Protein lin-7 homolog

Overview


Name	Protein lin-7 homolog
Smed ID	SMED30024725
Length (bp)	722

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Protein lin-7 homolog (SMED30024725) t-SNE clustered cells

Violin plots show distribution of expression levels for Protein lin-7 homolog (SMED30024725) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Protein lin-7 homolog (SMED30024725) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Protein lin-7 homolog (SMED30024725) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30024725

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30024725	SMESG000057909.1	Contig5190	GPL15192	PMID:23079596 Forsthoefel et al., 2012
protonephridia	SMED30024725	SMESG000057909.1	dd_Smed_v4_1009_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30024725	SMESG000057909.1	dd_Smed_v4_1009_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024725	SMESG000057909.1	dd_Smed_v4_1009_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30024725	SMESG000057909.1	dd_Smed_v4_1009_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30024725	SMESG000057909.1	dd_Smed_v4_1009_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Protein lin-7 homolog vs. Ensembl Human
Match: LIN7B (lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788])

HSP 1 Score: 285.419 bits (729), Expect = 7.679e-98
Identity = 145/190 (76.32%), Postives = 173/190 (91.05%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAE+RA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

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BLAST of Protein lin-7 homolog vs. Ensembl Human
Match: LIN7C (lin-7 homolog C, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17789])

HSP 1 Score: 283.108 bits (723), Expect = 5.796e-97
Identity = 149/194 (76.80%), Postives = 174/194 (89.69%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 635
            + EP+ L+RDI RA+ELLE LQ+  ++ P+KL  LQ++LQS+FCN VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTPKVL+EME+RF+K ++ +R   T
Sbjct:    4 LGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT 197

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BLAST of Protein lin-7 homolog vs. Ensembl Human
Match: LIN7A (lin-7 homolog A, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17787])

HSP 1 Score: 261.536 bits (667), Expect = 5.432e-88
Identity = 138/193 (71.50%), Postives = 168/193 (87.05%), Query Frame = 3

Query:   45 TF*MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            T  + +PLTL RD++RA+ELLE LQ+  ++   KL  L+K+LQS+FC  +REVY++++ET+ + G  E RA ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:   16 TLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 208

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BLAST of Protein lin-7 homolog vs. Ensembl Human
Match: LIN7C (lin-7 homolog C, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17789])

HSP 1 Score: 246.128 bits (627), Expect = 7.264e-83
Identity = 121/194 (62.37%), Postives = 146/194 (75.26%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 635
            + EP+ L+RDI RA+ELLE LQ+  ++ P+KL  LQ++LQS+FCN VRE     +                          SEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTPKVL+EME+RF+K ++ +R   T
Sbjct:    4 LGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREATVAAFAA------------------------SEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT 173

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BLAST of Protein lin-7 homolog vs. Ensembl Human
Match: LIN7A (lin-7 homolog A, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17787])

HSP 1 Score: 189.889 bits (481), Expect = 1.703e-60
Identity = 102/151 (67.55%), Postives = 129/151 (85.43%), Query Frame = 3

Query:   45 TF*MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENE 497
            T  + +PLTL RD++RA+ELLE LQ+  ++   KL  L+K+LQS+FC  +REVY++++ET+ + G  E RA ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+ + ++
Sbjct:   10 TLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVLLRSQ 160

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BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Match: lin-7 (pep chromosome:WBcel235:II:14346877:14348792:-1 gene:WBGene00002996.1 transcript:Y54G11A.10a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-7)

HSP 1 Score: 234.572 bits (597), Expect = 3.936e-78
Identity = 124/183 (67.76%), Postives = 158/183 (86.34%), Query Frame = 3

Query:   69 TLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKAR 617
             L+RD+ R +EL+E +QK  ++   KL  LQ++LQS+F   VREVYE +YE++D + + E++A ATAKATVAAFAA+EGHAHPR+VE+PKT++GLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQL++VNG++VE E HEKAVDLLK+A G+VKLV+RY PK+LDEME RF++Q+ R
Sbjct:    8 NLERDVQRILELMEHVQKTGEVNNAKLASLQQVLQSEFFGAVREVYETVYESIDADTTPEIKAAATAKATVAAFAAAEGHAHPRIVELPKTDQGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLLKSAVGSVKLVIRYMPKLLDEMERRFERQRIR 190

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BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Match: lin-7 (pep chromosome:WBcel235:II:14347162:14348792:-1 gene:WBGene00002996.1 transcript:Y54G11A.10b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:lin-7)

HSP 1 Score: 229.18 bits (583), Expect = 5.834e-76
Identity = 124/183 (67.76%), Postives = 157/183 (85.79%), Query Frame = 3

Query:   69 TLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKAR 617
             L+RD+ R +EL+E +QK  ++   KL  LQ++LQS+F   VREVYE +YE++D + + E++A ATAKATVAAFAA+EGHAHPR+VE+PKT++GLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQL++VNG +VE E HEKAVDLLK+A G+VKLV+RY PK+LDEME RF++Q+ R
Sbjct:    8 NLERDVQRILELMEHVQKTGEVNNAKLASLQQVLQSEFFGAVREVYETVYESIDADTTPEIKAAATAKATVAAFAAAEGHAHPRIVELPKTDQGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNG-NVEAECHEKAVDLLKSAVGSVKLVIRYMPKLLDEMERRFERQRIR 189

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BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Match: dlg-1 (Disks large homolog 1 [Source:UniProtKB/Swiss-Prot;Acc:G5ECY0])

HSP 1 Score: 87.8113 bits (216), Expect = 1.062e-19
Identity = 44/97 (45.36%), Postives = 64/97 (65.98%), Query Frame = 3

Query:  315 PRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDK 605
            PR V++ K + GLGFN++GG E N PIYIS ++PGGVAD  G +K GD LL VNG+ + N  H++A + L+ A   V L ++Y P+     E++ +K
Sbjct:  508 PRPVQLVKGQNGLGFNIVGG-EDNEPIYISFVLPGGVADLSGNVKTGDVLLEVNGVVLRNATHKEAAEALRNAGNPVYLTLQYRPQEYQIFESKIEK 603

HSP 2 Score: 54.299 bits (129), Expect = 2.609e-8
Identity = 30/85 (35.29%), Postives = 54/85 (63.53%), Query Frame = 3

Query:  321 VVEIPKTEEGLGFNVMGGK-----EQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 560
            V+++ K   GLGF++ GG+     + ++ IY+++II  G A+  G L+ GD++L V+  S+ N  HE AV++LK     V+L+++
Sbjct:  361 VIDLVKGARGLGFSIAGGQGNEHVKGDTDIYVTKIIEEGAAELDGRLRVGDKILEVDHHSLINTTHENAVNVLKNTGNRVRLLIQ 445

HSP 3 Score: 54.299 bits (129), Expect = 2.915e-8
Identity = 29/82 (35.37%), Postives = 48/82 (58.54%), Query Frame = 3

Query:  330 IPKTEEGLGFNVMGGKEQ-----NSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 560
            + K   GLGF++ GG +Q     ++ IY++ II GG A   G +++ D + +VN  + EN  HE AV+ LK++   V L ++
Sbjct:  205 LEKGHTGLGFSITGGMDQPTEDGDTSIYVTNIIEGGAALADGRMRKNDIITAVNNTNCENVKHEVAVNALKSSGNVVSLSLK 286

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BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Match: stn-2 (SynTrophiN [Source:UniProtKB/TrEMBL;Acc:Q5WRR6])

HSP 1 Score: 65.855 bits (159), Expect = 3.020e-12
Identity = 37/88 (42.05%), Postives = 55/88 (62.50%), Query Frame = 3

Query:  306 HAHPRVVEIPKTEEGLGFNVMGGKE--QNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRY 563
            +A  +VV + K + G G ++ GG E  QN PI IS+I  G  AD  G L  GD ++ VNGIS+E + H++ V++LK++   V L VR+
Sbjct:   61 NATRQVVIVKKPDSGFGLSIKGGSENAQNMPIVISKIFKGLPADECGELFIGDAIVEVNGISIEGQSHDEVVNMLKSSGDQVTLGVRH 148

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BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Match: stn-2 (SynTrophiN [Source:UniProtKB/TrEMBL;Acc:Q5WRR6])

HSP 1 Score: 65.855 bits (159), Expect = 3.112e-12
Identity = 37/88 (42.05%), Postives = 55/88 (62.50%), Query Frame = 3

Query:  306 HAHPRVVEIPKTEEGLGFNVMGGKE--QNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRY 563
            +A  +VV + K + G G ++ GG E  QN PI IS+I  G  AD  G L  GD ++ VNGIS+E + H++ V++LK++   V L VR+
Sbjct:   61 NATRQVVIVKKPDSGFGLSIKGGSENAQNMPIVISKIFKGLPADECGELFIGDAIVEVNGISIEGQSHDEVVNMLKSSGDQVTLGVRH 148

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BLAST of Protein lin-7 homolog vs. Ensembl Fly
Match: veli (gene:FBgn0039269 transcript:FBtr0084787)

HSP 1 Score: 278.87 bits (712), Expect = 1.106e-95
Identity = 150/189 (79.37%), Postives = 166/189 (87.83%), Query Frame = 3

Query:   57 AEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            AEPLTL RD+ R++ELLE LQ   D    KL  LQK+L SDF   VREVYEH+YETVDI+GS +VRA+ATAKATVAAFAASEGHAHPRVVE+PKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE E+HEKAV+LLK A G+VKLVVRYTPKVL+EME RFDKQ+  RR
Sbjct:    5 AEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRR 193

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BLAST of Protein lin-7 homolog vs. Ensembl Fly
Match: veli (gene:FBgn0039269 transcript:FBtr0301664)

HSP 1 Score: 252.677 bits (644), Expect = 1.061e-84
Identity = 150/240 (62.50%), Postives = 166/240 (69.17%), Query Frame = 3

Query:   57 AEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEG---------------------------------------------------LGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            AEPLTL RD+ R++ELLE LQ   D    KL  LQK+L SDF   VREVYEH+YETVDI+GS +VRA+ATAKATVAAFAASEGHAHPRVVE+PKTEEG                                                   LGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE E+HEKAV+LLK A G+VKLVVRYTPKVL+EME RFDKQ+  RR
Sbjct:    5 AEPLTLSRDVKRSIELLEKLQASGDFPTTKLAALQKVLNSDFMTSVREVYEHVYETVDIQGSHDVRASATAKATVAAFAASEGHAHPRVVELPKTEEGKTRPYELRIEGIPLYHKTNTLIVKVYRPRIYVSIIHLIWKALSIFNFCFSGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLKQAVGSVKLVVRYTPKVLEEMEMRFDKQRNTRR 244

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BLAST of Protein lin-7 homolog vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0073488)

HSP 1 Score: 85.5001 bits (210), Expect = 9.088e-19
Identity = 47/102 (46.08%), Postives = 64/102 (62.75%), Query Frame = 3

Query:  315 PRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFD--KQKA 614
            PR + I K  +GLGFN++GG E    IY+S I+ GG AD    LKRGDQLLSVN +++ +  HE+A   LK + G V L+ +Y P+  +  EAR    KQ+A
Sbjct:  504 PRTITIQKGPQGLGFNIVGG-EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQA 604

HSP 2 Score: 48.521 bits (114), Expect = 2.755e-6
Identity = 37/95 (38.95%), Postives = 56/95 (58.95%), Query Frame = 3

Query:  315 PRVVEIP--KTEEGLGFNVMGG-KEQNSP----IYISRIIPGGVADRYGGLKRGDQLLSV--NGI--SVENEHHEKAVDLLKAAQGTVKLVVRYT 566
            P+V+EI   K  +GLGF++ GG   Q+ P    IY+++++ GG A   G L  GD+L++V  NG   ++EN  HE AV  LK+    V L++  T
Sbjct:  326 PKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKT 420

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BLAST of Protein lin-7 homolog vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0301288)

HSP 1 Score: 85.5001 bits (210), Expect = 1.021e-18
Identity = 47/102 (46.08%), Postives = 64/102 (62.75%), Query Frame = 3

Query:  315 PRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFD--KQKA 614
            PR + I K  +GLGFN++GG E    IY+S I+ GG AD    LKRGDQLLSVN +++ +  HE+A   LK + G V L+ +Y P+  +  EAR    KQ+A
Sbjct:  742 PRTITIQKGPQGLGFNIVGG-EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQA 842

HSP 2 Score: 48.521 bits (114), Expect = 2.425e-6
Identity = 37/95 (38.95%), Postives = 56/95 (58.95%), Query Frame = 3

Query:  315 PRVVEIP--KTEEGLGFNVMGG-KEQNSP----IYISRIIPGGVADRYGGLKRGDQLLSV--NGI--SVENEHHEKAVDLLKAAQGTVKLVVRYT 566
            P+V+EI   K  +GLGF++ GG   Q+ P    IY+++++ GG A   G L  GD+L++V  NG   ++EN  HE AV  LK+    V L++  T
Sbjct:  564 PKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKT 658

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Fly
Match: dlg1 (gene:FBgn0001624 transcript:FBtr0073490)

HSP 1 Score: 85.5001 bits (210), Expect = 1.084e-18
Identity = 47/102 (46.08%), Postives = 64/102 (62.75%), Query Frame = 3

Query:  315 PRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFD--KQKA 614
            PR + I K  +GLGFN++GG E    IY+S I+ GG AD    LKRGDQLLSVN +++ +  HE+A   LK + G V L+ +Y P+  +  EAR    KQ+A
Sbjct:  445 PRTITIQKGPQGLGFNIVGG-EDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHEEAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQA 545

HSP 2 Score: 48.521 bits (114), Expect = 2.777e-6
Identity = 37/95 (38.95%), Postives = 56/95 (58.95%), Query Frame = 3

Query:  315 PRVVEIP--KTEEGLGFNVMGG-KEQNSP----IYISRIIPGGVADRYGGLKRGDQLLSV--NGI--SVENEHHEKAVDLLKAAQGTVKLVVRYT 566
            P+V+EI   K  +GLGF++ GG   Q+ P    IY+++++ GG A   G L  GD+L++V  NG   ++EN  HE AV  LK+    V L++  T
Sbjct:  267 PKVIEIDLVKGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEKNLENVTHELAVATLKSITDKVTLIIGKT 361

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BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Match: lin7c (lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-2])

HSP 1 Score: 282.722 bits (722), Expect = 4.983e-97
Identity = 151/195 (77.44%), Postives = 176/195 (90.26%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDK-QKARRRGPNT 635
            + EP+ L+RDISRA+ELL+ LQ+  ++ P+KL  LQ++LQS+FC  VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQGTVKLVVRYTPKVL+EME+RF+K + A+RR  N 
Sbjct:    4 LGEPVRLERDISRAIELLDKLQRTGEVPPQKLQALQRVLQSEFCKAVREVYEHVYETVDINSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGTVKLVVRYTPKVLEEMESRFEKLRSAKRRQQNN 198

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BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Match: lin7c (lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-2])

HSP 1 Score: 282.337 bits (721), Expect = 9.132e-97
Identity = 150/198 (75.76%), Postives = 176/198 (88.89%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXX---XXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDK-QKARRRGPNT 635
            + EP+ L+RDISRA+ELL+ LQ+  ++ P+KL  LQ++LQS+FC  VREVYEH+YETVDI  S EVRANATA   +ATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQGTVKLVVRYTPKVL+EME+RF+K + A+RR  N 
Sbjct:    4 LGEPVRLERDISRAIELLDKLQRTGEVPPQKLQALQRVLQSEFCKAVREVYEHVYETVDINSSPEVRANATAKVSQATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGTVKLVVRYTPKVLEEMESRFEKLRSAKRRQQNN 201

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BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Match: lin7b (lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-1])

HSP 1 Score: 273.092 bits (697), Expect = 5.440e-93
Identity = 148/197 (75.13%), Postives = 170/197 (86.29%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT*Y 641
            M EPL L+RD+ R +ELL+ LQ+   L P KL  LQ++LQS FC  +REVYE +Y+T+DI G  EVRA ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG+VKLVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:   17 MTEPLCLERDVCRVIELLDRLQRSGQLPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIIGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSY 213

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665])

HSP 1 Score: 260.766 bits (665), Expect = 4.910e-88
Identity = 137/188 (72.87%), Postives = 167/188 (88.83%), Query Frame = 3

Query:   60 EPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            +PLTL+RD++RA+ELLE LQ+  D+   KL  L+K+LQS+FC  +REVY++++ET+ + G  E +A ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    7 QPLTLERDVTRAIELLEKLQESGDVPGHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEYQARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 194

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BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Match: lin7b (lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-1])

HSP 1 Score: 194.897 bits (494), Expect = 9.614e-63
Identity = 106/143 (74.13%), Postives = 122/143 (85.31%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGI 482
            M EPL L+RD+ R +ELL+ LQ+   L P KL  LQ++LQS FC  +REVYE +Y+T+DI G  EVRA ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+
Sbjct:   17 MTEPLCLERDVCRVIELLDRLQRSGQLPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIIGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGV 159

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BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Match: ENSXETT00000028683.1 (lin-7 homolog B [Source:NCBI gene;Acc:100491827])

HSP 1 Score: 280.026 bits (715), Expect = 1.056e-95
Identity = 147/190 (77.37%), Postives = 172/190 (90.53%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+ RA+ELLE LQ+  ++ P+KL  LQ++LQS FC+ VREVYE +Y+T+DI GSAE+RA+ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQGTVKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    4 LPEPLGLERDVCRAIELLERLQRSGEVPPQKLQALQRVLQSKFCSAVREVYEQLYDTLDITGSAEIRAHATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGTVKLVVRYTPKVLEEMEARFEKMRTARR 193

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BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Match: ralbp1 (ralA binding protein 1 [Source:Xenbase;Acc:XB-GENE-1016073])

HSP 1 Score: 279.641 bits (714), Expect = 1.077e-95
Identity = 149/194 (76.80%), Postives = 173/194 (89.18%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPN 632
            + EP+ L+RD+ RA+ELLE LQ+  ++ P KL  LQ++LQSDFC  VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTP+VL+EME+RF+K + A+RR  N
Sbjct:    4 VGEPIRLERDVHRAIELLEKLQRSGEVPPHKLHALQRVLQSDFCTAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPRVLEEMESRFEKMRSAKRRQQN 197

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Match: lin7a (lin-7 homolog A [Source:NCBI gene;Acc:100144984])

HSP 1 Score: 263.848 bits (673), Expect = 3.803e-88
Identity = 139/190 (73.16%), Postives = 167/190 (87.89%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + +PLTL RD+SRA+ELLE L+   +L  +KL  L+K+LQS+FC  +REVY++++ET+ + G  E RA ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVLDEMEARF+K +  RR
Sbjct:   65 VVQPLTLDRDVSRAIELLEKLETSGELPVQKLQSLKKVLQSEFCTAIREVYQYMHETIPVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLDEMEARFEKLRTARR 254

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Match: lin7a (lin-7 homolog A [Source:NCBI gene;Acc:100144984])

HSP 1 Score: 251.906 bits (642), Expect = 6.179e-84
Identity = 134/181 (74.03%), Postives = 160/181 (88.40%), Query Frame = 3

Query:   81 DISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            D+SRA+ELLE L+   +L  +KL  L+K+LQS+FC  +REVY++++ET+ + G  E RA ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVLDEMEARF+K +  RR
Sbjct:   48 DVSRAIELLEKLETSGELPVQKLQSLKKVLQSEFCTAIREVYQYMHETIPVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLDEMEARFEKLRTARR 228

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Match: ralbp1 (ralA binding protein 1 [Source:Xenbase;Acc:XB-GENE-1016073])

HSP 1 Score: 230.72 bits (587), Expect = 5.865e-77
Identity = 116/184 (63.04%), Postives = 137/184 (74.46%), Query Frame = 3

Query:   84 ISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPN 632
            + RA+ELLE LQ+  ++ P KL  LQ++LQSDFC  VRE     +                          SEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTP+VL+EME+RF+K + A+RR  N
Sbjct:    1 VHRAIELLEKLQRSGEVPPHKLHALQRVLQSDFCTAVREATVAAFAA------------------------SEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPRVLEEMESRFEKMRSAKRRQQN 160

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BLAST of Protein lin-7 homolog vs. Ensembl Mouse
Match: Lin7b (lin-7 homolog B (C. elegans) [Source:MGI Symbol;Acc:MGI:1330858])

HSP 1 Score: 288.5 bits (737), Expect = 4.163e-99
Identity = 147/190 (77.37%), Postives = 174/190 (91.58%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAEVRA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Mouse
Match: Lin7c (lin-7 homolog C (C. elegans) [Source:MGI Symbol;Acc:MGI:1330839])

HSP 1 Score: 283.108 bits (723), Expect = 3.979e-97
Identity = 149/194 (76.80%), Postives = 174/194 (89.69%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 635
            + EP+ L+RDI RA+ELLE LQ+  ++ P+KL  LQ++LQS+FCN VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTPKVL+EME+RF+K ++ +R   T
Sbjct:    4 LGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT 197

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Mouse
Match: Lin7a (lin-7 homolog A (C. elegans) [Source:MGI Symbol;Acc:MGI:2135609])

HSP 1 Score: 261.536 bits (667), Expect = 3.730e-88
Identity = 138/193 (71.50%), Postives = 168/193 (87.05%), Query Frame = 3

Query:   45 TF*MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            T  + +PLTL RD++RA+ELLE LQ+  ++   KL  L+K+LQS+FC  +REVY++++ET+ + G  E RA ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:   16 TLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 208

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Mouse
Match: Lin7a (lin-7 homolog A (C. elegans) [Source:MGI Symbol;Acc:MGI:2135609])

HSP 1 Score: 150.214 bits (378), Expect = 4.566e-46
Identity = 72/86 (83.72%), Postives = 81/86 (94.19%), Query Frame = 3

Query:  366 MGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            MGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    1 MGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 86

[Close]

Query:  366 MGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            MGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    1 MGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 86

[Close]

BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Match: sp|Q9Z252|LIN7B_RAT (Protein lin-7 homolog B OS=Rattus norvegicus OX=10116 GN=Lin7b PE=1 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 2.444e-98
Identity = 147/190 (77.37%), Postives = 174/190 (91.58%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAEVRA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

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BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Match: sp|O88951|LIN7B_MOUSE (Protein lin-7 homolog B OS=Mus musculus OX=10090 GN=Lin7b PE=1 SV=2)

HSP 1 Score: 288.5 bits (737), Expect = 2.912e-98
Identity = 147/190 (77.37%), Postives = 174/190 (91.58%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAEVRA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEVRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

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BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Match: sp|Q9HAP6|LIN7B_HUMAN (Protein lin-7 homolog B OS=Homo sapiens OX=9606 GN=LIN7B PE=1 SV=1)

HSP 1 Score: 285.419 bits (729), Expect = 3.688e-97
Identity = 145/190 (76.32%), Postives = 173/190 (91.05%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+RD+SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAE+RA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

[Close]

BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Match: sp|Q2KIB6|LIN7B_BOVIN (Protein lin-7 homolog B OS=Bos taurus OX=9913 GN=LIN7B PE=2 SV=1)

HSP 1 Score: 283.493 bits (724), Expect = 1.787e-96
Identity = 144/190 (75.79%), Postives = 173/190 (91.05%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + EPL L+R++SRAVELLE LQ+  +L P+KL  LQ++LQS FC+ +REVYE +Y+T+DI GSAE+RA+ATAKATVAAF ASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR+GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTP+VL+EMEARF+K ++ RR
Sbjct:    4 LVEPLGLEREVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARR 193

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BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Match: sp|Q792I0|LIN7C_RAT (Protein lin-7 homolog C OS=Rattus norvegicus OX=10116 GN=Lin7c PE=1 SV=1)

HSP 1 Score: 283.108 bits (723), Expect = 2.784e-96
Identity = 149/194 (76.80%), Postives = 174/194 (89.69%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 635
            + EP+ L+RDI RA+ELLE LQ+  ++ P+KL  LQ++LQS+FCN VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG VKLVVRYTPKVL+EME+RF+K ++ +R   T
Sbjct:    4 LGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEEMESRFEKMRSAKRRQQT 197

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BLAST of Protein lin-7 homolog vs. TrEMBL
Match: A0A267GC45 (Protein lin-7 homolog OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig001331g3 PE=3 SV=1)

HSP 1 Score: 312.383 bits (799), Expect = 1.653e-105
Identity = 166/189 (87.83%), Postives = 177/189 (93.65%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARR 620
            MAEPLTLQ+DI RAVELLE LQ CPD++ EKL  L +ILQSDFCNMVREVYEH+YETVD+ GS EVRA+ATAKATVAAFAA+EGHAHPRVVE+PKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADR G LKRGDQLLSVNG+SVENEHHEKAVDLLKAAQGTVKLVVRYTP+VLDEMEARFDK KARR
Sbjct:    1 MAEPLTLQQDIQRAVELLEKLQSCPDVQHEKLAALSRILQSDFCNMVREVYEHVYETVDVGGSPEVRASATAKATVAAFAAAEGHAHPRVVELPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADREGSLKRGDQLLSVNGVSVENEHHEKAVDLLKAAQGTVKLVVRYTPRVLDEMEARFDKHKARR 189

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BLAST of Protein lin-7 homolog vs. TrEMBL
Match: A0A4S2JC47 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_011423 PE=4 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 2.470e-105
Identity = 161/193 (83.42%), Postives = 183/193 (94.82%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPN 632
            M+EPLTL+RDI+R +ELLE LQ+CP+++P KL+ LQKILQSDFCNMVREVYEH+Y TVDI GS EV+A+ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE+EHHE+AV+LLK AQGTVKLVVRYTP++L+EMEARFDKQKARRR  N
Sbjct:    1 MSEPLTLRRDITRVIELLEILQRCPEIQPSKLVALQKILQSDFCNMVREVYEHVYATVDINGSEEVKASATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVESEHHERAVELLKLAQGTVKLVVRYTPRILEEMEARFDKQKARRRQLN 193

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BLAST of Protein lin-7 homolog vs. TrEMBL
Match: A0A075A5C3 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_00613 PE=4 SV=1)

HSP 1 Score: 311.997 bits (798), Expect = 2.470e-105
Identity = 161/193 (83.42%), Postives = 183/193 (94.82%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPN 632
            M+EPLTL+RDI+R +ELLE LQ+CP+++P KL+ LQKILQSDFCNMVREVYEH+Y TVDI GS EV+A+ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE+EHHE+AV+LLK AQGTVKLVVRYTP++L+EMEARFDKQKARRR  N
Sbjct:    1 MSEPLTLRRDITRVIELLEILQRCPEIQPSKLVALQKILQSDFCNMVREVYEHVYATVDINGSEEVKASATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVESEHHERAVELLKLAQGTVKLVVRYTPRILEEMEARFDKQKARRRQLN 193

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BLAST of Protein lin-7 homolog vs. TrEMBL
Match: C1LM76 (Lin-7 homolog B OS=Schistosoma japonicum OX=6182 GN=EWB00_010861 PE=2 SV=1)

HSP 1 Score: 306.99 bits (785), Expect = 2.653e-103
Identity = 158/190 (83.16%), Postives = 180/190 (94.74%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            MAE L+LQRDI+R +ELLE LQ+CP+++P KL  LQ+ILQSDFCNM+REVYEHIY TVDI GS EV+A+ATAKATVAAFAASEGHAHPRV+E+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNG+SVE+EHHE+AV+LLK AQGTVKLVVRYTP++L+EMEARFDKQKARRR
Sbjct:    1 MAESLSLQRDINRVLELLEILQRCPEIQPSKLAALQRILQSDFCNMIREVYEHIYTTVDINGSEEVKASATAKATVAAFAASEGHAHPRVIELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVESEHHERAVELLKLAQGTVKLVVRYTPRILEEMEARFDKQKARRR 190

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BLAST of Protein lin-7 homolog vs. TrEMBL
Match: A0A183QZ91 (Uncharacterized protein OS=Schistosoma rodhaini OX=6188 PE=4 SV=1)

HSP 1 Score: 305.064 bits (780), Expect = 1.402e-102
Identity = 159/193 (82.38%), Postives = 180/193 (93.26%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPN 632
            MAE L+LQRDI+R +ELLE LQ+CP+++P KL  LQ+ILQSDFC+M+REVYEHIY TVDI GS EV+A+ATAKATVAAFAASEGHAHPRV+E+PKT EGLGFNVMGGKEQNSPIYISRIIPGGVADR+GGLKRGDQLLSVNGISVE+EHHE+AV+LLK AQGTVKLVVRYTP++L+EMEARFDKQKARRR  N
Sbjct:    1 MAESLSLQRDINRVLELLEILQRCPEIQPSKLAALQRILQSDFCDMIREVYEHIYTTVDINGSEEVKASATAKATVAAFAASEGHAHPRVIELPKTNEGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGISVESEHHERAVELLKLAQGTVKLVVRYTPRILEEMEARFDKQKARRRQLN 193

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BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Match: lin7c (lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-2])

HSP 1 Score: 286.96 bits (733), Expect = 4.741e-98
Identity = 152/195 (77.95%), Postives = 178/195 (91.28%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT 635
            + EP+ L+RDISRA+ELL+ LQ+  ++ P+KL  LQ++LQS+FCN VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQGTVKLVVRYTPKVL+EME+RF+K + A+RR  N+
Sbjct:   51 LGEPVRLERDISRAIELLDKLQRTGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDINSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGTVKLVVRYTPKVLEEMESRFEKMRSAKRRQQNS 245

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BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Match: lin7b (lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-041011-1])

HSP 1 Score: 229.565 bits (584), Expect = 4.934e-76
Identity = 134/197 (68.02%), Postives = 158/197 (80.20%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDK-QKARRRGPNT*Y 641
            M+EPL L+R   + V             P  L G Q   Q+ + +++++VYE +Y+T+DI G  EVRA ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQG+VKLVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:   17 MSEPLCLERGHKQMVRY----------SPSGLSGKQ---QNSWFHLLQQVYEQLYDTLDIVGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKLRSARRRQQHTSY 200

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BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665])

HSP 1 Score: 206.453 bits (524), Expect = 1.572e-66
Identity = 112/144 (77.78%), Postives = 132/144 (91.67%), Query Frame = 3

Query:  192 VREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            V +VY++++ET+ + G  E +A ATAKATVAAFAASEGH+HPRVVE+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ +VKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:   65 VSQVYQYMHETITVNGCPEYQARATAKATVAAFAASEGHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARR 208

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BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Match: ENSAMXT00000041454.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02002220.1:44047:49887:-1 gene:ENSAMXG00000032771.1 transcript:ENSAMXT00000041454.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 93.5893 bits (231), Expect = 3.325e-24
Identity = 56/92 (60.87%), Postives = 62/92 (67.39%), Query Frame = 3

Query:  375 KEQNSPIYISRIIPGGVADRYGGLKRGDQLLS-VNGI-SVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDK-QKARRRGPNT*Y 641
            + QNSPIYISR+IPGGVADR    KR  QLL  VNG   VE EHHEKA            LVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:    9 RSQNSPIYISRVIPGGVADRQVDWKRAHQLLCHVNGWGCVEGEHHEKA------------LVVRYTPKVLEEMEARFEKLRSARRRQQHTSY 88

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Match: dlg2 (discs, large homolog 2 (Drosophila) [Source:NCBI gene;Acc:497638])

HSP 1 Score: 79.337 bits (194), Expect = 1.336e-16
Identity = 42/94 (44.68%), Postives = 58/94 (61.70%), Query Frame = 3

Query:  315 PRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEAR 596
            PR + + K   GLGFN++GG E    I++S I+ GG AD  G L+RGDQ+LSVNGI +    HE+A   LK A  TV ++ +Y P+     EA+
Sbjct:  372 PRKIVLHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELRRGDQILSVNGIDLRGATHEQAAAALKGAGQTVTIIAQYRPEEYGRFEAK 464

HSP 2 Score: 56.6102 bits (135), Expect = 6.862e-9
Identity = 31/84 (36.90%), Postives = 47/84 (55.95%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQ-----NSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 560
            + + +   GLGF++ GG +      +  I+I++IIPGG A   G L+  D +L VN + V    H +AV+ LK A   V+L VR
Sbjct:  126 ITLERGNSGLGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSRAVEALKVAGSIVRLYVR 209

HSP 3 Score: 55.0694 bits (131), Expect = 1.810e-8
Identity = 38/86 (44.19%), Postives = 52/86 (60.47%), Query Frame = 3

Query:  321 VVEIP--KTEEGLGFNVMGG-KEQNSP----IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVV 557
            VVEI   K  +GLGF++ GG   Q+ P    IY+++II GG A + G L+ GD+LL VN  ++E   HE+AV +LK     V L V
Sbjct:  218 VVEIKLVKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYTLEEVTHEEAVAILKNTADVVYLKV 303

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BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Match: lin7a (lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-GENE-040426-1665])

HSP 1 Score: 270.011 bits (689), Expect = 6.237e-93
Identity = 144/180 (80.00%), Postives = 163/180 (90.56%), Query Frame = 3

Query:   84 ISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            I+RA+ELLE LQ+  ++  EKL  LQ++LQS+FC  +REVYEH+YETV I GSAEVRA+ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISRIIPGGVADR GGLKRGDQLLSVNG+SVE EHHEKAV+LLK AQGTVKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    1 IARAIELLEKLQRSGEVPSEKLQALQRVLQSEFCTAIREVYEHVYETVGISGSAEVRASATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHEKAVELLKQAQGTVKLVVRYTPKVLEEMEARFEKLRTARR 180

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BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Match: LIN7B (lin-7 homolog B, crumbs cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:17788])

HSP 1 Score: 241.891 bits (616), Expect = 4.357e-82
Identity = 133/175 (76.00%), Postives = 156/175 (89.14%), Query Frame = 3

Query:  114 LQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT 635
            LQ+  ++    ++ LQK+LQSDFC +VREVYE+IYET+DI G+ E+RA ATAKATVAAFAAS+GHAHPRV E+PKT+EGLGFNVMGGKEQNSPIYISRIIPGGVADR GGLKRGDQLLSVNG+SVE EHHE+AV+LLK AQG+VKLVVRYTPKVL+EMEARF+K + A+RR  +T
Sbjct:    2 LQRSGEVPAHTILALQKVLQSDFCTVVREVYEYIYETLDITGNQEMRALATAKATVAAFAASDGHAHPRV-ELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGEHHERAVELLKQAQGSVKLVVRYTPKVLEEMEARFEKMRTAKRRQQST 175

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BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Match: gopc (golgi-associated PDZ and coiled-coil motif containing [Source:ZFIN;Acc:ZDB-GENE-030131-5086])

HSP 1 Score: 64.3142 bits (155), Expect = 1.489e-12
Identity = 40/105 (38.10%), Postives = 61/105 (58.10%), Query Frame = 3

Query:  318 RVVEIPKTEEGLGFNVM--GGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKL-VVRYTPKV-LDEMEARFDKQKARR 620
            +V+ +   +EGLG ++   GGKE   PI +S I PG  A+R GGL  GD +L+VNGI++ +  H +AV +L    G ++  VV   P V  D+  A ++ +  RR
Sbjct:  172 KVLLVKADDEGLGISITMKGGKEHGVPIIVSEIHPGLPAERCGGLYVGDAILAVNGINLRDTKHHEAVGILSQQVGEIEFEVVFVAPDVDSDDENAEYEDETGRR 276

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BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003180.1 (pep scaffold:Pmarinus_7.0:GL477326:20216:45383:1 gene:ENSPMAG00000002903.1 transcript:ENSPMAT00000003180.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 64.3142 bits (155), Expect = 3.138e-12
Identity = 31/80 (38.75%), Postives = 48/80 (60.00%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAA--QGTVKLVV 557
            + + + E G GF ++GG+E   PI I  I+PGG AD  G ++ GD+L+SV+GI V  + H   + L++ A   G V L +
Sbjct:  406 IHLRRQEAGFGFRILGGEELGQPIRIGAIVPGGSADLDGRMRSGDELVSVDGIPVSGKSHRSVIGLMQQAARNGLVALTI 485

HSP 2 Score: 53.5286 bits (127), Expect = 1.512e-8
Identity = 24/70 (34.29%), Postives = 43/70 (61.43%), Query Frame = 3

Query:  321 VVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKA 530
            V E+ +   G GF++ GGKE +  ++I R+   G A R   ++ GDQ++ +NG S  +  H +A++L+K+
Sbjct:  706 VAELERGNTGFGFSIRGGKEYSMDLFILRVAEEGPAIRQSRMRVGDQIMEINGESTRDMMHARAIELIKS 775

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Match: sntg2 (syntrophin, gamma 2 [Source:ZFIN;Acc:ZDB-GENE-060526-196])

HSP 1 Score: 61.6178 bits (148), Expect = 2.291e-11
Identity = 37/96 (38.54%), Postives = 53/96 (55.21%), Query Frame = 3

Query:  297 SEGHAHPRVVEIPKTE-EGLGFNVMGGKEQNSPIYISRIIPGGV--ADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKV 575
            S+  A  R V + + E  G G ++ GG E   P+ IS+I+      AD+ G L  GD +L +NGI+VEN  HE+ V +L+ A   V   VRY  K+
Sbjct:   63 SQCSAKERSVTLRRQEIGGFGLSIKGGAEYRVPVVISKIMKDQADPADQTGMLFIGDAILRINGINVENATHEEVVQVLQTAGDEVTFTVRYLRKI 158

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Match: EDO47722 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLN6])

HSP 1 Score: 273.478 bits (698), Expect = 5.839e-94
Identity = 142/189 (75.13%), Postives = 169/189 (89.42%), Query Frame = 3

Query:   57 AEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
             EPLTL RD++RAVELL+ LQ   ++ P KL  LQK+L+S+FC  +REVYEH+YETV+I+GS E+RA ATAKAT+AAFAASEGHAHPRVVE+PKT+EGLGFNVMGG+EQNSPIYISRIIPGGVADR GGLKRGDQLLSVNG+SVE E+HEKAVDLLK AQG+V+LVV+YTPK+L+EMEARF+ Q+  R+
Sbjct:    4 TEPLTLARDVNRAVELLQKLQNNGNIPPAKLQALQKVLESEFCQAIREVYEHVYETVEIQGSPELRAQATAKATIAAFAASEGHAHPRVVELPKTDEGLGFNVMGGREQNSPIYISRIIPGGVADRQGGLKRGDQLLSVNGVSVEGENHEKAVDLLKEAQGSVRLVVKYTPKLLEEMEARFNSQRGSRK 192

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Match: EDO33706 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRG3])

HSP 1 Score: 72.0182 bits (175), Expect = 1.941e-14
Identity = 38/92 (41.30%), Postives = 55/92 (59.78%), Query Frame = 3

Query:  297 SEGHAHPRVVEIPKTEEGLGFNVMGGKEQ---NSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRY 563
            SE     +++E+ +  EGLGF+++GG      + PIY+  + P G A R G LKRGDQ+++VNG S+    HE AV  LK  +G + L V Y
Sbjct: 1742 SESPLQTKIIELERGPEGLGFSIVGGHGSPHGDLPIYVKTVFPTGAASRDGRLKRGDQIIAVNGQSLVGVSHESAVSQLKKTRGKIILTVLY 1833

HSP 2 Score: 55.4546 bits (132), Expect = 6.426e-9
Identity = 35/97 (36.08%), Postives = 54/97 (55.67%), Query Frame = 3

Query:  318 RVVEIPKTEE-GLGFNVMGGKE-QNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRY-----TPKVLDEM 587
            RVVE+ +  E GLG ++ G K  Q   +++  ++      R G LK GDQ+L V+G  + N  HE+AV++++ A+  V+ VVR       P  LD M
Sbjct: 1228 RVVELRREPEVGLGISIAGNKRGQRQGVHVRHVLENSSVARLGELKAGDQILEVDGHDLRNASHEEAVEVIRRARSPVRFVVRTIQDKEDPLSLDTM 1324

HSP 3 Score: 50.447 bits (119), Expect = 2.986e-7
Identity = 26/70 (37.14%), Postives = 44/70 (62.86%), Query Frame = 3

Query:  348 GLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVV 557
            GLGF ++GG+  +S + I  I+PGGVAD+ G L+  DQ++ +  ++V     E+   +L+ A   V+LV+
Sbjct:  307 GLGFGIIGGR--SSGVSIKTILPGGVADKDGRLQEHDQIMQIGDVNVGGMGSEQVAQVLRDAGSHVRLVI 374

HSP 4 Score: 50.0618 bits (118), Expect = 3.618e-7
Identity = 31/74 (41.89%), Postives = 48/74 (64.86%), Query Frame = 3

Query:  348 GLGFNVMGGKEQNSP---IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENE-HHEKAVDLLKAAQGTVKLVV 557
            GLGF+V+G K +N     I+I  I   GVA R G L+  DQ+LS++G  +++   HE+A+ LL+  +G V+L+V
Sbjct:  174 GLGFSVVGLKSENRGELGIFIQEIQEEGVAGRDGRLRESDQILSIDGQQLDSGISHEEAIVLLQKTRGEVELIV 247

HSP 5 Score: 49.6766 bits (117), Expect = 4.803e-7
Identity = 33/94 (35.11%), Postives = 57/94 (60.64%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQNSP----IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAA-QGTVKLVVRYTPKVLDEME 590
            VE+ K ++GLGF+++  ++ ++P    I I  ++ GGVA++ G L  GD+L+SVN +++E+   + AV  LK   +G V + V     V D+ E
Sbjct:  937 VELEKADKGLGFSILDYQDPSNPEKTVIVIRSLVHGGVAEQDGSLHPGDRLMSVNEVNLEHASLDFAVQTLKGTNRGNVIIGVAKPIPVPDDYE 1030

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Match: EDO46649 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPA4])

HSP 1 Score: 67.781 bits (164), Expect = 2.888e-13
Identity = 38/90 (42.22%), Postives = 51/90 (56.67%), Query Frame = 3

Query:  303 GHAHPRVVEIPKTE-EGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTP 569
            G   PR V + K + EGLG ++ GGKE   PI IS I  G  A R GGL  GD +L+VNGI +++  H  AV +L +  G + + V Y  
Sbjct:  268 GIGEPRTVIVNKDKTEGLGISITGGKEHGVPILISEIHDGMPAARCGGLYVGDAILAVNGIDLQDAKHNDAVKILSSIHGEITMEVLYVA 357

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Match: EDO42539 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S157])

HSP 1 Score: 62.3882 bits (150), Expect = 2.862e-11
Identity = 30/79 (37.97%), Postives = 52/79 (65.82%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 560
            +E+ +  +G GF++ GG+E + PIY+ +I  GGVAD  G +K GD++L +NG S ++  H  A+ +++     V+LV+R
Sbjct: 1052 IELIRKNQGYGFSIRGGQEMDMPIYVLKIAEGGVADLDGRIKVGDEVLEINGRSTQHMLHTDAISMIRGGS-KVRLVLR 1129

HSP 2 Score: 60.4622 bits (145), Expect = 1.268e-10
Identity = 32/81 (39.51%), Postives = 50/81 (61.73%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAA--QGTVKLVVR 560
            + + + E G GF ++GGKE N+ + I  I+ G  A   G L+RGD++L V+G+SV + +H   + L+K+A   G V L VR
Sbjct:  685 ITLHRGESGFGFRIVGGKEDNTQVAIGTIVDGTPAAADGRLRRGDEILYVDGVSVIDGYHRDVISLMKSAAQNGQVTLGVR 765

HSP 3 Score: 52.7582 bits (125), Expect = 5.343e-8
Identity = 25/69 (36.23%), Postives = 40/69 (57.97%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKA 530
             E+ K   G GF ++GG +    + I  I+P G A + G L+ GD L+ VNG SV N+ H++ V + ++
Sbjct:  345 TELMKGFRGFGFTIIGGDQSGELLQIKSIVPDGAAAKDGKLRTGDALIKVNGRSVVNKTHQEVVSMFQS 413

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Match: EDO46059 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RR65])

HSP 1 Score: 59.6918 bits (143), Expect = 4.923e-11
Identity = 33/82 (40.24%), Postives = 50/82 (60.98%), Query Frame = 3

Query:  324 VEIPKTEEGLGFNVMGGKEQ-----NSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLV 554
            + + +   GLGF++ GG +      +  IYI+++IPGG A + G L+  D +LSVNG +  +  H++AVD LKAA   V LV
Sbjct:    7 ITLERGGSGLGFSIAGGTDNPHVDDDFGIYITKVIPGGAAAQDGRLQVNDCILSVNGTNTVDIEHQQAVDALKAAGSQVTLV 88

HSP 2 Score: 57.3806 bits (137), Expect = 3.576e-10
Identity = 35/79 (44.30%), Postives = 52/79 (65.82%), Query Frame = 3

Query:  336 KTEEGLGFNVMGGK-EQNSP----IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVV 557
            K  +GLGF++ GG   Q+ P    IYI++II GG A + G L+ GD+++SVN  ++E+  HE AV +LKA +  V +VV
Sbjct:  106 KGSKGLGFSIAGGSGNQHVPGDNGIYITKIIEGGAAQQDGRLQVGDKIISVNLQNLEDVSHEDAVQVLKATKERVTIVV 184

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Match: lin7b (lin-7 homolog B, crumbs cell polarity complex component [Source:NCBI gene;Acc:101174999])

HSP 1 Score: 273.092 bits (697), Expect = 6.089e-93
Identity = 148/197 (75.13%), Postives = 171/197 (86.80%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT*Y 641
            MAEPL L+RD+ R +ELL+ LQ+  +L P KL  LQ++LQS FC  +REVYE +Y+T+DI G  EVRA ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:   17 MAEPLCLERDVCRVIELLDRLQRTGELPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIVGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSY 213

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Match: lin7a (lin-7 homolog A, crumbs cell polarity complex component [Source:NCBI gene;Acc:101166430])

HSP 1 Score: 263.462 bits (672), Expect = 3.167e-89
Identity = 139/190 (73.16%), Postives = 168/190 (88.42%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRR 623
            + +PLTL+RD++RA+ELLE LQ+  D+   KL  L+K+LQS+FC  +REVY++++ET+ + G  E +A ATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFNVMGGKEQNSPIYISRIIPGGVA+R+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAA+ TVKLVVRYTPKVL+EMEARF+K +  RR
Sbjct:    4 VVQPLTLERDVARAIELLEKLQESGDVPGHKLQSLKKVLQSEFCTAIREVYQYMHETITVNGCPEYQARATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKDTVKLVVRYTPKVLEEMEARFEKLRTARR 193

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Match: lin7b (lin-7 homolog B, crumbs cell polarity complex component [Source:NCBI gene;Acc:101174999])

HSP 1 Score: 253.447 bits (646), Expect = 1.802e-85
Identity = 139/183 (75.96%), Postives = 160/183 (87.43%), Query Frame = 3

Query:   96 VELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT*Y 641
            +ELL+ LQ+  +L P KL  LQ++LQS FC  +REVYE +Y+T+DI G  EVRA ATAKATVAAFAASEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:   21 IELLDRLQRTGELPPPKLQALQRVLQSKFCAAIREVYEQLYDTLDIVGGPEVRAQATAKATVAAFAASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSY 203

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Match: lin7c (60S acidic ribosomal protein P2 [Source:NCBI gene;Acc:101168608])

HSP 1 Score: 253.062 bits (645), Expect = 3.482e-84
Identity = 135/169 (79.88%), Postives = 156/169 (92.31%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVR 560
            + EP+ L+RDI+RA+ELL+ LQ+  ++ P+KL  LQ++LQS+FCN VREVYEH+YETVDI  S EVRANATAKATVAAFAASEGH+HPRVVE+PKTEEGLGFN+MGGKEQNSPIYISRIIPGG+ADR+GGLKRGDQLLSVNG+SVE EHHEKAV+LLKAAQGTVKLVVR
Sbjct:    4 LGEPVRLERDINRAIELLDKLQRTGEVPPQKLQALQRVLQSEFCNAVREVYEHVYETVDINSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYISRIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGTVKLVVR 172

[Close]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Match: lin7b (lin-7 homolog B, crumbs cell polarity complex component [Source:NCBI gene;Acc:101174999])

HSP 1 Score: 243.432 bits (620), Expect = 5.384e-82
Identity = 124/197 (62.94%), Postives = 145/197 (73.60%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQK-ARRRGPNT*Y 641
            MAEPL L+RD+ R +ELL+ LQ+  +L P KL  LQ++LQS FC  +RE     +                          SEGHAHPRVVE+PKT+EGLGFN+MGGKEQNSPIYISR+IPGGVADR GGLKRGDQLLSVNG+SVE E HEKAV+LLKAAQG+VKLVVRYTPKVL+EMEARF+K + ARRR  +T Y
Sbjct:    4 MAEPLCLERDVCRVIELLDRLQRTGELPPPKLQALQRVLQSKFCAAIREATVAAFAA------------------------SEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRQGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPKVLEEMEARFEKMRSARRRQQHTSY 176

[Close]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Match: SMESG000057909.1 (SMESG000057909.1)

HSP 1 Score: 362.459 bits (929), Expect = 6.478e-129
Identity = 193/194 (99.48%), Postives = 194/194 (100.00%), Query Frame = 3

Query:   54 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRXXXXXXXXXXXXXXSEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 635
            MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRA+ATAKATVAAFAASEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT
Sbjct:    1 MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREVYEHIYETVDIEGSAEVRASATAKATVAAFAASEGHAHPRVVEIPKTEEGLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT 194

[Close]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Match: SMESG000005336.1 (SMESG000005336.1)

HSP 1 Score: 67.781 bits (164), Expect = 6.362e-13
Identity = 43/107 (40.19%), Postives = 60/107 (56.07%), Query Frame = 3

Query:  297 SEGHAHPRVVEIPKTEE-GLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKA 614
            S+ +   R++ I K E  GLG ++ GGKE   PI IS+I  G  AD+ G L  GD +LSVNG  + +  H++AV +LK A   V L V+Y    + E+   F K  A
Sbjct:   70 SDINGQKRMIRITKEESNGLGISIKGGKENKMPILISKIFKGMSADKTGELYVGDAILSVNGEDLRDATHDEAVKVLKKAGRIVDLEVKY----MHEVSPYFKKNSA 172

[Close]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Match: SMESG000034854.1 (SMESG000034854.1)

HSP 1 Score: 65.0846 bits (157), Expect = 6.451e-12
Identity = 34/108 (31.48%), Postives = 63/108 (58.33%), Query Frame = 3

Query:  315 PRVVEIPKTEE--GLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPN 632
            PR+V + +  E  G GFN++GG++++  I++S IIP G+AD+ G +  GD++  VNG  +    H++A  LLK +  T++L++          E++F+    + +  N
Sbjct:  498 PRIVVLSRPNETVGFGFNIVGGEDEDG-IFVSFIIPSGIADKNGNIFVGDRIWQVNGTDISIATHDEAASLLKGSGKTLELLLTTDMNEYVAFESKFNWNTHKNKDNN 604

HSP 2 Score: 62.7734 bits (151), Expect = 4.170e-11
Identity = 41/99 (41.41%), Postives = 54/99 (54.55%), Query Frame = 3

Query:  315 PRVVE--IPKTEEGLGFNVMGGKEQ-----NSP-IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEM 587
            P V+E  I K   G GF+V GG +      N P IY+++I PGG  D  G L   DQ+LSVNGI++    HE AV  LK A   + LV++  P +   M
Sbjct:  172 PIVMEAVILKGSTGFGFSVAGGIDNPYFHLNDPGIYVTKITPGGSVDLSGSLNIDDQILSVNGINMTYLTHEAAVSALKEAGDELHLVIQRDPTLKHRM 270

[Close]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Match: SMESG000034854.1 (SMESG000034854.1)

HSP 1 Score: 65.0846 bits (157), Expect = 6.709e-12
Identity = 34/108 (31.48%), Postives = 63/108 (58.33%), Query Frame = 3

Query:  315 PRVVEIPKTEE--GLGFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPN 632
            PR+V + +  E  G GFN++GG++++  I++S IIP G+AD+ G +  GD++  VNG  +    H++A  LLK +  T++L++          E++F+    + +  N
Sbjct:  510 PRIVVLSRPNETVGFGFNIVGGEDEDG-IFVSFIIPSGIADKNGNIFVGDRIWQVNGTDISIATHDEAASLLKGSGKTLELLLTTDMNEYVAFESKFNWNTHKNKDNN 616

HSP 2 Score: 62.7734 bits (151), Expect = 4.417e-11
Identity = 41/99 (41.41%), Postives = 54/99 (54.55%), Query Frame = 3

Query:  315 PRVVE--IPKTEEGLGFNVMGGKEQ-----NSP-IYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVVRYTPKVLDEM 587
            P V+E  I K   G GF+V GG +      N P IY+++I PGG  D  G L   DQ+LSVNGI++    HE AV  LK A   + LV++  P +   M
Sbjct:  184 PIVMEAVILKGSTGFGFSVAGGIDNPYFHLNDPGIYVTKITPGGSVDLSGSLNIDDQILSVNGINMTYLTHEAAVSALKEAGDELHLVIQRDPTLKHRM 282

[Close]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Match: SMESG000081127.1 (SMESG000081127.1)

HSP 1 Score: 63.5438 bits (153), Expect = 2.126e-11
Identity = 37/96 (38.54%), Postives = 56/96 (58.33%), Query Frame = 3

Query:  306 HAHPRVVEIPKTEEGLGFNVMGG-------KEQNSPIY-----ISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHHEKAVDLLKAAQGTVKLVV 557
            +  PRVV IPK++ G GFNV G        K  N  +Y     +S ++P G A++  GL + D++L VNG++VE   H++ VDL+K+   T+ L V
Sbjct:   16 YKKPRVVIIPKSQSGFGFNVRGQVGEGGQLKSINGELYAPLQQVSAVLPNGAAEK-AGLLKYDRILEVNGVNVEGATHKQVVDLIKSGGETLILTV 110

The following BLAST results are available for this feature:

BLAST of Protein lin-7 homolog vs. Ensembl Human
BLAST of Protein lin-7 homolog vs. Ensembl Celegans
BLAST of Protein lin-7 homolog vs. Ensembl Fly
BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
BLAST of Protein lin-7 homolog vs. Ensembl Mouse
BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
BLAST of Protein lin-7 homolog vs. TrEMBL
BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
BLAST of Protein lin-7 homolog vs. Ensembl Yeast
BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
BLAST of Protein lin-7 homolog vs. Ensembl Medaka
BLAST of Protein lin-7 homolog vs. Planmine SMEST

BLAST of Protein lin-7 homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LIN7B	7.679e-98	76.32	lin-7 homolog B, crumbs cell polarity complex comp...	[more]
LIN7C	5.796e-97	76.80	lin-7 homolog C, crumbs cell polarity complex comp...	[more]
LIN7A	5.432e-88	71.50	lin-7 homolog A, crumbs cell polarity complex comp...	[more]
LIN7C	7.264e-83	62.37	lin-7 homolog C, crumbs cell polarity complex comp...	[more]
LIN7A	1.703e-60	67.55	lin-7 homolog A, crumbs cell polarity complex comp...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lin-7	3.936e-78	67.76	pep chromosome:WBcel235:II:14346877:14348792:-1 ge...	[more]
lin-7	5.834e-76	67.76	pep chromosome:WBcel235:II:14347162:14348792:-1 ge...	[more]
dlg-1	1.062e-19	45.36	Disks large homolog 1 [Source:UniProtKB/Swiss-Pro...	[more]
stn-2	3.020e-12	42.05	SynTrophiN [Source:UniProtKB/TrEMBL;Acc:Q5WRR6]	[more]
stn-2	3.112e-12	42.05	SynTrophiN [Source:UniProtKB/TrEMBL;Acc:Q5WRR6]	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
veli	1.106e-95	79.37	gene:FBgn0039269 transcript:FBtr0084787	[more]
veli	1.061e-84	62.50	gene:FBgn0039269 transcript:FBtr0301664	[more]
dlg1	9.088e-19	46.08	gene:FBgn0001624 transcript:FBtr0073488	[more]
dlg1	1.021e-18	46.08	gene:FBgn0001624 transcript:FBtr0301288	[more]
dlg1	1.084e-18	46.08	gene:FBgn0001624 transcript:FBtr0073490	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lin7c	4.983e-97	77.44	lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7c	9.132e-97	75.76	lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7b	5.440e-93	75.13	lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7a	4.910e-88	72.87	lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7b	9.614e-63	74.13	lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSXETT00000028683.1	1.056e-95	77.37	lin-7 homolog B [Source:NCBI gene;Acc:100491827]	[more]
ralbp1	1.077e-95	76.80	ralA binding protein 1 [Source:Xenbase;Acc:XB-GENE...	[more]
lin7a	3.803e-88	73.16	lin-7 homolog A [Source:NCBI gene;Acc:100144984]	[more]
lin7a	6.179e-84	74.03	lin-7 homolog A [Source:NCBI gene;Acc:100144984]	[more]
ralbp1	5.865e-77	63.04	ralA binding protein 1 [Source:Xenbase;Acc:XB-GENE...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Lin7b	4.163e-99	77.37	lin-7 homolog B (C. elegans) [Source:MGI Symbol;Ac...	[more]
Lin7c	3.979e-97	76.80	lin-7 homolog C (C. elegans) [Source:MGI Symbol;Ac...	[more]
Lin7a	3.730e-88	71.50	lin-7 homolog A (C. elegans) [Source:MGI Symbol;Ac...	[more]
Lin7a	4.566e-46	83.72	lin-7 homolog A (C. elegans) [Source:MGI Symbol;Ac...	[more]
Lin7a	4.566e-46	83.72	lin-7 homolog A (C. elegans) [Source:MGI Symbol;Ac...	[more]

BLAST of Protein lin-7 homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9Z252\|LIN7B_RAT	2.444e-98	77.37	Protein lin-7 homolog B OS=Rattus norvegicus OX=10...	[more]
sp\|O88951\|LIN7B_MOUSE	2.912e-98	77.37	Protein lin-7 homolog B OS=Mus musculus OX=10090 G...	[more]
sp\|Q9HAP6\|LIN7B_HUMAN	3.688e-97	76.32	Protein lin-7 homolog B OS=Homo sapiens OX=9606 GN...	[more]
sp\|Q2KIB6\|LIN7B_BOVIN	1.787e-96	75.79	Protein lin-7 homolog B OS=Bos taurus OX=9913 GN=L...	[more]
sp\|Q792I0\|LIN7C_RAT	2.784e-96	76.80	Protein lin-7 homolog C OS=Rattus norvegicus OX=10...	[more]

BLAST of Protein lin-7 homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A267GC45	1.653e-105	87.83	Protein lin-7 homolog OS=Macrostomum lignano OX=28...	[more]
A0A4S2JC47	2.470e-105	83.42	Uncharacterized protein OS=Opisthorchis felineus O...	[more]
A0A075A5C3	2.470e-105	83.42	Uncharacterized protein OS=Opisthorchis viverrini ...	[more]
C1LM76	2.653e-103	83.16	Lin-7 homolog B OS=Schistosoma japonicum OX=6182 G...	[more]
A0A183QZ91	1.402e-102	82.38	Uncharacterized protein OS=Schistosoma rodhaini OX...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lin7c	4.741e-98	77.95	lin-7 homolog C (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7b	4.934e-76	68.02	lin-7 homolog B (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
lin7a	1.572e-66	77.78	lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
ENSAMXT00000041454.1	3.325e-24	60.87	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]
dlg2	1.336e-16	44.68	discs, large homolog 2 (Drosophila) [Source:NCBI g...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lin7a	6.237e-93	80.00	lin-7 homolog A (C. elegans) [Source:ZFIN;Acc:ZDB-...	[more]
LIN7B	4.357e-82	76.00	lin-7 homolog B, crumbs cell polarity complex comp...	[more]
gopc	1.489e-12	38.10	golgi-associated PDZ and coiled-coil motif contain...	[more]
ENSPMAT00000003180.1	3.138e-12	38.75	pep scaffold:Pmarinus_7.0:GL477326:20216:45383:1 g...	[more]
sntg2	2.291e-11	38.54	syntrophin, gamma 2 [Source:ZFIN;Acc:ZDB-GENE-0605...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Protein lin-7 homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO47722	5.839e-94	75.13	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33706	1.941e-14	41.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46649	2.888e-13	42.22	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42539	2.862e-11	37.97	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46059	4.923e-11	40.24	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Protein lin-7 homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
lin7b	6.089e-93	75.13	lin-7 homolog B, crumbs cell polarity complex comp...	[more]
lin7a	3.167e-89	73.16	lin-7 homolog A, crumbs cell polarity complex comp...	[more]
lin7b	1.802e-85	75.96	lin-7 homolog B, crumbs cell polarity complex comp...	[more]
lin7c	3.482e-84	79.88	60S acidic ribosomal protein P2 [Source:NCBI gene;...	[more]
lin7b	5.384e-82	62.94	lin-7 homolog B, crumbs cell polarity complex comp...	[more]

BLAST of Protein lin-7 homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000057909.1	6.478e-129	99.48	SMESG000057909.1	[more]
SMESG000005336.1	6.362e-13	40.19	SMESG000005336.1	[more]
SMESG000034854.1	6.451e-12	31.48	SMESG000034854.1	[more]
SMESG000034854.1	6.709e-12	31.48	SMESG000034854.1	[more]
SMESG000081127.1	2.126e-11	38.54	SMESG000081127.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30024725 ID=SMED30024725|Name=Protein lin-7 homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=722bp
GTTTTATTACAATTTAGAGTTTTTAAATAAACAATTATAAGGAAACTTTT
TAAATGGCTGAGCCATTAACACTACAAAGAGATATATCTAGGGCCGTTGA
ACTTCTTGAGTCATTACAGAAATGTCCGGATTTGAAACCAGAAAAGTTAA
TTGGTTTACAAAAAATTTTGCAGTCCGATTTCTGTAACATGGTCCGAGAA
GTTTATGAACATATTTATGAAACAGTAGATATTGAAGGGTCTGCTGAGGT
TAGAGCTAATGCAACTGCTAAAGCTACTGTAGCGGCTTTTGCTGCCAGTG
AAGGGCATGCACATCCAAGAGTGGTTGAAATTCCAAAAACTGAAGAAGGT
TTAGGCTTTAATGTTATGGGTGGAAAAGAACAAAATTCTCCAATTTATAT
CAGTAGAATTATTCCAGGAGGTGTAGCTGACAGATATGGTGGATTAAAAC
GTGGTGATCAGCTTCTTTCTGTAAATGGAATATCTGTAGAAAATGAACAT
CATGAAAAGGCTGTGGATTTATTAAAAGCTGCTCAAGGAACTGTTAAATT
GGTTGTTCGCTACACTCCTAAAGTTTTGGATGAAATGGAAGCTCGGTTCG
ATAAACAAAAAGCAAGGAGACGCGGACCAAACACTTAATATTTTTAGAAA
TTTATTTTTTTTGCAAACATTGTGATTACCTTTTATCAGTAAATATATTG
TTTAGCTTTAAAAAAAAGATCG

protein sequence of SMED30024725-orf-1

>SMED30024725-orf-1 ID=SMED30024725-orf-1|Name=SMED30024725-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=195bp
MAEPLTLQRDISRAVELLESLQKCPDLKPEKLIGLQKILQSDFCNMVREV
YEHIYETVDIEGSAEVRANATAKATVAAFAASEGHAHPRVVEIPKTEEGL
GFNVMGGKEQNSPIYISRIIPGGVADRYGGLKRGDQLLSVNGISVENEHH
EKAVDLLKAAQGTVKLVVRYTPKVLDEMEARFDKQKARRRGPNT*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **cellular component**
Term	Definition
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0030054	cell junction
GO:0097025	MPP7-DLG1-LIN7 complex
GO:0005911	cell-cell junction
GO:0016323	basolateral plasma membrane
GO:0045202	synapse
GO:0098793	presynapse

Vocabulary: **biological process**
Term	Definition
GO:0006887	exocytosis
GO:0015031	protein transport
GO:0007269	neurotransmitter secretion
GO:0045199	maintenance of epithelial cell apical/basal polarity
GO:1903361	protein localization to basolateral plasma membrane

Vocabulary: **molecular function**
Term	Definition
GO:0097016	L27 domain binding
GO:0005515	protein binding

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000070	intestinal phagocyte
PLANA:0000099	neuron

Vocabulary: **INTERPRO**
Term	Definition
IPR017365	LIN7
IPR036034	PDZ_sf
IPR036892	L27_dom_sf
IPR004172	L27_dom
IPR001478	PDZ
IPR014775	L27_C

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 98..172 e-value: 4.0E-23 score: 92.8
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 91..169 e-value: 7.7E-20 score: 71.0
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 90..172 score: 22.978
IPR004172	L27 domain	SMART	SM00569	L27_neu3	coord: 10..65 e-value: 2.4E-10 score: 50.4
IPR004172	L27 domain	PROSITE	PS51022	L27	coord: 7..62 score: 16.482
IPR017365	Protein lin-7	PIRSF	PIRSF038039	UCP038039_Lin-7_homol	coord: 1..100 e-value: 4.3E-50 score: 168.0 coord: 98..191 e-value: 8.0E-56 score: 186.7
None	No IPR available	GENE3D	G3DSA:1.10.287.650		coord: 5..61 e-value: 1.7E-29 score: 103.1
None	No IPR available	PANTHER	PTHR14063	FAMILY NOT NAMED	coord: 2..190
None	No IPR available	PANTHER	PTHR14063:SF5	PROTEIN LIN-7 HOMOLOG C	coord: 2..190
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 88..169 e-value: 3.24909E-29 score: 101.875
IPR036034	PDZ superfamily	GENE3D	G3DSA:2.30.42.10		coord: 85..192 e-value: 3.0E-31 score: 109.8
IPR036034	PDZ superfamily	SUPERFAMILY	SSF50156	PDZ domain-like	coord: 85..178
IPR014775	L27 domain, C-terminal	PFAM	PF02828	L27	coord: 11..63 e-value: 1.2E-18 score: 66.6
IPR036892	L27 domain superfamily	SUPERFAMILY	SSF101288	L27 domain	coord: 5..60

Main menu

Protein lin-7 homolog

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 6

Owlery

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