inositol 1,4,5-trisphosphate receptor type 3 isoform X13

Overview
Nameinositol 1,4,5-trisphosphate receptor type 3 isoform X13
Smed IDSMED30024629
Length (bp)8317
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 (SMED30024629) t-SNE clustered cells

Violin plots show distribution of expression levels for inositol 1,4,5-trisphosphate receptor type 3 isoform X13 (SMED30024629) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 (SMED30024629) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for inositol 1,4,5-trisphosphate receptor type 3 isoform X13 (SMED30024629) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30024629

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30024629h1SMcG0004941 SmedASXL_017391SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
pharynxSMED30024629h1SMcG0004941 dd_Smed_v4_13538_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
protonephridiaSMED30024629h1SMcG0004941 dd_Smed_v4_13538_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 128.257 bits (321), Expect = 2.073e-28
Identity = 251/1162 (21.60%), Postives = 469/1162 (40.36%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKN-------DKKFRSSFNKGFTMMER----DELQ--------DFHYRSRFEVSECNNV-----------IVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK--------DTRAAVMVNQDQRKQTDFMAQLFQENFD--INNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDM-MITHGKDSDSWLKMIQDF 3231
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD  +        K  +   NKG  +M       EL          F   +    +   NV           ++D K   +E+L+ +L  +L+ R   L+ +FK         T      N  Q   ++    L  E+ +     I   S+E     T L       + F       VLL LT + Y  L+  +L  + + FS ++ V      + ++   +D D++ ++ QD 
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEE----NTPLDLDDHGGRTF-----LRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDL 1105          

HSP 2 Score: 74.3294 bits (181), Expect = 4.007e-12
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2574 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2667          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 127.872 bits (320), Expect = 2.484e-28
Identity = 251/1162 (21.60%), Postives = 469/1162 (40.36%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKN-------DKKFRSSFNKGFTMMER----DELQ--------DFHYRSRFEVSECNNV-----------IVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK--------DTRAAVMVNQDQRKQTDFMAQLFQENFD--INNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDM-MITHGKDSDSWLKMIQDF 3231
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD  +        K  +   NKG  +M       EL          F   +    +   NV           ++D K   +E+L+ +L  +L+ R   L+ +FK         T      N  Q   ++    L  E+ +     I   S+E     T L       + F       VLL LT + Y  L+  +L  + + FS ++ V      + ++   +D D++ ++ QD 
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEE----NTPLDLDDHGGRTF-----LRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDL 1105          

HSP 2 Score: 74.3294 bits (181), Expect = 4.033e-12
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2535 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2628          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 127.872 bits (320), Expect = 2.647e-28
Identity = 205/930 (22.04%), Postives = 387/930 (41.61%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD 2658
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILD 882          

HSP 2 Score: 74.3294 bits (181), Expect = 3.909e-12
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2584 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2677          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 127.872 bits (320), Expect = 2.760e-28
Identity = 205/930 (22.04%), Postives = 387/930 (41.61%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD 2658
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILD 882          

HSP 2 Score: 74.3294 bits (181), Expect = 3.942e-12
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2583 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2676          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Match: ITPR1 (inositol 1,4,5-trisphosphate receptor type 1 [Source:HGNC Symbol;Acc:HGNC:6180])

HSP 1 Score: 127.872 bits (320), Expect = 2.760e-28
Identity = 205/930 (22.04%), Postives = 387/930 (41.61%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD 2658
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILD 882          

HSP 2 Score: 74.3294 bits (181), Expect = 3.942e-12
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2583 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2676          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 80.8777 bits (198), Expect = 1.569e-14
Identity = 68/278 (24.46%), Postives = 116/278 (41.73%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFR-------------DAMNMSSNL----------------------------YCDTLGHC-----YTTLIRFGFIFD------KWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            LV   ++   L +I      L  V  +V ++  S+ W GLL LI++Y F+++ F+ FR              +  +SS +                             C+TL  C     Y  L   G I D       W ++F+ +      F  V+ + +  ++              G+I+D F   R  K+ K   + N CFIC      F+ ++  F  H   EHN+W YLYY++ L+    +++T  + +V +  K +NLD++P  +AL+L
Sbjct: 2526 LVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIF-------------GVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2790          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 80.8777 bits (198), Expect = 1.767e-14
Identity = 68/278 (24.46%), Postives = 116/278 (41.73%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFR-------------DAMNMSSNL----------------------------YCDTLGHC-----YTTLIRFGFIFD------KWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            LV   ++   L +I      L  V  +V ++  S+ W GLL LI++Y F+++ F+ FR              +  +SS +                             C+TL  C     Y  L   G I D       W ++F+ +      F  V+ + +  ++              G+I+D F   R  K+ K   + N CFIC      F+ ++  F  H   EHN+W YLYY++ L+    +++T  + +V +  K +NLD++P  +AL+L
Sbjct: 2557 LVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIF-------------GVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2821          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 80.8777 bits (198), Expect = 1.780e-14
Identity = 68/278 (24.46%), Postives = 116/278 (41.73%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFR-------------DAMNMSSNL----------------------------YCDTLGHC-----YTTLIRFGFIFD------KWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            LV   ++   L +I      L  V  +V ++  S+ W GLL LI++Y F+++ F+ FR              +  +SS +                             C+TL  C     Y  L   G I D       W ++F+ +      F  V+ + +  ++              G+I+D F   R  K+ K   + N CFIC      F+ ++  F  H   EHN+W YLYY++ L+    +++T  + +V +  K +NLD++P  +AL+L
Sbjct: 2536 LVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIF-------------GVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2800          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 80.4925 bits (197), Expect = 1.990e-14
Identity = 68/278 (24.46%), Postives = 116/278 (41.73%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFR-------------DAMNMSSNL----------------------------YCDTLGHC-----YTTLIRFGFIFD------KWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            LV   ++   L +I      L  V  +V ++  S+ W GLL LI++Y F+++ F+ FR              +  +SS +                             C+TL  C     Y  L   G I D       W ++F+ +      F  V+ + +  ++              G+I+D F   R  K+ K   + N CFIC      F+ ++  F  H   EHN+W YLYY++ L+    +++T  + +V +  K +NLD++P  +AL+L
Sbjct: 2582 LVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIF-------------GVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2846          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Match: itr-1 (Inositol 1,4,5-trisphosphate receptor itr-1 [Source:UniProtKB/Swiss-Prot;Acc:Q9Y0A1])

HSP 1 Score: 80.4925 bits (197), Expect = 2.054e-14
Identity = 68/278 (24.46%), Postives = 116/278 (41.73%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFR-------------DAMNMSSNL----------------------------YCDTLGHC-----YTTLIRFGFIFD------KWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            LV   ++   L +I      L  V  +V ++  S+ W GLL LI++Y F+++ F+ FR              +  +SS +                             C+TL  C     Y  L   G I D       W ++F+ +      F  V+ + +  ++              G+I+D F   R  K+ K   + N CFIC      F+ ++  F  H   EHN+W YLYY++ L+    +++T  + +V +  K +NLD++P  +AL+L
Sbjct: 2547 LVHPMIYCILLFDIIFTEETLQNVIASVTRNYQSIVWTGLLALILLYFFSILGFLYFRHDFYLEVDPVENDSSATISSGIPSETCPSEGCPGLQPSEKDDNDDEKKVKSCETLWMCILQTGYQGLRNGGGIGDVLRNPAPWEDMFIWRVAYDMTFFVVLIVIVLNLIF-------------GVIIDTFGDLRAEKNEKEQILKNNCFICGLDRSRFDNRSVTFETHRETEHNIWHYLYYIVMLQIKDETEFTGPESYVAQCVKDRNLDWFPRMQALSL 2811          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0304568)

HSP 1 Score: 79.337 bits (194), Expect = 6.339e-14
Identity = 64/224 (28.57%), Postives = 111/224 (49.55%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--------LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPI 7812
            + FA HL+++A+    L  + Q+V  +   +    +L+ II+Y +T++ F  FR       +   D    C+  L  F F   K +         +  P  D  +     VY  IF +     V II+L II G+I+D F   R+  +S  D+M + CFIC      F+    GF  H+ KEHN+ +Y+++++ L +   ++YT  + +V  MY+ ++ DF+P+
Sbjct: 4882 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDK--KCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYE-----VYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPV 5098          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088638)

HSP 1 Score: 79.337 bits (194), Expect = 6.446e-14
Identity = 64/224 (28.57%), Postives = 111/224 (49.55%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--------LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPI 7812
            + FA HL+++A+    L  + Q+V  +   +    +L+ II+Y +T++ F  FR       +   D    C+  L  F F   K +         +  P  D  +     VY  IF +     V II+L II G+I+D F   R+  +S  D+M + CFIC      F+    GF  H+ KEHN+ +Y+++++ L +   ++YT  + +V  MY+ ++ DF+P+
Sbjct: 4878 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDK--KCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYE-----VYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPV 5094          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088637)

HSP 1 Score: 79.337 bits (194), Expect = 6.447e-14
Identity = 64/224 (28.57%), Postives = 111/224 (49.55%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--------LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPI 7812
            + FA HL+++A+    L  + Q+V  +   +    +L+ II+Y +T++ F  FR       +   D    C+  L  F F   K +         +  P  D  +     VY  IF +     V II+L II G+I+D F   R+  +S  D+M + CFIC      F+    GF  H+ KEHN+ +Y+++++ L +   ++YT  + +V  MY+ ++ DF+P+
Sbjct: 4892 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDK--KCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYE-----VYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPV 5108          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0304572)

HSP 1 Score: 79.337 bits (194), Expect = 6.502e-14
Identity = 64/224 (28.57%), Postives = 111/224 (49.55%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--------LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPI 7812
            + FA HL+++A+    L  + Q+V  +   +    +L+ II+Y +T++ F  FR       +   D    C+  L  F F   K +         +  P  D  +     VY  IF +     V II+L II G+I+D F   R+  +S  D+M + CFIC      F+    GF  H+ KEHN+ +Y+++++ L +   ++YT  + +V  MY+ ++ DF+P+
Sbjct: 4899 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDK--KCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYE-----VYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPV 5115          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Match: RyR (gene:FBgn0011286 transcript:FBtr0088639)

HSP 1 Score: 79.337 bits (194), Expect = 6.610e-14
Identity = 64/224 (28.57%), Postives = 111/224 (49.55%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--------LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPI 7812
            + FA HL+++A+    L  + Q+V  +   +    +L+ II+Y +T++ F  FR       +   D    C+  L  F F   K +         +  P  D  +     VY  IF +     V II+L II G+I+D F   R+  +S  D+M + CFIC      F+    GF  H+ KEHN+ +Y+++++ L +   ++YT  + +V  MY+ ++ DF+P+
Sbjct: 4878 FFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDK--KCHDMLTCFVFHLYKGVRAGGGIGDEIGDPDGDDYE-----VYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRSWDFFPV 5094          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 124.405 bits (311), Expect = 2.019e-27
Identity = 227/1042 (21.79%), Postives = 426/1042 (40.88%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSS--KDVPII-----------SNQDFIAQEWLVNDK---SGLYLLQDGSAIGGIANTLYI--STNAG----KNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD----------------GKNDKKFRSSFNKGFTMME------------------RDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK 2874
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N ++K+  +     + +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+  K+   T   +E  S+T+      YF   I   ++++     N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S  K +P+            +N D + +  LV  +   +G  L +           +++    + G    K+  +L+      H    E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G         + E+ E F    E++ N++      S  + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD                GK     RS    G  M +                  RDE+     +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK
Sbjct:    1 MVDKLSSFLHIGDVCSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHI--CRLCYRVLRYSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGH---TEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTS-------RDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEV-----KAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFK 982          

HSP 2 Score: 75.8702 bits (185), Expect = 1.030e-12
Identity = 68/215 (31.63%), Postives = 114/215 (53.02%), Query Frame = 1
Query: 7357 CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            CD+L  C  T++  G      +   L  P  + +     VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YL++++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2508 CDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRLGLLG 2717          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 123.25 bits (308), Expect = 3.823e-27
Identity = 227/1042 (21.79%), Postives = 425/1042 (40.79%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL--------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSS--KDVPII-----------SNQDFIAQEWLVNDK---SGLYLLQDGSAIGGIANTLYI--STNAG----KNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD----------------GKNDKKFRSSFNKGFTMME------------------RDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK 2874
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                N ++K+  +     + +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+  K+   T   +E  S+T+      YF   I   ++++     N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S  K +P+            +N D + +  LV  +   +G  L +           +++    + G    K+  +L+      H    E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G           E+ E F    E++ N++      S  + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD                GK     RS    G  M +                  RDE+     +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK
Sbjct:    1 MVDKLSSFLHIGDVCSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHI--CRLCYRVLRYSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGH---TEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTS-------SDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEV-----KAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFK 982          

HSP 2 Score: 75.8702 bits (185), Expect = 1.038e-12
Identity = 68/215 (31.63%), Postives = 114/215 (53.02%), Query Frame = 1
Query: 7357 CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            CD+L  C  T++  G      +   L  P  + +     VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YL++++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2508 CDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRLGLLG 2717          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 119.398 bits (298), Expect = 6.541e-26
Identity = 227/1057 (21.48%), Postives = 424/1057 (40.11%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNKLFLSNNIHDPR-----------------------------TVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSS--KDVPII-----------SNQDFIAQEWLVNDK---SGLYLLQDGSAIGGIANTLYI--STNAG----KNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD----------------GKNDKKFRSSFNKGFTMME------------------RDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK 2874
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL      +Y+ +   S +  D                               ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+  K+   T   +E  S+T+      YF   I   ++++     N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S  K +P+            +N D + +  LV  +   +G  L +           +++    + G    K+  +L+      H    E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G         + E+ E F    E++ N++      S  + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD                GK     RS    G  M +                  RDE+     +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK
Sbjct:    1 MVDKLSSFLHIGDVCSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHI--CRLCYRVLRYSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGH---TEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTS-------RDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEV-----KAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFK 997          

HSP 2 Score: 75.8702 bits (185), Expect = 8.284e-13
Identity = 90/344 (26.16%), Postives = 154/344 (44.77%), Query Frame = 1
Query: 7132 ITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRD--------------AMNMSSNLY----------------------------------------CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            I G   ++  Y L  F L+N       L  V ++V ++  S+    +L LI++Y F++V ++ F+D              A   +S+L                                         CD+L  C  T++  G      +   L  P  + +     VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YL++++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2397 ILGLFGHVFFYSLLLFDLVNRE---ETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLAKAQTSDLLAVRRLFTIIINSCILILKCHKIHCLNPTDCVCFIDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRLGLLG 2732          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 119.013 bits (297), Expect = 8.386e-26
Identity = 227/1057 (21.48%), Postives = 424/1057 (40.11%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNKLFLSNNIHDPR-----------------------------TVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSS--KDVPII-----------SNQDFIAQEWLVNDK---SGLYLLQDGSAIGGIANTLYI--STNAG----KNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD----------------GKNDKKFRSSFNKGFTMME------------------RDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK 2874
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL      +Y+ +   S +  D                               ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+  K+   T   +E  S+T+      YF   I   ++++     N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S  K +P+            +N D + +  LV  +   +G  L +           +++    + G    K+  +L+      H    E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G         + E+ E F    E++ N++      S  + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD                GK     RS    G  M +                  RDE+     +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK
Sbjct:    1 MVDKLSSFLHIGDVCSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHI--CRLCYRVLRYSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGH---TEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTS-------RDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEV-----KAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFK 997          

HSP 2 Score: 75.8702 bits (185), Expect = 1.037e-12
Identity = 68/215 (31.63%), Postives = 114/215 (53.02%), Query Frame = 1
Query: 7357 CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            CD+L  C  T++  G      +   L  P  + +     VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YL++++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2485 CDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRLGLLG 2694          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 118.627 bits (296), Expect = 9.609e-26
Identity = 227/1057 (21.48%), Postives = 424/1057 (40.11%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNKLFLSNNIHDPR-----------------------------TVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSS--KDVPII-----------SNQDFIAQEWLVNDK---SGLYLLQDGSAIGGIANTLYI--STNAG----KNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD----------------GKNDKKFRSSFNKGFTMME------------------RDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK 2874
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL      +Y+ +   S +  D                               ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+  K+   T   +E  S+T+      YF   I   ++++     N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S  K +P+            +N D + +  LV  +   +G  L +           +++    + G    K+  +L+      H    E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G         + E+ E F    E++ N++      S  + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD                GK     RS    G  M +                  RDE+     +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK
Sbjct:    1 MVDKLSSFLHIGDVCSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSMDSEHEVIRARARNPQDKVMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPSSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELADQRHAPFRHI--CRLCYRVLRYSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEVAGTVLGEGAEEEEEDEEEVWLFWKDSGGEVKSKSIRELAQDAKDGH---TEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTS-------RDEVKERFSQTMEFVENYLRDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILDCVHISTPFHIKLDREPGKGSNVMRSIHGVGELMTQVVLRGGGFLPASSHNPPDRDEV-----KAQSEPQKQDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFK 997          

HSP 2 Score: 80.1073 bits (196), Expect = 5.145e-14
Identity = 90/330 (27.27%), Postives = 153/330 (46.36%), Query Frame = 1
Query: 7132 ITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRD----AMNMSSN------------------------------------LYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            I G   ++  Y L  F L+N       L  V ++V ++  S+    +L LI++Y F++V ++ F+D     +N  SN                                      CD+L  C  T++  G      +   L  P  + +     VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YL++++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2392 ILGLFGHVFFYSLLLFDLVNRE---ETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYMFFKDDFILEVNRISNGTLVTIIINSCILILKCHKIHCLNPTDCVCFIDDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRLGLLG 2713          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811])

HSP 1 Score: 125.176 bits (313), Expect = 1.522e-27
Identity = 244/1139 (21.42%), Postives = 457/1139 (40.12%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNG------FIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNIHDPRTVLKFHPVN------------------KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNLPVTAQMKWI--------TPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAI------GGIANTLYISTNAGKN--WTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAPYSPSIR------------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHE------LIDPILNVLD------------GKNDKKFRSSFNKGFTMMERDELQDFHYR--------------SRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDI-----QRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTT 3165
            ++ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF VC  +RY   K+Y K K+A          +  L+KL+ AA LE K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + + F I P +K+   G  V +G  V+   + +      +N    Y  ++  PG  E N SL+ N       F+ Y+    D     +L G ++V  +H E E +LT + Y       ++H+ +R      +R S T +T+SN  W +E  +  P       WN + R KH +TG YL    +    +   +  P  ++KF  V                   +  D  + +   VR+ H+ +  W++ T +     +E    +            T    +D+   +AF I  V   E +        + ++ +   +++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++  F        +  +        +P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +G  +      GG  +  Y+S        W   +   + +H   I              E+   ++ +QL L   +   R    I  I+   K ++  +   C+ +E +P + RA FC L++ + ++     +V   P+  A  +  I  P + +I+             K +   +   + +++ N +  + S+ + +  +N L  +V  L  +LI +G++  +  L        +ID + N               GKN ++      +  + M  +  Q  +                 R  V   N ++++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD        A      FD  N   AS     I    +++  ST   ++     +    VL+ LT   Y SL+  SL  + K FS ++ V  T
Sbjct:    2 SEMSSFLHIGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQKQYWKAKQAKQ-DKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQPLHASN----YELTDN-PGCKEVN-SLNSNTSWKINLFMQYRDYMED-----VLKGGDVVRLFHAEQEKFLTCDEY-----KSRLHVFLRTT----LRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLV---MQGPEKMIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLM---------LGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGVM-QSQIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGKMSPEYMSLEYCDEEVWLTWTDKNNDSHEKSIRQLSQEARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEIS---KQLSVDLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVT--PVKFARLWTEI--PMAITIKDYDSNLNDSRDNKKNKFTSTMEFVEDYLNNVV--SESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDNAADGTAPA------FDSTN---ASLNLDRIGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHT 1079          

HSP 2 Score: 88.1965 bits (217), Expect = 2.601e-16
Identity = 46/140 (32.86%), Postives = 80/140 (57.14%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWK 7968
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L  NE   E  +++   + L S +  +    +   +L  +QR ++W+
Sbjct: 2433 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDKLGSTMRLVSHLTMQLSELKEQQRSQQWQ 2572          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811])

HSP 1 Score: 121.324 bits (303), Expect = 2.574e-26
Identity = 247/1161 (21.27%), Postives = 464/1161 (39.97%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNG------FIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNYKN-----------------------KLFLSNNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNLPVTAQMKWI--------TPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWL----------VNDKSGLYLLQDGSAIGGIANTLYISTNAGKNWT------------QLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAPYSPSIR------------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHE------LIDPILNVLD------------GKNDKKFRSSFNKGFTMMERDELQDFHYR--------------SRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDI-----QRIREVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            ++ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF VC  +RY   K+Y K K+A          +  L+KL+ AA LE K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + + F I P +K+   G  V +G  V+   + +      +N    Y  ++  PG  E N SL+ N       F+ Y+    D     +L G ++V  +H E E +LT + Y       ++H+ +R      +R S T +T+SN  W +E  +  P       WN + R KH +TG YL    +                        +L    + +D  ++ +  P   +  D  + +   VR+ H+ +  W++ T +     +E    +            T    +D+   +AF I  V   E +        + ++ +   +++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++  F        +  +        +P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L             +  L +L+ G +  G  +  Y        WT            QLS    +    + E+   ++ +QL L   +   R    I  I+   K ++  +   C+ +E +P + RA FC L++ + ++     +V   P+  A  +  I  P + +I+             K +   +   + +++ N +  + S+ + +  +N L  +V  L  +LI +G++  +  L        +ID + N               GKN ++      +  + M  +  Q  +                 R  V   N ++++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD        A      FD  N   AS     I    +++  ST   ++     +    VL+ LT   Y SL+  SL  + K FS  QE + T     ++   +D D++
Sbjct:    2 SEMSSFLHIGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQKQYWKAKQAKQ-DKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQPLHASN----YELTDN-PGCKEVN-SLNSNTSWKINLFMQYRDYMED-----VLKGGDVVRLFHAEQEKFLTCDEY-----KSRLHVFLRTT----LRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQVDKSHYFRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLM---------LGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGVM-QSQIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGSRRGERDLEYCDEEVWLTWTDKNNDSHEKSIRQLSQ-EARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEIS---KQLSVDLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVT--PVKFARLWTEI--PMAITIKDYDSNLNDSRDNKKNKFTSTMEFVEDYLNNVV--SESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDNAADGTAPA------FDSTN---ASLNLDRIGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNY 1103          

HSP 2 Score: 82.4185 bits (202), Expect = 1.220e-14
Identity = 38/97 (39.18%), Postives = 60/97 (61.86%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRN 7839
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L  N
Sbjct: 2487 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSN 2583          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Match: rasgrp1 (RAS guanyl releasing protein 1 [Source:Xenbase;Acc:XB-GENE-489811])

HSP 1 Score: 120.553 bits (301), Expect = 3.967e-26
Identity = 247/1161 (21.27%), Postives = 464/1161 (39.97%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNG------FIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNYKN-----------------------KLFLSNNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNLPVTAQMKWI--------TPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWL----------VNDKSGLYLLQDGSAIGGIANTLYISTNAGKNWT------------QLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAPYSPSIR------------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHE------LIDPILNVLD------------GKNDKKFRSSFNKGFTMMERDELQDFHYR--------------SRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDI-----QRIREVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            ++ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF VC  +RY   K+Y K K+A          +  L+KL+ AA LE K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + + F I P +K+   G  V +G  V+   + +      +N    Y  ++  PG  E N SL+ N       F+ Y+    D     +L G ++V  +H E E +LT + Y       ++H+ +R      +R S T +T+SN  W +E  +  P       WN + R KH +TG YL    +                        +L    + +D  ++ +  P   +  D  + +   VR+ H+ +  W++ T +     +E    +            T    +D+   +AF I  V   E +        + ++ +   +++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++  F        +  +        +P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L             +  L +L+ G +  G  +  Y        WT            QLS    +    + E+   ++ +QL L   +   R    I  I+   K ++  +   C+ +E +P + RA FC L++ + ++     +V   P+  A  +  I  P + +I+             K +   +   + +++ N +  + S+ + +  +N L  +V  L  +LI +G++  +  L        +ID + N               GKN ++      +  + M  +  Q  +                 R  V   N ++++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD        A      FD  N   AS     I    +++  ST   ++     +    VL+ LT   Y SL+  SL  + K FS  QE + T     ++   +D D++
Sbjct:    2 SEMSSFLHIGDIVSLYAEGTVCGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQKQYWKAKQAKQ-DKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQPLHASN----YELTDN-PGCKEVN-SLNSNTSWKINLFMQYRDYMED-----VLKGGDVVRLFHAEQEKFLTCDEY-----KSRLHVFLRTT----LRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEVREGSLVMQVDKSHYFRKNAGEKIKFRLVAVPHGNDIASLFELDPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLM---------LGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSNNGQNVLDIMITKPNRERQKLMREQNILKQIFGILKAPFKEKGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGVM-QSQIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVNLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTEGEGVLSILEGGGSRRGERDLEYCDEEVWLTWTDKNNDSHEKSIRQLSQ-EARAGNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEIS---KQLSVDLIFLCMADEMLPYEIRASFCHLMLHVHVDRDPQELVT--PVKFARLWTEI--PMAITIKDYDSNLNDSRDNKKNKFTSTMEFVEDYLNNVV--SESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQSILLQAIYSEDGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPIKRKNVDMENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDNAADGTAPA------FDSTN---ASLNLDRIGELAEAMFGSTSMLEVDDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNY 1103          

HSP 2 Score: 82.8037 bits (203), Expect = 1.148e-14
Identity = 38/97 (39.18%), Postives = 60/97 (61.86%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRN 7839
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L  N
Sbjct: 2446 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEHNIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSN 2542          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Match: sfi1 (SFI1 centrin binding protein [Source:Xenbase;Acc:XB-GENE-5749440])

HSP 1 Score: 119.398 bits (298), Expect = 9.104e-26
Identity = 197/914 (21.55%), Postives = 376/914 (41.14%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTN----PNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSN-----------------NIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMR---SQVIWDNASF--ITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLK-GKISNPTSMNDESLTR---YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNLPVTAQM--------KWITPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTL-----------------YISTNA---GKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQ--NSSLIYENTGRNHLIIQVFYLLLNLIKYGYF 2604
            + +  S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K++ K K+A  G+         LKKL+ AA LE K N    ++ +G  +++ ++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P +K+  EG  V +G  V    + +      +N     NP       E      N S   N F+ +     D           +V  +H E E +LT + Y      +K H+ +R      +R S T +T+S   W +E  +  P       WN + R KH +TG YL    K +L +                   + +D  ++ +       R D  + +   VR+ H+ +  W+  T +   T++E    ++    Q   D  +F  I+V + + +  D A +   V              A  +K L+ G I+         L     +F   +    + +   +   P + RQK+MR   ++  +F I++  F +      M        +   P + I  L    + ++     KN +Y+AK+F +    +     +  D IT L H   ++ ++ EK +    I++ + ++  N+   FL +LS  C S    I   Q+ I + ++++  +   L+Q       + N L                 +I +N    GK    L+    +     +E    ++ +QL+L   +   R    I  I+T+   ++  + + C+ +E +P D RA FC L++ + ++           Y   +  +   I+ + Y++    ++ S R   EM   F    E++  ++ +  N    + +  +N L  +V +L  NLI +G++
Sbjct:    1 MPDKMSSFLYIGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPDAGDLANPPKKFRDCLFKVCPMNRYSAQKQFWKAKQAKQGN---NTEAALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDCAGNEGSWFYIQPFWKLRSEGDNVVVGDKVVLMPVNAGQPLHASNIELLDNPGC----KEVNAVNCNTSWKVNLFMKFSDYRDDVLKGGD-----VVRLFHAEQEKFLTCDEY-----EKKQHIFLRTT----LRQSATSATSSKALWEVEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAEVKGELPVHKRKWQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTEEERPVMLKIGTCQTKEDKEAFAIISVPLSEVRDLDFANDANKV-------------LASTVKKLEYGTITQNERRFVTKLLEDLIFFVAGVANNGQEVLDVVVTKPNRERQKLMREQNILAQIFGILKAPFKDKAGEGSMLRLEDLGDQRYAPYKYILRLCYRVLRHSQQDYRKNQEYIAKHFCVMQS-QIGYDILAEDTITALLH---NNRKLLEKHITAKEIETFVNLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICK-FMLSPGNADILIQTKLVSMQMDNPLECSVLQDDMDEEEVWLYWIDSNKEPHGKAIRHLAQEAKEGTKADLEV-LTYYRYQLNLFARMCLDRQYLAINQISTQ---LSVDLILRCMSDESLPFDLRASFCRLMLHIHVDRDPQETVVPVKYARLWTEIPTKISIHDYDS----FTDSSR--DEMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFY 862          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Match: c1qbp (complement component 1, q subcomponent binding protein [Source:Xenbase;Acc:XB-GENE-973232])

HSP 1 Score: 114.005 bits (284), Expect = 3.433e-24
Identity = 191/901 (21.20%), Postives = 368/901 (40.84%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNI------------------------HDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVT--PLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSA---IGGIANTLYI---STNAGKNWTQLSTFFDKTHYLYIESQ--CKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGY 2601
            +++  S FL  GD ++LY+E  + G++   ++  ++++  V    + DL          LF +C  +RY   K++ K   A     +S      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +         + S  +    PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL       L +                            +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  P+    KDE           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF   +    +++   + N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L    + + +  +G +    G     +++    +N       +            E Q    ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   + ++ E F    E++  ++         + +  +N L  +V  L  NLI +G+
Sbjct:    1 MSDKMSSFLHVGDIVSLYAEGSVNGFI---NTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGASSTTDTVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPL-----HASSHQLADNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVSGLLKIDAEPDGGNARMQMVPEKMMCTLISVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNSPI---DKDE-----------EKPVMLRIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLSSIAGKLEKGTITQNERRSVTKLLEELVYFVTGLVNAGQDILEVLVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETNGESPLETGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDQDVLNYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPFDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGTSRDDIKERFAQTMEFVEEYLRDVVGQRFPFADKEKNKLTFEVVNLARNLIYFGF 856          

HSP 2 Score: 76.2554 bits (186), Expect = 1.033e-12
Identity = 34/95 (35.79%), Postives = 57/95 (60.00%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT 7833
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL++++ ++    ++YT  + +V +M K +NLD++P  RA++L 
Sbjct: 2444 IDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLV 2538          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Match: Itpr3 (inositol 1,4,5-triphosphate receptor 3 [Source:MGI Symbol;Acc:MGI:96624])

HSP 1 Score: 127.102 bits (318), Expect = 3.220e-28
Identity = 249/1153 (21.60%), Postives = 468/1153 (40.59%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKN---------------------------KLFLSNNIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-----FGNLPVTAQMKWIT-----PCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANT---LYISTNAGKNWTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMV-----------MDYPITAYSYN-NIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFD------DTSSLHELIDPI------LNVLDGKNDKKFRSSFNKGFTMMERDELQDFHY------------------RSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIR---EVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            N+ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K+Y K K+           +  L+KL+ AA +E K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N   S      E      N S   N F+ ++    +     +L G ++V  +H E E +LT + Y RG++   +   +R+       S T +T+SN  W +E  +  P       WN + R KH +TG YL      +YK                            +L    + +D  ++ +  P    + D F+ +   VR+ H+ +  W++ T      ++E    +            T    +D+   +AF I  V   E +        + ++ S   K++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++       G  P+  +++ ++     P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +   +  +A +   L I  +  + W   +   ++ H   +              E+   ++ +QL L   +   R    I+ I+   K +   +   C+ +E +P D RA FC L++ + ++     +V           +   IT   Y+ N+ A        K +   +   + +++ N +  + ++ + N  +N L  +V  L  NLI +G++        T +L  +ID I      L   +    K  R S      MM    L                       RS+FE +E + V+++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD     D  A  F  +    N+ +  ++  ++    K+  SS    D +  R    VLL LT + Y SL+  +L  + K FS  QE + T     ++   +D +++
Sbjct:    2 NEMSSFLHIGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQ-DKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEE-----VLKGGDVVRLFHAEQEKFLTCDEY-RGKLQVFLRTTLRQ-------SATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRL---------MLGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLV-RLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQS-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEIS---KQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDK---KNKFASTMEFVEDYLNNVV--SEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQAPAAMLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNE-HTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQD--SGADGTAPAFDSSTATMNLDRIGEQAEAMFGVGKT--SSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENY 1107          

HSP 2 Score: 82.8037 bits (203), Expect = 8.807e-15
Identity = 63/174 (36.21%), Postives = 93/174 (53.45%), Query Frame = 1
Query: 7315 VLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +L  D    S+   CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L
Sbjct: 2440 ILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSL 2609          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Match: Itpr2 (inositol 1,4,5-triphosphate receptor 2 [Source:MGI Symbol;Acc:MGI:99418])

HSP 1 Score: 117.472 bits (293), Expect = 2.278e-25
Identity = 199/927 (21.47%), Postives = 378/927 (40.78%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTN----PNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNKLFLSNNIHD-----PRT----------VLKFHPVNKD--------------RDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMR---SQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLK-GKISNPTSMNDESLTRYFTEAIGEISKNL-----CIQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNLPVTAQM--------KWITPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTL-----------------YISTNA---GKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQ--NSSLIYENTGRNHLIIQVFYLLLNLIKYGYF 2604
            +++  S FL  GD ++LY+E  + G++   S+  ++++  V   ++ DL          LF+VC  +RY   K+Y K K+A  G   +      LKKL+ AA LE K N    ++ +G  +++ ++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P +K+  EG  + +G  V    + +      +N     NP       E      N S     F+ + S   D     +L G ++V  +H E E +LT + Y      +K H+ +R      +R S T +T+S   W IE  +  P       WN + R KH +TG YL      +Y++      N+ D     P+            L   P   D               D  + +   VR+ H+ +  W+  T +   T++E    ++    Q   D  +F  V +   +  D      D A    ++       A  +K L+ G I+         L       + +++ N       +   P + RQK+MR   ++  +F I++  F        M        +   P + +  L    + ++     KN +Y+AK F +    +     +  D IT L H   ++ ++ EK +    I++ + ++  N+   FL +LS  C S    I   Q+ I + ++++  +   L+Q       + N +                 +I +N    GK    L+    +     +E    ++ +QL+L   +   R    I  I+T+   ++  + + C+ +E +P D RA FC L++ + ++           Y   +  +   IT + Y++I      +   + +M   F    E++  ++ +  N    + +  +N L  +V +L  NLI +G++
Sbjct:    1 MSDKMSSFLYIGDIVSLYAEGSVNGFI---STLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQG---NHTEAALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNVELLDNPGC----KEVNAVNCNTSWKITLFMKFSSYRED-----VLKGGDVVRLFHAEQEKFLTCDDY-----EKKQHIFLRTT----LRQSATSATSSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKNVKDGEIPTPKKKRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTSTTIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRD-----LDFANDANKV------LATTVKKLENGSITQNERRFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQS-QIGYDILAEDTITALLH---NNRKLLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICK-FMLSPGNADILIQTKLVSMQVENPMESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEV-LTYYRYQLNLFARMCLDRQYLAINQISTQ---LSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSI------TDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFY 877          

HSP 2 Score: 82.4185 bits (202), Expect = 1.135e-14
Identity = 89/338 (26.33%), Postives = 147/338 (43.49%), Query Frame = 1
Query: 7153 LVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNM---------------------------------------SSNLY-----------CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALG-EGENTLKV 8007
             V  + ++F L ++      L  V ++V ++  S+    +L LI++Y F+++ F+  +D   M                                       SSN             CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW YLY+++ ++    ++YT  + +V +M   KNLD++P  RA++L  NE  +E  +++   E L S +  +        +L  +  +++  K+ LG  G NT  V
Sbjct: 2361 FVHEFFYSFLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKNRTPVTGNHGVPTMTLSSMMETCQKENCSPTIPSSNTAGEEGEDGIERTCDTLLMCIVTVLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDPTEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQLSGQLAELKEQMTEQRKNKQRLGFLGSNTPHV 2694          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Match: Ryr1 (ryanodine receptor 1, skeletal muscle [Source:MGI Symbol;Acc:MGI:99659])

HSP 1 Score: 91.2781 bits (225), Expect = 2.379e-17
Identity = 66/225 (29.33%), Postives = 115/225 (51.11%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMS-----SNLYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   N S      ++ CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +Y+++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4831 FFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYE-----LYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 5047          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Match: Ryr1 (ryanodine receptor 1, skeletal muscle [Source:MGI Symbol;Acc:MGI:99659])

HSP 1 Score: 91.2781 bits (225), Expect = 2.543e-17
Identity = 66/225 (29.33%), Postives = 115/225 (51.11%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMS-----SNLYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   N S      ++ CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +Y+++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4805 FFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYE-----LYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 5021          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Match: Ryr1 (ryanodine receptor 1, skeletal muscle [Source:MGI Symbol;Acc:MGI:99659])

HSP 1 Score: 90.8929 bits (224), Expect = 2.742e-17
Identity = 66/225 (29.33%), Postives = 115/225 (51.11%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMS-----SNLYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   N S      ++ CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +Y+++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4803 FFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYE-----LYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 5019          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Match: sp|P70227|ITPR3_MOUSE (Inositol 1,4,5-trisphosphate receptor type 3 OS=Mus musculus OX=10090 GN=Itpr3 PE=1 SV=3)

HSP 1 Score: 127.102 bits (318), Expect = 2.252e-27
Identity = 249/1153 (21.60%), Postives = 468/1153 (40.59%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKN---------------------------KLFLSNNIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-----FGNLPVTAQMKWIT-----PCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANT---LYISTNAGKNWTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMV-----------MDYPITAYSYN-NIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFD------DTSSLHELIDPI------LNVLDGKNDKKFRSSFNKGFTMMERDELQDFHY------------------RSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIR---EVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            N+ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K+Y K K+           +  L+KL+ AA +E K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N   S      E      N S   N F+ ++    +     +L G ++V  +H E E +LT + Y RG++   +   +R+       S T +T+SN  W +E  +  P       WN + R KH +TG YL      +YK                            +L    + +D  ++ +  P    + D F+ +   VR+ H+ +  W++ T      ++E    +            T    +D+   +AF I  V   E +        + ++ S   K++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++       G  P+  +++ ++     P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +   +  +A +   L I  +  + W   +   ++ H   +              E+   ++ +QL L   +   R    I+ I+   K +   +   C+ +E +P D RA FC L++ + ++     +V           +   IT   Y+ N+ A        K +   +   + +++ N +  + ++ + N  +N L  +V  L  NLI +G++        T +L  +ID I      L   +    K  R S      MM    L                       RS+FE +E + V+++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD     D  A  F  +    N+ +  ++  ++    K+  SS    D +  R    VLL LT + Y SL+  +L  + K FS  QE + T     ++   +D +++
Sbjct:    2 NEMSSFLHIGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQ-DKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEE-----VLKGGDVVRLFHAEQEKFLTCDEY-RGKLQVFLRTTLRQ-------SATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGLGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRL---------MLGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLV-RLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQS-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEIS---KQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDK---KNKFASTMEFVEDYLNNVV--SEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQAPAAMLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPAGVGVPEQLDRSKFEDNE-HTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQD--SGADGTAPAFDSSTATMNLDRIGEQAEAMFGVGKT--SSMLEVDDEGGRMFLRVLLHLTMHDYPSLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENY 1107          

HSP 2 Score: 82.8037 bits (203), Expect = 6.161e-14
Identity = 63/174 (36.21%), Postives = 93/174 (53.45%), Query Frame = 1
Query: 7315 VLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +L  D    S+   CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L
Sbjct: 2440 ILEEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSL 2609          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Match: sp|Q63269|ITPR3_RAT (Inositol 1,4,5-trisphosphate receptor type 3 OS=Rattus norvegicus OX=10116 GN=Itpr3 PE=1 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 3.570e-26
Identity = 247/1153 (21.42%), Postives = 466/1153 (40.42%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKN---------------------------KLFLSNNIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-----FGNLPVTAQMKWIT-----PCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANT---LYISTNAGKNWTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMV-----------MDYPITAYSYN-NIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFD------DTSSLHELID------PILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHY------------------RSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIR---EVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            N+ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K+Y K K+           +  L+KL+ AA +E K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N   S      E      N S   N F+ ++    +     +L G ++V  +H E E +LT + Y RG++   +   +R+       S T +T+SN  W +E  +  P       WN + R KH +TG YL      +YK                            +L    + +D  ++ +  P    + D F+ +   VR+ H+ +  W++ T      ++E    +            T    +D+   +AF I  V   E +        + ++ S   K++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++       G  P+  +++ ++     P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +   +  +A +   L I  +  + W   +   ++ H   +              E+   ++ +QL L   +   R    I+ I+   K +   +   C+ +E +P D RA FC L++ + ++     +V           +   IT   Y+ N+ A        K +   +   + +++ N +    ++ + N  +N L  +V  L  NLI +G++        T +L  +ID       +L   +    K  R S      MM    L                       RS+FE +E + V+++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD     D  A  F  +    N+ +  ++  ++    K+  SS    D +  R    VLL LT + Y  L+  +L  + K FS  QE + T     ++   +D +++
Sbjct:    2 NEMSSFLHIGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQ-DKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEE-----VLKGGDVVRLFHAEQEKFLTCDEY-RGKLQVFLRTTLRQ-------SATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAGPGAQSRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNAPIDVEEERPIRL---------MLGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMRDENILKQIFGILKAPFRDKGGEGPLV-RLEELSDQKNAPYQYMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQS-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEIS---KQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDK---KNKFASTMEFVEDYLNNVV--GEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQAPAAVLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPTGVGVPEQLDRSKFEDNE-HTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQD--SGADGTAPAFDSSTANMNLDRIGEQAEAMFGVGKT--SSMLEVDDEGGRMFLRVLLHLTMHDYPPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENY 1107          

HSP 2 Score: 81.6481 bits (200), Expect = 1.099e-13
Identity = 69/216 (31.94%), Postives = 111/216 (51.39%), Query Frame = 1
Query: 7342 SSNLYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALG 7983
            S+   CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L   E   E  +++   E L S +  +        +L  +  +++ +++ LG
Sbjct: 2449 STERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTAQLNELKEQMTEQRKRRQRLG 2660          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Match: sp|Q8WN95|ITPR3_BOVIN (Inositol 1,4,5-trisphosphate receptor type 3 OS=Bos taurus OX=9913 GN=ITPR3 PE=2 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 6.754e-26
Identity = 237/1130 (20.97%), Postives = 455/1130 (40.27%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKN---------------------------KLFLSNNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIEL-----FGNLPVTAQMKWIT-----PCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANT---LYISTNAGKNWTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMV-----------MDYPITAYSYN-NIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHE------LIDPILNVLD--GKNDKKFRSSFNKGFTMMERDELQDFHYR---------------SRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIR---EVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTT 3165
            ++ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K+Y K K+           +  L+KL+ AA +E K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N   S      E      N S   N F+ ++    +           +V  +H E E +LT + Y RG++   +   +R+       S T +T+SN  W +E  +  P       WN + R KH +TG YL      +YK                            +L    + +D  ++ +  P   +  D F+ +   VR+ H+ +  W++ T +    ++E    +            T    +D+   +AF I  V   E +        + ++ S   K+     S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I++       G  P+  +++ ++     P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +   +  +A +   L I  +  + W   +   ++ H   +              E+   ++ +QL L   +   R    I+ I+ +   +   +   C+ +E +P D RA FC L++ + ++     +V           +   IT   Y+ N+ A        K +   +   + +++ N +  + ++ + N  +N L  +V  L  NLI +G++  +  L        +ID +    D  GKN ++         + M  +  Q                    S+FE +E + V+++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD     D  A  F       N+ +  ++  ++    K+  SS    D +  R    VL+ LT + Y  L+  +L  + K FS ++ V  T
Sbjct:    2 SEMSSFLHIGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQ-DKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVLKGGD-----VVRLFHAEQEKFLTCDEY-RGKLQVFLRTTLRQ-------SATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGTGAQGRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDVEEERPIRLM---------LGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLASAVEKLHEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQIFGILKAPFRDKGGEGPLV-RLEELSDQKNAPYQHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQS-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQ---LGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDK---KNKFASTMEFVEDYLNNVV--SEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQAYEDPGGKNVRRSTQGVGHMMSTMVLNRKQSVFGGPSLPAGAGAPEPLDGSKFEENE-DIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQD--SGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKT--SSMLEVDDEGGRMLLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEVMHT 1084          

HSP 2 Score: 83.5741 bits (205), Expect = 3.509e-14
Identity = 64/174 (36.78%), Postives = 93/174 (53.45%), Query Frame = 1
Query: 7315 VLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            VL  D    S+   CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L
Sbjct: 2434 VLAEDEEPDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKFEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSL 2603          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Match: sp|Q14643|ITPR1_HUMAN (Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3)

HSP 1 Score: 122.094 bits (305), Expect = 7.226e-26
Identity = 205/945 (21.69%), Postives = 387/945 (40.95%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL-----------------------------NYKNKLFLS----NNIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIG-----GIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCK------------------FFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAP-----YSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD 2658
            +++  S FL  GD  +LY+E    G++   S+  ++++  V   ++ DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT +     E  +K H+ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL                               N + K+  S       +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T  I   K+E           +    + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  S+T+      YF        +++   + + P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I +  L N  +   L++    +      G+++T   +  AG++  ++  F+  ++        +                  ++ +QL+L   +   R    I  I+ +   +   + + C+ +E +P D RA FC L++ + ++      V   P+  A  ++ I +      Y  S   K E+ E F    E++  ++         + +  +N L  +V  L  NLI +G++ + S L  L   +L +LD
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGD-VVRLFHAEQEKFLTCD-----EHRKKQHVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTN-IPIDKEE-----------EKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVL-NPTNADILIETKLVLSRFEFEGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLFARMCLDRQYLAINEISGQ---LDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQVT--PVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLAILD 897          

HSP 2 Score: 74.3294 bits (181), Expect = 1.863e-11
Identity = 34/94 (36.17%), Postives = 56/94 (59.57%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHNMW YL +++ ++    ++YT  + +V +M K +NLD++P  RA++L
Sbjct: 2598 IDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSL 2691          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Match: sp|Q14573|ITPR3_HUMAN (Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2)

HSP 1 Score: 119.783 bits (299), Expect = 3.361e-25
Identity = 243/1153 (21.08%), Postives = 465/1153 (40.33%), Query Frame = 1
Query:  118 NDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNK---------------------------LFLSNNIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNP-TSMNDESLT-------RYFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQII-----ELFGNLPVTAQMKWIT-----PCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANT---LYISTNAGKNWTQLSTFFDKTHYLYI--------------ESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMV-----------MDYPITAYSYN-NIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGY--FDDTSSLHELIDPILNVLDG----------KNDKKFRSSFNKGFTMMERDELQDFHY------------------RSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIR---EVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSW 3210
            ++ S FL  GD ++LY+E  + G++   S+  ++++  V    + DL          LF+VC  +RY   K+Y K K+           +  L+KL+ AA +E K N    K+  G  +++G +IQL H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N   S      E      N S   N F+ ++    +     +L G ++V  +H E E +LT + Y +G++   +   +R+       S T +T+SN  W +E  +  P       WN + R KH +TG YL      +YK                             L    + +D  ++ +  P    + D F+ +   VR+ H+ +  W++ T +    ++E    +            T    +D+   +AF I  V   E +        + ++ S   K++    S ND            +F   +    +N+   +   P + RQK+MR   ++  +F I+     E  G  P+  +++ ++     P Q +F L    + ++     KN +++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S  + I   Q+ I +  L    S + +  +   +  +A +   L I  +  + W   +   ++ H   +              E+   ++ +QL L   +   R    I+ I+ +   +   +   C+ +E +P D RA FC L++ + ++     +V           +   IT   Y+ N+ A        K +   +   + +++ N +  + ++ + N  +N L  +V  L  NLI +G+  F +   L   +  I++ + G             K  R S      MM    L                       RS+FE +E + V+++ K   LE+L+ +L  +L+ R   L+ +FK     V   QD     D  A  F       N+ +  ++  ++    K+  SS    D +  R    VL+ LT + Y  L+  +L  + K FS  QE + T     ++   +D +++
Sbjct:    2 SEMSSFLHIGDIVSLYAEGSVNGFI---STLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQ-DKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEE-----VLKGGDVVRLFHAEQEKFLTCDEY-KGKLQVFLRTTLRQ-------SATSATSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAGMGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHLCTNTWIQSTNVPIDIEEERPIRLM---------LGTCPTKEDK---EAFAIVSVPVSEIRDLDFANDASSMLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKLMREQNILKQVFGILKAPFREKGGEGPLV-RLEELSDQKNAPYQHMFRLCYRVLRHSQEDYRKNQEHIAKQFGMMQS-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVSLVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSHEYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMCLDRQYLAIDEISQQ---LGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVKFARLWTEIPTAITIKDYDSNLNASRDDK---KNKFANTMEFVEDYLNNVV--SEAVPFANEEKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENE-DIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQD--SGADGTAPAFDSTTANMNLDRIGEQAEAMFGVGKT--SSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEAMHTFKQVQLLISAQDVENY 1107          

HSP 2 Score: 83.9593 bits (206), Expect = 2.639e-14
Identity = 65/177 (36.72%), Postives = 94/177 (53.11%), Query Frame = 1
Query: 7315 VLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRN 7839
            VL  D    S+   CDTL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW+YLY+++ +R    +DYT  + +V +M K+KNLD++P  RA++L  N
Sbjct: 2441 VLEEDRELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILRKPSKDESLFPARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSN 2613          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Match: A0A1S3H6U3 (inositol 1,4,5-trisphosphate receptor type 1 isoform X7 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 866.685 bits (2238), Expect = 0.000e+0
Identity = 647/2408 (26.87%), Postives = 1160/2408 (48.17%), Query Frame = 1
Query:  127 SQFLSFGDYIALYSEQDLGYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRS-ETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNIHDPRTVLKFHPV------NKDRDEFIRKGIN----VRVEHVISGRWLKVTPLITYTKDE---FSNEMRSQVI-WDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIE-LFGNLPVTAQMKWITPCQEIFSLINLYI-GNNSKNTDYVAKYFQIF---------------------TDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDK--------------SGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPITAYSYNNIGAP---YSPSIR-------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFD-INNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQLDILITGDWNHSALSNYRSILASIRAYCTL---PSCNIPNVVFQKILYSCNIVDILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCLKVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLF-SEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVES-----------IKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMT----------ETLRAXXXXXXXXXXXXLMI--KNVKLII----QILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTF----------KEFLQT----HKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKE--------ETQFRVRRQTLTNMNLTVYYECKDYFAEID---------------KIKKSVLDNVTPLKFQS----------IIEN----------------------GFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKM------SAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKA--NPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLT-------NPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLC 6816
             +FL  GDYI+L+ E+  GY+ +  +S   N  ++Y  Q    P  +P    + F VC+ +RYK++K+YRKL  A    P + +    + + K +A  E++DN+   KR  G+++R+G+IIQL+HVF+  ++HI++ + S   K+     L  Y+ K AQF+I+P+YKV  EG  V I   + +ES  S+ +YFH+    S P + E +   SE N+ + + GF V +        +  + G + +  +H+E EAYL AEG F   + E++H+RIR+ID L+ R+L+P  ++ TYW +E  +   +   + W   +RL+H +T  +L L+   ++ L+   +DPR+V +FHPV      + D D   +  I+     R+EHV++G WL       Y +       N+   Q + WD      ++  +++RY D F I +V   +    +   G  P +  L         +N    T   T A+ E+ + + I     K+ QK+MR  +++D L Q+++    + P +  +  ++  +E + ++  Y+ GN+ KN  Y AKY + F                      DP      I  +V  ML  +I  + ++ +++    I   + ++   +NY FL  L+  C      I+ NQ +I + WL +DK              + +YL++ G  I    N +YIST+AG  W  L  F +     Y E +  +   QLDLL  +  GRN   I +IT     +TW     C+++E +P   RAK+C LII LF++ G    V+D     + Y +I  P   YS   +         QE+   FP +R+WI  F+  N  +     G+N LI QV  LL  L+++G +     +  L+ P++ +LDG+ND+ F  +     +   +  ++ +    RFE S     +VDAK  GL VLE+L  FQ N R E  V  FK   A    N  ++K    ++ L  +++D  N  KK  ++ +     L+++  S+ YFD++ I  + LDL++YKY+ +L +SL  + K++SS+  +F  A   ++   ++S      I    P +  L    +N         +      +  L   P+   P  + QKIL +  ++D++F +  +E   +                   E    + L++G+ ++ L+ +A+    VQ  +  RL+ +M+++       ++L + +FA  ++  + + P  I  +      +++ AP+ L+L+  + +V+  +  ++ N   + K +M+ +       + S E++L + +    +  + + + L+ L+    E    ++ES  QT++ ++  +++  +   D  ++   L+++  +Y+K+         I +    L   R  W  +++           I E  VK ++ ++   P+       A+ + ++     +  + +  D V+PF+           + L       V      L++    V  ++     +  ++    S+L    I       + L+NY    SL+P  V+L  N         + +          +E + T    ++ E +LN++F+ F  N   +  G N+  +Q+K+          S +EYT +   E LPLGEEFQ+ V+ F+  +E    KR+  +  +++ L +    +  K G        + D L+I   +ILRAV+ NE ++L EDW E   +  +  QL+ I  +Q+    ++  E VL H  R  + +  E  AFL ++ FNA+  VQ  + + F    TETFFFAI+  L I    +K+ RR L  + + R+KE        +T   V R+ +     ++    +D  + +                K+    L+  TPL F S          ++E                       G+ +L++++L ++C+GQ   +QDY+R Q DN KS N+V  T   VN +Y+NI ++TI ++ Q+   LN+   GNQ NR+ L++ K++DYINFILR  ++ G   +  L+LR+++ANL+++L+EE+     ++A+E+  TVDK+A++  ++  Y               +  + P  K  I  ++   + NL  +    L+++      + +K++ Y++G+ Y  ++ RF DIDP ++   A   +T    AAY   KK   SIE++KD  +Q+VHFR+KN+ V+RE++ EK+KWDVDR+S ++K+RD   W+  ++ D+   +K   NP+ +F  + W LWNYL ILLS+ +N++ML ++K+   +       N+T       NP PD +   +  + +  +   H +FSL +LI+Y L + P   ++  + +   RLC
Sbjct:    2 GEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHS----SVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSDENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSPPNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDEPYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMK-THQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYL--LSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKASTSVMIKQYHLVVVDPTLKGD-IGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANADSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRDWIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKT--AETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHP--MNQKILINHGVLDLIFAILSQEVDVQIT-----------------EQAAPMELVFGKALNLLRFLAQGNEDVQAKMNDRLDSLMNIKLVPSHLAIAL-REVFAGNQNNCLKIQPKQILKIVHLAGENQDRAPEFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTM-----IESGAGDLPHDRHVWIYIQALAREAESLKTYISENEVKTVEVMRAPPPKG------AVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYP---SLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHK---------SKREYTEIGGDEDLPLGEEFQAHVRCFVKHNEKNIAKRYQNVSKLVQQLAVSANAVNPKDG------TYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQRTMLDVFKSMRTETFFFAIRIRLEIAANGLKE-RRALATQHEARVKESMTQAKSLQTNLTVGRKAMKARANSLRALQRDRQSGLTSISPASSKCNSLQRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEEDDVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKYEGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCY---------------SIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDP-VLNEKAGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVLMLWAWKAPYDM--SQAPENMTHLDHAIYNPNPDTSSVEIYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLC 2331          

HSP 2 Score: 160.229 bits (404), Expect = 5.224e-35
Identity = 99/281 (35.23%), Postives = 161/281 (57.30%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT--RNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTL 8001
            Y FAFHL+NI      L GV +AV Q+  S+ WVG+L +II Y + L+ F   R         YC TL  C  T+IR+G I   +  L +P+  S+ NF++   +++F +   I++  I LN+I GI+VD F+  R+LK +   DM + CFICSR S++FE    GF  H  +EHNMW+Y+++ I L   K +DYTAL  HV +  + +  +F+P++ AL+LT   +    + + + E    L+    E ++ ++  E+  R+++ ++  ++AL    +TL
Sbjct: 2384 YFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPE--SENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMREEEHRRQKQWQEMYRKALSGSHDTL 2662          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Match: A0A1S3H6U8 (inositol 1,4,5-trisphosphate receptor type 3 isoform X12 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 860.522 bits (2222), Expect = 0.000e+0
Identity = 647/2406 (26.89%), Postives = 1163/2406 (48.34%), Query Frame = 1
Query:  127 SQFLSFGDYIALYSEQDLGYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRS-ETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNIHDPRTVLKFHPV------NKDRDEFIRKGIN----VRVEHVISGRWLKVTPLITYTKDE---FSNEMRSQVI-WDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIE-LFGNLPVTAQMKWITPCQEIFSLINLYI-GNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDK--------------SGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPITAYSYNNIGAP---YSPSIR-------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFD-INNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQLDILITGDWNHSALSNYRSILASIRAYCTL---PSCNIPNVVFQKILYSCNIVDILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCLKVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFS-EIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVES-----------IKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMT----------ETLRAXXXXXXXXXXXXLMI--KNVKLII----QILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTF----------KEFLQTH----KEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFA-----------IKEFLAI-------FEEDM---KKLRRNLNAKVK--------ERIKEETQF-------------RVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQS----------IIEN----------------------GFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKM------SAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKA--NPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLT-------NPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLC 6816
             +FL  GDYI+L+ E+  GY+ +  +S   N  ++Y  Q    P  +P    + F VC+ +RYK++K+YRKL  A    P + +    + + K +A  E++DN+   KR  G+++R+G+IIQL+HVF+  ++HI++ + S   K+     L  Y+ K AQF+I+P+YKV  EG  V I   + +ES  S+ +YFH+    S P + E +   SE N+ + + GF V +        +  + G + +  +H+E EAYL AEG F   + E++H+RIR+ID L+ R+L+P  ++ TYW +E  +   +   + W   +RL+H +T  +L L+   ++ L+   +DPR+V +FHPV      + D D   +  I+     R+EHV++G WL       Y +       N+   Q + WD      ++  +++RY D F I +V   +    +   G  P +  L         +N    T   T A+ E+ + + I     K+ QK+MR  +++D L Q+++    + P +  +  ++  +E + ++  Y+ GN+ KN  Y AKY + F         I  +V  ML  +I  + ++ +++    I   + ++   +NY FL  L+  C      I+ NQ +I + WL +DK              + +YL++ G  I    N +YIST+AG  W  L  F +     Y E +  +   QLDLL  +  GRN   I +IT     +TW     C+++E +P   RAK+C LII LF++ G    V+D     + Y +I  P   YS   +         QE+   FP +R+WI  F+  N  +     G+N LI QV  LL  L+++G +     +  L+ P++ +LDG+ND+ F  +     +   +  ++ +    RFE S     +VDAK  GL VLE+L  FQ N R E  V  FK   A    N  ++K    ++ L  +++D  N  KK  ++ +     L+++  S+ YFD++ I  + LDL++YKY+ +L +SL  + K++SS+  +F  A   ++   ++S      I    P +  L    +N         +      +  L   P+   P  + QKIL +  ++D++F +  +E   +                   E    + L++G+ ++ L+ +A+    VQ  +  RL+ +M+++       ++L + +FA  ++  + + P  I  +      +++ AP+ L+L+  + +V+  +  ++ N   + K +M+ +       + S E++L + +    +  + + + L+ L+    E    ++ES  QT++ ++  +++ +    D  ++   L+++  +Y+K+         I +    L   R  W  +++           I E  VK ++ ++   P+       A+ + ++     +  + +  D V+PF+           + L       V      L++    V  ++     +  ++    S+L    I       + L+NY    SL+P  V+L  N         + +          +E + T+    + E +LN++F+ F  N   +  G N+  +Q+K+          S +EYT +   E LPLGEEFQ+ V+ F+  +E    KR+  +  +++ L +    +  K G        + D L+I   +ILRAV+ NE ++L EDW E   +  +  QL+ I  +Q+    ++  E VL H  R  + +  E  AFL ++ FNA+  VQ+ +  +F+ +  E+FFFA           IKE  A+        +E M   K L+ NL    K        ER + +++              R R+  LT+++     +C     +  K+    L+  TPL F S          ++E                       G+ +L++++L ++C+GQ   +QDY+R Q DN KS N+V  T   VN +Y+NI ++TI ++ Q+   LN+   GNQ NR+ L++ K++DYINFILR  ++ G   +  L+LR+++ANL+++L+EE+     ++A+E+  TVDK+A++  ++  Y               +  + P  K  I  ++   + NL  +    L+++      + +K++ Y++G+ Y  ++ RF DIDP ++   A   +T    AAY   KK   SIE++KD  +Q+VHFR+KN+ V+RE++ EK+KWDVDR+S ++K+RD   W+  ++ D+   +K   NP+ +F  + W LWNYL ILLS+ +N++ML ++K+   +       N+T       NP PD +   +  + +  +   H +FSL +LI+Y L + P   ++  + +   RLC
Sbjct:    2 GEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHS----SVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSDENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSPPNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDEPYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMK-THQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYL--LSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKGDIGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANADSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRDWIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKT--AETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHP--MNQKILINHGVLDLIFAILSQEVDVQIT-----------------EQAAPMELVFGKALNLLRFLAQGNEDVQAKMNDRLDSLMNIKLVPSHLAIAL-REVFAGNQNNCLKIQPKQILKIVHLAGENQDRAPEFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTM-----IESGAGDLPHDRHVWIYIQALAREAESLKTYISENEVKTVEVMRAPPPKG------AVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYP---SLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHK---------SKREYTEIGGDEDLPLGEEFQAHVRCFVKHNEKNIAKRYQNVSKLVQQLAVSANAVNPKDG------TYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQKAMLEYFMSTKKESFFFAIRCRLQLSAIAIKERRALATQHEARVKESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSIS-PASSKCNSL--QRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEEDDVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKYEGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCY---------------SIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDP-VLNEKAGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVLMLWAWKAPYDM--SQAPENMTHLDHAIYNPNPDTSSVEIYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLC 2328          

HSP 2 Score: 160.229 bits (404), Expect = 5.585e-35
Identity = 99/281 (35.23%), Postives = 161/281 (57.30%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT--RNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTL 8001
            Y FAFHL+NI      L GV +AV Q+  S+ WVG+L +II Y + L+ F   R         YC TL  C  T+IR+G I   +  L +P+  S+ NF++   +++F +   I++  I LN+I GI+VD F+  R+LK +   DM + CFICSR S++FE    GF  H  +EHNMW+Y+++ I L   K +DYTAL  HV +  + +  +F+P++ AL+LT   +    + + + E    L+    E ++ ++  E+  R+++ ++  ++AL    +TL
Sbjct: 2381 YFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPE--SENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMREEEHRRQKQWQEMYRKALSGSHDTL 2659          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Match: A0A1S3H6V5 (inositol 1,4,5-trisphosphate receptor type 3 isoform X2 OS=Lingula unguis OX=7574 GN=LOC106152615 PE=4 SV=1)

HSP 1 Score: 853.203 bits (2203), Expect = 0.000e+0
Identity = 649/2428 (26.73%), Postives = 1165/2428 (47.98%), Query Frame = 1
Query:  124 FSQFLSFGDYIALYSEQDLGYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRS-ETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNIHDPRTVLKFHPV------NKDRDEFIRKGIN----VRVEHVISGRWLKVTPLITYTKDE---FSNEMRSQVI-WDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIE-LFGNLPVTAQMKWITPCQEIFSLINLYI-GNNSKNTDYVAKYFQIF---------------------TDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDK--------------SGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPITAYSYNNIGAP---YSPSIR-------HKQEMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFD-INNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQLDILITGDWNHSALSNYRSILASIRAYCTL---PSCNIPNVVFQKILYSCNIVDILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCLKVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFS-EIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVES-----------IKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMT----------ETLRAXXXXXXXXXXXXLMI--KNVKLII----QILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTF----------KEFLQTH----KEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFA-----------IKEFLAI-------FEEDM---KKLRRNLNAKVK--------ERIKEETQF-------------RVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQS----------IIEN----------------------GFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKM------SAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKA--NPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLT-------NPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLC 6816
              +FL  GDYI+L+ E+  GY+ +  +S   N  ++Y  Q    P  +P    + F VC+ +RYK++K+YRKL  A    P + +    + + K +A  E++DN+   KR  G+++R+G+IIQL+HVF+  ++HI++ + S   K+     L  Y+ K AQF+I+P+YKV  EG  V I   + +ES  S+ +YFH+    S P + E +   SE N+ + + GF V +        +  + G + +  +H+E EAYL AEG F   + E++H+RIR+ID L+ R+L+P  ++ TYW +E  +   +   + W   +RL+H +T  +L L+   ++ L+   +DPR+V +FHPV      + D D   +  I+     R+EHV++G WL       Y +       N+   Q + WD      ++  +++RY D F I +V   +    +   G  P +  L         +N    T   T A+ E+ + + I     K+ QK+MR  +++D L Q+++    + P +  +  ++  +E + ++  Y+ GN+ KN  Y AKY + F                      DP      I  +V  ML  +I  + ++ +++    I   + ++   +NY FL  L+  C      I+ NQ +I + WL +DK              + +YL++ G  I    N +YIST+AG  W  L  F +     Y E +  +   QLDLL  +  GRN   I +IT     +TW     C+++E +P   RAK+C LII LF++ G    V+D     + Y +I  P   YS   +         QE+   FP +R+WI  F+  N  +     G+N LI QV  LL  L+++G +     +  L+ P++ +LDG+ND+ F  +     +   +  ++ +    RFE S     +VDAK  GL VLE+L  FQ N R E  V  FK   A    N  ++K    ++ L  +++D  N  KK  ++ +     L+++  S+ YFD++ I  + LDL++YKY+ +L +SL  + K++SS+  +F  A   ++   ++S      I    P +  L    +N         +      +  L   P+   P  + QKIL +  ++D++F +  +E   +                   E    + L++G+ ++ L+ +A+    VQ  +  RL+ +M+++       ++L + +FA  ++  + + P  I  +      +++ AP+ L+L+  + +V+  +  ++ N   + K +M+ +       + S E++L + +    +  + + + L+ L+    E    ++ES  QT++ ++  +++ +    D  ++   L+++  +Y+K+         I +    L   R  W  +++           I E  VK ++ ++   P+       A+ + ++     +  + +  D V+PF+           + L       V      L++    V  ++     +  ++    S+L    I       + L+NY    SL+P  V+L  N         + +          +E + T+    + E +LN++F+ F  N   +  G N+  +Q+K+          S +EYT +   E LPLGEEFQ+ V+ F+  +E    KR+  +  +++ L +    +  K G        + D L+I   +ILRAV+ NE ++L EDW E   +  +  QL+ I  +Q+    ++  E VL H  R  + +  E  AFL ++ FNA+  VQ+ +  +F+ +  E+FFFA           IKE  A+        +E M   K L+ NL    K        ER + +++              R R+  LT+++     +C     +  K+    L+  TPL F S          ++E                       G+ +L++++L ++C+GQ   +QDY+R Q DN KS N+V  T   VN +Y+NI ++TI ++ Q+   LN+   GNQ NR+ L++ K++DYINFILR  ++ G   +  L+LR+++ANL+++L+EE+     ++A+E+  TVDK+A++  ++  Y               +  + P  K  I  ++   + NL  +    L+++      + +K++ Y++G+ Y  ++ RF DIDP ++   A   +T    AAY   KK   SIE++KD  +Q+VHFR+KN+ V+RE++ EK+KWDVDR+S ++K+RD   W+  ++ D+   +K   NP+ +F  + W LWNYL ILLS+ +N++ML ++K+   +       N+T       NP PD +   +  + +  +   H +FSL +LI+Y L + P   ++  + +   RLC
Sbjct:    1 MGEFLCIGDYISLFCEETEGYVYSYQTSSSHNGLYIYQGQDRKKPGKIPNPHAITFRVCIQNRYKLNKKYRKLLAASSKDPENLELKALVAQAKTSANAENQDNISEQKRQHGKRVRYGEIIQLKHVFTDKYVHISTTQTSHRDKNNMLISLHQYNGKHAQFRILPRYKVKSEGEYVQILDQIVYESFKSQGHYFHS----SVPWNIEKDMVGSELNLGVAQTGFTVVRYYRPSDENEANVRGSSFIRLFHKELEAYLVAEGLFGEPVQEEVHLRIREIDQLNPRTLSPPNSAITYWQVEPEDTILNGGVVRWEQQVRLRHVTTRRFLCLDADFEVCLTAEENDPRSVFRFHPVLSLREQDLDPDTPEQNEIDFESYCRIEHVLTGNWLHALKDEPYQRRRDMGRENDRSMQALRWDGGEVRKISSTENRRYVDVFTIHEVEWEQIYSANFVAGMVPFLSKLIESREECDYLNAMK-THQITTALQELKQFMIINGETYKDHQKLMRNFRIVDLLVQLLQSPLQDAPDSNYL--LSVFKEAYDILYTYMTGNSRKNALYFAKYIEFFQTQLSLKASTSVMIKQYHLVVVDPTLKGD-IGLNVAQMLVELIRDNRQIVDRITHEQIDIFVDLLRQRKNYRFLDLLNVLCVCDGKTILENQSYITETWLRHDKVSFDAKTCHIHLTGADVYLIERGQYIHKEHNVVYISTDAGHTWVPLHQFANADSPYYSEEEYLYLDRQLDLLGKLCKGRNQFSIRVITKDLDILTWENTFVCLRSELLPPSLRAKYCSLIIDLFVDVGASHSVLDQHTLVFVYEDIDNPRPLYSTKSQVATNVLFLAQELGTVFPVMRDWIQEFVESNPEMYSSQVGQNKLIEQVMRLLCYLVRFGCYCSADEIRILLKPLMIMLDGRNDRPFPKNAEIQNSKEVKKLVKQYRETDRFEKSAETKALVDAKYQGLSVLELLFTFQSNTRLESFVSKFKT--AETTANAKKKKHRSVLSPLVDDSYDAFNTSKKNLRKQKKFLHELRAMFESSSYFDVEYITNISLDLSNYKYEKMLTQSLNILNKYYSSKTDMFKIAIPTLVLTTQESCKIHIDIMRQLPLVRHLAKCSYNMEQAEAMSVVFDQFVLFTHLRDEPTLRHP--MNQKILINHGVLDLIFAILSQEVDVQIT-----------------EQAAPMELVFGKALNLLRFLAQGNEDVQAKMNDRLDSLMNIKLVPSHLAIAL-REVFAGNQNNCLKIQPKQILKIVHLAGENQDRAPEFLDLLGSIVKVELLELPLKRNQGLVMKYLMQNYHKAAYLFDQSQEDRLRILTSKTGNSHQRYLISLVDLLAKCAEGENRYIESLCQTIMPIEEIMDVLNNHFIDNNLKSPYLRYLMWVYMKTAGTM-----IESGAGDLPHDRHVWIYIQALAREAESLKTYISENEVKTVEVMRAPPPKG------AVAEMDDSDGAAHATLFYFFDAVLPFLQTFFTKFYSPDKELYPDELEYVDQLAHSLVLWCDRVGAVLCNATHLKVLIGCVPSVLQSSSIPKNLSTESALTNYP---SLKPKQVQLWKNTYKVMEGFIEQYGNGRCLRDPTRETIDTYTIYYQNEDELNKKFRAFSVNCSLVYGGHNTVTAQLKHK---------SKREYTEIGGDEDLPLGEEFQAHVRCFVKHNEKNIAKRYQNVSKLVQQLAVSANAVNPKDG------TYENDELDIKSLQILRAVIHNEERKLREDWEENTQDKKVQKQLKVILEVQNTLNSYSAVEEVLPHLGRPSNAIVRESLAFLSIMLFNANRNVQKAMLEYFMSTKKESFFFAIRCRLQLSAIAIKERRALATQHEARVKESMTQAKSLQTNLTVGRKAMKDIQAIERSRRQSRLMKGARANSLRALQRDRQSGLTSIS-PASSKCNSL--QRFKLPNGSLNEETPLVFGSNHNDIELNEVMVEGSDNLSVDVEEDDVLDGLEFKDEGYIVLVLRLLAAMCDGQNQSIQDYLRDQPDNIKSINVVADTAQFVNVVYSNITASTIDLVIQLFSTLNEFTAGNQANRVVLLDNKVVDYINFILRAGKYEGISMEMQLELREVIANLLVSLIEENGPEPIKVAREVKDTVDKEAVYRCMVDCY---------------SIHQPPTYKAKISTNMGDNMKNLSQMGGGLLREIMEKNKKNDLKDKAYEVGFLYFLLMARFYDIDP-VLNEKAGLVITPDQMAAYNYYKKNSMSIELMKDGNLQKVHFRVKNKNVLREEVKEKLKWDVDRSSPSNKIRDLMAWSKDILKDIYYQRKMLRNPIAVFFTKFWLLWNYLVILLSVAINVLMLWAWKAPYDM--SQAPENMTHLDHAIYNPNPDTSSVEIYDLLLYAMGGTHNLFSLFVLISYFLSNHPKCPSLSAIPNLCRRLC 2348          

HSP 2 Score: 160.229 bits (404), Expect = 5.743e-35
Identity = 99/281 (35.23%), Postives = 161/281 (57.30%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT--RNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTL 8001
            Y FAFHL+NI      L GV +AV Q+  S+ WVG+L +II Y + L+ F   R         YC TL  C  T+IR+G I   +  L +P+  S+ NF++   +++F +   I++  I LN+I GI+VD F+  R+LK +   DM + CFICSR S++FE    GF  H  +EHNMW+Y+++ I L   K +DYTAL  HV +  + +  +F+P++ AL+LT   +    + + + E    L+    E ++ ++  E+  R+++ ++  ++AL    +TL
Sbjct: 2401 YFFAFHLLNIVNNNQILQGVIKAVTQNGVSLLWVGILGVIIFYIYALISFAFMRALFLPKDEEYCGTLLECSVTVIRYGLIGAIFDRLTLPE--SENNFIAFAVVAVFHLSFFILITTIGLNVILGIVVDTFSELRDLKWTAESDMRDTCFICSRGSHDFEHHGNGFLKHAREEHNMWAYIFFFIHLDDTKSNDYTALDLHVAQALQREQYEFFPMNCALSLTGEEDGTDEKIDAVLEKVTELLRRQREEESKRMREEEHRRQKQWQEMYRKALSGSHDTL 2679          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Match: A0A210PSZ2 (Inositol 1,4,5-trisphosphate receptor type 1 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT13580 PE=4 SV=1)

HSP 1 Score: 688.337 bits (1775), Expect = 0.000e+0
Identity = 494/1753 (28.18%), Postives = 863/1753 (49.23%), Query Frame = 1
Query:  277 SMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXX------NMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSNNIHDPRTVLKFHPVNKDRDEFIRKGINVRVEHVISGRWLKVTPLITYTK---DEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIELF---GNLPVTAQMKWITPCQEIFSLINLY-IGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQ----EMHESFPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQLDILITGDWNHSALSNYRSILASIRAYCTLP-SCNIPNVVFQKILYSCNIVDILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCLKVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSL-IKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIP-DLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVES-------IKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFM---------------------TETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKE 5391
            S ++F++C+ +RYK++K+YRK +  D+   +S+     + K   A             N     R  G+++R+G+++QL+H+F+G F+H+++ + S+  K+  K  L  ++AK+AQF+I+P+YKV  EG  V +   + FES+ S  +YFH +   S+       G SE N+ ++++ F +        + +  + G +++  +H+E EAYL AEG F   I+E +H R+R ID    +SL+ ST+  TYW IE  +     D I W   IR++H  T  YL ++ K  + L+N+  DPRTV + H V K+RDE I+     R+EH+++G WL       Y +   +E        + WD AS   V+   +  YDDA+ I++V + +   F+   G  P + +L   +   T +N +  T     A+ E+   +  Q  P KNRQK+MR  ++ID L  +++     G+     +   I   +E + +++ Y IG + KN  Y AKY   F         I  +V  M+  +I    ++ +++   HI + +Q++  N NY FL  L   C    V I +NQ +I ++WL   K+ +Y++  G  I    N +Y+ST+  K+W  L+ F D     ++E   KF LHQLDL KA+  GRN     +IT +  Y+TW  A  C+  E++PD  RAK+CELII LF++ GN++ V+D+P   + Y  +G+     + H Q    ++   FP +R+W+  F+ QN  +   + G N LI QV  LL +L+K+GY+ D   + +L+ P+L++LDG +D  F     KG+T   +  +  +  + RF+ S+ N  I++AK   +EVL+ LL FQ N R +  V  FK        N   R     M + F  +   +  KK  +  + +   LK ++ S+  FDI+    VL DL+ Y YD ++ KSL  + K +SSQ  +F  A+   I    DS    + +Q   P L  L     N   ++    IL  +  +C LP +   P+ + Q IL S  ++  +  +  +E                  +K+  + +  +  ++ +T+D L ++ +E   +Q  +F+ L+ +  LE Q +   L+L +K +F   +   + V    I+ +      ++ +AP+ L L+  L +V+     I+ N   + K IM+ +       +   + +  + +   D     +F+ L+ L+    E   +F+ES  QT++ ++  L + +    D  +++  +K++  +Y+K   N      + +    L   +  WN V S       + +T  K  D++  +  Q      +A+    N G    ++  ++++ V+PF+                     TETL AQ  S       Q +   V      +  ++++ +IL  +      L+ +VL  +   + L                      K  ++ +  E++LN +F  F KN + +  G N+  +QIKY        + S +EYT+  T E L LGEEFQSLV+ F+++ E +P KRF     ++  L+  + + + + G          + L+I C +ILRA++ NE ++LPEDW    ++  I  QL YI+ +Q+A       E VL H +R    +  E+ AF+ ++ FNA+  VQ+ + +FF+ +  E FF A+++ + I    +K+ +R+L A+ + R+KE
Sbjct:   32 SAVVFQICIQNRYKLNKKYRKWQNTDNRENSSSTESPAVAKHSLALQARLAAEAENKDNEAEQTRQYGKRVRYGEVVQLKHIFTGKFVHMSTTQTSQKDKNNMKVSLHEFNAKNAQFRILPRYKVKSEGEVVQLFDQIVFESVKSHGHYFHASE--SFQIDHFTFG-SELNLGVERSSFTLIGCYREHADQERFVRGGSVIRLFHKELEAYLVAEGLFDDCITEDVHFRVRVIDQHRPKSLSASTSGITYWQIEAEHSILDGDVIRWEQQIRMRHLLTRQYLCIDSKMDVSLANDASDPRTVFRLHSVLKERDE-IQFESYARIEHMLTGCWLHALKDEDYDRRGMEENGERSMQGLRWDTASVRKVSASSESMYDDAYTIQEVVRLDTSNFNFVAGMVPFLFNLIQDLQLATQLNAKK-THGIIVALQELKNFMVPQGLPDKNRQKLMRNLRVIDILVNLLQCCLREGD----EESHMIRIFKEAYDVLHAYMIGKSRKNALYFAKYIDFFQTQFTQKGGIGLNVAQMIVELIRDKRKIVDRITKKHIDTFIQLLIKNHNYRFLDLLQVLCVCDGVAIPNNQSYIVEQWLRKYKASVYMMDRGQNINKRPNIVYVSTDGAKSWVPLNVFVDTEGPEFVEDDYKFLLHQLDLFKALCFGRNDFSGFVITREYGYLTWEDAYLCMTAEQLPDIIRAKYCELIIGLFVDVGNNYSVLDHPNICFVYEYVGSK-DAKVEHSQYVVMDLVTIFPVLRDWLAEFLRQNCQMTASDIGHNLLIEQVLRLLQHLVKFGYYLDIDDVKQLLTPLLSLLDGTHDVPFPKDKGKGYTKESQKLVTQYRSKGRFDSSKENEAIINAKYRAMEVLDFLLTFQRNLRLKAFVTKFKQCEQ----NLGHRTLEPLMYESFNPH---DQSKKVVRHQKQVLKELKEMVGSSSIFDIESTTSVLKDLSMYSYDKMVTKSLDILNKLYSSQSDMFQLASKAQILLTHDSAKVHREVQRSLPVLRRLAKQKLNDEQVTLTGEILDELAGFCHLPKNLEEPHFMNQNILVSHGVLPAILDILSQEID----------------AKLVDQQYKGMKTIFKKTLDLLALITRENSAMQEAMFNHLDTL--LEVQIVPSCLALALKELFIANQTTCLKVHSKQIQKIVLLAAQYQSEAPEFLELLKVLVKVEGLDLTIKRNQALVMKYIMQNFRKAAYVLDQPRDSREQILTNKRDPGHLAYFICLVDLLSTCAEGENKFIESLCQTIMPVEEILWVLNHRDIDGNLKQPFVKYMLWVYLKPAGNL-----VESGAADLQHDKEMWNFVASAADTIKQLSDTITKHRDRVALLLKQPPGKSAVAVPGDTNAGLHGCVF--YVLEAVLPFVEVFYSMFYSPDKDLYPGEIDTTETL-AQGLSSFCEVAGQFLTSPVH-----MKAIAASITILISVSTTNKSLYISVLERFSTEMRL--------------GDTKSAVRKGNMEYYAGELELNAKFHTFAKNNNIIYQGYNTVAAQIKY--------KKSKREYTAQGTNEELLLGEEFQSLVKCFIDVHERKPAKRFLPARILLEQLQ--ISQESIRQGLA------QTEELDIKCMQILRAIIHNEERKLPEDWDTCTSDQKIKKQLAYIKEVQNALNVHGFVEKVLPHVARRSDLIAREVLAFMSLMLFNANRDVQKSMLDFFLSTREEVFFMAVRDRMQISTNSIKE-KRSLLAQHQARVKE 1705          

HSP 2 Score: 248.054 bits (632), Expect = 1.232e-61
Identity = 154/483 (31.88%), Postives = 263/483 (54.45%), Query Frame = 1
Query: 5539 ENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELA------------KEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAIL---NLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKK--ANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGS----------------LIDETFSTNLTNPYPDFAHYPVLKIHMIYIST----------LHTIFSLCLLITYVLISKPGFNNIRQLKSYVERL-CQQLPVTDSAKSNK 6855
            ++G+  L++++L  LC+GQ   LQ+YMR Q DN KSFN+V  T   +N +Y+ INS TI ++ Q+   LN+   GNQENR  + + K++DYINFILR  E     P+++LDLR  +A+L+I L+EE+     ++A            KE+  T+DK A++  + Q ++  + D  P L+++   +  P   T  L S K       N  +   +  K+ +++KE + ++G+ +  IL R  DIDP +   +   D++ + + A+   KK   SIEI+KD+ +Q+V+FR+KN+  +R+++ EK+KW+VDRTS ++K+RD   W   ++ D+   ++   NP+ +   + W LWNY    LS+ +N++MLL++ +K +                L D +  + L+ P  +    PV +I  I + T           H +FSL +LI+Y L + P     +++   V  +  ++  V DS    K
Sbjct: 1844 DDGYIELVLKLLARLCDGQHCGLQNYMREQPDNVKSFNIVGETAQFLNVVYSTINSKTIDLIIQVFSTLNEFCSGNQENRFVIYDRKVVDYINFILRAGELADCDPEKILDLRQAIASLVIALIEENGPGKSQVAKQGKADELRYIHKEVKDTLDKNALYRCMTQCFEMHQADK-PKLDDV--LNNGPPGSTNYLKSAKSIAAFGGNFISGVMSGKKENASMKEMLMEVGFTFYLILARMIDIDPAMPERV---DISPEQRRAFDFYKKNSMSIEIVKDNILQKVNFRVKNKNYLRDEVKEKLKWNVDRTSPSNKIRDLMSWTRDIMKDISYQRRILHNPIAMLFTKGWLLWNYGATFLSVAINLLMLLTWNNKATEEDYAKLAEYGSTHAPLPDGSPGSTLSPPNWEVFKDPVPRISGISLDTYTILMYALGGTHNLFSLFVLISYFLSNHPSLPTCKEITDVVRGVFGKKEKVDDSGDQKK 2320          

HSP 3 Score: 170.244 bits (430), Expect = 5.149e-38
Identity = 107/274 (39.05%), Postives = 166/274 (60.58%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGE 7986
            Y FAFHL+NI      L+GV +AV Q+  S+ WV +L +I+IY + LV F L R+       LYC  L  C  T++R+G I D  M   + Q D + +F     + ++ V   I +  I LNII GIIVD F+  R+LK     DM + CFICSR+SY+FE   KGF +H+  EHNMW+Y++++I L  +K SDYTA++ +V+K+ + +N DF+P++RAL L+  +  + + K+ E  + + +I      NK  +E+ ++K++ EK K++   E
Sbjct: 2354 YFFAFHLLNIVNNNQLLSGVIKAVTQNGVSLLWVAILGMIVIYIYALVGFALLREFFTPGDYLYCTNLWQCTITVMRYGLIGD--MFETIHQTDLRNSFEYFWPLVLYHVSFFIFITTIGLNIIFGIIVDTFSELRDLKWRTESDMKDTCFICSRNSYDFEHTGKGFDHHVRNEHNMWAYVFFLIHLDDVKTSDYTAMELYVNKLMEEENYDFFPMNRALCLSTVDVDSTESKIDELLQQVTTI-----ANKQKQEEADKKRKVEKLKQKRWQE 2620          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Match: A0A267G7Y3 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011719g6 PE=4 SV=1)

HSP 1 Score: 659.833 bits (1701), Expect = 0.000e+0
Identity = 507/1937 (26.17%), Postives = 920/1937 (47.50%), Query Frame = 1
Query:  127 SQFLSFGDYIALYSEQDLGYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEAD-------------------DGSP-------------NSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLF---LSNNIHDPRTVLKFHPVNKDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSN-----EMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSL--KGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIELFGNLPVTAQMKWITPCQEIFSLINLY-IGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLH-QLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPITAYSYNNIG---------APY---------SPSIRHKQEMHES----FPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSF--NKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKEC-RSIETSLKSLM-SSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQLDILITGDWNHSALSNYRSILASIRAYCTLPSC-NIPNVVFQKILYSCNIVDILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCLKVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSL-IKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEM-SFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDL--LVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIK---ETNVKWL------DKLKQMSPQYQYDVLLAIRD---------AENLGDP------------------DYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKE----EIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRF---AKLINIIR----HLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLD-----NVTPLKFQSIIENGFGI 5556
            S F+  GDYI LY E   G++ + +S    N  FVY     D P N+P   +LLF+VC+ +RYK+DK+YRK   ++                   + SP             N  D    +++ ++AA+ E+ DNM   +RN+G+++R+G+I+QL+HVF+G ++H+N+N  S+  K+     L  Y++K+AQF+I+P+YKV  EG  V +   +S ES+ S  +YFH++             +SE N+ +++ GF + KS     + +    G   V  +H+E EAY+ AEG F  +++E +H+RIR+ID L+ R+L  ST++ TYW +E  +     + + W+   R +H +T  YL +   ++ +   L+ +  DP TV K HPV +D  E   +    R+EHVI+G WL      +Y + EF N      MR+ + WD      +T   D+RYDDA+ I+ V       F+   G  P ++ L    +I  P +  +   T     A+ E+   + +   P K RQK++R  ++ID L  +++ F    V  +        E + +++ Y +GN+ KN  Y AKY + F     + S +   V  ML  ++  + ++ +++    I+  ++++  N+++ +L+ L   C    V I  NQ+FIAQ+WL+ D  G+Y+   G  I    N  Y+S +   +W  L  F     Y     +   FLH QLDL  A+  GRN   I +IT    Y+TW  A   + +E +P +FRAK+CE+II LF+N GN++ V++ P   + Y  IG         +P           PS   +Q   +     FP IR+WI  F+ QN  ++      N LI QV  LL  L+K+GY+ +   L  L+  + N+LDG+ND  F       + F+   +  +  F    RF  S     IV AK+A L+VL++++ FQ N R    +  FKD+  + +    +RK    +     ++FD  + +K++ +  + ++  L+ +   S+++ D   +  +L+DL HY+YD ++  SL  + K  S++ ++F  A + ++    DS    + +    P L ++I   W         +IL+ +R  C LP     P+ + Q+++ S N++ ++F +   E   +    ++K H    +  +R            + +  +K +      VQN +F+ L+ ++ +  + +   L+L +K +F + ++L + + P  I  +   +  ++E AP+ L L+  + +V+     ++ N   + K IM+ +   G   E  + ++++++ +    +    + + L+ L+    E    ++ES  QT++S++  L + ++ P++   +++  L+++   Y+K+  +         D+      +L W  V  +    +   +W+      D +  MS +  +  +L + D         AE+   P                   +  + ++ D V+PF+         +      Q       +L +  + + S   +I+ +  I T     A LS   R  S  P I++            + T  +    +KE    EI LN + K    N   L  G+N+  +Q+KY          S++EYT +   E+LPL EEFQ  V+ F++    +P+ R+     L+N +R             AA A         D + L I   +ILRA + NE ++LPEDW   ++   +   L+ I  IQ+    F+L +  L H +     V  E+ + L ++ FNA+  VQ+ +  +F+ +  E FFFA++  L +   ++K+ R  ++ +   ++   +Q    + T+T + +    + + Y  E+ KI+++  D     ++T ++  SI +   G+
Sbjct:   24 SGFVCIGDYIGLYCEDTDGHVFSQNSCAAFNGLFVYHSCHRDRPVNIPDPQVLLFQVCIQNRYKLDKKYRKAVASNRQAAASAASQQQPQQQQTTETSPLTQPEQPEQQIAENDFDLRLHIEQARNAASAENVDNMAEQRRNLGKRVRYGEIVQLKHVFTGKYVHVNTNHTSQHDKNNMLLSLHEYNSKNAQFRILPRYKVKSEGEHVQLLDQISLESIKSPGHYFHSSKGFKIGPESRPTFVSELNLGVEQTGFTIIKSHGFSGDHEAYARGGQFVQLFHKELEAYVVAEGLFDQDVTEDVHLRIREIDQLNPRTLHSSTSAVTYWQVEPESTVLDGEVLTWDQQFRFRHATTRKYLCVKQASEAYSVTLTEDATDPHTVFKMHPVLQDSPELKFESY-ARIEHVITGCWLHAIKDKSYQRKEFLNMEDEKSMRA-LRWDGGELREITCCFDRRYDDAYTIQKVDSEHVMNFNFVAGVVPTLQDLIDARQIGRPLTSKE---TFRICHALRELRNFMLVNGEPCKARQKLLRNLRVIDLLVTLLK-FPLKAVQDEHNLTKVFSEAYDILHTYMMGNSRKNALYFAKYIEFFQTQMVDKSELALKVTKMLVELMKDNRKIVDRISNAQIEVFVELLRKNEHHSYLELLKVLCVCNGVAITENQNFIAQKWLLEDTRGVYMTNRGQNIDRKPNETYVSYDQQHSWLPLVDFVQPDEYDTEAVERCLFLHTQLDLFIALCHGRNEDCIRLITKDLSYLTWEEAYLGLSSESLPHEFRAKYCEIIIGLFVNVGNNYSVVESPQLCFIYEYIGTKDFTYQTSSPEQYKQGRKVGEPSRLEQQRAAKDLVTIFPVIRDWIAEFLDQNRMMVASQVANNILIEQVLKLLHYLVKFGYYGEVHDLARLLPALRNLLDGQNDIPFPPDRMPAREFSKERKKAVLRFKQTERFRRSPETQAIVRAKHAALQVLDLVMTFQENARLASFIKKFKDSEISEVAT--RRKHIHPLVPALYDSFDPFDTRKSALQVQKRMKKELRIMFEESSRHVDNIALTSILIDLAHYEYDPMVQLSLQLLNKLHSAKSSMFNLAVNSLVLITPDSCRVHREVGKQVPLLKMMIRSKWTSDQAVKIETILSELRELCHLPKAEEEPHPMNQRLMLSHNVLGVVFDILSTETDVQ---LTEKYH--ETVGVLR------------KAVRLMKALTIRYEDVQNQVFNNLDSMLRV--RLVEPDLALALKEVFVNNQELCLKILPRQISRIVGLVAENQERAPEFLELLSAIVKVEGPGLALKRNQTLVMKYIMQNYSKVGYVLEQCTTKDRMEVLNGNRGASHCQYLISLVDLLATCAEGENRYIESLCQTIISVEEILCILND-PNVENHLKKPFLRYMFYAYMKTSGSTAENR--SPDIIQDRYQKLVWEYVRHLTLEFDGLTRWIRNDAARDTVYFMSMR-PFPKILRLHDACPLCSTLVAEDETQPLKLNLENAVVRMREDDFRGHASLHYVFDAVLPFLQAFANKFYQTEEDKDTQSERDMFDRLTLSAIGLCSELAAIVVEPRILTQ--MVACLSALVRKSSHRPTIMEPVVENIGKGTKLQDTVSQMKSGNKEYYEQEIILNSKLKTLAVNMSLLWGGQNTVRAQLKYS---------SDREYTVIGGEESLPLDEEFQDHVRCFISAGSRKPEGRYRLAGLLVNGLRITAVSSTASASHAAAAAADPGAGGRGDTERLAIRILQILRAFIHNEERKLPEDWEVRMSEFRVKRGLKNIAEIQNTLNSFDLMKHALPHLASTSGLVAKEVLSLLGIMLFNANEKVQQSMLKYFLNTKEEVFFFAVRNRLQVSTANIKEKRLLISQQKARQMDARSQADDLKATMT-LGVKALQQIQQYHVEM-KIEQANSDLTRRVSLTQMQSASITKKKSGV 1916          

HSP 2 Score: 250.751 bits (639), Expect = 1.838e-62
Identity = 144/450 (32.00%), Postives = 256/450 (56.89%), Query Frame = 1
Query: 5530 SIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLI-----PSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKK--ANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDET---FSTNLTNPYPDF---------AHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQ 6822
            S+ ++G+  L+++VL  +C+GQ   LQ+Y+R Q DN KSFNLV      +N  Y+NINS TI +L Q+   +N+   GNQENR  + + KIIDYINFILRT++F   + DQ+  LR  +ANL+++L+EE++  A  + +E+  T+DK+A++ ++ + Y++ ++D+      L    KK E K                           +K+ I+D+G+ + +I+ R  DIDP +      P   E  ++     A+K  KK   +IEI+KD  +Q++HFR++N+ V+RE++ EK+KW+VDR SS++K+RDF  W  +++ D+   KK  +NP+ I + + W +WN+   L+++++N++ML+  ++     +      S + + P PD          A YP L   ++  + +    S+ +L+ + + + P   ++ +L   + +L Q+
Sbjct: 1985 SMKDDGYVGLVLKVLARICDGQHKGLQNYLREQPDNIKSFNLVAEVSQFINVAYSNINSETIELLVQLFTTVNEFCAGNQENRAAVYDNKIIDYINFILRTSDFENCELDQIASLRQAIANLVVSLIEENSPEAAVIGREVKDTLDKEALYRVMTECYEYCQRDSSGKEGWLRRLLKKDENK--------------------------ELKDAIFDVGFSFYTIIARLYDIDPAMGKKDSDPYGRELRISDSQMKAFKFFKKNSMTIEIVKDSNLQKIHFRVRNKNVLREEVKEKLKWNVDRNSSSTKIRDFMDWTKAILNDIHYQKKVLSNPLTIALTRLWLIWNHSATLVAVIINLIMLIGLEAPPGGANTPSLDISADESAPVPDAFFNTTGQWKADYPSLPDWLMAFAYILDALSIIILLAFFVANHPRPPDLARLAWRLRQLRQK 2408          

HSP 3 Score: 178.718 bits (452), Expect = 1.383e-40
Identity = 112/313 (35.78%), Postives = 178/313 (56.87%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNL-YCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFI 8100
            Y FAFHL+NI      L GV QAV  +  S+ WV +L + I+Y + ++ F  FR A     +L +C TL  C+ T++RFG I D +  L  P   S +NF   V+M++F++   ++++ I LNII GIIVD F+  R+ K     DM N CFICSR++Y+FE   +GF +H+  EHNMW+Y+++ I L     +DYT+L  HVHKM K +  +F+P++RAL L+  +E + D K+ E    +  ++      +  R +     RQ+KW+++ L  G     ++ T  +   +++ S  +  R   PA +  F+
Sbjct: 2453 YFFAFHLLNIVNNNQMLRGVIQAVTTNGLSLVWVSVLGIAIMYLYAVIGFAKFRIAFRPDDSLMFCGTLYQCFVTILRFGLIGDLFENLVPPS--SHRNFDEYVWMALFSITFFVLISTIGLNIIFGIIVDTFSQLRDKKWMAETDMRNCCFICSRNNYDFEHHGQGFDHHVRTEHNMWAYIFFFIHLEDTATNDYTSLDLHVHKMLKEERFEFFPLNRALCLSAKDEDSTDSKIDELLSNVKDLVQHQKEEEAERRRWVELNRQKKWQQKVLSSGH---LLQDTAALAAASESGSGGVRIRGSHPAPDRRFL 2760          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192])

HSP 1 Score: 114.39 bits (285), Expect = 1.660e-24
Identity = 207/934 (22.16%), Postives = 388/934 (41.54%), Query Frame = 1
Query:  127 SQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETE----PGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSN----------------NIHDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPT-SMNDESLTRYFTEA----IGEISKN-----LCIQNNPTKNRQKMMRTTKLIDWLFQIIEL-FGNL---PVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTL-----------------YISTNA---GKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAPYSPSIRH---KQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD-GKNDKKFRSSFNKG 2700
            S FL  GD ++LY+E  + G++   S+  ++++  V   ++ DL          LF+VC  +RY   K++ K K+   G        D  KKL+ AA LE K N    K+ +G  +++  +IQL H+ S  ++ +N    + ++K+A +  L P   + + F I P +K+  EG  V +G  V              N       S  E    PG +E N       + V           ++L G ++V  +H E E +LT + Y      ++ H+ +R      +R S T +T+S   W +E  +  P       WN + R KH +TG YL    ++    S                 + +D  ++ +       R D  + +   VR+ ++ +  W      +T T +   +E    V+       T    +D+   +AF I  V   E +          ++++   K+   T + ND        E     + E+  N       + +NP + RQK+MR   ++  +F I++  F +    P+           A  K++   Q  + ++     +  KN +Y+AK F I    +     +  D IT L H   ++ ++ EK +    I++ ++++  N+   FL +LS  C S    I   Q+ I + +++N  +   L+Q    I    N++                 +I  N    GK+   L+      H L I+    ++  QL+L   +   R    I  I+T+   +   + + C+ ++ +P + RA FC L++ + ++      V+  P+  A  +N I  P   S++    + +M   F    +++  ++    +    + +  +N L ++V  L  NL+ +G++   S L  L   +L +LD  ++   F S  +KG
Sbjct:    6 SSFLHIGDIVSLYAEGTVNGFI---STLGLVDDRCVVQPEAGDLANPPKKFRDCLFKVCPMNRYSAQKQFWKAKQGKQG---GNTEGDLFKKLQHAAELEQKQNETENKKLLGEVVKYSQVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDPSGNEGSWFYIQPFWKLRSEGDNVVVGDKVVL---------MPVNAGQPLHASNIELLDNPGCNEVNAVNCNTSWKVTLFMKFSDYKDDILKGGDVVRLFHAEQEKFLTCDDY-----KDQQHIFLRTT----LRQSATSATSSKALWEVEVVHYDPCRGGAGQWNSLFRFKHLATGKYLAAETESDAVYSKKKRPVEKITYILVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRNLCTNTW------VTSTNNSIDHEEERPVMLKIG---TCPTKEDK---EAFAIVSVPLSEVRDLDFANDANKVLEAFVRKLEKNTFAQNDRRFVIKLLEDLVFFVCEVPNNGQDVLSVVISNPNRERQKLMREQNILAQIFGILKAPFADREDGPILKLEDLGDQRYAPFKYML--QLCYRILRHSQQDYRKNQEYIAKKFSIMQS-QIGYEILAEDTITALLH---NNRKLLEKHITAREIETFVKLLRRNREPRFLDYLSDLCVSNKTAIPVTQELICK-FMLNPTNADILIQ-TKLIPHTENSMDSSLMHEEGDEEEVWLYWIDHNKEPHGKSIRHLAQDSKGNHKLDIDI-ITYYRCQLNLFAKMCLDRQYLAINQISTQ---LPVDLILRCMFDDCLPYNLRASFCRLMLHMHVDRDPQEAVV--PVRYARLWNEI--PSKISVKEDTSRADMKRKFAPTMDFVDEYLKDVLSQPFPFGDEEKNELTLEVVNLARNLVYFGFY-SFSELLCLTRTLLAILDIVQHPLTFMSKLSKG 886          

HSP 2 Score: 83.1889 bits (204), Expect = 4.665e-15
Identity = 70/247 (28.34%), Postives = 122/247 (49.39%), Query Frame = 1
Query: 7156 VAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRD----------AMNMSSNL----------YCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            V  + ++  L ++      L  V ++V ++  S+    +L +I++Y F++V F+  +           A++++  +           C+TL  C  T++  G      +   L  P  D       VVY  +F  +    V II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW YLY+++ +R    ++YT  + +V +M K KNLD++P  +A++L
Sbjct: 2238 VHEFFYSILLFDLVRREETLLNVMRSVTKNGRSIFLTAVLAIILVYLFSIVGFLFLQSDFLMEVDRHPALDLTCKVEKSDEPEMERVCETLLMCIVTVLNHGLRNGGGIADILRKPSKDEPMFAARVVYDLLFFFI----VIIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVSFEEHIKVEHNMWHYLYFLVLVRVKDPTEYTGPESYVAQMIKEKNLDWFPRMQAMSL 2480          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Match: ryr1b (ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:ZDB-GENE-070705-417])

HSP 1 Score: 93.9745 bits (232), Expect = 2.758e-18
Identity = 67/225 (29.78%), Postives = 116/225 (51.56%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----LYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   NMS +     + CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +Y+++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4727 FFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNMSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYE-----LYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4943          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Match: ryr1a (ryanodine receptor 1a (skeletal) [Source:ZFIN;Acc:ZDB-GENE-020108-2])

HSP 1 Score: 92.4337 bits (228), Expect = 7.862e-18
Identity = 67/225 (29.78%), Postives = 115/225 (51.11%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----LYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   N S +     + CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +YL++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4707 FFFACHLLDIAMGVKTLRTILSSVTHNGKQLMMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDENEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYE-----LYRVVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4923          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Match: ryr3 (ryanodine receptor 3 [Source:ZFIN;Acc:ZDB-GENE-041001-165])

HSP 1 Score: 87.8113 bits (216), Expect = 2.006e-16
Identity = 65/225 (28.89%), Postives = 114/225 (50.67%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----LYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + FA HL++IA+    L  +  +V  +   +     L+ +++Y +T+V F  FR   N S +     + CD +  CY       +   G I D   E+  P  D  +     +Y  +F +     V +I+L II G+I+D F   R+ ++   +DM   CFIC   +  F+T   GF  H L+EHN+ +YL++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4473 FFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDPYE-----LYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4689          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Match: itpr1a (inositol 1,4,5-trisphosphate receptor, type 1a [Source:ZFIN;Acc:ZDB-GENE-070604-3])

HSP 1 Score: 84.7297 bits (208), Expect = 1.498e-15
Identity = 86/305 (28.20%), Postives = 146/305 (47.87%), Query Frame = 1
Query: 7162 YYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLY-------------------------CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEID--TNKLH--REQLNRKQRQEKWKKEALG 7983
            Y L  F L+N       L  V ++V ++  S+    +L LI++Y F++V ++ F+D   +  N                           CD+L  C  T++  G      +   L  P  +       V+Y  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI +EHN+W YLY+++ +R    ++YT  + +V +M K  NLD++P  RA++L  ++   E  +L+   E L S +  +   TN+L   +EQ+  +QR+ K +   LG
Sbjct: 2322 YSLLLFDLVNRE---ETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSIVGYIFFKDDFILEVNRIPNRNINVCVFGMLCPFVCADDVERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFLV----IIIVLNLIFGVIIDTFADLRSEKQRKEEVLKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLYFIVLVRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRCLQEKLESTMRLVSNLTNQLTELKEQMT-EQRKHKQRIGLLG 2618          

HSP 2 Score: 73.559 bits (179), Expect = 3.868e-12
Identity = 127/563 (22.56%), Postives = 229/563 (40.67%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNP-NPSYPRSET------EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTL----NYKNKLFLSN-----------------------------NIHDPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTR------YFTEAIGEISKNLC--IQNNPTKNRQKMMRTTKLIDWLFQIIE 1638
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF +C  +RY   K++ K   A      S      L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V              NP N   P   +       PG +E N V+   +  IV   +  D     L  G  +V  +H E E +LT + +      +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL      +Y+ +   S                              + +D  ++ +  P   +  D  + +   VR+ H+ +  W+  T      ++E    +R           T  + +D+   +AF I  V+  E +        + ++ S+ GK+   T   +E  ++T+      YF   I   ++++     N P + RQK+MR   ++  +F++++
Sbjct:    1 MVDKMSSFLHIGDICSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQKQFWK---AAKPGGTSTTDTVLLNKLHHAADLEKKQNESENKKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVL------------NPVNAGQPLHASGHQLVDNPGCNEVNSVNCSTSWKIVLFMKWSDNQEVVLKGGD-VVRLFHAEQEKFLTCDDH-----RKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECLESRSSVSVCLLYTQLWKKLRDHFIMYTLVSVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNHPIDKEEEKPVMLR---------IGTSPLKEDK---EAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRAVTKLLEDLVYFVVDIPNSAQDVLEITVNKPNRERQKLMREQNILKQIFKLLQ 524          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007822.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007822.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.2478 bits (173), Expect = 1.595e-12
Identity = 33/97 (34.02%), Postives = 58/97 (59.79%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRS--SYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT 7833
            +D FA  R+ K  K + +   CFIC+      +F+ K   F  HI  EHNMW+YLY+++ ++    ++YT  + +V +M + +N+D++P  RA++L 
Sbjct:  308 IDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSLV 404          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007816.1 (pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-1 gene:ENSPMAG00000007060.1 transcript:ENSPMAT00000007816.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.633 bits (174), Expect = 2.517e-12
Identity = 33/96 (34.38%), Postives = 58/96 (60.42%), Query Frame = 1
Query: 7549 VDKFATARNLKDSKYDDMINYCFICSRS--SYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            +D FA  R+ K  K + +   CFIC+      +F+ K   F  HI  EHNMW+YLY+++ ++    ++YT  + +V +M + +N+D++P  RA++L
Sbjct:  763 IDTFADLRSEKQKKEEVLKTTCFICAAGLERDKFDNKTVSFEEHIKVEHNMWNYLYFIVLIKVKDPTEYTGPESYVAQMIREENVDWFPRMRAMSL 858          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003582.1 (pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 gene:ENSPMAG00000003274.1 transcript:ENSPMAT00000003582.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 66.2402 bits (160), Expect = 4.907e-11
Identity = 66/280 (23.57%), Postives = 118/280 (42.14%), Query Frame = 1
Query:  286 LFEVCVCHRYKMDKRYRKL-KEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTN----PNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLT 1107
            LF +C  +RY   K++ K  K A   S +S                 + +N    K+ +G  +++G+++QL H+ S  ++ +N    + ++K+A + VL     + + F + P YK+   G  V +G  V    + +      +N     NP      +    + + +SL    F+ +     D           +V  +H E E +LT++ Y      +K H+ +R       +S T +T+S   W IE   + P       WN + R KH +TG YL 
Sbjct:   38 LFRMCPMNRYSAQKQFLKAAKPAIHSSTDSLLLKKLQHAADLEKKQNESEN----KKLLGTVIQYGNVVQLLHMKSNKYMTVNKRLPALLEKNAMRVVLNGSGNEGSWFYVQPFYKLRSMGDSVVVGDKVVLNPVNAGQPLHASNYELVDNPGCKEVNSVNCSTSWKISL----FMTWSENKEDILKGGD-----VVRLFHAEQEKFLTSDEY-----RKKQHVFLRTTGR---QSATSATSSKALWEIEVVQHDPCREGAGHWNSLFRFKHLATGDYLA 296          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Nematostella
Match: EDO37876 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEK1])

HSP 1 Score: 140.198 bits (352), Expect = 9.299e-33
Identity = 232/1121 (20.70%), Postives = 462/1121 (41.21%), Query Frame = 1
Query:  127 SQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLTLNY---------KNKLFLSNNI---------HDPRTVLKFHPVNKDR-DEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKI--SNPTSMNDESLTRYFTEAI---------GEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVTAQMKWI----TPCQEIFSLINLYIGNNS----KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYL------------LQDGS-AIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIE--SQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQNSSLI--YENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD------------GKND------KKFRSSFNKGFTMMER---------DELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFK----DTRAAVM-VNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDI-----QRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVF 3159
            + FL  GD ++LY+E ++ G++   S+  ++++  V    + DL          LF++C  +RY   K++ K  +    + ++          +         N    K+ +   +++G ++QL HV S  F+ +N    +  +K+A +  L P   + + F IVP YK+   G  V +G  V    + +      +N           PG  E N    +  + +    S D+N +++L G ++V  +H E E +LT + +      +K ++ +R       ++ T +T+S   W +E   + P       WN + R KH +TG YL             ++KL  S+ +         +D  ++ +  P    R D  + +   VR+ H+ +  W+  T +     +E    ++           T ++ +D+   +AF I  V   E +        + ++ +   K+   N T      +T+  T+ +         GE   N+ +Q +P ++RQK+MR   ++  +F +++      GN P+    +       P + IF L    + ++     KN +Y+AK F  F   +     +  D IT L H   ++ ++ EK +  T I++ + +V   +   FL +LS  C S    I + Q+ I +  L    S L +            + +G   + G+   +++    G+              +  E      ++ +QL+L   +   R    I  I+   K +   + + C+ ++E+P D RA FC L++ + ++           Y   +  +   +T + Y+     +      ++++   F  + +++ N++   SS +  + +  +N L  +V  +  +LI +G++   S L  L   +L++LD            GKND      +  +S    G TM              +Q     ++ E+ E ++V+++ K   +E+LE ++  +L+ R   L+ +FK    ++ A +  VN D                D+ NI   S +  +I     S+ S+    D+     +    VLL L  + Y SL+  SL  + + FS ++ V 
Sbjct:    5 TSFLHIGDIVSLYAEGNVTGFI---STLGLIDDRCVVQPGAGDLSNPPKKFRDCLFKICPMNRYSAQKQFWKAAKPTTSATDAVLLKKLHHAAELEKKQ----NESEYKKMLSSVVQYGSVMQLLHVKSNKFLTVNKRLPALREKNAMRVTLDPNGNEGSWFYIVPFYKLRAAGDNVVVGDMVILNPVNAGQPLHASNQELI-----DNPGCKEVNCVNCQTSWKISLFLSYDENDEDILKGGDVVRLFHAEQEKFLTCDDF-----KKKSYIFLRTTAR---QTATSATSSKALWEVEVVQHDPCRGGAGHWNCLFRFKHLATGDYLAAEADDDNTKDATRHKLKGSDPVFHLVPAPHGNDIASIFELDPTTLTRSDSLVPRCSYVRLRHLCTNTWVHSTGIPIDKGEERPVMLK---------IGTASIKEDK---EAFAIVPVPALEVRDLDFANDASKVLGTFASKLETGNYTQHERRFVTQLLTDLVYFVTEHDTGGEDVLNIQVQ-DPNRDRQKLMREQNILKEVFHLLKAPFTDKGNGPMLRIEELSDQRNAPLRHIFRLCYRVLRHSQQDYRKNQEYIAKQFG-FMQAQIGYDILAEDTITDLVH---NNRKLLEKHITRTEIETFVSLVRKKKECRFLDYLSDLCVSNHTAIPATQELICKTVLHPSNSDLLIETSMGDVLLVWEMNNGKRCVPGLGEYVFLVWERGEKMKAQKDIAKGVKMMVKEDIKILDYYRYQLNLFSQMCLDRQYLAINSIS---KQLDVDLILRCMADKELPCDLRAAFCRLMLHMHIDRDPQETVTPVKYARLWSEIPTEMTIHVYDQ----HEAVGEEREDIRRRFEGVIQFVENYLHNISSNVFSFSDKEQNKLTFEVVQIARHLIYFGFY-GFSDLLRLTQTLLSILDCEQRAFTRIHNGGKNDVNDNKVEMTKSIHLLGATMTRVAFGGSLDPWGLIQHSEGGTKGEI-EIDHVVMETKLKVIEILEFIMNVRLDYRISSLLTIFKKDFDESNANIGDVNADN-------------GIDLENI---SAQAEAIFGG--SIGSADIDLDLDGQGGRTFLRVLLYLCMHDYPSLVTGSLQLLIRHFSQRQEVL 1061          

HSP 2 Score: 96.2857 bits (238), Expect = 2.131e-19
Identity = 75/244 (30.74%), Postives = 125/244 (51.23%), Query Frame = 1
Query: 7156 VAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----------------LYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSK-KNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT 7833
            V  + ++  L+++      L  V ++V ++  S+   G+L LII+Y F++V F+  +D   + ++                   CDTL  C  T +  G      +   + +  SK K F   V   ++ +M   IV II+LN+I G+I+D FA  R+ K +K + + N CFIC      F+ K+  F  HI  +HNMW YLYY++ LR    +++T  + +V  M K KNLD++P  +A++L 
Sbjct: 2315 VHTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKMFAGRV---VYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLA 2555          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Nematostella
Match: EDO28592 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T616])

HSP 1 Score: 91.6633 bits (226), Expect = 2.509e-18
Identity = 75/256 (29.30%), Postives = 125/256 (48.83%), Query Frame = 1
Query: 7156 VAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----------------------------LYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSK-KNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT 7833
            V  + ++  L+++      L  V ++V ++  S+   G+L LII+Y F++V F+  +D   + ++                               CDTL  C  T +  G      +   + +  SK K F   V   ++ +M   IV II+LN+I G+I+D FA  R+ K +K + + N CFIC      F+ K+  F  HI  +HNMW YLYY++ LR    +++T  + +V  M K KNLD++P  +A++L 
Sbjct:  451 VHTFFYSVLLLDVIFREDTLLNVIRSVTRNGRSIILTGILALIIVYMFSIVGFLFLKDDFLIETDPPPALPSIGSPRGGVCASSGGEGGESVKERACDTLIMCIVTTLNQGLRNGGGIGDVLRRRSSKEKMFAGRV---VYDLMFFFIVIIIVLNLIFGVIIDTFADLRSEKQNKEEVLKNTCFICGLDRSAFDNKSVSFDEHIKSQHNMWHYLYYIVLLRVKDPTEFTGPESYVSHMTKDKNLDWFPRMQAMSLA 703          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Match: itpr1b (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101155104])

HSP 1 Score: 128.642 bits (322), Expect = 7.850e-29
Identity = 241/1149 (20.97%), Postives = 462/1149 (40.21%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLT------LNYKNKLFLSNNIHDPR-----------------TVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMR---SQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEI---------SKNLCIQ---NNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQ----DGSAIGGIA---------------NTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFIFQ--NSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLD-----GKNDKKFRSSFNKGFTMM-----------ERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSS-QETVFTTATDMMITHGKDSDSWLKMIQDF 3231
            + +  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF++C  +RY   K++ K   A     NS      L KL  AA LE K N    ++ +G  +++G++IQL H+ S  ++ +N    + ++K+A +  L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  +V   +  D     L  G  +V  +H E E +LT + +      +K H+ +R       +S T +T+S   W +E  +  P       WN + R KH +TG YL          +N   L   +  P+                 ++ +  P   +  D  + +   VR++H+ +  W+  T      ++E    +R   S+V  D  +F  V +   +  D  F   D +K              ++ S+ GK+   T   +E   R+ T+ + ++         S    ++   N P + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S    I   Q+ I    L ++ + + +      + S  G I                N   I + + +   Q +    K      +    ++  QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC L++ + ++           Y   +  +   I    Y+N G         + E+ E F    +++ N++ +  + ++ + +  +N L  +V  L  NLI +G++ + S L  L   +LN+LD     G N  K      +  T +              + +    +++ E    + +++D K   +E+L+ +L  +L+ R   L+ +FK        N    +           NFD  NI++ ++       S ++          +    VLL LT + Y  L+  +L  + + FS  QE +       ++   +D D++ ++  D 
Sbjct:    1 IMDKMSSFLHIGDICSLYAEGSTSGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWK---AAKPGGNSTTDTVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSLGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKVVLFMKWSDNKETILKGGD-VVRLFHAEQEKFLTCDDH-----KKKQHVFLRTTGR---QSATSATSSKALWEVEVVHRDPCRGGAGYWNSLFRFKHLATGCYLAAEVNPDFEEENNEALRGRLRTPQEKVMCTLVPVPDGMEISSIFELDPTTLRGGDSMVPRSSYVRLKHLFTNTWVHSTNNPIDKEEEKPVMLRIGTSEVKEDKEAFAIVPVPPAEVRDLDF-ANDASK--------------VLASIAGKLEKGTITQNER--RFVTKLLEDLVFFVVDIPNSGQDVLEIMVNKPNRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVTLVRKNREPRFLDYLSDLCVSMSKSIPVTQELICNAVLDSNNADILIETKFEIETSTNGDIPLQAEDEEEVWLFWKDNAKDIRSKSVRELAQDAREGQKED----QEVVSYYRCQLNLFARMCLDRQYLAINKISNQ---LDVDLILRCMSDEDLPFDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSKIAIDDYDNDG-------NSRDEIKERFSLTMDFVENYLREVVSQNIPFTDKEKNKLTFEVVNLARNLIYFGFY-NFSDLLRLTKILLNILDCVHVTGSNVMKSIHGVGELMTQVVLRGGGLLPTAPAHQPEGEVVKTQTEPEREDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFK---CEFDENNPPGENAPNQIPSLTGNFDFENIEEQAEGI--FGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQLLVTSQDVDNYKQIKSDL 1083          

HSP 2 Score: 77.7962 bits (190), Expect = 2.309e-13
Identity = 68/268 (25.37%), Postives = 121/268 (45.15%), Query Frame = 1
Query: 7156 VAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRD------------------------AMNMSSNL-----------------YCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALAL 7830
            V  + ++  L ++      L  V ++V ++  S+    +L LI++Y F++V ++ F+D                         + +SS                    CD+L  C  T++  G      +   L  P  +       V+Y  +F  M+     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW YL++++ ++    ++YT  + +V +M +  NLD++P  RA++L
Sbjct: 2297 VHVFFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILAVDRIPNKTLGTTEAHFQLNTLTLSSQPCPKLSFHPSVVIEDKERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMV----IIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKVEHNMWHYLFFIVLVKVKDSTEYTGPESYVAEMIREHNLDWFPRMRAMSL 2560          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Match: itpr1a (inositol 1,4,5-trisphosphate receptor type 1 [Source:NCBI gene;Acc:101167700])

HSP 1 Score: 115.546 bits (288), Expect = 6.965e-25
Identity = 236/1159 (20.36%), Postives = 459/1159 (39.60%), Query Frame = 1
Query:  112 VTNDFSQFLSFGDYIALYSEQDL-GYLAADSSSQILNEPFVYSRQSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSXXXXXXXXXXXXXXXXXXXXNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSET---EPGISEFN-VSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPSTNSNTYWVIEKA-NVPYSMDPIAWNDMIRLKHGSTGFYLT--LNYKNKLFLSNNIH-------------------------DPRTVLKFHPVN-KDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDE--SLTRYFTEAI---------GEISKNLCIQNNPTKNRQKMMRTTKLIDWLFQIIEL----FGNLPVT----------AQMKWITPCQEIFSLINLYIGNNSKNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQ--------EWLVNDKSGLYLLQ-DGSAIGGIA-----------------NTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLN-----------YGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREWIGNFI--FQNSSLIYENTGRNHLIIQVFYLLLNLIKYGY--FDDTSSLHELIDPILNVL--------------DGKNDKKFRSSFNKGFTMMERDELQDFHY--------------RSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRS------IETSLKSLMSSTQY---FDI-----QRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVF 3159
            +++  S FL  GD  +LY+E    G++   S+  ++++  V    + DL          LF++C  +RY   K++ K        P        L KL  AA LE K N    K+ +G  +++G++IQL H+ S  ++ +N    + ++K+A + +L     + + F I P YK+   G  V IG  V    + +          P +  S      PG +E N V+ + +  IV   +  D     L  G  +V  +H E E +LT + +      +K ++ +R       +S T +T+S   W +E   + P       WN + R KH +TG YL   +N + +    +N H                         D  ++ +  P   +  D  + +   VR+ H+ +  W      +  T      E    V+      + +     +   +AF I  V+  E +        + ++ S+ GK+   T   +E  ++T+   + +         G+    + + N   + RQK+MR   ++  +F++++      G+ P+           A  + I  C+  + ++     +  KN +Y+AK F+ F   +     +  D IT L H   ++ ++ EK +    I + + +V  N+   FL +LS  C S +  I   Q+ I          + L+  K  L   +  G  +G  +                 N   I + + +   Q +    K     I     ++ +QL+L   +   R    I  I+ +   +   + + C+ +E++P D RA FC +++ + ++           Y   +  +   I+   Y+N G         K E+ E F    E++  ++    + +L + N  +N L  +V  L  NLI +G+  F D   L +++  IL+ +              D K     RS    G  +M +  L+   +              +++ E  + + +++D K   +E+L+ +L  +L+ R   L+ +FK               T+F  +  Q +  IN + ++    +       +E   + +   ++     D+     +    VLL LT + Y  L+ ++L  + + FS ++ V 
Sbjct:    1 MSDKMSSFLHIGDICSLYAEGSTNGFI---STLGLVDDRCVVQPDAGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKA-----AKPGGNTDTVLLNKLHHAADLEKKQNDSENKKLLGSVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVMLDTAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNA--------GQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWGDNQEVVLKGGD-VVRLFHAEQEKFLTCDDH-----RKKQYVFLRTTGR---QSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPEYEEERPDNQHEALRARLRCAQEKVMYALVAVPDGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTW------VHSTNQPIDKEEEKPVM------LRIGTSPHKEDKEAFAIVPVSPAEVRDLDFANDASKVLASIAGKLEKGTITQNERRAVTKLLEDLVFFVVDIPNNGQDVLEIMV-NKHNRERQKVMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHI--CRLCYRVLRHSQQDYRKNQEYIAKQFR-FMQKQIGYDVLAEDTITALLH---NNRKLLEKHITAAEIDTFVNLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFEIQGVPLGENSVESEEDEEEVWLFWKENNKKEIRSKSIRELAQDAKEGQKEDKEVI----SYYRYQLNLFARMCLDRQYLAINKISCQ---LDVDLILRCMSDEDLPFDLRASFCRMMLHMHVDRDPQEQVTPVKYARLWSEIPLKISIEDYDNDGTS-------KDEIKERFSQTMEFVETYLRNVVSPNLSFGNKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLGILDCVHVGAIYSFNKQEKEDSKGSNVMRSIHGVG-ELMSQVVLRGGGFLPTTTVNTSNGEAVKTQIEPEKQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFK---------------TEFDERNSQSDLSINGVIESQNNMQGALDFEHMEEQAEGIFGGSEQNNPLDLDDHGGRTFLRVLLHLTMHDYPPLVSRALHLLFRHFSQRQEVL 1085          

HSP 2 Score: 80.8777 bits (198), Expect = 2.321e-14
Identity = 68/266 (25.56%), Postives = 123/266 (46.24%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRD--------------------------------AMNMSSNLY---------CDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALT 7833
            + ++  L ++      L  V ++V ++  S+    +L LI++Y F++V ++ F+D                                  N S+ ++         CD+L  C  T++  G      +   L  P  +       V+Y  +F  M+     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI++EH+MW YLY+++ ++    ++YT  + +V +M K  NLD++P  RA++L 
Sbjct: 2337 FFYSLLLFDLVYREETLLNVIKSVTRNGRSIVLTAVLALILVYLFSIVGYIFFKDDFILEVDRIPNITLSADDADGELLSAVCHNGAGENCSTAVHEEDSNMERTCDSLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMV----IIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVTFEEHIMEEHSMWHYLYFIVLVKVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLV 2598          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Match: itpr2 (inositol 1,4,5-trisphosphate receptor, type 2 [Source:ZFIN;Acc:ZDB-GENE-050419-192])

HSP 1 Score: 81.6481 bits (200), Expect = 1.280e-14
Identity = 76/302 (25.17%), Postives = 139/302 (46.03%), Query Frame = 1
Query: 7156 VAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN------------------------LYCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALG 7983
            V  + ++F L ++      L  V ++V ++  S+    +L + ++Y F+++ F+  +D   M  +                          CDTL  C  T++  G      +   L  P  +       VVY  +F  ++     II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHNMW YLY+++ ++    ++YT  + +V +M   KNL+++P  RA++L  NE   E  +++   E L + +  I        +L  +  +++  K+ +G
Sbjct: 1277 VHEFFYSFLLFDLVSREETLLNVIKSVTRNGRSIFLTAVLAIFLVYFFSIIGFLFLKDDFRMEVDPLPLPGHPSQDTCLCERCEDDGMERVCDTLLMCIITVLNQGLRNGGGVGDILRRPSKEEPLFAARVVYDLLFFFVV----IIIVLNLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKSEHNMWHYLYFLVLVKVKDPTEYTGPESYVAQMIAEKNLEWFPRMRAMSLVSNEGDNEQNEMRSLQEKLTNTVTLISQLSSQLAELKEQMTEQRKNKQRMG 1574          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Match: ryr1b (ryanodine receptor 1 [Source:NCBI gene;Acc:101160087])

HSP 1 Score: 80.8777 bits (198), Expect = 2.686e-14
Identity = 61/225 (27.11%), Postives = 112/225 (49.78%), Query Frame = 1
Query: 7165 YLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSN-----LYCDTLGHCY-----TTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYP 7809
            + +A HL++IA+ V  L  +  +V  +   +     L+ +++Y +T+V F  FR   N S +     + CD +  CY       +   G I D   E+  P  D  + +  V  ++ F  ++      ++L  I  +I+D F   R+ ++   +DM   CFIC   S  F+T   GF  H L+EHN+ +Y ++++ L +   +++T  + +V KMY+ +  DF+P
Sbjct: 4449 FFYACHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGD---EIEDPAGDEYELYRVVFDITFFFFVI------VILLAIIQLIIDAFGELRDQQEQVREDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANY-FFLMYLINKDETEHTGQESYVWKMYQERCWDFFP 4663          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Match: itpr3 (inositol 1,4,5-trisphosphate receptor type 3 [Source:NCBI gene;Acc:101170574])

HSP 1 Score: 79.7221 bits (195), Expect = 5.251e-14
Identity = 71/240 (29.58%), Postives = 125/240 (52.08%), Query Frame = 1
Query: 7288 IYAFTLVIFVLFRDAMNMS----SNL--YCDTLGHCYTTLIRFGFIFDKWME--LFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALG 7983
            +Y F++V F+  ++   M     SNL   CDTL  C  T++  G      +   L  P  D +  F + V   ++ ++   IV II+LN+I G+I+D FA  R+ K  K + +   CFIC     +F+ K   F  HI  EHN+W+YLY+++ LR    +DYT  + +V  M K+ NLD++P  +A++L   +   E  +++   + L S +  + T      +L  +  +++ +++ +G
Sbjct: 2056 VYLFSIVGFLCLKEDFIMEVDPESNLERACDTLLMCIVTVLNHGLRNGGGVGDVLRKPSKDQEPLFPARV---VYDLLFYFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICLERD-KFDNKTVSFEEHINMEHNIWNYLYFIVLLREKNKTDYTGPESYVAHMMKNNNLDWFPRMQAMSLVVTDSDGEQNEMRILQDKLGSTMKVVTTLTAQLTELKEQMTEQRKRRQRMG 2291          

HSP 2 Score: 79.337 bits (194), Expect = 6.316e-14
Identity = 188/953 (19.73%), Postives = 372/953 (39.03%), Query Frame = 1
Query:  493 LRHVFSGYFIHINSNKLSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMASRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDXXXXXXXXXXXIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIR-SLTPSTNSNTYWVIEKANV-PYSMDPIAWNDMIRLKHGSTGFYLTLNY--------------KNKLFLSNNIHDPRTVLKFHPVNKDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKDEFSNEM---RSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCGFAPIIKSLKGKISNPTSMNDESLTR------YFTEAIGEISKNL--CIQNNPTKNRQKMMRTTKLIDWLFQIIELFGNLPVTAQMKWITPCQEIFSLINLYIGNNS--------------------KNTDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEK-VQLTHIKSILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLLQDGSAIGGIANTLYISTNAGKNWTQLSTFFDK--THYLYIESQCKFFLHQLDLLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELIITLFLNYGNHFMVMDYPIT-AYSYNNIGAPYSPSIRHKQEMHES-----------FPAIREWIGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDPILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDAKNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQLFQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYKYDSLLHKSLLFIAKFFSSQETVFTT 3165
            L H+ S  ++ +N    + ++K+A +  L     + +   I P +K+   G  V +G  V    + +      +N + +      E      N S   N F+++     D           +V  +H E E +LT + Y       K+H+ +R      +R S T +T+SN  W IE  +  P       WN + R KH +TG YL                  K KL + ++ +D  ++ +  P    + +       VR+ H+ +  W++ T +     +E    +         D  +F  V++   +  D  F  +  A             + +++ L     +P   ND    +      +F   +    +++   +   P + RQK+MR   ++  +F I++     P   +     P   +F L  L    NS                    +   ++AK F +    +     +  D IT L H   ++ ++ EK +  T +++ + +V  N+   FL +LS  C S +V I   Q+ I +  +++ K+   L++    +     T  I     K+  QL+    +  TH    +     + +QL L   +   R    I+ I+   K +   +   C+ +E +P D RA FC L++   ++     +V   P+  A  +  I  P S SI++   M +S              + E++ N +  N  + + N  +N L  +V  L  +LI +G++     L  L   +L ++D + +        +     +R         ++  + + +  ++D K+  LE+L+ +L  +L+ R   L+ +FK     V    D    T+       E     N+++  ++  ++     + +        +    VL+ LT ++Y  L+  +L  + + FS ++ V  T
Sbjct:   31 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVLVGDKVILNPVNAGQPLHASNYDLNDHSGCKEVNSVNCNTSWKINLFMMFSDHREDVLKGGD-----VVRLFHAEQEKFLTCDEY-----KSKLHVFLRTT----LRQSATSATSSNALWEIEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAEMDGRRISKRSQGERIKYKLVVLSDGNDIASLFELDPTTLQKTDSFVPNSYVRLRHLCTNTWIQSTNVPIDIDEERPIRLMLGTCPTKEDKEAFAIVSVPVMEIRDLDFANDASAM-----------LSTVVEQLTRGFISP---NDRFAIKLLEDVVFFVTDVANAGQSVLDVVMKKPNRERQKLMREQNILKQIFGILK----TPSAKREGGEAP---LFRLEELGDQKNSHYQYMFQLCYRVLRHSQEDYRKNQHIAKQFGMMQG-QIGYDILAEDTITALLH---NNRKLLEKHITKTEVETFVNLVRTNRE-PFLDYLSDLCVSNNVAIPVTQELICK-CVLDPKNQDILIKTVWLLW----TDKIKEKHEKSIRQLAQEARQGNTH----DENVLTYYYQLKLFARMCLDRQYLAIDEIS---KQLDVELIFLCMMDEMLPFDLRASFCRLMLHAHVDRDPQELVT--PVKFARLWTEI--PTSISIKYDSNMDDSRDNKKNRFANTMVFMEEYLNNVL--NDEMPFHNVEKNKLTYEVVSLARHLIYFGFY-SFFELLRLTRTLLGIIDSRPNPGHPGPIFQDDGPAQRG--------NKDSLEKMDLTVMDTKSKILEILQFILNVRLDYRLSFLLSVFKKEFVDVYPMADADATTNM------EQAATINLQRIGEQAEAMFGIKGNSILEVDDEGGRMFLRVLIHLTMHEYAPLVSGALQLLFRHFSQRQEVLHT 910          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Match: SMESG000060657.1 (SMESG000060657.1)

HSP 1 Score: 2934.44 bits (7606), Expect = 0.000e+0
Identity = 1527/1531 (99.74%), Postives = 1529/1531 (99.87%), Query Frame = 1
Query: 3625 MMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVXXXXXXXXXXXXXXXXXXXXXXAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNEDDERTENMNF 8217
            MMKKLSLIKVIFADREDLVVN SPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFI IAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNV+ESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNP+ESLNEDDERTENMNF
Sbjct:    1 MMKKLSLIKVIFADREDLVVNASPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFIWIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVIESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPQESLNEDDERTENMNF 1531          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Match: SMESG000060657.1 (SMESG000060657.1)

HSP 1 Score: 2932.51 bits (7601), Expect = 0.000e+0
Identity = 1526/1530 (99.74%), Postives = 1528/1530 (99.87%), Query Frame = 1
Query: 3628 MKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVXXXXXXXXXXXXXXXXXXXXXXAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNEDDERTENMNF 8217
            MKKLSLIKVIFADREDLVVN SPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFI IAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNV+ESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNP+ESLNEDDERTENMNF
Sbjct:    1 MKKLSLIKVIFADREDLVVNASPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFIWIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVIESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPQESLNEDDERTENMNF 1530          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Match: SMESG000060657.1 (SMESG000060657.1)

HSP 1 Score: 2928.66 bits (7591), Expect = 0.000e+0
Identity = 1527/1538 (99.28%), Postives = 1529/1538 (99.41%), Query Frame = 1
Query: 3604 MSLENQTMMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVXXXXXXXXXXXXXXXXXXXXXXAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNEDDERTENMNF 8217
            MSLENQTMMKKLSLIKVIFADREDLVVN SPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFI IAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDV       LFWNV+ESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNP+ESLNEDDERTENMNF
Sbjct:    1 MSLENQTMMKKLSLIKVIFADREDLVVNASPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFIWIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDV-------LFWNVIESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPQESLNEDDERTENMNF 1531          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Match: SMESG000060657.1 (SMESG000060657.1)

HSP 1 Score: 2913.25 bits (7551), Expect = 0.000e+0
Identity = 1520/1531 (99.28%), Postives = 1522/1531 (99.41%), Query Frame = 1
Query: 3625 MMKKLSLIKVIFADREDLVVNVSPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVXXXXXXXXXXXXXXXXXXXXXXAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNEDDERTENMNF 8217
            MMKKLSLIKVIFADREDLVVN SPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFI IAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDV       LFWNV+ESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNP+ESLNEDDERTENMNF
Sbjct:    1 MMKKLSLIKVIFADREDLVVNASPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFIWIAKLIMKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDV-------LFWNVIESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPQESLNEDDERTENMNF 1524          
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Match: SMESG000060657.1 (SMESG000060657.1)

HSP 1 Score: 2766.87 bits (7171), Expect = 0.000e+0
Identity = 1445/1447 (99.86%), Postives = 1447/1447 (100.00%), Query Frame = 1
Query: 3877 MSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAXXXXXXXXXXXXLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLXXXXXXXXXXXXQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPXXXXXXXXXXXXXXFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVXXXXXXXXXXXXXXXXXXXXXXAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCXXXXXXXXXXXXXXXVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNXXXXXXXXXXXXXXMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNEDDERTENMNF 8217
            MSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNV+ESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNP+ESLNEDDERTENMNF
Sbjct:    1 MSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLEFVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTNYIVTDVTLLLKGRLFWNVIESIKETNVKWLDKLKQMSPQYQYDVLLAIRDAENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLIIQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVRSDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKYPGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFAKLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEIKRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPVTVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDMKKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIKKSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNPKSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLVNGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHELAKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILISLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIPSIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDLIEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYLWNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKIHMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDSAKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHANENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITGSDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIIIYAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQFDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSKYDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKISDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLMSIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNKNPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPQESLNEDDERTENMNF 1447          
The following BLAST results are available for this feature:
BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ITPR12.073e-2821.60inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.484e-2821.60inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.647e-2822.04inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.760e-2822.04inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
ITPR12.760e-2822.04inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itr-11.569e-1424.46Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-11.767e-1424.46Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-11.780e-1424.46Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-11.990e-1424.46Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
itr-12.054e-1424.46Inositol 1,4,5-trisphosphate receptor itr-1 [Sour... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
RyR6.339e-1428.57gene:FBgn0011286 transcript:FBtr0304568[more]
RyR6.446e-1428.57gene:FBgn0011286 transcript:FBtr0088638[more]
RyR6.447e-1428.57gene:FBgn0011286 transcript:FBtr0088637[more]
RyR6.502e-1428.57gene:FBgn0011286 transcript:FBtr0304572[more]
RyR6.610e-1428.57gene:FBgn0011286 transcript:FBtr0088639[more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr1a2.019e-2721.79inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
itpr1a3.823e-2721.79inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
itpr1a6.541e-2621.48inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
itpr1a8.386e-2621.48inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
itpr1a9.609e-2621.48inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
rasgrp11.522e-2721.42RAS guanyl releasing protein 1 [Source:Xenbase;Acc... [more]
rasgrp12.574e-2621.27RAS guanyl releasing protein 1 [Source:Xenbase;Acc... [more]
rasgrp13.967e-2621.27RAS guanyl releasing protein 1 [Source:Xenbase;Acc... [more]
sfi19.104e-2621.55SFI1 centrin binding protein [Source:Xenbase;Acc:X... [more]
c1qbp3.433e-2421.20complement component 1, q subcomponent binding pro... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Itpr33.220e-2821.60inositol 1,4,5-triphosphate receptor 3 [Source:MGI... [more]
Itpr22.278e-2521.47inositol 1,4,5-triphosphate receptor 2 [Source:MGI... [more]
Ryr12.379e-1729.33ryanodine receptor 1, skeletal muscle [Source:MGI ... [more]
Ryr12.543e-1729.33ryanodine receptor 1, skeletal muscle [Source:MGI ... [more]
Ryr12.742e-1729.33ryanodine receptor 1, skeletal muscle [Source:MGI ... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P70227|ITPR3_MOUSE2.252e-2721.60Inositol 1,4,5-trisphosphate receptor type 3 OS=Mu... [more]
sp|Q63269|ITPR3_RAT3.570e-2621.42Inositol 1,4,5-trisphosphate receptor type 3 OS=Ra... [more]
sp|Q8WN95|ITPR3_BOVIN6.754e-2620.97Inositol 1,4,5-trisphosphate receptor type 3 OS=Bo... [more]
sp|Q14643|ITPR1_HUMAN7.226e-2621.69Inositol 1,4,5-trisphosphate receptor type 1 OS=Ho... [more]
sp|Q14573|ITPR3_HUMAN3.361e-2521.08Inositol 1,4,5-trisphosphate receptor type 3 OS=Ho... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S3H6U35.224e-3526.87inositol 1,4,5-trisphosphate receptor type 1 isofo... [more]
A0A1S3H6U85.585e-3526.89inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
A0A1S3H6V55.743e-3526.73inositol 1,4,5-trisphosphate receptor type 3 isofo... [more]
A0A210PSZ21.232e-6128.18Inositol 1,4,5-trisphosphate receptor type 1 OS=Mi... [more]
A0A267G7Y31.838e-6226.17Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr21.660e-2422.16inositol 1,4,5-trisphosphate receptor, type 2 [Sou... [more]
ryr1b2.758e-1829.78ryanodine receptor 1b (skeletal) [Source:ZFIN;Acc:... [more]
ryr1a7.862e-1829.78ryanodine receptor 1a (skeletal) [Source:ZFIN;Acc:... [more]
ryr32.006e-1628.89ryanodine receptor 3 [Source:ZFIN;Acc:ZDB-GENE-041... [more]
itpr1a1.498e-1528.20inositol 1,4,5-trisphosphate receptor, type 1a [So... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000007822.11.595e-1234.02pep scaffold:Pmarinus_7.0:GL476823:160879:181935:-... [more]
ENSPMAT00000007816.12.517e-1234.38pep scaffold:Pmarinus_7.0:GL476823:160879:205429:-... [more]
ENSPMAT00000003582.14.907e-1123.57pep scaffold:Pmarinus_7.0:GL477251:10655:41631:-1 ... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO378769.299e-3320.70Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO285922.509e-1829.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
itpr1b7.850e-2920.97inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
itpr1a6.965e-2520.36inositol 1,4,5-trisphosphate receptor type 1 [Sour... [more]
itpr21.280e-1425.17inositol 1,4,5-trisphosphate receptor, type 2 [Sou... [more]
ryr1b2.686e-1427.11ryanodine receptor 1 [Source:NCBI gene;Acc:1011600... [more]
itpr35.251e-1429.58inositol 1,4,5-trisphosphate receptor type 3 [Sour... [more]
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BLAST of inositol 1,4,5-trisphosphate receptor type 3 isoform X13 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000060657.10.000e+099.74SMESG000060657.1[more]
SMESG000060657.10.000e+099.74SMESG000060657.1[more]
SMESG000060657.10.000e+099.28SMESG000060657.1[more]
SMESG000060657.10.000e+099.28SMESG000060657.1[more]
SMESG000060657.10.000e+099.86SMESG000060657.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024629 ID=SMED30024629|Name=inositol 1,4,5-trisphosphate receptor type 3 isoform X13|organism=Schmidtea mediterranea sexual|type=transcript|length=8317bp
ATTATACACTAGATCAGACCACTTATACAGATTCAATTCTATTTTTATTA
TAAATTATTTTACAATTTCTTTTCGGATTTCCGATATCTAATGGCGAATT
CTGATGAGGTCGTGACGAACGATTTTTCGCAGTTCTTGTCATTTGGCGAT
TATATCGCACTGTATAGTGAGCAGGATTTAGGATATTTAGCGGCGGACTC
ATCTAGTCAAATTCTCAACGAGCCATTCGTATACAGCCGACAGAGTTATG
ATCTTCCAGAGAATGTTCCAACTATGTCAATGCTGTTGTTTGAAGTCTGT
GTATGTCATCGTTATAAAATGGACAAAAGGTACAGAAAACTAAAAGAAGC
AGACGATGGAAGCCCAAATTCGGCCGATCGACTAGATAAACTTAAAAAAT
TAAAAGATGCGGCAGCGTTAGAAGATAAAGATAACATGCAAGTCATGAAA
AGAAATATTGGGAGGAAATTACGTTTTGGAGACATCATTCAATTGCGTCA
TGTATTCAGTGGATATTTCATACATATTAATTCCAACAAGTTGAGCAAAA
TTCAAAAAAGCGCTTTCAAAACGGTGTTACTACCATACAGTGCAAAATCA
GCTCAATTTCAAATTGTTCCCAAATACAAAGTGGACGTTGAAGGAGCTGA
AGTGAATATCGGGGCGTATGTTTCATTTGAAAGCATGGCAAGTAGAAGTT
ACTACTTTCATACCAATCCGAATCCTTCTTATCCCCGATCAGAAACCGAA
CCCGGAATCTCTGAATTCAACGTGAGCCTTGACAAAAACGGATTCATTGT
TTACAAATCAAGAAGCCGTGACAAAAATTTGAAAAATTTATTAAATGGGC
TGAATATTGTTCATTTTTACCACCAAGAGACGGAAGCGTATTTAACTGCC
GAAGGCTATTTTAGAGGAGAGATCAGTGAAAAAATACATATGAGGATAAG
AAAGATTGACTTATTAGACATTCGGTCATTGACCCCGTCAACTAATTCCA
ATACTTATTGGGTCATCGAAAAGGCGAACGTTCCCTACTCAATGGATCCA
ATTGCATGGAATGACATGATTCGGCTGAAACACGGTTCGACAGGGTTTTA
TTTGACCCTCAACTATAAAAATAAGTTGTTTTTGTCAAATAATATTCACG
ATCCAAGGACTGTGTTGAAATTTCATCCAGTCAACAAGGATCGAGATGAA
TTTATTCGAAAAGGAATAAATGTTCGGGTTGAACACGTTATTTCCGGTCG
GTGGTTAAAAGTAACCCCATTAATCACGTACACAAAAGATGAATTTTCTA
ACGAAATGAGGTCACAGGTTATATGGGACAACGCTTCATTTATTACGGTA
ACAATGGATGATGACCAACGGTATGATGACGCTTTCAACATAGAGGATGT
TGCAAAACCGGAAAAGCAAATCTTTCACAAGTTTTGTGGATTTGCTCCAA
TTATTAAAAGTTTAAAAGGAAAAATATCGAACCCCACCTCAATGAACGAT
GAGAGTTTGACTCGCTACTTTACCGAGGCCATTGGGGAAATTTCTAAAAA
TCTTTGCATTCAAAATAATCCAACTAAAAACAGACAGAAAATGATGAGGA
CTACAAAATTGATTGATTGGCTTTTTCAAATCATTGAACTTTTCGGTAAT
TTGCCGGTCACTGCTCAGATGAAATGGATTACTCCGTGCCAGGAGATATT
TTCCCTCATCAACCTTTACATTGGAAACAACAGCAAAAATACAGATTATG
TTGCCAAGTATTTCCAAATATTCACAGATCCAAAATGGAACAACAGTCCG
ATCATCAGTGACGTAATCACAATGTTAACCCATATGATATCTAGTAGTCC
AAGAGTCGCAGAAAAAGTCCAGTTGACTCACATTAAATCTATTCTACAAA
TGGTCCATGGAAATCAGAATTATGTATTTCTGAAATTTCTCTCACAGACA
TGTTCAAGCAAAGACGTCCCAATTATTAGCAATCAGGATTTCATTGCTCA
GGAATGGCTAGTCAATGATAAAAGTGGACTTTATTTATTGCAAGATGGAA
GCGCCATCGGAGGAATAGCAAATACTCTTTATATCAGTACTAATGCCGGT
AAAAACTGGACTCAGTTAAGTACATTCTTTGATAAAACTCATTATCTGTA
CATTGAATCCCAGTGCAAATTCTTTCTCCACCAACTGGACCTTTTAAAAG
CCATAACCACCGGTAGAAACATGAAGGTTATCGAAATGATTACTACCAAG
GAGAAATATATTACATGGTCTATGGCAATATCTTGTATTCAAAATGAGGA
AATGCCAGACGACTTCCGGGCAAAATTTTGTGAATTGATAATAACCTTAT
TTTTAAACTATGGGAACCATTTCATGGTAATGGATTATCCAATTACGGCT
TATTCTTACAATAACATTGGAGCACCATACAGTCCAAGTATTAGACATAA
GCAAGAAATGCACGAATCATTTCCAGCAATAAGGGAGTGGATTGGAAACT
TTATCTTTCAAAATTCAAGTCTTATATATGAAAATACCGGACGGAATCAT
CTCATTATTCAAGTTTTCTATTTATTGTTGAATCTGATCAAATACGGCTA
TTTTGACGACACCAGTTCTTTGCATGAGTTAATTGATCCAATACTCAATG
TACTCGATGGGAAAAATGATAAAAAATTTAGATCGTCCTTCAATAAAGGT
TTTACGATGATGGAAAGAGATGAATTACAAGATTTTCATTATCGCAGTCG
ATTTGAAGTTTCGGAATGCAATAATGTCATTGTTGATGCAAAAAATGCAG
GTTTAGAAGTCCTGGAAATGCTACTTATGTTTCAATTGAACAAGAGAACG
GAGGGTTTAGTCCACCTATTCAAAGATACCAGAGCAGCAGTAATGGTCAA
CCAAGACCAACGAAAACAGACTGATTTCATGGCTCAATTATTCCAAGAAA
ATTTTGATATAAACAATATCAAGAAAGCTTCTAAAGAGTGTCGATCAATT
GAAACCTCTTTAAAATCACTAATGAGCTCTACTCAATACTTTGACATCCA
ACGGATACGAGAAGTTCTACTTGATCTCACTCATTACAAATATGATTCAT
TATTGCACAAAAGTTTGCTTTTTATAGCAAAATTTTTCAGTAGTCAAGAA
ACAGTTTTTACAACTGCTACTGATATGATGATAACACATGGAAAGGATTC
AGATTCGTGGTTAAAAATGATTCAAGATTTCGCCCCTCAATTGGACATAC
TGATCACGGGAGATTGGAATCATTCCGCATTATCAAACTATCGCAGTATT
CTCGCATCCATCCGAGCTTATTGCACCCTGCCCAGTTGTAACATTCCAAA
TGTCGTGTTTCAGAAAATTCTTTACAGTTGCAATATTGTTGATATTTTAT
TCAAAGTTTTCGAGAAAGAATGCGGCTCAAAAAGCGGATTTTCATCGAAA
AAAGCTCATATTTACAGAAAGATATCAAAGATTCGTCCGGAAAATCACGG
AAAGATATATCTGATGTATGGAGAAACAATGGACTGCCTAAAAGTGATGG
CCAAGGAAATGGTTGGTGTACAGAACATTTTATTCAGTAGACTCGAATTG
ATAATGTCTCTGGAAAATCAAACTATGATGAAGAAACTCTCCTTGATAAA
GGTGATCTTTGCTGATCGGGAGGATCTTGTGGTCAATGTCTCCCCAAGTG
TCATTGAATGGCTTTTCAAATGGATCCGATTGCACAAAGAAGACGCACCA
GATATTTTGAATTTGATTTTGTGCCTAGGTCAAGTTCAATATACACAGAA
ATTGATCCGAAACAATTTTATTTGCATAGCAAAATTGATCATGAAATATT
GGTTGGATTTTGGTTCGTTCTGTGAAATGAGTTTTGAAGAAAAATTGGAC
TTATTTTCCAAGGTTGATGACAGTCCAGAGAAAATGTTTTTCCTCCGATT
GCTCTATTTGATTGGGGTTGCCGGAGAGATGGGATTAGAATTTGTGGAAT
CATTCGGACAAACAGTTTTGAGTCTCGACAACTGTCTAAATCTTTTTTCA
GAAATTCCTGATCTTCTCGTCCAAAGATCAATTCTGAAATTCGTCTCGGA
AATTTATATAAAATCCGAAAGCAATTTCAAACATACAAATTATATAGTGA
CAGATGTGACATTATTATTAAAGGGACGTCTCTTTTGGAACGTCGTAGAA
TCCATCAAGGAAACAAATGTCAAATGGCTTGATAAATTAAAACAAATGTC
ACCACAATATCAATACGATGTTTTGCTAGCGATTCGTGATGCAGAGAATC
TCGGTGATCCAGATTACTTATACATGTCATGGCTGATGGATGGGGTCATA
CCATTTATGACAGAAACCTTGAGAGCCCAAACTACTTCACCGGTAACAGT
TACGCAACAACAGTTGATGATTAAAAATGTTAAACTTATAATTCAAATTT
TGACAATTCTGTCATCAAATTTTTCGATTTTACACCAAATAGAAATAGCG
ACTGGTTACTTATTTGCAGCGGTCTTGTCAAACTATGAACGATACATCAG
CCTTGAACCGGTTATTGTCAAACTGAGTAGCAATGTTCGCAGTGACAGCG
TAAATTCCAGACAAACCTTTAAAGAATTTCTCCAAACCCACAAAGAGGAA
ATCGACCTGAATAGGGAATTTAAAAACTTTTTGAAAAACACTCATTCGCT
TTTAGTTGGTAAAAATAGTGCAGATAGCCAAATAAAATATCCGGGACATC
CAAGCGGAATTCGCCGGCTCAGTAACCAAGAATATACGTCTGTGAATACA
GTTGAAGCACTTCCATTAGGAGAGGAATTTCAGTCTCTGGTGCAAACATT
TCTCAATATGGACGAAATAGAACCGAAAAAAAGATTTGCCAAATTAATAA
ATATAATCCGACACTTAAAAATGCCACTGCCGAGAATGGCGGCCAAGGCC
GGATTCGTTACTCAGAAAATTGTCAAGGATCAAGATTCGTTGAATATAAT
TTGTTTCAGAATTTTGCGTGCAGTACTGCAAAATGAAATTAAACGTCTTC
CCGAAGACTGGCCTGAATATATAAACAATCCCGCTATTGACGGACAGCTG
CAGTACATCCGCAACATTCAGTCAGCGTTTTGCGATTTCAATTTGTTCGA
ATCCGTTTTGCATCATGCGTCAAGAGTAAAATCTCCAGTAACAGTCGAGC
TGTTTGCCTTTCTCAAAGTGTTATTTTTCAACGCGTCAACTTACGTGCAA
GAATATATTTATAATTTCTTTATCGTTTCCGTCACAGAAACCTTTTTCTT
TGCCATTAAAGAATTTCTAGCCATTTTCGAAGAAGATATGAAAAAATTGC
GGCGAAACCTTAACGCAAAGGTAAAGGAAAGAATAAAAGAGGAAACCCAA
TTTCGAGTTCGCCGACAAACATTGACAAATATGAATTTAACCGTATACTA
CGAATGTAAAGATTATTTTGCAGAAATCGATAAAATTAAAAAGAGCGTGC
TGGATAACGTGACCCCATTGAAATTTCAATCTATTATTGAAAATGGGTTC
GGTATTTTATTAATGCAAGTTCTGCAAAGTCTGTGTGAAGGTCAATTTTT
AAAATTGCAGGACTACATGAGAGTTCAGGAAGACAACCCGAAATCATTTA
ATTTGGTGTTTAGAACATGTACAGTGGTGAACACGATTTATGCCAACATT
AATTCTAATACTATCGGAATCCTGACCCAAATCCTTGGAGCACTTAATCA
AATGGCTATAGGCAACCAGGAGAATCGGATCACTCTCGTCAACGGAAAAA
TAATTGATTACATCAATTTCATTTTACGAACGAATGAGTTTAACGGAGCG
AAACCTGATCAAGTGTTAGACCTGCGTGACATGGTGGCAAATCTTATAAT
CACACTGGTAGAAGAGGACGCCACAGCAGCGCACGAACTAGCGAAGGAAA
TAATGATAACTGTTGATAAGAAAGCAATTTTCAATATTATTCTTCAATAT
TACCAATTTTCAAAGAAAGATGCACTTCCTAACTTGGAGGAGTTAACAAC
ATTTTCAAAGAAACCGGAAGAGAAAACAGGAATATTAATTTCACTGAAGC
GTGCTATTTTGAATTTACCAACTCTGAAAGCTACACAATTGAAAAAGATG
TCCGCAATCAAAGAAAGAATTTATGACATCGGATATAAATACTCTTCAAT
TTTAATGAGATTCGAAGACATTGACCCTAAACTTATTCCGTCAATTGCCG
AAGATGATGTAACTATTCAGCACAAGGCTGCCTATAAAGGTTTAAAGAAA
GGAGGAACGTCCATAGAGATTATCAAAGATGATTGTGTTCAACGAGTGCA
TTTCCGAATCAAAAATAGAAAAGTGATTAGAGAAGATCTAATTGAAAAGA
TCAAATGGGATGTAGATAGAACGTCAAGTGCGTCAAAGGTCCGAGATTTT
ACACTATGGGCAGATTCTGTGATAATGGATTTAGAAAAGTCGAAGAAAGC
GAATCCGGTAAAAATCTTCATGATCCAATCATGGTATTTGTGGAATTATT
TACCGATTCTGCTAAGTTTGGTGTTGAATATAATGATGCTATTATCGTTC
AAGAGTAAAGGATCCCTAATTGATGAGACTTTCTCGACTAATCTAACAAA
CCCATATCCCGATTTTGCTCACTATCCAGTCTTAAAAATTCATATGATTT
ATATATCAACACTTCACACAATATTTTCACTCTGTCTTCTCATAACCTAT
GTGCTCATTTCCAAACCCGGATTCAACAACATCCGTCAGTTGAAATCCTA
CGTGGAAAGGTTATGCCAACAGTTGCCAGTAACGGATTCTGCCAAATCAA
ATAAGAACATTAAATTACTAAAAGAAGCTGAAAAACGAATTGATATGCTT
CATGAAAGTGAACAAGCGGATGCAATAATTGAATTAAAGAATTTAATGAG
GAAAATTGAACAGAAATCCAACAACTTGGCTCATGCTAATGAAAACGAGG
ATAATGTTAATGCATGTAATCATGGGAAGAATAAACTTAACGCGAATGTT
TTGAGTTTAAAATCCACGTATTATTTCTTGTTCTTTTTGTCGTCATTACT
TGGAACAATATTCGGTGCATACGCCACCCAGATAACCGGATCTGACAAAT
ACTTGGTGGCATATTACCTTTTCGCGTTTCATTTAATGAATATTGCGCTT
GTTGTCACGGATTTAACAGGAGTTTTCCAAGCAGTTAGGCAGAGTCTTCC
TTCAATGGCATGGGTCGGCCTGTTGATATTAATCATCATTTATGCATTCA
CTTTGGTTATATTTGTACTGTTCCGTGATGCAATGAACATGTCCTCAAAT
CTTTACTGTGATACACTCGGCCATTGTTATACGACTTTGATACGTTTTGG
ATTCATTTTTGATAAATGGATGGAGTTATTCGTTCCTCAATTCGATTCGA
AAAAGAACTTTGTAAGTGTGGTCTACATGAGCATTTTCACAGTGATGCTG
TGCATAATCGTGGCCATTATAATGCTCAACATCATAGCTGGTATCATCGT
GGACAAGTTTGCAACCGCTCGTAATCTGAAGGACTCAAAATATGATGACA
TGATCAACTATTGTTTCATTTGTAGCAGAAGTAGTTATGAATTCGAGACA
AAGGCTAAGGGATTTAGATATCACATTCTAAAAGAGCATAACATGTGGTC
ATATCTCTATTATATGATCTCATTGAGATCTATGAAGATAAGTGACTACA
CAGCCCTCCAGTGGCATGTACATAAAATGTATAAATCAAAAAACCTAGAT
TTCTATCCCATTGATAGAGCTCTAGCCCTAACTAGGAATGAAGAACTAAC
GGAGGATGAAAAGCTGAAAGAAACAAGTGAAATGCTAATGTCAATAATTG
ACGAAATTGACACTAATAAATTACATCGTGAACAGCTGAATAGAAAACAG
AGACAAGAGAAATGGAAGAAAGAAGCTCTGGGTGAAGGTGAAAATACCTT
GAAAGTAGAAACTACAGAAAGAATTAACTTGTATAATAAAAACCCTTCCA
TATCAATTGACTACCGCCAAATGGATCCAGCATTTGAAGATTTGTTTATC
GAAGAAGACCTATTTTGCCCAAGTACGAATATCAATTCCATACCGATAAA
TATGATAACATTCAATCCTCGAGAATCTCTCAACGAAGATGATGAAAGAA
CCGAAAATATGAATTTCTAATATCTCACAATTTATGATTTAATCTCTTTT
TGTCTTTTAATTATATTTCTTAAAACAATTTGAATGGACTTTAAACTGAG
AAGTTGTAACTTTGGTG
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protein sequence of SMED30024629-orf-1

>SMED30024629-orf-1 ID=SMED30024629-orf-1|Name=SMED30024629-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=2710bp
MANSDEVVTNDFSQFLSFGDYIALYSEQDLGYLAADSSSQILNEPFVYSR
QSYDLPENVPTMSMLLFEVCVCHRYKMDKRYRKLKEADDGSPNSADRLDK
LKKLKDAAALEDKDNMQVMKRNIGRKLRFGDIIQLRHVFSGYFIHINSNK
LSKIQKSAFKTVLLPYSAKSAQFQIVPKYKVDVEGAEVNIGAYVSFESMA
SRSYYFHTNPNPSYPRSETEPGISEFNVSLDKNGFIVYKSRSRDKNLKNL
LNGLNIVHFYHQETEAYLTAEGYFRGEISEKIHMRIRKIDLLDIRSLTPS
TNSNTYWVIEKANVPYSMDPIAWNDMIRLKHGSTGFYLTLNYKNKLFLSN
NIHDPRTVLKFHPVNKDRDEFIRKGINVRVEHVISGRWLKVTPLITYTKD
EFSNEMRSQVIWDNASFITVTMDDDQRYDDAFNIEDVAKPEKQIFHKFCG
FAPIIKSLKGKISNPTSMNDESLTRYFTEAIGEISKNLCIQNNPTKNRQK
MMRTTKLIDWLFQIIELFGNLPVTAQMKWITPCQEIFSLINLYIGNNSKN
TDYVAKYFQIFTDPKWNNSPIISDVITMLTHMISSSPRVAEKVQLTHIKS
ILQMVHGNQNYVFLKFLSQTCSSKDVPIISNQDFIAQEWLVNDKSGLYLL
QDGSAIGGIANTLYISTNAGKNWTQLSTFFDKTHYLYIESQCKFFLHQLD
LLKAITTGRNMKVIEMITTKEKYITWSMAISCIQNEEMPDDFRAKFCELI
ITLFLNYGNHFMVMDYPITAYSYNNIGAPYSPSIRHKQEMHESFPAIREW
IGNFIFQNSSLIYENTGRNHLIIQVFYLLLNLIKYGYFDDTSSLHELIDP
ILNVLDGKNDKKFRSSFNKGFTMMERDELQDFHYRSRFEVSECNNVIVDA
KNAGLEVLEMLLMFQLNKRTEGLVHLFKDTRAAVMVNQDQRKQTDFMAQL
FQENFDINNIKKASKECRSIETSLKSLMSSTQYFDIQRIREVLLDLTHYK
YDSLLHKSLLFIAKFFSSQETVFTTATDMMITHGKDSDSWLKMIQDFAPQ
LDILITGDWNHSALSNYRSILASIRAYCTLPSCNIPNVVFQKILYSCNIV
DILFKVFEKECGSKSGFSSKKAHIYRKISKIRPENHGKIYLMYGETMDCL
KVMAKEMVGVQNILFSRLELIMSLENQTMMKKLSLIKVIFADREDLVVNV
SPSVIEWLFKWIRLHKEDAPDILNLILCLGQVQYTQKLIRNNFICIAKLI
MKYWLDFGSFCEMSFEEKLDLFSKVDDSPEKMFFLRLLYLIGVAGEMGLE
FVESFGQTVLSLDNCLNLFSEIPDLLVQRSILKFVSEIYIKSESNFKHTN
YIVTDVTLLLKGRLFWNVVESIKETNVKWLDKLKQMSPQYQYDVLLAIRD
AENLGDPDYLYMSWLMDGVIPFMTETLRAQTTSPVTVTQQQLMIKNVKLI
IQILTILSSNFSILHQIEIATGYLFAAVLSNYERYISLEPVIVKLSSNVR
SDSVNSRQTFKEFLQTHKEEIDLNREFKNFLKNTHSLLVGKNSADSQIKY
PGHPSGIRRLSNQEYTSVNTVEALPLGEEFQSLVQTFLNMDEIEPKKRFA
KLINIIRHLKMPLPRMAAKAGFVTQKIVKDQDSLNIICFRILRAVLQNEI
KRLPEDWPEYINNPAIDGQLQYIRNIQSAFCDFNLFESVLHHASRVKSPV
TVELFAFLKVLFFNASTYVQEYIYNFFIVSVTETFFFAIKEFLAIFEEDM
KKLRRNLNAKVKERIKEETQFRVRRQTLTNMNLTVYYECKDYFAEIDKIK
KSVLDNVTPLKFQSIIENGFGILLMQVLQSLCEGQFLKLQDYMRVQEDNP
KSFNLVFRTCTVVNTIYANINSNTIGILTQILGALNQMAIGNQENRITLV
NGKIIDYINFILRTNEFNGAKPDQVLDLRDMVANLIITLVEEDATAAHEL
AKEIMITVDKKAIFNIILQYYQFSKKDALPNLEELTTFSKKPEEKTGILI
SLKRAILNLPTLKATQLKKMSAIKERIYDIGYKYSSILMRFEDIDPKLIP
SIAEDDVTIQHKAAYKGLKKGGTSIEIIKDDCVQRVHFRIKNRKVIREDL
IEKIKWDVDRTSSASKVRDFTLWADSVIMDLEKSKKANPVKIFMIQSWYL
WNYLPILLSLVLNIMMLLSFKSKGSLIDETFSTNLTNPYPDFAHYPVLKI
HMIYISTLHTIFSLCLLITYVLISKPGFNNIRQLKSYVERLCQQLPVTDS
AKSNKNIKLLKEAEKRIDMLHESEQADAIIELKNLMRKIEQKSNNLAHAN
ENEDNVNACNHGKNKLNANVLSLKSTYYFLFFLSSLLGTIFGAYATQITG
SDKYLVAYYLFAFHLMNIALVVTDLTGVFQAVRQSLPSMAWVGLLILIII
YAFTLVIFVLFRDAMNMSSNLYCDTLGHCYTTLIRFGFIFDKWMELFVPQ
FDSKKNFVSVVYMSIFTVMLCIIVAIIMLNIIAGIIVDKFATARNLKDSK
YDDMINYCFICSRSSYEFETKAKGFRYHILKEHNMWSYLYYMISLRSMKI
SDYTALQWHVHKMYKSKNLDFYPIDRALALTRNEELTEDEKLKETSEMLM
SIIDEIDTNKLHREQLNRKQRQEKWKKEALGEGENTLKVETTERINLYNK
NPSISIDYRQMDPAFEDLFIEEDLFCPSTNINSIPINMITFNPRESLNED
DERTENMNF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0070679inositol 1,4,5 trisphosphate binding
GO:0005220inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262calcium channel activity
GO:0005216ion channel activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000016pharynx
PLANA:0000020protonephridia
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR000493InsP3_rcpt
IPR016093MIR_motif
IPR000699RIH_dom
IPR014821Ins145_P3_rcpt
IPR005821Ion_trans_dom
IPR013662RIH_assoc-dom
Vocabulary: cellular component
TermDefinition
GO:0005783endoplasmic reticulum
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: biological process
TermDefinition
GO:0006816calcium ion transport
GO:0070588calcium ion transmembrane transport
GO:0055085transmembrane transport
GO:0006811ion transport
GO:0048016inositol phosphate-mediated signaling
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1150..1177
NoneNo IPR availableCOILSCoilCoilcoord: 602..629
NoneNo IPR availableGENE3DG3DSA:1.10.287.70coord: 1248..1370
e-value: 5.0E-8
score: 34.8
NoneNo IPR availablePANTHERPTHR13715RYANODINE RECEPTOR AND IP3 RECEPTORcoord: 1195..1497
NoneNo IPR availablePANTHERPTHR13715RYANODINE RECEPTOR AND IP3 RECEPTORcoord: 5..1062
NoneNo IPR availablePANTHERPTHR13715:SF99INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-LIKE PROTEIN Acoord: 1195..1497
NoneNo IPR availablePANTHERPTHR13715:SF99INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-LIKE PROTEIN Acoord: 5..1062
NoneNo IPR availableTMHMMTMhelixcoord: 1340..1362
NoneNo IPR availableTMHMMTMhelixcoord: 1264..1286
NoneNo IPR availableTMHMMTMhelixcoord: 1023..1045
NoneNo IPR availableTMHMMTMhelixcoord: 581..603
NoneNo IPR availableTMHMMTMhelixcoord: 1077..1099
NoneNo IPR availableTMHMMTMhelixcoord: 1235..1257
NoneNo IPR availableTMHMMTMhelixcoord: 1203..1225
IPR013662RyR/IP3R Homology associated domainPFAMPF08454RIH_assoccoord: 683..771
e-value: 1.3E-15
score: 57.1
IPR005821Ion transport domainPFAMPF00520Ion_transcoord: 1202..1369
e-value: 8.7E-8
score: 31.7