RanBP-type and C3HC4-type zinc finger-containing protein 1

Overview
NameRanBP-type and C3HC4-type zinc finger-containing protein 1
Smed IDSMED30024723
Length (bp)1756
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of RanBP-type and C3HC4-type zinc finger-containing protein 1 (SMED30024723) t-SNE clustered cells

Violin plots show distribution of expression levels for RanBP-type and C3HC4-type zinc finger-containing protein 1 (SMED30024723) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of RanBP-type and C3HC4-type zinc finger-containing protein 1 (SMED30024723) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for RanBP-type and C3HC4-type zinc finger-containing protein 1 (SMED30024723) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024723

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30024723SMESG000080622.1 SMESG000037051.1 SMESG000028834.1 SMESG000018862.1 dd_Smed_v4_16339_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024723SMESG000080622.1 SMESG000037051.1 SMESG000028834.1 SMESG000018862.1 dd_Smed_v4_16339_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30024723SMESG000080622.1 SMESG000037051.1 SMESG000028834.1 SMESG000018862.1 dd_Smed_v4_16339_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Human
Match: RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864])

HSP 1 Score: 38.891 bits (89), Expect = 6.329e-8
Identity = 28/109 (25.69%), Postives = 52/109 (47.71%), Query Frame = 2 
Query:  848 FCCKYESCSGF-WDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKK---------PQYLEAKLVK*KLKNNPSVKCLCGKVLIQ-NGGCGSLHCPNCGVHVCVFT 1141
            + CK   C G+ +  +  N F  C  C H+NCL C+ IHE M+C ++++                +++K  L+   +++C   ++++Q   GC  + C  C   +C  T
Sbjct:  369 YHCKTPDCKGWCFFEDDVNEF-TCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVT 476

HSP 2 Score: 38.5058 bits (88), Expect = 6.329e-8
Identity = 20/64 (31.25%), Postives = 33/64 (51.56%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  SCP       C+  + ER+I  L
Sbjct:  282 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVSCPFIDNTYSCSGKLLEREIKAL 344
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Human
Match: RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864])

HSP 1 Score: 38.891 bits (89), Expect = 7.228e-8
Identity = 26/108 (24.07%), Postives = 48/108 (44.44%), Query Frame = 2 
Query:  848 FCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKK---------PQYLEAKLVK*KLKNNPSVKCLCGKVLIQ-NGGCGSLHCPNCGVHVCVFT 1141
            + CK   C G+           C  C H+NCL C+ IHE M+C ++++                +++K  L+   +++C   ++++Q   GC  + C  C   +C  T
Sbjct:  327 YHCKTPDCKGWCFFEDDVNEFTCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVT 434

HSP 2 Score: 38.1206 bits (87), Expect = 7.228e-8
Identity = 20/64 (31.25%), Postives = 33/64 (51.56%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  SCP       C+  + ER+I  L
Sbjct:  240 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVSCPFIDNTYSCSGKLLEREIKAL 302
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Zebrafish
Match: shrprbck1r (sharpin and rbck1 related [Source:NCBI gene;Acc:569903])

HSP 1 Score: 40.817 bits (94), Expect = 4.238e-8
Identity = 28/100 (28.00%), Postives = 52/100 (52.00%), Query Frame = 3 
Query:  540 EFLKSRNKEQLKSF-----ILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
            ++ ++R  E+ ++F     +   + +PNP+   C IC   +   EG++LR C H +CKEC    +++V  +S   + +CP       C+  + ER+I  L
Sbjct:  453 QYQQARETERRENFARLVQMDGQDLVPNPERVECRICYVELESGEGVLLRECLHCFCKEC----LRSVILMSEDPQVACPYRDESYACDCVLQEREIRAL 548

HSP 2 Score: 36.5798 bits (83), Expect = 4.238e-8
Identity = 31/101 (30.69%), Postives = 48/101 (47.52%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            E  + C    C G W +  +  N FH C  C   NCL C+ IHE M+C  ++     L A+ +     N+ + +      K L+ +G   ++HCP CG+ V
Sbjct:  570 EGSYHCATADCPG-WCVYEDTVNTFH-CPVCKKQNCLLCKAIHEGMNCKQYQDD---LTARAI-----NDSAARRTRDLLKTLVNSG--EAMHCPQCGIIV 658
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Xenopus
Match: ENSXETT00000033448.1 (RanBP-type and C3HC4-type zinc finger containing 1 [Source:NCBI gene;Acc:100491300])

HSP 1 Score: 36.1946 bits (82), Expect = 2.615e-6
Identity = 29/124 (23.39%), Postives = 54/124 (43.55%), Query Frame = 2 
Query:  800 IEKITHIYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSC----NDFRKKPQYLEA-----KLVK*KLKNNPSVKCLCGKVLIQ-NGGCGSLHCPNCGVHVCVFT 1141
            +E+   +  S+  + Y C +   C G+     +     C  C   NCL C+ IH+ M+C    +D R + Q   A      ++K  ++   ++ C   ++++Q   GC  + C  C   +C  T
Sbjct:  126 LERGLVVAESRSHDSYHC-RTADCRGWCVYEDSVNEFTCPICHAQNCLTCKAIHDGMNCREYQDDLRIRAQNDAAARQTNDMLKTLVQTGEAMYCPVCQIIVQKKDGCDWIRCTMCQTEICWVT 248

HSP 2 Score: 35.8094 bits (81), Expect = 2.615e-6
Identity = 23/73 (31.51%), Postives = 34/73 (46.58%), Query Frame = 3 
Query:  597 FIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
             IPN +   C IC   +    G++LR C H +C+EC +  + N       SCP       CN  + +R+I  L
Sbjct:   45 LIPNQEPIDCLICFSEVPVGGGVLLRECLHSFCREC-LRQLVNCCEEPEVSCPFRDETYACNSKLQQREIRAL 116
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Mouse
Match: Rbck1 (RanBP-type and C3HC4-type zinc finger containing 1 [Source:MGI Symbol;Acc:MGI:1344372])

HSP 1 Score: 37.7354 bits (86), Expect = 3.718e-7
Identity = 28/98 (28.57%), Postives = 50/98 (51.02%), Query Frame = 2 
Query:  848 FCCKYESCSG--FWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            + CK   C G  F++ +  N F  C  C  +NCL C+ IHE+M+C +++          +  + +N+ + +      KV++Q G   ++HCP C + V
Sbjct:  367 YHCKTPDCRGWCFFE-DDVNEF-TCPVCTRVNCLLCKAIHEHMNCREYQDD--------LALRAQNDVAARQTTEMLKVMLQQG--EAMHCPQCRIVV 452

HSP 2 Score: 36.5798 bits (83), Expect = 3.718e-7
Identity = 19/64 (29.69%), Postives = 32/64 (50.00%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  +CP       C   + ER+I  L
Sbjct:  280 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVACPFIDSTYSCPGKLLEREIRAL 342
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Mouse
Match: Rbck1 (RanBP-type and C3HC4-type zinc finger containing 1 [Source:MGI Symbol;Acc:MGI:1344372])

HSP 1 Score: 37.7354 bits (86), Expect = 3.718e-7
Identity = 28/98 (28.57%), Postives = 50/98 (51.02%), Query Frame = 2 
Query:  848 FCCKYESCSG--FWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            + CK   C G  F++ +  N F  C  C  +NCL C+ IHE+M+C +++          +  + +N+ + +      KV++Q G   ++HCP C + V
Sbjct:  367 YHCKTPDCRGWCFFE-DDVNEF-TCPVCTRVNCLLCKAIHEHMNCREYQDD--------LALRAQNDVAARQTTEMLKVMLQQG--EAMHCPQCRIVV 452

HSP 2 Score: 36.5798 bits (83), Expect = 3.718e-7
Identity = 19/64 (29.69%), Postives = 32/64 (50.00%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  +CP       C   + ER+I  L
Sbjct:  280 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVACPFIDSTYSCPGKLLEREIRAL 342
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Match: sp|E6ZIJ1|HOIL1_DICLA (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Dicentrarchus labrax OX=13489 GN=rbck1 PE=3 SV=1)

HSP 1 Score: 44.669 bits (104), Expect = 5.451e-9
Identity = 31/100 (31.00%), Postives = 54/100 (54.00%), Query Frame = 3 
Query:  540 EFLKSRNKEQLKSF---ILKD--EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
            ++ ++R +E+ ++F   ++ D  + +PNP+   C IC   + P EG++LR C H +C+EC    +++V  LS     SCP       C   + ER+I  L
Sbjct:  446 QYQQAREEERRENFARLVMMDSQDLLPNPEPVDCRICYMDLQPGEGVLLRECLHCFCREC----LRSVIMLSEEPEVSCPYRDDTYSCACSLQEREIRAL 541

HSP 2 Score: 38.5058 bits (88), Expect = 5.451e-9
Identity = 27/80 (33.75%), Postives = 41/80 (51.25%), Query Frame = 2 
Query:  890 NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHV 1129
            +  N FH C  C   NCL C+ IHE M+C  ++     L A+ +        + + L  K L+Q+G   ++HCP CG+ V
Sbjct:  581 DTVNVFH-CPVCRKHNCLICKSIHEGMNCKQYQDD---LAARAINDSAARR-TTQLL--KTLVQSG--EAMHCPQCGIIV 651
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Match: sp|A9JTG5|HOIL1_DANRE (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Danio rerio OX=7955 GN=rbck1 PE=2 SV=1)

HSP 1 Score: 40.817 bits (94), Expect = 2.621e-7
Identity = 28/100 (28.00%), Postives = 52/100 (52.00%), Query Frame = 3 
Query:  540 EFLKSRNKEQLKSF-----ILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
            ++ ++R  E+ ++F     +   + +PNP+   C IC   +   EG++LR C H +CKEC    +++V  +S   + +CP       C+  + ER+I  L
Sbjct:  453 QYQQARETERRENFARLVQMDGQDLVPNPERVECRICYVELESGEGVLLRECLHCFCKEC----LRSVILMSEDPQVACPYRDESYACDCVLQEREIRAL 548

HSP 2 Score: 36.5798 bits (83), Expect = 2.621e-7
Identity = 31/101 (30.69%), Postives = 48/101 (47.52%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            E  + C    C G W +  +  N FH C  C   NCL C+ IHE M+C  ++     L A+ +     N+ + +      K L+ +G   ++HCP CG+ V
Sbjct:  570 EGSYHCATADCPG-WCVYEDTVNTFH-CPVCKKQNCLLCKAIHEGMNCKQYQDD---LTARAI-----NDSAARRTRDLLKTLVNSG--EAMHCPQCGIIV 658
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9BYM8|HOIL1_HUMAN (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=RBCK1 PE=1 SV=2)

HSP 1 Score: 38.891 bits (89), Expect = 2.775e-7
Identity = 28/109 (25.69%), Postives = 52/109 (47.71%), Query Frame = 2 
Query:  848 FCCKYESCSGF-WDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKK---------PQYLEAKLVK*KLKNNPSVKCLCGKVLIQ-NGGCGSLHCPNCGVHVCVFT 1141
            + CK   C G+ +  +  N F  C  C H+NCL C+ IHE M+C ++++                +++K  L+   +++C   ++++Q   GC  + C  C   +C  T
Sbjct:  369 YHCKTPDCKGWCFFEDDVNEF-TCPVCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVT 476

HSP 2 Score: 38.5058 bits (88), Expect = 2.775e-7
Identity = 20/64 (31.25%), Postives = 33/64 (51.56%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  SCP       C+  + ER+I  L
Sbjct:  282 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVSCPFIDNTYSCSGKLLEREIKAL 344
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q9WUB0|HOIL1_MOUSE (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Mus musculus OX=10090 GN=Rbck1 PE=1 SV=2)

HSP 1 Score: 37.7354 bits (86), Expect = 2.252e-6
Identity = 28/98 (28.57%), Postives = 50/98 (51.02%), Query Frame = 2 
Query:  848 FCCKYESCSG--FWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            + CK   C G  F++ +  N F  C  C  +NCL C+ IHE+M+C +++          +  + +N+ + +      KV++Q G   ++HCP C + V
Sbjct:  367 YHCKTPDCRGWCFFE-DDVNEF-TCPVCTRVNCLLCKAIHEHMNCREYQDD--------LALRAQNDVAARQTTEMLKVMLQQG--EAMHCPQCRIVV 452

HSP 2 Score: 36.5798 bits (83), Expect = 2.252e-6
Identity = 19/64 (29.69%), Postives = 32/64 (50.00%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            C +C   + P E ++LR C H +C+EC    ++N +  +  +CP       C   + ER+I  L
Sbjct:  280 CPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVACPFIDSTYSCPGKLLEREIRAL 342
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Match: sp|Q62921|HOIL1_RAT (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Rbck1 PE=1 SV=3)

HSP 1 Score: 37.7354 bits (86), Expect = 3.611e-6
Identity = 21/70 (30.00%), Postives = 34/70 (48.57%), Query Frame = 3 
Query:  606 NPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLL 797
            N +   C +C   + P E ++LR C H +C+EC    ++N +  +  SCP       C   + ER+I  L
Sbjct:  274 NTEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQE-AEVSCPFIDNTYSCPGKLLEREIRAL 342

HSP 2 Score: 35.8094 bits (81), Expect = 3.611e-6
Identity = 27/96 (28.12%), Postives = 48/96 (50.00%), Query Frame = 2 
Query:  848 FCCKYESCSG--FWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHV 1129
            + CK   C G  F++ +  N F  C  C  +NCL C+ IHE M+C +++       A   +  +    + + L  +V++Q G   +++CP C + V
Sbjct:  367 YHCKTPDCRGWCFFE-DDVNEF-TCPVCTRVNCLLCKAIHERMNCREYQDD----LAHRARNDVAAQQTTEML--RVMLQQG--EAMYCPQCRIVV 452
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Match: A0A182F5I7 (Uncharacterized protein OS=Anopheles albimanus OX=7167 PE=4 SV=1)

HSP 1 Score: 50.447 bits (119), Expect = 7.096e-11
Identity = 35/126 (27.78%), Postives = 54/126 (42.86%), Query Frame = 3 
Query:  456 CFKCNKRHCPVDCGRNNSN--EDLIDISATEFLKSRNKEQLKSFILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLLA*KK 809
            C    ++  PV  GRN     ED  ++    + +  N +         + I N + F C IC     P EG++LR+C H +CK+C I  +Q     +   CP       C   I +R+I  L  K+
Sbjct: 1702 CPADQQQQAPVRFGRNGLALPEDGAEVMQNHYTELVNLDNA-------DLIANIEPFECPICFGSFQPYEGIVLRDCLHSFCKQCLISTIQYSD-EAEIRCPYSDAVYSCESVIQQREIKALVSKE 1819

HSP 2 Score: 46.9802 bits (110), Expect = 7.096e-11
Identity = 31/110 (28.18%), Postives = 50/110 (45.45%), Query Frame = 2 
Query:  848 FCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQY-----LEAKLVK*KLK----NNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            F C+  +C G W I  +  N F +C  C  +NCL C  IH+ + C  ++ +        LEA+  K  L+       ++ C  C  ++++  GC  L C  C   +C  T
Sbjct: 1840 FHCRTPNCRG-WCIFEDNVNQF-KCPVCTIVNCLTCRVIHDGLDCKQYQDRMNSDCDTNLEARRTKAMLQEMIEKGDALNCPTCQVIVMKKWGCDWLKCSMCKTEICWVT 1947
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Match: A0A182Q1P1 (Uncharacterized protein OS=Anopheles farauti OX=69004 PE=4 SV=1)

HSP 1 Score: 50.0618 bits (118), Expect = 1.125e-10
Identity = 26/78 (33.33%), Postives = 39/78 (50.00%), Query Frame = 3 
Query:  594 EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLLA*KK 809
            + I N + F C IC     P EG++LR+C H +CK+C I  +Q  +  +   CP       C   I +R+I  L  K+
Sbjct: 1778 DLIANIEPFECPICFGAFQPYEGIVLRDCLHSFCKQCLISTIQYSED-AEIRCPYSDAVYSCESVIQQREIKALVSKE 1854

HSP 2 Score: 46.9802 bits (110), Expect = 1.125e-10
Identity = 31/110 (28.18%), Postives = 50/110 (45.45%), Query Frame = 2 
Query:  848 FCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQY-----LEAKLVK*KLK----NNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            F C+  +C G W I  +  N F +C  C  +NCL C  IH+ + C  ++ +        LEA+  K  L+       ++ C  C  ++++  GC  L C  C   +C  T
Sbjct: 1875 FHCRTPNCRG-WCIFEDNVNQF-KCPVCRIVNCLTCRVIHDGLDCKQYQDRMNSDCDTNLEARRTKAMLQEMIEKGEALNCPTCQVIVMKKWGCDWLKCSMCKTEICWVT 1982
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Match: A0A182NEW1 (Uncharacterized protein OS=Anopheles dirus OX=7168 PE=4 SV=1)

HSP 1 Score: 50.0618 bits (118), Expect = 1.221e-10
Identity = 26/78 (33.33%), Postives = 39/78 (50.00%), Query Frame = 3 
Query:  594 EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLLA*KK 809
            + I N + F C IC     P EG++LR+C H +CK+C I  +Q  +  +   CP       C   I +R+I  L  K+
Sbjct: 1780 DLIANIEPFECPICFGAFQPYEGIVLRDCLHSFCKQCLISTIQYSED-AEIRCPYSDAVYSCESVIQQREIKALVSKE 1856

HSP 2 Score: 46.9802 bits (110), Expect = 1.221e-10
Identity = 31/110 (28.18%), Postives = 50/110 (45.45%), Query Frame = 2 
Query:  848 FCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQY-----LEAKLVK*KLK----NNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            F C+  +C G W I  +  N F +C  C  +NCL C  IH+ + C  ++ +        LEA+  K  L+       ++ C  C  ++++  GC  L C  C   +C  T
Sbjct: 1877 FHCRTPNCRG-WCIFEDNVNQF-KCPVCRIVNCLTCRVIHDGLDCKQYQDRMNSDCDTNLEARRTKAMLQEMIEKGEALNCPTCQVIVMKKWGCDWLKCSMCKTEICWVT 1984
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Match: A0A3Q0JE52 (LOW QUALITY PROTEIN: uncharacterized protein LOC103517347 OS=Diaphorina citri OX=121845 GN=LOC103517347 PE=4 SV=1)

HSP 1 Score: 53.5286 bits (127), Expect = 1.382e-10
Identity = 32/116 (27.59%), Postives = 53/116 (45.69%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI-NKANGFHQCSSCGHLNCLECEDIHENMSCNDFR-------------KKPQYLEAKLVK*KLKNNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            E  F CK   C G+    ++ N FH C  C H NCL C+ IH+ ++C  ++             +K Q +  ++    L+   ++KC  C  ++++  GC  L C  C   +C  T
Sbjct: 3987 ENAFHCKTPDCQGWCTFEDEVNEFH-CPVCWHCNCLTCQAIHDELNCKQYQDHLKEVAKTNEDARKTQEMLDRM----LERREAMKCPRCEVLVMKKSGCDWLRCSMCKTEICWVT 4097

HSP 2 Score: 42.743 bits (99), Expect = 1.382e-10
Identity = 26/101 (25.74%), Postives = 45/101 (44.55%), Query Frame = 3 
Query:  510 NEDLIDISATEFLKSRNKEQLKSFIL--KDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKD------IHERDI 788
            NE   ++   +  +++ +   K  +L  K E + N + F C IC     P  G +LR C H +CK+C    ++     +   CP  + D      I +R+I
Sbjct: 3863 NEIRTEVQVDQKTQAQKEANYKELVLLEKAELVLNIETFECPICFTECTPSNGAVLRECLHSFCKQCLSHLIEYSD-EAEVKCPYVDNDYSCSCLIRDREI 3962
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Match: A0A1S4H1B2 (RanBP-type and C3HC4-type zinc finger-containing protein 1 OS=Anopheles gambiae OX=7165 PE=4 SV=1)

HSP 1 Score: 49.2914 bits (116), Expect = 1.624e-10
Identity = 26/78 (33.33%), Postives = 39/78 (50.00%), Query Frame = 3 
Query:  594 EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP------RCNKDIHERDIFLLA*KK 809
            + I N + F C IC     P EG++LR+C H +CK+C I  +Q  +  +   CP       C   I +R+I  L  K+
Sbjct: 1785 DLIANIEPFECPICFGAFQPYEGIVLRDCLHSFCKQCLISTIQYSED-AAIRCPYSDAVYSCESVIQQREIKALVSKE 1861

HSP 2 Score: 46.9802 bits (110), Expect = 1.624e-10
Identity = 31/110 (28.18%), Postives = 50/110 (45.45%), Query Frame = 2 
Query:  848 FCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQY-----LEAKLVK*KLK----NNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            F C+  +C G W I  +  N F +C  C  +NCL C  IH+ + C  ++ +        LEA+  K  L+       ++ C  C  ++++  GC  L C  C   +C  T
Sbjct: 1882 FHCRTPNCRG-WCIYEDNVNQF-KCPVCRIVNCLTCRVIHDGLDCKQYQDRMNSDCDTNLEARRTKAMLQEMIEKGEALNCPTCQVIVMKKWGCDWLKCSMCKTEICWVT 1989
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Cavefish
Match: shrprbck1r (ranBP-type and C3HC4-type zinc finger-containing protein 1-like [Source:NCBI gene;Acc:103029459])

HSP 1 Score: 43.8986 bits (102), Expect = 2.611e-9
Identity = 27/78 (34.62%), Postives = 42/78 (53.85%), Query Frame = 3 
Query:  591 DEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
             E +PNP+   C IC   + P EG++LR C H +C+EC    +++V  LS   + +CP       C+  + ER+I  L
Sbjct:  457 QELVPNPESVECRICYLQLQPGEGVLLRECLHCFCREC----LRSVILLSEDPQVACPYRDEAYACDCVLQEREIRAL 530

HSP 2 Score: 37.7354 bits (86), Expect = 2.611e-9
Identity = 31/101 (30.69%), Postives = 49/101 (48.51%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            E  + C    C G W +  +  N FH C  C   NCL C+ IHE M+C  ++     L A+ +     N+ + +      K L+++G   ++HCP CG+ V
Sbjct:  552 EGSYHCATTDCPG-WCVYEDTVNTFH-CPVCTKHNCLLCKAIHEGMNCKQYQDD---LAARAI-----NDTAARRTRDLLKTLVRSG--EAMHCPQCGIIV 640
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Cavefish
Match: shrprbck1r (ranBP-type and C3HC4-type zinc finger-containing protein 1-like [Source:NCBI gene;Acc:103029459])

HSP 1 Score: 43.8986 bits (102), Expect = 2.650e-9
Identity = 27/78 (34.62%), Postives = 42/78 (53.85%), Query Frame = 3 
Query:  591 DEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
             E +PNP+   C IC   + P EG++LR C H +C+EC    +++V  LS   + +CP       C+  + ER+I  L
Sbjct:  486 QELVPNPESVECRICYLQLQPGEGVLLRECLHCFCREC----LRSVILLSEDPQVACPYRDEAYACDCVLQEREIRAL 559

HSP 2 Score: 37.7354 bits (86), Expect = 2.650e-9
Identity = 31/101 (30.69%), Postives = 49/101 (48.51%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCG--KVLIQNGGCGSLHCPNCGVHV 1129
            E  + C    C G W +  +  N FH C  C   NCL C+ IHE M+C  ++     L A+ +     N+ + +      K L+++G   ++HCP CG+ V
Sbjct:  581 EGSYHCATTDCPG-WCVYEDTVNTFH-CPVCTKHNCLLCKAIHEGMNCKQYQDD---LAARAI-----NDTAARRTRDLLKTLVRSG--EAMHCPQCGIIV 669
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Cavefish
Match: shrprbck1r (ranBP-type and C3HC4-type zinc finger-containing protein 1-like [Source:NCBI gene;Acc:103029459])

HSP 1 Score: 43.5134 bits (101), Expect = 3.908e-7
Identity = 27/78 (34.62%), Postives = 42/78 (53.85%), Query Frame = 3 
Query:  591 DEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
             E +PNP+   C IC   + P EG++LR C H +C+EC    +++V  LS   + +CP       C+  + ER+I  L
Sbjct:  486 QELVPNPESVECRICYLQLQPGEGVLLRECLHCFCREC----LRSVILLSEDPQVACPYRDEAYACDCVLQEREIRAL 559

HSP 2 Score: 30.4166 bits (67), Expect = 3.908e-7
Identity = 19/52 (36.54%), Postives = 26/52 (50.00%), Query Frame = 2 
Query:  839 EKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSCNDFR 988
            E  + C    C G W +  +  N FH C  C   NCL C+ IHE M+C  ++
Sbjct:  581 EGSYHCATTDCPG-WCVYEDTVNTFH-CPVCTKHNCLLCKAIHEGMNCKQYQ 630
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Sea Lamprey
Match: RBCK1 (RANBP2-type and C3HC4-type zinc finger containing 1 [Source:HGNC Symbol;Acc:HGNC:15864])

HSP 1 Score: 47.3654 bits (111), Expect = 4.496e-10
Identity = 37/142 (26.06%), Postives = 68/142 (47.89%), Query Frame = 3 
Query:  405 FENVELVILCEIC--CQPNCFKCNKRHCPVDCGRNNSNEDLIDISATEFLK-SRNKEQLKSFILKDE--FIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKDI------HERDIFLL 797
            F N+ L   C+ C   +P  ++    + P D  R  +++++ +    E  +  + +E  +  + +DE   +PN + F C IC     P EG+ LR C H +CK+C    + N +  +  +CP  + +I      H+R+I  L
Sbjct:  214 FVNLPLRPGCDQCGTARPADYQVPAGYQPTDRERRITDQEMDNRRKLEETRVKKRRENFQRLMQEDEQELVPNKEAFTCPICFVDYEPGEGVTLRECLHNFCKDCLHGTIVNCED-AEVTCPNQDGEISCEFKLHQREIKAL 354

HSP 2 Score: 34.2686 bits (77), Expect = 4.496e-10
Identity = 28/104 (26.92%), Postives = 48/104 (46.15%), Query Frame = 2 
Query:  818 IYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHV 1129
            I  ++ A+ Y C   +     +  +  N F  C  C   NCL C+ IHE M C +++   + L +   +  ++ N     L  + ++Q G   ++HCP C V V
Sbjct:  370 IAENRSADSYHCVTADCLGWCFYEDMVNDFL-CPICKKSNCLTCKAIHEGMDCQEYQDDLK-LRSDNDQAAMQTN-----LMLQTMVQTG--DAMHCPTCKVIV 464
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Medaka
Match: rbck1 (ranBP-type and C3HC4-type zinc finger-containing protein 1 [Source:NCBI gene;Acc:101166217])

HSP 1 Score: 41.5874 bits (96), Expect = 2.287e-9
Identity = 21/56 (37.50%), Postives = 33/56 (58.93%), Query Frame = 3 
Query:  624 CEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCP-RCNKDIHERDI 788
            C IC + + P EG++LR C H +C+EC I  ++N    +  SCP  C   + +R+I
Sbjct:  295 CPICFNALQPGEGVVLRECLHTFCRECLIGTIRNSNN-AEVSCPDDCESKLLDREI 349

HSP 2 Score: 40.0466 bits (92), Expect = 2.287e-9
Identity = 34/116 (29.31%), Postives = 59/116 (50.86%), Query Frame = 2 
Query:  836 AEKYFCCKYESCSGFWDI--NKANGFHQCSSCGHLNCLECEDIHENMSC----NDFRKKPQYLEA-----KLVK*KLKNNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFTGK 1147
            +E  F C+  +C G W I  ++ N FH C  C  +NCL C  IH++M+C    +D R + Q  +A     ++++  L+N  ++ C  C  ++ +  GC  + C  C   +C  T +
Sbjct:  373 SEHSFHCQTPNCRG-WCIYEDEVNEFH-CDLCLEVNCLLCRAIHKDMNCKDYQDDLRIRAQNDKAAQQTKQMLESMLQNGEAMNCPRCAIIVQKKDGCDWICCLMCKTEICWVTKQ 486
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Medaka
Match: shrprbck1r (ranBP-type and C3HC4-type zinc finger-containing protein 1 [Source:NCBI gene;Acc:101169745])

HSP 1 Score: 45.0542 bits (105), Expect = 1.378e-8
Identity = 32/103 (31.07%), Postives = 55/103 (53.40%), Query Frame = 3 
Query:  531 SATEFLKSRNKEQLKSF---ILKD--EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLS---RFSCP------RCNKDIHERDIFLL 797
            S  ++ ++R KE+ ++F   ++ D  + +PNPD   C IC   +   +G++LR C H +C+EC    +++V  LS     SCP       C+  + ER+I  L
Sbjct:  445 SIRQYQQAREKERRENFARLVMMDGQDLVPNPDPVDCRICYMDLPSGQGVLLRECLHCFCREC----LRSVIMLSEEPEVSCPYRDDAYSCDGVLQEREIKAL 543

HSP 2 Score: 33.8834 bits (76), Expect = 1.378e-8
Identity = 27/98 (27.55%), Postives = 44/98 (44.90%), Query Frame = 2 
Query:  890 NKANGFHQCSSCGHLNCLECEDIHENMSCNDFR-------------KKPQYLEAKLVK*KLKNNPSVKC-LCGKVLIQNGGCGSLHCPNCGVHVCVFT 1141
            +  N FH C  C   NCL C+ IHE M+C  ++             ++  +L   LV    ++  ++ C  CG ++ +  GC  L C  C + +C  T
Sbjct:  583 DTVNVFH-CPVCRKHNCLICKAIHEGMNCKQYQDDLAVRAINDSAARRTTHLLMTLV----QSGEAMYCPQCGIIVQKRDGCDWLRCTVCHIEICWVT 675
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Match: SMESG000079849.1 (SMESG000079849.1)

HSP 1 Score: 363.229 bits (931), Expect = 1.288e-167
Identity = 196/197 (99.49%), Postives = 196/197 (99.49%), Query Frame = 3 
Query:  201 ECLCNYIEMNXXXXXXXXXXXXXXYISDRIIRQCLSNCNIEIYENSSILATHPGARKCLTKNCPKYFYFENVELVILCEICCQPNCFKCNKRHCPVDCGRNNSNEDLIDISATEFLKSRNKEQLKSFILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKDIHERDIF 791
            ECLCNYIEMNIICKIKCPIKECRKYISDRIIRQCLSNCNIEIYENSSILATHPGARKCLTKNCPKYFYFENVELVILCEICCQPNCFKCNKRHCPVDCGRNNSNEDLIDISATEFLKSRNKEQLKSFILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKDIHERDI 
Sbjct:    6 ECLCNYIEMNIICKIKCPIKECRKYISDRIIRQCLSNCNIEIYENSSILATHPGARKCLTKNCPKYFYFENVELVILCEICCQPNCFKCNKRHCPVDCGRNNSNEDLIDISATEFLKSRNKEQLKSFILKDEFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKDIHERDIL 202

HSP 2 Score: 247.284 bits (630), Expect = 1.288e-167
Identity = 122/129 (94.57%), Postives = 123/129 (95.35%), Query Frame = 2 
Query:  770 YSRKGYISIGIEKITHIYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHVCVFTGKIAG 1156
            + R    SIGIEKITHIYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK KLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHVCVFTGKIAG
Sbjct:  197 HERDILYSIGIEKITHIYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVKEKLKNNPSVKCLCGKVLIQNGGCGSLHCPNCGVHVCVFTGKIAG 325
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Match: SMESG000079844.1 (SMESG000079844.1)

HSP 1 Score: 164.081 bits (414), Expect = 1.173e-66
Identity = 101/197 (51.27%), Postives = 134/197 (68.02%), Query Frame = 3 
Query:  201 ECLCNYIEMNXXXXXXXXXXXXXXYISDRIIRQCLSNCNIEIYENSSILATHPGARKCLTKNCPKYFYFENVELVILCEICCQPNCFKCNKRHCPVDCGRNNSNEDLIDISATEFLKSRNKEQLKSFILKD-EFIPNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSCPRCNKDIHERDI 788
            ECLC YIE+ I   IKCPI      ISD+IIR+CLSN +I  YE+  I +++P ARKCLT+NC      EN  ++  C+ C QPNC KC KRH P  CG N S ED I+I+ATE +K + +++LK   L D   IPNPD F C +C+ FILPREGLI RNC+H +CK CF EAM+NV  ++ F CP+C ++++ ++I
Sbjct:   31 ECLCKYIEVKIDKIIKCPICPGN--ISDQIIRRCLSNADIRKYESICINSSNPKARKCLTQNCHMIKVIENDNVIYHCDYCNQPNCLKCKKRHYPNQCGLNIS-EDNINIAATEAIKIKKQKELKE--LGDLNIIPNPDKFECCLCNSFILPREGLITRNCHHTFCKSCFNEAMKNVTLINNFKCPQCEQNLNHQEI 222

HSP 2 Score: 109.383 bits (272), Expect = 1.173e-66
Identity = 56/123 (45.53%), Postives = 76/123 (61.79%), Query Frame = 2 
Query:  794 IGIEKITHIYTSQVAEKYFCCKYESCSGFWDINKANGFHQCSSCGHLNCLECEDIHENMSCNDFRKKPQYLEAKLVK*KLKNNP-SVKCLCGKVL-IQNGGCGSLHCPNCGVHVCVFTGKIAG 1156
            I +   + +    VA K FCCK+ +C G WD N  NGF+ C  C H NCLEC+ +HE+ SC  +R    Y +++  K KL+     VKCLCG +L I  GGCG+++C +CG  VC FTGK+AG
Sbjct:  226 IDLPDFSTLNCKPVAPKMFCCKFPNCEGMWDKNNVNGFYVCPVCKHKNCLECDGVHESQSCEKYRNSKMYKQSQEAKLKLQETVGRVKCLCGAMLTIAPGGCGAIYCTSCGRQVCQFTGKLAG 348
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Match: SMESG000036578.1 (SMESG000036578.1)

HSP 1 Score: 163.696 bits (413), Expect = 1.119e-47
Identity = 93/139 (66.91%), Postives = 102/139 (73.38%), Query Frame = 1 
Query: 1180 SQQFPILQRELDKAQGANRDLHQQLLQLTGEIQQIKGTWIELKRAKVVYQRMEAAQKGLAGERQLTQNLKTQIKGLETALSASQEGAAVIYPLVFTPRNWLIETR*FRQHPRTNPTGTSQEEPSAQNVG----GSRRRM 1584
            S QF +LQ ELDKAQ AN+DLHQQL+QLT EIQQIKGTWIE KRAKVVYQRMEAAQK  AG+RQLTQNLKTQIKGL+TALSASQEGAAV YPLVF P                NPT TS+++PS    G      RRR+
Sbjct:   11 SPQFSMLQLELDKAQAANQDLHQQLIQLTREIQQIKGTWIEPKRAKVVYQRMEAAQKEWAGKRQLTQNLKTQIKGLKTALSASQEGAAVTYPLVFAPAQ-------LAYRDTINPT-TSKDKPSRHRPGKAECAKRRRL 141
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Match: SMESG000025415.1 (SMESG000025415.1)

HSP 1 Score: 156.377 bits (394), Expect = 1.733e-44
Identity = 91/137 (66.42%), Postives = 97/137 (70.80%), Query Frame = 1 
Query: 1174 MKSQQFPILQRELDKAQGANRDLHQQLLQLTGEIQQIKGTWIELKRAKVVYQRMEAAQKGLAGERQLTQNLKTQIKGLETALSASQEGAAVIYPLVFTPRNWLIETR*FRQHPRTNPTGTSQEEPSAQNVGGSRRRM 1584
            M SQQFPILQRELDKAQ ANRDL QQL+QLT EIQ IKGTWIE KRAKVVYQRMEAAQ+  A ERQL QNL+TQIKGLETALSASQEGAAV Y                  HPRT P   +Q  PS   V  S++RM
Sbjct:    1 MNSQQFPILQRELDKAQTANRDLQQQLIQLTREIQLIKGTWIEPKRAKVVYQRMEAAQREWAAERQLVQNLRTQIKGLETALSASQEGAAVTYGSNSD------------DHPRTVPATYNQPGPSP-TVIASQQRM 124
[Close]
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Match: SMESG000031748.1 (SMESG000031748.1)

HSP 1 Score: 163.31 bits (412), Expect = 4.996e-42
Identity = 86/136 (63.24%), Postives = 96/136 (70.59%), Query Frame = 1 
Query: 1171 QMKSQQFPILQRELDKAQGANRDLHQQLLQLTGEIQQIKGTWIELKRAKVVYQRMEAAQKGLAGERQLTQNLKTQIKGLETALSASQEGAAVIYPLVFTPRNWLIETR*FRQHPRTNPTGTSQEEPSAQNVGGSRR 1578
            +M SQQ P LQRELDKA   NRDLH QLLQLT EI QIKGTW+E KR KVVYQR+EAAQKG AGERQL QNL+TQIKGLETALS SQEGAAV YPLVF P            +  T    TS+++P+    G + R
Sbjct: 1254 EMNSQQLPALQRELDKAHATNRDLHHQLLQLTREIPQIKGTWMEPKRVKVVYQRLEAAQKGWAGERQLVQNLRTQIKGLETALSVSQEGAAVTYPLVFAPAQL--------AYRDTLDPSTSKDKPNRHRPGKAER 1381
The following BLAST results are available for this feature:
BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
RBCK16.329e-825.69RANBP2-type and C3HC4-type zinc finger containing ... [more]
RBCK17.228e-824.07RANBP2-type and C3HC4-type zinc finger containing ... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
shrprbck1r4.238e-828.00sharpin and rbck1 related [Source:NCBI gene;Acc:56... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSXETT00000033448.12.615e-623.39RanBP-type and C3HC4-type zinc finger containing 1... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Rbck13.718e-728.57RanBP-type and C3HC4-type zinc finger containing 1... [more]
Rbck13.718e-728.57RanBP-type and C3HC4-type zinc finger containing 1... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|E6ZIJ1|HOIL1_DICLA5.451e-931.00RanBP-type and C3HC4-type zinc finger-containing p... [more]
sp|A9JTG5|HOIL1_DANRE2.621e-728.00RanBP-type and C3HC4-type zinc finger-containing p... [more]
sp|Q9BYM8|HOIL1_HUMAN2.775e-725.69RanBP-type and C3HC4-type zinc finger-containing p... [more]
sp|Q9WUB0|HOIL1_MOUSE2.252e-628.57RanBP-type and C3HC4-type zinc finger-containing p... [more]
sp|Q62921|HOIL1_RAT3.611e-630.00RanBP-type and C3HC4-type zinc finger-containing p... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A182F5I77.096e-1127.78Uncharacterized protein OS=Anopheles albimanus OX=... [more]
A0A182Q1P11.125e-1033.33Uncharacterized protein OS=Anopheles farauti OX=69... [more]
A0A182NEW11.221e-1033.33Uncharacterized protein OS=Anopheles dirus OX=7168... [more]
A0A3Q0JE521.382e-1027.59LOW QUALITY PROTEIN: uncharacterized protein LOC10... [more]
A0A1S4H1B21.624e-1033.33RanBP-type and C3HC4-type zinc finger-containing p... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
shrprbck1r2.611e-934.62ranBP-type and C3HC4-type zinc finger-containing p... [more]
shrprbck1r2.650e-934.62ranBP-type and C3HC4-type zinc finger-containing p... [more]
shrprbck1r3.908e-734.62ranBP-type and C3HC4-type zinc finger-containing p... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
RBCK14.496e-1026.06RANBP2-type and C3HC4-type zinc finger containing ... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
rbck12.287e-937.50ranBP-type and C3HC4-type zinc finger-containing p... [more]
shrprbck1r1.378e-831.07ranBP-type and C3HC4-type zinc finger-containing p... [more]
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BLAST of RanBP-type and C3HC4-type zinc finger-containing protein 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000079849.11.288e-16799.49SMESG000079849.1[more]
SMESG000079844.11.173e-6651.27SMESG000079844.1[more]
SMESG000036578.11.119e-4766.91SMESG000036578.1[more]
SMESG000025415.11.733e-4466.42SMESG000025415.1[more]
SMESG000031748.14.996e-4263.24SMESG000031748.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024723 ID=SMED30024723|Name=RanBP-type and C3HC4-type zinc finger-containing protein 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1756bp
CTGGCCTTGAATATTTTGAAACTATTCCAATTTTTAAAAGATCTCTATTT
TTATTATTAGTTACATATTTTAAATGTTTATCAAATATTTGCATTTCTAT
ATTCAGAAAATACAATAATTCAAAAGAAAATTCAAAATGTCAGTATGTCA
AAAGTGTAATGAGATTAAAAAATCTATTACTTTTCGATCATGTCAACATT
GAATGTTTGTGTAATTATATCGAAATGAATATTATTTGTAAAATAAAATG
TCCTATAAAAGAATGTCGTAAATATATTTCTGATCGCATAATAAGACAAT
GTTTATCAAATTGTAACATAGAAATCTATGAAAATTCTTCAATTTTAGCC
ACTCATCCCGGCGCCAGGAAGTGTTTGACAAAAAATTGTCCTAAATATTT
TTATTTCGAAAACGTCGAATTGGTAATTTTGTGTGAAATTTGCTGCCAGC
CGAATTGTTTTAAATGCAACAAACGACATTGCCCAGTCGATTGTGGGCGG
AATAATTCAAATGAAGATTTAATTGATATCTCAGCAACTGAATTTCTTAA
ATCTCGGAATAAAGAACAGTTAAAAAGTTTTATTTTAAAAGACGAGTTTA
TTCCAAATCCTGATCATTTTATATGCGAAATCTGTGATGACTTTATTTTG
CCAAGGGAAGGATTAATTCTGAGGAATTGTTATCATCCATATTGCAAGGA
ATGTTTTATAGAAGCAATGCAGAATGTTAAATTTCTTTCAAGATTTAGTT
GCCCACGGTGTAATAAAGATATTCACGAAAGGGATATATTTCTATTGGCA
TAGAAAAAATAACACATATCTATACATCGCAAGTTGCGGAGAAATACTTT
TGTTGTAAATATGAAAGTTGTTCAGGTTTCTGGGATATCAATAAGGCTAA
TGGATTCCATCAATGTTCCTCATGTGGTCATTTAAACTGTTTGGAGTGTG
AAGATATACATGAAAATATGTCTTGTAATGATTTCAGAAAAAAACCTCAA
TATCTGGAAGCAAAATTGGTCAAATAAAAATTGAAGAACAATCCTTCTGT
AAAATGTTTATGTGGTAAGGTTCTTATACAAAATGGAGGATGTGGATCAC
TGCATTGTCCTAATTGTGGAGTTCATGTTTGTGTGTTTACGGGCAAAATT
GCTGGAAATAGAGAACCAAACAGATGAAGTCCCAACAATTCCCCATTCTA
CAAAGGGAATTAGATAAGGCCCAGGGAGCCAACCGGGATTTACATCAACA
GCTACTCCAACTCACCGGAGAGATCCAGCAGATCAAGGGCACCTGGATCG
AACTGAAAAGGGCGAAGGTTGTTTACCAAAGAATGGAAGCAGCGCAAAAA
GGGTTGGCCGGCGAGCGACAATTGACGCAGAACTTGAAGACTCAAATTAA
AGGGCTAGAAACAGCACTGTCGGCGAGTCAAGAAGGGGCAGCAGTAATTT
ACCCGTTGGTCTTCACCCCGCGCAATTGGCTTATCGAAACACGATAGTTC
CGACAACACCCAAGGACAAACCCAACCGGCACCAGCCAGGAAGAGCCGAG
CGCGCAAAACGTCGGCGGCTCAAGGAGGCGAATGTGATTTAATTCATGAA
CATAAATTTTTCTTTTAATAAATGATATCATTGATAGTTCGTATTGTTAA
CTGACCCAACTCAATTGACTAATTCGAAGTGCAAACCTGGAAAATCTCAA
TAACGAAAAATTACTTTTAGTAAAGGACCCAAATAAATTTGATTCGAGCA
CAGGCC
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protein sequence of SMED30024723-orf-1

>SMED30024723-orf-1 ID=SMED30024723-orf-1|Name=SMED30024723-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=267bp
GLEYFETIPIFKRSLFLLLVTYFKCLSNICISIFRKYNNSKENSKCQYVK
SVMRLKNLLLFDHVNIECLCNYIEMNIICKIKCPIKECRKYISDRIIRQC
LSNCNIEIYENSSILATHPGARKCLTKNCPKYFYFENVELVILCEICCQP
NCFKCNKRHCPVDCGRNNSNEDLIDISATEFLKSRNKEQLKSFILKDEFI
PNPDHFICEICDDFILPREGLILRNCYHPYCKECFIEAMQNVKFLSRFSC
PRCNKDIHERDIFLLA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: INTERPRO
TermDefinition
IPR001841Znf_RING
IPR013083Znf_RING/FYVE/PHD
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0008270zinc ion binding
GO:0046872metal ion binding