Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2

Overview
NameRetrovirus-related Pol polyprotein from type-1 retrotransposable element R2
Smed IDSMED30024599
Length (bp)531
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30024599

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30024599 dd_Smed_v4_28437_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30024599 dd_Smed_v4_28437_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30024599 dd_Smed_v4_28437_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Match: BX284696.1 (pep chromosome:GRCz11:7:42935126:42939263:1 gene:ENSDARG00000099710.2 transcript:ENSDART00000157747.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX284696.1)

HSP 1 Score: 86.6557 bits (213), Expect = 8.211e-20
Identity = 49/176 (27.84%), Postives = 94/176 (53.41%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHN-SVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  L+N+ I +K +   +K     +IPKP+KD    L+ +WRPI LL+V YK+ A + + RL + +   NL+    + G ++   + +N  ++   ++++ +  N+   I +LD   AF ++ H ++   L++ G    F N++ + Y D SS        +    +++GV+QGC
Sbjct:  495 ILLILYNECIAEKEMSTTMKQGIISLIPKPEKDS--LLIDNWRPITLLTVDYKILALVFSNRLKTKL---NLMITESQSGFLNGRHISNNIRLVLDLIDYADFI-NSKAIIFFLDFYKAFDTIEHKFLLHSLKKFGFGSTFINVIEMFYKDISSSIIINMFTSQRFTLERGVRQGC 664
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Match: BX511246.1 (pep chromosome:GRCz11:23:9353552:9357627:1 gene:ENSDARG00000100234.2 transcript:ENSDART00000163298.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX511246.1)

HSP 1 Score: 86.6557 bits (213), Expect = 8.534e-20
Identity = 49/176 (27.84%), Postives = 94/176 (53.41%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHN-SVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  L+N+ I +K +   +K     +IPKP+KD    L+ +WRPI LL+V YK+ A + + RL + +   NL+    + G ++   + +N  ++   ++++ +  N+   I +LD   AF ++ H ++   L++ G    F N++ + Y D SS        +    +++GV+QGC
Sbjct:  495 ILLMLYNECIAEKEMSTTMKQGIISLIPKPEKDS--LLIDNWRPITLLTVDYKILALVFSNRLKTKL---NLIITESQSGFLNGRHISNNIRLVLDLIDYADFI-NSKAIIFFLDFYKAFDTIEHKFLLHSLKKFGFGSTFINVIEMFYKDISSSIIINMFTSQRFTLERGVRQGC 664
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Match: si:dkeyp-88h4.2 (si:dkeyp-88h4.2 [Source:ZFIN;Acc:ZDB-GENE-131121-105])

HSP 1 Score: 82.4185 bits (202), Expect = 2.422e-18
Identity = 54/167 (32.34%), Postives = 88/167 (52.69%), Query Frame = 2 
Query:   38 DKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHV---GQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++T+   +K     +IPKPDKD   T++ +WRPI LL+  YK+ ASI A+RL    KR+  LH      + G I    +  N+ L   L   K   ++   I +LD   AF +V H+++   L+  G   +F N++++LY D +S        +P   + +G++QGC
Sbjct:   41 NETMTPTMKQGVISLIPKPDKDP--TIIDNWRPITLLNFDYKLLASIFAKRL----KRH--LHYIINETQTGFIKGRHISCNTRLVLDLIDYKNEIDSDAIILFLDFYKAFDTVKHEFLLDSLKAFGFPLKFLNVVQMLYKDINSCVILNSCTSPRFPVLRGIRQGC 199
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Match: CU024870.2 (pep chromosome:GRCz11:25:23489979:23495448:1 gene:ENSDARG00000103841.2 transcript:ENSDART00000158200.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CU024870.2)

HSP 1 Score: 82.0333 bits (201), Expect = 3.240e-18
Identity = 54/167 (32.34%), Postives = 88/167 (52.69%), Query Frame = 2 
Query:   38 DKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHV---GQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++T+   +K     +IPKPDKD   T++ +WRPI LL+  YK+ ASI A+RL    KR+  LH      + G I    +  N+ L   L   K   ++   I +LD   AF +V H+++   L+  G   +F N++++LY D +S        +P   + +G++QGC
Sbjct:  506 NETMTPTMKQGVISLIPKPDKDP--TIIDNWRPITLLNFDYKLLASIFAKRL----KRH--LHYIINETQTGFIKGRHISCNTRLVLDLIDYKNEIDSDAIILFLDFYKAFDTVKHEFLLDSLKAFGFPLKFLNVVQMLYKDINSCVILNSCTSPRFPVLRGIRQGC 664
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Match: BX544877.2 (pep chromosome:GRCz11:25:25310063:25315481:1 gene:ENSDARG00000103976.2 transcript:ENSDART00000164291.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX544877.2)

HSP 1 Score: 82.0333 bits (201), Expect = 3.468e-18
Identity = 54/167 (32.34%), Postives = 88/167 (52.69%), Query Frame = 2 
Query:   38 DKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHV---GQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++T+   +K     +IPKPDKD   T++ +WRPI LL+  YK+ ASI A+RL    KR+  LH      + G I    +  N+ L   L   K   ++   I +LD   AF +V H+++   L+  G   +F N++++LY D +S        +P   + +G++QGC
Sbjct:  506 NETMTPTMKQGVISLIPKPDKDP--TIIDNWRPITLLNFDYKLLASIFAKRL----KRH--LHYIINETQTGFIKGRHISCNTRLVLDLIDYKNEIDSDAIILFLDFYKAFDTVKHEFLLDSLKAFGFPLKFLNVVQMLYKDINSCVILNSCTSPRFPVLRGIRQGC 664
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Match: ENSXETT00000002428.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:3:15907829:15913358:1 gene:ENSXETG00000006437.1 transcript:ENSXETT00000002428.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 86.6557 bits (213), Expect = 1.264e-19
Identity = 59/175 (33.71%), Postives = 90/175 (51.43%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            LLT ++ + I    +P+ +     I++PKP KD +  L  S+RPI+LL+   K++A ILARRL   IK   L++  Q G         +   L   L  +  S     AIA LDI  AF +V   Y+W +L+++G    F NM++LLY    +      + T N  + +G +QGC
Sbjct:  487 LLTKMYGEAISTGILPESMYEAAIILLPKPGKDPQ--LCESFRPISLLTTDVKIYAKILARRLARVIK--TLVNPDQIGFIPTKTTALNTRRLYLNLSLTP-SNTGNRAIAALDIAKAFDTVEWSYLWCVLKQLGFGPTFINMVQLLYKSPRATLRINSLCTSNFTLSRGTRQGC 656
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Match: ENSXETT00000032317.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:130520927:130524992:-1 gene:ENSXETG00000008594.1 transcript:ENSXETT00000032317.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 85.1149 bits (209), Expect = 4.867e-19
Identity = 55/175 (31.43%), Postives = 88/175 (50.29%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  LF + +     P+ L     +++PK  KD    L  S+RPI+LL+   K+FA +LARRL+  I +  ++H  Q G         +   L   L H+   +    AIA LDI  AF +V   Y+W++L   G  +++  M++LLY    +      + TP  A+ +G +QGC
Sbjct:  487 MLLKLFKEAVQLGQFPESLYEAAIVLLPKQGKDPH--LCESFRPISLLTADVKIFAKVLARRLSRVITK--IIHPDQIGFIPAKTAALNTRRLYLNLAHASAGQGAK-AIAALDITKAFDTVEWPYLWQVLTHFGFGKKYIQMVQLLYKYPVASIRINSLTTPAFALSRGTRQGC 656
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Match: ENSXETT00000040456.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:8:87387561:87390644:-1 gene:ENSXETG00000021299.1 transcript:ENSXETT00000040456.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 84.7297 bits (208), Expect = 6.171e-19
Identity = 55/175 (31.43%), Postives = 88/175 (50.29%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  LF + +     P+ L     +++PK  KD    L  S+RPI+LL+   K+FA +LARRL+  I +  ++H  Q G         +   L   L H+   +    AIA LDI  AF +V   Y+W++L   G  +++  M++LLY    +      + TP  A+ +G +QGC
Sbjct:  117 MLLKLFKEAVQLGQFPESLYEAAIVLLPKQGKDPH--LCESFRPISLLTADVKIFAKVLARRLSRVITK--IIHPDQIGFIPAKTAALNTRRLYLNLAHASAGQGAK-AIAALDITKAFDTVEWPYLWQVLTHFGFGKKYIQMVQLLYKYPVASIRINSLTTPAFALSRGTRQGC 286
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Match: rpl22l1 (ribosomal protein L22 like 1 [Source:Xenbase;Acc:XB-GENE-6073103])

HSP 1 Score: 80.4925 bits (197), Expect = 4.872e-18
Identity = 55/174 (31.61%), Postives = 89/174 (51.15%), Query Frame = 2 
Query:    8 LTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            L  LFN +     +PD ++    I++PKP KD +    +S+RPI+L++   K+ A ILARRL   I +  L+ + Q G         +   L + L  +  +  + + IA LD + AF SV   Y+W  L+ +G  E FT  ++ LY D  +       I+   A+++G +QGC
Sbjct:   15 LVSLFNDVREGAPLPDSMRRAMIIVLPKPGKDPRE--CASYRPISLMNCDAKILAKILARRLNQVITQ--LIEIDQSGFIPTRTTDINIRRLYTNLSVTHDNAGSRV-IATLDNEKAFDSVEWAYLWATLQSMGFKENFTKWIQALYRDPEATIRTNQNISLPFALQRGTRQGC 183
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Match: ENSXETT00000046003.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:KV460539.1:49812:51785:-1 gene:ENSXETG00000019210.1 transcript:ENSXETT00000046003.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 3.396e-17
Identity = 50/166 (30.12%), Postives = 90/166 (54.22%), Query Frame = 2 
Query:   41 KTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKG---GSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +++P        ++IPK  +D   TL SS+RPI+L++   K+ A +LA RLT  ++  +L+H  Q G   G   D  +     L + L+ + ++ +   A+A LD + AF S+  +Y+W++LRR G+   F   L++LY    +       ++P  ++ +G +QGC
Sbjct:  335 QSLPPSFAEALIVVIPKAGRDP--TLCSSYRPISLINTDAKILAKVLATRLTRAVQ--DLIHPDQSGFMPGRATDFNLRR---LFTNLQIT-HTNSGARAVASLDSEKAFDSIEWEYLWEVLRRFGLGARFIQWLKMLYKHPIARVRVNNTVSPTFSLHRGTRQGC 492
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Match: sp|Q03274|PO22_POPJA (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Popillia japonica OX=7064 PE=4 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 3.994e-15
Identity = 49/161 (30.43%), Postives = 87/161 (54.04%), Query Frame = 2 
Query:   47 VPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGP-IITPNIAIKQGVKQG 526
            VP    + +T +IPK   D      S+WRPI + S + ++   ILA+RL + ++    LH  QKG +  DG + ++ +L + +   +  + T   +  LD++ AF +V H  + + L+R+G+ E  +N +    +D+++    GP   T  I I++GVKQG
Sbjct:   52 VPTPWTAMRTTLIPK---DGDLENPSNWRPITIASALQRLLHRILAKRLEAAVE----LHPAQKGYARIDGTLVNSLLLDTYISSRREQRKT-YNVVSLDVRKAFDTVSHSSICRALQRLGIDEGTSNYITGSLSDSTTTIRVGPGSQTRKICIRRGVKQG 204
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Match: sp|P11369|LORF2_MOUSE (LINE-1 retrotransposable element ORF2 protein OS=Mus musculus OX=10090 GN=Pol PE=1 SV=2)

HSP 1 Score: 70.8626 bits (172), Expect = 1.877e-13
Identity = 51/177 (28.81%), Postives = 87/177 (49.15%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSS--CLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  LF+KI ++ T+P+        +IPKP KD   T + ++RPI+L+++  K+   ILA R+   IK   ++H  Q G     G     ++  S   + +    K+    I  LD + AF  + H +M K+L R G+   + NM++ +Y+   +           I +K G +QGC
Sbjct:  498 ILHKLFHKIEVEGTLPNSFYEATITLIPKPQKDP--TKIENFRPISLMNIDAKILNKILANRIQEHIKA--IIHPDQVG--FIPGMQGWFNIRKSINVIHYINKLKDKNHMIISLDAEKAFDKIQHPFMIKVLERSGIQGPYLNMIKAIYSKPVANIKVNGEKLEAIPLKSGTRQGC 668
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Match: sp|P08548|LIN1_NYCCO (LINE-1 reverse transcriptase homolog OS=Nycticebus coucang OX=9470 PE=4 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 4.821e-12
Identity = 46/178 (25.84%), Postives = 86/178 (48.31%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKG---GSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +L  LF  I  +  +P+        +IPKP KD   T   ++RPI+L+++  K+   IL  R+   IK+  ++H  Q G   GS   G       ++  ++H    KN    I  +D + AF ++ H +M + L++IG+   F  ++  +Y+  ++      +   +  ++ G +QGC
Sbjct:  490 ILLNLFQNIEKEGILPNTFYEANITLIPKPGKDP--TRKENYRPISLMNIDAKILNKILTNRIQQHIKK--IIHHDQVGFIPGS--QGWFNIRKSIN-VIQHINKLKNKDHMILSIDAEKAFDNIQHPFMIRTLKKIGIEGTFLKLIEAIYSKPTANIILNGVKLKSFPLRSGTRQGC 660
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Match: sp|Q03278|PO21_NASVI (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Nasonia vitripennis OX=7425 PE=4 SV=2)

HSP 1 Score: 66.2402 bits (160), Expect = 7.466e-12
Identity = 53/171 (30.99%), Postives = 84/171 (49.12%), Query Frame = 2 
Query:   17 LFNKIIIDKTVPDCLKSFKTIMIPK-PDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSS----FYTCGPIITPNIAIKQG 514
            LFN I+     P      +T++IPK P   D     + +RP+++ SV  + F  ILA R    I  + LL   Q+   + DG  E+ S+LS+ ++ ++  K   + IA LD+K AF SV H  +   LRR  +  E  N +  +Y ++ +      T G  I P   ++QG
Sbjct:  355 LFNMIMYHGQCPRRYLDSRTVLIPKEPGTMDP----ACFRPLSIASVALRHFHRILANR----IGEHGLLDTRQRAFIVADGVAENTSLLSAMIKEARM-KIKGLYIAILDVKKAFDSVEHRSILDALRRKKLPLEMRNYIMWVYRNSKTRLEVVKTKGRWIRPARGVRQG 516
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Match: sp|O00370|LORF2_HUMAN (LINE-1 retrotransposable element ORF2 protein OS=Homo sapiens OX=9606 PE=1 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 4.149e-10
Identity = 45/177 (25.42%), Postives = 82/177 (46.33%), Query Frame = 2 
Query:    5 LLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKG--GSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
             L  LF  I  +  +P+       I+IPKP +D   T   ++RPI+L+++  K+   ILA R+   IK+  L+H  Q G    +        S+  + ++H   +K+    I  +D + AF  +   +M K L ++G+   +  ++R +Y   ++             +K G +QGC
Sbjct:  491 FLLKLFQSIEKEGILPNSFYEASIILIPKPGRDT--TKKENFRPISLMNIDAKILNKILANRIQQHIKK--LIHHDQVGFIPGMQGWFNIRKSI--NVIQHINRAKDKNHVIISIDAEKAFDKIQQPFMLKTLNKLGIDGMYLKIIRAIYDKPTANIILNGQKLEAFPLKTGTRQGC 661
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Match: A0A159X4Q6 (ORF2-like protein (Fragment) OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 1.852e-38
Identity = 72/112 (64.29%), Postives = 82/112 (73.21%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIA 337
            KLL  LFN II    +P+   SFKTI+IPKP K   Y   SSWRPIALLS  YK+F SIL+RRLT WI  N LLH GQKGGS  +GCVEHN+VL++ LEHSKYSK  P+AIA
Sbjct:  208 KLLARLFNIIIDSGQIPNDWLSFKTILIPKPGKSGDYDDTSSWRPIALLSTSYKIFTSILSRRLTKWIIENKLLHPGQKGGSRFEGCVEHNAVLTAVLEHSKYSKKAPLAIA 319
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Match: A0A4Y2C3J9 (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 (Fragment) OS=Araneus ventricosus OX=182803 GN=PO21_34 PE=4 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.124e-35
Identity = 74/176 (42.05%), Postives = 107/176 (60.80%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            + L  LFN  +  + VP   K   TI++PK  K D  +L  +WRPIAL S  YK+F   LA RL+SW ++ ++L   QKG + HDG +EHN VL   LE ++  +   + IAWLD+ +AFG++PH  +++ L   G  E+FT+++R +Y+D S+    G   T  I IK GVKQGC
Sbjct:   45 QFLQALFNVCVHPRRVPPVWKKSTTILLPK--KGD-LSLPCNWRPIALSSTAYKLFTKCLAARLSSWCEQYSILSPCQKGFTPHDGILEHNFVLQQSLEQARLQRKE-LCIAWLDVTNAFGALPHSAIFEALTAAGTGEQFTDIIRDIYSDASTQILSGLSTTKPIGIKSGVKQGC 216
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Match: A0A4Y2SYT3 (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 OS=Araneus ventricosus OX=182803 GN=PO22_2 PE=4 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 1.455e-34
Identity = 72/171 (42.11%), Postives = 104/171 (60.82%), Query Frame = 2 
Query:   17 LFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            LFN  +  + VP   K   TI++PK  K D  +L  +WRPIAL S  YK+F   +A RL++W ++ N+L   QKG + HDG +EHN VL   LE ++  +   I IAWLD+ +AFG++PH  +++ L   G  E+F +++R +Y+D S+    G   T  I IK GVKQGC
Sbjct:    4 LFNACVHLRRVPPAWKKSTTILLPK--KGD-LSLPCNWRPIALSSTAYKLFTKCIAARLSTWCEQYNILSPCQKGFTPHDGILEHNFVLQQSLEQARLQRKE-ICIAWLDVTNAFGALPHSDIFEALTAAGTGEQFVDVIRDIYSDASTQILSGQSTTKPIEIKSGVKQGC 170
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Match: A0A4Y1ZUE0 (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 OS=Araneus ventricosus OX=182803 GN=PO21_53 PE=4 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 5.423e-34
Identity = 74/176 (42.05%), Postives = 106/176 (60.23%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            + L  LFN  +  + VP   K   TI++PK  K D  +L  +WRPIAL S  YK+F   LA RL++W  + ++L   QKG + HDG +EHN VL   LE ++  +   I IAWLD+ +AFG++PH  +++ L   G  E+FT+++R +Y+D S+    G   T  I IK GVKQGC
Sbjct: 1000 QFLQALFNACVHLRRVPPVWKKSTTILLPK--KGD-LSLPCNWRPIALSSTAYKLFTKCLAARLSTWCDQYSILSPCQKGFTPHDGILEHNFVLQQSLEQARLQRKE-ICIAWLDVTNAFGALPHSAIFEALTAAGTGEQFTDLIRDIYSDASTQILAGQSTTNPIGIKSGVKQGC 1171
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Match: A0A4Y2NZ92 (Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 OS=Araneus ventricosus OX=182803 GN=PO21_52 PE=4 SV=1)

HSP 1 Score: 136.732 bits (343), Expect = 6.732e-34
Identity = 73/176 (41.48%), Postives = 107/176 (60.80%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            + L  LFN  +  + VP   K   TI++PK  K D  +L  +WRPIAL S  YK+F   LA RL++W  + ++L   QKG + HDG +EHN VL   LE ++  +   + IAWLD+ +AFG++PH  +++ L   G  E+FT+++R +Y+D+S+    G   T  I IK GVKQGC
Sbjct: 1100 QFLQALFNACVHLRRVPPVWKKSTTILLPK--KGD-LSLPCNWRPIALSSTAYKLFTKCLAARLSAWCDQYSILSPCQKGFTPHDGILEHNFVLQQSLEQARLQRKE-LCIAWLDVTNAFGALPHSAIFEALTAAGTGEQFTDIIRDIYSDSSTQILAGQSTTNPIGIKSGVKQGC 1271
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Match: ENSAMXT00000034831.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:16211297:16215948:1 gene:ENSAMXG00000034228.1 transcript:ENSAMXT00000034831.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 99.3673 bits (246), Expect = 3.252e-24
Identity = 59/178 (33.15%), Postives = 101/178 (56.74%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVG-QKGG-SIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KL+  ++ K II    P        ++IPK +KD     +  +RPI+LL+V  K+F S++ARRL +++KRNNL+    QK G +   GC+EHNS++   ++ ++  K   + + +LD+ +AFGSVPH  +WK      V EE + +++  + D    ++ G  +T    ++ G+  GC
Sbjct:  412 KLMAIVWKKGII----PKEWHRAGGVLIPK-EKDS--VAIDQFRPISLLNVEGKIFFSVVARRLATYLKRNNLIDTSVQKAGIAGFSGCIEHNSMIWHQIQTARAEKKD-LHVVFLDLANAFGSVPHALLWKAFNFFRVPEEISRLVKAYFEDIQFCFSVGECVTSWQRLEIGIMAGC 581
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Match: ENSAMXT00000034560.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000712.1:195631:202616:-1 gene:ENSAMXG00000042811.1 transcript:ENSAMXT00000034560.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.337 bits (194), Expect = 2.745e-17
Identity = 48/173 (27.75%), Postives = 86/173 (49.71%), Query Frame = 2 
Query:    8 LTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQG 526
            L  L+   ++   VP   K  +T +IPK    +    V +WRPI + S+I ++F+ I+A RL     R   ++  Q+G     GC E+  VL   + H K  + + +A+ ++D   AF S+ H+++   L +  + +    +++  Y D  +        +P+I +K GVKQG
Sbjct:  464 LERLYTAWMVAGVVPKAFKECRTTLIPKSTSKEALEEVGNWRPITIGSLILRLFSKIMAERLA----RACPINPRQRGFISAPGCAENLKVLQGLIGHCK-KERSQLAVVFVDFARAFDSISHEHILSALGQRQLDQHVIKLIQSAYVDCVTRIIMDGAKSPDILMKVGVKQG 631
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Match: ENSAMXT00000055550.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:16555187:16560144:-1 gene:ENSAMXG00000035203.1 transcript:ENSAMXT00000055550.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 5.006e-17
Identity = 48/165 (29.09%), Postives = 87/165 (52.73%), Query Frame = 2 
Query:   41 KTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSI--HDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            +T+P   +    ++IPK +KD   + +  +R I LL+V  KVF SI+A+RLT ++K NN++    +   I    GC+EH S++   ++ ++  +   + + +LD+ +AFGS+PH  +W       +    TNM+R  + D           T   +++ G+  GC
Sbjct:  364 QTIPKAWRRAGGVLIPK-EKDA--SNIGQFRQINLLNVEGKVFFSIVAKRLTKYLKENNMIDTSVQKAGIPGFSGCLEHISMIWHQIQSAR-KEGRDLHVLFLDLANAFGSIPHSLIWAAFDFFHIPNTITNMVRNYFQDLQFCIQTTEYTTSWQSLEVGIMAGC 524
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Match: ENSAMXT00000033573.1 (pep primary_assembly:Astyanax_mexicanus-2.0:3:31407009:31410218:-1 gene:ENSAMXG00000030324.1 transcript:ENSAMXT00000033573.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.411 bits (189), Expect = 1.302e-16
Identity = 47/153 (30.72%), Postives = 80/153 (52.29%), Query Frame = 2 
Query:   77 IMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHD--GCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            + IPK +       +  +R I+LLSV  K+F SILARRLT ++  N+ +    + G I    GC+EH  V++  +  ++ +K   +A+ WLD+ +A+GS+PH  +   L R  V  +   ++   Y   S   + G I +    ++ G+  GC
Sbjct:  318 VWIPKEEVSKN---IDQFRIISLLSVEGKIFFSILARRLTDFLSSNHYIDTSVQKGGIPGVPGCLEHTGVVTQLIREARENKGD-LAVLWLDLANAYGSIPHKLVQTTLERHHVPGQVAELIMNYYDQFSMRVSTGSITSEWHRVEVGIITGC 466
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Match: ENSAMXT00000048276.1 (pep primary_assembly:Astyanax_mexicanus-2.0:17:7857318:7859867:1 gene:ENSAMXG00000040121.1 transcript:ENSAMXT00000048276.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.0258 bits (188), Expect = 1.767e-16
Identity = 50/150 (33.33%), Postives = 82/150 (54.67%), Query Frame = 2 
Query:   80 MIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++ KP KD   T  SS+RP++LL+   KVFA +LA+RL S I   +L+H  Q G        ++   L   LE +  S+    A+  LD + AF  +   ++W +L+R G    F +M+  LYT+ S+  + G +I+    +++G +QGC
Sbjct:  517 LLLKPGKDS--TECSSYRPLSLLNTDVKVFAKVLAKRLDSVIP--DLIHSDQTGFIRSRLASDNLRRLFHILEFAP-SQMLGSAVLSLDAEKAFDRLEWPFLWAVLKRFGFGSAFIHMIFTLYTNPSACVSTGHMISAKFLLERGTRQGC 661
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Match: ENSORLT00000040357.1 (pep primary_assembly:ASM223467v1:14:28942701:28945517:1 gene:ENSORLG00000024817.1 transcript:ENSORLT00000040357.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 82.0333 bits (201), Expect = 2.773e-18
Identity = 54/180 (30.00%), Postives = 91/180 (50.56%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQ----KGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++L   FN+ I ++ +   +K     ++PKP KD    L+ +WRPI LL   YK+ A I A RL S I +  ++   Q    KG  IH     H  ++   L++++      + I +LD   AF S+ H +++  L+  G   +F N++++ Y D SS        + N  + +GV+QGC
Sbjct:  501 EMLFEAFNECIDEQMLSPTMKRGIISLLPKPGKD--VLLIDNWRPITLLCCDYKILAHIYANRLKSGISQ--IIDESQSAFIKGRHIH----HHTRLILDILDYNQIIPQDSL-ILYLDFFKAFDSLEHAFLFNALKTFGFESKFCNIIKMFYKDISSNIAINRGFSNNFPVNRGVRQGC 671
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Match: ENSORLT00000036683.1 (pep primary_assembly:ASM223467v1:19:23029986:23032853:-1 gene:ENSORLG00000028041.1 transcript:ENSORLT00000036683.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.6481 bits (200), Expect = 4.497e-18
Identity = 47/171 (27.49%), Postives = 90/171 (52.63%), Query Frame = 2 
Query:   17 LFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++ + I+ + +   +K     +IPKP+KD    ++ +WRPI LL+V YK+ A + A+RL S +    ++   Q G   +     +  ++   L++S++  +  + I +LD   AF +V H +++  L+  G  E F ++ ++ Y D SS     P  +   +I + V+QGC
Sbjct:  212 MYKECIVQQEMTATMKQGLITLIPKPNKDP--VMIENWRPITLLNVDYKILALVYAQRLKSNLHE--IISETQSGFMKNRHISNNIRLILDLLDYSEHIDSEAL-ILFLDFYKAFDTVEHPFLYNALKLFGFGENFISIAKMFYKDISSSILLYPNTSQRFSINRSVRQGC 377
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Match: ENSORLT00000028058.1 (pep primary_assembly:ASM223467v1:18:21516917:21520645:1 gene:ENSORLG00000027382.1 transcript:ENSORLT00000028058.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 5.152e-18
Identity = 47/171 (27.49%), Postives = 90/171 (52.63%), Query Frame = 2 
Query:   17 LFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++ + I+ + +   +K     +IPKP+KD    ++ +WRPI LL+V YK+ A + A+RL S +    ++   Q G   +     +  ++   L++S++  +  + I +LD   AF +V H +++  L+  G  E F ++ ++ Y D SS     P  +   +I + V+QGC
Sbjct:  499 MYKECIVQQEMTATMKQGLITLIPKPNKDP--VMIENWRPITLLNVDYKILALVYAQRLKSNLHE--IISETQSGFMKNRHISNNIRLILDLLDYSEHIDSEAL-ILFLDFYKAFDTVEHPFLYNALKLFGFGENFISIAKMFYKDISSSILLYPNTSQRFSINRSVRQGC 664
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Match: ENSORLT00000043337.1 (pep primary_assembly:ASM223467v1:9:26106542:26110291:1 gene:ENSORLG00000021884.1 transcript:ENSORLT00000043337.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 79.7221 bits (195), Expect = 2.019e-17
Identity = 53/180 (29.44%), Postives = 91/180 (50.56%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQ----KGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++L   FN+ I ++ +   +K     ++PKP KD    L+ +WRPI LL   YK+ A I A RL S I +  ++   Q    KG  IH     H  ++   L++++      + I +LD   AF S+ H +++  L+  G   +F N++++ Y D SS        + +  + +GV+QGC
Sbjct:  500 EMLFEAFNECIDEQMLSPTMKRGVISLLPKPGKD--VLLIDNWRPITLLCCDYKILAHIYANRLKSGISQ--IIDESQSAFIKGRHIH----HHTRLILDILDYNQIIPQDSL-ILFLDFFKAFDSLEHAFLFNALKTFGFESKFCNIIKMFYKDISSNIALNRGFSNSFPVNRGVRQGC 670
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Match: ENSORLT00000044124.1 (pep primary_assembly:ASM223467v1:4:5412351:5416070:1 gene:ENSORLG00000022718.1 transcript:ENSORLT00000044124.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 78.5666 bits (192), Expect = 4.746e-17
Identity = 52/180 (28.89%), Postives = 91/180 (50.56%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQ----KGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            ++L   FN+ I ++ +   +K     ++PKP KD    L+ +WRPI LL   YK+ A I A RL S I +  ++   Q    KG  IH     H  ++   +++++      + I +LD   AF S+ H +++  L+  G   +F N++++ Y D SS        + +  + +GV+QGC
Sbjct:  490 EMLFEAFNECIDEQMLSPTMKRGIISLLPKPGKD--VLLIDNWRPITLLCCDYKILAHIYANRLKSGISQ--IIDESQSAFIKGRHIH----HHTRLILDIIDYNQIIPQESL-ILFLDFFKAFDSLEHAFLFNALKTFGFESKFCNIIKMFYKDISSNIALNRGFSNSFPVNRGVRQGC 660
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Match: SMESG000079542.1 (SMESG000079542.1)

HSP 1 Score: 315.849 bits (808), Expect = 4.750e-102
Identity = 143/176 (81.25%), Postives = 162/176 (92.05%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KLLT L+NKII + T+PD  KSFKT+M PKPDK DKY L+SSWRPIALLSV+YK+FASIL+RRLTSW+ RNNLLH+GQKGGS+HDGCVEHNSVLSSCLEHSKYSK+TPI IA+LDIKDAFGSVPHDYMWK+LR IGV E+FTN L+LLYT+TSS+YTCGPI+TPNI IKQGVKQGC
Sbjct:  376 KLLTLLYNKIITENTMPDVWKSFKTLMTPKPDKGDKYNLISSWRPIALLSVVYKIFASILSRRLTSWVNRNNLLHIGQKGGSVHDGCVEHNSVLSSCLEHSKYSKDTPIIIAFLDIKDAFGSVPHDYMWKILRHIGVGEKFTNTLKLLYTETSSYYTCGPIVTPNIPIKQGVKQGC 551
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Match: SMESG000021486.1 (SMESG000021486.1)

HSP 1 Score: 300.827 bits (769), Expect = 1.074e-94
Identity = 139/176 (78.98%), Postives = 157/176 (89.20%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KLLTFLFNKII++K +PD  KSFKT++ PKP+KD KY  VSSWRPIALLSVIYKVFAS LA RLT WI  NNLLH+GQKGGS HDGCVEHNS+LS+ LEHSKYSKN P+AIAWLDIKDAFGSVPHDYMW LLR IGV E+FT++L+LLY+DTS+FY+CGPI+TPNI IKQGVKQGC
Sbjct: 3091 KLLTFLFNKIIVNKIIPDSWKSFKTLLTPKPNKDGKYDDVSSWRPIALLSVIYKVFASCLASRLTYWINTNNLLHIGQKGGSRHDGCVEHNSILSAALEHSKYSKNCPLAIAWLDIKDAFGSVPHDYMWSLLRFIGVGEDFTSILQLLYSDTSTFYSCGPILTPNIPIKQGVKQGC 3266

HSP 2 Score: 300.827 bits (769), Expect = 1.074e-94
Identity = 139/176 (78.98%), Postives = 157/176 (89.20%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KLLTFLFNKII++K +PD  KSFKT++ PKP+KD KY  VSSWRPIALLSVIYKVFAS LA RLT WI  NNLLH+GQKGGS HDGCVEHNS+LS+ LEHSKYSKN P+AIAWLDIKDAFGSVPHDYMW LLR IGV E+FT++L+LLY+DTS+FY+CGPI+TPNI IKQGVKQGC
Sbjct: 5447 KLLTFLFNKIIVNKIIPDSWKSFKTLLTPKPNKDGKYDDVSSWRPIALLSVIYKVFASCLASRLTYWINTNNLLHIGQKGGSRHDGCVEHNSILSAALEHSKYSKNCPLAIAWLDIKDAFGSVPHDYMWSLLRFIGVGEDFTSILQLLYSDTSTFYSCGPILTPNIPIKQGVKQGC 5622

HSP 3 Score: 68.1662 bits (165), Expect = 1.368e-13
Identity = 30/46 (65.22%), Postives = 37/46 (80.43%), Query Frame = 2 
Query:  392 LLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            LL+ + VS EF N+L+LLYTDTSSFY C  + TP+I IK+GVKQGC
Sbjct:  902 LLKHMNVSAEFVNILQLLYTDTSSFYQCNQMQTPDIPIKKGVKQGC 947
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Match: SMESG000021486.1 (SMESG000021486.1)

HSP 1 Score: 300.827 bits (769), Expect = 1.194e-94
Identity = 139/176 (78.98%), Postives = 157/176 (89.20%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KLLTFLFNKII++K +PD  KSFKT++ PKP+KD KY  VSSWRPIALLSVIYKVFAS LA RLT WI  NNLLH+GQKGGS HDGCVEHNS+LS+ LEHSKYSKN P+AIAWLDIKDAFGSVPHDYMW LLR IGV E+FT++L+LLY+DTS+FY+CGPI+TPNI IKQGVKQGC
Sbjct: 3062 KLLTFLFNKIIVNKIIPDSWKSFKTLLTPKPNKDGKYDDVSSWRPIALLSVIYKVFASCLASRLTYWINTNNLLHIGQKGGSRHDGCVEHNSILSAALEHSKYSKNCPLAIAWLDIKDAFGSVPHDYMWSLLRFIGVGEDFTSILQLLYSDTSTFYSCGPILTPNIPIKQGVKQGC 3237

HSP 2 Score: 300.827 bits (769), Expect = 1.194e-94
Identity = 139/176 (78.98%), Postives = 157/176 (89.20%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            KLLTFLFNKII++K +PD  KSFKT++ PKP+KD KY  VSSWRPIALLSVIYKVFAS LA RLT WI  NNLLH+GQKGGS HDGCVEHNS+LS+ LEHSKYSKN P+AIAWLDIKDAFGSVPHDYMW LLR IGV E+FT++L+LLY+DTS+FY+CGPI+TPNI IKQGVKQGC
Sbjct: 5389 KLLTFLFNKIIVNKIIPDSWKSFKTLLTPKPNKDGKYDDVSSWRPIALLSVIYKVFASCLASRLTYWINTNNLLHIGQKGGSRHDGCVEHNSILSAALEHSKYSKNCPLAIAWLDIKDAFGSVPHDYMWSLLRFIGVGEDFTSILQLLYSDTSTFYSCGPILTPNIPIKQGVKQGC 5564

HSP 3 Score: 68.1662 bits (165), Expect = 1.355e-13
Identity = 30/46 (65.22%), Postives = 37/46 (80.43%), Query Frame = 2 
Query:  392 LLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            LL+ + VS EF N+L+LLYTDTSSFY C  + TP+I IK+GVKQGC
Sbjct:  902 LLKHMNVSAEFVNILQLLYTDTSSFYQCNQMQTPDIPIKKGVKQGC 947
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Match: SMESG000078596.1 (SMESG000078596.1)

HSP 1 Score: 249.98 bits (637), Expect = 4.005e-77
Identity = 117/171 (68.42%), Postives = 138/171 (80.70%), Query Frame = 2 
Query:   17 LFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYTDTSSFYTCGPIITPNIAIKQGVKQGC 529
            + N + +D  +PD  KSFKT++I KP K DKY  VSSWRPIALLSVIYK+F S LA RLT  I +NNLLH+GQKG S HDGCVEHNS+LSS LEHSKY KN+ +AIAWLDIKDAFGSVPH YMW LLR +GV EEF  ++  + +D S+FY+CGPI+TPNIAI+QGVKQGC
Sbjct:  722 IINDVDVD-VIPDSWKSFKTLLIQKPSKGDKYDSVSSWRPIALLSVIYKLFTSCLANRLTFCINKNNLLHIGQKGDSRHDGCVEHNSILSSALEHSKYGKNSQLAIAWLDIKDAFGSVPHAYMWSLLRFVGVDEEFVTIIERMDSDKSTFYSCGPILTPNIAIRQGVKQGC 891
[Close]
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Match: SMESG000071441.1 (SMESG000071441.1)

HSP 1 Score: 243.047 bits (619), Expect = 2.555e-76
Identity = 111/138 (80.43%), Postives = 125/138 (90.58%), Query Frame = 2 
Query:    2 KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLSVIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEHSKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVS 415
            KLLT L+NKII + T+PD  K FKT+MIPKPDK DKY L+SSWRPI LLSV+YK+FASILARRLTSW+ RNNLLH+GQKGGS+HDGCVEHNSVL SCLEHSKYSK+TPI IA+LDIKDAFGSVPHDYMWK+LR IGV+
Sbjct:  136 KLLTLLYNKIITENTMPDVWKYFKTLMIPKPDKGDKYNLISSWRPITLLSVVYKIFASILARRLTSWVNRNNLLHIGQKGGSVHDGCVEHNSVLLSCLEHSKYSKDTPIIIAFLDIKDAFGSVPHDYMWKILRHIGVA 273
The following BLAST results are available for this feature:
BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
BX284696.18.211e-2027.84pep chromosome:GRCz11:7:42935126:42939263:1 gene:E... [more]
BX511246.18.534e-2027.84pep chromosome:GRCz11:23:9353552:9357627:1 gene:EN... [more]
si:dkeyp-88h4.22.422e-1832.34si:dkeyp-88h4.2 [Source:ZFIN;Acc:ZDB-GENE-131121-1... [more]
CU024870.23.240e-1832.34pep chromosome:GRCz11:25:23489979:23495448:1 gene:... [more]
BX544877.23.468e-1832.34pep chromosome:GRCz11:25:25310063:25315481:1 gene:... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000002428.11.264e-1933.71pep primary_assembly:Xenopus_tropicalis_v9.1:3:159... [more]
ENSXETT00000032317.14.867e-1931.43pep primary_assembly:Xenopus_tropicalis_v9.1:1:130... [more]
ENSXETT00000040456.16.171e-1931.43pep primary_assembly:Xenopus_tropicalis_v9.1:8:873... [more]
rpl22l14.872e-1831.61ribosomal protein L22 like 1 [Source:Xenbase;Acc:X... [more]
ENSXETT00000046003.13.396e-1730.12pep primary_assembly:Xenopus_tropicalis_v9.1:KV460... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q03274|PO22_POPJA3.994e-1530.43Retrovirus-related Pol polyprotein from type-1 ret... [more]
sp|P11369|LORF2_MOUSE1.877e-1328.81LINE-1 retrotransposable element ORF2 protein OS=M... [more]
sp|P08548|LIN1_NYCCO4.821e-1225.84LINE-1 reverse transcriptase homolog OS=Nycticebus... [more]
sp|Q03278|PO21_NASVI7.466e-1230.99Retrovirus-related Pol polyprotein from type-1 ret... [more]
sp|O00370|LORF2_HUMAN4.149e-1025.42LINE-1 retrotransposable element ORF2 protein OS=H... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A159X4Q61.852e-3864.29ORF2-like protein (Fragment) OS=Schmidtea mediterr... [more]
A0A4Y2C3J91.124e-3542.05Retrovirus-related Pol polyprotein from type-1 ret... [more]
A0A4Y2SYT31.455e-3442.11Retrovirus-related Pol polyprotein from type-1 ret... [more]
A0A4Y1ZUE05.423e-3442.05Retrovirus-related Pol polyprotein from type-1 ret... [more]
A0A4Y2NZ926.732e-3441.48Retrovirus-related Pol polyprotein from type-1 ret... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000034831.13.252e-2433.15pep primary_assembly:Astyanax_mexicanus-2.0:3:1621... [more]
ENSAMXT00000034560.12.745e-1727.75pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000055550.15.006e-1729.09pep primary_assembly:Astyanax_mexicanus-2.0:1:1655... [more]
ENSAMXT00000033573.11.302e-1630.72pep primary_assembly:Astyanax_mexicanus-2.0:3:3140... [more]
ENSAMXT00000048276.11.767e-1633.33pep primary_assembly:Astyanax_mexicanus-2.0:17:785... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000040357.12.773e-1830.00pep primary_assembly:ASM223467v1:14:28942701:28945... [more]
ENSORLT00000036683.14.497e-1827.49pep primary_assembly:ASM223467v1:19:23029986:23032... [more]
ENSORLT00000028058.15.152e-1827.49pep primary_assembly:ASM223467v1:18:21516917:21520... [more]
ENSORLT00000043337.12.019e-1729.44pep primary_assembly:ASM223467v1:9:26106542:261102... [more]
ENSORLT00000044124.14.746e-1728.89pep primary_assembly:ASM223467v1:4:5412351:5416070... [more]
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BLAST of Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000079542.14.750e-10281.25SMESG000079542.1[more]
SMESG000021486.11.074e-9478.98SMESG000021486.1[more]
SMESG000021486.11.194e-9478.98SMESG000021486.1[more]
SMESG000078596.14.005e-7768.42SMESG000078596.1[more]
SMESG000071441.12.555e-7680.43SMESG000071441.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30024599 ID=SMED30024599|Name=Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2|organism=Schmidtea mediterranea sexual|type=transcript|length=531bp
CAAATTACTGACATTTCTCTTCAACAAAATTATCATTGATAAAACTGTTC
CAGATTGTCTAAAGTCTTTCAAAACAATAATGATTCCAAAGCCTGATAAA
GATGACAAATACACTTTAGTTTCTTCATGGCGTCCAATAGCTCTATTGTC
AGTCATTTACAAAGTTTTTGCATCAATATTAGCAAGGCGCTTGACTAGTT
GGATAAAGAGAAACAATTTACTACATGTTGGACAAAAAGGAGGTTCGATC
CACGATGGCTGTGTTGAGCATAATTCTGTTCTTTCCTCTTGTCTAGAACA
CTCAAAATATAGTAAAAACACTCCAATTGCAATTGCTTGGCTTGATATTA
AGGATGCCTTTGGTAGTGTTCCTCATGATTACATGTGGAAATTGCTGCGT
CGGATTGGGGTCAGTGAAGAGTTTACCAATATGTTGAGACTATTATATAC
TGATACCAGCTCATTCTATACATGTGGTCCTATTATCACACCAAACATTG
CCATTAAACAGGGTGTCAAACAAGGATGCCC
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protein sequence of SMED30024599-orf-1

>SMED30024599-orf-1 ID=SMED30024599-orf-1|Name=SMED30024599-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=176bp
KLLTFLFNKIIIDKTVPDCLKSFKTIMIPKPDKDDKYTLVSSWRPIALLS
VIYKVFASILARRLTSWIKRNNLLHVGQKGGSIHDGCVEHNSVLSSCLEH
SKYSKNTPIAIAWLDIKDAFGSVPHDYMWKLLRRIGVSEEFTNMLRLLYT
DTSSFYTCGPIITPNIAIKQGVKQGC
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0003676nucleic acid binding
GO:0003964RNA-directed DNA polymerase activity
GO:0004518nuclease activity
GO:0004519endonuclease activity
GO:0016740transferase activity
GO:0016779nucleotidyltransferase activity
GO:0016787hydrolase activity
Vocabulary: INTERPRO
TermDefinition
IPR000477RT_dom
IPR001633EAL_dom
Vocabulary: biological process
TermDefinition
GO:0006278RNA-dependent DNA biosynthetic process
GO:0090305nucleic acid phosphodiester bond hydrolysis