ ++   C      ++ +    +   P+ L ++L R S      K  T V           +F    +  +   Y L +V +H G++  GHY   C + ++  W+  ND+    +   S+ ++    A +   +K
Sbjct:   37 GTYVSSINNKSSMKGRLVQAFADLI-----KSMWKHDATESAISAHA---FKTQIQRFAPRFVGFNQQDAQEFLHFLLEGLHDDLNK-----------VQEKPKYKMCEFDNSLSDLEKAKKAWKLYIERDNSLITDLFVGVLKSTLICLECGF-KSVTFDPFWDLSLPIPRKSGSRYSSSRYTDGGDVDIRDCMELFTKEEVLDGDERPTCEKCKKKRKSTKKFTVQRFPRILVIHLKRFSGYGFRSKLQTNVVFPVTSPQELGEFAADPSEGQSAVYSLYAVSNHSGSTYGGHYTAYCKHPQSRQWHCFNDSR---VDQISSSRVTGPQAYILFFEK 352

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
Match: usp2b (ubiquitin carboxyl-terminal hydrolase 2 [Source:NCBI gene;Acc:101165751])

HSP 1 Score: 64.6994 bits (156), Expect = 5.506e-11
Identity = 64/230 (27.83%), Postives = 99/230 (43.04%), Query Frame = 2

Query:  416 LLSTINDVIKNPKSGTND---KSDAEKT---YQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPK-TSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKK-TTFVTCS----DFIEIQT-TSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDCRFLGPCSTDKIVTKNAIVF 1063
            L + +N V   P+S   D    SD EK+   +  Y       + D F G L  +LTC  C F  S  F     L +P+ +     + L++CL L  ++  ++ E+   CN     ++ +    I   P+ L ++L R S       K +TFV       D  E     S+   Y L +V +H G ++ GHY   C N     WY  ND+    + P S+ ++ T NA V 
Sbjct:  159 LHNEVNRVTVRPRSSVEDFDHYSDEEKSKRMWNLYLAREDSKVVDLFVGQLKSSLTCTVCGF-RSTMFDPFWDLSIPIAQERPGEVTLKDCLRLFTKEDVLDGEEKPTCNKCKARRKCTKRFSIQKFPQILVIHLKRFSDSNSRSSKLSTFVNFPLKELDLREFSADNSEHPVYNLYAVSNHTGNTLGGHYTAYCRNPALGEWYSYNDSR---VSPISSGQVRTSNAYVL 384

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
Match: usp2a (ubiquitin carboxyl-terminal hydrolase 2 [Source:NCBI gene;Acc:101158874])

HSP 1 Score: 63.1586 bits (152), Expect = 2.473e-10
Identity = 51/187 (27.27%), Postives = 81/187 (43.32%), Query Frame = 2

Query:  467 DKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTS-DIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVT-------CSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDT 1000
            D+   +K +  Y       + D F G L  +LTC  C F  S  F     L LP+ K S   + L +C+ L  ++  ++ ++   C      +  +    I   PK L ++L R S      K +TFV          +F    +T+ +  Y L +V +H GT++ GHY   C N  +  WY  ND+
Sbjct:  383 DEEKGKKMWSKYVEREDSKIVDLFVGQLKSSLTCSHCGF-CSTVFDPFWDLSLPISKKSYGEVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRRCTKKFRIQKFPKILVLHLKRFSEARRTSKLSTFVNFPLKDLDLREFASGNSTNAM--YNLYAVSNHSGTTMGGHYTAYCRNPNSGEWYTFNDS 566

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
Match: ENSORLT00000003855.2 (ubiquitin specific peptidase 50 [Source:NCBI gene;Acc:105356684])

HSP 1 Score: 51.9878 bits (123), Expect = 7.843e-7
Identity = 43/165 (26.06%), Postives = 71/165 (43.03%), Query Frame = 2

Query:  536 FYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDR-GSLMIDGEKKTTFVTCSDFIEIQTTSKIL--------QYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDT 1000
            F G LS+   C  C     N  Q    L LPVPK +    +++CL L F+++ +   +   C+     +E +++  +   P+ L ++L R GS    G+ +    T   F      S+ L         Y L +V++H G    GHY   C N   + W+  +D 
Sbjct:  552 FEGQLSYMCICMHCHHQAHNT-QAFTVLSLPVPKGNIKCSIQDCLALFFKQTVLTGGEQAMCSVCGLKRETAIVTCVDRTPEILVLHLKRFGS---KGKSQVKLRTNVLFFMKLDLSQFLSGLVPNESSYHLYAVVNHTGHLNMGHYTALCYNSLAQTWHCFDDA 712

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
Match: usp8 (ubiquitin specific peptidase 8 [Source:NCBI gene;Acc:101172642])

HSP 1 Score: 50.447 bits (119), Expect = 2.583e-6
Identity = 48/191 (25.13%), Postives = 77/191 (40.31%), Query Frame = 2

Query:  464 NDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFI---------EIQTTSKILQYQLISVIDHIGTSVNGHYFCKC-NYETENWYILNDTDC 1006
            +D++ A+  +  +K +N   +   F G     + C  C    S  F+    L LP+  TS    L++CL L  ++ K+   + + C      ++ +   EI   P  L V+L R S   +G  K    T  DF           I     + +Y L  V +H G    GHY   C N   + WY  +D + 
Sbjct:  871 DDQTAADLAWSKHKLLNESIIVALFQGQFKSTVQCSTC-HRKSRTFETFMYLSLPLASTSKC-SLQDCLRLFSKEEKLTDNNKVFCRHCKAHRDSTKKLEIWKVPPILLVHLKRFSY--EGRWKQKLQTTVDFPLDNLDLTQYVIGPKQTLKRYYLYGVSNHYGGLDGGHYTAYCKNATKQRWYKFDDHEV 1057

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BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Match: SMESG000000765.1 (SMESG000000765.1)

HSP 1 Score: 481.485 bits (1238), Expect = 5.807e-163
Identity = 233/237 (98.31%), Postives = 235/237 (99.16%), Query Frame = 2

Query:  293 DFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTD 1003
            +FCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY  RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT+
Sbjct:  676 NFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY--RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTE 910

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Match: SMESG000000765.1 (SMESG000000765.1)

HSP 1 Score: 481.1 bits (1237), Expect = 7.322e-163
Identity = 233/237 (98.31%), Postives = 235/237 (99.16%), Query Frame = 2

Query:  293 DFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTD 1003
            +FCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY  RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT+
Sbjct:  673 NFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY--RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTE 907

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Match: SMESG000000765.1 (SMESG000000765.1)

HSP 1 Score: 481.1 bits (1237), Expect = 7.895e-163
Identity = 233/237 (98.31%), Postives = 235/237 (99.16%), Query Frame = 2

Query:  293 DFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTD 1003
            +FCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY  RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT+
Sbjct:  675 NFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY--RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTE 909

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Match: SMESG000000765.1 (SMESG000000765.1)

HSP 1 Score: 481.485 bits (1238), Expect = 8.689e-163
Identity = 233/237 (98.31%), Postives = 235/237 (99.16%), Query Frame = 2

Query:  293 DFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTD 1003
            +FCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY  RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT+
Sbjct:  675 NFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY--RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTE 909

[Close]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Match: SMESG000000765.1 (SMESG000000765.1)

HSP 1 Score: 481.1 bits (1237), Expect = 9.317e-163
Identity = 233/237 (98.31%), Postives = 235/237 (99.16%), Query Frame = 2

Query:  293 DFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTD 1003
            +FCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY  RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDT+
Sbjct:  676 NFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLLSTINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCEKCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKCNCVDGTKEVSLINEIAIGPKYLFVY--RGSLMIDGEKKTTFVTCSDFIEIQTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTE 910

The following BLAST results are available for this feature:

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Celegans
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Zebrafish
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Sea Lamprey
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Yeast
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Nematostella
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
USP21	1.911e-10	24.53	ubiquitin specific peptidase 21 [Source:HGNC Symbo...	[more]
USP21	1.911e-10	24.53	ubiquitin specific peptidase 21 [Source:HGNC Symbo...	[more]
USP2	2.928e-8	27.35	ubiquitin specific peptidase 2 [Source:HGNC Symbol...	[more]
USP2	3.550e-8	27.35	ubiquitin specific peptidase 2 [Source:HGNC Symbol...	[more]
USP2	5.661e-8	27.23	ubiquitin specific peptidase 2 [Source:HGNC Symbol...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Usp2	2.263e-10	24.88	gene:FBgn0031187 transcript:FBtr0392899	[more]
Usp2	7.509e-10	24.88	gene:FBgn0031187 transcript:FBtr0339506	[more]
Usp2	1.700e-9	25.00	gene:FBgn0031187 transcript:FBtr0077346	[more]
Usp2	1.700e-9	25.00	gene:FBgn0031187 transcript:FBtr0077348	[more]
Usp2	1.700e-9	25.00	gene:FBgn0031187 transcript:FBtr0077347	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
usp2a	3.286e-13	25.42	ubiquitin specific peptidase 2a [Source:ZFIN;Acc:Z...	[more]
usp2b	1.435e-12	29.41	ubiquitin specific peptidase 2b [Source:ZFIN;Acc:Z...	[more]
usp21	9.498e-10	26.63	ubiquitin specific peptidase 21 [Source:ZFIN;Acc:Z...	[more]
usp21	9.498e-10	26.63	ubiquitin specific peptidase 21 [Source:ZFIN;Acc:Z...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
med4	7.671e-8	26.09	mediator complex subunit 4 [Source:Xenbase;Acc:XB-...	[more]
med4	1.003e-7	26.09	mediator complex subunit 4 [Source:Xenbase;Acc:XB-...	[more]
med4	1.432e-7	26.09	mediator complex subunit 4 [Source:Xenbase;Acc:XB-...	[more]
klkb1	1.940e-6	23.20	kallikrein B1 [Source:Xenbase;Acc:XB-GENE-985051]	[more]
klkb1	8.076e-6	23.20	kallikrein B1 [Source:Xenbase;Acc:XB-GENE-985051]	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Usp21	1.110e-10	24.53	ubiquitin specific peptidase 21 [Source:MGI Symbol...	[more]
Usp21	1.110e-10	24.53	ubiquitin specific peptidase 21 [Source:MGI Symbol...	[more]
Usp21	1.175e-10	24.53	ubiquitin specific peptidase 21 [Source:MGI Symbol...	[more]
Usp50	7.597e-9	22.58	ubiquitin specific peptidase 50 [Source:MGI Symbol...	[more]
Usp50	1.066e-8	22.58	ubiquitin specific peptidase 50 [Source:MGI Symbol...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O57429\|UBP2_CHICK	3.906e-11	25.26	Ubiquitin carboxyl-terminal hydrolase 2 OS=Gallus ...	[more]
sp\|Q4R6D3\|UBP50_MACFA	6.539e-10	21.27	Putative ubiquitin carboxyl-terminal hydrolase 50 ...	[more]
sp\|Q9QZL6\|UBP21_MOUSE	8.188e-10	24.53	Ubiquitin carboxyl-terminal hydrolase 21 OS=Mus mu...	[more]
sp\|Q9UK80\|UBP21_HUMAN	9.176e-10	24.53	Ubiquitin carboxyl-terminal hydrolase 21 OS=Homo s...	[more]
sp\|Q2KJ72\|UBP21_BOVIN	1.155e-9	24.53	Ubiquitin carboxyl-terminal hydrolase 21 OS=Bos ta...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A087UWQ5	9.070e-12	24.58	Ubiquitin carboxyl-terminal hydrolase (Fragment) O...	[more]
A0A132A5A7	2.966e-11	27.88	Ubiquitin carboxyl-terminal hydrolase OS=Sarcoptes...	[more]
H0ZXR2	9.721e-11	22.75	USP domain-containing protein OS=Taeniopygia gutta...	[more]
J7S0Y5	1.355e-10	24.57	Ubiquitin carboxyl-terminal hydrolase OS=Kazachsta...	[more]
A0A3B4DGS8	1.375e-10	28.16	Ubiquitin specific peptidase 2b OS=Pygocentrus nat...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
usp2b	5.459e-14	27.67	ubiquitin carboxyl-terminal hydrolase 2-like [Sour...	[more]
usp2a	2.602e-13	25.32	ubiquitin carboxyl-terminal hydrolase 2-like [Sour...	[more]
usp2b	2.709e-13	27.54	ubiquitin carboxyl-terminal hydrolase 2-like [Sour...	[more]
usp2b	4.542e-13	27.54	ubiquitin carboxyl-terminal hydrolase 2-like [Sour...	[more]
usp2a	5.583e-12	25.21	ubiquitin carboxyl-terminal hydrolase 2-like [Sour...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000008243.1	1.643e-8	23.98	pep scaffold:Pmarinus_7.0:GL481682:14201:19993:-1 ...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO36301	9.844e-10	24.49	Ubiquitin carboxyl-terminal hydrolase [Source:Uni...	[more]
EDO34837	7.814e-8	20.35	Ubiquitin carboxyl-terminal hydrolase [Source:Uni...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
usp2b	5.506e-11	27.83	ubiquitin carboxyl-terminal hydrolase 2 [Source:NC...	[more]
usp2a	2.473e-10	27.27	ubiquitin carboxyl-terminal hydrolase 2 [Source:NC...	[more]
ENSORLT00000003855.2	7.843e-7	26.06	ubiquitin specific peptidase 50 [Source:NCBI gene;...	[more]
usp8	2.583e-6	25.13	ubiquitin specific peptidase 8 [Source:NCBI gene;A...	[more]

BLAST of Ubiquitin carboxyl-terminal hydrolase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000000765.1	5.807e-163	98.31	SMESG000000765.1	[more]
SMESG000000765.1	7.322e-163	98.31	SMESG000000765.1	[more]
SMESG000000765.1	7.895e-163	98.31	SMESG000000765.1	[more]
SMESG000000765.1	8.689e-163	98.31	SMESG000000765.1	[more]
SMESG000000765.1	9.317e-163	98.31	SMESG000000765.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024745 ID=SMED30024745|Name=Ubiquitin carboxyl-terminal hydrolase|organism=Schmidtea mediterranea sexual|type=transcript|length=1226bp
ATTTTTTCCTAGCACCGATTTTGTACTTTGGAAGAAAAAAACAATTCAAA
GCGCAGTTTCATCCAATTATGAGCAAGCTGGCAGCATACTTTTCGTGCAT
GTCCCATAGAAGGCGGTTTTCAAGTCTTCATAATAATTATAATTTGATTC
CCATTTTGATTCCGTATATTTCAGCCAGCTCTCGAATAAGATCATCACCA
AAGCCATCCTCATCTGTATTTTCATCAATATCTTTTGGTAATATAACCAA
TTAAGTTATGTACCGTATGAAATGGTTCGCAATCTCCTTAGCGATTTTTG
TAGTCTTTTTTATAAATTGAAGATCAAGCGTCCCATTGATGACCATTTAA
ATGAAATTCAGCAATATTTTATTTCCTCTTCTTCGGGTGATGATGTTAAT
AAATGCTTCATGAATTTACTCTCGACCATCAATGATGTCATAAAAAATCC
AAAATCAGGAACAAATGATAAAAGTGATGCCGAAAAAACTTATCAAACAT
ATAAAAATATGAATTATGGATTTCTTTTTGATTGTTTTTATGGACTGTTG
TCATTCGCGTTGACGTGCGAAAAATGTAAATTTATTGTCAGCAACAGATT
CCAATTGTTGAAATCTTTATGTCTTCCAGTTCCAAAAACCAGTGACATTA
TCAAATTGGAAAATTGTTTAGAATTACTCTTTGAAAAATCTAAAGTTGAA
ATTGAAGATGCTATGAAATGCAATTGTGTCGATGGAACAAAAGAGGTTTC
ATTAATTAATGAAATAGCAATCGGTCCAAAATATTTATTTGTCTATTTAG
ACCGAGGATCTCTTATGATTGATGGTGAAAAAAAAACTACCTTTGTGACA
TGTTCTGATTTCATTGAGATTCAAACTACAAGTAAAATACTTCAATACCA
ATTAATATCTGTAATAGATCATATCGGGACAAGTGTCAACGGACATTATT
TTTGTAAATGTAATTATGAAACAGAGAATTGGTATATACTAAATGACACT
GATTGTAGATTTTTGGGTCCATGTTCAACTGATAAAATTGTTACGAAAAA
TGCGATTGTTTTTATGTTGAAAAAACTTACATAAGAGTTTATGACAAAAT
CAGAATGTTTTCTGTAATGCCTTTTATGTCTGTTTCCAGATTTTACGCTT
TATTATTTCGCTTTAGGTTTAGATTTCCTATGGGAAAGATTTGGAAATTT
TTACACTTATTTTATAATAAACAGAT

protein sequence of SMED30024745-orf-1

>SMED30024745-orf-1 ID=SMED30024745-orf-1|Name=SMED30024745-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=271bp
MVRNLLSDFCSLFYKLKIKRPIDDHLNEIQQYFISSSSGDDVNKCFMNLL
STINDVIKNPKSGTNDKSDAEKTYQTYKNMNYGFLFDCFYGLLSFALTCE
KCKFIVSNRFQLLKSLCLPVPKTSDIIKLENCLELLFEKSKVEIEDAMKC
NCVDGTKEVSLINEIAIGPKYLFVYLDRGSLMIDGEKKTTFVTCSDFIEI
QTTSKILQYQLISVIDHIGTSVNGHYFCKCNYETENWYILNDTDCRFLGP
CSTDKIVTKNAIVFMLKKLT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis
GO:0016579	protein deubiquitination
GO:0006511	ubiquitin-dependent protein catabolic process

Vocabulary: **molecular function**
Term	Definition
GO:0008233	peptidase activity
GO:0008234	cysteine-type peptidase activity
GO:0036459	thiol-dependent ubiquitinyl hydrolase activity
GO:0016787	hydrolase activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0002032	epidermal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR038765	Papain-like_cys_pep_sf
IPR001394	Peptidase_C19_UCH
IPR018200	USP_CS
IPR028889	USP_dom

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	PFAM	PF00443	UCH	coord: 25..248 e-value: 6.1E-15 score: 55.4
None	No IPR available	GENE3D	G3DSA:3.90.70.10		coord: 3..269 e-value: 5.8E-26 score: 93.3
None	No IPR available	PANTHER	PTHR21646:SF23	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE USP2	coord: 49..245
None	No IPR available	PANTHER	PTHR21646	FAMILY NOT NAMED	coord: 49..245
IPR018200	Ubiquitin specific protease, conserved site	PROSITE	PS00973	USP_2	coord: 209..226
IPR028889	Ubiquitin specific protease domain	PROSITE	PS50235	USP_3	coord: 1..269 score: 21.921
IPR038765	Papain-like cysteine peptidase superfamily	SUPERFAMILY	SSF54001	Cysteine proteinases	coord: 27..256

Main menu

Ubiquitin carboxyl-terminal hydrolase

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

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